LOCUS       DATTYN010000001       147641 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.01, whole genome shotgun sequence.
ACCESSION   DATTYN010000001 DATTYN010000000
VERSION     DATTYN010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 147641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 147641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..147641
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.01"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(156..519)
                     /locus_tag="VB649_000001"
                     /pseudo
     CDS             complement(156..519)
                     /locus_tag="VB649_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558053.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(940..1473)
                     /locus_tag="VB649_000002"
     CDS             complement(940..1473)
                     /locus_tag="VB649_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEP1668993.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFS
                     KAYITIWYKRYLELKNR"
     gene            complement(1553..2329)
                     /gene="recX"
                     /locus_tag="VB649_000003"
     CDS             complement(1553..2329)
                     /gene="recX"
                     /locus_tag="VB649_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEP1668994.1"
                     /translation="MKITKIEKKKRLYLIELDNDESLYVTEDTIVRFMLSKDKVLDND
                     QLEDMKHFAQLSYGKNLALYFLSFQQRSNKQVADYLRKHEIEEHIIADIITQLQEEQW
                     IDDTKLADTYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFSQLAQKVSQK
                     LFDKYQEKLPPKALKDKITQALLTKGFSYDLAKHSLNHLNFDQDNQEIEDLLDKELDK
                     QYRKLSRKYDGYTLKQKLYQALYRKGYNSDDINCKLRNYL"
     gene            2444..3799
                     /gene="rlmD"
                     /locus_tag="VB649_000004"
     CDS             2444..3799
                     /gene="rlmD"
                     /locus_tag="VB649_000004"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEP1668995.1"
                     /translation="MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGENIFC
                     QITAVKRNFAEAKLLTVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQ
                     ALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPID
                     NCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSK
                     EVRLANFFGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFAL
                     SPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDI
                     IPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAVIVDPPRTGLDDKLL
                     KTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKR
                     V"
     gene            4464..5819
                     /gene="rocA"
                     /locus_tag="VB649_000005"
     CDS             4464..5819
                     /gene="rocA"
                     /locus_tag="VB649_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RocA"
                     /protein_id="HEP1668996.1"
                     /translation="MLEDFLQFLGFIFLDIIEIMLTLKLFSFVSAIPLRLKNIFYLSL
                     SMVLFQVVFWAFFPDHFILDVVMLAQFLFFALIALYYGKSIKAKFLMFYAFFPLVSIS
                     LVKRFIVFFVMPLFGMPYSVVKHNTLLIYSITCFSIFLIYRCIQVFHFDFSTWRQYFQ
                     SHRASKLLVFTNSSMALYYLCVQGIDVMSPSLSGLATTTARSIIVLFYFILFLTLLIH
                     LERYVKQNSIEAIVQQKEYRELINYSQHLGLLYQDIQELRQLLTTVSSRLKIGIEQND
                     ISIVRLTYEGILNAEKNNVKDDRLDLTCLDKLQVEAIRHIVLAKLIEAKNKKLKVEAS
                     IPNCIATFFLEVVDFTKLLSFLLDNAIEMSLETKQPCLSIAFLDQNHKLVIVIQSSTK
                     QGQDDSQSVFAIPALKKRDDWQFDLRNVTTILNRYDYLTISSQIHDGILTQLIEIAKP
                     D"
     gene            complement(5920..8625)
                     /locus_tag="VB649_000006"
     CDS             complement(5920..8625)
                     /locus_tag="VB649_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEP1668997.1"
                     /translation="MATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTNP
                     NFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVR
                     NMLIGKEDCDKWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEISWQGPDDSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAER
                     FASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENL
                     STVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAI
                     DTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKTYHFGQRFPKEVYQEAQEYLARLSQ
                     SFQIIDTSGQVRPEAEILGTSIAFDYDLSKRTFREPYFAIKVRLRLPITLPAMSWKTL
                     ALQLGNETAPSATVPLYDDSNQCLENEFLKVMIQTDGRLTITDKQSEVSYQDLLQFED
                     CGDIGNEYISRQPNHDQPFYADQGTTKLNIISNTAQVAELEIQQTFAIPVSADKLLQA
                     EMEAVIDITERQSGRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPT
                     HLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGEKGVTIGNYGLNE
                     YEILPDSNTIAITLLRSVGEMGDWGYFPTPEAQCLGQHSLSYSFESIDRQTQFASYWR
                     AQEGQVPILVEQTSHHTGSLRAEHSYVTGADDQVALTAFKRRPSDNALITRSYNLSND
                     KTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ"
     gene            complement(8640..9926)
                     /locus_tag="VB649_000007"
     CDS             complement(8640..9926)
                     /locus_tag="VB649_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEP1668998.1"
                     /translation="MTRPIPTSVSQFMAKVESLCGDQHPDWALNFKTSFTNTLETTLK
                     TYEDGTSFLLTGDIPAMWLRDSTAQMKPYLFLAKEDEEIRKIIAGLVKRQFRYICIDP
                     YANAFNEEANEKGHQTDHTQMNPWIWERKYEIDSLCYPIQLAYLLYRETGSTDQFNDD
                     FHRGVELILDLWTVEQDHAQSPYLFERDTWRKEDTLTHAGKGSPVAPTGMTWSGFRPS
                     DDACQYGYLIPSNMFAVVVLSYLEDLYNNLFHNEPIATRAKQLKEAIQSGIADHALVQ
                     NSKGETIYAYEVDGLGQFSIMDDANIPSLLAAPYLGFCAKDDPIYLATRRTIFSQENP
                     YYYQGNAAAGIGSSHTPENYIWHIALALQGLTALDQDSKKEMLDLLVATDAGTHLMHE
                     GFDVNDPYQYTREWFSWANMMFCELLLDYLGFSIAP"
     gene            10059..11099
                     /locus_tag="VB649_000008"
     CDS             10059..11099
                     /locus_tag="VB649_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP1668999.1"
                     /translation="MTKLLYKKIYHFIKEQIESGRLQIGDRLPTEKELSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVAEKQVTSPEANKDLLLILPFASDYELGDYAKGIM
                     TSIAETGYRLMVQLASTVRLDTLSDYAGIIYYPEDVNHSIDFLFYCDHHHIPLVLLDK
                     SLDLFQFPSVVADNKGGACQLTQHLIEQGCDQISFVATGSFGEVSSVRDRYLGYLAAM
                     AESSLKSHYFPKTETETTDAYLDRLVKTLSETTATKRGLVVENDWLAIQLTQKITQVG
                     LSIPDQVAIVGFDNSQASRLLSPKLSTAAQDFYQMGQEAAKVLLQIIHEPDQAVVSCQ
                     LPVQVFIRESSH"
     gene            11150..12844
                     /locus_tag="VB649_000009"
     CDS             11150..12844
                     /locus_tag="VB649_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase"
                     /protein_id="HEP1669000.1"
                     /translation="MTIYHTLKDYQEVMTRGDYLVFDTPLTCRFIGRFFRFENQKALL
                     AELATSKYFQWIEEGQAEVTMKHFFNRQLAKDAFTLKVSEDKEIIIESQNLRGFRYAQ
                     EALLKVMTFKGNKLYLPIVSVKHSPSFAMRGIIEGFYGTPWTREERLDCLRFIGRKRM
                     NTYMYAPKDDDYQRKQWRDLYPEDWVTYFKELLAVAKEEGIDFWYMISPGLDFDYTKE
                     ADYQLLYQKLQQLLALGVCHFGLLLDDIDYQIVDAVERRFKKTAYAQAHLATEVHHFL
                     NQQHAAPELVICPTEYDNHHDSIYLQELSERIPKEVVFFWTGPSTLASQISQADIETM
                     AAVYQRPIIIWDNIPVNDYQKDPERLFLTPFANRSPFLCQSDYQVKGIVSNPMISWEL
                     SKLTLTDMSHYLWDANRYQPSHSWLETLTDYTEDTELALALQAFAWHNGNRHLHRDLP
                     FEVEEALLAKNVSTLSAWVDELVERVNTLRKLDKPAFQQAIAPWFERVAKDQDFWQAM
                     LNQEPQLETLYADLQEDKHRIGSDIPSRYYRIYYQQQDKLTANQGQVTQARPEDYA"
     gene            12869..14311
                     /locus_tag="VB649_000010"
     CDS             12869..14311
                     /locus_tag="VB649_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP1669001.1"
                     /translation="MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYD
                     YVGPDTASDAYHQIESDLTLLASLGHNSYRTSIQWTRLIDDFEQATINPDGLAYYNRV
                     IDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFQEFGDRVKDW
                     FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRQGPAELSDGR
                     IGTILNLTPAYPASQSEADMAAAHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLW
                     QSTPEELALIAENRVDYLGLNFYHPKRVKAPDVIPVISPSWSPEWYYDPYLMPGRRMN
                     VDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEERYRDETGQIQDDYRIQF
                     LKEHLTYLHKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASA
                     YWFKKVATHNRLISLEVMEEFGGSASHLSD"
     gene            complement(14922..15800)
                     /locus_tag="VB649_000011"
     CDS             complement(14922..15800)
                     /locus_tag="VB649_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP1669002.1"
                     /translation="MSLLCIDIGGTSLKFALCHNGQLSQQSSFPTPSSLEKFYQLLDQ
                     EVARYSAYHFSGIAISSPGAVNKEKGVIEGASAIPYIHHFKIQEALEERLHYPISIEN
                     DANCAALAEATLGAGKGASSLAMLVLGTGVGGSLVIDGKIYHGAHLFGGEFGFMIMND
                     RYQTFSQLGTVVNMAKRYSAIVNNGKDYTGKAVLALTEQGDPLALKERQVFLQSLAIG
                     IFNIQHAFDPQLILIGGGVSQADFLLSAIEAELDKLYQAVEISDLRPQLAICHFKNEA
                     NLLGAAIDFYQEHKEA"
     gene            15996..16946
                     /locus_tag="VB649_000012"
     CDS             15996..16946
                     /locus_tag="VB649_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP1669003.1"
                     /translation="MTRQTNKKTSFWKNVIKYRALLLMVLPGFIWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLANFKYLFASKDAWLITRNTIAYNVIFLLFNVFF
                     AIAFAIIMSELRNKRTVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLTGSG
                     ADPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRNITIPQLLPMMSILLIINIGNIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDIGMASAASLYQSVVGTSILLVTNAIVRRMDPDAALF"
     gene            16956..17882
                     /locus_tag="VB649_000013"
     CDS             16956..17882
                     /locus_tag="VB649_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEP1669004.1"
                     /translation="MEKKKKVEKVNVRTFDRKTNAIFNILIGLFAISCIIPFIFVIII
                     SFTDESYLINHGYSFFPDVWSTKAYQYIFQGAMSHRIMRSFGISVFITVVGTFINTTM
                     TSTYAYAISRPYFPYRRFFTVYALITMLFAPGMVANYLVVSNLLHLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGASEWMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSENLYPMQYLLMKIQSNLQALAQNAGMSAQMADSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            17963..19408
                     /locus_tag="VB649_000014"
     CDS             17963..19408
                     /locus_tag="VB649_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP1669005.1"
                     /translation="MKKWQKIVCVTGTVLAASSLAACESKSASKDSDVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATVDLQYIGWGDWDDKMSTIIASGENYDIAFANNYVVN
                     AQKGAFADLTTLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNIKSYADAENVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKTQPFA
                     VKIDEGKPTIINQYEDESFKNNLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAARKDIVSRPLTKPLKTTSQAQMANFVVSSVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKIGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESVT
                     DDMIAKRDQSIKDAKESPILGFTVDTKVIKTELSNISNVMNRYKASINTGTVDPDEAL
                     PKLLADLKGAGWDKVQKEVQKQLDNFVAKDK"
     gene            19714..20319
                     /locus_tag="VB649_000015"
     CDS             19714..20319
                     /locus_tag="VB649_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEP1669006.1"
                     /translation="MNGIEKTCFLIWKMIQLTLIFHLLSLAGLIVFGVGPAWQTIVTL
                     FLKTPQEENHYSLKRAVQLWKSYFKEANLRFGLFALTFLFLTFNLHWAVQFPSLFWFT
                     VSFLIVIAMVWLTMTYLYMVFYAVSYEINLWNNMKLAFISVFLSFKSFLLMLSVLLGI
                     ILVTWQYKGLYLFLTFGALVFCLDFVTKANRRLVDGVIDEC"
     gene            20309..22033
                     /locus_tag="VB649_000016"
     CDS             20309..22033
                     /locus_tag="VB649_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1669007.1"
                     /translation="MSVKTLGRYVTNHFKQGFLINRLMKLYSLLIVSFFTLAAIGLSS
                     YSISSTYKRVDAEAQMRLEETLGRLQSQNDITLWVLDQLVGRSEDYHNLYQYMTLTPN
                     QYFSNVFEDWEKGKDTVLFSEEVRRLFDLYPDVTSMTLLLEDSSAYLYADRVIKTGRL
                     LYSKPEKVTGNVLVRSIRNPESGDVTGRLYLTFDKPPTLVETQQDHYLATFAFDYYGR
                     KLFHQGGRRFPHLEAEVKKAIKADRAADLSNLSKAYRMQYNRSGDLLAYVAVRKSYLL
                     AEAVRTVFVYGLVSLLLAWLLLQLLFRVFRNYIQQVSEITDTVEMVAAGDLSLTIDNS
                     HMELELYHISEAINQMLASIKAYIDEVYVLEVEQRDAQMRALQSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFASLLRNNISQDKMTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKIDESIADLAIPKFVIQPLVENYFVHGIDYSRNDNALSIKALDETDHLLIQVLDN
                     GRGISQERLADMEKRLQEHQTTGNSSIGLQNVYLRLFHHFRDRVSWSMAKEPNGGFII
                     QIRIRKDA"
     gene            22033..23517
                     /locus_tag="VB649_000017"
     CDS             22033..23517
                     /locus_tag="VB649_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1669008.1"
                     /translation="MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYL
                     TQYPVDVMISDVTMPGMTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGY
                     LLKPVDKAELQAKMKQFKDCLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQG
                     LPAAALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQAKA
                     FTYDLQKRFSRNMHQLILGETVDDWENVYESYNQVLKSLFYNCEVSPIRAKDKSKIEL
                     PESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQF
                     PILDKMTYLSMVKTIHDSQSIDRILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRK
                     EYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGDQ"
     gene            23447..26953
                     /locus_tag="VB649_000018"
     CDS             23447..26953
                     /locus_tag="VB649_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEP1669009.1"
                     /translation="MVYRQKSSEIVTRTITKPSRATSNVKQEIDMTSDSKEQTVTGYQ
                     YHYIDQEGRKQPFNQGWRFLMADVACAQDPSFDDSNWQVIHLPHDFSLKQPYTRNGEA
                     ESAYKLGGVGWYRHYLVLDEVLAGCHVAITFEGSYMETEIYVNGQFIGKHLNGYQEFT
                     YDISDVVTFGAENLLAVRVENKVPSSRWYSGSGLYREVSLSVLPQLHFVADQVAMTLA
                     DTAVQEKGQQKVDLRFALNQSIQTCHYQLSLCLWEQSHCSKDKKLLYQETEVPLADLA
                     FQRQYGLTLSLEELQLWSPDNPHLYDLELTLYYQGQVIDCFCLETGFRQLTFTANQGL
                     FVNGRAVKLKGVCLHHDQGGLGACAYEDALARQLVLLKDMGANTIRSTHNPSSPKLRQ
                     LANRLGFFVIEEAFDTWTYAKNGNVNDFSNYFHQTIGTENASYLQRVRSPETSWAQYS
                     IEAMVWSAKNDPSVLMWSIGNELMEGFSADVSHYPELTRQMCQWIAAIDTSRPITFGD
                     NKLKEADFCWHEEVSQMATLLSQLDHPQGLIGLNYANGKDYDKLHEEHSDWLLYGSET
                     ASAITSRAYYKETKKVLDSGYHLTSYDHAKVDWGAFASQAWYDTITRDFVAGECVWTG
                     FDYLGEPTPWNKIDSGVVGLWPSPKNAYFGILDTAGFPKDSYYFYQSQWAQGQTTLHL
                     LPVWQKDQLCFDEQGLVEVVVYSNAASVQLMFEDEQGNLTDYGRKAFHTYSMPTGHTY
                     QLYQGADAAKNPHENLYLTWRVPYQKGLLRAVAYDISGKSIPKTSGRSQVRTYGSVAK
                     LSWKAFEAPIDAPWELLYLDLSLLDSQGELVSHAQDWLKVQVEGPARLLALDNGNPTD
                     HTPYQEPLRQAYGGKLLAILALTGEAGHIKVTAKASQQLSSVFQTQVACRAPKEHLVT
                     LPLEKYQFKKSRLTSQQEIGQSCLKTTQFLSVLENKDTQQKAGKASTPHILITSYQHY
                     LPLPLQVCSQAFDFKKGDDIFLPQWLQVKDAQGSFVKKAFPMTWYLKEKIFAKPILVT
                     GYVSCFGQSIPVEARLNLAQASKRRHQDLSLVAKQSLAASQKRLTYCYQYDTVQAIGA
                     ISLQNHTGTSLSVSVAISYGSQSSIKQETLMLADSHLSQLEEVIFFDDILTVLYLAVT
                     LEVIEGPDLTEDSIQIGLWDLA"
     gene            27091..27969
                     /locus_tag="VB649_000019"
     CDS             27091..27969
                     /locus_tag="VB649_000019"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEP1669010.1"
                     /translation="MSERLSGHTLLVSLLATPIRHSLSPKMHNEAYAKLGLDYAYLAF
                     EVGTEQLADAVQGIRALGIRGSNVSMPNKEAILPLLDDLSPAAELVGAVNTVVNKDGK
                     GHLVGHITDGIGALRALADEGVSVKNKIITLAGVGGAGKAIAVQLAFDGAKEVRLFNR
                     QATRLSSVQKLVTKLNQLTRTKVTLQDLEDQTAFKEAIRESHLFIDATSVGMKPLENL
                     SLITDPELIRPDLVVFDIVYSPAETKLLAFARQHGAQKVINGLGMVLYQGAEAFKLIT
                     GQDMPVDAIKPLLGDE"
     gene            28204..28959
                     /locus_tag="VB649_000020"
     CDS             28204..28959
                     /locus_tag="VB649_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEP1669011.1"
                     /translation="MVTKEVGHDFLARLGKKRLRPGGVEATNWLIEQGQFSQDCHVLE
                     VACNRCTTAIELAKTFGCKIDAVDLNPKVVKEAQERVAVEGLTRHITVSQANALSLPF
                     PDNHFDIVINEAMLTMLNAQAKEKALNEYWRVLKPGGRLLTHDVAYEDPKTRQVLDEL
                     RQTIHVNVAPLSLTGWQALYQEHGFSQVTYHHGKMSLMTPRGMIKDEGLMNTLNIMRR
                     GLKKENRQQFLKMRRFFTRTGKNLCYIAVKSVK"
     gene            29012..29350
                     /locus_tag="VB649_000021"
     CDS             29012..29350
                     /locus_tag="VB649_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEP1669012.1"
                     /translation="MSYINNIEHAKVLDLTQEVMIEQDQMLSRTLVQRQDLGITVFSL
                     DKGQEIGRHSSPGDAMVTILSGLAEITIDQETYRVAEGQTIVMPAGIPHALYAVEAFQ
                     MLLVVVKPEA"
     gene            29352..29657
                     /locus_tag="VB649_000022"
     CDS             29352..29657
                     /locus_tag="VB649_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEP1669013.1"
                     /translation="MIENLSQLVQYHDHQVASRSLNRLLGLSQSIVLYAMAQGESISQ
                     ETSPRDKVILVLEGQLIFDLEDQKQVLTQESLIAIPAQKVHHLEAKTDCKLLQVLLD"
     gene            complement(30092..31165)
                     /locus_tag="VB649_000023"
     CDS             complement(30092..31165)
                     /locus_tag="VB649_000023"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEP1669014.1"
                     /translation="MPQTLHVHSRVKDYDILFTDHVLKTLADCLGERKQRKLLFITDQ
                     TVYHLYQTLFEEFAQQYNAFVHVCPPGGQSKSVERVSAIYDQLIAENFSKKDMIVTIG
                     GGVVGDLGGFVAATYYRGIPYIQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPE
                     AIIISTTFLETLPQREFSCGISEMLKIGFIHDKPLFQQLRDFQKETDKQGLERLIYQS
                     ISNKKRIVEQDEFENGLRISLNFGHTLGHAIESLCHHDFYHHGEAIAIGMVVDAKLAV
                     SKGLLPKEDLDSLLQVFERYQLPTTLERADVSATSLFDVFKTDKKNSEQHIIFILPTE
                     TGFTTLAINKDDHQFVEKLDSLL"
     gene            complement(31221..31973)
                     /locus_tag="VB649_000024"
     CDS             complement(31221..31973)
                     /locus_tag="VB649_000024"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEP1669015.1"
                     /translation="MIDIMSDFQNKTCSKNNFIVGPCSIESYDHIRLAASSAKKLGYN
                     YFRGGAYKPRTSAASFQGLGLQGIRYLHEVCQEFGLLSVSEIMSERQLEEAYDYLDVI
                     QVGARNMQNFEFLKTLSHIDKPILFKRGLMATIEEYLGALSYLQDTGKSNIILCERGV
                     RGYDVETRNMLDIMAVPIIQQKTDLPIIVDVSHSTGRRDLLLPAAKIAKAVGANGIMM
                     EVHPDPDHALSDAAQQIDYKQLEQLGQELWQD"
     gene            complement(32215..32285)
                     /locus_tag="VB649_000025"
     tRNA            complement(32215..32285)
                     /locus_tag="VB649_000025"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32251..32253),aa:Thr,seq:ggt)
     gene            32452..32706
                     /locus_tag="VB649_000026"
     CDS             32452..32706
                     /locus_tag="VB649_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEP1669016.1"
                     /translation="MSYEKEFLKDFEDWVKTQIQVNQLAMATSQEVAQEDGDERAKDA
                     FIRYESKLDAYEFLLGKFDNYKNGKAFHDIPDELFGARHY"
     gene            32727..33122
                     /locus_tag="VB649_000027"
     CDS             32727..33122
                     /locus_tag="VB649_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEP1669017.1"
                     /translation="MAKQKNRKKALKLEMKRNGLLKKAGQVFDKAVESVETAVDKTIS
                     AGKNLVEKGSQTVENLTASKERLTLDEFAGQPVVAGIRSDLVETLYAEGIHSAQAFKE
                     WTEKDLLALKGIGPATVKKLVENGASFKK"
     gene            33398..33988
                     /locus_tag="VB649_000028"
     CDS             33398..33988
                     /locus_tag="VB649_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP1669018.1"
                     /translation="MVKMLLEVYNRKTLLKVETERLLLRQRKLEDAEAIFAFAKLAEV
                     SYPAGFPPVKSLADEITYLQDIYPANLEKEGLPSSYGITLKGDDKVIGSIDFNHRRAD
                     DVFEIGYLLHPDYWGQGIVPEAAAALIEIGFTLIDLHKIELGCYDYNKQSQAVARKLG
                     FTLEANARDRKDVQGRRCGDMRFGLLRSEWEEQKQK"
     gene            33985..34499
                     /locus_tag="VB649_000029"
                     /pseudo
     CDS             33985..34499
                     /locus_tag="VB649_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
     gene            34501..37149
                     /locus_tag="VB649_000030"
     CDS             34501..37149
                     /locus_tag="VB649_000030"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEP1669019.1"
                     /translation="MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPP
                     PNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGQGI
                     TRYDLGREKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFV
                     DLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATT
                     RPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITP
                     AHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVN
                     IEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTF
                     LQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSA
                     LWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVLI
                     HGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDAS
                     WNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVT
                     ENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKIL
                     RLLHPIMPFVTEEIYAQYAQGSIVTAAYPTVTPAFENEAAHKGVESLKDLIRAVRNAR
                     AEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSI
                     ITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKE
                     KDKQADYQAKYDATQERIAEMKKIKS"
     gene            37302..39710
                     /gene="cas3"
                     /locus_tag="VB649_000031"
     CDS             37302..39710
                     /gene="cas3"
                     /locus_tag="VB649_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
                     /protein_id="HEP1669020.1"
                     /translation="MRMILAHYDCKKDKKQSLDEHLWHVACSSRQEASIIGQGDVLFL
                     IGLYHDLGKADRTFQDKLLNNPNRHVDHSYAGAKYLCSIIGPHLKNRGVDKNERMTFN
                     EMVGYVISAHHGMYDLCYYFDDAEYYGFNKFKNRINRDLDGYHYHEDIKGYALKLEKK
                     LCDYGYKDLRELIDKAFDNYQQAMSSLNWQDKSEWDYYQSCMVRLYLSLLKNADILDT
                     VNAYGLKISPMDKTERSFLKHSYLAAIEQKYASFGQPNNQLNTIRTEIAERVKERGKR
                     DSKGIYRLDLPTGAGKTNLSMRYAFHQLVHHDKSRFFYITPFLSVLEQNASEIRKVTG
                     DLGVLEHHSNVVKQANEDDDDKDSLLSAYLSDSWDSQVVLTSMVQFFQTLFKTKSANL
                     RRFSSLINSVVILDEVQSLPIEVTTLFNLTMNFLNKVMDTTIVLCTATQPAYDSSEID
                     HRICYGGNLGELAEIVELTIEERQIFSRTELRKFDDSDQKVHLTDVINLILGEENSVL
                     AIFNTKKTVHNCYTMLKDMTDRPVYQLSTNMCAQHRLDLIAKIKTELQNNIPIICIST
                     QLIEAGVDVDFHRVIRSYSGIDSIVQAAGRCNREGKRDKGQVTLVNLTNEEENISRLT
                     EIKAKKEATESILHKIGSPIDISTLNRDFFEYYYANNQGLMDYPLEDNLSIYDYLSLN
                     IYQTANKKFKGKLKQAFKTAGAKMNLINNDMIGILVSYGEAEKKLAYLEELGVSHFLS
                     AKDYQTIKSLLKELQPFTVNVRENDPLLDATKSFLNGQVLVLTSEYYDTERGVKYDSA
                     NFYF"
     gene            39843..40571
                     /gene="cas5c"
                     /locus_tag="VB649_000032"
     CDS             39843..40571
                     /gene="cas5c"
                     /locus_tag="VB649_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas5"
                     /protein_id="HEP1669021.1"
                     /translation="MYRSRDFYVRVSGQRALFTNPATKGGSERSSYSVPTRQALNGIV
                     DAIYYKPTFTNIVTEVKVINQIQTELQGVRALLHDYSADLSYVSYLSDVVYLIKFHFV
                     WNEDRKDLNSDRLPAKHEAIMERSIRKGGRRDVFLGTRECLGLVDDISQEEYETTVSY
                     YNGVNIDLGIMFHSFAYPKDKKTPLKSYFTKTVMKNGVITFKAQSECDIVNTLSSYAF
                     KAPEEIKSVNDECMEYDAMEKGEN"
     gene            40571..42466
                     /gene="cas8c"
                     /locus_tag="VB649_000033"
     CDS             40571..42466
                     /gene="cas8c"
                     /locus_tag="VB649_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas8c/Csd1"
                     /protein_id="HEP1669022.1"
                     /translation="MDFFTSLLKTYEKAELADLVDHQKRSNEPVLLPIYHTSLKSNGK
                     NIISVKLDKDGQFHKAEFMADKQMIIFPVTADSVARSGSHPAPHPLVDKFAYYSAEMG
                     QTQYDSFHKQLNNWIDYCEEGDVKKFLTFVQQFILKPEFLTLILDSLIGPDYQHNQLK
                     VTFCDATGKEKLIDLSACFLEFSIDQFQGFKNESVSTFKALHQSYISFVEAKRENLGI
                     CNISGREEQLTDKHRGLMGNAKIISVSNKREAYKGRFREREDVFSVGYETSEKIHLML
                     KYLLGNKNTSTWLGSSQYLINWFSDDLTNDSRLDIVSPIFDDGLEEDDDDDTPPVITL
                     ATEDNKRIGKSFIKGQKLFANDATYYVAILNKTSNGRIALKYFRQLQASQLLTNLNKW
                     QETYSWESRSKFGKSRLRTPTFHDILNVSYGVDRDRFLELDNDNFKSDQIQKLVASLI
                     DGKPMPQSIVKKLGNNVKERHRYRKHWYQVEQVCLAILHKQNGEEFSPMLDHTNQNRS
                     YLFGRLLAIFELIETLRYGLDGNNNDRITNAERYWTAYTGQPTKLMMLLENKIKPYEE
                     PLKLNRRGSWMKLEKEKEEILELLNPLLETETMEKPLDYRFIFGYYAEKNYYYTKQNT
                     EVTESEE"
     gene            42471..43319
                     /gene="cas7c"
                     /locus_tag="VB649_000034"
     CDS             42471..43319
                     /gene="cas7c"
                     /locus_tag="VB649_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated protein Cas7/Csd2"
                     /protein_id="HEP1669023.1"
                     /translation="MLEHKIDFMVTLEVKEANANGDPLNGNMPRTDAKGYGVMSDVSI
                     KRKIRNRLQDMGKSIFVQANERIEDDFRSLEKRFSQHFTAKTPDKEIEEKANALWFDV
                     RAFGQVFTYLKKSIGVRGPVSISMAKSLEPIVISSLQITRSTNGMEAKNNSGRSSDTM
                     GTKHFVDYGVYVLKGSINAYFAEKTVFSQEDAEAIKEVLVSLFENDASSARPEGSMRV
                     CEVFWFTHSSKLGNVSSARVFDLLEYNQSIEEKSTYDAYQIHLNQEKLAKYEAKGLTL
                     EILEGL"
     gene            43321..43995
                     /gene="cas4"
                     /locus_tag="VB649_000035"
     CDS             43321..43995
                     /gene="cas4"
                     /locus_tag="VB649_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HEP1669024.1"
                     /translation="MVYAEDDYLMLSGIQHFQFCKRQWALIHIEQQWLDNEATAHGQV
                     LHTKADNPYIKEKRKELLVSRAMPISSAELGLSGIMDVVEFYKDDQGVSLRGKRGKWL
                     PKVVEYKRGKPKKDTRDIVQLVAQTMCLEETLDCDINEGCLYYHSVNQRVIVPMTSAL
                     RQEVKELAAEMHEVYQSQMLPKAAYFKNCQLCSLVDICKPRLSKKTRSVSRYINEAMT
                     SEEMDL"
     gene            43992..45017
                     /gene="cas1c"
                     /locus_tag="VB649_000036"
     CDS             43992..45017
                     /gene="cas1c"
                     /locus_tag="VB649_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-C CRISPR-associated endonuclease Cas1"
                     /protein_id="HEP1669025.1"
                     /translation="MKKLLNTLYLTQEDFYVTKEGDNIVIKQEGKVLKRFPFRIIDGI
                     VCFSYLGVSPALVKLCTENQINLSFHTPQGRFCGRYIGSTNGNVLLRREHYRLSDREE
                     SLEYAKRFILAKISNSRKYLLRFKRDHRQQIDTKLFEAVNDELIWALEMVQAADNKDS
                     LRGIEGQAANQYFRIFNDLVLTDKKTFYFQGRSKRPPLDCVNALLSFGYSLLTFECQS
                     ALEAVGLDSYVGFFHTDRPGRASLALDLVEEFRSYIVDRFVFSLINKGQLQKKHFEVK
                     ENGSILLTENGRAIFIDLWQKRKHTEVEHPFTKEKVKLMLLPYVQAQLLAKAIRGDLE
                     SYPPFMV"
     gene            45028..45318
                     /gene="cas2"
                     /locus_tag="VB649_000037"
     CDS             45028..45318
                     /gene="cas2"
                     /locus_tag="VB649_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002280569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEP1669026.1"
                     /translation="MMVLVTYDVNTETPAGRKRLRHVAKLCVDYGQRVQNSVFECSVT
                     PAEFVDIKHRLTQIDEKTDSIRFYLLGKNWQRRVETLGRSDSYDPDKGVLLL"
     repeat_region   45466..45630
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=45467..45497
                     /rpt_unit_seq="gtctcacccttcatgggtgagtggattgaaa"
     gene            45791..46501
                     /gene="ccdA2"
                     /locus_tag="VB649_000038"
     CDS             45791..46501
                     /gene="ccdA2"
                     /locus_tag="VB649_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEP1669027.1"
                     /translation="MTLSLVLMVSVFGAGLLSFFSPCIFPVLPVYLGILLDADDSKTI
                     TIFGKKLYWYGIVKTLAFIFGLSTIFVILGYGAGFLGNILYAVWFRYLLGAVVIILGI
                     HQMGLITIKSLQFQKSLTFHNNKNRNGLFNAFILGLTFSFGWTPCVGPVLSSVLALVA
                     SGGNGAWQGGVLMIIYTLGLGIPFLLISFASGIVLKQFNKLKPHILLLKKVGGVLIIV
                     MGILLMTGTLNNLAQLFG"
     gene            46514..47137
                     /locus_tag="VB649_000039"
     CDS             46514..47137
                     /locus_tag="VB649_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEP1669028.1"
                     /translation="MKKGLLVTTGLACLGLLTACSTQDNMAKKEITQDKMSMAAKKKD
                     KMSTSKDKSMMADKSSDKKMTNDGPMAPDFELKGIDGKTYRLSEFKGKKVYLKFWASW
                     CSICLSTLADTEDLAKMSDKDYVVLTVVSPGHQGEKSEADFKKWFQGTDYKDLPVLLD
                     PDGKLLEAYGVRSYPTEVFIGSDGVLAKKHIGYAKKSDIKKTLKGIH"
     gene            47180..48286
                     /gene="msrB"
                     /locus_tag="VB649_000040"
     CDS             47180..48286
                     /gene="msrB"
                     /locus_tag="VB649_000040"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEP1669029.1"
                     /translation="MEHKWKLWLFIVGVVLLIGGASVLIQKGQAKAFSQGKPQLPAKK
                     VKSTKVDPNAPVDQKMIYLAGGCFWGVEEYFSQVDGVLDAVSGYANGRGDTTNYQLIH
                     QTGHAETVEVAYDANRISLKELLLHFFRIIDPTSLNKQGNDRGSQYRTGIYYTDKAEL
                     AIIDEVFKEKAKDYKKKIVVEKAPLKHFIKAEDYHQDYLKKNPNGYCHIDINQATYPV
                     IDESKYPKPSATEIKAKLSADEYRVTQKNETEKAFSNRYWDSFDAGIYVDVVTGEPLF
                     SSKDKFESGCGWPSFSRPISPDVVRYKEDKSFNMTRTEVRSRSGNSHLGHVFTDGPKD
                     QGGLRYCINSLSITFIPKADMEAKGYGYLLSSVE"
     gene            48374..49114
                     /locus_tag="VB649_000041"
     CDS             48374..49114
                     /locus_tag="VB649_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEP1669030.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLF
                     QKEPYDIVLTDINMPKLNGIQLAELIKEHAPQTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKADVEDMLGKLRKKLELSKKTETIQKLVEQPQKEVSAIAMAIHERLADSDLT
                     LKSLAQQFGFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVG
                     FEDMNYFSQRFKQLVGVTPSQYKKGGQA"
     gene            49111..50844
                     /locus_tag="VB649_000042"
     CDS             49111..50844
                     /locus_tag="VB649_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1669031.1"
                     /translation="MKRYPLLVQLISYVFVIVIALITMLGLLYYQTSSRNIRQLIERD
                     TRQSIRQSSQFIDAYIKPLKETTSVLAKNTEIQAFASQIHQENDKQVLQLMKMVLATN
                     SDLQAAVLVTKDGRTVSTNSQLTMKTSSDMMAEPWYKAAIDRQSMPILTPARQLSLSS
                     KKEWVVSVTQEVVDAAGHNLGVLRLDIAYPTIKASLDQLQLGRQGFAFIVNDKHEFVY
                     HPKKSVYSSSKEMAAMKPYLAIQNGYTKDKTSFVYQKLIPNSQWTLVGVASLDQLHRV
                     QRQIFWSFLGTGLLACLICGFATVLALRRWIRPIQQLQQVILAIQKGDRQLRAQETGS
                     PELTDLAQQFNALLDQIDSLMVAVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSKRVVAVTKSLAKYFRLALNQGNEYIRLADELDHVSQYLFIQKQRYGDKLSYE
                     VQGLDVYADFVIPKLILQPLVENAIYHGIKEVDRKGMIKVTVSDTAQHLVLTVWDNGK
                     GIEDSSLTNSQSLLTRGGVGLKNVDQRLKLHYGEGYHMTIHSQSDQFTEIQLSLPKMH
                     ELMADNTQENE"
     gene            50917..51996
                     /locus_tag="VB649_000043"
     CDS             50917..51996
                     /locus_tag="VB649_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEP1669032.1"
                     /translation="MSLATDYFSRQTPIVEKLIAYGFEKRDNGYFYNEQFMEEEFEAQ
                     LRIDEAGNIWDRVIDCDLEEDYLPLQQAACQGTYSGQVRAAYLELLERLSVACFEATP
                     FQSMQANRLAKHITKEWSDPMDYPFEKHPDLATYRVGGKWYAMIFSLLADKLDQIPER
                     LVGQICEVMTVKVNPKNLPQLLQQEGIYPAYHMSKNNWVSVVLDDKVTDDKLWTLVTQ
                     SRQLVNPKGLSNPNGPDYWVIPANLKYYDIDAEFAANDVILWTQKAGIAVGDYVLIYM
                     TAPVKSIRYTCQVLETNISNQGYRKNSNIDKLMRLRKCQQYEDGLLSFDLMKEHGVAA
                     VRGPRRLSPQLIAFFKKKEYLKGNN"
     gene            52019..52735
                     /locus_tag="VB649_000044"
     CDS             52019..52735
                     /locus_tag="VB649_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEP1669033.1"
                     /translation="MVQFVADQSFWELFPDAKLGVVLLKDVQNQGESPEDVKQLLADS
                     HELAKAYLTADNFSDNQVVQVYRKAYQHFKTKKGARSSIEALLKRVSNGQSIPSINPL
                     VDIYNAASLRFGLPVGAEDSDSFIGDLRLTITDGGDDFYLIGDADNNPTLPNELCYKD
                     DIGAVCRCLNWRDGERTMVIEHTQNAFLIIEALDQEGQNRLQEALKFIEGSAKMYLHA
                     ITSVHVLDKDNPHVPLFTEN"
     gene            complement(52901..53374)
                     /locus_tag="VB649_000045"
     CDS             complement(52901..53374)
                     /locus_tag="VB649_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP1669034.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSR
                     DMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGL
                     AQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK"
     gene            53516..54196
                     /locus_tag="VB649_000046"
     CDS             53516..54196
                     /locus_tag="VB649_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEP1669035.1"
                     /translation="MIRREDYQYLRKLNDFRYFSIEQFDKIVGQMEFRKAKKDHILFF
                     EGDKRDKLFLVTSGYFKVEQSDQSGTFMYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPVDLFEDYSLENRLQMKHLYSKMSKLLELHELRVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQISGTTRETVSHVLRDLKKQELITIKGKYLTYLDK
                     DYFLQYTK"
     gene            54470..55705
                     /gene="arcA"
                     /locus_tag="VB649_000047"
     CDS             54470..55705
                     /gene="arcA"
                     /locus_tag="VB649_000047"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEP1669036.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            55744..56097
                     /locus_tag="VB649_000048"
                     /pseudo
     CDS             55744..56097
                     /locus_tag="VB649_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407703.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            56137..57150
                     /gene="argF"
                     /locus_tag="VB649_000049"
     CDS             56137..57150
                     /gene="argF"
                     /locus_tag="VB649_000049"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEP1669037.1"
                     /translation="MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEDDIVTLAEGYAKESGARILITEDA
                     DEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            57320..58813
                     /locus_tag="VB649_000050"
     CDS             57320..58813
                     /locus_tag="VB649_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEP1669038.1"
                     /translation="MTEEKKRGFRIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKGGG
                     VISGTYKTVASNPQGLFDILMAPVRGMLGVEGTDGAIQVSFFILMVGGFLGVVNKTGA
                     LDTGIASVVRKNKGREKMLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRVIQWVILVGMSIWFV
                     YNYASKIEEDPSKSLVADKEEEHKELFQLQNSGEDLNKRQRNVLTIFTLTFVIMILSL
                     IPWEDFGIKFFTNINTWLTTMPILGGVIGKTMGAFGTWYFPEITMLFIMMGVLVAIVY
                     RMSEEDFFSSFLTGAGEFLGVAMICAIARGIQVIMNGGMITATILHLGETSLSGLSSQ
                     VFVILAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRVDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            58830..60161
                     /locus_tag="VB649_000051"
     CDS             58830..60161
                     /locus_tag="VB649_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEP1669039.1"
                     /translation="MESYITPKHQEACVAAIKQIVSYPSVCHEGENGTPFGQAIQDVL
                     EATLDLCQGLGFHTYIDPKGYYGYAELGDQKEVLAILCHLDVVPEGDRQLWKTDPFDC
                     VEADGCLFGRGTQDDKGPTMMALFATKALIDAGVTFNKRIRFIFGTDEETLWRCMNRY
                     NDVEEQATFGFAPDSSFPLTYAEKGLLQAKLVGKGSDKLSLEIGQAYNVVPARASYQG
                     DKLEALQKELDKLGFEYVVKEGELTVYGLAQHAKDAPDGINAMIRLAKALVVLEPNKT
                     LDFLANVIDEDGRALNIFGRIEDEPSGKLSFNAAGLTLTKDKAEIRLDIRIPVLADKE
                     KLVQQLSQKAQEYGLTYEEFDYLAPLYVPLDSELVTTLLSVYRKKTGDQSPAQSSGGA
                     TFARTMKNCVAFGALFPDAAQTEHQENEHIVLAEAYRAMDIYAEAIYRLTR"
     gene            60181..61131
                     /gene="arcC"
                     /locus_tag="VB649_000052"
     CDS             60181..61131
                     /gene="arcC"
                     /locus_tag="VB649_000052"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEP1669040.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALISTSKSLVKLIKEGH
                     EVIVTHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNAFDNELQAQ
                     GIQKEVAAVVTQVIVDAKDPAFENPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPVGIKEANVIRSLVDSGVVVVSAGGGGVPVVEDATSKSLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYINFNKPDQAKLEEVTVSQMKEYITQDQFAPGSMLP
                     KVEAAIAFVENKPNAKAIITSLDNIDNVLSANAGTQIIAG"
     gene            61444..62436
                     /locus_tag="VB649_000053"
     CDS             61444..62436
                     /locus_tag="VB649_000053"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEP1669041.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTTETENGYNGLNGDILVRNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAF
                     DWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKQHIGEVQTSVWPQEVRDSYDNIL"
     gene            62559..63098
                     /gene="rsmD"
                     /locus_tag="VB649_000054"
     CDS             62559..63098
                     /gene="rsmD"
                     /locus_tag="VB649_000054"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEP1669042.1"
                     /translation="MRVVSGEFGGRPLKTLDGKITRPTSDKVRGAIFNMIGPYFNGGR
                     VLDLFAGSGGLAIEAVSRGMSAAVLVEKNRKAQAIIQDNIIMTKAENRFTLLKMEAER
                     AIDCLTGRFDLVFLDPPYAKETIVATIEALAAKNLLSEQVMVVCETDKTVLLPKEIAT
                     LGIWKEKIYGISKVTVYVN"
     gene            63088..63579
                     /gene="coaD"
                     /locus_tag="VB649_000055"
     CDS             63088..63579
                     /gene="coaD"
                     /locus_tag="VB649_000055"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEP1669043.1"
                     /translation="MLTKVGLYTGSFDPVTNGHLDIVKRASGLFDQIYVGIFDNPTKK
                     SYFKLEVRKAMLTQALADFTNVIVVTSHERLAIDVAKELRVTHLIRGLRNATDFEYEE
                     NLEYFNHLLAPNIETVYLISRNKWQALSSSRVRELIHFQSSLEGLVPQSVIAQVEKMN
                     EKT"
     gene            63566..64603
                     /locus_tag="VB649_000056"
     CDS             63566..64603
                     /locus_tag="VB649_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEP1669044.1"
                     /translation="MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTV
                     LQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTPFTEISTAEDTTGGYSDADFLRI
                     NQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
                     QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSV
                     NSEDTVIFSTKGVGGPSAGLMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGG
                     AGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRAAKRLKTKMKIVPVT
                     TVQEALVYLRK"
     gene            65014..65991
                     /locus_tag="VB649_000057"
     CDS             65014..65991
                     /locus_tag="VB649_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP1669045.1"
                     /translation="MVTIKQVAEEAGVSRSTVSRYISQKGYVSDDARHKIKAAIAKLH
                     YTPNVLAQSLKTKKNQLVGLLLPDISNPFFPRLARGAEEYLKEKGYRVMLGNISDSEA
                     LEEEYVHVLLQSNAAGIITTHDFTKRYPTLAIPVVVVDRVDQETQYGVFSDNRAGGLL
                     AAQTVWQAGAKEVLLIRGPLDNAENINERFEASFSYLQKQDVTMYVCDSQNFDFESIQ
                     LEASYNLKCYPTIDSIIAPSDIHAIAYIHELHSQGKKIPQDVQIIGYDDILMSQFIYP
                     SLSTIHQSSYLMGRYAAELVYTIASQLTVKANRIKLPVHYVERETIRKR"
     gene            66415..67059
                     /locus_tag="VB649_000058"
     CDS             66415..67059
                     /locus_tag="VB649_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1027 domain-containing protein"
                     /protein_id="HEP1669046.1"
                     /translation="MDFSERCQMKKEISPEMYNYNKFPGPKFIHFEEQVKAEGIDLLL
                     LEDVKNAFDTTSFGQRYTEVLLKYDYIVGDWGNEQLRLKGFYKDSDDIKKTNRISRLE
                     DYIKEFCNFGCAYFVLENLHPQDIKFEEERQPRRKKSPKSKSNRRKPNYSNQQPATPK
                     SKSKRISKEKQPENQAFTSQKRRSNTKHKEKSKRNQTSQLNTKISHFIIRKKDK"
     gene            67063..68142
                     /gene="rlmN"
                     /locus_tag="VB649_000059"
     CDS             67063..68142
                     /gene="rlmN"
                     /locus_tag="VB649_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEP1669047.1"
                     /translation="MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEE
                     MTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVM
                     GIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANAGVQVNLAVS
                     LHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQE
                     LADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSKTMKKDREKVTATK"
     gene            complement(68224..68850)
                     /locus_tag="VB649_000060"
     CDS             complement(68224..68850)
                     /locus_tag="VB649_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEP1669048.1"
                     /translation="MIAFFSICSGILLTHLFYCLLLYFPDNGQEQLSKQTVIVCDQLT
                     FAKRVFRQFQNHFITSQKIFFSLEISLIIILWASMVHWVSASYCYLLLFSLLFSLFDW
                     RSQEYPFILWLFSFVSLLLFYSINYLSLILLLLGLLAHLRPFSIGAGDFFYLASLALV
                     LDLMSLIWLIQLASLAGITACLLLGIKRIPFIPYLSFGLFWIVLLEHF"
     gene            69078..69605
                     /locus_tag="VB649_000061"
     CDS             69078..69605
                     /locus_tag="VB649_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEP1669049.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDSLNANLDEMSERLITIGGAPYSTLAEFSKHSK
                     LDEAKGTYDKTVAQHLARLVEVYLYLSSLYQVGLDITDEEGDAGTNDLFTAAKTEAEK
                     TIWMLQAERGQGPAL"
     gene            69747..69950
                     /locus_tag="VB649_000062"
     CDS             69747..69950
                     /locus_tag="VB649_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEP1669050.1"
                     /translation="MKTLYDVQQLLKNFGIFVYLGKRLYDIEMMKIELQRLYDSGLLD
                     KRDYLNAELILRREHRLELEKEG"
     gene            69955..70926
                     /locus_tag="VB649_000063"
     CDS             69955..70926
                     /locus_tag="VB649_000063"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEP1669051.1"
                     /translation="MSQKLLGIDLGGTTIKFGILTAAGEVQEKWAIETNILEGGKHIV
                     PDIIASIKHRLDLYGLSSADFVGIGMGSPGAVDRDTNTVTGAFNLNWKETQEVGSVVE
                     KELGIPFAIDNDANVAALGERWVGAGENNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPENGFACTCGSHGCLETVASATGVVKVARLLAEAYEGDSAIKAAIDNG
                     EGVTSKDIFMAAEAGDSFADSVVEKVGYYLGLASANISNILNPDSVVIGGGVSAAGEF
                     LRSRIEKYFVTFTFPQVRYSTKIKIAELGNDAGIIGAASLARQFITK"
     gene            70936..71325
                     /locus_tag="VB649_000064"
     CDS             70936..71325
                     /locus_tag="VB649_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEP1669052.1"
                     /translation="MSPITLILWLLLVGIVGYYTWNYFSFRKMAKQVDNETFKDVMRQ
                     GQLIDLREPAAFRAKHILGARNFPAQQFDAAIKGLRKDKPVLIYENMRPQYRVPAVKK
                     LKKAGFEDVYVLKDGIDYWDGKVKQTT"
     gene            71508..73349
                     /gene="typA"
                     /locus_tag="VB649_000065"
     CDS             71508..73349
                     /gene="typA"
                     /locus_tag="VB649_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEP1669053.1"
                     /translation="MTNLRNDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLIPIVVVNKIDKPSARPAEVVDEVLELFIELGADDEQ
                     LEFPVVYASAINGTSSLSDDPADQEHTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPILRIDEPTLQMTFLVNNSPFAGREGKWITSR
                     KVEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            73471..73722
                     /locus_tag="VB649_000066"
     CDS             73471..73722
                     /locus_tag="VB649_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEP1669054.1"
                     /translation="MFYLIMAVLIISYYLYMAPKSVRNTLGMIGLVGLVALFIVLAGL
                     SFIKIMQTPPEFFIGMGMVALGYFALKDVRKMTKKPRVK"
     gene            74078..75436
                     /locus_tag="VB649_000067"
     CDS             74078..75436
                     /locus_tag="VB649_000067"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEP1669055.1"
                     /translation="MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFD
                     QNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTE
                     VELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIA
                     GDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESD
                     YLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPG
                     SHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNI
                     LATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKA
                     EVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRG
                     DA"
     gene            75436..76518
                     /locus_tag="VB649_000068"
     CDS             75436..76518
                     /locus_tag="VB649_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEP1669056.1"
                     /translation="MPKKILFTGGGTVGHVTLNLILIPKFIKDGWEVHYIGDKNGIEH
                     TEIEKSGLDVTFHAIATGKLRRYFSWQNLADVFKVALGLLQSLFIVAKLRPQALFSKG
                     GFVSVPPVVAAKLLGKPVFIHESDRSMGLANKIAYKFATTMYTTFEQEDQLSKVKHLG
                     AVTKVFKDANQMPESTQLEAVKEYFSRDLKTLLFIGGSAGAHVFNQFISDHPELKQRY
                     NIINITGDPHLNELSSHLYRVDYVTDLYQPLIAMADLVVTRGGSNTLFELLAMAKLHL
                     IVPLGKEASRGDQLENATYFEKRGYAKQLQEPDLTLHNFDQAMADLFEHQADYEATML
                     ANKEIQSPDFFYDLLRADISSAIKEK"
     gene            76519..77667
                     /locus_tag="VB649_000069"
     CDS             76519..77667
                     /locus_tag="VB649_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HEP1669057.1"
                     /translation="MAKDKEKQSDDKLVLTEWQKRNIEFLKKKKQQAEEEKKLKEKLL
                     SDKKAQQQAQNASEAVELKTDEKTDSQEIESETTSKPKKTKKVRQPKEKSATQIAFQK
                     SLPVLLGALLLMAVSIFMITPYSKKKEFSVRGNHQTNLDELIKASKVKASDYWLTLLI
                     SPGQYERPILRTIPWVKSVHLSYHFPNHFLFNVIEFEIIAYAQVENGFQPILENGKRV
                     DKVRASELPKSFLILNLKDEKAIQQLVKQLTTLPKKLVKNIKSVSLANSKTTADLLLI
                     EMHDGNVVRVPQSQLTLKLPYYQKLKKNLENDSIVDMEVGIYTTTQEIENQPEVPLTP
                     EQNAADKEGDKPGEHQEQTDNDSETPANQSSPQQAPPSPETVLEQAHG"
     gene            77879..79243
                     /gene="ftsA"
                     /locus_tag="VB649_000070"
     CDS             77879..79243
                     /gene="ftsA"
                     /locus_tag="VB649_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEP1669058.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAATAIKTAVEQAEEKAGMTIEKVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKTILNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSLAIAEALKFNFGQAEISEASITETVKVD
                     VVGSEEPVEVTERYLSEIISARIRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEIAQEIFGVTVKLHVPNQVGIRNPMFSNVISLVEYVGMMSEVDVLAQTAVSGEELLR
                     RKPIDFSGQESYLPDYDDSRRPESTIGYEQQASQTAYDSQVPSDPKQKISERVRGIFG
                     SMFD"
     gene            79267..80586
                     /gene="ftsZ"
                     /locus_tag="VB649_000071"
     CDS             79267..80586
                     /gene="ftsZ"
                     /locus_tag="VB649_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEP1669059.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEILTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRGNFAIEGIEELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAQDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDTMKDDIRVTVVATGVRQEKAEQVSGFRQPRTFT
                     QTNAQQVAGAQYASDQAKQSVQPGFDRRSNFDFDMGESREIPSAQKVISNHNQNQGSA
                     FGNWDLRRDNISRPTEGELDNHLNMSTFSANDDSDDELETPPFFKNR"
     gene            80589..81260
                     /locus_tag="VB649_000072"
     CDS             80589..81260
                     /locus_tag="VB649_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEP1669060.1"
                     /translation="MDLLTNKKKIFETIRLSTEAANRTTDSVSVIAVTKYVDSTIAGQ
                     LIEAGIEHIAENRVDKFLEKYDALKYMPVKWHLIGTLQRRKVKEVINYVDYFHALDSV
                     RLALEINKRADHPVKCFLQVNISKEESKHGFNISEIDEAIEEIGKMEKIQLVGLMTMA
                     PANASKESIITIFRQANQLRKNLQLKKRKNMPFTELSMGMSNDYPIAIQEGSTFIRIG
                     RAFFH"
     gene            81272..81928
                     /locus_tag="VB649_000073"
     CDS             81272..81928
                     /locus_tag="VB649_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEP1669061.1"
                     /translation="MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRAS
                     SHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMS
                     TSSIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQA
                     RRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
                     "
     gene            81933..82187
                     /locus_tag="VB649_000074"
     CDS             81933..82187
                     /locus_tag="VB649_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEP1669062.1"
                     /translation="MILILSILLRLIKVYTYLLIAYALMSWFPGAYDSKIGRLISGIV
                     EPILKPFRAFNLQFAGLDFTIFVVIISLNFLAQVLVRVFI"
     gene            82187..82978
                     /locus_tag="VB649_000075"
     CDS             82187..82978
                     /locus_tag="VB649_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEP1669063.1"
                     /translation="MVSHSKIYQHFHQEEYPFIDRMSDMINRVEDYYLLEVTEFLNPR
                     EVMILKSLIALTDLKMFVSTDYYPSEYGRVIIAPGYYDLEQSDFQIALVEISYQAKFN
                     QLTHSQILGTLINELGVKRNLFGDVFVEMGYAQLMIKRELLDYFLGTITKIAKTSVKL
                     REVNFDQLIRSIDNSQTLDILVSSFRLDGVVATILKKSRTQVIALIEANKIKVNYRLA
                     NKASDNLVIGDMVSIRGHGRFTLLADNGVTKHGKQKITLSKMIHK"
     gene            82988..83746
                     /locus_tag="VB649_000076"
     CDS             82988..83746
                     /locus_tag="VB649_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEP1669064.1"
                     /translation="MALTTLEIKDKTFKTKFRGYCEEEVNEFLDIVVDDYEALVRKNR
                     DNEARIKDLEEKLSYFDEMKESLSQSVILAQETAEKVKATANAEATNLVSKATYDAQH
                     LLDESKAKANQMLRDATDEAKRVAIETEELKRQTRVFHQRLISSIESQLSLSNSPEWD
                     ELLQPTAIYLQNSDDAFKEVVKTVLNEDIPESDDSASFDATRQFTPEELEELQRRVDE
                     SNKELEAYQLDSQSDSTTEPEVNLSETQTFKLNI"
     gene            84019..86820
                     /locus_tag="VB649_000077"
     CDS             84019..86820
                     /locus_tag="VB649_000077"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEP1669065.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQAAWEQAELYKKRQELN
                     AGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFQAPYVPGWDTHGLPIE
                     QVLAKQGIKRKEMDLAEYLEMCRQYALSQVDKQRNDFKRLGVSADWENPYVTLDPQFE
                     ADQIRVFGAMAEKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GILDTNTYIVVWTTTPFTVTASRGLTVGPDMDYLVVKPAGSDRQYVVAEGLSDSLAGK
                     FGWESFETLASHKGADLEYIVTEHPWDTDVEELVILGDHVTLESGTGIVHTAPGFGED
                     DYNVGTKYKLEVAVTVDERGLMMENAGPDFHGQFYNKVTPIVIDKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQDILDEIEKTTFHPSWGETRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQENGSIIWWQKEAKDLLPEGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMEILGQVSETYRKIRNTLRFLIANTSDFNPATDTVAYADLGAVDKYMT
                     IVFNQLVATITDAYERYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLERRR
                     MQTVFYDILVKITKLLTPILPHTTEEIWSYLEHESEAFVQLTEMPVAETFSAQEDILE
                     AWSAFMTLRTQAQKALEEARNAKVIGKSLEAHLTIYASEEVKTLLTALDSDIALLLIV
                     SQLTIADLADAPADAVAFEGIAFMVEHAIGEVCERSRRIDPTTRMRSYNAFVCDHSAK
                     IIEENFPEAVAEGFEESGK"
     gene            complement(87085..87387)
                     /locus_tag="VB649_000078"
     CDS             complement(87085..87387)
                     /locus_tag="VB649_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEP1669066.1"
                     /translation="MRLINTTSSHPELIRNQLKNTDAYLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELDIIREFFLKRKIDPKIVIPGQSKTLHTNNLIEISFQTSV"
     gene            complement(87438..87893)
                     /locus_tag="VB649_000079"
     CDS             complement(87438..87893)
                     /locus_tag="VB649_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP1669067.1"
                     /translation="MMIPTFGHKNAHKDYVTRYGVYAIIPNHEQTKIILVQAPNGSWF
                     LPGGEIEAGEGQLQALERELIEELGFSATIGSYYGQADEYFYSRHRDTHFYHPAYLYE
                     VTAFQAVSKPLEDFNNLGWFSPIEAIAKLKRESHQWGVKEWQKKHHSTN"
     gene            complement(88021..90303)
                     /locus_tag="VB649_000080"
     CDS             complement(88021..90303)
                     /locus_tag="VB649_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP1669068.1"
                     /translation="MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSI
                     LNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLPNTPPTQAGQNGNGGGRYGGNYN
                     GQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
                     PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERM
                     QKLMEEIRNRKDVILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGELQLVGATTLN
                     EYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSPAAIEAAAHL
                     SNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYE
                     RAAYFRDQITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVN
                     LANDLKAHVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLA
                     IELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
                     EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAR
                     EGRTSSVLGELSNFFSPEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIH
                     LDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTEKQLRALMTNSE
                     NITIKAVKEGNSFLNEESLD"
     gene            90601..90831
                     /locus_tag="VB649_000081"
     CDS             90601..90831
                     /locus_tag="VB649_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEP1669069.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPEN
                     GPVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            90958..91644
                     /locus_tag="VB649_000082"
     CDS             90958..91644
                     /locus_tag="VB649_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP1669070.1"
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRS
                     HVKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNE
                     FITIIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVL
                     ERHMAQGGNH"
     gene            91644..92378
                     /locus_tag="VB649_000083"
     CDS             91644..92378
                     /locus_tag="VB649_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP1669071.1"
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVI
                     VEEGSPNQLFDLTKEERTKDFLSRVL"
     gene            92527..93936
                     /locus_tag="VB649_000084"
     CDS             92527..93936
                     /locus_tag="VB649_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HEP1669072.1"
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLH
                     SRNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGY
                     GRLRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKET
                     PIKVELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHA
                     NRDFPAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELAWRDFYNMVYV
                     AYPDQKTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRM
                     IVASFLTKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVT
                     QGKRFDPKGEFIKAYLPQLEHVPEKYLHEPWKMPKYLQESVSCIIGTDYPQPIVDHAK
                     QREQAIAKYEWAKEKAKIE"
     gene            94114..95808
                     /locus_tag="VB649_000085"
     CDS             94114..95808
                     /locus_tag="VB649_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEP1669073.1"
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEF
                     GTAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFA
                     ELTCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQ
                     EGSQILDDIADQIAQHMAALTQYQEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPN
                     PEVPKTFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYY
                     IFSQRFDLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVT
                     KQKNYLFGYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATF
                     GYYNERQIALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQN
                     CLKFYLDDGSWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIESACRTKINQVN"
     gene            96016..96870
                     /locus_tag="VB649_000086"
     CDS             96016..96870
                     /locus_tag="VB649_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEP1669074.1"
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDP
                     ASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPN
                     HINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKH
                     AVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQ
                     YIKDGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQ
                     SALRSTHK"
     gene            97023..98363
                     /locus_tag="VB649_000087"
     CDS             97023..98363
                     /locus_tag="VB649_000087"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEP1669075.1"
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDG
                     IGALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRF
                     PGVEILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESQLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQN
                     RSYQACLRRIKQRQEWVDKLSQSVIFKQPERLYDAYLQKIDRLSMTLMNTMKDRLSSA
                     KENKVQLDHALANSQLQTKIERYQDRVATAKRLLMANMASQYDSQLARFEKAQDALLS
                     LDASRIIARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVKDVKNENI"
     gene            98341..98556
                     /locus_tag="VB649_000088"
     CDS             98341..98556
                     /locus_tag="VB649_000088"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEP1669076.1"
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKE
                     LQKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            98556..99428
                     /locus_tag="VB649_000089"
     CDS             98556..99428
                     /locus_tag="VB649_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEP1669077.1"
                     /translation="MDKLARIDEAIRRYYKKTSNGVSEELIDAILYSVDSGGKRIRPL
                     ILLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGE
                     ATAILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQA
                     LSLPQLSLIHLNKTGKLLTFPFKAAALVTEQAITVRQQLEQAGMLIGHAFQIRDDILD
                     VTASFEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKP
                     QIITKLIEGLRLNA"
     gene            99421..100248
                     /locus_tag="VB649_000090"
     CDS             99421..100248
                     /locus_tag="VB649_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEP1669078.1"
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPG
                     DKIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQ
                     DGAKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFIS
                     LSLILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASD
                     YGFTVKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQKVVAKAHKEFEKHEKE"
     gene            100235..100705
                     /locus_tag="VB649_000091"
     CDS             100235..100705
                     /locus_tag="VB649_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP1669079.1"
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRD
                     MNEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVV
                     PGNSKLIKRYLLADFSKAIFSLIADDDSLLLIARSPSEADMIRQEILLWMQGIT"
     gene            100727..102388
                     /gene="recN"
                     /locus_tag="VB649_000092"
     CDS             100727..102388
                     /gene="recN"
                     /locus_tag="VB649_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEP1669080.1"
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     MLGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGR
                     SVSRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKEN
                     YQLIFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDR
                     LMNHKQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYY
                     ILEEVSKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEY
                     QLLTGDDLSSGDLESELKALEKQLVAAATNLSECRHQLAEQLEAEIKAELKELYMEKA
                     DFKVHFTTSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKE
                     DKTSIVFDEVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKES
                     KEESTVSKVRLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            102560..103492
                     /locus_tag="VB649_000093"
     CDS             102560..103492
                     /locus_tag="VB649_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP1669081.1"
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVE
                     KDVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFISQNETDKMFENLTDDRLLNEL
                     DESDEEDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLRSLS
                     DTALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAHYED
                     RKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYNRKLGMAVAKRKI
                     ALPQTGEEFSYYPALLGLMILGLTPIMIPKKINN"
     gene            103708..104559
                     /locus_tag="VB649_000094"
     CDS             103708..104559
                     /locus_tag="VB649_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP1669082.1"
                     /translation="MEKYMGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSD
                     NDLKEEGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTI
                     EASRQGAEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTE
                     LYIGVSTLENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLD
                     SYLTKNSHRPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            104552..105394
                     /locus_tag="VB649_000095"
     CDS             104552..105394
                     /locus_tag="VB649_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEP1669083.1"
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKE
                     QVAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQIL
                     DRMIKQKQIQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQI
                     IELARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPI
                     NDLLYKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEK
                     KIKR"
     gene            105372..105959
                     /locus_tag="VB649_000096"
     CDS             105372..105959
                     /locus_tag="VB649_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEP1669084.1"
                     /translation="MKKKSNVNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIA
                     KKPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYE
                     VPLYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSA
                     IVVNLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            106058..106333
                     /locus_tag="VB649_000097"
     CDS             106058..106333
                     /locus_tag="VB649_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEP1669085.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            106687..108549
                     /gene="cadA"
                     /locus_tag="VB649_000098"
     CDS             106687..108549
                     /gene="cadA"
                     /locus_tag="VB649_000098"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HEP1669086.1"
                     /translation="MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITA
                     FLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAGIIGYWLEGALLIFIFSLSNTLE
                     EMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
                     LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINL
                     VESAQEKKSKTATFIESLEDGYVKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTV
                     ASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVVMDKTGTLTQGKPSV
                     VNAHYLEDELLVNRLVKGAETASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFY
                     QGQEWRIGKKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKI
                     ESKRAIKSLHAMGIKTVMLTGDQERTANYVAQKLGIDEVVANCMPQDKVAKLAELKTK
                     YGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSIQLSRKM
                     KTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK"
     gene            complement(108849..109784)
                     /locus_tag="VB649_000099"
     CDS             complement(108849..109784)
                     /locus_tag="VB649_000099"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEP1669087.1"
                     /translation="MVSTATQIGHFSFDNCLMNAAGVYCMTKEELMEVEKSQAASFVT
                     KTGTLEVRPGNPEPRYADTRLGSINSMGLPNNGFRYYLDFVSDLAKTGQHKPHFLSVV
                     GLSPTETETILKAIMASDYEGLVELNLSCPNIPGKPQIAYDFETTDQLLENIFTYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLSFVNCVNSIGNGLVIEDEQVLIKPKNGFGGI
                     GGDYIKPTALANVHAFYKRLKPSIHIIGTGGIKTGRDAFEHILCGASMVQIGTALHQE
                     GPAIFERVTKELKTIMVEKGYQSLDDFRGNLRYKD"
     gene            110023..110718
                     /locus_tag="VB649_000100"
     CDS             110023..110718
                     /locus_tag="VB649_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEP1669088.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAM
                     PYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDE
                     KLNIVKEYYLGGE"
     gene            110825..111346
                     /locus_tag="VB649_000101"
     CDS             110825..111346
                     /locus_tag="VB649_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEP1669089.1"
                     /translation="MKAEDRRQKIIECLNSEQKAVSATRLGKLLGVSRQVIVGDIALL
                     RAQQIDIISTPKGYIMSTALYSHQFCARIVCQHNVEETKKELEIILAHQGIITTVEVE
                     HPIYGMITAPLNIKTHSDVTNFMSKLSQSKAELLSSLTEGLHSHLISCPSQEAFLAIK
                     HDLELAGILYKGI"
     gene            111507..112049
                     /locus_tag="VB649_000102"
     CDS             111507..112049
                     /locus_tag="VB649_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669090.1"
                     /translation="MTKKPTQLIAYTSILVAFAILIPIIMPLKLIIGPASFTLASHVP
                     LFLAIFMSIPVAILVALGTTLGFLLAGLPLIIVLRALSHLLFAILAAWWLSRKPQLMT
                     SAVKCFSFAFFINVIHGLAEFLVVYILTATTATSMSYFWSMLGLIGLGSLIHGILDFY
                     LALVLWRFLAKNLKLPTINA"
     gene            112173..112952
                     /locus_tag="VB649_000103"
     CDS             112173..112952
                     /locus_tag="VB649_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEP1669091.1"
                     /translation="MKTPEQILEATIHIGEHKVTKTFLAKSILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSIVGACAFPIGLIIILMAGGELITGNMMAVSAALLAKKIKFSE
                     LAKNWLIITLFNVIGAVFVAFVFGHFLGLTSAGIFKEEVIEVAHAKIAASPLQALVSG
                     IGCNWFVGLALWLCYGANDAAGKFLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     TWLDFATNFIFVYSGNIIGGAIFVSFLYFKVYYHPQKSKTQ"
     gene            113750..114346
                     /gene="recR"
                     /locus_tag="VB649_000104"
     CDS             113750..114346
                     /gene="recR"
                     /locus_tag="VB649_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEP1669092.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            114447..115493
                     /locus_tag="VB649_000105"
     CDS             114447..115493
                     /locus_tag="VB649_000105"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEP1669093.1"
                     /translation="MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFIT
                     QMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVE
                     TLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEV
                     GLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAF
                     KALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVT
                     LAQEIFDQRESHLI"
     gene            115692..117083
                     /locus_tag="VB649_000106"
     CDS             115692..117083
                     /locus_tag="VB649_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEP1669094.1"
                     /translation="MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLP
                     LKGQRDGHEFIDLAFQNGAVATFSEKELSGKPHLLVEDCLKAFQKLAHYYIDKMRVDV
                     IAVTGSNGKTSTKDMIGAVLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMG
                     QDHMGDIRLLSEIARPRIAVLTLVGEAHLEYFGSRNKIAQGKMQIVDGMNSDGILIAP
                     GDPIIDPYLPENQMVIRFGNQQEIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNAT
                     NAMVAAYVGKLLAVTDEDIIAALQTVTLTGNRTEWKKAANGADILSDVYNANPTAMRL
                     ILETFANIAKNPGGKKIAVLADMKELGKDSVILHSQLIDSLTSGNIDQLVFYGDHIKE
                     LARLASQVYPAEQVHYFLKTEQEDQFEAMAQYVQNILNPFDQILLKGSHSMSLEKLVD
                     RLVTDKNCDSYQP"
     gene            117163..117858
                     /locus_tag="VB649_000107"
     CDS             117163..117858
                     /locus_tag="VB649_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEP1669095.1"
                     /translation="MDFFAIDPIGLPHTSLIFYLSSLLIALLLVFLTFQAYRLKSYRY
                     FFLFLQLSQVIGLYTWYVLRGFPLDEALPLYHCRIAMLAIFFLPDRNKFKQLFMVLGI
                     GGTFLALLSPDLYPFRLWHVANVSFYLGHYALLVNGLIYLLRFYDASQLRLLSVVRYL
                     ATVNFLLLLVSLATKGNYGFVMDIPVIHTRHLLLNFVIVTSGLTFMVKITEYFYLKFG
                     EAQQLAFAFSKEK"
     gene            118106..119650
                     /locus_tag="VB649_000108"
     CDS             118106..119650
                     /locus_tag="VB649_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEP1669096.1"
                     /translation="MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKED
                     IELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGN
                     VVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     PKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     TLEEKM"
     gene            119957..121576
                     /locus_tag="VB649_000109"
     CDS             119957..121576
                     /locus_tag="VB649_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP1669097.1"
                     /translation="MKFTEFNLSQDIQSAVVTAGFEKASPIQEMTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTNENIIQALVIAPTRELAVQSQEELFRFGREKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALILDHVETLILDEADEMLNMGF
                     LEDIEAIISRVPADRQTLLFSATMPAPIKQIGVKFMKDPEHVQIKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVNQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLSMIENLTKKQMKPLRPATAEEAFQAKKKVALKKIERDFADE
                     TIRSNFDKFKGDAVQLAAEFTPEELALYILSLTVQDPDSLPEVEIAREKPLPFKYVGG
                     GHGNKNGKGGRGRDNRNRGDRRGGYRGDRNRDERDGDRRRQKRDKRDGHDGSGNRDFK
                     RKSKRNSKDFFNKEKKSSAKNTGFVIRHKGE"
     gene            121703..123703
                     /locus_tag="VB649_000110"
     CDS             121703..123703
                     /locus_tag="VB649_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEP1669098.1"
                     /translation="MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQG
                     GVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKISPWL
                     IIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLF
                     GIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKH
                     SGIELNPFFASVPSQLRVYLVSLATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVT
                     YPGANLGQLYIPVINWILFAVTSCTVLAFRTSAHMEAAYGLAITITMLMTTILLKYYL
                     IKKGTRPILAHLVMAFFALVEFIFFLASAIKFMHGGYAVVILALAIVFVMFIWHAGTR
                     IVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDHMIDRSILYSILDKR
                     PKRAQVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMHTKASIKHVT
                     ASPMRWFGLQYSEVTLEVVPLILSDILKLPIKELMPVEDSEA"
     gene            complement(123727..124005)
                     /locus_tag="VB649_000111"
     CDS             complement(123727..124005)
                     /locus_tag="VB649_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEP1669099.1"
                     /translation="MTTKKAYMYVLECADKTLYTGYTTDLKKRLATHNAGKGAKYTRY
                     RLPVSLLYYEVFDSKKAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH"
     gene            complement(123995..124771)
                     /locus_tag="VB649_000112"
     CDS             complement(123995..124771)
                     /locus_tag="VB649_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEP1669100.1"
                     /translation="MIKAILKEGERIDQLFSSDVGIIQNKDVFSYSIDSVLLSRFPKM
                     PSKGLIVDLCSGNGAVGLFASTRTKAAIVEVELQKRLADMGQRSIQLNQLEDQVTMIC
                     DDLKNLLNHVPRSGVDLMLCNPPYFKSHESSKKNVSEHYLLARHEVTTNLEEICQVAR
                     HALKSNGRLAMVHRPDRFLEIIDSLRANGLAPKRVQFVYPKLGKSANMLLIEAIKDGS
                     IEGMTILPPLVVHKENGEYTDHIFEIYFGAASKGKPNHDH"
     gene            124889..125629
                     /locus_tag="VB649_000113"
     CDS             124889..125629
                     /locus_tag="VB649_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEP1669101.1"
                     /translation="MFYAYLRGLVVFLLWVVNGNAHYHHEEKMLDASENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFANRLFAWWIKMCGAFPIDRDKPSPDAIRYPVNM
                     LKKSNRSLLMFPSGSRHSQEVKGGVAVIAKMAKVKIMPAAYQGPMSVKGLLAGERVDM
                     TFGNPIDVSDIKRMNDEGIAEVANRIQAEFDRMDDELAPFQPGKARNPLTYLYRLPLG
                     LVLVVVLLLTMLFSYIASFVWNPDKHRH"
     gene            125829..126491
                     /locus_tag="VB649_000114"
     CDS             125829..126491
                     /locus_tag="VB649_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEP1669102.1"
                     /translation="MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQ
                     SKAAVPALREISPVKQQVSEEKKKIQEDSSILVDLKGAVQKEGVYKLTASSRVRDVIE
                     LAGGLTSEADKHAINFAEKLTDEQVVYVPKQEEEISVLPRSLVSGKKETASKDQSKVH
                     INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIF
                     LD"
     gene            126472..128715
                     /locus_tag="VB649_000115"
     CDS             126472..128715
                     /locus_tag="VB649_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEP1669103.1"
                     /translation="MTFSWTKLVPLSKIQFAFLILVLFYQIHSPSWLTFLLSLSLICL
                     LVKRLSKKEFLGVFAILSFCALFLLYQKQQLVQKLEIQPVQITSVALVPDSIRINGDQ
                     LAVLGCHGKHSYQLFYRLKSQAEAQLFKKEHRWLVIHAKVTLEKAEEVRNFKGFNYQT
                     FLAYQGIYRIGKVEQIEQLEVISPESICDYLSSLRRRAIVHCQQHFPRPMSHYLTGLL
                     FGYLDKSFGEMTDYYSQLGIIHLFALSGMQVGFFLTCFRRVLLLLAVPLEWIKWIELP
                     FACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFLWDAHFLMTVGGVLT
                     FSYAFLLTVVTVEELSGAKRQLVQVLTISLGILPFLLFYFSSFNPMSMVLTGLLSYLF
                     DLFILPLLCLVFCLSPLVTVSICNHLFILLEKVIQFLGNTFNSSLVFGSPTSWHLLIL
                     VISFAIFYDYRQVRQRVITCGLVIALTLLSVKYPLTNEVTFIDIGQGDSILVREWTGK
                     NLLIDVGGLPFFSSKEHWRRGHHVANAQKTLIPYLKSRGIHTIDQLLVTHADTDHMGD
                     IEVVAKAIRIKEILTSQGSLSHPSFVRRLRRLKCHVRVLAAGDQLPIMGSVLQVLYPW
                     QLGDGKNNDSLVLYGRLLNRTFLFTGDLEKEGENEIIKRYPQLRVDYLKAGHHGSNTS
                     SSAAFLDHIQPKVAFISAGKNNRYQHPHRETLARLEDRQITYYRTDTQGAIRLTGWTS
                     WHLETVR"
     gene            128786..129826
                     /locus_tag="VB649_000116"
     CDS             128786..129826
                     /locus_tag="VB649_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEP1669104.1"
                     /translation="MIAIEKIEKLSKENLGLITLVTGDDIGQYSQLKSRLMGQIAFDK
                     DDLAYSYFDMSEAAYQDAEMDLVSLPFFAEQKVVIFDHLLDITTNKKSFLKEKDLKAF
                     EAYLENPLETTRLIIFAPGKLDSKRRLVKLLKRDALVLEANPLKEAELRTYFQKYSHQ
                     LGLGFESGAFEQLLLKSNDDFSQIMKNMAFLKAYKKTGNISLTDIEQAIPKSLQDNIF
                     DLTRLVLGGKLDVARDLIHDLRLSGEDDIKLIAIMLGQFRLYLQLAILAKEGKSEQQL
                     VTSLSEILGRRVNPYQVKYALKDSRTLSLAFLTGAVKTLIETDYQIKTGLYEKSYLVD
                     IALLKIMTHSQK"
     gene            129923..130528
                     /locus_tag="VB649_000117"
     CDS             129923..130528
                     /locus_tag="VB649_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEP1669105.1"
                     /translation="MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALE
                     KHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTPDVAQA
                     IDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIVNWKKVSELYQAAK"
     gene            130695..130877
                     /locus_tag="VB649_000118"
     CDS             130695..130877
                     /locus_tag="VB649_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669106.1"
                     /translation="MLREKKTTIVGIILGMMIVTLLVGCLTGKKKGFPPKAGERQQTA
                     DLKMKKRLENCSKTVT"
     gene            130906..131154
                     /locus_tag="VB649_000119"
     CDS             130906..131154
                     /locus_tag="VB649_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669107.1"
                     /translation="MDADLAQMDVLGLYYDDNHLSLVNTVKAYLKEFGIGESQIAFSY
                     KDLNSGRTAAMNDHQPMIAGSTYKLPLNMLVVDKANYP"
     gene            131151..131728
                     /locus_tag="VB649_000120"
                     /pseudo
     CDS             131151..131728
                     /locus_tag="VB649_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S11"
     gene            complement(131842..133062)
                     /locus_tag="VB649_000121"
     CDS             complement(131842..133062)
                     /locus_tag="VB649_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEP1669108.1"
                     /translation="MKLLGKWLFFLMFLTFCVSFWQKDYQRIAFEKEHKSYQDLVAPF
                     YQNYPKLRELQLSEAIKLRHDLLDYVRKLDKDGWSYKAIQKGYLEQLAVRGNSYHFEQ
                     LYSRIRLIGSPDFQKLWQQEEMAQTPQEAQKRLQLLLTYLKMPDELTGQSKQTQQVLA
                     QLSPKLSPTDPFWDQLSALIQACYVNLEHIPYSRFNRKIHQLRYLISTQQTEWVRSHY
                     GNKGKTDADALAKYLATLEDDDYALYESSRYHNKVASILDANGNHQAVYTDNIPQANY
                     KILIHFHSEFILSESGQFLVALDPDNLTRNSIVNGSSFNYGNQNDDLHRLLDIDPILL
                     FDPAFIEKAINSPDATFLVPDLEQQRDKHNPIYSRNGKSSKQLTRAAVKKFKKLLHHY
                     QETRGDNKTSKTQH"
     gene            complement(133069..134097)
                     /gene="queA"
                     /locus_tag="VB649_000122"
     CDS             complement(133069..134097)
                     /gene="queA"
                     /locus_tag="VB649_000122"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEP1669109.1"
                     /translation="MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGEKPDTHGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGSQVNFGDGHLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
                     AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHDMHSEFYSLSEEAAQTLRDVKQAGGRVVAVGTTSIRTLETIGSKFQGDIQADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAERDFVLEAYRHAVDEKYRFFS
                     FGDAMFVN"
     gene            134299..135003
                     /gene="nagB"
                     /locus_tag="VB649_000123"
     CDS             134299..135003
                     /gene="nagB"
                     /locus_tag="VB649_000123"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEP1669110.1"
                     /translation="MKIIRVQDQIEGGKIAFTLLKDSLAKGAKTLGLATGSSPISFYQ
                     EMVKSPLDFSDLTSINLDEYVGLSVESDQSYDYFMRQNLFNAKPFKKNYLPNGLATDV
                     EAEAKRYDQIIAEHPIDFQVLGIGRNGHIGFNEPGTSFEEETHVVDLQESTIEANSRF
                     FTSIEDVPKQAISMGIASIMKSKMIVLLAFGQEKADTIKGMVFGPITEDLPASILQKH
                     DHVIVIVDEAAASQLD"
     gene            135122..135838
                     /locus_tag="VB649_000124"
     CDS             135122..135838
                     /locus_tag="VB649_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP1669111.1"
                     /translation="MRLDKLLEGTKVGSRSQVKKLIKAQGVWVDHMPARNGRQNVDPG
                     LQLIEVTGQRVTHPKHSYIILNKPSGVVSAKKDTNYLTVIDQLAEEDKSPDLYPVGRL
                     DRDTEGLVLLTDNGPLGFRMLHPSHHVSKTYLVTVNGLLAEDASDFFAAGICFPTGEQ
                     CQPAQLTILKADTDQSQASLTISEGKFHQVKKMFLTYGLKVTSLKRTHFAGLELGHLA
                     SGEYRYLTASERQLIKTYLD"
     gene            136133..137095
                     /locus_tag="VB649_000125"
     CDS             136133..137095
                     /locus_tag="VB649_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEP1669112.1"
                     /translation="MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTI
                     RRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLVRTEAVCIEKYLPELQQIADLWV
                     NDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
                     SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYS
                     YQKKMTVNLSKRIQRALLARHPKWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSG
                     FCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK"
     gene            137108..138913
                     /gene="pepF"
                     /locus_tag="VB649_000126"
     CDS             137108..138913
                     /gene="pepF"
                     /locus_tag="VB649_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEP1669113.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFS
                     GHLLDSSANLLTITDTYLELARRVEKVYVYAHMKNDQDTTVAKYQEYQAKASGLYAKF
                     SEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSIRQAAYEAI
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGKDYA
                     DRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQKGEVLTSEYLNQLYADLNEKYYGLSKKDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS"
     gene            139289..140485
                     /locus_tag="VB649_000127"
     CDS             139289..140485
                     /locus_tag="VB649_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEP1669114.1"
                     /translation="MEKTKRYIIATAGILLHLMLGSTYAWSVYRNPILEETGWDQAPV
                     AFAFSLAIFCLGLSAAFMGNLVEQYGPRLTGTVSAILYASGNMLTGLAIDRKEIWLLY
                     IGYGVIGGLGLGAGYITPISTIIKWFPDKRGMATGFAIMGFGFASLLTSPIAQWLIET
                     EGLVATFYLLGLIYLIVMLFASQLIIKPTAAEIAILDKKRLQNNSYLIEGMTAKEALK
                     TKSFYCLWVILFINITCGLGLISVVAPMAQDLTGMSPEMSAIVVGAMGIFNGFGRLVW
                     ASLSDYIGRRVTVILLFLVSIIMTISLIFAHSSLIFMISIATLMTCYGAGFSLIPPYL
                     SDLFGAKELATLHGYILTAWAIAALTGPMLLSITVEWTHNYLLTLCVFIVLYILGLMV
                     ALRLKK"
     gene            140551..141258
                     /locus_tag="VB649_000128"
     CDS             140551..141258
                     /locus_tag="VB649_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEP1669115.1"
                     /translation="MVKSYSKTANHNMRRPVVKEELVHYMRTRQKQTTGFLAELEQFA
                     RQENIPIIQPEVVAYFRFLLQSLQPKHILEIGTAIGFSALLMAENAPDATIVTIDRNR
                     EMIDFAKANFAKYDSRQQIRLLEGDAADILSTLEGNFDFVFMDSAKSKYIVFLPEILR
                     LLKVGGVVILDDVFQGGDITKPIEDIRRGQRTIYRGLQSLFDATLTHPNLTTSLVPLS
                     DGLLMIRKNQADIVLPD"
     gene            141321..142376
                     /gene="prsA"
                     /locus_tag="VB649_000129"
     CDS             141321..142376
                     /gene="prsA"
                     /locus_tag="VB649_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEP1669116.1"
                     /translation="MKNSNKLIASVVTLASVMALAACQSTNDNTKVISMKGDTISVSD
                     FYNETKNTEVSQKAMLNLVISRVFEAQYGDKVSKKEVEKAYHKTAEQYGASFSAALAQ
                     SSLTPETFKRQIRSSKLVEYAVKEAAKKELTTQEYKKAYESYTPTMAVEMITLDNEET
                     AKSVLEELKVEGADFTAIAKEKTTTPEKKVTYKFDSGATNVPTDVVKAASSLNEGGIS
                     DVISVLDPTSYQKKFYIVKVTKKAEKKSDWQEYKKRLKAIIIAEKSKDMNFQNKVIAN
                     ALDKANVKIKDKAFANILAQYANLGQKTKAASESSTTSESSKAAEENPSESEPTQTSS
                     AEEPTETEAQTQEPAAQ"
     gene            142763..145381
                     /gene="alaS"
                     /locus_tag="VB649_000130"
     CDS             142763..145381
                     /gene="alaS"
                     /locus_tag="VB649_000130"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEP1669117.1"
                     /translation="MKELSSAQIRQMWLDFWKSKGHCVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPDWFDFPKDKLYMTYYPDDKDSYNRWIACGVEPSHLVPIEDNFWEI
                     GAGPSGPDTEIFFDRGEDFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREVEKLSGKTYNPDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGINETFLYKLVPTV
                     GQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSGHLDSLLTQLKAEGKDTLEGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKSAMKEQQDRARAAVVKGGSMGMQNE
                     TLAGIVEKSRFEYDTYSLESSLSVIIADNERTEAVSEGQALLVFAQTPFYAEMGGQVA
                     DHGVIKNDKGDTVAEVVDVQKAPNGQPLHTVNVLASLSVGTNYTLEINKERRLAVEKN
                     HTATHLLHAALHNVIGEHATQAGSLNEEEFLRFDFTHFEAVSNEELRHIEQEVNEQIW
                     NALTITTTETDVETAKEMGAMALFGEKYGKVVRVVQIGNYSVELCGGTHLNNSSEIGL
                     FKIVKEEGIGSGTRRIIAVTGRQAFEAYRNQEDALKEIAATVKAPQLKDAAAKVQALS
                     DSLRDLQKENAELKEKAAAAAAGDVFKDVQEAKGVRFIASQVDVADAGALRTFADNWK
                     QKDYSDVLVLVAAIGEKVNVLVASKTKDVHAGNMIKELAPIVAGRGGGKPDMAMAGGS
                     DASKIAELLAAVAETV"
     gene            145742..145957
                     /locus_tag="VB649_000131"
     CDS             145742..145957
                     /locus_tag="VB649_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1669118.1"
                     /translation="MEVILKNRLKELRARDGINQTEMAKLAGVSRQTISLIERNEYTP
                     SVIIAMKIAKVFQEPVEEVFRLVEVEE"
     gene            145954..146715
                     /locus_tag="VB649_000132"
     CDS             145954..146715
                     /locus_tag="VB649_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEP1669119.1"
                     /translation="MKKKKNSFLRLLKMLLLSSLAGGIIGGMVGAFLGYHGERLDQLT
                     FLKDDVINLIILLNRLVVVTGLTLSFVFLTQLKKETAVYNTIEEDDYSENGYRQLNKK
                     HAYTMLLIAVASILSMCNVLLGLTLTNDSQHAMLAIPLLDILLLLMVIPFQALAMKRY
                     NAIRGTDVPYFPNLKELKHNIMALDEAELQAYHKTSFESVLSLNGVIIPSLYVILFFV
                     YLFTGQVELTAILVLVLIQLYLLVKSATMTRQFYR"
     gene            146734..147429
                     /locus_tag="VB649_000133"
     CDS             146734..147429
                     /locus_tag="VB649_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEP1669120.1"
                     /translation="MKGFINYLKIAVLIILAMVFNVLPMILLQKQHDIPMVLNWGIGI
                     FYLVIVGSVLIVLWRLYQAKQDTPIKQQKMRLVDWGYLALFWLIIRVIAIVGTLVNQL
                     WSGQQVSANDAAIHTLARLIKGGFPLYTALFVLVIAFIAPIMEELVFRGFPMIDLFKG
                     KSLKVAGLVTSLVFALPHATNSVEFIMYSCMGIFLFVAYQRRGNLKDAILLHIFNNLI
                     EVILLMSIGLGVI"
     gene            complement(147526..>147641)
                     /locus_tag="VB649_000134"
     CDS             complement(147526..>147641)
                     /locus_tag="VB649_000134"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP1669121.1"
                     /translation="QAQLEIFKYSETYYNPKRLPSALGYLSPVEFEKIVTH"
BASE COUNT        45464 a        26170 c        31290 g        44717 t
ORIGIN      
        1 ttttattgtt tatttttaat tgcagattgg ggtttaaaag acactttaca atgttctcaa
       61 gtcatgtgtt gttgtaggtt gtatgcacat attacaaatc ccattataaa agaaaatgtg
      121 gttttaatgg taattttagc agttatagta agacaaaagg tgacttggaa aagcttatgc
      181 agacgattct taactcccac aatatcttct gtcagatttt attagacttc ttctcagtgt
      241 caattttgtc tgttttacga acgtgcaggc tattcaattg cttcttagct tctaaaggat
      301 taaaccgagt ataagcgtag ccattatctg cgaaaaaacc tgaagacgac gagaatagac
      361 attaatcgtt ttaaggataa tctcagggtt atggacggtt ttcaagtttc caagaagatg
      421 attgaggccg atggtatcgt tttgtcttga atgattcctt attttagtgg tttcattttc
      481 aatacacgac gtcaagcgtc ctacatactt tgataaaatt ctacctaaaa gaggtgtctt
      541 gtcagttttg gttacaacat caagtgccaa aagactttgc gacttaacaa gacacttcta
      601 ctttaacgca aagaaaaagt agtgagtact ctctttcgtc ggagatttcc tcgctactaa
      661 acttagtatt ttttgatact ttccttaggt agtgcttaag gcagcgactt tctttggaat
      721 tccatgcctt atttttgaga tcctaggctc aaaaatgcca agtggcgtca acattaacat
      781 tgacgccact tttaccacaa cgaaaaacat ctgttttggc tcactccaca cgcagaaata
      841 ggaaattgga tgtcaaatca gcagagctgt tcatgctttt tgagcctaaa actgagtttg
      901 tctgcgttct gagcactcct tgggagtgct ggacaactct taacgattct tcagttcaag
      961 ataacgtttg taccaaatag tgatataggc cttggaaaat ggtccttttt catgattaat
     1021 ccaatcaacc aatattttga cattttcttt taggataaag tccatatcgg ctgaatactg
     1081 catctctttt ttatgaatct cgtattcatc aacatcaagt aatctctttt caccatccgc
     1141 aaagactttg acatctaaat cgtaatcaat gtatttgagg gcctcagtgt ccatcatgta
     1201 tggactagct aagttacagt aataagagac gccattatct cgaatcatgg ctataatgtt
     1261 aaaccagtat tttttatgaa agtaaacgat tgcaggttcg cgggtcaccc atcgtctacc
     1321 gtcactttct gtgacaagag tgtgatcatt aactccaatg agggcatttt cagttgtttt
     1381 tagtaccata gtatcgcgcc aagtacggtg caaactacca tcatgcttat aactttgaat
     1441 tgtaataaag tcgccttctt taggtaattt catgccttac caactttcta caattaaact
     1501 tatcctctat agtctatcat aaatgtgtga aaaaatcact tcttttgtca gtctataaat
     1561 aatttcttaa cttgcaatta atatcgtcgc tgttgtagcc ttttcggtag agagcctgat
     1621 agagcttttg ctttaaggta taaccatcat atttgcgact gagtttacga tattgtttgt
     1681 ctaattcttt gtcaagaaga tcttctattt cttgattatc ttggtcaaaa ttaaggtgat
     1741 tgaggctatg tttagctaga tcgtatgaaa agcctttggt cagtaatgct tgggtgattt
     1801 tatctttcaa ggcttttggt ggcaattttt cttgatattt gtcaaagagt ttttggctta
     1861 ctttttgagc gagttggcta aagtcagttt gagataagat aggatcaatg tcatgacttg
     1921 caatgccttt ttgtaataat ttttgtttta agacttgggg acctttatca ccatttaact
     1981 gattttggcg aatgtaggta tcagccaatt tggtgtcgtc tatccattgt tcttcttgga
     2041 gttgagtgat gatgtcagca ataatgtgtt cttcaatctc atgcttgcgc aggtaatcag
     2101 caacttgctt gttgctgcgt tgttgaaagg aaagaaaata aagggctaaa tttttgccgt
     2161 aggacagttg ggcaaaatgt ttcatgtctt caagctgatc attgtcaagg actttatctt
     2221 tactcaacat aaaccgaaca atagtatctt ctgttacata aagggattcg tcattatcca
     2281 attcgataag gtagaggcgt tttttctttt caattttagt gattttcata tgttcattat
     2341 atcaaaaatg gtaaaataga agatgaaaat actgctaaaa atgtgttgct tgtgaatgct
     2401 tttggtggtg agattaggat attagaggaa gtaaggggaa gagatggtcg taaaggttaa
     2461 acagaaaatt cctttaaaaa ttaagcgaat gggaattaat ggtgagggga ttggttttta
     2521 tcagaaaact ttggtatttg tccctggtgc tttaaaggga gaaaatattt tttgccaaat
     2581 cacggcggtt aaacggaatt ttgcagaggc caagctgtta acggtaaaca aggcttctaa
     2641 gaatcgtgtc aaaccagctt gttctgttta tgaaacttgt ggtggttgcc aaatcatgca
     2701 tctagcctat cctaaacagc tagatttcaa agatgatgtg attaggcagg cccttaaaaa
     2761 gttcaaacca actggctatg aacaatttga gattagaccg actttaggaa tgaaaaagcc
     2821 agatcactat cgggccaaat tgcagtttca gttgcggtca tttggcggga cggtcaaggc
     2881 tggtttattt tcccagggaa gtcatcgctt ggttcctatt gacaattgct tggtacagga
     2941 tcaactaacg caagatatta tcaataagat tacgcagtta gtggacaagt acaagttgcc
     3001 catttacaat gagcgcaaga ttgctgggat tcggacgata atggttcgta aggcacaggc
     3061 tagtgatcag gtacagatta ttgttgtgag tagcaaagaa gttcggttag cgaatttctt
     3121 tggcgaattg actaaggcat ttcctcaggt taaaacggtt gccttgaata gtaatcgttc
     3181 taaatcgagt gagatttatg gggacgaaac ggaaattcta tggggacaag aggcgattca
     3241 tgaagaagtt ttagactatg gatttgcgtt atcaccgaga gctttttacc aacttaatcc
     3301 acagcagaca gaagttttgt atggtgaggt ggtgaaggcc ttggatgtag ggagcaaaga
     3361 tcatattatt gatgcctatt gtggggttgg ctcgattggc tttgcttttg cagggaaggt
     3421 caagtctgtg cgggggatgg atattatccc agaagcgatt gaggatgcac aaaaaaatgc
     3481 caaagccatg ggctttgaca acgcttacta tgaggcaggg aaggcagagg atattattcc
     3541 taaatggtat aaacaaggtt accgcgcgga tgccgtcatt gtggacccac caagaactgg
     3601 tttagatgat aaattattaa aaacgattct tcattaccag cctaaacaga tggtttatgt
     3661 gtcttgtaat acctccactt tggcccgcga cttggtgcag ctaacaaagg tttacgatgt
     3721 tcactatatc caaagtgtag acatgttccc ccatacagct aggaccgagg ctgtcgtgaa
     3781 gttacaaaaa cgtgtatgat tgagtggcaa taacaactca agttttataa gctcaggtaa
     3841 tgggtttgag caatagcttg acatagtagg gatgtcaaaa acggtttact aagcatagtc
     3901 atattattga taactctatg tttattttag aaacattcat ggttaaaaaa gtttgttagt
     3961 ttgtcactaa gtagggtcta tttgaagagc aagtacacac agacaatatt aggggaattg
     4021 attgttgaaa aaaagctggt ttttgctata aattagaaaa ctgagtggtc aggaggttac
     4081 attaccagaa gttattttag tatgctaata tgaacgatga tatagaggat ttatcctgat
     4141 ttaatctttt aagctgtaag aaacctttgc aaaaactgta ggctgtgtga gtctttatgt
     4201 gttagatatt aaagataaaa acaacacttt tttataatga gatcaacaac tgataaatct
     4261 aagttgataa ccagtaaaat gatcggaatg tagaaaagtt acttaatcaa gcttttcgta
     4321 atttaactgt tagaatgaca gaacttatga taaaataaag aatatgatta aaatgaaaaa
     4381 gctcagttta tctattacgg agttcgaaat gaaaagaaaa tcgagatgtg ataacatatt
     4441 ttgaacgaga aggagaagga taaatgttag aagattttct tcaattttta ggatttatat
     4501 ttttagatat tattgaaatt atgttaacgt taaagctttt tagctttgta agtgcaattc
     4561 cgcttcgcct gaaaaatatt ttttatttat cacttagtat ggttttgttt caagtagttt
     4621 tttgggcttt ctttccagac catttcattc ttgatgttgt gatgttggca cagtttcttt
     4681 tctttgcgct tatagcccta tactatggta aatcaataaa agctaagttt ttaatgtttt
     4741 atgccttttt tccactagtg tctattagtt tggttaagcg atttattgta ttttttgtta
     4801 tgccattgtt tggtatgcct tattcagttg ttaaacataa tacactactg atttacagca
     4861 ttacttgctt tagtattttt ttgatttatc gctgcattca agtttttcat ttcgattttt
     4921 caacctggcg ccaatatttt caatcacata gagctagtaa actattagtg tttactaact
     4981 cttcgatggc tctatactac ttgtgtgtcc aagggataga tgtgatgtcg ccttctttat
     5041 caggacttgc tacaacgact gctcgttcaa tcatagtgct cttttatttc attttgtttc
     5101 ttactttatt aattcattta gagcgttatg taaaacaaaa ctctattgag gcaattgtgc
     5161 aacaaaaaga atatcgtgag ctgattaatt atagtcagca ccttggattg ctgtatcaag
     5221 atattcaaga gcttaggcag ctattaacta ccgtgtccag tcgtcttaag attggaatcg
     5281 aacaaaatga tatctctatt gtgagactta cttatgaagg tatcttgaat gctgaaaaga
     5341 ataatgttaa agatgacaga cttgatttaa cttgtttaga taaattacaa gttgaagcaa
     5401 tcagacatat tgttttagct aaattaattg aggcaaaaaa taagaagctt aaggttgagg
     5461 catcgatccc taattgtatt gcaacgtttt ttctagaagt agtagatttc actaagctat
     5521 tgtcattttt gttagataat gctatagaaa tgagtttgga gacaaagcaa ccttgcttat
     5581 caatagcatt tctggatcaa aaccataaac ttgtcatagt cattcaaagc agtactaaac
     5641 aaggacaaga tgatagtcaa agcgtgtttg ctataccggc tttgaaaaaa agagatgact
     5701 ggcaatttga cttaaggaat gtcacgacca ttttaaatcg ttatgactat ctcacaatta
     5761 gctcgcagat tcatgatggc attttaaccc agttaataga aatagctaag cctgactgat
     5821 gttaaaggta ttaataatca ctcaaaatca acttaagagt ctgagacaat agtcccagac
     5881 tctttttgaa tatgttaatc tattactaat gataatagtt tattgtttct tccaagctag
     5941 agttaaaatt tccgctttgc caagttggct gggtgtgctt tgcttgctgt ctttttctaa
     6001 caaattagtg accttggcat tgtagtttgg caggcttagg ctaaagtcac aagttttatc
     6061 gtttgagaga ttatagctgc gcgtgataag ggcattgtct gatgggcgac gtttgaaagc
     6121 tgttagagcg acttgatcgt ctgcaccagt gacatagcta tgctctgctc ttaagcttcc
     6181 cgtatgatgg ctggtttgtt cgactaggat aggaacttgg ccttcttgtg cccgccaata
     6241 gctggcaaat tgtgtttgcc tatcgatgct ttcaaaacta taagataggc tatgctggcc
     6301 aagacactgg gcttcaggtg ttgggaagta accccagtcc cccatctcac caacagaacg
     6361 taagagagtg atggcaatgg tgttgctatc tggtaaaatc tcatattcgt tgaggccgta
     6421 gttaccaata gtgaccccct tttcaccatc aaagagactc acaaagcatt cttggtgctg
     6481 tgggttactt ggattcttcc aaaaggtggc atctggatga tttggacgtt tgacagtttc
     6541 aaaaatactg tcagctagat gatggtctgt tttaaggtgc gttgggaata ggacgcgcaa
     6601 gcgatgatta gtcatttggt tatcaaaacg tgtggtgaat tggaggcgag gattgttttt
     6661 ctccatgcgg ataagggttg ttaaggttag ctcagccttt tcttgtgaac gtcctgattg
     6721 gcgttctgtg atgtcaatga cagcctccat ttcagcctgt aagagcttat ctgcggagac
     6781 aggaatggca aaggtttgct ggatttcaag ttcagcaact tgagcggtgt tgctaatgat
     6841 gttaagcttg gtggtccctt ggtctgcata gaaaggttgg tcatgatttg gttggcggga
     6901 aatgtattca tttccaatat cgccacaatc ttcaaactgt aggagatctt gatagctcac
     6961 ctctgactgt ttatcggtga tggttagacg accatcggtt tgtatcataa cttttagaaa
     7021 ctcattttca aggcactgat tactatcgtc gtagagtggg accgttgctg aaggagctgt
     7081 ctcgtttcct agttgtaatg ctaaggtttt ccaagacatg gctgggagag ttattggtag
     7141 ccgtaatctc acttttatgg cgaaataagg ttctcggaag gttctcttgg acaaatcgta
     7201 gtcaaaagcg atgcttgtgc ctaaaatttc tgcttcgggt ctcacttgtc cactagtgtc
     7261 aataatttgg aaagattggg agagtcttgc caaatattct tgagcttctt ggtaaacctc
     7321 tttaggaaag cgttgaccaa aatgatatgt tttccaggtc aggctgagct cagcaacact
     7381 tgttttggaa tggccgctgg tattaaataa gacgaagggt tggctatcca ttggaaaatc
     7441 cctggtatca atggcgtcag caatttgctt agcagcttct tttgctaaat agtgtccgac
     7501 ttcataggct ttttcaaagc gcgtcatcat ttcccgatga acgctatcaa cactacaacc
     7561 acagatagaa tcatgagggt gattttgcat gagggttttc caagcgtaac gcagttggtc
     7621 gtgagggtag gtacttgtta cctcataagc cattgctgct aagggttcgg tgatgttttc
     7681 gagttggcga gagactctgg tattagcctg tttgaggtaa atacgagcag aagccgtgtt
     7741 agctagggta taccagccat cggtttcttg actggtaatc tctccttgga cggttgaaag
     7801 gttctctggt aaatcatctg cgagatcagc caagtaatct tcaaagcagg aatgcacaaa
     7861 ttcgtagtca ggatagagtt ggttggctaa ggcgattgcc ttggtgacat caagttgtac
     7921 gggttgatga tcacacccgt tcatcatcag aaggtgcttg gttgaggcga agcgttcggc
     7981 gtcagcaagt tttttatccc aaaaaagacg cgcctcagct tctgttgtcg ggatctcatt
     8041 gccattgctg taccagttgg cgaagaggag tccaagaata cgactgtcat ctggtccttg
     8101 ccaactgatt tcagagaatt gggagctgta tttttcactg gtatctactt gattgttaaa
     8161 tccagttgga cgaatgccac gaccaaaggc agcagcttgt aggccggctt ttaacatcag
     8221 ctgtggtgtt tgtcccatat ttccaaaggt atctggaaaa taaccaagtg gcacactagc
     8281 gccccatttg tcacaatcct ccttgccaat gagcatattg cgcacattgg actcgctgct
     8341 ggtcaaaaaa tcgtcctgta agatatagaa aggtccgata cggagttttc ccgaagcaat
     8401 ggcttgtcta atctcaggtt ctcgttcggg gcgtactttt aaataatcat ctaggataat
     8461 ggtttgacca tccaaatgaa aactatgaaa attaggattt gtttgaaaaa cttctaacag
     8521 gtcatctatt aagttaatca gacgcatgtg gtgttgctcg taagccatgt accactcgcg
     8581 atcccagtga ctgtgtgaaa taatatgtac ttttttggtt gccatagtgg cctcactttc
     8641 taaggagcaa tgctaaagcc aagatagtca agaagtagtt cacagaacat catgttagcc
     8701 caagagaacc actcacgggt gtattgataa ggatcattga catcgaaacc ctcgtgcatt
     8761 aagtgggtac cagcatctgt tgccacaagc aaatcaagca tctctttttt actgtcttgg
     8821 tcaagagcgg tcaatccttg taaggcaagg gcgatatgcc agatataatt ttctggtgta
     8881 tgggaagaac cgatgcctgc tgctgcattt ccctgataat aataagggtt ttcttggctg
     8941 aaaatggtgc ggcgcgttgc cagatagata gggtcatctt tagcacaaaa accaaggtaa
     9001 ggtgcagcga ggaggcttgg aatattagca tcatccatga tggaaaactg tcccagacca
     9061 tccacttcat aagcgtaaat ggtttctccc ttgctgtttt gaacaagggc atggtctgca
     9121 atacctgatt gaatagcttc ttttagctgc ttggcacgag tagctattgg ttcattgtga
     9181 aaaaggttgt tatataaatc ttctagatag gaaagcacaa ccactgcaaa catatttgaa
     9241 ggaatgaggt aaccatattg acaagcatca tcacttggtc taaagcctga ccaggtcatt
     9301 cctgttggtg cgacaggact tccttttcca gcatgtgtta aggtatcttc tttgcgccaa
     9361 gtatcgcgtt caaacaagta aggagactgg gcgtggtctt gctcaactgt ccataggtca
     9421 agaatgagtt ctaccccacg atgaaaatcg tcattaaact gatcggtgct tcctgtttca
     9481 cgatagagca gataagccag ttgaataggg tagcaaaggg aatcaatctc atatttgcgt
     9541 tcccaaatcc aagggttcat ttgggtatga tctgtttggt gtcctttttc gttagcttct
     9601 tcgttgaagg cattggcata gggatcgata caaatgtagc ggaattggcg tttgaccaga
     9661 ccggcaataa tctttctaat ttcttcatct tccttggcga ggaagaggta aggtttcatt
     9721 tgcgcagtag aatcacgtaa ccacatggca ggaatatctc ctgtcaagag aaagctagtg
     9781 ccatcttcgt aggtttttag ggttgtctct aaggtattgg taaagctggt tttgaaatta
     9841 agagcccaat cagggtgttg gtctccacaa aggctttcca ccttggccat aaattggctg
     9901 acgctagttg ggattggtcg tgtcatgtca tatcctccaa aatgatatat catttatctt
     9961 cggtttcatt ataaatgata agttaaactt tgtctataag tttttgaaaa ggtttacaac
    10021 tcttttttga catgctatac tgataacggg agtaaagaat gacaaaatta ttatacaaaa
    10081 agatatatca tttcattaaa gagcagatag aatcaggtcg tttgcaaatt ggtgaccgcc
    10141 tacctactga aaaagaattg tcagaacaat tttcggtaag ccgtattact tctaaacgag
    10201 cgcttgtaga actggagcaa gaaggcctga tcacgagaag tcgtgggaaa ggaagcttcg
    10261 tagctgagaa gcaagtgacg tcccctgaag cgaataagga tttattgttg attcttcctt
    10321 ttgcttctga ttatgaattg ggagattatg ctaagggaat tatgacctcc attgctgaaa
    10381 caggttaccg tctcatggtt caattggcca gtacggtaag gttagacacc ctgtcagact
    10441 atgctggtat tatttattac ccagaagatg tcaatcacag tattgatttc ctgttttact
    10501 gcgaccatca tcacattcct ctagtcttgt tggataaatc tctagatctt tttcagtttc
    10561 cgtctgttgt agcggataat aaaggcggtg cctgtcaatt gactcagcac ttgattgagc
    10621 aaggctgtga ccagattagt tttgtggcaa caggctcttt tggagaagta tcatccgtta
    10681 gagaccgtta tttgggttac ttagcggcaa tggcagaatc gtctctaaaa tcccattatt
    10741 ttcctaagac agagactgaa acaacagatg cttatttgga ccgtttggtg aaaaccttat
    10801 cggaaacgac agccactaaa agggggcttg tcgtggaaaa cgattggttg gctattcagc
    10861 tgactcaaaa aatcacacag gtaggcttat ctattcctga tcaagtcgct attgtaggct
    10921 ttgataatag tcaagcctcc cgtttgttga gtcccaaatt aagcacagca gctcaagatt
    10981 tttaccaaat ggggcaagaa gcagctaaag tcttgttgca gattattcat gagccagacc
    11041 aagcagtggt gtcttgccag ttacctgttc aagtatttat cagagaaagt agtcactaaa
    11101 aaagacgtta ctagcatgag ctgtttagct caggtaaagg agaccagaaa tgaccattta
    11161 tcacacctta aaggattatc aagaagtcat gacaagagga gactatcttg tctttgacac
    11221 gccattgact tgccgattta ttggccgttt tttccgcttt gaaaatcaaa aagccctgct
    11281 ggcagaattg gcaacgtcaa agtattttca gtggattgaa gaaggccaag cagaggtgac
    11341 gatgaaacac ttttttaacc gtcagctggc taaggatgcc tttaccctga aggtttcaga
    11401 agataaggaa atcattattg aaagccaaaa ccttagaggt tttcgttacg cccaagaagc
    11461 tttgcttaaa gtgatgactt tcaaagggaa taaactttat ttaccgattg tatctgtcaa
    11521 gcatagtcct tcttttgcta tgcgggggat aattgaaggt ttttatggaa caccgtggac
    11581 acgagaagag cggttagatt gcctacgttt cattggacgt aaaaggatga atacttacat
    11641 gtatgctccg aaagatgatg attaccagcg aaaacaatgg cgcgatcttt atcctgagga
    11701 ttgggtgact tatttcaaag agctacttgc agtagccaag gaagaaggga ttgatttttg
    11761 gtatatgatt agtccgggac ttgattttga ttataccaag gaagctgact atcagttgct
    11821 ctatcaaaaa ttgcaacaac ttctagcgtt aggtgtttgt cattttgggc ttttgctgga
    11881 tgatattgac taccaaattg tagatgctgt tgagagacga ttcaaaaaga ctgcctatgc
    11941 ccaggcccac ttggcaactg aggttcatca ctttttaaac caacaacatg cggcgccaga
    12001 attggtgatc tgtccgacag aatacgacaa ccaccatgat tctatctatt tgcaagagct
    12061 gtcagaaagg attcctaaag aagtcgtctt tttctggaca ggcccaagca cgctagcgag
    12121 tcaaatatcg caagcagata ttgaaactat ggcagcagta tatcaacggc ctatcattat
    12181 ttgggacaat attcctgtta atgattatca aaaagatcca gaacgtctct ttttaacccc
    12241 ttttgctaat cgctcaccat ttttatgcca atcagactat caggtcaagg ggattgtttc
    12301 taaccctatg attagttggg aattatctaa gctgaccttg acagacatga gccattatct
    12361 gtgggatgct aaccgttatc agcctagtca ttcttggcta gaaaccttaa cagactatac
    12421 agaagatact gaattagccc tagctttaca ggcatttgct tggcataatg gcaatcgtca
    12481 tctgcacagg gaccttcctt ttgaagtgga agaagctctc ctggctaaga atgtatcaac
    12541 gttatcagct tgggtagatg aattggtcga acgtgtcaat accttgagaa agctagataa
    12601 gccagcgttt caacaagcta ttgctccttg gtttgaacgt gtggccaaag accaagattt
    12661 ttggcaggct atgttaaatc aggagcctca gttggaaaca ctctatgctg acttacaaga
    12721 agataaacac cgcattggaa gtgacattcc aagtcgttac tatcgcatct actatcaaca
    12781 gcaagataaa ctaacagcta atcaaggtca agttacccaa gcaagacctg aagattatgc
    12841 ttagtcatac gagctagaaa ggaatgatat gttagcattt ccaaaagagt tttggtgggg
    12901 aggagccact tcaggccctc aaagtgaggg gcgttttgct aagcagcacc gcaatctctt
    12961 tgattattgg tatgaagagg agcctgactt gttttacgat tacgtgggac ctgatacggc
    13021 ttcggatgcc tatcatcaga ttgaatctga tttgaccttg ttagcttcac taggtcacaa
    13081 ttcctaccgc acctccattc agtggacacg tttgattgat gattttgagc aagcgacgat
    13141 taatcctgat ggccttgctt attataatcg agtgattgat gcttgcttgg ccaatggtat
    13201 ccgtcctgtt attaatttgc atcattttga cctgccaatt gccctctatc aagcctatgg
    13261 tggctgggaa tcaaagcatg ttgtggactt atttgtggcc tttagtaagg tttgttttca
    13321 agaattcggt gatcgggtta aggattggtt tgtccacaat gaacctatgg tcgttgtgga
    13381 aggctcttat ttaatgcaat ttcattaccc tgctatcgtg gatgggaaaa aagcagtcca
    13441 ggtcgcctat aacctagccc tagccacagc caaggttatt caagcttaca ggcaaggtcc
    13501 agcagaactt agtgatgggc gtattggaac cattctcaat ctgacgccag cctacccagc
    13561 tagtcaatca gaagcggaca tggctgctgc gcattttgca gaactttgga acaatgactt
    13621 gtttatggaa gctgctgttc atgggaaatt cccagaagaa ttggttgcgg tattgaaaaa
    13681 agatggggtt ttgtggcaat caacgccaga agaattggct cttattgctg agaatagagt
    13741 ggattatttg ggattgaatt tttaccaccc taagcgcgtg aaggctccgg atgtcattcc
    13801 agtgattagc ccatcttgga gtcctgaatg gtattatgat ccctacctga tgcctggccg
    13861 ccgcatgaac gtggataagg ggtgggagat ctatcctgag gctgtctatg atattgccat
    13921 caagatgcga gaccattacg acaatattcc ttggttctta tctgaaaatg gtgtagggat
    13981 ttcaggagaa gagcgttacc gtgatgaaac tggtcagatt caagatgatt atcgcatcca
    14041 atttttgaaa gaacatttga cctacctcca caaaggaata gaagcaggct cgaattgttt
    14101 tggataccat gtatggacgc caattgatgg ctggtcttgg ctcaatgcct ataaaaaccg
    14161 ctatggcctt gtggaaaata atatccatac ccaagtgcga cgacctaaag cttcagctta
    14221 ttggtttaaa aaagtagcta ctcataaccg cttgatttca ttagaagtaa tggaggagtt
    14281 tggaggctct gcttctcacc tcagtgattg aacgtgtgaa cgtctccttt gagacaagtg
    14341 aataatgatg ttaccaatga ttaaacaagg gcctttttcc tcatgttaag aggatcgagg
    14401 ctcttgtatt tctttggaag gtgttggtat ttgccgaact agatataagc gttctgtctg
    14461 gtttggcatc atctatccat cttgggtaat ttggctcttc aattctttag agtatcttgg
    14521 ctaaggatgc ttgtttttca tcttggtatt ttaggatttt ctttcatatt tttggaccag
    14581 ataaaagccc ctcatggttt ctagtgactg tttgttatgt cactgtccac gataagggga
    14641 ctatatgagt gagttattaa gtgaggcttt gcttattggc gataactagc atagcttcta
    14701 atagctcgag tattaactga tgaccaatgc ctttgacaga agcgtcagca acaacgacat
    14761 caacaaaggg accaggcatc aggctgcgtt catcagcaga gagtcattta ggcagaaagc
    14821 cagtatcgtt gtagctaatc agcaatcctt ttaggatgtc tttgtagatg tcagaggcga
    14881 ttagggacaa taggggataa gagggattta gcggtccatg gttaggcctc cttgtgttct
    14941 tggtaaaaat caatggcagc tccaagaaga ttggcttcgt ttttaaagtg acaaatggct
    15001 aattggggtc taaggtcgga gatttcgacg gcttggtaga gtttgtctag ttcagcttca
    15061 atcgctgaca gtagaaagtc agcttgggaa acaccacccc cgattaaaat cagttgagga
    15121 tcaaaggcgt gttgaatgtt aaaaataccg atggctaaac tttggagaaa gacctgcctt
    15181 tctttgagtg ctaggggatc tccttgttct gtgagggcaa ggacagcttt gccagtataa
    15241 tcttttccgt tattgacgat tgcactatag cgcttggcca tattcacaac agtgcctaat
    15301 tgactaaagg tttggtagcg gtcgttcatg atcatgaaac caaattcgcc cccaaataag
    15361 tgggcaccat ggtaaatctt gccatcaatg accaagcttc ctccaactcc agtaccaaga
    15421 acgagcatgg ctaggctact agcgcctttt cctgccccta aggtagcttc agctaaggcg
    15481 gcacaattgg catcattttc gatagaaata gggtaatgta gccgttcttc taaggcctct
    15541 tgtattttaa aatggtgaat gtagggaata gcgctggcgc cttcgataac ccccttttct
    15601 ttattgactg ccccaggtga actgatggca atacctgaga aatggtaagc agagtaacga
    15661 gcaacttctt ggtcgagtaa ttggtaaaac ttttccagac tagagggagt gggaaagctg
    15721 ctttgctggc ttaattggcc attgtgacag agggcaaatt taagggaagt gcctcctata
    15781 tcaatacata acaagctcat gaggtgttct cctttattat agtagaatag acgatcatgt
    15841 ctcatcttag tatgacagat ttaagcaaca atgaaaaggc tttctaagtg attctatact
    15901 ttgtgttatc atacctataa tttgttgctt tcaaataatg aaagcgcttg atatactgta
    15961 actataacgt gattaacaca aagggaggtt gggaaatgac aagacagacc aacaaaaaga
    16021 catccttttg gaaaaatgtg attaagtacc gggccttatt attaatggta ttaccaggtt
    16081 tcatctggtt catctttttc ttttatattc cagttttagc caatgtggtt gcttttaaag
    16141 attttcatta ttcagcaggg ggctttatgg aaagtttgaa ggagagccct tgggttggtt
    16201 tggctaactt caaatatctc tttgcttcca aagatgcttg gttgattacc agaaatacca
    16261 tcgcttacaa tgtgattttc ttactcttta atgttttctt tgcgattgct tttgccatta
    16321 tcatgagtga gttacgaaat aagagaacgg ttaaggtcta tcacaccatg tccttattgc
    16381 cttatttctt atcatgggtg gttattgaat actttgtttc tgccttttta aatacggata
    16441 aaggtttcat taatcagctc ttgactggaa gtggagcaga tccaatcaag tggtattcca
    16501 atcccacttg gtggcccttg attttactct ttatgagtgt ctggaaaggg ctaggctaca
    16561 atagcattat ctactatgct tcagtcaaag ggatttctga tacttattat gaagctgcta
    16621 tggtggatgg tgcaagcaaa tggcaacaaa ttaggaacat caccattcca caattattgc
    16681 caatgatgtc tatcctattg atcattaata ttggtaatat ttttaaatct gatttcggac
    16741 ttttctacgt tattcccaag aattcaggcc cactttatga cgtgaccagt gtgttagata
    16801 cctatgtcta caatgccttg actgctacag gagatattgg gatggcatcg gcagctagcc
    16861 tttatcagtc agtagttggg accagcatct tgttagtcac taatgcgatt gttcgtcgca
    16921 tggaccctga tgcagccttg ttttaggagg aaaacatgga gaaaaagaaa aaagtcgaaa
    16981 aggttaatgt tagaaccttt gatcgaaaaa ccaatgctat ctttaatatt ctgattggtc
    17041 tgtttgccat ctcttgtatc attcctttta tcttcgtgat tattatttcc ttcactgatg
    17101 aaagttactt gattaatcat gggtatagtt tttttccaga tgtctggtca actaaggctt
    17161 accagtatat ttttcaagga gccatgtccc atagaatcat gaggtcattt gggatatccg
    17221 tgtttattac agtggtggga acctttatta acacgaccat gacttcaacc tatgcttatg
    17281 cgatttcaag accttatttc ccatacagac gtttttttac tgtttatgca cttatcacca
    17341 tgctctttgc accagggatg gttgctaatt acttggtggt cagcaatctc cttcatttga
    17401 aggatacggt ttgggctttg attttaccaa tggctctggg cccatttggc atcttggtca
    17461 tgagaacgtt ctttaaaaag acagttccag atagcattat tgagtcggct cgtatggatg
    17521 gggctagtga atggatgatt tttatgaaaa ttgttctccc tttggctgtt ccagggattg
    17581 ctaccatcag tttattttct gccttaactt attggaatga ttggtttaac gccttgcttt
    17641 atgtgcaaag tgaaaacctc tacccaatgc agtacttact gatgaaaatt cagagcaacc
    17701 tacaggcctt ggcacaaaat gctggcatga gtgcacaaat ggcagatagc ttagcatcgc
    17761 tgccaaaaga atcagttcgt atggctatcg tggttattgc aaccttgccg attgccttga
    17821 cttacccatt cttccaaaag tactttgtcg gtggtttgac cattggtggg gtgaaggaat
    17881 aggacttaag gaactggtca caagaccaga ttttatctaa tcattagtaa caaaagaaaa
    17941 cattttttag gaggcttcac ttatgaaaaa gtggcaaaaa atcgtgtgtg tgactggaac
    18001 tgtgcttgca gcgtctagtt tagcagcctg cgaaagcaag tcagcatcaa aggatagtga
    18061 tgtcaaatta ttgatgtacc aagttggtga caaacctgat aacttcgatg aattgatgac
    18121 aattgctaac aagcgcatca aagaaaaaac aggtgcaacg gttgaccttc aatacatcgg
    18181 ttggggggac tgggatgata aaatgagtac catcattgcc tctggtgaaa actacgacat
    18241 tgcttttgcc aataattatg tggtcaatgc acaaaaaggt gcttttgctg atttgacaac
    18301 gttaatgcca aaatacgcta agaaaacgta taaaaactta gacccagcct atattaaagg
    18361 aaatactatt gacggtaaac tctatgcctt cccagtagat gccaacgttt atgcccaaca
    18421 gatgctttct ttcaataaag aactagtgga caaatatggc cttgacattt caaacattaa
    18481 gtcctatgca gatgctgaaa atgtcttgaa acaattccac gaaaaagaac caaatacagc
    18541 agcttttgct attggtcaag tctttagtat gtcaggtgac tatgactacc cattaaccaa
    18601 aacccaaccc tttgctgtga aaattgatga aggcaagcca accatcatta atcagtatga
    18661 agatgagtcc tttaaaaaca atctccgctt gatgcacaaa tggtataaag aaggtttgat
    18721 tccaacagat gcagcgacca atacagaagg ttatcccctt gaaggaaaca cttggtttat
    18781 gcgtgaagaa acccaaggtc ctatggacta tggcgatact atcttgacca atgctgcaag
    18841 aaaagacatt gtgtctcgtc cattgactaa accgctaaaa accacatcac aagcacaaat
    18901 ggcaaacttt gtggtatcaa gcgtatctaa aaacaaagaa aaagcagttg aagtcctttc
    18961 tcttcttaat agcgatcccg aattgttaaa tgggcttgtt tatggtgtcg aaggcaaagc
    19021 ttgggaaaaa attggcgaca agaaaatcaa actgctcgat ggctatcaac caaaaatgca
    19081 catgggtgct tggaatactg gtaacaataa aatcctttac actcaagaat ctgttactga
    19141 cgacatgatt gctaaacgtg accaatcaat caaggatgct aaagaatctc caatccttgg
    19201 tttcactgtt gacacaaaag ttatcaaaac ggaattgtca aatatttcaa atgtcatgaa
    19261 ccgatataaa gcaagtatca atactggtac agtggatcct gacgaagccc ttccaaaact
    19321 tcttgcagac ctcaaaggtg ctggttggga caaggtgcaa aaagaagttc aaaaacaatt
    19381 ggacaacttt gtagctaaag acaagtaagg cattcatttt cttgattata agttgagggc
    19441 tgggaaatct cagctctttt cttctgatga gtggaaaaaa cggatcatca aataagtgga
    19501 agttataaag ggagaaaaat taatggaaat aatgttacta ctcttagtaa agcggtttcc
    19561 aaaagcctat aaagtgtgct atattagaag agtctaaact attaatcaga gtaaaactaa
    19621 taccagcatc ttactggggg tgctaaaact agcctcttag ctgctggtcc ctgaaaccgc
    19681 tataagtgtt aacaagaaaa agaggactat catatgaatg gcattgaaaa aacctgcttt
    19741 ttaatttgga aaatgatcca attgaccctc atttttcatc tcttgtcctt agctggactg
    19801 attgtatttg gggtggggcc cgcctggcaa accattgtca ccctattttt aaaaacacct
    19861 caagaagaaa accactattc tttgaaaagg gctgttcaac tttggaaatc ttatttcaaa
    19921 gaagctaatc taagatttgg tctttttgcc ctgactttcc tttttttaac ctttaatttg
    19981 cattgggcag tacagtttcc atccttgttt tggtttaccg tgtctttctt gattgtaata
    20041 gccatggttt ggctaaccat gacctatctt tacatggttt tttatgcagt gagctatgag
    20101 attaaccttt ggaataatat gaaattagcc tttatcagcg tctttttaag tttcaaatcc
    20161 tttttactca tgctgagtgt tttgctggga attatcttag tgacttggca atacaaaggt
    20221 ctttatctct ttttaacctt cggagctcta gtcttttgct tggactttgt cactaaggct
    20281 aatcgtcgac tagtagatgg agtgattgat gagtgttaaa acattgggaa ggtatgtgac
    20341 taaccacttt aagcagggtt ttttgattaa tcgactgatg aaattatata gcctgctaat
    20401 tgtaagtttt ttcactttag cagctattgg cttgagcagt tattctatta gtagtactta
    20461 taaaagggtg gatgctgagg cgcagatgcg actggaggag actctaggta gattgcagtc
    20521 acaaaacgat attaccctat gggttttaga ccagttggtt ggccgttcag aagattacca
    20581 taatctctat caatacatga cgttaacccc aaaccaatat ttttcaaacg tttttgaaga
    20641 ctgggaaaaa ggaaaagaca cggtcctatt ttctgaagag gtgaggcgtc tttttgactt
    20701 gtaccctgat gtgacttcta tgaccctact gctagaggac agtagtgctt atctgtacgc
    20761 cgatagggtc attaagacgg gtcgtttgct ttatagcaag cctgaaaaag taaccggaaa
    20821 tgttttagtt cgctccattc gaaatccaga atcaggagat gtgacaggtc gtctttacct
    20881 gacctttgac aaaccaccga ctttggtaga gacacagcag gatcactatt tagctacttt
    20941 tgcttttgat tactatggtc gcaaactctt ccatcaagga ggtcggagat ttcctcattt
    21001 agaggctgag gttaaaaagg ctatcaaggc agatcgggca gctgatctta gtaatctcag
    21061 caaggcttat cggatgcagt acaatcgctc gggagacctc ttagcttatg tggctgtcag
    21121 aaaatcctat ttattagcgg aagctgtcag gacagttttt gtgtatggcc ttgtttctct
    21181 actcttagct tggctgttat tgcagttgct ctttagggtt ttccgaaatt atatccagca
    21241 ggtttctgaa attacggata ctgttgaaat ggttgcagca ggcgatttgt ctttaaccat
    21301 cgacaacagc cacatggaat tggaactgta tcatatctca gaagccatta atcagatgtt
    21361 ggccagcatt aaagcttata ttgacgaagt ttatgtgtta gaggtagagc aacgagatgc
    21421 ccaaatgaga gctctgcagt ctcaaatcaa ccctcatttt ttatacaaca cgttagagta
    21481 tattcggatg tacgccctta gttgtcaaca agaagaatta gcagatgtca tttatgcctt
    21541 tgcgagtctg cttcgcaaca atattagcca agataagatg accaccttaa aagaagaact
    21601 ggctttttgt gaaaaataca tttacctcta ccaaatgcgg tatccagata gcttcgctta
    21661 tcatgtaaag attgatgaga gtattgctga cttagccatt cctaaatttg tcattcaacc
    21721 tctcgttgaa aattattttg tacatgggat tgattatagt cgcaatgaca atgcactaag
    21781 catcaaggca ttagatgaga cggatcatct cttgattcag gtgcttgata atggacgtgg
    21841 tattagtcaa gagcgcttag cagatatgga aaaaaggctt caagagcacc aaacaacagg
    21901 caatagctct attggtttgc aaaatgttta cctccgtctt ttccatcatt ttcgagacag
    21961 ggtttcttgg tccatggcta aggagccaaa tggtggcttt atcattcaaa ttaggattag
    22021 aaaggatgct tgatgtataa ggtactatta gttgacgatg aatacatgat tttacaaggg
    22081 ctcaccatga ttattgattg gcaggcactt ggatttgaag tggttcaaac agcaagatca
    22141 ggcaaggaag ccttagccta tttgactcag tacccagtgg atgtcatgat ttcagatgtt
    22201 accatgcctg gaatgacagg actggattta atagaagcag ctaaaaccta tcatcctcag
    22261 ctacaaacct tgattttatc tggttatcaa gaattctcct atgtgcaaaa ggctatggaa
    22321 ttagaaacca aggggtattt gttaaaacct gtggataagg cagaattaca ggctaaaatg
    22381 aaacaattta aagactgctt ggatgcccag caggcagaat caatccggca agaagcctat
    22441 catgacagcc ttttgaccct ttggcttaca gatgaattga gtgagaaaga atttcagcag
    22501 ctaagtcaag gcttgccagc ggctgcttta actggtttta cagtgctgta tttggactgt
    22561 caagagtggc aagcagccat cgatgcttat tttgaacgag aaggtcagcc tttttacctc
    22621 aaaaaagaag aagataagaa ggtttatctg gctgtcctac ttggtaaaac tgatcaagcc
    22681 aaggcattta cctatgatct acaaaagcga ttctcaagaa acatgcatca acttattttg
    22741 ggagaaacag ttgatgactg ggaaaatgtt tatgaaagct acaatcaggt gcttaagagc
    22801 ctcttttaca attgtgaagt gtcaccaatt agagcaaaag ataagtccaa aattgaacta
    22861 ccagagtccc gtttgcagtt ctttgctttt aacaaggcgt tgatgattgg ggacgaacct
    22921 acaatcttgt ctaaattaga agctattttt gacgagatga agaccttgaa cttttcacca
    22981 gaggatgtga agcatgtttc gttcttgttg ttttctgaca tttaccgtca atttcccatt
    23041 ttagataaaa tgacttatct gtccatggta aaaactattc atgacagcca atccattgat
    23101 cgcattttga gggaactaaa aaaagtgttg gatgtcacca atcagaacaa ttcccctgaa
    23161 aaacgttatt cagatttagt tagtgaaacc attgattgca ttcgcaagga ataccatcaa
    23221 gaattaaccc ttaaagctat cgctgatagg ttacatgtca atggggttta tttagggcaa
    23281 tgctttaaaa atgaaaccga gcgtagtttt acccagtact taaatcatgt taggattcaa
    23341 aaagcgcaac agttattgct ttacaccaac caatccatca atgaaattgc ttatgaaaca
    23401 ggttacaata ccaatcatta ttttatcaag atgtttaaaa agttgaatgg tttatcgcca
    23461 aaagagttca gagatcgtta caaggacaat taccaagcca tcaagggcga ccagtaacgt
    23521 caaacaggag attgatatga catcagatag caaggagcag acagtgactg gctaccaata
    23581 ccactatatt gatcaagaag gaagaaagca gccctttaat caaggctggc gttttcttat
    23641 ggcagatgtg gcgtgtgctc aggacccttc ttttgatgat tcgaactggc aggtgattca
    23701 tttaccacat gatttcagtc ttaagcagcc ttacacaaga aatggtgaag ctgaaagtgc
    23761 ttataaatta ggtggtgtcg gttggtatcg gcattatctc gtgttagatg aggttttagc
    23821 tggttgtcat gttgccatta cttttgaggg ttcctatatg gaaacggaaa tttatgttaa
    23881 tgggcaattc attggcaaac acttaaatgg ctatcaggaa tttacctatg atatctctga
    23941 tgttgtgact tttggagctg aaaatcttct ggctgttcgg gttgaaaaca aggttcccag
    24001 ttctcgttgg tattcaggca gtggtcttta tcgtgaagtg agtttgtctg ttcttcccca
    24061 gcttcatttt gtggcagacc aggtagcaat gaccttggct gatactgctg tgcaggagaa
    24121 agggcaacag aaagttgatt tacgctttgc ccttaatcag tctattcaga cttgccacta
    24181 ccaattgagc ctctgtttat gggaacaatc acattgctca aaagacaaaa aactccttta
    24241 tcaagaaaca gaagtgcctc tagctgattt ggctttccaa agacagtatg gtcttacact
    24301 gtctttggaa gaactccaat tgtggtcacc agataatcct cacctctacg atttagaact
    24361 cactctttac tatcaaggtc aggtcattga ttgcttttgc cttgaaactg gttttcgtca
    24421 gctgactttt acggccaatc aggggctttt tgtgaatggc agagctgtca aattaaaggg
    24481 agtttgtttg catcatgacc aaggaggcct aggagcttgt gcttacgaag atgccctagc
    24541 cagacaatta gtcctgttga aagacatggg ggctaatacc attcgtagca cccataaccc
    24601 aagtagtccc aaacttaggc aactagccaa tcgtctcggc ttttttgtga ttgaagaagc
    24661 ctttgacacc tggacctatg ccaaaaatgg aaacgttaat gacttttcaa actatttcca
    24721 tcagactatc ggaactgaaa atgcaagcta tcttcaaaga gtgaggtcac ctgaaacgag
    24781 ctgggcccag tatagtattg aggccatggt ctggtctgcc aagaatgacc cgtcagtgtt
    24841 gatgtggtcg attggtaatg aattgatgga aggtttttca gccgatgtca gtcattaccc
    24901 agagctgaca agacaaatgt gccaatggat tgctgctatt gacacctcac gtcccattac
    24961 ctttggggac aataaattaa aagaagctga cttttgctgg catgaggaag tgtcgcaaat
    25021 ggcaactctt cttagtcaat tagaccatcc ccagggactc attgggttaa actatgctaa
    25081 tggaaaagac tatgataagc ttcatgagga gcactctgat tggctgttgt atggttctga
    25141 aacagcctca gctattacca gcagggctta ttataaagag acaaaaaaag ttcttgactc
    25201 cggttatcac ctaacctctt atgatcatgc taaggtcgat tggggtgcct tcgctagcca
    25261 ggcttggtat gataccatta cccgtgattt tgttgctggc gaatgcgttt ggacaggctt
    25321 tgattattta ggagaaccta ccccctggaa caagatcgac agcggtgttg taggcctttg
    25381 gccttctcct aaaaatgcct actttggcat tttagacacg gcaggctttc caaaagatag
    25441 ctattatttt taccaaagtc agtgggcgca ggggcagacc accttgcacc tgttaccagt
    25501 ctggcagaag gaccagcttt gtttcgatga gcagggattg gtggaggttg tggtttatag
    25561 caatgctgcc agtgtgcaac tgatgtttga agatgagcag ggcaacttaa cagattatgg
    25621 aaggaaggca tttcatactt atagcatgcc aacgggacac acttatcagc tttaccaagg
    25681 agctgacgct gctaagaatc ctcacgaaaa tctttacctg acttggcgag tgccctatca
    25741 aaaagggttg ctaagggcag tggcctacga catttctggt aaaagcattc caaaaaccag
    25801 tggacgttct caggttagaa cctatggttc agtggcaaag ctatcttgga aagcctttga
    25861 agcacctatt gacgctcctt gggaattgct ttatctggat ttatcacttt tggatagcca
    25921 aggtgaattg gtcagccatg ctcaagattg gctaaaggtt caagtagaag gaccagcccg
    25981 tttgttggct cttgataatg ggaatccgac tgaccacacc ccttatcagg agcctctacg
    26041 ccaggcatat gggggaaaat tattagccat tttagccctc actggagagg cgggacacat
    26101 taaggtcacg gcaaaagcct cgcagcaact tagcagtgtt tttcagacac aagtagcctg
    26161 ccgtgccccc aaagaacact tagtgacact acctttagag aaatatcagt ttaaaaagag
    26221 ccgactgaca agtcaacaag aaattggtca atcttgtcta aagaccacac aattcctttc
    26281 tgttttggag aacaaagaca cccagcaaaa agcaggtaag gctagcacac ctcacattct
    26341 tatcaccagt taccagcact atttacctct gcccttgcag gtttgttctc aggcatttga
    26401 ttttaaaaaa ggcgatgata tcttcttgcc tcagtggctc caagtcaaag atgcccaagg
    26461 ttcttttgtg aaaaaagctt ttccaatgac atggtaccta aaagagaaaa tctttgccaa
    26521 gcctattctt gtcacaggct atgtttcttg ttttgggcaa tcaataccgg ttgaggcaag
    26581 gcttaaccta gcacaagcta gcaaaagacg gcaccaggat ctcagtttag tcgccaagca
    26641 atccctggcc gcaagtcaaa aaaggctaac ttattgctac caatatgata cggtgcaagc
    26701 cataggagcc attagcttgc aaaatcacac aggcacatct cttagtgttt ctgtggcaat
    26761 cagttatggt agtcagagct ctattaagca agaaaccttg atgctagctg atagccactt
    26821 gagccagtta gaagaggtta ttttcttcga tgatattttg actgttttgt atctggcagt
    26881 gacccttgaa gtcattgaag gacctgacct aactgaagac agtattcaaa ttggcctttg
    26941 ggatttagca tgaagcatga gtaaaagaag acttctttgg caccaggtct gatgaattct
    27001 gtaaaataag gtataataaa aaacaaatag gcgtccttta ttacgtgaaa ggcgccttta
    27061 caaggttgaa atggaaagtg agatttctaa atgtcagaac gtttatcagg ccacaccctg
    27121 ttggtctctt tgcttgctac ccctattcgt catagtttgt ctcccaaaat gcacaatgaa
    27181 gcctatgcta aactggggct ggattatgcc taccttgctt ttgaagtagg gacagagcaa
    27241 ttagcagatg ccgtgcaagg gattcgtgcc ttaggaattc gtggctccaa tgtgtctatg
    27301 ccaaataaag aagctatttt acccttattg gatgacttgt ccccagctgc tgagttggtc
    27361 ggtgcagtca atacggttgt caataaggat ggtaaaggac atctcgtggg gcatattaca
    27421 gacggtatag gagcgctcag agccttggct gacgaaggag tgtcggtaaa gaacaaaatc
    27481 attaccctag caggagttgg tggggctggg aaagctatcg ctgtccagct cgcttttgac
    27541 ggcgccaaag aggttcgttt gtttaaccga caagctacac gtctaagtag cgttcaaaag
    27601 cttgtgacaa aactgaacca gctaacaagg actaaagtaa cccttcaaga cttggaagat
    27661 cagactgcct ttaaggaggc catcagggaa tctcatctat ttattgatgc tacaagtgta
    27721 ggaatgaagc ctttagaaaa tctaagtttg attaccgacc ccgagctcat tcgcccagac
    27781 ttggtggtct ttgacatcgt gtacagccca gcagaaacca agttactagc ctttgcccgt
    27841 caacatggcg cccaaaaagt cattaatggg ctagggatgg tgctttatca aggagcagaa
    27901 gcttttaaat taatcactgg tcaagacatg ccagttgacg ctattaaacc tcttttaggt
    27961 gatgagtaac actttttaag taagcttaat tatgatatat taataagaga tggagcagtc
    28021 atcatgggct gctaaaattc tttttgcgag agctgttttt aagagcaaaa agcttatttg
    28081 aagagcctta tccctaacgt gatacaagtc atagttcctt tgaggtctgc cagataacct
    28141 accgtttttt tagaaaagaa gctcttataa aaggaaaagt tcaatgaata aaggagaata
    28201 gcaatggtaa caaaggaagt tgggcatgac tttttagcac gtctaggaaa aaaacgctta
    28261 agacctggcg gtgttgaggc gacaaactgg ttgattgaac aaggacaatt ctctcaggat
    28321 tgtcacgttt tagaggttgc ctgcaatcgc tgcacgacag caatagagtt agccaaaacc
    28381 ttcggttgta agattgatgc cgttgactta aaccccaagg ttgtcaaaga agcacaagaa
    28441 agggttgctg ttgaggggtt aacccgtcac attacagtat cccaagccaa tgctttatca
    28501 ctaccatttc cagataacca ttttgatatt gtgattaatg aagccatgtt aaccatgttg
    28561 aacgcccaag ccaaggagaa ggcactcaat gaatattggc gtgtgttaaa accaggcggg
    28621 cgacttttga cacatgacgt agcttatgaa gatccaaaaa caagacaagt acttgacgag
    28681 ttacgtcaaa cgattcatgt caatgttgct cccttgtcac taacaggttg gcaagcctta
    28741 tatcaagaac acggtttttc tcaagtgact tatcaccatg gaaaaatgtc tttgatgaca
    28801 cctcgtggaa tgattaagga tgaaggtctt atgaacaccc tgaacattat gagacgaggc
    28861 cttaagaaag agaacagaca acagttttta aagatgcgtc gtttttttac cagaacaggc
    28921 aaaaatctct gctatattgc tgtaaaaagt gtaaaataaa ccttagacca acctgtccat
    28981 acaactaaac agaccataga ggagttcgaa gatgtcttat atcaataata ttgagcacgc
    29041 gaaggttctt gatttgacgc aagaagtaat gattgagcaa gatcaaatgt taagtagaac
    29101 actagtccaa aggcaagacc taggaataac agttttttcc ttagataagg gccaagaaat
    29161 tgggcgacac tcatcaccag gagatgccat ggttactatc ttaagtggct tagcagaaat
    29221 caccattgat caagagacct accgggttgc tgaaggtcaa accattgtga tgccagctgg
    29281 gattcctcat gccttatatg cagtagaagc ctttcaaatg cttttagtag tagtaaaacc
    29341 ggaggcttaa catgattgaa aatctctctc aattggtgca atatcatgat catcaggtgg
    29401 ctagccgatc cttgaaccgt ctactgggat tatctcaatc tattgtttta tatgccatgg
    29461 cccaaggaga aagcattagt caagagacta gtccaagaga taaagtaata cttgttttag
    29521 aaggtcagct cattttcgat ttagaggatc aaaaacaggt cctaactcaa gaaagtctca
    29581 tagccatacc tgcccaaaaa gtccatcatt tagaagctaa aaccgattgt aaactattac
    29641 aagtgctttt agattaaggg cttattgtca actgtattgg gtggcctatg gaaaagcaaa
    29701 agagaaggtg acgctcatct tctcttttta cgtattcaaa gcgatgacaa tacgaatttt
    29761 aaagcttggc tttctcatct ccagattaag ccctttagct tggtttattt tagaattcac
    29821 taaaaaaacc ttaatgagtt tcctatctcc ttataggttt ctcattaagg ctttttagac
    29881 gaaataattg aacgacaggc aaaagaaaga tctttttacg agtgataccg ttctcctata
    29941 gttccataaa tcctcttttt gatgttgctg ttagttattc ttagctaaaa gttatattgt
    30001 tatcaagact tgtcttgtag taactgtttt aggagttcca ggataccgtt attctcttag
    30061 caagcttaac tagctagagt ggagtcacta tttataataa actgtcgagc ttctcgacaa
    30121 attggtgatc gtctttgtta atggctaggg tggtaaaacc ggtttctgtg ggtaatataa
    30181 agataatatg ttgctcagaa ttcttcttat ctgttttaaa gacgtcaaag agggatgtcg
    30241 cagagacatc agctctttca agtgttgttg gtaactggta acgttcaaaa acttgaagga
    30301 ggctatccaa gtcctctttt ggcaagagcc ctttggaaac agccagttta gcatcaacca
    30361 ccataccgat agcaatggct tcaccgtgat ggtaaaaatc atggtggcag agcgattcaa
    30421 tcgcgtggcc caaggtatgc ccaaaattta aagatatgcg caaaccattt tcaaattcat
    30481 cttgttcaac aatccgtttt ttattggaaa tggattggta aatcagacgt tcaagtccct
    30541 gcttatcggt ttctttttga aaatcacgta actgctgaaa aagcggttta tcatgaatga
    30601 agccgatttt gagcatctca ctgatgccgc aggagaattc ccgttgcggt aaggtctcca
    30661 aaaaggtggt tgaaataatg atagcttctg gagggtaaat gctaccaatc atattggtta
    30721 gacctttaaa atggactcca actttgcccc cgatactgct atccacctga ctaagtaaag
    30781 tcgttgggat ttgaatgtag ggaataccac ggtaataggt tgcagcgaca aaaccaccca
    30841 gatccccaac aacaccacca ccaatagtaa caatcatatc ttttttggaa aaattttcag
    30901 cgatgagctg gtcgtagata gcactgacgc gttccacgga tttggattga cctcccgggg
    30961 ggcagacatg gacaaaagcg ttgtattgct gagcaaattc ttcaaagaga gtctgataca
    31021 agtggtagac cgtttgatcg gtgataaaca agagtttacg ctgcttgcgc tcaccaaggc
    31081 aatctgctaa ggtttttaaa acatggtcgg taaacaggat atcataatcc ttgacccgag
    31141 aatggacatg aagtgtttgt ggcataagca ctcctttcat cagtactagg taacagagat
    31201 aacgcagtga tatttagagc ttaatcttgc caaagttcct gccccaactg ttctaattgc
    31261 ttataatcaa tttgctgggc agcatctgac agcgcatggt cgggatcagg atgaacctcc
    31321 atcatgatgc cattggcacc gacagccttc gctatcttag cagcaggtaa gagtaaatct
    31381 cgtctgcctg tcgaatgaga cacgtccaca ataatcggta aatctgtctt ttgttgaata
    31441 atagggactg ccataatatc aagcatattt ctagtctcca catcgtagcc acgaacgcca
    31501 cgttcgcata agataatgtt agattttcca gtgtcttgta agtaggaaag ggcgcccaaa
    31561 tattcctcga tagtagccat caagcctcgt ttaaacaaaa taggcttatc gatgtgtgac
    31621 aaggttttta aaaattcaaa attttgcatg ttgcgggcac caacctgaat gacatcgaga
    31681 tagtcatagg cttcttctaa ttggcgctcg gacatgattt cactgaccga tagtaagcca
    31741 aattcctgac aaacctcatg caagtaacga attccttgca ggccaaggcc ttgaaaagaa
    31801 gcagcagatg ttcttggttt ataggcgcct cctctaaaat agttgtaacc aagttttttg
    31861 gcacttgaag ctgctaatct aatgtgatca taagattcaa tggaacaagg tccaacaata
    31921 aaattattct tagaacaagt cttattttga aagtcagaca taatgtcaat cattcgtttg
    31981 attcctttac taattctgta tggcgtgctc tatgggataa cgtcttattt aggaatacaa
    32041 aatctcgttg ttatccatga agcaccctta gcctgtgaaa tgataccata aacaagatga
    32101 aatagcaagt aaaccctaga ttgtctatgt tcttagtcat ttttattaaa aaaggcttgc
    32161 tagctataaa aaaaatactg ccctaaatct tattaggcca gtatttttta tagatgccac
    32221 caccgagaat cgaactcgga acgaagcatt accattgctt tattatacca tttaactaca
    32281 gcggctacct ttttataata ctataagtta ttaattgatg caagcttttc ttaaaaatat
    32341 ttccttaatt gtttatcatc aaaatgaggg taccagttat taataacatg gcacaagagg
    32401 cctgccttat ggtataatgg taaagatgat ttcagaaaga ggaagctaag catgtcttat
    32461 gaaaaagaat ttttaaaaga ttttgaagac tgggttaaaa ctcagattca agtcaatcag
    32521 ctagccatgg caaccagtca agaagttgcc caagaagatg gcgatgaaag ggctaaagat
    32581 gcctttattc gttatgaaag taagttagac gcctacgaat ttttactagg taaatttgac
    32641 aattataaaa atggtaaagc ctttcacgat attccagatg agttatttgg agcaaggcat
    32701 tattaaggac aaggagacac gaaatagtgg caaaacaaaa aaatcgtaaa aaagcattga
    32761 agttagaaat gaagcgtaat ggcttgttaa aaaaagcagg tcaagttttt gataaggcag
    32821 ttgaaagtgt tgaaacagct gtggataaaa ccatttctgc tggtaaaaat cttgtggaaa
    32881 aaggtagcca aacggttgaa aacctgacag caagcaagga aagacttact cttgatgagt
    32941 ttgcagggca gccagttgta gctggtatcc gctctgacct tgtggaaacc ctatatgcag
    33001 aaggtatcca ttcagcgcaa gcttttaagg agtggacaga aaaagacctc cttgctctta
    33061 agggcattgg tccagcaacg gttaaaaaat tggtcgaaaa tggcgcaagc tttaaaaaat
    33121 agtcatcttc tcgttgctta atggctataa atttgttaga atattagcaa tcagaggtgc
    33181 attgagttgg tctgttacag agagcggtgg tgttgagaaa tccgcacaga tgtcaaggct
    33241 agtagctgag gattagaaat cagatatgaa aagtagcaga cccattttat ggtctgaaac
    33301 agtggtggta ccgcggaaat cgtaacacga aattcgtccc tgtctaggtt atctaggcag
    33361 ggattatttg gtttcatttg aaagaagatg atggcttatt gttaaaatgt tgttagaagt
    33421 atataataga aaaactttgc tcaaagtgga aacagaacgg ctgctattac gtcaacgaaa
    33481 attggaggac gccgaggcca tatttgcctt tgctaaactg gcggaggtta gttatcctgc
    33541 tggttttccg cctgttaaaa gcttagcaga tgaaatcacc taccttcaag acatttatcc
    33601 cgccaatctt gaaaaagagg gactaccatc aagctatggt attaccctaa aaggcgatga
    33661 caaagtgatt ggttcaattg actttaatca tcgacgggca gatgatgttt ttgagattgg
    33721 ctacctgctc catccagact attggggaca gggcattgtc ccagaagcgg ctgccgccct
    33781 gattgagatt ggctttaccc tgatcgattt gcataaaatt gagctgggct gctacgacta
    33841 caacaagcaa agtcaggcag tcgctcgcaa actaggcttt accttggaag ccaatgcccg
    33901 tgaccgtaag gacgttcaag gtcgccgctg tggcgacatg cgttttgggt tactgagaag
    33961 tgagtgggag gagcagaaac aaaaatgaac cttatcatca ttggtgctca agcgtcgggc
    34021 aagatgacca ttgggcaaga agttgccagg cagacaggca tgactttgtt tcataatcac
    34081 gattctattg attttgtttt acggtttatg ccttggtctc aagagagcac tgccttgatt
    34141 gaacgtatcc gttttgcttt ttttgaaacc ttgatccaaa tgatgtagca atgcttgaaa
    34201 agactcaggt tgtttttcag tcttatgacc aagaggttct ctttgtcgaa ttaaaaacag
    34261 atatagagga acgtcttaaa cgcaatcgca cagaaaatcg tctcaaacat aaacctctta
    34321 aacgcaacat cgagtggtca gaacaagata ttcaatccac gatggcatat gctgttttta
    34381 atccagaaga accacccaaa acgctcacgc attaccaaaa aatcaataat acccatctca
    34441 ccgctgctga aacagcgcag cttattatcc aaaaaatgac tcatatcaag gagaactaag
    34501 atgacagaac tatcacctaa atacaatcct gccgaggttg aggcaggtcg ctatcaaaaa
    34561 tggcttgatg cagatgtttt taagccatca ggagaccaaa aagcaaaacc gtattctatc
    34621 gtgattccac cgccaaatgt gactggtaag ttgcacttgg gacatgcttg ggatacgacg
    34681 cttcaagata ttatcattcg tcaaaaacgc atgcagggct ttgatacgct ttggttgcca
    34741 gggatggacc atgcagggat tgcgacacag gctaaagtcg aagaacgttt gcgtggtcaa
    34801 ggcatcaccc gttatgattt gggtcgtgaa aaattcttgg acaaggtctg ggagtggaaa
    34861 gacgaatatg ccactacgat taaagaacag tggggcaaaa tgggtctttc tgtggactac
    34921 agccgtgagc gcttcaccct tgatgagggc ttgtcaaaag cagttcgcaa ggtttttgtt
    34981 gacctctaca aaaaaggctg gatttaccgt ggtgaattca tcatcaactg ggatcctgct
    35041 gccagaactg ccctttctga catcgaggtt atccacaagg atgttgaggg agctttctac
    35101 cacatgaact atatgttgga agatggctca cgcgcccttc aagtggcaac aacgcgacca
    35161 gaaaccatgt ttggagacgt tgccgttgcc gtaaacccag aagatcctcg ttacaaagat
    35221 ttgattggta aacatgttat tttaccaatc gtgaataaat tgattccaat cgtgggagac
    35281 gagcatgccg accctgaatt tgggactgga gttgtgaaaa tcacgcctgc tcatgaccct
    35341 aatgactttg aggttggtca acgccataat ctgccacaag tgaatgtcat gaatgacgat
    35401 ggcaccatga atgagttagc tggcgacttt gcaggcatgg accgttttga agctcgtcaa
    35461 gctaccgttg ctaaacttga agaacttggt gccctagtaa acatcgaaaa acgtgttcac
    35521 tcagtaggtc actcagaacg ttctggtgca gtcgttgagc ctcgtctatc cacccaatgg
    35581 tttgtaaaaa tggatgagct tgctaaacaa gctatggaca accaagaaac agatgaccga
    35641 gtagatttct acccaccacg ctttaatgat accttccttc aatggatgga aaatgtccat
    35701 gactgggtaa tctctcgcca attatggtgg ggtcaccaaa ttcctgcttg gtacaatgca
    35761 gaaggtgaga tttacgttgg cgaagaagca ccagaaggtg atggctggac tcaagatgaa
    35821 gatgttcttg acacctggtt ctcatctgct ttatggccgt tctcaactat ggggtggcct
    35881 gacacagatg tagaagattt caaacgttat ttcccaacct caaccttagt aacaggttat
    35941 gacatcattt tcttctgggt gtcacgtatg attttccaat cgcttgaatt taccgggcgt
    36001 cagccattcc aaaatgtcct gattcacggt cttattcgtg acgaagaagg acgcaaaatg
    36061 tctaaatcat tggggaacgg gattgatccg atggatgtca ttgagaaata cggtgccgat
    36121 agcttacgtt ggttcctctc aaacggctct gccccaggac aagacgtgcg tttctcatac
    36181 gaaaaaatgg acgcctcttg gaatttcatt aataaaattt ggaacatttc tcgctatatc
    36241 ctcatgaata atgaagggtt gaccttggaa gaagctgaaa gtaatgtggc taaggtagct
    36301 gcctcagaag ctggaaatgt gactgaccag tggattctcc acaacctcaa tgaaaccatc
    36361 gctaaagtga cagaaaactt tgacaagttt gagtttggtg tggcaggaca cattctttac
    36421 aacttcatct gggaagaatt tgccaactgg tatgtggaat tgaccaagga agtgctgtat
    36481 agcgacaacg aagctgagaa agttatcacg cgctctgtcc ttctttatac tttggacaaa
    36541 atcttgcgtc tccttcaccc aatcatgcca tttgtaaccg aagaaatcta tgcccaatat
    36601 gcccaaggtt ctattgtgac cgcagcatac cctacggtta ctcctgcttt tgaaaatgag
    36661 gctgcgcata aaggtgtgga aagtttgaaa gacctgattc gtgcagttcg taatgcgcgc
    36721 gctgaagtta acgtggcacc atcaaaacca atcacaattt tggtgaagac agcagatagt
    36781 gagttggaag acttcttcac cagcaacgtg aactacatca aacgcttcac taaccctgaa
    36841 aaattagaaa tcagctcagc cattgctgcg ccagaactgg ctatgaccag catcatcaca
    36901 ggtgctgaaa tctacttgcc actagcagat ttgcttaacg tggaagaaga actcgctcgc
    36961 ctagataaag aactggctaa atggcaaaaa gaactggaca tggtcggcaa aaaactcgga
    37021 aacgaacgct ttgtagccaa cgccaaacca gaagtcgtcc aaaaagaaaa agacaaacaa
    37081 gctgactacc aagctaaata cgacgcaacc caagaacgga ttgcagagat gaagaaaatt
    37141 aaatcatagt gtttagaacg cagttgaaaa actgtgttct tttcttacta atagagatat
    37201 tagattgaaa tttaattatg agaaaacgct ttctttattt aaagagttat gttacaatac
    37261 tattacaatc atcgtacaaa tagtgttatt ttgagaggca tatgagaatg attttagcac
    37321 actatgactg taaaaaagat aaaaagcaat ctttagatga gcatttatgg catgtggcct
    37381 gttctagtcg acaggaagca tctataattg gtcaaggaga tgtgcttttt ttaattggtc
    37441 tttaccacga cctgggtaaa gctgatcgaa cctttcaaga taaattatta aataatccaa
    37501 atcggcatgt tgatcactct tatgcagggg caaaatactt atgttctatt attgggcctc
    37561 atctaaaaaa ccgaggggtt gataaaaatg agagaatgac attcaacgaa atggtggggt
    37621 atgtcatctc tgctcatcat gggatgtatg atttatgcta ctattttgac gatgctgaat
    37681 attatggctt taataagttt aaaaatcgta tcaatagaga cttagatggt tatcactatc
    37741 atgaagatat taaagggtac gctctaaaat tagaaaaaaa attatgtgat tatggctaca
    37801 aagatttaag ggagcttatt gataaagctt ttgataatta ccaacaagcc atgtcttcct
    37861 taaactggca agataagagt gagtgggatt attatcagtc ttgtatggtg agactttact
    37921 tgtcactctt aaaaaacgct gatattttgg acacagtaaa tgcctatggc cttaagataa
    37981 gtcctatgga taaaacagag cgatcctttc taaaacactc ctatttagcg gccattgaac
    38041 aaaaatatgc tagctttgga cagccaaaca atcagttgaa cactattcgg acagaaatcg
    38101 ctgagcgtgt taaagaaaga ggtaaacgag attccaaggg gatttatcgc ttagatttac
    38161 cgacaggagc tggcaagact aatcttagta tgcgttatgc gtttcaccaa ttagttcatc
    38221 acgacaaatc aaggtttttt tacataacgc cctttctttc ggttcttgaa caaaatgctt
    38281 ccgaaattag aaaagttaca ggtgaccttg gcgtcctaga acaccattcc aatgtggtga
    38341 aacaggctaa tgaagatgat gatgacaagg acagtttatt gtcagcttat cttagtgata
    38401 gctgggacag tcaagtagtc ttgacttcta tggttcaatt tttccaaaca cttttcaaaa
    38461 caaaatcagc taatctgaga cgtttttcaa gtttgattaa tagtgttgtg attctagatg
    38521 aagttcaatc cctgcctatt gaagtcacca ctttgtttaa tttaacgatg aattttttaa
    38581 ataaagttat ggatacaacc atcgttcttt gcacagcaac acaacctgct tatgattctt
    38641 cagagattga ccatcgtatc tgttatggag ggaacttggg agaattagct gaaatcgttg
    38701 agttaacgat tgaagaaaga cagatttttt caaggacaga gcttagaaaa tttgatgata
    38761 gtgatcagaa agttcacttg actgatgtta ttaaccttat tctaggtgag gaaaactcag
    38821 ttcttgctat ttttaatacg aaaaaaacgg ttcataactg ctatactatg ctaaaagaca
    38881 tgactgatag accggtctat cagctttcga caaatatgtg tgcgcagcat agacttgact
    38941 tgattgctaa gatcaaaacg gagttacaaa ataatatccc tattatttgt attagtacgc
    39001 aattaattga agcaggtgta gatgttgatt ttcatcgcgt cattcgttcc tactcaggga
    39061 ttgattctat tgttcaggct gctggacggt gtaaccgaga aggcaaacga gataaagggc
    39121 aagtcactct tgtcaatctg accaatgaag aggaaaatat ttctaggctg acagaaataa
    39181 aagctaaaaa agaagccaca gaatctattc ttcataagat tgggtctcca attgatatct
    39241 caactttaaa ccgtgacttt tttgagtatt attatgccaa taatcaggga ctgatggatt
    39301 atcctttgga agacaaccta tcaatctacg actatttaag ccttaatatt tatcagacgg
    39361 caaataaaaa gttcaaaggt aagttaaaac aagcttttaa aacagcagga gccaaaatga
    39421 acctcatcaa taatgacatg ataggaattc ttgtatctta tggcgaagct gagaaaaaat
    39481 tggcttattt agaagaatta ggtgtgtcac attttttatc agcaaaagat tatcaaacga
    39541 taaaatcatt actaaaagag ttacaacctt ttacggttaa tgtccgcgag aacgatcctc
    39601 tccttgatgc aacaaaatct tttctaaatg gtcaggttct ggttttgacg tcggagtatt
    39661 atgacacaga aagaggagtt aaatacgatt cagctaactt ttacttctaa ctcaaaacga
    39721 aagcagatta acgaaaggtt gttagaggac cttgttaacc tgccaatcat cattaataat
    39781 tattatcaat ttagactatt taataaaatt agattacaaa aaaacagaag gaggaaagta
    39841 gcttgtacag atctagagac ttctacgtga gagtaagtgg tcagcgggct ctttttacaa
    39901 atccagccac aaaaggggga tcggaacggt catcctattc ggttccgact agacaggcac
    39961 tgaatggtat cgttgatgcc atctattata agccaacctt tactaatatc gtcacagagg
    40021 ttaaggttat taaccagatt caaaccgaat tacagggtgt cagggctctg ttacatgatt
    40081 atagtgcaga tttaagttat gtatcctatt tgagtgatgt tgtttatcta atcaaatttc
    40141 attttgtttg gaatgaagat agaaaagatt tgaactcaga tagacttcca gctaaacatg
    40201 aagccattat ggagcgttct attcgtaaag ggggacgtcg agatgtgttt ttgggtacaa
    40261 gagaatgttt agggcttgta gatgatatca gccaagaaga gtatgagact actgtgtcgt
    40321 attataatgg tgtcaatatc gacttgggaa tcatgttcca ttcctttgcc tatccgaagg
    40381 acaaaaagac accattaaaa tcatacttta caaagactgt gatgaaaaat ggagtcatta
    40441 cgtttaaagc acagtctgaa tgcgatattg ttaacacgct ttctagttat gcttttaaag
    40501 caccagagga gataaaatcg gttaacgatg aatgcatgga gtatgatgcc atggagaaag
    40561 gagaaaactg atggattttt ttacttctct cttgaagact tatgaaaaag cagagctagc
    40621 agacttggtt gatcaccaaa aaagaagtaa tgagccggtt ttactgccga tttatcatac
    40681 gagtttaaag tcaaatggca aaaatatcat ttcagtgaaa cttgacaaag atggccagtt
    40741 tcacaaggca gaatttatgg cagataagca aatgattatt tttcctgtaa cggctgattc
    40801 tgttgctagg tcaggtagtc atcctgcacc gcatccccta gtcgataaat ttgcttatta
    40861 tagtgctgaa atggggcaga ctcagtatga ttcttttcat aagcaactga ataactggat
    40921 tgattattgt gaggagggtg atgtcaagaa atttttaacc tttgttcagc agttcatttt
    40981 gaagccagaa tttctaacat tgattcttga ttctttaatt ggtcctgatt atcaacataa
    41041 tcaattaaaa gtcacatttt gtgatgccac tggaaaagaa aaattaattg atttatcagc
    41101 ttgcttttta gaattttcaa ttgatcagtt ccagggcttt aaaaatgaat cggtttcgac
    41161 atttaaagcc ttacaccaat cctatatttc ttttgttgaa gccaagcgtg aaaatctcgg
    41221 tatttgtaat attagtggac gagaggaaca gcttaccgat aagcatagag gtttgatggg
    41281 gaatgctaaa atcatctctg ttagtaataa aagagaagct tataaaggac gttttagaga
    41341 acgcgaagac gtttttagtg ttggctatga aacttccgaa aagattcatt taatgctcaa
    41401 gtacctttta ggaaataaaa ataccagtac ttggttaggg tcttctcaat atttaatcaa
    41461 ctggttcagc gatgatttaa caaatgatag tcggttggat attgtatcac caatctttga
    41521 tgatggactt gaagaagatg atgatgacga tacgccacct gttataacat tagcaactga
    41581 agacaataaa agaattggta aatcattcat caagggacaa aaattatttg ctaatgatgc
    41641 cacttactac gttgctattt tgaataaaac cagcaatggg cggattgctt taaaatattt
    41701 tcgtcagctt caagcgtccc aattactcac caatcttaac aagtggcagg aaacatacag
    41761 ttgggagtcg cgatctaagt ttgggaaaag tcgcttaaga acccctactt ttcatgacat
    41821 ccttaatgtg tcctacgggg ttgataggga tcgcttcctt gaattagata atgataactt
    41881 caaaagtgat caaattcaaa agttagtggc aagtttgatt gatggtaaac cgatgccaca
    41941 gtccattgtc aaaaagttag gtaacaatgt taaagaacga catcgttacc gtaagcactg
    42001 gtatcaagtt gagcaggtct gcttagcaat tttacacaaa caaaatgggg aggaattttc
    42061 accgatgcta gatcatacca atcaaaatcg ttcctatctt tttggacgat tattagcaat
    42121 ttttgaatta atcgagacct tgcgttatgg cttggatgga aacaataacg accgtattac
    42181 caatgctgaa cgttattgga cagcctatac tggacaacca acaaaattga tgatgttatt
    42241 ggaaaataaa attaagcctt acgaagaacc attgaaatta aatcgtcgtg gcagttggat
    42301 gaaattagaa aaagaaaaag aagagatttt agaactgtta aatcctctgt tagaaacaga
    42361 aacaatggaa aaacccttag attaccgctt tatttttggg tattatgctg agaaaaacta
    42421 ttactataca aaacaaaaca cggaagtaac agaaagtgag gagtaaaaag atgttggaac
    42481 acaaaattga ttttatggta actcttgaag tgaaagaagc aaatgcaaat ggtgatccct
    42541 taaatggaaa catgcctcgt acagatgcca aaggatatgg tgtgatgagt gatgtctcca
    42601 ttaaacgtaa gattcgtaat cgtttgcaag atatggggaa gtctattttt gtgcaagcta
    42661 atgagcgtat tgaagatgat tttcgttcac tggaaaaacg cttttcgcaa cattttacag
    42721 ctaagacacc tgacaaagaa attgaagaaa aagcaaatgc attatggttt gatgttcgtg
    42781 cttttggaca agtttttact tatctgaaaa aatcaattgg ggtgcgtgga ccagtttcca
    42841 tcagtatggc taagtccttg gagccaattg tcatttccag ccttcaaatt acgcgtagta
    42901 ccaatggtat ggaagctaag aataatagtg gccgctcttc tgatacgatg gggacaaaac
    42961 attttgtaga ttatggtgtg tatgtactta aaggttctat caatgcttat tttgctgaaa
    43021 agactgtttt ttctcaggaa gatgctgagg ctattaaaga agttttggtt agcttgtttg
    43081 aaaatgatgc gtcgtctgca cgtccggaag gctctatgcg agtttgtgaa gtcttttggt
    43141 ttacgcattc aagcaaattg ggaaatgttt caagtgcgcg tgtctttgac ttgttagagt
    43201 ataatcaatc aatagaagaa aaaagcactt atgacgctta tcagattcat ctaaatcaag
    43261 aaaaattggc taaatatgaa gcgaaagggt taacgcttga aatcctagaa ggactctagt
    43321 atggtctatg ccgaagatga ttatttaatg ctatcaggta ttcagcattt ccaattttgt
    43381 aaacgtcaat gggcgttgat ccatattgag caacaatggc ttgataatga agcgacagcg
    43441 catggacagg ttttacatac taaagcagat aacccttaca ttaaagaaaa acgaaaagag
    43501 cttttggtct cacgtgctat gcccatttct tctgcagaac ttggactttc aggaattatg
    43561 gatgttgtgg aattttataa agatgatcaa ggtgtgtctt tgaggggaaa acgtgggaaa
    43621 tggttaccaa aagttgtgga atacaagcgc ggaaaaccta aaaaagatac cagagatatt
    43681 gtccagttgg tggctcagac catgtgttta gaagaaacgc tagactgcga cattaacgaa
    43741 ggttgtcttt attaccatag tgtcaatcaa agagtgattg ttcctatgac atcagctttg
    43801 cgtcaagaag tgaaggaatt agccgcagag atgcatgagg tttatcagag tcaaatgcta
    43861 cctaaagcag cttattttaa aaactgtcag ctttgttctt tagtcgatat ttgtaagccc
    43921 aggttgagta aaaaaacaag gagtgtgtcg cgttacatca atgaggctat gaccagtgag
    43981 gagatggacc tatgaagaag ttgctaaata ccttgtattt gacgcaagaa gatttttatg
    44041 tcactaaaga gggcgataac attgttatca agcaagaagg taaggttctc aaacggtttc
    44101 cgtttcggat tattgacggt attgtctgtt tttcttattt gggtgtgtcg cctgctttgg
    44161 tgaagttatg tacggagaat cagattaatt tatcgtttca tacaccacaa gggcgttttt
    44221 gtggtcgcta tattggttca accaatggga atgtgttgtt gcgtagagaa cattatcgtt
    44281 tatctgatcg tgaggaatct ttggaatacg caaagcggtt tattttggct aaaatttcca
    44341 attcaaggaa atacttgcta cgctttaaac gagatcatcg tcaacagatt gataccaagc
    44401 tttttgaggc tgttaatgac gaattgatat gggctttaga gatggttcag gcagcagata
    44461 ataaagactc tttaagaggg attgaaggcc aagctgctaa tcagtatttt cgcatattta
    44521 atgacctggt gttgacggac aaaaaaacgt tttacttcca aggtcggagt aaacgaccac
    44581 ccttagattg tgttaatgcc ctcttgtctt ttggttacag tttactgacc tttgaatgtc
    44641 aatctgcctt ggaagctgtc ggattagaca gttacgttgg tttctttcac acggatcgtc
    44701 ctgggcgtgc tagtttagcg cttgatttag ttgaagagtt ccgctcatat attgtagatc
    44761 gttttgtctt ttcattaatt aataaaggac aacttcagaa aaaacacttt gaggttaaag
    44821 aaaatggtag tattttattg acggaaaatg gcagagctat ttttattgat ttgtggcaga
    44881 agcgtaagca tactgaggta gaacatcctt ttacaaaaga gaaagtaaaa cttatgttat
    44941 taccctatgt acaagcgcag cttttagcta aggccatacg aggagattta gaaagctatc
    45001 caccttttat ggtttaggag atgttatatg atggttttag tcacttatga tgtaaatacg
    45061 gaaacacctg ctggtagaaa aagattgcgt catgttgcca aactctgtgt ggactatggg
    45121 caacgtgttc aaaattctgt ttttgaatgt tctgtgacac ccgcagaatt tgtggatata
    45181 aagcaccgct taacacaaat tgatgagaaa actgatagta ttcgctttta tttattgggg
    45241 aaaaattggc agaggcgtgt ggaaacactt ggtcgctcag acagctatga cccagataaa
    45301 ggtgtcttat tattgtaaaa atctcttgtg cgaagctagc tttcacagaa aaaccttgct
    45361 tgctcgcgca aaaataactt aaaaaagaag cgaaatggag ataaaaaggc ttaaaacgcc
    45421 tctatgtgtg ccatccgttt ctctataaac tgtgtcattt ggcgcagtct cacccttcat
    45481 gggtgagtgg attgaaataa ctgatctcgt ccaaaagtca aaaaagaaag gagtctcacc
    45541 cttcatgggt gagtggattg aaatttttaa atcgacatgt gcagtaccag tgtcatcttg
    45601 tctcaccctt catgggtgag tggattgaaa gatgaacctg acctcattaa aagagaggtc
    45661 gggtttttac atgcctttag tcaaccattt atctgatagc gtatcaaatt caagtttttg
    45721 catgttctag tctatggttt gcgccactag ctttcggtaa actaagggta acttaagaga
    45781 ggagttattt atgacactat cacttgtatt aatggtatcg gtttttgggg caggcttgtt
    45841 atcatttttc tctccgtgta tctttccggt ccttcctgtc tatttaggca ttttactgga
    45901 tgcagatgat tcaaagacga ttactatatt tggtaaaaaa ctctattggt atggcattgt
    45961 caaaacttta gcctttattt ttggtctatc tactattttt gtgattttag gttacggggc
    46021 tggtttttta ggaaatatcc tttatgcggt atggtttcgg tacttactgg gagccgtggt
    46081 cattatcttg gggattcatc agatgggcct cattaccatt aagagcttac aatttcaaaa
    46141 atcactgact ttccataata acaagaatcg caacggtttg ttcaatgcat ttatccttgg
    46201 tttaaccttt agctttggtt ggacgccttg tgtgggacct gttttgagtt ctgttctagc
    46261 tttggtggct tcagggggaa atggtgcctg gcaaggtggc gttttgatga ttatttatac
    46321 tcttggattg ggcattcctt tcctactcat ctcttttgcg tcaggcattg ttttgaaaca
    46381 gtttaacaag ctcaaacccc acatactttt actgaaaaaa gtaggaggcg ttctgattat
    46441 agtcatggga atcttgctta tgacaggaac cttaaataac ttagcacaac tttttggata
    46501 aaggagaaac acaatgaaaa aaggactatt agtaacaact ggtttggctt gtctcgggct
    46561 actaactgct tgctcaaccc aagacaatat ggctaaaaag gaaataactc aggacaagat
    46621 gagcatggca gctaaaaaga aagataagat gtcaacatca aaggacaagt ccatgatggc
    46681 agataaatca tctgataaga aaatgaccaa tgatggtcct atggcgcctg atttcgaact
    46741 caaaggcatc gatggtaaga cctatcgctt atcagagttc aaaggtaaaa aagtttattt
    46801 gaaattttgg gcctcttggt gttcaatctg tctatcaacc ttggcagata ccgaagacct
    46861 ggctaaaatg tcagataaag actatgtggt cctaacagtt gtctcgccag gtcatcaagg
    46921 ggaaaaatca gaagcagact ttaaaaaatg gttccaagga acagactata aggacttacc
    46981 agtcttgtta gatccggatg gcaagctatt ggaagcttac ggcgtcagat cttacccaac
    47041 agaagttttc attggaagtg atggtgttct tgctaaaaaa cacattggtt atgccaaaaa
    47101 atcagacatc aaaaagaccc ttaaaggtat acattaggaa ggaccagctg ataggcatta
    47161 gaaaaaagga gttgagttta tggaacacaa atggaaatta tggctattta tcgttggagt
    47221 ggtcttgtta ataggcggag cttctgttct cattcagaaa ggtcaagcca aggcttttag
    47281 tcaaggcaag cctcaactac cagccaaaaa agtcaaatcc actaaagtag atcccaatgc
    47341 ccctgttgat caaaaaatga tttacctagc tggtggctgt ttctggggcg ttgaagaata
    47401 tttttcacaa gtggatggcg tcttagatgc ggtgtcagga tatgccaatg gtagaggcga
    47461 taccactaat taccagttaa ttcatcagac tggtcatgca gaaaccgttg aagtggccta
    47521 tgatgcgaac cgtattagct tgaaagaatt attactgcat tttttccgaa ttattgaccc
    47581 aaccagtctt aataagcaag gaaatgatcg cggtagtcaa taccgaactg ggatttacta
    47641 tactgacaaa gcagaattag ctattattga tgaggtcttc aaagaaaaag ctaaggatta
    47701 caagaaaaaa atagtggttg aaaaagcacc attgaaacac tttattaagg cagaagacta
    47761 ccaccaagat tacctcaaga aaaatccaaa tggctactgc catattgaca tcaaccaagc
    47821 gacttatcct gtgattgatg aaagcaagta cccaaaacca agtgccactg agatcaaagc
    47881 aaaactatct gcagacgaat accgagtgac gcaaaaaaac gaaactgaaa aagctttttc
    47941 taatcgctac tgggattctt ttgatgcagg aatttacgta gacgttgtga caggagaacc
    48001 gcttttctct tcaaaagaca aatttgaatc aggttgtggt tggccaagct ttagccgccc
    48061 catcagccca gatgttgtcc gctacaagga agataagagt ttcaatatga cgagaacaga
    48121 agtgcgcagc cgttctggca attctcatct agggcatgtc tttactgacg gacctaaaga
    48181 ccaaggcggc cttcgttact gcatcaatag cttgtctatt acctttattc caaaagctga
    48241 tatggaagct aagggctatg gttatttatt atcatctgta gaatagggtt aggcctaaaa
    48301 atctgatata atagaagaaa gactagtatg agagggccat gcaaggccct ttataaagat
    48361 aaggagacac cgtgtgtact cattgttaat tgtagaagac gaataccttg tgcgccaggg
    48421 tattcgttct ttggttgatt ttagccagtt caagattgat cgggtcaacg aagcagaaaa
    48481 tggccagttg gcttgggact tgtttcagaa agagccttat gatattgttt tgacggatat
    48541 caatatgccc aaattaaatg ggattcaact ggcggagttg attaaagagc atgcgcctca
    48601 gacccatttg gtttttttaa ccggttatga tgactttaac tatgctttgt ctgctttgaa
    48661 gttaggggca gatgattact tgctcaaacc cttttccaag gccgatgtgg aagatatgtt
    48721 aggaaagctc cggaaaaaat tagaactttc caagaaaaca gaaaccatcc agaaattggt
    48781 tgagcagcct caaaaagaag tatcagcaat agcaatggct attcatgagc ggttggcaga
    48841 ttctgatttg accctaaaaa gcttggctca gcagtttggt tttagcccta attaccttag
    48901 cgtcttgatt aaaaaagagt tagggatgcc ctttcaagat tatctggtac aagaacggtt
    48961 gaaaaaagcc aagcttctct tgttaaccag taatcttaaa atctatgaaa ttgcagagca
    49021 ggtcggtttt gaggatatga attatttttc tcagcgcttt aagcaactgg taggcgttac
    49081 cccaagtcag tataaaaaag gaggccaggc atgaagcgtt atcccctact ggtccagttg
    49141 atttcttatg tctttgtgat cgtaattgcc ctcattacca tgcttggttt gctttattac
    49201 cagacgagtt ctcgtaatat caggcaatta attgaacgtg atacccggca gagcattcgg
    49261 caaagttccc aatttattga cgcttacatc aagcctctta aagaaacaac ttcggtgctg
    49321 gcgaaaaata cggaaattca agcctttgct agtcaaattc atcaagaaaa tgacaaacag
    49381 gttcttcagc tcatgaagat ggttcttgcg accaattccg atttacaagc agctgttctg
    49441 gtgactaagg atggtcgaac ggtgtctacc aattctcagt tgaccatgaa aacctccagt
    49501 gatatgatgg cagaaccctg gtataaagca gccatagacc gtcagtccat gccaatcttg
    49561 accccagctc ggcaattatc cctttcttct aaaaaagaat gggtagtttc tgtgacccaa
    49621 gaggtagtgg atgctgctgg tcataattta ggcgtgctaa gacttgatat tgcatatccg
    49681 actattaaag cgtctttaga tcagcttcag ctaggccgcc aaggctttgc ctttattgtg
    49741 aatgataagc atgaatttgt ttaccatccc aaaaagagtg tttacagttc ttctaaggag
    49801 atggctgcga tgaagcctta tttagcgatt cagaatggtt acactaagga caagacatct
    49861 tttgtttacc aaaaactcat tcctaacagt caatggactt tagtgggagt ggcgtcactg
    49921 gatcagttgc accgggtgca gcgccaaatt ttttggtcct ttcttggaac agggcttcta
    49981 gcctgtctga tttgtggctt tgcaactgtc ttagccttac gcagatggat tcgtcccatt
    50041 caacaattgc agcaagttat tcttgctatt caaaaaggag atcgtcagtt acgtgcccaa
    50101 gaaacgggtt ctccagaatt gacagacctt gcccaacagt ttaatgcgct cttagatcaa
    50161 attgatagct tgatggttgc cgttgcggat aaggaaaagg cgattgggca gtataggtta
    50221 caagccttgg ctagtcagat taacccgcat tttctctata acaccttgga cactattatt
    50281 tggatggcag aatttaatga cagcaagcgc gtggtagcag tgaccaagtc tctagctaag
    50341 tattttcgtt tggcccttaa tcaggggaac gaatacattc gtttggcaga tgaactggat
    50401 cacgttagcc aatacctttt tattcaaaaa cagcgctatg gagacaagct aagttatgaa
    50461 gtgcaaggct tagatgtcta cgcagacttt gttattccta agcttatctt acagccctta
    50521 gtagaaaatg ctatctacca tggcatcaaa gaagtcgatc gcaaaggcat gatcaaggtt
    50581 acggtatctg atacagctca gcatctggtg ttgactgttt gggataatgg taaaggcatt
    50641 gaagactctt cactgaccaa tagtcagagc ttgttgacta ggggaggtgt gggccttaaa
    50701 aatgttgacc agcggttaaa acttcactat ggtgaaggct accacatgac cattcatagc
    50761 cagtcagacc agttcactga aatacaatta agccttccta aaatgcatga gttaatggca
    50821 gacaacacac aggaaaacga gtaagattac aggaagtgca tgtcagcctt ttccctaagt
    50881 tagggtattg gaaacaggaa ccttagaaag gacatcatga gtttagcaac tgactatttt
    50941 agccgacaga cccccatagt tgaaaagtta atagcttacg ggtttgagaa acgagacaat
    51001 ggttacttct ataacgaaca gtttatggaa gaggaatttg aggcgcaact tagaattgat
    51061 gaggctggta atatctggga cagggttatt gattgtgact tggaggagga ttatttgcct
    51121 ttacaacagg cagcctgcca aggaacctat agtgggcagg tcagagcggc ctatttggaa
    51181 cttttggagc gtttatcagt agcctgtttt gaagccactc cttttcagtc aatgcaagct
    51241 aatagacttg ctaagcatat caccaaagaa tggtctgacc caatggacta tccttttgag
    51301 aagcacccag accttgcaac ttatcgggta gggggaaaat ggtatgccat gattttttct
    51361 ctcttggctg ataaattgga ccagatacca gagagattag taggacagat atgtgaagtg
    51421 atgactgtca aagttaatcc caagaattta cctcagttac tgcagcaaga gggcatttac
    51481 cctgcctacc atatgtcaaa aaacaattgg gttagtgttg tcttggatga taaagtaaca
    51541 gatgataagc tttggacgtt agtcactcaa agtcgtcaac tagtcaaccc caagggtctt
    51601 tctaatccta atggtcctga ttattgggtc attccagcta atttgaaata ctatgatatt
    51661 gatgcagaat ttgcagccaa tgatgtgatt ttatggactc aaaaagctgg tattgccgtg
    51721 ggagactacg tgctgattta tatgacagcc ccagtcaaat ccattcgcta tacctgccaa
    51781 gttctagaaa ccaatatatc taaccaaggc tatcgtaaaa attctaacat tgacaaactc
    51841 atgcgtctcc gaaaatgcca acagtacgag gatggtctct tgtcctttga ccttatgaaa
    51901 gaacatggtg tagctgccgt gagagggcca agacgattaa gccctcaatt aattgctttt
    51961 tttaagaaaa aagagtatct taaaggaaac aactaagggc actaaaggag aataagagat
    52021 ggttcaattt gtagcagatc aaagtttttg ggaacttttt ccagatgcca aactaggtgt
    52081 cgtcttatta aaggatgttc agaatcaagg ggagtcacca gaagatgtca aacagctatt
    52141 agcagacagc catgagttgg caaaagctta tttaacagca gacaatttta gtgataatca
    52201 ggtagttcaa gtctaccgca aggcctatca acactttaaa accaaaaaag gagctcgctc
    52261 tagcattgaa gcccttctca agcgggtgtc aaatggtcaa agcattccgt ctattaaccc
    52321 actagtggat atttataatg cggctagtct acgttttggt ttacctgttg gagccgaaga
    52381 tagtgacagt tttatcggag atttgcgtct gacgataaca gatggtggtg acgactttta
    52441 cttgattggg gatgctgata acaacccaac cttgccaaat gagctgtgtt ataaagatga
    52501 tattggagcg gtttgtcgtt gccttaactg gcgagatggc gaacgcacca tggtgataga
    52561 acacacccaa aatgcatttc tgattatcga agctcttgat caagaaggtc aaaatagatt
    52621 gcaagaagct ctgaaattca ttgaaggcag cgcaaaaatg taccttcatg caatcacttc
    52681 tgtgcatgtg ttggataaag acaatccaca cgtgccactt tttacagaaa actagattag
    52741 taggatgagc tgtgcaaaat agaaggttaa caaaaaagcg agtaaacgaa tatcctgtca
    52801 tttaggtttt cgtttactcg ctttttgatg agattttact gctgtcctag caaaaggtga
    52861 ggatgaggtc gtatatcaca tagaggtttt ctgttaagcc ttatttgtta ctaaagaaga
    52921 atggtggtgt gtaatgacta agggtctcgt aacaagcctt ggcttgctca ttgtcttcac
    52981 agacaatcaa gcaagtatca tcaccacaga ccgttgctac aatttctgga atttgcatgg
    53041 catctaaaat ggagccaaag gattgggcta gtccaggtaa cgtttttaaa ataatttgat
    53101 gttgaactat ctttaacatg accaaagcgt cttccatgta aaaacgaaga cgatgttccc
    53161 agcgggtttg tgaaatggct aacgcttcat agtgtgtgtc gtttccagaa gttactttga
    53221 ccaggttcaa ttccttcatg tcacgtgata gggtagcctg agtgatcgtg atgccatttt
    53281 tttgcaaccg ttcttgtaat tcttgctgtg tatgtatagt tgtctcagag atgagggaac
    53341 gtatgagttg gtgacgcgtc tctttcttat tcattgttat aatcttcctt taacgtaatt
    53401 gataacaatc cgagtatagc aaaaagagga gaaggtgtaa agtttttgat gaaccgctta
    53461 caaaatggct tttttatggt aaaataaaga tgatgtttag aaaaaggaga tttgtgtgat
    53521 tcgaagagaa gattatcaat accttagaaa actaaacgat tttcgctact tttctattga
    53581 acaatttgac aaaattgtag ggcagatgga attccgaaaa gctaaaaagg accatatcct
    53641 tttttttgag ggagataaaa gagataagct ttttctagtg acctctggtt atttcaaggt
    53701 ggagcagtcc gatcaatcag gaaccttcat gtatacggat ttcatcagac acggtaccat
    53761 ttttccttac ggtggccttt ttacagatga ttattaccat ttttcagtgg tagccatgac
    53821 agacgtgact tatttttact ttccagtcga tttatttgaa gattattcgc ttgaaaatcg
    53881 tctacaaatg aaacacttat atagtaagat gtctaagctg ctcgagttac atgagttgag
    53941 ggtccgaaac ttgattacat caagtgctag ttctcgtgtg attcaatctc tggcgatttt
    54001 gctggttgaa atgggtaaag acagtgatac cttacctttt caattaacaa caacagatat
    54061 tgctcaaata agtgggacga caagagaaac agttagccat gtgcttagag atttgaagaa
    54121 gcaagaattg attaccataa aaggtaagta tttgacttat ctagataaag actatttttt
    54181 acaatacaca aagtgaatta aaggtcagaa cactttattt taaaagtttt tctgacttat
    54241 tttaatttat aagtataaat ttttacacta agatgtaaaa aacatacaag taaacgaata
    54301 caaatctata aaaataaaaa caacgctcaa aaaatgtaag cgattactca aaatagctgt
    54361 gagaaatacc ctatttttat cttttttaag gagtacacta ggaatataag caagagttaa
    54421 gaatcttgac ggtgaattca caaaaaccaa ttagaaagag gtaattctta tgactgctca
    54481 aacaccaatt catgtttatt ctgaaattgg aaaattaaaa aaagtgttgc tccacagacc
    54541 cggtaaagaa attgaaaatc ttatgccaga ctacttggaa cgcttgttgt ttgatgatat
    54601 tccattctta gaggatgccc aaaaagaaca tgatgctttt gcccaagctt tgcgtgacga
    54661 aggtattgaa gtcttgtacc ttgagacctt agctgcagaa tctcttgtca ctccagaaat
    54721 tcgcgaagct ttcatcgatg aatacctaag tgaagctaat atccgtggaa gagctactaa
    54781 aaaagccatt cgtgaattgt tgatggctat cgaagacaat caagaattga ttgaaaaaac
    54841 catggcaggg gttcaaaaat ctgaacttcc agagatccca gcatctgaaa aaggcttgac
    54901 tgacttggtt gaatccagtt acccatttgc catcgaccca atgccaaacc tttatttcac
    54961 acgggaccca ttcgcaacta tcggtacagg tgtttctctt aaccacatgt tctcagaaac
    55021 ccgtaaccgt gaaacccttt atggtaaata cattttcact catcacccaa tttatggtgg
    55081 tggcaaagtg cctatggttt atgaccgtaa tgaaaccact cgcattgaag gtggggacga
    55141 acttgttctt tcaaaagatg tgcttgcggt tggtatttct caacgtacag atgctgcttc
    55201 tattgaaaaa ttgttggtta acatctttaa acaaaacctt ggcttcaaga aagtattggc
    55261 ctttgaattt gcaaataacc gtaaatttat gcacttagac actgtcttta ccatggttga
    55321 ctatgacaaa tttaccattc acccagaaat tgaaggcgac cttcgtgttt actctgtcac
    55381 ttacgacaat gaagaacttc atatcgttga agaaaaaggt gatttagcag aacttcttgc
    55441 tgctaacctt ggtgttgaaa aagttgacct tatccgttgt ggtggtgaca acttagtagc
    55501 agcaggtcgt gaacaatgga acgatggttc taacaccctt actatcgcac caggtgtggt
    55561 tgtggtttat aaccgtaata ccattaccaa tgccattctt gaatctaaag gcttgaaatt
    55621 gatcaagatt cacggaagtg aattggttcg cggtcgtggt ggacctcgtt gtatgtcaat
    55681 gccatttgaa cgtgaagata tttaataagc tatggtaaag gtggttatag gtcagaagcc
    55741 ttttcaacag gacaattttt agctgaaacg aaaacagaag cacgattaac acgaattgca
    55801 accttagcag actatcgtgg gcagggttat ggtgctaaag tcattgaagc gctcgaaact
    55861 tatgccagac aggaaggctt tcgccaacta accattcaca gtgaactgac agcacaaacc
    55921 ttttatgaaa acctaggtta tcagacctat ggtcccaagt gtttagaaga tggtgagtat
    55981 tgtcagtccc ttgcaaaaac cattcttaaa tgggagaaga atatggacat agcaatgcta
    56041 attgcgattg ttggtggtct attaggctgc tatctctatc tcacaaaaaa taattaatca
    56101 aaacagatta cagttaacac tcgaaggaga caatagatga cacaagtatt tcaaggacgt
    56161 agctttctag cagaaaaaga ttttacacgc gctgaattag aataccttat tgatttttca
    56221 gcacatttga aagatttgaa aaaacgtggt gtgcctcatc actacttaga aggtaaaaac
    56281 attgccctct tgtttgaaaa aacatcaact cgtacgcgtg cagcttttac aacagcagcc
    56341 attgacctag gtgctcaccc agaatacctc ggtgccaatg acatccaact tggtaaaaaa
    56401 gaatcaacag aagacactgc caaagtattg ggtcgtatgt ttgatgggat tgaattccgt
    56461 ggtttcagcc aacgcatggt tgaagaattg gcagaattct caggtgtgcc agtttggaat
    56521 ggtttgactg atgaatggca cccaacccaa atgcttgctg actatttaac agtgaaagaa
    56581 aactttggca aacttgaagg ccttaccctt gtttactgtg gtgatgggcg taataacgtt
    56641 gccaattccc ttcttgtgac tggtgctatc cttggtgtta acgttcatat cttctcacca
    56701 aaagaactct tcccagaaga tgacattgtg acattggctg aaggctatgc taaagaaagt
    56761 ggcgctcgta tccttatcac agaagatgct gacgaagctg ttaaaggcgc agacgtcctt
    56821 tacacagacg tttgggtatc aatgggtgaa gaagacaaat tcaaagaacg tgttgaattg
    56881 cttcaaccat atcaagtcaa catggacctt gttcaaaaag caggaaatga caagcttatc
    56941 ttcttgcact gcttgccagc tttccatgac acaaataccg tttatggtaa agacgttgct
    57001 gaaaaattcg gcgtgaaaga aatggaagtc actgatgaag tcttccgcag caaatacgct
    57061 cgtcattttg atcaagctga aaaccgtatg cacactatca aagcggttat ggcagcaacc
    57121 cttggtaacc tctttattcc aaaagtgtaa taaggactgg tactccttaa ctcatttcac
    57181 atatcaatgt gatcccttta atttaacaat ttaactactt aaaaacgtac tttaactaca
    57241 tgacaagtcg ttctggttct cgcgtccttg accggaacta gaacggctta tttttatgaa
    57301 aaggtaagag gtaatcatta tgacagaaga aaaaaaacgg ggttttagaa ttccttcttc
    57361 ttacaccgtt ctttttatca ttatagccat catggcagtg ttaacttggt ttattccagc
    57421 tggcgcctac gaaaccgcta agggcggtgg tgttatttca ggaacctaca aaacagtagc
    57481 atccaatcct caaggattgt ttgacatctt gatggctccc gttcgaggca tgttaggtgt
    57541 tgaaggcact gatggtgcta ttcaagtgtc tttctttatc ttaatggttg ggggcttttt
    57601 aggagttgtc aacaaaacag gtgctcttga cacaggaatt gcgtcagtgg ttcgtaaaaa
    57661 caaaggtaga gaaaaaatgc tgattgctat tttaatccct ttgtttgctc taggtggaac
    57721 gacctatggt atgggggaag aaaccatggc cttttaccca cttttaattc ctgttatgat
    57781 tgcggttggt tttgacagta ttgttgctgt agccattatt ttgattggtt ctcaaattgg
    57841 atgtctagcc tccactatta acccatttgc aactggtgta gcagctgatg ctgctggtgt
    57901 cagcattgca gatggaatga tttggcgtgt tatccaatgg gttattcttg tcggcatgtc
    57961 tatttggttt gtttacaatt acgctagtaa gattgaagaa gacccaagta aatcattggt
    58021 tgcagacaag gaagaagagc ataaggaact cttccagttg caaaattctg gagaagactt
    58081 aaacaagcgc caacgaaacg ttttgaccat ttttactttg acctttgtca ttatgattct
    58141 tagtttgatt ccgtgggaag attttggcat caaattcttt actaatatca atacttggtt
    58201 aaccacaatg cctatcttag ggggagttat tgggaaaacc atgggagcat ttggtacttg
    58261 gtatttccca gaaatcacca tgctctttat catgatgggt gtcttagttg ctattgttta
    58321 tcgtatgagt gaagaagact tttttagctc ttttttgact ggtgcaggtg aatttttagg
    58381 tgttgccatg atctgtgcta ttgcacgcgg tattcaagtt atcatgaatg gtggtatgat
    58441 tacagccact atcttacact taggtgaaac aagtctttct ggtttatctt ctcaagtttt
    58501 tgtgatatta gcttatattt tctacctccc aatgtccttc ttgattccat caacatcagg
    58561 acttgctggg gctacaatgg gaattatggc accgcttgga caattctcaa atgtccctgc
    58621 tcaccttgtt attacagcct tccagtcagc ttctggaatc ttaaacatga tttctccaac
    58681 ttcagcaatc gttatgggag cacttgcgct tggtcgcgtt gaccttggta cttggtggaa
    58741 attcattggt aaatttattg taatggtgat gcttgtaagc gtgctattac ttgtagttgc
    58801 aacattcttt taacagatag gaggttccta tggaatccta tatcacacct aaacatcaag
    58861 aggcttgtgt agctgccatt aaacagatcg tttcttaccc ttctgtttgt catgaaggag
    58921 aaaatggcac accttttgga caggccattc aagatgttct cgaagcaacc ttagacttat
    58981 gtcaaggtct tggcttccat acttatattg atcctaaagg ttactatggt tatgctgagt
    59041 taggtgacca aaaagaggtc ttggctattc tttgccattt ggacgttgtt ccagaaggag
    59101 atcgtcagtt atggaagaca gatccttttg actgtgttga ggcagacggc tgtttatttg
    59161 gtcgaggcac tcaagacgat aaagggccta ctatgatggc gctatttgcc accaaagcct
    59221 tgatagatgc aggcgttacc tttaataaac gcattcgttt tatttttgga acagatgaag
    59281 aaactttgtg gcggtgtatg aatcgctaca atgatgtaga agaacaggct acctttgggt
    59341 ttgctcctga ttcaagtttc cctttaacct atgccgaaaa aggcctactt caggcaaaat
    59401 tagtggggaa aggttctgat aaactgtcac ttgaaatcgg acaagcctac aatgttgttc
    59461 ctgcaagagc ctcttatcaa ggtgataagc ttgaggcttt acaaaaagaa ctagataagc
    59521 ttggctttga gtacgtcgtc aaagagggag aattaacggt ttatggtctc gcccaacatg
    59581 ctaaagatgc tcccgatggc atcaacgcta tgattaggct tgccaaagct ttagtggtcc
    59641 ttgaacctaa caaaaccctt gattttcttg ctaatgtcat tgatgaagat ggcagagcac
    59701 ttaatatttt tggcagaatc gaagatgaac cttcaggcaa attaagcttt aatgccgcag
    59761 ggcttacctt aaccaaagac aaggcagaaa ttcgcctaga tattcggatt ccagttttgg
    59821 cagataagga aaaattagtc caacaattaa gccaaaaagc acaagaatac ggcctaacct
    59881 atgaagaatt tgattatttg gccccattat atgtgccatt agacagtgaa ttggtaacaa
    59941 ccttgttatc tgtctatcgg aaaaaaacag gtgatcaaag ccctgcccaa tcatcaggag
    60001 gggcaacctt tgctagaaca atgaagaatt gtgttgcctt tggtgccctt ttccctgatg
    60061 ctgctcaaac ggaacaccaa gaaaatgaac atattgtttt agcggaagct taccgcgcta
    60121 tggatattta tgcggaagct atttaccgac taacgcgata acaaaatatg aggagtaatt
    60181 atgacgaaac aaaaaatcgt agtcgcactt ggaggaaatg ctattctttc aacagatgcg
    60241 tcagcaaaag cacaacaaga agccttgatt tccacatcaa aatcattggt taaattaatt
    60301 aaagaaggtc atgaagtcat cgtgacccac ggcaatggcc cacaagttgg taatctctta
    60361 ttacaacaag cagcggcaga ttctgaaaag aatccggcta tgcctttgga tacttgtgtt
    60421 gccatgacag aaggtagcat cggtttttgg ttagttaatg cctttgataa tgaattgcaa
    60481 gcccaaggta ttcaaaaaga agtggcagct gttgtcactc aagtgatcgt ggatgccaaa
    60541 gacccagctt ttgaaaaccc aacaaaacca attggtccat ttcttaccga agaagatgcc
    60601 aaaaaacaaa tggcggagtc tggtgcaagt ttcaaagaag atgcaggtcg tggctggcgt
    60661 aaggttgtgc catcaccaaa accagttggt attaaagaag ccaatgtcat cagaagtctc
    60721 gttgattctg gcgttgttgt ggttagtgct ggtggtggcg gtgtgcctgt tgtggaagat
    60781 gctactagca agtccctgac tggtgtggaa gctgttattg acaaggactt tgctagccaa
    60841 accctttcag aattggtgga tgcagacctc tttatcgttt tgacaggagt tgacaatgtt
    60901 tacatcaact tcaacaaacc tgaccaagcc aaattggaag aagtgactgt ctctcaaatg
    60961 aaagaataca tcacacaaga ccaatttgca ccaggtagta tgttaccaaa agtggaagct
    61021 gccattgctt ttgttgaaaa caaaccaaat gctaaagcca ttatcacatc gctagacaat
    61081 attgacaatg tactatcagc aaacgctgga acacaaatta tcgcagggta atcaagagga
    61141 tttttagttc tgtttaaaag actcatttaa tggtattttc tgaagagtac gactgacata
    61201 aagagttgat actgttttta aaggaaaaga gtgtgccata ataaaaaaca atagtagtat
    61261 tagaaaaggc taattttatt gagaattagc cttttctttt agctttgata ggtgtataat
    61321 aactatacta ttttttattt ttcaaaatat tagaataaac aaaagtggac aacgtataaa
    61381 gagaactgct aagtcgttga gttcattagt cccaaaaaga ttaccaaaaa tgaaggagga
    61441 gctatgaaga aaagttttat tcatcaacaa gaggagattt cctttgttaa gaatacgttc
    61501 actcagtatt tgattgctaa gttagatgtt gttgaagtgc aaggacccat tttaagtcgg
    61561 gtcggggatg gtatgcaaga taatttgtcc ggtactgaaa atccagtatc tgtcaatgtc
    61621 ttgaaaattc ctaatgcaac ctttgaagtt gtgcattcat tagcaaaatg gaaacgtcac
    61681 accttagccc gttttgggtt taatgaaggt gaaggtcttg ttgttaatat gaaggctctc
    61741 cgacctgatg aggattcact tgaccaaacc cattctgtct atgttgacca atgggactgg
    61801 gaaaaagtca tccctgatgg caaacgtaat ctcgcttacc ttaaagaaac cgttgaaacc
    61861 atttacaagg tcattcggct aactgaatta gctgtagaag ctcgttatga tattgaggct
    61921 gttttaccta agaaaataac cttcattcat accgaagaat tggtagctaa ataccctgat
    61981 ttgacaccca aagaacgtga aaatgccatt actaaagaat ttggagcagt ctttttaatt
    62041 ggtattggcg gggttttacc tgacggtaaa ccacacgatg gccgcgctcc tgactatgat
    62101 gactggacaa cagaaactga aaatggctat aatgggctta atggtgatat tttggttcgg
    62161 aatgaccaac ttggttcagc ctttgaatta tcctcaatgg ggatccgtgt ggatgaagag
    62221 gccctaaaac gtcaggtgga aatgactggt gaccaagacc gcttagcctt tgattggcac
    62281 aaatctttgt tgaatggact tttccctcta acgattggtg gaggaatcgg tcaatcacgt
    62341 atggtcatgt ttttgttgcg taaacaacat attggagaag ttcagacctc cgtttggccc
    62401 caagaagttc gtgatagcta cgataatatt ttataagtaa tcacatcatt ttgctaagtt
    62461 ttccacttgt ataagagact ttaaataaat gatcagaaat attgaaaaaa gaaatcattt
    62521 ttaaggttta gagctagaaa tttgctataa taaatgttat gagagttgta tcaggtgaat
    62581 ttggtgggcg tcctttaaag acgctcgatg gaaagataac acgccctact tcagacaaag
    62641 ttagaggtgc gatttttaat atgataggac cttactttaa tggtggtcgt gttttagatt
    62701 tgtttgcagg ttcaggtgga ttagccattg aggctgtttc tcgtgggatg tctgctgcag
    62761 ttttggttga gaagaatcgt aaagcgcaag ctattattca agacaatatt ataatgacta
    62821 aagctgagaa tcggtttacc ttgttaaaaa tggaagctga gcgagctatt gattgcttga
    62881 ctggtcgatt tgacttagtc tttttagacc ctccttatgc caaagaaaca attgtggcaa
    62941 ctattgaagc tttagcagct aaaaacttat tgagtgaaca ggttatggtt gtctgtgaga
    63001 cagataaaac agtcttgttg ccaaaagaga ttgcaacgtt aggtatttgg aaagaaaaaa
    63061 tttatggaat tagtaaggta acagtttatg ttaactaaag taggacttta tacagggtca
    63121 tttgatcctg ttacaaacgg tcatctcgat attgttaaac gggcaagtgg cctatttgat
    63181 caaatatatg ttgggatttt tgataatcct accaaaaaaa gctattttaa actagaagtt
    63241 cgtaaagcaa tgcttactca agctctggct gattttacaa atgtaattgt agtaacttcg
    63301 cacgaacgtt tagctattga tgtagctaaa gaattacgag taactcactt gattagaggc
    63361 ttgcgaaatg caactgactt tgagtatgaa gaaaatttgg aatattttaa tcacctttta
    63421 gctccaaata ttgaaaccgt ctatttgata tcaagaaata aatggcaggc ccttagctct
    63481 agtcgtgtga gagagctaat tcattttcag tcttccttag aaggtttggt tcctcagtcg
    63541 gttattgctc aagtggagaa aatgaatgaa aagacttaaa aaaatcaaat ggtggttagt
    63601 gggtctgcta gctttaatct ctttgttgct agcgttattt tttccgctac cttattatat
    63661 tgaaatgcct ggaggcgctt acgatattcg gactgtctta caagtcaatg gcaaagaaga
    63721 caaacgaaaa ggagcttacc agtttgttgc agtgggcatt agtcgtgcca gcctcgctca
    63781 gctattatat gcttggctga caccgtttac tgaaattagt acagcagaag atacaacagg
    63841 cggatacagc gatgctgatt tccttcgaat taatcaattt tacatggaaa catcacaaaa
    63901 tgcagctatt tatcaagctt tatccttagc tggaaaacca gttacattag attataaagg
    63961 cgtatatgtt ttagacgtaa acaacgaatc tacttttaaa ggaacgctac acttagcaga
    64021 tactgtaaca ggtgtaaatg gtaaacagtt tactagttca gcagaactta ttgactatgt
    64081 ttctcaccta aaactagggg atgaagttac ggttcagttt acgagtgata ataagcctaa
    64141 aaaaggagtt ggccgtatta tcaaactgaa aaatgggaaa aatgggattg gcattgcctt
    64201 gactgatcat acaagtgtca attcagaaga cacagtgatc tttagtacta aaggagtagg
    64261 aggacctagt gctggtctaa tgtttactct tgatatatat gatcaaataa ctaaagaaga
    64321 tttacgcaag ggccgtacaa ttgcaggtac aggaactatt ggcaaggatg gcgaagtagg
    64381 agatattggt ggtgcaggtc ttaaagtagt tgcagcagct gaagctggtg cagatatatt
    64441 ttttgttccg aataatcctg ttgataagga aattaaaaaa gttaatccaa atgctataag
    64501 taattacgaa gaagccaaac gggcagccaa acgactaaag accaaaatga agattgttcc
    64561 tgttacgact gttcaagagg cactggttta tcttcgcaaa taaaataact atgaatgtat
    64621 tatattcaat tatattcacg ctattaactc ataaaaaacg gttgaaccag atagacagat
    64681 ccttgaccag tcttttgggt tcaatcattt tttacataaa acatatctaa cttgacagcg
    64741 taaaaaagat tttataaaag tctagtggta aaaaggcaat agagaattga gtaaacttta
    64801 gtcgattatc tggaaataga gcatactaaa aatacctagt gaaaattgat ttttttcact
    64861 agctcatcca agaacttgcg cagataatca tgagtccatt ccatgtctct attattcaaa
    64921 gccttgcaat agacaagtta acgttataac aactaaatta aaaacttgag attgaaaaat
    64981 ccccataaac ttattttaca aggaggtaag gctatggtaa ccattaaaca agttgctgaa
    65041 gaagcaggtg tttctagatc aacagtctcc aggtatattt ctcaaaaagg atatgtatct
    65101 gatgatgcaa ggcataaaat caaagcagcg atagcaaaat tacattacac tccaaatgtc
    65161 ttggcgcagt cattgaagac gaaaaaaaat caactagtcg gtttattatt accagacatt
    65221 tccaatcctt tttttccgag gttagcaagg ggagcagaag aatatttaaa agaaaagggg
    65281 tatcgggtta tgctaggaaa tatttcagac agcgaagctc ttgaagaaga atacgtccat
    65341 gtccttcttc aaagcaatgc tgctggcatt attactaccc atgactttac aaagcggtat
    65401 cctactcttg ctattccagt tgtagtggta gatcgtgttg accaagagac ccagtacggt
    65461 gtcttttcag ataatagggc agggggctta ttggcggctc agactgtctg gcaagcaggg
    65521 gcgaaagaag ttctgttaat aagaggtccg ctggataatg ctgaaaacat taatgagcgg
    65581 tttgaagcta gtttttctta ccttcaaaaa caagacgtga ctatgtatgt gtgtgatagt
    65641 cagaattttg attttgaaag tattcagcta gaagctagtt acaacctcaa gtgttaccca
    65701 acaatagata gtattatagc accttctgat atccatgcta ttgcttatat tcatgaactg
    65761 cattctcaag gtaaaaagat tcctcaagat gttcaaataa taggttatga tgacatttta
    65821 atgagtcaat ttatttatcc ttctttatcg actattcatc aatcctctta tttgatgggc
    65881 cgttatgccg ccgaattagt ttatactatt gctagtcaat taactgtgaa agcaaatcgg
    65941 attaaattgc ctgttcacta cgttgagcga gaaacaataa ggaaaagata agtaataata
    66001 ttagtccaga ttttagcagg tatgatgaag atttattggg atttaccttc tactttaaaa
    66061 gatgttatct gtcattactt tcatcgctat cagtcaaaac gcattcttat gcaactctta
    66121 accttaatct taatgtcttt ttgataacat agaggaatgt tacacgatga tgacgcaata
    66181 aagcctaaat atagtaattg tcgtgatttt atagctagtg agtaatgaga tagcaagtct
    66241 ctcatttact tacaaaagtc aaaaaatagt gtataatggt tgagttacaa ataacactgc
    66301 aaaaaagata acaagtgtcc ataattatct aagactataa aggcgatata gacagatata
    66361 aaaaagatga cgaatcagtt atcactggac aattaaccga tttagttaca actaatggat
    66421 ttttcagaaa ggtgtcaaat gaaaaaagaa atttcgccag aaatgtacaa ctataataaa
    66481 tttccaggtc ccaaatttat tcattttgaa gagcaagtta aggctgaagg cattgatttg
    66541 ttactcttag aagatgttaa gaacgctttt gatacgacta gctttggtca acgttataca
    66601 gaagttctcc taaagtatga ctatattgtt ggcgattggg gaaatgaaca gcttcgtctt
    66661 aaagggtttt ataaggatag tgatgatatc aagaaaacga atcgcatctc acgtttagaa
    66721 gattatatta aagaattttg caattttggt tgtgcttatt ttgttttaga aaatcttcat
    66781 ccacaagata ttaaatttga agaggagcgc caaccaagac gaaagaaatc acctaaatca
    66841 aaatcaaatc gtcgcaagcc aaactattca aatcagcagc ccgcaacacc taagagtaaa
    66901 tcgaagcgga tatcaaaaga aaagcaacct gaaaaccaag cgtttaccag tcaaaaacgt
    66961 cgaagtaata ctaagcataa agaaaagtca aaacgtaatc agactagtca acttaatacc
    67021 aaaattagtc attttatcat cagaaagaaa gataaataat ccatgaaacc atcgatttat
    67081 agcttaacac gcgatgaact gatcgcgtgg gcagttgaac gcggccaaaa acagtttaga
    67141 gctactcaaa tttgggattg gctttataaa aaaagagttc aatcttttga ggagatgacg
    67201 aatatttcta aagattttgt ttctatttta aatgatagtt tctgtgtcaa tcctttaaaa
    67261 cagcgagttg tacaagagtc agctgatggt acagtaaaat atttatttga actgcccgat
    67321 ggtatgttaa ttgaaacagt tttaatgcgt caacattatg gtcattctgt ttgtgtgacg
    67381 actcaagttg gctgtaacat tggctgtact ttttgtgcta gtggattgat caaaaagcaa
    67441 cgtgatctaa acagtgggga aattacagct caaatcatgt tagtccaaaa atattttgac
    67501 gatagaaagc aaggtgagcg ggttagccat gttgtcgtaa tgggcattgg tgaacctttt
    67561 gataattaca aaaatgtcat gtgctttctt cgcgtcatca acgatgataa tggcttagca
    67621 attggtgccc gtcatattac agtctctacc tcagggttag ctcacaagat tcgggatttt
    67681 gcaaacgcgg gagtacaggt taatttagca gtctcgttgc atgcaccaaa taatgattta
    67741 cgttcaagta ttatgcgagt aaatcgctct tttccgcttg aaaagctctt ttcagctata
    67801 gaatactata ttgaaaaaac gaatcgtcgt gtcacttttg aatacattat gctaaatgaa
    67861 gttaacgata gcattaagca agctcaagaa ctagcagact taactaaaac tattcgtaag
    67921 ttatcttatg ttaacttgat tccgtataat cctgtttcag aacatgatca gtatagtaga
    67981 agtcctaaag agcgagttct agcgttttat gatgtgctaa agaaaaatgg agttaactgt
    68041 gtggtgcgtc aagagcacgg aacagatatt gatgcagcct gtggccagtt acgttctaaa
    68101 acgatgaaaa aagatcgcga aaaggttaca gcgacaaaat aaagcccaaa aaatatcttt
    68161 gattgacaat gcttgatgac aaaatattcc tagtcactaa aatgactagg ttttttatct
    68221 ggcctaaaaa tgctctagaa gcacaatcca aaataatcca aaactaagat aaggaataaa
    68281 aggtatgcgc ttgatgccta atagtaagca agcagtaata cctgctaaac tagcaagttg
    68341 aattagccaa atcaacgaca ttagatccaa tactaaagct aagctagcaa ggtagaaaaa
    68401 atcgcctgct ccaattgaaa aaggtcttaa atgagctaat aaacctagta gcagtaatat
    68461 caatgataaa taattgatcg aataaaacag gagtagactt acaaagctaa aaagccacaa
    68521 gataaaaggg tattcttgag aacgccaatc aaataaacta aataataaag aaaagagtaa
    68581 caagtaacag taactagcac taacccaatg taccatacta gcccataaga taattattag
    68641 acttatctct aagctaaaga agattttttg gctagttata aaatggtttt ggaactgccg
    68701 aaaaacgcgt ttggcaaaag ttagttggtc acaaacaatg acagtctgtt tacttagctg
    68761 ttcttgacca ttatcaggaa aataaagtag taaacagtaa aaaagatggg tcaataagat
    68821 gcccgaacat atactaaaaa aagctatcat acttatttat tcgaaaagaa atcaaatact
    68881 tgcaatcttt ccttaatcat tgtagaatat agatataaaa cgataatgat tctaattaag
    68941 tgtctaatca tccaattagg attattccgt tattgtcgaa taggattagg tccttaaccc
    69001 tttcttatgt ttatcacgtt agggttagtt ccccctccat tcttgccctt taagctgaaa
    69061 agtaaggaga tgttattatg acaaacacac tcgttgaaaa tatttatgct tcagtaactc
    69121 acaatatttc taaaaaagaa gcatcaaaaa atgaaaaaac taaagctgtt ttaaaccaag
    69181 ctgtcgctga cttatctgtg gctgcatcta ttgtgcacca agtacactgg tatatgcgtg
    69241 gtccaggttt cttgtacctt caccccaaaa tggatgaatt acttgatagc ttgaatgcta
    69301 atttagatga aatgagcgag cgtttgatca ctattggcgg agcgccttat tctaccctag
    69361 ctgagttttc taaacactct aaattggacg aagcaaaagg tacttacgat aaaacagttg
    69421 ctcagcattt agcaagatta gtcgaagttt acctttacct cagcagcctt taccaagttg
    69481 gtttggatat taccgatgaa gaaggcgatg ctggaacaaa cgatttgttt acagcagcta
    69541 agacagaggc tgaaaaaacc atttggatgc tccaagcaga gcgtggacaa ggcccagcac
    69601 tctaattgat tatgccttag gataaaagaa gtcaatgata aaattggctt cttttttatg
    69661 gaatcatcga ttcattttca gaaacataga aagcgattcc atacttgtct tgaaatctgc
    69721 cgtagaattt gctaaaatct acttatatga aaacactata tgatgtgcaa caattgctaa
    69781 aaaactttgg catttttgtt taccttggca aacgtcttta tgatattgaa atgatgaaga
    69841 ttgaacttca gcgtctctat gatagcggct tattggataa gagggattac ttaaatgcgg
    69901 agttaatttt gcgacgtgag catagattag aattggaaaa agaaggatag acaaatgagt
    69961 caaaaattac tggggattga tttaggtggt accaccatta aatttggaat tttaacagca
    70021 gcaggagaag tccaagaaaa atgggcaatt gagactaata ttttagaagg aggcaaacat
    70081 attgtccctg atatcatcgc ttccatcaaa catcgtttag acttgtatgg tctaagcagt
    70141 gctgactttg tgggaattgg tatgggatca ccaggagcgg ttgaccgtga tactaataca
    70201 gttactgggg cattcaacct taattggaaa gaaacccaag aagtcggttc cgttgttgaa
    70261 aaagaattgg gcattccttt tgccattgac aatgatgcca atgtggctgc ccttggtgaa
    70321 cgttgggtag gtgctggtga aaataaccca gatgtcgtct tcatgacact tggaacaggt
    70381 gtcggtggag gcattattgc tgatggtaac ttgattcatg gtgttgcagg agcaggtggt
    70441 gaaatcggcc acatgattgt tgagccagaa aatggctttg cttgtacttg tggctcacac
    70501 ggctgtttgg aaacagtagc ttcagcaaca ggagttgtca aagtggcacg tttactggca
    70561 gaagcctacg aaggggattc agccatcaaa gcagctattg acaatggtga aggtgttacc
    70621 agtaaagaca ttttcatggc ggctgaagca ggggattcct ttgctgattc tgttgtggaa
    70681 aaggttggtt actaccttgg ccttgcttca gcaaatattt ccaatatctt gaatccagac
    70741 tcagtggtta tcggtggggg tgtgtcggca gcaggagaat ttctacgctc acgtattgaa
    70801 aaatactttg tgaccttcac tttcccacaa gtgaggtatt caactaaaat taagattgca
    70861 gagcttggca atgatgctgg aattatcggt gcagctagcc ttgctcgaca atttatcaca
    70921 aaataggagg gggatatgtc tccaatcaca cttatcttat ggttacttct tgtcggcatt
    70981 gttggttatt atacatggaa ctatttctct tttcgaaaaa tggcaaagca ggttgataac
    71041 gagactttta aagacgtgat gcgtcaaggt caattgattg atttacgaga gccagcggct
    71101 tttagagcta agcatatttt aggagctcga aattttccag cgcaacaatt tgatgctgct
    71161 attaagggac tacgcaagga caaacctgtt cttatttacg aaaatatgcg tccccagtac
    71221 cgtgtgcctg cggtcaaaaa acttaaaaaa gctggctttg aagacgttta tgtcttaaaa
    71281 gacggtattg attattggga tggcaaagtt aaacaaacaa cctagttaag agtaacgtgg
    71341 agttaagggg aataaaggca gtcactgtct caaaaacctt aattcctttt tttgctgtat
    71401 ccagacttgc tgaaagtctg aaaacattta caattgatta aaaccagttt tttaaaacat
    71461 tttgtgttat acttatctag ttaaaatata tttacttaga ggaacaaatg actaacttaa
    71521 gaaacgatat ccgtaacgta gcgattattg cccacgttga ccacggaaaa acaacacttg
    71581 tagatgaatt attaaaacaa tcccatactc ttgatgagcg taaagagctc caagagcgtg
    71641 ccatggattc caatgacctt gaaaaagaac gtgggattac aatccttgcg aaaaatacgg
    71701 cagtagccta taacgatgtt cgtattaaca tcatggatac cccaggacac gcggacttcg
    71761 gtggtgaagt tgaacgtatc atgaaaatgg ttgacggggt tgttcttgtt gttgatgcct
    71821 acgaaggaac aatgccccag acgcgtttcg tattgaaaaa agcacttgag caaaacctta
    71881 tcccgatcgt tgtggtgaac aagattgaca aaccttcagc tcgtccagca gaagttgtag
    71941 atgaagtgct tgaattattc atcgaacttg gtgccgatga tgagcaattg gaattcccag
    72001 ttgtttacgc atcagctatt aatggaacat catcattatc agatgaccct gctgaccaag
    72061 agcatactat ggcaccgatc tttgatacga ttattgatca tattccagcg ccagttgata
    72121 attcagatga gcctttgcaa ttccaagtgt cacttttgga ctacaacgat ttcgtaggtc
    72181 gtatcggtat cggtcgtgtt ttccgtggta ctgttaaagt gggtgaccaa gtaactcttt
    72241 caaaacttga tggtaccact aaaaacttcc gtgttacaaa actgtttggt ttcttcggtt
    72301 tggaacgtcg tgaaattcaa gaagctaaag caggtgactt gattgctgtt tcaggtatgg
    72361 aagatatctt tgttggagaa accattacac caactgactg tgtggaagct ctgccaattc
    72421 ttcgtattga tgagccaaca cttcagatga ctttcttggt caataactct ccttttgcag
    72481 gtcgtgaagg taaatggatc acgtcacgta aggttgaaga acgtctttta gcagaattgc
    72541 aaacagacgt gtcacttcgt gttgacccaa cagattcgcc agataaatgg acggtttcag
    72601 ggcgtggaga attgcattta tctatcctca ttgaaaccat gcgtcgtgaa ggctatgaac
    72661 ttcaagtatc acgtccagaa gttatcatca aagaaattga tggtgtcaaa tgtgaaccgt
    72721 ttgagcgtgt tcaaattgat acaccagaag aatatcaggg tgcaatcatc cagtctcttt
    72781 cagaacgtaa aggggatatg cttgatatgc agatggttgg taatggtcaa acgcgtttga
    72841 ttttcttgat tcctgcacgt ggtttgattg gttattcaac agagtttctt tcaatgacac
    72901 gtggatatgg tatcatgaat catacttttg atcagtatct accggttgtt caaggagaaa
    72961 ttggtggccg tcatcgtggt gccttggttt ctattgaaaa tgggaaagca acgacatatt
    73021 caatcatgcg tattgaagaa cgtggaacta tctttgtcaa cccaggtaca gaagtttacg
    73081 aagggatgat tgttggtgaa aactcacgtg ataacgacct tggtgttaac attacaacag
    73141 ctaagcaaat gacaaatgtc cgttcagcga ctaaagatca aactgcagtt atcaagacgc
    73201 ctcgtatcct aacgcttgaa gaatcattag agttcttgaa tgacgacgaa tacatggaag
    73261 taacgccaga atctatccgc ttgcgtaaac aaatcttgaa taaagctgcg cgtgataaag
    73321 ctaataaaaa gaaaaaatca gccgaatagc ttttaaagtt aaactaacta aataaaatag
    73381 caaaaagata tttaagaaaa gtcatttttt aaaggtcttt ttgcgtttac aagttcctat
    73441 ggaatataaa ccaaaataaa ggaggacgga atgttttacc ttattatggc tgtcttgatt
    73501 atatcttatt atctatacat ggctcctaaa agtgtccgta acacccttgg gatgattggt
    73561 ttagttggct tggttgctct gtttattgtt ttagcgggct tgagttttat caaaatcatg
    73621 caaacccctc ctgaattttt tattgggatg ggaatggtgg cattgggcta ttttgcttta
    73681 aaagatgtgc gtaaaatgac caaaaaaccg agagttaaat aaaaatactt aaagattgat
    73741 gattttggtt tttatacgat aaaaggactg atttgtttta gacaatatca gtcctttttt
    73801 aatagttcat tttttctgaa agaaagcttt tagccgattt tcattgagtg tgcaactaaa
    73861 aagagatgct tggtagtgac agttaagacc tctgactagt attttatctt attttactta
    73921 aaaaaacgta ccaataatct cacgaatatg ggcatgatgt ttgtatattg gaaacggatt
    73981 ctaattctaa actcaagaac ggtattttta aaatgttgaa aaagcatcta aataaaggta
    74041 aaatagaaat caaatagaat ggatagtgtg agcttagatg aaagtgataa gtaattttca
    74101 aaacaaaaaa atattaatat tggggttagc caaatcgggc gaagcagcag caaaattatt
    74161 gactaaactt ggtgctttag tgactgttaa tgatagtaaa ccatttgacc aaaatccagc
    74221 ggcacaagca ttgttggaag aggggattaa ggtcatttgt ggtagccacc cagtagaatt
    74281 attagatgag gactttgagt acatggttaa aaaccctggg attccttatg ataatcctat
    74341 ggttaaacgc gcccttgcaa aggaaattcc catcttgact gaagtagaat tggcttattt
    74401 cgtatctgaa gcgcctatta tcgggattac aggatcaaac gggaagacaa ccacaacgac
    74461 aatgattgcc gatgttttga atgctggcgg gcaatctgca ctcttatctg gaaacattgg
    74521 ttatcctgct tcaaaagttg ttcaaaaagc aattgctggt gatactttgg tgatggaatt
    74581 gtcctctttt caattagtgg gagtgaatgc ttttcgccct catattgctg tcatcactaa
    74641 tttaatgccg actcacctgg actatcatgg cagttttgag gattatgttg ctgctaaatg
    74701 gatgattcaa gctcagatga cagaatcaga ctaccttatt ttaaatgcta atcaagagat
    74761 ttcagcaact ctagctaaga ccaccaaagc aacagtgatt cctttttcaa ctcaaaaagt
    74821 ggttgatgga gcttatctga aggatggaat actctatttt aaagaacaag cgattatagc
    74881 tgccactgac ttaggtgtcc caggtagcca caacattgaa aatgccctag caactattgc
    74941 agttgccaag ttatctggta ttgctgatga tattattgcc cagtgccttt cacattttgg
    75001 aggcgttaaa catcgtttgc aacgggttgg tcaaatcaaa gatattacct tctacaatga
    75061 cagtaagtca accaatattt tagccactca aaaagcttta tcaggttttg ataacagtcg
    75121 cttgattttg attgctggcg gtctagatcg tggcaatgaa tttgacgatt tggtgccaga
    75181 ccttttagga cttaagcaga tgattatttt gggagaatcc gcagagcgta tgaagcgagc
    75241 tgctaacaaa gcagaggtct cttatcttga agctagaaat gtggcagaag caacagagct
    75301 tgcttttaag ctggcccaaa caggcgatac tatcttgctt agtccagcca atgctagctg
    75361 ggatatgtat cctaattttg aggttcgtgg ggatgaattt ttggcaacct ttgattgttt
    75421 aagaggagat gcctaatgcc taagaagatt ttatttacag gtggtggaac tgtaggtcat
    75481 gtcaccttga acctcattct cataccaaaa tttatcaagg acggttggga agtacattat
    75541 attggtgata aaaatggcat tgaacataca gaaattgaaa agtcaggcct tgacgtgacc
    75601 tttcatgcta tcgcgacagg caagcttaga cgctattttt catggcaaaa tctagctgat
    75661 gtttttaagg ttgcacttgg cctcctacag tctctcttta ttgttgccaa gcttcgccct
    75721 caagcccttt tttccaaagg tggttttgtc tcagtaccgc cagttgtggc tgctaaattg
    75781 cttggtaaac cagtctttat tcatgaatca gatcggtcaa tgggactagc aaacaagatt
    75841 gcctacaaat ttgcaactac catgtatacc acttttgagc aggaagacca gttgtctaaa
    75901 gttaaacacc ttggagcggt gacaaaggtt ttcaaagatg ccaaccaaat gcctgaatca
    75961 actcagttag aggcggtgaa agagtatttt agtagagacc taaaaaccct cttgtttatt
    76021 ggtggttcgg caggggcgca tgtgtttaat cagtttatta gtgatcatcc agaattgaag
    76081 caacgttata atatcatcaa tattacagga gaccctcacc ttaatgaatt gagttctcat
    76141 ctgtatcgag tagattatgt taccgatctc tatcaacctt tgatagcgat ggctgacctt
    76201 gtagtgacaa gagggggctc taatacactt tttgagctac tggcaatggc taagctacac
    76261 ctcatcgttc ctcttggtaa agaagctagc cgtggcgatc agttagaaaa tgccacttat
    76321 tttgagaaga ggggctacgc taaacaatta caggaacctg atttaacttt gcataatttt
    76381 gatcaggcaa tggctgattt gtttgaacat caggctgatt atgaggctac tatgttggca
    76441 aataaggaga ttcagtcacc ggacttcttt tatgaccttt tgagagctga tattagctcc
    76501 gcgattaagg agaagtaaat ggcaaaagat aaagagaaac aaagtgatga caagctcgtt
    76561 ttgacagagt ggcaaaagcg taacattgaa tttttaaaga aaaagaagca gcaagctgag
    76621 gaagaaaaaa aactcaaaga gaaattattg agtgataaaa aagcgcagca gcaagctcaa
    76681 aatgcttctg aagcagttga gcttaaaact gatgagaaaa ctgatagtca ggaaattgag
    76741 tcagaaacga cgtcaaaacc taaaaaaacc aaaaaagtta gacaacccaa ggaaaaaagt
    76801 gcgacacaaa tcgcttttca aaaatccttg cctgttcttt tgggggcgct cttactcatg
    76861 gcggtgtcta tttttatgat cactccttat agcaaaaaga aagagttttc tgtaagagga
    76921 aaccatcaaa cgaaccttga cgaattaatc aaagctagca aagtcaaagc atctgactat
    76981 tggttaacgt tgttaatttc gcctggtcag tatgaacgac cgattcttcg tactattcca
    77041 tgggtgaaat ctgtacatct ctcttaccac tttcctaatc actttctatt taacgttatt
    77101 gaatttgaaa tcatcgctta tgcacaagtc gaaaacggtt ttcagcctat tttggagaat
    77161 ggaaaacgtg tggacaaggt cagggcatca gaactaccga aatctttctt gattcttaat
    77221 ttaaaagatg agaaagcgat ccaacagtta gttaagcaat taacgacatt acctaaaaaa
    77281 ttagtcaaga atatcaagtc agtgtctctt gcaaattcca aaacgacagc ggatttacta
    77341 cttattgaaa tgcatgacgg taatgtagtt agagtaccgc agtcacaact cacattgaaa
    77401 cttccctatt atcaaaaatt gaaaaaaaac cttgaaaatg atagtatagt ggatatggaa
    77461 gttggaattt atactacaac acaggagatt gaaaatcaac ctgaagttcc tcttacgcca
    77521 gaacaaaacg cagctgataa agaaggagat aagcctggtg aacatcagga acagacagac
    77581 aatgattcag aaacgccagc aaatcagagt agtcctcagc aagcaccacc atccccagaa
    77641 acggtcctcg aacaggccca tggctagcta atatctaagt tgaaaaagca atgaaaacgt
    77701 tagaaattca acgattctaa cccataatga attgcctaaa aaaaattaag tttatataac
    77761 aaaaaacgta aaatgataac attttacgtt tttttatggt ataatatttt ctgaatgatt
    77821 ctgtttttta gcagttttta gaatagcaaa agtttggaaa gtaagtgagg tcaagtgaat
    77881 ggctagaaat ggctttttta ctggtttgga cattggaaca agctcgataa aagttttagt
    77941 agcagaattt atttctggtg agatgaacgt cattggtgtt agtaatgttc caagtaccgg
    78001 cgtaaaagat ggcataataa tcgatataga ggcagctgcg actgccatca aaactgcggt
    78061 agaacaagca gaagaaaaag cagggatgac aattgaaaag gttaatgttg ggctaccggc
    78121 aaaccttctt caaattgaac caacacaagg aatgattcct gtcccaagtg agtctaaaga
    78181 gataaaagat gaggatgttg atagcgttgt taaatcggct ttaacaaaaa gtatcacacc
    78241 agaacgagag gttatctctt tagttccaga agagttcatt gtggatggct ttcagggcat
    78301 tcgagatcca cgtggtatga tggggattag attagagatg cgcgggctta tttatactgg
    78361 accaagcacc attttacata atctgcgtaa aacggtagaa agagcaggca ttaaagttga
    78421 aaacatcatt atttctccgt tagctatggc taaaaccatt ttaaacgaag gtgagcgcga
    78481 gtttggagct actgtaattg atatgggagg tggacagaca actgtcgctt ctatgcgagc
    78541 acaagaattg cagtatacca atatatatgc tgaaggcggc gaatacatta ctaaagatat
    78601 atcaaaagta ttaaaaacgt ctttggctat tgcagaagca cttaagttta attttggtca
    78661 agcggagata tcagaagcta gtataactga aacagtaaaa gttgatgtgg taggtagtga
    78721 agagcctgtt gaggtaactg aacgttattt atctgaaatt atttcagcgc gtattcgtca
    78781 tattttagat cgtgtgaagc aagatttgga aagaggtcgt ttactagact taccaggagg
    78841 cattgttttg attggtggcg gtgcaatcat gcctggagtg gtagaaattg cacaagaaat
    78901 ctttggagta actgtaaagc tccatgttcc aaatcaagtc ggtattagaa atccaatgtt
    78961 ttcaaacgtt atcagtttgg tagaatatgt tggtatgatg tctgaagtag acgttttagc
    79021 acaaactgca gtttcaggag aagaactttt gcgacgcaag cctatcgatt tcagtggtca
    79081 agaatcttat ttaccagatt atgatgattc aagaagacca gaatcgacca ttggctatga
    79141 acaacaagcg tcacaaacag catatgattc acaagttccg agtgatccta aacaaaaaat
    79201 ttcagaacgt gttcgtggca tatttgggag tatgtttgat taaaagtaat aaagtgagga
    79261 gataaaatgg cattttcatt tgatactgca tcaattcaag gtgcaattat aaaagtaatt
    79321 ggagtcggcg gaggtggcgg aaatgccatt aatcgtatga ttgatgaagg tgttgctggt
    79381 gtcgagttca tcgcagcaaa cacagacatt caggcattaa gctcatcaaa agctgaaacg
    79441 gttattcaac taggccctaa attaactcgt ggacttggtg ctggaggaca acctgaagta
    79501 ggacgtaaag ctgctgaaga aagcgaagaa attttaacag aagctcttac aggagcggac
    79561 atggtattta ttactgctgg tatgggtggt ggctctggga caggggctgc accggttatt
    79621 gctcgtatcg ctaaaagttt gggagccttg acagtagctg ttgttactcg cccgtttggt
    79681 tttgaaggta acaaacgtgg taattttgct attgaaggta tcgaagaact acgtgaacaa
    79741 gttgatactt tgttaattat ttcaaataat aaccttcttg agattgttga taaaaagaca
    79801 cctttattag aagcacttag tgaagctgat aatgttttac gccagggagt tcaagggata
    79861 accgacttaa ttactagtcc tggccttatc aatctcgatt ttgccgacgt gaaaacagtt
    79921 atggcaaata aagggaatgc cttgatgggg attgggattg gttctggaga agagcgcatt
    79981 gttgaggcgg cgcgtaaggc aatctattca cccctattag aaacgactat tgatggtgca
    80041 caagacgtta ttgtgaacgt tacaggaggt ctcgacatga cactcacaga agctgaagaa
    80101 gcctctgaaa ttgttgggca agctgctggt caaggcgtta acatttggtt aggaacatct
    80161 attgatgata ctatgaaaga tgacatccgt gtgactgttg tagcaactgg agtgcgccaa
    80221 gaaaaagccg aacaagtttc aggttttcgt cagcctagga cttttaccca aaccaacgcg
    80281 cagcaagtag cgggtgcaca atatgcatca gatcaagcaa aacagtcggt tcaaccaggg
    80341 tttgatcgtc gctcaaattt tgactttgac atgggggagt ctcgcgagat accaagtgca
    80401 caaaaggtaa tttctaatca taatcaaaat caaggttcag cttttggaaa ttgggatttg
    80461 agacgtgata atatttctcg tccaacagaa ggtgaattgg ataaccatct taatatgtca
    80521 acgttctcag ctaacgatga cagtgatgat gagttagaaa cgcctccatt ctttaaaaac
    80581 cgttaataat ggatttactg acaaataaaa agaaaatttt tgagactatc cgcttatcta
    80641 cagaggcagc aaataggact actgatagtg tttcagttat tgctgtaaca aaatatgtgg
    80701 atagtacaat tgcaggtcag cttatcgaag caggaattga gcacattgcc gaaaaccgtg
    80761 ttgataaatt tcttgaaaag tatgatgcgt taaagtatat gccagtaaag tggcatttaa
    80821 tcggtacctt acaacgtcgt aaagtcaagg aagttatcaa ttatgtcgat tattttcacg
    80881 ctctagattc tgtgagatta gctttggaaa tcaacaagag agctgaccat cctgtgaagt
    80941 gttttctaca agttaatatt tctaaagaag agagtaaaca tggttttaac atttctgaga
    81001 ttgatgaagc gattgaagaa ataggtaaga tggagaagat acagttagtt ggtttaatga
    81061 ctatggcacc agcaaatgcc agtaaagaaa gtattataac tatttttcga caagcaaatc
    81121 aattaagaaa aaacttgcag ttaaaaaaaa gaaagaatat gccttttaca gaattgagca
    81181 tgggcatgag taacgattat ccaattgcta ttcaagaagg ctcaactttt attcggattg
    81241 gtagagcttt ctttcactaa tggagaataa gatggctttt aaagatacat ttaacaagat
    81301 gatttcttat tttgacacgg atgaggttaa cgaagttgaa gaagatgttg cagcatcaac
    81361 tgataacgtt attccaagat cacaacaatc agtcagagca agtagtcatc caaaacaaga
    81421 acctagaaac aatcacgtac aacaagatca tcaagcgaga tcccaagaac agacaaggtc
    81481 acaaatgcat ccaaaacatg gtacttctga acgctattat cagcagtctc agccaaaaga
    81541 aggccatgaa atggttgaca gaagaaaacg gatgagcact tctagtattg caaatcgccg
    81601 tgagcagtat caacaatcaa cttgttcaga tcaaacaact attgccttaa agtatcctcg
    81661 taaatatgag gatgctcaag aaattgtgga tcttttaata gttaatgaat gcgttttgat
    81721 tgattttcag tttatgctag atgctcaggc tagacggtgt ttagatttta ttgatggtgc
    81781 tagtaaagtg ctctatggta gcttacaaaa ggtcggctct tcaatgtact tactggctcc
    81841 gtcaaatgta tccgtcaata tagaagaaat gactatccca catactacac aagatattgg
    81901 ctttgatttt gatatgaaaa ggcggtaaat aaatgatatt aatactatct attcttcttc
    81961 gtctgatcaa agtttacact tatttattga ttgcttacgc attaatgtca tggtttcctg
    82021 gggcatatga ttcaaaaatt gggcgtttga ttagtggtat cgttgaacca attttaaaac
    82081 cttttagagc atttaattta caatttgccg gtcttgactt cactattttt gtcgtcatta
    82141 ttagtttgaa ttttttagct caagttttgg tccgtgtgtt tatttaatgg ttagtcatag
    82201 taagatttat cagcattttc accaagaaga atatcctttt attgatagaa tgtctgatat
    82261 gattaataga gttgaagatt actatctttt agaagttact gagtttttaa atcctagaga
    82321 agtgatgatt ttaaaaagtt tgattgcttt aacagatcta aaaatgttcg tatcaacaga
    82381 ttactaccca agcgaatatg gtcgtgtcat tattgcacct ggttactatg acttagaaca
    82441 aagtgatttt caaatagctt tagtagagat aagttatcag gcaaagttta atcagttgac
    82501 acatagtcaa attttaggaa ctttaattaa tgaattagga gtaaagcgaa atttatttgg
    82561 agatgttttt gttgaaatgg gatatgccca gctcatgatt aagcgggagt tattggatta
    82621 ttttttagga acaattacta aaatagctaa aactagtgtg aaattaagag aagttaactt
    82681 tgatcagtta attaggtcta ttgataacag ccagaccctg gatattctag tttctagttt
    82741 tcgattagat ggtgtagttg ctactatctt aaaaaaatct cgaacgcaag ttatagcatt
    82801 aattgaagca aataagatta aggtaaacta tcgactcgct aataaagctt cagataatct
    82861 agtcataggg gatatggtga gtatcagagg tcacgggcgt tttactcttt tagcagataa
    82921 tggagtgacc aaacatggca aacaaaaaat aacactaagt aaaatgatac ataaataagg
    82981 agatacaatg gcacttacaa cgctagaaat taaagataaa acttttaaga caaaattccg
    83041 aggatactgt gaagaagaag tcaatgaatt ccttgatatt gttgttgatg attacgaagc
    83101 tcttgtacgt aaaaatcgtg ataacgaagc aagaattaaa gatcttgaag aaaaattatc
    83161 ttactttgat gaaatgaaag agtcacttag ccagtctgta atcttagctc aagaaacagc
    83221 tgaaaaagtg aaagcaacgg ctaatgcgga agcaacaaac ttggttagta aagcgactta
    83281 tgatgctcag catttattag atgaatctaa agctaaagcc aatcaaatgt tgcgtgatgc
    83341 aactgatgag gctaagcgag ttgcgattga aacagaagaa ttaaagcgtc aaacacgtgt
    83401 gttccaccaa cgtttaatct catctattga gtcacaatta agcttatcaa attcacctga
    83461 atgggatgaa ctgttacaac cgactgcaat ctatcttcaa aattctgacg atgcttttaa
    83521 ggaagtcgtg aagaccgttc ttaatgaaga cattcctgaa tctgatgata gtgcctcttt
    83581 tgatgcaaca cgtcagttta ctccagaaga gttagaagaa ttgcaacgtc gtgttgatga
    83641 aagcaataag gagttagagg cttaccaact tgactctcaa tctgattcta cgactgagcc
    83701 agaggtaaat ctcagtgaaa cacaaacgtt taaattaaat atctaaataa agaaaaacaa
    83761 gatgatttgc ttataatcac agcaagcggg agatgatgag agtctcgtat tccctaagta
    83821 ttatcattat cattttctaa aattttcgct gaactacagt aagcgaggag gtttgttcac
    83881 cttacgagca aagagggagc ggtaagtctt atgatatatt atcgctctga actaaggtgg
    83941 taccacgagc tttcgtcctt tttgagacga ggcttttttc gttatagtcg caagtttgtt
    84001 taaaaggagt ttgaaataat gaaattaaaa gagacactta atctaggaaa aacagccttt
    84061 ccaatgcgcg caggtcttcc taataaagag ccacaatggc aagcagcttg ggaacaagca
    84121 gagctttaca aaaaacgtca agaattgaat gcaggtaagc ctgcctttca tcttcatgat
    84181 ggacctcctt acgctaacgg caatattcac gttgggcatg cccttaataa aatttcaaaa
    84241 gatatcattg tgcgttctaa gtccatgtct ggctttcaag cgccttatgt accaggttgg
    84301 gacacacacg gccttccaat cgaacaagtc ttggctaagc aaggaatcaa acgtaaggag
    84361 atggatttag cagaatacct tgagatgtgc cgtcaatacg ctttaagtca ggttgataaa
    84421 cagcgaaatg atttcaaacg gttaggtgtt tcggcagact gggaaaatcc ttatgtcact
    84481 ttggacccac agtttgaagc tgatcaaatt cgtgtttttg gagcgatggc tgaaaaaggt
    84541 tacatctatc gtggtgctaa acctgtttat tggtcatggt cttcagaatc ggccttggca
    84601 gaagctgaaa ttgaatacca tgacatcgat tcaacctctt tatactacgc caataaagtt
    84661 aaagatggta aaggcatcct tgatactaat acgtatatcg ttgtttggac aacaacacca
    84721 tttacggtta cagcatcacg cggtttgact gttgggcctg atatggatta tcttgtggtg
    84781 aaacctgctg gttcagaccg tcaatatgtt gtggcagaag gtctttcgga tagccttgct
    84841 ggaaaatttg gctgggaatc ttttgaaact ttagccagcc ataaaggagc tgatttagag
    84901 tacattgtga cagaacaccc atgggatact gacgtagaag aattggttat ccttggtgac
    84961 catgttaccc ttgagtcagg gacagggatt gtccacacag caccaggttt tggtgaggat
    85021 gactacaatg ttgggacaaa atacaaactg gaagttgctg tgactgttga tgaacgtggc
    85081 ctaatgatgg aaaatgcagg tccagatttc cacggacaat tttataacaa ggtaacgccg
    85141 attgtcattg ataaacttgg tgatctttta ttggcacaag aagtgatcaa tcactcttac
    85201 ccatttgact ggcggacgaa aaaaccaatc atctggcgtg ctgtaccgca atggtttgct
    85261 tctgtttctg atttccgtca agatattttg gatgaaattg aaaaaacaac cttccatcca
    85321 tcatggggtg aaacacgcct ttacaatatg attcgtgatc gtggcgactg ggttatttct
    85381 cgtcaacgtg cttggggagt tccgcttcct atcttctatg ccgaagatgg cacagctatt
    85441 atgactaaag aagtgacaga tcatgtggct gatttgttcc aagaaaatgg atcaatcatt
    85501 tggtggcaaa aagaagctaa agacctatta ccagagggct tcactcatcc agggtcacca
    85561 aatggcgagt ttacaaaaga aactgatatc atggacgttt ggtttgactc tggttcttct
    85621 tggaatggag tcatgaatgc tagagaaaat ctttcctatc cagcggatct ctacttagaa
    85681 ggctctgacc agtatcgtgg ttggttcaat tcatccttaa ttacatctgt ggctgttaat
    85741 gggcatgctc catataaggc tattttatcg caaggctttg ttcttgatgg taagggcgaa
    85801 aaaatgtcta aatcaaaagg caatatcatt tctccaaatg atgtggctaa acaatatggt
    85861 gcagatattc tccgtctctg ggtagcttct gtggataccg ataatgatgt tcgtgtttct
    85921 atggagatcc ttggtcaagt ctctgaaact taccgtaaaa tccgtaacac ccttcgcttc
    85981 ttgattgcta atacatctga tttcaaccct gctacggata cagtagctta tgcagactta
    86041 ggagctgttg ataagtacat gacaattgtc tttaatcagt tggtagcaac gattactgac
    86101 gcttatgagc gttatgactt tatggctatt tacaaagcag tggtgaactt tgttacggtt
    86161 gatttatcag ccttctatct tgattttgct aaagacgttg tctatattga agctgccaat
    86221 agcttagaac gtcgtcgcat gcagacagtc ttctatgata tcttagttaa gattaccaag
    86281 ttattgacgc caatcttgcc tcacactact gaagaaatct ggtcttatct agagcatgag
    86341 tcagaagcat ttgttcaatt gacagaaatg cctgtggcag aaaccttctc agctcaagag
    86401 gatattttag aagcttggtc agctttcatg actttgcgta cccaagctca aaaagctttg
    86461 gaagaagcgc gaaatgccaa ggttattggg aaatcattgg aagctcattt gactatctac
    86521 gctagcgaag aagtgaaaac cttattgact gctttagaca gcgatattgc tttgcttttg
    86581 atcgtgtctc aattaaccat tgctgacttg gcagatgcgc ctgcggatgc cgtagcattt
    86641 gaaggtattg cctttatggt agaacatgcc ataggtgaag tttgtgagcg ttcacgccgc
    86701 atcgacccaa ctactcgcat gcgttcttac aatgcatttg tctgtgatca cagcgctaaa
    86761 atcattgaag aaaatttccc agaagctgtg gctgaagggt ttgaagagag tggcaaataa
    86821 gtcttatcaa gacttgaagt gacactgagt aagaagacaa ccatcgggtc ttaggacctg
    86881 atggtttttt agtagagctg attacgtcca ttagccagct ttaacgagag acaaagtagg
    86941 agaaatttag actacttttt taatttcttt taagaaaatt gctggctcca tataaggact
    87001 attaagatag agttcacctt tcgctaataa aaaaacttag ctctgttaga agggctaagt
    87061 tttgtctgaa tagctggctg ctgtttatac agaagtttga aatgaaattt caataaggtt
    87121 attcgtgtga agtgtttttg attgtccagg aataacaatt ttaggatcaa ttttacgttt
    87181 taaaaaaaat tcgcgaatga tatcaagttc atcctccttg atggcacggt atttatttga
    87241 aataagtagt tcgtaatgtt ttggtgcttg ggtaaaaatg acatctgtat tccctgctga
    87301 gtatacttcg actaaatagg catcggtgtt ttttagctga tttctgatga gttctgggtg
    87361 actgctagtg gtattgatga gtctcataaa tgtcctcctt agtattcctg tacctattat
    87421 agcactaatt taaagcctta gttagtagaa tgatgctttt tttgccattc cttgactccc
    87481 cattgatggc tctctcgttt taatttagca attgcctcga taggagaaaa ccaacctaag
    87541 ttattaaaat cttctaaggg cttagaaacg gcttgaaatg cggttacttc ataaagatag
    87601 gcaggatggt agaagtgggt atcacgatgg cgagagtaga aatattcatc agcctgaccg
    87661 taatatgaac caatagtagc agaaaaacca agttcttcaa tcagttcacg ctctagggcc
    87721 tgaagctgac cttcacctgc ttcaatttca ccaccaggta aaaaccagga accattagga
    87781 gcttgaacaa gaataatttt tgtttgttcg tgattgggaa tgatagcata gacaccgtaa
    87841 cgtgtgacat agtctttatg tgcattttta tgtccaaatg ttggaatcat cattttattt
    87901 acctttcctt tttcttcatt atactaaatt tttgctaatt attcttatca atttgtttag
    87961 tttaataaaa aattgataga aaaagagaga gtctccttat agaaactctc ttagctaacg
    88021 ttaatcgaga gactcttcgt taagaaaaga atttccctct ttaacagctt taatcgtgat
    88081 attttcactg tttgtcatca gtgcacgtaa ctgtttttca gttgggtgct ctaaataata
    88141 gtctgtaatg gcatcttcta tataatcttg gatagtacga cggagcggcc gagcgcccat
    88201 tttaggatca tagcctaaat ctactaattt ttctttgacc ttttgtgtca catcaagatg
    88261 aatcccatta tagcctaagc gctcattaac atcttccagc attaaatcaa cgatatgcag
    88321 caaatgctct ttagataaag ctttgaattc aataatacca tcgaaacgat tcataaactc
    88381 tgggctgaag aagttgctta attcaccaag gacagaactt gtccgtcctt ctctagcagc
    88441 accaaatccg acagaagctt cgcttttacc tgttccggca ttagaagtca tgataataat
    88501 ggtgtccttg aagctgactg ttcgtccttg accatctgtt aaacggccat catcaagaac
    88561 ttgtaagaac atgtgcatga cgtcaggatg ggctttttcc acctcatcta agagaataag
    88621 tgaatatgga ttgcgacgaa cttgttcggt tagctgtcca gcttcttcat agccgacata
    88681 acctggagga gccccgacta atttggcgac agcgtgtttt tccatgtatt cggacatgtc
    88741 aaagcgaatc atattgtttg tcgaaccaaa gagttcaatg gctagttgtt tagacaattc
    88801 agttttacca accccagtcg gtccaacgaa taagaaagaa ccaatagggc gatttggagt
    88861 tcctaatccc acacggttac gacgaatagc cttagcgatt ttatcaacag catcgtcttg
    88921 cccgatcacg tgtgctttca gatcattggc taagtttacg agttgagact gttccttttc
    88981 ttttaagtcc ccaactggaa tattagtttt ttgctctaca atagcttcaa tggttttttc
    89041 agtaatgatg ggaatatctt gctcatcgac tttttgagcc tgcatttctt tgtattttgt
    89101 aatttgatcg cggaaataag ctgcgcgttc atagtcttcg tctcgagtag cttgcgcctt
    89161 gagattctca gcttcaataa gacgtttgtc aatttcttta ggatcaacaa agttgagggt
    89221 tagattcatt ttggaaccag cctcgtccag aaggtcaata gccttatcag gaagaaaacg
    89281 gtcttgaata tagcggttag ataaatgagc agcagcttca atagcggctg ggctatattt
    89341 gacatgatga tagtcttcgt atttcggttg gatacctttt aaaatcgtga tggtttcctc
    89401 aacagaaggt tcatcaactt taacgggttg catccgtcgt tctaaggcag cgtctttttc
    89461 aataatacgg tattcattta aggtggtagc gccgaccaac tgcaactcac cgcgggccaa
    89521 ggctggtttt aaaatattac cagcatccat attgccgtct cctgcagaac cagcaccgac
    89581 aatctcatga atttcatcaa taaagagaat cacatccttg cgattgcgaa tttcttccat
    89641 taatttttgc atgcgctctt caaactgacc acggatacct gttccctgaa cgaggctaac
    89701 cacatcaaga cgaatcactt gcttgccttg gagtttttga ggaacagtac catcaataat
    89761 tttttgagcc aaaccttcta caacagcagt tttaccaact ccaggctcac caattagcac
    89821 aggattattt ttagtacggc ggttgaggat ctcgataacg cgtgtaatct cttcgtcacg
    89881 accaataaca ggatcaatat taccatttct tgcaatatct gtgacattaa tcccaaactc
    89941 ttctaacaag ccctttgctt gctgatttgg tgtttgtggc tgagcaggtc gttgtccgtt
    90001 gtagttacca ccatagcgtc ctccgccatt tccattttgc cctgcctgag taggtggggt
    90061 atttggaaga ttaccaaaag ctctaaaatt attcaaatca ccaaaaaagt catcaaagaa
    90121 aggacttgtg gatctatctt gtgctctata tcctggggtt aggccattta aaatagaatt
    90181 ggcaggatcg gatttcatga tttgataaca attttgacag agatcaacct gtctttgttt
    90241 tccattaaca cttgtataaa gatgaatagt agattcgttt aaattacaat tttgacacag
    90301 cataatatac ctccgagggt ttatctaaaa gtcaaagtca tttagtcaaa aatggtcaaa
    90361 ctttatattc atattatagc accacggctt gggaaatcaa gtaaaaagtt tatcgcttta
    90421 gcgttagctt ttagagagta acatgacaga gtaactttat taagtttcca atgagcaaat
    90481 gtttaaaatc attgaaaaga gtaaaaaaag taaaatatca ataaatatat tactttcctt
    90541 gttagtttcc cttgttttgt gttaaaataa gagggataaa aaacgaatag gagaaacgaa
    90601 atggaatcac atttggtgag aatcatcaat cgtttggagt tgatggtgac agatggcggt
    90661 aatctcaagc gaaattttga acgcgatggt gttgttgttg cagaagttgc cttttcaaat
    90721 gatcctgaaa atggacctgt tttcacattg cgtgatgttg aagcgcgtga gtcatattcc
    90781 tttgatagta ttgacttgat tgcaatggaa atctacgatt tattatatta agcttgacat
    90841 agtaaagaga cttgcctgag gcaggttttt ttattgtcaa aaagtattgt attaatattc
    90901 atcagatggt ataattatct ttattgtaat gaacctagga cttatgagga gatataaatg
    90961 gatttgtcat ttttgcccaa atactgggcc tactttaact acggtgtact tgtcaccatt
    91021 atgatttcag tcagcgttgt cttttttgga acccttatcg gtgtcttggt aaccctgatt
    91081 aagcgtagtc atgtgaagcc gttgacctgg gtcgttaatc tttacgtttg gatctttcgg
    91141 ggaacaccta tggtggttca aattatgatt gcctttgctt ggatgcattt taataatatg
    91201 cctactattg gttttggggt tttagacttg gacttttcaa gactacttcc tggaattatt
    91261 atcatttcat tgaatagcgg tgcttatatt tcagaaattg ttagagcagg tattgaggct
    91321 gtaccaaaag ggcaattaga agcagcttat tcactaggta ttcgtcctca aaatgccatg
    91381 cgttatgtga ttttgcctca ggcctttaaa aatattttgc cagccttagg aaatgaattt
    91441 attaccatta ttaaggatag tgctctttta caaaccattg gagtgatgga actttggaat
    91501 ggtgctcaat cagtggtaac ggctacttat tctccaattt cccctttact ggtggctgct
    91561 ttttactact taatggtcac aacagtgatg gcacagttat tggcagtctt agaacgtcac
    91621 atggcgcaag gaggtaatca ttgatgactg aggctattat ttcaattaaa gacttgcaca
    91681 agtattatgg gcacaatgaa gtgcttaagg gaattgattt agacattatg ccaggagagg
    91741 ttgtggtgat tattggcccg tctggttctg gaaaatcgac cttacttcga accatgaatc
    91801 ttttggaagt accaactaag ggacagatta ggtttgaggg gattgatatt accgataaga
    91861 agaatgatat tttcagcatg cgtgaaaaaa tggggatggt ttttcagcag tttaacctct
    91921 ttcccaatat gactgtttta gaaaatatca ctttatcgcc aatcaaaact aagggaatgg
    91981 ctaaagcaga ggctgacaaa acagccttga gcttgttgga caaagttgga ttatcagaaa
    92041 aagccaaggc ttatcctgct agtctttctg gtgggcaaca gcagcggatt gcgattgcgc
    92101 gtggactggc tatggatcca gatgttttac tctttgatga accaacttca gctctagacc
    92161 cagaaatggt gggtgaggtc ttggctgtca tgcaagattt ggctaaatct gggatgacta
    92221 tggttattgt gactcatgaa atgggctttg ctaaagaagt cgcagaccgt gtgattttta
    92281 tggatggcgg cgttattgtg gaagaaggaa gtcctaacca actttttgat ctgactaaag
    92341 aagaacgtac aaaagatttt ttgagtagag tattataaat ctgttctatg aattataaaa
    92401 ggaagtccta aatgatttag gacttccttt tataatttgc taaggcattt tataggagat
    92461 tacttttctt tttgttaaaa taaaaagaaa tagttgcatt atttgcatag aagaaaggga
    92521 tctgttatgg tttcagtgat gtggtttcgt agagatttaa ggattgatga tcaaaaagct
    92581 ttagctcatg ctattgctag tcaatcacca accttatgtg tgtttcaatt taacaaggag
    92641 caattaaatc tgctacatag tcggaatcaa tctagtttta ttactagcgt tttggctttt
    92701 agaaagttat taaaatgtga aggtattgac ttatatctaa tgtatggaga cttaatgacc
    92761 tgttttgagc aattattgac acaattaaaa gactggacag atgtgtattt taactatgat
    92821 gaatctggat atggtcgttt acgtgatcaa aaagcagcac aatttttcaa aaaaaatggg
    92881 attgctgttc atacctacca agatcactat ttacatggta gtcaagagat cattaaccaa
    92941 tcaggtcagc cttataaagt ttttacgccc tactatagga tttggcaaaa ttatccgaaa
    93001 gagactccta ttaaagtaga actatcgcaa ggcaggtggt taaatcttga gacaccagat
    93061 gatgttttaa ggactgttga gagctttaaa gatgaaaaat atcaggatgt tgcaactttt
    93121 gatgaagcgt caaaacaact aaatcgattt attcaagacc aattagcagc ttatcacgct
    93181 aatcgagatt ttccagcgca gctagggacg agtcggttgt ctcctttttt aagaatagga
    93241 gctattggca ttcgcacggt atatcacgct gtgcgtcaag caccaaatag tctagggcaa
    93301 gctacttttt taaaagaatt agcttggaga gacttttaca atatggtcta tgtggcttat
    93361 cctgatcaga aaactcagcc tatccaaaaa gccttttctc aaatcgaatg ggttaataat
    93421 cctgactggt ttcagttgtg gaaagaaggt aaaacgggtt accctattgt tgatgctgcc
    93481 atgcttcagt tacaaaagac aggatggatg cataatcgtt tacgaatgat agtagcttct
    93541 tttttaacta aagatctttt atgtgattgg cgtttaggag agcagtattt tcaacaacaa
    93601 ctaattgatt atgatgctgc cagtaatatc ggaggatggc agtgggctgc ttccactgga
    93661 acagatgctg ttccttattt tagaatattt aatcctgtta ctcaaggtaa gcgttttgat
    93721 cccaaaggcg agtttattaa agcgtatttg cctcaactag aacacgttcc agagaagtat
    93781 ctccacgaac cgtggaagat gccaaaatac cttcaagaga gtgtatcctg tattattggc
    93841 acagactatc ctcaaccaat tgtcgatcat gctaaacaac gtgaacaagc tattgcaaag
    93901 tatgagtggg caaaagaaaa agcaaaaata gaatgactgt tctcattata agagtttaaa
    93961 caaaaagtta tcatgaatta agattattta atttaaaaaa taagttgact ttatttagat
    94021 tatttgatac tattcagttg tctcccttag agaaagcgat ttcttgtttt ggagctgatt
    94081 tttaccattt ggtcttagaa taggatgagt aatatgactt acaacgaggt atatcaagaa
    94141 tggttgcaca ataatgatct tagtgatgat attaaagcag atttagcagc cataaaagac
    94201 aatgaggctg agattcaaga tcgtttttac aaaacacttg aatttggaac agcagggcta
    94261 agaggaaaac ttggagcagg caccaatcgc atgaatacct atatggttgg taaggcagca
    94321 caagctttag ctaatactat tattgatcat ggacctgaag cagttaaaaa gggcattgcg
    94381 gttagttatg atgttcgcta tcaatctaga acatttgcag aattaacatg ctctattatg
    94441 gcagctaacg gtattaaggc gtacctttat aaagggattc ggccaacacc aatgtgttcg
    94501 tacgctattc gtgctttggg atgtatctct ggtgttatga ttacggctag tcacaatccc
    94561 caagcttaca atggttacaa agcttattgg caagaaggtt ctcaaatttt ggatgacatt
    94621 gcggatcaaa ttgcacaaca catggctgca ctaactcagt atcaggaaat caaacaaatg
    94681 ccttttgaaa aggctctgga cagtggactt gttacttata ttgatgagag tattgaagaa
    94741 gcatataaaa aagaagtgct tggtttaacg attaatgata ctgacattga taagtcagtc
    94801 cgagtagtct atactccttt aaatggtgtt gggaatctac cagtgcgtga ggttttaaga
    94861 cgccgcggtt ttgaaaatgt ttatgtggta cctgagcagg aaatgcccga tcctgatttt
    94921 acgacagttg gctatcctaa tcccgaagtc cctaaaactt ttgcatattc agaaaaatta
    94981 ggtaaggcag ttgatgctga tattttgatt gcaactgatc cagattgtga ccgtgtggct
    95041 ttagaagtta aaaacgcagt cggtgactat gtttttctca atggcaataa aatcggagcg
    95101 cttttatctt actatatctt ttcacaacga tttgacttag gtaatttacc ggctaatcct
    95161 gttttagtga aatccattgt aacaggagac ttgtcacggg ctattgctag ccattatggt
    95221 attgaaaccg ttgaaacatt gactggtttt aagaatattt gtggcaaggc aaacgaatat
    95281 gatgtgacga aacagaaaaa ctatctgttt ggttatgaag aaagtattgg tttttgctat
    95341 ggcacttttg ttcgtgacaa agacgctgtt agcgcctcta tgatgattgt agaaatggca
    95401 gcttactaca agaaaaaggg gcagaattta ctagatgttt tgcagactat ttatgcgaca
    95461 tttgggtatt ataatgaacg tcaaattgcc ttggagcttg aggggataga aggacaaaaa
    95521 cgcattgcga ggataatgga agatttcaga cagacaccaa tagctagtgt tgcagagatg
    95581 gcgttagaca agacaattga ttttattgat ggctatcaag attttccaaa gcaaaactgt
    95641 ctcaaatttt atttggatga tggttcttgg tatgcactta gaccatcagg aacagagcct
    95701 aaaataaaat tttatttata tactattggc caaacacaag aaaatagtgc aacaaaatta
    95761 gatgctattg aatcagcgtg tcgcacaaaa ataaatcagg ttaattaaac atcaaaaatg
    95821 gataacactt ttacactatt tttccatata aacaactaca aaaggaggtg agacttttag
    95881 gcaccttctt tttcttgtag gtgccactaa ccaatttaat cgactcaaac caatactaaa
    95941 aaataagtaa gagtataaag aacaggcatc tatttttttg ttataataga aaaatgaaat
    96001 taaagggaga tgtcaatgac agaactaatt gatggtaaag ccttagctca aaagatgcaa
    96061 caagagttag cagctaaagt caacaatcta aaacaaaaaa aaggaattgt accaggctta
    96121 gccgttattc ttgtaggtga tgatcctgct agtcaggtgt atgtccgtaa taaagagcgt
    96181 gcagctctta ctgtaggttt taaaagtgag accgttagat tatcagaatt catttgtcaa
    96241 gaagagctta ttgcagtaat cgaacgttac aatgcagata acactattca tggtatttta
    96301 gtgcagctac ccctgccaaa tcatattaat gataaaaaaa ttattctcgc cattgatccc
    96361 aaaaaagatg tggatggttt tcacccgatg aatacaggtc atctttggtc aggacgtccc
    96421 ttgatggttc cttgtactcc atcagggatt atggaattgc ttcgagaata taatgttaac
    96481 cttgaaggta aacatgccgt cattattggc agatcgaata tcgttggaaa accaatggca
    96541 cagctcttac tggacaaaaa tgcaacagtc acgttgacac attcaagaac acgtcaatta
    96601 gaagaagtat gtcgctgtgc agatgtgttg attgtggcaa tcggacaagg tcatttcata
    96661 acaaaacaat atataaaaga tggtgcgata gtgattgatg tgggaatgaa ccgtgatgat
    96721 aatggcaagc taattggaga tgtggccttt gatgaggtgg cagaagttgc agcgaaaatc
    96781 acccctgtac caggaggtgt cggtcctatg acgattgcta tgttgctaga gcaaacttat
    96841 caatctgctc tccgtagtac tcataaatag ttataattag acaattcaac ataagagaat
    96901 ataagaagtc agcaatggct tccttttttg tttttctgct cactatttat ccagaaaaat
    96961 ggtataattg cattagtatg caaagggact atgtcaggtc caactaagtg aaaggtggct
    97021 tgatggcaga ttatttaacc gtcactcatt tgacgaaata tttaaaatta aaatttgacc
    97081 gtgaccctta tttggaacgg gtttatctga ctggtcaagt gtccaatttt cgaaaacgac
    97141 caactcatca atatttttcc ttaaaggatg aaagtgctgt gattcaagcc accatgtggg
    97201 caggagtcta taaaaaacta ggattcgacc tagaagaagg catgaaaatt aatgtaattg
    97261 ggcgagtcca actttatgaa cctagtggct cttactctat cgtgattgaa aaggcagagc
    97321 cagatggtat aggtgccttg gctttgcagt ttgaacaatt aaagaaaaaa ttaacggcag
    97381 aaggttattt tgagcaaaaa cacaagcagc ccttgccaca gtttgtatca aaaattgggg
    97441 tcattacaag tcctagtggt gctgtgattc gagatattat cacaaccgtt tcacggcgtt
    97501 ttccaggggt tgagatttta ttattcccaa ccaaagtaca aggtgatgga gccgcccaag
    97561 aagtagtggc taatattcga agagccaatc aaagagagga tttggacttg ctcattgtcg
    97621 gccgtggagg tggctcgata gaagaccttt gggccttcaa cgaggaaata gtggttcagg
    97681 ctatctttga atcgcaactt ccggtgattt cgagtgtggg tcatgaaaca gacacgactt
    97741 tagcggattt tgtggcagat cgcagagcag ccacaccaac agcagcagca gagttagcaa
    97801 cgcctattac aaaaacagat cttatgtctt ggatagtaga gcggcaaaat cgttcctatc
    97861 aggcctgctt gaggcggatt aagcaacggc aagagtgggt ggataaactc tcgcaatctg
    97921 ttatttttaa gcaaccagaa cgattatatg atgcctacct gcaaaaaatt gatcgcctta
    97981 gcatgaccct gatgaatacg atgaaagatc gtctgagttc cgccaaagaa aacaaggttc
    98041 agttggacca tgccttggcc aatagtcaat tacagacaaa aatcgagcga taccaagacc
    98101 gtgttgctac cgctaagcgt ttactgatgg ctaatatggc tagtcaatat gatagtcagc
    98161 tggctcgctt tgaaaaagca caggatgctt tgctatcact ggatgccagc cgaattatcg
    98221 cccgtggtta tgcaatgatt gaaaaaaatc aagcactggt agcctctgta agtcagataa
    98281 caaagggtga tcagttaacc attaagatgc gtgatggaca attagatgta gaggtaaaag
    98341 atgtcaaaaa cgaaaacatt tgaagaaaat ttacaagatt tagagactat tgtgaacaaa
    98401 cttgaaaatg gggatgtccc tttggaagaa gctatttcag aatttcaaaa aggaatgctt
    98461 ctctcaaaag aacttcaaaa gaccttacaa gcggcagaaa aaacactcgt caaagtgatg
    98521 caagctgatg gcacagaagt agatatggat gattaatgga caaattagct agaattgacg
    98581 aagccattcg tcgctactat aagaagacta gtaacggtgt atctgaagag ttgattgatg
    98641 ctatcttgta ttctgttgac agtggtggca agcgcattcg accacttatc ttattagaga
    98701 tgattgaggg atttggggta tcgttacaga atgctcattt tgatttggct gcagcccttg
    98761 aaatgattca tacaggaagt ctgattcacg atgatttgcc agccatggat aatgatgatt
    98821 accgacgtgg tagactgacc aatcacaaac aatttggaga agctacggcc attttggcgg
    98881 gagatagctt atttttagac ccctttgggt taatagctca agctgaatta aatagcgagg
    98941 ttaaagtagc cttaatccaa gaactttccc tagcttcagg aacttttggc atggttggtg
    99001 gtcagatgct agatatgaaa ggggaaaatc aagctttgag tctccctcag ttgtcactga
    99061 ttcacctcaa taaaaccgga aaattattaa cttttccttt taaagcagca gctcttgtaa
    99121 cagaacaggc tattactgtt cgtcaacaac tagagcaggc gggaatgctc atcgggcacg
    99181 cctttcagat tagggatgat attttagacg tgacagctag ctttgaagat cttggaaaaa
    99241 cgcctaaaaa ggatttattt gcagaaaaag ctacttaccc aagtttactg gggttagaag
    99301 cctcctacca actgttgaca gagagtttag atcaggcttt gacgattttt cagacactcg
    99361 aaagcgatgt aggctttaag cctcaaataa ttacaaaact gatagaaggg ttacgactta
    99421 atgcctaaag aaagagtaga tgtgttagcc tataagcaag gattatttga gaccagagag
    99481 caagctaagc gtggtgttat ggcaggctta gtggtctctg tgattaatgg ccaacgctat
    99541 gacaagccag gtgacaaaat tgacgatggg actgagttaa aacttaaagg tgaaaaactc
    99601 aaatacgtca gtcgtggtgg attaaaactg gaaaaggggc tgcacgtttt tggtgtatcg
    99661 gttgctaatc aaattgggat tgatattggc gcttcaacag gtggttttac cgatgttatg
    99721 ttacaagatg gggccaaact agtctatgcc gtcgacgttg ggactaacca gttggtatgg
    99781 aaactcagac aagatccacg agtaagaagt atggaacagt ataactttcg ttatgctcag
    99841 ccagaggact ttaatgaggg acagcctgta tttgccagta ttgatgtgtc ctttatttct
    99901 ctcagcttga ttttgccagc cctgcataac gttttgtcag atcagggaca ggttattgct
    99961 ctcattaaac cgcaatttga agctgggcgc gagcagattg gtaaaaaagg catcgtcaaa
   100021 gacaaacaga ttcatgaaaa agtgattcaa aaggtcatgg attttgcctc agattacgga
   100081 tttacagtta agggacttga tttttcccct attcagggtg gtcatggcaa tatcgaattt
   100141 ttagctcatc ttgctaagtc acagacacct gaaacgttag ccccgcattt gattcagaaa
   100201 gttgttgcca aggcacataa ggagtttgag aaacatgaaa aagagtgaac gacttgaatt
   100261 aatcaaaaaa atggttttga cgcatccaat tgagacgcaa catgacctct taagattatt
   100321 ggcagagcat gggttagaat taacccaggc tactatttca agagacatga atgaaattgg
   100381 tatagtaaag attccttctg gcagtggacg ttacatctat ggtctttctc aagatagtgg
   100441 aaaaaagatc gttcaaggac ctagatcgat aaagagcact attttagctg tatctgacaa
   100501 aacaaaaggt ttagaacaac acctctattt aaaagtcgta cctggcaata gtaaattaat
   100561 caaacgttat ttattagcag atttttcaaa agctattttt agtcttattg ctgatgatga
   100621 tagtttattg ttaattgcaa ggtctccttc agaagcagat atgatacgcc aagaaatttt
   100681 gctttggatg cagggtataa cctagaaaaa aataggggag aaagtgatgt tattagaaat
   100741 ttctattaaa aattttgcta ttattgatga aatttcccta aattttgaaa atggtatgac
   100801 ggttttgacg ggtgaaactg gagcaggaaa gtctattatc attgatgcta tgaatatgat
   100861 gcttggtgcg cgtgctagta cagaagtgat tcgtcgtgga gctaataaag cagaaattga
   100921 ggggttcttt tcggtagatg ctaccccaga actggttgcg tgtctggaat catcaggcat
   100981 tgctatggaa gaagaactga ttattcgccg agatatcttt gccaatggca gaagcgtgag
   101041 ccgcattaat ggtcagatgg ttaacctagc caccttaaaa caggtcggac agtttttggt
   101101 agatattcat gggcaacatg accaagaaga attaatgcga ccacagctcc accagcaaat
   101161 tttggacgct tttggtgata aggcttttga gcaattgaaa gagaactatc agcttatttt
   101221 tgatcgttat aaaagcttgc gtcgccaggt tattgacaaa caaaaaaatg aaaaggaaca
   101281 caaagatcgt attgatatgt tggcctttca gatagcagag attgaagctg ctgccttgag
   101341 tcgaggtgag gacgaccggt taaatcaaga acgtgatcgc ttaatgaacc acaaacaaat
   101401 tgctgatacc ctgaccaatg cctacgtcat gctagataat gacgattttt caagtctatc
   101461 caatattcgc tctagcatga atgacttact atcaattgag cagtttgatt cagagtacaa
   101521 agggatgtcg acttcgattt ctgaagccta ttatattctt gaagaagtga gcaagcaatt
   101581 atcagatacc attgaccaac tggattttga tggtgggcga ttacaggaaa ttgaatttcg
   101641 cttggataca ctcaatagct taacccgtaa atacggtggt aatgtgaatg atgtgcttga
   101701 ctactacgat aatattatca aagaatacca gctattaaca ggagacgact tgtcttcagg
   101761 ggatctagaa tcagaattga aagccttaga aaaacaattg gttgctgcag ccactaactt
   101821 gagtgaatgc cgccatcaat tggcagagca attagaagct gagattaaag ctgaacttaa
   101881 ggaactttat atggaaaaag cagatttcaa agttcacttt accacatcaa aattcaatcg
   101941 tgatggtaat gaaagcttgg aattttacat ctctactaat ccaggcgaag gatttaagcc
   102001 ccttgtcaag gtggcttctg gaggagagtt atcacgcctt atgttagcca tcaaggctgc
   102061 tatttctaga aaagaagata agacgagtat tgtttttgat gaagtagata caggtgtttc
   102121 tggtcgcgtt gcgcaagcca ttgcccaaaa aatttataaa attgggcgac atgggcaagt
   102181 tctcgctatt tcacacttac ctcaagttat tgctattgct gattatcagt attttatttc
   102241 taaagaaagt aaagaagagt ccaccgtttc taaggtaagg ttattaactc ctgaagaacg
   102301 tgtggaagaa attgctagca tgattgcagg aacagatatg acacaagctg ctcttacgca
   102361 ggctcgtgaa ctacttgcca aacattaaga ttatgtttgg tatttgatat tttcataatt
   102421 agatgaaatt gattttttag gtgctaaaat aatcattgtg ctagaccatt tttcctctgt
   102481 taatctggct tggtttgcct tgacaaacct ctgagaaata gtagaataga taagagaatt
   102541 ttaagctgag gggatagaaa tgactagtaa aaaagcgtgt ttatcaagca tcattgtgtt
   102601 agcaagttta acgtgtggaa atgatactgt tagtgccaat catctctcag caactggaga
   102661 taagtttgat gattgctcaa cacttgttga aaaagatgtg gcccctaaag atgaacttga
   102721 gatgttagca tggtcctcgt ctcaaacaac tgatgatgct gacagagact atgaagattt
   102781 tctcgatgat gattctttta tttctcaaaa tgaaactgat aagatgtttg agaatttaac
   102841 tgatgatagg ttattaaatg aattagatga atcagatgaa gaagatgaag aagatacaat
   102901 tgagccagag caaaatgtaa taatgcctag tgacgatgag ctatttgatt taactgatgc
   102961 tgttgagaca cgccttactg tttctagtgc tccccattta gaggctgaat tgccgaaacc
   103021 acatttgagg agcctatcag atacagcact gcggtctggt gaaattagag gacatttaga
   103081 taacaaactg gacgctttgt ctgtaacagc tacaaagtta gcattaacga tggctcaaaa
   103141 atttgatttg acaacgcatg tctattctat aggtgaaagc tttagtgaag tattagctgc
   103201 tcattatgaa gatagaaaag cagaatcagc tttttctaag aaaaagagat ttcaccttcc
   103261 tattgctact ccagatgttg ttatagagga gttaaggcgc ctagtctctt ctattggaag
   103321 ttcaaaagaa gatgtttcag ttccttataa tcggaagcta ggtatggcag ttgcaaaaag
   103381 aaaaatagcc ttgccacaaa cgggagagga gttctcttat tatccagctt tacttggttt
   103441 aatgatatta ggattaacgc cgattatgat accaaagaag ataaataatt aggtaataag
   103501 ttattgtagt tgtaaaagac ggggcaaatg ttcaagcgtg aaaaggttga cttttgcctc
   103561 gttttgtatc tcgttattgc taaggcattt tcttcgagca gctagtgctc gccataccta
   103621 tctaccgagt gattattcaa tagcactacc agttttgctt tatttagtaa ggagtgttag
   103681 aataaagagg tgagaaacta gtttagaatg gaaaaataca tgggaactat aaaaattgtt
   103741 acagattcat caataactat tgaaccagaa ttaattaaag ctttagatat tactgtagtg
   103801 cctttatctg tcatgattga tagcaaatta tattctgata atgatttaaa agaagaaggt
   103861 cattttttga gtcttatgaa ggctagcaaa tcccttccca aaaccagtca gccaccggtt
   103921 ggtctctttg ctgaaactta cgaaaatttg gtcaaaaaag gagtaactga cattgttgct
   103981 attcacctct caccagcttt atcaggtact attgaagctt cccgtcaggg ggctgaaatc
   104041 gctgaggccc ctgttacagt tttagattca ggatttactg atcaagccat gaaatttcag
   104101 gtcgttgagg cagcaaagat ggcaaaagcg ggtgctagtt tgaatgagat tttggctgct
   104161 gttcaagcta tcaaatcaaa aacagagctc tacattggtg tatctacctt agaaaattta
   104221 gtaaaaggag gtcgtattgg tcgtgtgacg ggtgttttga gctcgctact taatgtcaaa
   104281 gttgttatgg cacttaaaaa tgatgagtta aaaacgcttg tcaaaggtcg aggtaataaa
   104341 acatttacga aatggttaga tagttacctc actaaaaata gtcatcgccc gattgcagag
   104401 atagctattt cttatgctgg tgaagctagc ctggcattaa cattaaaaga aagaatcgca
   104461 gcttattata atcattctat ttcggtttta gaaacaggct ctatcatcca aacacataca
   104521 ggagaaggag cttttgcggt tatggttcgt tatgaataat cgtcatttat ttagtgggat
   104581 atttttcttt gttattagtt tatgtctggc ctttttattg ctaaatatta ttatccctaa
   104641 gtcaaattca cgtttgaaaa agagtgattt tctgaaaaaa gaacaagtag ctatccaata
   104701 tgttgctata ggagattcat tgacagaagg agtaggtgat ctaactcatc aaggtggttt
   104761 tgttcctttg ttaacgaatg atcttagtga atattttaag gctaatgtta atcatcaaaa
   104821 ttacggcgta tctggtgata ccagtcaaca aattcttgat aggatgataa aacaaaagca
   104881 gatacagtta tctttaaaaa aagcagatat aatgacgtta accgttggtg gtaatgatgt
   104941 tatggcagtt attcggaaga atttagcgga tttgcaagtt tctagtttta gaaagccagc
   105001 tcgtcagtat caaaaacgat taagacagat tatcgagtta gccagaaaag ataataaaga
   105061 tcttcctatt tttattttag gcatctataa tccgttttat ttgaattttc cagaactaac
   105121 tgatatgcaa aaagtgattg atgactggaa taccaaaact aaggaggttg ttggagaata
   105181 cgatcgtgtg tactttgtgc caataaatga cctcttgtat aaagggataa atggacaaga
   105241 aggaattgtc cattcttcag gagatcaaac tacaattgtc aatgatgcct tgtttactgg
   105301 ggaccatttt cacccaaata atactggcta tcaaatcatg tcaaatgcag taatggagaa
   105361 aataaaaaag catgaaaaaa aaatcaaacg ttaattggtg gaagtggagc ttcttatgtc
   105421 tgcttgcttt taataccgcc tttttgatgg ttattgcaag tcgtctcatt caagtaagag
   105481 aacctgagtc agaactgatt gctaaaaaac cagttaaaaa tatcaaaatt ggtacatttg
   105541 tcacaaccag agaacagctt aacgaaactg tagcaagtta tcttaaagat tatcagacta
   105601 aaaaaatgtc ttataaattt tatgcgacat cttcttctat tttgtttgaa ggaacttatc
   105661 aattattagg gtatgaagtc cctttatata tctattttca acctcatcgt ctagaaaatg
   105721 gagctgtcca actacaggtg atctcttttt cagtgggaac tctgccactc ccagaaaaag
   105781 atgttttgca gtatttgaaa tcaagctaca aattgccaag ctttgttaaa gtgatgccaa
   105841 atcaatcagc tatcgttgtt aatttacaag atatccaaaa tgatgctaag gtttatttaa
   105901 aggccaagaa aattgattta tttaatgatg aaatcagttt taacatctat aagaaataac
   105961 ctcaaataac gttaaatact tgacctaatc gcttttttta gatatgataa tatctgttaa
   106021 agcattaagc ttactaatta tttggaggat ttgttaaatg gctaacaaac aagatttaat
   106081 cgcaaaggtt gcagaagcaa ctgaattgac taaaaaagat tcagcagcag cagttgatgc
   106141 cgtgttttct acaatcgaag ctttccttgc tgaaggtgaa aaagtacaat tgatcggttt
   106201 tggtaacttc gaagtacgcg aacgtgcagc tcgtaaaggt cgtaacccac aaactggtgc
   106261 agaaattgaa attgcagctt caaaagttcc agccttcaaa gctggtaaag ctcttaaaga
   106321 cgctgttaaa taattcgtct agaaaaatct tgttgctatc gatgtttatt gatagcgaca
   106381 aggttctttt ttatatttgg ggcatatttg gggcataaag ttagtagttt tctcttcagt
   106441 taagccaagt tctaatgcat gcactctata atggtcagtc atccttctat tagtatatca
   106501 tttccgcagg tagggggagt ttttttcata tttgcaaata gtcgaagtta ggatttttga
   106561 aagcaaaagg taagtttaaa aaagtttatt tagaatgctt ctaaattact tgacttattt
   106621 atttagaatt attataatta atgtatctta aagattgaat aacttttaat tgcgagggaa
   106681 ctaaaaatga caatcagaca atggatggca gaccatcttc atttaatgga gactttagcg
   106741 tgtttggtat taataataat tggcctagcc tttttacact catttccaca agtggcttcc
   106801 gctattttca ttacagcctt cttgattgga ggatatgcgt ctgcaaaaac gggtatattg
   106861 gatttggtga agaacaaaca cttgtcagtg gatattttga tgattttagc agctatcggt
   106921 gctggaatta tcggctattg gctggagggt gctctgctta tttttatctt ttcgttgtcc
   106981 aatacgcttg aagaaatggc catggaaaaa agtaaggatg ctatttcagc cttgatgtcc
   107041 ttgacgccag atacagctcg tcaataccaa gaagatggcc atattttaga agttgagacc
   107101 agatccttga gtgttggtga ccgtttacaa gttcgtaaag gcgaagctgt tccaattgac
   107161 gggcagttgc ttagtccttt tggtcaattt gatgaatcta tggtcactgg tgagcctatc
   107221 actgttgata aggcagaagg ccaggatctg attgggggaa ccattaacca aggacaaacc
   107281 atagatatgt tggttactat tgaaaatgac gatactctct ttgccaagat tattaatctg
   107341 gtggaatctg cccaagaaaa gaaaagcaaa actgccacct ttatcgaaag cttagaagat
   107401 ggttatgtca aatttgtgct cgtccttatt cctgccttta tcctctttag ccactttgtg
   107461 ctttcttgga cttggttggc tgctttttac cgagggatga ttctcttaac agtagcttca
   107521 ccatgtgccc taattgccag ttccacacct gctagcttgg ctgctatttc tcgtgcagcc
   107581 agaaaggggt tgattatcaa aggaggggat attgtcgata acatgggaga tattaaggct
   107641 gttgtcatgg ataaaacggg aacgctcacc caaggaaaac cttctgttgt gaatgctcat
   107701 tatttggaag atgagttgct cgtgaataga ctggtaaaag gagcagagac tgctagtacc
   107761 catcctattt ctaaagccct tcttgaatac actgaaaaat tggagccact gacctttgac
   107821 cacttagaag aaatttctgg gaaaggtttt cagggcttct atcaagggca agaatggcga
   107881 attggcaaga aaaccttcat tttggaaaag gttcaagacc tatcagcttt tgaagaaact
   107941 attcaagtgg aagaaaatca agggaaaacc ctaatctttg tttcacgtga ccatcaattg
   108001 atagcttact atgccctctt ggatgatatc aaaatagaat caaaacgtgc tattaagtct
   108061 cttcatgcca tgggaatcaa aacagtcatg ttaacaggtg accaagaacg aaccgccaat
   108121 tatgtggcac aaaaacttgg tattgatgaa gtggtagcca actgtatgcc tcaagataag
   108181 gtggctaagt tagcagaatt aaagaccaaa tatggttttg tggccatggt aggagatggt
   108241 attaatgatg ctcctgccct tgctcaagca gatgtttctt atgctattgg atcaggaaca
   108301 gatattgcaa tggaaagtgc agacagtgtg attatggatg acttgactcg tattccattt
   108361 tcgattcaac tttcccgcaa aatgaagacc attatcaaac aaaatattgt ttttgcctta
   108421 tctgtgatta ccttattgat tttagccaat gtttttcagg tagttaactt gccgcttggt
   108481 gttgttggac acgaaggctc aacgatttta gtgattttaa atggcttgcg tttactttct
   108541 tttaaataat ttagaaactt gcttgaaaac ttgaaagtgt ttataataat agtaagactt
   108601 atgaaagaga aaaccgccgt atgtttacta ttatgatcat tggtttagct gtattttcaa
   108661 taattaaaat cattctattt ttctattttt atcagcaatt tgagcgcaag caaaaaagaa
   108721 aagttgaatc aaacaaccag caaagacagt cccaagaaag tgacgctgtc ccttcaaaaa
   108781 aattcccatt ttaaaaagct tggaaagtgt acaaagtgca catttccaag cttttttgac
   108841 tattaaggtt aatctttgta acgtaagttc ccacgaaaat cgtctaagct ttgatagcct
   108901 ttttctacca taatcgtttt tagttcctta gtgacccgtt caaagatagc tggcccttct
   108961 tgatgaaggg ctgtcccaat ttggaccatg ctggcgccac aaagaatatg ttcaaaggca
   109021 tcgcgtcctg ttttaattcc ccctgtacca ataatgtgga tagaaggttt taagcgtttg
   109081 taaaacgcat ggacattggc tagagcagta ggtttgatgt aatctccacc tataccacca
   109141 aagccatttt taggcttgat gaggacttgt tcatcctcga tgaccagccc atttccgata
   109201 gaattgacac agttaacaaa ggaaaggggg tatttattga aaatcgcagc cgcttgatca
   109261 aaatgcacaa tgtcaaaata aggaggtaat ttgataccaa gaggtttagt gtaataggta
   109321 aagatgttct ctagaagttg atcagtggtt tcaaaatcat aagcaatctg tggttttcct
   109381 ggaatgttag ggcaagaaag gtttagttcc actagaccct cataatctga agccatgatg
   109441 gcttttaaaa tggtttcggt ttcagtagga gatagcccga caacggagag aaagtgaggt
   109501 ttatgttgcc cggttttggc aagatcactg acaaagtcta agtagtagcg aaaaccatta
   109561 ttagggagtc ccattgaatt gatagaacca agacgagtat ctgcgtagcg aggttctgga
   109621 ttacctggac gaacttcaag cgtccctgtt ttggtgacaa aggaagcggc ttgagacttt
   109681 tcaacctcca taagctcttc ttttgtcatg cagtaaacac cagcagcatt catcaaacag
   109741 ttatcaaaag agaaatgacc aatttgtgta gcagtagaaa ccattatttc ctccatattt
   109801 tagacaaatt ttttctattc taccactagg catgaataat agcaagctat ttttacaaaa
   109861 atgtaaatat attactgtta ttgacgaaca tttgaaattt tcatgatagt cacattatga
   109921 ttttcaataa agtcagaata gactagcttt tttgctatat tttttgtaaa ataggaattg
   109981 taaaaaggta gcaaccttta aattaaaagg agatattaac tcatggtaaa attggttttc
   110041 gctcgccacg gtgagtcaga atggaacaaa gctaacctct tcactggttg ggcagatgtt
   110101 gatctttcag aaaaagggac acaacaagcg attgatgcag gtaaattgat caaagaagca
   110161 ggtattgaat ttgaccttgc tttcacttca gtattgacac gtgctatcaa aacaactaac
   110221 cttgcccttg aaaatgcagg tcaattgtgg gttccaactg aaaaatcatg gcgcttgaac
   110281 gagcgtcact atggtgcttt gactggcaaa aacaaagctg aagctgcaga acaatttggt
   110341 gatgaacaag ttcatatctg gcgtcgttca tacgacgtgt tgccgccagc tatggctaaa
   110401 gatgatgagt attcagcaca caaagaccgt cgttatgctg atcttgaccc agctcttatt
   110461 ccagatgctg aaaacttaaa agtaactctt gaacgcgcaa tgccttactg ggaagaaaaa
   110521 attgctccag ctcttcttga tggtaaaaac gtctttgttg gcgcacatgg taactcaatc
   110581 cgcgctcttg tgaaacacat taaaggtctt tcagatgacg aaatcatgga tgtggaaatt
   110641 ccaaacttcc caccacttgt ttttgaatta gatgaaaaac ttaacattgt taaagaatac
   110701 taccttggtg gtgaataact taaaaaccag actttggtct ggttttttgg ttctatatcc
   110761 taagaagaaa gaaaaccctg cttaaaaata tgatatgata gaaataaaaa aggatagata
   110821 gattatgaaa gcagaagatc gtcgtcaaaa aattattgag tgcttaaata gtgaacaaaa
   110881 agctgtatct gctactcgtt taggtaagtt attaggagtg agtcgccaag taatcgttgg
   110941 agatatagct cttcttcgag ctcagcagat tgatattatt tcgactccaa aaggttatat
   111001 tatgtcaaca gcactttata gtcaccaatt ttgtgcacgt attgtgtgcc aacataatgt
   111061 agaagaaact aaaaaagaat tagaaattat tttagctcat caagggatta ttacgacggt
   111121 agaggtagaa catcctattt acggtatgat aacagcccct ttaaatatta agacacactc
   111181 tgatgtaact aatttcatgt ccaaactcag tcaatctaaa gcagagttat tgtcttcgtt
   111241 gacagaagga ctacatagtc acttaatttc gtgtcctagt caagaagcct ttttagctat
   111301 taagcatgat ttagaattag caggtatctt atacaaagga atataactat agtatattat
   111361 gccattgatg gttgttatga ataccatgct aaaatattct attgattatt tatcagcaac
   111421 aaggtatcgt ttaaaaatac caaaagatac aggtgtcttg atagttattg gtttttaagg
   111481 tatactattt ttgaaaagga gataaaatga ctaaaaaacc aacacaacta atagcttata
   111541 cctctatttt ggtcgcattt gcgattttga ttccgataat catgcctctt aagcttatta
   111601 ttggaccagc ttcctttact ctggcgagcc atgttccttt gtttttggct atttttatgt
   111661 cgattccagt agcaattttg gtcgctcttg gtaccacatt aggtttttta ttagctggac
   111721 tacctttaat tattgtttta agagcactct ctcatttatt gtttgctatt ttggcagcgt
   111781 ggtggttaag tagaaaacca caactgatga catcggcagt aaaatgtttt agttttgcgt
   111841 ttttcattaa tgtcattcat ggcttggctg aatttttagt tgtctatatt ttaacagcaa
   111901 ccacagcaac ttctatgtct tatttttggt ctatgctagg cttgattggc ttaggttcgc
   111961 ttattcatgg catattggat ttctatcttg ctttagttct atggcgtttt ttagcaaaaa
   112021 acttaaaact tcccaccata aatgcctaag actaaaatag agatagttat atgataatga
   112081 cgagcccttt cttgttgaaa gggcttgcat tttttaggaa aattgatata ctaaagtgtg
   112141 tgtttgtgaa tacagtaaca aaaggagata tcatgaaaac accagaacag attttagaag
   112201 caactattca tattggggaa cataaggtta ccaaaacttt tttggctaaa tctatcttag
   112261 gctttattgg tggagcgatg attagccttg gttatttact atacgtgaga attgccgcca
   112321 gtggtttaga aacttttggt gctttttcca gtatcgtagg agcttgtgct tttccgattg
   112381 gtctaattat tattttaatg gcgggtggag aattaattac agggaacatg atggctgttt
   112441 ctgcagcttt gttggccaaa aaaattaagt ttagcgagct tgccaagaat tggcttatca
   112501 ttaccttgtt taatgtgatt ggagctgttt ttgtagcttt tgtgtttggt cattttctag
   112561 gtttgacatc agctggtatt tttaaagagg aagtgattga ggtggcccat gctaaaatag
   112621 cagcgagccc tttgcaggca ctagtatcag gaattggttg taactggttt gttggtttgg
   112681 ccttgtggct atgctatggg gcaaatgatg ctgctggtaa attccttggt acttggtttc
   112741 ctgtcatgac ctttgtagcc cttggttttc agcatagtgt agcaaatgct tttgtcattc
   112801 ctgctgctat ttttgaagga ggagcaacat ggttggattt tgccactaat tttatttttg
   112861 tctatagtgg taatattatc ggtggagcca tttttgttag ttttttatat tttaaagttt
   112921 actatcatcc gcaaaagagt aaaactcaat gagaaaatat ttttttagac tgagggcgtc
   112981 ctattctcag tcttcttttt ataatttatg gtaaaataag aagcgaagtt taaaaaattt
   113041 agctaaataa tggttagttt attccctaaa aaaggagtat tcccaaaaaa tccgtaaaaa
   113101 gaatttgcta tgggagtagt tcccaaaata atgtagatca ttagttgtct ttcaaaaata
   113161 gccttgttag ggtaaaaagt ggacagtgat gcagcaacag attcatcagg cgtacaaact
   113221 gtcttatggt ttgtgcttgg agatttctta ataatgcttt tggtaataca cttttagtga
   113281 agaaagtgta gcatgaaagc ttaaagataa ccatgagttc gctttatgtg ctattgttga
   113341 gaaaaatagc atagtcaatt gagtaaacat catttctgca tggaatgaaa caattcctat
   113401 aaacttatat cataaggatg gtttgcgatt tctaaaaaag taacatgaat caaaaaacaa
   113461 aagccaaata tcccaaggcc aaggtaacaa gtcgagtaaa aaagttttta cttggctaat
   113521 ccaaacggtt ctgtcacgat tcacgctaaa attggaactg ctgagacttg tatcacagac
   113581 aattcagatc agaccttagt aacttacaac ttaaatgtag tagcttataa tacaaataac
   113641 gaagataata ttgcggttgc tgttatgtat ccacatatta cgaatatatc ggcaaagatg
   113701 tgagggcgct ttatgtggcg atatatggaa aacaataaag gagaacttag tgctttatcc
   113761 aacacccatt gcaaagttaa ttgacagtta ctctaaactt ccaggaattg gtatcaagac
   113821 ggcgacgaga ttagcctttt atactattgg aatgtcaaat gaagatgtca atgattttgc
   113881 taaaaactta ttagcagcta aaagagaact gacctattgt tcgatttgtg gaaaccttac
   113941 cgatgacgat ccttgtcaca tttgcacaga cacgagtcgt gatcagacga ccattctggt
   114001 agtagaagat gctaaagatg tttctgccat ggaaaaaatc caagagtatc atggctatta
   114061 tcacgtgctt cacggcttga tttcgcctat gaatggtgtg gggccagatg acatcaacct
   114121 taaaagttta attacccgtc taatggatgg taaggtgagc gaagttatcg tagctaccaa
   114181 tgccacagca gatggggaag caacgtccat gtatatttca cgtgtcttga aaccagccgg
   114241 gattaaggta actcgtttgg caagaggtct cgcagtaggt tcagatattg agtatgctga
   114301 tgaagtaaca ttattgagag ctattgagaa tcgtactgaa ctttaatgat catgttggtg
   114361 cctttactcg caaagagagg ttttgaaaag gctacatctt tttgttataa taaaaaaaca
   114421 ttcaattcag ataagaaagg ttagctatgt ccaaacaaac gttagttcta ttatacggag
   114481 gccgctcagc agaacgtgaa gtctcagtgc tttcagcaga gagtgtgatg cgagcagtca
   114541 actatgataa gttcttagta aaaacttatt ttattactca gatgggccaa tttatcaaaa
   114601 ctcagcaatt ttcagaaaag ccatcggaat cagaacgctt gatgacaaat gagacgatag
   114661 agctaactca aaaaataaaa ccaagtgata tctatgaaga aggtgcagtt gtatttcctg
   114721 tattacatgg acctatggga gaagatggct ctatccaagg tttcttagaa gtgcttagaa
   114781 tgccatatat agggactaat gtcatgtctt ctagcatagc tatggataaa attactacta
   114841 aacgtgtctt agaatcaatt ggaattccac aagttgccta tactgtttat attgacggac
   114901 aagatttgga ggcttgttta gttgaaactt tagcaagact tacttttcct atcttcgtaa
   114961 aaccagctaa tatgggttct tctgtgggga tttccaaagc ccaaacaaaa gtagaattaa
   115021 gaaaagcgat tcagttagcc ctgacctatg acagtcgtgt cttgattgaa caaggcgtgg
   115081 ttgccagaga aattgaagtt ggtctccttg gaaatgataa ggttaaatca actctaccag
   115141 gagaagtaat caaggacgtt gatttttacg actaccaagc aaaatatgtt gataataaga
   115201 ttacgatggc cattccagca gatgtagatc agagtattgt gacagaaatg cgttcttatg
   115261 ctgaagtagc ctttaaagcc ttaggtggtt gtgggttgtc ccgttgtgac tttttcttga
   115321 cccaagacgg acaggtttac cttaacgaat taaacaccat gccaggcttt acccaatggt
   115381 ctatgtatcc actcttatgg gaaaatatgg gattggctta tccagatttg attgaagagc
   115441 tggtgacact ggcacaagaa atatttgatc agcgtgagag ccatctgatt taaacctatg
   115501 agatgaataa acattgactt ggatggaacg gcaaacatcg tcaagatgtg acgttcgtcc
   115561 tttttttgtt gctcttttag gaagaatagt agagccatta agggagtttg acattttaga
   115621 aatttttcta atgttttgtg ctataataga taggacatcg taaatactag tgttcttaga
   115681 aagaaaacaa aatgaaatta accttacacg aagtggctaa aatagttgac gcccaaaata
   115741 atgtgtctga cttagacgac gttcctctgc atcacattga atttgatagc cgaaagatta
   115801 caaaaggaga cctcttttta cccttaaaag gtcaaaggga tggtcatgag tttattgatt
   115861 tagcctttca aaatggagct gtcgctactt tttcagaaaa agaattgtcg gggaaacctc
   115921 accttcttgt tgaagactgc ctaaaagctt ttcaaaagct agcccattat tatattgata
   115981 agatgcgcgt ggatgttatt gctgtgacag gctcaaatgg taaaacttcc accaaagata
   116041 tgataggagc tgtcctatca accacttaca aaacttacaa aacgcaagga aattacaata
   116101 atgagattgg tttgccttac accgttctcc acatgcctga cgatacggaa aaaattgttc
   116161 ttgaaatggg acaagatcac atgggagata ttcgtcttct gtctgaaatt gcaaggcctc
   116221 gtattgcagt tttaacctta gtcggcgaag ctcatttaga atattttgga agccgaaaca
   116281 aaatagccca aggcaaaatg cagattgttg acggcatgaa ttcagatggg attttaattg
   116341 ctccgggaga tccgattatt gacccatatc ttccagaaaa tcagatggtt atccgttttg
   116401 gaaatcagca ggaaattgac gttactggta ttcaagaaga caaagatagc ttaacgttta
   116461 caacaaatgt gttagcaaca cctgtgtccc tacctctacc aggaaaatac aacgcgacca
   116521 atgctatggt agcagcctat gtaggaaaac tattggcagt aacagacgag gatattatag
   116581 ctgctttaca gactgtgacg ttgacaggta atcgtacgga gtggaaaaaa gcagccaatg
   116641 gtgctgatat tttatcagat gtctacaatg ctaacccaac agccatgcgt ctgattttag
   116701 aaacatttgc taacatagca aagaaccccg gaggaaaaaa gattgcagtg ctagcagata
   116761 tgaaagaact tggaaaggat tcagtgatac ttcattctca gttaattgac agcttaacat
   116821 caggtaatat tgatcagctt gttttttatg gggatcatat taaagaatta gcacggttgg
   116881 caagtcaggt ttatcctgct gagcaagtac attatttttt aaaaactgaa caagaagacc
   116941 agtttgaagc catggcacaa tatgttcaaa acattcttaa tccctttgat caaattcttt
   117001 taaaaggcag ccactcgatg tcgcttgaaa agttagtgga ccgattagtg actgacaaga
   117061 attgtgacag ctatcagcct tgatttttat aaaactttca gagaaaggct tgttctctca
   117121 tgaagattaa ggtataatga aaaaatatag aaagggacga ttatggattt ttttgcaatt
   117181 gaccccatcg gactgcctca tacctcactt atcttttact tgtcgtcact cttgatagcg
   117241 cttttgcttg tttttttgac ttttcaagca tataggttaa aatcttatcg ttattttttc
   117301 ttgtttttac agttatctca ggtgattggc ttgtacacat ggtacgtgtt aagggggttt
   117361 cctttagatg aagctttgcc gttgtatcat tgtcgcatcg ctatgttagc tatctttttt
   117421 ctacctgatc gtaacaagtt taagcaatta tttatggttt tggggatagg tggaacattc
   117481 cttgcacttt tatcgccaga tctttatccg tttagattat ggcatgtagc aaatgtctcg
   117541 ttttatcttg gtcattatgc tttgttagtg aatggtttga tttacctctt gcgtttttac
   117601 gatgccagtc agttaagact gctatcagta gtacgctatt tagcaactgt taactttctt
   117661 cttctgttgg tcagtttagc cacgaaagga aattatggtt ttgtgatgga tattccagtg
   117721 attcatacgc gtcatttgct acttaatttt gtgatcgtta caagtggctt gacttttatg
   117781 gttaaaataa ccgaatattt ttaccttaaa tttggtgaag ctcaacagct ggcatttgct
   117841 ttttctaaag aaaagtaggt cgttgaaaaa gcacttaaaa tcagctataa taagaagagt
   117901 ctgggatgat ttccaggctc gattttttta aaaaagacac tcattgatag cccaagataa
   117961 gttataatac cagttttgaa gaactttaga ggctaatcgt atatggagaa acccaatgta
   118021 gcccaactct tttgataaac aagtaatacc taacgaaaat aactcagaga aaagctctgc
   118081 cattttacta tacaaggaaa aaagaatgtc acttacagaa gaaattaaaa aacgccgtac
   118141 ttttgccatc atttctcacc cggatgctgg taagacgact attactgagc aactattata
   118201 ttttggtggt gaaattagag aagcagggac agtaaaaggg aaaaaatcag gtacgtttgc
   118261 aaagtccgac tggatggata ttgaaaagca acgtggtatc tctgttactt catctgttat
   118321 gcaatttgat tacgcgggta aacgtgttaa tattttggat acacctggac atgaggattt
   118381 ctcggaagat acataccgga ccttaatggc tgtggatgcg gctgtcatgg ttgtagattc
   118441 ggctaaaggt attgaggcgc aaacgaaaaa actttttgaa gttgtcaaac atcgtaatat
   118501 tcctgtcttc acctttatta acaagttaga ccgtgatggg cgtgagcctt tagaactctt
   118561 ggaagaatta gaagaagttt tagggattgc ttcttatccg atgaactggc cgattggtat
   118621 gggacgcgcc tttgagggct tatatgattt acataataaa cgtttagaac tctataaggg
   118681 agacgagcgt tttgcaagta ttgaagacgg tgatcagctg tttgccaata atccctttta
   118741 tgaacaagtc aaagaagata ttgaacttct tcaagaagca ggtaatgact tttcagaaca
   118801 agctattctt gatggtgacc taactccagt cttttttggc tctgccctta cgaactttgg
   118861 agttcagact tttcttgata ctttcttgga gtttgcccca gaacctcatg gtcacaagac
   118921 tacagaaggt aatgttgttg accccttagc taaagatttt tcaggttttg tctttaaaat
   118981 tcaagctaac atggacccta aacaccgtga ccgtattgct tttgtgcgta ttgtttctgg
   119041 tgaatttgag cgcggtatgg gagttaattt gacacgcact ggcaaaggcg ctaagctctc
   119101 caatgttact caatttatgg cagaatcacg ggaaaatgtg acgaatgctg ttgctgggga
   119161 tattatcggg gtttatgata caggaactta tcaagttggg gataccttaa cagttgggaa
   119221 aaataaattt gaatttgaac ccttaccaac ttttacccca gaaatcttca tgaaggtttc
   119281 tccgaaaaat gttatgaagc agaaatcctt ccacaaaggt attgaacaat tagtacaaga
   119341 aggagcaatt cagctttata agaattatca gacaggcgaa tacatgctgg gtgctgtggg
   119401 tcaactgcag tttgaagtct ttaaacatcg tatggaaggt gaatacaacg ctgaagttgt
   119461 gatgacacca atgggtaaaa agactgttcg ctggatttca gaagatgatt tggatcaacg
   119521 catgtcctca agccgaaaca ttttagctaa ggatcgtttt gaccaaccag ttttcctatt
   119581 tgaaaatgat tttgcccttc gctggtttgc agacaaatac ccagatgtca ctttagaaga
   119641 gaaaatgtaa tcgaaacatg attttcaaca gtctaacgtt ttggagatca atttactgag
   119701 caacttttta aaagaaatga gtggctagtt atctcttttg cagatttaag attctatcaa
   119761 aaaacgatat cttcacaact gtaagcatat ttatgattta gcggataatc gtgaaagcgt
   119821 gttattgctt atattagcct tatttcctat ctttttgatt ctaattgtgt tacactagtt
   119881 aggttgttaa tcaaacgacg aaaattaaaa ggtttataag gcagcttcgc actgcctttt
   119941 tagaaaagag aaacaattga aatttacaga atttaactta tcacaagaca tccaatcagc
   120001 tgttgttacc gctggttttg agaaagcatc tcctatccag gaaatgacga ttcctctcgc
   120061 actagaaggg aaggatgtta ttggtcaagc acaaacagga actggtaaaa cagcagcgtt
   120121 tggtctacca accttgaata agattcgtac taacgaaaat atcatccaag cattggtcat
   120181 tgcaccaacg cgtgaattgg ctgtacaaag tcaggaagaa ttgttccgtt ttggacgtga
   120241 aaaaggggtt aaggttcgct ctgtttacgg tggatcaagt attgaaaaac aaatcaaagc
   120301 ccttaaatca ggtgcccaca ttgtcgtggg aacaccaggc cgcttgttag atttgattaa
   120361 gcgcaaggct cttattttag atcatgtgga aaccttaatc cttgatgaag cagatgaaat
   120421 gcttaacatg ggcttcttgg aagacattga agctattatc agtcgtgtcc cagcagaccg
   120481 tcagaccttg ctcttctccg caacgatgcc ggcacctatt aaacaaatcg gggttaaatt
   120541 catgaaagac cctgaacatg ttcaaattaa gaacaaagaa ttaacaaacg tcaatgttga
   120601 tcaatactat gttcgtgtga aagaacaaga aaaatttgac actatgaccc gtctgatgga
   120661 tgttaaccag ccagaattat ccatcgtttt tgggcggact aagcgccgag ttgatgaaat
   120721 tacacgtggc ttgaaacttc gtggtttccg tgccgaagga atccatggtg atcttgacca
   120781 aaataaacgc ttacgtgtta tccgtgattt caaaaacgac caaattgata ttcttgttgc
   120841 cactgatgta gcagcgcgtg gccttgatat ttcaggagtt acccacgttt ataactacga
   120901 tattacccaa gatccagaaa gttatgttca ccgtattggt cgtacaggtc gtgccggtaa
   120961 atctggtgag tctatcactt ttgtctcacc aaatgagatg ggctacctct caatgattga
   121021 gaacttaacg aaaaaacaga tgaaacctct tcgcccagca actgctgaag aggcctttca
   121081 agccaagaaa aaagtagccc tcaagaaaat tgaacgcgac tttgcggatg agactattcg
   121141 ttcaaacttt gataaattca aaggcgatgc tgtccaattg gctgccgaat tcactcctga
   121201 agaattagct ttatatattt tgagcttaac agttcaagat ccagatagct taccggaagt
   121261 tgaaattgca cgtgaaaaac cattaccatt caaatatgtg ggtggtggtc acggcaataa
   121321 aaatggcaaa ggtggtcgtg gacgtgacaa ccgtaaccgt ggtgatcgcc gtggcggcta
   121381 tcgtggtgac cgtaacagag atgagcgtga tggtgaccgt cgtcgtcaaa aacgtgataa
   121441 gcgtgatggt cacgatggca gtggcaaccg cgatttcaaa cgtaaatcaa aacgtaatag
   121501 taaagacttt ttcaataaag agaaaaaatc aagtgctaaa aatactggtt ttgtgattcg
   121561 tcacaaaggt gaataagctt aaagagagtt gatgagagtc agctcttttt aattttctga
   121621 aaaagttgct tttataatgg aatctgttat aatggtttca gttattttgt tataattttt
   121681 aaaaaattag gaggagtata agatgtctga tagccatctt actgcctttg acaaagcttc
   121741 aaaagcaggt tttattattg ctttaggtat tgtttatgga gatattggaa caagccccct
   121801 ttatacgatg cagtctctag ttgaaaatca aggaggggtt aatcaggttt ctgaatcctt
   121861 tattttagga tcaatctctt taattatttg gacactgacc ttgatcacaa caatcaagta
   121921 cgttttgatt gctctaaaag ctgataacca ccatgaaggt gggatttttt ctttattcac
   121981 cttggtacgt aaaatatcac cgtggctcat tattccggcg atgattggag gtgcaacact
   122041 tttgtctgat ggggctctta cacctgcggt aacagttact tcagctattg agggcttgaa
   122101 agccgttcct ggtctgagtc acatctacca aaatcaaacc aatgtcatta tcacaactct
   122161 agtgatttta atagtcttgt ttggtattca gcggtttgga acaggtttta ttggtaaaat
   122221 ttttggacca gttatgttta tctggtttag ttttctaggt gttagtggtt tttttaatac
   122281 gttggggcat ctggaaattt tcaaggctat caatccttac tatgctctgc atttgctgtt
   122341 tagtcctgaa aaccatcgtg ggatttttat cttggggtcc atttttcttg cgacaacagg
   122401 agctgaagcc ctttattcgg atttaggaca tgttggtcga ggaaatattt atgtgagctg
   122461 gccctttgtt aagatgtgta ttgtgttgtc ttactgtggc caggctgcgt ggattttagc
   122521 gaataaacac tcaggtattg aactaaaccc tttctttgct agtgtgccat cacaattaag
   122581 ggtttacctt gttagtttgg caaccttagc agccattatt gcctcacagg ctcttatttc
   122641 aggctccttt accttggttt cagaagccat gcgtttgaaa attttccctt tgtttcgtgt
   122701 gacttaccca ggggcaaatt tggggcaatt gtatattcct gtcattaact ggattttatt
   122761 tgcagtgacc tcttgtactg ttttggcttt tagaacatca gcccacatgg aggcagctta
   122821 tggtcttgct attaccatca ccatgttgat gacaacaatc ctcttaaagt attacttaat
   122881 caagaaagga acgagaccca tcttggctca tttagtgatg gctttctttg cccttgtaga
   122941 attcattttc ttcttggctt cagctatcaa atttatgcac ggtggctatg cggttgttat
   123001 cttggcactt gcaattgtct ttgtcatgtt tatctggcat gcgggcacac ggattgtttt
   123061 caagtatgtg aaatctctta atttgaatga ttacaaggag cagattaaac aacttcgtga
   123121 cgacgtttgt tttgacctct accaaacaaa tgttgtctac ctatccaatc gtatgcagga
   123181 tcatatgatt gaccggtcta ttttatactc cattttagac aagcggccaa aacgcgctca
   123241 agtttattgg tttgtaaatg tccaggtaac tgatgaacct tatacagcta agtacaaggt
   123301 agatatgatg ggaacggatt atatggttcg agtcaacctt tatcttggtt ttagaatgcc
   123361 acagactgtg ccacgctatt tgcgcacgat tgttcaggat ttgatggaaa gtggccgttt
   123421 acccaaacaa gaacaggaat ataccatcac acctggtcgt gatgttggtg attttcgctt
   123481 tgttttaata gaagaacggg tctccaatgc acgtcaattg agtaactttg aacgctttat
   123541 tatgcacact aaggcaagca ttaaacatgt taccgctagt ccaatgcgtt ggtttgggct
   123601 tcaatattca gaagtaactc ttgaagtggt tcccttgatt ctatcagata tcttgaagtt
   123661 accaatcaaa gaattgatgc ctgtggaaga cagtgaagca taaaaaaatc attgagatga
   123721 taagtctcaa tgatttttct tttctttttg atgagtagca atataggcca atttctggct
   123781 tcttgttttt cgttttttaa agagtgcttc agcgctcatc gcagcctttt tgctatcaaa
   123841 cacttcgtaa taaagtaaag aaacaggtaa ccggtagcga gtatatttag ccccctttcc
   123901 tgcgttatgt gtagctaagc gttttttcaa atcagttgta taaccagtgt agagggtttt
   123961 atctgcacat tctaacacat acatataagc ttttttagtg gtcatgatta ggttttcctt
   124021 tggaagcagc accaaaataa atctcaaaaa tatgatcagt gtattctccg ttttccttgt
   124081 ggacaactaa aggaggtaaa atagtcatcc cttcaataga accgtctttg attgcttcaa
   124141 taagtaacat attagctgat ttacctaatt taggatagac aaattgtacc cttttagggg
   124201 caagaccatt agctctaagg ctatctataa tttccaagaa tcgatctggt cgatgaacca
   124261 ttgccagacg accatttgat ttaagggcat gacgggctac ctgacaaatc tcttctaaat
   124321 tagtggtcac ttcatgacga gccagtaaat aatgttcaga gacgttcttc ttagaacttt
   124381 cgtgactttt aaagtaaggg ggattgcaga gcatcaaatc aactcctgaa cgtggcacat
   124441 ggtttaggag gttttttaaa tcatcacaaa tcatggttac ttggtcttcc agttgattga
   124501 gctggataga gcgttgtccc atatcagcaa gccgtttttg taattctact tcaacgatgg
   124561 ctgccttggt tctagtgcta gcaaataagc caaccgcccc atttcctgag cacaaatcca
   124621 caattaaccc tttggaaggc atcttgggga agcgggataa gaggacgcta tcaatagagt
   124681 aactaaagac atccttgttt tgaataatgc caacatcact tgaaaagagt tgatcaatac
   124741 gttcgccttc ttttaagatt gcttttatca tacctgttat tttaacataa aataggcttt
   124801 aggtgaatgt ttgaagagtg attttgactt tcgaaaagtc aactttcatg atacaataag
   124861 taagattatt ctattaaagg agaagcctgt gttttacgct tacttacgcg gtttagtagt
   124921 ctttttatta tgggttgtca atggcaatgc ccactaccat catgaagaaa agatgttaga
   124981 tgcttctgag aattatattc tggtagcacc ccatcgaacc ttttgggatc cagtttacat
   125041 ggcatttgca gcacgtccta agcagtttat ttttatggct aaaaaagagt tgtttgcaaa
   125101 tcgtctcttt gcttggtgga ttaaaatgtg tggtgctttt cctattgatc gtgataaacc
   125161 gagtccagat gctattcgtt accctgttaa tatgctcaaa aagagcaatc gttctcttct
   125221 tatgtttcca agtggaagta ggcattcgca agaggtcaaa ggaggggtcg ctgtgattgc
   125281 taaaatggct aaggtcaaga ttatgccagc agcctatcag gggcctatgt cggttaaggg
   125341 attactagcg ggagaacggg ttgacatgac ttttgggaat cccattgacg tctcagatat
   125401 taaacgcatg aatgatgaag ggattgctga ggtggcaaac cgtattcagg cagagtttga
   125461 tcggatggat gacgagttgg cacctttcca accaggcaaa gcaaggaacc ctttaactta
   125521 tctctaccgt ttaccattag gattggtttt ggtggtggta ttattattaa ccatgttatt
   125581 ttcctatatt gctagttttg tttggaatcc agataaacat cgccattaag aacatgaggg
   125641 ctaacatgtg cctgaaataa gaagtgattg agattagtct tctattgaaa gaagccgcta
   125701 atgcttaatc acttttttca tttctaaaaa agatattcga tgataccctt aactctttta
   125761 agcacaaaaa atgacaatac tactatactt ttggatatca tttacgaata aaaagatgag
   125821 gtaaaaaaat gttagacgaa ttattaatta aaggaaaatc gtttttgaga gagcggtatt
   125881 ttctgccata cctaattagt cttttattag gactttttct aatactaagc ttcagttttt
   125941 tgttctgggg aaataggcag agcaaggcag ccgttcctgc tttgagagaa atatcgcctg
   126001 tgaaacagca ggttagtgaa gaaaaaaaga aaattcaaga agatagcagt attttagtgg
   126061 atttaaaagg cgccgtacaa aaagagggag tttataagct aactgctagc agtcgtgtgc
   126121 gagatgtcat tgaactagct ggaggcctaa cttcagaagc tgataaacat gctattaatt
   126181 ttgcagaaaa actaactgat gagcaagttg tttatgtacc taaacaagaa gaagagattt
   126241 ctgtgctacc aagatcatta gtttctggta aaaaagaaac tgccagcaag gatcagtcaa
   126301 aggttcatat taataaggcc agcttagaag aactacagca tatcccaggt attggtgcta
   126361 aaagagctca ggatattatt gatatgagag ataagttagg tggttttaaa gcgttagaag
   126421 atctccgtca ggtttcgggg attggcgaaa aaacgctcga gaaattaaaa gatgacattt
   126481 tcttggacta agctagtgcc cctgtcaaag attcaatttg cttttttaat cttggttctc
   126541 ttttatcaaa tccatagccc tagctggtta acgtttctcc ttagccttag tttgatttgc
   126601 ttacttgtca agcgtttgtc taaaaaagaa ttcctcggtg tctttgccat ccttagtttc
   126661 tgtgctttgt ttttgctgta tcagaaacag cagttggttc aaaaactgga aattcagcca
   126721 gtacaaataa cctctgtagc attagttcct gatagtattc ggattaatgg tgatcaatta
   126781 gctgttcttg gatgtcatgg gaaacattct tatcagttat tttaccgttt gaaaagccaa
   126841 gcagaagccc aattgttcaa gaaagagcac cgttggttag tgatacacgc aaaagtgaca
   126901 ttggaaaaag ctgaggaagt tcgaaatttt aaaggcttta attatcagac ttttttggct
   126961 tatcaaggaa tttacaggat agggaaggta gagcaaatag aacagcttga agtgatttca
   127021 cccgagtcaa tatgtgacta tttgtcctct ttaagacggc gagccattgt tcattgccag
   127081 cagcattttc caagacctat gtctcactac ctgacgggcc tcctttttgg ttatttagat
   127141 aagtcgtttg gtgagatgac agattattat agtcagttgg gtatcattca tctctttgct
   127201 ttatcaggga tgcaggttgg cttctttctt acttgtttta gaagggtgtt gctattactc
   127261 gcagttcctt tggaatggat aaaatggata gagcttcctt ttgcttgctt ttatgccgcg
   127321 ttgacaggtt atagtatttc tgttattcga agcctcgtgc agtcgcagtt gcgtcattta
   127381 ggaataaaag gattagacaa tctggcttgt acttttttac ttgtcttttt atgggatgct
   127441 catttcttaa tgactgttgg tggcgtatta acgtttagct atgctttttt gttaacagtg
   127501 gttactgttg aagaattatc aggagctaaa agacagttgg tacaagtctt gaccatttcc
   127561 ctaggaatat taccattttt gctcttttat ttttctagtt ttaacccaat gtcaatggtc
   127621 ttaacagggc tcttgtctta tctctttgac ctttttattt tgccccttct ttgtctggtt
   127681 ttttgtctat cccctttggt gactgtctca atatgtaacc atctttttat tttattagaa
   127741 aaagtcattc aatttctcgg aaatactttc aatagttccc ttgtttttgg aagcccgacc
   127801 agttggcact tgcttatctt ggtgattagc ttcgctattt tttatgatta tcggcaggtg
   127861 cgacaacgag ttatcacttg cggtttggtt atagcgttga cgcttttgtc tgtcaaatat
   127921 cctttgacca atgaagtgac ctttatcgac attggccagg gagatagtat tttggtgagg
   127981 gagtggacag ggaaaaatct cttaatagat gtaggtgggc tccctttctt ttcttcaaaa
   128041 gagcactggc gacgaggaca tcacgtagct aatgctcaga aaaccttaat tccttactta
   128101 aaaagtagag gtattcacac aattgaccaa ctattagtaa ctcacgcaga tactgatcat
   128161 atgggggata tcgaagtggt tgccaaagct attcggataa aggagatttt gactagtcaa
   128221 ggcagtttaa gccatccaag ctttgttagg cggctaaggc gtttaaaatg tcacgttagg
   128281 gttttagcag ctggagacca gttgcctatt atgggaagtg tcttacaggt actctaccct
   128341 tggcagttag gggacgggaa aaataacgat tctttggtac tttatggcag gctcttaaat
   128401 cgaacttttc ttttcacagg tgacttggaa aaagaggggg aaaacgagat cataaaacgt
   128461 tatcctcagc taagagtaga ttatttaaaa gcaggtcacc atggatcaaa tacctcttct
   128521 agtgcagctt ttttagacca tattcagcct aaagtggcct ttatttctgc tggaaaaaat
   128581 aaccgttatc agcatcctca cagagaaacc ttagcccgtt tggaagacag acaaattact
   128641 tattaccgaa cggatacgca aggagctatt cgtttgactg gttggacaag ctggcatctt
   128701 gaaacggtcc gttagttaaa attccagcct gacgaagaaa caggcagtcg ctttcctttt
   128761 aggagaaaga tgatataata aaagcatgat tgcgatagaa aagattgaaa aactgagtaa
   128821 agaaaatttg ggtcttataa cccttgtcac aggagatgac attggtcagt atagccagtt
   128881 gaaatcccgc ttaatggggc agattgcttt tgataaggat gatttggcct attcttactt
   128941 tgatatgtct gaggccgctt atcaggatgc agaaatggat ctagtgagcc tacccttctt
   129001 tgctgagcag aaggtggtca tttttgacca tttgttagat atcacgacca ataaaaaaag
   129061 tttcttaaaa gaaaaagacc taaaggcctt tgaagcctat ttagaaaatc ccttagagac
   129121 tactcgacta attatctttg ctccaggtaa attggatagt aagagacggc ttgttaagct
   129181 tttgaaacgt gatgcccttg ttttagaagc caaccctctg aaagaagcag agctaagaac
   129241 ttattttcaa aaatacagtc atcaactggg tttgggattt gagagtggtg cttttgaaca
   129301 actgctttta aaatcaaacg atgattttag tcaaatcatg aaaaacatgg cttttttaaa
   129361 agcctataaa aaaacgggaa atattagcct aactgatatt gagcaagcca ttcctaaaag
   129421 tttacaagat aatatttttg acttaaccag acttgtccta ggaggtaaac ttgatgtggc
   129481 tagagatttg attcatgatt tacgcttatc aggggaagat gatattaaat taattgctat
   129541 tatgttgggg caatttcgct tatatttaca gcttgccatt cttgctaaag aaggaaaatc
   129601 agaacagcag cttgtaacca gtttgtcaga gatacttggt cggcgggtta atccttacca
   129661 ggtcaagtat gcgttaaagg attctaggac cttatctctt gcctttctaa caggagcggt
   129721 gaaaaccttg attgagacag attaccagat aaaaacagga ctttatgaga agagttatct
   129781 agttgatatt gctctcttaa aaatcatgac tcactctcaa aaataggcgt tggaccgctt
   129841 tccaagagat aatcaaatta gttgaaagct cttatttttt gcgataagat agacgtatca
   129901 taaaggaaaa gaggacagga aaatggctat tattttacca gaacttccat acgcgtatga
   129961 tgctcttgaa ccacagtttg atgcggagac aatgactctt catcatgata aacaccatgc
   130021 cacttatgtc gctaatacca atgcggcttt agaaaaacac ccagagatcg gagaaaatct
   130081 ggaggaacta ttggcagatg tcactaagat tccagaagat attcgtcaag ccttaattaa
   130141 taatggtggc ggacacctaa accatgcgct tttctgggaa ctattatcac ctgaaaaaca
   130201 agacgtcact cctgatgttg cacaagccat tgatgatgct tttgggtcat ttgacgcctt
   130261 taaagaacaa tttacagcag ctgctactgg acgttttggt tcaggttggg catggttagt
   130321 tgttaataaa gaaggacaac tcgaaatcac atcaaccgct aaccaagata ctccaatttc
   130381 agaaggcaaa aaaccaattc tagcgcttga tgtgtgggag catgcttact acttgaatta
   130441 tcgtaatgta cgtccaaatt atatcaaagc tttctttgaa atcgttaatt ggaaaaaagt
   130501 atcagaactt taccaagccg ctaaataaga aaagggtttc caatctcaaa aagagattgg
   130561 ttttttaagt gcttttttga ataacagtgt ggggacatca ttttttagaa aagataaaaa
   130621 tagtttgtct ttttaatgca attccttgat ttttagctaa atttagctag aatagaatgg
   130681 ataggagatt ttaggtgtta agagagaaga aaactaccat tgtagggatt attttaggaa
   130741 tgatgatagt gaccttactt gtcggctgtt tgactggtaa aaagaaaggc tttcctccta
   130801 aagcaggtga gcggcagcaa acggctgact taaaaatgaa aaaaagatta gaaaactgtt
   130861 caaaaaccgt tacctgaaaa atctaaagag gctaagcaag ctgttatgga tgcagattta
   130921 gcgcaaatgg atgtcttagg gctctattac gatgacaacc atttgagttt ggtcaatacg
   130981 gtcaaggcgt atttaaagga atttggcatt ggtgaatccc aaattgcctt ttcctacaaa
   131041 gacctcaatt caggcaggac tgctgccatg aatgaccatc agccaatgat tgcaggaagc
   131101 acctataagc tgccattaaa catgctggtg gtagataagg caaattatcc atgacagagc
   131161 gttttgacat tacagaaact gattatgaat atgatcagga acatcatgcc tatgttgctc
   131221 agttcaatgg tgccatgtct attccggata tgcaagatac tcagaaatca cgccagctta
   131281 tgctctagca gaacgattgg gtggcatgaa taaggcttac caattatttg accgctacgg
   131341 gaaggtatcc ggggctatta cgaccactga tcgtaatggc aataaaatca ccaccgctta
   131401 ctatttgcaa gttttggatt acttgtggca gcatcaggat aaatataagg atatcttgta
   131461 ctacattggt gaatctttcc ctgatttgta ttacaagact tatttgcctc atgtaaaggt
   131521 ttatcaaaaa ccgggttatg tcagagaagc cttaaatgta ggtgccattg tttgcgaaga
   131581 gtctccttat ttgattgctc tttattcatc tggtttgggt ggagcaacac aagcatcaga
   131641 ggaagtcaat ggccttggtt atgtgcagct tgttcagcta ccatatgtaa ttaatgagtg
   131701 gcatagagtc aatcacaaca tgatctaata ctcagttgac attagtctga tagtagacat
   131761 acttactgat gaaagtcact aaaataagtt tttgctcatt aaaaaagctt ggcctgtttc
   131821 ttcaggtcaa gctttttgag attaatgctg tgtttttgag gtcttattgt cacctcttgt
   131881 ttcttgataa tggtgaagca attttttgaa ttttttaacg gcagcgcgtg ttagctgctt
   131941 agatgatttg ccatttctgc tgtaaatggg attgtgctta tccctttgct gttctaaatc
   132001 gggaactaga aaagttgcat caggactatt aattgctttt tcaataaaag ccggatcaaa
   132061 aagcagaata gggtcaatat caagcagacg gtgcaagtca tcgttttggt tgccataatt
   132121 gaaagaagaa ccattgacaa tactatttcg cgttaggtta tcaggatcta gtgctactaa
   132181 aaattgtcca gattctgaca aaataaactc tgagtgaaaa tgaattaaaa tcttatagtt
   132241 ggcttgagga atattgtctg tatagactgc ctgatgattg ccattagcat ctaaaatact
   132301 agcaacctta ttatggtatc tagaagattc ataaagagca taatcgtcat cttctagagt
   132361 agccaaatat ttggctaagg catccgcatc ggttttccct ttattcccat aatgtgagcg
   132421 aacccactcc gtttgctggg ttgatatgag gtaacggagt tgatgaattt tccgattaaa
   132481 acggctataa ggaatgtgtt cgagattaac ataacaagcc tgaatcaagg cagataattg
   132541 gtcccaaaaa ggatctgttg gcgatagctt tggacttaat tgtgccaata cttgctgtgt
   132601 ttgttttgat tgtcctgtca actcgtctgg catctttaaa tacgtcaaga gcagctgtag
   132661 ccgtttttga gcttcttgag gcgtctgtgc catctcttct tgttgccaga gcttttgaaa
   132721 gtcaggtgat cctatcaggc gaatgcgact ataaagttgt tcgaaatgat aagagtttcc
   132781 tctaacagcg agttgttcaa ggtatccttt ttggatggct ttataggacc atccgtcctt
   132841 atcgagtttt cgaacataat caagcaagtc gtggcgtaat ttaatagctt ctgaaagctg
   132901 gagttctcgt aatttaggat agttttggta aaaaggcgcc actaagtcct gataagattt
   132961 gtgttctttt tcaaaggcaa tccgctgata gtctttctgc caaaaactga cgcaaaaagt
   133021 cagaaacatc aagaagaata gccattttcc aagtaatttc ataggttttt agttgacaaa
   133081 catggcatcg ccaaagctaa agaaacgata tttttcgtca accgcgtgtc tgtaagcttc
   133141 aaggacaaag tcacgctctg caaaggctga tactagcatc acaagggttg attttggaag
   133201 atggaaatta gttgaaaaag catcaactac cttgaattgg tagcctggtt taataaaaat
   133261 attggtccaa cctgaatcag cttgaatgtc cccttggaac ttacttccga tggtttccaa
   133321 cgtacgaata gaggtggttc ctacagcgac aacacgaccg ccagcttgtt tgacgtctct
   133381 tagggtttgc gctgcttctt ctgagaggga ataaaattcc gaatgcatat catgctcatc
   133441 gaggttatcc acggaaacag gtctaaaagt cccaagccct acatgtaggg tcaaataaac
   133501 caaatgtacc cctttggctt cgattttttt gagcaagtct gttgtgaagt ggagaccagc
   133561 agttggggcg gccgcagagc cattttcttt agcataaacg gtttggtatc gctcagcatc
   133621 ctctaatttt tcgtgaatat aaggaggcaa tggcatttcg ccgaggctct ctaaaacttc
   133681 taagaaaatc ccatcatagc tgaattcaac aattcgtcca ccatgttcta attcgtcgat
   133741 aatggtggct ttgagatgcc catctccaaa attgacttgg ctaccaacct tgagccgttt
   133801 ggctggcttg gctaaaactt cccattgatc tccttgtgta tttttaagca aaagcaattc
   133861 cacatgacca tgagtatcgg gtttttctcc ataaagtctg gcaggcaaga cacgggtgtt
   133921 attcatgacg agggcatccc ctggatttaa ttgatcaatg atatggtcaa aatggctatc
   133981 aaccatagtt ttttgacggt gatcaataat caatagtttt gaactgtctc ttttttcgag
   134041 tggggtttgg gcaatcaatt cttctggtaa ctcaaaatca aaatcgttag tattcattgg
   134101 ggctccttta aagccactag taaatctctt cctagtaact ctttcatgta agataaatct
   134161 tttctattat atcacttgtc gtctaacccg tcatctttaa tctttcatca gaaagtaaag
   134221 gataggcttg acaaaaattg gtatatacca tataataaaa acacgaaagg tctataccaa
   134281 ttagaaaagg agaatgacat gaaaattatt cgggtccaag atcagattga aggtgggaaa
   134341 atcgctttta ccttattgaa agatagctta gctaagggag ctaagacgtt aggattagca
   134401 acaggaagtt caccaattag tttttaccaa gaaatggtca aaagtccttt ggatttttcg
   134461 gacttaacaa gtattaactt ggatgaatat gtcggtcttt cagtagagag cgatcagagt
   134521 tatgattatt ttatgcgtca aaaccttttt aatgcgaagc cttttaaaaa gaattacttg
   134581 cccaatggtt tagcaaccga tgtcgaagca gaagctaaac gatatgacca aatcattgca
   134641 gagcatccga ttgattttca agtgcttggg attgggcgta atgggcacat tggttttaac
   134701 gaacctggga cctcttttga agaagaaacg catgtggtgg atcttcaaga atcaaccatt
   134761 gaagccaata gtcgtttctt tacaagtatt gaggatgtgc caaaacaagc tatctctatg
   134821 ggaattgcct ccatcatgaa gtccaaaatg attgttcttc ttgcctttgg acaagaaaaa
   134881 gctgatacga tcaagggaat ggtttttgga ccaatcacag aagacctccc agcaagtatt
   134941 ctccaaaaac atgatcatgt tatcgtcatt gtggatgaag ctgctgcgtc acaattagac
   135001 taacctaacc agtcgttaaa ccttgtaaga acaaaaatga ggagatagtc aacctcattt
   135061 aagaagaagt cttgtaactt ctatttcttt tgcaagggta aatttatgtt acactactaa
   135121 tatgcgttta gataaattat tagaaggtac aaaagttggc tctagaagtc aagtgaagaa
   135181 actgattaag gctcaagggg tttgggttga tcacatgcct gccagaaatg gtcgacaaaa
   135241 tgttgatcct ggcttacaac tgattgaggt gactggacag cgagtgacgc atcctaaaca
   135301 ttcttacatt atcctcaaca agccatcagg ggtggtctca gctaagaaag atactaacta
   135361 tttaaccgtt attgatcagc ttgctgaaga agataaaagt ccagacttgt atcctgttgg
   135421 cagattggat agagataccg aagggttggt tttactcact gataatggtc ccctagggtt
   135481 tcggatgttg caccctagtc atcatgtttc taaaacgtat cttgtaaccg ttaatggctt
   135541 gttagcagaa gatgcctcag atttttttgc agctggtatt tgtttcccaa caggtgaaca
   135601 atgccaacca gctcaattga ctattcttaa agccgataca gaccagtcac aggctagttt
   135661 gaccatttca gaaggaaaat ttcaccaagt gaaaaaaatg tttttgacct atggtttgaa
   135721 agtgacctct ctgaaacgga cgcactttgc agggctggaa ctcggtcatt tagccagcgg
   135781 agaatatcgt tatctaacag cgtcagaaag gcaactcatt aaaacgtatc tggactgagc
   135841 aaaacatgct ttcaaaaaga agctattctt gcttaatcaa taaagtgtcc attgactatt
   135901 atagtcatga tgagtccgac ttttgctatg tttagtcatc ttgttgttac aaaatcagat
   135961 aagcaaaaag attcaattcc cactatctcc ttaacctgaa gcgttataaa aacccttgtg
   136021 ttaaactctc ataaaattgg aaatgggagt gttttttgat ggctaaaaaa ctaaagctac
   136081 ttaaagtttg gtacttagtt ttcgaataat aaggtggaag atctaatagg aggtgacaaa
   136141 aatattaacc gctttagatg gtaagaatca gctcatttcg ctagtaactc agcctatttc
   136201 aacgaaaccg ccttttcgtt gcccagcttg caaatctcct gttcgcttgc gtcaggggac
   136261 aattagacga cctcattttg cccatgtaca actagctcat tgtcaattcc aagcagaaaa
   136321 tgaatctgag gaacatttga cgttgaaggc aaaactttac accagtttag tccgaacaga
   136381 agctgtctgt attgaaaaat atcttcctga gctgcaacag atagcagacc tttgggtgaa
   136441 tgataagtta gccttagaaa ttcagtgcag tcccttgcca gttgagcgtc taaagaaacg
   136501 caccaaagcc tatcaagaaa aggggtatcc ggtacgatgg ttactgggaa gaaaattgtg
   136561 gcttaacact cacttaactg ctttgcaaaa acagtttctt tacttttcat ctagtttggg
   136621 ctttcatttg tgggagctgg atgcagctgc aaatctgcta cgtctcaaat atttaatcca
   136681 tgaagactta tttggtaagg taagttacct aaccaaaacc atttctttag accacaatat
   136741 tatggaaatg tttcgattac cctatcagca agaaatcctt tattcttatc agaaaaaaat
   136801 gactgtgaac ctatctaaaa gaatacaaag agctctttta gctagacacc cgaaatggct
   136861 acgacgacaa gaaaaggctt acttatcagg ctataattta cttatgttaa caactgatgc
   136921 tttttatcct caatggagac cagttcaatc ttccagcggt ttttgtcaaa ttaaaggaaa
   136981 tcttcgccct tattatgaaa gttttaaagt ctattataaa aaagaaaagg ataagaaggt
   137041 gcaaacgctt ttttcaccaa aatattatgt taaaatggat agtaatagaa aatgagaagg
   137101 agatgttatg actgataatc gcagccattt agaagaaaaa tacacttggg atttgagcac
   137161 tatttttgca acagataagg attgggaagc tgaagtcagt gacttagcta ctgaaattga
   137221 cgcggctaag gatttttcag gtcatttact agattctagc gctaatctgt tgacaattac
   137281 agatacttat ttagagttag ctcgtcgtgt tgagaaagtc tatgtttatg ctcacatgaa
   137341 aaatgaccaa gacactactg ttgccaagta tcaagaatac caagctaagg cttcaggctt
   137401 gtatgcaaag tttagcgaag tgttttcatt ctatgaccca gaagttatgg cattgagtca
   137461 ggaagattac caagcttttc ttgcggaaac acctgattta aaaaggtatc atcatttctt
   137521 tgacaaattg ttccagacac gtgaccatgt gctcagccag gctgaagagg aattattagc
   137581 aggagcccaa gaaattttca acggcgctga agaaaccttt agtattcttg ataacgctga
   137641 tattgtcttt ccagtagtta aaaatgataa gggggaagat gttgaattaa cccatggtaa
   137701 cttcattagc ctaatggaat ctaaggaccg tagcattcgc caagctgctt atgaagccat
   137761 atatagtact tatgaacagt tccaacatac ttacgctaaa accttgcaaa ccaatgtgaa
   137821 agtgcaaaac tataaggcgc gtgttcataa atacgattca gcacgtcaag ctgccatggc
   137881 tgctaacttt attccagaag ctgtttacga taccttgtta gaaacggtta ataaacattt
   137941 gccactctta caccgttatt tgaaattgcg tcaagaagtt cttggtttag acgatttgaa
   138001 gatgtatgat gtttacacac cattatctga aacagatcta gccattggtt atgatgaggc
   138061 tttggaaaag gctgagaagg ttttggctgt ttttggtaaa gattacgcag atcgtgtgca
   138121 tcgtgctttt accgaacgtt ggattgatgt tcatgtcaat aaagggaagc gctctggggc
   138181 ttattcaggt ggttcctatg ataccaatgc cttcatgctg ttgaactggc aagatacact
   138241 tgataatctt tacacacttg tccacgaaac aggccacagt ttgcattcta ctttcactcg
   138301 tgaaacacag ccttatgtgt atggggatta tagtatcttc ttggcagaaa ttgcatccac
   138361 aacgaatgaa aatattatga cagaagctct cttaaatgaa gtgcaagatg agaaagaacg
   138421 ctttgccatt ttaaaccatt acctcgatgg tttccgtgga acagttttcc gtcaaaccca
   138481 atttgctgag tttgaacatg ccattcatca agctgatcaa aaaggagaag tgttaacaag
   138541 tgaatacctt aaccagctat acgctgattt aaatgaaaaa tattatggtt taagtaaaaa
   138601 agataatcat tttattcagt atgaatgggc acgtattcct catttctatt acaattatta
   138661 tgtttaccaa tatgcaacag gttttgcagc tgcaagctat ttagcggata agattgtgca
   138721 tggcacacaa gatgatatcg atcattactt ggcctacctc aagtcaggaa attctgatta
   138781 cccacttgaa gtgattgcta aagcaggcgt tgatatggca aaaggtgatt atttggaagc
   138841 cgcctttaaa gtctttgacg aacgtctaac agaacttgaa gtactcgtgt ccaaaggcat
   138901 acacaaaagc taaaatcaca aaagtcaagg acaaaaagag tttaggattg atagaaatgg
   138961 agattcacag ttggtgtgaa tctccatttc tatcggtcat tttcttttta tattttagtg
   139021 gattatcagt cctgaaaagc aggcttcatt gaccttagtt tgacggtttc ttttttgtct
   139081 tttttattgt gtggtcactc acttaaataa aatcaatagt tgagtaaggc gcttcagatt
   139141 aacgctattc tattgtttta gagataacgt tcgcataaaa catattttta ttatatttga
   139201 cattttataa aagagataat agaattaaaa tactaacatt tatgtttttt taaaaataaa
   139261 cgttcgtata ataaaaaagg agtttttcat ggaaaaaaca aaacgttata tcattgcaac
   139321 agcagggata cttctccact taatgttggg atcgacctat gcttggagtg tttatcgtaa
   139381 tccaatttta gaagagaccg gttgggacca agctcctgtc gcttttgcct tttctttagc
   139441 tattttttgt ttaggtttat ctgctgcttt tatgggaaat ttagttgaac aatatggtcc
   139501 tcgtctaacc ggaacggtgt cagctattct ttatgcttct ggaaatatgc tgactggttt
   139561 agcgattgat cgtaaagaaa tttggctttt atatattggt tatggtgtta ttggtggctt
   139621 aggacttgga gcgggatata tcacaccgat atcaactatt ataaaatggt ttccagataa
   139681 aagaggcatg gcaacagggt ttgctattat ggggtttggt tttgcgtctt tattaacaag
   139741 tccgattgcc cagtggctaa ttgaaacaga aggtttggta gcaacatttt accttttagg
   139801 gctgatttat ctaatagtta tgctttttgc ttctcaattg ataataaaac caactgctgc
   139861 tgagatagct atactagata aaaaaagatt acaaaataac agttatttaa tcgaaggaat
   139921 gaccgctaaa gaagcactta aaacaaaatc attttattgt ctttgggtaa ttttatttat
   139981 caatatcaca tgtggcttag gacttatctc agttgttgcg ccaatggcac aagatctaac
   140041 tggtatgagt ccagaaatgt cagcaattgt ggttggtgct atggggattt ttaacggttt
   140101 cggtcgttta gtgtgggcta gtttgtcaga ctacattgga cgccgtgtga cagtaatact
   140161 tttattttta gtaagcataa ttatgactat tagtttaata tttgcacata gttccctaat
   140221 tttcatgata agcattgcca cccttatgac ttgttatggt gcgggttttt ctctcattcc
   140281 gccttattta agtgatcttt ttggggcaaa ggaactggct acattacatg ggtatatatt
   140341 gacagcttgg gcaatagctg cattaactgg acctatgtta ttatctatca ctgttgaatg
   140401 gactcataat tatcttctta ccttatgtgt ttttattgtc ttatacattt taggattaat
   140461 ggtagcatta aggttaaaga aatgatgtcc tataaaaaat ttaaaagtaa accctagcaa
   140521 agcctagggt ttttttatat aattaggttt atggttaaat catacagtaa aacagcaaat
   140581 cataatatgc gtcgtcctgt tgtcaaagaa gagcttgttc attatatgcg aacacggcag
   140641 aagcaaacca caggtttttt agcagagtta gagcaattcg caagacaaga aaacattcct
   140701 attattcagc ctgaggtcgt ggcttatttc aggtttttat tgcaaagctt acagccaaaa
   140761 cacattttgg agattggcac agccattggt ttttctgcgc ttttaatggc tgaaaatgca
   140821 ccagatgcga cgattgtgac tattgatcgt aatcgagaga tgatcgattt tgctaaagca
   140881 aattttgcta agtacgacag tcgccaacag atccgcctgt tagaaggaga tgcagcagat
   140941 atattatcta cacttgaagg aaattttgac tttgtgttta tggattccgc caaatccaaa
   141001 tatattgtct ttctaccaga gattttaaga ctgctaaaag tcggtggtgt agtcattttg
   141061 gatgatgtct ttcaaggagg tgatattaca aaaccgatcg aagacattcg acgaggtcag
   141121 cgtactattt atcgtggctt acagtctttg tttgatgcca ccttaactca tccaaaccta
   141181 acaactagcc tggtccctct tagtgatgga ttattaatga ttcgtaaaaa tcaagcagat
   141241 attgtattac cagattaagt aacattgata aatttatgtt ataataaatt agttaaagat
   141301 aaaaaggagc tcagaagtaa atgaaaaact caaataaact cattgctagt gttgtgacat
   141361 tggcctcagt gatggcttta gcagcttgtc aatcaactaa tgacaatact aaggttattt
   141421 cgatgaaagg tgatacaatt agcgttagtg atttttacaa tgaaacaaaa aacacagaag
   141481 tatcgcaaaa agcgatgcta aatctggtaa ttagtcgtgt ttttgaagct caatatggtg
   141541 ataaggtttc aaaaaaagaa gttgaaaagg catatcataa aacagctgaa cagtatggcg
   141601 cttcattctc tgctgctttg gcacaatcaa gcttgacacc tgagactttt aagcgtcaga
   141661 tccgctcttc aaaattagta gaatatgcgg ttaaagaagc agctaaaaaa gaattgacaa
   141721 cacaagaata taagaaagca tatgaatctt atactccaac aatggcagtc gaaatgatta
   141781 ctttagataa tgaagagaca gctaaatcag tcttagagga actaaaagtc gaaggcgcag
   141841 actttacagc tattgctaaa gaaaaaacaa caacacctga gaaaaaagtg acctataaat
   141901 ttgattcagg cgcgacaaat gtaccgactg atgtcgtaaa agcggcttca agtttgaatg
   141961 agggtggcat atcagacgtt atctcggttt tagatccaac ttcttatcaa aagaagtttt
   142021 acattgttaa ggtgactaaa aaagcagaaa aaaaatcaga ttggcaagaa tataagaaac
   142081 gtttgaaagc tatcattata gctgaaaaat caaaagatat gaatttccaa aacaaggtta
   142141 ttgcaaatgc attggataaa gctaatgtaa aaattaaaga caaagctttt gctaatattc
   142201 tagcgcaata tgcaaatctt ggtcaaaaaa ctaaagctgc aagtgaaagt tcaacaacca
   142261 gcgaatcatc aaaagctgca gaagagaacc catcagaatc agagccaaca cagacatcat
   142321 cagctgaaga accaactgag actgaggctc agacgcaaga gccagctgca caataagtag
   142381 gattttattg actaatcagt taaaaaaact tataataatt tagttaagaa ttgtttatca
   142441 aggattagat acagaaaagt gacggttgct gcgagtcatt gataattaga taaacatgct
   142501 acttaacttt acaacaattg atatcgtaaa ttaagaatga caagttcatt gaatagaggt
   142561 ggtaccgcgg ttttcgccct ctgtgagatg gacttgtttt gtattgagga ctatttgaaa
   142621 tcaacgaaag gaatagagta gactaggctg ccaggcttat agctgatctc ctagcaagaa
   142681 agacgagctg tgtcaactgg tgtgattaca ttactagctt cagcataaca ctgtttttct
   142741 tactctttgt atctaaattt ttatgaaaga attatcgtct gcacaaatcc gccaaatgtg
   142801 gttggatttc tggaaatcta aaggacattg cgttgagcct tcagctaact tggttcctgt
   142861 gaatgaccca acgcttcttt ggatcaactc aggtgttgca accttgaaaa aatactttga
   142921 tggttcagtg attccagaaa atccacgtat taccaatgca caaaaatcaa ttcgtactaa
   142981 tgatattgaa aatgttggta aaacagcacg tcaccatact atgtttgaaa tgcttggtaa
   143041 cttctcaatt ggagactatt tccgtgatga agctattgag tggggatttg aactcttgac
   143101 aagtccagac tggtttgatt tccctaaaga taagctctac atgacttatt acccagatga
   143161 caaggattca tataaccgtt ggattgcttg tggcgttgaa ccaagtcact tggtgccgat
   143221 cgaggataac ttctgggaaa tcggtgctgg tccttcaggt ccagatacgg agattttctt
   143281 cgatcgtggt gaagatttcg atccagaaaa tatcggactt cgcctcttgg ctgaagatat
   143341 cgaaaacgat cgttacatcg aaatctggaa catcgttctc tcacaattca atgctgaccc
   143401 agccgtacca cgttcagaat acaaagaatt accaaacaaa aacattgata caggtgctgg
   143461 tcttgaacgt cttgcagctg ttatgcaagg ggcaaaaaca aactttgaaa ctgacctttt
   143521 catgccaatc atccgtgaag tagagaagtt gtcaggtaaa acttataatc cagatggcga
   143581 caacatgagt ttcaaggtta tcgctgacca catccgtgcg ctttcatttg ctatcggtga
   143641 tggtgcgctt cctggaaatg aaggtcgtgg ttacgttctt cgtcgtcttc ttcgtcgtgc
   143701 ggttatgcac ggtcgccgtc ttggcatcaa cgaaactttc ctttacaaat tggttccgac
   143761 tgttggacaa atcatggaaa gctactaccc agaagtgctt gaaaaacgtg attttatcga
   143821 gaaaatcgtt aaacgtgagg aagaaacatt tgctcgtact atcgatgcag gtagcggtca
   143881 cttggattca ttgcttacgc agcttaaagc tgaaggtaaa gatacacttg aaggtaaaga
   143941 tatcttcaaa ctttatgata cttatggatt cccggttgaa ttgacagagg aattggcaga
   144001 agatgcaggc tacaagattg accacgaagg ctttaagtca gccatgaaag aacaacaaga
   144061 ccgtgcgcgt gcggctgttg ttaagggtgg ctcaatgggg atgcaaaatg aaaccctagc
   144121 tggtatcgtt gaaaaatcac gcttcgaata cgacacatat agtcttgaat caagtctttc
   144181 agttatcatt gctgataatg aacgtactga ggctgtttca gaaggccaag cccttcttgt
   144241 ctttgctcaa acaccattct atgctgaaat gggtggacag gttgctgacc acggtgtcat
   144301 caaaaatgat aagggtgaca cagttgctga ggttgttgat gttcaaaaag caccaaatgg
   144361 tcaacctcta cacactgtaa acgttttggc atcactttca gttggaacaa actacacact
   144421 tgaaatcaac aaagagcgtc gtttggctgt tgagaaaaac cacacagcta ctcacttgct
   144481 ccatgcagct cttcacaatg ttatcggtga acatgcaact caggctggtt cattgaacga
   144541 agaagaattc ttgcgctttg attttactca ctttgaagca gtaagcaatg aggaacttcg
   144601 tcacattgaa caagaagtta atgagcaaat ttggaacgct cttacaatca caacgactga
   144661 aactgacgtt gaaaccgcaa aagagatggg agcaatggca ctttttggtg agaaatatgg
   144721 taaagtggtt cgtgtggttc aaattggtaa ttattctgtt gaactttgtg gtggaactca
   144781 cttaaataat tcttcagaaa tcggtctctt caagattgtc aaagaagaag gtattggttc
   144841 aggcactcgt cgtattattg cagttactgg tagacaagct tttgaagctt atcgtaacca
   144901 agaggatgcc ctaaaagaga tcgctgctac tgtaaaagct ccgcaattga aagatgcagc
   144961 agctaaagta caagctctta gcgactcact tcgtgatctt caaaaagaaa atgcagaact
   145021 taaagaaaaa gcagcagctg cagcagctgg tgatgtcttt aaagatgttc aagaagctaa
   145081 gggcgtgcgc ttcattgcta gtcaagttga tgttgcagat gcaggggcac ttcgtacatt
   145141 tgctgataac tggaaacaaa aagactactc tgatgtgctt gttctcgtag cagctattgg
   145201 tgagaaggtt aatgtccttg ttgcaagcaa aaccaaagat gtccacgctg gtaacatgat
   145261 caaagaattg gcaccaattg tagcaggtcg tggtggaggt aaaccagaca tggctatggc
   145321 aggtggtagc gatgcaagta aaattgcaga gctgctagca gcagttgctg aaacagtgta
   145381 aacccataaa aaaccaagtt atttagaact tggtttttta tatttgaaat gactattatc
   145441 ataacctttt tgactattat cgttatcaaa aagaaaaaga tatgttacaa tgatagtaac
   145501 aaatagacat gaggaggtgt tagagaaaat gacacatggt atcaaactta agaggcagat
   145561 ttgcttatgg gcaagtatcc tgactctttt cattttaagt tatcatctta tcagggtaat
   145621 ctggtttgga gtacccttga gttatctggt tttgggcttt acaggactag ccttgctgtt
   145681 gaatactttt tcttatttta gaaagtaagt tataagttaa agaagaatga aggagatggc
   145741 aatggaggtt attcttaaaa atcggctcaa agaattacga gccagagatg gaattaatca
   145801 aacggaaatg gctaaactgg caggagtatc gaggcagacc atcagtctca ttgagcgtaa
   145861 cgagtacacc ccatcagtta taattgccat gaaaattgca aaggtatttc aggaaccagt
   145921 tgaagaggtg tttcgtctag tggaggtcga ggaatgaaaa agaagaagaa tagtttttta
   145981 cgcttgttaa aaatgttatt gctatcaagt ttggcgggag ggattatagg tggcatggtt
   146041 ggagcctttt taggttacca tggagagaga ttagatcagc tcacgttcct aaaagatgat
   146101 gtgattaacc tgattatctt attaaatcgt ctggtagttg tcacaggcct cacactttct
   146161 tttgtttttt taacgcaact gaaaaaagag acagctgttt ataacacaat tgaagaggat
   146221 gattattctg aaaatggtta ccgtcagctg aataaaaagc atgcttatac catgttattg
   146281 attgccgtag cttctatttt atccatgtgc aatgtgctac ttggtctgac cttaactaat
   146341 gattcacagc atgccatgct ggccattccg cttctggata tccttttatt attaatggtc
   146401 attccttttc aagctttagc catgaaacgt tacaatgcca ttcggggaac cgatgttcct
   146461 tattttccaa atttgaaaga attaaaacat aatatcatgg ctctagatga ggcagagtta
   146521 caagcctatc ataagacatc gtttgaaagt gtgttgtcat taaatggagt catcatccct
   146581 tccttgtatg tgattttatt ttttgtctat ctattcactg gtcaagtgga gttaacagcc
   146641 atcttagttt tggtgttaat tcagctctat ttactcgtta agagtgcaac aatgaccaga
   146701 caattttacc gttagcctaa aaggagactg tttatgaaag gattcattaa ttatttaaaa
   146761 atagcagtgc tcattattct ggctatggtt ttcaatgtcc ttccgatgat tttattgcaa
   146821 aagcaacacg atattcctat ggtgcttaat tggggaattg gtattttcta cttggttatt
   146881 gttggaagtg tccttattgt attatggcgt ctttatcaag ctaagcaaga cacccctatt
   146941 aaacagcaaa aaatgagatt ggttgactgg ggttatttag cattattttg gttaatcatc
   147001 cgtgtgatag ctattgtagg tacccttgtt aaccagctat ggtctggtca acaagtgagt
   147061 gctaatgatg ctgcaataca taccttagct agacttatca aaggtggttt cccgctttat
   147121 actgccctat ttgtacttgt gatagctttt atcgctccta ttatggaaga actagtcttt
   147181 agaggatttc ctatgattga tctcttcaaa ggaaaatcac ttaaggtggc aggtttagtg
   147241 acctctcttg tttttgcttt accacatgcc accaatagtg ttgaatttat catgtacagc
   147301 tgtatgggca tttttctctt tgttgcctat caaagacgag gaaacttaaa agacgctatc
   147361 ttgttacata tttttaataa cttgattgaa gtcattttgt taatgtcaat aggcttagga
   147421 gtcatataat aaaaagcttc ggatgaatga actgcacccc aaaagttgga caaaaaaatc
   147481 taacatttgg ttggacttgt caagaaaaat agacataaaa ttaagctaat gagtaactat
   147541 tttttcaaat tcaacaggtg agagataccc taaagctgaa ggcagacgtt tagggttata
   147601 gtaagtctca ctatatttaa aaatctcaag ctgagcttgc t
//
LOCUS       DATTYN010000002       128641 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.02, whole genome shotgun sequence.
ACCESSION   DATTYN010000002 DATTYN010000000
VERSION     DATTYN010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 128641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128641
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.02"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            644..1904
                     /locus_tag="VB649_000135"
                     /pseudo
     CDS             644..1904
                     /locus_tag="VB649_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692285.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2146..2673
                     /locus_tag="VB649_000136"
     CDS             2146..2673
                     /locus_tag="VB649_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEP1669122.1"
                     /translation="MSIDDYRPTYMVEAIYDLRANDLLRHGITAVLVDLDNTLIAWNN
                     PDGTPEVRAWLDEMTIADISVVVVSNNKHSRVERAVSRFGVDFISRALKPFAYGIEKA
                     IARYGFDRNEVIMVGDQLMTDIRASHRAGIKSVLVKPLVASDAWNTKINRWRERRVMA
                     KLEEKYGKLSYQKGI"
     gene            2673..3791
                     /gene="yqeH"
                     /locus_tag="VB649_000137"
     CDS             2673..3791
                     /gene="yqeH"
                     /locus_tag="VB649_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEP1669123.1"
                     /translation="MEELFCIGCGIQIQTEDKEKAGFTPAAALKKGMETGELYCQRCF
                     RLRHYNEITDVHITDDEFLRLLHEVGDSDALVVNVIDIFDFNGSIIPGLSRFISGNDV
                     LLVGNKKDILPKSVKDGKVTQWLTERAHEEGLRPLDVMLTSAQNKYAIKDLIERINEL
                     RNGRDVYVVGVTNVGKSTLINAIIQEITGNKDVITTSRFPGTTLDKIEIPLDDGTFIF
                     DTPGIIHRHQMAHYLSPKELKIVSPKKEIKPKTYQLNPEQTLFLGGLSRFDFINGERQ
                     GFTAFFDNQLELHRTKLAGADAFYDKHVGTLLTPPGKKELTAFPKLVRHEFTIDQKMD
                     IVFSGLGWIRVNGQKDSKAIVAAWAPEGVAVIVRKAII"
     gene            3816..4124
                     /gene="yhbY"
                     /locus_tag="VB649_000138"
     CDS             3816..4124
                     /gene="yhbY"
                     /locus_tag="VB649_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEP1669124.1"
                     /translation="MLTSKQRAFLKSEAHSLKPIVQIGKNGLNDHIKTSIRQALDARE
                     LIKVTLLQNTDEDIHEVAEILEEEIGCDTVLKIGRILILYKVSAKKENRKLSPKVKAI
                     "
     gene            4193..4825
                     /locus_tag="VB649_000139"
     CDS             4193..4825
                     /locus_tag="VB649_000139"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEP1669125.1"
                     /translation="MALELLTPFTKVELEEEKKESNRKQIGILGGNFNPIHNAHLVVA
                     DQVRQQLGLDQVLLMPECKPPHVDAKETIDEKHRLCMLELAIEDVEGLAIETCELERQ
                     GISYTYDTMLYLTEQHPDVDYYFIIGADMVDYLPKWHRIDELVKLVQFVGVQRPKYKA
                     GTSYPVIWVDLPLMDISSSMIRDFIKKGRQPNYLLPKQVLDYITQEGLYQ"
     gene            4822..5415
                     /gene="yqeK"
                     /locus_tag="VB649_000140"
     CDS             4822..5415
                     /gene="yqeK"
                     /locus_tag="VB649_000140"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEP1669126.1"
                     /translation="MTYEDYLPYSRTELLAKIAEQMSPKRFKHVLGVEKAALSLAECY
                     GCNSDKAGLAALLHDYAKECPDQVFLDLIDKYQLSPELAKWNNNVWHGMVGIYKIQED
                     LGLKDKDILRAIKIHTVGAAEMTLLDKVLYVADYIEEGRIFPLVDDARKIAKLDLNQA
                     VAYETVNTVAYLASKAQPIFPQTLDTYNAFCSYLKEY"
     gene            5439..5792
                     /gene="rsfS"
                     /locus_tag="VB649_000141"
     CDS             5439..5792
                     /gene="rsfS"
                     /locus_tag="VB649_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEP1669127.1"
                     /translation="MKKEELLKIVVEATDEKRAKDILALDLEGLTSLTDYFVIASATN
                     SRQLEAIADNIREKVKEAGGDASHVEGNSQAGWVLLDLTDVVVHLFLEDERYHYNLEK
                     LWHEAPAVALDAYLA"
     gene            5840..6583
                     /locus_tag="VB649_000142"
     CDS             5840..6583
                     /locus_tag="VB649_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP1669128.1"
                     /translation="MEHNYEKFASVYDAVMDDSLYDLWTDFSLRHLPKSKGRNRLLEL
                     ACGTGIQSVRFAQAGFDVTGLDLSQNMLAIAKKRAQSAKKKIDFIQGNMLDLSQVGQF
                     DFVTCYSDSICYMQDEVDVGDVFKEVYDVLANDGIFIFDVHSTYQTDECFPGYSYHEN
                     ADDFAMVWDTYADEAPHSVVHELTFFIQEDDGRFSRFDEVHEERTYELLTYDILLEQA
                     GFKSFKVYADFEDKEPTKTSKRWFFVAQK"
     gene            6658..7755
                     /locus_tag="VB649_000143"
     CDS             6658..7755
                     /locus_tag="VB649_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEP1669129.1"
                     /translation="MTVTGIIAEFNPFHNGHKYLLEQAQGLTVVAMSGNFMQRGEPAL
                     VDKWTRAQMALANGADLVVELPFLVSVQSADYFAQGAVAILEKLGIDQLMFGTEDYLD
                     YQSLATIYEAKAEQMAAYVADLPEYLSYPQKTQHMWQALADVSFTGDKPNHILALAYT
                     KACAGKGIALTPIKRQGAGYHSKNKLHQFASATAIRKHLSDKAFVDKSVPDASLLLTS
                     PQVSWDNYFQLLTYQILTHADLTQIVQVNEELANRISAAIRTVETIDELIDQVATKRY
                     TKARVRRVLTYILVNAMETSLPEAVHVLGFSDKGRVHLKSLKQRVSIVSRIGSEPWDA
                     LTQQADAIYQLGNPAMAEQTWGRWPIMRTEK"
     gene            7858..8571
                     /locus_tag="VB649_000144"
     CDS             7858..8571
                     /locus_tag="VB649_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEP1669130.1"
                     /translation="MKTVKEVSQLVGLSVRTLHYYDEIDLLKPTLVGDNGYRFYDDYA
                     LAQLQDILLFRELDFPLKTIKTLLNSPAYVQGAALADQIRLLEMRQQHLQELIQHARA
                     LQEGGEQMGFKAYDHSHIQAFEEEVKERWGKTDAYVAYATKTAMKPEQLWQDMREIFR
                     GFGDIKDQAVSSQAAQKQVAKLQDYISQNLYPCEMEILESLGLMYVSDQRFKETIDQM
                     VGIGTATFVSRAISHYCQS"
     gene            9230..11602
                     /locus_tag="VB649_000145"
     CDS             9230..11602
                     /locus_tag="VB649_000145"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEP1669131.1"
                     /translation="MKHDGHSHFFFYSDLKGSKWDYLIPKGYKDASRQETTSAATSKA
                     STTGHHGDAHASDGYVFNPNDIVSEDVNGYTVRHGDHYHYIWKKDLVVTARPTVQQGP
                     QQSPSTNSSSAHHKDNKQSNGSENGNHHDNIGSQHNHVDPLGAYRVNAEGKKEFSGIH
                     YATSDDFLFDGKHIIGNTADGLLVAHNGRKEDVHLVPSAQLVDSKWAHLIPEDKRQQA
                     EKHYHGEADETPKTSEKGQVMTGEDFVNQAKDLDPKFQRIILDKIERVFRTNAGCSKE
                     ELLPLIKIDLENNLFTYPHDDHSHMEPIDASKPFGNGDKIYDFVDYNLPGKPELEKHD
                     VIGPIFTNTNSSRDLDKKKLLETHPELKEQILDINSFYALSFLAQDSGGQEGYIKQPG
                     SLRVGSQETQAVTYLIKKGQTINNLKIEVPTPLAKEQYFFKKWSSQLPTDGKLEKDWV
                     LTAAFRHDKHKNTQAFFTGDPKDLDVNIGDYSVVNFTTLNHGKLNYKGNSLAGFSFRV
                     RNNLTWKSVLDSGFIFPTPVPNDDNIEFIRWGGSVDFPEGAAVNNKVEASIFLAKFGL
                     KRPIIGAYVPSDAKNPTKTDDPKRLHPNSVTDPYDESKYMTIVIDAGEHATLRTHSTE
                     SRQLAFVVRQGTTWDEFAKTLVKVAVIPEKGYVYKGHDLALSKGSDKVQPGVYKEIVV
                     EQASDKDKKPSQDNWLDEFTKAEEKDTPEKTDGAKPGKEAEAEKPVGPKSETNSPEKA
                     DKEPQNATPISPSTDQEKPNKWHLGDDEPVSGEPAPLPPVSEEDGDDLLP"
     gene            11765..12691
                     /gene="bioB"
                     /locus_tag="VB649_000146"
     CDS             11765..12691
                     /gene="bioB"
                     /locus_tag="VB649_000146"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HEP1669132.1"
                     /translation="MNKTEALAILTSGADWWQYYAQAILVKQEKSGNRIRLNTLLNAK
                     SGLCSEDCGYCAQSKDSKAPINRYGLLPKDEIIRKALIAKKNKSSVFCIALSGTRPTT
                     REIALLCDAIQEIKHAMDMEICLSIGLVTKEQIQLLKEAGVDRLNHNINTPRENYDKI
                     TTTHTYQDRVDTLEMLNEIGVDTCSGFICGMGETDQQLVDMAFELKTLGPYSVPVNFL
                     LPIDGTKLEGHHQLTPTKYLKILVMLRLLFPETELRVSAGREYHLGELQQMALLIVDS
                     IFLGNYLTEKGADISDDQKMIDQLGLAVEGVC"
     gene            12860..13576
                     /locus_tag="VB649_000147"
     CDS             12860..13576
                     /locus_tag="VB649_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP1669133.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRTAYGKNGGNMGASGSVSYLFDKKGVIVFAGDDADSVFEQLLEADVDVDD
                     VEAEEGTITVYTAPTDLHKGIQALRDNGVEEFQVTELEMIPQSEVVLEGDDLETFEKL
                     IDALESDDDVQKVYHNVADF"
     gene            13779..14621
                     /locus_tag="VB649_000148"
     CDS             13779..14621
                     /locus_tag="VB649_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP1669134.1"
                     /translation="MIKKQYLGRATIALASTLVLAACGSSKKAESGNQGSSKEVLFAT
                     VGTTAPFSYEKGGQLTGYDIEVAKAVFKGSDDYKVSFKKTEWSSIFTGLDSGKYQMGG
                     NNISFTKERSAKYLFSYPIGSTPSVLVVPKDSDIKSFDDIQGHTTQVVQGTTSVAQLE
                     DFNKKHSDNPVTLKFTNENITQMLTNLSEGKADFKIFDAPTVNAIIKNQGLDNLKTIE
                     LTSTEQPFIYFIFSQDQEKLQSFVNKRIKELTADGTLSKLAKEHLGGDYVPSDKELKL
                     PTAN"
     gene            14949..15794
                     /locus_tag="VB649_000149"
     CDS             14949..15794
                     /locus_tag="VB649_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEP1669135.1"
                     /translation="MSFKKWIGIVGIALASTVLVACSEKQDDKNTLTIGVMTKTESDQ
                     ARWDKVEELLKKDNITLKYKEFTDYSQPNKAVANGEVDINAFQHYNFLNNWNKENKEH
                     LVAIADTYISPINLFSGTSQDGKAKYKSVADLPNGAQIAVPNDAANESRALYVLQSAG
                     LIKLNVSGDQLATIANISENKKKLDIKELDASQTARALVSADAAVVNNSYAVPAKIDY
                     KTSLFKEKADDNSKQWINIIAGQKDWEKSEKADAIKKLIKAYQTDEVKKVVEKTSNGI
                     DVSVW"
     gene            16044..17108
                     /locus_tag="VB649_000150"
     CDS             16044..17108
                     /locus_tag="VB649_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEP1669136.1"
                     /translation="MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSADALRQKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICN
                     RVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANA
                     LLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENIL
                     AAEKALHEAGVDVSILKRGA"
     gene            17109..17801
                     /locus_tag="VB649_000151"
     CDS             17109..17801
                     /locus_tag="VB649_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669137.1"
                     /translation="MSQLIQTYLPNVYELGWSGDAGWGLAIWNTLYMTIVPFIVGGAI
                     GLLLGLLLVLTGPDGVIENKTICWVIDKVTSVFRAIPFVILIAILASFTYLLLRTTLG
                     ATAALVPLTFATFPFYARQVQVVFSELDKGVIEAAQASGATFWDIVKVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATIIILLIIFAIQF
                     IGDSLTRRFSHK"
     gene            complement(17855..19225)
                     /gene="brnQ"
                     /locus_tag="VB649_000152"
     CDS             complement(17855..19225)
                     /gene="brnQ"
                     /locus_tag="VB649_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEP1669138.1"
                     /translation="MKQKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGHQILWSIIG
                     FCLTGVSLPLLGVIAVAKSGSGDVESLARPISKWYAIFYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDNTTNKAIYAILFFGLSYFLAIKPSKLAENIGKFLTPTLLVVISIL
                     VIASFVHPAGNYGDAFNAGVGVNNAFKDFPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDKEVTKITLISGAIAILLLALVYIFVGRIGATSQSLFPFIDGSFTLHGNPV
                     NGGQILSHASRFYLGGIGQAFLAVVIFLACLTTSTGLITSSAEYFHKLVPALSHIAWA
                     TIFTLLSAFFYFGGLSVIINWSAPVLFLLYPLTVDLIFLVLAQKCFNNDPIVYRTTIG
                     LTFIPAIFDALLTLSQMTVLFHLPEAVVTFFQKTVPLGQFSMGWIIFAAIGFLIGLIL
                     SKTKKS"
     gene            19459..20673
                     /gene="sstT"
                     /locus_tag="VB649_000153"
     CDS             19459..20673
                     /gene="sstT"
                     /locus_tag="VB649_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEP1669139.1"
                     /translation="MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLF
                     VGGLKAIAPLLVFALVSQAISHQKKGRQTNMTLIIVLYLFGTFVSALVAVLTAYLFPL
                     TLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKA
                     ASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLV
                     GTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKI
                     GLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSAC
                     GASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKRKKA"
     gene            complement(20728..21402)
                     /locus_tag="VB649_000154"
     CDS             complement(20728..21402)
                     /locus_tag="VB649_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEP1669140.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNFDQDVIAIDIRESHVKEVA
                     DLVTKAAVGDITDKEFLLAVGIEHCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRRHIESIIYLEHGISMIEFVIPKSW
                     EGQSLSELDVRRKYELNVIGMRQKEVKTLDTNVKPFEPLEPNTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(21412..22803)
                     /locus_tag="VB649_000155"
     CDS             complement(21412..22803)
                     /locus_tag="VB649_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEP1669141.1"
                     /translation="MSGGNMKRSFIKSLSVTQRLTFSFAIVILIGTLLLSMPFTHYQN
                     GPNTVYLDHFFNVVSMVCVTGLSVVPVAEVYNGIGQTIAMALMQIGGLGLVTLIAVST
                     FALKRKMRLSDQTLLQSALNRGDSKDLKHYLFFAYKVTFSLEAFAALVIMIDFIPRFG
                     WKNGIFNSIFLAVSAFCNAGFDNLGSSSLKDFMLNPTLNVIITFLIISGGLGFAVWVD
                     LGVAFKKYFFERPHCYGATFRKLSNQSRLVLQTTAVILFLGTFLTWFLEKDNSKTIAN
                     FSLHQQLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKVT
                     TAAITFLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGFILLLSVEPH
                     IAPIPLLFESISAIATVGVSMDLTPQLSTAGRLIVIVLMFVGRVGPITVLISLIQRKE
                     KTIQYATTDILVG"
     gene            complement(22872..23585)
                     /gene="rsmG"
                     /locus_tag="VB649_000156"
     CDS             complement(22872..23585)
                     /gene="rsmG"
                     /locus_tag="VB649_000156"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEP1669142.1"
                     /translation="MTPQDFYRTLEKDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAI
                     TEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDS
                     LNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELT
                     IPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKK
                     KETPNKYPRKAGLPNKKPL"
     gene            23735..24292
                     /locus_tag="VB649_000157"
     CDS             23735..24292
                     /locus_tag="VB649_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEP1669143.1"
                     /translation="MPTVLIILVVLGVLALWLMISYNSLVKSRMHTKEAWSQIDVQLK
                     RRNDLIPNLIETVKGYASYEQKTFEKITDLRARVANASTPQETMAASNELSKQVTSLF
                     AVAENYPDLKANENFLKLQEELTNTENKISYSRQLYNSTTSNYNLQLESFPSNIAGKL
                     FGFKPSEFLQTPEAEKEVPKVEFNF"
     gene            24339..25235
                     /gene="htpX"
                     /locus_tag="VB649_000158"
     CDS             24339..25235
                     /gene="htpX"
                     /locus_tag="VB649_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEP1669144.1"
                     /translation="MLYQQISQNKQRTVVLLVVFFALLALIGASAGYLLLDNYAMGLV
                     LALVIGVIYATSMIFQSTSLVMSMNNAREVTEKEAPGFFHIVEDMAMVAQIPMPRVFI
                     IEDPSLNAFATGSSPQNAAVAATTGLLEVMNREELEGVIGHEISHIRNYDIRISTIAV
                     ALASAVTVISSIGGRMLWYGGGSRRQRDDGDDDVLRIITLLLSLLSLLLAPLVASLIQ
                     LAISRQREYLADASSVELTRNPQGMIKALEKLQLSQPMKHPVDDASAALYINEPRKKR
                     SFSSLFSTHPPIEERIERLKNM"
     gene            25469..26002
                     /locus_tag="VB649_000159"
     CDS             25469..26002
                     /locus_tag="VB649_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEP1669145.1"
                     /translation="MLAISEIRKHPDGLSFDRLCDVKSMLLERDQQIIDIKAVKAVGN
                     VRYDKGLYLLDYQLSYEVILPSSRSMVPVCLSEVQHIQELFIEATDLADKKELVEDNL
                     VLVLDKDAINLEESIVDNILLAIPLQVLTEEEKKSKELPAGQNWAVLTEEDYQCLKEE
                     KQKENNPFASLQGLFDE"
     gene            26269..26955
                     /gene="covR"
                     /locus_tag="VB649_000160"
                     /gene_synonym="csrR"
     CDS             26269..26955
                     /gene="covR"
                     /locus_tag="VB649_000160"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEP1669146.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALE
                     KEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            26961..28463
                     /gene="covS"
                     /locus_tag="VB649_000161"
                     /gene_synonym="csrS"
     CDS             26961..28463
                     /gene="covS"
                     /locus_tag="VB649_000161"
                     /gene_synonym="csrS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CovS"
                     /protein_id="HEP1669147.1"
                     /translation="MENQKQKQKKYKNSLPKRLSNIFFVLFFCIFSAFTLIAYSSTNY
                     FLLKKEKQSVFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDKTHLRIDDRKGSRVIRS
                     ERDITNTLDANQDIYVYNIDKQMIFTTDNEESSPGLHGPIGRVYHDHIEDQYRGFSMT
                     QKVYSNRTGKFVGYVQVFHDLGNYYVIRARLLFWLLVVELFGTSLAYLIILITTRRFL
                     KPLHNLHEVMRNISENPNNLNLRSDISSGDEIEELSVIFDNMLDKLETHTKLQSRFIS
                     DVSHELRTPVAIIKGHIGLLQRWGKDDSDILEESLTATAHEADRMAIMINDMLDMIRV
                     QGSFEGHQNDMTVLEDSIETVVGNFRVLREDFIFTWQSENPKTIARIYKNHFEQALMI
                     LIDNAVKYSRKEKKIAINLSVTGKQEAIVRVQDKGEGISKEDIEHIFERFYRTDKSRN
                     RTSTQAGLGIGLSILKQIVDGYHLQMKVESELNEGSVFILHIPLAQSKES"
     gene            28678..29172
                     /gene="nrdR"
                     /locus_tag="VB649_000162"
     CDS             28678..29172
                     /gene="nrdR"
                     /locus_tag="VB649_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEP1669148.1"
                     /translation="MRCPKCNYHKSSVVDSRQAEDGNTIRRRRECEQCHTRFTTFERV
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENVISRIEQEVRTTYENE
                     VSSTAIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITNRVRGKKKRLNN
                     DETN"
     gene            29156..30331
                     /locus_tag="VB649_000163"
     CDS             29156..30331
                     /locus_tag="VB649_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEP1669149.1"
                     /translation="MMKPIDTFTYLKRNKVTLDSVTLIQLYFPIIGSDAVSIYQYFIH
                     FFDDGLQRHKFSDILNHLQFGMKRFEDALAILTAMELVSVYQLSDTYLITLHQPLSRD
                     LFFQHPAYSRLLEQKIGEVAVSELQVTVPSQARNISKRFSDIFGVQGNLTNVPQKPQK
                     NFDLSSFQQLMVRDGLQFEDNQKDIISLYSIAEQYDMTWFDTYQIAKATAVNGKIRPE
                     RLLAKKNQSMTKPSKENFSQAEQIILREAKQDSALVFLEKIKKARRATITKDERILLQ
                     TLAKMNFLDDVINVMVLYTFNKTKSANLQKSYVLKMANDFAYQKVSTAEEAIVVLRAF
                     TDRQSRRQSKVKTSQSNVPKWSNPDYQETTSQEEQAKLDQFKQAALKRLENLGKGGD"
     gene            30332..31234
                     /gene="dnaI"
                     /locus_tag="VB649_000164"
     CDS             30332..31234
                     /gene="dnaI"
                     /locus_tag="VB649_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEP1669150.1"
                     /translation="MEKIGETMAKLGQNTRVNSDQLIQTILADPEVASFISQHHLSQE
                     QINLSLSKFNQFLVERQKYQLKDPSYIAKGYQPILAMNEGYADVSYLETKELVEAQKQ
                     AAISERIQLVSLPKSYRHIHLSDIDVNNASRMEAFSAILDFVEQYPSAEQKGLYLYGD
                     MGIGKSYLLAAMAHELSEKKGVSTTLLHFPSFAIDVKNAISNGSVKEEIDAVKNVPVL
                     ILDDIGAEQATSWVRDEVLQVILQYRMLEELPTFFTSNYSFADLERKWATIKGSDETW
                     QAKRVMERVRYLAREFHLEGANRR"
     gene            31297..32607
                     /gene="der"
                     /locus_tag="VB649_000165"
     CDS             31297..32607
                     /gene="der"
                     /locus_tag="VB649_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEP1669151.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAQIAMEEADVIVFVVSGKEGVTDADEY
                     VSKILYRTNTPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIV
                     ENLPVEEAEENDDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DADGQEFTMIDTAGMRKSGKIYENTEKYSVMRAMRAIDRSDVVLMVISAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTIDKDNHTVAKWEADIRDQFQFLTYAPIIFVSALTKQ
                     RLNKLPDLIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIHLIARKRK"
     gene            32814..35912
                     /locus_tag="VB649_000166"
     CDS             32814..35912
                     /locus_tag="VB649_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP1669152.1"
                     /translation="MMARLIPGRVRNEGIKLYEQGLVSFQDDNKGILQIEVETYQVQY
                     GADDEDITCQCDTFHMKHYCKHIAAVEYFLKNDQKGKLFLKQLTNQTKIKETTKKMTS
                     FGSLFLDSLAMNEDDSVKYRLSALGSRSPFSSDYWWSLKINRLPDDRSYVIRDIKGFL
                     QLIKKEGFYQIGKNYFEQLSWLQFDPSSQDLIEFLWRLASDTDKGDNENIFPNHARHL
                     RLPSGFFEEGIHYLTSLYDFTFEGPSQTYHHLFVRSLEAEAGLYEFKVEVHRKSIELQ
                     IAEKNVQYLFDNDYLLYQDTFYHLTLKQRKMVQAIRSLPIETDLAKHIHFDLDDHAKL
                     AASLSDFKQIGLVEAPKSFAIRDFEVTFQFDLLNRDEISCQLMFDYGNYQVSDKASLE
                     ALPFASHLKKEEKINRSLLAFGFSPQFYSKKRLTSAKELYTFFEETVPCFERLGNVAL
                     STAIQALQVKEMPKIAIRRNQGLLDISFDFSTIIENDIDQAVTALFQNNPYFVSQTGQ
                     LVVFDDETQKVSKSLQELRARQLKNGHLQLDGIRALQVSKLFEGMTSVHFSKELEELA
                     YHLQHPETFSIKPLPVKAQMRDYQRNGVQWLSMLNHYGFGGILADDMGLGKTLQTLAF
                     LASHLKSDSKVLILSPSSLIYNWFDECQKFTPQLDVVVSYGLKQIRDQIIEEGHQITI
                     TSYSSFRQDFETYQAFHYDYLILDEAQVIKNAQTKISHCLRAFNTANCFALSGTPIEN
                     KMLEIWSIFQIVLPGLLPTKKEFLKLTAEQVSRYIKPFVMRRKKEDVLPELPDLIETN
                     YSNEMTDEQKAIYLAQLRQMQDQIRNSSDVDISRQKIEILSGITRLRQICDTPSLFMD
                     YQGKSGKLDSLRILLTQIKENGHRALIFSQFRGMLDLAKQEMTALGLTSYQMTGSTPA
                     NERQEMTRAFNNGSKDAFLISLKAGGVGINLTGADTVILIDLWWNPAVEMQAISRAYR
                     IGQKENVEVYRLITRGTIEEKILELQESKRNLVTTVLDGNESRASMSIEEIKEILGLN
                     TH"
     gene            36154..36756
                     /locus_tag="VB649_000167"
     CDS             36154..36756
                     /locus_tag="VB649_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669153.1"
                     /translation="MVKNQFPLVADGIAISDPAKQMALYENEDLITNIRGYYQDKEYD
                     DIARNEEFTAKATSRQAPSSKRFCSDDEKHHYVKEARQKAKQDLKEKRQAYLAKEMAY
                     VPKQVSKKQQPADSSPSQKQATTEMSRFTKKLHQDNYILAELPKEYKEPKNLPQQGTT
                     KKNNYDFLKSSQIYNNKEMRQQREKTIAQELNLSRFEDLP"
     gene            36796..38124
                     /locus_tag="VB649_000168"
     CDS             36796..38124
                     /locus_tag="VB649_000168"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEP1669154.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNITPDMELIVGNAFRENNKEVAYALRHQIPFKRYHDFLGDFMKSF
                     ISFAVAGAHGKTSTTGLLSHVLKNITDTSYLIGDGTGRGSANAQYFVFESDEYERHFM
                     PYHPEYSIITNIDFDHPDYFTGIADVRNAFNDYAKQVKKALFVYGEDDELKKIEAPAP
                     IYYYGFEEGNDFIAYDITRTTNGSDFKVKHQGEVIGQFHVPAYGKHNILNATAVIANL
                     FVAGIDMALVADHLKTFSGVKRRFTEKIINDTIIIDDFAHHPTEIVATIDAARQKYPS
                     KEIVAIFQPHTFTRTIALLEDFACALNEADSVYLAQIYGSAREVDKGEVKVEDLAAKI
                     IKPSQVVTVENVSPLLDHDNAVYVFMGAGDIQLYEHSFEELLANLTKNNQ"
     gene            38170..38652
                     /locus_tag="VB649_000169"
     CDS             38170..38652
                     /locus_tag="VB649_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP1669155.1"
                     /translation="MLIRQVQGSDLEVIATIESDNFSPQEATTRAVLEERIRLIPDTF
                     LVALIGQEIVGYIEGPVVTTPILEDSLFHGVTKNPKTGGYIAITSLSIAKHFQQQGVG
                     TALLAALKDLVVAQQRTGLILTCHDYLISYYEMNGFINQGISESQHGGTLWYQMIWKL
                     "
     gene            38764..40338
                     /gene="mltG"
                     /locus_tag="VB649_000170"
     CDS             38764..40338
                     /gene="mltG"
                     /locus_tag="VB649_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEP1669156.1"
                     /translation="MALTDFKDKDQQDQQRSFKEQILAELEKANQIRKEKEEELFQKE
                     LEAKEAARRTAQLYAEYKRQDAFQKESIAHNNKTAKHSQAIKDAVMTSEALKPTLLSE
                     KENSSLKTTNKRVVQANELQETASKESQAPLTIEKGHSVRRKLSKRQQTERAAKKIST
                     VLISSIIITLLAVTLAGAGYVYSALNPVDKNSDAFVQVEIPSGSGNKLIGQILQKKGL
                     IKNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEEIASALQEGGTAEPTKPSLGKILIP
                     EGYTIKQIAKAVEHNSKGKAKKAKTPFNEKDFLDLVTDEAFIQDMVKRYPKLLATIPT
                     KEKAIYRLEGYLFPATYNYYKETTMRELVEDMLAAMDATLVPYYDKIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNSGMALQSNIAILYAMGKLGEKTTLAEDATI
                     DTTINSPYNIYTNTGLMPGPVASSGVSAIEATLNPASTDYLYFVANVHTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            40410..40892
                     /gene="greA"
                     /locus_tag="VB649_000171"
     CDS             40410..40892
                     /gene="greA"
                     /locus_tag="VB649_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEP1669157.1"
                     /translation="MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTD
                     KDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
                     "
     gene            complement(41511..42434)
                     /gene="yidC"
                     /locus_tag="VB649_000172"
     CDS             complement(41511..42434)
                     /gene="yidC"
                     /locus_tag="VB649_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEP1669158.1"
                     /translation="MKLTLNRILFSGLALSILFTLTGCVGRDAHGNPKGMIWEFLGKP
                     MSYFIDYFANNAGLGYGLAIIIVTIIVRTLILPLGLYQSWKASYQSEKMAFLKPVFEP
                     INKRIKQASSQEEKMAAQTELMAAQRAHGINPLGGIGCLPLLIQMPFFSAMYFAAQYT
                     KGVSTSTFMGIDLGSRSLVLTAIIAALYFFQSWLSMMAVSEEQREQMKTMMYTMPIMM
                     IFMSFSLPAGVGLYWLVGGFFSIIQQLITTYLLKPRLHKQIKEEYAKNPPKAYQSTSS
                     RKDVTPSQNMEQANLPKKIKSNRNAGKQRKR"
     gene            complement(42516..42794)
                     /locus_tag="VB649_000173"
     CDS             complement(42516..42794)
                     /locus_tag="VB649_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEP1669159.1"
                     /translation="MQKVRLIVSGRVQGVGFRYATYALALDIGDIYGRVWNNNDGTVE
                     ILAQSKDSDKIATFIQEVRKGPSKWAKVTYVDVTMANFEDFQDFQIGK"
     gene            43055..43792
                     /locus_tag="VB649_000174"
     CDS             43055..43792
                     /locus_tag="VB649_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEP1669160.1"
                     /translation="MVITSKANQLIKQTKKLLQKKHRKQSYLIEGWHLFEEAQKSGQV
                     FRHIFVLEEMVERLAGEQELVIVSPQVLKELTDSPSPQGIVAEVEIPKLAFPSDYKGK
                     YLVLEDVQDPGNLGTIIRTADAARFDGVFLSEKSADIYNQKTLRSMQGSHFHLPIWRT
                     DVYQLCRELQEYKTPILATTLSKKSVDYKSLTHHERLALVLGNEGQGISAEMAALADQ
                     LVHITMPGQAESLNVAVAAGILIFSLI"
     gene            43831..44331
                     /locus_tag="VB649_000175"
     CDS             43831..44331
                     /locus_tag="VB649_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEP1669161.1"
                     /translation="MHYTEDKEYMEHVGHLIAHPRFQKLSHIVQHQHSTRLEHSINVS
                     YSSYKLAKRFGWDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTEL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTMVDKYWAVKEAVTPLRQKWSNRRFLRRKT
                     LQSHNR"
     gene            44346..45035
                     /locus_tag="VB649_000176"
     CDS             44346..45035
                     /locus_tag="VB649_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEP1669162.1"
                     /translation="MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFR
                     ENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYSALNGFTLSFII
                     VAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIG
                     SGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRIFGRND"
     gene            45213..45455
                     /locus_tag="VB649_000177"
     CDS             45213..45455
                     /locus_tag="VB649_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEP1669163.1"
                     /translation="MSTAIWILLLIVALGVGVFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIIKQSKAAVSKGKK"
     gene            45633..46427
                     /gene="racE"
                     /locus_tag="VB649_000178"
     CDS             45633..46427
                     /gene="racE"
                     /locus_tag="VB649_000178"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEP1669164.1"
                     /translation="MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGP
                     RPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAVLDIPVLGVILPGASA
                     AIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
                     AKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLL
                     NYFDINGNYHQKAVKHRFFTTANPEIFQEIASIWLKQKINVEHVTL"
     gene            46424..47410
                     /locus_tag="VB649_000179"
     CDS             46424..47410
                     /locus_tag="VB649_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEP1669165.1"
                     /translation="MSEKIYEYKDENNWFIGKMTGHNLISGWGVKYTTIKKIDDLLDG
                     ITATLDWENPKGYDVSVVRYQSPLSLITFIIDMINQETQRKIKITPHAGTILLMENAK
                     LLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQLGYRVENLNDY
                     PELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGP
                     DATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEAEWPGYIATQPKG
                     ENGFGYDPVFIVGETGRHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS"
     gene            47389..47910
                     /locus_tag="VB649_000180"
     CDS             47389..47910
                     /locus_tag="VB649_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEP1669166.1"
                     /translation="MASKTIIVMSDSHGDRDIVQAIKDKYLGQVDAIFHNGDSELNSS
                     DPIWAGIYVVGGNCDYDTGYPDRLVTRLGTVTIAQTHGHLYHINFTWDKLDYFAQEVA
                     ADICLYGHLHRPAAWQVGQTLFMNPGSVTQPRGEINEKLYARVELTDTQIKVDYFTRD
                     HKLYPSLSKEFKR"
     gene            47907..48368
                     /locus_tag="VB649_000181"
     CDS             47907..48368
                     /locus_tag="VB649_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEP1669167.1"
                     /translation="MIAKEFETFLMSHLDNYLIPEQDLAIFIDTHNADHVMLLLVSNG
                     FSRVPVITREKKYVGTISISDIMMYQSKRQLTDWEMSQTDIGEMVNTKIETISITSSL
                     TEIMHKLIDFPFLPVVDRANRFVGIITRKSILKAVNSLLHDFTDDYTIIKK"
     gene            48365..49111
                     /gene="xerD"
                     /locus_tag="VB649_000182"
     CDS             48365..49111
                     /gene="xerD"
                     /locus_tag="VB649_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEP1669168.1"
                     /translation="MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLL
                     YQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINT
                     DIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLSFQMLTLKTKKGVRVLPLS
                     QILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFIL
                     KEKLAGKSIIELSDILGLKSPMTLEKYYKS"
     gene            49111..49815
                     /locus_tag="VB649_000183"
     CDS             49111..49815
                     /locus_tag="VB649_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEP1669169.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIET
                     LQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVS
                     QALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKNNHTV
                     IERDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNEVISIFLASLELIKLHVVFV
                     EQFSNFGAIILRKEKK"
     gene            49812..50363
                     /locus_tag="VB649_000184"
     CDS             49812..50363
                     /locus_tag="VB649_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEP1669170.1"
                     /translation="MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQ
                     KYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQ
                     PITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHL
                     DELIEVSAVEPADEEIALFRTQD"
     gene            50485..51207
                     /locus_tag="VB649_000185"
     CDS             50485..51207
                     /locus_tag="VB649_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP1669171.1"
                     /translation="MRINKYIAHAGIASRRKAEELIKQGLVTLNGQVITDLATTVKSG
                     DVVEIEGSPIYNEEKVYYLLNKPRGAISSVSDDKGRKTVLDLLPQVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDTMIHPRNEIDKVYLARVKGIATKENLRPLTRGIVIDGKKTKP
                     ARYNIVRVEADKNRSIVELTIHEGRNHQVKKMFESVGLLVDKLSRTRFGTVDLKGLRP
                     GEARRLNKKEISQLHNLANTKK"
     gene            51204..51467
                     /gene="yidD"
                     /locus_tag="VB649_000186"
     CDS             51204..51467
                     /gene="yidD"
                     /locus_tag="VB649_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEP1669172.1"
                     /translation="MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGT
                     KGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA"
     gene            51645..52193
                     /locus_tag="VB649_000187"
     CDS             51645..52193
                     /locus_tag="VB649_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HEP1669173.1"
                     /translation="MTTKELINKNDKVKKARNHIVLFQPQIPQNTGNIARTCAATNAP
                     LHIIKPMGFPIDDRKMKRAGLDYWDKLELHFYDHLEQFINQCHGQLHLISKFAVNNYS
                     QATYADGDSHYFLFGREDTGLPEDFMREHAEKALRIPMNDEHVRSLNVSNTVCMVIYE
                     ALRQQGFQGLELKHTYEHDKLK"
     regulatory      52302..52425
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            52504..53067
                     /locus_tag="VB649_000188"
     CDS             52504..53067
                     /locus_tag="VB649_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP1669174.1"
                     /translation="MSKTHKMIMIGILSAISFLLMLVSFAIIPGAAFLKIEFSIIPVL
                     FGLMIMDLKSAYLILLLRSLLKLFLNNRGVNDFIGLPMNIIAIALFVTAFSLVWNRQK
                     TLSQYVFASLLGTGLLTFGMVVLNYTFAIPLYAIFANIDIRAYIGVTKYMMTMVIPFN
                     LVEGLIFAITFYFVYIASKPILERYLH"
     gene            53069..53722
                     /locus_tag="VB649_000189"
     CDS             53069..53722
                     /locus_tag="VB649_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEP1669175.1"
                     /translation="MMTNKQTNFLIASFALLTFVIIGYTVKFFPERLALLDNTIQAEI
                     RGNLPIVLTQFFRGVTVFGNVMTQILLVIVSVLVLFFMKWKIEALFILSNGAIAAFLI
                     TTLKLFYQRPRPAIEHLVYAGGYSFPSGHAMGSMLIFGSLLIICYQRLHSKLLQFVTS
                     MIFIILILVIGLSRIYLGVHYPSDILAGFVLGFGILQFIYPFYKQKRFEWRFLLKQD"
     gene            54015..54935
                     /locus_tag="VB649_000190"
     CDS             54015..54935
                     /locus_tag="VB649_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407327.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEP1669176.1"
                     /translation="MKKRYQTLNEHYRQLFGAKMFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIKEQFYKEIDFMHRKWPDVNRYLVYFQNFTNTHDTVDVIRD
                     RYEQAINEPGVVGINIGTRPDCLPDDTIAYLAELSERMHVTVELGLQTTYEETSRLIN
                     RAHSYDLYKETVRRLRHYPNINIVSHLINGLPKETHDMMLENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLKLLSQKDYVSIICDQLEIIPKHIVIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDKEMERRGSFQGCKVD"
     gene            54974..55528
                     /locus_tag="VB649_000191"
     CDS             54974..55528
                     /locus_tag="VB649_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP1669177.1"
                     /translation="MLKRPIHLSHDFLAEVVDKSSVVVDATMGNGNDTAFLAQLAKKV
                     YAFDVQEQAIRKTSERLAQLGLSNAELILAGHEAVDQYVTEPVRAAIFNLGYLPSADK
                     SIITLPNTTLQALSKLLTLLMVGGRIAIMVYYGHDGGSLEKDALLDFVKQLDQRKVSA
                     MLYQPLNQVNTPPFLIMLEKLADV"
     gene            55661..56995
                     /locus_tag="VB649_000192"
     CDS             55661..56995
                     /locus_tag="VB649_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEP1669178.1"
                     /translation="MEDPVSQPLVIQFLLLVVLTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKKYARLLRVLEEPNHFLSTIQVGITFISLLSGASLSASLGKVISGWLGNSATA
                     RTAGTIISLVFLTYVSIVLGELYPKRIAMNLKDKLAIVSAPIIIGLGRLVSPFVWLLS
                     ASTNLLSRLTPMTFDDADEQMTRDEIEYMLSKSEATLDAEEIEMLQGVFSLDEMMARE
                     VMVPRTDAFMIDINDDPLENIQEILKQSFSRIPVYDVDKDKIIGLIHTKRLLESGFRQ
                     GFDQINMRKMLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHEIGDNTYIVVGTMTLNEFNDYFDTELESDDVDTIAGFYLT
                     GIGTIPSQEQKEAYEIDNKDKHLVLINDKVKDGRITKLKLILSNIEQIIEED"
     gene            57073..57864
                     /gene="pflA"
                     /locus_tag="VB649_000193"
     CDS             57073..57864
                     /gene="pflA"
                     /locus_tag="VB649_000193"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEP1669179.1"
                     /translation="MTEKDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKLRCQYCH
                     NPDTWEMETNNSKIRTVNDVLKEALQYKHFWGKKGGITVSGGEAMLQIDFITALFIEA
                     KKLGIHTTLDTCGFTYRPTPEYHQVLDNLLAVTDLILLDLKEIDEKQHKIVTRQPNKN
                     ILQFARYLSDKQIPVWIRHVLVPGLTDIDDHLTRLGEFVKTLKNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVQNAKNLMQTESYTEYMNRIHQS"
     gene            57995..58930
                     /locus_tag="VB649_000194"
     CDS             57995..58930
                     /locus_tag="VB649_000194"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEP1669180.1"
                     /translation="MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPN
                     EETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
                     HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERQEAIEAAIKDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKV
                     EAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            59006..59659
                     /locus_tag="VB649_000195"
     CDS             59006..59659
                     /locus_tag="VB649_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEP1669181.1"
                     /translation="MITVFHSDKLTRQPFFQDLINYLDQHDHVILREIKKAFPNVTGI
                     DKAIESYVKAGYIRRENKRYGINLPLVSSDQQLALDTMLFVDTCSAMYENILAVVFET
                     QLTNQTNHVMIKEKTNITRDDLTLANYFYRLKRGEKPSAEQMDLYDLLGDVNQEYALK
                     YMTTFLLKFTRKDLVMQKRPDIFVEALVTLGYLKQVEPTTYQLLMTLDKESLTFIAP"
     gene            complement(59704..60741)
                     /locus_tag="VB649_000196"
     CDS             complement(59704..60741)
                     /locus_tag="VB649_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP1669182.1"
                     /translation="MLFMVNKERRPLLKSHRHLLGLYTSLILLLVSLMGLALSLGESH
                     LSFLDLIHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQRLTRNPLADS
                     GVLGITIGAGISLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQID
                     STRLILTGVAVTTMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLL
                     CFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKRRLILVLAAGLGALSVLLVGNISFI
                     GLIAGHFSTYLVGSNHKLTIPISILIGMILLLVADTIGRVYLVGSNIQTGILVSLIGA
                     PYFLYLMVKTK"
     gene            complement(60702..61754)
                     /locus_tag="VB649_000197"
     CDS             complement(60702..61754)
                     /locus_tag="VB649_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP1669183.1"
                     /translation="MKTKHPFLCLERFCLKKTQIITKSHIFWLVFVLLSFSLCVAIYC
                     HLRFGAVALSHQDLNSILFGKQNGHKANVLLAIRLPRLFGATLTGSALAVSGTIMQAI
                     TRNPIAEPGLLGINAGAGLALVLAYAFVPHLHYSLIILLSLLGSSLAATLVFGLSYQS
                     GKGYHQLRLVLAGAMVSILLSALGQGITNYYHLANAVIGWQAGGLVGVNWQMIGYIAP
                     LIILSLCLAQLLSYHLTVLSLSESQAKALGQKTNLISAVFMILVLILSSAAVAIAGSI
                     SFIGLVIPHLMKHFTPHHYRYLLPLCAVSGASFMVWVDIACRNLNPPYETPLGALVSL
                     IGFPCFLWLIRRGGRY"
     gene            complement(61744..62676)
                     /locus_tag="VB649_000198"
     CDS             complement(61744..62676)
                     /locus_tag="VB649_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEP1669184.1"
                     /translation="MKKLTLLLTLCLTTITLIACGNQATNHSNTASKSLSPMPQIAGV
                     TYYGDIPKQPKRVVSLASTYTGYLKKLDMNLVGVTSYDKKNPILAKTVKKAKQVAATD
                     LEAITTLKPDLIVVGSTEENIKQLAEIAPVISIEYRKRDYLQVLSDFGRIFNKEGKAK
                     KWLKDWKTKTAAYEKEVKAVTGDKATFTIMGLYEKDVYLFGKDWGRGGEIIHQAFHYD
                     APEKVKTEVFKQGYLSLSQEVLPDYIGDYVVVAAEDDKTGSALYESKLWQSIPAVKKH
                     HVIKVNANVFYFTDPLSLEYQLETLREAILSSEN"
     gene            complement(62702..63484)
                     /locus_tag="VB649_000199"
     CDS             complement(62702..63484)
                     /locus_tag="VB649_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669185.1"
                     /translation="MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSS
                     LLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLALLPQVQEATNGITVYELVSYGR
                     FPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
                     IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIIMVLHDLNLSARYSDHLIAMKHGKI
                     HYTGTIADVMTSPIIQDIFQIKPVLVDDPIHNCPIVLTYQLQ"
     gene            complement(63730..65175)
                     /locus_tag="VB649_000200"
     CDS             complement(63730..65175)
                     /locus_tag="VB649_000200"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEP1669186.1"
                     /translation="MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQ
                     VDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMA
                     FYGNPQDQLKLLGFTGTKGKTTAAYFAYHILKESYKPALLSTMNTTLDGKTFFKSQLT
                     TPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQA
                     FSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEV
                     LTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIH
                     QHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAV
                     IIAGKGADAYQIVKGQQVAYAGDLAIAKHYL"
     gene            65263..66897
                     /locus_tag="VB649_000201"
     CDS             65263..66897
                     /locus_tag="VB649_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEP1669187.1"
                     /translation="MSTEKKQLTQEELMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQTEHSYQLIRSTLKL
                     MLGLGLIFSAIMYLGSPLFASLSGGDDTLVPIMHSLSLAVFIFPVMSVIRGIFQGHNN
                     IKPYAVSQIAEQLIRVIWMLLTTFFIMKLGSGDYASAVTQSTFAAFIGMVASMGVLGY
                     YLWKQGLLAAIFSKPDHTVSIDIKGLLLETLKESIPFIVTGSAIQAFQLIDQWTFVNT
                     MTLFTDYSRSQLLVLFGYFNANPAKITMVLIAVAASIGGVGIALLTENYVKKDMKAAA
                     RLIINNIEMLVMFLLPALTGAIILARPLYSVFYGASEERAIHLFVAVLFQTLLLALYT
                     LFSPMLQALFENRKAIYYFAYGILIKLVLQIPLIYLLHAYGPLLATTIALVVPIYLMY
                     RRLYQVTHFNRKLLQKRLLLTLIETLLMGLVVFVANWLLGYAFKPTGRLTSLLYLLII
                     GGLGMTVYTALTLLTHQLDKLIGSKASRLRQKLGWH"
     gene            67065..67694
                     /gene="upp"
                     /locus_tag="VB649_000202"
     CDS             67065..67694
                     /gene="upp"
                     /locus_tag="VB649_000202"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEP1669188.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQTTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVDIQTPVSKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDINQRQIFLVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDIDIFTAALDDHLNEHGYIVPGLGDAGDRLFGTK"
     gene            67918..68508
                     /locus_tag="VB649_000203"
     CDS             67918..68508
                     /locus_tag="VB649_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEP1669189.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK"
     gene            69003..69278
                     /locus_tag="VB649_000204"
     CDS             69003..69278
                     /locus_tag="VB649_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEP1669190.1"
                     /translation="MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYIN
                     KNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG"
     gene            69527..70162
                     /locus_tag="VB649_000205"
     CDS             69527..70162
                     /locus_tag="VB649_000205"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEP1669191.1"
                     /translation="MITGKLITVEGPDGAGKTTVLEQLIPLLKQKVAQDILTTREPGG
                     VAISEHIRELILDINHTAMDPKTELLLYIAARRQHLVEKVLPALEAGQLVFIDRFIDS
                     SVAYQGAGRGLIKADIQWLNEFATDGLEPDLTLYFDVPSEIGLARINANQQREVNRLD
                     LETIEIHQRVRKGYLALAKEHPKRIVTIDATKPLKEVVSVALEHVLALLLA"
     gene            70180..71055
                     /locus_tag="VB649_000206"
     CDS             70180..71055
                     /locus_tag="VB649_000206"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEP1669192.1"
                     /translation="MDLAQKAPNVYQAFQTILKKDRLNHAYLFSGDFANEEMALFLAK
                     VIFCEQKKDQTPCGHCRSCQLIEQGDFADVTVLEPTGQVIKTDVVKEMMANFSQTGYE
                     NKRQVFIIKDCDKMHVNAANSLLKYIEEPQGEAYIFLLTNDDNKVLPTIKSRTQVFQF
                     PKNEAYLYQLAQEKGLLNHQAKLVAKLATNTSHLERLLQTSKLLELITQTERFVSIWL
                     KDQLQAYLALNRLVQLATEKEEQDLVLTLLTLLLARERAQTPLTQLEAVYQARLMWQS
                     NVNFQNTLEYMVMSE"
     gene            71074..71313
                     /locus_tag="VB649_000207"
     CDS             71074..71313
                     /locus_tag="VB649_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tpl protein"
                     /protein_id="HEP1669193.1"
                     /translation="MGKRSLSKDLPVATKVAAHRGKKAFEENTAFATDLMKEVSRLIT
                     QNKLEMTFINSVFLLDQHVVLIPFSAEEHMDFYNC"
     gene            71717..72040
                     /gene="yabA"
                     /locus_tag="VB649_000208"
     CDS             71717..72040
                     /gene="yabA"
                     /locus_tag="VB649_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEP1669194.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLE
                     NTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            72045..72908
                     /gene="rsmI"
                     /locus_tag="VB649_000209"
     CDS             72045..72908
                     /gene="rsmI"
                     /locus_tag="VB649_000209"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEP1669195.1"
                     /translation="MQVQKSFKDKKTSGTLYLVPTPIGNLQDMTFRAVATLKEVDFIC
                     AEDTRNTGLLLKHFDIATKQISFHEHNAYEKIPDLIDLLISGRSLAQVSDAGMPSISD
                     PGHDLVKAAIDSDIAVVALPGASAGITALIASGLAPQPHVFYGFLPRKAGQQKAFFED
                     KHHYPETQMFYESPYRIKDTLTNMLACYGDRQVVLVRELTKLFEEYQRGSISEILSYL
                     EETPLKGECLLIVAGAQVDSEVELTADVDLVSLVQKEIQAGAKPNQAIKTIAKAYQVN
                     RQELYQQFHDL"
     gene            72935..73327
                     /locus_tag="VB649_000210"
     CDS             72935..73327
                     /locus_tag="VB649_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669196.1"
                     /translation="MTEDQATILILGVYGIILAVFLLSALLCLIANWRLFKRAGYKGW
                     YSLIPFYAGFVKHKITFGEDNKWFYFIGWVIAIYYYYVHFCYVRAFGGSKGLAVFGLF
                     FPGIASLIVAFGKTYTTQECHPVPHLLN"
     gene            complement(73374..74003)
                     /locus_tag="VB649_000211"
     CDS             complement(73374..74003)
                     /locus_tag="VB649_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEP1669197.1"
                     /translation="MIKEFCAENLTLLPTLDAGQVSRVELCDNLAVGGTTPSYGVIKE
                     ACQLLHDKNISVATMIRPRGGDFVYNDLELKAMEEDILKAVEAGSDALVLGLLTSENQ
                     LDTDAIEQLLPATQGLPLVFHMAFDHIPTDHQHQALDQLIDYGFVRVLTHGSPEATPI
                     TDNVEQLKSLVTYANKRIDIMIGGGVTAENCQSLSQLTGTAIVHGTKII"
     gene            74309..74665
                     /locus_tag="VB649_000212"
     CDS             74309..74665
                     /locus_tag="VB649_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEP1669198.1"
                     /translation="MITIYQYPKCSTCQRAMAELKQLVSDFEAIDIKANPPKAQDLKH
                     WMETSGYTIKNFFNTSGNSYRELGLKDKIDQLSLDKAAELLATDGMLIKRPILIKDGN
                     VLQVGYRKPYQELDLG"
     gene            complement(74739..75566)
                     /gene="xth"
                     /locus_tag="VB649_000213"
     CDS             complement(74739..75566)
                     /gene="xth"
                     /locus_tag="VB649_000213"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEP1669199.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHIEALLSYFPNYLRVWRSSVEPARKGYAGTMFLYKNTLNPVITFPEI
                     GAPTTMDAEGRIITLEFEDFFVTQVYTPNAGDGLRRLDDRQIWDHKYADYLTELDAQK
                     PVLATGDYNVAHKEIDLANPSSNRRSPGFTDEERQGFTNLLARGFTDTFRHVHGDIPH
                     VYTWWAQRSKTSKINNTGWRIDYWLASNRLVDKVKRSEMISSGERQDHTPILLDIDL"
     gene            75800..76981
                     /gene="lctO"
                     /locus_tag="VB649_000214"
     CDS             75800..76981
                     /gene="lctO"
                     /locus_tag="VB649_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEP1669200.1"
                     /translation="MAQKTVITEETTDFVMDFKTSSAEGNVDFINVFDLEKMAQQVIP
                     KGAFGYIASGAGDTFTLHENIRSFNHKLIVPHSLKGVENPSTEITFDGDHLTSPLILA
                     PVAAHKLANEQGEVASAKGLKEFGSIYTTSSYSTTDLPEISAALGGTPHWFQFYYSKD
                     DGINRNIMDRVKAQGCKAIVLTADATVGGNREVDRRNGFVFPVGMPIVQEYLPDGAGK
                     TMDYVYKSAKQALTSKDIEYIATYSGLPVYVKGPQCAEDTLRALDAGASGIWVTNHGG
                     RQLDGGPAAFDSLQEVAEAVDQKVPIVFDSGIRRGQHIFKALASGADLVALGRPAIYG
                     LAMGGSTGTRQVFEKLNDELKMVMQLAGTQTIQDVKAFNLRHNPYDSSIPFDQNALRL
                     D"
     gene            77247..82184
                     /gene="scpC"
                     /locus_tag="VB649_000215"
     CDS             77247..82184
                     /gene="scpC"
                     /locus_tag="VB649_000215"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CXC chemokine-degrading serine protease SpyCEP"
                     /protein_id="HEP1669201.1"
                     /translation="MEKKQRFSLRKYKSGTFSVLIGSVFLMMTTTVAADELTTTSEPT
                     ITNHAQQQAQHLTNTELSSAESQSPDTSQITLKTNREKEQSQGLVSEPTTTELADTDA
                     APMADTGPDATQKSASLPPVNTDVHDWVKTKGAWDKGYKGQGKVVAVIDTGIDPAHQS
                     MRISDVSTAKVKSKEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFGDFD
                     EDWENFEFDAEPKAIKKHKIYRPQSTQAPKETVIKTEETDGSHDIDWTQTDDETKYES
                     HGMHVTGIVAGNSKEAAATGERFLGIAPEAQVMFMRVFANDVMGSAESLFIKAIEDAV
                     ALGADVINLSLGTANGAQLSGSKPLMEAIEKAKKAGVSVVVAAGNERVYGSDHDDPLA
                     TNPDYGLVGSPSTGRTPTSVAAINSKWVIQRLMTVKELENRADLNHGKAIYSESVDFK
                     DIKDSLGYDKSHQFAYVKESTDAGYKAQDVKGKIALIERDPNKTYDEMIALAKKHGAL
                     GVLIFNNKPGQSNRSMRLTANGMGIPSAFISHEFGKAMSQLNGNGTGSLEFDSVVSKA
                     PSQKGNEMNHFSNWGLTSDGYLKPDITAPGGDIYSTYNDNHYGSQTGTSMASPQIAGA
                     SLLVKQYLEKTQPNLPKEKIADIVKNLLMSNAQIHVNPETKTTTSPRQQGAGLLNIDG
                     AVTSGLYVTGKDNYGSISLGNITDTMTFDVTVHNLSNKAKTLRYDTELLTDHVDPQKG
                     RFTLTSRSLKTYQGGEVTVPANGKVTVRVTMDVSQFTKELTKQMPNGYYLEGFVRFRD
                     SQDDQLNRVNIPFVGFKGQFENLAVAEESIYRLKSQGKTGFYFDESGPKDDIYVGKHF
                     TGLVTLGSETNVSTKTISDNGLHTLGTFKNADGKFILEKNAQGNPVLAISPNGDNNQD
                     FAAFKGVFLRKYQGLKASVYHASDKEHKNPLWVSPESFKGDKNFNSDIRFAKSTTLLG
                     TAFSGKSLTGAELPDGYYHYVVSYYPDVVGAKRQEMTFDMILDRQKPVLSQATFDPET
                     NRFKPEPLKDRGLAGVRKDSVFYLERKDNKPYTVTINDSYKYVSVEDNKTFVERQADG
                     SFILPLDKAKLGDFYYMVEDFAGNVAIAKLGDHLPQTLGKTPIKLKLTDGNYQTKETL
                     KDNLEMTQSDTGLVTNQAQLAVVHRNQPQSQLTKMNQDFFISPNEDGNKDFVAFKGLK
                     NNVYNDLTVNVYAKDDHQKQTPIWSSQAGASASAIESTAWYGITARGSKVMPGDYQYV
                     VTYRDEHGKEHQKQYTISVNDKKPMITQGRFDTINGVDHFTPDKTKALGSSGIVREEV
                     FYLAKKNGRKFDVTEGKDGITVSDNKVYIPKNPDGSYTISKRDGVTLSDYYYLVEDRA
                     GNVSFATLRDLKAVGKDKAVVNFGLDLPVPEDKQIVNFTYLVRDADGKPIENLEYYNN
                     SGNSLILPYGKYTVELLTYDTNAAKLESDKIVSFTLSADNNFQQVTFKMTMLTTSQIT
                     AHFDHLLPEGSRVSLKTAQGQLIPLEQSLYVPKAYGKTVQEGTYEVVVSLPKGYRIEG
                     NTKVNALPNEVHELSLRLVKVGDASDSTGDHKVMSKNNSQALTASATPTKTTTSATAK
                     ALPSTGEKMGLKLRIVGLVLLGLTCVFSRKKSTKD"
     gene            82956..83663
                     /locus_tag="VB649_000216"
     CDS             82956..83663
                     /locus_tag="VB649_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEP1669202.1"
                     /translation="MSKKKRKHYQVYEGLRCAMTLCFISGYVNAFTYMTQGKRFAGVQ
                     TGNLLSFAIRLSEQQLKEALQFLLPMIVFMLGQSFTYFMHRWATKKGLHWYLLSSVML
                     TGLAFGTALFTPFLPSNVTVAALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYEKNHELTHIGRNTLIVILAFAVGVVCSTLLCIAYGEYALMPILMPLLYVNYLL
                     AQEFYHIQTKIKPIKRT"
     gene            83903..85903
                     /gene="metG"
                     /locus_tag="VB649_000217"
     CDS             83903..85903
                     /gene="metG"
                     /locus_tag="VB649_000217"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEP1669203.1"
                     /translation="MMKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIQTKAKEAGITPQTYVDNMAKDVKALWQLLDISYDTFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLKEVFRDEDGQVIGGIAPSGH
                     EVEWVSEESYFLRLSKYADRLVAFFKERPDFIQPDGRMNEMVKNFIEPGLEDLAVSRT
                     TFTWGVPVPSDPKHVVYVWIDALLNYATALGYGQANHANFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDLPMPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGTVPAYVDNGT
                     AFDADLSQLIDAQLADYHKHMEAVDYPRALEAIWTIIARTNKYIDETAPWVLAKEDGD
                     KAQLASVMAHLAASLRVVAHVIQPFMMETSAAIMAQLGLAPVSDLSTLALADFPANTK
                     VVAKGTPIFPRLDMEAEIDYIKAQMGDSSAISQEKEWIPEEVALKSEKDVITFETFDA
                     VEIRVAEVKEVSKVEGSEKLLRFRVDAGDGQDRQILSGIAKFYPNEQELVGKKLQIVA
                     NLKPRKMMKKYISQGMILSAEHGDQLTVLTVDSSIPNGSIIG"
     gene            86399..87412
                     /gene="nrdF"
                     /locus_tag="VB649_000218"
     CDS             86399..87412
                     /gene="nrdF"
                     /locus_tag="VB649_000218"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEP1669204.1"
                     /translation="MTQHYYERSQSPIEYALSETQKQLRSINWNYLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQQLITRTYTGLTLLDTVQATVGDVAQIQHSQT
                     DHEQVIYTNFAFMVGIHARSYGTIFSTLCSSEQIEEAHEWVVSTQSLQDRARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVARLSPEKQAEMKAFVFDLLYELIDLEKAYLRELYAGFDLAEDAIRFSLYNA
                     GKFLQNLGYESPFTDEETRVSPEVFAQLSARADENHDFFSGNGSSYVMGITEETTDDD
                     WEF"
     gene            87416..87904
                     /gene="nrdI"
                     /locus_tag="VB649_000219"
     CDS             87416..87904
                     /gene="nrdI"
                     /locus_tag="VB649_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEP1669205.1"
                     /translation="MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYL
                     LIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQ
                     KLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHT
                     SH"
     gene            87871..90051
                     /gene="nrdE"
                     /locus_tag="VB649_000220"
     CDS             87871..90051
                     /gene="nrdE"
                     /locus_tag="VB649_000220"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEP1669206.1"
                     /translation="MSQTNASYLSLNALTRFKKTDGSYHFDSDKEAVRRYLEEHVSPN
                     QMAFNSLEDKLAYLINEGYYEQAIFDAYPNDLIKEAFHYAYQQGYRFLNLMGAMKFYQ
                     SYALKTLDGKHYLETFEDRAVMNALFLADGDQTFVFDVIDAILHRRFQPATPTFLNAG
                     KKRRGEYISCYLLRVEDNMESISRAISTSLQLSKRGGGVALCLTNLREIGAPIKGIEN
                     QATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIK
                     SLALGLVIPDITFQLAKENKDMALFSPYDIKRAYGKDMSDISITEEYDKLLANPAIKK
                     TYISARKFFQLIAELHFESGYPYLLFDDTVNKRNPHAKKGRIVMSNLCSEIAQVSTPS
                     TFKEDLSFETIGEDICCNLGSINIAQAMADAPHFEQLITTSIRALDRVSRVSDLNCAP
                     SVETGNAANHAVGLGAMNLHGFLATNHIYYDTKEAVDFTDLFFHAMAYYAFKASCQLA
                     KEKGAFAGFSLSTYADGTYFAKYLQEDAKPQTAKVATLLQDYGFTLPTVADWQSLVAD
                     IKQFGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGSLGRIYVPAYQIDQA
                     NYAYYERGAYEVGPKAIIDVVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKQN
                     CASIYYVRVRQDVLAGSEQYDEDSLVTAPGASDETTTECQSCMI"
     gene            complement(90258..91010)
                     /locus_tag="VB649_000221"
     CDS             complement(90258..91010)
                     /locus_tag="VB649_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEP1669207.1"
                     /translation="MLKKRYQLAIVLLLSCFSLIWQTEGLVELFVCEHYERAVCEGTP
                     AYFTFSDQKVAETLIKKRWGKGLVYPRAEQEAMAAYTCQQAGPINTSLDKAKGELSQL
                     TPELRDQVAQLDAATHRLVIPWNIVVYRYVYETFLRDIGVSHADLTSYYRNHQFDPHI
                     LCKIKLGTRYTKHSFMSTTALKNGAMTHRPVEVRICVKKGAKAAFVEPYSAVPSEVEL
                     LFPRGCQLEVVGAYVSQDQKKLHIEAYFKGSL"
     gene            91468..91938
                     /locus_tag="VB649_000222"
     CDS             91468..91938
                     /locus_tag="VB649_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669208.1"
                     /translation="MKTKSKRFLNLATLCLALLSTTLLTTQPVKAEIALAEGESTSHQ
                     TAQPISQSKLFLGSESGENSTYGHDVWRGLGHSDGYEKGKESDSPDIGDIDVPNYVSD
                     KEAYKEGYQEGFEEGRREARPIETVLETVWQFLTDIFTDIFDGWFGSNNSSQSQ"
     gene            92434..92924
                     /locus_tag="VB649_000223"
                     /pseudo
     CDS             92434..92924
                     /locus_tag="VB649_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407355.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            93167..93610
                     /locus_tag="VB649_000224"
     CDS             93167..93610
                     /locus_tag="VB649_000224"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669209.1"
                     /translation="MRTKSNYFLNLATLCLALFGAILLMAQPANAEEVSPNIGVEGTS
                     TRQYYGEMQEEYDEEAELSSKDREFGRQNGQKDGKEGKNGFGPTINRNDIQVPEKVKH
                     QDEYQDGYEQGYREGWQQEHPLLGVVFDVFDLIWGAVGGFFSLAN"
     gene            93844..94095
                     /locus_tag="VB649_000225"
     CDS             93844..94095
                     /locus_tag="VB649_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669210.1"
                     /translation="MPEKKVLPVLSMMMSFVCLLDHIFFFATYSYLYLPLVASSLALI
                     GLVQNKGRQKVWSLVGLILAALAVAVVTYAYYDPTVIPY"
     gene            complement(94189..94860)
                     /locus_tag="VB649_000226"
     CDS             complement(94189..94860)
                     /locus_tag="VB649_000226"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669211.1"
                     /translation="MKKTLTLLLALFAIGVTSSVRADSRYDSNSNLGKGYYGDDDYTM
                     PPLSTGDPKKIGFRTDWCESQSFGIKPINIGDSEVEVKTEPHAIIIASLNSEPAVFGR
                     ADSSGKAKLNLQKKENRNPPKVTTVYGDKVRITIKDSEGFGIGSETWIIGKSKPKDQI
                     EKEEEKYEKEIAEILEELELQEQEREALDLFKNAANDRSNKPWHQRLSESIQDQWWNF
                     KGLFQ"
     gene            95221..95457
                     /locus_tag="VB649_000227"
     CDS             95221..95457
                     /locus_tag="VB649_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEP1669212.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTLEVDGKVLQAT
                     PYFLIHVTGAGEGFSMWAPTPCDVLAEDWIEVND"
     gene            95450..96148
                     /locus_tag="VB649_000228"
     CDS             95450..96148
                     /locus_tag="VB649_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEP1669213.1"
                     /translation="MTKVVLVTGCASGIGYAQARYFLRQGHHVYGVDKSDKPDLNGNF
                     HFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVK
                     LTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
                     HIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTKPDEVAELTGFLASGKARSM
                     QGEIVKIDGGWTLK"
     gene            96224..97183
                     /locus_tag="VB649_000229"
     CDS             96224..97183
                     /locus_tag="VB649_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEP1669214.1"
                     /translation="MKLAVLGTGMIVKEVLPVLQKIDGIDLVAILSTVRSLTTAKDLA
                     KAYHMPLVTSKYEAVLGNEEIDTVYIGLPNHLHFAYAKKALLAGKHVICEKPFTMTAG
                     ELDELVVIAKKRKLILLEAITNQYLSNMTFIKEHLDQLGDIKIVECNYSQYSSRYDAF
                     KRGDIAPAFNPKMGGGALRDLNIYNIHFVVGLFGRPKTVQYLANMDKGIDTSGMLVMD
                     YEQFKVVCIGAKDCTAEIKSTIQGNKGSLAVLGATNTLPQVQLSLHGHEAQVINHNKH
                     DHRMYEEFVAFRDMIDQKDYDKANLALEHSRAVMAVLERAVHS"
     gene            97516..98853
                     /locus_tag="VB649_000230"
     CDS             97516..98853
                     /locus_tag="VB649_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP1669215.1"
                     /translation="MEEDYNKREPEKFTQFLRRQKVVFFVAFFGYVCAYLVRNNFKLM
                     SNTIMVQNGWDKAQIATLLSCLTVSYGLAKFYMGALGDRVSLRKLFSISLGASALICI
                     LIGFFNSSMVVLGILLVLCGVVQGALAPASQAMIANYFPNKTRGGAIAGWNISQNMGS
                     ALLPLTIALLTSMGLVVPANGNILLAFLIPGVLVFLFALCCWKLGGDNPESEGLDSLR
                     TMYGDAGESAVASEEEKHNLSYWQLIWKYVFCNPSLLLVAAVNVALYFVRFGIEDWMP
                     IYLSQVANMSEAHIHFAISMLEWVAIPGSLVFAWLAVRYPNKMAKIGAIGLFVLAAIV
                     FVYERLTAAGAPNYFLLLVISGILGALIYGPQLIVNILTINFVPLNVAGTAIGFVGVT
                     AYLIGNMGANWLMPILADGFGWFWSYIVVAALSAFSAVGYLILAKREEEIIKD"
     gene            99026..100408
                     /gene="glmU"
                     /locus_tag="VB649_000231"
     CDS             99026..100408
                     /gene="glmU"
                     /locus_tag="VB649_000231"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEP1669216.1"
                     /translation="MTNYAIILAAGKGTRMTSDLPKVLHKVSGLTMLEHVFRSVKAIS
                     PEKSVTVIGHKSEKVRAVLADQSAFVHQTEQLGTGHAVMMAETQLEGLEGHTLVIAGD
                     TPLITGESLESLIDFHVNHKNVATILTATAQDPFGYGRIVRNKDGEVIKIVEQKDANE
                     YEQQLKEINTGTYVFDNKRLFEALKCITTNNAQGEYYLTDVVAIFRANKEKVGAYILR
                     DFNESLGVNDRVALATAEIVMRQRITQKHMVNGVTFQNPETVYIESDVEIAPDVLIEG
                     NVTLKGRTHIGSGTVLTNGTYIVDSEIGQGSIITNSMIESSVLAAGVTVGPYAHLRPG
                     TTLDREVHIGNFVEVKGSHIGEKTKAGHLTYIGNAQVGSSVNVGAGTITVNYDGQNKY
                     ETVIGDHAFIGSNSTLIAPLEVGDNALTAAGSTISKTVPADSIVIGRSRQVTKEGYAK
                     RLAHHPSRSK"
     gene            100439..100993
                     /locus_tag="VB649_000232"
     CDS             100439..100993
                     /locus_tag="VB649_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP1669217.1"
                     /translation="MKFEEKTLKRQTVFDGHIFKVVVDDVELPNNLGQSKRELIFHRG
                     AVAVLAITPERKIVLVKQYRKAIESVSYEIPAGKLEIGEEGSKLKAAARELEEETAYT
                     GTLTFLYEFYTAIGFCNEKITLFLATDLTQVANPKPQDDDEVIEVLELTYQECMDLVA
                     QGKLADAKTLIALQYYALHFGGEQ"
     gene            100993..101244
                     /locus_tag="VB649_000233"
     CDS             100993..101244
                     /locus_tag="VB649_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669218.1"
                     /translation="MGRPLLTDDIIEKARRMETFEPDDAVDFDTKVMTLPEKDDKARI
                     YKSRRIENAKRSQLQSKLNVILIAVMLLIAILVYAIFYL"
     gene            101264..101959
                     /locus_tag="VB649_000234"
     CDS             101264..101959
                     /locus_tag="VB649_000234"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEP1669219.1"
                     /translation="MKIGIIAAMEEELSLLLANLLDAQEHQVLSKTYYTGRFGKHELI
                     LVQSGVGKVMSAMTVAILVEHFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDA
                     TAFGYAYGQMAGQPLYYDCDPQFVAIFKQVLKHEKTNGQVGLIATGDSFVAGQDKIDQ
                     IKTAFSDVLAVEMEGAAIAQAAHTAGKPFIVVRAMSDTAAHDANITFDQFIIEAGKRS
                     AQTLMTFLENLPV"
     gene            102110..102451
                     /locus_tag="VB649_000235"
     CDS             102110..102451
                     /locus_tag="VB649_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669220.1"
                     /translation="MTLKKHYYLLSLLALVTVGAAFNTSQSVSAQVYSNGGYHQHLTD
                     QKSHLQYSKDNAQLQLRNILNGYQSDLGKHYSSYYYYNLRTVMGLSSKQKIEEHYEKL
                     KDELYRMYNHY"
     gene            complement(102550..103197)
                     /locus_tag="VB649_000236"
     CDS             complement(102550..103197)
                     /locus_tag="VB649_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEP1669221.1"
                     /translation="MTPNKEDYLKCIYEIGEQETKITNKMVAEKMHVSAPAVSEMIKK
                     MISQGWIVKDKAKGYLLKDKGYALVANLYRKHRLIEVFLIHQLGYNTQEVHQEAEVLE
                     HTVSDTFIDRLDKVLDFPDFCPHGGTIPRYGQPLVEMNTTTLNTITELGRFRLSRIHD
                     HFDLIQYLEAHHLNINTELTLTQIDTFAKTYTICYDDKDLIIPENIAKQLYVTAL"
     gene            103343..104275
                     /locus_tag="VB649_000237"
     CDS             103343..104275
                     /locus_tag="VB649_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_101244918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEP1669222.1"
                     /translation="MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIA
                     DMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADVIFYNGINLEDGGQAWFT
                     KLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
                     AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYS
                     EIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK"
     gene            104339..105064
                     /locus_tag="VB649_000238"
     CDS             104339..105064
                     /locus_tag="VB649_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEP1669223.1"
                     /translation="MITTNNLCVTYDGNSNALEAINVTIEGPSIVGIIGPNGAGKSTF
                     MKAILNLIDYQGHVTVDGKDGRKLGHTVAYVEQRSMIDYNFPITVKECVALGTYSKLG
                     LFRRVGKKQFEQVDKVLKQVGLEDFGHRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIVDLLKELKMAGKTILIVHHDLSKVEHYFDKLMILNKHLVAYGKVN
                     DIFTVDTLSKAYGNHLILGKEMV"
     gene            105065..105919
                     /locus_tag="VB649_000239"
     CDS             105065..105919
                     /locus_tag="VB649_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEP1669224.1"
                     /translation="MSMKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGVNFFIGAIIFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDSDKWITIGVSIFVLGVISLFFKELLLT
                     SFDPILAKSMGVKVNAYHYLLMVLLTLVAVTAMQSVGTILIVALLITPAATAYLYANS
                     LKVMLVMSSLLGALASVLGLYLGYTFNVAAGSSIVLTSAMMFLISFFVSPKQGYLKRW
                     MQKKEKTP"
     gene            complement(106066..106872)
                     /locus_tag="VB649_000240"
     CDS             complement(106066..106872)
                     /locus_tag="VB649_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEP1669225.1"
                     /translation="MKKLLSLSLVAISLLSLSACESVDRAIKGDKYIDEKTAKEESEA
                     ASKAYEESIQKALKADASQFPQLTKEVGKEEAKVVMRTSQGDITLKLFPKYAPLAVEN
                     FLTHAKKGYYDNLTFHRVINDFMIQSGDPKGDGTGGESIWKGKDPKKDAGNGFVNEIS
                     PFLYHIRGALAMANAGANTNGSQFYINQNKKNQSKGLSSTNYPKPIISAYEHGGNPSL
                     DGGYTVFGQVIDGMDVVDKIAATSINQNDKPEQDITITSIDIVKDYRFKN"
     gene            107089..109494
                     /locus_tag="VB649_000241"
     CDS             107089..109494
                     /locus_tag="VB649_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEP1669226.1"
                     /translation="MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAM
                     LRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLV
                     EWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQA
                     EKEALEKQAQEEEKRLAELTVDPETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLK
                     DDETSLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVDFTPKTHLVYKLPTI
                     DLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGV
                     RVNRISNLADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANP
                     ENLLEVPLGKAVNGNARSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQVK
                     FMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKIGVRNIA
                     GYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIH
                     MILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPI
                     DENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFDPGEVSDNDPGFSGNGGAAEG
                     DPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVL
                     QTN"
     gene            complement(109564..109917)
                     /locus_tag="VB649_000242"
     CDS             complement(109564..109917)
                     /locus_tag="VB649_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEP1669227.1"
                     /translation="MMIYKLTALAFLIVTPLFAMIVTSLFKLNKKGFKFPDVALLLFA
                     IEIVLVSGKFFTHNLLPYYLIIMSLLAIVISLLLVIRTQSFSYHRFMKLFWRVGFLVT
                     VIFYLILVIFIFTLA"
     gene            110161..110586
                     /gene="rplK"
                     /locus_tag="VB649_000243"
     CDS             110161..110586
                     /gene="rplK"
                     /locus_tag="VB649_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEP1669228.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNTTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            110692..111381
                     /gene="rplA"
                     /locus_tag="VB649_000244"
     CDS             110692..111381
                     /gene="rplA"
                     /locus_tag="VB649_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEP1669229.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQ
                     GVGIKVDPNSL"
     gene            111703..112431
                     /locus_tag="VB649_000245"
     CDS             111703..112431
                     /locus_tag="VB649_000245"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEP1669230.1"
                     /translation="MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSG
                     VQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIQRVVFGEHIGTTVSNKVCD"
     gene            112460..113017
                     /gene="frr"
                     /locus_tag="VB649_000246"
     CDS             112460..113017
                     /gene="frr"
                     /locus_tag="VB649_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEP1669231.1"
                     /translation="MANAIIETAKERFAQSHHSLSREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDI
                     QKATDDAIKEIDRMTAEKEKELLSV"
     gene            113126..113983
                     /locus_tag="VB649_000247"
     CDS             113126..113983
                     /locus_tag="VB649_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEP1669232.1"
                     /translation="MNDLLATVITGLIKEENANDYFIQKEGFTFTLSKAEGERQIGDM
                     VTGFAYIDIKQKARLTTKEIRSTRTSYGWGEVTEVRRDLGVFVDTGIPNKEIVVSLDV
                     LPEMKELWPKKGDKLYIRLDVDKKDRIWGLPAESEVFQKMASPAYNNMQNQHWPAIVY
                     RLKLTGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMIVTYLEANGGFMTLNDKSSPEEIKATFGISKGQFKKALGGLMKAKRIKQ
                     DATGTELIG"
     gene            114056..114565
                     /gene="msrA"
                     /locus_tag="VB649_000248"
     CDS             114056..114565
                     /gene="msrA"
                     /locus_tag="VB649_000248"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEP1669233.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQV
                     CAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTE
                     RQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIR
                     HQFLEENWS"
     gene            114562..114777
                     /locus_tag="VB649_000249"
     CDS             114562..114777
                     /locus_tag="VB649_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEP1669234.1"
                     /translation="MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELI
                     SRYLEDQASFSFNLGQFDEIWEDYLAH"
     gene            114933..116102
                     /locus_tag="VB649_000250"
     CDS             114933..116102
                     /locus_tag="VB649_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEP1669235.1"
                     /translation="MIITKKSLFVTSVALSLAPLATAQAQEWTPRSVTEIKSELVLVD
                     NVFTYTVKYGDTLSTIAEAMGIDVHVLGDINHIANIDLIFPDTILTANYNQHGQATAL
                     TVQAPASSPASVSHVPSSEPLPQASATSQSTVPMAPSATPSDVPTTPFASAKPDSSVT
                     ASSELTSSTNDVSTESSSESQKQPEVPQEAVPTPKAVETTEVEPKTDISEGPTSANRP
                     VPNESASEEVSSAAPAQAPAEKEETSAPAAQKAVADTTSVATSNGLSYAPNHAYNPMN
                     AGLQPQTAAFKEEVASAFGITSFSGYRPGDPGDHGKGLAIDFMVPENSALGDQVAQYA
                     IDHMAERGISYVIWKQRFYAPFASIYGPAYTWNPMPDRGSITENHYDHVHVSFNA"
     gene            116416..118188
                     /locus_tag="VB649_000251"
     CDS             116416..118188
                     /locus_tag="VB649_000251"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HEP1669236.1"
                     /translation="MYYTSGNYEAFATPRKPEGVDQKSAYIVGTGLAGLAAAVFLIRD
                     GHMAGERIHLFEELPLAGGSLDGIEKPHLGFVTRGGREMENHFECMWDMYRSIPSLEI
                     PGASYLDEFYWLDKDDPNSSNCRLIHKRGNRVDDDGQYTLGKQSKELIHLIMKTEESL
                     GDQTIEEFFSEDFFKSNFWVYWATMFAFEKWHSAVEMRRYAMRFIHHIDGLPDFTSLK
                     FNKYNQYDSMVKPIIAYLESHDVDIQFDTKVTDIQVEQTAGKKVAKTIHMTVSGEAKA
                     IELIPDDLVFVTNGSITESSTYGSHHEVAKPTKALGGSWNLWENLAAQSDDFGHPKVF
                     YQDLPAESWFVSATATIKHPAIEPYIERLTHRDLHDGKVNTGGIITITDSNWMMSFAI
                     HRQPHFKEQKENETTVWIYGLYSNSEGNYVHKKIEECTGQEITEEWLYHLGVPVDKIK
                     DLASQDYINTVPVYMPYITSYFMPRVKGDRPKVIPDGSVNLAFIGNFAESPSRDTVFT
                     TEYSIRTAMEAVYSFLNVERGIPEVFNSAYDIRELLKAFYYLNDKKAIKDMDLPIPAL
                     IEKIGHKKIKDTFIEELLKDANLM"
     gene            118347..119399
                     /locus_tag="VB649_000252"
     CDS             118347..119399
                     /locus_tag="VB649_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEP1669237.1"
                     /translation="MQEYSIDITLTHPDDVLALFGSNERHLKLIEAHLGVIVHARTER
                     VQVIGDDEEAVELARLTIKALLVLVGRGMVVNTSDVVTALSMAESHQIDQFMALYEEE
                     IIKDNYGKAIRVKTLGQKTYVDSVKRHDVVFGVGPAGTGKTFLAVTLAVTALKRGQVK
                     RIILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYHILGKEQTTRLMERDVIEIA
                     PLAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDTSQIDLPRNVKS
                     GLIDATQKLQGIKQIDFVYFSAKDVVRHPVVADIIKAYETSSEEMKDLLKPKASDVEA
                     DYQPGLTKYPVIGQEH"
     gene            119445..120020
                     /locus_tag="VB649_000253"
     CDS             119445..120020
                     /locus_tag="VB649_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEP1669238.1"
                     /translation="MDDLTKAIMADEANLSYTERGIFPLYDAPQTARIIIVGQAPGIV
                     AQETKLYWNDRSGIRLRDWLGVDNDTFYHSGLFGIIPMDFYYPGKGKSGDLPPREGFA
                     AKWHPPLRALMPEVELTILVGRYAQDFYLGNKAYKTLTETVRHFEDYLPDYFPLVHPS
                     PRNQLWLAKNPWFEQDLLPILQKRVEAILTK"
     gene            120179..120676
                     /gene="ybeY"
                     /locus_tag="VB649_000254"
     CDS             120179..120676
                     /gene="ybeY"
                     /locus_tag="VB649_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEP1669239.1"
                     /translation="MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGEL
                     FISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            120657..121064
                     /locus_tag="VB649_000255"
     CDS             120657..121064
                     /locus_tag="VB649_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEP1669240.1"
                     /translation="MALHDNNTTKRKWKNRTITSSLEFALTGVFTAFKEERNLRSHLL
                     SACLACVAGLFFSISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKNA
                     KDMAAGAVLMISGYAVLTGLIIFIPKIWNIFVH"
     gene            121184..122080
                     /gene="era"
                     /locus_tag="VB649_000256"
     CDS             121184..122080
                     /gene="era"
                     /locus_tag="VB649_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEP1669241.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTL
                     IKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKR
                     DEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNEKEY"
     gene            122100..122576
                     /locus_tag="VB649_000257"
     CDS             122100..122576
                     /locus_tag="VB649_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEP1669242.1"
                     /translation="MPQDYITYIRSKVGHDKIILNFAGGILINDDGKVLMQLRGDKKT
                     WAIPGGTMELGESSLETCKREFLEETGIEVEAVRLLNVYTHFEEVYPNGDAVQTIVFI
                     YELTAVSDMAIDNFHNEETLKLQFFSHEEIAELESVSAKHRLMLEEYFSDSFAMGH"
     gene            123279..123680
                     /locus_tag="VB649_000258"
                     /pseudo
     CDS             123279..123680
                     /locus_tag="VB649_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638212.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
     gene            complement(123738..124184)
                     /locus_tag="VB649_000259"
     CDS             complement(123738..124184)
                     /locus_tag="VB649_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP1669243.1"
                     /translation="MSYKYGFGRDTLSDISLTIKEGEKVSIVGISGSGKTTLAKMIVN
                     FFEPYKGQISINHQNLKMIDKKVLRQHINYLPQQAHIFSGSILENLTLGANHSTSQED
                     ILINIRNDIHILKFDTYFQTGQNIKKEKRIKRKIFHSYFIYIYFSM"
     gene            complement(124407..125117)
                     /locus_tag="VB649_000260"
     CDS             complement(124407..125117)
                     /locus_tag="VB649_000260"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669244.1"
                     /translation="MSFLPLIFKQESLIFYIVLASLLVTLINIGGSYYLQGIWDEYIP
                     NQMKPTLGIISIGLIVTYILQQMMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSF
                     FVTRRTGEIISRFTDANAIIDTLASTILSLFLDVSILSIVGGVLLVQNTNLFLLSLIS
                     IPIYIIIIFTFMKPFEKMNNNVMQSNSMASSAIIEDINGIETIKSLTSEEIRYQKIDS
                     EFVDYLDKSFKLSKYSTK"
     gene            complement(125222..125458)
                     /locus_tag="VB649_000261"
     CDS             complement(125222..125458)
                     /locus_tag="VB649_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669245.1"
                     /translation="MTSCKRTFVPQIDARDCGIAALASIAKFYGSDYSLTHLRELAKT
                     NKEGTTTLGIVKAAKEMGFEKNISSLEIQIPPLK"
     gene            125756..125980
                     /locus_tag="VB649_000262"
     CDS             125756..125980
                     /locus_tag="VB649_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEP1669246.1"
                     /translation="MNTTIKQFEIMDEAMLTGIEGGCSWHGLAQAAVFTGAGNGFRLG
                     VKTRTWQGAAAGAAGGLVIGGVGYGATCWW"
     gene            125958..126134
                     /locus_tag="VB649_000263"
     CDS             125958..126134
                     /locus_tag="VB649_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669247.1"
                     /translation="MGRLVGGNNHGYQKFFAWFSYWFTLPNFRQYIIEYPEKLEKPIE
                     DTKMGLYSVYIGDL"
     gene            126491..126739
                     /locus_tag="VB649_000264"
     CDS             126491..126739
                     /locus_tag="VB649_000264"
                     /inference="COORDINATES: protein motif:HMM:NF014566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEP1669248.1"
                     /translation="MEEILFRGILQEKLSRVSFWLSIIVTSVIFSYIHGNDTILNTQF
                     ISSLIYGMAYQTSKDLRFPIINHSLQNLIVLLTVVLLK"
     gene            127350..127577
                     /locus_tag="VB649_000265"
     CDS             127350..127577
                     /locus_tag="VB649_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEP1669249.1"
                     /translation="MNTKTMEQFEVMNSEMLAGVEGGWGGWGEAIAGLLGGFAPSPTL
                     DQLNGKWPIRKPSKPCRPYGTGGTPNACNGL"
     gene            127626..127943
                     /locus_tag="VB649_000266"
     CDS             127626..127943
                     /locus_tag="VB649_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="role in replication"
                     /protein_id="HEP1669250.1"
                     /translation="MLTLYKRQIAEVWEIGRETPQPEWVRDAFRKNYICWLDEHVRIL
                     MTGLNPSLTTNLKIGATGTVGGGFAGYGMYVLGYPGDFLDVTNHRVISAKKFHKEYQI
                     IDG"
     gene            128009..128290
                     /locus_tag="VB649_000267"
     CDS             128009..128290
                     /locus_tag="VB649_000267"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP1669251.1"
                     /translation="MEDCRKYFLCRFSFIHHLFGTKIISSTLKIHPNSLYRWIQEYEK
                     YGESAFPGHGSALRHAQFETKKLEKEHKLLQEELALLKKFQVFLKPNRK"
     gene            128424..128618
                     /locus_tag="VB649_000268"
     CDS             128424..128618
                     /locus_tag="VB649_000268"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP1669252.1"
                     /translation="MKEMIKAIFYEHKERYGSVRITQELCRRGIHVNYKRVGRLLHQL
                     GLYAKGSRYQYKYYNRRRSS"
BASE COUNT        40617 a        22988 c        26913 g        38123 t
ORIGIN      
        1 aaaaagtgta atcatttttt gatttacagt tattatcatg tgttatctgg cgactgtcct
       61 gtttacaagt aagttcacaa gtatgggata aaatagtata aactatagta aatactgaat
      121 agtcaaagaa aaatatcggc ataggtcaga agagctgata tgtttaatac tttttgcgga
      181 tatctactgt atttaaatgt atttgatatc cttgtcaagg atatacgtct aaacaagttc
      241 aaaacgaaat catttgtgat tatcttatca ggagttgact cttgataaga tttttgtata
      301 tcagtactgt ggtacgttta gatagtttgg cagtgaattt atagagtgtc aaacaacgag
      361 tgttttgtgt tacactaacc attagaagag tctatttttg agcatatcaa ggtgttatct
      421 tttcgagttg aggtatcata tctagttgta atgtcaaaca tatctagtat atttaactag
      481 aactattccc gttgttgttt atcccaatta tgataagggt ttgctgaaca gtaaaaagaa
      541 aaatcgccac gataaagtag cgatttttct cttttatgag cctcaaaaaa cgtcaaagcg
      601 ttataatagt tagtgcaaat atctctatta acgaggtctc actatgcaca ttataacaca
      661 actcaatctc tttgaagacc aagaactagg agatttggaa aaaattttga tggttttgga
      721 tggtcttcct gaaacagatt tattccaacg cttagaagcg aaacgtaaac acggtcgcag
      781 ggattactct gtccaatcct actttatcgc cagtatcgct aaacgcattc ttcagcttga
      841 aaccgaccag cagttgctca gacagttacg gatgaacagt caattgcgtc aaatctgtgg
      901 ttttgaaact catggtgttc gcttgaattc tggtgtgaca aaacttgtga gtgtgccgtc
      961 taaatcagcc tactctcgct ttatgcaaga cctgcaagag gtatgtccgg atattgagga
     1021 ctggattcaa gcaggtgttg aggagcttta cgacttactc cctgattttg gaagggtgct
     1081 tgccctggac gggaaaatta tagaaactta ctgcgacacc ttacggcaaa aagaagaaag
     1141 gggatagacg ctctgattta gatgcggatt tcaccaagaa ggaaaagcgc cataaggacg
     1201 gcacagtgac tattgagcgt tattatggct atagagctca tcttatcgtt gacagtactt
     1261 atgagctgtc tattctttgg gaagtcacgc ctgtttctca tggtgagcca accgtcgcca
     1321 agcgtatggt caagaatttc agtgctaaaa cacttgacca agcacagtat ctaacggcag
     1381 acagaggcta tagtggtgcg cctcttcaaa atctcttgga agatgccgac atcatcccca
     1441 tcatcgacaa tccacataaa tggaaagagg atgagacccg ccagtatctg gataccaatc
     1501 tcatttacaa ccagtcaggt gaggtttttt gggtggatga gaaaggcaaa gcagagaaac
     1561 tgatttacaa gggttatgac aagtcctgtg atagcttgcg ttatggtttt catcccggcc
     1621 aagatgatga ccgtattttt cgcttaaaac gacgtgtcga ccctattatt ttcaataagg
     1681 ttgctcgcga tagcgaaaag tttaaaaaat tgtacaaaaa acgcacagcc gttgaacgcg
     1741 tgaatggcag acttgaccga gattttcgtt tagaaaccca taccatacga ggacttaaga
     1801 agatgaacgt ggcagtcagt atgagttttt tggttatgat tggttttgcg ctgtcaaaac
     1861 tcaaagcagg acaaagagag cacttaggca gctgggtagt ttaaccgttc gaaaaaattg
     1921 ctgtaactac aaggaatttt tgcgcccttt tttgtgtatt ttcgaaaatc ttctgctttc
     1981 taagttagga agtagtagct tttttatgaa tgtagacttg ttttttgaaa tggcgcaaac
     2041 tccttaagtg aaatagtaac tacgggaatg attcaactat ggttttaaat gctatttcaa
     2101 aaaaaatatg ataaaataga aagtactaat tattttggag atgacatgag tatcgatgat
     2161 tataggccga cctatatggt agaggctatt tatgatttaa gagcaaatga tttgttgcgt
     2221 catggtatta cggctgtttt agtggattta gataatacct taattgcatg gaataatcct
     2281 gatggcacac cagaggttcg cgcttggctt gatgaaatga ctatcgcgga tattagcgtg
     2341 gttgttgttt caaataataa acattctcgt gttgagcgtg ccgtttcacg atttggtgtt
     2401 gactttatta gccgtgcttt gaagccattt gcttatggta ttgaaaaagc cattgctcgt
     2461 tatggatttg atcgcaacga ggttatcatg gttggagatc agctaatgac tgatatcaga
     2521 gctagtcata gagctggaat aaaatcagtt ttagtcaaac cacttgttgc ttctgatgct
     2581 tggaatacta aaattaaccg ctggcgtgaa cgccgtgtga tggcaaaatt agaagagaaa
     2641 tatggtaaat tatcatatca aaaaggaatt taatggaaga attattttgt ataggctgtg
     2701 gtatccagat tcaaactgaa gataaagaaa aagctggttt tacgccagct gctgctttga
     2761 aaaagggtat ggaaacagga gaactctatt gtcagcgctg ctttagattg aggcattata
     2821 atgaaattac agatgtccat attaccgatg atgaattttt aagacttctt cacgaagtgg
     2881 gtgatagtga tgctcttgtg gttaatgtga ttgatatttt tgactttaat ggttctatta
     2941 ttccaggtct atctcgcttt atttctggta atgatgtctt actggttggg aataaaaaag
     3001 atattttgcc aaagtctgtt aaggatggta aagttactca atggttgacg gaacgtgcac
     3061 acgaagaagg tcttcgccct ttagacgtta tgttaacgag cgctcaaaat aaatatgcga
     3121 ttaaagactt gattgagcgt atcaatgagt tacgtaatgg tcgagatgtt tatgttgtgg
     3181 gggtcactaa tgttggtaaa tcaaccttga ttaatgcgat tatccaagag attactggta
     3241 acaaggatgt catcacgacg tctcgttttc ctgggacaac tcttgacaaa attgaaattc
     3301 ctttggatga tgggacgttc atttttgata caccaggaat tattcatagg caccagatgg
     3361 ctcattattt atcccctaaa gagctaaaaa tagtgagtcc taagaaggaa atcaagccta
     3421 agacgtatca attaaaccca gaacaaactc tctttttagg tggtttgtct cgctttgact
     3481 ttatcaatgg ggagcgtcaa gggtttacag ctttttttga caatcaacta gaattacatc
     3541 gtacaaaatt agctggagca gatgcttttt atgataagca tgttggaact ttgttaactc
     3601 cgccaggtaa gaaagagttg acagcatttc ctaaattagt tcgtcatgaa tttacaattg
     3661 atcagaaaat ggatattgtt ttttctggtc taggatggat tcgtgttaat ggtcaaaaag
     3721 actcaaaagc aatagttgct gcatgggctc ctgaaggggt cgctgtcatt gttcgtaaag
     3781 cgattattta aaaataaaaa agaagttgga aaaaaatgct tacaagtaaa caaagagctt
     3841 tcttaaaatc tgaggctcat agcttaaaac cgattgtaca aattggcaaa aatggattaa
     3901 atgaccacat taagactagt attcgtcaag ctttggatgc tagagaattg ataaaggtca
     3961 ctttgttgca aaatactgat gaagatattc atgaagttgc agagatttta gaagaagaaa
     4021 ttgggtgtga tacggttttg aaaattggtc gtatcttgat tctctataag gtttctgcta
     4081 agaaagaaaa ccgcaagttg tcccctaaag ttaaagcaat ctagtccttt tatttgtata
     4141 ggggctggtc ttatgagacg aggactattg tcgcgagaat tttggagaaa gtatggcatt
     4201 agaattgttg acgcctttta cgaaggtgga attagaggaa gaaaaaaaag aaagcaaccg
     4261 caaacagatt gggattttag gaggaaattt taatcctatt cacaatgcac accttgtggt
     4321 tgcagatcaa gttcgccagc aattaggatt agatcaggtg ctattgatgc ctgaatgtaa
     4381 accaccgcat gtggatgcca aagagactat tgatgagaag catcgtcttt gcatgttgga
     4441 attggctatt gaagatgttg aagggctagc tattgaaacc tgtgaacttg aacgtcaggg
     4501 aattagctat acctatgata cgatgcttta tttgactgag cagcatcctg atgtcgatta
     4561 ttattttatt atcggagctg atatggttga ttatttgcca aagtggcacc gtattgatga
     4621 actggtcaaa cttgttcaat ttgttggggt tcaacgtcca aaatataaag ctggaacctc
     4681 ttacccagtc atttgggtag atcttccttt gatggatatt tcttctagta tgattaggga
     4741 ttttattaaa aaaggtcgtc agcccaatta tctcttacct aagcaggttt tagactacat
     4801 tactcaagaa ggtttgtatc aatgacatat gaagattatc ttccttatag caggaccgaa
     4861 ctgttagcaa aaattgcaga gcagatgagc cctaaacggt ttaaacatgt acttggcgtg
     4921 gaaaaggcag ccttgtcctt ggcagagtgt tatggttgta actcagacaa agcagggtta
     4981 gcagctcttt tacatgatta tgccaaggag tgccctgacc aggtcttttt agacttaatt
     5041 gacaagtacc aattatctcc agaattagct aaatggaata ataatgtctg gcatggtatg
     5101 gttggtattt ataagattca agaagaccta ggcctaaaag acaaagatat cttgcgagct
     5161 attaaaattc acaccgttgg tgctgctgag atgaccttgc tggataaggt cttatacgtt
     5221 gctgattata ttgaagaagg tcgcattttt cctttggttg atgacgctag aaaaatcgcg
     5281 aagctcgatt tgaatcaggc tgttgcctat gaaacagtga acactgtcgc ttatttagcc
     5341 tcaaaagcgc agcctatttt cccacaaact ctggatacct ataatgcgtt ttgcagctat
     5401 ttaaaggaat actaatggat aatgatatga ggaataaaat gaaaaaagaa gaactcttaa
     5461 aaattgttgt ggaagcaact gatgaaaagc gtgctaagga tattttagcc ttggatttag
     5521 aggggttaac tagtttgact gattattttg tgattgcgag tgcaacaaat agtcgtcaat
     5581 tagaggctat tgcggataat attcgtgaaa aggtaaaaga ggctggtgga gatgctagcc
     5641 atgttgaagg taatagccaa gcaggctggg tcttgcttga tttgaccgat gtggtggtac
     5701 atcttttttt agaagacgag cgttaccact ataatcttga aaaattgtgg catgaagcgc
     5761 ctgctgtggc tctagatgcc tatttagctt aatgttacaa agagaccttg tcaatacgac
     5821 agggtttttg aggatgataa tggaacataa ttatgaaaaa tttgcgtcag tttatgatgc
     5881 tgtgatggat gattctctat atgacttgtg gacagatttt tcacttcgac atttaccaaa
     5941 gtctaagggt cgaaatcgtt tgttagagtt ggcctgtgga accggtattc agtcagttcg
     6001 ttttgctcaa gcaggttttg atgtgactgg tttagactta agtcaaaaca tgctggctat
     6061 tgctaaaaag cgtgcgcaat ctgctaaaaa gaaaattgat tttattcaag gtaacatgct
     6121 ggatttgtca caggtggggc agtttgattt tgtaacctgc tattcggatt ccatttgcta
     6181 tatgcaagac gaagttgatg ttggcgatgt ttttaaagaa gtttatgatg ttttagcaaa
     6241 cgatggcatc tttatttttg atgtgcattc aacctatcaa acggatgagt gtttccctgg
     6301 ttattcctat catgagaatg cagatgattt tgcaatggtt tgggatacct atgctgacga
     6361 ggctcctcac tctgttgttc acgaactcac tttctttatc caagaagacg atggacgttt
     6421 ttctcgcttt gatgaagtgc atgaggaacg aacgtatgag ttattgactt atgatatttt
     6481 gttggaacaa gcagggttca agtcatttaa ggtctatgct gattttgaag ataaggagcc
     6541 aactaagacc agcaagcgtt ggttttttgt agcgcaaaag tgaagataga cctgttttca
     6601 tagactagtc attgacaggc ttttaaatcg gtaaataatc aagaagatga ggatcttatg
     6661 acggttacag gtattattgc ggaatttaat ccttttcata atgggcacaa atacctcttg
     6721 gagcaagcgc agggcttaac ggttgttgcc atgtctggta attttatgca acggggagag
     6781 ccagcacttg tggataagtg gacaagagct caaatggcat tagcaaatgg agctgaccta
     6841 gtggttgagc tcccttttct ggtttctgtg caatctgccg attattttgc tcaaggggct
     6901 gtggctattt tggaaaaact aggcattgat cagttaatgt ttggtacaga agactattta
     6961 gattatcaaa gcttggcgac tatttatgag gcaaaagcag agcagatggc agcctatgtg
     7021 gctgacttac cagagtatct gtcttatcca caaaaaacac aacatatgtg gcaggcactt
     7081 gcagacgtat cgtttacggg tgacaaacct aatcatattt tagccttggc ttatacgaag
     7141 gcttgtgcag gtaaaggcat tgctctgact ccaattaagc gtcaaggtgc gggttatcat
     7201 tctaaaaata agttacatca gtttgcttct gccacagcta ttcgtaaaca cctttcggac
     7261 aaagcatttg tggataagtc tgttcctgac gctagcttat tattaacttc tccacaggtt
     7321 tcttgggata actatttcca attgttgact tatcaaattc ttactcatgc ggacttaaca
     7381 caaattgttc aggttaatga agagttggca aatagaatca gcgcagcaat tcggactgta
     7441 gagacaatag acgaactgat tgatcaagta gcgaccaaac gttatacaaa ggcgcgtgta
     7501 cggcgcgtgc tgacttatat tttggtcaat gccatggaaa cttcactacc tgaagcagta
     7561 catgttttgg gattctctga taaggggcgt gtccatctga agtcactcaa acaacgtgtc
     7621 tctatcgttt ctcggattgg atcagagcct tgggatgctt taacccaaca agcggatgcg
     7681 atttaccagc taggcaatcc agctatggca gaacaaactt ggggacgctg gccaataatg
     7741 cgaacagaaa aataaaatca tccttgaccc tcacgttagg tcatagctta tactgtttgt
     7801 taaggtgaga ctgagaatac tagtaactca gtatcacctt gctgaggagg aagtggtttg
     7861 aagacggtaa aagaagttag tcagttagtt ggactgagtg tgcgtacctt gcattattat
     7921 gacgagattg atttgttaaa accaacttta gttggggata atggctatcg cttttatgat
     7981 gattatgcgc tagcacagct tcaagatatt ctactgtttc gcgaattgga ctttcctttg
     8041 aagaccataa aaacattact gaatagtccg gcttatgttc aaggggcagc tcttgctgat
     8101 cagattagat tactggaaat gcgtcaacag catttgcaag agcttatcca gcatgctagg
     8161 gctttacaag aaggaggaga acaaatggga tttaaggctt acgaccattc tcatattcaa
     8221 gcctttgaag aagaggtgaa ggaacgttgg ggaaaaacag atgcttatgt ggcttatgcg
     8281 actaaaactg ctatgaagcc agagcaatta tggcaagaca tgcgagaaat ctttaggggc
     8341 tttggagata tcaaggatca agctgtatct agtcaggcag ctcaaaaaca ggtagccaaa
     8401 ttacaagact atattagcca gaatctttat ccttgtgaaa tggagatatt agaaagtcta
     8461 gggcttatgt acgttagtga tcagcgtttc aaagagacaa tagatcagat ggtaggtatt
     8521 gggacagcta cttttgttag tcgtgccatt agtcactatt gtcaatccta aaaactggtt
     8581 ctttatttgt taggcaaaat cttgctatga atcatcatta ccaaaggaga catcttaata
     8641 ctcctttggt tttttgttta gccataatgg gactaatcat tgaaaagagg gtttctatga
     8701 actcctacga acttgaggaa gctccctaat gtaagcaggc agtattgtcg tcaaaattaa
     8761 ggaggaaaga tgataccgtt tgttcttatg tttaatagta acaggaatta aggtgagaaa
     8821 aaagaaagaa aaacctgcta ttcctgagat ttacctaata aactagtgac aagtctttgt
     8881 tttagcgata tacttaacta gtaaaaaatt aactagttaa tagtttaaat atgatttttt
     8941 aaaggagtat aatcattaac aatgaaacca agaaaacgtt tattatgttt aatgggcttg
     9001 tcttgacctg ccagctaagt ttaccgcttg tcagtcacag gtcaaaacag ataaggcagc
     9061 agaacctaaa aagcatcaca ctcataaaaa gagtaagaaa acaagtgctg ttaggagtaa
     9121 gaaaaatgat aagaaaaccg gcgttgctgg gattgataag ccaacagatg atggtttttt
     9181 attgacagat gaatcataaa ttgaaagtaa aacggcaaca ggaattatcg tgaaacatga
     9241 tggtcatagc cattttttct tctattctga tttaaaagga agtaagtggg attatttaat
     9301 tcctaaaggc tataaagatg cttcgcgcca agaaacgacc tcagcggcaa catcaaaagc
     9361 aagcacaaca ggtcatcacg gggatgcaca tgcttcagat ggttatgtct ttaatcctaa
     9421 tgatattgtg tcagaagatg ttaacggcta tacggttcgt catggagatc actatcacta
     9481 tatctggaaa aaggatttgg tagtgactgc tcgtccaaca gtccagcaag gacctcagca
     9541 atcaccatca acaaatagct cttctgctca tcataaggat aacaagcaat caaatggttc
     9601 tgagaatggt aaccaccatg acaatattgg ttctcagcat aaccatgtgg atccattagg
     9661 ggcctatagg gttaatgcag aaggaaagaa agaattttct ggaattcact atgcaacaag
     9721 tgatgatttc ttatttgatg gtaagcacat tatcggaaac acagcggatg gtctgctagt
     9781 ggctcataat ggtcgtaaag aagatgttca tcttgttcct tctgcacaat tagtggacag
     9841 caaatgggca catttgattc cagaagacaa gcgtcagcag gctgaaaaac attatcatgg
     9901 agaagctgat gaaactccta aaacatctga aaaaggacag gtgatgacag gtgaagattt
     9961 tgtcaatcag gccaaagacc ttgatccaaa gttccaacgg attattttag acaaaataga
    10021 acgtgttttc cgtaccaatg ctgggtgctc aaaagaagaa ttgttgccat taatcaagat
    10081 tgatttggaa aataatcttt tcacctaccc gcacgatgat catagtcaca tggaacccat
    10141 tgatgcttct aagccattcg gtaacgggga taagatttat gattttgttg attacaatct
    10201 tccaggtaag ccagaattgg aaaaacacga tgtgattgga ccaattttca caaataccaa
    10261 tagttctcgt gatttagaca agaaaaaact cttagaaact catccagaat taaaagagca
    10321 aattctagat attaatagtt tttacgcctt gagtttctta gcgcaagata gtggtggtca
    10381 agaaggttac atcaaacagc caggctctct tcgtgttgga agtcaagaga ctcaagctgt
    10441 tacctatctc atcaaaaaag ggcaaacgat taacaacttg aaaatagagg taccaactcc
    10501 tctagctaag gagcagtatt tctttaaaaa atggtccagt cagttgccaa cagatggtaa
    10561 actggagaaa gattgggttc ttacagcagc cttccgtcat gataaacata aaaataccca
    10621 ggctttcttt accggagacc ctaaagattt agatgtgaat attggggatt attccgtcgt
    10681 gaatttcaca acgctaaatc atgggaaatt aaactataaa ggtaactcac ttgcaggctt
    10741 tagtttccga gtccgtaata atttaacatg gaagagtgtt ctagatagtg gtttcatttt
    10801 cccgacacct gttccaaatg atgataatat cgaatttatt cgttggggag gatcagtaga
    10861 ttttccggaa ggagcagctg tcaataataa agtcgaggca agtattttct tggctaaatt
    10921 tggtctaaaa cgtccaatta ttggggcata tgttccaagt gatgctaaga atccgactaa
    10981 gactgatgat ccaaaacgtt tgcacccgaa tagtgtgaca gatccttatg atgaatcaaa
    11041 atatatgacc attgtgatcg atgcaggtga acacgcaaca ttgcggacac attctacgga
    11101 gagtcgtcaa ttagcgtttg tagtgcgtca aggaacaaca tgggatgaat ttgcgaaaac
    11161 tttggtaaaa gtagcagtga ttcctgaaaa aggctatgtt tataaaggac acgatttagc
    11221 cctttcaaaa ggatctgaca aggttcagcc tggtgtttat aaggaaatag tggttgaaca
    11281 ggcgtctgat aaggacaaaa aaccatctca ggacaactgg ttggatgaat tcacaaaagc
    11341 tgaagagaaa gatactccag aaaaaacaga tggagctaaa ccagggaagg aagcagaggc
    11401 tgaaaaacca gtaggaccta aatcagaaac taatagtcca gaaaaagctg ataaagaacc
    11461 tcaaaatgca actcctatta gtccatcaac tgatcaggaa aaacctaaca aatggcactt
    11521 aggggatgat gagccagtat ctggggaacc tgcgccatta cctcctgtat ctgaagaaga
    11581 cggagatgac ttattgcctt aactcctaag aaatggttat gttaacacat ctttaaaaag
    11641 aaacctatgc cagaacatta atcgttctga gcgaggtttc ttttgtgttt ttccttgaaa
    11701 gttctttttt ttaaaaagta aacctatata ataaacctag gtaacaataa aaaggagact
    11761 aaaagtgaat aaaacagaag ctttagctat tttgacaagt ggagcagatt ggtggcaata
    11821 ctacgcccaa gctatcctag taaagcagga gaagtcaggt aatcgtattc ggctaaacac
    11881 gcttttaaat gccaaaagtg gtctttgttc agaagattgt gggtactgtg cccaatcaaa
    11941 agacagcaag gcgcctatta atcgctatgg gcttttacca aaagatgaga ttattcgtaa
    12001 ggctctaatt gctaagaaaa ataaatcaag cgttttttgc attgctttga gtggtacacg
    12061 acctacaacg agagaaattg cccttttatg tgatgcgatt caagaaatca aacacgctat
    12121 ggatatggaa atttgtctct ctattggtct ggtgactaaa gaacagattc aactcttaaa
    12181 agaggctggg gttgaccgat tgaaccataa cattaatacc cctcgtgaga attatgataa
    12241 gattaccacg acacatacct atcaagaccg cgtggatact cttgaaatgc ttaatgaaat
    12301 aggggtagac acttgttcag gttttatttg tggtatgggt gaaacggacc agcaattggt
    12361 agatatggcc tttgagctaa agactttagg accttattct gttccagtta attttttact
    12421 gcctatcgat gggacaaaat tagaggggca ccaccaacta acaccaacaa aatacctaaa
    12481 aatcctagtt atgctccgct tattatttcc tgaaacagag ttacgagtta gtgcaggtcg
    12541 ggaatatcat ctgggagaac tccaacaaat ggccttgtta attgtagatt cgatcttttt
    12601 aggaaattac ctgactgaaa agggagcaga catttcagat gatcaaaaga tgattgatca
    12661 gttaggttta gctgttgagg gagtttgtta ggtctagcaa ttgacttgtt agttacaacc
    12721 tattacggtg tcttgcctgc cttggaattc ttaatttact atcttttttg aaagtgctat
    12781 aataagagag ttaagattcc tttcgactga gtaggttgga aaagaagact attaaaattg
    12841 ttattaaaag gagacaaaaa tgggacgtaa atgggcaaat attgttgcta aaaaaactgc
    12901 taaagatgga gcaacatcaa aggtctatgc caaatttggt gttgaaattt atgtggctgc
    12961 caaacaaggc gagccagatc cagagttaaa tacagctctt aaatttgtca ttgatcgtgc
    13021 aaagcaagca caagtgccaa agcatgttat tgataaagcg attgataaag ctaaaggaaa
    13081 cacagatgaa actttcgtag agggacgcta tgaaggtttt ggtccaaatg gttcaatgat
    13141 tattgtggat actttgacat caaatgttaa ccgtacagcg gcaaatgtac gtacggctta
    13201 cggtaagaac ggtggcaata tgggagcttc aggatctgta tcctacttat ttgataaaaa
    13261 aggggtcatc gtttttgctg gtgatgatgc tgacagtgtc tttgagcaat tacttgaagc
    13321 ggatgtagac gtagatgatg ttgaagcaga agagggaaca ataacagttt ataccgcccc
    13381 aacagatctt cataaaggta tccaagcact tcgcgataat ggtgtagaag aattccaagt
    13441 tactgaactt gaaatgattc ctcaatcaga agtagtattg gaaggtgatg accttgaaac
    13501 ttttgaaaag cttattgacg cactcgaatc agatgatgat gttcaaaaag tttatcataa
    13561 tgtagcagat ttttaaattg acatagaata ataaaaagag ttgaaaacta tttcagctct
    13621 ttttaagtga tgcttttata agtaagtacc aggtaacata gtcgttgtta gaagataatg
    13681 aacaatagta aatcagtatc aacttgatag gaatcaatta ttagtgaact ctaattaaaa
    13741 atggtaaact agacacaaga acaaaaagga gagataggat gattaaaaaa caatatttag
    13801 gaagggcaac aattgcccta gcatcaaccc ttgtgctagc agcttgtggg tcatcaaaaa
    13861 aagctgagtc aggaaatcag gggagttcta aagaagtctt atttgcaacg gttggaacaa
    13921 cagctccctt ttcttatgaa aaaggtggtc aactaactgg ctacgatatc gaggtggcta
    13981 aagcagtctt taaaggatcg gatgattaca aggtgtcctt taaaaaaaca gaatggtctt
    14041 ctatatttac aggtttggac tcaggaaaat accaaatggg tggtaacaac atttccttta
    14101 ccaaagagcg ttcagctaag tacctttttt cttatccaat cggatcaaca ccttctgttt
    14161 tagttgttcc aaaagacagt gatatcaaga gctttgatga tatccaaggg catacgacac
    14221 aagttgttca agggactaca agtgttgcac agttagaaga ctttaataag aaacacagtg
    14281 acaacccggt tactctaaaa ttcaccaatg agaacattac tcaaatgtta accaatttga
    14341 gtgaaggcaa ggcagatttc aagatttttg acgctccaac ggttaacgcc attattaaaa
    14401 atcaagggtt agataatctc aaaacaattg aactcacctc aacagagcaa ccatttattt
    14461 attttatctt tagtcaagat caagagaaat tgcaaagctt tgttaacaag cgtattaaag
    14521 agttgactgc tgacggaact cttagcaagc ttgccaaaga gcaccttggc ggtgattacg
    14581 tgccatcaga taaagagttg aaacttccta cagctaacta aaccatctat taaccagtta
    14641 ttcatctaga agactggttt ttctgatcgg aaacaatatt atagtttatg aggttatgtt
    14701 ataaaaattg caaatagcct taatcaaaat gagatgttaa agtgcttttt gagaagtgaa
    14761 tattgtataa gaagtatgct ttgggtttta gtcctcaaat accaagtttt tgttgactaa
    14821 acaaataagg atggttagta tagcatatag tttaaaacta tgctatatgc tagccattat
    14881 caatttgaaa actatatcta attaagatac aataatgatc gtaaacaaaa tgaatcgagg
    14941 ataacgctat gtcttttaaa aaatggattg gaatagtcgg aatcgcttta gcatcaactg
    15001 tattggttgc ttgttctgaa aaacaagatg ataaaaacac tctaactatt ggggtgatga
    15061 caaaaacaga atctgatcaa gcgagatggg ataaagttga agaattattg aaaaaagaca
    15121 atatcacttt gaagtacaaa gaatttacag attactcgca acctaataag gcagttgcta
    15181 atggtgaagt cgatattaat gccttccaac actataattt cttaaataac tggaataagg
    15241 aaaataagga acatttggtg gccattgctg atacctatat cagcccaatt aaccttttct
    15301 ctggaaccag tcaagatggg aaggctaaat acaaatcagt agctgatctg ccaaatggtg
    15361 ctcaaattgc agtaccaaat gatgcggcca atgaaagccg tgccctctat gtgctgcaat
    15421 cagctggcct cattaaattg aatgtgtctg gtgatcaatt agcaaccatt gccaatatct
    15481 cagagaacaa aaagaaatta gatatcaagg aattagatgc tagccaaacg gcacgtgctt
    15541 tagtatctgc tgatgcagct gttgtcaata atagttacgc tgttcctgca aaaattgact
    15601 acaaaacctc tcttttcaaa gaaaaagcag atgacaattc aaaacagtgg attaacatta
    15661 ttgcaggtca aaaagattgg gaaaaatcag agaaggctga tgctattaaa aaactcatca
    15721 aggcctacca aactgatgag gttaagaaag tcgtggaaaa aacttcaaat ggtatagatg
    15781 tatccgtatg gtaaatttta gccattgtta taacaagagt gtggtcgtgt ttaaaacaca
    15841 tgctttcttg catgcttgag gaagagttta cgactaattt acctttagaa agctatttaa
    15901 gaccttttcc cttttaggat ttagaaacct tgggaagact attgcatgtt atcttaatag
    15961 tcatgattat gcaggcgatg aaaacattgc tatcgtagat tactgtcgcc atatcgtact
    16021 aatagaggag ttattaaaat cttatgaatg aagcaataat tcaattagat catattgata
    16081 ttaccttccg tcaaaaaaaa cgggttatcg aagctgttaa agatgtcacg gttcatatca
    16141 accaaggaga tatttatggc attgttgggt attcaggtgc cgggaaatca actcttgtgc
    16201 gtgtgattaa cctgctacag gcaccaacaa acgggaaaat cactgttgat ggggatgtga
    16261 cctttgacca ggggaaaatt caattgtcag ctgatgccct tcgccaaaaa cgacgtgata
    16321 ttggtatgat cttccaacat ttcaatttga tggcccaaaa aacagccaaa gaaaatgtag
    16381 catttgcgct ccgtcattcg tcgttaagta agactgagaa agaacacaaa gttatcgaac
    16441 tgctagaact tgtaggttta tcagagcgag cagataacta ccctgctcag ttatcgggtg
    16501 ggcaaaaaca aagggtggct attgcgcgtg ctctagctaa cgatccaaaa attttgattt
    16561 cagatgaggc cacatcagca ctagatccaa aaaccactaa acaaattttg gcgctcttgc
    16621 aagaattaaa ccgcaaactt ggccttacca ttgttatgat tactcatgaa atgcaaattg
    16681 ttaaggatat ttgtaatcgt gttgctgtta tgcaaaatgg tgttttgatt gaagaaggtt
    16741 ctgtccttga tatcttttca aatccaaaag aagccttgac acaggaattt atcacaacag
    16801 ctacagggat tgatgaggct ttagaaaaaa ttaaccaaca agacattgtt aaacatttgc
    16861 ctgcaaatgc ccttctagct cagttgaaat atgcaggaac ttctacggat gagcctctac
    16921 ttaatagcat ttaccgtcaa tttgaagtga cagctaatat tttgtatggc aatattgaga
    16981 ttttagatca tattccagtt ggtgacatga ttgttgtctt ggaagggcaa gctgaaaata
    17041 ttcttgcggc tgagaaagcc ttgcatgaag ctggtgttga tgttagtatt ttaaagagag
    17101 gagcctagat gtcacagtta attcaaactt atttgccaaa tgtttatgaa ctcggatggt
    17161 ctggagatgc tggttggggc ttagcgattt ggaatacttt atacatgacc attgtgcctt
    17221 ttattgttgg gggtgctatt ggtctcttat taggcttgtt attagtttta acaggaccgg
    17281 acggtgttat tgaaaacaaa acgatttgtt gggttattga taaagttacc tctgttttta
    17341 gagccattcc ttttgttatt ttgattgcta ttttagctag ctttacctat ttgcttttaa
    17401 gaacaacttt aggagcaaca gcggccttgg tacctttaac ctttgcgact tttccttttt
    17461 atgcccgtca ggtccaagtt gttttttcag aattagacaa gggtgttatt gaagcagcac
    17521 aagcttcagg tgctactttc tgggatattg tcaaagtgta tctcagtgaa ggtttaccag
    17581 atcttattcg tgtttctaca gtcaccttaa tttctttagt tggggaaact gccatggcag
    17641 gagctatcgg tgctggagga ttaggaaatg tagcgatttc ttatggttat aatcgtttta
    17701 acaatgatgt gacttgggta gcgactatta ttattctttt aattattttt gctatccaat
    17761 ttattggtga tagcttgact agaaggttta gtcataaata aacgaaacaa caccctaagt
    17821 aaaaacttag ggtgttgttg tttagatgat gtcattagct tttcttcgtt ttacttagta
    17881 taagtcctat taaaaaacca atagcagcaa agataatcca tcccattgag aattgcccta
    17941 atggaacagt tttttggaaa aaagttacaa cggcttctgg taaatgaaat aatacagtca
    18001 tttgtgatag tgttaggagt gcatcaaata tggcaggaat aaaggttaga ccaattgtag
    18061 ttcgatagac gataggatca ttattgaagc atttttgtgc caaaacaagg aaaattaaat
    18121 cgactgttaa tgggtataaa aggaataaaa caggagctga ccagttgata atgactgata
    18181 agccaccaaa ataaaagaaa gctgatagta aagtaaagat agttgcccaa gcaatatgag
    18241 ataaagcagg cactaattta tggaagtatt cagcacttga cgtgattaag cctgttgaag
    18301 tggttagaca ggccaggaaa atcacaacag ctagaaatgc ttgtccgatg ccacctaggt
    18361 aaaaacgaga agcatgactt aagatttgac cgccattaac tggattacca tgaagggtaa
    18421 agctgccatc aataaaagga aataatgatt gtgatgttgc tccaatacga ccgacaaaga
    18481 tatagacaag tgctaatagc aaaatggcaa tagccccaga aataagtgtt attttggtca
    18541 cttctttgtc cgtcttagcg ccaaattgtt tggtagcctc aatgactaaa atagcaaaaa
    18601 caagagaagc tagtgcatcc atagtgccat aaccttgaat taatcctgct ataaaaggaa
    18661 aatctttaaa ggcattatta acaccgaccc cagcgttaaa agcatcaccg taatttccag
    18721 caggatggac aaaggacgcg ataaccaaaa tagaaataac aactaacaac gttggcgtta
    18781 aaaattttcc gatattttca gctagcttac taggtttgat agcaaggaag taggacagac
    18841 caaaaaatag tatagcataa atagctttat tggttgtatt atctcctaag ataggagcga
    18901 taccgactga aaaagaagtg gctcctgttc ttggaatagc aaaaaatggg ccaatagata
    18961 aatacaaaat ggaagaatag aagattgcat accatttaga gatggggcgt gccaaacttt
    19021 caacatcgcc tgatccagat ttagcaacag caatgacacc gagtaaaggc aaggagacac
    19081 cagttaaaca aaaaccaatg atagaccata gaatctgatg acctgagtag atgcctaaaa
    19141 aagctgggta aatgaggttt gctgctccaa aaaatagcgc aaatagcatg aatccaatga
    19201 cgatatatac atttttttgt ttcatttata aatagtcttt ctattgatac taatccgaag
    19261 attctaacaa ttttaattat attatgtgtc aaaataacaa caaaggttat tatatctaag
    19321 attacttcga tagtcaatag aaattgactg aaaattctta gcacaaaaaa tggttaagat
    19381 atgtagctca ttcgatttga cgaatagata gaattatatt attataaaaa acatgtaact
    19441 ttagtaagga tgtaacgtat gaaaaaaata tatgatttat gggttagggt tagtctaatc
    19501 aaaaaaatag gtatcggtgt tgtaatagga gtcatgttgg gcattttggc tcctgatctt
    19561 acaggtttta gtattttagg aaagttattt gttggtggtt taaaggctat cgcacctttg
    19621 cttgtatttg ctttggtttc ccaagccatc tcccatcaga aaaaagggag acagactaat
    19681 atgacattaa tcattgttct gtatttattt ggtacctttg tgtcagcttt agtagcagta
    19741 ctgacagctt atctattccc tttgacgtta gtgttaaata cacctgtaaa tacagaatta
    19801 tcaccacctc aaggtgttgc tgaagttttt cagtcacttc tattaaaatt agtggataat
    19861 ccgatcaatg ctttagctac tgccaattat attggtgtgc tatcatgggc aattattttt
    19921 ggactagcat taaaggctgc aagtcaagaa acaaagcatc ttataaaaac agcggcagaa
    19981 gttacttcac aaatagttgt ttggatcatc aatctggcac ctattgggat tatgagtctg
    20041 gtgttcacta cgatttctga aaacggtgtt ggaatcttat ctgattatgc ttttttgata
    20101 ctagttttag taggaacaat ggtttttgtc gccttagtgg ttaatccact tattgcggtt
    20161 ttgattacac gacaaaatcc ttatcccctt gtcttgagat gtttacgtga gtcaggtctt
    20221 acagcatttt tcacacgaag ttctgcagcc aatattccag tcaatatgca attatgccaa
    20281 aaaattggat tgagtaaaga tacttattca gtgtcaattc cacttggagc aactattaat
    20341 atgggtgggg cagcaattac catcaatgtc ctaacgcttg ctgctgtaca cacttttggt
    20401 attcctattg attttctaac agccctctta cttagcgttg ttgctgctgt ctctgcttgt
    20461 ggtgcttctg gtgttgctgg gggatcgttg ttacttattc ctgtagcatg tagtttgttt
    20521 ggcatttcaa atgatcttgc gatgcaggtg gttggtgttg gttttattgt tggtgttatc
    20581 caggattctt gtgagacagc cttaaattcg tcaaccgatg ttctttttac agctattgct
    20641 gaaaatgctt tttggaaacg taaaaaagcc tagctaggtc taacatagta aaaaacatcc
    20701 ttggaaaacg ccaaggatgt ttttttatta tttaagatag ccaagataat caaatttttc
    20761 aaaggtgtgg tcattagcga tggctacaat gatagtattc ggttctaaag gttcgaaagg
    20821 tttgacattg gtatctaagg ttttaacttc tttttgacgc atgccaatca catttaactc
    20881 atatttacga cgaacatcta gttcggaaag agattgtcct tcccagcttt taggaatgac
    20941 aaattcaatc atcgaaatac catgttccaa atagatgatg ctttcgatat gacgtcttaa
    21001 cagatttgaa gctacacgtt ttccggaatc acgctcagga gtgatgactt tagttgctcc
    21061 gataccatat agaacttctt caaaaatttt atttttagcc ttggcaataa tggttggaac
    21121 accgagtttt ttacagtgca tgactgcaag aacagaagat tccaagttat tccctgaagc
    21181 gataacgaca gtatcacaat gttcaatccc tacagctaat agaaattctt tgtcagtaat
    21241 atctccaaca gcggctttag tgaccaagtc ggccacctct ttaacatgac tttctctgat
    21301 atcaatagca ataacgtctt gatcaaaatt acttaattct ctggcaacag tacggccaaa
    21361 aataccaagg ccaagaacgc cgacagtttt acgttttaac atgttttctc cttaacccac
    21421 taaaatatca gtagtggcat attgaatggt tttttctttt cgttgaatca gactgatgag
    21481 gacagtaatt gggccaacgc ggccgacgaa catcaagaca atgacaataa gacgtccagc
    21541 agtagacaat tgtggtgtca aatccataga taccccaact gtcgcgatgg cagaaataga
    21601 ttcaaataag agtggtatag gagcgatatg aggctccacg ctaagtaata aaataaaacc
    21661 tatcataaga actgcaaaaa agaagataag aactgtcatg gtctgcttaa ttgtcttatt
    21721 tgcgataatt cggttacgaa aggtaacttc tgattgccct gaaagttccg ctttaaagag
    21781 taagaaagta atggcagcag tcgtcacttt aatcccacca gctgttccac caggagcacc
    21841 accaataacc atttgaatca tataaagaat gttagttggt gctagggtat cgttataaga
    21901 gattgttgca aagccagctg ttctcatagt gactgtttga aaaaatgaaa ccataagttg
    21961 ctgatgtaaa ctaaaattgg caatggtttt gctgttatct ttttctaaaa accaggttaa
    22021 gaaggttcca agaaaaagaa taacagctgt ggtttgtagt actagacgag actgattgga
    22081 taatttacga aaagttgccc cataacaatg aggtctttca aaaaagtatt ttttaaaagc
    22141 tactcctaaa tcaacccaaa ccgcaaaacc aagtccacca gagataatca agaacgtaat
    22201 gataacattt aatgtaggat ttaacataaa gtcttttaaa ctagaagatc ctaaattgtc
    22261 aaaaccagcg ttacaaaatg ccgacacagc tagaaaaata ctattgaaga taccattttt
    22321 ccacccgaag cgggggataa agtcaatcat gataactagc gcagcaaagg cttctagact
    22381 aaaggttact ttataagcaa aaaaaaggta gtgctttaaa tctttgctat cacctcgatt
    22441 taacgctgat tggagcaagg tttgatcgct caatcgcatt tttcgcttga gggcaaaagt
    22501 actcacagct attaacgtca ccaagccaag accaccaatc tgcattagtg ccatagcaat
    22561 ggtttgtccg ataccgttat acacttcagc gacgggaaca acagaaagtc cagtcacaca
    22621 aaccatggaa accacattaa agaaatgatc aagatagacg gtattaggac cattttgata
    22681 atgggtaaag ggcatggata acaagagagt tccaatcaga atcacaatgg caaaactaaa
    22741 tgttaagcgc tgtgtgactg aaagagattt gataaaagag cgtttcatgt ttcctccaga
    22801 cataatatct cctactataa taacaaaaat aagttaaaaa agctaagttt catcttagcc
    22861 tttggtacta tttatagagg ttttttgtta ggcaagccag cttttcttgg atacttgtta
    22921 ggtgtttcct ttttcttttc aacaatggtg atgaagcgag aatctccatt tggcaattgg
    22981 tagctatggt ttttaatgac tttaccaaaa agaagacaaa gagcattctt agcttcttct
    23041 aactcttggt cagcagcttg tgcctttaag gcgattaatt ttcctccaat ttttaaaaag
    23101 gggatggtta attcagatag aacctgcatc cgagcaaccg ctctggcagt aacgacatca
    23161 aattgacctc gaaaggcctt gtcctgtccg aaatcttctg ctctaccatg aaaaaaatgg
    23221 acattttcca agcccaattc ctgagcaagg agtgtcagaa aagaaatccg cttattaaga
    23281 gaatcaataa tggtaacctc aaggtttggg aaaagaattt tcatgggtag gctaggaaaa
    23341 ccagctccag ctccaatgtc caataatttg attggttcat tagctaaaaa gccctgtaaa
    23401 ataggagcga tggaatcata aaaatgcttg aggtaaacct cattttcttc tgtaatagct
    23461 gttaaattaa ttttagtgtt ccattccact agtaatttga agtaggtgtc aaattgctct
    23521 ttttgcttcg atgataagga aaaaccatct ttctctagtg ttcggtaaaa gtcttggggt
    23581 gtcattagtg tcctctgttt ttgatagttg ttaccatttt atcataaaat agcccataac
    23641 aaaatccaat aaatcatcag aaataacacc tcattacttg ctattagcct agaaattgct
    23701 ataattgaga cacaaagatt aaaggagacc cactatgcca acagttttga ttatcttagt
    23761 cgttttagga gtgcttgcgc tatggttaat gattagttac aatagcctgg ttaaatctcg
    23821 gatgcacaca aaagaagctt ggagtcagat tgatgtgcaa ttaaagcgtc gtaatgactt
    23881 gattccaaat cttattgaaa ccgtaaaggg atatgctagc tacgagcaaa agacatttga
    23941 aaaaatcact gatttgcgtg cgcgtgttgc gaatgcttca actcctcaag aaaccatggc
    24001 agcttctaac gaattgagta aacaagtgac cagtttgttt gccgttgctg aaaattaccc
    24061 agacttaaaa gctaacgaaa acttcttgaa attacaagaa gagttgacca atacggaaaa
    24121 taaaatctca tattctcgtc aactctataa ttcaacaacg tctaattaca accttcaatt
    24181 agaatctttc ccaagcaata tcgctggtaa attatttggt tttaaaccaa gtgaattctt
    24241 acaaacacca gaagctgaaa aagaagttcc aaaagttgaa tttaactttt aaatatgaaa
    24301 ttatcatcta gtaggcaatc ataagagaaa ggagaattat gctttatcaa cagatttcac
    24361 aaaataagca acgaacagtt gttttattag ttgttttctt cgctctctta gcacttattg
    24421 gagcttcagc aggctatctg ctgttagata attatgccat gggcttggtt cttgctcttg
    24481 tcattggggt gatttatgct accagtatga tttttcaatc caccagtctt gtaatgagta
    24541 tgaacaatgc tagagaagtt acagaaaaag aggctccagg ctttttccat attgtcgagg
    24601 atatggctat ggtggcccag attccgatgc cgagagtttt tattattgaa gatccttctt
    24661 taaatgcttt tgcgacagga tctagccctc aaaatgctgc tgttgcagca acgacaggtt
    24721 tacttgaagt catgaatcgt gaagaacttg aaggtgttat cggccatgaa attagccaca
    24781 tccgaaatta tgatatccgt atttcgacta ttgctgtagc tttggcgagt gctgttaccg
    24841 ttatttctag tatcggtggg cgtatgctat ggtatggtgg cggttctcgc aggcaaagag
    24901 atgacggaga tgatgatgtt ttaagaatca ttacattact tttgtcgtta ttatctttgc
    24961 ttttagcgcc cctagtagca agtttgattc agttggctat ttctcgtcaa agagaatatc
    25021 tagctgatgc tagttctgtt gaactaacaa gaaatcccca aggtatgatt aaggctcttg
    25081 aaaaattgca gttatctcag ccaatgaagc atcctgttga tgatgctagt gcggccttgt
    25141 atattaatga gcctcgcaaa aaaaggagct tcagttcatt attcagcacc catcctccta
    25201 ttgaggagag gattgaaagg ttaaaaaaca tgtgagcgtt tggggttttt gctcaagcct
    25261 cactttttta tgtctttggg cagataatct aaaattgcag gaattatcaa aagtatccga
    25321 acaaaaagaa aaaaatgagt gaaacaatgg ttaaaaatag aaagatttaa atcttaaaat
    25381 taaaaaacgt cagaaaataa atgcaaaact attgacaaat cttttagata gtagtaaaaa
    25441 taaatgagag ttttattagg agaagatgat gttagctatt tccgaaatca gaaaacaccc
    25501 agacggtctc tcgtttgatc gtttatgtga tgtcaaaagt atgttacttg agcgtgacca
    25561 acagattatt gacataaagg cagttaaagc tgtcggtaat gttcgctatg ataaggggct
    25621 ttatctgtta gattatcaat tgagttacga agtgatatta ccgtctagcc gttctatggt
    25681 tccggtctgt ttaagtgaag tccaacacat tcaagaatta tttatagagg cgacagattt
    25741 agctgataag aaagagttgg ttgaagacaa tctggtatta gttttagaca aagacgctat
    25801 taacctcgaa gaaagtattg tggataatat cttacttgct attccgctac aggtcttgac
    25861 agaggaagaa aagaaatcaa aagagttgcc agcaggtcaa aattgggcag ttttgacaga
    25921 agaagactac cagtgtctaa aagaagaaaa gcaaaaagaa aataatcctt ttgctagctt
    25981 gcaagggttg tttgatgaat aaaactgaat attaaagatg tctgtaattt ttatttgaaa
    26041 aaacagctat tctttgatat actctttaga gaatatggtt acttatctaa agtagaaggt
    26101 attttgacca tagagggcaa agaaggtaat gactattaga tgcttcatat tttattcgct
    26161 agaagactat ttgaccatta gaactgaaat agtctaggat atgagatgga tttcatagtt
    26221 ttctttctgg gagaaaaaga tagattaaga ggataagggt tggtataaat gacaaagaaa
    26281 attttaatta ttgaagatga aaagaatctg gctagattcg tttctcttga gctgcaacat
    26341 gagggttatg aagtcattgt tgaggtcaat ggtcgtgaag ggttagaaac tgctttggaa
    26401 aaagagtttg atttaatcct gcttgactta atgttaccag agatggatgg ttttgaagtg
    26461 acccgtcgtt tgcaaaccga aaaaacaacg tatatcatga tgatgactgc gcgtgattct
    26521 attatggatg tggttgcagg tttagaccgc ggtgcagacg actatattgt taaaccgttt
    26581 gccattgaag aactacttgc ccgtattcgt gctattttcc gccgtcaaga tattgaatct
    26641 gagaagaaag tgcctagtca aggcatttat cgagatctag ttttaaatcc acaaaaccgt
    26701 tcagttaatc gtggcgacga tgagatttct ctcactaaac gtgaatatga tttgcttaat
    26761 attttgatga ctaatatgaa tcgtgtcatg acacgtgaag aattattgtc aaatgtttgg
    26821 aaatatgatg aagccgttga gactaatgtt gtagatgtct atattcgtta tctccgcggc
    26881 aaaattgaca ttccaggcaa ggaatcttat atccaaacag tgcgtggcat gggatacgtt
    26941 attcgtgaga aataagtcat atggaaaatc agaaacaaaa acagaagaaa tataaaaact
    27001 cgttaccaaa acgactatct aatatctttt ttgttctttt tttctgcatt ttctctgcct
    27061 ttacactgat tgcctatagt tcaacaaact atttcttatt gaagaaagaa aagcagtcag
    27121 tctttcaagc tgtaaatatt gttagagttc gtctttctga ggtggactct aattttacat
    27181 tagagaactt agcagaagtt ttgtacaaaa acgataaaac acatctgaga attgatgaca
    27241 gaaagggcag tcgagtcatt aggagtgagc gcgatatcac aaatactcta gatgcgaatc
    27301 aagatattta tgtctataac attgataaac agatgatttt taccacagat aacgaagaat
    27361 catctcctgg cttgcatggt cctatcggtc gggtgtatca cgaccatatc gaagatcagt
    27421 atcgtgggtt ttccatgaca caaaaggtat attctaatcg gactggaaaa tttgtgggct
    27481 atgttcaagt ctttcatgat ttaggcaatt attatgtcat tagagcaaga ctgctgtttt
    27541 ggctactagt tgttgagtta tttggcacaa gcttagccta tttaatcatc ttaattacta
    27601 cgcggcgctt tttgaagcct ttacacaatt tacatgaagt gatgcgtaat atctctgaaa
    27661 atcctaataa tttaaacctg cgctcagata tttcgtcagg agatgaaatc gaagaattgt
    27721 ctgttatctt tgacaatatg ttagacaaat tggagacaca tactaagttg caatcacgtt
    27781 ttattagtga tgtcagccat gaattacgaa caccggttgc gattattaaa gggcatattg
    27841 gtctcttaca acgttggggt aaagatgaca gtgatattct tgaagaaagc ttgacagcaa
    27901 cagcgcatga ggctgaccgt atggcaatca tgattaatga tatgttagac atgattcgcg
    27961 tacaaggctc atttgaggga catcaaaatg atatgacagt tttggaagat tctattgaaa
    28021 ctgttgttgg taattttaga gttttaagag aagattttat ctttacatgg cagtcagaaa
    28081 atccaaaaac gatagcccgt atttataaaa atcattttga gcaggctttg atgattctga
    28141 ttgacaatgc tgtgaagtat tcccgtaaag aaaagaaaat cgcgattaac ctttcagtga
    28201 ctggcaaaca agaagctatt gttagagttc aagataaagg cgaaggaatt tctaaagaag
    28261 atattgaaca tatctttgaa cgcttttata gaacggataa atcacgtaat cgaacaagta
    28321 cccaggctgg attagggatt ggcttgtcta ttctcaagca aattgtagat gggtatcatt
    28381 tacagatgaa ggttgaaagt gaattaaatg aaggttcagt gtttatctta catattcctt
    28441 tggcccagtc taaagagagt tagagtagct taaggcattg ttaatgtgac aggtatagta
    28501 tgtaatcatt agataatagt agcagtcttt tgccacaact ggttagaagc tgatgctatt
    28561 tttttagcaa tgatggatga catgaaagaa atactgtcaa tcgcgatgcc ttttgttatc
    28621 cttgagaata tggtaaaata gtgtattaga ttaatttgat agaattgggg tgtttgcgtg
    28681 cgttgtccaa aatgtaatta ccataaatcg agtgttgttg acagtagaca agctgaagac
    28741 ggcaacacca ttcgtcgtcg aagagaatgt gaacagtgtc atactcgctt tactaccttt
    28801 gagcgtgttg aagaactccc tttattagtc atcaaaaaag atggcacacg agagcaattt
    28861 tctagagata aaatattaaa tggggttgtc caaagtgcgc aaaaacgacc tgtctcgagc
    28921 acagatattg aaaatgtcat ttctcgtatt gaacaagaag ttcgaacaac ctacgaaaat
    28981 gaagtgtcaa gtactgctat tggtaattta gtgatggatg agttggccga actcgatgaa
    29041 atcacatatg tacgctttgc tagtgtctac aagagtttca aggacgttga tgaaatcgaa
    29101 gaacttttgc aacaaattac gaatcgcgta cgcggaaaga aaaaacgttt aaataatgat
    29161 gaaaccaatt gatactttta catatctaaa acgcaacaaa gtaactcttg attcggtgac
    29221 tttaatacag ttgtactttc caattattgg aagtgacgcg gtctctatct atcaatactt
    29281 tattcacttt tttgacgatg gtttacaacg tcataaattc agcgatattt taaatcacct
    29341 acagtttggt atgaaacgtt ttgaagatgc tcttgccata ttgacagcaa tggaattagt
    29401 gagtgtgtat cagctatcag atacatatct cattacgttg caccagccgc ttagccgtga
    29461 cttgtttttt caacatccag cttattctcg attattagaa caaaagattg gagaggtagc
    29521 tgtctctgag ttgcaggtaa ctgtcccaag tcaagcaaga aatatttcta agcgattttc
    29581 ggatattttt ggggtgcaag gaaatttgac gaacgtacct caaaagccac aaaagaattt
    29641 tgacctttca agtttccagc aattaatggt tcgtgatggg ttacaatttg aagataatca
    29701 aaaagatatc attagccttt acagtattgc tgaacagtat gatatgacgt ggtttgatac
    29761 ttatcaaata gctaaggcga cggctgttaa tgggaaaatt cgacctgaac gcttattggc
    29821 taaaaaaaat caaagcatga caaaaccaag caaagaaaat ttttcgcagg ctgagcaaat
    29881 tattttgcga gaagcaaagc aagacagtgc tttagtcttt ttggaaaaaa ttaaaaaggc
    29941 tagacgtgca acgattacta aggatgaacg cattttattg caaacattgg ccaaaatgaa
    30001 ttttcttgat gatgttatca atgtcatggt gctttatacc tttaataaga caaaatctgc
    30061 taatttacag aagagttatg tcttaaaaat ggccaatgat ttcgcctatc aaaaggtgtc
    30121 aacggctgaa gaagctatag tggttttgcg agccttcacg gatcgtcaaa gtcgtcggca
    30181 atcaaaagta aaaacaagtc aaagtaatgt gcctaagtgg agcaatcctg attaccaaga
    30241 gacaacaagt caagaagagc aggcgaaact agatcagttc aaacaggctg ctttgaagag
    30301 gttagaaaac ctaggaaaag ggggtgacta gatggaaaag attggagaaa ccatggcgaa
    30361 attgggtcaa aacactcgtg ttaatagcga ccagttgatt caaaccattt tagcggatcc
    30421 tgaagtagca agcttcatca gtcaacatca cttatctcaa gagcaaatta accttagctt
    30481 atctaagttc aatcaatttt tggtggaacg ccagaagtat caactcaaag atccctctta
    30541 tattgctaag ggctatcagc ctattctagc tatgaatgag ggctacgctg atgtgtctta
    30601 tttggaaacc aaagaattgg tagaagctca aaaacaggca gctatctctg aacggattca
    30661 actggttagt ttgccaaaat cctatcgcca tattcattta tcagatattg atgttaataa
    30721 tgcgagccgt atggaagcct tctctgctat tttagatttt gtggaacaat acccatcagc
    30781 agagcaaaaa ggcttatatt tgtacggaga tatgggaatt ggcaagtctt acttgttggc
    30841 tgctatggcc catgaattgt ctgagaaaaa aggtgtgtca acgacccttc tacattttcc
    30901 gagctttgcc attgatgtaa aaaatgccat ttcaaacggc tctgttaaag aagaaatcga
    30961 tgcggtgaag aatgtaccag tgctcatttt agatgatatt ggtgcagagc aagccacttc
    31021 ttgggtccgt gatgaggtgt tgcaggtgat tttacaatac cgtatgttag aggaattgcc
    31081 aaccttcttt acctctaatt acagctttgc ggatttggag cgaaaatggg caaccatcaa
    31141 aggaagtgac gaaacttggc aggccaaacg tgtcatggaa cgcgtgcgtt atttggctag
    31201 agagtttcat ttagaagggg ctaaccgccg ttaagtttga gatagcaatc aagaagaata
    31261 gctacacgta tgagtgagtg aaagaaaagg agaatcatgg ttttacctac cgttgccatt
    31321 gtgggccgtc caaatgtggg caagtccacc ttatttaatc gaatcgcagg agagcgcatt
    31381 tcaattgtag aagacgttga aggggttact cgtgaccgta tttatgctac tggggagtgg
    31441 cttaaccgcc aattttcatt gattgataca ggtggtattg atgacgttga tgccccgttt
    31501 atggagcaaa tcaagcacca ggctcaaatt gccatggaag aagctgatgt tatcgttttt
    31561 gttgtttctg gcaaagaagg ggttacggat gcagatgaat atgtgtctaa aatcctatac
    31621 cgaaccaata ctccagtgat tttagctgtc aacaaagtgg ataatcctga aatgcgtaat
    31681 gacatttatg atttttattc acttggttta ggggatccct atccagtttc ttctgttcat
    31741 ggtatcggaa caggggatgt cttggatgcg atcgttgaaa acttgccagt agaagaggct
    31801 gaagaaaatg atgatattat tcgcttcagt ttaatcggtc gtcctaatgt tgggaaatct
    31861 agcttgatta acgctatttt aggtgaggac cgtgttatcg ctagccctgt cgcagggaca
    31921 acacgtgacg ctattgacac gcattttacg gatgctgacg gtcaagaatt taccatgatt
    31981 gacacggctg gaatgcgcaa atctggcaag atttacgaaa atacagagaa atattctgtc
    32041 atgcgtgcca tgcgtgccat tgaccgctcc gatgtggtct tgatggttat cagtgctgaa
    32101 gaaggtatcc gtgaatacga caagcgtatc gctggctttg cacacgaagc tggtaaagga
    32161 atgattatcg tggttaacaa atgggatacc attgacaagg ataatcatac cgttgctaag
    32221 tgggaagccg atattcgtga ccaattccaa tttttgacat acgctccgat tatttttgtg
    32281 tcagctttga cgaagcagcg cctcaacaaa ttgcctgact tgattaaacg tatcagtgag
    32341 agtcagaata aacgtatccc atctgctgtc ctcaatgatg ttatcatgga tgctattgcc
    32401 attaatccaa cgccaacgga taagggtaaa cgtttgaaaa ttttctatgc cactcaagtg
    32461 tcagtaaagc caccaacatt tgtcgtcttt gttaacgagg aagaattgat gcacttctct
    32521 tatctacgct tcttggaaaa ccagattcgc gcagccttta cctttgaagg gacaccgatt
    32581 catctgattg ctcgcaaacg gaaataagaa atgaacatca actaaaatgc tgacctaaga
    32641 aataatctca tcattgataa ggactgtgtt gtgtatgtta caggagacag tcctttttat
    32701 aataccttta agggtgtaga cggaagatta gtagcaaaca aagaaaaagg attttgacaa
    32761 gaaatatcag tcggtttttg ctataatgaa aggataagca aaaaggtgga aaaatgatgg
    32821 ctagattaat tccaggacga gtaaggaatg aaggtattaa gctttatgag caaggtttag
    32881 tctcattcca agatgataat aaaggcattc ttcaaataga agtggagact tatcaggttc
    32941 aatatggagc agatgatgag gatatcactt gtcaatgcga cacatttcat atgaaacatt
    33001 attgcaagca tattgcagca gtcgagtatt ttttaaaaaa tgatcaaaaa ggtaagcttt
    33061 ttttaaaaca gttaacaaat caaacaaaaa tcaaagaaac aacaaagaaa atgacatctt
    33121 ttggtagcct ctttttagat agcttagcca tgaatgaaga tgattctgtt aaatacaggc
    33181 tgtctgctct tggtagtcga agcccttttt cgtcagatta ctggtggagt ctgaaaatca
    33241 atcgtttacc agatgatcgt tcttatgtga ttcgagatat taaaggcttt ttgcagctta
    33301 ttaaaaaaga aggcttttat cagattggaa aaaattattt tgaacaactt tcatggctgc
    33361 agtttgaccc atccagtcaa gaccttattg agtttttatg gcgcttagca tctgatactg
    33421 acaaagggga caacgagaac atttttccaa atcatgcaag gcatttgcgc ttacctagtg
    33481 gtttttttga agaaggcatt cactatttga cgtcacttta tgactttact tttgaggggc
    33541 cttctcaaac ttatcatcat ctttttgtcc gttctttgga agcagaggca ggcctttatg
    33601 agtttaaagt ggaagtgcat cgcaaatcta ttgaattgca aattgctgaa aaaaatgtgc
    33661 aatacctctt tgataatgac tatcttcttt atcaagatac cttttatcac ttgacgttaa
    33721 agcaacgaaa aatggttcag gctattcgta gtctgcccat tgagaccgac ttggctaaac
    33781 atattcattt tgatttggat gatcatgcga aattagctgc aagcttatca gattttaaac
    33841 agatcggtct agtagaggct cctaaaagct ttgctattag agactttgag gtgacttttc
    33901 aatttgattt gttaaatcga gatgaaatca gttgtcagct tatgtttgat tatggcaatt
    33961 accaagttag tgacaaagca agtttagaag cacttccttt tgctagtcat ttaaaaaaag
    34021 aagaaaaaat caatcgttct ttacttgctt ttggcttctc gccacaattt tactcaaaaa
    34081 agcgactaac aagtgcaaaa gagctctata ctttttttga agaaacagtt ccatgttttg
    34141 agcgcttagg taatgttgcg ttgagtacag ctatccaagc attacaagtg aaagaaatgc
    34201 ccaagatcgc tattagacgc aatcagggat tactagatat ttcgtttgat ttttcaacca
    34261 ttattgaaaa tgatattgac caagctgtta cagctctttt tcaaaataat ccttattttg
    34321 tgagtcaaac aggtcaatta gtggtttttg atgatgaaac tcaaaaagtt agcaaaagtt
    34381 tacaagaatt aagagcaaga cagctaaaaa atggtcactt gcaactggat ggcattagag
    34441 ctctacaagt atccaaactt tttgaaggca tgacatctgt tcatttttca aaggaattag
    34501 aagagttagc ctatcatttg cagcatcctg aaactttttc aataaaaccg ttaccagtta
    34561 aggctcaaat gcgagattac caacgcaacg gtgttcagtg gttatcaatg ctcaatcatt
    34621 atggctttgg tggcatttta gcagatgaca tgggacttgg aaaaactctc cagacacttg
    34681 cttttttagc tagtcacctg aaatcagata gtaaagtgct cattttatct ccatctagtc
    34741 ttatctataa ttggtttgat gaatgtcaaa aattcacacc tcagctagat gttgtggttt
    34801 cttacggact taaacaaatc agagatcaaa tcatcgaaga aggtcatcaa ataaccataa
    34861 ccagctattc ctcctttaga caggattttg agacctatca agcgtttcac tacgattatc
    34921 ttatcttaga tgaagctcaa gtgataaaaa atgcacaaac taagatttca cactgtttac
    34981 gtgcgtttaa tacagccaat tgttttgcgc tttcgggcac tcctattgaa aataaaatgc
    35041 ttgaaatttg gtccattttc caaattgttt tgccagggtt gctaccgact aaaaaagagt
    35101 ttttaaaatt aacagctgag caagtatcac gctatatcaa accctttgtg atgcgtcgta
    35161 aaaaagaaga tgtcctacca gaattacctg atttaattga aactaattat tcaaacgaga
    35221 tgacagatga acaaaaagct atttacttag cgcagttaag gcagatgcaa gatcaaattc
    35281 gaaattctag tgatgtggat attagccgtc aaaaaattga gattttatct ggtatcactc
    35341 gattgaggca aatctgtgac actccaagtc tctttatgga ttaccaaggc aaaagtggta
    35401 agctagatag tttgcgaatc ttattgacac aaattaaaga aaatggtcat cgggctttga
    35461 ttttttctca atttagaggg atgctggact tggccaagca agagatgact gctctaggat
    35521 tgacctctta tcaaatgacg ggatctaccc ctgccaatga acgtcaagaa atgactagag
    35581 cctttaataa cggttccaag gatgcttttt tgatttccct caaggcaggt ggagttggaa
    35641 tcaaccttac gggagcagac acagtgattt taatcgattt atggtggaat cctgctgttg
    35701 aaatgcaggc aatcagtcgc gcctaccgta ttggtcaaaa agaaaacgtt gaagtatatc
    35761 gcttaatcac tcgagggacg attgaagaaa agattttaga gcttcaagaa agtaagcgca
    35821 atttggtgac tacagttttg gatggcaatg aaagccgagc aagtatgtcc attgaagaaa
    35881 taaaagaaat tttggggcta aacactcatt aatcttcctt gattttagtg acattaaaaa
    35941 ccctttaaag aagatgacac caaaagcacc ttatataacc tcgttaaaac gcttcttttg
    36001 aaatatcttt attgatatag cgattgtcat ttgctagtaa tgattaaaaa atttagaaaa
    36061 agacacgtca tagaatcatc aaggaatgct ttgaaaaata acagtattta agttataata
    36121 gaggatgcta caagaaggga gaatcaaaaa aggatggtaa aaaatcagtt tcctttagtt
    36181 gcagatggca ttgctattag tgatccagca aagcaaatgg ctctgtatga aaatgaagat
    36241 ctcattacca acatccgtgg ctattaccag gacaaggagt atgatgatat tgctagaaat
    36301 gaggagttta ctgctaaagc aacttctcgg caggcccctt ctagtaagcg cttttgtagc
    36361 gatgatgaaa aacaccatta tgtcaaagag gcgcgtcaaa aagcaaagca agatctcaag
    36421 gaaaaaagac aggcttatct tgccaaagaa atggcctatg ttcctaaaca ggtttctaaa
    36481 aagcaacagc ctgcggattc ttctccttct caaaagcaag caacaacaga aatgagtcgt
    36541 tttacaaaaa aacttcatca agacaactat attttagctg agttgccaaa agaatataaa
    36601 gagccaaaaa atcttcctca acaaggaact acaaaaaaaa ataattacga ttttttaaaa
    36661 tccagtcaaa tttacaataa taaagaaatg agacaacaac gagaaaaaac aattgcgcaa
    36721 gagcttaatc ttagtaggtt tgaggatctt ccttaataaa tctactcagc gtatgcagat
    36781 gacaaaggag ttaagatgtc aaaaacgtat cattttatcg gaattaaagg gtcaggaatg
    36841 agtgccttgg cccttatgtt gcatcaaatg gggcataagg tgcaaggtag tgatgttgaa
    36901 aaatactatt tcactcaaag aggattggaa caagcgggca tcactatctt accttttagc
    36961 gaggacaaca ttacgccaga tatggaactt atcgttggga atgcctttcg tgaaaacaac
    37021 aaagaagtgg cctatgcttt gagacaccag attcctttca aacgttatca tgacttttta
    37081 ggtgatttta tgaaatcatt tatcagtttt gcagtagcag gtgctcatgg taaaacttct
    37141 acaacgggtt tattgtcaca tgtcttgaaa aatatcacag acacatctta tttaattggt
    37201 gatggtactg ggcgtgggtc tgctaatgcg cagtattttg tttttgaatc agacgaatac
    37261 gaacgccatt ttatgcctta tcacccagaa tactctatca ttactaatat tgattttgac
    37321 catcctgatt atttcacagg aattgctgat gtgcgaaacg ctttcaacga ttatgctaag
    37381 caggtcaaga aagctttgtt tgtttatggt gaagatgacg aactaaaaaa gatcgaagca
    37441 cctgcaccta tttactatta tggttttgaa gagggcaatg attttatcgc ttacgacatt
    37501 acgcgtacta cgaacggatc ggactttaag gtaaaacacc aaggagaggt cattggtcag
    37561 tttcacgtac ctgcttatgg aaaacataac attttaaacg ctacagcagt aattgcaaac
    37621 ttgtttgtag ccggcattga tatggctcta gtggcagacc atcttaaaac tttttcaggt
    37681 gtgaaacgtc gttttacaga gaaaattatc aatgacacta ttattattga tgactttgct
    37741 catcatccaa ccgaaattgt ggcaacaatt gatgcggcta gacaaaaata cccaagtaaa
    37801 gaaattgtag caatattcca gccacatact tttactcgca ctattgcctt attagaggat
    37861 tttgcttgtg ctttaaatga agctgacagt gtttatttag cccagattta tggttctgca
    37921 cgtgaagtag ataaaggtga agttaaggtt gaagatttgg ctgctaagat tatcaaacca
    37981 tcacaagtag taacggtgga aaatgtctct cctcttcttg atcacgataa tgctgtttat
    38041 gtttttatgg gagctggaga tattcagcta tatgaacatt cttttgagga attacttgca
    38101 aatttaacta aaaataacca ataacatgtc ctgccttagg caggttttct cattctaaag
    38161 gagtttgata tgttgattag acaggttcaa ggatccgatt tggaagttat tgctaccatt
    38221 gaaagtgaca atttttcacc acaagaagca acgacaagag cagttcttga agagcgcata
    38281 cggctgatac cagatacttt tttagtggca cttatcggtc aggaaattgt tggctacatc
    38341 gaaggtccag ttgtcactac tcctattttg gaggattctt tgttccacgg ggtgactaaa
    38401 aatcctaaaa ctggaggcta tattgctatt actagtttgt ccatagctaa acattttcag
    38461 caacaagggg ttgggacagc tttgttggcg gcactaaaag atttagtagt agcgcagcaa
    38521 agaacaggtc ttattttgac ttgtcatgat tacttgattt cctattatga aatgaatggg
    38581 tttattaacc aaggaatttc agagtctcaa catggtggaa ccctttggta ccaaatgatt
    38641 tggaaacttt agaatcacag ctgattcaac tgttggtttg ttaaaaataa gtaacaaatg
    38701 catcatttaa ttgcaattag gatactttta agttataatg gcggttgatt atatttagga
    38761 ggattggctt tgaccgattt taaggataaa gaccaacagg atcagcagcg aagctttaaa
    38821 gagcagattc ttgctgagtt ggaaaaagca aatcaaatca gaaaagaaaa agaggaagaa
    38881 ctttttcaaa aagagttgga agctaaagaa gcagctagga gaacggccca gctatatgct
    38941 gaatataaaa gacaagatgc ttttcaaaaa gagtctatag cacataacaa taagacagct
    39001 aaacactctc aagctataaa agatgcggta atgacttcag aagcgcttaa accgacttta
    39061 ctttctgaaa aagaaaactc atctttaaaa acgacaaata agagagtcgt gcaggcaaat
    39121 gagcttcaag agactgcctc taaagaatct caagcaccgt taactattga gaaaggtcat
    39181 tcagtgagac gaaaattaag caaacgccaa cagactgagc gagctgctaa aaagatttca
    39241 accgttttga ttagctctat tattataacc cttttggctg ttactctagc aggagcaggc
    39301 tatgtttata gtgctttaaa tcctgttgat aaaaatagtg atgcctttgt tcaagttgag
    39361 ataccatctg ggtcaggcaa taaattgatt ggtcaaattc ttcaaaaaaa aggtttaatc
    39421 aagaatagca ctgtttttag tttttataca aaatttaaaa actttacaaa ttttcagagc
    39481 gggtattaca atctgcaaaa aagtatgagt ctagaagaaa ttgctagtgc tttacaagaa
    39541 ggtggtacag cagaacctac caagccatct cttgggaaga tcttgattcc agaaggatac
    39601 acgattaaac aaatagctaa agctgttgag cataatagca agggaaaggc caaaaaagct
    39661 aaaacacctt ttaacgagaa ggattttttg gatttagtca cagatgaggc ttttattcaa
    39721 gatatggtaa aaagatatcc aaaattatta gcaactatcc caactaaaga aaaagctatt
    39781 taccgtttgg aaggttacct tttcccagca acctataact attacaaaga aactaccatg
    39841 agagaacttg tagaggacat gctggcagct atggatgcta ctttggtacc ctattatgat
    39901 aaaattgctg ctagtggtaa gacagtcaac gaggtattga ccttggcctc tttggttgaa
    39961 aaagaaggtt caacagacga tgacagacgt caaattgcaa gtgtctttta taaccgtctt
    40021 aatagcggaa tggcactaca atctaatata gctattttgt atgcgatggg gaaacttggt
    40081 gagaaaacaa ccttggctga ggatgctact attgacacca ccattaattc tccttataat
    40141 atttatacca atacaggtct gatgcctggt ccagttgcta gctcgggggt ttctgcaatt
    40201 gaagcaaccc taaatccagc ctcaacggat tatttatact ttgtggccaa tgtccatact
    40261 ggtgaagttt actatgcaaa aacatttgaa gaacactctg caaatgttga aaaatatgtg
    40321 aatagtcaaa ttcagtaaac acaaacatgg tgcttaagca ccatgtttgt gtttctgatt
    40381 cgttcaaaaa gaaaagagag aaaacaatta tggcagaaaa aacgtatccg atgaccctaa
    40441 cggaaaaaga acaacttgaa aaagaacttg aagaactaaa acttgtgcgt cgtccagaaa
    40501 tagtggagcg tattaaaatt gcacgttcgt atggagatct ttcagagaac tctgaatacg
    40561 atgccgcaaa agatgagcaa gcttttgttg aaggtcaaat ttcaacgctt gaaactaaga
    40621 ttcgctatgc tgaaatcatt gacagtgatg ctgttgcaaa agatgaagtc gctatcggaa
    40681 aaacagttat cgttcaagaa gttggaacaa cagataaaga tacctatcat attgtaggtg
    40741 ctgctggagc agatatcttc tcaggaaaaa tttcaaatga aagcccgatt gctcaagctt
    40801 tgattggtaa aaaaacaggt gacaaggtta gaattgaatc accagcagct acttatgatg
    40861 ttgaaatcat cagcgttgaa aagacaaatt aatccgatga agccattatt tgcctaacca
    40921 ctaagtgttt tggttgctaa tggcttttct agtatcttca aatgaggttg actgttagga
    40981 aggtcaagta ttaatcgcat tgattatgag ccaagaggac tatagatcaa agatcgtttt
    41041 cgatggttat ttaataccaa aagaaaagac cagcacctta atgtactgac cccaaaaagt
    41101 tggacactat attttaagga agtgtataat ctaaggaaac tgacactaat gattgaccgt
    41161 tttgcaagac tttattaatg atttcttgct ttattttaaa tgaataagtc tgatacgttt
    41221 ccttccttaa cactatcgac tccataatga cccatcagtc aaacggtata tctcaaacga
    41281 ctacggttta ctccaaattc attggctagt tgaggccaag aaacacctga tttttttaat
    41341 gctaaatttc tagcttatct tcatagctta atttcataca aaaacacccc aatcgttaga
    41401 tttttttgat atgtcccctt tcactagatg agtccagtaa aagggggcat atcgtttttt
    41461 gtctaacttt tggagtgcag ttcataattg tgctaggttt tttgtctttc ttaacgcttt
    41521 cgctgttttc cagcattacg attggatttt atttttttag gcaagttagc ctgttccatg
    41581 ttttgtgaag gcgtaacatc cttacgagaa gaagttgatt ggtatgcttt aggcgggttt
    41641 ttagcgtatt cttctttaat ttgcttatgc aatcgaggtt ttaagaggta ggttgtgatt
    41701 aattgttgaa taatactaaa gaaaccacca actagccagt aaagaccaac accagcaggg
    41761 agtgagaagg acatgaagat catcatgata ggcatggtgt acatcatcgt cttcatttgc
    41821 tcacgttgtt cttctgaaac ggccatcatt gataaccatg attggaagaa gtaaagagca
    41881 gcgataattg ctgttaacac taaactacgg ctaccaagat caatgcccat aaaggtgctt
    41941 gttgatactc ctttagtgta ttgagcggca aaatacatgg cagaaaagaa tggcatctgg
    42001 atgagaagag gtagacatcc aatacctcca agagggttaa tcccatgagc acgctgagca
    42061 gccattaatt ctgtttgggc agccattttt tcttcctggc tacttgcctg tttgatacgt
    42121 ttgttgattg gttcaaaaac aggtttcaag aaggccattt tctcagattg ataacttgct
    42181 ttccaagatt gatatagacc tagtggtaag ataagtgttc taacaataat ggttacgatg
    42241 atgatagcca gtccataacc tagtccagca ttgtttgcaa agtaatcgat aaagtatgac
    42301 atgggttttc caagaaattc ccaaatcata cctttgggat ttccgtgagc gtctcttccc
    42361 acacagcctg tcaaggtgaa tagaattgac agtgctagtc ctgaaaagag gatgcgattt
    42421 aatgttagtt tcaatgtgtt tatcctttaa ttttaatata cttatctatt ttacagtttt
    42481 tttcagaaat tcacaatagt tctgaaggcc gatttttact tgcctatttg aaagtcctga
    42541 aagtcttcaa aattagccat ggtgacatcc acataagtga cttttgccca tttggatggt
    42601 cctttacgaa cttcttgaat aaatgtggct attttatctg aatcttttga ttgggccaga
    42661 atttcaacgg tcccatcgtt gttattccag acacgaccat aaatatctcc tatatctaga
    42721 gctaaagcat aggtagcgta tcgaaaacca acaccttgta cacgtccaga aacaattaaa
    42781 cgtacttttt gcataagaag ggcctccttg cttttattat agcacatact tagcaggaaa
    42841 tctctttagc taattgtcta cttcctgtca cttttactaa agacaagaat acaaaaatga
    42901 gatagttagt agtactaaca gtaaaagagg tttgtctatt ttaaaaatag tatcaaaaaa
    42961 aggtctttta ggtttaaaac attgaactgc ctccaaattg accatctaag aagttgatgc
    43021 tttcaaatgc tgtcgcgtat ggtataatag gcgcatggtt attacatcaa aagcaaatca
    43081 actaattaag caaacaaaaa aattattgca aaaaaagcat cgaaaacagt cctatttgat
    43141 tgagggctgg cacctttttg aagaagccca aaaatcagga caagtttttc gccacatctt
    43201 tgttttagag gaaatggtgg agcgtctagc aggtgagcaa gaactcgtta ttgttagccc
    43261 acaagtgctc aaggagttga ctgactctcc tagtccacaa ggcattgttg ctgaggtgga
    43321 gatacctaag ttagcctttc catcagatta caaagggaaa tatttggttt tagaggacgt
    43381 ccaagaccca ggaaatcttg ggaccatcat tcgtacagca gacgctgcac ggtttgatgg
    43441 ggtctttctt tctgaaaaat cagcagatat ttacaaccaa aaaaccctac gttccatgca
    43501 aggtagccat tttcatttac caatttggcg aacagatgtc tatcagcttt gtcgagagct
    43561 ccaagagtat aaaactccca tcctagcaac aactctgtca aagaaatctg ttgactataa
    43621 aagcctcaca catcatgaaa ggttggcttt ggtgttggga aatgaaggcc aaggcattag
    43681 tgctgaaatg gcagccctag cagaccaact ggttcatatt acaatgcctg gtcaggcgga
    43741 aagtttgaat gttgccgtag cagcaggaat cctcattttc agcttgattt aagctaatat
    43801 gatataataa ccaagtgagg taattatgtt atgcattata cagaagataa agaatatatg
    43861 gaacacgtcg gtcatttgat cgctcatcct cgctttcaaa aattgagtca tattgttcag
    43921 caccaacatt caacgcgtct tgaacattct atcaatgttt cttattcaag ttataaatta
    43981 gccaagcgat tcggttggga tgctaaaagt acagccagag ggggcttact tcatgatttc
    44041 ttttattatg attggcgcgt gaccaagttt aataagggtc atgcctgggt tcatcctcgt
    44101 attgctgtac gaaatgcgaa aaagttaaca gaactcaata aaaaagaaga ggatatcatt
    44161 ctaaaacaca tgtggggagc gaccattgct tttccgcgtt acaaggaaag ttatattgtg
    44221 acaatggtag ataaatactg ggctgtcaag gaagcagtga cgcctttaag acaaaaatgg
    44281 tctaatcgac ggtttcttcg ccgcaagacc ctccaaagtc ataatcgtta agtaaaggag
    44341 ttattatgaa cgatcacgtt atttatacac aatcagatgt gggattaaat cagttttttg
    44401 ctaaaattta tagtctagtg ggaatgggag tgggtttgtc tgcttttgtt tcttatttga
    44461 tgctttatcc atttagagaa aatttaatct ctatccttgt taatcagccg atgatttact
    44521 atggtgctgc gattattgaa cttattttag tttttgtagc cagtggtgca gcacgaaaaa
    44581 acacaccagc tgcattgccc atttttctta tctattctgc gctaaatggc tttaccctaa
    44641 gctttattat tgtggcatac gctcaaacga cagtttttca agcatttctt tcttcagcag
    44701 ctgtgttttt tgccatgtca atcattggtg tcaagactaa acgggatatg tcaggtctta
    44761 gaaaggctat gtttgctgct ttgattggtg ttgttgtggc tagtctgatt aatcttttta
    44821 ttggtagtgg gatgatgagt tatgtcatta gtgtgatttc cgtgctaatt ttctcaggtc
    44881 tcatcgcatc agataatcaa atgattaagc gcgtttatca agcaacaaat ggccaggttg
    44941 gtgatggctg ggctgttgct atggccttaa gcttgtattt agattttatt aacttattta
    45001 tcagccttct tcgtattttt ggaagaaatg attaacatta aaaagtgagt ataactactc
    45061 actttttaat gttaacagga taagtaaact gtaaggaaga aattcgagat agatataaga
    45121 tgaggctgct aaaagaccta gtgttaattt gtaaactctt tctttttttg gtatactatt
    45181 aaggattaaa tacgaggaga atatagatag atatgtcaac agctatttgg attttattac
    45241 ttattgttgc ccttggggta ggtgtttttg gtgggatttt tattgcccgt aaacaaattg
    45301 aaaaagaaat tggtgaacac ccacgtttaa caccagaagc tatccgtgaa atgatgagcc
    45361 agatggggca aaaaccaagt gaagcaaaaa tccaacaaac ttatcgtaat atcatcaaac
    45421 aatcaaaagc agccgtatcc aaaggtaaaa aataaaagct aattgttata ggggaaacct
    45481 ttgtgatagt tagaagtgaa cagtctttga tctcaatgtt cagtagcact tgtcttatca
    45541 gttagatttg tcaactgttc agggtttaaa aagaaactca gttggctatt tccaactgag
    45601 tttttcatat cgtcagtaag gaagtaaaca taatggatac aagaccaatt gggtttttag
    45661 attctggtgt gggaggtctg accgtcgttt gtgaattgat tcgtcagctc cctcatgaga
    45721 agattgtata tattggtgat tcagcaagag ccccctatgg tcctagaccc aaaaaacaaa
    45781 ttaaggagta tacttgggag ctagtcaatt ttttgctgac tcaaaatgtt aaaatgattg
    45841 tttttgcatg caataccgca acagcggtgg cttgggaaga agtaaaagca gttttagata
    45901 ttcctgtttt aggggttatc ttaccggggg caagcgcagc tattaaatca acgacaaaag
    45961 gccaggttgg ggtcatcgga accccgatga cagtggcttc agacatttat cgcaaaaaaa
    46021 tccagctatt agcaccatct attcaagtaa ggagtcttgc ttgcccgaag tttgtaccga
    46081 ttgtggaatc aaatgagatg tgttcgagta tagctaaaaa aatagtttat gacagtctat
    46141 caccattagt cggtaaaata gatacccttg tactaggatg tactcactat cccttgttac
    46201 gaccaattat ccaaaatgtt atggggccat ctgttaagct gattgacagt ggagcagaat
    46261 gcgtccgaga tatctctgtc ttattaaact attttgacat taacggtaat tatcatcaaa
    46321 aagctgtcaa acaccgcttt tttacaacag caaatcctga gatttttcaa gaaattgcct
    46381 cgatttggct gaaacaaaaa ataaatgtgg agcatgtcac cttatgagtg aaaaaattta
    46441 cgaatacaaa gatgaaaata actggtttat cggaaagatg actggtcata atttaatatc
    46501 gggctgggga gtcaaataca cgacaatcaa aaaaatagat gaccttttag acggtattac
    46561 cgcaacgtta gattgggaaa atcctaaagg ttacgatgtt tcggtggtgc gttatcagtc
    46621 tcctttatct ctcatcacct ttattatcga catgataaat caagagaccc agcgtaagat
    46681 taagataact ccccatgcag gcacgatttt attaatggaa aatgcgaaac tgcttgcagt
    46741 ttatctccca gaaggtggag tttcaacggc tacatttttt gcgactagtg aacagggatt
    46801 tggggatatt attttaatcg ctacacgaaa cgagggaaaa accaaagagt tccgcaatct
    46861 gtttggccag ctaggttatc gtgtggaaaa tctcaatgat tatccagaat tgccagaagt
    46921 agcagaaact ggtactactt ttgaagaaaa tgctcgcttg aaagcagaaa cgatttcacg
    46981 cctcacagga aaaatggtat tagcagacga ttcaggacta aaagttgatg ccttgggtgg
    47041 tttacctggg gtttggtcag ctcgtttctc aggaccagat gccacagatg ccaagaataa
    47101 tgccaaactc ttacacgaat tagctatggt gtttgaccaa aagaagcgct cagctcaatt
    47161 tcatacgact ttggtagtgg ctgctcccaa taaagatagt ttggttgtgg aagccgagtg
    47221 gccaggctat attgctacgc agcctaaggg agaaaatggt tttgggtatg accctgtctt
    47281 tatcgtcgga gagactgggc gtcatgctgc agaattagag gctgaccaaa agaatcagtt
    47341 gtcgcataga ggtcaagcag ttcgaaaatt aatggaggtc tttccagcat ggcaagcaaa
    47401 acaatcatag taatgagtga ctctcatggt gaccgagata tcgttcaagc cattaaagac
    47461 aagtatcttg gtcaagttga tgctattttc cataatgggg attctgaatt aaacagctca
    47521 gatcctattt gggcaggtat ttatgtcgtt ggcggtaatt gtgactatga tacaggttac
    47581 cctgatcgtt tagtaactcg attaggcaca gttacgattg cccagacaca tggtcacttg
    47641 taccatatta atttcacttg ggataaactg gactactttg ctcaagaagt agcagcagat
    47701 atttgtctat atggacacct acaccgtcca gctgcttggc aagttgggca aaccctcttt
    47761 atgaatcccg gatcagtaac acaacctcgc ggagaaatta acgagaaatt atatgctcgt
    47821 gttgaactaa ctgatactca aattaaagtt gattacttta caagagatca taaactttac
    47881 ccatcactgt ctaaggaatt taaacgatga tcgcaaaaga atttgaaacg tttttaatga
    47941 gtcatttaga taattatctt atcccggaac aagatttggc tatttttatc gacacacata
    48001 atgcagacca tgtgatgtta ctattggtga gcaatggttt ttctagagtt cctgttatca
    48061 cacgggagaa aaaatatgtg ggaaccatta gcatctcaga tattatgatg taccaatcta
    48121 aaaggcagct gacagattgg gaaatgagtc aaacagatat tggcgagatg gttaatacca
    48181 aaattgaaac cattagcatt acttctagcc taacagaaat tatgcacaag ttaattgatt
    48241 tcccattctt accggttgta gatagagcga atcgctttgt tgggattatt acgcgaaaat
    48301 ctatattaaa ggctgtcaac agtcttttac atgattttac agatgattac acgattataa
    48361 aaaaatgaag agttatattg aaccttttat tgctagcaag gctttatctc aaaatagtca
    48421 aaaagcttat cgatacgatt tgcaacagtt ttgtcaactg gttggtgaac gtgtcaatca
    48481 agacaaacta ttactttatc aaaatagcat agctaaccta agtttatctg caaaaaaacg
    48541 caaattatca acagctaatc aattcttata ttacttgtat caaataaagt atttaaatag
    48601 ctattttcga ttaacagata ccatgaaagt gatgcggact gagaagcagc aagctgctat
    48661 tattaatact gatattttct atcaaaaaac cccttttgtg tgggggcaat taatcagctt
    48721 attaatattg gagctgggtt taactccaag tgaagtagct ggtattgaag tagctaactt
    48781 ggatttaagt tttcaaatgt tgacgctaaa gactaaaaaa ggtgtgcgtg tattaccttt
    48841 atcgcaaata ctaatccctt ttttagaaca acaactcgtt ggcaaagaag tctatctttt
    48901 tgaacatcga ggcatccctt tttcaagaca atggtttttt aatcacctaa aaacctttgt
    48961 tcgaagtatt ggttatgaag gattaactgc tcaaaaatta cgagagcaat ttattttgaa
    49021 agaaaaacta gctggtaaat cgataataga acttagcgat attcttgggc tgaaaagccc
    49081 tatgacctta gaaaaatact acaaatcata atggatataa aacttaaaga ttttgaaggt
    49141 cctcttgatt tactcttaca cttggtatca cagtacaaag ttgacatcta cgaggttcct
    49201 attgttgagg ttattgagca gtaccttaat tatattgaaa ccttacaggt aatgaaactt
    49261 gaagtggctg gtgactacat gctgatggca agtcagctca tgttaatcaa aagtagaagg
    49321 ctattaccaa aggtggtaga acacatcgaa gaagaagatt tagaacaaga tctgttagaa
    49381 aagatcgaag aatatagtcg ctttaaagca gttagtcaag cgttagcgaa gcaacatgac
    49441 caaagggcaa aatggtattc aaaacctaaa caagaattaa tttttgaaga tgctatctta
    49501 caggaagata aaacggtgat ggatctattt ctagcttttt caaacataat ggcagctaaa
    49561 agagcagttt taaaaaacaa ccatacagtc atcgagcgtg atgattataa gattgaagac
    49621 atgatggctt ctattaaaca gcgactggaa aaagaaaacg ttattagctt atcagcgatt
    49681 tttgaggaat gccaaacatt aaatgaagtt atcagtatat ttttagctag tctagaattg
    49741 attaagcttc atgtggtatt tgtagagcag ttctctaatt ttggggctat catactacga
    49801 aaggagaaga aatgacgtat ttgtcacaga tagaagcgct gctatttgtt gcaggtgaag
    49861 aaggattaag tttgcgacat ctagcgtcta tgttatcatt aacgccaaca gctcttcaac
    49921 agcaattaga aaaactctct caaaagtatg aaaaagatca acattctagt ctttgcttga
    49981 tagaaacagc taatacctac aggctagtaa ctaaagaagg ttttgcagaa ctcttgcgtg
    50041 cttatgccaa aacaccaatg aaccaaagtt tatctcgtgc gagtttagag gtcttgtcta
    50101 ttgttgcata caaacaacct attacacgaa tagaaattga tgacattcga ggggtaaact
    50161 ccagtggagc tttgagtaaa ttattggcat ttgatctcat tagagaagct ggcaaaaaag
    50221 atgtggttgg gcgtcctcat ttgtatgcga caacagatta ttttctggac tatatgggaa
    50281 ttaatcattt agacgaattg attgaagtat ctgccgttga accagcagat gaagagattg
    50341 ctctttttag gacacaagac tgagttttgc ttgtcatcaa atagcaaatg gcgtttacaa
    50401 aaggatttgt tttaaggcgt tttagttgaa aaaaagcctt aaactaggga caacaaaaag
    50461 ttgctcaaaa gaaagaagaa tataatgcga attaacaaat acattgccca tgcgggtatt
    50521 gccagtcgtc gtaaggctga agaattgatt aagcaaggct tagtaacctt aaatggtcag
    50581 gttattacgg atttagcaac cactgtaaaa tcgggagacg tggttgaaat agaaggaagt
    50641 cctatttaca acgaggaaaa ggtttactat ttgcttaata aacctcgtgg cgctatctca
    50701 agtgtgtcag atgacaaagg ccgtaaaacg gtactggatt tactacctca ggttaaagaa
    50761 cgcatatacc ctgttggacg attggattgg gacacatcag gggtccttat tttaacgaat
    50821 gatggtgatt ttacagatac tatgattcat cctagaaatg aaatagacaa ggtttatctg
    50881 gcgcgtgtca aaggtattgc aacgaaagaa aatcttcgtc ccttaactcg aggaattgtt
    50941 attgatggta aaaagaccaa accagctcgc tacaatattg ttcgtgtaga agctgataag
    51001 aatcgatcga ttgtagaatt gactatccat gaagggcgaa accatcaagt gaaaaaaatg
    51061 tttgagtctg tggggctttt ggttgataaa ttatctcgta cacgttttgg gaccgtcgac
    51121 ttaaagggac taagaccagg agaagcaaga cgcttaaata aaaaagaaat aagtcaactg
    51181 cataacttag ctaatacgaa aaaatgatga aaaaactatt aatagtatct gttaaagctt
    51241 atcaaaaata catttctcct ttatctcctc ctagttgtcg ctacaagcca acctgttcag
    51301 cttatatgtt aactgctatt gaaaaacatg gtactaaggg aatactaatg gggatagcaa
    51361 gaatattaag atgtcaccct tttgttgctg gtggtgtcga tcctgttcca gaagatttta
    51421 gcctaatgag aaataaaaac acgtctaaaa acgctgaaaa ggcatgactt tatcaaaaaa
    51481 tggcttgaca ttgatagctg aagtgttata atggaaaaca agcattcgtt ggtttaaatc
    51541 aaacctgtta tgatttaagt tagcgagtca ccatcaacca cattgtttgc tgagcatgac
    51601 tccgagcagt gtggtttttt aaattaaaaa gagtaaatga gattatgacg acaaaagaac
    51661 ttatcaacaa aaacgacaaa gtaaaaaagg ctcgcaatca tattgtcctg tttcaacccc
    51721 aaattccaca aaatactggt aatattgcta gaacatgtgc tgcaactaat gcacctttac
    51781 atattattaa acccatggga tttcctattg atgaccgcaa aatgaagcgt gccggcttag
    51841 attactggga caagttagaa ctgcattttt atgatcattt agaacagttt atcaatcaat
    51901 gtcacggaca gcttcacctg attagcaagt ttgcagttaa taattattct caagctactt
    51961 atgctgatgg cgattcccat tatttcttgt ttggacgaga agatacaggc ctgccagaag
    52021 attttatgcg agaacatgct gaaaaagcac ttcgtattcc gatgaatgat gagcatgtac
    52081 ggagtttaaa tgtctcaaat acggtttgta tggtgattta tgaagccctt agacaacagg
    52141 gctttcaagg gttagagtta aagcatactt acgaacacga taaactaaaa taatggactt
    52201 tttaaaagcg tcagtttttg gcaacatgcg ttgtcagtag ctgacgcttt taaaaattta
    52261 gtcaaagcta ttgctatcta ggtttaaatc tgctatgcta gaagtgtctt cagggcaggg
    52321 tgtgattccc gaccggcggt gactagtaac tagaagtccg cgagcgcaag ctgatgtggt
    52381 gtaactccac aaccgacagt atagtctgga tgagagaaga ccgggctttt tgtgtaggct
    52441 tattttagct acacaataac gacggaactt ctttcaattt gaaaaaattg gaggaatttt
    52501 ttaatgtcaa aaacacataa aatgattatg attggtatac tttctgcgat atcatttcta
    52561 ttgatgctag ttagctttgc cattattcca ggcgcagctt ttttaaaaat tgaatttagt
    52621 attattcctg tcctatttgg tttaatgatt atggacttaa agagtgctta cttgattttg
    52681 ttattgaggt ccttattgaa actctttttg aacaatcgtg gggttaatga ttttattggt
    52741 ctcccaatga atattatcgc tatcgcttta tttgtgacgg ctttttcctt agtttggaac
    52801 cgtcaaaaaa cgcttagtca atatgtattt gctagcttac taggcacagg gttattaaca
    52861 tttggcatgg ttgttctcaa ttatactttt gccattcctt tatatgctat atttgcaaat
    52921 attgatatca gagcttatat tggtgtcact aagtatatga tgactatggt tattccgttt
    52981 aatcttgttg aagggttgat atttgcaatt accttttatt ttgtgtatat tgcaagtaaa
    53041 ccaattttag aaagatactt acactaatat gatgacaaat aaacaaacta actttttaat
    53101 agcttctttt gcattactaa cctttgttat aataggctat acggtcaaat tttttcctga
    53161 acgtttggca cttctagata atactattca agcagagatt agaggcaacc ttcctatagt
    53221 gctgacgcaa ttctttaggg gtgttactgt atttggaaat gtcatgacac aaattttgtt
    53281 agttattgtg tcggtcctag ttttattctt tatgaagtgg aaaattgaag ccttgtttat
    53341 cttatcaaat ggtgccattg cagcattttt gattacgact ctcaagctct tttaccaaag
    53401 accaagacct gctattgagc atttggttta tgctggtggc tattcgtttc ccagtggcca
    53461 tgcgatgggt agcatgctga tttttggtag cctattgatt atttgttatc aaaggctaca
    53521 ttcaaaacta ttacaatttg tgactagcat gatttttata atactaattt tagtaattgg
    53581 gttatctcgt atttatctag gggtacacta cccaagtgat attttagcag gctttgtatt
    53641 aggatttggg attttgcagt ttatttatcc tttttataag caaaaacgat ttgaatggcg
    53701 atttcttttg aaacaagact aatttttctt gagaagacat agggcttatt taaatcattt
    53761 agaataacat tggcaagcat caccccttga ttgccagtgt tattttagtt ttagttagat
    53821 gatgtgagct gatgattagt aaatacgttt agataaaaaa cgattaaagt gctatgtaac
    53881 gtcagaaaag acgtgatttt tgttgatctg tagtcattaa gtaagctgat gtagaagtag
    53941 tgaattctaa tgactgagct atcttttgca tagatgacta tcttgctagt aatgatttgt
    54001 gctacaatag aaacatgaaa aaaagatatc agacattaaa cgagcattac cgtcaactat
    54061 ttggcgcaaa aatgtttaaa gttccgattg atgccggctt tgattgtccc aatcgtgatg
    54121 gaacggtagc tcatggagga tgtacttttt gcacagtatc aggttctgga gatgctattg
    54181 tagcaccaga tgctccaatt aaagagcaat tttataaaga aattgatttt atgcaccgta
    54241 aatggcctga tgtcaatcgc tatttggttt attttcaaaa ctttaccaat actcatgata
    54301 cagttgatgt gattcgcgac cgttacgaac aagctattaa cgaacctgga gttgttggca
    54361 ttaatattgg cacacggcct gactgtctac cagatgatac cattgcttac ttagcagaat
    54421 tatcagaacg catgcatgtg acagtggagc taggcttaca gacaacttat gaagaaactt
    54481 ctaggctaat taacagagca cattcttatg atttgtataa agaaacggtg aggcgactaa
    54541 ggcattaccc caacattaat attgtctcgc acttgattaa tggattgcca aaagaaactc
    54601 atgacatgat gcttgaaaat gtgagacgct gtgtaacaga caatgacatt caaggaatta
    54661 aattgcattt gctgcatttg atgaccaata ctagaatgca aagagattat catgaaggac
    54721 gcttaaagtt gttgagtcaa aaggactatg tttcgattat ttgtgaccag ctagagatta
    54781 tccctaagca tattgtgatt caccgtatta caggagatgc cccacgagat atgttgattg
    54841 ggcccatgtg gagtctaaat aagtgggaag tattgaatgc cattgataaa gaaatggaaa
    54901 gacgaggaag ctttcaaggc tgtaaagttg actaatttgt ctcattttga cggatttgga
    54961 taggagaaaa gtgatgctaa aacgccccat tcatctctcg catgattttt tagcggaggt
    55021 tgtggataag tctagtgtgg ttgttgatgc cacgatgggt aatggaaatg atactgcctt
    55081 tttggcacaa ttagctaaaa aggtttatgc ttttgatgtg caagaacaag ctattagaaa
    55141 aacaagtgag cggttagcgc agctaggatt atcgaacgct gagctgattt tagcgggtca
    55201 tgaagcagtt gatcagtatg tgacagagcc ggtgcgtgca gcgattttta accttggtta
    55261 tttgcccagc gcagataaat ctattattac cttaccaaat accacactcc aagctttatc
    55321 aaaactacta acgttattaa tggtaggtgg acgtattgct attatggtct attatgggca
    55381 tgatggaggc agtttggaaa aagatgcttt attagatttt gtcaagcaat tagaccaaag
    55441 aaaggtttct gcaatgcttt atcagcctct taatcaggtg aataccccac cttttttaat
    55501 catgttggag aaattagcag acgtttagcc cttatccctg tgtcaagtct actagaagtt
    55561 ctgcgattat ttcggtggaa aaagaagaaa tcccataggc tttggctata aatgtgatat
    55621 aatgaagtca ctatattatt tttttaggag ttacattaac atggaagacc ctgtgagtca
    55681 gcccttagtg attcaatttt tattgttagt tgttttaacc ttgttaaatg cttttttttc
    55741 agccagtgaa atggccttag tttctctcaa tcgttctcgg gtggaacaaa aagcagcaga
    55801 cggtgataaa aaatacgctc gtttgttgcg ggttttagag gaacctaatc attttttatc
    55861 aacgattcaa gttgggatta cctttattag tttactatca ggagcaagtt tatcagcttc
    55921 tttgggtaag gtgatctcag gttggctagg taattcagcg accgcaagga cagctggtac
    55981 tatcatctcc ttggttttct tgacttatgt ctctattgtt ttaggggaat tgtatccaaa
    56041 acggattgcc atgaacctca aagacaagtt ggcgattgtt tcagccccta ttatcattgg
    56101 gttagggaga ctggttagtc cctttgtatg gctcttatca gcttctacta atttactgag
    56161 ccgacttacc ccaatgacct ttgatgatgc agatgagcaa atgacacgtg atgaaatcga
    56221 gtatatgtta tcaaaaagtg aggcgaccct tgatgctgaa gaaattgaga tgttgcaagg
    56281 agttttctca cttgatgaaa tgatggcgcg tgaagtcatg gtcccaagga ccgatgcttt
    56341 catgattgac attaacgatg atccgcttga aaatattcag gaaatcttaa aacaaagttt
    56401 ttcacgcatt cctgtttatg atgtggataa agataaaatt atcggtctca tccacactaa
    56461 gcgtctcttg gagtcaggtt tccgccaggg atttgatcag attaacatgc gaaaaatgtt
    56521 acaagaacct ctttttgttc ccgaaaccat ttttgtagat gatctcttac gccagctgcg
    56581 caatacccaa aatcagatgg ctattttgct agatgaatat ggtggtgtgg caggacttgt
    56641 gactttggaa gacttgcttg aagaaatcgt cggtgaaatc gatgatgaaa ccgataaagc
    56701 agaacaattt gttcatgaga ttggagacaa tacctatatt gttgttggta ctatgacttt
    56761 aaatgagttt aatgactatt ttgataccga actagaatca gatgatgtag ataccattgc
    56821 tggtttttat ttgacaggta tcggaaccat tccaagccag gagcaaaaag aagcctacga
    56881 aatagataac aaagacaaac atttagttct aatcaacgat aaagtcaaag atggccgtat
    56941 tacgaaatta aaattaatcc tgtctaatat agaacagatt attgaggaag actaggctcc
    57001 atgcctagtc tttttgatga aaagtgttat aatgaaaatg taaaaacgtt tacaagtaat
    57061 gaaggagatg caatgactga gaaagattat ggacaagtaa cagggatggt gcattcgaca
    57121 gaaagttttg gttctgtaga tggtccaggc attcgtttta tcattttctt gcaaggctgt
    57181 aaattacgtt gccaatattg ccataatccg gatacttggg agatggaaac caacaattca
    57241 aaaatcagaa cagtcaatga tgtcttgaaa gaagcccttc agtacaaaca tttctgggga
    57301 aaaaaaggag gaattaccgt atctggtggt gaagctatgc ttcaaattga ttttatcact
    57361 gccttattca tcgaagctaa aaaattaggt atccatacca cactagacac ctgtggcttt
    57421 acctatagac cgacacctga ataccatcag gttcttgata acttattggc agtgaccgat
    57481 ttgattttat tggacttgaa agaaattgat gaaaaacaac ataaaattgt cacgcgtcag
    57541 cctaataaaa acatattgca atttgcgagg tatttatccg acaagcagat tcctgtctgg
    57601 attcgacatg tcttggttcc aggcttgact gatattgatg atcatttgac acgattgggt
    57661 gagtttgtca aaaccttgaa aaatgtcgat aaatttgaag ttttgcctta ccataccatg
    57721 ggagaattca agtggcgtga gctaggtatt ccttatcagt tagaaggtgt taaaccacca
    57781 actaaggaac gcgttcaaaa tgctaaaaat ctgatgcaga ccgaatctta cacagaatat
    57841 atgaatcgga ttcatcagtc ataagagctg ttatagggtt gaggtttcct caacttttta
    57901 aagtattata agcagatctt ttgtaatctt cctttgattt tagggggtaa ttttgctaaa
    57961 ataaaatgaa taaacaaaat gaggtagaat gattatgtca aaaattttag tttttggtca
    58021 tcaaaatcct gatacggatg ctattgcatc atcttatgct tttgattact tatcccaaaa
    58081 agcgtttggt ttggatactg aagtcgtagc tttaggaaca cctaacgaag aaacagcttt
    58141 tgcccttgat tattttggtg ttgaggcacc acgtgtggta gagtctgcta aagcacaagg
    58201 gtctgaacaa gtgattttga cagaccacaa tgaattccaa caatccattg cagatatccg
    58261 tgaggttgag gtatatggtg tggttgatca ccaccgtgtg gctaattttg aaactgcaaa
    58321 tcctttatac atgcgtgtgg aaccagtagg atcagcctca tctattgttt accgtatgtt
    58381 taaagaaaat ggcattgagg tgccaaaagc gattgcaggg atgctcttgt ctggtttgat
    58441 ttcagatacc ttgttgttga aatctccaac aactcatgtg tctgatcacc ttgttgctga
    58501 agaattggca gagctagcag aagtgaactt ggaagactat ggaatggctc ttttaaaagc
    58561 aggtacaaac cttgcaagca aatcagaagt agaattgatt ggtattgatg ccaaaacatt
    58621 tgaattaaat ggcaatgctg tgcgcgtggc acaagtgaac actgttgaca ttgcagaagt
    58681 cttagaacgt caagaagcta ttgaagcagc cattaaagat gccatggctg cagaaggtta
    58741 ttcagatttt gttttgatga tcacggatat tgttaactca aactctgaaa ttctagctat
    58801 tggagcaaac atggacaagg ttgaagcagc ctttaacttc acccttgaca acaatcatgc
    58861 cttcttagca ggtgccgttt ctcgtaaaaa acaagtggtt ccacaattga cagaaagttt
    58921 tggagcttaa tgaaaagacg ctttaaaagg acttgatttt tttgaccaag tccttttgtc
    58981 actcttctat gttataatag aaggtatgat aacagtattt cattcagata aactcaccag
    59041 acaacctttc tttcaagacc ttatcaatta tctcgaccag catgatcacg ttatattacg
    59101 agagatcaaa aaagcctttc ctaatgtgac aggtattgac aaggccatcg aaagctatgt
    59161 taaagctggc tatattcgcc gtgaaaataa gcgttatggc atcaatcttc ctttggtgag
    59221 ttctgatcag cagctggcct tagacactat gctttttgtg gacacctgtt cagctatgta
    59281 tgaaaatatt ttagcggttg tttttgagac tcagctaaca aaccaaacca atcacgtgat
    59341 gatcaaggaa aagaccaaca tcacgagaga cgatttgacc ctggctaatt atttttaccg
    59401 tctcaaaaga ggtgagaagc catcagctga gcagatggac ttgtatgacc tcttggggga
    59461 tgtgaatcag gaatatgccc ttaaatatat gacaactttt ttgcttaaat tcacgcgcaa
    59521 agaccttgtg atgcaaaaac gtcctgatat atttgtggaa gctctggtta cacttggtta
    59581 cctaaaacaa gtggagccta caacatacca gctgctaatg accttggata aagaaagttt
    59641 aacctttata gcaccataga aaaaagctag gaacaaggac tgttcttagc tttttgagtg
    59701 cttttatttt gtttttacca ttaagtaaag aaaataaggg gctccgataa gcgacactaa
    59761 aatccctgtc tggatattac tgccaaccag atagactcgt cctattgtat ctgcaacaag
    59821 aagtaggatc attccgatta aaatgctaat gggtattgtt aatttatgat tactccctac
    59881 caagtatgta ctaaagtgtc cagctattaa gccgataaaa ctaatattac caaccaaaag
    59941 aacactcaaa gcacctaagc cagctgctaa gacaagtatc aaacgacgct tacggtttaa
    60001 agggagtcct agaccaatag cagtattatc agctaatccc ataatattaa ggaaatgggc
    60061 ttgactataa gtcaatagcc aaaaacacaa taataaagga gcgatgacac tcagagtagg
    60121 ccagtcgtct cctattaatt ggccgctaag ccaattgatg accaaatcga ctttgtagcg
    60181 attaatatga ccaacaagag caaccattag acttgaaagc atggtagtaa cagctacgcc
    60241 agtaagaatt aaccgtgtag aatcaatttg tccttgtttt gtcaaagata gccaataaac
    60301 gctaaaggtt gttacaacag caccaagcat ggcaaataaa ggcaagtaat ggctgatatg
    60361 agcttgctca aagaaagaaa aggagaccac aatagccaaa gagatacctg ctcctatagt
    60421 aatacctaat acaccagagt cagctaaggg atttcgtgtt aaacgttgta ataatagccc
    60481 tgataaagca agagaaccgc ctcctagaca agcagctaga attcttggca gacgaatgtt
    60541 aataacgatg aaagatatgg catggctaga ttttcccaaa aacacatgga taaggtccaa
    60601 aaaagataga tgagattctc caagggacaa agctaatccc ataagactta caagtagcag
    60661 gatcaggcta gtatataacc ccaaaaggtg tcggtgagat ttcaatagcg gcctcctctc
    60721 cttattaacc ataaaaagca tggaaaacca attaagctaa ccaatgcccc aagaggggtt
    60781 tcataaggcg gattgagatt acgacaagca atatcaaccc ataccatgaa actagcacca
    60841 gaaactgcac aaagaggcaa aaggtatcgg taatgatgag gtgtaaagtg tttcataaga
    60901 tgaggaatga ctaagccgat aaaagaaatg cttccagcaa tggctacagc tgctgatgat
    60961 aaaataagaa ccaaaatcat aaagactgca ctgatcaagt tggtcttttg cccaagagct
    61021 tttgcctgag actcacttag actaaggacg gtcaggtgat aagataatag ctgggctaaa
    61081 caaagactaa gaataataag aggagcaata tagccgatca tttgccaatt gaccccgaca
    61141 agacctcctg cttgccagcc gataacagca tttgccagat gatagtaatt ggtaatacct
    61201 tgacctaatg ctgatagcag tatggaaacc atagctcctg ctaagacaag gcggagctga
    61261 tggtagcctt tgccagattg ataagaaagg ccaaagacta aggttgctgc caggctagac
    61321 cctaacaacg aaagcagaat aatgagggaa tagtgcaagt gaggtacaaa cgcataagcc
    61381 agtaccaagg ctagtcctgc tccagcatta atgcctaaaa ggccaggctc agcgatagga
    61441 ttacgtgtga ttgcttgcat gatagttcca gaaacagcta acgcagagcc agttaaggta
    61501 gcaccaaaaa gtctcggtaa tcgtatagcg agtaaaacat tggctttatg gccgttttgc
    61561 tttccaaata aaatagagtt aagatcctga tgtgataaag caacggctcc aaagcgcaga
    61621 tgacagtaaa tagcaacaca taagctaaaa ctaagtagca caaagacaag ccaaaagata
    61681 tgtgacttag tgattatctg cgtttttttt aagcaaaaac gctcgagaca caaaaaggga
    61741 tgcttagttt tcacttgata agattgcctc tcgtaaagtc tctaattgat attctaaaga
    61801 aagaggatca gtaaagtaaa aaacattggc attgactttg atcacatggt gttttttcac
    61861 agctggaatg gattgccata gcttgctttc atatagagca gaaccagtct tatcatcttc
    61921 tgcagcaacg acgacataat caccaatata gtctggcaag acttcctgcg acaatgacag
    61981 gtaaccttgt ttaaaaactt cagtcttcac tttttcagga gcatcataat ggaaagcttg
    62041 atggataatc tctccgccac gtccccagtc tttaccaaaa aggtaaacgt ctttttcata
    62101 aagccccata atagtaaagg ttgctttgtc acctgtaacg gccttgactt ctttttcata
    62161 agctgctgtt ttagttttcc aatcttttaa ccatttcttg gctttgcctt ctttgttaaa
    62221 gatgcggccg aagtcagata acacttgtaa ataatcacgt ttgcggtatt caatcgaaat
    62281 aacaggcgca atttctgcca attgtttaat attttcttct gtagagccaa caacaatgag
    62341 gtcaggctta agcgttgtaa tggcttctaa atcagttgca gcaacttgct ttgctttttt
    62401 tacagtcttt gctaagatgg ggtttttctt gtcataagaa gtaaccccga ctagattcat
    62461 atctaatttt ttgaggtaac cagtgtaagt tgaagccaga ctgactactc gcttaggctg
    62521 tttaggaata tctccgtaat aagtcacacc agcaatttga ggcataggcg ataaactttt
    62581 tgaggcggtg ttagaatgat tagttgcttg attaccacag gcgattaagg taatagttgt
    62641 caaacagagt gttaatagta gagttaattt tttcatgtat gctaattctc ctagaataaa
    62701 gttattgaag ctgataagtc agcactatag gacagttgtg gataggatca tcaaccagta
    62761 ccggtttgat ttggaagatg tcttgaatga taggtgaagt cataacatct gctatagtac
    62821 cagtataatg gatcttgcca tgtttcatag caatcagatg atccgaatag cgggctgaaa
    62881 gattgaggtc gtgaagaacc ataataatag tcttgccggc atccttattt agggatttaa
    62941 cgagctctag gatttctagt tgatgattta aatctaaata agtagttggc tcatctaaaa
    63001 aaatagtatc agtgccttgg gctaatgcca ttgcaagcca aaccctttga cgttgccccc
    63061 cagaaagagc atcaacaggt tgatcagcat aggccatgac attggtggct tgcatagccc
    63121 aatgaatggc ttttttgtca gctggactaa gatttccaaa gtaagattga tggggaaaac
    63181 gtccgtaaga aaccaattcg taaacagtta tgccgttagt tgcttcttga acttgaggta
    63241 aaagagctag ttttttagca acctctttag tttctaatgt ggcaatgttt tgcccattta
    63301 aatacacaac tccctgtttt ggtggtaata atcttgtcag tgcttttaat aaactagact
    63361 tcccacagcc attggcgcca ataatggtcg taattttacc ttcaggaata taaaacgata
    63421 atttatcgat gatggtacgc tgttcatagg caattgtgag gtcttcagca ctaattgttg
    63481 tcatatggtt gcctcctttc taaaaagagt caaagggttg atgaaagtgc acattaaagt
    63541 attcatctgc ccattttaaa atagttgaga agtagcttat tttctcaaaa tcttcactat
    63601 tataacatag aaaaaaggct taacaaagcc ttttttgatg tgatttttag gatgtattaa
    63661 aaaagaaata ttagtttaga atgattaaaa acaatagcga taatgattct aaactaacgt
    63721 caacatactc tagaggtagt gtttggcgat tgctaaatca ccagcataag ctacttgttg
    63781 tcctttaaca atttgataag catctgcacc tttcccagcg ataatcacag catcttttgc
    63841 tccttggcaa agagacatgg ctttttgaat agcttgctca cggtcactaa taatctctac
    63901 cgggcgtgcg atatggctag caatttcttt tgaaatatct tctggatcct cgaaattagg
    63961 gtcatcagca gtgagaatga cggtgaggtt tggatgctga tgaatcaccc taccaaaatc
    64021 agctcgtctg ctctcgcctt tatttcctgg tgcacctaaa atcaacatta atttgcctgt
    64081 ctgatgttct tccacaacgc tgagtaattt ttctaagctg tcaccattat gggcataatc
    64141 aacaaaaact ttagcatgat tagtcatggt gaggacttcc atacggcctg ggacgcgagt
    64201 cttagcgata cctttttgaa tatcagctag gctagcaccc aaacgaaggc aggcaagtcc
    64261 agctgccata gcattttctt ggttaaaatg gccaattaat tgaatgtcat aatggccagc
    64321 taattgtcct ttagcttcaa aggagaaggc ttggctagtg gtgatctggt tgtcagacaa
    64381 gggaccataa aacacatgct cttgatccgc tacctgatcc gctagaaatg aaaaatgatc
    64441 catcccgcta ttgatcacaa cagctctgct attctccatt aaaagacgct tatgatagaa
    64501 ataatcttca aacgttggat gctcgattgg gccaatatga tcaggactaa tatttaggaa
    64561 aaccccaaca tcgaacgtaa gcccatagac acggtcaacg aggtaagcct gactagaaac
    64621 ttccataatc aagtgggtca tgccattagt cacacactca gccatcatag caaaaagatc
    64681 caagctctca ggagttgtga gttgtgattt gaaaaaggtc ttgccatcta aggtggtatt
    64741 catcgtagac aacaaggcag gtttatagga ttctttcaaa atatggtagg caaaataagc
    64801 agctgttgtt ttgccttttg ttccagtaaa ccctaagagc ttgagctgat cctgaggatt
    64861 accatagaaa gccatggcaa ttagactcat agcttttttg atatcagtga ccaaaacaac
    64921 gggaatacca agctcgtaat ctacctctga aatatagagt tgtaatccgt tagtgattgc
    64981 ttctttaagg tagtcagctt tgaaagttgc ccctttagca aaaaaaaggg tcttgccatc
    65041 tacttgacgg ctatcgtaac tcaagcgctc aaaactaaag ccttgataat ggtagtggta
    65101 tccgtcggca tcaagaacct cacgaaaatt atggtctttt tttaaaatgt ctaataattg
    65161 ttcaatggtt atcataccct tattttatcc ttaaagttct tgttttacaa gtcacaagca
    65221 aaagtttata ataaagctaa tagaaactag gaaagaatag atatgtcgac agaaaaaaaa
    65281 caactgacac aagaagaatt gatggttcag ggagcagcct ggtccacagc tggtaatttc
    65341 attagccgac ttttgggagt gttatacatt attccctggt atatttggat ggggcaatac
    65401 gcgattcaag ccaacgctct tttcaatatg gggtataatg tttatgctta ttttttattg
    65461 atttcaacca caggactcaa tgttgcgatt gctaagcagg ttgccaagta caattccatg
    65521 ggacaaactg agcatagcta tcaattaatc cgaagtaccc taaaactcat gcttggtctg
    65581 ggccttattt tttcagccat tatgtatctg ggctctcctt tatttgcgag cttatctggt
    65641 ggtgatgaca cacttgttcc cattatgcac agcctttctt tagcagtttt tatttttcct
    65701 gtaatgagtg tgattcgagg catctttcaa ggccacaata atatcaagcc ttatgcagtt
    65761 agtcagattg ctgagcaact cattcgggtt atctggatgc ttttgaccac cttttttatc
    65821 atgaagttgg gttctggtga ttacgcttca gcagtgactc agtcaacttt tgcagccttt
    65881 atcgggatgg tggctagtat gggtgttctg gggtactatc tttggaaaca gggacttcta
    65941 gcagctattt ttagtaagcc agatcatact gtttctattg atatcaaggg cttgttgctt
    66001 gaaaccttaa aagaatccat cccctttatc gtaacaggaa gtgccattca agcctttcaa
    66061 ttgattgatc aatggacttt tgtcaatacg atgactcttt ttacagatta tagccgttct
    66121 caattgcttg ttttatttgg ttactttaac gcaaacccag ccaaaattac aatggtctta
    66181 attgcagtag cagcatctat tggtggtgta ggtattgcct tgttaactga aaattatgtc
    66241 aaaaaagaca tgaaagcagc tgctcgttta atcattaaca acattgaaat gttagtgatg
    66301 tttttgttac ctgctcttac tggggcaatt attttagcaa gacctctata ttctgttttt
    66361 tacggagcta gcgaggagcg tgccattcac ctctttgtgg cggttctctt tcaaaccttg
    66421 ctactggcgc tttacaccct cttttcaccg atgcttcaag ctctttttga aaatcgaaaa
    66481 gcgatttact actttgccta tggtatcttg attaagttag ttttacagat accgcttatt
    66541 tatttgctac atgcttatgg tcctttacta gcgacgacga ttgctttagt ggtgccgatt
    66601 tatttgatgt atcgacgcct atatcaggtt actcatttta accgcaaact gttgcaaaaa
    66661 cgtttattat taaccttaat tgaaacctta ttaatgggac tggtcgtgtt tgtggccaac
    66721 tggctattgg gctatgcctt taaaccgaca ggccgcttga ccagccttct ttacctcctc
    66781 attattggtg gcttgggaat gacggtttac acggcactca ccttgctgac gcatcaactg
    66841 gataaattaa ttggtagcaa agctagtcgc cttcgtcaga aattaggctg gcattaatat
    66901 aatgacacca agaacgattt cgtgagtgct tatcgaaatc gtttttttct taatgatctc
    66961 gcttagtaaa ggtagctgat aaaaaatcag gatttcccaa gcaaactcct gatatttttg
    67021 gtataatgat gaaagtgtaa aaaaatagaa ggaagtatat caacatggga aaatgtcaag
    67081 ttatttcgca tccgcttatc caacacaaac tttcaatctt acgtcgtcaa accacatcaa
    67141 ctaaagattt tcgtgagttg gttaatgaaa ttgcgatgct gatgggatat gaagtgtcac
    67201 gcgaccttcc cttagaagat gtcgacatcc aaacgccagt ctcaaaaacg gtccaaaaac
    67261 agttagctgg taaaaaatta gctattgttc cgattcttcg tgctggtatt gggatggttg
    67321 atggcttgtt aagtttggta ccagctgcaa aagttggcca tatcggcatg taccgtaatg
    67381 aagaaaccct tgaacctgtt gaatacctcg ttaaactacc agaagatatt aaccaacgac
    67441 aaattttcct tgttgatcca atgttggcaa caggtggttc ggctatctta gcagtggatt
    67501 ctttaaaaaa acgtggcgca gcaaatatta agtttgtctg tttagttgca gcaccagaag
    67561 gggtgaaaaa acttcaagaa gctcatccag atattgatat cttcacagca gcacttgatg
    67621 atcatttaaa tgaacatggc tatatcgtgc caggcttggg cgatgctggt gatcgtttat
    67681 ttgggacaaa ataaaagaga caaccatcaa atagtagcct ttttaggcca atcgttcttg
    67741 attttgttta aaaaatcaga gagatttctc ttctttaaag gaaaagcaag tttatgattt
    67801 gacctttatt gaccaaaata ttataataaa gacaatcagt aaaaaagaga tgacctagtg
    67861 ggttgccgtc tctcaaaatg acgctactaa aaacccttgt agattggaga atgtattatg
    67921 attcctgttg ttattgaaca aactagccgt ggagaacgtt cttatgacat ttattcacgt
    67981 ttattaaaag accgtattat catgttaaca gggcctgtcg aagacaacat ggccaactct
    68041 gtcatagcgc agctcttatt ccttgacgcg caagacaaca cgaaagatat ctacctatat
    68101 gtcaacacac caggtggctc tgtctcagca ggcttggcta ttgtcgatac catgaacttt
    68161 atcaaggccg atgtgcaaac tattgtcatg ggtatggcag cttctatggg gacagtcatt
    68221 gcttcatcag gaacaaaagg caaacgcttt atgttaccaa atgcagagta tatgatccac
    68281 cagccaatgg gtggcacagg cggtggcacg caacaaacgg atatggctat cgcagcagaa
    68341 catctcttaa aaacacgtca ccgtttagaa aaaatcttag cgcaaaatgc tggaaaaacg
    68401 attaaacaaa tccataaaga tgctgagcgt gattattgga tgagtgctga agaaaccttg
    68461 gcttacggtt tcattgatga aatcatggaa aacaacgaac taaaataaag aggatctctg
    68521 caaaagtatt ctagaaactt ctaggatgct ttttctctta gaaaggaaaa taatgataca
    68581 gcctactgca ttaaaacagc ttcaagagtt aaaacgtcag ttcagatccc tttgcaacca
    68641 attatgagat agtttgagga tgatccttag cagctgtgtg cacgaagtta tgacgatttc
    68701 ataaaggatg acctagccag tctttcttcg tctcttttac ttaaagtgtg gtataatcag
    68761 attatgctag ccaaaattaa aaaaggcatt gccattaaag gtgttgtaga tcggcttatc
    68821 ctagatctca taacaatgct gtagtaccgc ccttaccttg ctactaaagg cgctgttgaa
    68881 gcacaaattg acttgcaaag gatcttgact gataggtata tgtccggtgg aatcgccaaa
    68941 gcagcaaaaa gaccaagacc cttatttggt ctctaccaaa atataataga aaaggattta
    69001 gaatgtttca aaaacaagaa cgtattggac tcgtcgttta cctgtattat aaccgagatg
    69061 ccagaaagtt atcaaaattt ggtgatttat attaccattc caagcgctct cgttacctca
    69121 ttatttatat taataaaaat gatttagaca caaaattaga agaaatgaga cgtttgaaat
    69181 gtgttaaaga cattagacca tcagcttttg atgatattga ccgccaattt gtaggtaacc
    69241 ttcatcgcga cgaaacaaac aaccatcaaa agggttaaca accccctagt tactgattag
    69301 cgtttcagat ttagttagct tattaaagta agaaggtttt gacagatgct cacactactt
    69361 caagacaatg agacaactag agcattagtg aataactgag ttgacggtca cttctttaat
    69421 aagaacggat aggattggtc ctaaaataga gcactgcaaa gatatgccag tgctttttag
    69481 ctcatttttt gataaaatag aactactaaa aagtgaagga aataagatga tcacaggaaa
    69541 actcataacc gttgaaggtc cagatggcgc agggaaaacg actgttttag agcaactcat
    69601 tccactgtta aaacaaaaag tggctcagga tatcttgaca acaagagagc ctggaggtgt
    69661 tgccatttca gaacacatta gagaacttat tttagacatc aaccatactg ctatggaccc
    69721 taaaacagaa ctcttacttt atattgcggc tcgaaggcag catttggtgg aaaaggtact
    69781 accagctctt gaagcaggcc agttggtttt tattgatcgt ttcatcgata gttcagtagc
    69841 ttatcaaggt gcgggacgcg gtttgatcaa agcagacatt cagtggctca acgagttcgc
    69901 aacagatggt ttagagcctg acttgaccct ttattttgat gttccttctg aaattggttt
    69961 agcacggatt aacgcgaacc aacaaagaga agtcaatcgt ttagatttgg aaacaataga
    70021 gatacatcaa cgagtacgaa aaggatacct agccttagct aaggagcatc caaaacgtat
    70081 tgtcacaatt gatgcgacta aaccattgaa agaagttgtc tctgtcgctt tggaacatgt
    70141 cttagccttg cttttagcct aggataaggg agggtaggaa tggatttagc gcaaaaagct
    70201 cctaacgttt atcaagcttt tcagacgatt ttaaagaaag accgtctgaa tcatgcttat
    70261 cttttttcgg gtgattttgc taatgaagaa atggctcttt ttttagctaa ggtcatcttt
    70321 tgtgaacaga aaaaggatca gacgccctgc gggcattgtc gctcttgtca attgattgaa
    70381 caaggagatt ttgccgatgt gacggtattg gaaccaacag ggcaagtgat taaaacggat
    70441 gtggtcaaag aaatgatggc taacttttct cagacaggat atgaaaacaa acgacaagtt
    70501 tttattatca aagattgtga caaaatgcat gtcaatgccg ctaatagctt gctaaagtat
    70561 attgaggagc ctcagggaga agcttacata tttttattga ccaatgatga taacaaagtg
    70621 cttccgacca ttaaaagtcg gacacaggtt tttcagtttc ctaaaaacga agcctatctt
    70681 taccaattgg cacaagaaaa gggattatta aaccatcagg ctaagctagt agccaaactt
    70741 gccacaaaca ccagtcatct agaacgtctg ttgcaaacga gcaagctttt agaactgata
    70801 actcaaacag agcgttttgt atctatttgg ctgaaagatc agttgcaggc atatttagcg
    70861 ttgaatcgtc tggtacagtt agcaactgaa aaagaagaac aagatttagt tttgaccctt
    70921 ttgaccttgc tcttggcaag agagcgtgcg caaacgcctt tgacacaatt ggaggctgtt
    70981 tatcaggcta ggctcatgtg gcagagcaat gttaatttcc aaaacacatt agaatatatg
    71041 gtgatgtcag aataagtgca attggaattc gttatgggga aacgaagctt gtcaaaagac
    71101 ttgcccgtag cgaccaaagt agcggcgcat aggggcaaaa aagcttttga agaaaatact
    71161 gcctttgcaa cagatttgat gaaagaagta tcacgattaa taacacaaaa taaacttgaa
    71221 atgacgttta ttaatagtgt ctttctctta gatcagcatg ttgtcctaat tcccttttca
    71281 gcagaagagc acatggattt ttacaactgt taaaagattt agcggccgat tttaggtcaa
    71341 gaagtgagct gccccagatt aacagccaag aagaaaccaa gatttatggg cgcttaggac
    71401 cgtgtggcag accactgtgc tgctttcgtt tttgggaaaa tttctgacag tatctattaa
    71461 aatactaaaa aatcaagggt tatcattgac tttgggtaaa gcaacaagcc cttatggccg
    71521 tttgctttgc tgtctctatg atgaaggtgt cttttaccaa taaagcaaga aaaaattccc
    71581 tgaatatggt accatagtag agacaagtga tggccctgca acagtagcag ccttgatata
    71641 tttacagatc ccattaaggt gcggttaaaa gaccagttga ccttagtcac ttatgcttta
    71701 gaggaggtta aagtaggtga ataaaaaaga attattcgat gcttttgatg gattttccca
    71761 aaatttaatg gttactttag ctgaaattga agccatgaaa aaacaagtcc aatcactagt
    71821 agaagaaaac acgattcttc gcctagaaaa tacaaaacta cgggaacgtt tgagtcacct
    71881 agaacatgaa acggtagcta aaaatccttc caaacaaagg aaggatcact tagagggaat
    71941 ttatgatgaa gggtttcata tctgcaattt tttctatgga caacgtcgtg aaaatgatga
    72001 agaatgtatg ttttgcagag aattattaga tagaaagtaa gggcatgcag gttcaaaaaa
    72061 gttttaaaga caaaaaaaca agcggaacct tgtatttggt tccaaccccg attggcaatc
    72121 tgcaggacat gacctttaga gcagtggcaa cgttaaaaga ggttgatttt atttgtgcag
    72181 aagacacaag aaacacaggt cttttgctaa aacactttga cattgctacc aagcaaatca
    72241 gctttcatga gcacaacgcc tatgagaaga ttcctgattt aattgattta ttaatatcag
    72301 gacggtcatt agctcaggtg tctgatgcag gaatgccatc gatttctgat cctgggcatg
    72361 atttggtcaa ggctgctatt gatagtgata tcgcagtcgt tgctttacca ggtgcctcag
    72421 ctgggattac agctttgatt gctagtggac tggctcctca accccatgtt ttttatgggt
    72481 ttttacccag aaaagcaggg caacaaaagg ctttctttga ggacaaacac cattacccag
    72541 agacacaaat gttttatgaa tcaccctatc gcatcaaaga taccctgacc aatatgttgg
    72601 cttgttatgg tgatcgtcaa gtggtgcttg ttagagaatt aaccaagctt tttgaggagt
    72661 accaacgggg gtcgatttca gaaatcttgt cctaccttga agaaacaccc ctaaaagggg
    72721 agtgtctgct gattgtggct ggagcccaag tagacagtga ggttgagctg acagctgatg
    72781 ttgacttagt gtctctagtg caaaaagaaa tccaagcagg agccaagcca aatcaggcta
    72841 ttaaaacaat tgctaaagct taccaggtaa atcgccaaga gctttaccaa caatttcatg
    72901 acttataagt catcgtagat taggagaaaa acaaatgaca gaagatcaag caactatcct
    72961 tattttagga gtatacggaa ttatattggc tgtattctta ctatcagctt tattatgcct
    73021 tatcgctaac tggcgactct ttaaaagagc aggttacaaa ggatggtata gtctcattcc
    73081 tttctatgca ggttttgtca aacacaaaat cacttttgga gaagataata aatggtttta
    73141 ctttattggt tgggtcattg ctatttatta ttactatgtg cacttttgct atgtccgtgc
    73201 ttttggtgga tcaaagggtc tagcagtatt tggcttgttt ttcccaggca ttgcttcttt
    73261 gatagtggct tttggaaaaa cttataccac acaagaatgc caccctgtgc cacatctttt
    73321 aaactaagag aaaaaagacc atcaattgga tttattgatg gtcttttagg tgtttaaatg
    73381 attttagtcc cgtgaacaat ggccgttcca gtgagttgac tcaagctttg gcaattctca
    73441 gcagtgacgc ctcctccaat catgatgtca atgcgtttat tggcataggt cacaagactt
    73501 ttaagctgtt ccacattgtc tgtaatagga gtagcttcag gggagccatg agttagcaca
    73561 cgcacaaagc cataatcaat cagttggtca agcgcttggt gctggtgatc agtcggaata
    73621 tggtcaaaag ccatgtggaa aaccagtggc aagccttgtg tagcaggtag taattgctcg
    73681 atagcgtcgg tatccagttg attttccgaa gtcagcaggc ctaacacaag cgcatcagag
    73741 ccagcttcaa cagcttttaa gatatcttct tccatagctt ttagttcgag gtcgttatag
    73801 acaaaatcgc caccgcgagg tcgaatcatg gttgctacac tgatgttttt atcgtgtaaa
    73861 agctggcagg cttctttgat gacaccgtaa gatggcgtgg tccctccgac agctaggtta
    73921 tcacagagtt ccacacgact gacttgacca gcatcaaggg ttggcagtag tgtgaggttc
    73981 tcagcacaaa attctttaat catttttaga tctcctttat cactaatatt atagcacgaa
    74041 tgaagctagt catcaggaaa catttttgtc aaatcatgga cattatgcta tactcactag
    74101 tattaaaagt aggccaaaat agcagcaaat actttgaaaa aagattgcta tgttctacgg
    74161 caatatcagt ctttaccaac gaactctcaa gaagaaaaga aagacaaagc ttagcatttt
    74221 aaaaaagccc cccctttttt tgtgaaatga tgaccaaaaa caggcgcccc acgcctaaaa
    74281 cagttaccct aaaggaaaag gagaaaaaat gattacgatt taccaatacc caaaatgtag
    74341 cacctgccaa agagccatgg ctgaattaaa gcaactggtt agtgactttg aagccattga
    74401 catcaaagct aatccaccca aagctcagga cctcaaacat tggatggaaa catctggtta
    74461 taccatcaaa aatttcttta ataccagtgg taacagctac cgcgaattgg gacttaaaga
    74521 taaaatagac cagcttagcc ttgataaagc tgctgaactc ttagccacag atggtatgct
    74581 gattaaacgg cctattctga ttaaggatgg taacgtctta caagttggct atcgcaagcc
    74641 atatcaagag ttggatttag gataatgcga caaagtctca aaaaaggaca aggcaacatt
    74701 ataacgcctt gtcctttttt gggatctgtt tttagacatt agagatcaat atctagtaaa
    74761 attggcgtat ggtcttggcg ttccccagaa gaaatcattt cagaacgctt aaccttatcc
    74821 acaagtcggt ttgaagctag ccaatagtca attctccaac cggtattatt gattttgctg
    74881 gttttgctac gttgtgccca ccaggtataa acatgaggaa tatcgccgtg cacgtgacga
    74941 aaagtatctg taaagcctct tgctaatagg ttagtaaagc cttgacgttc ttcgtcggta
    75001 aaaccagggg aacgtcgatt gctgcttgga tttgccaaat caatctcttt gtgggcaacg
    75061 ttgtaatctc ccgtagccaa aacaggcttt tgagcatcca gttcagtcaa gtaatcagcg
    75121 tatttgtggt cccaaatttg acggtcatct aaacgtctaa ggccatcacc agcattaggc
    75181 gtgtaaacct gtgtgacgaa aaagtcttca aattctaggg taatgatacg gccctcagca
    75241 tccattgttg ttggggcacc aatttctgga aaagtaatga cagggtttag cgtgtttttg
    75301 tacaggaaca tggtgccagc atagcctttc ctagcaggct caactgaaga acgccacaca
    75361 cgcaaatagt ttggaaagta actaagtaag gcctcgatat gttttttggt aggcccctta
    75421 gcagataatt tggtttcttg aatggcaata atatccgcat cttgagcgac taaagtgtct
    75481 aaaacagcgc gtgataaaag cgcacgaggg gactctcctg tgagagcagc atttaaggaa
    75541 tcaatgttcc atgaaatcag tttcatttgg tatctctttc taacagatag tcttgttgtt
    75601 attgtaacaa aaaacgaaac gataagcgac tttgggcatc tagcccccat aaaacagtct
    75661 agccaaatga agcatagcag cgtaagaaca agacaaggag gtgatcagtg agcatatcgt
    75721 ttgacagtta agagtaggat tactataata gaagcataaa tgtaagcgct aacaaaataa
    75781 aaaatatagg agaatgtcaa tggcacaaaa aacagtcatc accgaagaaa caaccgattt
    75841 tgttatggat ttcaaaacaa gtagcgctga gggaaatgtt gattttatta acgtttttga
    75901 ccttgagaaa atggcacaac aggtcatccc taaaggagcc tttggttata ttgctagtgg
    75961 tgctggtgat acctttaccc tccatgaaaa tattcgctca tttaatcata aattaattgt
    76021 ccctcactcc ctcaaagggg ttgaaaatcc gtcaacagag attacgtttg atggtgatca
    76081 cttaacctct cctcttattt tagcacctgt agcggctcat aagctggcca atgaacaagg
    76141 agaagtagcg tctgccaaag gattgaagga atttggaagt atctacacca ctagttccta
    76201 ctcaacaact gacctgccag aaatcagtgc tgccttaggt gggacacccc attggtttca
    76261 attttattac agtaaagacg atggcattaa tcgtaatatt atggatcgtg tcaaagcaca
    76321 aggttgcaaa gctatcgttt tgacagcaga tgcaacagtt ggaggaaacc gcgaagttga
    76381 taggcgaaac ggttttgttt ttccggtcgg tatgccaatt gttcaagaat atttacctga
    76441 tggtgcaggt aaaacaatgg attatgtcta taaatcagct aaacaagcgc ttacctcaaa
    76501 agatattgaa tatatcgcaa cttactcagg cctgcctgtt tatgtcaaag gaccacagtg
    76561 tgctgaggat accttgcggg cattggacgc aggagcatca ggtatctggg taaccaatca
    76621 tggtggccgt caattagatg gtggtccagc tgcttttgat tccttacaag aagtcgctga
    76681 agcagttgat caaaaagttc ctattgtctt tgactcaggt ataagacggg gtcaacatat
    76741 tttcaaagct cttgcttcag gtgctgacct tgttgccttg gggcgtccag cgatttacgg
    76801 cttggctatg ggaggaagca ctggtactcg tcaggtcttt gaaaagttaa atgacgagtt
    76861 aaaaatggtc atgcaactgg ctgggacaca gactatccaa gatgttaaag cctttaacct
    76921 tcgccataat ccgtatgatt catcgattcc atttgatcaa aatgcgttac gcttagatta
    76981 gaacagacaa aaacctccgc tatcatgtca caaatagtag aggttttaca ctgcaaaaag
    77041 aggtatgaaa attcaataac atagttacaa ggctatcgtt taccaccccc cactaataga
    77101 ttaaaatgaa agacttctta cattaataga aatttctgtt gcttttctca gaaaaatgtg
    77161 gttaaataat caaatattat taacgaaaaa tgagttaatg attaacatta aactggtttt
    77221 agttaaaaca tttaggaggg tatcaggtgg agaaaaagca acgtttttcc cttagaaaat
    77281 acaaatcagg aacgttttcg gtcttaatag gaagcgtttt cttgatgatg acaacaacag
    77341 tagcagcaga tgagctaacc acaacgagtg aaccaacaat cacgaatcac gctcaacaac
    77401 aagcgcaaca tctcaccaat acagagttga gctcagctga atcacagtcc ccagacacat
    77461 cacaaatcac tctcaagaca aatcgtgaaa aagagcaatc acaaggtcta gtctctgagc
    77521 caaccacaac tgagctagct gacacagatg cagcaccaat ggctgataca ggtcctgatg
    77581 cgactcaaaa aagcgcttct ttaccgccag tcaatacaga tgttcacgat tgggtaaaga
    77641 ccaaaggagc ttgggacaag ggatacaaag gacaaggcaa ggttgtcgca gttattgaca
    77701 cagggatcga tccggcccat caaagcatgc gcatcagtga tgtatcaact gctaaagtaa
    77761 aatcaaaaga agacatgcta gcacgccaaa aagccgccgg tattaattat gggagttgga
    77821 taaatgataa agttgttttt gcacataatt atgtggaaaa tagcgataat atcaaagaaa
    77881 atcaattcgg ggattttgat gaggactggg aaaactttga gtttgatgca gagccaaaag
    77941 ccatcaaaaa acacaagatc tatcgtcccc aatcaaccca ggcaccgaaa gaaactgtta
    78001 tcaaaacaga agaaacagat ggttcacatg atattgactg gacacaaaca gacgatgaga
    78061 ccaaatacga gtcacacggt atgcatgtga caggtattgt agccggtaat agcaaagaag
    78121 ccgctgctac tggagaacgc tttttaggaa ttgcaccaga ggcccaagtc atgttcatgc
    78181 gtgtttttgc caacgacgtc atgggatcag ctgaatcact ctttatcaaa gctatcgaag
    78241 atgccgtggc cttaggagca gatgtgatca acctgagtct tggaaccgct aatggggcac
    78301 agcttagtgg cagcaagcct ctaatggaag caattgaaaa agctaaaaaa gccggtgtat
    78361 cagttgttgt agcagcagga aatgagcgcg tctatggatc tgaccatgat gatccattgg
    78421 caacaaatcc agactatggt ttggtcggtt ctccctcaac aggtcgaaca ccaacatcag
    78481 tggcagctat aaacagtaag tgggtgattc aacgtctaat gacggtcaaa gaattagaaa
    78541 accgtgccga tttaaaccat ggtaaagcca tctattcaga gtctgtcgac tttaaagaca
    78601 taaaagatag cctaggttat gataaatcgc atcaatttgc ttatgtcaaa gagtcaactg
    78661 atgcgggtta taaagcacaa gacgttaaag gtaaaattgc tttaattgaa cgtgatccca
    78721 ataaaaccta tgacgaaatg attgctttgg ctaagaaaca tggagccctg ggagtactta
    78781 tttttaataa caagcctggt caatcaaacc gctcaatgcg tctaacagct aatgggatgg
    78841 ggataccatc tgctttcata tcgcacgaat ttggtaaggc catgtcccaa ttaaatggca
    78901 acggtacagg aagtttagag tttgacagtg tggtctcaaa agcaccgagt caaaaaggca
    78961 atgaaatgaa tcatttttca aattggggcc taacttctga tggctattta aaacctgaca
    79021 ttactgcacc aggtggtgat atctactcta cctataacga taaccactat ggtagccaaa
    79081 caggaacaag tatggcctct cctcagattg ctggcgccag ccttttggtc aaacaatacc
    79141 tagaaaagac tcagccaaac ttgccaaaag aaaaaattgc tgatatcgtt aagaacctat
    79201 tgatgagcaa tgctcaaatt catgttaatc cagagacaaa aacgaccacc tcaccgcgtc
    79261 agcaaggggc aggattactt aatattgacg gagctgtcac tagcggcctt tatgtgacag
    79321 gaaaagacaa ctatggcagt atatcattag gcaacatcac agatacgatg acgtttgatg
    79381 tgactgttca caacctaagc aataaagcca aaacattacg ttatgacaca gaattgctaa
    79441 cagatcatgt agacccacaa aagggccgct tcactttgac ttctcgctcc ttaaaaacgt
    79501 accaaggagg agaagttaca gtcccagcta atggaaaagt gactgtaagg gttaccatgg
    79561 atgtctcaca gttcacaaaa gagctaacaa aacagatgcc aaatggttac tatctagaag
    79621 gttttgtccg ctttagagat agtcaagatg accaactaaa tagagtaaac attccttttg
    79681 ttggttttaa aggacaattt gaaaacttag cagttgcaga agagtccatt tacaggttaa
    79741 aatctcaagg caaaactggt ttttactttg atgaatcagg tccaaaagac gatatctatg
    79801 tcggtaaaca ctttacagga ctcgtcactc ttggttcaga gaccaatgtg tcaaccaaaa
    79861 cgatttctga caacggtcta cacacacttg gcacctttaa aaatgcagat ggcaaattta
    79921 tcttagaaaa aaatgcccaa ggaaaccctg tcttagccat ttctccaaat ggtgataaca
    79981 accaagattt tgcagccttc aaaggtgttt tcttgagaaa atatcaaggc ttaaaagcaa
    80041 gtgtctacca tgctagtgac aaggaacaca aaaatccact gtgggtcagc ccagaaagct
    80101 ttaaaggaga taaaaacttt aatagtgaca ttagatttgc aaaatcaacg accctgttag
    80161 gcacagcgtt ttctggaaaa tcgttaacag gagctgaatt accagatggg tattatcatt
    80221 atgtagtgtc ttattaccca gatgtggttg gtgccaaacg tcaagaaatg acatttgaca
    80281 tgattttaga ccgacaaaaa ccggtactat cacaagcaac atttgatcct gaaacaaacc
    80341 gattcaaacc agaaccccta aaagaccgtg gattagctgg tgttcgcaaa gacagtgtct
    80401 tttatctaga aagaaaagac aacaagcctt atacagttac gataaacgat agctacaaat
    80461 atgtctcagt agaagacaat aaaacatttg tggagcgaca agctgatggc agctttatct
    80521 tgccgcttga taaagcaaaa ttaggggatt tctattacat ggtcgaggat tttgcaggga
    80581 acgtggccat cgctaagtta ggagatcacc taccacaaac attaggtaaa acaccaatta
    80641 aacttaagct tacagacggt aattatcaga ccaaagaaac gcttaaagat aatcttgaaa
    80701 tgacacagtc tgacacaggt ctagtcacaa atcaagccca gctagcagtg gtgcaccgca
    80761 atcagccgca aagccagcta acaaagatga atcaggattt ctttatctca ccaaacgaag
    80821 atgggaataa agacttcgtg gcctttaaag gcttgaaaaa taacgtgtat aatgacttaa
    80881 cggttaacgt atacgctaaa gatgaccacc aaaaacaaac ccctatctgg tctagtcaag
    80941 caggcgctag tgcatcagct attgaaagta cagcttggta tggcataaca gcccgaggaa
    81001 gcaaggtgat gccaggtgat tatcagtatg ttgtgaccta tcgtgacgaa catggtaaag
    81061 aacatcaaaa gcagtacacc atatctgtga atgacaaaaa accaatgatc actcagggac
    81121 gttttgatac cattaatggc gttgaccact ttactcctga caagacaaaa gcccttggct
    81181 catcaggcat tgtccgcgaa gaagtctttt acttggccaa gaaaaatggc cgtaaatttg
    81241 atgtgacaga aggtaaagat ggtatcacag ttagtgacaa taaggtgtat atccctaaaa
    81301 atccagatgg ttcttacacc atttcaaaaa gagatggtgt cacactgtca gattattact
    81361 accttgtcga agatagagct ggtaatgtgt cttttgctac cttgcgtgac ctaaaagcgg
    81421 tcggaaaaga caaagcagta gtcaactttg gattagactt accggtccct gaagacaaac
    81481 aaatagtgaa ctttacctac cttgtgcggg atgcagatgg taaaccgatt gaaaacctag
    81541 agtattataa taactcaggt aacagtctta tcttgccata tggcaaatac acggtcgaat
    81601 tgttgaccta tgacaccaat gcagccaaac tagagtcaga taaaatcgtt tcctttacct
    81661 tatcagctga taataacttc caacaagtta cctttaagat gacgatgtta acaacttctc
    81721 aaataactgc ccactttgat catcttttgc cagaaggcag tcgcgttagc cttaaaacag
    81781 ctcaaggtca gctaatcccg cttgaacagt ccttgtatgt gcctaaagct tatggcaaaa
    81841 ccgttcaaga aggcacttat gaagttgttg tcagcctgcc taaaggctac cgtatcgaag
    81901 gcaacacaaa ggtgaatgcc ctaccaaatg aagtgcacga actatcatta cgccttgtca
    81961 aagtaggaga tgcctcagat tcaactggcg atcataaggt tatgtcaaaa aataattcac
    82021 aggctttgac agcctctgcc acaccaacca agacaacgac ctcagcaaca gcaaaagccc
    82081 taccatcaac gggtgaaaaa atgggtctca agttgcgcat agtaggtctt gtgttactcg
    82141 gacttacttg cgtctttagc cgaaaaaaat caaccaaaga ttgataacaa aacgcaaaga
    82201 gacaacaaat catccctttt aacagtctga cctttctttg agattgagct ggcagatgat
    82261 catttcttaa caaaagttaa agagttgagc aaagtaagga acagacataa acaccataaa
    82321 agcaagccag tttggcttgc ttttatggtg ttattgtcgt gtgctacgat gactaaaaaa
    82381 gaacaacgaa caatgacctc gaatcaccaa aaggacttga tttgatagct tccctatgct
    82441 atactaagcc tattctttca agaaggactc cttttgtgga aaagactgaa aaaaaggaca
    82501 ctaatctatc caaaaactcc agataggtag ctgcaaacgg atgcctctgc tgtgatcaag
    82561 gtggtaaagc agactgactt gtcactatct gagcaggtgt caaaaaaaga agctttggct
    82621 ttgtcattca acatactgag cttcagtctt tcagaacgga gacaccccca gttttgtact
    82681 caaaaagcat aaacagctct gctgatgtga catccgattt ctacgtgcgc agtgagccaa
    82741 aacagctgct gtttgctatg gaaaaagtgg cgccaatcga gatttttgag accctaggct
    82801 caaaaataag gcatagaatt ccaaaggaag tcgctgccgt gagcacaacc taagaaaaac
    82861 tatcccaaaa gactttttct gcaatttgaa atactgaatt tcagtatttt ttcttttgta
    82921 actaagagca atgaatgagg taaaaaaagg caacaatgtc aaaaaagaaa cgaaaacact
    82981 atcaggttta tgagggatta cgctgtgcta tgacgctttg ttttatcagt ggctatgtca
    83041 atgcctttac ctatatgaca caaggcaaac gttttgcagg tgttcagaca ggcaaccttt
    83101 tgtcatttgc cattcgcttg tcagaacagc aactgaagga ggcactgcaa tttttacttc
    83161 ccatgatcgt ttttatgctt gggcagtcct ttacttattt catgcaccgc tgggccacta
    83221 aaaagggtct ccactggtac ctcttatcaa gcgttatgtt aacaggactt gcttttggaa
    83281 cggccctatt cacgcctttt cttccttcca atgttacggt agcagcttta gccttttttg
    83341 cctctattca ggttgatacg tttaaaacct tacgaggagc tagctatgct aatgtgatga
    83401 tgacaggaaa tatcaaaaat gccgcctatt tactaaccaa aggcttgtac gaaaaaaatc
    83461 acgaactaac acatatcgga cgcaacacct taatagtcat cttggctttt gctgttgggg
    83521 tggtttgttc gacgttgctt tgcatagctt atggtgagta tgctttgatg cctattttaa
    83581 tgcctttact ctatgtcaat tacctgttgg ctcaggaatt ttatcacatt caaaccaaaa
    83641 tcaaaccgat taaaagaact taatggactt gtagagaaag aaagttcatt tagggtaagt
    83701 ttttactcac cctcctttga ttgactggtt ttgctgcccc ttaaaatatg atataataga
    83761 ccattgatag ctgttactta acagaaggct gataaaaaag gttccattag ccttgagggt
    83821 tgaatttaaa caggaaaaaa cgaaatccta cactatgtat ctcaatcgta ctttcatttg
    83881 agtatggttc tgaaaggaaa ctatgatgaa aaaaccattt tacattacga cacccattta
    83941 ttacccatct gggaaattac acattggttc tgcctataca actattgctt gtgatgtctt
    84001 ggcacgctac aagcgcttga tgggccatga ggtcttttac ctcacaggac ttgatgagca
    84061 cggacaaaag attcaaacca aggcaaaaga agctggtatt acacctcaaa cctacgttga
    84121 taacatggca aaggatgtca aagccctttg gcaattgcta gatatttcct atgacacatt
    84181 tatccggaca acggacgatt accacgaaga ggtcgttgct gctgtctttg aaaaattgct
    84241 ggcgcaagac gacatttacc ttggcgaata ctctggttgg tattctgtct ctgatgagga
    84301 atttttcact gaaagccaat taaaagaagt ctttagagat gaagacggtc aggttattgg
    84361 ggggattgcc ccatcaggtc atgaggtcga gtgggtctct gaagaatcct atttcctacg
    84421 ccttagcaaa tacgctgatc gtcttgtggc cttctttaaa gagcgacctg actttatcca
    84481 accagacggt cgtatgaatg aaatggtgaa aaactttatc gagccaggtc tagaagattt
    84541 ggcagttagc cgtactacct ttacatgggg tgtacctgtt ccatcagacc caaaacacgt
    84601 ggtttatgtc tggattgatg ccctcttaaa ctacgcgaca gctcttggtt atggtcaagc
    84661 taatcacgct aactttgata agttttggaa tggaacggtt ttccacatgg ttgggaaaga
    84721 tatcttgcgt tttcatagca tctactggcc aattttactc atgatgcttg atttaccaat
    84781 gccagaccgc ttaattgccc atggttggtt tgtcatgaaa gacggtaaaa tgtctaaatc
    84841 aaaaggcaat gtggtctatc cagaaatgtt agtggagcgc tttggacttg atcctcttcg
    84901 ttattacctc atgcgttctt tgccagttgg ttcagacggg acctttaccc ctgaagatta
    84961 tgtgggtcgt atcaactatg aattggccaa cgatcttggt aatttattga atcgtaccgt
    85021 tgcgatgatc aacaagtatt ttgacggcac ggtgccagct tatgttgaca atggaactgc
    85081 ctttgatgct gacttaagtc aactgattga tgctcagcta gcagactacc ataaacacat
    85141 ggaagctgta gactacccac gcgccttaga agccatttgg accatcatcg ctcgtaccaa
    85201 caaatacatc gatgaaaccg ctccttgggt gctcgctaaa gaagatggtg acaaggctca
    85261 actagccagt gtcatggcac acttggcagc tagcttgcgc gtggtcgctc atgtgatcca
    85321 accctttatg atggaaacat cagctgctat catggcccag cttggcttag cgcctgtttc
    85381 tgacttgtca acacttgctc tagcagattt tcctgccaat acaaaggtcg ttgccaaagg
    85441 gacaccgatt ttcccacgtc ttgacatgga agctgagatt gactacatca aagcccaaat
    85501 gggtgacagc tcagctattt cccaagaaaa agaatggatc cctgaagagg ttgcactcaa
    85561 atctgaaaaa gacgtcatca catttgaaac ctttgatgct gtggaaatcc gtgtggcaga
    85621 agtcaaggaa gtgtcaaaag tggaaggttc agaaaaattg ctgcgcttta gagtagatgc
    85681 aggagacggg caagaccgtc aaatcttgtc aggtattgcc aaattttacc ccaacgaaca
    85741 agaattagtg ggcaaaaaac tacaaattgt tgctaacctg aaaccgcgta aaatgatgaa
    85801 aaaatacatc agtcaaggga tgattctatc agcagagcat ggagatcaac taacggtctt
    85861 aaccgttgat tcctctattc caaatggaag tatcattggc tgatgctgac ctattattca
    85921 aaaaacctaa gcaagaacat gtgcttaggt ttttttgatt gccttcaaga aagacgaata
    85981 acgagatggg tgatatggca tcaaaagcat aactatccta ggacctgtcc tagtaagatt
    86041 gctgtgcttt tgacaagtga acagagaggt cttaaaacta tatcttgtca taaaaaagat
    86101 tgcaaaacac tatatcttgt gttattatgg tttttataaa agttaagtat gcttaacttt
    86161 agccaaacaa aagaggacac tagagccgtg tcccacaaga cagttgagcc cttcgctttt
    86221 ttagtagagt aggagtgctc aagtcaaaaa gagacatccc atcaaaccat tgctgtttag
    86281 caggtctttt tgtgttgctc aaaaaaacaa ttcctgtctg tttggcgtct agtgatgact
    86341 taggcttagc gctactagac ttttgtttga aaaatacctc aagccttgaa ggagacaaat
    86401 gacccaacat tattatgaac gttcgcaatc cccaattgaa tacgccctat ctgaaacaca
    86461 aaaacagttg cgttccatca attggaatta ccttaatgat gacaaagatt tggaagtgtg
    86521 gaaccgtgtc actcaaaatt tttggttgcc tgaaaaggtt cctgtttcta atgatttaaa
    86581 ttcttggcgc tccttgggtg aggattggca acagctcatc acaaggacct acactgggtt
    86641 gaccttacta gatacagtac aagcaacggt tggtgatgtg gcacaaattc agcattcaca
    86701 aaccgaccac gaacaagtca tctatacgaa ctttgccttt atggtgggga tccatgcccg
    86761 ctcttacggg acgatttttt cgaccctttg cagcagcgag caaatcgaag aagcacatga
    86821 atgggtggtc tcaacacaga gcttgcaaga ccgtgcccgt gtcttgattc cttactatac
    86881 gggtgatgac cctttgaaat caaaagtagc agcagctatg atgccaggat ttttgctgta
    86941 tggcggcttt taccttcctt tctacctatc agcacgtggt aaaatgccaa acacatctga
    87001 tatcatccgc ctgattttac gcgacaaagt tattcacaac tattacagcg gttacaaata
    87061 ccaacaaaaa gtagcacgtc ttagcccaga aaaacaggct gaaatgaagg cctttgtctt
    87121 tgatttgctc tatgaactca tcgaccttga aaaagcttac ttgagagaac tgtatgcagg
    87181 ctttgatttg gcagaagatg ctatccgttt tagcctttat aacgctggaa aattccttca
    87241 aaatttaggc tatgagtcgc ccttcacaga tgaagaaacg cgcgtttcac cagaagtatt
    87301 tgctcagcta tcagcgcgtg cagacgaaaa ccatgacttt ttctcaggca atggctcatc
    87361 ttatgtgatg gggatcaccg aagaaaccac agatgacgat tgggagtttt aaaaaatggc
    87421 agagctgatt attgtgtatt tttcatctaa gtccaataac acccatcgct tcgtccaaaa
    87481 attaggcctg cctgctcagc gcataccagt agataatagg ccacttgaag tttccaccca
    87541 ttaccttttg attgtgccta cctatgcagc tggtggctca gatgccaaag gagccgttcc
    87601 taaacaagtg attcgttttt tgaataaccc taacaatcgt aaacattgta agggagtgat
    87661 ctcttcagga aataccaatt ttggcgatac ctttgcctta gcaggcccta tcatttctca
    87721 aaaattgcag gtccccttat tacaccaatt tgaactatta ggcactgcta cagatgtcaa
    87781 aaaggtccag gcgatttttg cccgcttaaa gcatcacaca cacgacaagc aaaaacaaac
    87841 caacaacctg attacagaaa ggacacaccc atgtcacaaa ccaatgcgtc atacctctca
    87901 ttaaatgcac tgactcgttt taaaaaaaca gacggcagct accattttga tagcgataaa
    87961 gaagctgtta ggcgctacct ggaagaacac gtctcaccca atcaaatggc ttttaactca
    88021 ctagaagata agctagctta cctcatcaat gaagggtatt atgagcaggc catttttgat
    88081 gcctatccta acgaccttat caaggaggcc tttcattatg cctatcaaca aggctatcgc
    88141 tttttaaatc tcatgggcgc tatgaaattt taccagtcct atgccttaaa aaccttggac
    88201 ggtaagcatt atctagaaac atttgaagac cgtgctgtga tgaatgcact ctttttagct
    88261 gatggagatc aaacctttgt ctttgacgtg attgatgcca tcttgcaccg acgctttcaa
    88321 ccagccaccc caacgttttt aaatgccgga aaaaaacgcc gtggcgaata catttcgtgc
    88381 taccttcttc gtgtcgaaga caatatggaa tctatctctc gcgccattag caccagcttg
    88441 caactttcaa aaagaggagg cggagtcgcc ttgtgcctca ccaacctcag agaaatcgga
    88501 gcaccgataa aagggattga aaatcaggca acaggcatcg ttcctgtcat gaaactacta
    88561 gaggactctt tttcctatgc caatcaacta ggtcagcgcc aaggagcagg tgcggtttac
    88621 cttcatgccc atcatcctga ggttttgacc tttttagata ccaaacgtga aaatgccgat
    88681 gagaaaattc gcattaagtc cctagcattg ggacttgtga tcccagatat taccttccag
    88741 ttagccaaag aaaacaaaga catggcactc ttttcaccct atgatatcaa gcgtgcctat
    88801 ggcaaggaca tgtcagacat ctccatcaca gaggaatacg ataaactgct agccaatcca
    88861 gccatcaaaa aaacctacat cagtgctaga aagttctttc agttaattgc agagctacat
    88921 tttgagtcag gctaccctta cctcttgttt gatgacacgg tcaataagcg caaccctcat
    88981 gccaaaaaag gcagaatcgt catgtctaac ctgtgttctg aaatcgctca agtcagcacc
    89041 ccaagcactt tcaaagaaga tttgagtttt gaaaccattg gagaagatat ctgctgtaat
    89101 ttagggtcta tcaatattgc ccaggctatg gcagatgcgc cacactttga acagctcatc
    89161 acaacgagca tcagagcact tgatcgtgtc tctagagtgt ctgacctgaa ttgtgcgcct
    89221 tctgttgaga caggcaatgc agccaaccat gcagtaggat taggcgccat gaacctacat
    89281 gggtttttgg caaccaacca catctactat gatacaaaag aagccgttga ctttacagat
    89341 ctgtttttcc atgccatggc ctattatgct tttaaagcct cttgccaatt agccaaagaa
    89401 aaaggcgctt tcgcaggatt ttcgttatca acctatgcag atggcactta ttttgccaag
    89461 tatttgcaag aagatgccaa gccacaaaca gccaaggttg ccacattgtt gcaagattac
    89521 ggcttcacat tgccaacggt ggcggactgg caatccctag tagcggatat caagcagttt
    89581 ggcctagcca atgcgcactt gctagcggtt gctccgacag gctctatcag ctacttatca
    89641 tcctgcactc cgagtctaca accagtcgtt gctcctgttg aggtccgaaa agaaggtagc
    89701 ctgggcagga tttacgtccc tgcctatcag attgaccagg ctaactatgc ttactatgaa
    89761 cgtggtgcct atgaggtcgg cccaaaagcc atcatcgacg ttgtcgctgc tgcccaaaaa
    89821 cacgttgacc aagccatctc attgaccctg tttatgaccg atcaagcgac cacacgtgac
    89881 ctgaaccgct cctatatcca agcttttaag caaaactgtg catcgatcta ttatgtgcga
    89941 gtgaggcaag acgtcctagc aggcagcgaa cagtatgacg aggatagtct tgtgacagct
    90001 cctggagcta gtgatgagac caccacagag tgtcaaagct gtatgatcta acagctacta
    90061 gaaagctctc gtgtccccta tcacatgcat aggatcagtg cgctcgacct ttcaagacaa
    90121 gcaagcatca gctcttgctt gtcttttttt tgcctcaaag cccgttagtc tgctgctatg
    90181 cgaggctttt tttgagtatc agaacctcaa aaaaaaagga catggagtcc tttttttggc
    90241 gatcggtgtt gaggccgtca caaactgccc ttgaaatacg cttctatgtg gagctttttt
    90301 tggtcctgtg acacgtaagc tccaacgacc tccagctgac agcctcttgg aaacaagagc
    90361 tcaacctctg aaggcacagc cgaataaggc tcgacaaagg ctgccttggc cccttttttg
    90421 acacagatgc gcacctccac cggtcgatgg gtcatggcgc cgtttttcaa ggctgtcgtg
    90481 ctcataaaac tgtgcttggt gtagcgtgta ccaagcttga tcttacaaag gatatgaggg
    90541 tcaaactgat ggttacggta gtaagacgtg agatcagcgt gtgaaacacc gatatcacgc
    90601 aaaaacgtct cgtatacata gcggtatact acaatgttcc acgggatgac tagccggtga
    90661 gtcgcagcat cgagctgggc cacctgatcc cttagctcag gcgtgagctg gctgagctca
    90721 cccttggcct tgtctaggct ggtgttgata gggcctgcct gttgacaggt ataagcagcc
    90781 atcgcctctt gctcagccct tgggtagacg agacccttgc cccagcgctt tttaatcagt
    90841 gtctcagcga ccttttgatc cgaaaaggta aaataagcag gcgtcccctc acaaaccgcc
    90901 cgctcatagt gctcacagac aaaaagctcg accaagccct cagtttgcca gatcagacta
    90961 aaacagctaa gaagaaggac aatagccagt tgatagcgct tttttagcat agttccccct
    91021 gaaaccagcc caaaaggctg acccttctcc taggcctttt ggctagctca tgataccacc
    91081 agtttctcag acagactaat ctttttgtca tctctttctc cctaaacaga ctctcttatc
    91141 atgatattat gctattatga gcgatttgtc aatccatagc aaccgttttt tagttagata
    91201 agtaagcttt tgacctagag gcagacaaga gtggcagtac ctcccgtttg ctgtggtggc
    91261 taataaggac taacataaaa tctcaaacgt tttcaaaaac agctcctaag cttaaaaagg
    91321 ctgatgaaca gatttgttga acttaaggga gattgccatg attttctaat catttgatgt
    91381 ttaaaatgat aaaaacatga acttgaaatg aaagaatgcg agtagtaaac tataactaca
    91441 tcaagagtaa tgaaatggag tgattttatg aaaacaaaat caaaacgctt tttaaacctg
    91501 gcaacccttt gcttggccct tttgagcaca accttactaa cgacacagcc cgtgaaagcg
    91561 gaaatagctt tagctgaagg tgagagtact tctcaccaga cagcacaacc aatctctcag
    91621 agcaagttat ttttaggcag tgaaagtgga gaaaatagta cgtatggtca tgatgtttgg
    91681 cgcggactag gacacagtga tggatatgaa aagggaaaag aatcagatag cccagatatc
    91741 ggtgatatcg atgttcctaa ttatgtatca gacaaagaag catataaaga aggttatcaa
    91801 gagggatttg aagagggaag gcgtgaggct agaccaatag agacagtctt agaaactgta
    91861 tggcaattct taacagatat ctttacagat atctttgatg gctggtttgg cagcaacaat
    91921 agctctcagt ctcagtaaat gacacatttg ttgtcttaat gtagttattg taacttattg
    91981 aaaagcttga ggatactttg cttagttcaa gcctttccca cactaatctg ctataattgg
    92041 gataatccct ttagtagtca ggccacctct gataggggtg gcttttttgg gttttagtga
    92101 cccgtgtgtt gagaaaggag catgtatgcc agaaaagaaa gtgttgcccg tccgttgcct
    92161 aatatgaacc gacagttatt ccttattaaa tagacgcaaa tatccacgct ttcactgtgg
    92221 tggctaataa ggactaacac aaaatctcaa acgctttcaa aaacagctcc taagcttaaa
    92281 aaaggctgat gaacagattt gttgagctta agggaggtta ccatgatttt ctaatcattt
    92341 gatgtttaaa atgataaaaa catgaacttg aaataaaaga atgagaggag taaaatagaa
    92401 ccatatcaaa aataatgaaa atggagtgat tttatgaaaa caagatcaaa acgattttta
    92461 aacctagcaa ccctttgctt ggccctacta ggaacaactg tgctaatggg acgtcccgta
    92521 aaggcggagg gaagtgtagt ttcagacaat tcatccggat ccacttcttc gctagtggat
    92581 ggtaatgaaa gagataagat tggtagacaa tatgaatcag gagatctaac attgccttat
    92641 aataaaggga gatatgatgg ttatatagac ggctacgaag atggtaaaaa caaggagccc
    92701 tgcatccgga tcctactggt gatcacttaa ataagttacc taaaactatt ccttataagt
    92761 ttaatgatag aagtcagaaa atgaattatg agggtggcta tagtgatagt tatcctgcag
    92821 gatactataa tggttgggct gataataaca aaattcaagc gactttagaa tggttatggg
    92881 gtgaaataag caattggttt tctagtatat ttacaactga ctagtctatc atcttactaa
    92941 agcgattttc attttttata ctaacttaac tatagtagtt agttcaaaaa agctgattaa
    93001 cagcctaaaa caaactcttt ctctgacaag aaaaagcgtt atgctttccg aaccattttg
    93061 tcttttaaat aataaaaaat gagcttgaaa tgaacttgaa atgaaacagt gagaggtaag
    93121 agatataaaa taagatcgtc gaaaataaaa aaacggagta atttttatga gaacaaaatc
    93181 caactacttt ttaaacttag caactctttg cctagctctt tttggagcaa ttttactaat
    93241 ggcacaacca gcaaatgctg aggaagtatc tccaaacatt ggagttgagg gtacttctac
    93301 tagacagtat tatggtgaaa tgcaggaaga atatgatgag gaagcagagc tctcttcaaa
    93361 agatagagaa ttcgggagac aaaatggtca aaaagatggc aaagagggta aaaatggatt
    93421 tggcccaaca ataaatcgaa atgatataca agttcctgaa aaagtaaaac atcaagatga
    93481 atatcaggat gggtatgaac aaggttatcg tgagggatgg cagcaggagc atccacttct
    93541 aggagttgta ttcgatgttt ttgatttgat ctggggtgca gtaggtggtt ttttcagttt
    93601 agctaattag ttatagttac gctattagag agtaatatta tctgttgaaa gtactgtaat
    93661 gtttaggcta cagcgctatt tttggtacat atagctaaaa gtactacagt taatttttta
    93721 tcacaagcca ttcccacaca aatctgctat aattgggata gtccctttag tagtcaggcc
    93781 acctctgata ggggtggctt tttttggggt tttagtgacc tgtgtgttga gaaaggagca
    93841 tgtatgccag aaaagaaagt gttgcccgtc ctaagcatga tgatgagttt tgtctgtctg
    93901 cttgatcata tcttcttttt tgctacttat agttatctct acttgccgct tgtagcaagc
    93961 agtctagctc ttatcggtct ggtgcaaaac aaaggcaggc aaaaggtttg gtcgctagtt
    94021 gggcttatcc tagctgctct agccgtggca gtagtgacct atgcctacta tgacccaacc
    94081 gtcatcccct attaacctta ccccctcttt gcatgcaatc agcagcacaa aaagcacccc
    94141 tgacaggtgc tttttgtgct ttagccaacc tcatagcctc ataaaccctc actgaaacag
    94201 tcccttaaag ttccaccact gatcttggat gctttcgctt aaccgctgat gccaaggttt
    94261 atttgatcta tcattcgcag catttttaaa taagtctaga gcttcacgtt cttgttcttg
    94321 gagttcaagt tcttctagga tttctgctat ttctttttcg tacttttctt cttctttttc
    94381 aatttggtct ttgggtttag atttgccaat gatccacgtc tcagatccta ttccaaatcc
    94441 ctcagagtct tttattgtaa ttctaacttt atccccatat acagtagtta ctttcggggg
    94501 atttctgttc tctttttttt gtaaattaag cttggctttg ccactagagt cagccctacc
    94561 aaatactgct ggctcactat ttaaagaagc aataataata gcatgaggct cagtttttac
    94621 ttcaacttct gagtctccta tattaatagg ttttatacca aatgattgtg actcacacca
    94681 atcggttctg aacccaattt ttttgggatc acccgtggaa agaggtggca tcgtataatc
    94741 gtcgtcacca tagtatccct tacctaaatt ggagttacta tcatagcgac tatccgctct
    94801 gacgctacta gttaccccga tggcaaagag tgccagtagc aaggttaatg tctttttcat
    94861 tttttcctct ccttttgctc attttttaag acaaggctta ttataccaat tcttgcgcta
    94921 aaaagatagg gagttcatgt cttgtggttg ggaaatggcg cgactattct tggtaggggc
    94981 agacaggttt tttcctagcc agttgctagc cgttgccatt ttacctttgc aagccgtttg
    95041 ggcatcaggt cgtgttttga ggttgccaat acttttagtt gctttttgac aaaaatgcgt
    95101 tatgatagac taaataaaag aagatagcat tttcgatgaa tgatgcgtga gtccacaaat
    95161 ttatttttag gagtttatag actgcctaaa gtgtctattt cgtcaataaa ggagaacaat
    95221 atgacatttg aagagatttt accaggttta aaagccaaga aaaaatatgt acgtacaggt
    95281 tggggtggcg ctgaaaatta tgtgcagttg tttgataccc ttgaagtgga tgggaaagta
    95341 ctacaggcga cgccttattt tctgattcat gttactggtg caggtgaagg tttttccatg
    95401 tgggcgccga caccatgtga tgtgttagca gaggattgga tcgaggtcaa tgactaaagt
    95461 tgttttagtg acgggctgtg ctagtggaat tggttatgca caggcccgct attttttgag
    95521 acaagggcat cacgtatatg gtgtggataa gtcggataaa ccggacttaa acggtaactt
    95581 tcactttatc aaattggatt tatcctctga gttatcccca ctatttaaag tggtccccag
    95641 tgttgatatt ttgtgtaata ctgcagggat tttagatgcc tacaagccac ttttagacgt
    95701 cagtgatgaa gaagtggaac acctatttga tattaatttt tttgcgacgg tgaagttaac
    95761 acgtcattat cttagacgta tggtggaaaa gcagtcaggt gttattatca atatgtgttc
    95821 aatagcaagt tttatagcgg gtggcggtgg tgttgcctat acgagttcta agcatgcgct
    95881 tgcgggcttc acgcgccaat tggctttgga ttacgccaaa gatcagattc acatttttgg
    95941 tatagcgcca ggtgctgtca aaaccgctat gacggctagc gactttgagc ctggtggctt
    96001 agcagactgg gtagctcgtg agacgccaat tggtcgttgg actaaaccag atgaagttgc
    96061 tgaattaacg ggatttcttg cgtcaggaaa agcgagatca atgcaaggtg aaattgtcaa
    96121 aattgatggt ggctggactt tgaaatgatc acatgcctta gcttgagctg gcgcagtaag
    96181 ccctagaggt gtgatgagtc aaacagtcaa aggagatgaa caaatgaaat tagcggtttt
    96241 ggggacaggt atgattgtta aggaagtttt gcctgtcttg cagaaaattg atggtattga
    96301 tttagttgct atcttatcaa cagttagaag tttaacgaca gctaaagacc tcgctaaggc
    96361 atatcacatg cctctagtta cgagtaaata tgaggctgtc ttaggcaatg aggagattga
    96421 tacagtttat attggactgc caaatcacct gcattttgcc tatgctaaga aggctcttct
    96481 agctggtaaa catgtcattt gtgaaaagcc ctttaccatg acagcaggag aattagatga
    96541 actggtggta atcgctaaaa aacgaaaact cattttgtta gaagcgatta cgaatcagta
    96601 tttaagcaac atgaccttta tcaaagagca ccttgaccaa cttggcgata tcaaaattgt
    96661 agaatgtaac tattcacaat attcttcacg ctacgatgcc ttcaaacgag gtgatatcgc
    96721 gccagctttt aatcctaaaa tgggtggtgg agctttacgt gatttaaaca tctacaacat
    96781 tcattttgtg gtagggttat ttggtcgccc taaaacggtt caatatttag ccaatatgga
    96841 caagggcatt gacacctcag gcatgcttgt catggactat gagcagttta aagtggtgtg
    96901 tatcggggcc aaagactgca ctgcagaaat caaatcaacc atccaaggta ataaagggtc
    96961 actggcagtg cttggagcaa caaataccct tcctcaagtt cagttaagtc tacacggtca
    97021 cgaagcacaa gtgattaacc acaacaagca tgaccaccgg atgtatgagg agtttgtcgc
    97081 ttttagggac atgattgacc aaaaagacta tgacaaggcc aatctagctt tggagcatag
    97141 ccgagctgtt atggctgtgt tggagcgagc tgttcattcg tgatggtaat ctggtagcta
    97201 ttgccttttg tgcagttgct atggtaatgg ttgaaagacg tgttttcacg agggttaatc
    97261 ccctcgtgct tttttggcaa aaataacttg ttcaggattt gggttttctt tgtgagatga
    97321 gagatgcctg acgaattgat ttgattaaaa taatgataaa gccaaacgat ttaagaaatg
    97381 accgttcgga aattctgccc caaaggggct ctagaagcag taaaatcgaa tttgtaagcg
    97441 ttgacactgt tgcataactc tgttacacta agagaatgtc atgacaaaaa ttacagtgta
    97501 ggagtttaat tgtttatgga agaggattat aacaaaagag aacctgagaa gtttacgcaa
    97561 tttctgcgcc gtcaaaaggt tgtctttttt gtcgcatttt ttggttatgt gtgtgcctac
    97621 ttggtacgca acaatttcaa actaatgtca aacactatta tggtacaaaa tggttgggac
    97681 aaggctcaaa ttgcgacctt gttatcgtgt ttgaccgttt cttatggttt agcaaaattc
    97741 tatatggggg ccttaggaga ccgtgttagc ttgaggaagc tcttttcaat cagcttgggt
    97801 gcaagcgctt tgatttgtat tttaattggt tttttcaata gttcaatggt ggtgttaggg
    97861 atactgctag tcttgtgtgg tgtcgtacaa ggtgccttgg cacctgcctc acaagccatg
    97921 attgccaatt attttccaaa taaaacacgc ggcggagcca tcgctggatg gaacatttct
    97981 caaaacatgg gatcagccct cttgccatta accatcgcct tgctcaccag tatgggcttg
    98041 gtggtaccag ctaatggtaa tattttactt gcctttttaa tccctggcgt tttagtgttc
    98101 ttgtttgctt tgtgttgctg gaagcttggt ggtgataacc ctgagtctga gggacttgac
    98161 tctcttcgaa cgatgtatgg tgatgcgggc gagtcagctg ttgccagtga agaagaaaag
    98221 cataacctgt cttattggca actcatctgg aaatacgttt tttgtaaccc gtcgctctta
    98281 cttgttgctg ctgtcaatgt ggccctttat ttcgttcgtt ttgggattga agactggatg
    98341 ccgatctact tgtcacaagt agccaatatg tcagaggctc atattcattt tgcgatttca
    98401 atgttagagt gggtagctat tccaggctcg ctggtatttg cgtggttagc ggttcgttat
    98461 cctaataaaa tggccaagat tggggctatt gggctttttg tgttagcggc tattgtcttt
    98521 gtctatgaac gcttgactgc cgcaggtgct ccaaactatt tcttgttgct tgttatttca
    98581 ggtattttag gggcattgat ttatggccca cagttgatcg tgaatatttt aacaatcaac
    98641 tttgttcctt taaatgttgc aggaacagcg attggttttg taggagtaac agcttatctc
    98701 atcggcaata tgggagcaaa ctggttgatg ccgattttgg cagatggttt tggctggttt
    98761 tggtcatata ttgtcgttgc agccttatct gctttttcag cggttggtta tttaatttta
    98821 gccaaacgtg aggaagaaat catcaaagat tagctaggca aatgcctaag aaagacagac
    98881 ttattgctga agtcctgtct tttttagtca tcacaagccg caaatgacac tataaaagac
    98941 aagaaaatgc taggatgttt caggaaaaaa agagaaaata tgctataatg agaaggtatt
    99001 taaattatat agtaaggaaa aacaaatgac aaattatgcc attattttag cagcgggcaa
    99061 agggactcgc atgacttctg atctcccaaa agttcttcat aaagtatctg gactaaccat
    99121 gcttgagcat gtttttcgta gtgtaaaagc gattagtcct gaaaaatccg tgacggttat
    99181 tggtcacaaa tcagaaaagg tacgtgctgt cttagcagat caatcagcct ttgtccatca
    99241 aacagagcag ttaggaactg gccatgccgt gatgatggca gaaacacaac tagaaggact
    99301 agaagggcat accttggtga ttgcaggaga tactcccttg atcactggag aaagcctgga
    99361 gagtctgatt gattttcatg tgaatcataa aaatgtcgcc actattttaa cagctacggc
    99421 tcaagatcca tttggttatg gtcgtattgt tcgcaacaaa gatggcgaag tgatcaagat
    99481 tgttgagcaa aaagacgcca atgagtatga gcaacaatta aaagaaatca atacaggaac
    99541 ctatgtgttt gataacaagc gtctctttga agcgctcaaa tgcatcacta ccaacaatgc
    99601 tcaaggagag tattacctga ctgatgttgt ggctattttt agagcaaaca aagaaaaggt
    99661 aggagcctat atcctgagag acttcaatga aagtcttggt gttaatgatc gtgtagcctt
    99721 agcaacagct gaaatagtga tgcgccagcg cattacccaa aaacatatgg tcaatggggt
    99781 gactttccaa aatcctgaaa ccgtttatat tgaaagcgat gttgagattg caccggatgt
    99841 tttaattgaa ggaaatgtga ccttaaaagg acgtacacat atcggctcag gaactgtctt
    99901 gacgaatggt acttatattg tggattctga aattggtcaa ggaagtatca tcaccaactc
    99961 aatgatcgaa tcatctgttc tagctgcagg agttacggtt ggcccttacg cccaccttcg
   100021 tccaggaacg accttagata gggaagtcca tatcggtaac tttgtcgagg tcaagggttc
   100081 tcacattggt gaaaaaacaa aggctgggca tctgacttat attggaaacg ctcaggttgg
   100141 gtcttcggtc aatgttgggg ctggaaccat cactgtcaac tacgacggcc aaaacaaata
   100201 tgaaacagtc attggagatc acgcttttat tgggagcaac tcgactctca ttgcaccttt
   100261 ggaagttgga gataacgctt taactgcagc tggctcaact atttctaaga cagtaccagc
   100321 tgatagcatt gttattggtc gtagccgcca agtcacaaaa gaaggttatg ccaagcgcct
   100381 agcgcatcac ccaagtcgaa gcaaataatt caagatctat ttagtaagga ggccaggcat
   100441 gaaatttgaa gaaaaaacgc ttaagagaca aacagttttt gatggtcata tttttaaagt
   100501 tgttgtggat gatgttgaac ttcccaacaa tctggggcaa tccaagcgag aattaatttt
   100561 tcatcgtggc gccgttgctg ttttggctat tactcctgaa cgtaagattg tccttgtcaa
   100621 acaataccgt aaggctattg aaagtgtctc atacgagatc ccagcgggta agctagagat
   100681 tggtgaggaa ggctcaaagc taaaagctgc tgcacgtgag ctagaagaag aaacagccta
   100741 tacggggaca ttgacgtttt tgtatgaatt ttatacagcg attggttttt gcaacgaaaa
   100801 aatcacactt ttcttagcga cagacctaac acaagttgcc aatcccaaac ctcaagacga
   100861 cgatgaagtt atcgaggtct tagagttgac atatcaagag tgcatggact tagtcgctca
   100921 aggtaaactt gctgacgcta aaacgttgat tgctttgcaa tactatgcct tacattttgg
   100981 aggtgagcag tgatgggaag gccattgttg accgatgata tcatcgaaaa agcgagacga
   101041 atggaaacat ttgagccaga tgatgctgta gactttgaca caaaagtaat gacgctacca
   101101 gaaaaagatg ataaagcacg catttataaa agccgtcgga ttgaaaatgc caaacgcagc
   101161 caattgcaat ctaaattaaa tgtgattttg atagctgtta tgctgttaat tgccatcttg
   101221 gtatatgcta tcttttatct ttaaaaaaac gtaaggaaat gatatgaaaa taggaattat
   101281 tgctgctatg gaggaggagt tgtccctgct cttagcaaac ctcttggatg ctcaagaaca
   101341 tcaggtgctt tcaaaaactt actatacggg tcgttttggc aagcatgagc tcattttggt
   101401 acagtcaggt gttggaaaag tgatgtctgc tatgacagtt gcgatcttgg ttgagcattt
   101461 caaagcccaa gctattatca atacaggatc agcaggggca gtcgcttcac atttagcgat
   101521 cggagatgtg gtggttgcag atcggttagt gtatcatgat gtggatgcta ctgcatttgg
   101581 ttatgcttat ggtcaaatgg ctggtcaacc attatactat gattgtgatc cacagtttgt
   101641 ggctatcttc aaacaagtcc taaaacacga aaagacaaat ggccaagttg gtttgattgc
   101701 aacaggagac agttttgttg ctggtcagga caagattgac cagatcaaaa cagcttttag
   101761 cgacgtgtta gcagtagaaa tggaaggcgc agctattgct caagcagcac atactgcagg
   101821 taaacctttc atcgttgttc gtgcgatgag tgataccgca gcgcatgatg ccaatattac
   101881 ttttgatcaa tttattatag aagctggcaa gcgttcggcc cagacattaa tgacattttt
   101941 agaaaactta cctgtttaac tcactttatc gtgagacaat tagctggata atctctattt
   102001 taggagtctg gtcacctctt gttttgaaac ctaaaaataa gaattgcaat cacttgacca
   102061 aacgctataa tgggttaagg aacgatagat tactaaaagg agtctaaaaa tgacactaaa
   102121 aaaacactat tatcttctca gtctgctagc tcttgtaacg gttggtgctg cctttaacac
   102181 aagccagagt gtcagtgcac aagtttatag caatggagga tatcaccagc atttgactga
   102241 tcaaaaatca cacctgcaat atagtaaaga caacgcacaa cttcaattga gaaatatcct
   102301 taacggctac caaagtgacc tagggaaaca ctactctagc tattattact acaacctaag
   102361 aaccgttatg ggactatcaa gtaagcaaaa gattgaagaa cactatgaaa agcttaaaga
   102421 tgagctatac cgcatgtaca atcattatta agttaaaggc ttaaaaatgg agactagccc
   102481 ctcaaaaaaa gaggccacac tcatttaaat ttaaatgagt gtggcctctt tttgaggaga
   102541 cgcaaggggt taaagggctg tgacatagag ttgcttagca atattttcag ggatgataag
   102601 gtccttgtcg tcataacaaa tcgtataggt ttttgcaaag gtatcaattt gagttaaggt
   102661 tagctcggta ttgatattga ggtgatgtgc ttctagatac tggattaaat caaagtggtc
   102721 gtggattctg cttagacgaa accgtcccaa ctccgtgatg gtgttgagag ttgtagtgtt
   102781 catttcgaca agaggctgac catagcgagg aatagtccct ccgtgtgggc agaaatctgg
   102841 aaaatcaagg accttgtcta aacggtcgat aaaggtgtct gagacagtgt gctctaagac
   102901 ttcagcttct tggtgcactt cttgggtatt atagcccagc tggtgaatca aaaatacctc
   102961 aatcaagcgg tgtttgcggt agaggttagc aacaagagca tagcctttgt cttttagcaa
   103021 atagcctttt gctttatctt tgacaatcca gccttgtgaa atcatttttt taatcatctc
   103081 tgaaacggca ggtgccgaaa cgtgcatctt ttctgcaacc attttatttg taatcttggt
   103141 ttcttgttct ccaatttcat agatacattt caagtaatct tctttattag gcgtcatatc
   103201 gtttggcctt tctcttattt ataatgatta ttatatcaga atttttagga aaaagcttga
   103261 caaaaagcct aaaagaggat atccttatag cataattaac taaacttaat taaataaata
   103321 atatatccta aggagagaaa tgatgggaaa gagaatgagc ctcattttgg gtgctttttt
   103381 atctgttttt cttttagtag cttgttcgtc aactggtact aaaactgcta agagtgataa
   103441 attaaaagtc gtggcaacca attcaattat tgccgacatg acaaaagcta ttgctggtga
   103501 taaaatcgat ctgcacagca ttgtgccaat cggtcaagac cctcatgagt acgaaccatt
   103561 accagaagat gttgaaaaaa caagtaatgc tgatgtgatt ttctataatg gtatcaatct
   103621 agaagatggc gggcaagctt ggttcaccaa actagtgaaa aatgctcaaa aaacgaaaaa
   103681 caaagattac tttgccgtgt ctgatggcat tgatgtgatt tacttggaag gtgcaagcga
   103741 aaaaggaaaa gaagatccac atgcttggtt aaatctcgaa aacggaatta tttattcaaa
   103801 aaacattgcc aaacaattga ttgcaaagga tcctaaaaac aaagaaactt atgaaaagaa
   103861 cctaaaagct tatgtggcta aattggaaaa actagacaaa gaagccaaat caaaatttga
   103921 tgctattgca gaaaataaaa aattgattgt gactagtgaa ggctgcttca agtacttttc
   103981 aaaagcttac ggtgtcccat ctgcttatat ctgggaaatt aacaccgaag aagaaggaac
   104041 accagatcaa atttcatcat tgattgaaaa actaaaagtc atcaagccat ctgcgctttt
   104101 tgtagagtca agtgtcgata gacgccctat ggaaactgtt tctaaagata gtggtattcc
   104161 tatttattct gagatcttta cagattcaat tgctaaaaaa ggtaaacctg gcgatagtta
   104221 ttatgctatg atgaaatgga accttgacaa aatttctgaa ggtctagcaa aataagataa
   104281 caataaagca cagcgatttt agtgttgtgc tttgttttat ttatgtaaag gagacaaaat
   104341 gattacaact aacaatcttt gtgtgaccta cgatggcaac agtaatgctt tagaagcgat
   104401 taatgtgaca attgaaggtc cttctatcgt tggtattatc ggtcctaatg gagctgggaa
   104461 atcaaccttt atgaaagcta ttttaaatct tattgattat caaggtcacg taacggttga
   104521 tggcaaagat ggtcgtaagc ttgggcatac agtagcttac gtagaacaac gaagcatgat
   104581 tgactataat tttcctatta ctgttaaaga atgtgtggcg ctagggactt atagtaaatt
   104641 aggccttttt cgccgagtag gaaaaaaaca atttgagcag gttgataagg ttctcaaaca
   104701 agttggttta gaagactttg gccatcgacc gataaaatcc ttatctggtg gtcagtttca
   104761 gcggatgttg gttgcgcgtt gcttgattca agaatcagac tatattttct tagatgaacc
   104821 gtttgttggc attgactcgg tcagcgaaaa aatcattgta gatcttttga aagagctcaa
   104881 aatggctggc aaaacgattt taattgtaca tcatgatttg agcaaagtag agcattattt
   104941 tgacaaactc atgattttaa ataaacattt ggtggcttat ggtaaggtta atgatatttt
   105001 tacagttgat accttgtcaa aagcttatgg caatcatttg attttaggaa aggagatggt
   105061 gtaaatgtct atgaaatttt ttgagggctt gatgtcatac cactttttac aaaatgcact
   105121 gataacggct gtagtcattg gtatcgtctc aggtgctgta gggtgtttta ttatccttag
   105181 gtcaatgtct cttatgggtg atgccatctc acacgctgtt ttaccagggg ttgctttgtc
   105241 atttatttta ggagtcaatt tttttattgg agcgattatt tttgggctat tagcttctgt
   105301 tattattact tatatcaagg aaaactctgt cattaaagga gatacggcta ttggtatcac
   105361 ctttagctct tttttggcac tgggagtcat cttgataggg gtagccaata gttcgacgga
   105421 cttatttcat attttgtttg ggaatatttt agctgtgcaa gacagcgata agtggattac
   105481 tattggtgtt tcgatttttg ttttaggggt tattagtctc tttttcaaag aactattatt
   105541 aacatcattt gatcctatct tagccaaatc aatgggtgtg aaggtcaatg cgtatcatta
   105601 tttgttgatg gtcctattaa ctttagtggc tgttacggcg atgcaaagcg tgggtactat
   105661 cttgattgtt gccttactga ttacgccagc agcgacagct tatttatatg ctaatagctt
   105721 aaaagtaatg ttagtgatgt catctttact aggcgcttta gcatcggttt tagggcttta
   105781 tttgggttat acctttaatg ttgccgcagg gtcaagtatc gtactgactt ctgcgatgat
   105841 gtttttgatc agtttctttg tttcacccaa gcaaggctac ctcaaaagat ggatgcaaaa
   105901 aaaagaaaaa acaccttaaa cttttcattt taaacacctt agtggtttgc aaatagtagc
   105961 aaatgacatc aaagggtgtt ttttatatgt catcaaaaga ccataaaaaa ccttatcaaa
   106021 ccaaggtatt tagcctatta tctgataagg ttttttaagc atgatttagt ttttaaagcg
   106081 ataatctttg acaatgtcaa ttgaggtaat cgtaatgtct tgttctggtt tatcattttg
   106141 gttgatagaa gtcgcggcaa ttttatcgac aacatccata ccatcaatga cttgaccaaa
   106201 tacagtataa ccgccatcta agcttggatt accgccatgc tcataggcag agatgatagg
   106261 ttttgggtag ttggtacttg ataatccctt gctttgattt ttcttgtttt ggttgatata
   106321 aaattggcta ccgttcgtat tagcgccagc atttgccatg gcaagagcac cgcgaatatg
   106381 atataaaaat ggagagattt cgttgacaaa gccattgcca gcatcttttt taggatcctt
   106441 gcccttccaa atcgattcac cacctgtgcc atctcctttg gggtcacctg attgaatcat
   106501 aaagtcgttg atcacacgat ggaaagtaag gttatcatag tagccttttt tagcatgggt
   106561 gaggaagttc tcaacagcta agggagcata ttttgggaat aacttaaggg taatgtcccc
   106621 ttgacttgtc ctcattacga ccttagcttc ttctttgccg acttctttgg ttagttgtgg
   106681 aaattggcta gcatcagctt tgagagcttt ttgaatgctt tcttcatagg ctttagaagc
   106741 tgcttcgctt tcttctttgg cagttttttc atcaatgtat ttatcgcctt ttatagcgcg
   106801 gtcaacagat tcacaagcac tcaaactaag taaactaatg gctactaaac tgagagataa
   106861 taattttttc atgtctactc ctaagaatga ttttctttat tttatcataa aatgcaacag
   106921 aaaatagtag taaagagtta aaaacgccta tttttgtgtt ttatgatcta accttggtta
   106981 aaaggctgct acgactgtta ttatagcaca agatgctata gaaaaactta aaacaccttg
   107041 gttttttaga gctatttcct aatagttaaa aaatggtata atagtgttat ggttaaaaga
   107101 aatcaaagaa gaaaaagtgc gcctaagaag cgtctgacaa aagcagaagt ggaaaagcaa
   107161 cgtgccatta agaggatgat tttatctgtt ttaatggctt tgttgcttat ttttgcgatg
   107221 cttcgcttgg gcgtctttgg cgtgacaact tataatatga ttcgtttttt ggtgggtagt
   107281 ttagcctatc cgtttatgtt tgcctggtta atttacttat tttgttttaa atggttacgg
   107341 caaaaagatg gaatgattgc gggagttgtt attgcctttt tgggattgct agttgagtgg
   107401 catgccttct tatttgcgat gcctaggatg cttgatcaag atatttttct aggcactgct
   107461 cgactaatta caagagattt actagccctg cgcgtgactg aatttgttgg tggaggaatg
   107521 cttggtgcat tactttataa acccatagcc tttttatttt cgaatatcgg ctcttacttt
   107581 attggttttt tgtttatctt attaggatta tttctaatga cgccttggga tatctatgat
   107641 gtgagtcact ttgtgaaaga ggctgttgat aaactagcag tggcttatca ggaaaataaa
   107701 gaaaagcggt tcatcaaacg agaagagcac cgcttacaag ctgaaaaaga ggctttagag
   107761 aaacaagcac aagaggaaga aaaacgtcta gcagaattga cggttgatcc tgagacggga
   107821 gagattgttg aggatagtca gtctcaagtc agctatgatt tggctgagga tatgacaaaa
   107881 gagccagaga ttcttgctta tgatagtcac ctcaaagacg atgagacaag cttatttgat
   107941 caagaagact tggcttatgc tcatgaggaa attggggctt atgactcttt atctgcttta
   108001 gcatcttctg aagatgagat ggatatggat gaacctgttg aagttgattt cacgccaaaa
   108061 acccatcttg tttataaact tccaacgatt gatttatttg caccagataa gcccaaaaac
   108121 cagtccaaag agaaaaactt agtccgcaaa aatatcaagg tgcttgaaga taccttccaa
   108181 agttttggga ttgatgtcaa ggtagagcga gcagaaatcg ggccttccgt caccaaatat
   108241 gaaatcaagc cagctgtcgg ggtccgagtt aatcgtattt caaatcttgc tgatgatttg
   108301 gcacttgctc tggctgctaa agatgttcgt attgaagcac caattcctgg aaaatcctta
   108361 ataggtattg aagttcctaa ctcagaaatt gcaacggttt ctttccgcga actttgggaa
   108421 caatctgatg ccaatcctga aaatctttta gaagtaccac taggtaaagc tgttaatggc
   108481 aacgctcgca gttttaactt agctagaatg ccgcatcttt tggtagctgg ttcaactggt
   108541 tcaggtaaat ctgtggcagt taatggcatt atttcaagta ttttgatgaa ggcacgtcca
   108601 gatcaagtta agtttatgat gattgacccc aaaatggttg aattatctgt ttataatgat
   108661 attccacatt tattaatccc agttgtaacc aatccgcgta aagccagtaa ggcactccaa
   108721 aaagtggttg atgagatgga aaaccgctat gagttattta gtaaaattgg tgtgcgtaat
   108781 atagcaggtt ataatacaaa ggttgaagag tttaatgctt cctctgagca aaaacaaata
   108841 ccgttgcctt taatcgttgt cattgtagat gaattggctg acttgatgat ggtggctagt
   108901 aaagaagttg aagatgctat tattcgtttg gggcaaaaag cacgtgctgc aggtatccat
   108961 atgattcttg caactcaacg tccctctgta gatgttattt ctggtttgat taaagcaaat
   109021 gttccgtcgc gtatggcatt tgctgtttca agtggtactg atagccgtac gatccttgat
   109081 gaaaatggtg ctgaaaagct cttgggacgg ggtgatatgc tctttaagcc gattgatgaa
   109141 aatcaccctg ttcgcttgca agggtctttc atctcagatg atgatgtgga gcgtattgtc
   109201 aactttatca aagaccaagc tgaagcggat tatgatgacg cctttgatcc tggtgaagtt
   109261 agcgacaatg atcctggttt ttctggaaat ggcggagctg ctgaaggtga tcctcttttt
   109321 gaagaagcaa aagccttggt cttagaaaca caaaaagcta gtgcctcaat gattcaaagg
   109381 cgtttgtcgg ttggatttaa tcgtgccacg cgcttgatgg atgaattgga agaagcaggt
   109441 gttatcggtc cagcagaagg aaccaaacct cgtaaggtat tacagacaaa ctaaaagaac
   109501 ctgacgtctc atgatgagat gttaggttct ttttttgtga tgtcaagcca gttgatgaga
   109561 tgcctatgct aatgtaaaaa taaagataac tagaatcagg tagaaaataa cggtgactaa
   109621 aaagccaact cgccaaaata gcttcataaa gcgatggtaa gaaaacgact gagttcggat
   109681 gactagcagt agtgaaatga cgatggctag cagcgacatg ataataaggt aataaggcag
   109741 taaattatgg gtgaaaaatt ttcctgagac aagcacaatt tctatcgcaa aaagtaaaag
   109801 tgcgacatct ggaaatttaa atcccttttt attaagttta aataaagagg ttacaatcat
   109861 ggcaaaaaga ggcgttacta tcaagaaagc taaggcagtt aatttataga tcatcatagg
   109921 tctattttat actcaaatcc cttacttgta aactgatact tacctgttgt gatagaaaat
   109981 gatctttgag agggaaagcg cctacttcaa tttaaacatt gcaaaaggca tcagctattt
   110041 taacaaaaag acttgattta ttttggcaat aagctataat agtaaggtat gcaatattgc
   110101 atatctgtgg gaggtaaaaa tctcaattac cgccaaaacc acaacaggag gatttttaaa
   110161 atggctaaaa aagtcgaaaa acttgtaaaa cttcaaatcc ctgctggtaa agctacacca
   110221 gctccaccag ttggaccagc tcttggtcaa gcaggtatca acatcatggg cttcactaaa
   110281 gaatttaacg ctcgtacagc tgatcaagct ggtatgatca tcccagttgt tatctcagtt
   110341 tatgaagaca aatcatttga tttcatcact aaaacaccac cagctgctgt tcttttgaaa
   110401 aaagctgcag gtgttgaaaa aggatcaggt acacctaaca ctactaaggt tgcgacagtt
   110461 actcgtgcac aagtacaaga aattgctgaa actaagatgc cagatttgaa cgctgcaaac
   110521 attgaagctg caatgcgtat gatcgaaggt actgctcgtt ctatgggatt cactgttact
   110581 gactagtcag tcaagaaccc ctattacccg cacgacttca tcataagaga tgagtgacgt
   110641 gggagatttt aaatcaaatc gatatgacca cattacaagg agaattttaa aatggctaaa
   110701 aaaagcaaac aaatgcgtgc tgcacttgaa aaagtagata gcacaaaagc gtacagtgta
   110761 gaagaagctg tagcattagt aaaagaaacg aacttcgcaa aatttgatgc gtctgttgaa
   110821 gttgcttaca acttgaacat cgacgttcgt aaagcagacc aacaaatccg tggcgcaatg
   110881 gtattgccaa acggaactgg taaaacacaa cgtgttcttg tttttgcacg tggtgcaaaa
   110941 gctgaagaag caaaagcagc tggtgcagac ttcgtaggtg aagatgacct tgttgcaaaa
   111001 atcaatggtg gatggcttga ctttgacgtt gttatcgcaa cgccagatat gatggctatc
   111061 gtaggtcgcc ttggacgtgt ccttggacct cgtaacttga tgccaaaccc taagactggt
   111121 acagtaacga tggatgttgc taaagccgtt gaagagtcta aaggtggtaa aatcacttac
   111181 cgtgctgaca aagcaggtaa tgttcaagct cttattggta aagtttcatt tgatgctgac
   111241 aaattggttg aaaacttcaa agccttccac gatgtaatgg ctaaagctaa acctgcaaca
   111301 gctaaaggaa cttacatggc aaacgtctca atcacatcaa cacaaggtgt tggtatcaag
   111361 gttgatccta actcacttta agaaaaaaat tagggcatcg cctaatcata gcaaaaagac
   111421 aaatttctga agacaaatct tcactagagg tttgtctttt ttatggttta aaatggaatg
   111481 caaacaaaaa agtgtaggcg ataataccat gaaaggagtt gattctctta atgagatgtg
   111541 gtgttaacac atcatgagct cacaaaaaat gataaagaaa gtatcagtgg tgttaaaaaa
   111601 gggattttaa ttgatattta ttagcctcta aaatgtcctt tccctattca taattgaggg
   111661 tttgtggtaa aatagtaagg acaaactaag gagaacatag tagtggaacc taaatatcaa
   111721 cgtatattaa ttaagttatc tggtgaagca ttagcaggtg aaaaaggagt tggcattgac
   111781 attccaactg ttcaggctat tgcaaaagaa attgccgaag ttcatgtgtc gggagtacag
   111841 atcgctcttg ttattggtgg aggcaatctc tggcgtggag agcctgcagc agacgctgga
   111901 atggaccgtg ttcaggctga ttacactggc atgcttggaa cggtgatgaa tgccctagtc
   111961 atggctgata gtcttcaaca ttatggtgtt gatacccgtg tgcaaacagc tattcctatg
   112021 caaaatgtag cagaacctta tattcgcgga cgtgccttgc gccatctaga aaaaaatcgg
   112081 attgttgttt ttggagctgg tattggctcg ccttattttt caacagacac caccgcggca
   112141 ctgcgtgctg ctgagattga agcagatgct attttaatgg caaaaaatgg tgtggatggg
   112201 gtctataatg ctgatcctaa aaaagatgct aatgcggtta aatttgatga attaacacat
   112261 ggtgaagtga tcaaacgtgg tctcaaaatc atggatgcaa cggcatcgac cttatcgatg
   112321 gacaacgata ttgatttggt ggttttcaat atgaatgaag ctggcaatat tcaacgtgtt
   112381 gtctttggag aacatattgg aactactgta tcaaataaag tttgtgacta aaagttagaa
   112441 aagaaagaga gtaattatca tggcaaatgc aattattgaa actgcaaaag aacgttttgc
   112501 acaatcccat cattctttat cacgtgaata tgccagcatt cgtgcgggtc gtgccaacgc
   112561 tagtctttta gaccgtatcc aagttgatta ttacggggca ccgacgccat taaatcaatt
   112621 ggcttcaatc actgtgccag aagcgcgtgt cttattgatc tcgccttttg ataaatcttc
   112681 tatcaaagat atcgagcgcg ctcttaacgc atcagattta ggcattacac ctgctaacga
   112741 tggctctgtc attcgtttgg ttattccagc tttgaccgaa gaaacacgta aagaattagc
   112801 caaagaagtg aaaaaagttg gtgaaaatgc taaaattgca atccgtaata tccgccgcga
   112861 tgctatggat gatgctaaaa agcaagaaaa agcaaaagaa atcactgaag atgagttaaa
   112921 aacacttgag aaagatatcc aaaaagcaac cgatgatgct atcaaagaaa ttgaccgcat
   112981 gacggctgaa aaagaaaaag aattgctctc agtgtaacag gatttctacg aaaaatagac
   113041 gactatagac acaaaaagat aggtgaccat ttcagaagcg tttggttttg atttgtccct
   113101 atttttttaa agaaagaaaa aagatatgaa tgatttacta gcaacagtca ttactgggct
   113161 tattaaagaa gaaaacgcta atgactattt tatccaaaaa gaagggttta cctttacctt
   113221 gtctaaagca gaaggagaac gccagattgg tgatatggtc acaggctttg cctatataga
   113281 cataaagcaa aaggcacgtc tcacaaccaa agagatccgt tcaacacgga caagttatgg
   113341 ctggggggaa gtgacagagg ttcgtcgtga cctaggcgtt tttgtcgata caggaattcc
   113401 aaataaagaa attgtggttt ctttggacgt gttgcctgag atgaaagaat tgtggcctaa
   113461 aaaaggggat aaactttaca ttcgtttgga tgtggacaaa aaagaccgta tttggggact
   113521 tccagcagag tctgaggtct ttcaaaagat ggctagccct gcatacaata acatgcaaaa
   113581 tcaacattgg ccagcaattg tttaccgcct aaaactaaca ggaacgtttg tttacctgcc
   113641 tgaaaacaac atgttgggct ttattcaccc aagtgaacgc tacgcagaac cgcgcttagg
   113701 tcaggtttta gatgcccgtg tgattggctt tagagaggtc gatcgtaccc taaacttgtc
   113761 gttgaaacca cgttcttttg agatgttgga gaatgacgct cagatgattg ttacttatct
   113821 ggaagccaat ggtggtttca tgaccttaaa tgacaagtca agtccagaag agattaaggc
   113881 aacctttggt atttcaaaag gccagtttaa aaaagccttg ggtggattga tgaaagctaa
   113941 acgcatcaaa caagacgcca caggaactga attaatagga taaaaatgct ttgccactgg
   114001 caaagttttt tgttacaatg aagaccatta actgaagaaa aaggggatat agagaatgga
   114061 aagagccatt tttgcaggag gttgtttttg gtgtatggtg caaccttttg aggagcaagc
   114121 aggtattttg tcagtcagaa gtggctacac aggtgggcat ctcccaaatc ctagctatga
   114181 acaagtttgt gccaaaacaa caggacatac agaagctgtt gaaattattt ttgaccctaa
   114241 gcaaatcgct tataaagatt tggtagagct ctattgggcg cagacggatc caacagacgc
   114301 ctttgggcaa tttgaagatc gcggggacaa ctaccgtcct gtcatttact atacaacgga
   114361 aagacaaaaa gaaattgcag agcaatcaaa agcaaacttg caagcttcag gacgttttga
   114421 ccaacccatt gtcaccacta ttgaaccagc agagccattt tatctcgcag aggattatca
   114481 ccaaggattt tataaaaaga atcccaagcg gtatgcacaa agcagtgcta ttcgtcatca
   114541 gtttttagag gagaattggt catgagaaaa tcattttaca gctggctgat gacacaacgt
   114601 aaccctaaat caaatgaacc tgtggcgatt ttagcagatt tggtgtttga tgacaccact
   114661 tttccaaagc ataccaatga ttttgaactc attagtcggt atctagaaga tcaagctagt
   114721 ttttccttta atttaggtca atttgatgaa atctgggaag attatctagc acattaatac
   114781 gtggataaaa aagagtcata tcgactcttt tgaagggtta tcacgttatt attacaaaat
   114841 gacatcactt tctttcaaaa aaatgacaag ctactttttt tcttaaaaat atgctatgat
   114901 atagcttaga aaaaaataaa aaggaagcag agatgattat tactaaaaag agcttatttg
   114961 tgacaagtgt cgctttgtcg ttagcacctt tggcgacagc gcaggcacaa gagtggacac
   115021 cacgatcggt tacagaaatc aagtctgaac tcgtcctagt tgataatgtt tttacttata
   115081 ctgtaaaata cggtgacact ttaagcacaa ttgctgaagc aatggggatt gatgtgcatg
   115141 tcttaggaga tattaatcat attgctaata ttgacttaat ttttccagac acgatcctaa
   115201 cagcaaacta caatcaacac ggtcaggcaa cggctttgac ggttcaagca cctgcttcta
   115261 gtccagctag cgttagtcat gtacctagca gtgagccatt accccaagca tctgccacct
   115321 ctcaatcgac tgttcctatg gcaccatctg cgacaccatc tgatgtccca acgacaccat
   115381 tcgcatctgc aaagccagat agttctgtga cagcgtcatc tgagctcaca tcgtcaacga
   115441 atgatgtttc gactgagtcg tctagcgaat cacaaaagca gccagaagta ccacaagaag
   115501 cagttccaac tcctaaagca gttgaaacga ctgaagtcga acctaagaca gacatctcag
   115561 aaggcccaac ttcagctaat aggcctgtac ctaacgagag tgcttcagaa gaagtttctt
   115621 ctgcggcccc agcacaagcc ccagcagaaa aagaagaaac ctctgcgcca gcagcacaaa
   115681 aagctgtagc tgacaccaca agtgttgcaa cctcaaacgg cctttcttac gctccaaacc
   115741 atgcctacaa tccaatgaat gcagggcttc aaccacaaac agcagccttc aaagaagaag
   115801 tggcttctgc ctttggtatt acgtcattta gtggttaccg tccaggtgat ccaggagatc
   115861 atggtaaagg tttggccatt gattttatgg tgcctgaaaa ttctgctctt ggtgatcaag
   115921 ttgctcaata tgccattgac catatggcag agcgtggtat ttcatacgtt atttggaaac
   115981 agcgattcta tgcgccattt gcaagtattt acggaccagc ctacacatgg aaccccatgc
   116041 cagatcgcgg cagtattaca gaaaaccatt atgatcatgt tcatgtctcc tttaatgctt
   116101 aattcatgct atcaaaaaaa ctcacgttta ggcgtgagtt ttttgacaat tctgacagag
   116161 taagccctat aagaggctga gatacgcttt taatacctgt tgtttttctc accctttaga
   116221 cagttttaac gttatgtcta aaagagatgg tttttattag cgcaaatatg ggtttagggg
   116281 taaaataaag gtaattaacc tgatatgatc atgataaagg tagaagaata cctattattt
   116341 cgtgacaact gagcaatctg ccttaccttt ggagtgatga tatcactttg cttgactatt
   116401 caaggaggtc ttgaaatgta ttatactagt ggtaattacg aagcttttgc aacacctcga
   116461 aaacctgaag gggtagatca gaaatcagct tatattgttg gtactggttt agctggttta
   116521 gcagcagctg ttttccttat tcgcgatggg catatggctg gggaacgcat tcatctgttt
   116581 gaggaattgc ctttagcagg tggttcttta gatggtattg aaaagcctca tcttggtttt
   116641 gtgacccgtg gtggtcgtga gatggaaaat cattttgagt gtatgtggga catgtatcgg
   116701 tctattccct cactggaaat tcccggtgcg tcttatttag atgaatttta ttggttggat
   116761 aaggatgatc ctaactcatc caactgtcgt ttgattcaca agagaggaaa tcgtgtggat
   116821 gatgacggcc agtatacgct cggtaaacag tcaaaagaat taatccattt aatcatgaag
   116881 acagaagaat ctctaggaga ccaaaccatt gaagagttct tctcagaaga tttctttaag
   116941 agtaattttt gggtgtattg ggcaaccatg tttgcttttg aaaaatggca ctctgctgta
   117001 gaaatgcggc gctatgcgat gaggtttatc caccatattg atggtttgcc agattttacc
   117061 tccctcaagt tcaacaaata taaccaatat gattctatgg tcaaaccgat tattgcttac
   117121 ctagaatcac acgacgttga catccaattt gatactaaag tcacagatat tcaggtggaa
   117181 caaacagctg gtaaaaaggt agcaaaaacc atccatatga cggtgtctgg ggaggctaag
   117241 gcgattgagc taatacctga tgatttggtt tttgtgacca atggttctat tactgaaagt
   117301 agcacatacg gtagtcatca cgaagtggct aagccaacca aagcgttagg tggttcttgg
   117361 aatttatggg aaaatctagc tgctcaatca gatgattttg gtcatcctaa agtgttttac
   117421 caggacttgc ctgctgaaag ctggtttgtg tctgctacag caaccataaa acacccagct
   117481 atcgagcctt atattgaacg tttgacccac cgtgacttgc acgatggcaa agtgaacact
   117541 ggcggcatca tcactattac agattctaac tggatgatga gctttgccat tcaccgtcaa
   117601 cctcatttta aagaacaaaa agaaaatgag accactgtct ggatttacgg tctttattcc
   117661 aatagtgagg gcaattacgt ccacaagaaa attgaggagt gtacaggtca agaaatcaca
   117721 gaggaatggt tgtaccacct tggggtacct gttgataaaa tcaaggactt agcgagtcag
   117781 gactatatca atacagttcc tgtttacatg ccttatatta cgagttactt tatgccacgc
   117841 gtcaaaggag accgtccgaa agttatccca gatggttcag tcaacttggc ctttattggt
   117901 aactttgcgg aatctccatc tcgagatacg gtctttacga ctgagtattc tattcgtact
   117961 gccatggaag cagtgtatag cttcttgaat gtggaacgag gcatcccaga agtctttaat
   118021 tcagcctatg atattcgtga attgctcaaa gccttttatt accttaatga taaaaaggca
   118081 atcaaggata tggatttgcc aattcctgca ctgattgaga aaatcggaca taaaaaaatc
   118141 aaggatacct ttatcgaaga attgctcaaa gatgctaatc ttatgtaaca tgccttagag
   118201 tagttaaagc tgataagttt aggcttatca gcttttttga tgatttatag aaaagtgata
   118261 aaggaaaagt ctgacgtgaa cgtcacataa gaatttaaaa tttgttataa tgtaagcaat
   118321 aaagatgaaa gaaagaggga ctctatttgc aagagtattc tattgacatt accttaaccc
   118381 atcctgatga tgttttagct ctttttggta gcaacgagcg tcatttgaag ctaatagaag
   118441 ctcatttagg agttattgtt cacgcaagaa ccgagcgagt ccaagtgatt ggtgatgatg
   118501 aagaagctgt ggaattggct cgattgacca tcaaagccct actggttcta gtgggtcgtg
   118561 gcatggttgt caacacatca gatgtggtga cagctttatc tatggcagaa tctcatcaga
   118621 ttgaccaatt tatggcgctt tatgaagaag aaatcattaa agataactat ggtaaggcaa
   118681 tacgagtcaa aacattaggt caaaaaacct atgttgatag tgtcaaacgt catgatgtgg
   118741 tttttggtgt aggacctgca gggacaggga aaaccttctt agctgttacg cttgcagtca
   118801 ctgctctgaa aagaggacag gtaaagcgta ttattttgac gcgtcctgcg gtagaagctg
   118861 gcgaaagcct aggtttttta ccaggcgatt tgaaagaaaa ggtggatcct tacctcagac
   118921 ctgtttacga tgccctttat cacattttag gcaaggaaca aaccacacgc ctgatggaac
   118981 gagatgtgat tgagattgct ccgttagctt atatgcgagg tcgtactctg gatgacgctt
   119041 ttgttatctt agatgaggct caaaacacga ccatcatgca aatgaagatg tttttgaccc
   119101 gtcttggttt taattctaaa atgattgtca atggagatac gagtcagatt gacctccctc
   119161 gaaatgtcaa gtctggtttg attgatgcta ctcagaaatt acaaggcatt aaacagattg
   119221 attttgtcta tttctctgct aaagatgttg tccgacatcc tgttgtggct gatattatca
   119281 aggcttatga aacgtcctca gaggagatga aggacttact aaaacctaag gctagtgacg
   119341 ttgaagctga ttaccagcca ggcttgacaa aataccctgt gatcggtcaa gagcactaag
   119401 acctttacga tgatgtttaa tatggccttt ttaaggagga ttctatggat gatttaacca
   119461 aagctattat ggcagatgag gctaatctct cctataccga aagaggtatt tttcctttat
   119521 atgatgctcc tcaaacagct aggattatta ttgttggcca agctcctgga atagtagctc
   119581 aagaaaccaa actttactgg aatgatcgta gtggcatccg cttacgagac tggctaggtg
   119641 tggacaatga caccttttac cactcaggat tgtttggcat tatccctatg gatttctatt
   119701 atcctggtaa gggaaaatcc ggtgacttac cacctagaga aggttttgcg gctaagtggc
   119761 acccgccatt aagagcattg atgccagaag ttgaattgac gattttggtt ggtcgctatg
   119821 ctcaggactt ttaccttggt aacaaggctt acaaaacctt aactgaaaca gtccgtcact
   119881 ttgaggatta cttgccagac tattttccac ttgttcatcc ttctccaaga aaccaattgt
   119941 ggttagctaa gaacccctgg tttgagcagg atttattacc tatcttgcaa aaacgtgtgg
   120001 aggcaattct aaccaaatag gccctgattt acctagcatt cccattttta aggggcttgt
   120061 ggtataatgg gtaaataaca aatgctgatt gaaaggataa gggaaattat ctgtcagata
   120121 ataatgggtg cccaacatac caaatgaggt gggcagccct tccctaacaa ttaaccttat
   120181 gtatatcgag atgattgacg aaacgggaca agtttcgcaa gagattatgg agcaaacact
   120241 tgatttgctc aattttgctg ctcaaaagac gggcaaagaa gaaaaagaaa tgtctgtgac
   120301 ctttgtgacc aatgaaagaa gtcatgaact caacttagaa taccgagata ctgatcgtcc
   120361 aacagatgtg atttctctag aatataagcc ggaaacgcct attttattta gtcaagagga
   120421 tttggctgct gatcctagtt tggcagagat gatggcagag tttgatgctt atattggcga
   120481 attgtttatt tctattgaca aggcgcgtga gcagtcccaa gaatatgggc actcttttga
   120541 gcgtgaaatg ggatttttag ctgttcatgg attcttacat attaatgggt atgatcacta
   120601 cacccttgaa gaagaaaaag agatgtttac cttacaggaa gagattttga ctgcttatgg
   120661 ccttacacga caataatacc accaaacgga aatggaaaaa cagaaccatt acctcaagct
   120721 tggagtttgc cttgacaggg gttttcacag cttttaagga agaacgcaat ctcagaagtc
   120781 accttttgtc tgcctgttta gcttgtgttg ctggtttatt ttttagcatt tcagccatcg
   120841 aatggttatt tttacttcta gccatttttt tggtcattac cttagaaatt gtcaattctg
   120901 ctattgaaaa tgtagttgat ttggctagtg actatcactt ttctatgcta gctaaaaatg
   120961 ccaaggatat ggcagcaggt gctgttttga tgatttctgg ctatgctgtc ttgacaggac
   121021 ttattatttt tattcctaaa atttggaata ttttcgttca ttaaaaagaa aggaatgggc
   121081 tatcctatgt gatgatggca taggagaata aggaaaggac aagacggtta agcttagtga
   121141 caagcttgat ctgaagccct accgttaagg cccgtaatta tctatgttta aatcaggctt
   121201 tgtagccatt cttggtcgtc caaatgttgg caaatccacc tttttaaatc acgtcatggg
   121261 gcaaaaaatt gccatcatga gtgacaaggc tcagaccacc cgtaataaaa ttatgggcat
   121321 ttacaccaca gaaacagaac aaattgtctt tattgatacg ccaggtattc ataaaccaaa
   121381 gaccgccctt ggtgatttta tggttgaatc tgcttatagt actttacgtg aagttgagac
   121441 ggttcttttc atggttcctg ccgatgaaaa gcgtggtaag ggtgacgaca tgattatcga
   121501 gcggctaaaa gcagctaaga ttcccgttat tttagtcatc aacaaaattg ataaggttca
   121561 tccagaccaa cttttggaac agattgatga cttccgtagc caaatggatt ttaaagaagt
   121621 ggtcccaatt tctgccctag aaggtaataa tgtgccaacc ctaatcaagt tattaactga
   121681 taatcttgaa gaaggtttcc aatattttcc agaagatcag attactgatc atccagaacg
   121741 tttccttgtg tcagaaatgg ttcgtgagaa ggtactgcat ttgacgcaac aagaggttcc
   121801 acattccgta gctgttgttg tcgaatccat gaagcgagat gaagagactg ataaagtgca
   121861 tatccgtgca accattatgg tagaacgcga tagccaaaaa ggtattatca tcggtaaaca
   121921 aggagccatg ctcaaaaaaa tcggaaaaat ggcgcgccgt gatattgaac tcatgttagg
   121981 tgacaaggtc tacttagaaa cgtgggtcaa agtcaagaaa aactggcggg ataaaaagct
   122041 tgatttagct gattttggct ataatgagaa agaatactaa catagtaaag cgagatcata
   122101 tgccacaaga ctacattact tatatccgct ccaaagttgg gcatgataag attattctta
   122161 actttgctgg tgggattttg atcaatgatg acggcaaggt gctgatgcag ttgcgtggtg
   122221 ataagaaaac ctgggctatt cctggtggca ctatggaact gggtgagagc tctttagaga
   122281 cttgcaaacg tgagttctta gaggaaaccg gaattgaggt tgaagctgtt cgcttactga
   122341 atgtttacac tcattttgag gaagtttatc ccaacggtga tgctgttcag actattgtct
   122401 ttatctatga actaacggct gtttctgata tggctattga taactttcat aatgaggaaa
   122461 cgctcaagtt acagtttttc tctcatgagg agatagcaga gttagagagt gtctcagcca
   122521 aacatcgcct gatgttagag gaatatttta gtgatagctt tgctatgggg cattaagaac
   122581 tctctaggac agttggagta tttttggaga ttggcttgtt aaaaaaattt ttgaaagacg
   122641 atgtttcgag agcttatgct ctcttttttt gcttccaatt tttctgatta agtctgaata
   122701 attttgttaa atgttaacag gattttcttt ccaattgata ctagcagaca tcaaacattt
   122761 gttttagagt tatgacgaat tgccacctag ccatgcatga cttaggcaag ttgaacctaa
   122821 ctgtggcaat agacttggaa ggggtgacaa gaatcatttc ctaaaagaat tgatgaagtg
   122881 cctatccatt attcgaattg taaagttcgt ctaagtaaag ttgaatttga tctcgaatgg
   122941 actttaatga tttatgactt gttgtgtcaa taacaccaaa aactcgataa tgatttttaa
   123001 atatttcctc gtaattaata tgatttccga ttagaataat atgagcatga ggataacgca
   123061 tacgtatttc gtttagaagg tcatatactt gctcagattt aaaaaagtat gatttatgat
   123121 aaaataaacc tgacatttgt atttataatc taagtttttc ccactaataa tttaagtttt
   123181 tagaaagtat ctcttgaggt aatagttaat atagatagat atcatatatc ctaaaagaga
   123241 acgatgtaag acttgaataa ctatcataat tttctccacg tattgaacaa tcaattgact
   123301 atgtccatca tcaacaaggt caaacgttag ctgaagactc ctttattttt aaagatgcca
   123361 agactcaggt tcagattcca ttcagattcc atttgcagac ttactttata ttgaaacgtc
   123421 atatattgct cataaattgg ttctttattc tactagagaa aggattgaat tttatgggga
   123481 gttatctgaa atcgttaagc aagaaccaag attatttcaa tgccatcgat catttgttgt
   123541 taatccctac aatatatctt caatacaacg attagaacgt aaggtttatt taaaaaaacg
   123601 gttcatcttg tctagtatca aggctaaaag ttactgctct aaaagaagca gttgaaaatc
   123661 tacataataa ggagacttag atgagtagca tcttctttct agcacttact tttactcatg
   123721 tcattatttt gataatttta catgctaaag tatatgtata taaagtaact gtgaaaaatc
   123781 tttcgcttta tacgcttttc tttttttata ttctgcccag tttggaaata ggtatcgaat
   123841 ttcaagatat gaatatcgtt tctgatattt atcagaatgt cctcttgact agtggagtga
   123901 ttagcaccta gggttaagtt ttctaagata gatccactaa agatatgagc ttgttggggg
   123961 agatagttga tatgctgacg aagcactttt ttatcaatca ttttaagatt ttgatgatta
   124021 atagaaatct gtcccttgta aggttcaaag aaattaacaa tcattttagc taatgttgtc
   124081 ttgccagaac cactaatacc aactatactg actttttcac cctccttaat ggtcaaactg
   124141 atatcagata aggtatcacg accaaagccg tatttataag acaagtctgc aaattagata
   124201 tctccatata gataataggt atctgttaat gcctgttctt tttggaactc agatttaacc
   124261 aggtaaactt cattgagacg attattagct accttagcgg attgcagttt agtttgaaga
   124321 ttaatgatat tttaccattc ataactagtc gtgcacccac ccataagata gtaacgttta
   124381 aaatgagttg tgctccttgc tttagactac tttgtagaat acttacttaa cttaaaagat
   124441 ttatccaaat agtctacaaa ttcactatcg attttctgat aacgaatttc ctcgctagtc
   124501 aatgatttga ttgtttcaat accattaata tcttcgataa tagcagagct ggccatggaa
   124561 ttactctgca tgacattgtt attcatcttt tcaaaaggtt tcataaaagt aaaaatgatg
   124621 ataatgtaga ttgggataga aattaatgat agaagaaata ggttagtgtt ttgtacgagt
   124681 aacacaccac ctacaatact taaaatagag acatctaaaa atagagatag aattgtagaa
   124741 gcaagtgtat caataatagc attagcatct gtaaaacgtg agatgatttc tcctgtccga
   124801 cgtgttacaa agaaagacat gggaagctca aaaatatgac gaatatagga taaaataaca
   124861 tcaatgctta atcgctgact cagtacagtc aggagataat ctcgcgaaaa actcatcatc
   124921 tgttgtagga tataggtaac gataagtcca attgagatta taccgagtgt tggcttcatc
   124981 tgatttggaa tatattcatc ccaaatacct tgtagatagt aggaaccacc aatatttatc
   125041 agggtaacta agaggctcgc taaaacgata tagaagatta aggactcttg tttaaaaatt
   125101 agaggtagaa aactcattaa gccattcttt ttatccttgt gaggtttata gccaggttca
   125161 ggtgctaaaa agatagcaac ccctgtctat tcaggagcaa atttttcttt gctcattttg
   125221 gttactttaa cggagggatc tggatctcca atgatgaaat gttcttttca aagcccatct
   125281 ccttggccgc ttttacgatt ccaagggttg ttgttccttc tttattagtc tttgccaatt
   125341 ctctcagatg tgtcaaagag tagtcagacc cgtagaattt tgcaatcgaa gctagagcag
   125401 caattccaca atctcttgca tcaatttgtg gtacaaacgt acgtttacat gatgtcatta
   125461 atatatttcc ttccagtaaa ttacaaattc attattgcaa aactactgat aagaaattcg
   125521 aaaattctta aatggtatct agtatatcct gaatggtatt ttaaaattaa aagtaataag
   125581 tttctagtga ttattttcta attcgaaacg attaaaaaac tatgaaaaaa atcatttcat
   125641 gatgaaaaaa gaacatttga agattttacg gggcacagat ttcttaagat gctatactga
   125701 acatgtcaag gttgcaacaa gacataataa aaaattatat aaggagatat tcgttatgaa
   125761 tacaacaatt aaacaatttg aaattatgga tgaggccatg cttactggta ttgaaggtgg
   125821 ttgttcatgg catgggttag ctcaggcagc tgtttttact ggtgctggaa atggatttag
   125881 attaggtgtt aaaacaagga cttggcaagg agctgcagct ggagcagctg gtggactggt
   125941 cattggagga gtcggttatg gggcgacttg ttggtggtaa taaccatgga tatcaaaagt
   126001 tttttgcttg gtttagttat tggtttactt tgcccaattt tcgacaatat attattgaat
   126061 atcctgaaaa attggaaaaa ccgatagaag acactaagat ggggctttac tcagtttata
   126121 taggtgatct ttaaggattt aacatagctt ggatgtgata ggtctcgttg gaataagaaa
   126181 aagtatactg gtaaatgtta aaaaatagga gcaaatagaa tgagtggtgt ctttaagaag
   126241 tgtcttacct ttattatgtc aattatattc tctatattta tgactatttt tgttcaaact
   126301 ccagttgttg cgacatttaa caatgaacgg attaatctta ggcaagggat caatggagac
   126361 tttttaagag taataatttg cattattttt ataatacttt gcttttattt tctgtcactc
   126421 ttagcgaaat gtcttatcag ccagtaaagt tcatattatt ttttttacga ctgtagtttc
   126481 tcaaccaatc ttggaggaga ttctatttcg aggaatactg caagaaaagt tatcacgcgt
   126541 ttcgttttgg ttaagcatca ttgtgacatc tgtaatattc tcgtatattc atggaaatga
   126601 cactatattg aatactcaat tcatcagttc tttgatatat ggaatggctt atcaaacaag
   126661 taaggattta agatttccta ttattaacca ttctctgcag aatttaatag tacttcttac
   126721 agttgttttg ctaaagtaag tagtgagaat taataaaaat aactgggata attatagtaa
   126781 tgaaaagatt ttgacaatga caaaataatt tagtgaaata aatatgactg agctaacaag
   126841 tatttcaggt ggctcccaaa aaagttattg tgttggtttg attacaggac gcatctggaa
   126901 gaagaagctt cttgggcaaa aaattgtagt ttcagattac actttccgtt aatgttatta
   126961 aagatgcggt tgactatgtt gtcggatttg tagcttcgtt agtataataa gcattttatg
   127021 tcaaagccaa gctatgtata ctgaccttgc tttctaggga ataggagaga gaacttagag
   127081 gcatttcgct ggctttgcat tttgtttatg actatatctt aaacggacat cgaaacatct
   127141 tgaatggtag agtgagtctt ggactcatgg atataaaatt aagataatat gggtgttttt
   127201 gaaattatga atgttaaaaa gacttcccat ttaggaaagt taaatgactg tttaggaaat
   127261 agtgcaggat ttttttaaga agcgctatac tgaatatgtc aaggttgcaa ctggacaaaa
   127321 tataaaaatt atataaggag atattcatga tgaatacgaa aacaatggaa caatttgaag
   127381 tgatgaactc tgaaatgctt gctggtgttg aaggaggctg gggcggttgg ggagaagcaa
   127441 ttgccggtct attaggaggc tttgctcctt caccaacatt agatcaatta aatggcaaat
   127501 ggccaattag aaaaccttcc aaaccttgta gaccttacgg aactggtggg acacctaatg
   127561 cgtgtaatgg tttataaatt aggacatatt taagtgatta tgcaataaag gaagtggagg
   127621 tagatatgct gactctatac aaaagacaaa tcgcagaagt ttgggagatt gggagagaaa
   127681 cgcctcagcc agagtgggta cgtgatgctt ttcgcaagaa ttacatctgt tggttggatg
   127741 agcatgttcg tattctcatg actggactaa atccttcgct gacaacaaat ttaaagattg
   127801 gtgcaacagg aacagtaggt ggaggatttg ctggatatgg tatgtatgtc cttggttatc
   127861 caggtgattt cttggatgtg accaaccatc gagttatttc tgccaaaaaa ttccataaag
   127921 aatatcagat tattgatgga tagaaaaagt agactatgaa cttttatgac tggtttaatt
   127981 ttgagggttt acaacaaaaa ggagctcttt ggaagattgt aggaagtatt ttctttgtcg
   128041 gttttcattt attcatcatc tatttggtac aaagataatt agttcaactt taaaaattca
   128101 tcccaatagt ctttatcgat ggattcaaga atatgaaaaa tatggagaaa gtgcgttccc
   128161 aggacatggg agcgcacttc gtcatgctca atttgagaca aaaaaacttg aaaaagagca
   128221 caaactgcta caggaggaat tagctcttct aaaaaagttc caggtctttt tgaagccaaa
   128281 ccggaaataa aatttcagtt tctgaaggaa aatagtgtta gcttgaatag tcatcacgcc
   128341 tgtcaaactc ttcaagtctc ccgttcaggt ttctatgctt atttaaacgt cgtccctctt
   128401 caaggcatgt tgagaatgaa gctttgaagg aaatgattaa agccattttc tatgaacata
   128461 aagagcgtta cggaagtgta cgaattaccc aagaactttg tagacgtggc atccatgtca
   128521 attataaacg tgttggtaga ctccttcatc agctaggtct ctatgctaaa ggaagtcgat
   128581 atcaatataa atactataac cgtcgacgtt cttcatgaac tcgtcccaat cttgttaatc
   128641 a
//
LOCUS       DATTYN010000003       118936 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.03, whole genome shotgun sequence.
ACCESSION   DATTYN010000003 DATTYN010000000
VERSION     DATTYN010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 118936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118936
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.03"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(225..773)
                     /gene="raiA"
                     /locus_tag="VB649_000269"
     CDS             complement(225..773)
                     /gene="raiA"
                     /locus_tag="VB649_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEP1669253.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFAKDQEIDARVNL
                     KVYRERSSKVEVTIPLDSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KVPTGQVFTTEFEAEEVDEIPEVQVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDS
                     EDGATNILYRREDGNLGLIEAK"
     gene            complement(853..1518)
                     /locus_tag="VB649_000270"
     CDS             complement(853..1518)
                     /locus_tag="VB649_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEP1669254.1"
                     /translation="MICLLCQQISQTPISITEIIFLRRISSPICQQCQKSFQKIGKSV
                     CATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNAAMKAYFSQYKFQGDYLLRKVFA
                     VELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
                     SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLS
                     IAR"
     gene            complement(1490..2815)
                     /locus_tag="VB649_000271"
     CDS             complement(1490..2815)
                     /locus_tag="VB649_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP1669255.1"
                     /translation="MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRCH
                     YQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPPMHFPKGNYLVWSGQLTAYQEII
                     SQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
                     LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQL
                     HYAASQALKEGGAKILLTATSTRTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFN
                     LFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAILKELLPAEQIACVS
                     SQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDVFVLGSHHRVYSSQSLVQIAG
                     RVGRSIDRPDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN"
     gene            2871..3503
                     /locus_tag="VB649_000272"
     CDS             2871..3503
                     /locus_tag="VB649_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEP1669256.1"
                     /translation="MEHFKTIKASGFFEESIKKSRFICHIKRVSTEEDGKNFVNAIKK
                     EHYKANHSCFAMIIGNNRQIKRSSDDGEPSGTAGIPILSVLEKQCLTNVVVVVTRYFG
                     GIKLGTGGLIRAYSNMTATAIKRFGIIEVKQQIGLEITLSYPQYQLYSNLLDQLALTE
                     TETKFSDTIKTTLYCDTERVENLIDTLTNYYHGQISCEKIGSKVIEFPCD"
     gene            3631..4572
                     /gene="cysK"
                     /locus_tag="VB649_000273"
     CDS             3631..4572
                     /gene="cysK"
                     /locus_tag="VB649_000273"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEP1669257.1"
                     /translation="MTKIYKTITELVGQTPIIKLNRLIPNEAADVYVKLEAFNPGSSV
                     KDRIALSMIEAAESEGLISPGDVIIEPTSGNTGIGLAWVGAAKGYRVIIVMPETMSLE
                     RRQIIQAYGAELVLTPGAEGMKGAIAKAETLAIELGAWMPMQFNNPANPSIHEKTTAQ
                     EILEAFKEISLDAFVSGVGTGGTLSGVSHVLKKASPETVIYAVEAEESAVLSGQEPGP
                     HKIQGISAGFIPNTLDTKAYDQIIRVKSKDALETARLTGAKEGFLVGISSGAALYAAI
                     EVAKQLGKGKHVLTILPDNGERYLSTELYDVPVIKTK"
     gene            complement(4590..4967)
                     /locus_tag="VB649_000274"
     CDS             complement(4590..4967)
                     /locus_tag="VB649_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEP1669258.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALDNGTTGLIHISEIKTGFIDDI
                     DQLLAIGNQVLVQVIDIDEYSKKASLSMRTLAEEKQHFFHRHRYSNSRHKIGFRPLEE
                     QLPQWIEESLQFLKKNTKKSLEP"
     gene            complement(4967..6367)
                     /locus_tag="VB649_000275"
     CDS             complement(4967..6367)
                     /locus_tag="VB649_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEP1669259.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKDTGYMPESIQRVFKALKA
                     KGILVGIASGRARYGVPQEVQDLHADYCVKLNGAYVKDDAKTIIFQAPIPADVVVAYK
                     KWADDMGIFYGMAGRHEAVLSARNDMISNAIDNVYAQLEVCPDYNEYHDVYQMWTFED
                     KGDGLQLPAELAEHLRLVRWHDNSSDVVLKGTSKALGVSKVVDHLGLKPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPLLQEKADFITKKVEEDGILYALEELGLIDKELQFPQL
                     DLPNHKGPKATIKTNHGDMTLVLFPDHAPKTVANFLGLAKEGYYDGIIFHRIIPEFMI
                     QGGDPTGTGMGGQSIYGESFEDEFSDELYNLRGALSMANAGPNTNGSQFFIVQNSKIP
                     YAKKELERGGWPAPIAASYAANGGTPHLDRRHTVFGQLVDETSFQVLDLIAGVETGAQ
                     DKPKEDVIIETIEVFD"
     gene            complement(6404..7045)
                     /locus_tag="VB649_000276"
     CDS             complement(6404..7045)
                     /locus_tag="VB649_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1669260.1"
                     /translation="MSKIKVILVDDHEMVRMGLKSFLNLQADIDVVGEASNGREGVDL
                     ALALKPDVLVMDLVMPELGGVEATLEVLKKWKEAKVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN"
     gene            complement(7038..8042)
                     /locus_tag="VB649_000277"
     CDS             complement(7038..8042)
                     /locus_tag="VB649_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1669261.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFNYLRNHLWQVER
                     LGFSILLLIVSVTLLLLLLWIIMDDNSKRNINQNLKYILNNRRLYLDETSEINTNLSR
                     LSKKMSHLTANMQKKESAYILDSQEVVKQERKRIARDLHDTVSQELFASSLILSGISM
                     SLEQLDKTQLQTQLTTVEAMLQNAQNDLRILLLHLRPTELANRTLSEGLHMILKELTD
                     KSDIEVIYKETIAQLPKTMEDNLFRIAQEFISNTLKHAKASRIEVYLNQTSTELQLKM
                     IDDGVGFDMDQVRDLSYGLKNIEDRVNDLAGNLHLISQKGKGVSMDIRLPIVKGDDDE
                     "
     gene            complement(8039..8731)
                     /locus_tag="VB649_000278"
     CDS             complement(8039..8731)
                     /locus_tag="VB649_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEP1669262.1"
                     /translation="MKKFQFFLLIECILLAMGIMTILDNDLSSFILILVLILLALRFY
                     NQDSRNNFLLTVSLLFLFLIFMLNPYIIMAVLLGIVYIFINHFSQVKKKNRFALIRFK
                     EEKIEVNNTKHQWIGTANYESDYYCFDDINIIRISGNDTVDLTNVIVTGMDNIIVIRK
                     IFGNTTILVPIDVTVTLDVSSIYGSVDFFRCQQYDLRNESIKLKETDNQSLKKVKIIV
                     TTIAGNVEVDRR"
     gene            complement(8854..10752)
                     /gene="pknB"
                     /locus_tag="VB649_000279"
     CDS             complement(8854..10752)
                     /gene="pknB"
                     /locus_tag="VB649_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEP1669263.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGADLKRYI
                     QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIEENHNVPQALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYN
                     RSRERKIIFEDVESTKPLPKVASGPTASVKLSPPTPTVLTQESRLDQTNQTDALQPPT
                     KKKKSGRFLGTLFKILFSFFIVGVALFTYLILTKPTSVKVPNVAGTSLKVAKQELYDV
                     GLKVGKIRQIESDTVAEGNVVRTDPKAGTAKRQGSSITLYVSIGNKGFDMENYKGLDY
                     QEAMNSLIETYGVPKSKIKIERIVTNEYPENTVISQSPSAGDKFNPNGKSKITLSVAV
                     SDTITMPMVTEYSYADAVNTLTALGIDASRIKAYVPSSSSATGFVPIHSPSSKAIVSG
                     QSPYYGTSLSLSDKGEISLYLYPEETHSSSSSSSSTSSSNSSSINDSTAPGSNTELSP
                     SETTSQTP"
     gene            complement(10749..11489)
                     /locus_tag="VB649_000280"
     CDS             complement(10749..11489)
                     /locus_tag="VB649_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEP1669264.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVE
                     AVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRN
                     IITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQ
                     EMIDLANLRGGLDNITIALVHNESEDVE"
     gene            complement(11527..12849)
                     /gene="rsmB"
                     /locus_tag="VB649_000281"
     CDS             complement(11527..12849)
                     /gene="rsmB"
                     /locus_tag="VB649_000281"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEP1669265.1"
                     /translation="MADNWKKSTRGKALLVIEAIFDQGAYTNIALNQQLSNKALSAKD
                     RALLTEIVYGTVSRKISLEWYLAHYVKDRDKLDKWVYYLLMLSLYQLIYLDKLPAHAI
                     VNDAVGIAKNRGNKKGAEKFVNAILRQFTSHPLPDMETIKRRNKYYSVKYSLPVWLVK
                     KLEDQFGSDRAVAIMESLFVRSKASIRVTDPLKLEEVAEALDAERSLLSATGLTKASG
                     HFAASDYFTNGDITIQDESSQLVAPTLNIDGDDIILDACSAPGGKTSHIASYLKTGKV
                     IALDLYDHKLELVKENANRLGVADNIETRKLDAREVHRHFEKDSFDKILVDAPCSGIG
                     LIRRKPDIKYNKESQDFNALQAIQLEILSSVCQTLRKGGIITYSTCTIFDEENRQVIE
                     AFLQSHPNFEQVKLNHTQADIVKDGYLIITPEQYQTDGFFIGQVRRVL"
     gene            complement(12839..13774)
                     /locus_tag="VB649_000282"
     CDS             complement(12839..13774)
                     /locus_tag="VB649_000282"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEP1669266.1"
                     /translation="MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKD
                     IKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTILLDSVS
                     FAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETD
                     NVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEQEKLDWTMSN
                     QEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVITTGQGA
                     LSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR"
     gene            complement(13836..16220)
                     /locus_tag="VB649_000283"
     CDS             complement(13836..16220)
                     /locus_tag="VB649_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEP1669267.1"
                     /translation="MEKVAHVIVDIPLMQTDKPFSYGIPKELVSLVQLGSRVHVPFGK
                     GNRLLQGFIIGFGQEDSSSLKLIQTVLDPEPVLNQEQLTLADQLRKTVFSYKITLLKA
                     MIPNLLNSNYDKVLRPESGLKKPDRDFLFEGKPSVLYSTLDREKEKIALKAIQAGHIT
                     VSYLAKDKKNLKTEKYYHVDLDALAVHPISSRAKKRQLLKDYLLTHTKEAKLATLYQA
                     FSRDVVAYFVTNHLIRIDERPIDRSEPYFDQIKPSSFLTLNEQQASAVTEIVEQIGKP
                     SKPFLIEGITGSGKTEVYLHIIEAVLKQDKTAIVLVPEISLTPQMTSRFISRFGKQVA
                     IMHSGLSDGEKFDEWRKIKTGQAKVVVGARSAIFSPLERIGAIIIDEEHESTYKQESN
                     PRYHAREVALLRAKHHQAVVVMGSATPSIESRARASKGVYHFIQLTQRANPLAKIPEV
                     TIVDFRDYIGQQAVSNFTPYLIDKIKERLVKKEQVVLMLNRRGYSSFVMCRDCGYVDK
                     CPNCDISLTLHMDTKTMNCHYCGFQKPIPITCPECYSNSIRYYGTGTQKAFDELQGVI
                     PEARILRMDVDTTRKKRSHKTILDSFGRQEADILLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLNLPDFRASEKTFQLLTQVAGRAGRAHKPGEVLIQTYNPDHYAIQLAKKQDFEAFY
                     RYEMAIRRQMAYPPYYFTVGITLSHRLEASVVKKAYQVTELLKSHLSDNIKILGPTPK
                     PIARTHNLYHYQILLKYRFEDNLEETLNRILDWSQEADNRHLKLIIDCEPQQFL"
     gene            complement(16285..16602)
                     /locus_tag="VB649_000284"
     CDS             complement(16285..16602)
                     /locus_tag="VB649_000284"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEP1669268.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSV
                     KSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(16618..17253)
                     /gene="gmk"
                     /locus_tag="VB649_000285"
     CDS             complement(16618..17253)
                     /gene="gmk"
                     /locus_tag="VB649_000285"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEP1669269.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALM
                     REYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK"
     gene            complement(17363..18970)
                     /locus_tag="VB649_000286"
     CDS             complement(17363..18970)
                     /locus_tag="VB649_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEP1669270.1"
                     /translation="MVNIILLIVSALIGLILGYALISIRLKSAKEAAELTLLNAEQEA
                     VDIRGKAEVDAEHIKKTAKRESKANRKELLLEAKEEARKYREEIEQEFKSERQELKQL
                     ETRLAERSLTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQLQVEKLEEEKKAELE
                     KVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTVKTAKDLLAQAMQRLAG
                     EYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVILSGFDPI
                     RREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPDL
                     IKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDRE
                     VEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGARN
                     ESMENYIKRLRDLEEIATSFDGVQNSFALQAGREIRIMVQPEKISDDQVVILSHKVRE
                     KIENNLDYPGNIKVTVIREMRAVDYAK"
     gene            complement(19100..19996)
                     /locus_tag="VB649_000287"
     CDS             complement(19100..19996)
                     /locus_tag="VB649_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP1669271.1"
                     /translation="MDIKQIRYFIAIVENHFNLSQAAELLYVSQPTLSMMINDFEKRE
                     NVKLFKRKRGRIIGLTYLGDNYYKDAQKVLSLYDDMFLKLHDHSKGLMGSINIGIPPL
                     ILSVVFSEVMPKLILENPGIQFNVKEIGAYQLKNELLVGNVDVAVLLSPTGIADNLVE
                     TYEIQRSELSVCLSPRHRLASKKVIQWEDLTDEQLALFDPSFMVHHLVLEACERHQVR
                     PNIILTSSSWDFMLNSTKINHNVLTICPKPITELYQLKDIKCIPMERPISWRVVLTRL
                     RKKSYSEIEAYIMDDLLQSFFK"
     gene            20197..21384
                     /locus_tag="VB649_000288"
     CDS             20197..21384
                     /locus_tag="VB649_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEP1669272.1"
                     /translation="MKNIVIVEALRTPIGAFGGSLKSVSAVELGTTVLKKILDKTQVK
                     PEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSI
                     MLGDADIVIAGGVENMSQAAYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
                     AENVAQKYGISREEQDQFALESQEKAARALENHRFADEIVPVSVPQRRKDPLIVTTDE
                     YPKVDTSLEKLQQLRPAFLPKEGTVTAGNASGINDGAALLMLMTEEKALELGLTPLVT
                     IESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKL
                     NPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVK
                     NNT"
     gene            21408..22058
                     /locus_tag="VB649_000289"
     CDS             21408..22058
                     /locus_tag="VB649_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEP1669273.1"
                     /translation="MCKEITIKEAVAHVKDGDTIMVGGFMTNGTPEKLIDALVEKGVK
                     DLTLICNDAGFPDKGVGKMVANKQFSTIIASHIGLNREAGRQMTEGETVIDLVPQGTL
                     AERIRSGGFGLGGFLTPTGIGTEVAKGKEVITIDGKDYLLEKPLKADIALIFANKADK
                     NGNLQYAGSENNFNHVMAANAKTTIVEAREIVDVGQMDPNFVHTPGIFVNYLVKGA"
     gene            22060..22719
                     /locus_tag="VB649_000290"
     CDS             22060..22719
                     /locus_tag="VB649_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEP1669274.1"
                     /translation="MGTSATVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANY
                     IPEGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRG
                     GHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
                     ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKT
                     N"
     gene            22752..23531
                     /locus_tag="VB649_000291"
     CDS             22752..23531
                     /locus_tag="VB649_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEP1669275.1"
                     /translation="MTHTKEVAFITGAASGIGKQIGETLLKEGKTVVFSDINQEKLDQ
                     VVADYTKEGYDAFSVVCDVTKEEAINAAIDTVVEKYGRIDILVNNAGLQHVAMIEDFP
                     TEKFEFMIKIMLTAPFIAIKRAFPTMKAQKHGRIINMASINGVIGFAGKSAYNSAKHG
                     LIGLTKVTALEAADSGITVNAICPGYVDTPLVRGQFEDLSKTRGIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGVTGQACILDGGYTAK"
     gene            23602..24933
                     /locus_tag="VB649_000292"
     CDS             23602..24933
                     /locus_tag="VB649_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEP1669276.1"
                     /translation="MEIIGSLGVLVGVIVIIYLSVKEVNIIIAAPLATSLVILFNQMD
                     PTKTLLGKEPNQFMGALSTYILNYFAIFLLGSILAKLMETSGATTSIADYILKKVGHD
                     SPYKVLVAIFLISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLDTSLTAAAIPSIVGSIGCVTFGLFYMKYCLAKSMARG
                     ETYATYAFDNEIQVKTKNLPHFLASILPLLLLIIIALTGSLFGNDFFKKNIIFIALLA
                     AILTASWLFRQFIPNKIAVFNLGASSSIAPIFATASAVAFGAVVMIAPGFTFFSDLIL
                     NIPGNPLISLAVLTSSMSAITGSSSGALGIVMPNFAQYYLDQGLNPEMIHRVATIASN
                     IFTIVPQSGVFLTFLALTGLNHKNAFKETFITVSVSTFIAQVIMIAFDLFS"
     gene            25007..25489
                     /locus_tag="VB649_000293"
     CDS             25007..25489
                     /locus_tag="VB649_000293"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEP1669277.1"
                     /translation="MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLV
                     QPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKV
                     IKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
                     "
     gene            complement(25633..27102)
                     /locus_tag="VB649_000294"
     CDS             complement(25633..27102)
                     /locus_tag="VB649_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669278.1"
                     /translation="MSEESKEVEVTKESQTLGLNEAKSMTIGEAVRKQSEIKAGVTKD
                     DSILDKYIKQHRDEVSSQKFDAKYTELDTASLDNFIKKQREALSKAGLVDDEPVSAES
                     AEQDSTLVEEVAEDLAPMETTAVVTGIPVEATVPVLDLDPSERVIPEPQITKEEPKRD
                     QFLSEDSHHPAKQNTKKGWLIALFLLLLAILAVVFGWNHFLRQDSGKTTQTASKQTKT
                     SLQTDSARKATRLKAAAKAFEKQYGTFYTDATKSKLKNSAFATLPDLEAALKALEGSA
                     YYDKAKAKVDSLKKAIAAITAVNGKFVSDVVVDGEKVSAEVKADANFDDLSSATLTTG
                     NANLDAVLQASITEGRQQLASKAEAAKAANEQAAQAQAAQGQSTSVAPSGYGLTSYDP
                     ASLQRHLSRVPYNQDVIADRANPSWAFNPGVLEKIVATSQARGYISGNQYILEPVNII
                     NGNGYYNMFKPDGTYLFSINCKTGYFVGNGKGYADALDY"
     gene            complement(27116..28270)
                     /locus_tag="VB649_000295"
     CDS             complement(27116..28270)
                     /locus_tag="VB649_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEP1669279.1"
                     /translation="MKETFRLVATAAAGLEAVVGKEVRALGFDCQVENGKVYFEGDVE
                     AIVKTNLWLRAADRIKIIVGQFPARTFEELFQGVFALDWENYLPLGAKFPISKAKCVK
                     SKLHNEPSVQAITKKAVVKKLQKHFHRPEGVPLQEVGSTFNIEVSILKDQATIMIDTT
                     GSSLFKRGYRVQKGGAPIKENMAAAILALSNWFPDKPLVDPTCGSGTFCIEAAMIGMN
                     IAPGFNRSFAFEEWSWVDKDMVQQVRDDAEQEANYEIELDISGFDIDGRMIEIAKSNA
                     EEAGLSDVITFKQMRLQDFRTDKINGVVISNPPYGERLLDDKAVDILYNEMGQTFAPL
                     KTWSKFILTSDELFELKYGQKADKKRKLYNGTLKVDLYQFYGERVKRHLI"
     gene            complement(28333..28701)
                     /gene="rnpB"
                     /locus_tag="VB649_000296"
     ncRNA           complement(28333..28701)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VB649_000296"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(28715..29041)
                     /gene="gpsB"
                     /locus_tag="VB649_000297"
     CDS             complement(28715..29041)
                     /gene="gpsB"
                     /locus_tag="VB649_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEP1669280.1"
                     /translation="MTSIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYENFNA
                     QIEALKAENEALKKAKFQARNTVSATVQQPVPQPTRVAQSATNFDILKRISKLEKEVF
                     GKQIIE"
     gene            complement(29160..29675)
                     /locus_tag="VB649_000298"
     CDS             complement(29160..29675)
                     /locus_tag="VB649_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEP1669281.1"
                     /translation="MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVD
                     WFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDKWNEKNQEVLSQFRAVDF
                     VKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPYYQLLLL
                     TFDRLNDMSQS"
     gene            29756..30364
                     /gene="recU"
                     /locus_tag="VB649_000299"
     CDS             29756..30364
                     /gene="recU"
                     /locus_tag="VB649_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEP1669282.1"
                     /translation="MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDY
                     YLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAK
                     ETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQID
                     NGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN"
     gene            30351..32516
                     /locus_tag="VB649_000300"
     CDS             30351..32516
                     /locus_tag="VB649_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP1669283.1"
                     /translation="MITIKNPKILKWLKYVLSAILSLIILVIIIGGLLFTFYISSAPK
                     LSEAQLKSTNSSLVYDGNNNLIADLGSEKRENVTADSIPINLVNAITSIEDKRFFNHR
                     GVDLYRIFGAAFHNLTSQTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKSYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYLHPEAAQNRRNVVLQQMYMEKHLTKAEYETAIATPVAEGLQSLQQRSTYPKYMD
                     NYLKQVIEEVKKETNKDIFTAGLKVYTNIIPDAQQTLYNIYHSGDYVYYPDQDFQVAS
                     TIVDVTNGHVIAQLGGRNQDENVSFGTNQAVLTDRDWGSTMKPITAYAPAIESGVYTS
                     TAQSTNDSVYYWPGTTTQLFNWDLRYNGWMTIQAAIMLSRNVPAVRALEAAGLDYARS
                     FLSSLGINYPEMHYSNAISSNNSSSDKKYGASSEKMAAAYAAFANGGIYHKPRYVNKV
                     EFSDGTSKTFDEKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAKIGEKYGLYPDYVGTLAPDENFVGFTKRYAMAVWTGYKSRLTPVYGSSLEIA
                     SDVYRSMMTYLTNGYSEDWTMPNGLYRSGGFLYLSGTYASNTDYTNSVYNNLYSNNTT
                     TASSQTTSDDTSSSNDTSNSTNTDNNSNHPSTDDKKTTH"
     gene            complement(32981..34318)
                     /gene="pepC"
                     /locus_tag="VB649_000301"
     CDS             complement(32981..34318)
                     /gene="pepC"
                     /locus_tag="VB649_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEP1669284.1"
                     /translation="MSALTETFTEQLFAHYEANAKFSAIENAVTHNGLLKSLETRQSE
                     VDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLITEFKLENFELSQAHTFFWD
                     KYEKANWFMEQVIATADQELTSRKVKFLLDVPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESISSSNSRELNQYLNKLLRQDAQILRDLIASGANADQVEDRKAELLQEIFNFLAMTL
                     GLPPRHFDFAYRDKDDHYHVEKGLTPQAFYDKFVGLKLSDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSREVRYLNLDMKRFKELAIKQMQAGESVWFGSDVGQVSDRQKGILATN
                     TYDFEASMDINLSQDKAGRLDYSESLMTHAMVLTGVDLDETGKPLKWKVENSWGEKVG
                     DKGYFVASDAWMDEYTYQIVVRKEFLTADELAAYEKEPQVLAPWDPMGALAQC"
     gene            complement(34503..35327)
                     /gene="nadE"
                     /locus_tag="VB649_000302"
     CDS             complement(34503..35327)
                     /gene="nadE"
                     /locus_tag="VB649_000302"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEP1669285.1"
                     /translation="MTLQEEIIRQLGVKASIDPQEEIRKAVDFLKAYLRKHSFLKTYV
                     LGISGGQDSTLAGKLAQMAIAELREETGNQAYQFIAVRLPYGVQVDEADAQKALAFIM
                     PDQTLTINIKAAVDGQVAALQEAGIEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
                     DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQK
                     PGLADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK"
     gene            complement(35329..36783)
                     /locus_tag="VB649_000303"
     CDS             complement(35329..36783)
                     /locus_tag="VB649_000303"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEP1669286.1"
                     /translation="MYKDDSLTLHTDLYQINMMQVYFEQGIHNRHAVFEVYFRKEPFN
                     NGYAVFAGLQRMVEYLEQFQFSETDLAYLEELGYPENFLTYLKELRLELTIRSAKEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQELDAAIWGTRAAIIGGADATSNVRAGKRFGIPVSGTHAHALVQAYGNDYDAFMAYA
                     KTHKDCVFLVDTYDTLKVGVPTAIRVAKEMGDKINFLGVRLDSGDLAYLSKTVRQQLD
                     DAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QEDGSMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTDINVNELTEIEM
                     FHPTYTYIKKTVKEFDAIPLLVDIFVKGELVYQLPTLAEIKAYAKKEFDKLWDEYKRV
                     LNPQDYPVDLARDVWQNKMALIDNIRKDAYGKSE"
     gene            complement(36954..38333)
                     /locus_tag="VB649_000304"
     CDS             complement(36954..38333)
                     /locus_tag="VB649_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEP1669287.1"
                     /translation="MSIKEQTDNNELENGMVRGLENRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGAFMFMMMRAIGEMLYYDPDQHTFINFISKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVGAYVQFWFPSWPAWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKILAILALIATAIFMVLTGFETHTGHASLSNIFDHFSMFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPTRIVIFYVGALVSIMAIVPWHQLPVDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTNRLK
                     INTLSRQGVPSRAIIASAVVVGISALINILPGVADAFSLITASSSGVYIAIYALTMIA
                     HWKYRQSKDFMADGYLMPKYKVTTPLTLAFFAFVFISLFLQESTYIGAIGATIWIIVF
                     GIYSNVKFK"
     gene            complement(38502..39419)
                     /gene="trxB"
                     /locus_tag="VB649_000305"
     CDS             complement(38502..39419)
                     /gene="trxB"
                     /locus_tag="VB649_000305"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEP1669288.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFD
                     IENYPGYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKT
                     VIIATGAKYRVLGVPGEEYYTSRGVSYCAVCDGAFFRGQDLLVVGGGDSAVEEAIYLT
                     QFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWDSVVKEIKGNDIKVSNVLIENVK
                     TGQVTDHAFGGVFIYVGMNPVTGMVKNLEITDSEGWIITDDHMRTSIPGIFAIGDVRQ
                     KDLRQITTAVGDGAIAGQGVYHYLESFPS"
     gene            complement(39483..39707)
                     /locus_tag="VB649_000306"
     CDS             complement(39483..39707)
                     /locus_tag="VB649_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEP1669289.1"
                     /translation="MLVEIFSLYVKGLILSSLTMMLICLIWTLWRAKTKRDKTLIERQ
                     AFLYEMLMVAILTIPILSFAFMSILVVIKS"
     gene            complement(39811..40554)
                     /locus_tag="VB649_000307"
     CDS             complement(39811..40554)
                     /locus_tag="VB649_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP1669290.1"
                     /translation="MITIRNLSKTFSGQKVLDSLALDIEKGQVIALVGASGAGKSTFL
                     RSLNYLEKPDSGSISIGDFTVDFETITTEQVLILRRKLAMVFQQFNLFERRTALENVK
                     EGLKVVKKLSDQEATKLAQAELAKVGLADRKHHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSITDAAKSGQTMVLVSHDMNFVYQVADRVLFLDQGKIL
                     EQGTPEEVFRHPQKERTKEFFASYSKTYI"
     gene            complement(40554..41357)
                     /locus_tag="VB649_000308"
     CDS             complement(40554..41357)
                     /locus_tag="VB649_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP1669291.1"
                     /translation="MTSVFLTSGWAFYDYLISPIPHGKLFSWHAVFDAIPNIIQRLPI
                     TLGLTLSGATFGLVLALIFALVKINKVKLLYPIQAIFVSFLRGTPILVQLMLTYYGIP
                     LFLKFLNQKYGFDWNVNAIPASIFAITAFAFNEAAYASETIRAAILSVDTGEIEAAKS
                     LGMTSVQVYRRVIIPNATVVAIPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGSD
                     YRYFERYISVALVYWSISILMEQVGRLIENKMAIKAPEQARNEKLGELR"
     gene            complement(41552..42895)
                     /locus_tag="VB649_000309"
     CDS             complement(41552..42895)
                     /locus_tag="VB649_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP1669292.1"
                     /translation="MSFKDYHFKQYIQQALEEIGFVNPTEVQKRLIPIVNSGRDLVGE
                     SKTGSGKTHTFLLPIFEKLDEAKAEVQVVITAPSRELATQIFDACKQIAKHFQEEIRL
                     ANYVGGTDKLRQIEKLKGSQPHIVIGTPGRIYDLVKSGDLAIHKATTFVVDEADMTMD
                     MGFLDTVDKIAASLPKSVQILVFSATIPQKLQPFLKKYLTNPVIEQIKTKTVIADTID
                     NWLVSTKGRDKNGQLLEILKTMQPYMAMLFVNTKERADDLHAFLTANGLKVAKIHGGI
                     PPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGMAGTAITLYQPSDDSDIKELEKMGIAFTPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKERRAENRAKGRAERKAKKQHF"
     gene            complement(43053..44063)
                     /locus_tag="VB649_000310"
     CDS             complement(43053..44063)
                     /locus_tag="VB649_000310"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEP1669293.1"
                     /translation="MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFL
                     KIFKQINEGLTAKQKLALQLVGGLMFYFLHVSPSGISSINVFGYQLPLGIFYLFFVLF
                     WVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQSQFDVLLLIGAMIGALLGFFC
                     FNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILY
                     VF"
     gene            complement(44065..46320)
                     /locus_tag="VB649_000311"
     CDS             complement(44065..46320)
                     /locus_tag="VB649_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP1669294.1"
                     /translation="MKKWQKYVLDYVVRDRRTPVENRVRVGQNMMLLTIFIFFIFIIN
                     FMIIIGTDQKFGVSLSEGAKKVYQETVTIQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSASDEKLYVQPSQYETVADILKKHLGMKKTDVIKQLKRKGLFQVSFGPSGSGIS
                     YSTMSTIQKAMEDAKIKGIAFTTSPGRMYPNGTFASEFIGLASLTEDKKTGVKSLVGK
                     TGLEASFDKILSGQDGVITYQKDRNGTTLLGTGKTVKKAIDGKDIYTTLSEPIQTFLE
                     TQMDVFQAKSNGQLASATLVNAKTGEILATTQRPTYNADTLKGLENTNYKWYSALHQG
                     NFEPGSTMKVMTLAAAIDDKVFNPNETFSNANGLTIADATIQDWSINEGISTGQYMNY
                     AQGFAFSSNVGMTKLEQKMGNAKWMNYLTKFRFGFPTRFGLKDEDAGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNNGEMLEPQFISQIYDPNTASFRTANKEIVGKPVS
                     KKAASETRQYMIGVGTDPEFGTLYSKTFGPIIKVGDLPVAVKSGTAQIGSEDGSGYQD
                     GGLTNYVYSVVAMVPADKPDFLMYVTMTKPQHFGPLFWQDVVNPVLEEAYLMQDTLTK
                     PVVSDANRQTTYKLPNFVGKNPGETSSELRRNLVQPVVLGTGSKIKKVSHQPGQTLTE
                     NQQVLILSDRFVEVPDMYGWTKSNVKTFAKWTGIDISFKGTDSGRVMKQSVDVGKSLK
                     KIKKMTITLGD"
     gene            complement(46324..46647)
                     /gene="ftsL"
                     /locus_tag="VB649_000312"
     CDS             complement(46324..46647)
                     /gene="ftsL"
                     /locus_tag="VB649_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEP1669295.1"
                     /translation="MTNEKRTQAVTNALQKRIKTFSRIEKAFYTAIIVTAITMAVSII
                     YLQSRKLQLQQEITSLNSHISDQKLELNNAKQEVNELSRRDRIIDIAGKAGLSNRNNN
                     IKKVE"
     gene            complement(46652..47665)
                     /gene="rsmH"
                     /locus_tag="VB649_000313"
     CDS             complement(46652..47665)
                     /gene="rsmH"
                     /locus_tag="VB649_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEP1669296.1"
                     /translation="MKSFSLTFSFLNLLKYGTIKVMTKEFHHVTVLLHETVDMLDIKP
                     DGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIK
                     DNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLT
                     AYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPA
                     KELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLT
                     KQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKK
                     IRK"
     gene            complement(47896..48111)
                     /locus_tag="VB649_000314"
     CDS             complement(47896..48111)
                     /locus_tag="VB649_000314"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669297.1"
                     /translation="MTNEREKEEAKVALEELLHQIQVIHLELKIVRNWGYFVFLEMVC
                     LSAGSNVVSKVNQLLIDLQVTLQNCRR"
     gene            complement(48131..49381)
                     /locus_tag="VB649_000315"
     CDS             complement(48131..49381)
                     /locus_tag="VB649_000315"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEP1669298.1"
                     /translation="MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTL
                     LAANQKDLANAKEHGISDIMMDRLRLTSERIKAMAQGVQQVADLADPIGQVIKGYTNL
                     DGLKILQKRVPLGVIAMIFESRPNVAVDAFSLAFKTNNAIILRGGKDAFHSNKALVKL
                     IRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVP
                     VIETGVGNVHIYVDAQADLDMATKIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLE
                     KAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSTLEEAISWINQ
                     HTSHHSEAIITRNIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHA
                     RGPMGLEALTSTKFYINGDGHIRE"
     gene            complement(49374..50195)
                     /gene="proB"
                     /locus_tag="VB649_000316"
     CDS             complement(49374..50195)
                     /gene="proB"
                     /locus_tag="VB649_000316"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEP1669299.1"
                     /translation="MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLM
                     NKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTN
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHATKFGDNDR
                     LSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVANITQEIIASAGGAGSKF
                     GTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVTHD"
     gene            complement(50260..51888)
                     /locus_tag="VB649_000317"
     CDS             complement(50260..51888)
                     /locus_tag="VB649_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669300.1"
                     /translation="MNWSTIWELIKINILYSNPQSLANLKKRQEKHPKENFKAYKSMM
                     RQQALMIAMFLVIYLFMFIGVDFSHYPGLFSFDVAMFFIMSTLTAFSSLYTIFYESND
                     LKLYIHLPVTSEELYIAKIVSSLGMGAVFLMPLISLLLIAYWQLLGNPLSILVAIVLF
                     LVLLVSSMVLAIYINAWVGKIIVRSRKRKLISTIMMFVSTFGAFVLIFAINISNNKRT
                     MMDGVFTDYPTIPYFKGFYDVVQAPFATAALLNFWLPLLLILAMVYGIVTKVMPTYYR
                     EAFYISNENKAKQTKKPVNRPHQNQSLAQLLRKHHLLTLQNATLLTQTYLMPLMYVML
                     FIGPSLSRGTGFFKHISPDYFGVALLFGVSLGIMCATPTSFIGVGISLEKDNFTFIKS
                     LPITLKKFLLDKFCLLVGLQLIVPMVIYLVFGLFVLHLHPLLTLAFCLGYALSLIVQG
                     ELMYRRDYRLLDLKWQDMTQLFTRGDGQWLTMGLIFGNLIVAGVLGFGAVIIANIIQQ
                     PLLISILLSCLILMVLGLAQLWIQKTFWKSLERL"
     gene            complement(51893..52627)
                     /locus_tag="VB649_000318"
     CDS             complement(51893..52627)
                     /locus_tag="VB649_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669301.1"
                     /translation="MIEFKHVSKLYGDKEALSDLNVTINDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYGEVFVDGQLLTENREAIKKQIAYVPDSPDIFLNLTPNEYWQFLAKIY
                     GVSDEDREERLAQLTTLFELKEEVNQTIDSFSHGMRQKVIVIGALVSNPNIWILDEPL
                     TGLDPQASFDLKEMMKAHAASGHTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTIDE
                     LKEHHPDKDLESIYLELAGRKAQEEG"
     gene            complement(52661..52927)
                     /locus_tag="VB649_000319"
     CDS             complement(52661..52927)
                     /locus_tag="VB649_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEP1669302.1"
                     /translation="MEKKRQRLYDVIRQAYDYPENRENVALSQLLLAASNRLIKHSNP
                     LLVAYQLNQDVDNYLLDNDILLPKSLCRFKQSLEKYILEEASSV"
     gene            complement(53120..55105)
                     /gene="tkt"
                     /locus_tag="VB649_000320"
     CDS             complement(53120..55105)
                     /gene="tkt"
                     /locus_tag="VB649_000320"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013793690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEP1669303.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDG
                     DLMEGVSQEAASMAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQKAF
                     TNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETD
                     FQPGHYEGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQN
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGILIATGSEVKLAMDT
                     QEALEAEGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGL
                     SGKTLTIDTWGASAPGNRIFEEYGFTVANATELYKSL"
     gene            complement(55323..55967)
                     /gene="fsa"
                     /locus_tag="VB649_000321"
     CDS             complement(55323..55967)
                     /gene="fsa"
                     /locus_tag="VB649_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEP1669304.1"
                     /translation="MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIK
                     EICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEI
                     IAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK"
     gene            complement(56093..57592)
                     /locus_tag="VB649_000322"
     CDS             complement(56093..57592)
                     /locus_tag="VB649_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP1669305.1"
                     /translation="MKIEDLMDKERRAQYRLLVTLYHAKETLRLKDLMRLSNLSKVTL
                     LKYIDNLNHLCREQGLACQLLLEKDSLSLKENGQFHWEDLVALLLKESVAYQILTYMY
                     CHEHFNITNLSVELMVSEATLNRQLAHLNQLLSEFDLALSQGRQLGSELQWRYFYFEL
                     FRHTLTRQGIDALVNQLDASHLATLIERLIGQSLSAEALEQLLIWLAISQARMSFQKG
                     YNDHFLRDSDFMTSNIFFKRLESMLLHYLRRYALEFDAFEAKSLFVFLHAYPLLPIAS
                     MKYSLGFGGPIADHISEALWLLKKAHVIIHQTKEEIIYGLGIFFSKAYFFKGAILSQP
                     TNSQYLYQLVGEDKRALLRVIINHLVLQMDQETDFSQQLSDDILALLIFSIERHHEPL
                     LVGLALGQNKVEAAIAELAIRRHLGHRRDFQLMPYDHQKVYDCLITYQTVCLPRQDLP
                     YYRLKQYSSPYELTALEAFLKDLFQQKNTREEELSLSPAAKSSFAHKTV"
     gene            complement(57582..58928)
                     /locus_tag="VB649_000323"
     CDS             complement(57582..58928)
                     /locus_tag="VB649_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP1669306.1"
                     /translation="MTLTTKTIHVIGASFAGLAFVDKYKDLNPDSQIILIDKESCPNY
                     IPNGINQLFRGDIQDLSDAMWGRACLAAQIESNHRFIQAEVLAIEAPSNTLLLKDSQG
                     RVFEEGYETLVCAMGASPQSHYIETSQTNKVLVTKYYEESQASLKLIEASQEVLVIGA
                     GLIGLDLAYSLSLQGKRVKLIEAAERPDFYQTDAELIAPVMAEMSTHHVTFINNKRVT
                     AIHEIEGKVVAHTEQGDTFQGDLAILAINFRPNTHLLQGQVACALDKTILVNENLQTS
                     QANIYAIGDMVSLHFGILGMDYYTPLINQAMKTGQALALHLAGYPIPPLQTVKVLGSS
                     HFGYYRASVGVTEEEAELYMDTCSYLYQNGDSKNLFWLKLIARKMDGILIGAQLLSKT
                     NALVIANQLGQALALKVTDGDLAFQDFLFLQGHSDLAYHLHEACLKLFEKRLRHED"
     gene            complement(59037..59738)
                     /locus_tag="VB649_000324"
     CDS             complement(59037..59738)
                     /locus_tag="VB649_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEP1669307.1"
                     /translation="MDIFGEFLGTALLVLLGNGVVAGVVLPKTKTHASGWIVIATGWG
                     IAVAVAVFISGKVAPAHLNPAVSFAFAMSGTIAWSTAIAYSLAQLLGAMVGSTLVFLQ
                     FRPHYLAAESQADILGTFATGPAIRDTSSNLLSEIFGTFVLMLGILAFGLYDMPAGLG
                     TLCVGTLVIGIGLSLGGTTGYAINPARDLGPRLVHAILPLNNKGDSDWSYAWIPVVGP
                     IIGAALAVLLFQVMS"
     gene            complement(59740..61578)
                     /gene="glpO"
                     /locus_tag="VB649_000325"
     CDS             complement(59740..61578)
                     /gene="glpO"
                     /locus_tag="VB649_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEP1669308.1"
                     /translation="MEFSRETRRLALQKMQERDLDLLIIGGGITGAGVALQAAASGLD
                     TGLIEMQDFAQGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEPGSTFSMFRLKVAMDLYDLLAGVSNTPAANKVLTKEEVLKREPDLKQEGL
                     LGGGVYLDFRNNDARLVIENIKRANHDGALIASHVKAEDFLLDDNGKIIGVKARDLLS
                     DQEIIIKAKLVINTTGPWSDEIRQFSHKGQPIHQMRPTKGVHLVVDRQKLPVSQPVYV
                     DTGLNDGRMVFVLPREEKTYFGTTDTDYTGDLEHPQVTQEDVDYLLGVVNNRFPNANV
                     TIDDIESSWAGLRPLLSGNSASDYNGGNSGKVSDDSFDHLVDTVKAYINHEDSREAVE
                     KAIKQVETSTSEKELDPSAVSRGSSFDRDENGLFTLAGGKITDYRKMAEGALTGIIQI
                     LKEEFGKSFKLINSKTYPVSGGEINPANVDSEIEAYAQLGTLSGLSMDDARYLANLYG
                     SNAPKVFALTRQLTAAEGLSLAETLSLHYAMDYEMALKPTDYFLRRTNHLLFMRDSLD
                     ALIDPVINEMAKHFEWSDQERVAQEDDLRRVIADNDLSALKGHQEG"
     gene            complement(61594..63120)
                     /gene="glpK"
                     /locus_tag="VB649_000326"
     CDS             complement(61594..63120)
                     /gene="glpK"
                     /locus_tag="VB649_000326"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEP1669309.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAG
                     WVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAI
                     VWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEV
                     KSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFA
                     LASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     AVGYWEDMDALKKLNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
                     "
     gene            complement(63480..63872)
                     /locus_tag="VB649_000327"
     CDS             complement(63480..63872)
                     /locus_tag="VB649_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEP1669310.1"
                     /translation="MCLSYNRRNQRKKVVLMTIKKFSLLAIASLSLLSLAACDMDDKD
                     DHMDNQPKTSQTSQKVKLSEDKAKSIALKDASVTEADAQMLSVTQDNEDGKAVYEIEF
                     QNKDQEYSYTIDANSGDIVEKSSEPIND"
     gene            complement(63999..64256)
                     /locus_tag="VB649_000328"
     CDS             complement(63999..64256)
                     /locus_tag="VB649_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEP1669311.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS"
     gene            complement(64410..66449)
                     /locus_tag="VB649_000329"
     CDS             complement(64410..66449)
                     /locus_tag="VB649_000329"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEP1669312.1"
                     /translation="MSKNLLIELGLEELPAYVVTPSEKQLGERLATFLTENRLSFEDI
                     QTFSTPRRLAVRVSGLADQQTDLTEDFKGPAKKIALDADGNFSKAAQGFVRGKGLTTD
                     AIEFREVKGEEYVYVTKHEAGKPAKEVLLGVTEVLSAMTFPISMHWANNSFEYIRPVH
                     TLTVLLNDEALELDFLDIHSGRVSRGHRFLGTETTITSADSYEADLRSQFVIADAKER
                     QEMIVEQIKTLEVEQGVQVDIDEDLLNEVLNLVEFPTAFMGSFEAKYLDVPEEVLVTS
                     MKNHQRYFVVRDQAGHLMPNFVSVRNGNDQAIENVIKGNEKVLVARLEDGEFFWREDQ
                     KLQIADLVAKLTNVTFHEKIGSLAEHMDRTRVIAASLAKEANLSAEEVTAVDRAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEDAAVATAIREHYLPDAAGGALPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILDHFGWRIPMDKLVDSLYD
                     LSFDSLTYANKADVMNFIRARVDKMMGKAAPKDIREAILASSTFVVPEMLAAAEALVK
                     ASHTENYKPAVESLSRAFNLAEKADASVQVDPSLFENEQENTLFAAIQGLTLAGSAAQ
                     QLEQVFVLSPVINDFFDNTMVMAEDQALKNNRLAILSDLVSKAKTIAAFNQLNTK"
     gene            complement(66826..67743)
                     /gene="glyQ"
                     /locus_tag="VB649_000330"
     CDS             complement(66826..67743)
                     /gene="glyQ"
                     /locus_tag="VB649_000330"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEP1669313.1"
                     /translation="MSKKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLASLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEISDQDMLLENFE
                     KFEKEASRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAILLAEDGE"
     gene            complement(68115..68648)
                     /locus_tag="VB649_000331"
     CDS             complement(68115..68648)
                     /locus_tag="VB649_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEP1669314.1"
                     /translation="MTIFLVMLAMFTIRLVFLKKSITNEKAILAQGGQEFGAQNTKFL
                     TLLHIMIYVFAVIEALLKQIKFDGISFLGLLLMLLSVAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTIKHPNYFLNIAPELVGIALLCHAKITAMLLFPCYIVVIYLRIREE
                     NKLLAEVIIPNGTRTKP"
     gene            complement(68780..69619)
                     /locus_tag="VB649_000332"
     CDS             complement(68780..69619)
                     /locus_tag="VB649_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEP1669315.1"
                     /translation="MVTTVKMTSGYEIPVLGFGTYQAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYKNEESVGRAIKDSGVLREDLFITTKLWNDAHSYEGAKDALAASLDRLGLDYV
                     DLYLIHWPNPKALRNTWKEANAQAWQYMEEAVEAGLIKSIGVSNFMVHHLEALQETAK
                     ITPAINQIRLAPGCYQKEVVDYCKANEILLEAWSPLGQGEIFDNETMQQLANKYDKTV
                     AQVALAWSLAEGFIPLPKSVHDERIKENMAIFDVSLTQEDKKTIRYLSGMSAIPNPDN
                     TSF"
     gene            complement(69741..70889)
                     /gene="nagA"
                     /locus_tag="VB649_000333"
     CDS             complement(69741..70889)
                     /gene="nagA"
                     /locus_tag="VB649_000333"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEP1669316.1"
                     /translation="MTCYLKADCFYYPTEVKPAGYLGLHDGVFGEWTEIVPADAQIID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAQGIHQMSEGLLATGVTSFLPTTLTSTFEQL
                     EKVSGTIASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPSYMKTPRLEEFDAWQKAAK
                     GLIKKIALAPERDGVKEFVSAVTKQGVTVALGHSNGTYQEAKEAVQAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNLPNTYAELICDGHHVSPVACDILMQQKGHDHVAMITDCMRA
                     GGSPDGDYLLGEFSVVVANGTARLKESGNLAGSILKLKDGLRNVVTWGIATPAEAIHM
                     ATYVPAVSVGIDDVCGQIKAGHAADFIVLDKDLTLVATYLNGQKAFDA"
     gene            complement(71007..72638)
                     /locus_tag="VB649_000334"
     CDS             complement(71007..72638)
                     /locus_tag="VB649_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEP1669317.1"
                     /translation="MSVNWQDIAFHFFGGLGLFLFSIKYMGDGLQQAAGDKLRYYIDK
                     YTSNPFFGILVGIAMSALIQSSSGVTVITVGLVSAGLLNLRQAIGIVMGANIGTTITS
                     FLIGFKLGDYALPMIFIGAACLFFTSNKKLNNFGRIIFGVGGIFFSLNLMGDAMDPLK
                     SVSAFQNYLATLGDKPFQGVFIGTALTMLIQSSAAIIGILQGLFSGGLLTLQGAIPIL
                     LGSNIGTCITAVLAAIGSNIAAKRVAAAHVLFNLIGTIIFMIILVPFTSLMLWLQSKL
                     SLTPEMTIAFSHGSFNITNTILLIPFISLLAMIVTRLIPGEDEVVKYEALYLDRLLIT
                     QAPSIALGNAHKELVHLASYAIQAFEASYSYIMTADDKLGEKVKRYERAVDTIDEELT
                     TYLVDISNEALSPSENEVLAGILDSSRDLERIGDHSESLGILIEGIISKQIGFSISAR
                     QELTEMYQLTHCLTLDAIRAIVDSDTDLAQTIVTRHKEIEEKERRLRKTHIKRLNCGE
                     CTAQAGINFIDIISHYTRITDHALNLAEKVLSHQL"
     gene            72840..73562
                     /locus_tag="VB649_000335"
     CDS             72840..73562
                     /locus_tag="VB649_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669318.1"
                     /translation="MATMKQYHKGDSMTKSQKEALYWMLSVLTITLIGGSCLIFGSHP
                     QTQDKVAKHSKSAASLLKKAVKAVNDADRLATAAAIQEAQKAVDKLAESSKKKTLQEQ
                     LNVAKAKQEQEDAATQAVKAAEETLNQNLKDIAQKAVNDLSNKGKKAALQSRLDAILP
                     AKPIIDEFPRQSGEITDNSYWTPFPGDVSDTYDNSQSPTLDPSSESSASDVTPQPSHP
                     DPIPPQTSSEPSDSGDKQSSKE"
     gene            complement(73691..74533)
                     /locus_tag="VB649_000336"
     CDS             complement(73691..74533)
                     /locus_tag="VB649_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP1669319.1"
                     /translation="MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDG
                     LDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKN
                     ELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIF
                     VLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEE
                     IQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLM
                     GYEI"
     gene            74826..75383
                     /locus_tag="VB649_000337"
     CDS             74826..75383
                     /locus_tag="VB649_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP1669320.1"
                     /translation="MTDKALSKRSLQNLTQFNKETRRIARESMEIALLNLLETKPLGD
                     ITISELVTKAGVSRNAFYRNYTSKEAIIEQLLVGVIRRIFRGLKQFDIKTQAYQAWLY
                     LFTEAKKEAQLLKMIFKHHLHHLLTRLVTKRLKAYQKLKDKKQSHYKRLFWSNAIVSV
                     LTNWISDDMIVPAEEMAAMGLPLLT"
     gene            complement(75419..76243)
                     /locus_tag="VB649_000338"
     CDS             complement(75419..76243)
                     /locus_tag="VB649_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP1669321.1"
                     /translation="MIQLIAIDLDGTLLNQDKQIPKENITAIQEAAQSGLKIVLCTGR
                     PQSGTRPYFDQLGLTQEEFLIINNGCSTYSSPDWQLRHSKMLKVSDIELLEELSQSFP
                     DIYLTLTEENDYLVLEEEVPDLVQEDGDLVFTIVKPVSLAELSDTPRLIFQAMYLGEK
                     AALDAFERAVRNQLSQSFHVVRSQDNILEILPQGVSKASALKELVEDLGLTADQVMAI
                     GDAPNDIEMLTYAGLGVAMENASAAIKPLADKVTLTNDMAGVAQAIRQFALAAQKD"
     gene            complement(76245..76862)
                     /locus_tag="VB649_000339"
     CDS             complement(76245..76862)
                     /locus_tag="VB649_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEP1669322.1"
                     /translation="MTIDMWEILNIIGTIAFALSGAIVAMEEEFDILGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQKPEFTCAFFAMVLIMLFPKLIARGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLNQPLSAVIVAAVLTGAGGGVVRDILAGRKPSVLRSEIYAGWSILA
                     AIVLHFKLADSTIECYALVVLLTTLRMIGNRKKWNLPKIKWKEER"
     gene            complement(77059..78036)
                     /gene="lacD"
                     /locus_tag="VB649_000340"
     CDS             complement(77059..78036)
                     /gene="lacD"
                     /locus_tag="VB649_000340"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEP1669323.1"
                     /translation="MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEAT
                     VTQIETLKVLVSEELTPYASSILLDPEYGLLATKVRANQTGLLLAYEKTGYDATTTSR
                     LPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFF
                     LELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFT
                     EGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCG
                     RATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI"
     gene            complement(78083..78536)
                     /locus_tag="VB649_000341"
                     /pseudo
     CDS             complement(78083..78536)
                     /locus_tag="VB649_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP;
                     frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            complement(78546..79061)
                     /gene="lacB"
                     /locus_tag="VB649_000342"
     CDS             complement(78546..79061)
                     /gene="lacB"
                     /locus_tag="VB649_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEP1669324.1"
                     /translation="MKIAIGCDHIVTNEKMAVSDFLKSKGYDVIDCGTYDHTRTHYPI
                     FGKKVGEAVVNGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIDAFIKAEYKETEENKKLIAKIAHLESHHANQEDPDFFTEF
                     LEKWDRGEYHD"
     gene            complement(79076..79501)
                     /gene="lacA"
                     /locus_tag="VB649_000343"
     CDS             complement(79076..79501)
                     /gene="lacA"
                     /locus_tag="VB649_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEP1669325.1"
                     /translation="MAIILGADAHGNALKELIKSFLQEEGYDIIDVTDINSDFIDNTL
                     AVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMIT
                     IGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA"
     gene            complement(79758..81209)
                     /locus_tag="VB649_000344"
     CDS             complement(79758..81209)
                     /locus_tag="VB649_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEP1669326.1"
                     /translation="MMQPFLDIINKILGFPIQLGSGVVMLIVMTGLAMIFGVKFTKAL
                     EGGIKLAIALTGIGAIIGILTGAFSESLQAFVKNTGISLNIIDVGWAPLATITWGSPY
                     TLYFLLVMLVVNIVMIVMKKTDTLDVDIFDIWHLSITGLLIMWYADHNHLPVLVSLLI
                     ATVAVILVGVLKIINSDLMKPTFDDLLGTGSQSPMTSTHMNYMMNPIIMVLDKIFDKV
                     FPGLDKYDFDAAKLNKKIGFWGSKFFIGMALGFVIGIMGDPHFTVESIKNWFGLGFTA
                     GACLELFSLIGSWFIAAVEPLSQGITNFANARMHGRRFNIGLDWPFIAGRAEIWACAN
                     ILAPIMLIEAVLLSKVGNGILPLAGIIAMGMTPALLVVTRGRLIRMIIFGSLLLPLFL
                     LSGTMIAPFATELAKKVGAFPAGTSAGSLITHSTLEGPMEKIFGYVIGQATTGQIASI
                     ITLIIFVAIYLGLFAWYANQMKARNAEYAKTMK"
     gene            complement(81238..81540)
                     /locus_tag="VB649_000345"
     CDS             complement(81238..81540)
                     /locus_tag="VB649_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP1669327.1"
                     /translation="MIKILAACGAGVNSSHQIKDAIETQMSDRGYDVHCDAVMVKDIT
                     EELVSRYDIFTPIAKTDLGFEMPIPTVEAGPILYRIPIMSEPVFAELERVIKENHL"
     gene            complement(81533..82006)
                     /locus_tag="VB649_000346"
     CDS             complement(81533..82006)
                     /locus_tag="VB649_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP1669328.1"
                     /translation="MFPNILFTEARTQPELFDLVASYLEKVGYVTQEYHQALVEREAV
                     FPTGLKVDLKDGSDILYAAIPHTETKYCLVDQVVYVRNSQALTFKHMINPEEDCLVTD
                     FFFIINSQNEGQTTILSNLITFFITKGNLSYLASLKDDKQAISNYLIEKGVFQHD"
     gene            82243..83013
                     /locus_tag="VB649_000347"
     CDS             82243..83013
                     /locus_tag="VB649_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP1669329.1"
                     /translation="MLKRERLLKITEIVNEQGIVTVNDIIQTLNVSDMTVRRDLDELE
                     KAGKLIRIHGGAQSITMPNKKERSNIEKQTVQTKEKWELASYATQLVNDGETIFIGPG
                     TTLECFAEQLKNRQIRIVTNSLPVFNILQDSETIDLILIGGEYRSITGAFVGSLASQN
                     ISSLKFAKAFISCNGIYKNDIATYSETEGEIQKLAFNNSIEKYLLVDNQKFNAYDFFI
                     FYHLNNIDAVVTDSQITEDVIERYSQFTQLLVAHENKK"
     gene            complement(83217..83420)
                     /locus_tag="VB649_000348"
     CDS             complement(83217..83420)
                     /locus_tag="VB649_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HEP1669330.1"
                     /translation="MEKHYQVTGMTCDGCARTVTEKLSAVPGVQSVQVNLEKGEAKVT
                     GRPLTFLLKRALKDTKFELHKWS"
     gene            complement(83434..85665)
                     /locus_tag="VB649_000349"
     CDS             complement(83434..85665)
                     /locus_tag="VB649_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEP1669331.1"
                     /translation="MAKEIFLVEGMSCASCALTIEKTVNQLPEVEQAVVNLATEKLTV
                     TYQDDDLETAKVIQAVKAAGYGAQVFDEHAKHMQTGRRDEDLKVIWSQVLWSALFTIP
                     ILYLAMGHMVGLWLPPFLQPDRYPFVYSFSQLLLTIPVLVLNRHYYHNGFKALFKGHP
                     NMDSLVALATSFAFAYSLYGVVEISLGRAHFVHSLYFESVVVILTLIGLGKYFESRSK
                     GRTSQAIQKLLSLKATDVRVWRNSQWQLLPLEEVSYDDLVLVQPGEKVSIDGIIVEGH
                     SSLDESFLTGESLPVEKGEKDNVFAGSLNGQGALTIKPDKLGNDTLLAQIIQLVENAQ
                     ENKAPIATIADRVSGVFVPVVLVLALLTGVFWLVFMQESLRFSLTTAIAVLVIACPCA
                     LGLATPTAIMVGTGRAAENGILFKGGDILEQAHQVDTVVFDKTGTITEGKPSLQKLLI
                     FSGDDHLILQEAASLEAYSQHPLGEAIVRAAQEAGYDSLPVEEFESLTGLGVTGQLEG
                     RRLAIGNATLMATLGIDLSCVQSVCAKASGKGQTLVYYAKEGQLRALFSIADAVKEDS
                     QATVEALHQLGIHTIMLTGDHDATAKAIASQVGITDVISQVLPDQKAGVIADLRSQGR
                     KVAMVGDGINDAPALAVADIGIAMGSGTDIAIESADVILMKPDMLDLVKAMSLSRATM
                     RIVKENLFWAFIYNVLMIPVAMGLLHLFGGPLLNPMLAGFAMSFSSVSVVLNALRLKG
                     KTI"
     gene            complement(85665..86099)
                     /locus_tag="VB649_000350"
     CDS             complement(85665..86099)
                     /locus_tag="VB649_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEP1669332.1"
                     /translation="MQQISAAEWEVMRVVWASGDIKSSDIITILRKKYQWSDSTIKTL
                     IGRLVKKNLLTSYRQGRAYIYQALLDETLLQKEALATVLDGICQRQHTRLLLERLYHL
                     PMTLEEIGAFQELLEVKKENAVLEVPCNCLPGQCHCQRKETY"
     gene            86271..87257
                     /locus_tag="VB649_000351"
     CDS             86271..87257
                     /locus_tag="VB649_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP1669333.1"
                     /translation="MKHPIRKTLVALGLLLTLCLPTPVAASSRSWKSWFIEQYFWLKR
                     DKSYYSKQDDPSFQRYLDACREQSDKPYQLDTNLVNGPLVQENLYGMQVYSWNDNGKP
                     DQKTIIYLAGGSYLNNPTTYHINMLKTLSTSLDAKIVLPIYPKAPRYTYNYTMPKLVN
                     LYQHYYHKNQNVFLMGDSAGGGLALGLAHALHNESVPQPKQLVLLSPWLDVTMSHPEI
                     PEYEDADPILSSWGLKRVGELWAYSADNTNHIYVSPKNGPITYLPPITLFTGTREIFY
                     PDIRDYAAKLKAANHNITFITQEGMNHVYPIYPIEEAKTAQYQIIDAINKTP"
     gene            complement(87391..87741)
                     /gene="rbfA"
                     /locus_tag="VB649_000352"
     CDS             complement(87391..87741)
                     /gene="rbfA"
                     /locus_tag="VB649_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEP1669334.1"
                     /translation="MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDL
                     SLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRDLDNKS"
     gene            complement(87947..90808)
                     /gene="infB"
                     /locus_tag="VB649_000353"
     CDS             complement(87947..90808)
                     /gene="infB"
                     /locus_tag="VB649_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEP1669335.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAK
                     KIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAER
                     EARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIER
                     KASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAA
                     LKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEE
                     AETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKN
                     SNWNKNKKTKKGKNVKNTNTVPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAE
                     IVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPE
                     NIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFL
                     DTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKID
                     KPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKA
                     DPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRV
                     KSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLD
                     NLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDV
                     TLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQ
                     EKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYK
                     DDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK"
     gene            complement(90828..91130)
                     /locus_tag="VB649_000354"
     CDS             complement(90828..91130)
                     /locus_tag="VB649_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEP1669336.1"
                     /translation="MTNLERLSSLIGLAQRAGKVISGEELVVKAIQHQQVILVFLAND
                     AGPNVTKKVTDKSNYYNVEVSTVLNALELSAALGKPRKVAAIADAGFSKKMRTLME"
     gene            complement(91123..91419)
                     /locus_tag="VB649_000355"
     CDS             complement(91123..91419)
                     /locus_tag="VB649_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEP1669337.1"
                     /translation="MSKVKKIPLRKSLVSGEIIAKRDLLRIVKTKDGQVFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMDIPESFYDDLIAYVDHKIKRRELGLD"
     gene            complement(91435..92592)
                     /gene="nusA"
                     /locus_tag="VB649_000356"
     CDS             complement(91435..92592)
                     /gene="nusA"
                     /locus_tag="VB649_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEP1669338.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIDAVTESLKSAYKRRYGQSES
                     CVIEFNEKTADFQVFTVREVVEEVFDSRLEISLKDALAISSAYELGDKIRFEESVNEF
                     GRVAAQSAKQTIMEKMRRQMREVMFNEYKEHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRVDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDEDLKRATVVVPDSKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYDRLEAEKEAATAVEEPVVDDVMTAEEV"
     gene            complement(92767..93303)
                     /gene="rimP"
                     /locus_tag="VB649_000357"
     CDS             complement(92767..93303)
                     /gene="rimP"
                     /locus_tag="VB649_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEP1669339.1"
                     /translation="MDSQGPIILEKSIKIEEVIKIANTSIIDIVTKTVTPEIKAPYEL
                     VDVEYDKMGSDYILSILVDKEGGITVEDTSDLTNIISPLLDTIDPDPFPNQYMLEVSS
                     PGLERPLKTADSLKAAVGSYINVSLYQAIDKVKVFQGDLLAFDGETLTIDYLDKTRHK
                     IVNIPYQAVAKVRMAVKL"
     gene            complement(93411..93497)
                     /locus_tag="VB649_000358"
     tRNA            complement(93411..93497)
                     /locus_tag="VB649_000358"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(93461..93463),aa:Ser,seq:gga)
     gene            complement(93562..94197)
                     /gene="trmB"
                     /locus_tag="VB649_000359"
     CDS             complement(93562..94197)
                     /gene="trmB"
                     /locus_tag="VB649_000359"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEP1669340.1"
                     /translation="MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIE
                     VGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTN
                     YFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFE
                     YSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF"
     gene            complement(94197..94988)
                     /locus_tag="VB649_000360"
     CDS             complement(94197..94988)
                     /locus_tag="VB649_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEP1669341.1"
                     /translation="MTTTEQELTLTPLRGKSGKAYKGTYPNGECVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTKEDMNSKQIIHILLRLHKSKKLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFKSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDSVRLTDRMYDVAYLLSHYIPRSRWSEWLSYYGYKNNDKV
                     MQKIIWYGQFSHLTQILKCFDKRDMEHVNQEIYALRKFREIFRKK"
     gene            complement(95052..96086)
                     /locus_tag="VB649_000361"
     CDS             complement(95052..96086)
                     /locus_tag="VB649_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669342.1"
                     /translation="MKALFLKRRQDFQKQQNKYLRYVLNDHFVLVLMFLLGFAMVQYG
                     QLLNHFPTNHLPIQVCLGILIPLLLSMGSIATYLEEADQHFLLPKEEEVISYIKQAER
                     LSFLLWGTLQTAVLLFLYPIFRRLGLSLFIFIILVLILLALKRVVLSRKTRYFLRGNR
                     LDWAKAVAFESNRKQSILKFYSLFTTVKGISTKVKERTYLNPLLKLVKQTPSNLWLSL
                     YARAFLRSSDYLGLFLRLMLLSSLSVFFIHNLYLSVSLALIFNYLVVFQLLSLYYHYD
                     YHYMTSLYPENSRSKKKNMLSFLRGLSFLMLIVNMLCCSSAPKALMLIVGMVFIACIY
                     LPYKLKKIID"
     gene            complement(96089..96814)
                     /locus_tag="VB649_000362"
     CDS             complement(96089..96814)
                     /locus_tag="VB649_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669343.1"
                     /translation="MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIPETPSLYEELTLSEHINTVAMAY
                     DIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLAD
                     LQEAFGDRSASLNDIYLALTKED"
     gene            96886..97305
                     /locus_tag="VB649_000363"
     CDS             96886..97305
                     /locus_tag="VB649_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEP1669344.1"
                     /translation="MENCIFCSIIQGDIPSSKVYEDEQVLAFLDISQTTKGHTLVIPK
                     QHVRNLLEMTAETASHLFARIPKIARAIQSATGATAMNIINNNEALAGQTVFHAHVHL
                     VPRYNEEDGISIQYTTHEPDFPVLEKLARQINQEVSS"
     gene            97302..97658
                     /locus_tag="VB649_000364"
     CDS             97302..97658
                     /locus_tag="VB649_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEP1669345.1"
                     /translation="MKVKTVIAVGLLSFTAYKAYQKRCTIKELLSISRQAKDAAQLDL
                     DNIKANLDLIHSQGKVIQNISQDLAHKWRYFNQETQAHLTEIQNRMAKYQEDSELISS
                     ESPTCQTVILTNNHSR"
     gene            complement(97769..99043)
                     /locus_tag="VB649_000365"
     CDS             complement(97769..99043)
                     /locus_tag="VB649_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEP1669346.1"
                     /translation="MKIGKKIVLMFTAIVLTTVLALGVYLTSAYTFSTVELSKTFKDF
                     STSSKKSDAIKQTRAFSILLMGVDTGSSERASKWEGNSDSMILVTVNPKTKKTTMTSL
                     ERDTLTTLSGPKNNEMNGVEAKLNAAYAAGGAQMAIMTVQDLLNITIDNYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIAENEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALDSISSYRKILSAVSSNMQTNIEISSRTIPSLLGYRD
                     ALRTIKTYQLKGEDATLSDGGSYQIVTSNHLLEIQNRIRTELGLHKVSQLKTNATVYE
                     NLYGSTKSQTVNNNYDSSGQAPSYSDSHSSYANYSSGVDTGQSASTDQDSTASSHTPA
                     TPSSSSDALAADESSSSGSGSLVPPANINPQT"
     gene            complement(99052..99576)
                     /locus_tag="VB649_000366"
     CDS             complement(99052..99576)
                     /locus_tag="VB649_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP1669347.1"
                     /translation="MIQQSLVIEEGVPQDAKAVLSLVTAAAKETDFITGVETILEATP
                     QELSDFLSRSQTSFIDFCLLARLDEKVVGLLNLSGEVLSQGQAEADVFMLVAKTYRGY
                     GIGQLLLEIALDWAEENPYIESLKLDVQVRNTKAIYLYKKYGFRIESMRKNDIKSKNG
                     DDLDVYHMRKSVSQ"
     gene            complement(99551..100012)
                     /gene="tsaE"
                     /locus_tag="VB649_000367"
     CDS             complement(99551..100012)
                     /gene="tsaE"
                     /locus_tag="VB649_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEP1669348.1"
                     /translation="MFYSENEYTLKAYGATLGTYLSIGDVIVLSGDLGAGKTTLAKGI
                     AKGMGISQMIKSPTYTIVREYEGRLPLYHLDIYRVGDDPDSIDLDDFLFGNGVTVIEW
                     GELLGEGLLQDYLQITITKRDKGRQLDLLAHGERSRQLLEIMSHDSAKSRY"
     gene            complement(100166..101626)
                     /locus_tag="VB649_000368"
     CDS             complement(100166..101626)
                     /locus_tag="VB649_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEP1669349.1"
                     /translation="MEKFFKLSENGTTVSTEIMAGLTTFFAMSYILFVNPSILGAAGM
                     PSNAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFALGFSWQEALAM
                     VFICGLFNIFITVTKFRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANIITFSISAE
                     NIVMVNGVEPAKASAKTFADGLLFVDANGGVVPTISSFTDSSVLLAIFGLLLTTALVI
                     RNFRGAILIGIVATTLVGIPLGIVDVSNLNFGISHIGEAWTELGTTFLAAFDGLSSLF
                     SDSSRLPLVFMTIFAFSLSDTFDTIGTFIGTGRRTGIFSQDDENALENSIGFSSKMDR
                     ALFADAIGTSIGALVGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFLLSILLLPLVG
                     IVPAAATAPALIVVGVMMVSSFLDVNWSKFADALPAFFAAFFMALCYSISYGIAAAFI
                     FYCLVKVVEGKTKDIHPIIWGATFLFIVNFIILTIL"
     gene            101890..102702
                     /locus_tag="VB649_000369"
     CDS             101890..102702
                     /locus_tag="VB649_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEP1669350.1"
                     /translation="MTKKLIAIDLDGTLLHHDNTISTYTQKTIKAVQDKGHHVIISTG
                     RPYRMALGYYLQLNLKTPIITFNGALTHMPEQKWAYEHNVTLDKGYLLRLLQYQDDFQ
                     MDFIASEYRKNVYITMTNPESIDPQLFGVDEITQDMALEITKITRNPNALLMQTRHED
                     KYALAKNMRAFFKDEIEIDSWGGPLNILEISSKNINKAYALNYLLGIYNMDKKDLIAF
                     GDEHNDTEMLAFAGTGYAMKNASPVLLPYADQQLNFSNEEDGVAKKLEELFL"
     gene            103054..104046
                     /gene="manX"
                     /locus_tag="VB649_000370"
     CDS             103054..104046
                     /gene="manX"
                     /locus_tag="VB649_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEP1669351.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDAGAGVEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAG
                     TVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIIASDEVAQDDLRKQLIKQAA
                     PGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAH
                     STGKTMVNNVLSMDKEDVATFEKLRDLGVTFDVRKVPNDSKKNLFELIQKANIK"
     gene            104135..104944
                     /locus_tag="VB649_000371"
     CDS             104135..104944
                     /locus_tag="VB649_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEP1669352.1"
                     /translation="MSDISIISAILVVIIAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVILGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKSGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTLSTALVHAGDKAAAEGNFAGIERFHFIALLLQGLRIAVPA
                     ALLVAVPTSAVQSVLNAMPNWLNEGMQIGGAMVVAVGYAMVINMMATREVWPFFALGF
                     ALAAISQLTLIAMGVIGVAIAFIYLNLSKKGGNGGNAAGSADPIGDILEDY"
     gene            104961..105872
                     /locus_tag="VB649_000372"
     CDS             104961..105872
                     /locus_tag="VB649_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP1669353.1"
                     /translation="MTEQIKLTKSDRQRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTSPEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTPIDDKAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLASTGNIVGPLLFFFGWNLIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTIDLPGKQLSDGA
                     YVVFPDGAVKGAELKTILANAIGGMSLDKVQAQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIGLFAFGILAHLAGIM"
     gene            105986..106345
                     /locus_tag="VB649_000373"
     CDS             105986..106345
                     /locus_tag="VB649_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEP1669354.1"
                     /translation="MAQSLNTSVEYKTKAVSYLGMGGKVGHILLGDKALEFYNDKNVN
                     DYIQIPWTAINHIGANVSRKKVSRHFEIFTDQGKFLFASGDSGKILKITRQHIGNEKV
                     ITLPTLMQTFINKFFRH"
     gene            106737..108014
                     /gene="serS"
                     /locus_tag="VB649_000374"
     CDS             106737..108014
                     /gene="serS"
                     /locus_tag="VB649_000374"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEP1669355.1"
                     /translation="MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRALLVQ
                     SEKLKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIIT
                     VLPNTPHDSVPIGADEEDNVEIRRWGTPRDFNFEVKAHWDLGEDLDILDWECGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGETVISPK"
     gene            complement(108247..109017)
                     /locus_tag="VB649_000375"
     CDS             complement(108247..109017)
                     /locus_tag="VB649_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEP1669356.1"
                     /translation="MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGA
                     IVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVV
                     TFINTAGAYPGVGAEERGQGEAVAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYF
                     SSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY"
     gene            complement(109014..109880)
                     /locus_tag="VB649_000376"
     CDS             complement(109014..109880)
                     /locus_tag="VB649_000376"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEP1669357.1"
                     /translation="MALFRKKDKYIRITPNNSLKGSVSHNVPEVPDELFAKCPACKHM
                     IYKKDLGLAKICPTCSYNFRISAQERLTLTVDEGSFQELFISIETKDPLRFPGYQEKL
                     QKAKETTGLHEAVLTGKAMVKGQQIALAIMDSHFIMASMGTVVGEKITRLFELAIEEN
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAVKRHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDIILAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLQDHGFVDAIVKRTELRDK
                     IAHLVAFHGGGQ"
     gene            complement(109889..111253)
                     /locus_tag="VB649_000377"
     CDS             complement(109889..111253)
                     /locus_tag="VB649_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEP1669358.1"
                     /translation="MFKKILIANRGEIAVRIIRAARELGISTVAVYSEADKEALHTIL
                     ADEAICIGPARSKESYLNMNSVLSAAIVTGAQAIHPGFGFLSENSKFATMCEEMNIKF
                     IGPSASVMDKMGDKINARSEMIKAGVPVIPGSDGEVYNAQEALAIANKIGYPVMLKAS
                     AGGGGKGIRKVETEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDAY
                     GNIIHLGERDCSLQRNNQKVLEESPSIAIGNTLRHEMGQAAVRAAEAVAYENAGTIEF
                     LLDEDSEKFYFMEMNTRIQVEHPVTEFVTGVDIVKEQIKIAAGQPLAINQEDITITGH
                     AIECRINAENTAFNFAPSPGKITDLYMPSGGVGLRVDSAVYNGYAIPPYYDSMIAKII
                     VHGSNRFDALMKMQRALVELEIEGIITNTDFQLDLISDKRVIAGDYDTSFLMETFLPH
                     YNKD"
     gene            complement(111285..111707)
                     /gene="fabZ"
                     /locus_tag="VB649_000378"
     CDS             complement(111285..111707)
                     /gene="fabZ"
                     /locus_tag="VB649_000378"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEP1669359.1"
                     /translation="MMDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFF
                     NGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ"
     gene            complement(111704..112204)
                     /locus_tag="VB649_000379"
     CDS             complement(111704..112204)
                     /locus_tag="VB649_000379"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEP1669360.1"
                     /translation="MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTS
                     NQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAY
                     LAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
                     GLVRIK"
     gene            complement(112206..113438)
                     /gene="fabF"
                     /locus_tag="VB649_000380"
     CDS             complement(112206..113438)
                     /gene="fabF"
                     /locus_tag="VB649_000380"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEP1669361.1"
                     /translation="MTFKRVVVTGYGLTSPIGHDPETFWNNLKAGQIGIGPITKFDTT
                     DYAVKNAAEIQDFPFDKYFVKKDLNRFDRYSLYALYAAKEAINHADLNIEMIDSDRFG
                     VIVASGIGGIAEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMSLKAQGVCKSI
                     NTACASSNDAIGDAFRAIKFGTQDVMIVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQERGATILAEIVGYGNTCDAYHMTSPNPEG
                     LGARKAIHLALQEAGIEASAINYVNAHGTSTPANEKGESQAIVAVLGKDVPVSSTKSF
                     TGHLLGAAGAIEAIATIEAMRHNYVPMTAGTQALSEDIEANVIFGEGKETAINYAISN
                     TFGFGGHNAVLAFKCWEE"
     gene            complement(113453..114187)
                     /gene="fabG"
                     /locus_tag="VB649_000381"
     CDS             complement(113453..114187)
                     /gene="fabG"
                     /locus_tag="VB649_000381"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEP1669362.1"
                     /translation="MEIKGKNIFITGSTRGIGLAMAHQFASLGANIVLNGRSAISEEL
                     VASFTDYGVTVVTISGDVSEASEAKRMVNEAIESLGSIDVLVNNAGITNDKLMLKMTE
                     EDFERVLKINLTGAFNMTQSVLKPMIKARQGAIINVSSVVGLTGNIGQANYAASKAGM
                     IGFTKSVAREVAARNICVNAIAPGFIESDMTGVLPEKMQEQILSQIPMKRIGKAQEVA
                     HLASFLVEQDYITGQVIAIDGGMTMQ"
     gene            complement(114177..115115)
                     /gene="fabD"
                     /locus_tag="VB649_000382"
     CDS             complement(114177..115115)
                     /gene="fabD"
                     /locus_tag="VB649_000382"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEP1669363.1"
                     /translation="MTKTAFLFAGQGAQKLGMARDFYDNFAIVRKTFDQASQVLGYDL
                     RRLIDSDELKLNQTSYTQPVILTSSIAIYRVLGLHHVKPDMVAGLSLGEYSALVASGA
                     LSFEDTLSLVAKRGRLMEEAAPQGSGKMVAVMNTDVQVIEEVCQIAAKHGVVAPANYN
                     TPSQIVIGGQTDAVNVAVELLKERGVKRLIPLNVSGPFHTALLEPASRLLAKELERYN
                     FSDFKIPLVGNTEANIMEKDRIPELLARQVMEPVRFYDSVATLVESGITQFIEVGPGK
                     VLTGFVKKIDKNLLCTSVENMVSLRLFLDREDIHGN"
     gene            complement(115140..116111)
                     /gene="fabK"
                     /locus_tag="VB649_000383"
     CDS             complement(115140..116111)
                     /gene="fabK"
                     /locus_tag="VB649_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEP1669364.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDRPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHQAGIIVVPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMSLVRQVVEA
                     VSIPVIAAGGIADGHGAAAAFMLGAEAVQIGTRFVVAKESNAHQNFKDKILAAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKAFLIGQKTATDIEEMGAGSLRHAVIEGDVVN
                     GSVMAGQIAGLVRKEESCETILKDIYYGAARVIQNEAKRWQSVSIEK"
     gene            complement(116312..116536)
                     /locus_tag="VB649_000384"
     CDS             complement(116312..116536)
                     /locus_tag="VB649_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEP1669365.1"
                     /translation="MAVFEKVQEIIVEELGKETEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKSK"
     gene            complement(116597..117571)
                     /locus_tag="VB649_000385"
     CDS             complement(116597..117571)
                     /locus_tag="VB649_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEP1669366.1"
                     /translation="MIFSKISQVAHYVPQQLVTNNDLASIMDTSHEWIFSRTGIAERH
                     ISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATS
                     AFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDG
                     AGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIF
                     DFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMR
                     YGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI"
     gene            complement(117572..118006)
                     /locus_tag="VB649_000386"
     CDS             complement(117572..118006)
                     /locus_tag="VB649_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP1669367.1"
                     /translation="MEYDKINQYLVDIFNRILVIEEMSLKTSQFSDVSLKEMHTIEII
                     GKYDQVTPSDIARELMVTLGTVTTSLNKLEAKGYIARTRSRSDRRVVYLSLTKRGRLL
                     DRLHAKFHKNMVGHVIADMSDEEMQALVRGLGNLHQFLEDLV"
     gene            complement(118083..118874)
                     /locus_tag="VB649_000387"
     CDS             complement(118083..118874)
                     /locus_tag="VB649_000387"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEP1669368.1"
                     /translation="MQFKHIIFDVVDDLATLTLNRPEVSNGFNIPICQEILVALAEVK
                     RDTSVRFLLIKAVGKVFSVGGDLVEMQEAVAKDNVQSLVKIAELVQEISFAIKHLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGITADKGLDYGFVYRTAESDKLDKVCLQLLKRLRRGSSNSYAGMKSLVW
                     QSFFTGWEDYAKAELAIQEELAFKEDFKEGVIAFGERRRPNFQGK"
BASE COUNT        35724 a        25440 c        21112 g        36660 t
ORIGIN      
        1 tcatattttt tgagaatttc tagcccagaa ttgggactaa tcttttttca aactaatttt
       61 acgtaagatt tacttaaaga ggaactgtaa tagatacttt tgttagcata atgactgtcg
      121 tatctatcac ttaatctcat tttcatcatg tcacctctaa acatgaatag ctttttccca
      181 cttttaaaat acgtataatc atccctgtag gttttagttg tgaactattt agcttctatt
      241 aatcctaggt ttccatcttc gcgacggtat aaaatgtttg ttgcgccatc ttcagaatca
      301 gtgtagataa agaaatcatg tcccaatagt tccatctgta aacgcgcttc ttcaacatcc
      361 attggtttta atgtcacatt tttagtacgt acaacttgta cttctggtat ctcatcgact
      421 tcttcagctt caaactcagt tgtaaagact tgaccagttg gaaccttttc gcgatgtttt
      481 ttagcaattt tggttttatt ttttctaatt tggcgttcga tcttatcaac aactaaatca
      541 atagagccgt acatatcctg tgaaacatct tcagcacgaa gggttactga atctaatggg
      601 atcgttacct caacttttga agatctctcc cgataaactt ttaaattaac acgtgcatct
      661 atttcttggt ctttagcaaa atatttttcg attttagtaa gctttgattc tacataatcg
      721 cgaatagctt ctgtcacttc gatattttct ccacgaatac tgaacttaat cataggatac
      781 ctctttctcg cgcttgaagc gcttacttta tctttaatac tattatactg ctttcatgaa
      841 aatttgcaag ttttaacgtg caattgacaa acttttaatg tcactatttg ctactttagc
      901 caattgtttt ctaagagcga taattgtact accagtagta taaatatcat ctactataag
      961 gattttatca ggaatgtttg atacttttag tagtcgataa gatttttcta ctaataatct
     1021 ctcttttttt gttctggaag attggtgagt attatctagc ttttcaaaaa gagaaaggta
     1081 gctaacatta gctgcctcaa gaatagcgct cacttgatta aattgtcttt ctcgaaaaca
     1141 accgggactt acaggaaccg ggactgggat atagccttta tagtacttgg tgataacatc
     1201 ggcaagttct actgcaaaaa cttttcttaa taaatagtct ccttgaaact tatattgact
     1261 gaagtatgct ttcatagcag cattataaca atataagctt ctatgattta cattgtatcc
     1321 tttgttttcc cattttagac aatctcgaca agctattata tctgagtttg cacaacatgt
     1381 cgcacaaaca ctttttccta tcttttgaaa gcttttttga cattgttgac aaatcggtga
     1441 agagatacgc cttaaaaaga tgatttctgt aatacttatt ggtgtttgac taatttgttg
     1501 acatagtaga cagatcatgc gaataccctt tataattcat ttctttaatc tcttttcttg
     1561 ctagtagcat tgctttactg ataccttcat gaaagaaata taacgttccg tctggtctgt
     1621 ctatagatct tccaactcgt ccagcaattt gaacaagact ttgggaacta tagacacgat
     1681 gatgagaccc aagaacaaaa acatcaattt ggggaaatgt cacacccctt tctaaaattg
     1741 ttgttgtaat taaaatcgtt tttttccctt gacgaaaagc tgtgatatct tctttcctgt
     1801 tttgtgattg actagaaaca caagctattt gttcggcggg caataactct tttaagattg
     1861 ctgtaacaga ttctgccatt ataatagtgg gtagaaaaat taaaagggga tagcctgttt
     1921 ttctttgttt ttttaagtat tttaaaattt taggaggaag tttttgccga tgtatcattt
     1981 taaatagatt aaaacttctt ataaattttg gaataactaa tggcctatta tgaaagcgtc
     2041 tcgccaatgt cagcttgact acttctccct tgtttacctt tctttctaaa gttctagttg
     2101 aagttgcagt taataaaatc tttgcgccac cttcttttaa agcctgactt gcagcataat
     2161 gaagttgaat attatttaca aaagggaatg cgtctacttc atcaataatt aagagatcaa
     2221 aagccttgtg aaattttagc agctgatgcg ttgtggctac tataatagga gctctttgat
     2281 aaggaagaga ctctgcgtgc attaaacaga tgctgcagga gaaggcttgg gataaacgag
     2341 tagccacctc tacacaaaca tctactcttg ggctggcaat gcaaacccag ccacctgtgt
     2401 taattaccgc ctcaatcgca gcataaatca tttctgtttt tcctgcacca gttacagcat
     2461 gaactaatgt tgttttttga ttttgcatat tgattaataa ttgttgggaa attatctctt
     2521 gataagcagt tagttgaccg ctccaaacca gataattacc ttttggaaaa tgcataggtg
     2581 ggatagcata gagcaattta tctgattgat ttcgtccaaa gacaagacaa aatcggcaat
     2641 aataggctcc acttggcaat cgtgcttctt catcaagctg ataatgacaa cgttgacaaa
     2701 tcatttttcc tctcaatatt actacacttt ttaaaggttg agcaagctgc tttgctgaat
     2761 ctggtaactg gctttctagc aacaaccgtc cataactatt ttcaatagac tccatacttt
     2821 attattcgct tttttttgct aatttttatc ttttcttgta caattttttt atggaacatt
     2881 ttaagacaat caaagccagt ggttttttcg aagaaagtat taaaaaatct cgtttcattt
     2941 gtcatatcaa acgagtgagc actgaagaag atggtaagaa ttttgttaat gctatcaaaa
     3001 aagaacatta caaagctaat cattcctgct ttgcgatgat tatcggtaac aacagacaga
     3061 tcaagcgctc aagtgatgat ggtgaacctt caggaactgc tggaatacct atcctttctg
     3121 tgttagaaaa gcagtgttta acaaatgtag tagttgtggt aacgcgttac tttggtggta
     3181 ttaaattagg aacaggtggg ttaatcagag catactctaa catgaccgca acagctatta
     3241 aacgatttgg catcattgaa gttaaacagc agataggact agaaatcaca ctttcttatc
     3301 cccaatatca actatactct aacttgctag atcaattggc tttaaccgaa acagaaacta
     3361 agttttcaga cacgataaag acaacacttt attgtgatac tgaacgtgtg gaaaatctca
     3421 ttgatacttt aacaaattat tatcatggtc agataagctg tgagaaaatc ggatccaaag
     3481 ttattgaatt cccctgtgat taatcatcaa caaaagtgat atggctttat tatcagagtg
     3541 atagtaaatc tgtattttac tttaataata tctctcctta tacttaaata cacagcgtat
     3601 ttattttgta tcaagaaaag aggctaaact atgactaaaa tttacaaaac tataacagaa
     3661 ttagtaggtc aaacacctat tatcaaactt aaccgtttaa ttccaaacga agctgctgac
     3721 gtttatgtaa aattagaagc ttttaaccca ggatcttctg ttaaagatcg tattgcttta
     3781 tcgatgattg aagctgctga atctgaaggt ctgataagtc ctggtgacgt tattatcgaa
     3841 ccaacaagtg gtaatacagg tattggtctt gcatgggtag gtgctgctaa agggtatcga
     3901 gtcattattg ttatgcccga aactatgagc ttggaaagac ggcaaatcat tcaggcttat
     3961 ggtgcagagc ttgtcttaac acctggagca gaaggtatga aaggggctat tgcaaaagct
     4021 gaaactttag caatagaact aggtgcttgg atgcctatgc aatttaataa ccctgccaat
     4081 ccaagcatcc atgaaaaaac aacagctcaa gaaattttgg aagcttttaa ggagatttct
     4141 ttagatgcat tcgtatctgg tgttggtact ggaggaacac tttctggtgt ttcacatgtc
     4201 ttgaaaaaag ctagccctga aactgttatc tatgctgttg aagctgaaga atctgctgtc
     4261 ttatctggtc aagagcctgg accacataaa attcaaggta tatcagctgg atttatccca
     4321 aacacgttag ataccaaagc ctatgaccaa attatccgtg ttaaatcgaa agatgcttta
     4381 gaaactgctc gactaacagg agctaaggaa ggcttcctgg ttgggatttc ttctggagct
     4441 gctctttacg ccgctattga agtcgctaaa cagttaggaa aaggcaaaca tgtgttaact
     4501 attttaccag ataatggcga acgctattta tcgactgaac tctatgatgt accagtaatt
     4561 aagacgaaat aaaaaagggt ttggaactac taaggttcca gactcttttt agtgttcttt
     4621 tttaaaaact gcaggctttc ttcaatccac tgaggtaact gctcttcaag tggcctaaag
     4681 ccaatcttgt gccgactgtt ggaataacga tgacgatgaa aaaaatgctg tttttcttct
     4741 gctaaggtcc gcatagataa acttgccttt ttactatatt catcaatatc aattacttgt
     4801 actaaaacct ggttgcctat agccaataat tgatcaatat catcaataaa tcccgttttt
     4861 atttctgaaa tatgaatgag acctgttgtc ccattgtcaa gggcaacaaa ggctccgtat
     4921 ggtttaatcc cagtgatggt gccatgcagt ttgtcgccaa ttttcattag tcaaatacct
     4981 cgattgtttc aatgataacg tcttctttag gtttatcctg tgcgccagtt tcaacgccag
     5041 caatcaaatc caaaacttgg aatgaagttt cgtccacaag ctgaccaaag accgtatgac
     5101 gacgatcaag gtgaggagtt ccaccatttg cagcgtaaga agctgcaatt ggagccggcc
     5161 aaccaccacg ttctagttct tttttggcat aaggaatctt actattttga acaataaaga
     5221 actgactgcc gttagtattt ggtcccgcat tagccatcga caaggcccca cggagattat
     5281 agagttcatc cgaaaattca tcttcaaaac tttcaccata gatggattgt ccacccattc
     5341 ctgttcctgt tggatcgccc ccttgaatca taaattcagg aataatacgg tggaagataa
     5401 tcccatcata gtacccttct ttagccaaac ctaagaaatt ggctactgtt ttaggagcat
     5461 gatctgggaa caagaccagg gtcatatcgc catggtttgt tttaatggtt gcttttggtc
     5521 ctttatggtt tggcaaatcc aattgtggaa actgtaattc tttgtcaatc aatcctaatt
     5581 cctccaaggc atataaaatg ccatcttctt caaccttttt tgtgataaaa tctgcttttt
     5641 cttgcagtaa tggatgtgat actcccattg caatactgat accagcatag tcaaataact
     5701 ctaggtcatt gagttcatct ccaaaaacca aaatgttttc aggttttaat cctaaatggt
     5761 caactacttt tgaaacacct agcgcttttg acgtaccttt caagacaaca tctgatgagt
     5821 tatcgtgcca tctgaccaaa cgaaggtgct ctgctaattc agcaggcaac tgcaagccat
     5881 ctcccttgtc ctcgaaagtc cacatctggt aaacatcatg atactcatta taatccggac
     5941 agacctctag ttgagcgtag acattatcaa tagcattgct aatcatgtca tttcgagcgg
     6001 acaacaccgc ttcatgacga cccgccattc cataaaaaat gcccatatca tccgcccatt
     6061 ttttataggc cacaacaaca tctgctggaa tcggagcttg gaaaataata gttttagcat
     6121 cgtctttgac ataagctcca tttaatttga cacaatagtc agcatgtaaa tcttgaactt
     6181 cttgtggaac accgtaccga gcgcgacctg aagcaatacc aaccaagatg ccttttgcct
     6241 tcaaagcctt aaatactctt tgaatcgact caggcatata acccgtatct ttgaccctca
     6301 aggtatcatc aatatcaaag aacaccattt tgattttttt agctttgtat tttagttttg
     6361 cgtccatact ttcctccaat ttgctatacc ctatattata gcattaatta tcgtcttggg
     6421 ggactaaatg gtgtcgaaaa gcatagacaa ccgcttgggt tcggtcatca acttctaact
     6481 tggctagaat attggacaca tgtgttttga cggtttttaa ggaaataaag agttcatcag
     6541 cgatggtctg attatcatac cctttagcta aaaggtgtaa aatatcatac tcacgcgctg
     6601 ttagttcctc atgcaagtca gggtgttgat catgcgcctt aatttttttg tcaacttctg
     6661 tttcaatagc taactctccc tttgaaacct tgcgaatggc atttaaaatt tcagccgcac
     6721 tcgatgtttt taacatataa cccttcgctc ctgcatcaat gacagggtat atcttttcat
     6781 tatctagata ggaagttaac acaagtacct tagcctcttt ccattttttt aggacttcta
     6841 aagttgcctc aacaccgcct aactctggca tcactagatc cataaccaaa acatctggct
     6901 tcaaagccaa tgccaaatca accccttcac gtccattaga ggcctcacca acgacatcaa
     6961 tatcagcttg taaattcaaa aaactcttga gtcccatgcg gaccatttca tgatcatcga
     7021 ccaatatcac ttttatctta ctcatcgtca tctcccttca ctatcggcag tctaatatcc
     7081 atggaaactc ctttgccttt ttgactaatt aaatgtaggt ttcctgctaa atcattgaca
     7141 cggtcttcaa tattcttcag accataactc aaatccctta cctgatccat atcaaatcct
     7201 acaccatcat caatcatctt caattgtaat tctgttgagg tttgattgag ataaacttca
     7261 attcgactag ctttagcatg ttttaacgtg ttgctaatga attcttgggc aattctaaaa
     7321 agattatctt ccattgtttt aggaagctga gcaatggttt ccttataaat gacttcaata
     7381 tcacttttat ctgttaattc cttaagaatc atatgaaggc cctcagataa agtccgatta
     7441 gctagctcgg taggtctaag atgcaaaagg agaatgcgta gatcattttg agcattttgc
     7501 aacattgctt caaccgttgt taactgtgtt tgtaattgtg ttttgtccag ttgttccaaa
     7561 ctcatcgaaa ttcctgataa aatcaatgac gaagcgaata gctcttgact gactgtgtca
     7621 tgtaaatctc ttgcaattcg tttgcgctct tgttttacaa cttcttggct atcaagaata
     7681 taagcacttt ctttcttttg catgttagca gtcaggtgag acattttttt agaaagtcga
     7741 cttaaattag tattgatttc tgatgtctca tctagataga gtcgtcgatt attgagaata
     7801 tattttagat tttggttgat gttacgctta ctgttatcat ccataataat ccacaataac
     7861 aacaataata aagtcacaga aacaatcaac aataaaatcg aaaaccctag acgttcgacc
     7921 tgccataaat gattgcgaag gtagttaaaa gtgattccta aattatccat gaccacaaaa
     7981 acaatagata gaatggtaat ggttgagtag agccaaacaa gagcatagta acgttttttc
     8041 atcgcctatc cacctcaaca tttccggcaa tagttgtaac gataattttg acttttttaa
     8101 gggattggtt atccgtttct tttaacttaa tagattcgtt gcgcaaatca tattgctgac
     8161 atctaaaaaa atcaacgctt ccgtatatgg aactaacatc taaagtaaca gtgacatcaa
     8221 taggtaccaa tatagtcgta tttccaaaaa ttttacgtat cacaatgata ttatccattc
     8281 ctgtcacaat aacattggtt aagtcaaccg tgtcatttcc tgagattcga atgatgttaa
     8341 tgtcatcaaa acaataataa tcactttcat aattagcagt accaatccat tgatgcttgg
     8401 tattgttcac ttcaatcttt tcttccttga aacgaatcaa ggcaaagcga ttcttctttt
     8461 tgacttgtga aaaatggtta atgaaaatgt aaactatccc caaaagaaca gccatgataa
     8521 tgtagggatt aagcatgaaa attaaaaaaa gaaacaataa actgacagtt agtaaaaaat
     8581 tattgcggct atcttggtta taaaagcgta atgctaataa gataagaact agaattagga
     8641 taaaacttga taaatcatta tccaagattg tcatgatacc catagctagc agtatacact
     8701 cgataagtaa aaagaattga aattttttca ttagtttccc cttatttctt tgtattttat
     8761 cagaattcct ggaaaattgc atctttatat gacgagtagt taaaaagaat agttagtggc
     8821 atgccagtaa aacatgagac taactattct ttgttaaggt gtttgagaag tagtttctga
     8881 tgggcttaat tcagtgttgc tacctggtgc agtactatca tttattgaag aactgtttga
     8941 acttgacgtt gaactcgatg agctactaga agagtgtgtt tcttctggat aaaggtaaag
     9001 actaatctct cctttatcag acagactcaa agacgttcca tagtaaggag attgaccact
     9061 gacaatagct ttagaactag gagaatgaat tggcacaaag cccgttgctg agctagagct
     9121 tggcacataa gcttttattc tagatgcatc tatacctaaa gctgttaagg tattgactgc
     9181 atctgcataa ctatattctg ttaccatagg catagtgatc gtatcactaa cagcaacact
     9241 gagcgtaatt ttagactttc cgtttggatt aaatttatca cccgcacttg gcgattgact
     9301 gatgactgta ttttcaggat attcattagt tacaatgcgc tcaattttga tttttgattt
     9361 tggaacacca taagtttcta tcaaactatt catagcttct tgataatcta gtcctttgta
     9421 gttttccatg tcaaaacctt tgtttccaat tgacacataa agcgtaatgc ttgagccttg
     9481 cctcttagct gttcctgctt taggatctgt tctaactaca tttccctcag caaccgtatc
     9541 actctcaatt tgcctgattt tacccacttt tagcccaaca tcatacagtt cttgtttggc
     9601 aactttaaga ctagtgcctg ctacattagg aactttcaca gaagttggtt tagttagtat
     9661 aagataagta aagagtgcta cacctacaat aaagaaagaa aaaagaattt tgaataaagt
     9721 acctaaaaaa cgaccacttt ttttcttttt ggtggggggc tgtaaagcat ctgtttgatt
     9781 agtttgatct aatcgacttt cctgtgttaa cactgttggg gtagggggag acaattttac
     9841 agaagcggtg ggacctgagg ccactttggg gaggggtttg gtactttcaa catcctcaaa
     9901 gataatctta cgctcccgac tacgattata actaagcgcc gtcattaagt cacgactcat
     9961 ttcaaaggtt gacccgtaac gatcacttaa tttcttggct gttgctcgaa taacaacatt
    10021 ctccaaagct tgtggcacat tgtggttctc ctcgataata gatggaagag gcttttgaaa
    10081 atgttgcaag gcaatcgtaa cagcactatc gccatcataa gggatatggc ctgtcaacat
    10141 ctcaaagagc ataatcccca tcgcataaat atcactttga atcgtcgctt tggagccgcg
    10201 agcctgttct ggagacaagt aatgaacact gcctaacatc gaattagttt gtgtcaagct
    10261 tgtttctgca aaggctactg cgatgccgaa atcagttact ttgacaacac cctccttagt
    10321 tagtaggata ttttgaggtt ttaaatctct gtgtacaatt cctttttggt gggctaaagt
    10381 catagcagaa aggacttctt ccataattct aaccacttca ttattagata atggagcatg
    10441 attttgaatg tatctcttta ggtcagcacc atccacatat tccattacta aaaattgctg
    10501 tccgtcttct tcacctatat cccggatggc aacaatattg ggatggttca attcagccat
    10561 ggcccgcgct tctcgttgga aacgcgcaac tgctacctga tctgtttgat aattggtacg
    10621 caagaccttg attgcaacgt cttcattatc caagatcaag tcatttgcta aataaacatc
    10681 cgccatacca ccgcggccaa tagatttcag aatgcgataa cgaccagcaa ataatttgcc
    10741 aatctgaatc attcgacgtc ctcactttcg ttatgaacca aagcgattgt aatattatcc
    10801 aggcctcctc ttaggttagc taagtcaatc atttcttggt ttttttcatc aagactaacc
    10861 ttactgccca agatagtcac aatttcatca tttgaaatca tattggttag accatcactg
    10921 ttaatgacaa gataatcccc tggctccaaa accctcactc ctaaatcagg ctctactggg
    10981 gaagcttgac caatagattg agtgataata tttctttgtg gatggctagc agcttcttct
    11041 tctgtgatct gtcctgcctt aaccaactca ttcactaaag aatgatcact ggtcaataag
    11101 gtataatgcc catcatggac aagaccaatc cgtgaatcac caatatgagc ataaatggcg
    11161 ctagattcaa ctaaagctac tgcttcaaca gtcgttccca ttcctttaaa gtcttctgat
    11221 tggcctagat cataaatccg ttgattttct gactggatag tttcaaataa ccaatctcta
    11281 atctgactta actctgtgaa gtctgttttt acccattctc ttcccaggtc tgtgactgtc
    11341 atctcactgg caatatttcc agctctatgg ccacccatac cgtctgctaa aatcactaaa
    11401 gtgatgcctt ttttattatc aaacttattg ataaaatctt gattgtttga gcgtttttgc
    11461 ccaatgtctg tttttaatga aatcttcata cgttttttct gactcagtca gtttcctcct
    11521 aaaatactac aagactcgtc tgacttgtcc aataaagaag ccatcagtct ggtattgttc
    11581 tggtgtgata ataagataac catccttgac aatatctgct tgtgtatggt tcagttttac
    11641 ttgttcaaaa ttaggatgac tctgtaaaaa tgcttcgatg acttgacgat tctcctcatc
    11701 aaaaatagtg caagtactgt atgttattat accaccttta cgcaaggttt gacaaacact
    11761 agacaatatc tctagctgga tagcctgtag agcattaaaa tcttgacttt ctttattata
    11821 tttgatatcg ggttttcgac gaatcaaacc aattcctgag caaggagcat ccaccaaaat
    11881 cttatcaaag ctatcctttt caaaatgacg atgaacctct ctggcatcta gttttcttgt
    11941 ctcaatgtta tcagcaactc ctaagcggtt agcattttcc ttcaccaact ctagtttatg
    12001 atcatagaga tctaaggcaa taactttacc tgtttttaag taagatgcta tatgagaggt
    12061 cttgccccct ggagcgctac atgcatcaag aattatgtcg tcaccgtcaa tgtttaaagt
    12121 aggagctaca agctgactgc tttcatcttg aatagtgatg tccccatttg tgaaataatc
    12181 actggctgca aaatgacctg acgctttggt taaaccagtt gctgataaaa gggaacgttc
    12241 tgcatctaaa gcctcagcaa cttcctctag cttcaaaggg tctgtcacgc gaatactagc
    12301 cttactacgc acaaataaac tctccataat agccactgct ctgtcggagc caaattggtc
    12361 ttctaacttt ttaaccaacc aaacaggcag tgaatacttg accgaataat acttatttcg
    12421 acgcttaatt gtttccatat ctgggagagg atggctggtg aattgacgta aaatagcatt
    12481 gacaaacttc tctgcacctt ttttattgcc acgatttttg gcaataccaa ccgcatcgtt
    12541 aacaatggca tgcgctggta acttatctaa ataaatcagt tgataaagac tgagcataag
    12601 gagataataa acccatttgt ccaatttatc tcggtctttg acataatggg ctaaatacca
    12661 ttccaagcta attttacgtg aaacggtacc atatacaatc tcagttaata gagctctgtc
    12721 cttagcagat aaagctttat tgcttagttg ctgattaagc gctatgtttg tgtaagcccc
    12781 ctgatcaaaa atagcttcaa tgacaaggag ggctttgcct cgcgtacttt ttttccaatt
    12841 atctgccaat gatgtcccct acttcaagtt ttctaccaat gccgtttaaa aagtctatta
    12901 ttgacatttt aggtttacca gccggttgca caacgatcaa ggacaaagca ccttgtccag
    12961 tagttattac caaagatttt ttggttttga caataacttg tccaggtaat ccttctcctt
    13021 cagctagttg agcttcgtaa atttttaaac gttgcccctc taaaaacgta tgcgctaccg
    13081 gccaagggtt catacctcga atatgattga acacttcttg attagacatt gtccaatcta
    13141 atttttcttg ttctggagag atattaggtg aaaaagtagc ttggctgtga tcttgaggaa
    13201 taggttttaa ttctccagaa agataagctg gcaaactatc caaaagtaag tctcgaccaa
    13261 tgatggctaa tttctcaaaa agagtaccta cattatcggt ttcaagaatt ggagtgcttg
    13321 ctttagcgac catgtcacct gcatccattt ctttaatcat ttccataata gtaacgccgg
    13381 cctctttatc tccattcata atagcataat ggataggtgc tccacctcga tatttaggta
    13441 acaatgatgc atgtacatta atagcaaatg aaactgaatc aagtaatatt gttggtaaaa
    13501 attggccaaa tgctgctgta ataataccat ctgcaccaag tcccataatc tcaatgagtt
    13561 cttgagagcc tgataatttt tccggctgat agattgatat tccatgctca agagctaatt
    13621 gctttacagg tgttacctta atatcttttt tgcgtccaac agctcgatca ggctgagtaa
    13681 ccactcctaa aatctcatag gcaggattat ctagcaagcc cttcaataca gttgctgaaa
    13741 attggggagt tcccataaat aataatttta tcatgacttt cctctttgta tttttattat
    13801 atcataactg atcatcctag atttagtgat ttaccttata aaaattgttg cggttcacaa
    13861 tcaataatta gttttaaatg acgattatct gcttcttgac tccaatcaag aatacgattg
    13921 agcgtctctt ctaggttatc ttcaaaacgg tattttaaca aaatttgata gtggtataaa
    13981 ttgtgtgttc tagcaattgg cttaggagtc ggtcctaata ttttaatatt atccgataag
    14041 tgactcttta gcagttctgt aacttgataa gcttttttta caaccgatgc ttctaaacga
    14101 tgcgaaagcg taatacccac tgtaaagtag taagggggat aagccatctg acggcgaatc
    14161 gccatttcat aacggtaaaa ggcttcaaaa tcttgtttct tagctaattg aatagcatag
    14221 tgatcgggat tataagtttg aatcaagact tctcctggct tatgggcacg gcctgcccga
    14281 ccagcaacct gtgttaacaa ttgaaacgtt ttttctgacg ctcgaaaatc tggcaaattt
    14341 aaggaggtat ctgcatttag taccccaact aaagtcacat ttggaaaatc cagacctttg
    14401 gcaatcattt gcgtccctaa caaaatatct gcttcctggc gaccaaaact atctagtatg
    14461 gttttgtgac ttcttttttt tcgtgtagtg tcaacatcca ttctcaagat cctagcttct
    14521 ggaataaccc cttgcaattc atcaaaagct ttttgagttc cagtgccata atagcggata
    14581 ctattgctat aacactcagg acaagtaatt gggataggtt tttgaaaccc acagtaatgg
    14641 caattcatag ttttagtatc catgtgaagg gttaaagaga tatcacagtt gggacatttg
    14701 tccacataac cacagtcccg acacatcaca aaactagaat aaccacgtct atttaacatt
    14761 aagacaactt gttctttttt aaccaaacgt tctttaatct tatcaatcaa atatggggta
    14821 aaattactaa ctgcttgctg tccaatataa tcacgaaaat caacaatcgt tacttctgga
    14881 atcttagcaa gagggtttgc tctttgcgtt aattgaataa aatgatagac acccttacta
    14941 gcccttgctc ggctttcaat acttggcgta gcagagccca taaccacaac tgcttgatgg
    15001 tgtttagctc tgagcagggc aacctctctg gcatggtatc gtggattact ttcttgttta
    15061 taggttgatt catgctcctc atcgataata attgcaccaa tccgctctag tggggagaaa
    15121 atagcagagc gggcaccaac cacaacctta gcctgtcctg tttttatctt gcgccactca
    15181 tcaaactttt caccatctga taagcctgaa tgcataatag ccacttgctt tccgaaacgg
    15241 gaaataaaac gagaggtcat ctgaggagtc aacgaaattt ctggcactaa aacaatggct
    15301 gtcttatcct gttttaaaac cgcttcgatg atatgaagat aaacttctgt cttacccgaa
    15361 cctgtaatcc cttcaatcaa aaaaggttta ctcggtttcc caatttgctc aacaatttca
    15421 gtaacagctg atgcctgctg ttcatttaag gttaaaaaag aagatggttt gatctggtca
    15481 aaatagggct cactgcgatc aattggacgt tcgtcaatac gaattaagtg atttgtcaca
    15541 aagtaagcca ccacgtctcg agaaaaggct tgataaagcg ttgcaagttt agcttccttc
    15601 gtatgggtta gcagatagtc ttttaataat tgacgctttt tggcacgact agagatggga
    15661 tgtaccgcta aggcgtctaa gtcgacgtga taatattttt ctgtctttag gtttttcttg
    15721 tctttggcta aataactaac agtaatatgc ccagcttgta tggccttaag agctattttt
    15781 tccttctcgc ggtctaaggt agaatataag acagatggtt ttccttcaaa aagaaagtct
    15841 ctatcaggct tttttagacc tgactctggc cttagcactt tatcatagtt agagttaaga
    15901 agattaggaa tcattgcttt taagagcgtg attttataag aaaaaactgt ttttcgaagc
    15961 tgatcagcaa gggtcaattg ttcttggttt aggactggct caggatctaa aacggtctga
    16021 atcagtttaa gagagcttga atcttcttgg ccaaaaccaa taataaagcc ttgcaacaaa
    16081 cgattccctt ttccaaaagg aacatgcaca cgagaaccaa gctgcacgag agaaactaac
    16141 tcttttggaa taccataaga aaatggcttg tccgtttgca tcaatggaat atctacaatc
    16201 acatgagcta ctttttccat ttgcttctcc ttttctgtca tggacatcgt actaaatatg
    16261 aaaaaatcta agatttctga aaccttagat tttttctcct tcttcttctt tttctttggc
    16321 aatttgttct ttgattttac gttcctcttc ctctttggcc aagcgttctg cctcaatctt
    16381 agcacggaca gcttcacgtt tagctgaagg atctgggtga atcacaacgt ttcctgattc
    16441 aatttcttca agtgcctgaa gtgttgactt cactgattta aattcttgag ttggagtggc
    16501 accagcttct agttcatggg cacgtttggc ttgtaaaatc acaagtgaat acttggatgg
    16561 tactttatct aataaggtat caatggaagg ttttaacatc ataatgctta ctcttttcta
    16621 tttagcttta aagggatttt ttgttatttt aatcatttta tcataacgac caatcacgcg
    16681 ctccacacga aaatgttctg tctcaatgat acgcttaacc cgctcagctg ccaaggcaac
    16741 ttcatcatta acaactgcat aatcgtattc gcgcataagg gcaatttctt cttttgctct
    16801 ttcaatacgt tgagctatga cttcttgact atctgtacca cgaccaacca ggcggtcttc
    16861 taattcatct aaatctggtg gtgttaaaaa aacaaaaaca ccatctggta cttttgactt
    16921 aacctgaaga gctccttgaa cttcaatttc taaaaagaca tcaattccct tatcaagagt
    16981 ctcattaaca taagttaaag gggtgccata gtaattacca acatattcag catactctag
    17041 catttgacca gttttaatga gttcttcaaa ttcttctcgt gtgcggaaga aataatcaac
    17101 cccatcaacc tcgcccggtc tttgcggacg agtcgtcatt gaaaccgaat attcaaattt
    17161 atgatctggc gttgaaaaaa tttcttgtct caccgttcct tttccgacac ctgaagggcc
    17221 agaaaagacg attaacaaac cgcgttcaga cattgtattc tccttattag ttgcttttta
    17281 atagtttatc aaaaaggcta gtctttttca agaacatttt caaaggcaag tcataaagaa
    17341 aaagaggata attcctcttt ttctacttgg cataatcaac cgctctcatc tcacgaataa
    17401 cagttacttt aatatttcct gggtaatcta gattgttttc aattttttct cttactttat
    17461 gcgacaaaat gacaacctga tcatctgaaa ttttttcagg ttgaaccata atacgaatct
    17521 cacgtccagc ttgtagagca aaactatttt gtaccccatc aaaacttgtc gcgatttctt
    17581 ctaaatcacg aagacgcttg atgtaattct ccattgactc attacgagcg cctgggcgag
    17641 ccgaactgag agcgtctgct gcagctacta gcacagcgat cacagaatct ggctccacat
    17701 ctccgtggtg gctagcaata gtgttgacaa caactggatg ttctttgtat ttacgtgcaa
    17761 attccattcc aatctcaacg tgactacctt caacctcacg gtcaatagct ttacccatat
    17821 catgcaagaa accagcacgg cgggcaagag caacattttc acctaactca ccagctaaaa
    17881 taccagctaa cttaccaacc tcaacagagt gacgtaggac attttgacca aacgaggtac
    17941 ggaattgcag gcgtcccatg attttaatca aatcaggatg aaggtttggt gcaccaatct
    18001 cataggctgc agcttcaccg tactcacgaa tacgattatc catttcaaga cgatttttct
    18061 caaccaattc ctcgatacga gctggatgga tgcgaccatc agcaatcaga gattccaagg
    18121 tcatacgagc aatttcacgt cgaataggat caaatcctga taagataaca acttcaggag
    18181 tatcgtcaat aataacgtca atgccagtca agctctctaa agtacgaata ttacggcctt
    18241 cacgtccaat aattcggccc ttcatgttgt cgtctgggag atggacactg gtaatagttt
    18301 gttcagtcac atactcacca gcaaggcgtt gcatggcttg cgctaacaag tccttggctg
    18361 ttttaactgt tcggtccttg atgtcacgtt cggcatctcg aatgcgcgtc gcaatttcat
    18421 gggtcagttt gttttccgtc tccattaaaa tcacttcacg cgcttctgca atcgtcatcg
    18481 cagcaacttt ttccagttct gcttttttct cctcttcaag tttttccact tgaagttgcc
    18541 gctcatcaat gtgtttagat ttatcggtca gactttgttc tttactatct agtacctttt
    18601 ctttacttga taggttttca tctttacggt caagagttaa ggagcgctcc gctaagcgtg
    18661 tctcgagttg tttaagctct tgcctttcag acttaaattc ttgttcaatc tcttcacgat
    18721 attttcttgc ctcttctttt gcttctaaaa gtaattcttt acgatttgct ttactttcac
    18781 gtttagctgt ttttttgatg tgttcagcat ctacttctgc tttgccacga atatcaacag
    18841 cttcttgttc agcgtttaaa agagtcaact ctgcagcttc cttcgcagac ttgagtctaa
    18901 tcgaaataag tgcataacct aatattaaac caatgagggc agaaacaatt aataaaataa
    18961 tattaaccat gtttgtacct caatatattc tagatttcat taatagaaag ccatctctta
    19021 gtttatcata aattgagcgt ttacacaatt ccaattcatt tttaaaaaaa ttaacatttg
    19081 ggccaagtgg ttgagaatcc tacttaaaaa aagactgtag caagtcgtcc atgatgtagg
    19141 cttctatttc agaataactt tttttccgga ggcgtgttaa gacaacacgc caagaaatgg
    19201 gacgttccat tggaatacac ttaatgtcct ttaattggta taattctgta ataggtttgg
    19261 gacaaatagt taagacgttg tgattaatct tggtagaatt aagcataaaa tcccaggaag
    19321 aggacgtcaa aataatatta ggtctgactt ggtgacgctc gcaagcttca agcactaaat
    19381 ggtgaaccat gaaactagga tcaaataggg caagttgttc atctgttaaa tcttcccact
    19441 gaataacttt tttggaagct aaacgatggc gtggagacag gcatacagat aattctgatc
    19501 tctggatttc ataagtctca accaaattat cagcgatgcc tgttggggat aacaagactg
    19561 cgacgtcaac atttcccacg agtagttcat tttttagttg gtaagcacca atctccttaa
    19621 cattgaattg aatccccgga ttttctaaaa tcagttttgg cattacttct gagaaaacaa
    19681 ctgataaaat aagaggagga ataccaatat tgatacttcc cattaaccct ttactgtgat
    19741 catgcaattt caaaaacatg tcatcataga gactgagaac cttttgagcg tccttataat
    19801 aattatcacc aagataggtt aacccaataa tacgacctct ttttcgtttg aagagcttaa
    19861 cattttctct tttttcaaaa tcgttaatca tcatactcag cgtcggttga gaaacatata
    19921 gtaattctgc tgcttgactg agattaaaat gattttcaac aatggcaata aaataacgaa
    19981 tttgtttaat atccaaatag gattctcctt gtcttatcaa ttgctttttc cggtataatt
    20041 acctatatta tgacacaagt agatgttaaa tgctattgcc aactctatca aaaaaattta
    20101 tatgcttata aaaattctat atttttattt tgagcgtttt cttgttatct cagatacata
    20161 gaaagcgctt tctaaaactg aaaggatgtt tattttatga aaaacatagt tatcgttgaa
    20221 gctttacgaa ctcctatcgg agcttttgga ggctccctta aaagtgtctc tgctgttgaa
    20281 cttggaacaa ctgtactgaa aaaaatcctt gataaaacgc aagtaaagcc tgaaatggtt
    20341 gatgaagtca tcctaggaaa cgtccttcat gcaggcctag gacaaaatgt ggcaagacaa
    20401 gttgcagtcc actcaggaat tcctgaagat aaaacagctt tcacattaga tatggtttgc
    20461 ggttctggac ttaaagcaat ccaattagct gcgcaaagca tcatgcttgg tgacgctgat
    20521 atcgttattg ctggtggtgt cgaaaacatg tcacaagcag cttatgtctc aactcagcac
    20581 cgctttggtc aacgtcttgg taatagtcaa ttgattgata ctcttgttca tgatggctta
    20641 acagatgctt ttaacaatta ccacatgggt attactgctg aaaacgttgc tcagaaatat
    20701 ggcatctcaa gagaagagca agatcaattt gctttagaaa gccaagaaaa agctgctagg
    20761 gcattagaaa atcatcgttt tgctgacgaa attgtccctg tctctgtgcc tcaacgacgc
    20821 aaagaccctt taattgttac aacagatgaa tacccaaaag ttgatacaag ccttgaaaaa
    20881 ttacagcaat tacgtcctgc tttcctccct aaagaaggaa ccgttactgc tgggaatgcc
    20941 tcaggaataa acgatggtgc agccttattg atgttaatga ctgaagaaaa agctcttgaa
    21001 ttagggttaa cacctttagt cactattgaa agctatgcta gtgcaggtgt tgcacctgaa
    21061 ctgatgggaa ctggaccaat tcctgccact caaaaagccc ttaagaaagc tggattaaca
    21121 atttctgatt tggacttagt ggagtccaat gaagcgtttg cagcacagtc cttggcggtt
    21181 ttaaaagatt taaagttaaa cccagaaatc gtgaatgtta atggaggagc catcgcttta
    21241 ggtcatccta ttggtgccag tggcgctcgc attctagtca cattaatcca cgaaatgaaa
    21301 aaacgccaag taaccagagg actagcaaca ctttgcattg gtggaggaca aggaactgct
    21361 gttatcgtga aaaacaatac ttagtctcgt gaaagttggt agaaaaaatg tgtaaagaaa
    21421 tcacaataaa agaagcggta gctcacgtta aagatggtga taccattatg gttggtggct
    21481 tcatgacaaa tggcacacca gaaaaattaa ttgatgcact tgtggaaaaa ggtgtcaaag
    21541 acctcacttt aatctgtaac gatgccggtt ttcctgacaa aggcgttggt aagatggttg
    21601 ccaataaaca gttttcaact attattgcat cacatatcgg tctcaaccgt gaagcgggcc
    21661 gacaaatgac tgagggcgag actgtaattg atcttgtacc tcagggaaca ttagctgagc
    21721 gcatccgcag tggcggtttt gggctaggcg gtttcttaac acctactgga ataggaaccg
    21781 aagttgccaa aggaaaagaa gtcattacta ttgacggcaa agactacctt cttgaaaaac
    21841 ctttgaaagc tgatatcgca cttatttttg ctaacaaggc agataaaaat ggcaatttgc
    21901 aatacgcagg ttctgaaaac aactttaacc atgtcatggc agcaaatgcg aaaaccacca
    21961 ttgttgaagc aagagaaatt gttgacgtgg ggcaaatgga tcctaatttt gtccatactc
    22021 ctggcatttt tgttaactac ttagtgaaag gagcctaaca tgggaacatc agctactgtt
    22081 ctttcaaaag aagagattca aacacgtatt gctaagcgcg ttgcacaaga attagaacac
    22141 aatacactgg tcaacttagg cataggtttg ccaacaaaag tagccaacta tattcctgaa
    22201 ggtgtaacca ttaccctgca gtccgaaaat ggttttgtcg gtctcactgg attaacagat
    22261 gatcactacg atcctactat tgttaatgct ggtgggcaac ctgttagtat tgctcctgga
    22321 ggggctttct tcgatagctc aacttccttt ggtattattc gaggcggcca tgtggccgca
    22381 accgtcttag gtgccttaca agttgataaa gaagctagca ttgctaatta cctgattcct
    22441 ggaaaaatgg ttcctgggat gggaggggcc atggacttat tggtaggtgc taaaaaagtc
    22501 attgttgcaa tggagcatac caataaaggc aaagcaaaaa ttttagacaa atgcaccctt
    22561 cctctgactg ctcaaaatgt tgttaaccta atcattactg aaatgggagt ctttgaatat
    22621 caagatgaag gtctatgcgc ccttgaaatt aacccagatt acacctttga agacgtgcaa
    22681 aacgttaccg aagttaccct aattgataaa acaaactaaa gactaaccaa aagaaagacg
    22741 aggatagtat catgacacat actaaagaag ttgcatttat cactggtgct gcaagcggaa
    22801 tcggaaaaca aatcggggaa accttattaa aagaaggtaa aacggttgtt ttttctgaca
    22861 ttaatcaaga aaaactggat caggttgttg ctgactatac taaagaaggc tatgacgctt
    22921 ttagtgttgt gtgcgatgtc accaaagaag aagccatcaa tgctgctatt gatacggttg
    22981 ttgaaaaata tggtcgtatt gatattttgg ttaacaacgc aggccttcaa catgttgcca
    23041 tgattgaaga ttttccaact gaaaaatttg aattcatgat taaaatcatg ttgacagcac
    23101 catttattgc cattaaacgt gcttttccta caatgaaagc tcaaaaacac ggtcgtatta
    23161 ttaatatggc ttctatcaat ggtgtcattg gttttgctgg caaatccgcc tacaattcag
    23221 ctaagcacgg cttgatcggt ctgaccaaag taactgcctt agaagctgct gattcaggca
    23281 ttacggtcaa tgccatttgt cctggatatg ttgacacacc actggttcgt ggccagtttg
    23341 aagacctttc caaaacaaga ggtattcccc ttgaaaatgt tcttgaagaa gtgctatacc
    23401 cacttgttcc tcaaaaacgc ctcattgacg ttcaagaaat tgcagactat gtgtctttcc
    23461 ttgccagtga taaggcaaaa ggtgttacag gtcaagcctg tatcttagac ggtggctaca
    23521 ctgctaaata aatttggaga gataaagagg ctgtatcttg tgatctgtct ctttattttc
    23581 taataaggag gtcataaaac tatggaaatt attggttctc tgggggtctt ggtaggtgtt
    23641 attgttatta tttacctgtc tgtcaaagaa gttaacatta tcatcgctgc gcctcttgct
    23701 accagcttgg tcattttgtt taatcaaatg gatccaacca aaaccttact tggaaaagaa
    23761 cccaaccaat ttatgggggc actctccact tatattctca attattttgc tatcttttta
    23821 ttaggttcta tcttagccaa attaatggaa acaagcggtg caaccacttc tattgcagat
    23881 tatattttaa aaaaagttgg tcatgatagt ccttataaag tactcgttgc tatttttcta
    23941 atcagtgcta tattaactta cgggggaatc agcctctttg ttgtcatgtt tgctgtcttg
    24001 ccgcttgcac gaagtctatt caaaaaaatg gacttggctt ggaacttaat tcaagttcct
    24061 ctttggctcg gtattgcgac ttttaccatg acgattttac ccggaacacc tgctattcaa
    24121 aatgttattc ctattcaata cttggacacc tcactaactg ctgccgccat tccgagtatc
    24181 gttggctcaa ttggctgcgt gacttttggg ctcttttata tgaaatattg tctagcaaaa
    24241 agtatggcaa ggggtgaaac ttatgccact tatgcttttg acaatgagat acaagtgaaa
    24301 acaaaaaatc tcccacattt ccttgccagt atcttacctt tattgttgct cattattatc
    24361 gccctaaccg gtagcctttt cggaaacgat ttttttaaga agaacattat tttcatagca
    24421 cttttagctg ccattctcac cgcaagctgg ctctttagac agtttattcc taataagatt
    24481 gctgtcttta atttaggagc tagcagctct attgcaccta tttttgcgac agcatctgca
    24541 gttgccttcg gagccgttgt gatgattgcc ccaggtttca cattcttctc agatctcatt
    24601 ttgaatattc ccggtaatcc tcttattagt ttagccgtgt tgacttcctc tatgtcagct
    24661 attaccggct cttcttccgg tgctctagga attgtcatgc ctaactttgc ccagtattat
    24721 ttagatcaag gccttaatcc cgaaatgatt caccgtgttg ccactattgc ttctaatatc
    24781 tttaccattg tgccccaaag tggtgtcttt ctcaccttct tagcattgac aggacttaac
    24841 cacaaaaatg cttttaaaga aacctttatt actgtttctg taagtacttt tatcgcacag
    24901 gtcattatga tagcctttga tctgttttct tagccttttc tcctccacaa gtagccactt
    24961 tctcactatt tgtgttatga taaagtgtaa aacaaaggag attgaaatga caaaagaagt
    25021 tatcgtcgaa agttttgagc tagatcatac tattgtaaag gccccttatg ttcgtcttat
    25081 ttctgaagaa tttggaccca agggcgatcg tattacaaat tttgatgttc gcctagtgca
    25141 gcctaaccaa aattctattg aaacagccgg tttgcatacc attgaacact tacttgccaa
    25201 gctcatccgc caacgcattg atgggatgat tgattgctct ccttttggct gtcgaacagg
    25261 ttttcacctt atcatgtggg gaaaacacag ttctactgat attgccaagg tgattaaatc
    25321 cagcctagaa gaaattgcaa ctgggattac ttgggaagat gttcctggaa caactcttga
    25381 atcctgtggg aactataagg atcatagcct ctttgccgcc aaagaatggg ctcaattgat
    25441 tattgatcaa gggatttcag acgatccttt tagtcgccat gtcatctgat actagtgtgt
    25501 tgtcaaacat aacaatccta ctgacctatt tgacttgtta caaaaacaag tctatctgca
    25561 gattttaaga caacatactt tattaatcaa aaaactgaga caagttgcct tatctcagtt
    25621 tttttgattt tctcagtaat ctaaagcatc agcataacct ttgccatttc ctacaaaata
    25681 acccgtctta caattaatag agaacagata agtgccatca ggcttaaaca tattatagta
    25741 accattgcca ttaataatat taaccggctc taaaatatat tggttgcctg aaatataacc
    25801 tctagcttgt gaggttgcta caattttttc aagaactcct ggattaaatg cccaagatgg
    25861 gttagctctg tcagcaataa catcttgatt gtaaggtaca cgtgataaat gccgttgtaa
    25921 gcttgcaggg tcataacttg tcaagccata gccagatggt gctactgatg tactttgtcc
    25981 ttgagctgct tgagcctggg ctgcttgctc attagctgct ttagcggcct cagccttgct
    26041 ggctagttgc tgacgacctt ctgtgatgct tgcctgcaag acagcatcaa gatttgcatt
    26101 tcctgttgtc aaggttgcac ttgataaatc atcaaaatta gcatcagcct tgacttcagc
    26161 cgaaaccttt tcaccatcta caacaacatc ggaaacaaat ttaccgttaa ccgctgtaat
    26221 agcagcaata gctttcttaa gggaatcgac ttttgctttc gccttatcat agtaagcaga
    26281 gccttccaaa gctttcaagg cagcttctaa atctggcaaa gtagcaaagg cactattttt
    26341 taatttgctc tttgtggcat ctgtataaaa agtaccatat tgtttttcga aagctttagc
    26401 agcagccttc aagcgcgttg cttttctagc actgtcggtc tgcaaagagg tctttgtctg
    26461 tttacttgct gtttgagttg ttttaccact gtcttgtctc aagaaatggt tccaaccaaa
    26521 tacaactgca agaatggcca ataatagcag aaataaagct attaaccaac cttttttcgt
    26581 attttgtttg gctggatggt ggctatcttc agaaagaaac tgatctcttt ttggctcttc
    26641 tttggttatc tgtggttccg gaatgaccct ctctgatgga tctagatcta acacagggac
    26701 tgtcgcttcc accggaatcc cagttaccac cgcagtagtc tccattggag ctaagtcttc
    26761 agctacttct tcaaccaaag tgctatcttg ctcagcagac tccgcagaca caggttcgtc
    26821 atcaacaaga ccggctttac tcaatgcttc tctttgtttt ttgataaagt tatctaaact
    26881 agctgtatca agctctgtat acttagcatc aaacttttga gaagaaactt cgtcacggtg
    26941 ttgcttaatg tacttatcta aaatactatc atccttagta acacctgctt ttatctctga
    27001 ctgtttgcgt acagcttcac caattgtcat tgacttggct tcattaagcc ccaatgtttg
    27061 cgattctttt gttacttcga cttctttgct ttcttctgac acgcttacta cctctctata
    27121 tcagatgtcg ctttaccctt tccccataaa attggtacaa atcaactttt agggtgccgt
    27181 tataaagttt acgtttttta tcagcttttt gcccgtattt tagttcaaaa agttcatcac
    27241 ttgtaaggat aaatttgctc catgttttca atggtgcaaa ggtttgtccc atttcattat
    27301 acaagatgtc aaccgctttg tcatcaagca accgttctcc ataaggagga tttgatatca
    27361 ctacaccatt aatcttgtct gttcgaaagt cttgcagacg catttgctta aaggtaatca
    27421 catcagataa accagcttct tcagcattac ttttagcaat ctcaatcatg cggccatcga
    27481 tatcaaagcc agaaatatct aattcgattt cataattagc ttcttgttca gcatcatcac
    27541 gaacttgttg caccatatct ttatctaccc agctccattc ttcaaaagca aacgaacggt
    27601 taaatcctgg agcaatattc atcccaatca tggctgcctc gatgcaaaac gttcccgatc
    27661 cacaggtggg atcaaccaga ggtttatctg gaaaccagtt agataaggcc aagatagcag
    27721 ctgccatatt ttccttgatc ggtgctccac ctttttgaac gcgataccct cgtttaaata
    27781 ggctagatcc tgtcgtgtca atcataatag tggcttggtc ttttaaaata gatacctcaa
    27841 tgttaaacgt tgacccaact tcttgaagag gaactccttc tggcctgtgg aaatgctttt
    27901 gcagtttctt aacaacggcc tttttggtaa tcgcttgaac acttggctcg ttatgcaatt
    27961 tagacttaac acatttggct tttgagattg gaaatttagc tcctagcggt aaataatttt
    28021 cccaatccaa ggcaaagaca ccttggaata attcttcaaa ggttctagca ggaaattgtc
    28081 ctacgataat tttgatacga tctgctgcac gtaaccaaag atttgtttta acaatcgctt
    28141 ctacatcacc ttcaaaataa actttcccat tttcaacctg acaatcaaaa cctagtgctc
    28201 tgacttcttt accaacgaca gcttctaaac ctgcggctgc agttgcgact aatctaaatg
    28261 tttctttcat atatctcttt cttttaaatc aaataaaagc tagcaagtgc tagcttaacc
    28321 tattatgcaa ttttctataa gccatgtttt gttccggaaa taactaggaa ttatttcctt
    28381 cgataatcat ctgtctaccg tctgttgaca gtcaggatag cttgttcgtt tccaactatc
    28441 ccatgcccct accaaagttt gggttgctag cttgaggggt ttaccgcgtt ccatttttta
    28501 cgtttccata aaaactacgt cactgtggca ctttcagaag tactttggca tatcaaacga
    28561 cttagccatt tccttcgccg taatgtgtat gcacatccct aggcttatgt gttcgcctag
    28621 cacaatcact actggcatca cagccagtgc tagcatggac tttcctcata gtattaaaat
    28681 actacgcgat tatccaaaaa ttgcacagtt ttcattactc aataatttgt ttaccaaaaa
    28741 cctctttttc caatttacta atacgtttca agatgtcaaa attagtagct gattgagcaa
    28801 cacgagtcgg ttgcggtact ggttgttgaa cagtcgctga aactgtattt ctagcttgaa
    28861 acttcgcctt ttttaaggct tcgttctcag cttttaaagc ttcaatttga gcattgaaat
    28921 tttcataatc tttaattaca ttatcaagaa attcatcaac ttctttctta tcaaaccctc
    28981 gcatactagt cttaaattct tgctcaaaaa tatctttagg actataaata atacttgtca
    29041 ttctttactc tccgaacggt caatcttttt accaaaatta tatttcagta ttattaatga
    29101 tacagaaaaa tagttcaaaa agcaagtatt taaataccaa tacccctaaa aatacaatgc
    29161 tagctttgtg acatatcatt tagccgatca aaggttagca atagcaactg ataatacggc
    29221 atatcttttg ctttcttgag aaaatatttt aagttggttt cgttttctgt gtcataaaaa
    29281 acataagccc cttctgtctt ttctaataaa aactgataat attgactaaa ttgcgttggt
    29341 tgttcgtaat ttggaaagta atattttaca aagtcaacag ccctaaactg acttaaaact
    29401 tcttgatttt tttcattcca cttatctcca tgcgtttcaa acaagaatat agtagctatc
    29461 tgcaagggat actcctcttt tagctcatta gctacttcca aagcccattg ttcaaaaccc
    29521 aagttccctg taaagataaa ccaatccaca ccattttcca aataacctat taaatcttta
    29581 cgaatagcct gtttaataat tgaaactcgt gggtctttat ggtcaaaaat ccctatttca
    29641 aagcttcggt aacctgtaat tagaatcgca gtcattaggt gttatccttt caaaaaatat
    29701 gttataataa aagtgcttaa atttttagca ttaactagat aatattagga gaacaatggt
    29761 taattatcct cataatctta ttcgacaaaa agtaagttcc gttcaaaagc aaacaaagca
    29821 aaataaggtg gacttcgcca atagaggtat gtcctttgaa gctgctatca acgcgacaaa
    29881 tgattattat ttatctcgtc aaatagctgt cattcacaaa aaacctactc ctgtccaaat
    29941 tgtcaaagtg gattacccta agcgcagtcg ggcaaaaatc gttgaagcat actttagaca
    30001 agcttcaacg actgactatt gcggcgttta taaaggacat tatgttgatt ttgaagcaaa
    30061 agaaaccagg caaaaaacag ctatgcccat gaaaaatttc catttacatc agattgaaca
    30121 tatggcttgc gttttacatc aaaaaggaat ctgctttgtc cttcttcact tttccacact
    30181 gaaggagact tactacctac ctgctcaagc cttgatttca ttttatcaga tagataatgg
    30241 cagtaaatcg atgcccattg attatatcag aaaaaatggc tttaaggtag catttggagc
    30301 ctttccacaa gtcccttatt taaacataat tgaacaaaat tttttaggcg gtgattacaa
    30361 ttaaaaatcc aaaaatcctt aagtggctaa agtatgtatt aagtgcaatt cttagcctta
    30421 ttatccttgt tattattatt ggtggtcttt tgtttacctt ctacattagc agtgctccga
    30481 aactgtcaga agcccagtta aaatcaacaa actctagctt ggtttatgac ggtaataaca
    30541 atctgattgc tgatttgggt tctgaaaagc gtgaaaatgt aacagctgat agtatcccta
    30601 ttaatctagt taatgctatt acctcaattg aagataaacg tttctttaac catcgtggag
    30661 tagatcttta tcgtattttt ggtgctgcct ttcataatct aacgagtcag accactcaag
    30721 gggggtcaac gcttgatcag caactcatta aactagccta tttttctact aatgaatctg
    30781 atcaaacctt aaaacgtaag gctcaagaag tttggcttgc tcttcaaatg gagcgaaaat
    30841 atactaaaca agaaatcctg actttttaca tcaacaaagt atatatgggt aatggcaact
    30901 atggtatgct gacagccgct aagtcttatt atggcaagga tcttaaggat ttatcttatg
    30961 cccagctagc cctattggct ggaatccctc aagctcctag tcaatatgat ccttaccttc
    31021 atcctgaagc tgctcaaaat cgccgtaacg tcgtgttgca acagatgtac atggaaaaac
    31081 atctgacgaa agcagaatat gaaactgcca tcgcaactcc cgtcgctgaa ggtctacaat
    31141 cactccaaca gcgctcaact tatccaaaat atatggataa ttatctaaaa caagttattg
    31201 aagaagtcaa aaaagaaaca aataaagata tttttaccgc tggtttaaaa gtttatacta
    31261 atattatccc cgatgcgcag cagactcttt ataatattta tcattctggt gattatgttt
    31321 actatccaga ccaagatttc caagttgctt caacgattgt tgatgtgaca aatggtcatg
    31381 ttattgctca gcttggcgga cgtaatcaag atgaaaatgt ttcatttggg actaaccaag
    31441 ctgttttaac tgatcgtgac tggggttcta ccatgaagcc aatcacagcc tatgctcctg
    31501 ctattgaatc tggtgtttat acttctactg ctcagtcgac taatgactca gtctattatt
    31561 ggcctggaac cactacccaa ttgtttaact gggaccttag atataacgga tggatgacaa
    31621 tccaagctgc tattatgcta tcgcgaaatg tcccagcagt ccgagcactg gaagccgcag
    31681 gacttgacta tgctcgatct ttcttaagca gtttaggtat taactatccc gaaatgcact
    31741 attcaaacgc tatctcaagt aataacagta gctcagataa aaaatatggt gcaagtagtg
    31801 aaaaaatggc cgctgcatac gctgcttttg caaatggtgg tatttatcat aaaccaaggt
    31861 atgtcaataa agtggaattt agtgatggta caagtaaaac ttttgatgaa aaaggaaaac
    31921 gtgccatgaa agaaaccacg gcctatatga tgacagatat gttaaaaact gttctcactt
    31981 atggtacagg taccgctgct gccattcctg gtgttgcgca agctggtaaa acagggactt
    32041 ctaactacac tgatgaggaa ctagctaaaa ttggtgaaaa atacggcctt tatccagatt
    32101 atgttggtac attagcgcca gacgaaaact ttgttggctt tactaagcgc tacgccatgg
    32161 ctgtttggac aggttacaaa agccgcttga ccccagtcta cggatcaagt ctagagattg
    32221 catctgacgt ttatcgtagc atgatgactt acttaacaaa tggttacagt gaagattgga
    32281 cgatgccaaa tggtctttat cgcagtggtg gattcctcta cttaagcgga acctatgcga
    32341 gcaacaccga ctatactaat tcggtttaca acaatcttta cagcaataac acgacaacag
    32401 cttctagcca aacgacttca gatgatacta gtagtagcaa tgatacaagt aattcaacca
    32461 atacagacaa caatagcaat catccatcta ccgatgataa aaagacaact cattaatctc
    32521 taactctact tattgtctgt acctaccttt tattacatat ccatttactt acttttaata
    32581 tctaccttaa gtgataatct aaataaaaag cgagtccacg ttctgtgagg actcgttttt
    32641 atatgacaca aatgacctac cacatacaat ataaaacaaa aaacagaatt ctttaatcgt
    32701 attaaagaaa aggtacaacg ttaagggaat tagcaactga tttttcaaac gttaacctaa
    32761 aacaaaatag acttatttaa aattgttata aatagcaact aatgccataa gagagtatac
    32821 atgaaaaaaa cacgtttcca tataccgaag acgtgttttt tcatatgtca ttttcttagc
    32881 ataataattt ttttcatgtt cactttctta tgcggagtcc aatccgtttg ctgttcgttt
    32941 tgtccagctt ttagatttca tacagtcgca aagaaaggaa ttagcattgt gctaaagcac
    33001 ccattggatc ccaaggagct agtacttgtg gctctttttc ataagccgct aactcgtcag
    33061 ctgttaagaa ttctttacgg acaacaattt gataggtata ttcatccatc caagcatctg
    33121 aagcaacaaa gtaacctttg tcaccaacct tctcacccca tgaattttca accttccatt
    33181 ttaatggttt tcctgtttca tctaagtcaa cacctgttaa aaccatagca tgtgtcatca
    33241 aactttcact ataatccaaa cgtccagcct tatcttgact aagattgata tccatactag
    33301 cttcaaaatc gtaagtatta gttgccaaaa tgcctttttg acgatctgaa acttgaccca
    33361 catcagagcc aaaccaaacg gactcaccag cctgcatctg cttgatagct agttctttga
    33421 aacgtttcat atcaaggttg aggtagcgaa cctcacgact accgaccaca tttcctagca
    33481 tctcaacagt gtatgatttg ccataaggct tatcagcagt tggcgcatta ataacagaca
    33541 cataatcaga aagctttaag ccaacaaatt tgtcgtaaaa cgcttgcggt gtcaaacctt
    33601 tctcaacatg atagtggtca tctttatcac ggtaggcaaa atcaaaatga cgaggtggta
    33661 aaccaagggt catggccaag aagttaaaaa tttcctgaag aagctctgct tttcgatcct
    33721 caacttggtc tgcattagca cctgacgcaa tcaggtcacg aagaatttga gcatcttggc
    33781 gcaataattt attcaaatac tggtttaatt cacgactgtt acttgatgag attgattctg
    33841 ggtaaacaga ttttggcacc actccatact tctcaaacaa ggaaaccacc atgtcccact
    33901 ggccaccatc ttgttgtgga acatccaaga gaaacttaac tttacgactg gttaattctt
    33961 ggtcagctgt agcaatgacc tgctccataa accagttagc tttttcatac ttatcccaaa
    34021 agaaagtatg agcttgtgac agttcaaaat tttctaattt aaactctgtg attaatttgt
    34081 gtcggaaagt gttcaaggca gcaaacatcc agcagcgacc agaagccttt tggttagata
    34141 ccttatcttt agttaaatca atagaaaaca caaaatcatt gtccacttca ctttgacggg
    34201 tttctaatga ttttagcaaa ccattatgcg taacggcatt ctcaatagct gaaaattttg
    34261 cattggcttc gtaatgagca aataattgtt ctgtaaatgt ctctgttaat gctgacatta
    34321 ttgtcctcct aaaatattaa gataagcttc acctgaaata atattggcaa gatggttatt
    34381 atccagccat tctattctaa aggattactt ctattataga ccttatttga ttttcttcaa
    34441 gaaaaaagtt aggataacct aacttttttt gttttctttt tttactcttt gaacatcatc
    34501 tcttatttcc aaaaatcatc aaaaatggtg attggcaggt gacgcttgtg ttgtccttta
    34561 tgccaccatt tttcaatagt tgcttgagct actttggaaa tcagcttccc ttccaaatag
    34621 tcgtcgatgt cttgataggt cacccctaga gcaacctcat cagccaagcc tggtttttga
    34681 tcttctaaat cagcagttgg aactttttca tacaaagcag catctgctcc taaaactttc
    34741 aaaagagcct ttccttgacg tttgttaagc ctaaagaggg gaagaatatc tgctccacca
    34801 tcaccaaatt tagtaaagaa accagtgatg ttttctgccg catgatccgt tccaataaca
    34861 gcaccagcca tttggccagc aatggcatat tgactgatca ttcgctgacg tgctttaata
    34921 ttacctttat tgaaatcaga aatctcgatg ccagcttctt gcaaggctgc tacttggcca
    34981 tcaacagctg ctttaatatt aatagtcagt gtttggtctg gcatgataaa agccaaggct
    35041 ttttgcgcat ctgcttcatc aacctgaacc ccataaggca agcgaacagc tataaattgg
    35101 taagcttgat tacctgtttc ctcccgtaac tctgcaatgg ccatctgggc tagctttcct
    35161 gcgagggtag aatcctgacc tcccgaaatg cctaagacat aagtttttaa aaatgagtgc
    35221 ttacgcaaat aagcttttaa aaaatcaacg gctttccgaa tttcttcttg tgggtcaatg
    35281 ctagccttga cgcctaattg tcggataatc tcttcttgta gtgtcatgtc attcactctt
    35341 tccataagca tctttgcgaa tgttatcaat taaggccatc ttgttttgcc acacatcacg
    35401 ggctaagtct actgggtagt cttgaggatt taagacacgc ttgtattcat cccaaagctt
    35461 gtcaaattct tttttagcat aagccttgat ttcagctaag gtcggtagct ggtaaactaa
    35521 ttctcccttg acaaaaatat caactaagag aggaattgca tcaaattctt taacggtttt
    35581 cttaatatag gtataggtcg gatggaacat ctcaatctca gttaattcat taacattaat
    35641 atcagtaaac gtgatatagt cgccttctga tttgcctttt tcacgactgg tgatgcgcca
    35701 aacttgtttt ttacctggtg tggatacttt ttctgcatta tttgataatt tgatcgtatc
    35761 acgcatgcta ccatcttctt gctcaataga gacaatctta taaacagcac ctaaggcagg
    35821 ctggtcatag gctgtgatca gtttggtccc aacaccccaa acatcaattt tggccttttg
    35881 catttttaag ttgaggatgg tattttcatc gaggtcatta gaagcataga tcttagcctc
    35941 ggtaaaacca gcgtcgtcta actgctgacg gactgttttt gagaggtaag ccaagtcacc
    36001 agagtccaat cgaacaccta gaaaattaat cttgtcaccc atttctttgg ctactcggat
    36061 agctgttggc acacctactt taagtgtgtc ataggtgtca acaagaaaca cacaatcttt
    36121 atgggtctta gcataagcca tgaaagcatc ataatcatta ccataggctt gcactaaagc
    36181 atgagcatgc gtacctgaaa cagggatacc aaagcgttta cctgctctca cattacttgt
    36241 tgcatctgct ccaccaataa tcgctgcgcg ggttccccaa atcgcagcat ctagttcctg
    36301 tgcacgacgg gtgccaaatt ccaaaagggg ttcatcctca atcacagaac gaatacgagc
    36361 agcctttgta gcaatcaagg tctggaagtt aacaatgttt aaaagagctg tttcgaccaa
    36421 ctgacactga cctagagggc cttctacttg cacaatcggc tcattagcaa aaaccaaatc
    36481 tccttcttta gctgaacgga tggtcaattc taatcgtaac tctttaaggt aggtcaaaaa
    36541 gttttctgga taacccagtt cttcaaggta agccaaatct gtttctgaaa attgaaactg
    36601 ctctaggtac tccaccatgc gctgtaaacc ggcaaaaaca gcataaccat tgttaaaagg
    36661 ttccttgcgg aaatagactt caaacaccgc atgacgatta tgaatgccct gctcaaaata
    36721 aacttgcatc atattaatct gatataaatc agtatggagt gttaaactat catctttata
    36781 cataaagggg actcctttga attattgtta ctattataac atattttaaa aaaggctctt
    36841 ggactagggt ttagaaataa cttgagttat cgctaaagta aaaaaagaac tgatccatca
    36901 tgacactctc aaataagaaa gagttaatgg attcagttct atatcgctaa ctattattta
    36961 aatttgacat tgctataaat cccaaaaaca ataatccaaa tcgttgctcc aatggcaccg
    37021 atataggtgg attcttgtaa gaaaagagag ataaagacaa aggcaaagaa agcaagggtc
    37081 aaaggcgttg tcactttata ttttggcatc aaataaccat ctgccataaa gtccttagat
    37141 tgacggtact tccagtgagc aatcatggtt aaggcgtaga tagcaatata tacacctgat
    37201 gaggaggccg taatgagtga gaacgcatct gcaactcctg gtaggatatt aatcaaagct
    37261 gagataccaa ccacaaccgc tgaagcaata atggcacgac ttggcacccc ttgtcgagat
    37321 aaagtattaa tctttaagcg attggtcaaa gcgtttggag tctcattagc aatctgatag
    37381 agatgacgac cggttgaata aagggttgag ttaagcgctg acgctgctga tgtcaagacc
    37441 acaaagttaa tcaaggctgc tgcccattta ataccaatca atttgaacac catcacaaaa
    37501 ggagattcat caactggtaa ctgatgccat ggcacaattg ccataataga gaccaaggct
    37561 cccacataaa agatcacaat acgggttgga atttcttgaa tagcctttgg tagaactttt
    37621 cttgggttag ccgtctcaga agtggtaatt cccacaaatt cgatagcttg ataagcaaag
    37681 aaaaccattt ggaaggccat aaagaacttt agtttcccat ttgggaacat ggaaaaatgg
    37741 tcaaaaatat tggaaaggct agcatggcct gtgtgagttt caaaacctgt caataccatg
    37801 aaaatagctg ttgcaatcaa agctaaaata gctaaaatct taatcatggc aaaccaaaac
    37861 tctgtttccc caaaaacgcg cacagcaatt aagttgatcg aactaagtaa gactaagaaa
    37921 accaactgaa tcaaccaggc tggccagctt gggaaccaaa attgcacata agcacctact
    37981 gctgtgattt ctgccattcc aataaaaata agggaaatcc aataggatag acccgaaaaa
    38041 taaccccagc ctggaccaat gtatttggaa ataaaattga taaaggtgtg ttgatctgga
    38101 tcataataga gcatttcacc gatggcacgc atcatcataa acatgaaggc acctgtaatc
    38161 atatacacaa aaataataga tggtcctgtt aaggcaatag agcgtcctgc ccctaaaaag
    38221 agacctgttc caatcgttcc tgcaatcgca attaactgca catgacgatt ttctaagccc
    38281 cttaccattc cattttctag ttcgttattg tctgtttgtt cttttataga cattctaaac
    38341 tccattcact aaaatactat ttattatatc cttttttcag aaaattttca acatttatct
    38401 aggaaagata ttaaggaaaa ctgttcttta tatttcttaa aggtcttatg caatttagct
    38461 tttttaaggg aaagacaagg aaaaatgaag gagttttaac cttatgaagg gaaactttca
    38521 aggtagtgat aaacaccttg ccctgcaatt gcaccatctc caacagctgt cgtgatttgg
    38581 cgaaggtctt tttgacgaac atctccaatc gcaaaaatac caggaatact tgtcctcata
    38641 tgatcatctg tgataatcca accttctgaa tcggtaattt ctagattctt taccatacct
    38701 gtaacaggat tcataccaac atagataaac acacctccaa aagcgtggtc agtgacttgg
    38761 cctgttttca cattttcgat taggacattg gagaccttaa tgtcgttacc tttgatttct
    38821 ttgacaactg aatcccagat aaagtcgact ttgtcattag cgaaggcacg gtcctgcaag
    38881 attttctgag ctcttagttg atcacggcga tgaacaacgg ttaccttttt agcaaactga
    38941 gtaagataaa tagcttcttc aactgctgag tcaccaccac caacgaccaa aagatcctgg
    39001 ccacggaaaa acgcaccatc acatactgca caataagaaa ctcctcgact agtatagtat
    39061 tcttcacctg gaacacctag tacacggtat ttagctcccg ttgcaataat aaccgtttta
    39121 gcttcataac tagcatcttc agtcagcaca cacttatagt caccaaaatt ttctattttt
    39181 tgaacaatac cataaatgtt ttcaacgtta aacttctcta aaggttcgta cattttcata
    39241 gctaattctg gtccagatat atgatcatat cccgggtaat tctctatatc aaaagtgttg
    39301 ttcatctgac caccaggtgc cccttgttca ataatagcaa cagataaatt acttctagca
    39361 gcgtataaag cggcagtcat tcctgctggt cctgaaccaa taattaatgt atcgtacatg
    39421 atttttctcc tttaatctac tcttgccaat attttagcaa tgataatccc ttcttgcaat
    39481 gattaggatt ttatgacaac caaaatactc ataaaagcaa acgataaaat tgggatggtt
    39541 aaaatagcaa ccattagcat ctcataaaga aaagcttgtc tttcaatcaa tgttttatct
    39601 cttttggttt ttgctcgcca taaagtccat attaaacaaa ttaacatcat agtaaggctt
    39661 gagagaatga gaccttttac ataaaggcta aagatttcta ctaacatatt tccacctagt
    39721 cattatttct ttcccataag tttttctaaa aaacataaca agaaaagccc agggatacct
    39781 agaccttttt attataacaa aagaataaca ttaaatgtat gtttttgaat agcttgcaaa
    39841 aaattctttg gttcgttctt tttgaggatg tctaaagact tcttcaggtg ttccttgttc
    39901 caagattttc ccttgatcta aaaagagtac tctatctgcc acttggtaaa caaaattcat
    39961 atcgtgactc actaaaacca tggtctgtcc ggatttagca gcatcagtaa tagacttttc
    40021 cacttcgcca actaattccg ggtcaagagc cgaggtcggc tcatctagta ataaaacatc
    40081 tggtttcata gccagagctc ttgctaaagc tacccgttgt ttttgtcccc ctgataaatg
    40141 acgtgggtaa tgatgttttc gatctgctaa accaacctta gccaattctg cttgcgccag
    40201 tttagtcgct tcttggtcag acagtttttt gaccacctta agaccttctt tgacattctc
    40261 aagggctgta cgacgctcaa aaagattaaa ttgttgaaaa accatggcaa gtttccgacg
    40321 taaaataagg acttgctctg tggtaatggt ctcaaaatca accgtaaagt caccaatgct
    40381 aatggagcct gaatctggtt tttccaaata gtttaggcta cgaaggaaag tcgatttccc
    40441 tgctcctgaa gcaccaacta aagcaatcac ttgacctttt tcaatatcaa gagccaaact
    40501 atctaaaact ttttgccctg agaatgtctt gctcaaattt ctaattgtaa tcatcaacgc
    40561 aattctccta acttttcatt tctagcttgt tctggtgctt tgatggccat cttgttttca
    40621 atcaagcgac ctacttgctc catcaaaata ctgatagacc aatagacaag agcaacagag
    40681 atataacgtt caaaataacg gtaatctgat ccgcctagaa tttgagcctg ggcaaacatt
    40741 tcgacaatcc ctgcattaaa ggcaagcgat gttcctttag ttaagccaat taacccatta
    40801 atcaaggttg gaatagccac aacagttgca ttaggaataa tgacacgacg gtaaacctgc
    40861 acagaagtca tgcctagact ttttgctgct tcaatttcac ctgtatctac tgataaaatg
    40921 gctgcccgaa tagtttcact agcgtaggct gcttcattaa aagcaaaggc tgtaatggca
    40981 aaaatagaag ccggaattgc attaacattc caatcaaagc catacttctg attgagaaat
    41041 tttagaaaga ggggaatacc gtagtaggtc aacatcaact gtaccaaaat aggagttcct
    41101 cgcaagaaac tcacaaaaat agcttgaata gggtatagta gcttcacttt attaattttg
    41161 acaagggcaa aaatcaaagc caaaaccaag ccaaaggttg ctcctgatag tgtcaaacca
    41221 agcgtaattg gaagccgttg gataatattt ggaatggcat caaaaacagc atgccaacta
    41281 aaaagtttcc catgtggaat cggtgagatg aggtaatcat aaaaagccca accactggtt
    41341 aaaaacactg atgtcatgta tttccccttt gtatttgttt gtcttaatat tctaacactc
    41401 ttagacccac atgtaaaata gtaaatccgt attatagcaa taagcaaaag ctatgatcac
    41461 tttttgtgtt aacaaatggt aaacaataca agtagcaggt gtaaaaaaag caagattaga
    41521 tgccaattga tcacttgctt gctctttgtt cttaaaaatg ttgttttttg gccttacgct
    41581 cagcgcggcc cttagcacga ttttcagcac gacgttcttt gcgacgtttt tcatcaaccg
    41641 cccactgaat ttttttcttg taacctggtt tgactttttt ctttttcttt ttgaccaaac
    41701 caatcatttc tgtgtctaat ttttgatagg ctttttcacg gttttgacgg cgatcacggt
    41761 cataggtatc ttgaaattct ccatttttga gcaccttcgg tgtaaaggca atccccattt
    41821 tttccagctc tttgatatct gagtcgtcac ttggctggta aagtgtaatg gcagttcctg
    41881 ccataccatt tcgacctgtt cggcctacac gatggacaaa gaaagacaag tcttgtggga
    41941 tggcgtcatt gatcacatgg ctgacccctt caatgtcaat cccacgcgct gctaagtctg
    42001 tggcaacaat gtattcaaag tccagttttt tgacttggtt catgatgcgc ttacgttctc
    42061 ttggaggaat gcccccatga atcttagcca cttttaagcc attagctgtt aaaaaggcat
    42121 gcaaatcatc tgcgcgttcc ttggtattga caaaaagcat agccatataa ggctgcatag
    42181 ttttgagaat ttctaacagt tgaccattct tatcacgccc ttttgtcgac acaagccagt
    42241 tatcaatggt atctgcgata acggtctttg tcttgatttg ttcaataaca ggattggtca
    42301 agtatttttt caaaaagggt tgtaatttct gtgggatagt tgctgagaac accaaaatct
    42361 gaacagattt tggaagcgaa gctgcaatct tatctaccgt atccaaaaag cccatgtcca
    42421 tggtcatatc ggcctcatcc acaacaaagg tcgttgcttt atgaatcgct aaatcaccag
    42481 acttgaccaa gtcataaata cgacctgggg tcccgatgac aatatgcggc tggctgcctt
    42541 ttagtttttc aatctgacgg agtttgtctg tgcctccaac atagttggcc aaacgaatct
    42601 cttcttggaa gtgcttagca atctgtttac aagcatcaaa aatttgagtt gctaattcac
    42661 ggctaggtgc tgtaataacg acttgcactt ctgctttagc ttcatcaagt ttttcaaaaa
    42721 tgggcaacaa aaaggtgtgg gttttccctg aacctgtttt tgattcccca actaagtcac
    42781 gaccggagtt aacaatagga atcagccgct tctggacctc tgttggattg acaaaaccaa
    42841 tttcttccag tgcttgctgg atatattgct taaaatgata atctttaaat gacatgtttt
    42901 acctcgtttt cttccatatt atatcattat tgttagagac aagcaaaagg agtgggacaa
    42961 cactcacaaa atcagcattt gtgggtcatc tccactctct tattgatgat gttaatcaaa
    43021 atgctattgg tgactattct tgataatccc ccttagaaga cgtataagat agctaaaact
    43081 agtaaactag ctagacttcc tactccccac aaaaaagcat ctacctgcca ttctgaccac
    43141 ttcttgcctt taccagacaa gcctcccaat tccaaatggt ggtggaaagg cgtcattcta
    43201 aaaatacgac gaccttctcc atattttttc ttggtgtact tgaaatagga cacttgcaac
    43261 atcacagaac ttgtttcaag aacataaacg atcccaataa tcaggagagt ccattcttga
    43321 cgaagcgcaa tagaaatggc agccaacata gctccaaggg ctaaactacc tacatctccc
    43381 ataaatactt tagcaggttt gtgattaaag cagaagaagc caagcaaggc tccaatcatt
    43441 gctccaatca gtaacaaaac atcaaattga ctctgaacgt aggcaataac accgtaagtc
    43501 actaaactaa tcaccactga gatagaagct aagccatcga taccatctgt caaattaacg
    43561 gcatttgaaa aaccaaccac ccaaaacaaa acaaagaata ggtagaaaat tcccagcggc
    43621 agctgataac caaacacatt aatagaggaa atgccacttg gactaacatg taaaaaatag
    43681 aacatcaatc ctccaaccaa ctgcaaggct aacttttgtt tggctgtcaa tccttcattg
    43741 atttgcttaa aaatttttaa aaaatcatcc aaaaatccga taatcccgta aatgacaaca
    43801 attgataaaa tgcctgaaat caaagctaaa ctttgagtgt ttttgatcga aaatagacta
    43861 accaataacg atactgccgt agctactaaa agaaaaacag ttccccccat agtcggtgtt
    43921 ccagctttag ctaaatgttg cttgacatct tcatgcattt gttgcccacc aatttttttc
    43981 aattgataga atttgataaa ataaggcatt gtgaaagcag ataccataaa ggatatgatt
    44041 gctgcaataa gggttaaaaa catgttaatc tcctaaagta atggtcattt tttttatttt
    44101 tttcaaggat ttaccaacat caacactttg tttcataaca cgaccagaat ctgttccttt
    44161 aaagctgatg tctattccag tccatttagc aaaggtttta acattggatt ttgtccagcc
    44221 atacatgtct ggtacctcca caaaacggtc tgataatatg agaacttgtt ggttttctgt
    44281 taacgtttga ccgggctgat gcgatacttt tttgatcttg ctgccagtac caaggacaac
    44341 tggctggaca agatttcgac gcaactcgct tgatgtctca ccaggattct ttcctacaaa
    44401 gtttggtaat ttataagttg tttgacgatt agcatctgat actactggct tagttagtgt
    44461 atcttgcatt aagtatgctt cttccaatac tgggttaacc acatcttgcc aaaaaagggg
    44521 accaaaatgt tgtggtttag tcatagtaac atacatcaaa aagtccggtt tatcagctgg
    44581 caccattgcc acaaccgaat agacatagtt agtcaatcca ccatcttgat aaccacttcc
    44641 atcttctgaa ccaatttgtg ctgttcctga tttaacagca acaggtaaat cacccacttt
    44701 aataattggt ccaaatgttt ttgaatagag tgttccaaac tcagggtctg ttcctacacc
    44761 aatcatgtat tgtcttgttt cactagcggc tttttttgat acaggttttc caacaatttc
    44821 tttatttgcc gttctaaaac ttgctgtgtt aggatcataa atttgactga taaattgtgg
    44881 ctctaacatc tcaccattat tagaaatagc agtaaaggct ctaagcattt gaatctgggt
    44941 tacagaaatc ccttgaccaa aagcgctcat agcttgagtc acgatattat cagaaggaaa
    45001 tatacctgcg tcttcatctt ttaaaccaaa acgagtagga aaaccaaagc ggaacttcgt
    45061 caaataattc atccattttg cattacccat tttttgttca agtttagtca tcccaacgtt
    45121 acttgagaag gcaaaccctt gtgcataatt catgtactgt cctgtggaaa tgccttcgtt
    45181 aatagaccag tcttgaatag tagcatctgc aattgttaaa ccattagcat tgctaaaggt
    45241 ttcgtttggg ttgaaaactt tatcatcaat agccgctgcc agagtcatca ctttcatggt
    45301 tgagcctggc tcaaaatttc cttgatgaag tgcactgtac catttgtagt tcgtattttc
    45361 aagtcctttc agagtatcag cattataagt ggggcgttgt gttgttgcca aaatttcacc
    45421 agttttagca ttaacaagtg ttgcactggc caactgacca tttgatttgg cttgaaaaac
    45481 atccatctgg gtttctaaga aggtctggat aggctcagat agcgttgtgt aaatatcttt
    45541 gccatcaata gctttcttga cagtcttacc tgtacccaag agtgtggtcc catttcgatc
    45601 tttttgataa gtaataacac catcttgacc tgataaaatt ttatcaaaag aagcttctaa
    45661 acctgttttt ccaactaaac tcttaacacc tgtcttttta tcttctgtta gagatgctag
    45721 gcctataaat tctgaagcaa atgtcccatt tggatacata cgaccaggac tagttgtgaa
    45781 agcaattccc ttgattttgg catcttccat agccttttga atagtagaca tagtactata
    45841 tgaaatgcca gaccctgacg gtccaaacga gacttggaaa agtcctttac gcttaagctg
    45901 tttaattaca tctgtttttt tcattcccag atgctttttt aaaatatcag ctactgtttc
    45961 atactgagaa ggttgtacat ataacttttc atctgaagcc gagacaaatg atttatccaa
    46021 aattgcgtat atgctataag tcgtagaatc cactgcaata gctgtaccat ttcgatcata
    46081 aatggtccca cgcttagctt ggatcgtaac ggtttcttga taaaccttct tcgccccttc
    46141 tgacaaacta actccaaact tttgatctgt tccaataata atcatgaaat taataatgaa
    46201 aataaagaaa ataaagatag ttaagagcat catattttgt ccaactcgaa cgcgattttc
    46261 gactggagtt ctcctatcgc gcacaacata atctaaaaca tatttttgcc attttttcat
    46321 agattactcg actttcttga tattattatt acggttgctt aagcctgctt taccagcaat
    46381 atctataata cgatcacggc gagataactc atttacttct tgcttggcat tattaagctc
    46441 tagtttttga tccgaaatat gactatttaa actagtgatt tcttgttgta gctgcaactt
    46501 acgactttgc aggtaaataa tacttactgc catcgtaatc gctgttacaa tgatagcagt
    46561 ataaaaagcc ttctcaattc tagagaaagt ttttattcgt ttttgcaagg catttgtaac
    46621 tgcctgagtt cttttttcat ttgtcatagg cttatttccg aatttttttg gcaacacgta
    46681 gcttggctga gtgtgccctt ttattagctg ttaactctga atgactaggt aagatcggct
    46741 tacgtgaaac aagttcaaac ttaggtttca tatcttcagg aattagagga agcccttttg
    46801 gcacatccac cgtactagct tctttaaaca actgcttggt taggcgatct tccagagaat
    46861 ggaaggtaat aactgagata cgaccatcaa gggctaataa ttccatagcg tcctgaatag
    46921 attcatcggc cgctcccaat tcatcattga cttcaatgcg aatagcttga aaaatctgtt
    46981 tagcagggtg gccttttttc ttcaactctt tagctggctt tgctgcctta atcaattctg
    47041 ccaactctgt tgttgtctca ataggcttaa tagctcttgc ttgttcaatt tttcgagcga
    47101 tctgcttgga gaatttatct tcaccatatt tgaaaaaaat cttaaccaaa tcattgaatg
    47161 gataggtatt caccacttcg taagctgtta agagcgactg acgatccatg cgcatatcca
    47221 atggagcatc ttgtttataa gaaaaccctc gttctctttc atccaattgc gggctggaaa
    47281 caccaaggtc gtataagata ccatcaattt catcaactcc aagcgctgtt aaacgtgctt
    47341 tgaggtgtct aaaattatct ttaataaaag ttacctgtcc tttgtcaata taagatttga
    47401 gggtaacttg tgcattgtca atagcctttt ggtcttggtc aaaacaatag aggtgccctt
    47461 cttcaccaag tttggacaac aaataagctg agtggcctga gccacctagc gtcgcatcaa
    47521 cataaatccc atcaggcttt atgtcaagca tgtccactgt ttcgtgaagg agtacggtca
    47581 cgtgatgaaa ttcttttgtc ataactttaa ttgtaccata cttcaaaagg tttagaaatg
    47641 aaaaagtaag agaaaaggat ttcattctcg tgggaatctt cctcttctct aatcttgttc
    47701 tttttgttcg ctatcagcca acttagcaag cactgactta gccgctgcct ctagaatttc
    47761 aactgcttgt aaaaaatttt tagcttcttt aatcacacaa caatctgtca gcaggttgtc
    47821 taaccaaata ccaaaggttt tatcccaaat cgtatttggt aagtcagcta ataatagcct
    47881 atcgacgtct gccagctatc ttcggcagtt ttgaagagta acttgtaagt ctattaataa
    47941 ttggttgacc ttgctcacga cgtttgatcc agctgacaag cataccatct ccaaaaaaac
    48001 aaaatagccc caatttcgga caattttcaa ttccaaatga atcacctgaa tctgatgtaa
    48061 aagttcttct aaagcaacct ttgcttcttc tttttctctt tcattagtca ttaagggacc
    48121 ttctagtagc ttattctctg atatgtccat ccccattaat ataaaattta gtgctggtca
    48181 aggcttctaa gcccattggc ccacgggcgt gcattttttg agtagaaatc ccaatttcag
    48241 caccaagccc aaaaacaaaa ccatcggtaa atcgtgttga agcgttgaca taaacagcag
    48301 cagcatccac taaatcttga aaggtctctg ctgccttaat attccttgtg atgatagctt
    48361 cggaatggtg actagtatgc tgatttatcc aagaaatagc ttcttccaaa gtggaaacaa
    48421 ccttaacaga catgatataa tctaaaaatt cggtctcaaa atcctctgct tttgcaggca
    48481 ctgcctgctc aaataacggc aaagccttgt catctgcccg ccattctact ggctgaacct
    48541 gattgatcgc tttttcaagc ataggaataa accttgctgc tacagcttcg tgaattacca
    48601 atccctcagc tgcattgcaa acacttgggc gctttgtttt agcgttgata acaatcttag
    48661 tagccatatc taagtcagct tgagcatcca catagatatg cacattcccc acacctgttt
    48721 cgatgacagg cacttttgct ttttccttaa cggtctgaat taatttagca ccaccacgtg
    48781 gaatcaaaac atctacataa tccgttgcct gcatcaattc ttcagcgaca gcatgtgagg
    48841 ggtcctcaac tagctggaca gcatctgggg tgatccctga tttttccaga ctttgtcgga
    48901 tcaacttcac caaagcttta tttgagtgaa aggcatcttt tcctcccctt aggatgatgg
    48961 cattattggt tttgaacgcc agactaaaag catccactgc aacattcggg cgactctcaa
    49021 aaatcatcgc aatcacccct agaggaactc tcttttggag gattttaaga ccatcgaggt
    49081 tagtatagcc cttaatgact tgtccgattg gatcagctaa gtcagcaacc tgttgaactc
    49141 cctgtgccat cgctttaatc cgttctgaag ttaagcgcaa gcgatccatc atgatgtcag
    49201 aaataccatg ttctttagca ttcgctaaat ctttttggtt agcggctaag agagtctgtg
    49261 tatcgtcaac taatgccttt gctaaggtgc ttaaaaagcg atttttaatt tgcgtcgaca
    49321 aaggtgctat taaaagacta gcttgttttg ccctttggcc taaccttctc atatcagtca
    49381 tgtgttacct cttctatctg cttgaaccag gtgcctagtg gttgcccttc aagcactctt
    49441 aaaatatctc tgggattagc tccattcatc aagaccatct gtcctttgtt ttcaaatacc
    49501 atctgagcag actgaatttt gctaagcatc ccacctgtgc caaacttact gcccgcacca
    49561 cctgctgacg caatgatttc ttgcgtaata ttagcaacat ggctgcgtag ctgcgcatcc
    49621 tcataaatag tagggttttt atcaaaaagg ccatcaatat cagacaacat gattaataaa
    49681 tcagcttttg taataccagc aacaacagca gataaacggt cattatctcc aaatttagtc
    49741 gcatgatcca tttcatccac actaaccgca tcgttttcat taacaatcgg cacaatgccc
    49801 aaactaatca gactttcaaa agcattggta acattggcta gactttctgg gaaaaccacc
    49861 acatctctcg tcaataaaat ttgtgacacg ttggtttggt agtgtgcaaa aatttgtgaa
    49921 taaagactca tcatggctac ctgaccaaca ctggaaactg cctgttgttt agcaagattg
    49981 gtcggacgtt tttccatttt caaaatatct agtccaaatc ccatcgctcc cgatgatact
    50041 aaaataactt ccttgccctt attcatcaaa cttgaaatca caaaagccag ttggtcgatt
    50101 ttttctaaat tgattttacc tgttggtagc actaatgaac tagtgccaat tttaattacg
    50161 atacgtgtta catcttcaaa ttgtcgtttc atcataccca aattatagca taaaaaacag
    50221 ccccagagga ctgtttttcc gaataatgat ccctcttcgt taaagcctct ctaagctttt
    50281 ccagaaggtt ttttgaatcc ataattgcgc aagacctaaa accattagta ttagacaact
    50341 caatagaata ctaatcaaca gaggttgttg gataatattg gcaatgataa cagctccaaa
    50401 acctagcaca cctgcaacta ttaaattacc aaagataagt cccattgtta accattgccc
    50461 atctcctctg gtaaagagtt gcgtcatgtc ttgccatttt aaatccagaa gccggtagtc
    50521 acgacgatac atcaattccc cttgcacaat cagtgatagg gcgtagccaa gacaaaaagc
    50581 aagggttaga agaggatgca ggtgcaacac aaagagacca aacacaagat aaatcaccat
    50641 aggcacaatc agttgcagac ctacaagcaa gcaaaattta tccagcaaga atttttttaa
    50701 cgttattggt aagcttttaa taaaggtaaa gttatccttt tcaagtgaaa tacctactcc
    50761 aataaagctg gttggtgttg cacacatgat acccaaactg accccaaata ataaggccac
    50821 cccaaagtaa tctggggaaa tatgcttaaa gaaacctgtg ccacgtgaca aacttggacc
    50881 gataaaaagc atcacataca tcaggggcat gagataggtt tgtgtcagta aagttgcatt
    50941 ttgtaacgtt aaaaggtgat gttttcgcaa caactgcgcc agtgattgat tctgatgagg
    51001 acgattaact ggttttttag tttgcttggc tttgttctcg ttactaatat aaaaagcctc
    51061 acgataataa gttggcatca cttttgtgac aataccatat accatagcta gaataagtaa
    51121 caatggcaac caaaagttaa ggagggccgc agtagcaaac ggtgcctgaa caacatcata
    51181 gaatcctttg aaatagggaa tagttgggta atcagtaaat acgccatcca tcatcgtacg
    51241 cttgttgtta ctaatattaa tcgcaaaaat taagacgaaa gcgccaaaag ttgagacaaa
    51301 catcatgata gttgaaatga gttttcgttt gcgacttctt acaatgattt tgcctaccca
    51361 agcattgata taaatagcta ataccataga actcactagt aacactaaaa agagcacgat
    51421 agctactaaa atagacaaag gatttcccaa gagttgccaa taggcaatta agagaagaga
    51481 gataagaggc atcaaaaaga cagcacccat ccctagcgac gagacaattt ttgcaatata
    51541 gagttcttct gacgttactg gtaagtgaat ataaagtttt aggtcattac tttcataaaa
    51601 aatggtgtaa agagagctaa aggctgtcaa ggttgacatg ataaaaaaca tagcaacgtc
    51661 aaaggagaaa agtcctggat aatgactgaa atcaacacca ataaacataa aaaggtaaat
    51721 caccaaaaac atggcaatca ttaaggcctg ttgcctcatc atgcttttat aggctttgaa
    51781 gttttctttc gggtgttttt cctgacgctt tttgaggtta gctaaacttt gtggattgga
    51841 ataaagaatg tttatcttga taagttccca aatagtagac caattcatgc catcacccct
    51901 cttcttgcgc cttacgccca gcgagttcaa ggtagatgct ctccaagtct ttgtcaggat
    51961 ggtgttcttt caactcatca atcgttccaa caaaaatcaa tttccctttt tttagaatcc
    52021 cgatacgatc acataactgc tcagcgactg atagcacgtg agtcgaaaat aagaccgtat
    52081 gtccagaagc tgcatgagct ttcatcattt ccttaaggtc aaaagaagcc tgaggatcca
    52141 aacctgttaa tggttcatcc aaaatccaga tgttaggatt tgatacaaga gcaccaatca
    52201 caatcacttt ttggcgcatc ccatgtgaga aactatcaat ggtttgatta acttcttctt
    52261 tcagttcaaa aagtgttgtc agctgtgcta accgttcttc tcggtcctca tctgacaccc
    52321 cataaatttt agctaaaaac tgccaatact catttggagt tagattcaag aaaatatcag
    52381 gagaatctgg cacataagca atttgttttt tgatagcttc tctattttct gtcagaagtt
    52441 gaccatccac aaatacttcg ccataactcg cttcgataat agaagtcaaa atgctgatgg
    52501 tcgtggtttt acctgcacca ttatgtccga taaggccaaa aatttcaccg tcattgatgg
    52561 tgacgtttaa atcgctgaga gcttctttgt cgccatacaa ctttgaaaca tgtttaaatt
    52621 ctatcatggt atcctttttc cttttcttct ctttttctcc ctagaccgat gaggcttcct
    52681 ctaaaatata cttttccaat gactgcttaa aacggcaaag cgattttgga agtaaaatgt
    52741 cattatcaag taagtaatta tccacatctt ggtttagttg gtaggcaaca agaagtgggt
    52801 tactgtgttt aattaatcta ttagaagctg ctaaaagtag ctgcgacaag gccacatttt
    52861 cacggttttc tggataatca taagcctgtc taatcacatc gtataagcgc tgtcgtttct
    52921 tttccattta tactccttta ttttttgtac ttttacgcta atacaataac aattaaatta
    52981 taatttttat gaatcgtttt gtcaatgact tcttatcaaa agaagtgtat taggcagttt
    53041 gaggaaaaga aagaactggg tattttattt taaaaaaaca gagtaaatca aatgatttac
    53101 tctgtttggg atgtttaact tagagtgatt tgtataactc agttgcattt gccacagtga
    53161 aaccatattc ttcgaagata cgatttcctg gagctgaagc accccaagtg tcaatggtca
    53221 atgtttttcc tgataggccg acatattttg cccagccaaa gcttgaacct gcttcgatag
    53281 cgagacgttt agtcacagct gctggtagga tgctttcttt atactctgct gactgttcgt
    53341 caaagatatt ttgtgatggc atagatacga cacgcacatg aatgccttct gcttcaagag
    53401 cttcttgagt atccattgcc agtttcactt ctgaacctgt tgcaatcaag ataccatcaa
    53461 ggtcgccttt ggcttctgat aaaatgtaag ctcctttgtt aagaccatct tctgccaatt
    53521 cttttgtgcc ctcaagcact ggaaggtttt gacgcgtcaa tacaagcatg gttgggcgat
    53581 ctgtttcagc aatggcacgt ttccaagcag catttgtttc gttaccgtct gctggacgaa
    53641 taacgttcaa gttaggcatt gagcgaacac ttgccaattg ttcaattggt tcgtgcgttg
    53701 gcccatcttc accgacagcg atagaatcat gtgtcatgac ataaactgtt ggcaagtttt
    53761 ggagcgctgc catacgaaca gctggaagaa gatagtttga gaagacaaag aaggtcccgc
    53821 cgtaaacgcg tgtcccgccg tgaagggcaa taccgttcat ggctgcagcc atggcaaatt
    53881 cacgaacgcc aaaccagatg ttacggcctt cgtagtgacc tggttggaaa tctgtttcag
    53941 ccttaaccat agtattgttt gaagctgaaa ggtctgctga cccaccccag aaagaggcta
    54001 cttgttctga aatttgttgg atggcttgtt gactggatac acgactcgcc attgaactac
    54061 caagttcgtg cgcttcaagt tctacttgag cagcttcgtt agtaaaggct ttttggtatt
    54121 ctgctgctaa ttctggatat tctgcttcat aagctgcaaa caagtcattc caggcttgtt
    54181 ctgctttttc accacgcgct tgaagacctt gagcaaagcg ctctgttact tcagcaggca
    54241 cttcaaaatc ttgatgagtc cattggtaag cttttttggc aaaagcaatg ccttctgctc
    54301 caagaggagc gccgtgaaca gctgaagttc cttgtttttc ggcaccaaaa ccaataatgg
    54361 ttttgacttc gatgatggtt ggtttctcag tttcagcttt agctgcttca atagcagctg
    54421 caatttcttc taaatcattt ccatctttca caaggatatg ttgccaaccg taagcttcga
    54481 aacgtccttt cacatcttct gtgaaagcca tagaggttgg accatcaaga gagatgtcgt
    54541 ttgaatcata tagcaagacc aatttcccaa gttttaaatg tcctgccata cttgctgctt
    54601 cttggctgac cccttccata aggtcaccgt caccattcaa agcaaatgtg tagtgatcaa
    54661 cgatgtcaaa gcctggtttg ttaaatttag ctgctagatg agcttctgcc atggccatac
    54721 caacggcatt tgcgatccct tgaccaagag gtcctgtggt tgcttcgaca ccgtctgtgt
    54781 gattcacttc tgggtgacct ggtgttttag aaccccattg acggaagttc tttaaatctt
    54841 ctacagataa atcataacca gctaagtgta acaagctata aagcatggca cttccatgac
    54901 ctgctgatag gataaaacgg tctctgtttg accaattacg gcttgttttg ggattaatgt
    54961 tcatgaagtg attccaaaga acataggcca taggtgctgc ccccattgga agtcctgggt
    55021 gtccagaatt tgccgcttga atggcatcca ttgatagggt gcggacagtg tttactgcca
    55081 actggtcaat tgcatcaaat gtcataagta aaacctctct gtttattaca actaaaatta
    55141 aacgttttct attgtctatt gtatcacaaa aatagacgct tttttcagaa aatcctccaa
    55201 agtccctaaa ttctttttcc ctattttgcc agaaaaaaac tagtttggac atcattggtg
    55261 aattcttttt gacgatgaat ataagagagc ctgttgacac agtagccaca gactctttag
    55321 ccttattttt taaaggaagc ccaatcttcc ataaaggttt tcaaaccatt tgtcgttaag
    55381 ggatgttgcg tcatcttagc aaacaagggg tctggaatcg tcgcaatgtg tgcgcctaat
    55441 ttagcaacag cttccacatg ggctgttgta cgaatacttg ctgcgatgat ttctgcttgg
    55501 aaatcgtaca agtcaatgat ttcacgaagg tcgctgatta attgataagc atctgtgcca
    55561 atatcttcca aacgaccgat aaatgggcta atgtaagttg cgcctgcttt cattgccatt
    55621 aaaccttggc ttactgtgaa aatcaaggtc acattagttt taatcccttc ttttgaaaga
    55681 atgtttgttg cttttaaccc ttctgtggtc attggaattt taacgacgac attgtcatgc
    55741 cacttagcaa tgcttctagc ttcttctacc atagcatctg ctgttaatcc tgtcacttca
    55801 gcactgattg gaccatcgac gatgtcacag atttctttga taactgtttc aaaatcacgt
    55861 ccttcacgtg agataatggt tggattggtg gtgacaccat ctacaacgcc aagttcatta
    55921 atcgctttaa tagcggctac attagctgta tctaggaaaa atttcatttc ttacctccaa
    55981 aaattttcga ttttgttaag ctctatttga taagcttttt caaatcatct acctttagac
    56041 tatcctactt tattattata aaagtgtaac agtccttaga aaagaccaag tatcacacag
    56101 ttttgtgtgc aaaactagac ttagctgctg ggctgagtga gagttcctct tctcgtgtat
    56161 ttttttgctg gaaaaggtct ttgagaaaag cttctaaagc agtgagttca tagggggagc
    56221 tatactgttt taaccggtaa tagggtaaat cttgtctcgg taaacagaca gtctgatagg
    56281 taatcagaca atcataaact ttctgatgat catagggcat taattgaaaa tccctacgat
    56341 gccccaaatg acgtctaatg gccaattccg caatggctgc ttccacctta ttttgcccca
    56401 aggcaagccc tactaaaaga ggctcatggt ggcgctcaat ggaaaaaatc aacaatgcta
    56461 aaatgtcgtc actcaactgc tgactgaaat ccgtttcctg atccatttgc agcactaaat
    56521 ggtttatgat aacccttaaa agcgctcttt tatcttcgcc tactaattga taaaggtatt
    56581 ggctattggt tggttgacta aggatagctc ctttaaaaaa gtaagctttg gaaaaaaata
    56641 tccccaagcc ataaatgatt tcctcctttg tctgatggat aatcacatga gccttcttta
    56701 aaagccataa ggcttctgaa atgtgatcag caataggacc tccaaaaccc aaactatact
    56761 tcatgctggc aataggaagt agaggataag catgcaaaaa gacaaagagg ctcttagctt
    56821 caaaagcatc aaattcaagg gcatagcgtc ttaagtaatg taaaagcatg ctttctaagc
    56881 gcttaaagaa aatattagat gtcataaagt cactatctct taaaaaatga tcattgtagc
    56941 ctttttgaaa ggacattcgc gcttgcgaaa tcgccaacca aatcaataat tgttctaagg
    57001 cttctgccga taatgactgg ccaatcagcc gctcaattaa ggtagccaaa tgcgaagcgt
    57061 ctaactgatt gaccaaggcg tctatacctt gtctggttaa ggtatggcgg aacaattcaa
    57121 aatagaaata acgccactga agctcacttc ccagttgtct gccttgcgag agcgccagat
    57181 caaattctga taaaagctgg ttgaggtgag ctagttgtct gtttagagta gcttcactaa
    57241 ccatcagttc aacggataag ttggtgatgt taaagtgttc atggcagtac atgtaggtca
    57301 atatctgata ggcaaccgat tctttgagaa gcagagctac caaatcctcc caatggaact
    57361 ggccattttc ttttaagctc agactgtctt tttctaaaag taattgacag gctaaacctt
    57421 gttctcgaca caaatgattt agattgtcaa tgtattttaa tagggtcact ttagacaagt
    57481 ttgatagcct cattaggtct tttagcctta acgtttcttt agcatgataa agggtcacca
    57541 agagacgata ttgggccctt cgttccttat ccattaagtc ttcaatcttc atggcggagc
    57601 ctcttttcaa ataatttgag acaagcttca tgaagatgat aagccaaatc actgtgacct
    57661 tgtaaaaaga gaaaatcttg aaatgctaag tcaccgtctg taactttcag agccagagcc
    57721 tgacctaatt gattggcgat gacaagagca ttggttttgg ataggagctg agcgcctatt
    57781 aaaatcccat ccatttttct agctattaat ttcagccaaa agaggttttt agaatcccca
    57841 ttttggtaca aatagctaca cgtatccata taaagctctg cttcttcttc tgtcacacca
    57901 acactcgcgc gataataacc aaagtgagaa cttcctaata ccttgaccgt ctgtaatgga
    57961 ggaataggat atccagctaa atgcagagcc agagcctgac ctgtcttcat tgcttggtta
    58021 atcaaaggtg tatagtaatc cattcccaat ataccaaaat gcaatgaaac catgtctcca
    58081 atggcataga tattagcctg gctggtctgt aagttttcat taaccaaaat ggtcttatcc
    58141 agagcacaag ccacttgtcc ttgcaaaagg tgtgtatttg gcctaaagtt aatggctaaa
    58201 atagccaaat caccttggaa ggtgtcccct tgctcggtat gagcgacaac ttttccctct
    58261 atctcatgaa tagccgtaac acgcttatta ttaataaagg tgacatggtg agtggacatt
    58321 tctgccatta caggggctat cagttctgcg tcagtctgat agaaatctgg acgttcggct
    58381 gcttcaatca gtttgacccg tttgccttgt aaggacaaac tgtaggcaag gtctaagcca
    58441 atcaagccgg caccaataac caagacctct tggctagcct caatcagttt taaactagct
    58501 tggctttctt cataatattt ggttaccaaa actttgttgg tctgtgacgt ctcaatataa
    58561 tgagactggg ggctagcacc catggcacaa acaagcgttt cataaccttc ttcaaaaact
    58621 cgtccttgac tgtctttgag aagcaaggtg tttgagggag cttcgatagc taacacttct
    58681 gcttgaataa accgatggtt agactctatt tgtgctgcta ggcaggctct tccccacata
    58741 gcatcagaca ggtcttgaat gtctcctctg aataattggt tgataccatt tggaatataa
    58801 ttgggacagc tttccttatc aatgagaatg atttgggaat ctggattgag gtccttatat
    58861 ttatcaacaa aggctagacc agcaaaggat gccccgataa catgtatggt ctttgtcgtt
    58921 aatgtcataa tagtattatt atagcagttg tttttaagat atgaaagcgt tttacctaat
    58981 cctataaaga aaatgcaaag gagctggcct atgatagcca acccctttag tgatggttag
    59041 gacatgactt ggaaaagcaa aactgctaaa gccgctccaa taattggtcc tacaacaggt
    59101 atccaagcat aagaccaatc agaatctccc ttgttgttga gtggtagaat agcatgaact
    59161 agacgaggtc ctaaatcacg cgctgggtta atggcgtaac ctgtcgttcc tcctaaggat
    59221 aacccaatcc caataaccaa ggtacctaca cagagggttc ctagtcctgc tggcatatca
    59281 tataagccaa atgccaaaat accaagcatc aagacaaagg tcccaaagat ttcactcaat
    59341 aggtttgagc tagtatctcg aatagcagga cctgtcgcaa atgtccctaa aatatcagcc
    59401 tgactctcag cagccagata atgtggcctg aactgaagga ataccagagt tgaaccaacc
    59461 atagctccca atagttgggc aaggctatag gcaatggctg ttgaccaggc aatggttcca
    59521 ctcatggcaa aagcaaagct aacagctgga ttgaggtggg caggggcaac tttgccactg
    59581 ataaagactg ccacagcaac tgcaattccc cagccagtcg caatcacgat ccagccagaa
    59641 gcatgggttt tcgttttggg caagacaacc cctgctacca caccatttcc tagtaaaacc
    59701 aataaggctg tacccaaaaa ttcaccaaag atatccatat taaccctcct gatggccttt
    59761 taaggcactc aaatcattgt ctgcaatcac gcgacgaaga tcgtcttctt gtgccactct
    59821 ttcctgatca gaccattcaa aatgtttagc catttcatta atcactgggt caatcaaagc
    59881 atctaggcta tctcgcataa ataagaggtg atttgttctt ctcaagaaat aatctgtcgg
    59941 tttaagagcc atttcataat ccatcgcata atgtaaggac aaggtttcag ctaaacttaa
    60001 cccttcagct gctgttaatt gacgagttaa ggcaaagact tttggcgcat tagaaccata
    60061 aaggtttgcc aaatacctag catcatccat cgaaagacca ctaagagttc ctaattgagc
    60121 ataggcttct atttccgaat ctacattggc tggattgatt tcacctcctg aaacaggata
    60181 ggtttttgaa ttgataagct tgaaggattt gccaaactct tctttgagga tttgaataat
    60241 ccctgtcaat gctccttcag ccattttgcg atagtcggta atcttaccac ctgccaaggt
    60301 aaagagtcca ttctcatcac gatcaaaact tgaacctcgt gacactgcag acggatccaa
    60361 ttctttttca gatgtgctgg tttcaacctg cttaatagct ttttcaacag cttctcggct
    60421 atcttcgtgg ttaatatagg ctttgacagt atcaaccaag tgatcaaaac tatcatcact
    60481 gactttaccg ctgttgccac cattgtagtc agaagcacta ttacctgata acaaggggcg
    60541 aagaccagcc caactgcttt caatatcatc aatggtcacg ttggcatttg gaaagcggtt
    60601 attgacaacg cctaacaaat aatccacatc ttcttgagta acttgtgggt gctccaagtc
    60661 tccagtgtag tccgtgtccg ttgttccaaa ataagttttt tcttcacgtg gcaagacaaa
    60721 gaccatacga ccatcattta accctgtgtc aacatagaca ggttgagaca ctggtaattt
    60781 ttgacggtcc actaccagat gcaccccttt tgtagggcgc atttgatgaa tcggttgtcc
    60841 cttatgagag aattgacgaa tctcatcact ccatggacct gtggtgttga tgactaattt
    60901 agccttgata atgatttctt gatctgacag cagatcacgc gccttcacac caataatctt
    60961 accattgtca tctagcaaga aatcttctgc tttcacatga ctagcaataa gagccccatc
    61021 atgattagct cgtttgatat tttcaataac aagccttgcg tcattattgc ggaaatcaag
    61081 gtaaacccca ccaccaagca agccttcttg ttttaagtct ggttctcgtt ttaagacttc
    61141 ttctttggtt aacaccttgt tggccgctgg cgtattggac acgcctgcta aaagatcata
    61201 caaatccata gcgaccttca aacggaacat gctaaaggtg ctgccaggtt cgtcataaac
    61261 aggtaataac atagggtctg gttttggaat gtggggtgca atttgttgca ccacagcccg
    61321 ctctgacacc gtatctgaaa ctacctccac atcaaattgt ttcaagtaac gaagcccccc
    61381 gtgaaccaat ttggttgaac ggctagaggt tccttgcgca aaatcttgca tctcaatcag
    61441 acccgtatct aggccactag ctgccgcctg aagtgccaca ccagcacccg taatacctcc
    61501 cccaataatc agtaggtcta aatctctttc ttgcattttt tggagagcta agcgtcttgt
    61561 ttctcttgaa aattccattc catcctcctc tagttatttt gcatcgtcat ctgcatcttc
    61621 ttcttgggtg aaaacttgag ttgctttaac agcgcgcttc caacccttgt ataatttttc
    61681 tttgcgcgat tcattcatgc tagccttaaa gagctggcct gtggcattta actttttcaa
    61741 agcatccata tcttcccaat accccacagc aagccctgct aagaaagctg ctcctagagc
    61801 tgttgtttct aaatttttag cacgggcaat atcaattcct aaaatatcag cctgaaattg
    61861 catgagcata ttattcatgg ctgcaccgcc atccacacgg agctgttgaa tgtcaatacc
    61921 tgaatccacc tgcatggtat caataacatc tcgcacttga taggcgatag attgtaaggt
    61981 tgctttgaca aagtcttctt tgctggtacc acgtgtcaag ccaaagacag atccacgcgc
    62041 attagaatcc cagtaaggag ctcctaaacc ggtaaaagca ggcacaacat aaacttcatc
    62101 gtcactagtt gatgctagag cgaactgttc agattctggt gaagtctcaa tcattttaag
    62161 accatctcgc aaccattgaa tggcagagcc tgcaataaaa atagagcctt ctaaagcata
    62221 gtgaaccttc ccattaatcc cgtaaccaat ggtggtcaaa agattattac tcgataactg
    62281 catctcatca ccagtattca tgataatgaa agaaccggtg ccataagtgt ttttcaccat
    62341 accaggctca aaagctagtt ggccaaacaa agctgcctgt tggtcacccg ccatacctga
    62401 aataggcact tcgcccccat aaaaatgaaa ggcagctgtt ttgccataaa tttcagaatt
    62461 ggatttaacc tctggaagca tatcttttgg aatatttaaa agctctaaaa tctcatcatc
    62521 ccatgttaag tctttaatat tatagagcat ggtacgagcc gcattggaat aatccgtcac
    62581 atgaacagca ccatctgtca atttccaaac cagccaagta tcaatggttc caaaaagtaa
    62641 ctcgcctttt tcagctcgtt cttgagcacc aggaacatgg tccaaaatcc aacggatctt
    62701 ggttgcagaa aagtaagcat caataacaag gcctgtcttt tcatggatca tttttgtatg
    62761 gccatcttgt ttgagttgct cagcaattgg tgccgtctgc cgtgattgcc acacaatagc
    62821 attataaata ggtacacccg tttttttgtc ccaaaccact gtggtctcac gttggttggt
    62881 aattccgatt gcttcaattt ggcttggttt gatgctggac tcaataaaag cacccgcaat
    62941 aacagactga accgaattcc aaatctgatt agcattgtgc tctacccaac cagcgtgtgg
    63001 gaaaatctga gggaattctt tttggctact gctaaccttt tccccttttt gattgaaaat
    63061 aatcgctcgt gaacttgttg ttccctgatc aatagccatg atatactttt cttgcgacat
    63121 tcattaccct cctttaagta agcgttttcc tatttgattc tattatagct aattttatca
    63181 gaaatatatt atcaagaatt tttaaagcta aaaaaaagct gataagatag gtagcttatc
    63241 ccactagatg atcttgaaaa atccactgat gacaaccacg tctcctcatt tctaacgagg
    63301 taatctttct tatcaaagaa aatcaaaaga cccaacaatc actctgctaa tccagagtca
    63361 tcattgggtc ataaagagaa ctaagcctca aaggcaacac ggtatcaaac agccgcgcct
    63421 aagaggcaaa gacaattgga cacaagagtt aaggctgtct tattcattac agttcttgat
    63481 tagtcattga ttggttcaga agatttttcc acaatatccc ctgagttggc gtcaatggta
    63541 tagctgtatt cttgatcttt gttttgaaac tcgatttcat acacggcttt gccatcttca
    63601 ttatcttgtg taactgatag catttgagca tcagcttccg taacagaagc atcttttaac
    63661 gcaattgatt tggctttgtc ttctgaaagt ttaactttct ggctagtttg acttgtcttt
    63721 ggttgattat ccatatgatc gtctttatca tccatatcac aggctgcaag actgagtaaa
    63781 gagaggctgg ctatggctag tagagagaat tttttaattg tcataagtac taccttcttt
    63841 ctttgatttc ttctattata actcaaacac atggtttttc ccaatatttt gactatacaa
    63901 tataaaaacg tgtggtcact ttgaagtatc ataccattta aaataaaagc taacagtcat
    63961 cacgataaac aaaaagcagt tcagagctgc tttttgtctt atgattttgg gtcatctaat
    64021 gaacggccgt gcaagccttt ttcacgttgc acctgtctta atttttcagg ggtcacgtcg
    64081 tttccttctt cgtccaccaa tttgatgcct tcgatatggt gtctgacaga gcgacgatag
    64141 ccttcaatgt attcttcacg gagttttgcc tgttccactt tttcaggtcc agtcaagcct
    64201 accgtttttt tctttttagc cagctcattg atacgagcaa tttttttagg atccatgtta
    64261 agccactaag agcctgggaa aaaagtataa ggcttaaaaa actgacttga ctctcactgt
    64321 gaaaagcaat gtttaaaggc cttgtttttt ccactcgggt actgaactca cttttctagc
    64381 taagtcccca acggctcttt cctttctatt tacttggtgt ttagttggtt aaaagcagca
    64441 atggtcttag ctttgcttac taaatctgat aaaatagcta aacggttgtt cttaagggct
    64501 tgatcttctg ccataaccat tgtgttatca aagaaatcat taatcactgg gctaaggaca
    64561 aagacctgtt ctaactgctg ggcagcactg cctgctagag tcaagccttg aatagctgca
    64621 aacaaagtgt tttcttgctc attctcaaag aggctagggt ccacctgaac agaagcgtcc
    64681 gctttttctg ccaaattaaa agcacgtgac aaagattcaa ctgctggttt gtaattttcc
    64741 gtatggctgg ctttgacaag tgcttcagct gcggccaaca tttctggaac cacaaaggtt
    64801 gaacttgcta gaatagcttc ccgaatgtct tttggtgcgg ctttgcccat catcttatcc
    64861 acacgagcac ggataaagtt catcacatcc gccttattgg cataggtcaa actatcaaag
    64921 gacaagtcat ataagctatc taccagctta tccattggga tgcgccatcc aaaatgatca
    64981 agaatacgga caatcccttg ggttgcacga cgtagagcat aaggatcatt agagccagat
    65041 ggaatcaagc caacagaaaa gaatgacaag agagtatcca atttatctgc caaggccagg
    65101 acagcgccaa ctttggtttc aggtagcgca cctcctgcag catcaggtaa gtagtgttca
    65161 cggattgctg ttgccacagc agcatcttca ccagctagaa gggcatattt ttcacccata
    65221 atcccttgca gctcatcaaa ttcacccacc atacctgtta acaggtcaaa tttgtaaatt
    65281 tgggcagcac ggtcaacagc tgtgacttcc tcagcagata ggttggcttc cttagcaagt
    65341 gatgcggcaa tgacacgcgt acgatccatg tgttcagcaa gagagccgat tttttcatgg
    65401 aaggtcacat tggtcaattt ggcaaccaaa tcagcaattt gcaatttctg atcctcacgc
    65461 cagaagaatt caccatcttc taagcgagct accaaaactt tttcgttccc tttaataaca
    65521 ttttcaatgg cttgatcatt cccattacga actgatacaa agtttggcat caagtgacca
    65581 gcctgatcac gtaccacaaa ataacgttgg tggtttttca ttgatgttac caatacttct
    65641 tctgggacat caaggtattt agcctcaaaa cttcccatga aagctgttgg aaactcgacc
    65701 aagttcaaaa cttcattaag caagtcttcg tcaatgtcaa cttgcacacc ctgctccact
    65761 tcaagcgtct tgatttgctc cacaatcatc tcttgacgct ctttagcatc agcgataaca
    65821 aactggctgc gcaaatcagc ctcataagaa tcagcacttg tgatagtggt ttcagtacct
    65881 aaaaaacggt gaccacggct gacgcgtcca gaatgaatat ccaagaagtc aagttccaag
    65941 gcctcatcat tcaacagaac tgttaaggtg tgaacaggac gaatgtattc aaaactattg
    66001 ttagcccagt gcatgctgat tgggaaggtc attgctgaca acacttcagt aacgcctaga
    66061 agcacttcct tagcaggttt tccagcttcg tgtttggtca cataaacgta ttcttctcct
    66121 ttgacttcgc ggaattcgat agcatctgtg gtcaagcctt tgccacgaac aaatccttga
    66181 gcagcttttg agaaattccc atcagcatca agggcaattt tcttagcagg ccctttaaag
    66241 tcctcagtca aatccgtttg ctgatcagct aacccagaca cacgcactgc caaacggcgt
    66301 ggagttgaaa aggtttgtat atcttcaaaa gagagacgat tttctgttaa gaaagtcgcc
    66361 aagcgctctc ccagttgttt ttcacttggt gtgaccacgt aggctggaag ttcttccaga
    66421 ccaagttcga ttagtagatt tttactcata attaagatac caagggcgtt aagcggacac
    66481 catcaaaata gcaaatcgac gcaggtgctt gcacctagga agtctttgtc tttttgacat
    66541 agtccgtagc ccgtgttcag ttcctttctc taaaaagtat ctttttgatt tttcccttag
    66601 gtagggggac gcaaggtgaa attatccagt ggataatttc agaaaacaaa agtgttccat
    66661 tcctagttag ccagcctaaa gtctcgccaa ctccctcgtt cgataagtaa ccttaccgaa
    66721 ttgtcactac agcgggagta accttgactc ggcgaccttc ggtcgcccac ttcttgctcg
    66781 ctcttaagat tacaaagctc gcaactagat catctttaaa tagacttatt cgccatcttc
    66841 agctagcaag attgcgcgtg ttgcttcatc caacagtgga aatccaagct tcttgcgttc
    66901 tgcaacaaag gtcttagcaa cgacacgtgc caaattacgg atacgagcaa tgtagcctgc
    66961 gcgttctgtg acggaaacag cgccacgggc atccagcagg ttaaacgtat gagaacattt
    67021 gagcacgtaa tcataagctg ggtgaaccaa accttcttct agggcacgcg aggcttcttt
    67081 ttcaaacttt tcaaagtttt caagcagcat gtcttggtct gatatttcga aggaatattt
    67141 tgaatgctca tactcaggtt gcaagaagat ttcaccatat ttaacacctg gtgcccactc
    67201 aatatcatag accgaatcca cttcttgaat ataggaagct aagcgctcaa gaccataagt
    67261 tacttctgct gtcactggag atgtcgcaag gccaccaact tgttggaaat acgtaaattg
    67321 tgtgatttcc attccatcaa gccaaacttc ccaaccaagc cctgctgatc ctgttgaggg
    67381 gttttcccag ttatcttcaa caaaacgaat atcatgttct aaaggattga tgcccaattt
    67441 ttccaaagaa gcaaggtaaa gttcttgaat atttgatggt gatggtttca tgaccacttg
    67501 aaattggtgg tgttggtaaa gacgatttgg gttttctccg taacggccat ctgcaggacg
    67561 acgtgatggc tctacataag ccgcattcca tggctcagga cctatagcac gtaagaacgt
    67621 gtaaggactc atggtcccag ctcctttttc attgtcatag gcttgcatga gcatacaacc
    67681 ctgatcattc caatattgtt gtaaggtcaa gatgatttct tgaaaggtaa gttttttaga
    67741 catttcgtac tcctttgata gtagtaaaat ggtatatcat tgacaatcgt ttttttgtca
    67801 tcagtacaat acctgacgat gttactagca tgtattacag gtctaggcac caaaaaaccg
    67861 cattttgatg ctcctaaatc ataagaccta ggggcgtcaa aacgcggttc caccctaatt
    67921 tattacttca tttatatagt atctttttgg gcaatattga caaatatact taatcacact
    67981 gcccaaacgg aagcgccaat ctgcagtcct accattcggc tctaactacc ccgaactcgc
    68041 tttagataag atacttgcat cctttttcct agagtctagt ttagcataaa gccattagtt
    68101 tgtccatcat gagcttaagg ttttgttcga gtaccgtttg gaataatcac ttccgctaat
    68161 agcttgtttt cttctcgaat acgtaaatat attactacaa tgtagcatgg gaaaagaagc
    68221 atagccgtaa ttttagcatg gcaaagtaag gctatgccca ccagctcagg ggcgatattt
    68281 aaaaagtagt taggatgttt aatcgttttg aacaaccagt gatccacata tttgtggtct
    68341 tttgctaaca tcaattttac agtccaaatg tcacctaaga tacgtgtcac ttcatataaa
    68401 acagctactg ataataacat caacaaaaga cctaaaaaac tgatgccatc aaacttaatt
    68461 tgtttaagca gcgcttcaat caccgcaaac acataaatca taatgtgaag taacgtcaaa
    68521 aatttcgtgt tctgagcacc aaattcctgt cctccttggg ctaatatggc tttttcattt
    68581 gttatcgatt tcttcaaaaa tactaaacga atagtaaaca tagctaacat cactaaaaag
    68641 atggtcacaa tacggctcct tattttcaat aatagtttct ttcacaaaac actaataaag
    68701 attatagcta aatgataaac ctttgtcaaa ccgttttcaa aaaagattta gcgaattatg
    68761 gctaaatctt tgtagttcct taaaaacttg tattatcagg gttaggaatc gctgacattc
    68821 ctgagagata gcgaattgtt tttttatctt cttgtgtcaa gctcacatca aaaatagcca
    68881 tattttcctt gatgcgctca tcatgcaccg attttggcaa gggaataaaa ccttctgcca
    68941 gcgaccaagc taaggcaact tgtgccactg ttttgtcata tttattagct aactgctgca
    69001 tagtctcatt atcaaaaatc tccccttgtc ctagaggact ccaagcttcc aataaaatct
    69061 catttgcctt acaataatca accacttcct tttgatagca acctggggct aatcgaatct
    69121 gattaattgc tggagttatt ttagctgtct cttgaagagc ttctagatga tgcaccataa
    69181 aattgctgac gccaatgctt ttaataagcc ctgcttcaac cgcctcttcc atatattgcc
    69241 atgcttgggc atttgcctct ttccaagtgt tacgcagagc ttttgggttt ggccaatgga
    69301 taagatagag atccacataa tccagaccaa gacggtcaag agaagcagct aaagcgtctt
    69361 ttgccccttc ataactatgg gcgtcattcc agagtttagt tgtaataaat aagtcttctc
    69421 gtagaacccc agaatccttg atggcacgac ccacactttc ttcattttta taaatagctg
    69481 cagtatcaat atgacgatag ccagccttga tggctgctaa ggtagattgg taagcttcct
    69541 caccatcggc tgcttggtaa gttccaaatc ctaaaacggg aatctcataa ccacttgtca
    69601 tttttactgt tgttaccatc acaaaaacct ccttttatca atctctgtaa gcgattactg
    69661 taatctattc tatcataaag aaagaaaata caaaaagaat tggcctgcca gacatagcta
    69721 ccccaatcct tttgtatctc ttaggcatca aaagcttttt gcccatttaa ataggttgca
    69781 acaagtgtta aatccttatc aagaacaata aagtcagccg catgcccagc tttgatttga
    69841 ccacatacgt cgtcaatacc gacagaaaca gctggcacat aagttgccat atgaatggct
    69901 tctgccggag ttgcgattcc ccaggtcact acatttctaa ggccgtcttt taatttcaaa
    69961 atagatcctg ccaagtttcc actctcttta agacgagcag tgccatttgc cacaaccaca
    70021 gagaattccc ccaagaggta atcaccatct ggtgaaccac ctgctcgcat acagtccgta
    70081 atcatggcta catgatcatg ccctttttgc tgcatcaaaa tatcacaagc aactggtgac
    70141 acatggtggc catcacaaat caactctgcg taagtatttg gaagattata aaccgctccc
    70201 accattcctg gttcacggtg ggtcaatcct cgcatgccat tataagcatg aacccaaaca
    70261 ctagcaccag cttgaacagc ttctttagcc tcttgataag taccgtttga atgccctaag
    70321 gccactgtta cgccttgttt tgtcactgca gacacaaatt ctttgacacc atcacgctca
    70381 ggagcaaggg caattttttt gatgagccct ttagcggctt tttgccaagc atcaaattcc
    70441 tccaagcgtg gggttttcat ataacttggg ttttgagcac ccttatattc ttcggtaaaa
    70501 taaggacctt caaagtaaat accttgtatt ttagcacctt ttacctgatc agcaactgaa
    70561 gcaatagtcc ctgatacttt ttctaactgc tcaaaggtag aagttaaggt cgtcggtaaa
    70621 aaagacgtta ctcctgttgc taatagtcct tcactcattt gatgaatccc ttgggcagaa
    70681 ttatccatga catcagctcc cgcatagcca tggatatgcg tatccacaag acctggtgca
    70741 atttgataac cggtgtagtc aatgatttgc gcatctgccg gaacaatttc tgtccactcc
    70801 ccaaaaacac catcatgaag acctaggtag ccagccggtt tcacctctgt tgggtaataa
    70861 aaacaatctg ctttaagata gcatgtcatc ttttttcctc ccttttttcc ttattatacg
    70921 ccttattctt tactttgtaa atggtatata ccactttttg gattcaaaaa agaaaacgtg
    70981 gatgatcatt cacgttttct ctttttttaa agctggtgtg aaagtacttt ctctgctaaa
    71041 ttcaaggcat gatctgtgat gcgggtatag tgggaaataa tatcaataaa attaatacct
    71101 gcttgtgccg tacattctcc acaattcaag cgcttaatgt gggttttacg taatcgtcgc
    71161 tctttttctt caatttcttt atggcgagtc acaatagttt gcgccaagtc tgtatcacta
    71221 tcaacgatag ctctaatggc atctagtgtt aaacaatgcg tcaattgata catctctgtc
    71281 aattcttgac gagcagatat tgaaaaacca atttgtttag atatgatgcc ttcaattaga
    71341 atacctaaag actcagaatg atctccaatt ctttccaaat cacgtgaaga gtcaagaata
    71401 ccagccaaga cttcattttc acttgggctg agggcttcgt tagaaatatc aaccaaataa
    71461 gtggttaact cctcatcgat ggtatcaact gctctttcat aacgcttgac cttttccccc
    71521 aatttatcgt cagctgtcat aatataactg taagaagctt caaaagcttg aatcgcataa
    71581 gaggctaaat gaaccaattc cttgtgggca tttcctagtg cgatagaagg ggcttgggta
    71641 ataagtaagc gatctaaata aagggcttcg tatttgacca cttcatcttc tcctggaatg
    71701 agtctagtca caatcatagc tagtagacta atgaaaggaa ttaataagat ggtattagtg
    71761 atattaaaag aaccgtgaga aaaagcgata gtcatctcag gcgttaaact caactttgat
    71821 tgtagccata acatcaatga tgtgaatggg actaggataa tcataaaaat aattgtaccg
    71881 atcaaattaa ataacacatg agctgctgcc acacgtttag cagcaatatt tgaacctata
    71941 gctgctaaga cagctgtaat gcaggttcct atatttgagc ctaacaaaat aggaatagcc
    72001 ccctgtaaag tcaaaagacc acctgaaaac agaccctgta aaatcccgat aatggctgcc
    72061 gatgactgaa tcaacatggt caaagccgtt ccgataaaga caccttggaa gggtttatca
    72121 cctaatgtcg ctaaataatt ttgaaaggct gacacagatt tcaaaggatc catggcatct
    72181 cccattaggt tcagcgagaa gaaaattcct ccgacaccaa aaatgatacg cccaaaattg
    72241 ttgagctttt tattagaggt aaagaaaaga caggctgcac caataaaaat catgggcaag
    72301 gcgtaatctc ctagtttaaa accaattaaa aacgaagtga tagtcgttcc aatattagcc
    72361 cccataacaa ttccaatggc ttgtcgcaaa tttagcaaac ccgcagaaac caaaccaacc
    72421 gtaatcacag ttacgcctga actggactga attaaggcag acatggcaat tccgactaag
    72481 ataccaaaaa agggattact ggtgtattta tcaatgtaat accttagttt atctcctgct
    72541 gcttgttgca gaccatctcc catatacttg atactgaaaa gaaagagacc taagcctcca
    72601 aagaaatgaa atgcaatgtc ttgccaattt actgacacaa tattgtcctc gctcaatttt
    72661 atagtctatt ctattttaat gtattacggt ctttatcaca aggttttttt aagcgtttct
    72721 gtgtataccg atgtcaacat ttgcatatta ttggtttgat aaggtgttag gcttttccga
    72781 tattttacat catttgtttt tgcacaaatc ttttcatttc gtttaattag aggtataata
    72841 tggctacgat gaaacaatat cataaaggag attccatgac taaatcacaa aaagaggcgc
    72901 tttattggat gttgagtgtt ctaactatca ctctaatagg tggctcctgc cttatttttg
    72961 gatcccaccc tcaaacgcaa gataaggtag ctaaacattc taaaagtgct gctagtttac
    73021 taaaaaaagc agttaaagca gttaatgacg ctgatcgttt agccactgca gctgctatcc
    73081 aagaagccca gaaagctgtt gataaattag cagaatcttc taagaaaaaa acgctacaag
    73141 aacagctaaa cgttgccaaa gcaaagcaag agcaagaaga tgcagctact caagcagtta
    73201 aagctgctga ggagactctc aatcaaaatc ttaaagatat cgcccaaaaa gcagttaacg
    73261 acttaagtaa caaaggtaaa aaagccgctt tacaatctcg gttagacgct attttaccag
    73321 caaaacccat tattgatgaa tttccaagac aaagtggaga aataacagat aactcttact
    73381 ggacaccttt cccaggagac gtctcagata cttatgataa ttcccagtca cctactttag
    73441 acccaagctc agaatcttca gcttcagatg ttacgccaca acctagtcat cctgatccaa
    73501 ttccacctca gacctcttca gaaccttctg actcaggaga caagcaatca tcaaaagagt
    73561 aatacaaaaa tttttcgtaa aatcaatcaa taaacgtttt agacggctat cttagtgatt
    73621 agtcttcctg atatcttaaa aaagctagct caaatcaaaa gagtctagct ttttgttttg
    73681 ttagatagca ttaaatttcg tagcccatta aaagtcctcc gtcttcagca taaaagctac
    73741 acaaacctga ggtccttcca gtttgaatca cagcatcagg atataaagat ttgatttttt
    73801 cactgatctg ctcacaaatt tttggatttt gagcatgagc aatgtaaact tttccgccta
    73861 cataaccctc tttttgaatt tcttctatca aagcagaaac tgcttttttt tgaccacgcg
    73921 ctttttgaag aagttcaagc gttcctttat tgctagcttt cccaaccatt ctaatattga
    73981 gtaagccaat tactttacct actaatttac tcagtcgacc atttttaacc aaattatcaa
    74041 ccttggcaag cacaaaaatc aaacgtgttt tttgctgata agctgtgatc tgtttgacaa
    74101 cttcttcaaa ggataatcca agattgatca accgctcaag ctccagtacg agcaaatcca
    74161 tctcgccacc tgctgataaa gaatcgatta ggtgaatatt gacattagga ttttcttcaa
    74221 gaagttcatt tttagccagt cgtgcactat tatgactgcc agataaggtc cctgtaattg
    74281 tcatcacgat aacattatct gcacctctat aggcctgcaa aaaggcttct gggcttggac
    74341 agctagatgt cgttgcttta gacgactggt acatagttgt catcatatta tcgatatcta
    74401 atccatcatc atctctaaaa atttctgtgc caatctgtag ggtcaaaggc acacgttcaa
    74461 agcgcaactc tttggattgt ctagtcaaac ttctaagatc acatcctgaa tctgttacaa
    74521 ttttccaagt cattttttat ccttcttttt ctctaatttg tgttcggtaa caaagaccag
    74581 attattaagc cttcgctaag atgtctaggc taatggtaat aactaatcat taaatcctat
    74641 gttttattac tagccttttc aatagttagt aaagtcatcc aatagagcta tacaaggagg
    74701 taatgaggct cctgataact aactttagtt gacaaactaa ggcttttccc ataaaattat
    74761 atcattatta agtcggtttt tgctactgat aactcatcag atgtaacact tgaaaggtat
    74821 ttgtgatgac tgataaagca ctctcaaaaa gatcacttca aaacttaaca caatttaata
    74881 aagaaacacg acgcatagca cgtgaatcta tggaaatcgc cttactgaat cttctagaaa
    74941 caaaaccttt aggtgatatt acgatttcag aattggtgac gaaagcagga gtatctcgta
    75001 acgcttttta tcgtaattat acctctaaag aagccattat agaacaactg ttagtagggg
    75061 ttatccgtcg tatttttcgt ggactaaaac aatttgatat taaaactcag gcttatcaag
    75121 cctggctcta tctttttact gaagctaaaa aagaagctca gcttcttaaa atgattttca
    75181 aacatcacct gcaccatctt ctaacacgat tagtcactaa acgtctgaaa gcttatcaaa
    75241 aattaaaaga caaaaaacaa tcgcactata agcgcctttt ttggagcaat gctattgttt
    75301 ctgtcttgac aaactggatt tcagatgaca tgatcgttcc tgccgaagaa atggctgcta
    75361 tgggcttgcc tctattaacg taaaaaggtt ccttttggga acctttttta tataatagtt
    75421 agtctttttg agctgcaagt gcaaactgac ggatagcctg ggccacaccc gccatatcat
    75481 tagtcaaagt gactttgtca gctaatggct tgatagctgc tgaagcattt tccatagcaa
    75541 ctcctaaacc agcataagtt aacatctcaa tgtcattggg agcatcccca atagccatca
    75601 cttggtcagc agttaaaccc aaatcttcta ctaattcttt gagagccgat gccttgctga
    75661 ctccctgagg gagaatttct aaaatattat cttggctacg aacaacatga aaactctgac
    75721 taagctgatt tctcaccgca cgttcaaagg catctagcgc agctttttct cctaagtaca
    75781 tggcttgaaa aatcaggcga ggagtgtccg acagctctgc taaggagaca ggcttgacaa
    75841 tggtaaatac caaatctcca tcttcctgca caaggtctgg cacttcttct tcaagcacca
    75901 aataatcgtt ttcctcagtt aaagtcaggt aaatatctgg aaaactttgg cttagctctt
    75961 ccagcaattc aatatctgaa accttcaaca tttttgaatg gcgtaattgc cagtcaggac
    76021 tactataagt actacagcca ttattgataa tgaggaattc ctcttgtgtc aaacctaatt
    76081 ggtcaaaata gggtcttgtc cctgactgag gccggcctgt gcataagaca atttttaagc
    76141 ctgactgagc tgcttcttgg atggctgtga tattctcttt tggaatctgt ttgtcctggt
    76201 ttaataaggt gccgtccaaa tcaattgcaa ttagttgaat catcctatct ttcctctttc
    76261 catttgattt tagggaggtt ccatttttta cggttgccaa tcatgcgtaa agtcgtgagt
    76321 aaaacaacca aggcataaca ttcaatcgtt gaatctgcta gtttaaaatg caaaacaata
    76381 gctgcaagaa tagaccaccc agcatagatt tcactacgca aaacactagg ttttcgccct
    76441 gccagaatat ctctgacaac accaccgcct gcaccagtca acacagctgc tacaatgaca
    76501 gcacttaaag gctggttaag acggacagca tgcaaggctc cttggacact aaaagctgcc
    76561 agaccaatgg catcagtcaa aacagctgcc cgtacccaac ctctagctat tagcttagga
    76621 aaaagcataa tcaaaaccat agcaaagaaa gcgcaagtga attctggctt ttgcccccat
    76681 aaggcctcta taggtaaacc aattagggtg tttcgaatgg ctccgcctcc aaaggctgtc
    76741 acgaaaccta aaataaaaat ccctaaaata tcaaattctt cttccatggc aacaatagca
    76801 ccagaaagag caaaggcaat ggtcccgatg atatttaaaa tttcccacat atcaattgtc
    76861 ataagctacc ctattgtctt ttagtcttct tttagtttac cacgttttcc tttaaaaaat
    76921 aagtagaaaa agataaaatg taaggataaa aaagcaagga taaaacccat tttcatcctt
    76981 gctacaaaag attcaaacaa ttatccccat acttatctta tcacatcaat gagagctgct
    77041 tgataggata aggttgtttt agattttttc cgtccaaggg ctagctgtct cttcgagtac
    77101 cctgtttaac tcgtcaatat tttggaagcc ttcagtgcat agccactttc ttgcttcgtc
    77161 ctctccttta gtaatataaa ctggaacgga tcctgcccac gtggcacgcc cacacaaaac
    77221 accgctaaat tgagcacctg ctgctgctgc aaagtataat gtctcttgaa aaagtttggc
    77281 agatacgcct gcactcaaat agatataagg gaggtggctg gcagcttctt ggtcttgaaa
    77341 agctttaata gcctcagctt gactgtaatg gacttcccct tcagtaaaac cttctacata
    77401 agccatatta acaggaacct ctacttttag cacatcaacg ccaaaacgct tatccgaaaa
    77461 tactgacata gcaccgttaa ccttatgtgg cttaagcttt gcgtatgccg cactgttgtt
    77521 atctgatatt ctctcatcat aactcaaaag ttcaagaaaa aaagggatgt cttcagctgt
    77581 acattctgaa ccaatgcgtt caatataagc ttgtttttgt aaattgattt gttcatctcc
    77641 atcaacatca taatagagca aaaatttaat agcatctgca cctgctgctt tcaaccgttt
    77701 gaccgaccat tccactaagc aatcgggtaa acggctagtg gttgtagcat cataacctgt
    77761 tttttcgtaa gctaacagta agcctgtctg attagctctt accttagtag ccagcaaccc
    77821 atattctgga tctaataaaa tagatgaagc ataaggcgtc aattcctcag aaacgagaac
    77881 tttcaatgtt tctatctgtg taactgtcgc ttctccttct tgatgtgctg ccatcatttg
    77941 cttcagtgca cctcgttgat caaaagctaa agctgatatg attccttgat ggctcacttt
    78001 ttctaagtaa tgtcttttat ttgctgtgat tgtcatgtga tacctctctt acttgaagtt
    78061 gctgatataa ttgtttaaaa gttgccatag tcatcaaatc ttgataatag tgagtagcta
    78121 gtctcctagg cagactgcct gagaagttaa gacatcaaac ggcttagcaa tagtactcat
    78181 gtggctcaaa gagacttcgg cttcgtccac atcactgtag ggaccagctt ccaaaatttt
    78241 tgtctgcatg ccttcatgta aaacagcaat acaatttctc gtttcccctt tgattttgaa
    78301 aaattggtta gaaatgccct gttcttgtaa ctgatgaatg ataaagtcac ccagtttacc
    78361 accactaaat cctgttgcca taactgacca gcttttgcta acattctggt cacatttagc
    78421 tccttatcac cagctgtttt tgccgttctg tcaacacgat taaccgtgtc catagccaga
    78481 caatctaaag gataggaaat agcgacagaa ggatttaaga taactgttaa actcatctct
    78541 tcttcctaat cgtgatactc accacgatcc catttttcca aaaattctgt aaaaaaatca
    78601 ggatcttctt ggttggcatg atgactttcc aagtgggcta ttttagcaat tagcttctta
    78661 ttctcttcag tttctttgta ttctgccttg ataaaagcat ctataatatc acacataaga
    78721 agttcaccag tgattttacc accaaagcca atcacattgg cattcaattc ttccttggca
    78781 taaagcgctg ttgtcatatc tcgaacaagg gctgaacgaa tacctggtac cttgttcacg
    78841 gcattattaa tgccaactcc agttccacaa atacaaacac ccaagtctgc ttgaccatta
    78901 accacagctt cgccgacttt ttttccaaaa atagggtaat gggttcttgt atggtcataa
    78961 gtgccacagt caataacgtc atagccttta gatttcaaaa aatcagaaac agccattttt
    79021 tcgttggtga caatatggtc acaaccaatc gcaattttca tcactttatc ctcctttagg
    79081 ccattttatt gagcatgtca acacgaattt gatgacgacc accatcgtag ggaccagtca
    79141 caaaaccttt gacgatattc ttcgctaatt ctggacctac aatctctgcc cctattgtga
    79201 tcatgcgggc attgttgtga ccgcgcgtca tgtaagcaga gcgttcatct gacacttcag
    79261 cagcaaccat tccttttaat tttgtggcta ccataaaggg acctgctccg taagcatcca
    79321 ccataatgcc taaacgacct tctgcttcat taacggcttt cgccaccgct aatgtgttat
    79381 caataaaatc actgttaata tcagtcacgt caataatatc atagccttct tcttgaagaa
    79441 aacttttgat caattctttt aatgcatttc cgtgtgcatc tgcacctaaa ataatagcca
    79501 tagcttttcc ttttctaacc caaaacgctt gccaatctag agaaggggga catgattacc
    79561 tgtccttaga tcaagatgat tgccagtagt cttagtgtct tccattattt ctttcaagac
    79621 aaagcacttg tgagttccca cagagcgcct tgccttacat gagaaatact cttttcacgt
    79681 tagggggtaa ggcagaaata ccttacgcag ttatctgcta ttctccctaa ttttttagtc
    79741 agtcacctga cctgatttta tttcattgtt ttcgcatact cagcgttacg tgccttcatt
    79801 tggttagcat accaagcaaa gagacctagg taaatggcca caaagatgat tagcgtgatg
    79861 attgaggcaa tctgacctgt tgtcgcttga ccaatcacat aaccaaaaat tttttccatt
    79921 ggtccttcaa gtgttgaatg cgtaatcaag gaaccagcgc ttgtacctgc tggaaaagcc
    79981 cctacttttt tagccaactc tgtcgcaaat ggagcaatca tagttcctga caagaggaat
    80041 aatggcaata agagggaacc aaaaataatc atgcgaatca aacgaccacg tgtgaccaca
    80101 agaagagctg gtgtcatccc catagcaata atccccgcca atggtaaaat cccattgcca
    80161 acttttgata ggagaacggc ttcaatcaac atgattgggg caagaatatt ggcacaggcc
    80221 cagatttcag cgcgaccagc aatgaaaggc cagtccaaac cgatattgaa acgacgccca
    80281 tgcattctag cattggcaaa attggtaatc ccttgtgaca aaggctcaac agctgcgata
    80341 aaccaagagc caatcaaaga gaaaagttcc aagcaggcac cagctgtaaa tcctagacca
    80401 aaccaatttt tgatagattc aacagtgaaa tgaggatctc ccataatccc aatcacaaaa
    80461 cctagagcca ttccgataaa gaacttagag ccccagaagc caattttttt gttcaattta
    80521 gcagcatcaa agtcatattt atctagcccc ggaaagacct tgtcaaaaat cttatctaag
    80581 accataatga ttggattcat catgtagttc atgtgagttg aagtcattgg tgattgagac
    80641 cctgtcccaa gaaggtcatc aaaggtcggt ttcatcaaat cagagttaat gattttcaat
    80701 accccaacaa gaataactgc cacagtagca atcaaaagag acacaaggac tggcaaatgg
    80761 ttgtgatcag cataccacat aatcaataga cctgtgatag acaaatgcca aatatcaaaa
    80821 atatcgacgt caagggtgtc cgtttttttc atgacaatca tgacaatatt aaccaccagc
    80881 atcaccagca agaaataaag ggtataaggg gaaccccagg taattgttgc aagcggtgcc
    80941 caaccgacat caataatgtt taaactgatc cctgtatttt taacaaaggc ctgcaaagac
    81001 tctgaaaaag cccccgtcaa aatcccaata atggctccaa tacctgtaag agcgatagct
    81061 aacttaatcc cgccttccag tgcctttgtg aatttaaccc cgaaaatcat ggctaaacct
    81121 gtcatgacaa tcagcatgac cacacctgat cccaactgaa taggaaatcc cagaatcttg
    81181 ttaataatgt ctaaaaaagg ttgcatcatc ttgtctcctt atgtttttat taactcacta
    81241 caaatggttt tctttaatca cgcgctctaa ttcagcaaaa acaggctcac tcatgattgg
    81301 gatacgatag agaatcggtc ctgcttctac tgtgggaatt ggcatctcaa atcccaagtc
    81361 agtttttgca atcggcgtaa aaatatcata acgagacacc aattcttctg tgatgtcttt
    81421 gaccatcacc gcatcacaat gcacatcata gccacgatca ctcatctgag tttcaatcgc
    81481 atctttaatt tgatggcttg agttaacccc tgcaccgcag gctgctagaa ttttaatcat
    81541 gctgaaacac tcctttttct attaaatagt ttgaaatagc ttgtttatca tcttttagac
    81601 tggctagata gctaagattg cctttcgtaa taaagaaggt aatgagattg gatagaatcg
    81661 tcgtttgacc ctcgttttga ctattgataa taaagaagaa atccgttacc aaacagtctt
    81721 cctctggatt aatcatgtgc ttaaaggtaa gggcttgact atttctaaca tagaccactt
    81781 gatcaaccaa gcaatacttg gtttctgtat gcggaatagc cgcatacaaa atatctgacc
    81841 catctttgag gtccactttg agtcctgtcg gaaataccgc ctcacgctcc actaaagcct
    81901 gatgatactc ttgcgtcaca tacccaacct tttccaagta gctagcaaca agatcaaaaa
    81961 gctctggctg cgtccttgct tcagtaaata gaatattagg aaacactccc taccgccttt
    82021 ctataagtat caatttttaa caactgtcat ctcatcatca acaaattggt aaccgtttac
    82081 aaaatcatta tagtataacc ttcaacataa ttcaacattt ttacgcaata ttttttgttc
    82141 tatatgtttg tttttgtttt atttattttg ttttattgaa atatgaaggt ctatatgcta
    82201 tgataaacat aagtaaataa actatagaaa ggagcccctt agatgttaaa aagagaaaga
    82261 cttctaaaaa ttaccgaaat agtcaatgag caaggtattg ttactgtgaa tgacattatt
    82321 cagactttaa acgtttctga tatgacagtt cgtagagact tagatgaact ggaaaaagcc
    82381 ggcaaattga tccgcatcca tggaggtgca caaagtatta ccatgcctaa taaaaaagag
    82441 cggtcaaata ttgaaaaaca aaccgttcaa acaaaggaaa aatgggaact agcttcatat
    82501 gcgacacaac tagtcaatga tggtgaaaca atctttattg gtccaggaac aactttagaa
    82561 tgtttcgctg agcaattaaa aaatcgtcag attcgcattg tgaccaatag cctccctgtc
    82621 tttaacatcc ttcaggacag cgaaaccatt gacctgattc ttatcggtgg tgaataccga
    82681 tctattacag gagcttttgt agggtccctt gccagtcaaa atatctcatc cttaaaattt
    82741 gccaaggctt ttattagctg taatggtatt tataaaaacg atattgcaac ttatagcgaa
    82801 actgaaggag agattcaaaa gctagctttt aataattcta ttgaaaaata cctcttggta
    82861 gataaccaaa aattcaatgc ctacgacttc ttcatttttt accatttaaa caacattgat
    82921 gctgttgtta cagattcgca aataactgag gacgttatcg aacgttatag tcagttcacg
    82981 caattattag tagcccacga aaacaagaag taaccgtttc atcaagaatg gacagcctgt
    83041 cagcgcatca tccttaaaca ccttctggca aaagtgattt gcccccagag aggtgttttt
    83101 gttttgctcg gaacacacct gctatcgtca gagtctttat gagtgaccac aaaaaaagaa
    83161 gcccagatta aaaaactgga acctcttttg agatgaagta aggctaccaa aataacctaa
    83221 gaccatttat gtaattcaaa tttggtatcc ttcaaagcac gcttgagtag gaacgttaaa
    83281 ggacgtcctg tcaccttagc ctctcctttt tccaaattta cctggaccga ttgcacaccg
    83341 gggacagctg ataatttttc agtaaccgtt cttgcacaac cgtcacacgt cattcctgta
    83401 acctgataat gtttttccat ttcgttttct ccttcaaatg gtttttcctt ttaatcgcag
    83461 ggcattcaaa acaactgata ctgaactaaa actcatggca aaacctgcta acatcgggtt
    83521 caatagtgga cctccaaaaa gatgaagtaa gcccatggcc actggaatca tgaggacatt
    83581 gtaaatgaat gcccaaaata aattttcctt gacaattctc atagtcgctc gactcaatga
    83641 catagctttc accaaatcca gcatatcagg tttcatcaga atcacatccg ccgattcaat
    83701 ggcaatatct gtccctgacc ccatagctat cccaatgtct gctacagcca atgccggagc
    83761 atcattaata ccatcaccta ccattgcaac ttttctccct tgagagcgga ggtctgctat
    83821 cacgcctgct ttttgatcag gtaagacttg actgatcaca tctgtaatcc ccacttgaga
    83881 ggcaatagcc ttagcggtag catcgtggtc acctgttagc atgatggtgt gaattcccag
    83941 ttgatgcaaa gcttcgacgg tagcttgact atcttctttg acagcgtcag caatactgaa
    84001 aagagctctt agctgcccct ctttagcata atatacaagg gtttgacctt ttcctgaagc
    84061 cttagcacaa actgactgaa cacaagataa atcgatacca agagttgcca ttaaagtagc
    84121 atttccaatc gccaaacgac gcccttcaag ctgaccagtg actcctaggc cggttaaaga
    84181 ctcaaactct tccactggta gactatcgta accagcttcc tgagcagcac gaacaatagc
    84241 ctcccctaag gggtgttgag aataggcctc caaggaagca gcttcttgca agataaggtg
    84301 atcatctccc gaaaaaatta ggagcttttg aagacttggt ttcccctccg taatcgtccc
    84361 cgttttatca aaaacaaccg tatctacctg atgagcttgt tctaagatgt caccaccttt
    84421 aaaaagaata ccattttcag ctgcacgccc tgttccaacc ataatcgctg tcggggttgc
    84481 taaaccaagc gcacaagggc aagcaatgac tagaacagcg atggctgttg tcaaactaaa
    84541 acgaagactt tcctgcatga ataccaacca aaacacccct gttaacagag ctaataccaa
    84601 aaccaccgga acaaagacac ctgagactct atcagcaata gttgcaatag gtgctttatt
    84661 ttcttgagca ttctcaacta gttggataat ttgtgctaac aaggtatcat tcccaagctt
    84721 atctggctta atcgtgaggg cgccttgccc attcaagctg cccgcaaaga cattatcttt
    84781 ttctcccttt tcaacaggca aactttcccc tgttaaaaag gattcatcca aactgctatg
    84841 tccttccacg ataatgccgt caatagaaac tttttcacct ggttgaacca ggacaaggtc
    84901 atcatagcta acttcttcta atggtaacaa ttgccattgg ctgtttctcc ataccctcac
    84961 atcagtagcc ttcaaggata ggagcttttg aatagcttga gaagtacggc ccttagaacg
    85021 actttcaaaa tactttccta gaccgatgag tgtcaaaatc actaccaccg attcaaaata
    85081 aagggagtgc acaaagtgcg cccggcccag actgatttca accactccat aaagactata
    85141 agcaaaagca aagctggttg ctaaagctac caaggagtcc atattaggat gtcccttaaa
    85201 caaagcttta aacccattat ggtaataatg acgatttaat actaagactg gaatcgtcaa
    85261 gagtagctga ctaaagctgt aaacgaaagg atagcgatct ggttgcagaa atggaggaag
    85321 ccataagccc accatgtgac ccatagctag gtataatata ggaatggtga atagggcaga
    85381 ccacaagacc tgagaccaaa taacctttag gtcttcgtca cgacgacctg tttgcatgtg
    85441 ttttgcatgt tcatcaaaga cttgtgcacc ataaccagca gctttcaccg cttgaataac
    85501 tttggccgtt tctaaatcgt catcttgata agtaaccgtg agcttctcag tcgctaaatt
    85561 cacaacagcc tgttctactt caggcaattg attgaccgtt ttttcaattg ttagagcaca
    85621 agaggcacaa ctcattccct ccactaaaaa tatctcttta gccattaata cgtctccttt
    85681 ctctgacagt ggcactgtcc aggcagacaa ttacacggca cctcaagaac tgcattttct
    85741 tttttgactt ctagtagctc ttggaatgcc ccgatttcct ctaaggtcat cggtaagtga
    85801 taaagccgtt caagaagtag acgcgtgtgt tgccgctgac aaataccgtc taaaacagtc
    85861 gctagtgctt ctttttgtag caaagtctca tccaaaagag cttgataaat ataagctctt
    85921 ccttgccgat aagatgttaa aagatttttt ttaactagcc taccaatgag ggtcttaata
    85981 gtggaatctg accattgata ttttttcctt aaaatagtaa taatatcgct acttttaata
    86041 tcaccactgg cccacaccac acgcatgact tcccattcgg cagctgatat ctgttgcata
    86101 acgtcacctt cattcacaat atatttacgt ttgtaaatta attataacga atttaactac
    86161 atttgtaaat aaataacttt tctcattttt ctatccttat attgacaaat gaatcgtttt
    86221 tactataata ttattgcaat aaaaataaca tttacattaa ggagataccc ttgaaacatc
    86281 ctattcgaaa aacacttgtc gccttaggtc tattactgac cttatgcctg ccaactccag
    86341 ttgcagctag ttctcgttct tggaaaagct ggtttatcga gcagtatttt tggttaaaac
    86401 gtgataagag ttactattct aaacaagatg atccaagctt ccaaagatac cttgatgcct
    86461 gtcgtgaaca atctgataaa ccttatcaac tagatactaa tttagtcaat ggtccccttg
    86521 ttcaagaaaa tctttatggc atgcaggttt actcttggaa tgataatgga aaacctgatc
    86581 aaaaaacaat tatttatctt gccggtggtt cttatcttaa caatccaacg acataccata
    86641 ttaatatgtt aaagacatta tccacaagtc ttgacgctaa aattgtttta cccatttatc
    86701 ctaaagcccc acgttatacc tataactata ctatgccaaa attggtcaat ctttaccaac
    86761 actattacca taaaaatcag aatgttttcc ttatgggaga ttcagcaggt ggaggtttag
    86821 ccttaggtct agctcatgcc ctacacaatg aatcagtccc tcaaccaaag cagctcgttc
    86881 ttttatcacc ttggttagat gttactatgt cacacccaga gattccagaa tacgaagatg
    86941 ctgatcctat tctatcttct tggggattaa aacgagtggg agaattgtgg gcttactctg
    87001 ctgataatac caaccatatt tatgtcagtc ctaaaaatgg tccgatcact tatctaccac
    87061 caattacttt atttactggg acacgagaga tcttttatcc tgatattcgc gattatgccg
    87121 caaaactgaa agccgctaac cacaatatta cctttattac ccaagaaggc atgaaccacg
    87181 tttacccaat ttatcctatc gaagaggcaa aaacagctca ataccaaatc attgatgcca
    87241 tcaacaaaac tccttaatga ggggaataac tcctacctgc caccagttaa tctggtggtt
    87301 tttttgtagt ttgcaccaca aaataacaat taaaaagagc cctatcataa tgataaggct
    87361 ctttctgtca taacatccgc accgcaatac ttaggatttg ttgtcaagat ctcgtaagag
    87421 ttgatcaatt ttattaccat aggcgatgga attgtctttt tcaaacacca aatctggaat
    87481 tttgtacatg gtcaattgtt tgccaagttc acgtttaatc gttccagtcg ctttttcaag
    87541 ccctgtttgt gctttttgat tatcagatgc caagtcactc ataatagtgt aataaacttt
    87601 agcaagtgac aagtcaccct gcatttgcac ttctgtaatc gttactccct gaacgcgtgg
    87661 atcacgcact tttttctgaa gaatatcatt tacttcgcgc ttgatttcca tcccaacgcg
    87721 gtcaatacga tgattagcca tagccatttc ctttccacat ttttaaaaca aaagctaggc
    87781 tgaaagccca gcttatgaca ttgctacctg ttttgataac gacaattaaa gggaatctga
    87841 gaattccatg acgagactgg aaggaatgcc ccaagtagct catctggtag aaaaagtcat
    87901 tatttccgac agaggaaaaa cgttacatct cagaccttct taacccctat tttctcacaa
    87961 tttcttccat aatataggct tcaatagtat cgtcaacttt aagatcgtta aagttttcaa
    88021 tcatcaaccc accttcttga gcattaccga cttctttaac gtcatctttg taatgtttca
    88081 agctggccag tttaccatca aaaataacga cactatcacg gataacacga acactcgaat
    88141 cacgtgtcac cttaccgttg attaccataa agccaccaat tgttcccact ttagaaactt
    88201 tgaaggtttc acgaataatg gcttcaccaa gaattttttc ttggtaaaca gggtcaagtt
    88261 tccctttcat ggcttcttct acttcttcaa tgactttata gataatgcta tgaagacgaa
    88321 tttccacatc atccgtatct gcttgttgac gagcttgtgg ggtagggcga acgttgaaac
    88381 cgataataac agcatttgat gcttcagcaa gggtcacatc agactcattg atagcaccta
    88441 cagcagagtg aacgacattg acacgcacac cttccacttc aatctttaca agagatgctg
    88501 caagggcttc aacagaacct tgaacgtctg ctttgatgat gacattaaca gtcttgattt
    88561 ctcctgcttt aagggtatca aagagattat caaggctaac acgctgtgta ttttgacgtt
    88621 gtttgaggag ggcacgtttt gatcgctcct caccagctgc acgcgcagct ttttcatcag
    88681 cgtaaacagc aaagtgatca ccagccattg gtgtttcgtt caaaccagta atggaaactg
    88741 gtgttgatgg ctccgcagat ttaacacgac gcccaaggtc atttaccatg gcacggacac
    88801 gaccaaaggt attaccaaca acgattgggt cttgaacatg aagagttcct tgttggacaa
    88861 gaagcgtagc gatagcacct ttacctttat ctaagcgtgc ttcaatcaca gtaccaatag
    88921 cacgaaccgt cggatcagct ttcaattctt ctacttcagc aaccaaaagg actgtttcta
    88981 atagttcatc aatattttta ttaaatttag cagatatctc tacaaattcg cactctccgc
    89041 cccaagcagt tgagatgata ccatattctg ccaattctgc gataacacgt tctggattag
    89101 cacctggttt atcaattttg ttgatagcaa caataattgg aacaccagca gcttttgagt
    89161 gattgatcgc ttcaatcgtt tgtggcataa caccatcatc agctgcaaca atcaaaatgg
    89221 tgatatcggt aacggaagct ccacgtgcgc gcatgcttgt aaaggccgcg tgtccgggag
    89281 tatccaagaa ggtaattttc ttgccagctt cttcaatctg gtaagcacca atatgctgag
    89341 taattcctcc agcttctcct gttgccacac gtgagttacg caaagtatca agcaaagttg
    89401 tcttaccgtg gtctacgtgt cccatgatag ttacaacagg tgcgcgttct acaatatttt
    89461 caggattgag gtaattttca tcctcaaaga agcgctcgat atcagcatca tctacttcta
    89521 ccttagcctt agcctcaata ccataatcta ccatcaataa ttcgatagta tccccatcta
    89581 aagactggtt ttgagttgcc ataacaccca tcataaacag ctttttaaca atttcagcgg
    89641 gttcgcgttt gatacgtttt gcgatttcgg caactgtcat gccttcagta tattcaaatt
    89701 cttttggcaa ttcatggaat ttacgctcgg ttactggttt tggaacggtg ttggtattct
    89761 taacattttt gccttttttg gtctttttat ttttattcca gttactattt ttttgatttc
    89821 tcacttggtt ttgactattc caactcttct tatttttctt ttgtccttct tgtgaatgat
    89881 gagttaactc acgattcttt tcaggacgtg cttgtttttt acggcgatta tcagcagtag
    89941 atttagcact aatatttgat gactttaatt tagtttctgc ttcttcaata gatttcaatg
    90001 ctgcttcacg atggctcatc tcctcagctt gtgcttttag agccgcttct ttagcttctt
    90061 gtcttgccaa ctcagctaaa cgcttagctt cttgctgtgc acgaaaacgt gtttcacttt
    90121 ggcgtgagta ttcagcattt tgttcagctt ttaaggcagc agcacgagct ttgaaatcaa
    90181 ttttaggact tttcgattga ggctcttgtc gtccttgctt tttttggttt gtgaatcgac
    90241 cattcttgtg attctcctta gcaaaggaac ggttacgatc accaactagc tgatgattat
    90301 catgtctagg tgatacattc gatgcttttc gctcaatacg cttatcgttt gtatcacctt
    90361 gagaacgatg ggtaatcctc ttatctcctt gttcgttagt ttgatgatta ttgggctggc
    90421 gataacctcc tcgacgttct tgagaacgat gagaagagcc atttgcttgt tttcgagcag
    90481 cctgttcctt tgcacgagcc tctctttcag ctttaaaatt acgactcttt ggcttagaga
    90541 cctgtgtttt ctctacatgc tcagaacctg tttctttgac cactgttaca gagggttgag
    90601 caacttcttt gggtttgact gtttgagaag ctgtcacatc aggtttagaa gcctttgaaa
    90661 aacttgaaat aatctttttc gcatccgctt cttcaacact tgatgcatgg cttttcacat
    90721 ctaatcctaa gtatttagcg tgttcaacca cctctttact acttttacca atttccttgg
    90781 caatttcatg taatcttttc tttgacaatt tgtgtcctcc tattcatcta ttccataaga
    90841 gtcctcattt tctttgaaaa tccagcatct gcaatggcag caaccttcct tggtttacct
    90901 agtgcagcac ttaattccag tgcattcaac actgtggaga cttctacatt ataataatta
    90961 cttttatctg tcactttttt tgtcacatta ggaccagcat cattggctaa aaatactaat
    91021 attacctgct ggtgttgaat agcttttact actagttctt cacctgaaat cacttttcca
    91081 gcccgttgag ctagaccaat aagactagat aatctttcta aattagtcaa gacctaactc
    91141 tcttcttttg attttgtgat caacataagc aatcaagtca tcgtaaaaac tttctggaat
    91201 gtccattgag aaactcctgt tgaaaacttg ttttttcttg gccattaagg cctcttgatt
    91261 gtctaatttg atataagcac cacgaccatt ttgtttacca gttggatcaa tgaaaacttg
    91321 accatcctta gtttttacaa tcctaagaag atctcgttta gcaataattt caccagaaac
    91381 aagtgatttt cgtaaaggta tttttttgac tttagacatc aaacacctct tttcttatac
    91441 ttcctcggca gtcataacat cgtcaacaac tggctcttcc acagctgttg ctgcttcttt
    91501 ttccgcctca agacgatcat attcgctagc tgatttgata tcaatacggt agccagtcaa
    91561 atgtgccgct aaacgaacat tttggccgcg acgcccgata gctaatgata atttgctatc
    91621 aggaactact accgtagcac gtttaagatc ttcatcgtca aaaagtacca tgtctacttc
    91681 agccggagca atggcattgt agatgaactc agctggatca tctacccatt gaatcacgtc
    91741 aatattttct tcaactggaa tttcaagccc cgtcttagca tctacacgtt ttggatggaa
    91801 cttgctgatg acctttttaa tattacttcc accacgtcca acaattgttc cgatggcatc
    91861 aacgttagga ttatgactgc gcacagcaac cttggtgcgg tcacctgctt cacgagaaac
    91921 actcatgatt tcaacagtac catcaaagac ttcaggaatt tcttgctcca taatacgttt
    91981 gatgaattct ggatggctac gactaacaaa gacgttaact cctttaggat tattttcaac
    92041 tttgtagaca taaacgtcaa tacggtcatg tgatttgaaa gtttcacctg gaatctggtc
    92101 ttggtgagac aattgtgctt ctaaggaacc aagattgaca taaataaaac gttgatcaaa
    92161 ccgttcaact gttcctgtca taatttcacc ttcatgctct ttgtattcat tgaacatcac
    92221 ttcacgcatt tggcggcgca tcttttccat aatagtctgt ttagctgatt gagctgcgac
    92281 acgtccaaat tcattgacag attcttcaaa gcgaatctta tcacccaatt cataggcaga
    92341 actgatagca agagcatctt tcaaactaat ctcaagccgg ctgtcaaaaa cttcttcaac
    92401 aacctcacga accgtaaata cttgaaaatc agctgttttt tcattaaatt caataacaca
    92461 tgattctgat tgaccatagc gacgtttata ggcagacttt aatgattctg tcactgcgtc
    92521 aataatatct gctttatcaa tgtgtttttc ttcttccaaa atacggaagg cttctagcat
    92581 ttctttgctc ataatgttat ctaccttgct tgtaaagctt ggcaaaaatc ctttcttaaa
    92641 ttaatacgat caatagcccc ctaaaggctc ccttaattcc ttttgtttag cttgtataaa
    92701 ctctataggt gttgtttcaa atttgcttaa atgttcctaa aaaagtttag tgctttgaaa
    92761 taaaagttat aatttgacag ccattctcac cttagcaact gcttgatatg gtatattcac
    92821 gatcttatga cgtgttttat caagataatc aatggtcaac gtttcaccat caaaggctaa
    92881 taagtctcct tgaaaaactt tcaccttatc aatagcttga taaagactca cattgatata
    92941 agagccaact gctgctttta aactgtcagc tgtcttgagc ggacgctcca aacctggact
    93001 agagacttct agcatatatt ggtttggaaa aggatctgga tcaatcgtat ctaacagcgg
    93061 actaataata ttcgtcaagt cagatgtatc ttccactgtg attccacctt ccttatcgac
    93121 taaaatacta aggatgtagt cactacccat tttgtcatac tcaacgtcta ctaattcata
    93181 aggtgcctta atctcaggcg ttactgtctt ggttacgata tcgataatag atgtatttgc
    93241 tattttgatt acctcctcta tttttatgct cttctctaag ataattggtc cttgggaatc
    93301 cacttaatac aaaagtggcg agacatatcc caccaccttt ctgtattatt taagtctatt
    93361 ataccataat ttaagaggaa tgcaaggata tgcactttgt tttactcaca aggagaggag
    93421 gggattcgaa cccccgagcc ccgttaagga ctacacgctt tccaagcgtg cgcactaagc
    93481 cactatgcga cctctccatt actaaagaag ttaatactgt atcaactcct ttatgttatc
    93541 atattttgaa acaaaatact actagaaatt tgcctcaact cggtaaatga cttgaccttt
    93601 attagagaac ttctcttcat attctgtcat gacatttcct tcatagttac tagcgtgtaa
    93661 gtcaagccag atctgtctca aggtcatgcc gtattgagaa aaactagcta aactgtactc
    93721 aaacaagccc cgattatcgg ttttaaaatg aatttcaccg tgttctggca agatacgctt
    93781 gtaagtgtct aagaaatcct tgtaggtcaa acgacgtttt tcatgcttgg tttttggcca
    93841 aggatctgaa aagttgaggt acatcatatc cacctcacca tcttcaaaat agttggttaa
    93901 acttgatcca tccactcgca gaagtttgac attgggtact tctgaagcta ataccttatc
    93961 caaggcgtag cttaggacag ataattgaat atcaatgcca atgtagttaa tatcaggatt
    94021 tttcaaggcc atccctgtga taaatccgcc ctttcctgaa ccaacttcga tatgaatagg
    94081 acggtcattt ccaaaaacgt catgccaacg gcccttggca tcttctggat ttaatatcac
    94141 atagtgtggg ttattagcta agtgctcctc agcacctttt cgttttctaa ctcgcattat
    94201 ttctttctaa atatttctct aaattttctg agggcataaa tctcctgatt cacatgctcc
    94261 atgtcacgct tgtcaaaaca cttgagaatt tgtgtcaggt gagaaaattg accataccaa
    94321 ataatttttt gcataacctt gtcattattt ttatagccat aataagacag ccattctgac
    94381 caacgagacc gtggaatata gtggctcaac aggtaagcaa catcatacat ccgatcagtt
    94441 agacgaacag aatcccaatc tactaaaaaa atcataccac tagtagtaat cacccaattg
    94501 ctatgtttaa tatctccatg cacaatcgtt gctacttctg atttgaactc tggtaagctc
    94561 cgttttaatt ctttaacgat agcttgtaag tatgaatttt gctgaatttg caagggtgca
    94621 ttttgctcaa aatcaaccaa taaatcgtat gggttttcaa tcttataatt gagctgaagc
    94681 agttgattga ctaatttttt agatttgtga aggcgcaata gaatatgaat gatttgctta
    94741 ctgttcatat cttctttggt caatgtacgg ccgttaagcc attcttgggc actcatcata
    94801 tcaccattgc ccatgcgttt ggcccaaagt aactgtggcg caatctgttc ttttgctaag
    94861 gcaggtagaa taggggtcgt atttaatttt ataaagacac attccccatt tggataagtg
    94921 cctttataag ctttgccact tttcccacgt aagggagtca aggtaagttc ttgttccgtc
    94981 gttgtcacct tatcgccctc cttttctatc ttttatagtc gtttacccct attttacttg
    95041 ttttaggcta cttagtcaat gatcttcttt aacttataag gtagatatat acaagctatg
    95101 aaaaccatac ctacaatcaa catgagtgct tttggcgctg atgagcaaca cagcatattg
    95161 acgattaaca ttaaaaagct taaacctcgt aaaaaactta acatattttt cttcttgctc
    95221 cgactatttt caggataaag actagtcata taatggtaat cgtagtgata ataaagggaa
    95281 agtaattgga atacaactaa atagttaaaa atgagtgcta aacttactga caaataaaga
    95341 ttatggataa aaaatacaga taatgagctt aatagcatta gtcgtaaaaa taagcccaaa
    95401 taatctgaac tacgtaaaaa ggctctagca taaagggaca gccaaaggtt tgaaggagtt
    95461 tgcttaacta attttaaaag aggatttaga taagttcttt ctttcacttt tgtagaaatt
    95521 cctttgactg ttgtaaaaag agaataaaac tttaaaatac tttgcttgcg attgctttca
    95581 aatgcgacag cttttgccca atctaaacga tttcctctca aaaaatatct tgtctttcga
    95641 ctaagcacta ctctttttag tgccaataat atcaaaacta agataataaa aataaataaa
    95701 gacagaccta aacgtctaaa aataggatat aaaaagagca atacagcagt ctgcaaagtt
    95761 ccccaaagca aaaaagagag tcgctcagct tgtttgatat aagaaatcac ttcttcttct
    95821 tttggaagta agaaatgctg atctgcctct tctagatacg ttgctataga tcccatactg
    95881 agcaataatg ggatcaatat cccaagacaa acctgaatag gtagatgatt cgttggaaaa
    95941 tggtttagta gctgaccata ctgcaccata gcaaagccta ataaaaacat caacaccaaa
    96001 acaaagtgat catttaagac gtaacgaagg tatttgtttt gttgtttttg aaagtcttga
    96061 cggcgtttca gaaataatgc tttcatactt aatcctcttt tgttaatgca agatagatat
    96121 catttaagct cgctgaacgg tcaccaaaag cttcttgcaa gtcagcaaga gttccttggg
    96181 cacgaacttg tccatgatgc aaaatcacaa aacgatcaca cattctttca gcagagtcca
    96241 aaacatgtgt actcatcaaa atagattttc cttttgcttt ttcgacttct agcgtttgga
    96301 ttaagtctga aatagctaaa gggtctaacc ctaagaatgg ttcatcaaga ataaatagac
    96361 ttggatcaat gacaaaggca caaataatca tgactttttg tttcatccct ttagaaaaat
    96421 tgacaggaaa ccattcaagt ttgtcagtta aacgaaacat ttccaagaaa ggttgtgctc
    96481 gtttttgtgc cacttctaag tcgatatcat aagccatagc tacggtgttg atatgctctg
    96541 ataaggtcaa ttcttcatag agactaggag tttctgggat aaaacctatt ttttgacggt
    96601 aggcaactgc attttctgct agagttaaac catcaataga aatacttcct tgataaggct
    96661 tcaaaaagcc aataatttcg ttgatagttg ttgactttcc agcaccattt agcccgatca
    96721 aaccgactaa ctctccattg tctacagaaa atgagacatc gtttaaaaca gggatattgt
    96781 gatatcctcc tgttagattt ttaatgttta acatataatt tctttctagt ttttgatata
    96841 cttataatat attataacaa attcaagtag agaaggtgat ataaaatgga aaattgtatt
    96901 ttttgcagca tcattcaagg ggatatcccc tcttcgaaag tctacgaaga tgagcaggtc
    96961 ctcgcctttt tagatatctc acaaactaca aaagggcata ctctagtcat tcctaagcaa
    97021 catgttcgta acttactaga gatgactgct gagacagcta gtcatctctt tgctcgtatt
    97081 cctaaaattg ctcgtgctat ccagtcagct actggcgcta ctgccatgaa tatcattaac
    97141 aataacgaag ccttagcggg acaaactgtt ttccatgctc atgttcatct cgttcctcgt
    97201 tataatgaag aagacggtat ctcaattcaa tacaccactc atgagcctga ctttcctgtc
    97261 ttggaaaagc tcgcccgaca aatcaatcag gaggttagtt catgaaagtt aaaaccgtga
    97321 tagccgtcgg attattatct tttaccgctt acaaagcata tcaaaaacgt tgtaccataa
    97381 aagagctgtt atccatcagt agacaagcaa aagatgctgc ccaacttgat ttagataaca
    97441 ttaaagcaaa ccttgacctc attcacagtc aaggaaaagt aattcaaaat attagtcagg
    97501 acttggccca taaatggcgc tactttaacc aagagacaca agcacacctc actgaaatcc
    97561 aaaatcgtat ggccaaatat caagaagata gtgagctaat ttctagtgaa tcacctactt
    97621 gccaaaccgt cattttaact aacaaccatt ccagatagta ttatctccct catatacttt
    97681 atttgaaatc acagacagct atcatctttg atacctgtct tttttatatt caaaatcgga
    97741 tattttaaac ataaaaaccc tcagaacgtt aggtctgagg gttgatatta gcaggaggaa
    97801 ctaatgatcc agaccctgat gagctagact catcagctgc taaagcatct gatgaagaag
    97861 acggcgtagc tggcgtatgg cttgaagcag tagagtcctg gtctgtacta gcactctggc
    97921 cggtatctac tccacttgaa taattagcgt aagagctatg actatcagaa taagatggag
    97981 cctggcctga agagtcatag ttgttgttta ctgtctgaga cttagttgac ccatacagat
    98041 tttcataaac agtagcattt gtttttaatt gactaacctt atgaagtcct aattctgttc
    98101 ggatacgatt ttggatttct aacaaatgat tagaggtaac aatttggtat gatccaccat
    98161 ctgataaagt ggcatcttct ccttttagtt gataagtctt aatagttcta agtgcatcac
    98221 gataacctaa tagactaggg atagtgcgag aagagatttc gatattcgtt tgcatattac
    98281 tacttacagc agataaaatc ttccgataag agctaatgct atcaagagca aggatttttt
    98341 tcaatacctt ttgaatgact tcacgttgac gcttttgtcg accataatct ccctcaggat
    98401 catcataacg catacgagca taaaccaaag cttgttcacc gttaattttg tgtgttccag
    98461 gcgcaacagt agcttgatat tcaggttcgt tttcagcaat cgagatagga aaatcaaact
    98521 catttgtaac tgtaatccct ccaactgcat tcacaagatc aataaggcct tgcatattaa
    98581 tttgaacata gttatcaatg gtgatattca aaagatcttg cacggtcata atagccatct
    98641 gagcgccacc tgctgcataa gcagcgttaa gcttagcttc aacaccattc atttcattat
    98701 ttttgggtcc agataacgtg gttaaggtat ctcgttctaa actagtcata gttgttttct
    98761 tggtctttgg attaaccgta accaaaatca tcgaatcact gtttccttcc cacttggagg
    98821 cacgctctga agagcctgta tcaacaccca tcaacaagat agaaaaagct cttgtttgtt
    98881 taatggcatc acttttcttt gaagatgtcg aaaaatcttt aaaggtcttt gataattcta
    98941 ctgttgagaa ggtataagca ctagttagat agacacctaa tgccaagaca gttgttaaca
    99001 caatagctgt gaacattaaa actatttttt ttccaatttt catcgattca cttactgact
    99061 tacagattta cgcatatgat aaacatctaa gtcatctcca ttttttgatt tgatgtcgtt
    99121 ttttcgcata ctttcaatac gaaaaccata ctttttatac aggtaaatag ccttagtatt
    99181 tcttacttga acgtccaact taaggctttc gatataaggg ttttcttcag cccaatcaag
    99241 agcaatctct aacaataatt gaccgatacc ataaccacgg taagtcttag caactaacat
    99301 aaatacatct gcttcagctt ggccttggga taatacttcc ccagaaagat ttaaaagccc
    99361 tactactttt tcatctaatc tagctagcag gcaaaaatca ataaaagagg tttgacttct
    99421 tgataaaaag tctgacaatt cttgaggagt agcctctaat atagtctcta cgcctgttat
    99481 aaaatctgtt tctttggcag ctgccgtcac taaggaaagt acagcttttg catcttgagg
    99541 tacgccttct tcaataacga gactttgctg aatcatgtga cattatctcc agaagctgac
    99601 gagagcgctc accatgcgct aacaagtcta gttgacgacc tttgtctcgt ttagtaatgg
    99661 taatttgcaa atagtcttgt aataatccct ctcctaataa ttctccccac tcaataacgg
    99721 taacaccatt accaaaaaga aaatcatcta aatcaataga gtctggatca tcaccaacac
    99781 ggtaaatatc taagtgataa agaggtagac gtccttcata ttctctaaca atagtataag
    99841 ttgggctttt gatcatttga ctaatcccca tccctttagc aatacctttt gccaatgttg
    99901 ttttaccggc acctaagtcg ccagacaata caatcacatc tccaatagac aaataagtac
    99961 ctagggttgc tccgtaagct ttaagagtat attcattttc actataaaac atagcaacat
   100021 tatatcagaa aaaaaacata cttccaagca ctacctagaa gatgactcaa ataaggtatt
   100081 cgtaaagtaa aaacgcttct ttatattaaa tgttaaaatc aactaaagaa gcggcagtta
   100141 gtagcaaaat aagtaaatta tttggttata agatagttaa tatgatgaaa tttacaatga
   100201 acaagaaggt tgctccccaa ataatagggt gaatatcttt tgtttttccc tcaacaactt
   100261 ttaccagaca atagaaaata aaggcagcgg caataccata ggaaatagag taacacagcg
   100321 ccataaagaa agctgcaaaa aaagctggaa gagcatctgc aaatttactc caattaacat
   100381 caagaaaaga agacaccatc atgacaccca caacaattaa agctggagcc gtagcagcag
   100441 ctgggacaat acctacaagc ggtaatagta atattgataa taagaagcat actgcggtgg
   100501 agactgctgt tagtccagta cgtccacctt cagcaattcc tgctgctgat tcaacatagg
   100561 tagtcgtatt tgaagttcca accaaagccc caatagaagt accgatagca tctgcaaaaa
   100621 gcgcacgatc catttttgaa ctaaagccta tactattttc caaagcattc tcatcgtctt
   100681 gagagaaaat acctgttcga cgaccagttc cgataaaggt accaattgtg tcaaaagtat
   100741 ccgatagact aaaagcaaaa atagtcatga aaactagcgg taaacgactt gaatcgctaa
   100801 aaagagaact caaaccatcg aaagctgcaa ggaaagttgt acctaattca gtccaagctt
   100861 caccaatatg gctgatccca aaattgaggt tggacacatc cactatccct aaaggaatac
   100921 ctacaagagt tgttgcgaca ataccaatta aaatagcacc tctaaaattt cgaatcacaa
   100981 gagctgtcgt taaaagtaaa ccaaaaatag caagtaatac actagaatcc gtaaaactag
   101041 aaatcgtagg tacaactcca ccattggcgt ctacaaataa tagaccatct gcaaatgttt
   101101 tagccgatgc tttagccggt tcaacaccat ttaccattac tatattttca gcagagatag
   101161 aaaaagtaat gatatttgcg tttttaaatc ctaaataagc tacaaagaca ccaattcccc
   101221 caccaatagc atgctgtaaa ctaactggaa tcgccttgat gatactttta cgaaacttgg
   101281 ttacggtaat aaaaatattg aataatccac aaatgaaaac cattgccaag gcttcttgcc
   101341 atgaaaagcc taaagcaaaa acaactgtat aagtgaaaaa agcgttaagt cccattcctg
   101401 gtgccagcgc ataaggcaca ttggcaaata atcccataat taaggttgat atggctgctg
   101461 cgataatcgt agccaaaaag acagcattag agggcatccc cgctgcacct aaaatacttg
   101521 ggttaacaaa caaaatatag gacatggcaa aaaaggtcgt taaaccagcc ataatctcag
   101581 ttgagacagt tgtcccattt tcgcttaact taaaaaactt ttccattgaa atggagtctc
   101641 cttaattaaa tagtaggtaa aatcaaaaag cgcttatcac tagataagtc tttttgacac
   101701 ctcattatta ttgttattgt tcgtattaaa atgaacaata acactatgtt accatttttt
   101761 tgttcacttt tcaacgtcta taacttcatt tattcattaa aaaaacagtt atcctatctt
   101821 ttttactaat gaatacgctt aacttatctt ttctctttat cttggagcaa aatttgctat
   101881 aatttaatta tgactaaaaa attgattgcc attgatttgg atggaacttt gttacaccat
   101941 gacaacacca tctctaccta tactcaaaaa accatcaaag ctgtccaaga caagggccac
   102001 cacgtcatta tttcaacagg ccgtccttac cgcatggcac tgggctacta tctgcagctc
   102061 aatttaaaga ccccaatcat cacttttaat ggggccttga cccacatgcc ggaacaaaaa
   102121 tgggcctatg aacataatgt cactttggac aaaggctacc tactaaggtt actacaatat
   102181 caggatgatt tccagatgga ttttattgcc agtgagtatc gaaaaaatgt ctacatcacc
   102241 atgaccaatc cagaaagtat cgacccgcaa ctctttggtg ttgatgaaat tactcaggac
   102301 atggcattag agattaccaa aatcactcga aatccaaacg ccttattgat gcaaacgcgc
   102361 cacgaagaca agtatgcctt agctaaaaac atgcgtgctt tcttcaaaga tgaaattgaa
   102421 attgattctt ggggaggccc tctcaacatt cttgaaattt cgtctaagaa tatcaataaa
   102481 gcttacgctc tgaactatct ccttggaatt tacaatatgg ataaaaagga tttaatcgcc
   102541 tttggtgatg aacacaatga cactgagatg ctagcttttg ctggaactgg ttatgctatg
   102601 aaaaatgcta gccctgtgct actgccttat gctgatcagc agcttaattt ttccaacgaa
   102661 gaagacggtg tggccaaaaa attggaagaa cttttcttat agtagcaaac gaaaccacta
   102721 tttttcagaa aatggtggtt tttcttctgt caacagctat caaaaaatga aaatcatttt
   102781 aataatttca acatttttca gcatattttt gttttaaaca gcttgaaaac acctttaata
   102841 tcaataatct gcctatttaa tcctaaattc tgaaaatttt ttcatgtttt gtactatttt
   102901 tccgaaaggg cttgattttt tagtgaaaac gttttaaaat agaaacgttc ttgaatttcg
   102961 tttaagtgaa aaagaattgc caaaatttag ttttggaagg agattattct tcttcatttc
   103021 aacgaaaaat attttaaagg aggaagaaca agaatgggta tcggtattat tattgccagc
   103081 catggtaaat ttgctgaagg tattcatcaa tctggttcta tgatttttgg tgaacaagag
   103141 aaagttcaag ttgttacttt catgccaaac gaaggaccag atgatttgta tggacacttc
   103201 aacaatgcta tccaacaatt tgatgctgat gatgaaatcc ttgtgctagc tgacctttgg
   103261 agtggttctc catttaacca agctagtcgt gtggcaggtg aaaatcctga ccgcaaaatg
   103321 gcgatcatca ctggtctcaa cttgcctatg cttattcaag cttacactga acgtcttatg
   103381 gatgctggtg caggtgttga acaagttgct gcaaacatca ttaaggaatc taaggacggt
   103441 atcaaagccc ttcctgaaga ccttaaccca gttgaagaaa ctgctgcaac tgaaaaagtt
   103501 gttaacgcac ttcaaggagc tattcctgct ggaactgtca tcggagatgg taaattaaag
   103561 atcaatcttg ctcgtgttga cactcgtctt ttacacggtc aagttgcaac agcatggact
   103621 ccagcttcta aggctgaccg tatcattatt gcttctgatg aggttgctca agatgacctt
   103681 cgcaaacaat tgatcaaaca ggctgcacct ggtggtgtca aagctaacgt tgttccaatt
   103741 agcaaattga ttgaagcttc taaagatcct cgttttggta acacacacgc acttattctt
   103801 ttccaaaccc ctcaagatgc ccttcgcgcg gttgaaggtg gtgttgaaat caacgaattg
   103861 aacgttggtt caatggctca ctcaactggt aaaacaatgg ttaacaacgt tttatcaatg
   103921 gacaaagaag acgttgctac ttttgaaaaa ttacgcgacc taggtgttac attcgacgtc
   103981 cgtaaagttc ctaacgattc taagaaaaac ttatttgagc ttatccaaaa agctaacatt
   104041 aaataagttt caaacgctat aaggttttaa aacgatgact agctaactta ttagcaaaaa
   104101 gtcctcgttt actatacttt gaaaggatta caacatgtca gatatttcga ttatttctgc
   104161 aattttggtc gttatcattg ccttcttcgc tggtcttgaa ggtatcctcg accaatttca
   104221 aatgcaccaa ccacttgttg cctgtacttt gattggactt gtaactggac accttgaagc
   104281 tggtgtcatc cttggtggta cacttcaaat gcttgctctt ggttgggcaa acatcggtgc
   104341 tgccgttgcc cctgatgctg cccttgcctc tgttgcagct gctatcatca tggtcaaaag
   104401 tggcgacttt actcaaaaag gaattacctt tgcttactca acagctatcc cacttgctgt
   104461 tgctggtctt ttccttacaa tgatcgttcg tactttgtca actgcccttg tacacgctgg
   104521 tgacaaagct gccgctgaag gtaatttcgc aggtattgaa cgcttccact ttattgccct
   104581 tcttcttcaa ggattgcgta tcgctgtccc agcagctctt cttgttgctg ttcctacttc
   104641 agccgtacaa tctgttttga atgctatgcc aaactggttg aacgaaggta tgcaaatcgg
   104701 tggtgcgatg gttgttgctg taggttatgc tatggttatc aacatgatgg ctactcgtga
   104761 agtatggcca ttcttcgccc taggttttgc tcttgcagct atcagccaat taacccttat
   104821 cgctatgggt gttatcggtg tagcaattgc cttcatctac cttaatcttt ctaaaaaagg
   104881 tggtaacggt ggtaatgcag caggttcagc tgatccaatc ggcgacatct tagaagacta
   104941 ctagaaaggg gtaagaacaa atgactgaac aaattaaatt aactaaatca gaccgtcaac
   105001 gtgtttggtg gcgttcacaa ttcttacaag gttcttggaa ctacgaacgt atgcaaaaca
   105061 tgggctgggc ttatgcactt atccctgctc ttaaaaaatt gtatacgtct cctgaagacc
   105121 gtgcagctgc tcttgagcgc cacatggaat tctttaacac tcacccatac gttgcagctc
   105181 caatcattgg tgtaacactt gcccttgaag aagaacgcgc aaatggtacg ccaattgatg
   105241 acaaggctat ccaaggggtt aaaatcggta tgatgggacc tcttgctggt atcggtgacc
   105301 cagtattctg gtttacggtt cgtcctatcc ttggggcact tggtgcttct ttggcttcaa
   105361 caggtaacat cgttggtcca cttctgttct tctttggatg gaaccttatc cgtatggcct
   105421 tcttatggta tactcaagaa tttggttaca aagctggttc tgaaattact aaagacatgt
   105481 caggcggtat cctccaagac attactaaag gtgcttcaat ccttggaatg tttatccttg
   105541 cagtgcttgt tcaacgttgg gtatctatca actttactat cgaccttcct ggaaaacaat
   105601 tgtcagatgg tgcctatgtg gtcttcccag atggcgctgt taaaggtgct gagttgaaaa
   105661 ctatccttgc caacgctatt ggcggtatga gccttgataa agtccaagct caaacccttc
   105721 aaggacaatt ggactctctt atcccaggtt tagctggatt actccttaca ttcctttgca
   105781 tgtggttatt gaagaaaaaa gtttctccaa tcgcaatcat catcggcttg tttgcatttg
   105841 gtatccttgc tcaccttgca ggtattatgt aatcaaccaa tggaagtctg agatgaactc
   105901 aggcttcttt tttatgcttt atgtcagaaa aatcccactt aaaatatggt ataataacta
   105961 caactacgca atgaaaggaa ctaaaatggc tcaatcttta aacactagtg tcgaatacaa
   106021 gacaaaagct gtctcctacc ttggaatggg aggcaaagtt ggtcatattt tactcggtga
   106081 caaggccctt gaattttaca acgataaaaa tgtgaatgat tatattcaaa ttccttggac
   106141 agctatcaat cacatcgggg ctaatgtttc aagaaaaaaa gttagccgcc actttgaaat
   106201 ttttacggac caaggcaagt ttttatttgc ttctggagac tctggaaaaa tcttaaaaat
   106261 cactcgtcaa catattggta atgagaaagt gattacatta ccaaccttga tgcaaacctt
   106321 tattaacaaa ttttttcgac attaaaaaaa taatgcgcag tgccgattta tcatttcaag
   106381 aaaacaaaga atagtagctc taaattgcta tttagtggaa aagattccct catttgagtt
   106441 tactttttct tgttttttgt tataatagtc ctaacggata agtaatacct ttttttcatt
   106501 cagagagtct gtggatgctg tgaacagata gggaaaatga tatgaaattc taccgtgtca
   106561 tcaataaaat agagattaag tgcacagatt gtgaagctgg atggaaccgc gccaaagcgc
   106621 tccagcatct tcataagctg tgctttttct atcgtcagag aatcacaaga tccaactgtc
   106681 ttacttagcc ttgtttcact gacagctact aataactatc ttaaaggagc ttctgtatgc
   106741 tagatcttaa acgtatccgt accgattttg acactgtcgc tgccaaatta aaaaaccgtg
   106801 gtgtttctga agacaccctg acccatctta aagaacttga tgaaaaacgt cgtgctctat
   106861 tagtgcaatc agaaaaatta aaagcagagc gtaatattgc ttctgctgcc atcgctcaag
   106921 ccaaacgtca aaaagaagat gccactcaac aaattgctga tatgcaaaaa gtctctgcag
   106981 atatcaaaac tattgacaat caactagtag ctatcgacca gcaagttact gacatcatca
   107041 ctgttttacc taatactcct cacgattctg tccctattgg agctgacgaa gaagacaatg
   107101 tcgaaattcg ccgttgggga acgcctcgtg actttaactt cgaagttaag gctcattggg
   107161 atctaggcga agatcttgat attttagact gggaatgtgg ggcaaaggta actggtgctc
   107221 gtttcttatt ctataaaaat cttggtgctc gtttggagcg tgctctttat aacttcatgc
   107281 tggatgaaca tatcaaagaa ggttatcaag aaatcatcac accttacatg gttaaccacg
   107341 attccatgtt tggtacagga caatatccaa aattcaaaga ggacaccttt gaattagcag
   107401 ataccaactt tgtcctgatt ccaactgctg aagtgccttt gaccaattat taccgtgggg
   107461 aaatcctaga cggcaaagaa ttgccaattt actttactgc aatgagccca tcttttcgtt
   107521 ctgaagcggg ttctgcgggt cgtgacacac gtggccttat ccgcctacac caattccaca
   107581 aagttgaaat ggttaaattt gctaaaccag aagaatctta ccaagaacta gaaaaaatga
   107641 ctgctaatgc tgaaaatatt cttcaaaaac ttggtttgcc atatcgcgtc atttcccttt
   107701 gtactggaga catgggcttc tcagctgcta aaacctatga ccttgaagtc tggattcctg
   107761 cacaaaatac ctatcgtgaa atttcatcat gttcaaatac agaagatttc caagcacgtc
   107821 gtgctcaaat ccgttaccgt gatgaggctg acggtaaggt caaacttctt cacaccctta
   107881 atgggtcagg acttgctgtc ggtcgtaccg tagcagccat tttagaaaac taccaaaatg
   107941 aagatggttc tgttaccatc cctgaagtac tccgccctta catgggtggc gaaaccgtca
   108001 tttcacctaa ataataaact caccccagag atcattaaag tgatttctgg ggtttactat
   108061 tttaaagagc caccacatca cttgaaactc actacattgc ccctttaaca acacttttct
   108121 tcacactagt ttatcaaaag tcttattagt atacccattt ccttatttac aagactagtt
   108181 aaaaaccctt ttggaaaggc ctcccttagc ttgataaaca cgtagggaga ctccaaaagg
   108241 atgttgttaa tatttacgaa agcgttggta gcgctcatct aataattggt ctaatggctt
   108301 agcttgcaaa ctggttattt gttcgatgag gttagctttg atgatgtcaa cgatttcact
   108361 tgaaaaataa ccatgttctg ggataatacg atctactatg cccatttgat acaattcgcc
   108421 tgcggtaatt ttcatcaatt cagcagcctc tgtcgctctt gaaccatctt tccataaaat
   108481 agaagcaaag ccttctgggc taaggaccgc atacatggta ttttcaagca tccagacctg
   108541 atcggcaacc gctaaggcta atgcaccacc agagcctcct tcaccaataa tgatggcgat
   108601 aatgggaacc ttgagatcac tcatttccat caaattttta gcaacagcct caccctgtcc
   108661 tcgttcttcc gcaccgacac ctggataggc tcctgcagta ttgataaagg tgacaactgg
   108721 tcgtccaaat ttttctgcct gtttcataag gcgcaaagct ttacgataac cttctggatt
   108781 gggctggcca aaattccttg ccaaattatc ctgtaaattc ttaccttttt gaataccaat
   108841 gaccgtaaca ggttgtcccg ccaaataagc taagccacct acaatagcac catcatctga
   108901 aaaatggcga tccccatgca gttccataaa gtcatcgaaa ataaggttgg cgtaatccaa
   108961 agttgttaaa cgcccttgat cacgcgcttc ttttaaaact cttgatacat ctgtcattgg
   109021 ccacctccat gaaatgctac taagtgggca atcttgtctc gcaactctgt tcgtttcaca
   109081 atagcatcca caaaaccatg gtcttgtaaa aattctgctt tttgaaaatc atccggcaaa
   109141 ttctcacgta ctgtggtttc aataacacgg cgtccagcaa atccaaccaa ggattgaggt
   109201 tctgctaaaa taatatcccc ttccatggca aaactagctg ttaccccacc agtagttgga
   109261 tctgtcaaaa tagtgaggta aaagaggcct gcattagaat gtcttttaac agctgcagag
   109321 accttggcca tttgcataag gctcatgata ccctcttgca tacgggcacc tcctgaagcc
   109381 gtaaaaatca ccaccggcag gttttcttcg atagccaatt caaacaatcg ggtaattttt
   109441 tccccaacaa cagttcccat actagccata ataaagtgag aatccataat agcaagtgca
   109501 atttgttgtc ctttaaccat agctttccct gtcaaaacag cttcatgcag accagttgtt
   109561 tccttggctt tttgtaattt ttcctgataa cctggaaaac gtaacggatc cttggtttca
   109621 atacttataa ataattcctg gaaagagcct tcatcaactg ttaaggtcag tcgctcttgg
   109681 gcagaaatcc taaaattgta agaacaggtt gggcaaatct ttgccaatcc caaatctttc
   109741 ttataaatca tgtgcttaca agctgggcat ttcgcaaaga gttcatctgg aacttctggg
   109801 acattatggc tgacagatcc tttgagggaa ttattgggag taatacggat gtatttatct
   109861 tttttacgaa ataaagccat attttctcct aatctttatt gtaatgtggc aggaacgttt
   109921 ccatcaagaa agaggtatca taatctcctg caatcactcg cttatctgaa atcaaatcga
   109981 gctggaagtc tgtattggtg ataatgcctt caatttccaa ttcaactaag gcacgttgca
   110041 ttttcatcaa agcgtcaaat ctattgcttc catgaacgat gattttagca atcatgctgt
   110101 cataataagg aggaatggca tagccattgt aaactgctga atcaactcgt agtcctacac
   110161 caccacttgg catatacaag tctgtaatct ttccgggact cggtgcaaag ttaaaagcag
   110221 tattttcagc attgatacga cattcaatag catgtcccgt gatagtgatg tcttcttgat
   110281 taatcgccaa aggctgacct gctgcaattt tgatttgctc tttgacaata tccactcctg
   110341 tcacaaattc ggtgacagga tgctcaactt ggatacgggt attcatttcc atgaaataga
   110401 atttctcgct gtcttcgtcc aacaaaaact caatggttcc cgcattctca taggctacag
   110461 cttcagctgc tctaaccgct gcttgcccca tttcgtgtct gagggtattg ccaatagcaa
   110521 tggatggact ttcttccaag actttttgat tattccgttg caaggagcaa tcccgttctc
   110581 ccaagtgaat gatgttaccg taagcgtctc ctaaaatttg cacctcaata tgtctagctg
   110641 ggtaaattac tttttccaaa tacatggcgc catttccgaa agctcccaaa gcttcttgac
   110701 tggcagcatt gaaagccgcc tccaaatctg cttctgtctc cactttacga atccctttac
   110761 ctccaccacc tgccgatgct tttagcatga caggataacc aatcttattg gcaatagcta
   110821 aggcttcttg agcgttataa acttcaccat ctgaccctgg aataacgggc actcctgcct
   110881 taatcatttc agaacgagca ttgattttat cacccatttt atccataacc gatgcggatg
   110941 gaccgataaa tttaatattc atctcttcac acatggtcgc aaactttgag ttttcactta
   111001 aaaagccaaa ccctgggtga atcgcttggg ctcctgtcac aatagctgct gacaagacgg
   111061 aattcatatt aagataggat tccttggaac gggcaggacc aatacagata gcctcgtccg
   111121 ccaatatcgt gtgcagagct tccttatccg cttccgaata aactgcaact gtggaaatcc
   111181 ctaattctcg tgcagcacga atgatacgca ctgcaatttc accacgatta gcaattaaga
   111241 tttttttaaa cataagggtt tcttcctccg cagaacaatc attctcattg cccacaggca
   111301 aaggttaatg ttccacttgc tgctagcttg ccatcaactt ctgccctggc ttcaacgaca
   111361 gcaatggtac cgcgacgctt gataaaggtt gctgtcatca caagttgatc accagggacg
   111421 acttgttttt tgaacttcac tttatccatt ccagcgtaaa agaccaactt gcctttattt
   111481 tcttcttttg acaattctaa gacaccagct gtttgagcca aagcttccat aatcagaaca
   111541 cctggcatca caggatagtg aggaaaatgc ccgttaaaga aaggttcatt aatagtcaca
   111601 tttttaatgg caacgatatg gtcgtctgac acttctaata cacgatcaac caataacatt
   111661 gggtagcgat gaggcaaagc cgcttgaatt tctctaatat ccatcatttg atccgcacca
   111721 atccttgtcc aaattcaatg acatcttcat ttgataccaa aatttctgta atcacaccat
   111781 cacatggcgc tggcacttcg ttcatcacct tcatggcttc gataatcaca agggtttgtc
   111841 ctttttttac agtatctccg actgccacaa atggtggctt gtcagggcta gctgcaagat
   111901 aggctacacc gactaaagga ctttcaacaa tatcaccttc tgctacaaaa gattctgctt
   111961 gtggttgctc ctctacagga acatccttaa ctgatgctgg actagacgct tccgaagcag
   112021 ttggattcgg aacaagttgt acctgtggta caggcacagc atgttcttga tttgatgtcg
   112081 atgcattgag gtgttgttcg tttttactaa agattagctc accttcattt gttttgaata
   112141 aaaattcacg taggcttgag gtatcaaact gagccatcaa atctttgatt tcttgaatat
   112201 tcaacctact cctcccaaca tttgaaagct aatacagcat tatgaccacc aaatccaaaa
   112261 gtatttgaaa tggcatagtt gatagctgtt tcttttcctt ctccaaagat gacatttgct
   112321 tcgatatcct ctgataaagc ttgtgtccca gccgtcatcg gaacatagtt atgacgcata
   112381 gcctcgatag tggcaatagc ttcaatagcg cctgctgctc caagaaggtg acccgtaaac
   112441 gattttgttg aagacaccgg aacatcctta ccaagaacgg ctacaattgc ttgactctct
   112501 cctttttcat tagctggggt tgaagttccg tgcgcattga cataattaat agcactggct
   112561 tcaataccag cttcttgtaa ggctaagtgg atggctttac gagctcctaa tccctcagga
   112621 tttggagatg tcatatggta ggcatcgcag gtatttccat aacccacaat ttctgctaag
   112681 attgtcgccc cgcgttcttg cgcatgttct aggctttcta aaacaagcat tcctgatcct
   112741 tctcccatga taaaaccatt tcggtcttta tcaaatggaa tagagcttct gcttggatct
   112801 tcagttgttg agagagctgt taaactttgg aagccagcaa tggcaaactt ggttatggcc
   112861 gcctctgacc caccaactat catcacatct tgagtcccaa atttaatggc acgaaaggca
   112921 tccccaatcg catcatttga agaagcgcag gcagtattaa ttgatttaca tactccttga
   112981 gcttttaaag acatggcgac atttcctgca gccatatttg gtagcgcttt tggcaacgtc
   113041 attggcttca cacgttttgg ccctttttca tgtaagcgaa tcacctgctc ttcaatctcc
   113101 gcaattccac caatacctga agcaacaata acgccaaatc gatcggaatc aatcatctca
   113161 atatttaaat cagcatgatt aatagcctct ttcgctgcgt aaagagcata aagagaatat
   113221 ctatcgaaac ggttcaaatc ttttttcaca aagtatttgt caaatggaaa atcctgaatt
   113281 tcagcagcat tcttgaccgc ataatcagtc gtgtcaaatt tagtaatagg accaatacca
   113341 atttggccag ctttcagatt gttccaaaac gtttcaggat catgcccgat tggagatgtt
   113401 agaccataac ctgttaccac tactctttta aatgtcattt cactacgtct ccttattgca
   113461 ttgtcatacc gccatcaata gcgataactt gtcccgtaat ataatcttgt tccaccaaga
   113521 agcttgctaa gtgagcaact tcttgagctt ttccaatacg tttcattggg atttgactta
   113581 agatttgctc ttgcattttt tcaggaagga cacctgtcat atcggactcg ataaatcctg
   113641 gagcaatagc attcacgcaa atgttacgag cagcaacttc acgggcaaca gacttggtaa
   113701 aaccaatcat tcctgcctta gaagcagcat agtttgcttg cccaatattg cctgttaaac
   113761 caaccacact agagacatta ataattgctc cttggcgggc cttgatcatt ggttttaaca
   113821 ctgattgagt catgttaaaa gcaccggtca aattgatttt caagacgcgc tcaaaatcct
   113881 cttccgtcat tttaagcatc aatttatcat tagtaatgcc agcattgtta actaaaacat
   113941 caatcgaacc taaactttcg atagcttcat tgaccatacg tttagcttct gatgcttctg
   114001 aaacatcccc agagatggta acaactgtaa cgccgtagtc agtaaaacta gcaacaagct
   114061 cctcagagat agcagagcga ccatttaaga caatattagc tcctaaactg gcgaattgat
   114121 gagccattgc taaaccgata cctctcgttg agcctgtgat aaatatattt tttcctttaa
   114181 tttccatgaa tgtcctctct atctaaaaat aaacgtaagc ttaccatgtt ttcaacacta
   114241 gtacatagta aatttttatc aattttcttc acaaaacctg tcaaaacctt acctggtcct
   114301 acctcaatga attgtgttat gccactttct actaaagtcg caacactgtc ataaaaacga
   114361 acaggctcca tgacttgacg ggctaatagt tctgggatac ggtctttttc cataatatta
   114421 gcttcggtat taccaaccaa aggaatcttg aagtcactga agttgtatct ttccaactct
   114481 ttagccaaca agcggctagc tggttctaac aaagcagtgt ggaaaggacc tgacacgttt
   114541 aaagggatta aacgcttaac tcccctttcc tttaaaagtt caactgccac gttcacagca
   114601 tctgtctgac caccaattac aatttgacta ggagtattat agtttgctgg agcaaccact
   114661 ccatgtttag cagctatttg acagacttct tcgatgactt gcacgtctgt attcataacg
   114721 gcaaccatct ttccagatcc ttgtggtgct gcttcctcca tcaagcgccc tctcttagct
   114781 actaaggata gggtatcttc aaaagagagt gcccctgatg ctaccaaagc tgagtactct
   114841 cctaaggaaa gaccagctac catatccggt ttaacgtgat gtaagcccaa aacacggtaa
   114901 atagcaattg atgatgtcaa aataactggt tgcgtatagc tagtttgatt aagttttaac
   114961 tcgtcactat caatcaaacg gcgcaaatcg tatcccaata cttgactagc ttgatcaaag
   115021 gtttttctta caatagcaaa gttatcataa aaatcccttg ccatccctaa tttttgggca
   115081 ccttgaccgg caaataaaaa ggctgtcttt gtcattatca ttatccttca tgtgtttatc
   115141 tacttttcta ttgaaacaga ttgccagcgc ttagcttcat tttgaataac acgagctgca
   115201 ccataataaa tatcttttaa aatcgtttca cagctttctt cttttctcac aagccctgca
   115261 atttggccag ccataacaga tccattgact acatcgcctt caataacagc atgtcgaagc
   115321 gatcctgctc ccatttcttc aatatcagta gctgtttttt gaccaattaa aaatgctttt
   115381 tctgcttttg cgtaagctga ggtcaattta tttttaatag agcggacagg gtggcccaca
   115441 acctgcgcag aaatcactgt atcaatatct tttgctgcta agattttatc tttaaaattt
   115501 tggtgggcat tggattcttt agcaacaaca aagcgagttc caatttgaac agcctctgct
   115561 cctaacataa atgctgctgc tgcaccatga ccatcagcta taccacctgc cgcaatgaca
   115621 ggaatcgaaa ccgcttcaac aacttgtctt actaaagaca tagtcgttaa cttgccaata
   115681 tgtcctccag cttccatacc ctcagcaata acagcatcta ccccaagctt ttccatacgt
   115741 ttggctagcg caacgcttgg gacaacagga acaacgatta tacccgcctg gtgcagtctt
   115801 tccatatact ttcctggatt tcctgcgcct gttgttacta ctttaacacc ttcttcaatg
   115861 accagatcaa cgatatcatc agcaaaagga gataaaagca tgatattaac cccaaaaggt
   115921 ctatcagtaa tagctttaac acggtcaatg ttggctttaa caacttcttt tggagcattt
   115981 cccccaccga tgatacctag cccaccagca ttggacactg ctcctgctaa atcaccatcc
   116041 gcgacccagg ccatacctcc ttgaaaaatg ggataatcaa tattaagtaa ttctgtaata
   116101 cgtgttttca taataacttt ctataaaaaa taaggagaat aatttgataa tcaaactatt
   116161 atagtaagaa gaaagagcga gctagatcct aaaaagagtc taatcccacc ctaatggttt
   116221 gattaatact tattgttttt ttagtgatga acatgaacat aacagcagta agcttttcat
   116281 agacttctga tgttacttgt cacttttatc cttattttga cttttcctca acgtaagcaa
   116341 caaggtcacc aacagtattt aatccttctt ctgtttcaat ttgaatatca aaagcatctt
   116401 caatttctga aataacttgg aaaacatcaa gtgaatctgc atctaaatca tcaaatgtag
   116461 tttctagtgt tacttcttct gtctccttac caagttcttc aacaataatt tcttgtactt
   116521 tttcaaatac tgccatgttt atttctcctt aaaaaatata aatttgtttt tataaatgtg
   116581 ctaggcacat gaataactag attttaacaa ttagacttcc ccatgtcaaa cctccaccaa
   116641 aaccggaaag taagattttt tgggtaccat ctaacctaat ctgtcccttt tgaacagcct
   116701 ctgacaagag gattgggata ctagcagcac tagtattacc ataacgcatc atgttttcaa
   116761 ggaatttttc ccgaggaaca tcaatcttgc gtgctatttt atcaagtata cgacgattag
   116821 cttgatgcaa taaacaatag tctatatcat cttttgtaat atctgattgc gccattagtg
   116881 tgaggatgct ttttgacaca tccctaatcg caaaatcaaa tatggcacgt ccatccatct
   116941 gaatagtcgc tatggctttt ttgccaattg agtaaggaga tgaaagacta gtttctcctg
   117001 aaattaaact ctgacatctc gcaccatctg tgtgtaatgt ttccgctaaa acatgtttat
   117061 ctttactggc ttccagtagc acgccaccag ctccgtctcc aaaaagaacg gctgtcgctc
   117121 gatcctgcca gtttactaac ttagataaag tctctgcacc tattaccatt ccgttttggt
   117181 aggcacctga tgcaataagc ttatctgcca tagccaaggc aaagacaaag ccactacaag
   117241 cagcagtcat atcaaaagca aaagcacttg tagccgcaat agctgcttga actttcgcag
   117301 ctgttgatgg catagtggca tcagggctga tagttgcaac aataataaaa tcaatagcat
   117361 cagcttttaa cccagactga gtcaaaagct gatcagcaac ctgaatagct aggtcactag
   117421 tcatttcatc tctagaaata tggcgttctg ctattcctgt tcgagaaaag atccactcat
   117481 gactagtgtc cattatgcta gctaaatcat tattagtcac taactgctgt ggaacatagt
   117541 gggctacctg actgatttta gaaaaaatca tttaaaccaa atcctccaaa aattgatgta
   117601 gattccctag tccacgcacc aatgcctgca tctcttcatc actcatatca gcaatgacat
   117661 gtccaaccat atttttatgg aactttgcat ggaggcggtc caaaagtcga cccctttttg
   117721 ttaatgacag gtaaacaact cgcctatctg agcgtgatcg cgttcttgcg atataacctt
   117781 ttgcttctaa tttatttaag ctagtcgtta ctgtccctaa cgttaccatt aattctctgg
   117841 cgatatcact tggagtcacc tgatcatatt tgccgataat ttcaatagtg tgcatctctt
   117901 ttaaagagac atcactaaac tgactcgtct ttaagctcat ttcttcaata accaaaatcc
   117961 ggttgaaaat atcaactaag tattggttaa ttttgtcata ttccaagtaa acacctccta
   118021 gcaataaact ttgacaatca aattatatca aaggtcaaag tattttgcaa gcaatagctg
   118081 tcttacttcc cttgaaaatt tggtcggcgc ctttctccaa aagctatgac accttcttta
   118141 aaatcttcct tgaaagctag ctcctcttga atagcaagct ctgccttagc ataatcttcc
   118201 catcctgtga aaaagctttg ccagaccaat gatttcattc cagcataaga atttgaagag
   118261 ccacgtctca atcgctttaa aagttgaaga caaactttgt ctagtttatc agattctgcc
   118321 gtacggtaga caaacccata atcgagacct ttatcagcag taattccttc acctgtcatc
   118381 acaaggtgag ttgcacgatt aagtcctact gcacgagtca atagaaataa accaccggca
   118441 tccggtgcta gtccaacatt tacaaaagct tggataaatt ttgtttgagt actagcgata
   118501 caaaagtcaa cagctaaagc tatattaaaa gccgctccag ctacagctcc atcggcgcaa
   118561 aggatgactg gttttggcaa atgcttgatt gcaaaagaaa tttcttgtac cagttcagca
   118621 atcttgacta gcgactgcac attatctttt gcaacagctt cttgcatttc aactaggtca
   118681 ccaccaactg aaaacacttt tccaacggct ttaattaata aaaaacgcac agatgtatcg
   118741 cgtttaactt ctgctaatgc taccagaatc tcttgacaaa ttggaatatt aaaaccgttt
   118801 gaaacctctg gacggtttaa agtcaatgtc gcaagatcat ctacaacatc aaagatgatg
   118861 tgtttaaact gcataacaat cctcttttct gataatttat ttgactaaga aattatttct
   118921 ctttaaaatc atttga
//
LOCUS       DATTYN010000004        93049 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.04, whole genome shotgun sequence.
ACCESSION   DATTYN010000004 DATTYN010000000
VERSION     DATTYN010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 93049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93049
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.04"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            259..1818
                     /locus_tag="VB649_000388"
     CDS             259..1818
                     /locus_tag="VB649_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEP1669369.1"
                     /translation="MIELNDEFIRKETIELAKDGPRVHTTQYETKVPRLHKCYLLFFS
                     IIISSLTIAVPFLTDAANGLQSQNLYIGMMLTKGQLPYSDAFTTGGLFYFVIIALSYY
                     LGSTLWLVFVQVFCFYLSGLYLYKLINYMTCFQKVALTFSISYYLLSVSLGFGGLYPT
                     QLAMPFILISAWFLTKYFACLVKDEAFILFGFVGALAMLIDPSTLIFWSFACVTVFSY
                     NISQKHLARGFYQLLASIFGMILVFYTAGYFILNLQVLNPYLSQTMIYPLTFFKSGNL
                     SLLFGLAIQLFFALGLGLLTGMGNVIRRFKNNSDRVVKWLFVMVILESILVAIFSQDY
                     RPYHLLPLLPFGLILTAIPVGYQYGIGLGQSSHRRRHGKNGFGRVMMIYLKRHFYLPI
                     LIVGTILICSTYCFISSIPLNQERDHIASYLEQKLNKTQSIYVWDDTSKIYLDSKAKS
                     VSQFSSPDINTQKASHRKILEDELLENKAAYIVVNRYKNLPKIIQKVLSTNYKVDKQI
                     TTKSFIVYQKK"
     gene            1915..4113
                     /gene="nrdD"
                     /locus_tag="VB649_000389"
     CDS             1915..4113
                     /gene="nrdD"
                     /locus_tag="VB649_000389"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEP1669370.1"
                     /translation="MVSLEEDKVTVQPDIKVIKRDGRLVNFDSTKIYSALLKASMKVT
                     RMSPLVEAKLEAISDRIIAEIIERFPTNIKIYEIQNIVEHKLLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLINKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKM
                     LPSHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAKKWIVETKRESYAF
                     EKTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIDLTG
                     SFKSPMGCRSFLQGWKDENGQDVTSGRMNLGVVTLNLPRIAMESNGDMDKFWELFNER
                     MLISKDALIYRVERVTEAKPANAPILYQYGAFGKRLEKTGNVNDLFKNRRATVSLGYI
                     GLYEVASVFYGGQWEGNPDAKAFTLSIVKAMKQACEDWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTEKFGIVTDITDKEYYTNSFHYDVRKSPTPFEKLDFEKDYPEAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYNCQFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGL"
     gene            4295..4441
                     /locus_tag="VB649_000390"
     CDS             4295..4441
                     /locus_tag="VB649_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669371.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSKKKTDKKSRVQELKARFLEKSK
                     KQDN"
     gene            4470..5405
                     /locus_tag="VB649_000391"
     CDS             4470..5405
                     /locus_tag="VB649_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEP1669372.1"
                     /translation="MLNIGIVGLGAISQKAYLPYMRQLSDITWHLSTRNAAVRQQVGQ
                     LFGHAILYSDVKELSKTSLDGVFIHAATSAHAELASLFLNQGIPVFMDKPIADNYLMT
                     KNLYDLAKENKTFLMAGFNRRFTPRVKDLSILSTKRKVAAEKNDLDRPGDMTFKLFDF
                     FIHPLDTALFLTEGTLLKGHFQYHLEAGLLSQVMVTLMTESMTTTASMNLQSGSRREV
                     MEVQRAEETYHLENLDELSIYKGTKKRVLGFASWDTTLHKRGFETMIDAFLEAISTGV
                     NPVSPESSLLSHWICQQIADSQLSYGELTVELPKD"
     gene            5414..5923
                     /locus_tag="VB649_000392"
     CDS             5414..5923
                     /locus_tag="VB649_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP1669373.1"
                     /translation="MEIRRPTLKDKDAVLSMINEFLEQKSATAGLWHFNVNDFNYETW
                     LEDSLRQEMGLASQGVPAIQYVAFDEKNQALGFLNLRLRLNASLLEKGGHIGYSVRPS
                     QRGKGYAKEMLKQAVSCAISKNITTILVTCDETNVVSRAVIVANGGVLEDSRGGTERY
                     WIEEQRGDK"
     gene            5923..6537
                     /gene="nrdG"
                     /locus_tag="VB649_000393"
     CDS             5923..6537
                     /gene="nrdG"
                     /locus_tag="VB649_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEP1669374.1"
                     /translation="MAEKCWNNPKPKEWQAEELSQGRIIDYKAFNFVDGEGVRNSLYV
                     SGCLFHCKGCYNAATWSFKAGMPYTQELEEQIMTDLAQPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRRELPEKDIWSWTGYTWEEMMLETPDKLEMLSLIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVQKSLAAKEVIIWDKLNDGDQTFEQISREDLL"
     gene            complement(6711..7442)
                     /gene="yaaA"
                     /locus_tag="VB649_000394"
     CDS             complement(6711..7442)
                     /gene="yaaA"
                     /locus_tag="VB649_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEP1669375.1"
                     /translation="MLTFLIPTAKEMTIPKESHPHLLPQDSQAILKIMAAMTTEDLAK
                     SYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQV
                     YITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSS
                     EFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKS
                     LVFAGFYYHQDLSTDHEFVYIKKEA"
     gene            complement(7484..8341)
                     /locus_tag="VB649_000395"
     CDS             complement(7484..8341)
                     /locus_tag="VB649_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP1669376.1"
                     /translation="MTYPYNSTISLGTVSLNVTDLAKMTTFYTSIIGLQVLSQDTTSR
                     QLTTDGKTVILELRQTPLPANKAYGLYHTAFLVPDRHSLGLVLNHFLTRGISLEGAAD
                     HGYSEAIYLSDPEGNGIEIYHDKAVEHWDIRDNGQIIGVTEPTDTKSILEQLTDIPKR
                     FLLAQDTRIGHVHLSVKNALASSLLYQKVFDLGDKMTIPSASWIASGNYHHHLAFNHW
                     SAPYLKKHQEGAPGLAFLTIHIETPLLFSATLKKARLHGLAILQEDSSSFTTEDEEGI
                     RVNVILGQD"
     gene            8528..8865
                     /locus_tag="VB649_000396"
                     /pseudo
     CDS             8528..8865
                     /locus_tag="VB649_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018307.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(9144..9857)
                     /gene="treR"
                     /locus_tag="VB649_000397"
     CDS             complement(9144..9857)
                     /gene="treR"
                     /locus_tag="VB649_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEP1669377.1"
                     /translation="MTKYERIYKDLEIKINKDFYKEGDFLPTEIELSQQYQASRDTVR
                     KALSLLTKAGLILKKQGRGTQVIKHHQIIFPISELTSYQELVSYSNLDSKTNVIAIDK
                     LIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTWEIAEHSIY
                     QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTE
                     SRHKLEKFKFLDFARRRPK"
     gene            10068..12092
                     /gene="treP"
                     /locus_tag="VB649_000398"
     CDS             10068..12092
                     /gene="treP"
                     /locus_tag="VB649_000398"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEP1669378.1"
                     /translation="MGKFEQDAKSLLTAIGGKENIKAVTHCATRMRFVLNDNNKANVK
                     EIEKISVVKGTFTNAGQFQVIIGNDVPVFYNDFTAVSSIEGVSKEAAKSAAKSNQNAL
                     QRVMTMLAEIFTPIIPAIIVGGLILGFRNILESVPFEFLGQQVEKGKLVFDAAGDPVW
                     NTIVRVSPFWSGVNHFLWLPGEAIFHFLPVGITWSVTRKMGTTQILGIVLGICLVSPQ
                     LLNAYAVAGTPAAEIAKNWVWDFGFFTINRIGYQAQVIPALLAGLSLAYLEIFWRKRI
                     PEVVSMIFVPFLSLIPALILAHTVLGPIGWTIGKGISFVVLAGLTGPVKWLFGAIFGA
                     LYAPLVITGLHHMTNAIDTQLIADTATRTTGLWPMIALSNIAQGSAVFAYYLMNRHEE
                     REAEISLPAAISAYLGVTEPALFGVNVKYVYPFVAGMIGSGIAGLLSTTFNVQANAIG
                     VGGLPGFMAINVKYMIPFFICMAVAIVVPMFLTFFFRKSHIMTKTEDEAKLPETPVSD
                     APVATAPHKTMQGTVITLTSPLTGEVKALSEAVDPVFAQGVMGQGALLQPTEGVLVAP
                     CDAEVSVLFPTKHAICLVTTEGLELLMHIGMDTVNLDGQGFEALVKQGDQVKAGQTLI
                     QFDIAAISEAGYATETPLVVTNQDVFTVTVEGSLPRQIKVNDKLAVAVKK"
     gene            12159..13787
                     /gene="treC"
                     /locus_tag="VB649_000399"
     CDS             12159..13787
                     /gene="treC"
                     /locus_tag="VB649_000399"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEP1669379.1"
                     /translation="MTIDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGID
                     MIWLNPFYPSPQRDNGYDVSDYMAVNPDFGTMADFENLVKAAKEHQIELMLDMVLNHC
                     STDHEWFQKALAGDPYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELVDCPVNDGKPAYTDRP
                     ITHTYLHDLNQASFGQDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDY
                     ENGQKWTIMAFDFAALRDLFHAWGEGMSQGNGWNALFYNNHDQPRALNRFVDVTHFRN
                     EGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLLVSGKSAE
                     EAFAIIKAKSRDNARTPMQWDASEHAGFTTGKPWLEVGKSYRDINVETEKEGRIFPFY
                     QRLIALRKELPIIAEGDYRAAFKDSQAVYAFERHLGDQCLLVLNHFYADEVELELPPR
                     YQHGQVLISNYEKVSICEKVMLKPYQTLAILAEN"
     gene            13995..15890
                     /gene="pepO"
                     /locus_tag="VB649_000400"
     CDS             13995..15890
                     /gene="pepO"
                     /locus_tag="VB649_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEP1669380.1"
                     /translation="MTTYQDDFYQAVNGKWAETAVIPDDKPRTGGFSDLADEIEALML
                     DTTDAWLAGDHVPDDAILANFVKFHRLVADYAKRDEVGVSPILPLIEEYQSLKSFSEF
                     VANIAKYELAGLPNEFPFSVAPDFMNAQLNVLWAEAPSILLPDTTYYEEGNEKAEELR
                     GIWRQSQEKLLPQFGFSTEEIKDLLDKVIELDKQLAKYVLSREEGSEYAKLYHPYVWA
                     DFKKLAPELPLDSIFEKILGQVPDKVIVPEERFWTEFAATYYSEANWDLLKANLIVDA
                     ANAYNAYLTNDIRVESGAYSRALSGTPQAMDKQKAAFYLAQGPFSQALGLWYAGQKFS
                     PEAKADVESKVARMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDESLSLVENAQNLAKITIAHTWSKWNKPVDRSEWHMPAHLVNAYYDPQQNQIVF
                     PAAILQEPFYSLDQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLNDWWTQEDYA
                     AFKERTDKIVAQFDGLESHGAKVNGKLTVSENVADLGGVACALEATQSEEDFSARDFF
                     INFATIWRMKAREEYMQMLASIDVHAPGELRTNVTLTNFDAFHETFDIKEGDAMWRAP
                     KDRVIIW"
     gene            complement(16057..17097)
                     /locus_tag="VB649_000401"
     CDS             complement(16057..17097)
                     /locus_tag="VB649_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEP1669381.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMDKAVELLREK
                     GMAKAAKKADRVAAEGLTGVYVHGNVAAVVEVNAETDFVAKNAQFVELVNATAKVIAE
                     GKPANNDEALALVMPSGETLAEAYVNATATIGEKISFRRFALIEKTDEQHFGAYQHNG
                     GRIGVISVVEGGDDALAKQVSMHIAAMKPTVLSYTELDAQFIKDELAQLNHAIELDNE
                     SRAMVDKPALPFLKYGSKAQLSDDVITAAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAIAFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(17231..17998)
                     /gene="rpsB"
                     /locus_tag="VB649_000402"
     CDS             complement(17231..17998)
                     /gene="rpsB"
                     /locus_tag="VB649_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEP1669382.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA"
     gene            18302..21376
                     /locus_tag="VB649_000403"
     CDS             18302..21376
                     /locus_tag="VB649_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEP1669383.1"
                     /translation="MKKGIRFQLLGSPHIFLDDKEQFFAFAKANALLYYLVVNGSVSR
                     EVAASLLWENKNTQTAKKNLRNAIYQVNKVLQADVIICPNRNLLVLNKTLDIKTDINL
                     FLADPLAHLELYQGEFLQGFYLKSGEEFDLWVSKMRMQYEQVYLKACYQKIEEKLSLD
                     AIEDVEEHLKQLIERDEFEEKNYQLLMRLYQQGNCPGKVIETYYQLANVLDKELGIQP
                     SLQSQQIYQEVVAKDRNERKIKHFLRNSNHFLGRIDEIKQLENYFANCLACQEVGALL
                     LIGDTGIGKRTLARQVLANQTQTFQIVTAKCFREEAMDSLLPWRNILDGLGDLVIQNR
                     LLTTKAWKAALKRCFPVATIFQEDNNQPFIKDHTSLLVSFIVDILQHLAEIKALVILI
                     EDCHWMDEDSLTLLQRVMNQLVHYPIAFVLTKHLGTTPELGLCLNTLMSQGRLESICL
                     EPFNRQESLAYINSQLGSQPVTAEEMEHLYQASQGNPFFLSEYTQALLRHEKFVPLTS
                     AIKAKLGLKLANLSSRDDALLNYLSCCRRPIPLNTLAQLMLLPLEEVIEMVDNLGHYY
                     ILVEESVGEEVLISFRQRIIQLYSYDRLSLSKRRLLHGQIAKRLEDLLPILTPSPHLL
                     DDIAYHYQESRQVIKALEYNLNYLDATLPFQHELFPIYSKSIGSLEKSDRDDQRLMEE
                     QFDKIRQSIADLELTYDNNRDFQQLLIRFSYLEGRYDIRTGRYQEGIKHIQKVIALAT
                     ELKQPSFLLEGYRQLIHYCIQVENKPEMRYYTSLSLEAAVSANHFEAIAISLRLNGLY
                     HLIIGELNEAERLLQQSIDFFKVTPGLQANYAIQIAAALDYLGEIAQIRYQFEKAVAY
                     QKQAIALTENKPAELSVSIFYIGLGISYFYLADFEQAEQILSLAKEALVNHSYPWKET
                     QLEIYLAMIQWKKGNYQPALTLLDYRETLMSRYRNPRDKGLIFYLMAVVKYQLIRQGD
                     TLSQQEKEMVAHLLTESFEYYYEIASTNLNPYRDCHLVSELNDLRQQLSAKS"
     gene            complement(21407..22393)
                     /locus_tag="VB649_000404"
     CDS             complement(21407..22393)
                     /locus_tag="VB649_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HEP1669384.1"
                     /translation="MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFE
                     GTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPN
                     RSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHEAAYGHYLGLRQSLSPSDDLAVINMDA
                     HFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGI
                     QFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPN
                     LAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHS"
     gene            complement(22579..24120)
                     /gene="hutH"
                     /locus_tag="VB649_000405"
     CDS             complement(22579..24120)
                     /gene="hutH"
                     /locus_tag="VB649_000405"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HEP1669385.1"
                     /translation="MTRVINLDGESLTIEDVIAIARQGVACHIDDSAIEAVNASRKIV
                     DDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLIRTHASGFGDPLPEDAVRAIM
                     LIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSLGASGDLAPLAHMVLPMLG
                     LGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVLTAIGALATYDAIQLLK
                     LSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLLEGSQNTTVATQSRV
                     QDPYTLRCMPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHVISGGNFHGEPMA
                     QPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMITQYACASLAS
                     ENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVATEIMAACQALDF
                     KPENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASAVIEDPSFLEAVEQAVE
                     LSIQF"
     gene            complement(24131..25474)
                     /locus_tag="VB649_000406"
     CDS             complement(24131..25474)
                     /locus_tag="VB649_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HEP1669386.1"
                     /translation="MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKG
                     LGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWT
                     VTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
                     IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETL
                     SIVAGEMRDPEKNVPHALLGSISIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKM
                     IGPAGAWMVSIGALISITGLNMGESIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAI
                     LVSGAIAIVLLLTGSFESLAKLSVVFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGP
                     IIPILAVIVSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI"
     gene            complement(25694..26290)
                     /locus_tag="VB649_000407"
     CDS             complement(25694..26290)
                     /locus_tag="VB649_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HEP1669387.1"
                     /translation="MTKVTIKAPSDYLQTDWSGGETNQLFLYPEDGDYKKREFSYRLS
                     TATVALRQTTFTRLDGYHRILMSLDKPITLSDLSHAKETSLAPFQPYAFEGDTRIVSR
                     GTCQDINLMYDDQYQGQLLPVWSDTPFEAPKADCQLLYALSKLTYSVTNQANQELEAN
                     HLLVIEQEASLSDLKVCLNQTSPAQTPVAVWAGLWYKT"
     gene            complement(26312..27985)
                     /locus_tag="VB649_000408"
     CDS             complement(26312..27985)
                     /locus_tag="VB649_000408"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEP1669388.1"
                     /translation="MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDAR
                     QLVALKNKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPV
                     FGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSR
                     RITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKA
                     HLEKIIIGYNFQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANI
                     AHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRRSGLRPAAVVLVATIRA
                     LKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQ
                     AVYDACDKRGVDVVISDVWANGGAGGRELAEKVVTLAEQDNQFRFVYEEDDSIETKLT
                     KIVTKVYGGKGITLSPAAKRELADLERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFT
                     VTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF"
     gene            complement(28003..28629)
                     /locus_tag="VB649_000409"
     CDS             complement(28003..28629)
                     /locus_tag="VB649_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HEP1669389.1"
                     /translation="MGLVDLSLTDFAKVLGSDAPAPGGGSAAALSGANGISLTKMVCE
                     LTLGKKKYADYQDIIEDLHTKSSRLQQDLLDAIDKDTEAFNLVSDVFDMPKETDEDKA
                     ARRTAMQKALKTAAQSPFEMMTLMVEALEITATAVGKSNTNAASDLGVAALNLKAGLQ
                     GAWLNVLINLSGIKDEDFVTDYRQKGQALLDKGCHLADDIYTKILDIV"
     gene            complement(28640..29539)
                     /gene="ftcD"
                     /locus_tag="VB649_000410"
     CDS             complement(28640..29539)
                     /gene="ftcD"
                     /locus_tag="VB649_000410"
                     /EC_number="2.1.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate formimidoyltransferase"
                     /protein_id="HEP1669390.1"
                     /translation="MAKIVECIPNFSEGQNQAVIDGLVATAKSIPGVTLLDYSSDASH
                     NRSVFTLVGDDQSIQEAAFQLVKYASENIDMTKHHGEHPRMGATDVCPFVPIKDITTQ
                     ECVEISKQVAERINRELGIPIFLYEDSATRPERQNLAKVRKGQFEGMPEKLLEEDWAP
                     DYGDRKIHPTAGITAVGARMPLVAFNVNLDTDNIDIAHKIAKIIRGSGGGYKYCKAIG
                     VMLEDRHIAQVSMNMVNFEKCSLYRTFETIKFEARRYGVNVIGSEIIGLAPAKALIDV
                     AEYYLQVEDFDYHKQILENHLLG"
     gene            complement(29627..31657)
                     /locus_tag="VB649_000411"
     CDS             complement(29627..31657)
                     /locus_tag="VB649_000411"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HEP1669391.1"
                     /translation="MSFYSETDIAAAMTVKLDDVLPEKTVFKEGIRRAPDRGFRLTQA
                     QTEIALKNALRYVPTKFHEEVIPEFLEELKTRGRIYGYRWRPKDRIYGKPIDEYKGNC
                     TAAKAMQVMIDNNLSFEIALYPYELVTYGETGSVCANWMQYCLIKKYLEVMTDEQTLV
                     VESGHPVGLFKSKPEAPRVIITNGLLVGEYDNMKDWEIAEEMGVTNYGQMTAGGWMYI
                     GPQGIVHGTFNTLLNAGRLKLGVADDGDLTGKLFISSGLGGMSGAQGKAAEIAKSVAI
                     IAEVDQSRIETRHSQGWVSQIAESPEEALQLARKAIDAKESTSIAYHGNIVDLLEYVN
                     DKQIHVDLLSDQTSCHNVYDGGYCPVGISFDERTRLLAEDKDTFHQMVDDTLARHFEA
                     IKTLTENGTYFFDYGNAFMKSVYDSGITEISKNGRNDKDGFIWPSYVEDIMGPMLFDY
                     GYGPFRWVCLSGKHEDLVATDKAAMEAIDPDRRYQDRDNYNWIRDAEKNQLVVGTQAR
                     ILYQDCIGRVTIALKFNELVREGKIGPVMIGRDHHDVSGTDSPFRETSNIKDGSNVTC
                     DMAVQCYAGNAARGMSLVALHNGGGTGIGKAINGGFGLVLDGSERIDEIIKSAIAWDT
                     MGGVARRNWARNEHAIETAIEYNRLHAGTDHITIPYLADDDLVTSAVDQLFH"
     gene            31949..33214
                     /locus_tag="VB649_000412"
     CDS             31949..33214
                     /locus_tag="VB649_000412"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HEP1669392.1"
                     /translation="MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDG
                     LIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVS
                     YLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETE
                     KRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAE
                     FCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLM
                     MITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPT
                     ANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNI
                     DYPFYFFATNLIHQVYKKGQLTVDRGRIL"
     gene            complement(33272..34804)
                     /gene="ahpF"
                     /locus_tag="VB649_000413"
     CDS             complement(33272..34804)
                     /gene="ahpF"
                     /locus_tag="VB649_000413"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEP1669393.1"
                     /translation="MALSPDIKEQLAQYLTLLEADLVLQVSLGDNEQSQKVKDFVEEI
                     AAMSERISIENITLDRQPSFKVAKKGHDSGVVFAGLPLGHELTSFILALLQVSGRAPK
                     VDQDVIDRIKAIDRPLHFETYVSLTCHNCPDVVQALNIMSVLNDKISHTMVEGGMFQD
                     EVKAKGIMSVPTVFLDGEEFTSGRATIEQLLEQVAGPLPEEAFADKGLYDVLVIGGGP
                     AGNSAAIYAARKGLKTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAEVEAHTKSY
                     DVDIIKAQLATSIEKKENIEVTLANGAVLQAKTAILALGAKWRNINVPGEDEFRNKGV
                     TYCPHCDGPLFEGKDVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTNNMTIIKNVATKDIVGEDHVTGLNYTERDSGEDKHLDLEGVFVQIGLVPNTAWLK
                     DSGVNLTDRGEIIVDKHGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(34825..35385)
                     /gene="ahpC"
                     /locus_tag="VB649_000414"
     CDS             complement(34825..35385)
                     /gene="ahpC"
                     /locus_tag="VB649_000414"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEP1669394.1"
                     /translation="MSLIGKEIAEFSAQAYHDGKFITVTNEDVKGKWAVFCFYPADFS
                     FVCPTELGDLQEQYETLKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     LISQAFEVLGEDGLAQRGTFIVDPDGIIQMMEINADGIGRDASTLIDKIHAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            35792..35862
                     /locus_tag="VB649_000415"
     tRNA            35792..35862
                     /locus_tag="VB649_000415"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35824..35826,aa:Cys,seq:gca)
     gene            36369..36572
                     /locus_tag="VB649_000416"
     CDS             36369..36572
                     /locus_tag="VB649_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEP1669395.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEG
                     QKVAFDVEEGQRGPQAVNITKLA"
     gene            36768..37229
                     /locus_tag="VB649_000417"
     CDS             36768..37229
                     /locus_tag="VB649_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEP1669396.1"
                     /translation="MPTKNTSDSIEEYIKELLAKSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGNLMATIEDCISEQVFTDSI
                     QLLFDEHLLTEREGNIILAVASDDVLGTDGSTIRARMLYRLLQRIDRKGSN"
     gene            37229..39673
                     /locus_tag="VB649_000418"
     CDS             37229..39673
                     /locus_tag="VB649_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP1669397.1"
                     /translation="MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLA
                     NMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVDFRPQSKTLTNLLAFAQAISQIT
                     RDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDSGNGQPRLADLRKAIERHAGYSK
                     EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQ
                     EVSRMIQVLSRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMM
                     SVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGSGIDSTLDAANILKP
                     ALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYET
                     YHNVSISNEAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPID
                     QALINGDMKKVSRLLAKEAKGQMRKPTPVTEDDILATLSKLSGIPLEKLTQADSKKYL
                     NLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTELAKAL
                     AEVLFDDDAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGILTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFG
                     VKGIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFHSLTQDNMRDVVKIMVQPLIT
                     TLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGH
                     TLKIGLSHGKLTFHIA"
     gene            39851..40141
                     /gene="groES"
                     /locus_tag="VB649_000419"
     CDS             39851..40141
                     /gene="groES"
                     /locus_tag="VB649_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEP1669398.1"
                     /translation="MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSE
                     TGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIVAIVTK"
     gene            40177..41808
                     /gene="groL"
                     /locus_tag="VB649_000420"
     CDS             40177..41808
                     /gene="groL"
                     /locus_tag="VB649_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEP1669399.1"
                     /translation="MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEG
                     LKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGS
                     GSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQ
                     IALNAGYEGSVVIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF"
     gene            42059..42382
                     /locus_tag="VB649_000421"
     CDS             42059..42382
                     /locus_tag="VB649_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1669400.1"
                     /translation="MNHFGEIFKTFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTI
                     STFMLILDESNMPIDEFMYAVHDFHRDNTIQDSDGLKQLLHAQLASTDKKEMFTDIFW
                     HIQHV"
     gene            complement(42993..44492)
                     /locus_tag="VB649_000422"
     CDS             complement(42993..44492)
                     /locus_tag="VB649_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEP1669401.1"
                     /translation="MINKKISLGVLSILTAFSLQSVSYACTGFIIGKDLTKDGSLLYG
                     RTEDLEPHHNKNFIVRLAKDNPAGEKWKDLSNGFEYPLPEHSYRYSAIPDVTPNKGVY
                     DEAGFNEFGVSMSATVSASANDAIQKIDPYVKNGLAESSMASVILPSVKTAREGVALI
                     AKIVTEKGAAEGNIVTLADKDGIWYMEILSGHQYVAIKFPDDKYAVFPNTFYLGHVDF
                     NDKENTIASEDVEKVAKKAKSYTEVDGKFHIAKSYNPPLNDANRSRSFSGIKSLDPDS
                     KVTYKDSNYELLQSTDKTFSLEDAMKLQRNRFEGLDLKPLDQMALDGKGKPKSKKAVK
                     GYAYPISNPNVMEAHIFQLKKDIPAELGGGVMWLSIGSPRNAPYLPYLGNISRTYEAY
                     QEKSTQYNDKSWYWTVSHINDLVAAHPKSFGTKVIDEMKGLEKTWIAEQDQTNKELNQ
                     LVQTDPTAAQEKADAVSMARAEKTFKRLKAIEAKLVKEKPKNKKGLNRS"
     gene            44739..46379
                     /locus_tag="VB649_000423"
     CDS             44739..46379
                     /locus_tag="VB649_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669402.1"
                     /translation="MTKPFHHKKLKQITIIAATSLFLFLIGGAFYYSKNHCINAYLKA
                     RSAQSGPVFENIKAYLVWDDTNEQITNDEAMYTKFRRYSQKELRQKKQDLKAASQDSA
                     VQVKSVGRRFWIFPDYRIAIKPMDLTIKTNVPQADVLLNQKKVAVSDSEQFSVKLDRL
                     PTAEYTASIRGKHNGRNIKVNKSYDGDNPVLDLSVSFRTFLVTSNAKQGDLYFDDNHI
                     GTLKDGQLQVEDYPVTENAQAYMKTTFPDGELRSQKYALADVEEGATLEILVTDLLEE
                     DKAGELLVSAFDQLMHYLSTGQDSSNLRSVFEAGSSNAFYRGLKESIKAKFQTDTRKA
                     SRLNIPSILLTTMTQVGKTTYVLDFTATYEFLYDNSTDPEQHTSGHINQDLTGKVTVK
                     KVGQHYLISQSGSKNITVVKEDNQLKAPSVFPESILGTWTGQANGLSIHMSLASDGTI
                     TTKVEDQKGNRSKETRTAKISKVEDKGNGFYLYTPDPGSDISALVPEGGLGGANVKYA
                     YGFKISGKTASPVVWQAALTHEFDYTKPLSGVTLQKQP"
     gene            complement(46468..47469)
                     /locus_tag="VB649_000424"
     CDS             complement(46468..47469)
                     /locus_tag="VB649_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP1669403.1"
                     /translation="MTSVKVLKLSLLLLPPKWLSTLLKNTITGSMKTTNKPSKGFTVT
                     LKNPFEELTVKALLEEQLLIPRKIRHFLRTKKHVLINGHPVNWQSCVKYGDQVKLFFD
                     HEDYPEKIIVMGQAEKVTCLYEDEHIIIVNKPEGMKTHGNDPTELALLNHVSAYTGQT
                     CYVVHRLDKETSGAILFAKTPFILPILNRLLEKRDIHREYLALVHGSLDSPRVTYHHP
                     IGRHRHDRRKRVVDPINGKKAITEVTLVKNFHKTASLLNCQLQTGRTHQIRVHLAHQG
                     HVLFGDPLYSNGKKDCARLMLHAYQLRLKHPLTQEDICVQAKSATFDAVLNAQKARK"
     gene            48045..48425
                     /locus_tag="VB649_000425"
     CDS             48045..48425
                     /locus_tag="VB649_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEP1669404.1"
                     /translation="MKTIRRYDVNEDRGHTGLVEAGDFYYLNYCVGNVGQDIESQING
                     AFDEMERRLALVGLTLDAVVQMDCLFRDVWNIPVMEKMIKERFNGRYPARKSIQTEFA
                     HHGGPQGLLFQVDGVAYSKHISMT"
     gene            48464..50800
                     /locus_tag="VB649_000426"
     CDS             48464..50800
                     /locus_tag="VB649_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP1669405.1"
                     /translation="MRFLELLQKKFFPKAYQEKQFLMHQKARLTPQHNQKQYSPNAHH
                     LDSSATKNSEQDPAIALQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIG
                     KLLMILIGTLVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSY
                     VELNAISDDLENAVIATEDRTFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAY
                     LSQDQTIKRKAREFFLALELTKKYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTA
                     ANLTLDEAATLAGMLKGPEIYNPYHSLKNATHRRDTVLGAMVDAKKITQTKAQQARAV
                     GLKNRLADTYVGKTDDYKYPSYFDAVISEAIATYGLSEKDIVNNGYKVYTELDQNYQT
                     GMQTTFNNDELFPVSAYDGSSAQAASVALDPKTGGVRGLIGRVNSSENPTFRSFNYAT
                     QAKRSPASTIKPLVVYAPAVASGWSIEKELPNTVQDFDGYQPHNYGNYESEDVPMYQA
                     LANSYNIPAVSTLNDIGIDKAFTYGKTFGLDMSSAKKELGVALGGSVTTNPLEMAQAY
                     AAFANNGVIHPAHLINRIENARGEVLKTFTDKAKRVVSQSVADKMTAMMLGTFSNGTA
                     VNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTPDVVISQWVGFNQTDENHYLTDS
                     SAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISAVYGVNETGNQSGVDTQSIID
                     GLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR"
     gene            50849..51001
                     /gene="rpmG"
                     /locus_tag="VB649_000427"
     CDS             50849..51001
                     /gene="rpmG"
                     /locus_tag="VB649_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP1669406.1"
                     /translation="MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYT
                     LHKETR"
     gene            51015..51191
                     /gene="secE"
                     /locus_tag="VB649_000428"
     CDS             51015..51191
                     /gene="secE"
                     /locus_tag="VB649_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEP1669407.1"
                     /translation="MGFISGTFKVLKDTTWPNRKQRWKDFISVLEYTAFFTVIIYIFD
                     QLLAKSVLALINLF"
     gene            complement(51428..52201)
                     /locus_tag="VB649_000429"
     CDS             complement(51428..52201)
                     /locus_tag="VB649_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEP1669408.1"
                     /translation="MTDRGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQQ
                     KAPEQMLTSDGLNTKIVGEEKTVDEVIEEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAAGLHTAIETTAFAKHEQFVTLIDYVDFIYTDLKHYNQLRHQKVTGVRND
                     LIIKNIHYAFQAGKEIVLRIPVIPQFNDSLDDAKAFSELFNQLEIDQVQLLPFHQFGE
                     NKYKLLGREYEMAEVKAYHPEDLTDYQAVFLNHNIHCYF"
     gene            52327..53073
                     /locus_tag="VB649_000430"
     CDS             52327..53073
                     /locus_tag="VB649_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019317626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP1669409.1"
                     /translation="MNRLERIIQLVSQKKKIDVNSLSEQLDVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQNKRNIKIITNSCFIANYIRQYSSCQIILLGGYYQPNSEVTVGPLLKEMISLFHV
                     NRVFVGTDGFNKDLGFMGKDMMRSEGVRYMADAAEEVVILTDSSKFSKTSLVHQLSLA
                     DVNRVITDQALDKQTQELLSASGLVLDFVS"
     gene            53089..54069
                     /locus_tag="VB649_000431"
     CDS             53089..54069
                     /locus_tag="VB649_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEP1669410.1"
                     /translation="MKEERRRLLAKVAYLHYVQGKSQTLISKEMNIYRTTVCRMLAKA
                     KEEGIVRIEIADYDADLFALEEYVRQQYGLEKLDLVPNQVEDTPMDTLTNVAKTAAEV
                     FRHVVKDGDKIGLSWGATLSCLMDELNPKAMKDVFIYPLAGGPSHINAKYHVNTLVYR
                     LARIFHGNSAFMNAMVIQEDKHLAKGILQSKYFNDILTSWDQLDLALVGIGGEPNSLE
                     QSQWRDLLTSSDHDQLKYEKAVGEVCCRFFDQAGQPVYTGLQDRTIGISLEQLRRVPK
                     TMAVATGKHKAKAILAALKAGFINYLVTDKETMLAVLALDEDIDLNNVLL"
     gene            54357..54677
                     /locus_tag="VB649_000432"
     CDS             54357..54677
                     /locus_tag="VB649_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP1669411.1"
                     /translation="MQVIVPDQIIMGLILNAGDAKQHIYQALKCAKEDDYATSEKEMA
                     LADDALLEAHNLQTQFLAQEASGNKSEITALFVHSQDHLMTTITEINLIKEIIDLRKE
                     LATK"
     gene            54705..55013
                     /locus_tag="VB649_000433"
     CDS             54705..55013
                     /locus_tag="VB649_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP1669412.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIDCQIEAYAQGKLAD
                     YAPLLDVALLGPQVAYTLDQSEAICKDNDIPIAVIPMADYGMLDGNKVLDLALSLVKE
                     "
     gene            55023..56327
                     /locus_tag="VB649_000434"
     CDS             55023..56327
                     /locus_tag="VB649_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP1669413.1"
                     /translation="MAKMNMQNIIMPIMTFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVFGADWTEPFMQVYHGTFAIMGLISCFAIGYSYAKNSGVEPLP
                     SGVLSLSAFFILLRSSYVPAEGEAIGDAISKVWFGGQGIIGAIVIGLTVGAVYTTFIR
                     RHIVIKMPDQVPQAIAKQFEAMIPAFVIFTLSMLMYIIAKSVTGGGTFIEMIYDVIQV
                     PLQGLTGSLYGALGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALMAAGELS
                     LDKGAHIVTQQFLDSFLILSGSGITFGLVVAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVLAALTVYGAIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGAIVQILILIMSTLVYFPFFKIQDNMAYQNEQATEES"
     gene            56538..58955
                     /locus_tag="VB649_000435"
     CDS             56538..58955
                     /locus_tag="VB649_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEP1669414.1"
                     /translation="MTETKSPYFGHLTDRMTHYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRDIAPFWENNNLRARCGVLLPEEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFYDSVFIVIDAV
                     KTYAKRYAKLARELAKTAKPERQAELLDIARICDKVPYEPAKTFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNT
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTPEELWQALESDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            58968..59636
                     /locus_tag="VB649_000436"
     CDS             58968..59636
                     /locus_tag="VB649_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEP1669415.1"
                     /translation="MEYMLDTLDLEAIKKWHHILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVIAQDYEGILKDAAEIRRQCGDSVYVKVPVTTEGLAAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIEQLAEAINRENA
                     DSKILAASFKNVAQVNKSFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWEAIHH
                     RKSI"
     gene            59693..60781
                     /locus_tag="VB649_000437"
     CDS             59693..60781
                     /locus_tag="VB649_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEP1669416.1"
                     /translation="MKVFASPSRYIQGKNALFTNAKTLKQLGDSPILLCDDVVYGIVG
                     ERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAI
                     ADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMA
                     SCDRQVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVA
                     YGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGE
                     TIHQMPFVITPEDVAAALVAVDAYVTSR"
     gene            complement(60863..61372)
                     /locus_tag="VB649_000438"
     CDS             complement(60863..61372)
                     /locus_tag="VB649_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HEP1669417.1"
                     /translation="MSTDHQLREVSYQLLAERGVSLEAIAELVLFLQNDYIPNLTMAE
                     CLESVEAVLAKREVQNTIITGVELDKLAEANQLSEPLLSILKTDQGLYGIDEILALSI
                     VNLYGSIGFTNYGYLDKTKPGIVDKLNHKDGKSCHTFLDDIVSAIAAAAASRIAHNDP
                     AKSAITNQQ"
     gene            61736..62551
                     /gene="sdaB"
                     /locus_tag="VB649_000439"
     CDS             61736..62551
                     /gene="sdaB"
                     /locus_tag="VB649_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase B"
                     /protein_id="HEP1669418.1"
                     /translation="MNLLGSRRVFSKKCRLVKFSMVALVSATMAVTTVTLENTALARQ
                     TQVSNDVVLNDGASKYLNEALAWTFNDSPNYYKTLGTSQITPALFPKAGDILYSKLDE
                     LGRTRTARGTLTYANVEGSYGVRQSFGKNQNPAGWTGNPNHVKYKIEWLNGLSYVGDF
                     WNRSHLIADSLGGDALRVNAVTGTRTQNVGGRDQKGGMRYTEQRAQEWLEANRDGYLY
                     YEAAPIYNADELIPRAVVVSMQSSDNTINEKVLVYNTANGYTINYHNGTPTQK"
     gene            complement(62793..63635)
                     /locus_tag="VB649_000440"
     CDS             complement(62793..63635)
                     /locus_tag="VB649_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP1669419.1"
                     /translation="MEIGETVEFIRHSKNISIKQVCGDYLTRQTYYRFIKNNLDISSK
                     KLLYILDNLNVNVDEFLFISNNFKQYKEFIDMDTAKHYFECRNIEGLNHILDSYKDSK
                     STKEKNLFALVKVLLATLTEEDCLTERTYLSNYLINIETWSHYETVLFNNCMFIFESC
                     FIEMVFSKVILNLDKYNTLRYYGNESIRMFVNMLILFIQRQEYDKASEILAKIEDYQL
                     NDDCLYERCCVSFFDGIIGLINGKEGAEQKCVQILEIFQLLNCKTIHHMFQTYLEAIK
                     HKLS"
     gene            64134..64304
                     /locus_tag="VB649_000441"
     CDS             64134..64304
                     /locus_tag="VB649_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669420.1"
                     /translation="MDNPKKDKGLSLGVVDPITILITESVINKMRTVPYHLKKLSSTT
                     YCLLADLAYQSA"
     gene            64576..65772
                     /gene="speB"
                     /locus_tag="VB649_000442"
     CDS             64576..65772
                     /gene="speB"
                     /locus_tag="VB649_000442"
                     /EC_number="3.4.22.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine proteinase exotoxin SpeB"
                     /protein_id="HEP1669421.1"
                     /translation="MNKKKLGIRLLSLLALGGFVLANPVFADQNFARNEKEAKDSAIT
                     FIQKSAAIKAGARSAEDIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILG
                     YSTSGSFDVNGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHY
                     NQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTL
                     SSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDY
                     GPSSGSAGSSRVQRALKENFGYNQSVHQINRSDFSKQDWESQIDKELSQNQPVYYQGV
                     GKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPSALGTGGGAGGFNGYQSA
                     VVGIKP"
     gene            65774..66079
                     /locus_tag="VB649_000443"
     CDS             65774..66079
                     /locus_tag="VB649_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spi family protease inhibitor"
                     /protein_id="HEP1669422.1"
                     /translation="MEMHFVRTEPEARRIAETFCAENTQTKTPMRVQQLSYPSDTDHS
                     SGELYIYALSPAGFIIVSGDTRAHTILGYSFDNNLDLNHDNVRSMIEAYQKQISSLD"
     gene            66557..67486
                     /gene="prsA"
                     /locus_tag="VB649_000444"
     CDS             66557..67486
                     /gene="prsA"
                     /locus_tag="VB649_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEP1669423.1"
                     /translation="MKQMNKLITGVVTMATVVTLSACQSSHNNTKLVSMKGDTITVSD
                     FYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQ
                     SGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEE
                     DAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNR
                     SEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIA
                     KALDKANVKIKDKAFANILAQFAKPNQKQPAQK"
     gene            complement(67757..67993)
                     /locus_tag="VB649_000445"
     CDS             complement(67757..67993)
                     /locus_tag="VB649_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669424.1"
                     /translation="MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPTAHGPCD
                     ETHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG"
     gene            68417..71524
                     /locus_tag="VB649_000446"
     CDS             68417..71524
                     /locus_tag="VB649_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEP1669425.1"
                     /translation="MTNCKYKLRKLSVGLVSVGTMLIAPTVLGQEVTANTETSTTPAT
                     TTPSAGTGTATTSGTATTTPSATTDAGGEAGSGTNGASSVTSSGGSQSSGTTPASPQP
                     QAQTTPAATSISSNSSSDGQIPKTAITSPSTPVAASNNSNQEASAETEPQTMEVEKYT
                     VDKENSKLNIKDGDKPKNGSSVDDKDTKLIRNRDGKQRDIVDVTRTVKTNEDGTIDVT
                     VTVKPKQIDEGADVMALLDVSKKMTEEDFNNAKEKIKKLVTTLTGTGKNGGEHKARNS
                     VRLMTFYREISKPIDISGKTEEQLDTLLNKLRQEAKDEYDWGVDLQGAIHKARDIFNK
                     EKEKESKKRQHIVLFSQGESTFSYDIKNKDDKKLQKTHLTTVTTSNPLFSWFPIFDHT
                     NRKADMIDDIKYLIKWGEALGIEGLSGLKDKLSLAGLASSALGGLFSGGSLTEYLSLK
                     EYQSDSLKADQFNYEKRVGEGYYYHSFSKRETADMPNRDLIKQNLEGLFKEKDGNWFK
                     SILDKLSLTDKYQKAKEAALLKVLDYLFYKREYHYYNHNLSAIAEAKMAQQEGITFYS
                     VDVTDLNTARRVKRQTATYTDDKKKEIEKIEEERNKKFDAYLRKMSEDNDFLSDVEDK
                     DKFKDTLTDVTVTETFEDGVNVKENLYQTSLDSNSNGSNSNSGGDVRHTKPSGSSWWT
                     FSGTKESLTWTISKDQLKEAFEKNGFLTFKYKLQVNKDKLLKDIKRTKRGTSTENKTS
                     VTKDIISNTITYKINEQKVKGNKLENVKLTYTKETVPVPDVEGEVVPIPEKPLVEPMT
                     PLYPAIPNYPTPQLPKDEDLEISGGHGPIVDIVEDTGTGVEGGAQNGVVSTQENKDPI
                     VDITEDTQPGMSGSNDATVVEEATTPQRPDILVGGQSDPIDITEDTQPSVSGSNDATV
                     VEEATAPQRPDILVGGQSDPIDITEDTQPGMSGANDATVIEEDTKSKRFFHFDNEPQA
                     PEKPKEQPSLQDSNSLPQAPAYKAAHHLPASGDKREVYFTIAALTIIGAAGLLSKKRR
                     DTEEN"
     gene            71704..73641
                     /locus_tag="VB649_000447"
     CDS             71704..73641
                     /locus_tag="VB649_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEP1669426.1"
                     /translation="MTKKFIKSAVILGLASITISMTQPVEAISNSLEYQAQYKRVKEE
                     LDALKENSSKLGERSLYFRLVNRFLGWFGQVWDPLAIKETDYLLDLIGQVNYLVSNTE
                     FQAPEYKDAKNKLDLAVAGYELYLAREKERGDAPDYQVTQLTFKQLETIKTKIREALE
                     TFAQEVKTIQQKNPDLFPHAYVLNTKSKDITDKAQPFLVNGYYDVFYKQFLFTNTKDG
                     YNYNKEADNLTSYQDLIKELLDLKAEIDQLTKGKTGDDRLEMLMWQSKLTLSDSRRTS
                     RLSAYYAQGDYINKVVLSEEAPNLRTAKEKVKTLKGILYDYYVETNEPEKAKQYRVED
                     ETLPSQPEAPAKPAAPAKPAAPSPGQKPTEDEGSSQATEPANPSKEDSSTDASQGSHD
                     SENPATDNPSQPQVPDQDNHQSQVPNEKPQTDKTDTPNVPAPPQDTPKVPEAGGQSGP
                     AGNAEEKAPDSGPKESDQSSSKESPSVGEDTTPNQPDVLVGGQSEPIDITEDTITDAP
                     PTVSGHNASTQPQSVVEDTAPQRPDVLVGGQSDPIDITQDTQPGMSGSNDATVINEDT
                     KPKRVFHFDNKEPQASEKAAEQKLAPHDNHTTPQTSDDTAAPHLPASGDKPEKVFALA
                     ALTMVAAAGLLSKKRRNTDKN"
     gene            73783..74079
                     /locus_tag="VB649_000448"
     CDS             73783..74079
                     /locus_tag="VB649_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HEP1669427.1"
                     /translation="MTKQDQLIVEKMEQTYEAFNPKLANLIEALDAFKEHYEEYATLR
                     NFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM"
     gene            74226..74510
                     /locus_tag="VB649_000449"
     CDS             74226..74510
                     /locus_tag="VB649_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEP1669428.1"
                     /translation="MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKD
                     DAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN"
     gene            74934..76202
                     /locus_tag="VB649_000450"
     CDS             74934..76202
                     /locus_tag="VB649_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEP1669429.1"
                     /translation="MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEIVSSVN
                     KVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKDVFVKKGDVVKVGQP
                     LFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAP
                     DESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATTEKGKLEYDTVKSD
                     TAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIGQKVEVID
                     RKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLI
                     GSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVE
                     VTSGLTMQDKIAQPLPGMKDGMEVGSIVKP"
     gene            76189..76863
                     /locus_tag="VB649_000451"
     CDS             76189..76863
                     /locus_tag="VB649_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669430.1"
                     /translation="MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGK
                     STLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQ
                     NVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNP
                     SFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNI
                     EHSDIE"
     gene            76876..78093
                     /locus_tag="VB649_000452"
     CDS             76876..78093
                     /locus_tag="VB649_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669431.1"
                     /translation="MEDIIAALSSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTE
                     NTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVK
                     NALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYL
                     EKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNI
                     NGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLN
                     KSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEA
                     VILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIK
                     ASKLDPIEALRFE"
     gene            78187..78840
                     /locus_tag="VB649_000453"
     CDS             78187..78840
                     /locus_tag="VB649_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1669432.1"
                     /translation="MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTT
                     SYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKP
                     FSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLA
                     KRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE"
     gene            78837..80225
                     /locus_tag="VB649_000454"
     CDS             78837..80225
                     /locus_tag="VB649_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEP1669433.1"
                     /translation="MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKR
                     EFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDS
                     QNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLI
                     FSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRL
                     YASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFA
                     DRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSE
                     LKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKSGGQVMIQLKDNQLVIKNEA
                     ETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYSFVVLDQRWM
                     VFTIDFPSHHDD"
     gene            80327..81931
                     /locus_tag="VB649_000455"
     CDS             80327..81931
                     /locus_tag="VB649_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP1669434.1"
                     /translation="MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTAD
                     TDTDDESETPKKDKKSKETASQHDTQKDHKSSHTHPTPPSNDTKQTDQASSEATDKPN
                     KDKNNTNQPDSSDQSTPSPKDQSSQKESQNKDGRSTPSPDQPKDQTPDKTPEKSPEKA
                     TEKTPEPNRDAPKPIQPPLAAAAPVFAPWRESDKDLSKLKPSSRSSAAYVRHWTGDSA
                     YTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMA
                     ESSLGTQGVAKEKGANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQ
                     DLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKI
                     TSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGD
                     WQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLG
                     TISYRTFTAEQASLLTYVVGDKLPRP"
     gene            82009..82260
                     /locus_tag="VB649_000456"
     CDS             82009..82260
                     /locus_tag="VB649_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669435.1"
                     /translation="MIKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQP
                     SMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD"
     gene            82936..84537
                     /locus_tag="VB649_000457"
     CDS             82936..84537
                     /locus_tag="VB649_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP1669436.1"
                     /translation="MHVSKLFTSQQWRELKLISYLTENSNAIGVKDKELSKALNISML
                     TLQSCLTNMQFMKEVGGITYKDGYINIWYHQCCGLQEVYQKALRESPSLKLLELLFFR
                     DFSSLEELAEELFVSLSTLKRLIKKTNTYLSHTFAISIVTSPVQVSGDERQIRLFYLK
                     YFSEAYKISEWPFGDILNLKNCERLLSLLIKEVDVKVHFTLFQHLKILSGVNLIRYYK
                     GYSCSYNNKKTSHRFSQLIQHSSEIQDLSRLFYLKFGLHLDEYTIAEMFSNHLNDKLE
                     IGCAFEIINQDPTSGGRQVTNWIHLLDEMEIKLNLSITNKYEVAVTLHNASVLNEEDI
                     TANYLLFDYKKSYLNFYQKEHPRIYEAFVTSVEKLMQADNAQVSKELINQLTYCFFIT
                     WENSFLKVNQKDEKVRLLVIERSYNSVGNFLKKYIGEFFSITNFDELDCLTIDLVEIE
                     KQYDVIVTDVMVGKSEELEIFFFYKMIPEAIIDRLNEFLNVSFTDNNVMVKNLEAPSP
                     SKSHSDKEVQKPEKPDNSVKQATSS"
     gene            84727..85881
                     /locus_tag="VB649_000458"
     CDS             84727..85881
                     /locus_tag="VB649_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407887.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEP1669437.1"
                     /translation="MSKRNPNKHYSLRKLKTGTASVAVALTVLGTGLANTTDVKAETE
                     HLDVVLSAKEANKVFEERKALEKQARDLGDTINHMSQTISEQSRKIAALKSEAELKNQ
                     QALEALNNKNEQIAKLTNENAQLKEAIEDYVQTIQNASREMAAKQQELAAAKSQLEAK
                     NAEIEALKQQDASKTEEIAKLQSEAATLENLLGSAKHELTELQAKLDTATAEKAKLES
                     QVTTLENLLGSAKRELTELQAKLDAANAEKEKLQSQAAALEKQLEATKKELADLQAKL
                     AATNQEKEKLEAEAKALKEQLAKQAEELAKLKADKASGAQKPDTKPGNKEVPTRPSQT
                     RTNTNKAPVAQTKRQLPSTGEETTNPFFTAAALTVIASAGVLALKRKEEN"
     gene            86106..87287
                     /locus_tag="VB649_000459"
     CDS             86106..87287
                     /locus_tag="VB649_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407885.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEP1669438.1"
                     /translation="MARKDTNKQYSLRKLKTGTASVAVAVAVLGAGFANQTTVKAAEI
                     KKPQADSAWNWPEEYNALLKENEELKVEREKYLSYADDKEKDPQYRALMGENQDLRKR
                     EGQYQDKIEELEKERKEKQERQERQEKLERQHQDKHYQEQQKKHQQEQQQLEAEKQKL
                     AKEKQISDASRQGLSRDLEASRAAKKELEAKHQKLETEHQKLKEEKQISDASRQGLSR
                     DLEASREAKKKVEADLAALTAEHQKLKEEKQISDASRQGLSRDLEASREAKKKVEADL
                     AEANSKLQALEKLNKELEEGKKLSEKEKAELQARLEAEAKALKEQLAKQAEELAKLKG
                     NQTPNAKVAPQANRSRSAMKQQKRTLPSTGEAANPFFTAAAATVMVSAGMLALKRKEE
                     N"
     gene            87498..88562
                     /gene="enn"
                     /locus_tag="VB649_000460"
     CDS             87498..88562
                     /gene="enn"
                     /locus_tag="VB649_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M-related protein Enn"
                     /protein_id="HEP1669439.1"
                     /translation="MARQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVRAEGV
                     KATKNLSEEAKYDTLKDENTGLRGDQTKLVKKLEEEQEKSKNLEKEKQKLENQALNFQ
                     DVIETQEKEKEDLKTTLAKTTKENEISEASRKGLSRDLEASRAAKKELEAKHQKLEAE
                     NKKLTEANQVSEASRKGLSNDLEASRAAKKELEAKHQKLAEEHQVSETSRKGLSRDLE
                     ASREANKKVTSELTQAKAQLSALEESKKLSEKEKAELQAKLDAQGKALKEQLAKQTEE
                     LAKLRAEKAAGSKTPATKPANKERSGRAAQTATRPSQNKGMRSQLPSTGEAANPFFTA
                     AAATVMVSAGMLALKRKEEN"
     gene            88897..92445
                     /gene="scpA/B"
                     /locus_tag="VB649_000461"
     CDS             88897..92445
                     /gene="scpA/B"
                     /locus_tag="VB649_000461"
                     /EC_number="3.4.21.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C5a peptidase ScpA/B"
                     /protein_id="HEP1669440.1"
                     /translation="MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQA
                     VETPQPTAVSEEAPSSSKETKIPQTLGDAEETVADDANDLAPQAPAKTADTPATSKAT
                     IRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKA
                     KKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEG
                     AMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDET
                     KKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSP
                     DKQLTETATVKTDDHQAKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALI
                     ERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDN
                     SKKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAK
                     LSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATTLYDEDEKAYF
                     SPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELY
                     YQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMK
                     NGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSD
                     AKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGT
                     FAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGN
                     VVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPIS
                     SGAKEQHTDFDVIVDNTTPEVATSATFSTEDCRLTLASKPKTSQPIYRERIAYTYMDE
                     DLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLE
                     GHSNKPEQDGSDQAPDKKPETKPEQDGSDQGPDKKPETKPEQDGSDQAPDKKPEAKPE
                     QDGSGQTPDKKPETKPEQDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKATTRDQLP
                     TTNDKDTNRLHLLKLVMTTFFLGLVAHIFKTKRTED"
     gene            92542..>93049
                     /locus_tag="VB649_000462"
     CDS             92542..>93049
                     /locus_tag="VB649_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEP1669441.1"
                     /translation="MLRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDGIPPI
                     SLTQRTTATTSEKWHHINDDGSIPLGISLEDAKEDFKKEVKESLLSEEQKETYKRKID
                     AETDKDKLLLTYHSEYMTAVKTLPTSTEPVETPVQGTQASDSMVTDDSTSVTTDSPEK
                     TPSTETPAP"
BASE COUNT        29621 a        18014 c        19500 g        25914 t
ORIGIN      
        1 ttacagtatg tgaaaatata tcagaaattg actaaataaa agattctgtt atacttgttt
       61 tataatattc tttgacgata atatcatttt tcaacttact ttgtttatgc actgtcactt
      121 tgctatgtgc aatacaaagt catgttattt atctcatact aaaaaaataa tggataatag
      181 ctatgttaga ctagtgatat gaagaaatat tgcttttatt gaatcgttag agaatatgat
      241 atttcaagga gaaaaatagt gatcgagtta aacgatgaat tcatccgaaa agagacgata
      301 gaactggcca aagatggccc acgagtacac accactcaat atgaaactaa agtacctcgg
      361 cttcataaat gctatctgct tttctttagc attattatca gttctttaac aattgcagta
      421 ccttttttaa cagatgcagc caatggtctt cagtctcaaa acttatatat aggaatgatg
      481 ttaacgaagg ggcaacttcc ctatagtgat gcttttacaa caggagggct cttttacttt
      541 gttatcattg cattaagtta ttatttggga tcgacacttt ggctagtctt tgttcaggtg
      601 ttttgttttt acttatctgg tttatatctt tataaactca ttaattatat gacatgcttt
      661 caaaaagtgg ctttgacttt ttcaattagc tactatttgt tgtctgttag tcttggtttt
      721 ggaggattgt atcctactca actggctatg ccatttatat taatatcggc ttggttttta
      781 actaagtatt ttgcctgttt agtgaaagat gaggcattta ttctttttgg ctttgtaggt
      841 gctcttgcaa tgctaattga cccgagtacc cttatctttt ggtcttttgc ttgtgtgaca
      901 gttttttctt ataatataag ccaaaagcat cttgcaagag gtttttatca actgctagct
      961 tcgatttttg gaatgatttt agttttttac acagcaggat atttcatttt gaacttacaa
     1021 gtgctaaatc cttatttatc acaaacgatg atttatcctt tgactttttt taaatcagga
     1081 aacttatcgt tgctttttgg actggctatt cagttgttct tcgctttggg gcttggtctt
     1141 ttgacaggaa tggggaatgt cattaggcga tttaaaaaca attctgatag ggtcgtcaag
     1201 tggctatttg tcatggtcat tctagaatct atacttgtgg ctatattttc acaagactat
     1261 cgcccctatc atcttttacc tcttttacct tttggattaa ttttgactgc tattcctgtt
     1321 ggctatcagt atggtatagg attaggtcag agtagtcatc gcagacgtca tggtaaaaat
     1381 ggttttggtc gagtaatgat gatttatctt aagagacact tttatttgcc aattttaatt
     1441 gtagggacaa tactaatctg ttctacttat tgtttcatta gtagtattcc tcttaatcag
     1501 gagcgtgatc atattgctag ttatttagaa cagaaactaa ataaaactca atctatttat
     1561 gtttgggatg atacttctaa aatttatttg gacagtaaag ctaaatctgt ttctcaattt
     1621 agttctcctg acatcaatac gcaaaaagcg agtcatcgaa aaatattaga agatgaacta
     1681 ttagaaaata aggctgctta tatcgttgtt aatcgctata aaaacctgcc taaaatcatt
     1741 caaaaagtat tatctactaa ttacaaagta gataaacaga taacgacaaa aagttttatt
     1801 gtttatcaga aaaagtaatc taatatcaat atattgtgtg cgagcaaaaa acttgacaca
     1861 atatattgat ttttttagtt gtcgtgatat aatagttccg taaggagatt tgatatggta
     1921 agtttagaag aagacaaggt gactgttcaa cctgatatta aagtgattaa acgagatggt
     1981 cgccttgtta attttgatag tacaaaaatc tatagtgctt tattaaaagc aagcatgaaa
     2041 gtaactcgga tgtcgccact tgttgaggct aaattagagg ctatttctga tcgcattata
     2101 gcagaaatta ttgagcgttt tccaactaat atcaaaattt atgaaatcca aaatattgta
     2161 gagcataagc ttcttgcagc taatgaatat gctattgcaa aagaatacat taattatcgt
     2221 actcagcgtg actttgcacg ttcacaagca acagatatca atttttctat tgataaatta
     2281 attaataaag atcaaacagt tgttaatgaa aatgctaaca aagatagcga tgtttttaat
     2341 actcaacgag atttaactgc tggaatcgta gggaaatcga ttggtttaaa aatgttacct
     2401 tcgcatgttg ctaatgctca tcaaaaagga gatatccatt accatgattt ggattacagt
     2461 ccttatacac cgatgacgaa ctgctgttta attgacttta agggcatgtt agccaatggc
     2521 tttaaaattg gtaatgctga agtggaaagt cccaagtcta ttcaaactgc aacagctcag
     2581 atctcacaga ttattgcgaa tgtagcatca agtcagtacg gcggatgcac agctgatcgc
     2641 attgacgagt ttttagcccc atatgcggag cttaacttta aaaaacatat ggctgatgct
     2701 aagaaatgga tcgttgagac taagagagaa agctatgctt ttgaaaagac tcaaaaagat
     2761 atttatgatg cgatgcagtc tttggagtat gaaattaata cgctctttac gtctaatggt
     2821 caaacaccat ttacttcttt aggatttggt ttggggacgt cttggtttga acgtgagatt
     2881 caaaaagcta ttttgaccat tcggattaat ggtcttggta gtgaacatcg cacggctatt
     2941 ttccctaaat taattttcac ggttaaacgt ggcttgaatt tagaaccaga ttcaccaaac
     3001 tatgatatta agactttggc tttagaatgt gcgactaagc ggatgtaccc ggatatgtta
     3061 tcttatgata aaattattga tttgacagga tctttcaaat ctccaatggg atgccgctct
     3121 ttccttcaag gctggaaaga tgaaaatggg caagatgtga cctcaggccg tatgaatctt
     3181 ggggttgtca ccctcaattt acctcgcatt gccatggaat caaatggcga tatggataag
     3241 ttttgggagc tgtttaatga gaggatgcta attagtaagg atgctttaat ttatcgtgtc
     3301 gaacgtgtca cagaagcaaa accagcaaat gcccctattc tttatcaata tggtgctttt
     3361 ggaaagcgtt tggagaagac agggaatgta aatgatctct ttaagaatcg tcgtgcaaca
     3421 gtctctcttg gctatattgg tctttatgaa gtggcgtctg ttttttatgg tggtcaatgg
     3481 gaaggtaatc cagatgctaa agcttttacc ttgtcaattg tcaaggcaat gaaacaggcc
     3541 tgtgaggatt ggtcagatga atatggttat catttctctg tttattcgac tccatcagaa
     3601 agtttgacag atcgcttttg tcgtttagat acggaaaaat ttggcattgt gacagatatt
     3661 acggataaag aatactatac aaattctttt cactatgatg tgcgtaagag tccgacacct
     3721 tttgaaaaat tagattttga aaaagattat ccagaagcag gtgcttcagg tggttttatc
     3781 cactactgtg agtatcctgt tttgcaacaa aatccaaagg ccttggaagc ggtttgggac
     3841 tatgcttatg atcgtgtggg gtatttggga accaatacgc ctattgataa atgctataat
     3901 tgccaatttg aaggcgattt taccccaaca gaacgtggtt ttacttgccc aaactgtggc
     3961 aataatgacc ctaaaacagt tgatgtggtc aaacgtacat gtggttactt ggggaatcct
     4021 caggcccgcc caatggttaa cggtcgccat aaggaaatct ctgcgcgtgt aaaacatatg
     4081 aatggttcta ctataaaata cccaggcctg taaactcaag ctgggggaga gcccttttga
     4141 tggaaatatg atatgcttaa aaggttgctt catgcaagca atcttttatt gtttaatggt
     4201 ttcttagcaa ttgtgagata agaataacta atccaaaacg actaattagc tgttagcaat
     4261 cggactataa gaagaaagag ataaggaaga aataatggga aaatatcaat tagactataa
     4321 aggaatgcag caggtagaac gctttcatga gaagcattct aaaaaaaaga cggataaaaa
     4381 atcccgcgtt caagaactta aggctcggtt tttagagaag tcaaaaaaac aggataacta
     4441 aagtatccaa taaagaaaga aggttgagta tgcttaatat tggtattgtg ggactaggtg
     4501 ccatttcaca aaaagcctat ttaccatata tgagacagct gagtgacatt acttggcatc
     4561 tatcaacgcg gaatgcagca gtacgtcagc aggtcggtca gttatttggt cacgctattc
     4621 tttacagtga tgtcaaggag ttgtcaaaga caagtttaga tggcgtcttt attcatgcgg
     4681 ccacatcggc ccacgcagag ttggctagtt tatttttaaa tcaggggatc ccagtcttta
     4741 tggataaacc tatagctgac aattacctga tgacaaagaa cctctatgac ttagccaaag
     4801 aaaataagac ttttctgatg gcaggattta acaggcgttt tacacctcgt gtcaaggatt
     4861 tgtcaatttt gtcaactaag cgtaaagtgg ctgctgaaaa aaatgacttg gaccggccag
     4921 gagatatgac ttttaagctc tttgatttct ttatccatcc tttagacaca gccttatttt
     4981 tgacagaagg gaccttacta aaagggcatt ttcaatatca tctggaagca ggcttactga
     5041 gtcaagttat ggtaaccttg atgaccgaaa gcatgacgac tacagcttct atgaatttac
     5101 aatcagggag tcgccgtgag gtaatggaag ttcaacgggc tgaagaaact tatcatttag
     5161 agaacttaga cgagttatct atttataaag gtactaaaaa aagggtgctt ggctttgctt
     5221 cttgggacac taccttgcac aaaagaggtt ttgaaacaat gatcgatgcc tttttagaag
     5281 ctattagcac aggcgtcaat cctgtcagcc ctgagtctag tcttttaagc cactggattt
     5341 gtcaacagat tgctgactct cagctttctt atggagagtt aacggtagag ttgcctaagg
     5401 attaggaatt gatatggaaa taagacgacc gactttaaaa gataaagatg ctgtattgtc
     5461 aatgattaac gaatttttag agcagaaaag tgctacagct gggttatggc attttaacgt
     5521 caatgacttc aactatgaaa catggttgga agattccttg cgacaggaaa tgggtttggc
     5581 cagtcaagga gtgcctgcta ttcaatatgt ggcgtttgat gagaaaaatc aagctttggg
     5641 atttttaaac cttaggttac gtttaaatgc ctcattactt gaaaaaggtg ggcatattgg
     5701 ttactctgtc cgtcccagcc agcgtgggaa aggttatgcc aaggagatgc ttaaacaagc
     5761 tgtcagctgt gcgatttcca agaatatcac gacaattttg gtaacttgtg atgagactaa
     5821 tgttgtaagc cgagcagtta ttgtggctaa cgggggtgtc ttggaagata gtcgaggtgg
     5881 aacggaacgt tattggattg aagaacaaag aggcgataag tgatggcaga aaagtgttgg
     5941 aataatccta agccaaagga atggcaggca gaggagttaa gtcaaggccg gattattgac
     6001 tataaggctt ttaactttgt tgatggtgaa ggggttcgta attctcttta tgtgtctggt
     6061 tgtttattcc attgcaaggg gtgttataat gctgcgactt ggtcttttaa ggcgggaatg
     6121 ccttatacgc aagaacttga agagcagata atgacggatt tggcacagcc ttatgttcag
     6181 ggactgacac ttttaggtgg agaacccttt ttgaatacgg gtatcttaat tcctctgatt
     6241 aagcgtattc ggcgtgaatt gccagaaaaa gatatttggt cttggacggg ttatacttgg
     6301 gaagaaatga tgcttgaaac accagacaaa ctggaaatgt tgtccttaat tgatattctg
     6361 gtagatggtc gttttgatat cacaaaaaag aacctcatgt tgcaatttag aggctcttct
     6421 aaccagcgaa ttatcgatgt tcaaaagtct ttggctgcta aagaagtgat tatctgggat
     6481 aagttaaacg atggggacca aacctttgaa caaattagtc gggaggattt gctttaagaa
     6541 gctgacttat ccacatgatt tttttgaaaa ggtcatgtga aaacaggtcc tttaagggtg
     6601 aattggggag aaagtgattg ttatttcctg gttttcccca cattatcctc atagttatcc
     6661 acaggatgtg tataagtttt agaattgtga ataaagacta aaaaagaggc ctaggcctct
     6721 tttttgatat agacaaattc atgatctgtt gataggtctt gatggtagta aaaaccagca
     6781 aagacaaggc ttttaaggct gtcaacagtt tggcaattat tttccataca ggcagtgaga
     6841 aatgcacctc gtgccttttt tgaaatggtg gaatgggttt tgaattggcc ctctttttct
     6901 gccataaact tgggacttat ccacaattgt ttacagtctt tggaaaagac atcgtcaaat
     6961 tcactggata aaagggaaat cacttgggga tgctctttgg caaactgatt ataacagggc
     7021 cgccagtaag acttgaggct ttgtccttca atttttattc tggtgtgaaa atcatggcgg
     7081 tgctctgcga taggatgatt agcgggaatg ataccgtaaa aggatgaggt gatgtaaacc
     7141 tgctgggtga ggtaagcctg ttcttgggta gtgagcttat cgcgcttgat atggcggtac
     7201 ataaggccat tgaacagttg gtaggcaggg taagccaagc tttgttgaga ggccatgtct
     7261 tgccagcgtt gctgttcttt tttagctgcc tcttctttga tacgatatga tttggccaag
     7321 tcctccgtgg tcatagctgc catgattttt aaaatggctt ggctgtcttg tggaaggagg
     7381 tgtggatgag attccttagg gatcgtcatt tcttttgcgg ttggaattaa aaaggttagc
     7441 atagtgttat tgtagtaaag ttacttgctt tctgtcaaga aaactagtct tgtccaagga
     7501 tgacgttcac acggatacct tcctcgtctt ctgtcgtgaa agaagaagaa tcttcttgta
     7561 aaatagctag gccgtgtaat cttgcttttt tcagagtagc tgaaaaaagc aggggcgtct
     7621 caatgtgaat ggtcaagaag gctaagcctg gggcaccttc ttggtgtttt ttgaggtaag
     7681 gggctgacca gtgattgaat gcaaggtgat gatggtagtt ccctgaagca atccagctag
     7741 cacttggaat ggtcatttta tcgcctaaat caaaaacctt ttgatagaga agtgaagaag
     7801 ccagagcatt tttgacactc agatggacat ggccaatgcg tgtgtcttga gctagtaaaa
     7861 agcgcttggg gatatctgtc aactgctcca atatgctttt ggtatccgtg ggctcagtca
     7921 caccaataat ttgaccattg tcgcggatat cccaatgctc aacagctttg tcatgataaa
     7981 tttcaatccc attaccctca ggatcgctga ggtagatagc ttcgctatag ccgtgatcag
     8041 ctgctccttc taaagagata cctctagtta agaaatgatt gagaacaagt cccaagctat
     8101 gacgatcagg aactaaaaag gctgtgtgat aaagaccata agccttattt gctggtaaag
     8161 gtgtttgtcg taactctaag ataacggttt taccgtctgt agtcaattga cgagatgtcg
     8221 tgtcttgtga gagaacctgt aaaccgataa tacttgtgta aaaggttgtc atctttgcta
     8281 gatcggtaac atttagagaa accgttccta aagagatggt tgagttgtaa gggtatgtca
     8341 tcctattacc tccaaaaact agttaaatct atcataatca atcagtttca aaaagaaaag
     8401 taggcacaaa taagtggtat aggcactaaa aagtaactca tttgttaacc ctatcttgtt
     8461 tctgttctct ctaatagtct ataatgggtt ataagttaca aaaagatact aagaggagct
     8521 gctgcctatg ctgaaaaaaa gaccggcttg tcccgtagaa acggccttat cggtaatcgg
     8581 gaataaatag aaattattaa tattaagaga cttgctaaag ggaccttgcg ttttgggcag
     8641 ttgaagtcct caataggttc ggtcagtcaa aaggtactta ctgcacaatt aagggctatg
     8701 gaagcagacg gattggttca tcgggaagtg tatgcagaag tgccacctcg ggtggagtat
     8761 tccttaacag aaactgggtt gagcttagct cctgttattg aagcgatgtc ggattggggc
     8821 caaacttacc aagaaaaaca tgccgattta tttgaagaag gctagaggaa agagttgtcc
     8881 gagcatactg agacttagag aagctgagag tttttaaaaa atgatattat caaattcttt
     8941 acagtttgat aaaattactt tttttctaca aaaagacttg cgctcatctc acgaatatga
     9001 taatataata tcaagtctgt ttgagaaaac agaagctcag gtcaagtaag tgcacactta
     9061 caataacaca gttgataatg gggaaactca gagtcaagaa aaagaaaagc aagccttgca
     9121 ttttgcaagg cttttttctg tctttatttt ggtctgcgcc gagcaaaatc taaaaattta
     9181 aatttttcca gtttatggcg actctcggtg aattggaatt ggttattatt ggaaaggtag
     9241 actttggatt tgacggaaac aacatgttgg tctgatccaa ggtcaagtaa aattttatca
     9301 cgatcggtta tttggtcaat ggtaacctct ttgagggcaa agtcaatggc gagatggagt
     9361 tccttttcca aatattgata aatagaatgc tctgcgattt cccatgtcat tattggcacc
     9421 aaagttttac taaggtaatc aatgtctaag acggaagcca caccctcaac aacgcgttgg
     9481 cgtgtaacac gccagaccaa gctgtttttg ctaaaaccgg tcaattttga aagtgtctca
     9541 tccacaatca gtttatcaat ggcaatgacg ttggtcttag aatctagatt tgagtaagag
     9601 acgagttcct gataactagt tagttctgag atagggaata tgatctgatg atgtttaatc
     9661 acttgggtgc cacgtccttg ttttttgagg ataagacctg cctttgtgag aagtgagaga
     9721 gccttgcgga cggtatctcg gctagcttgg tattgttgac tcaattctat ttcagtaggt
     9781 aaaaaatccc cttctttgta aaagtctttg tttattttta tttcgaggtc tttataaata
     9841 cgttcatact ttgtcatagg gtaaattacc tttccacttg tctatttttt tacagacaac
     9901 accttttatt ttaccaaaat aatggctttt ttggcacaaa caacttgcag acaaatttgc
     9961 aatcgattac aataaaggtg tcagtcagat tttatctaag aatttgaata tttcattttg
    10021 acgttgcttg ttaaaagcaa ctagaacaaa ggactagggg atgtcacatg ggaaaatttg
    10081 aacaggatgc taagagtctt ctaactgcta ttggtggtaa agaaaacatc aaggctgtca
    10141 cacactgtgc aacgcgtatg cgttttgttt tgaatgataa taataaggca aatgtcaaag
    10201 agattgaaaa aatctctgta gttaaaggga catttaccaa tgctgggcag tttcaggtaa
    10261 tcattggtaa tgatgttcca gttttttata atgactttac agctgtttct agtattgaag
    10321 gggtgtctaa agaagctgcc aaatcagcag ctaaaagtaa tcaaaatgcc ttacaacggg
    10381 tgatgaccat gttggctgag attttcacac ctattattcc ggcgattatt gttggggggc
    10441 ttattttagg tttccgtaat attttggaga gtgtgccttt tgaatttctt gggcagcagg
    10501 tcgaaaaagg gaaattagtt tttgatgcag ctggggatcc tgtttggaat acgattgtga
    10561 gggtatctcc tttctggtca ggggttaacc atttcttgtg gttaccaggg gaagctattt
    10621 tccacttctt accagttggg attacttggt ctgtgacgcg taagatggga accactcaaa
    10681 ttttaggaat tgtccttggt atctgtttgg tgtcaccaca attattgaat gcctatgcgg
    10741 tggcaggaac gcctgctgct gagattgcca aaaactgggt ttgggatttt ggtttcttta
    10801 ctattaatcg tattgggtac caggcacagg ttattccagc ccttttagct ggtctgtccc
    10861 ttgcttatct tgaaattttc tggcgtaaac ggattccaga agtggtttca atgatttttg
    10921 tgccattcct ttctttgatt ccagctttga ttttagcgca tacggtattg gggccaatcg
    10981 gttggactat tggtaaaggg atttcctttg ttgtgttagc tggattgact ggtcctgtta
    11041 aatggctatt cggtgctatc tttggtgcct tgtatgctcc gctagttatt actggtttac
    11101 atcacatgac aaatgccatt gatacccaat taattgctga tactgcaact cgtacaactg
    11161 gtttgtggcc aatgattgct ctttcaaata tcgctcaagg gtcagccgtt tttgcttact
    11221 atttaatgaa tcgtcatgaa gaacgtgagg ctgaaatatc gcttcctgca gcaatttctg
    11281 cttaccttgg ggtaactgag cctgcccttt ttggggttaa tgttaaatat gtttatccct
    11341 ttgtagccgg aatgatcgga tcaggtattg cgggtctctt atcaacaacc tttaatgttc
    11401 aggcaaatgc tattggtgtt ggtggcttac caggtttcat ggctatcaat gtgaagtaca
    11461 tgattccatt cttcatctgt atggcagtag ccattgtggt gccgatgttt ttaaccttct
    11521 ttttccgtaa atcacatatc atgactaaga cagaagatga agctaaacta cctgagacac
    11581 ccgtttcgga tgctcctgta gcaactgctc cacataagac tatgcaagga acagttatca
    11641 ctttaacaag ccctttaacg ggtgaagtta aagcgttgtc tgaagctgtt gatcctgtct
    11701 ttgcacaggg agttatgggc caaggtgctc ttcttcaacc gacagaaggg gtgttagtag
    11761 cgccttgtga tgctgaagta tcggtcttgt tcccaactaa acacgctatt tgtttggtga
    11821 cgactgaagg tttggaatta ttgatgcata ttggcatgga tacggttaac ttagatggtc
    11881 aaggatttga agctttggtg aagcaaggtg atcaggttaa ggctggacaa acattgattc
    11941 aatttgatat agcagctatt tctgaagctg gatacgccac tgaaacgcct cttgtggtga
    12001 ctaatcaaga tgtttttacg gtaactgttg aaggtagttt accgcgtcag attaaggtta
    12061 atgataagtt agcagtagcg gtgaaaaagt aggtttacta agagaaaacg ttcaggaact
    12121 gagatcagtt cctgaaacta ttttagggag gaaaactcat gacaattgat aaaaagaaag
    12181 tcgtctatca aatttaccca aaatcctata aggacacgac tggaaatggt gtgggagact
    12241 tgcgagggat cattgataaa ttgccttact tacaagaact aggaatagat atgatttggt
    12301 tgaacccttt ctaccctagt ccacaacgag acaatggcta tgatgtttca gattatatgg
    12361 cggtcaaccc tgattttggg acaatggctg attttgaaaa tttggtaaaa gctgctaagg
    12421 agcatcagat tgagttaatg ttggatatgg ttttgaatca ctgttccaca gaccacgagt
    12481 ggttccaaaa agctttagca ggagaccctt attatcagga tttctttatc ttgagagatc
    12541 agccgactga ttgggtttcc aaatttggtg ggaatgcttg ggcgcctttt ggagatacag
    12601 gcaagtacta cttacacttg tttgatgtga cacaggctga cttgaattgg cggaacccac
    12661 atgttcgtga ggaattggct aaagtggtta atttttggcg agataaagga gtgaaggggt
    12721 tccggtttga tgtgattaac ctgattggga aagatgaaga gctggtggat tgtccggtca
    12781 atgatggtaa gccagcttat acggatcgtc ctattactca cacttatctt catgatctca
    12841 atcaagccag ttttggtcag gatgattcgt ttatgacagt aggggaaatg tctgccacga
    12901 ctattgataa ctgtctttta tacacggctc ccgaacggga agagttgtcc atggctttta
    12961 atttccacca tctaaaagtt gattatgaga atggtcagaa atggactatt atggcttttg
    13021 attttgcagc gctgcgagac ttattccatg cctggggtga aggcatgagt cagggcaatg
    13081 ggtggaatgc cttgttctac aataaccatg atcaaccacg tgccctgaat cgttttgttg
    13141 atgtaacaca tttccgaaac gaaggtgcga cgatgttagc ggcttccatc catttgtcac
    13201 gaggaacgcc ttacatttat atgggtgagg agattggcat gcttgatcca gattttgata
    13261 gtatggatga ttatgtggat gtggaaagtc tcaatgctta ctcaagctta ttagtctcag
    13321 gtaaaagtgc agaagaagcc tttgccatta tcaaggctaa gtcaagggac aatgccagaa
    13381 caccaatgca atgggatgct agtgaacatg ctggctttac gactggtaag ccttggttag
    13441 aggttggcaa atcttatcga gacatcaatg tcgaaacaga aaaagaggga cgtatttttc
    13501 ctttctacca acgcttgatt gctttgcgta aggaactccc tattattgct gaaggggact
    13561 atcgggctgc ttttaaagat agtcaggctg tctatgcctt tgaacgccat ttaggtgacc
    13621 agtgtttgct tgttctcaat catttttatg ctgatgaggt cgaactggaa ttacctccac
    13681 gttatcaaca tggacaggtc ttaatcagca actatgagaa agtctctatt tgtgaaaaag
    13741 tgatgctgaa accttatcag acacttgcta tcttagctga aaactaacta aaagcctggg
    13801 gttaggcctc aggcttttgg tgattgttac gaaaaaagta gttttctcat atatttattt
    13861 taaaactctt attttttcta aataaaaaca attgagataa gttattttag ctaaattttg
    13921 gtacaatgga aaagattata agtagagttt aagataaaga ttctacaaat ttaaaatgat
    13981 ataaggagat acgaatgaca acttatcaag atgattttta ccaggctgtg aatggaaagt
    14041 gggctgaaac agcagttatt ccagacgaca agcctcgaac aggtggattt tcagacttag
    14101 cagatgaaat tgaggcatta atgctagaca ctacagatgc ttggttagca ggggatcatg
    14161 tccctgatga tgcaatttta gcaaattttg tgaaattcca tcgtttggtg gctgactatg
    14221 ctaaacgtga tgaagttgga gtaagtccaa ttcttccttt aattgaagaa tatcagtcct
    14281 taaaatcttt ttcagaattt gttgctaata tagcgaaata tgaattggca ggtttaccaa
    14341 atgaatttcc ctttagtgtg gcaccagatt ttatgaatgc tcagctgaat gtgctttggg
    14401 cagaagcacc aagcattctt ttgccagata caacatacta cgaagaaggc aacgaaaaag
    14461 ctgaggaatt gcgtggtatt tggcgtcagt cgcaagaaaa gcttttacct caatttggtt
    14521 tttcaacaga agaaatcaag gatcttttgg ataaggtaat tgagctagat aagcaattgg
    14581 ccaagtatgt cttgtctcgt gaggaaggct cagaatatgc caaattatac catccttatg
    14641 tgtgggctga ttttaaaaaa ctagctccag agcttccttt ggatagcatt tttgaaaaga
    14701 ttttaggcca agtacctgac aaggttattg ttcctgagga acgtttttgg acagaatttg
    14761 cagccactta ttactctgaa gccaattggg atttactcaa ggctaatttg attgtggacg
    14821 cggctaatgc ttacaatgct tacttgacga atgatattcg tgtggaatca ggcgcttatt
    14881 cgcgcgctct ttcaggaaca cctcaagcta tggacaaaca aaaagcagcc ttttatttgg
    14941 cgcaaggacc gtttagccaa gcgcttggct tgtggtatgc tggtcaaaaa ttctccccag
    15001 aagctaaggc tgatgtggaa agtaaggtag cacgcatgat tgaggtttat aagtctcgtc
    15061 tagaaacggc tgattggtta gcaccagcca cacgtgaaaa agccattact aaattaaatg
    15121 ttatcacgcc acatattggt tacccagaaa aattaccaga aacctatgct aaaaaagtga
    15181 ttgatgagag cttgtcattg gttgaaaatg cacagaactt ggctaaaatc acgattgctc
    15241 acacttggag taaatggaac aagccagttg accgtagcga atggcatatg ccagcccact
    15301 tagtcaatgc ttattatgat cctcagcaaa atcagattgt ctttcctgcg gcaatcttac
    15361 aagagccatt ttattcttta gatcagagtt cttcagccaa ttatggagga attggtgcag
    15421 tcattgcgca tgagatttca catgcctttg acaccaatgg tgcttccttt gatgaacatg
    15481 gtagcctaaa tgattggtgg acacaagaag actatgctgc ctttaaagag cgtacagata
    15541 agattgtggc gcagtttgac ggcttagagt cacatggtgc taaggtcaat ggtaaattga
    15601 cagtttcaga aaacgtcgct gatctaggtg gggtagcttg tgctttagaa gcgacacaat
    15661 cagaagaaga cttctcagcc cgtgacttct ttattaactt tgcgacgatt tggcgtatga
    15721 aggcccgtga ggaatacatg caaatgctag ctagcattga tgttcatgcc ccgggtgaac
    15781 tgcgaacaaa tgtcacctta accaactttg atgctttcca tgagaccttt gatattaaag
    15841 aaggcgatgc tatgtggaga gctccgaaag accgtgtgat tatttggtaa ttaggtagtt
    15901 gataaacctt caaatgcttg tgattataaa aatgactgat tctgtgaaac acaggatcag
    15961 ttttttgctt ccttattggt gtccgttttg acacaacaaa aagacaaccc tcaggaaaga
    16021 aggttgcctt tttttagact tatcagaaat aagtgattag ttgttaaggg cagcagccat
    16081 agtagctgca acttctgatt caaagtcgtt agcttttttc tcgatacctt caccaacttc
    16141 aaaacgtgca aaagcaatcg ctttagcgtt tactgagtca aggtaagctt caacagtttt
    16201 gctgtcgtcc atgatgtaaa cttgtgcaag aagagtgtaa gcttggtcaa ctttagtgtt
    16261 gtcaagcatg aagcggtcca ttttacctgg gatgattttg tcccagatct tttctggttt
    16321 gccttcagca gcaagttcag ctttgatgtc tgcttcagca gcagtaatca cgtcgtctga
    16381 taattgagct tttgaaccgt atttcaagaa tggaagtgct ggtttgtcaa ccattgcacg
    16441 cgattcgttg tcaagttcga tagcgtggtt caattgagca agttcatctt tgatgaattg
    16501 tgcatcaagc tcagtgtatg aaagaacagt tggtttcatt gcagcgatat gcattgatac
    16561 ttgtttagca agagcatcgt cgccgccttc gacaactgag ataaccccga tacggccacc
    16621 attatgttgg taagcaccga agtgttgctc atctgttttt tcaatcaaag caaaacgacg
    16681 gaatgagatt ttttctccga tggtagcagt tgcattaacg taagcttcag caagagtttc
    16741 acctgaaggc ataacaagtg caagtgcttc atcgttgtta gctggtttgc cttcagcgat
    16801 aactttagca gttgcgttta ccaattcaac gaattgagca tttttagcaa caaagtctgt
    16861 ttcagcgtta acttcaacaa cagcagcaac gttaccatga acgtaaacgc ctgttaaacc
    16921 ttcagcggca acacggtcag cttttttagc tgctttagcc attccttttt cacgaagaag
    16981 ttcaacggct ttgtccatgt caccatctgt ttcaacaagt gcttttttag cgtccataac
    17041 gccggcacca gatttttcac gtaattcttt tacaagctta gctgtaattt ctgccatgtg
    17101 tagtatcctc caaatgatat ttgttttggt ttcaaaaaac gagacagagc ggtttgcttt
    17161 ctgccccgtt tggttttcga ttgttaaaga caaacaaagt ttgccataag agttaggaac
    17221 tctgtgctaa ttaagcgttg tcgccttcga caacttcaac gatttcttcg attgaatctg
    17281 cttgagtgtc agcttcaaaa gcaacgtctg catcttcacc ttgacggcct tcgataatag
    17341 cgtcagctaa tttagcagtg attaatttaa cggcgcggat agcgtcatcg ttagctggaa
    17401 tgatgatatc gatatcatct ggatcagcgt ttgtatcaac catcgctaca actgggatac
    17461 caagtttttt agcttcttta acagcaattt gttctttatg tgggtcaaca acatacatca
    17521 cgtctgggat acgaggcata tcttcgatac cgcccaagaa tttttcaaga cgagcgcgtt
    17581 gtttgttaag aagtgcaact tctttcttag gaagaacgtc aaaggttcct tcttcttcca
    17641 tacgtttgat ttctttcaaa cgagcgatac gtttttggat agttccccag ttggtaagcg
    17701 ttccacccaa ccaacggtgg ttgatgaagt attggcctgc acgcgttgct tcgtcagcaa
    17761 ctgcttcagc agcttgtttt ttagtaccaa cgaacaagat gacagcatcg tttgctgcag
    17821 catcacgaac aaattcgtaa gcttggtcag ctaattttac agtttgttga agatcgataa
    17881 cgtggatacc gttacgctct gtgaagatgt atttagccat cttagggttc cagcgacgag
    17941 tttggtgacc aaagtgaaca ccagcctcaa gaagttgttt cattgaaatt actgccatga
    18001 gtagtttctc ctttataaaa tgttttttcc tcttccagac ttcgacttgc aggctaacct
    18061 agcggcaaca agcccacaat tggtctagaa tgagtatttg ccgcctacac gaccctacta
    18121 tattatcaaa aaaagaggtt aaaagcaagg agaaatgcta tggattccct catttttgag
    18181 atgactagct tctttgttta ttggtaagtg ttaagacaag cttttgctca ttttgggtga
    18241 cacttgccaa atcgttttat ttaagatata gtgaacttga ctaatttttg gaggcgtttt
    18301 catgaagaag ggtattcgat ttcaattgct tggcagtccc cacatttttc ttgatgacaa
    18361 agaacaattt tttgcctttg ccaaagcaaa tgctctcctt tattacttag tggttaatgg
    18421 atctgttagc cgcgaggtgg cggcgagtct actttgggaa aataagaaca cgcaaacagc
    18481 gaaaaagaat ttacgaaacg ctatctacca ggtcaataaa gtcttgcaag ctgatgtgat
    18541 tatttgtcca aatcgcaacc tgctggtttt gaataaaaca cttgatatca aaacagatat
    18601 taaccttttt ctggctgatc cgctagctca cttagaactc taccaagggg agtttttgca
    18661 gggcttttac cttaaaagtg gtgaggaatt tgatctttgg gtttcaaaaa tgcgtatgca
    18721 gtatgaacag gtatacctaa aagcgtgtta ccaaaaaatt gaagaaaagc tctctttaga
    18781 tgccattgaa gatgtcgagg aacatttaaa gcagcttatt gaacgtgatg aatttgaaga
    18841 gaaaaattat cagctcttga tgaggcttta tcagcaggga aattgtcctg gtaaggtcat
    18901 cgaaacttat tatcagttgg ctaatgtgtt ggataaggag ctagggattc agccaagttt
    18961 gcaaagccaa cagatttatc aggaagtggt cgctaaagat cgtaatgaac gcaaaatcaa
    19021 gcattttttg cgcaacagta atcatttttt ggggcggatt gatgagatta agcagctgga
    19081 aaactatttt gccaactgtt tggcctgcca agaggtagga gctctgctct taattggtga
    19141 tacagggatt gggaaacgaa ccctagccag acaggtctta gccaatcaaa cccaaacgtt
    19201 tcaaattgtc acagctaaat gttttcgtga agaggctatg gattccttat tgccttggcg
    19261 taatatctta gatggcctgg gagatttggt gattcaaaac cgcttattga ccaccaaagc
    19321 ttggaaggct gctcttaaac gctgttttcc tgtggcaacc atttttcaag aagataacaa
    19381 ccaacccttt atcaaggacc acaccagctt gttggtttcc tttattgttg atattttaca
    19441 acatttggca gaaatcaagg cgctggtaat ccttattgag gattgtcact ggatggatga
    19501 ggacagtttg accttgttgc aacgggtcat gaatcaattg gtccactatc cgattgcttt
    19561 tgtcttgacc aagcatctag gaacgactcc tgagctcggt ctttgtttga atactttgat
    19621 gagtcagggg cgtttagaaa gcatttgttt ggagcctttt aatcggcaag aaagtttggc
    19681 ttatattaac agtcaactgg gtagtcagcc agtgacggca gaagaaatgg agcacctcta
    19741 tcaagccagc caaggcaacc ctttcttttt gtcagaatac actcaggccc tactgcgtca
    19801 cgaaaaattt gtgcctttaa cgtctgccat taaggctaag ttgggtctta aactagctaa
    19861 tctaagtagt cgtgatgacg cattgttaaa ctatttgtct tgttgtcgga ggcctatccc
    19921 tctaaatacc ctcgctcaat tgatgttact gcctttagaa gaagtgatcg agatggtgga
    19981 taatctgggg cactactata ttttggtaga agaaagcgta ggagaggaag tgttgatttc
    20041 atttcgtcag cgaattattc aactctatag ttatgaccgt ttatctttgt caaaaaggcg
    20101 tttattgcac ggacaaattg ccaaacggtt agaagattta ctgcctattt tgacaccaag
    20161 ccctcactta ttagatgaca ttgcttacca ttatcaggaa tcacggcagg tgattaaggc
    20221 tttggaatac aaccttaact atctagatgc taccttgcca tttcagcatg agctgtttcc
    20281 catttattca aagagtattg gctccttgga aaagtcagat cgtgacgatc aacgcttaat
    20341 ggaagagcag tttgataaga ttcgtcaaag cattgcggat ttggaactga cctatgataa
    20401 taaccgtgat ttccagcagt tgcttattcg tttttcttac cttgaaggcc gttatgatat
    20461 tcgaacaggg aggtatcaag aagggattaa acacattcaa aaggtcatcg ctttggcaac
    20521 cgagctaaaa cagccctcct tcttgctaga aggctatcgc cagttaattc attactgtat
    20581 ccaagtggaa aacaagccag aaatgcgtta ttacactagt ctttcattgg aggcagcggt
    20641 ttctgctaat cattttgagg ccattgcgat tagtttgcgg ttaaacggtc tctatcattt
    20701 gattattggg gagttaaatg aggcagagcg tctgcttcaa cagtcgattg acttctttaa
    20761 ggtgacgcca ggcttgcaag ctaactatgc gattcagatt gctgctgcct tagattattt
    20821 gggggagatt gcccagattc gctatcagtt tgaaaaggcc gttgcttacc aaaaacaagc
    20881 cattgccttg accgaaaaca agccagctga gttatcggtg agtatttttt atattggatt
    20941 agggatttcc tacttttatt tagctgattt tgaacaagct gagcaaatct tgagtttggc
    21001 taaggaagct ttggtcaatc atagttatcc ttggaaagaa acgcaacttg aaatttacct
    21061 ggccatgatt caatggaaaa agggcaatta tcagccagcc ttgaccctac ttgattacag
    21121 ggaaaccttg atgtctaggt atcgcaatcc gcgtgacaag ggcttgattt tctatttgat
    21181 ggctgtggtc aagtaccaat tgatacgtca aggagatacc ctaagtcagc aggaaaaaga
    21241 aatggtagct cacctgttga cagaatcctt tgagtattat tatgaaattg ctagtactaa
    21301 cctcaaccct taccgagatt gtcatttggt gagtgagttg aacgatttgc gtcagcaatt
    21361 atctgctaaa agctaaggaa aaccctctga agtgaatcag agggttttag ctatgttgtg
    21421 ccataatctg tacgaggtaa aagataaagg tggctgctaa attggcggtg tggttatcaa
    21481 tatcgtgtgg tggtgaaacc tcaaccacat caaagccaac taattttccg ctagctgcaa
    21541 tgtgttgcaa aactaagacg gcaagatttg ggtcaacacc gagggactgg atagcactaa
    21601 ccccaggtgc agcaccaact gagaaacaat ccatgtcgat agtcaggtag accctttctt
    21661 gcccttctaa gaaacggtca atggctcggc agaccttttg atggcccatt tggtagatgt
    21721 cttgacctgt taaaaattga atgcccttgg attttgccac aaagtcaaat aggaaaaggt
    21781 tgttattatg ttcttgaatg cctaaaacga agtatttaaa gaggcgtttg tcagcaaccg
    21841 catcgtcaaa catttgtcga aagcctgtcc ctgaattagg gcctgtttgg tcgtaaggcc
    21901 ttaaatcaaa gtgggcgtcc atattgatga cagctaggtc atcacttggg gataggcttt
    21961 ggcgtaggcc taagtagtgg ccgtaggcgg cttcatggcc acctcctaag acgatgggtt
    22021 tgagattgag gtcacacatc cgtttgatgg ctttgcttaa actgttttgc agttgttcca
    22081 aagagcgatt ggggccgtca atgttaccca catcgtaaac cataacttgg tttcctaaat
    22141 gccaagggaa tttggcgagc tgggttcgta tggcagctgg actttcgacc gctccgacac
    22201 gaccattatt gatataaacc cccttatcac ttttaaagcc aatcaaggca aaatgtgtcc
    22261 cttcaaatgg ggttagtgag ctgtcgttaa ggtcaaggaa agtcatgacc atgccccatt
    22321 tggcagtata taagtcatcg tcgatcccac catgataata gctagtggtg gatgggtagt
    22381 aatcttctag catgcgcgtc atctccttta ggattatgat agcaaaataa aacttacagt
    22441 caacactttc ttggcctttg tcactggttt ttaggaatag cagagcaata aaatcgtctg
    22501 cttttggtcc cggttagtta gtctaaagag gccatgacct ctgccacagc ccctctagtt
    22561 aaagaagtac cttattcact aaaattggat actcaactca actgcctgct caaccgcttc
    22621 gaggaagctt gggtcttcaa tgactgctga tgccttgttt agttcatcgt agatttcgat
    22681 gtgtttatcg tgttcgataa agttgacttc cttgcggaag agatcgtagg caaccttagt
    22741 ccctttacct agttcatgat tttcaggttt gaaatcaagg gcttggcagg ctgccatgat
    22801 ttcagtagcc acgatgcggc gagaattttt aaggatttca aaggccttgc gagcagcggt
    22861 ggtgcccatg ctgacaaagt cttcttggtt ctcacaagat gggatagaat ccacactggc
    22921 tggatgtgcc aaaaccttgt tttcagaagc aagagaggca caggcgtact gggtaatcat
    22981 aaagcctgaa ttgagacctg ggtatttgac aaggaaggat ggtagtttgc tgagctggct
    23041 attgaccaaa cgttccacac ggcgttcaga aacatttcca atttcagaaa tggcgatgcc
    23101 taagaagtca aatggctgtg ccattggttc tccgtggaag ttacctcctg aaataacgtg
    23161 gccatcttta cagataattg gattatctgt gacagaattg atttcaatgt caactttgga
    23221 tttgacatag gcgatactgt ctttgctagc cccatgaatt tgaggcatgc agcgcaaggt
    23281 gtaagggtct tgcacacgag attgagtagc tacggttgtg ttttggctac cttctaggag
    23341 gtttcggata ttgcgggctg ttgccaactg gccgctttga gggcgaatgg tgtgaaggtt
    23401 ttcttcaaat ggactagtaa tcccgttatg cacttcaagg gatagggcac cagctaggtc
    23461 tgacagtttc aataattgaa tggcgtcata ggttgcaagg gcaccgattg cagtgagaac
    23521 agttgttccg ttgataaggg cgagtccttc tttagcggct aaagaaatct tgtcaatacc
    23581 agctttatca agagcttctt gaccagaaag aagctctcct ttgtagtaag ctttccctag
    23641 accaagcata ggaagcacca tgtgagcaag cggcgccaaa tctcctgaag cccctagaga
    23701 ccctttttca ggaatgtaag gatgaacccc tttattgagc agttccaaca gtttttcaat
    23761 ggtggataga cgaataccag aatacccttt gactagtgaa ttgatacgga tcagcatgat
    23821 agctctcacg gcatcttctg gcaatgggtc accaaatcca ctagcatggg tacgaatcaa
    23881 attttcttgg agttgaactg tatcttctgg tgagatgctc acgttacaaa gggatccaaa
    23941 accggtggtc accccgtaaa ccacccgttt ttcactgaca atgtcatcaa caattttacg
    24001 agaggcattc acagcttcaa tagcactatc atcaatgtga caggctacgc cttggcgagc
    24061 aatcgcaatc acgtcttcga tagtaaggct ttcgccatct aaattaatca ctcttgtcat
    24121 agtttttctc ctagatttgt tccttagggg gcatttggtc catttggtgg ttacgtccgt
    24181 gcataaggta gtacacacta cttgcaatga tgacaccaac tgcaccataa acaaagttca
    24241 ttgggttgtc accccaaatc ataactaaac taacgataac tgcaagaatt gggataatag
    24301 ggccaaatgg tactcggaag atcacattag catcgggatc gtccttccgt aatttcataa
    24361 cggctagtgc tgttggaatg tattggaaga agcggaaaac aacactgagt tttgctaagc
    24421 tttcaaatga gccagtgagt aggagtacaa tggcaattgc tcctgaaacc aagatagcaa
    24481 cgagtggcgc gccattttga ttttgcttgg caatagcagc tggtaagagc ccttcatcag
    24541 caatggcagc accgtaacgt ggcaccatga tggattctcc catgttaaga cctgtaatgg
    24601 aaattaaagc accgattgag accatccaag cgccagcagg gcctatcatt ttaacaaagg
    24661 catcttgaac aggtgcattg gtcatcatga tttgagagcc aagcatggca atggttccac
    24721 cgataatcag catatataag acagagacga tactgattga tcctaaaaga gcatgcggta
    24781 catttttttc agggtcacgc atttccccag cgacaataga gagggtttca aaaccgataa
    24841 agccatagaa tatataaaca gcagtattgg agatagcccc taagaggtta gtccctggtt
    24901 ccaactgaac aaatggggta aagttaggaa gcccgttttt gatgaagaaa agggtacagg
    24961 cacaaaaggc aacgattgga attaacttag caatggtggc tgtgatggtg acaattttag
    25021 aggttttcaa accagcgata ttcatcaaag atagtaagat gattaaccca atactaagtg
    25081 gaatgtgcca accttcaaag gcagggaaag taatgataaa cattctggca aacccagctg
    25141 ccatggctgc ccaagcgaag atagtaacgg tccaaccaag gaagccaacg ttaaagccaa
    25201 taaaatcacc aaaagctcgt ttggaatatt ggaaggctcc gccgtttttc ccaaaataac
    25261 cagagacttc tgcaaaacaa actgccaaca tgatggtcaa aatagctgtt ccaaacataa
    25321 cagcgatgga tgcagggcca aggcccttat aaatggccct aggtaagaga aaaataccag
    25381 agccgataac ggcattgatc ccgtaaagag tggcaccgct caagctaaac tttgcctgtt
    25441 ctctttcttg ttcgttcatg tgatttgacg ccataataat gctctccttt ttgtttgcaa
    25501 attgcgttca aatataatgg ataaggtcgc taggaaatga ggagatagtc ggtttaggag
    25561 gatccttctt gcacctaacg atagtgatga gctattggtt agcgatgaga aataggtagc
    25621 cttttgtaat gatgtgtagt gatttcattg gagaagaata ggcatgagta gtgtgatgcc
    25681 tatctttatc ccactaagtc ttataccata agcctgccca aacagctact ggagtttggg
    25741 cggggcttgt ttgattgagg caaactttta gatctgaaag gctggcctcc tgctcgatta
    25801 ccaacaagtg attggcttca agctcttgat tcgcctgatt ggtcacagaa taagtcagtt
    25861 tgcttagggc ataaagcagt tgacagtccg ctttaggtgc ctcaaatggt gtgtcagacc
    25921 agacgggtaa taattgccct tggtattggt catcatacat taaattgatg tcttggcagg
    25981 ttccacgact gacgattctg gtatcgcctt caaacgcata gggttgaaaa ggagctaggg
    26041 aagtctcttt agcatgactc aaatcactta atgtgatggg cttgtctagg ctcattagaa
    26101 tcctgtgata gccatcaagt cgggtaaagg ttgtctgtcg tagggctaca gttgcagttg
    26161 agagacgata agagaattct ctctttttgt aatctccatc ttcgggataa aggaacaatt
    26221 ggttggtttc accgccagac cagtcagttt ggaggtaatc agagggcgct ttgatggtta
    26281 cctttgtcat ttgttctctc cttatttcca attagaatag tcctgtgatg ttgccctcct
    26341 cgtcaatatc aattgtttcg ctggcaggta cttttggaag gccaggcatg gtcatgatag
    26401 cacctgttag ggcaacgata aatcctgctc ctgcggacac tttaaggttg ctaatagtca
    26461 ctgtaaagtc agttggtgcg ccaagttttt tggcatcgtc tgagaaggaa tattgggttt
    26521 tggccatgca aattgggtag ttgccaaagc cgaggcgttc taagtcagcc agttcacgtt
    26581 tggctgctgg gctcaaggtg atgcctttac caccgtaaac tttggtaacg attttagtca
    26641 gtttggtttc aatgctatcg tcttcctcat aaacaaagcg gaattgattg tcttgctcgg
    26701 ctagtgtcac gactttttca gctaattcac ggccaccagc tccgccattt gcccaaacat
    26761 cagaaatcac aacgtcaacg ccacgtttgt cgcaggcatc atagacagct tgtaattcag
    26821 catcggtatc aagcgggaat ttattgatcg ccacgacaac tggaaggcca tagacgtctt
    26881 ggatattagc caaatgtttg tcaaggttag gtaaaccatc cacaactgcc tgaacatttt
    26941 cagtagccag gtctgctttt ggaacgccac cgtgcatctt aagggcacgt atagtggcta
    27001 ctaggacaac ggctgctgga cgaaggcctg acctgcggca tttgatgtca atgaattttt
    27061 cagctccaag gtcagcgcca aatccagctt cggtaacggc ataatcgcca tatttcaagg
    27121 ctagtttggt ggctaggaca ctattacagc catgggcgat attagcaaat gggccgccgt
    27181 gaatgagggc tggtgtgtgt tccaaggttt gcacgagatt aggatgaatc gcatccttga
    27241 gcagagcggc tagggcacca ccagctttca agtctttagc tgttacaggt tcaccttgga
    27301 agttgtaacc gatgataatt ttttcaaggt gggctttgag gtcagaaata ttttcggata
    27361 ggcacaggat tgccatgatt tcagaggcga cggtaatgtc ataaccatct tcacgaggga
    27421 ccccgttgac cttaccttgc aagccgtcaa caatatgacg aagctggcgg tcattcatat
    27481 ccaccacacg tttccaagtg atacgtctag aatcaatgcc taggctattg ccatggtgaa
    27541 tgtggttatc aatcaaggca gctaataagt tgttggcgac accgatggca tgaaagtccc
    27601 ctgtaaagtg aaggttgatg tcttccattg ggacaacttg cgcgtggcca ccgccagcag
    27661 ctcctccctt aaccccaaaa acaggaccaa gagaaggttc acgaagggca ataactgctt
    27721 tttttccaat ggcagaaaga gcatctacca atccaacaga agtggtggtt ttgccttcac
    27781 cagctggtgt tggtgagata gcagtgacaa gaatgagttt gccatcaggt ttgtttttta
    27841 aggcgaccag ttgacgggca tcaatttttg ccttgtactt accatagaga cagagcgctt
    27901 ccttgtcgat ccctaattga tcggcaacct tactgatagg ttccatagtg acagagttgg
    27961 ctatttcaat atctgataaa accatagttg ctcctttact tgttaaacaa tatcgagaat
    28021 tttcgtgtag atgtcatctg ccaaatgaca gcccttgtct aataaggctt gtcctttttg
    28081 gcgatagtcg gtaacaaagt cttcatcttt gatgccagac agattaatca aaacattcaa
    28141 ccaagcgcct tgtaaacctg cttttaagtt taaagcagca actcctaagt cactagcagc
    28201 atttgtatta gacttaccga cagctgttgc agtgatctca agtgcttcga ccatgagggt
    28261 catcatctca aaaggtgatt gtgcagctgt tttcaaagcc ttttgcatgg cagttcgtct
    28321 ggcagccttg tcttcgtcag tctcttttgg catgtcgaaa acgtcagaaa ccaggttgaa
    28381 ggcttcggtg tctttgtcaa tggcatctaa taagtcctgt tgcaagcgac tacttttggt
    28441 atgaaggtct tcaatgatat cttgataatc agcatacttt ttcttaccaa gggtcaattc
    28501 acagaccatc ttggtcaagg aaatgccatt agcgccagag agagcagcag cagaaccacc
    28561 acccggagca ggggcatctg agccaaggac tttagcgaaa tctgttaagc ttaaatcaac
    28621 taatcccata agacaccccc tagcctagca aatggttttc aagaatctgt ttatggtagt
    28681 caaagtcctc aacttgcaag tagtattcag ccacatcgat taaggcttta gctggcgcta
    28741 agcctatgat ttcagaacca ataacattca caccgtagcg acgcgcttca aatttgatgg
    28801 tttcaaaagt acggtaaaga gaacattttt caaagttaac catgttcatg gaaacttggg
    28861 caatatgacg gtcttctaac atgacaccga tagccttaca atatttgtag ccaccacctg
    28921 aaccgcggat aattttcgca attttatgag caatgtcgat attgtcagta tccaaattaa
    28981 cattgaaagc aaccaatggc atacgagcac caacggcagt tatcccagca gttgggtgaa
    29041 tcttacgatc tccgtaatca ggtgcccaat cctcttccaa cagtttttct ggcatgcctt
    29101 cgaattgtcc tttacggact ttggccaggt tttgacgttc tgggcgtgtg gcagaatctt
    29161 cataaaggaa gattgggatt ccaagttcac ggttaatccg ttctgcgact tgtttggaaa
    29221 tctcaacaca ttcttgtgta gtgatgtctt tgatcggaac gaatgggcag acatcggttg
    29281 ctcccatacg agggtgttca ccatgatgtt tggtcatatc aatgttttca gaagcgtatt
    29341 tcaccagttg gaaagctgct tcttgaatag actggtcatc tccaaccaag gtaaacacgc
    29401 tccggttgtg gctcgcatca gaagagtagt cgagaagggt cactccagga atacttttgg
    29461 ccgtcgctac caaaccatcg ataacagcct gattttggcc ttctgagaag ttgggaatac
    29521 attcaacaat tttcgccatg ttaatctcct tttatgtcat tgagttactc attaagggaa
    29581 taggttacct actttagata acgcttacat ttttagctag cagttattag tgaaataatt
    29641 gatctaccgc tgaagtcaca aggtcatcat cagccaagta tgggatagtg atgtgatcag
    29701 tacctgcatg gagacggttg tattcaatag cggtttcaat agcgtgctca ttgcgagccc
    29761 aattgcgacg agcaacacca cccatggtgt cccaagcaat agcagattta ataatctcat
    29821 caatgcgttc gctgccatct agaacaagtc caaagccgcc gttaatggct ttaccgatac
    29881 cagttccgcc accgttatga agagccacta aactcatacc acgcgcagcg ttaccagcgt
    29941 aacattgaac tgccatatca caggtgacat tggaaccgtc tttaatgttt gaggtttcac
    30001 ggaatggtga gtcagtacca gacacgtcat ggtggtcacg gccaatcatg acaggtccaa
    30061 tcttaccttc tcggaccaat tcattaaatt taagggcgat agtcacacga ccaatacagt
    30121 cttggtaaag gatacgggct tgtgtgccga cgaccaattg atttttctca gcatcacgaa
    30181 tccagttata gttatcacgg tcttgatagc ggcggtcagg atcgatagct tccatggcag
    30241 ctttgtcagt agccaccaag tcttcgtgtt taccactcaa gcagacccaa cggaaaggtc
    30301 catagccata gtcaaaaagc ataggtccca tgatatcttc cacataggat ggccagataa
    30361 agccgtcttt gtcgttacga ccattcttag aaatttctgt aataccagag tcgtaaacag
    30421 acttcataaa ggcattgccg tagtcaaaga aataggtgcc attttcagtt aacgtcttaa
    30481 tagcttcaaa atgccgtgcc aaggtatcat caaccatttg gtggaaggta tccttgtctt
    30541 ctgccaggag ccgggttctt tcgtcaaagc taatacctac tgggcagtag ccaccgtcat
    30601 aaacgttgtg acaagaggtt tggtcagaca aaagatcaac atgaatctgc ttgtcattga
    30661 cgtactctaa aaggtcaaca atattaccat ggtaagcaat cgaagtggac tccttagcat
    30721 ctatggcttt tcgggctaat tgcagagctt cttcagggct ctcagcaatt tggctaaccc
    30781 agccttgcga atgacgggtt tcaatccgag attggtcaac ttcagcaata atggcaactg
    30841 atttagcaat ttcagcagcc ttaccttgtg ccccactcat gcctcctaaa ccagatgaga
    30901 taaagagttt accggtcaaa tcaccatcgt cagccactcc aagtttgaga cgaccagcat
    30961 ttaagagagt attaaatgtt ccatgaacaa tcccttgtgg gccaatatac atccaaccac
    31021 ctgcggtcat ttgaccatag ttggtgacac ccatctcttc ggcgatttcc cagtctttca
    31081 tgttgtcgta ttcacccacc aaaaggccat tagtaataat cacacgaggc gcttcaggtt
    31141 tggatttgaa aagaccaact ggatgaccag actcaaccac caaggtttgt tcatcagtca
    31201 tgacctctag gtatttttta atcaaacaat attgcatcca gttggcacaa acagaaccag
    31261 tttctccata agtgactagt tcgtaagggt acaaggcaat ttcaaaactc aagttattgt
    31321 caatcatgac ctgcatggcc ttggcagctg tacaatttcc cttgtactcg tcaatgggtt
    31381 tgccgtaaat gcggtctttt ggacgccatc tgtaaccata gatgcgtccc cttgttttga
    31441 gttcttccaa aaattctgga atgacttctt cgtggaactt cgtaggtaca tagcgtaggg
    31501 cattttttaa ggcaatttcg gtctgagcct gggtcaatcg aaaacctctg tctggtgctc
    31561 ttcggatacc ttctttgaac acagtctttt ccggtaaaac atcgtctaat ttaacagtca
    31621 tagcggcagc tatgtcagtt tcactgtaaa atgacataga aaactcctcc tcaactcctt
    31681 tttattgtcg agattagtct aacttagtct agtctataaa aagtcaacca cgctttgaaa
    31741 tgcgaaaaaa gtctaaaaaa aaatcaaaac ctcatttttt gactaaaatt tgacgcttaa
    31801 tcagtacact tgaggcatga cagataaagt cagtcagagg ttaattgttg ttaccaaagt
    31861 tgcaaagatt gcaactattg agtgggtgag gggggactag taatggctat taatcagttg
    31921 acaaacgatg ttaaaaaagg aggtttttat ggttgctgat gtcttattaa cacattttaa
    31981 tcaactattt tgtctaaatg atccaggtca tcctttaact ggtcaagaaa tgaaaaaagc
    32041 cactatcgtt gaagatggct atatagctat caaagacggc ctcattgtgg ctcttggttc
    32101 tggtgaacca gatgctgagc ttgtcggtcc acagactatt atgcgttctt ataaaggtaa
    32161 aattgcaacg cctggtatta ttgactgtca tacccatttg gtctatggtg gcagtcggga
    32221 acatgaattt gccaagaaat tagcaggggt gtcttacttg gatattttag ctcaaggtgg
    32281 tggtatttta agcacggtga gggccactcg gtcagccagc tttgacaacc tttatcaaaa
    32341 atccaagaga ttgctagact acatgttgct tcatggagtg actactgtcg aagcgaaaag
    32401 tggctacggc cttgattggg aaacagaaaa acgccaactg gatgttgttg ctgctttaga
    32461 aaaagaccat cccattgatt tggtgtctac gtttatggca gcccatgcga ttcctgaaga
    32521 atacaagggg aatcctaagg cttatctcga tgtgattatc aaggatatgc ttcctgttgt
    32581 taaagaggaa aatctggcag aattttgtga tattttctgt gaaaaaaatg tttttacagc
    32641 tgatgagtcc cgctatctgt taagcaaagc caaagaaatg ggcttcaagc ttcgtattca
    32701 cgcagatgaa attgcgtcta taggcggagt tgatgtcgca gcagagctca gcgcagttag
    32761 tgcagagcat ttgatgatga taacagatga tggtatcgct aagttgattg gtgctggtgt
    32821 tattggtaat ttgcttccag ccaccacctt tagtttaatg gaagacactt atgcccccgc
    32881 tcgcaaaatg atcgatgccg gcatggctat cactctctca acagatagta atccaggcag
    32941 ttgcccgact gctaacatgc agtttgtgat gcaattaggt tgttttatgt tacgtttaac
    33001 accgattgaa gtcttaaatg ctgttaccat taatgcggcc tactctgtca atcgtcagga
    33061 gagagttggt agtttgacag ttggtaaaga agcagatatt gccatttttg atgccccaaa
    33121 tattgattac ccattttatt tctttgccac caacttgatt caccaagtct ataaaaaagg
    33181 acaactcaca gttgaccgag gtcgtattct ttaaaaaatt tcaaaaagaa gctttgagcg
    33241 ttagctcaaa acttctttta aatatgctgt tttattgacg aatcaagtag tcaaaggcac
    33301 cgatggcagc agtagcacca gaccccatgg aaataatgat ttgtttataa gctgaatcag
    33361 tacagtcccc agcagcaaag ataccaggaa tattggttga cccatgttta tccacaatga
    33421 tttctccgcg gtcggttagg ttgacaccac tatctttgag ccaagctgtg tttggaacaa
    33481 gaccaatttg aacaaagacc ccttcaaggt caaggtgttt gtcttcaccg ctatcacgct
    33541 cagtgtagtt aagacctgta acatggtcct ctccgacaat atccttagta gcaacatttt
    33601 tgatgatggt catattgtta gtcttagctg cgcggtcttg aagcactttg tcagctttaa
    33661 gttcaggcaa gaattctaaa acgtaaacgt gtttagcaag accagccaaa tcaagggccg
    33721 cttctaaacc ggagttacca ccaccgataa cagcaacatc tttgccttca aagagaggac
    33781 cgtcacagtg agggcagtaa gtcacccctt tattacggaa ttcatcttca ccaggaacat
    33841 taatgttacg ccatttggcc ccaagagcta agatagcagt tttggcttgt agaaccgcac
    33901 cattagctag agtaacctcg atgttttctt ttttctcaat agaagtagct agttgtgctt
    33961 tgataatatc aacatcataa gacttagtat gggcctccac ttcggccatt aattttggtc
    34021 cttcagtgta aagggtacca atcatgtttt cgatgccgac cgtttccatg acctgaccac
    34081 caaaggtttc agcaagtaaa cctgttttta gtcctttacg agctgcatag atagcagcgc
    34141 tattgcccgc agggccacca ccaataacaa ggacatcata gaggccttta tcagcaaagg
    34201 cttcctcagg aagtgggcca gcgacttgtt ctaagagttg ctcaatggta gcacgaccag
    34261 aagtgaattc ttccccgtct aaaaagacag tagggacaga cataatgcct ttggctttca
    34321 cttcatcttg gaacatgccg ccttctacca tagtgtgtga aatcttgtcg ttcaagacgg
    34381 acataatgtt taaagcttga acaacatctg ggcagttatg gcaggttaag ctgacataag
    34441 tttcaaaatg taacggacgg tcaatggcct tgatgcgatc aataacatct tgatccactt
    34501 ttggagcacg tccagatact tgcaagagag caagaataaa ggacgtcaat tcgtggccta
    34561 aaggaagacc agcaaagaca actccactat catgaccttt tttcgcaacc ttaaagcttg
    34621 gttgtcggtc taaagtgatg ttttcaatag aaatacgctc agacatagca gctatttctt
    34681 ccacaaagtc tttgactttt tgagactgct cattgtcacc aagggaaact tgcaaaacaa
    34741 gatcagcttc taacagggtg aggtattggg caagttgttc tttaatatca ggacttaatg
    34801 ccatagcttt cctcctaaaa tttattaaat tttaccaact aaatcaagac tcggtgtcaa
    34861 agtttcagcg ccttctttcc atttagctgg acaaacttca cctggatgtt tacggacgta
    34921 ttgggcagcg tgaattttat caatcaaggt gctagcgtca cgtccaatac catcagcatt
    34981 aatttccatc atttggataa taccatctgg gtcaacgata aatgttccac gttgagcaag
    35041 tccgtcttcg ccaagcactt caaaggcttg tgaaataagg tgtgaagggt caccaatcat
    35101 agggtatgtg atagtgccaa ccacatctga atcatcatgc caagctttat gaacaaaatg
    35161 agtatcagta gagacagaat aaacttctac accaagagat ttcagtgttt cgtattgctc
    35221 ttgaaggtca ccgagttcag ttgggcaaac aaatgaaaag tctgctgggt agaaacaaaa
    35281 aactgcccat tttcctttaa cgtcttcatt tgtaacagtg atgaattttc catcgtgata
    35341 agcttgagct gaaaattcag caatttcttt tccaattaga gacatatagt tgtcctcctt
    35401 ttttatagtt ttatacttgt attataaaag aacaacaaga ttatgtctac tcagaaaccc
    35461 ttgattttac tgggaaatca gcgattgttt tctgacaatt cagttgtgaa ataaatcaca
    35521 ttaattaaaa tgattctaaa taagccgaag acgccgttaa atcaaaggtt aatttaatta
    35581 taatctacag aaaatataat tgttattaaa gcgtttacaa aaaaactttt ttgattccgt
    35641 taaggcaact taatattatg gttacctaat cactaatatt gtaacctatt ttggcatgag
    35701 atcagggaat ggctgttata ttaattggat atgtcttgtg caaatagtgc ttgacggatt
    35761 tgtggaatta gggtaaaata atctttgttg tggcggtata gccaagtggt aaggcacggc
    35821 tctgcaaaag cttgatcgtc ggttcaaatc cgtctaccgc cttttatata caaaacaagc
    35881 cttgattaac ttcgtgaaaa cgttgttaaa tcaaggtttt tattttttgc gacaggataa
    35941 aaaaagagaa aaaagaaata aagtcggtca aatttcccga agatgtcttt tatagcctga
    36001 ttattaggta tgaaaaatac tatggccaaa attggtaaac gattgcaaat aaaggtcaga
    36061 gttcttaccc ccttaaacga tatgcgttaa aagttagttg aactgccgtg cacctaacga
    36121 tagacacggt gatgtgagag cgagtagagt tgaatctcta ctcgtttacc ttaccatagt
    36181 cagctttata aagtaaccac ccattacaat gcaactatat tcttaatgtt tttaagcatg
    36241 ttattgacaa gtgttataaa atgtgttact cttagtgagt aaattagttt ttgagttagt
    36301 atttgtgttt caacatcttt atttctctct atttttacaa atgattttta gaaaggaagt
    36361 ggatgtatat ggcacaaggt acagtaaaat ggtttaacgc tgaaaaaggt tttggtttta
    36421 tttcaactga aaacggtcaa gatgtctttg cacatttttc agcaatccaa actaatggtt
    36481 ttaaaacgtt agaagaagga caaaaagtgg catttgacgt cgaagaaggt caacgtggac
    36541 ctcaagcagt caatatcact aaattggctt aatctggtta aagtaactaa agggaagcag
    36601 atgttggaaa cagcaactgc ttttttgatt tctaccagtt acctttaatg attaagagtt
    36661 gcgtttaagg tcttgtattt gttataataa tagtcagttt tagtcaaaat gtattgacgt
    36721 ggtgctacta agtttttaga gtagcccgca agcaaaggag tgacagcatg ccaaccaaaa
    36781 atacttcaga cagcattgaa gagtatatta aagaattatt agctaagtca ggaatagcag
    36841 aaattaagcg gtccatgcta gcagattcgt ttcaagttgt cccaagtcag atcaactatg
    36901 tcattaaaac ccgttttacg gagagtcgag gctatgaagt agagagtaaa cgaggtggtg
    36961 gaggctatat tcgtattgcc aaggttcatt tttcagacaa acaccatctg attggcaatt
    37021 taatggcaac tattgaagac tgtatcagtg agcaagtttt cacggactcg atacaattgc
    37081 tttttgacga acacttattg acagagcgtg agggaaatat cattttggct gtggcgtctg
    37141 atgatgtttt aggaactgat ggttcaacta ttcgtgcacg aatgctctat cgcttattgc
    37201 aacgaattga cagaaaggga agcaattaat gattatgtat tcaacgaaga tgcaagacat
    37261 ttttagacag gcgcagttcc aagctgctcg ctttgatagc cattgcctgg aaacttggca
    37321 tgttttgtta gctatggtag ctgtagacaa ttctttagca aatatgattt taagtgaata
    37381 tgatgcccaa gtcgccatag aagaatatga agctgcagct attttagcca tgggcaaaac
    37441 ccctaaggaa cagttgtctc gtgtagactt cagacctcaa tctaaaactt tgactaactt
    37501 gttagctttt gcgcaggcta ttagccaaat cactagggat caagaagtcg gctctgagca
    37561 tgtcttattt gctattttat tgaatccaga tattatggcg agtcgcttgt tagaaatagc
    37621 aggctatcag ataaaagata gcggcaatgg gcagccgcga ttagctgact tacgaaaagc
    37681 aatagaacgt catgcaggtt acagtaagga aatgattaag gctattcacg aactacgtaa
    37741 gcctaaaaaa acgaaaacac aagggacctt ttcagatatg atgaagccac caagtacagc
    37801 tggtgagttg agtgatttca caagagattt gactgaaatg gcaagacaag gtttgttaga
    37861 atcggtgatt ggacgtgacc aagaagtatc tcgtatgatt caggtactaa gtcgtaaaac
    37921 gaaaaacaat cctgtcttgg taggtgatgc aggtgttggt aaaactgcgc ttgcttatgg
    37981 ccttgctcaa cggattgcaa atggcgctat tccttatgaa cttaaggaga tgcgtgtcct
    38041 agaattagac atgatgagtg tggtagcagg aacccgtttt cgtggggatt ttgaagagcg
    38101 catgaatcaa atcattgatg atattgaagc tgatggtcag attattcttt ttgttgatga
    38161 actacatact attatgggtt ctggcagtgg tattgacagt acacttgatg cggctaacat
    38221 tttaaaacca gcattatcgc gcggcactct tcatatggtt ggagcaacaa ctcaagaaga
    38281 atatcaaaaa catattgaaa aagatgcagc tctttcgcgt cgttttgcta aaatattaat
    38341 tgaagaacct aatacagaag atgcttatca gattttgatg ggcctaaaat tatcttatga
    38401 gacctaccat aatgtctcga tatcaaatga agcagttaaa acagctgtaa aaatggcaca
    38461 ccgttattta accagtaaaa atctccctga ttcagctatc gatttattag atgaagctag
    38521 tgctgctgtg caaaacatgg tgaaaaaatc agcacctgag actttaacac caatagacca
    38581 agctcttatc aatggtgata tgaaaaaagt atctcgcctc ttagctaaag aagcaaaagg
    38641 tcagatgaga aaaccaacac cagtgacaga agatgatatt ttggcaacct tgagtaagtt
    38701 atcgggaatt ccacttgaaa aactgacgca agctgatagt aaaaaatacc tcaatttaga
    38761 aaaagaactg cataagcgtg tgattggtca ggatgctgct gttacggcta tttcaagagc
    38821 cattcgtcgc aatcagtcag gtattcgaac aggaaaacgt cctattggat catttatgtt
    38881 tcttggccca acaggagtag gtaagacaga actagcaaag gcccttgcag aagttctctt
    38941 tgatgatgac gcagcgctta ttcgttttga tatgtctgag tacatggaaa aattcgcagc
    39001 gtctaggctt aatggagcac ctcctggtta tgtcggctat gatgaaggag gtgaactgac
    39061 acagaaagtt agaaataaac cttattcagt cttgcttttt gatgaagtgg aaaaagcaca
    39121 tcctgatatt tttaacgtcc tccttcaagt attagatgat ggtatattga ctgatagtcg
    39181 tgggcgtaag gtcgattttt caaatactat tattatcatg accagcaatc ttggcgcaac
    39241 agccctgcgt gatgataaaa cggtcggttt tggggtcaaa ggcattcacc aagaccatca
    39301 agctatggag aaacgtattt tagaagaatt aagaaaaact taccgcccag aatttatcaa
    39361 tcgtattgat gaaaaagtgg tctttcatag tctgacccaa gataacatgc gtgatgtggt
    39421 taaaatcatg gtacagcccc tgattactac attggcagaa aaaggtatta cccttaaaat
    39481 tcagcctttg gccttgaaac atttgtccga ggtcggctat gatgagcata tgggggcaag
    39541 accattacgt cgaacgctgc aaactgagat agaagataag ctatcagagc ttattctttc
    39601 tcgagaattg acaagtgggc atacgctaaa aattggatta tcacatggca aattaacgtt
    39661 tcacatagct taatttccat ataaaaggtg gatcatcctt gatgtcacca aaaaaagagg
    39721 ttattcttac aaaaataact tcttttttct tgactatttt tgaccaagtg ataaaataga
    39781 atataaagtt agcactcgat gaacatgagt gctaacttta ctaaagattc ttttattgga
    39841 ggaaaatttc atgttaaaac cattaggtga ccgtgtggtc gtaagatttg atgatgaaaa
    39901 agagcagaca gtcggtggtt ttgtccttgc aggcactcat aaagagtcaa cacgaaaagc
    39961 gacagtcctc gctgtcagtg aaacgggtgt tcgcactatt acaggtgata gcgtgctacc
    40021 ttcagtttca gtgggtcaag aggttttagt tgaaaatggg catgatttag aagtaaccgt
    40081 agatgatgag aaagtttcta tcatccgtga atctgacatc gttgctattg ttacaaaata
    40141 aaacgacaaa tctctaaata gaaagaagga ttgaatatgg caaaagatat taaattttca
    40201 gcagatgcgc gtgctgccat ggtgcgcgga gttgatatgt tagcagatac cgtcaaagta
    40261 acgcttggtc ctaaagggcg caatgttgtt cttgaaaaag cttttggttc tcccttaatt
    40321 actaatgacg gggtaaccat tgctaaagag atcgaattag aagatcattt tgaaaacatg
    40381 ggagcaaaat tggtgtctga agtggcttct aaaaccaatg atattgctgg tgatgggacg
    40441 actactgcaa cagttttgac acaagccatt gttcatgaag gactaaaaaa tgtgacagca
    40501 ggtgctaatc caattggtat ccgtcgaggc attgaaacag caacagcaac agctgttgaa
    40561 gccttgaaag ccattgctca acctgtatct ggcaaggaag ctattgctca ggtcgctgca
    40621 gtatcatcac gctctgaaaa agttggagag tatatctcag aagctatgga gcgtgtgggc
    40681 aacgatggtg tgattaccat cgaagaatct cgaggtatgg aaacagaact tgaagtggtt
    40741 gaaggcatgc aatttgaccg tggttacctg tctcaataca tggtcacaga caatgaaaaa
    40801 atggttgcag accttgaaaa cccatttatc ttaatcacgg ataaaaaagt gtcaaacatc
    40861 caagacattt tgccactact tgaggaagtt cttaaaacca accgtccatt actcattatt
    40921 gcagatgatg tggatggtga agcccttcca acccttgtct tgaacaagat tcgtggtact
    40981 ttcaatgtgg ttgctgtcaa agcgccagga tttggtgatc gccgtaaagc tatgcttgaa
    41041 gatattgcta tcttgacagg tggtacagtg attacagagg atctaggact tgaattaaaa
    41101 gatgctacaa tgacagccct tggacaggct gctaagatta cagttgataa agatagcaca
    41161 gtaattgttg aaggttcagg aagttcagaa gctattgcta accgtattgc actgattaaa
    41221 tcgcaattag aaacaacaac ttctgacttt gaccgtgaaa aactacaaga acgtttggcg
    41281 aaattagctg gtggtgtagc tgttatcaaa gtaggagctc caacagagac agctttaaaa
    41341 gaaatgaaac ttcgcattga ggatgctcta aatgccacac gtgcagccgt tgaagaaggt
    41401 atcgttgctg gtggtggaac agcacttatt acggtaatcg aaaaagtagc tgctcttgag
    41461 cttgagggcg atgacgctac tggacgtaac attgtgcttc gtgctctaga agagcctgta
    41521 cgtcaaattg ctttaaatgc tgggtacgaa ggctccgtag ttattgacaa gttgaaaaac
    41581 agccctgcag gaacaggatt taatgctgca acaggtgagt gggttgatat gattaaaaca
    41641 ggaatcattg accctgtcaa agtaacacga tcagcgcttc aaaatgcagc ttctgtagct
    41701 agtcttattt tgacaacaga agcagttgtt gctaataagc ctgaaccagc agcaccagcg
    41761 ccagcaatgc cagcaggtat ggatccagga atgatgggcg gcttctaagc tctctatagc
    41821 attaaggatt atgaaaaaga agttgagact aaaggtctgc ttcttactat gaaaaaagaa
    41881 caaagattgg atttcgactc atgatatccc atctttgttt ttttagttgt gatataaaat
    41941 gccaatcttt gtggttacag acttttaatg tattggaaaa tatattgttt ttctttgtca
    42001 tgtgctatca tgaagtcaat gaaaagttat tcccatatat gcgtggtgga ggtctgtgat
    42061 gaatcatttt ggagagattt ttaaaacctt tagagaatca aggggattac gattaaaaga
    42121 tgtcgcaaag gctggtatat caacctctca gctgtcgcgt ttcgaaaaag gggagacgga
    42181 cttaaccata tcgacattta tgctgatttt ggatgaaagt aacatgccca ttgatgagtt
    42241 tatgtatgct gtccatgatt ttcatcgtga caacacaatt caagatagtg atggcttgaa
    42301 gcagttactt catgctcaac tagcatcaac tgataagaag gagatgttca cggatatctt
    42361 ttggcatatc cagcatgtct aagtctgcta tggcatgcta ttttgggagt ccctcacgcg
    42421 actctgtcag tagctctcct tcaaaggatt cacatagaaa gtcgtaatag acatagcagt
    42481 caggcttgat aaagctagaa atactcttta attgaaggtt taaagctgtc agacctatct
    42541 cttcttttag ttctcataaa gccgcttcaa agaaagattc acagggctcg actttacctt
    42601 ctggttggat ccatcctggg aagttatcgt gttgtctatg gagtcataaa atcatatcgt
    42661 tatgtttgac acacatattg ccccagtctc taaccgttgc tatcaccaga ttcaccacct
    42721 tttagtataa aaaaaagggg tgaaagaggt ttcttgttgt ttttttggct taaggtttct
    42781 ttaagtctta tctagtatac taatgtcatt ccttaacagg ataagtattt ggttgtagaa
    42841 gtatcgtctt aaactaacgc tatctcaacc gattcccatc ttattcaccc ctcctatacc
    42901 gataaggtct cacaaagtgt gagaccttat tttttgactt cagctctagt tatggagaaa
    42961 cttgttgata caagcttttt tgggttatgg tattatgatc tattcaagcc tttcttgttt
    43021 ttgggttttt ctttaaccaa cttggcttca atagctttta agcgtttgaa ggttttttca
    43081 gctcgagcca tggagaccgc gtcagctttt tcttgggcag ctgtaggatc tgtttgcacg
    43141 agttggttaa gttctttgtt ggtttggtct tgttcggcta tccaggtttt ttccaagcct
    43201 ttcatctcat caatcacttt agttccaaat gattttggat gagcagccac gagatcatta
    43261 atgtgtgaca ccgtccaata ccatgactta tcgttatatt gggtgctttt ttcttgatag
    43321 gcttcatagg ttctactgat attgccaagg tatggcaagt aaggggcgtt acgaggactg
    43381 ccaatagata gccacatgac accaccaccc aattcagcag ggatgtcttt tttcagttgg
    43441 aaaatatgag cttccatgac attaggattt gagatgggat aagcataacc tttaacagct
    43501 tttttggatt ttggtttacc cttaccgtct aatgccatct gatcaagtgg tttaagatcc
    43561 agcccctcaa aacgattacg ttgcagtttc atcgcatctt ctagactaaa ggtcttatca
    43621 gtgctttgga gcaactcata attgctgtct ttataagtta cttttgaatc agggtcaagt
    43681 gatttaatcc ctgagaaaga gcgagagcgg ttggcatcgt ttagtggcgg attgtaagat
    43741 ttggcaatat gaaatttacc atcaacttcg gtataagatt tggctttttt agcgactttt
    43801 tccacatctt ctgaggcaat cgtattttcc ttatcgttga aatcgacatg tccgagatag
    43861 aaggtatttg gaaaaacagc gtatttatca tctgggaatt tgatggcaac atattggtga
    43921 ccagagagaa tttccatgta ccagatgccg tctttgtcag ccaaggtaac aatatttcct
    43981 tcagcagctc ctttttcagt gactatttta gcaatcaatg cgacaccttc acgggctgtt
    44041 ttgacgcttg gtaaaatgac actggccata gatgattccg ctaagccatt tttgacgtaa
    44101 ggatcaattt tttggatggc atcattagct gaagctgata ctgttgcaga catagagacg
    44161 ccaaactcat taaaaccagc ttcgtcataa acgcctttgt taggtgttac atcaggaatc
    44221 gcactatagc gataagaatg ctcaggcaac gggtactcaa aaccattaga gaggtctttc
    44281 catttttcgc cagcaggatt gtcctttgct agacgtacaa tgaaattttt attatggtgt
    44341 ggctcaagat cttctgttcg accataaaga agagaaccgt ctttggttaa atctttgcca
    44401 ataataaaac cagtacaagc ataactaaca ctttgaagcg aaaaggctgt cagaatactt
    44461 aaaactccaa gtgatatttt tttgtttatc atgcgaatcc tcctagtaaa cgataacgct
    44521 ttcacagaca ttataaaatg ctctttttaa aaattcaagt cttttatgaa gtgttttgaa
    44581 attgttagct atctaaatat tatgagaatt ctctcttgaa ttttggctta acggccccta
    44641 aaaacgtata ggcagtgaac tatctaggtt tcttcgaaaa tccattagcc atttatgata
    44701 taatagtaaa gaaaaacata gaaagttggg gtctgttgat gaccaaacca tttcatcata
    44761 agaaactaaa acaaataact ataatagctg caactagcct ttttttattc ctgatcggtg
    44821 gtgcctttta ctactctaaa aatcattgta ttaatgccta tcttaaagct cgatcggccc
    44881 aatcaggacc agtttttgag aatatcaaag catatctagt ctgggatgat actaatgagc
    44941 agatcacaaa tgacgaggcg atgtatacta agtttagaag gtatagtcag aaagaattga
    45001 ggcaaaaaaa gcaggattta aaagccgcta gtcaagatag tgccgttcaa gtaaagtctg
    45061 ttggtcgtcg tttttggatt tttcctgatt atcggattgc cataaaaccc atggatttaa
    45121 cgataaaaac gaatgtgcct caagcagacg ttcttttaaa tcaaaaaaaa gttgctgttt
    45181 ctgattcaga acagttctca gtcaagcttg atcggctacc aacggcagaa tataccgcaa
    45241 gtatcagagg caaacacaac gggcgaaaca ttaaagtcaa taaatcatat gatggtgata
    45301 atcccgtgct agatttgagt gtgtctttta gaactttttt ggtaacaagc aatgctaagc
    45361 aaggagatct ttacttcgat gataaccata ttggcacatt aaaagatggt caattacaag
    45421 tagaagatta ccctgttaca gaaaacgcac aagcttatat gaaaacaaca ttcccagatg
    45481 gtgagttaag atcacaaaaa tatgctctag ctgatgttga agaaggagca accctggaga
    45541 ttttagttac agatctttta gaagaggaca aagcagggga gctattagta tcagcttttg
    45601 atcagctgat gcactacctc agtacaggtc aagactcatc taacttacgt agcgtctttg
    45661 aggcagggtc tagcaacgca ttttataggg gattgaaaga gtccataaaa gcgaaatttc
    45721 agacagatac aagaaaagcc agccgtctca atattccatc tatccttttg acaacaatga
    45781 ctcaagtggg caaaacaact tacgtgcttg atttcacagc tacctacgaa tttttgtatg
    45841 acaactcaac agatcctgag cagcatacct ctggacatat taatcaagac ttgactggaa
    45901 aagtgactgt aaaaaaagtt ggacagcatt accttatcag ccagtccggc tccaaaaata
    45961 ttactgttgt taaagaggac aatcaactca aagcgccatc tgtctttcct gagtctattt
    46021 tgggaacgtg gacaggccaa gccaatggtt tgagcatcca tatgtctcta gcatcagatg
    46081 gaacaattac gactaaagtt gaagatcaaa aaggcaaccg ttctaaagaa actcggacag
    46141 ctaaaattag taaagttgaa gacaaaggca atggttttta tctttatacg ccagatcctg
    46201 gaagtgacat aagcgcctta gttccagaag gaggattggg gggtgcaaat gtcaaatatg
    46261 cttatggttt caaaatatct ggtaaaacag cttctccagt ggtgtggcag gcagcattaa
    46321 cacatgaatt tgattatacc aagccacttt cgggagtaac tttgcaaaag caaccataaa
    46381 ggatgcaaag tcacaaagaa cagtagaaac aatgttatca ctcaaataca gtgctatgaa
    46441 aacagataaa ctcaaaaggc taggagatta tttcctagcc ttttgagcgt ttaagactgc
    46501 gtcaaatgta gctgatttag cttgcacgca aatgtcttct tgggttagag ggtgtttcaa
    46561 acgtaattga taagcatgga gcatcagtcg agcacaatct ttttttccat tagaatacaa
    46621 aggatcacca aataaaacat gaccttgatg ggctaaatgg actcgaattt gatgagttcg
    46681 tccagtttgt aattgacaat tgagtaagct tgccgttttg tggaagtttt tgactagagt
    46741 tacctcagta atagctttct tgccatttat cggatcgaca acacgttttc tgcggtcatg
    46801 tcgatgacga ccaattggat gatggtaagt taccctagga ctgtctaagg atccgtgaac
    46861 tagtgccaaa tattctcgat ggatgtctct tttttctaaa agacgattaa ggattggtaa
    46921 gataaaaggt gttttagcaa ataaaatggc cccacttgtt tccttatcca gacgatgaac
    46981 cacatagcag gtctgtcccg tgtaagcaga cacgtggttg agcagcgcca actctgttgg
    47041 atcattgccg tgtgttttca tcccttcagg tttgttaaca ataatgatgt gctcatcttc
    47101 ataaaggcag gttacttttt cggcctgccc catcacgata atcttttcag gataatcttc
    47161 gtgatcgaaa aaaagtttga cctgatcacc gtatttaaca caactttgcc agttaacagg
    47221 atgaccatta ataagaacat gttttttagt tctcagaaaa tgcctaattt tacggggaat
    47281 taacaattgt tcctctaata atgctttgac cgtcaattct tcaaagggat ttttcagtgt
    47341 gacagtaaac ccctttgatg gtttatttgt tgtcttcatt gagccagtta tggtattttt
    47401 caacaaggtt gatagccatt tgggtggcaa gagcagcaga gaaagcttca gtaccttcac
    47461 gctcgtcatt agctacctcc aagcgagtct catcgtaaat ggcttttaga ctttctgcgg
    47521 ataaggtttc tttaaaagct tggaatttat tcattggtta aacccgtcct tctatgttta
    47581 atgtgagctc ctgattaatg caaggaattc aatgctatta tagcatgttt ctaatcaaaa
    47641 cgtgccactc aaaaaggtaa aaacgttatt ttgctaatcc atctaataag aaagtgtctt
    47701 aaataagacc tcttgataga gtttgtaaca aaaatgatat gaaactaggt gctaacgcag
    47761 aaatagaaaa caactaacgt gttgcgaagt tggaacagtc ataaaaaata gcaagataaa
    47821 acttatcaac acacagttac ctaagacgat gagtcaaaca ggtatgttct ttcaaaacaa
    47881 ccccatgagg ttgaacgacg tatcggaaaa atacggatta gtttggcctt atgataggta
    47941 tttctctatc gtaaaagaag tcaaccaaag gtttttaata taaaatatta agaaaaattg
    48001 ttataattat gataaaaaca taatcgtaaa atagaggaaa aacaatgaaa acaattagac
    48061 gttatgatgt taacgaagat agagggcata caggccttgt agaagcagga gacttctatt
    48121 atttaaacta ttgtgtcggc aatgtcggac aagacattga aagtcagatt aatggagcct
    48181 ttgatgagat ggagcgccga ttagcattgg tggggctcac attagatgca gttgttcaaa
    48241 tggattgtct atttcgagac gtttggaaca tacctgtgat ggaaaaaatg attaaagagc
    48301 gctttaatgg cagatatcct gctcgaaaat cgattcaaac ggaatttgca catcacggtg
    48361 gaccacaagg actactcttt caagtggatg gtgtggctta ttcaaaacat atttcgatga
    48421 cctaatcaag gttactttaa gatcatagtg gtataataac gttatgagat ttctagaact
    48481 tttacaaaag aaattttttc ctaaagcata tcaggaaaaa caattcttaa tgcatcaaaa
    48541 agcgcgttta acgccacaac acaatcaaaa gcagtattcg ccaaatgccc atcatttgga
    48601 ctcatcagct accaaaaact cagaacaaga ccctgcaata gctctgcaac gcagtagagc
    48661 ctatgaagga agccctaaaa gtcggcccgc ttggttgcaa aagctggaag ctgttttgcc
    48721 gtctcctcaa catccaattc ggcgtttttg gcgccgctat cacatcggaa aactgctaat
    48781 gattctgatt ggaactcttg tcttactctt aggatcatac ttgttttact tatcaaaaac
    48841 agctaaagta tctgatttac aagatgcctt gaaggctaca actgttattt atgatcacaa
    48901 aggagagtat gcaggcagtt tatctggtca aaaagggagt tatgttgagc tcaacgctat
    48961 ttcagatgat cttgagaatg ctgttattgc cactgaggat aggacttttt acagtaatag
    49021 cggtattaat cttaaacgct tcttattggc ggtagttacg gcgggccgct ttggaggtgg
    49081 ctcaacgatt acacagcaac tggctaaaaa tgcttatctc tcacaagatc agacaattaa
    49141 acgaaaggcc agagagtttt ttttggcgtt agagttgacc aaaaaataca gtaaaaaaga
    49201 tattcttact atgtacctta acaactccta ttttggaaat ggagtttggg gagttgaaga
    49261 tgccagtcaa aaatattttg gaaccacagc tgctaactta acattggatg aagctgccac
    49321 attagcaggt atgctcaaag gacctgaaat atataaccct taccattctc taaaaaatgc
    49381 tactcaccgt agagatactg ttttaggagc gatggttgat gccaaaaaga ttacccaaac
    49441 aaaagctcag caagctagag cagtagggct aaaaaatcgc ttagctgata cttatgttgg
    49501 taagacagat gactacaaat acccatccta ctttgatgct gttattagtg aagcaatagc
    49561 aacttatggt ctttcagaaa aagacattgt taataatgga tacaaagttt acaccgagct
    49621 agatcaaaat taccaaactg gcatgcagac gacttttaac aacgatgaac tatttcctgt
    49681 ttcagcttat gacggtagct ctgctcaagc agctagtgtt gctttagatc ctaaaacagg
    49741 aggtgttaga ggtctgattg gtcgtgtgaa tagtagtgaa aatccgactt tcagaagttt
    49801 taactatgcg actcaagcaa aacgtagtcc cgcatcaaca atcaaaccac tcgtggttta
    49861 cgcgccagcc gttgcttcag gatggtcaat tgaaaaagaa ctaccaaata ccgttcaaga
    49921 ttttgatggc tatcagccac ataattatgg aaattatgaa tcagaagatg ttcctatgta
    49981 tcaagcatta gcaaactctt ataatattcc agcagtttct acattgaacg atatcggaat
    50041 cgataaagcc tttacctatg gtaaaacatt tgggttagat atgagctctg ccaaaaaaga
    50101 gttgggggta gctttaggtg gcagcgtgac aaccaatcca ttggagatgg ctcaggcata
    50161 tgctgccttt gccaataatg gagtaatcca tcctgcgcac ttgattaacc ggattgaaaa
    50221 tgccaggggt gaagtgctta aaacctttac tgataaggct aaacgtgttg tcagccagtc
    50281 tgttgcagat aagatgacag ccatgatgct aggtaccttt tcaaatggaa cagcagtcaa
    50341 tgctaacgta tatggctata cactagctgg taaaacaggg acgacagaaa ccaacttcaa
    50401 tcccgactta gcaggcgatc agtgggttat tggttatacg ccagatgttg ttattagtca
    50461 atgggtagga tttaatcaga ccgatgaaaa tcattatcta acggattcaa gtgcaggcac
    50521 ggcctcagct atttttagca ctcaggcatc ttacattttg ccttatacca agggcagcca
    50581 atttcatgta gataatgcct acgctcaaaa tggtatttca gctgtttatg gagtcaatga
    50641 aacaggtaat caatcaggag ttgacactca atctattatt gatggtttaa gaaaatcagc
    50701 acaagaagct tcgcaatcac tatcaaaagc agtcgatcag tcagggttac gtgataaagc
    50761 ccaatctatt tggaaagaga ttgttgacta ttttagatag cttgcagtat tttagagatc
    50821 gtgttaaaat aatagttacg gaggcgttat ggcacagaaa aaagcgagtc tagcgtgtgt
    50881 cgaatgtggc agtcgtaact actctatcgg agtgagtagc acgcctaaac caacacgtct
    50941 agaagtaaat aaattttgca aatactgcaa aacatatacc ttacacaaag aaacacgtta
    51001 aaaaggagag cctgatggga ttcattagcg ggacttttaa agtcttaaaa gacacaacat
    51061 ggccaaatcg taaacaacgt tggaaagatt ttatctcagt tcttgagtac acagctttct
    51121 ttacggtgat tatctacatc tttgaccagc tcttagcaaa gagtgtatta gcactgatta
    51181 atttattcta ggtcaagatt ggtagaaatg ataagcttgc ttggaaaagc ctaggctggg
    51241 agtattccca gccttttttg tagtatcaat aatctgatta gtaagctttt ttaaagccca
    51301 tactggtttg agctattcaa aagcataaag gtaaaggcaa tgtagcaacg atctccaaac
    51361 caagttcact aaattagctt gtaacagagt caacgcataa acagcctggc ctcacttgct
    51421 tagcacatta aaaatagcaa tgaatattat ggttgaggaa aacagcctga tagtctgtta
    51481 aatcttcggg atgataagcc ttgacctcag ccatctcata ctccctacct agaagtttgt
    51541 acttgttttc tccaaattga tggaaaggta acagttgcac ttggtcaatc tcaagctgat
    51601 taaagagctc tgagaaggct ttagcatcgt ctagtgaatc attaaattgg ggaataacag
    51661 ggatgcgcaa gacgatttct tttccagctt gaaaggcata atgaatattt ttgataatca
    51721 agtcattacg aaccccagtc actttttggt gtctgagctg attataatgt ttcaaatcgg
    51781 tatagataaa gtccacgtag tcaataaggg tgacaaattg ctcgtgtttg gcaaaggcgg
    51841 tggtttcaat tgcggtgtga agacctgctg ctttggctgc ttttaacagg gctaaggcaa
    51901 agtcaaattg ggcaaagatt tcccctcctg atagggtcat gcccccacct gactcttcgt
    51961 agaaatcaag gtctttaagg acttcttcga tcacctcgtc cacggttttt tcctctccaa
    52021 ctattttagt attaagccca tcacttgtta acatctgctc aggcgctttt tgttgggatt
    52081 cgggattggc acaccaagga catctcaagg ggcaaccttt taaaaaaacg gttgtccgaa
    52141 taccagggcc gtcatgaata ctaaaatgtt ggatgttgaa aacaataccg cgatcagtca
    52201 taagtgtgaa ttcctttcgt tgtaaaacca tcataccaga taaacgtaaa taaatcaatt
    52261 acgaatgaaa gtaaatatcc cttttctttt aagaaaataa ctggtacaat gaaagggagg
    52321 tgaatgatga atcgattaga acgtattatt caactggttt cccagaagaa aaaaatagat
    52381 gtgaacagtt tatcagagca attagacgtt tcgaaagtaa ccattcgaaa agaccttgat
    52441 aagcttgaaa gtaagggctt gttgcgacgg gaacatggct atgcggtact aaacagtggc
    52501 gatgacctca atgtacgctt gtcctacaat tacaacatta agcgacggat tgcagaaaaa
    52561 gcagctgaat tggtgcaaga taacgatacc attatgattg aatctggctc aacctgtgct
    52621 cttttggcag aagtgctttg ccagaacaaa cgaaatatta aaatcattac caattcgtgc
    52681 ttcattgcca actacattcg tcaatatagt agctgtcaaa tcattttact gggcggttat
    52741 taccagccca attcagaggt gactgttggt cctttattga aagaaatgat ttcccttttt
    52801 catgtcaatc gtgtctttgt tggaacagac ggtttcaaca aagatcttgg ctttatgggc
    52861 aaggacatga tgcgctcaga aggggtgcgt tacatggcag atgctgctga ggaagtggtg
    52921 attttgaccg attccagcaa gttttcaaaa accagtctgg tacaccagtt gtcattagct
    52981 gatgtcaatc gtgtcattac agaccaggca ctagacaagc aaacacaaga gttattaagt
    53041 gctagtggtc ttgttcttga ttttgtttct tagaaaatag gtggctagat gaaagaagaa
    53101 cgcagacggc tccttgccaa ggtggcttac ttgcattatg ttcaaggcaa gagccaaacc
    53161 ttgatttcaa aggaaatgaa tatctaccga acaacggttt gtcggatgtt agcaaaagcc
    53221 aaggaagaag gcattgttcg gattgaaatt gccgactatg atgctgattt atttgcttta
    53281 gaagaatacg tgcgacagca gtatggcttg gaaaaactag accttgtgcc caaccaggtt
    53341 gaagataccc caatggatac cttgacaaat gttgctaaaa cagcagctga ggtttttaga
    53401 catgttgtta aagatggcga taagatcggt ctgtcctggg gagcgactct ttcttgcttg
    53461 atggatgagt taaatccaaa agcgatgaaa gatgtgttta tttatccttt ggcaggagga
    53521 cctagccata ttaatgccaa ataccatgtc aataccctgg tttaccgctt ggctcgcatc
    53581 tttcatggta atagcgcttt tatgaacgct atggtcattc aagaagacaa acacttggct
    53641 aagggaatct tacaatctaa atactttaac gacattttaa caagctggga ccagctagat
    53701 cttgccttag taggaattgg tggggagcct aatagccttg agcagagcca atggcgtgat
    53761 ttattaacca gctcagatca tgaccaactc aaatatgaaa aagccgttgg tgaagtttgt
    53821 tgccgtttct ttgatcaggc aggtcagcca gtttacactg gcctacagga tcgaactatt
    53881 ggtatttcgc tagaacagtt gaggcgtgtc cccaaaacaa tggctgttgc aacaggtaaa
    53941 cacaaggcta aggcaatatt ggcagcctta aaagcaggtt ttatcaatta tctagtgacg
    54001 gataaagaaa ccatgctagc tgttttagcg ttagatgaag atattgatct taataacgtt
    54061 cttctttaat agaaattcaa agatactatg atatttatag aggcccaaga ccaaacggtc
    54121 agggcttttt tgtttgatgt gttgatgaaa cagagattgc tcaaatgtgc agttaacgca
    54181 ttggcacaaa agtgcattaa ccaaaatata gcacaaaata tattgaccct aaaaacaaaa
    54241 atgatacaat aaacttacca acgaaatgta aacgattaca aacacaataa catcaccttc
    54301 gaaaaaaaga ctcattgccg ttacatcaca tgaaaaagaa aaaaaaggag acaccaatgc
    54361 aagttattgt accagatcaa atcattatgg gcttaatttt aaatgcaggc gatgccaaac
    54421 aacatatcta ccaagctctg aaatgtgcta aagaggacga ttatgccact agtgaaaaag
    54481 aaatggcctt agcagatgat gccttattag aagcccacaa tttacagacc cagtttcttg
    54541 cccaagaagc tagtggtaat aagtcagaga ttacagctct ttttgttcac tcacaggatc
    54601 acttgatgac gaccattaca gaaattaatc tcatcaaaga gattattgac cttcgtaaag
    54661 aattggcaac caaataatat ttcattcata aaaaggagat tgacatgatt aaaattggat
    54721 tgttttgtgc agcaggattt tcaaccggca tgttggtgaa caacatgaaa gtagctgctg
    54781 aaaaaaaagg cattgactgt cagattgaag cctatgctca agggaaatta gcggactatg
    54841 caccattact tgatgtggca cttttaggcc cacaggttgc ctatactctg gatcaatcag
    54901 aagctatttg taaagacaat gatatcccca ttgcagttat cccaatggct gattatggaa
    54961 tgttagacgg taacaaggtg cttgatttag cccttagcct tgttaaagaa taggagtcaa
    55021 tcatggcaaa aatgaatatg caaaacatca tcatgccaat catgacattt gtgaatatgc
    55081 gcggcatcat tgccttaaaa gacggtatgt tagccatttt acctttgacc gttgtgggga
    55141 gtcttttcct gattgctggg cagattcctt tccaaggggt taatgatgcc attgctagtg
    55201 tgtttggtgc tgactggaca gaacccttta tgcaggttta tcatggaaca tttgctatta
    55261 tggggttgat ttcctgtttt gcaattggct attcttatgc taaaaactca ggtgttgaac
    55321 ctctcccttc aggggttctg tccttgtcag ccttctttat tttattgaga tcatcttatg
    55381 ttccagcaga aggtgaagct attggagatg ctatcagtaa ggtttggttt ggtggtcaag
    55441 ggattattgg tgctattgtg attggtttaa cggtcggagc tgtttacaca acatttatcc
    55501 gtcgtcatat cgtcattaaa atgccagatc aagtgccaca agctatcgcc aaacagtttg
    55561 aagccatgat tccagccttt gtgatcttta ccttgtcaat gcttatgtac attattgcca
    55621 agtcagtaac aggtggtggc acctttattg aaatgattta tgatgtcatt caggtaccgc
    55681 tgcaagggtt aacgggttct ctttatggcg cactaggtat tgccttcttt atttcctttc
    55741 tttggtggtt tggcgtgcat gggcaatctg tggtcaatgg aattgtcact gctcttctct
    55801 tatcaaatct agatgccaat aaggccttga tggcagcagg tgagttatcc ctagacaagg
    55861 gtgcccatat tgtaacccaa caatttttag actctttctt gattctatca ggttctggca
    55921 ttacctttgg tttagtggta gctatgatct ttgcggctaa atctaaacaa tataaggcct
    55981 taggtaaggt tgcagccttc ccagccctct ttaatgttaa tgaaccagtt gtctttggtt
    56041 ttccaattgt aatgaatcca gtcatgttct tgccatttat cttggttcct gtcttggcag
    56101 ctctcacagt ttatggcgcc attgctattg gtttcatgca gccctttgca ggagtgaccc
    56161 ttccgtggtc aacaccagcc attatctcag ggttcatggt tggtggctgg caaggagcta
    56221 ttgtgcaaat tcttatactc atcatgtcaa cgttggtgta cttcccattc tttaaaatcc
    56281 aagataatat ggcttatcaa aatgaacaag ctactgaaga gtcatgattt agcgtccaca
    56341 caaattcttg agaccatctc cagttagagg tggtttttta gaaaaagaag agcgatttat
    56401 caggcctata ttgcacaata gtgcaaaata aagtgactat ctcttcttat ggttaaggat
    56461 acgcaaaagt cgcaatatat gataaaatag ttacgaaaga aacatttata atttcgtaag
    56521 aaagaaggag accccgcatg actgaaacaa aaagccctta ttttggacat ttaacagaca
    56581 gaatgactca ctatcgtgaa gctgtgttag acaagaaacc ttatattgat gctgagcgtg
    56641 ctattttagc cactgaagcc tatcaaaaac accaaaataa gccagcaaac ctcaaacgcg
    56701 cttacatgct tcaaactatt ttggaaaaca tgaccatcta tattgaggat gaaagcctca
    56761 ttgctggtaa ccaagcctct tcgaacaagg atgcgccgat tttcccagaa tacactctgg
    56821 aatttgtcct caacgaactt gatctttttg aaaaacgaga tggggatgtc ttctacatta
    56881 ccgaagaaac caagcaacag ctccgagaca ttgccccatt ctgggaaaac aataacctgc
    56941 gtgctcgctg cggtgtcttg ctaccagaag aagtgcaagt gtacatggaa acaggtttct
    57001 ttggcatgga aggcaagatg aactctgggg atgcccattt agcggttaat taccaaaaac
    57061 tcttggaaca cggcttaaag ggatttgaag aacgggcacg agctgccaaa gctgcgcttg
    57121 atttgaccat tcctgaaaac attgacaaat accattttta cgactctgtt tttattgtca
    57181 ttgatgcagt caaaacttat gctaaacgct atgccaagtt ggctagagaa ctagcaaaaa
    57241 cggctaaacc agaacgtcaa gcagaattgt tagacatcgc gcgcatttgt gacaaagtac
    57301 cttacgaacc agcgaaaacc tttgcagagg ctgtgcaatc tgtctggttc attcagtgta
    57361 tcttgcaaat tgaatcaaat gggcattccc tatcttatgg ccgctttgac cagtacatgt
    57421 atccttatgt caaagctgat ttggaggctg gccgtgaaac agaagacaca atcgttgagc
    57481 gtttgactaa cctctggatt aagaccttga ccattaataa agtacggagc caagcccaca
    57541 ccttctcatc agcagggagt ccactttacc aaaacgtgac gatcggcggt caaacacgcg
    57601 ataaaaaaga cgcggtcaac ccattgtctt accttgtcct acggagtgtg gctcaaacca
    57661 aattgccaca acctaacttg actgttcgtt accacaaagg cctagacaat acctttatga
    57721 acgagtgtat cgaggtcatg aaacttggtt ttggtatgcc agccatgaac aacgatgaaa
    57781 tcatcattcc atctttcatc aaaaaaggtg tcttagaaga agacgcctat gactactcag
    57841 ccattggctg tgtggaaaca gcagttccag gaaaatgggg ctaccgttgc acggggatga
    57901 gttacatcaa cttccctaaa atcttgctga ttaccatgaa tgacgggatt gacccagcat
    57961 caggcaagcg ctttgcaaaa ggacacggtc acttcaaaga catgacctct tatgaagaat
    58021 taaaagcagc atgggatgct accctgcgcg aaattacccg catgagcgtc attgttgaaa
    58081 atgccattga cttaggtctt gaacgtgaag taccagatat tctttgctca gccttgacag
    58141 atgattgtat cggcagaggc aagaccttaa aagaaggcgg agctgtttac gactatatct
    58201 caggccttca agtcggtatt gccaacctat cagactccct agcagcgctg aaaaaattag
    58261 tgtttgaaga aggtcgctta accccagaag aactctggca ggcccttgaa agtgactttg
    58321 ctggagagcg cggagaagag atccgacaaa tgctcatcaa tgacgcacca aaatatggta
    58381 atgatgatga ctacgcagat agtttagttg tcgaagctta cgacacctac attgatgaaa
    58441 ttgccaaata cccaaatacc cgttatggac gtggcccaat cggaggtatc cgctattctg
    58501 ggacatcatc aatctcagcc aatgtcggac aaggaaaagg gaccttggcg acaccagacg
    58561 gtcgccatgc aggcacacca ctagcagaag gctgttcacc agaacacagc atggacaaaa
    58621 aaggacctac ttcagtattg aaatctgttg ctaaattacc aacagatgag attgtcggag
    58681 gagtactact caaccaaaaa gttaacccac aaaccctggc caaagaagaa gacaaactga
    58741 aattaatggc cttacttcgt accttcttta atcgcctaca cggttatcat atccagtaca
    58801 atgtcgtgtc acgtgaaacc ttgattgatg cccaaaaaca tcctgaaaag caccgcgacc
    58861 tcattgttcg tgttgctggc tactcagctt tcttcaatgt gctctcaaaa gcaacccaag
    58921 atgacattat tgaacgtaca gaacacacac tttaggagaa aataagtatg gaatacatgt
    58981 tagacacttt agatttagaa gctattaaaa aatggcatca cattttgcct ctcgcaggtg
    59041 tgacctcaaa cccttctatt gccaaaaaag aaggtgacat tgatttcttt gaacggattc
    59101 gagaagtccg tgctattatt ggtgacaagg cttctattca tgttcaagtg atcgcccaag
    59161 attacgaagg catcttaaaa gatgctgctg aaatccgcag gcaatgtgga gatagtgtgt
    59221 atgtcaaagt acctgtaacc acagaaggcc ttgcagccat taaaaccttg aaagccgaag
    59281 gctatcacat cacagcaacc gctatttata cgaccttcca aggactatta gccattgaag
    59341 ctggtgctga ttatttggct ccttactata accgtatgga aaatctcaat attgatccag
    59401 aagctgtcat agaacaatta gcagaagcta ttaaccgcga gaatgctgat agtaagattt
    59461 tggcagcaag ctttaaaaat gtggctcagg tcaataaatc ctttgctctg ggagcacaag
    59521 ccatcactgc tggcccagat gtgtttgaag caggatttgc catgccatct attcaaaaag
    59581 cggttgacga ttttggcaag gattgggaag ccattcatca ccgcaagagc atttaagaaa
    59641 tagcatcagt agtaatcaca tcattaggaa tcacagataa aggagttcaa cgatgaaagt
    59701 atttgcaagt ccatctcgtt acattcaagg taaaaatgcc ttgtttacca atgctaaaac
    59761 cctaaaacaa ctaggggata gccccatttt actgtgtgat gacgtggtgt atggcatcgt
    59821 cggagaaaga tttgaaagct atttgataga taatggcatg actcctgttc acgtagcctt
    59881 taatggcgaa gcctcagata atgaaatcag ccgcgtggtt gccattgcca aggaaaatgg
    59941 caatgatgtt attattggac ttggtggtgg aaaaaccatt gacagtgcta aggctatcgc
    60001 tgacttactt gctgttccgg tgattattgc cccaaccatt gcttcaacag atgccccaac
    60061 ctcagcctta tcggttattt acaccgatga aggagccttt gaaaaataca ttttctattc
    60121 aaaaaatcca gatcttgttt tggttgacac acaagtgatc tgtcaggcac caaaacgatt
    60181 actggcctct gggattgcag atgggttagc aacatgggta gaggcgcgtg ctgttatgca
    60241 aaaaaatgga gacaccatgg caggtggcaa tcaaaccttg gcaggagttg ccattgccaa
    60301 agcctgtgag cagaccttgt ttgcagatgg cctaaaagcg atggctagct gtgacagaca
    60361 agtcgtgacc ccggccttgg aaaatgtcat tgaagccaat acactcctta gtgggcttgg
    60421 ttttgaaagt gcgggtctgg ctgctgcaca tgccattcac aatggcttta cagcgctgac
    60481 aggtgctatt catcacctta cccatggtga aaaagtcgcc tatggcacgt tgacccaact
    60541 cttcttggaa aatcgttcgc gtgaagaaat tgaccgctac atcgactttt accaagctat
    60601 tggcatgcca acaaccctca aagaaatgca tttagacacg gctactcaag aggatttctt
    60661 aaaaattggc cgtcaagcaa ccatggcagg cgaaaccatc catcaaatgc catttgttat
    60721 caccccagaa gatgtagcag cggctttggt tgctgttgat gcctatgtta cgagtcgata
    60781 ggctaaccaa aaagagattt cttatttgcc agataacctc aaaaaaacaa gtctagggag
    60841 tcacttccta gacttgtttt gcttattgtt ggttggtaat agcactttta gcggggtcat
    60901 tgtgggcaat acggctggca gctgcagcag caatggcgct aacaatatca tctaaaaagg
    60961 tatggcagga tttgccatct ttatggttga gtttgtcaac aattcctggt tttgtcttgt
    61021 ccagataccc ataattggta aaaccgatag acccatagag gttaacaatg gataaggcca
    61081 ggatttcatc aatcccatac agcccttggt cggttttcaa gatactaagg agtggctcag
    61141 acagctggtt ggcttcagcc aatttatcca attctacccc agtgataata gtattttgca
    61201 cttctcgttt tgcaagcacc gcctcaacgc tctctaaaca ttctgccatg gtcaaattgg
    61261 gaatataatc attctgcaaa aaaagcacca gctctgcaat agcttctaaa gaaacccctc
    61321 gctcagccag taattgataa gacacttctc gtaattgatg gtcagttgac atgtgagacc
    61381 tccttttttt ctttattgta acataaaaga tttcgagaaa cctctacaac agctaaagag
    61441 gggatagttc ttttttaaga gatgttgact actgagatcc cctacttggt aaaagtcaaa
    61501 gaaacgatag taaagtaacc atcttaccta ggcctaaata caatcaccac ccctaggtga
    61561 cacacagcac ctatttcaaa aatgatatta gtatggcaaa acaaaaagac aacgccttct
    61621 tttttctcct tactatctcc tttaattttc atatttttta aaaaaactat tgataaacta
    61681 gttaagtaag cgtatactat ggttagtgag cgaaattaga aaagaggaca agcatatgaa
    61741 tctacttgga tcaagacggg ttttttctaa aaaatgtcgg ctagtgaaat tttcaatggt
    61801 agctcttgta tcagccacaa tggctgtaac aacagtcaca cttgaaaata ctgcactggc
    61861 acgacaaaca caggtctcaa atgatgttgt tctaaatgat ggcgcaagca agtacctaaa
    61921 cgaagcatta gcttggacat tcaatgacag tcccaactat tacaaaacct taggtactag
    61981 tcagattact ccagcactct ttcctaaagc aggagatatt ctctatagca aattagatga
    62041 gttaggaagg acgcgtactg ctagaggtac attgacttat gccaatgttg aaggtagcta
    62101 cggtgttaga caatctttcg gtaaaaatca aaaccccgca ggctggactg gaaaccctaa
    62161 tcatgtcaaa tataaaattg aatggttaaa tggtctgtct tatgtcggag atttctggaa
    62221 tagaagtcat ctcattgcag atagtctcgg tggagatgca ctcagagtca atgccgttac
    62281 agggacacgt acccaaaatg taggaggtcg tgaccaaaaa ggcggcatgc gctataccga
    62341 acaaagagct caagaatggt tagaagcaaa tcgtgatggc tatctttatt atgaagctgc
    62401 tccaatctat aacgcagacg agttgattcc aagagctgtc gtggtatcaa tgcaatcttc
    62461 tgataatacc atcaacgaga aagtattagt ttacaacaca gctaatggct acaccattaa
    62521 ttaccataac ggtacaccta ctcaaaaata ataccaaaag gctagacctc tgctcactag
    62581 gcctagcttt ttacatcaaa aaaagcaatg acttatagaa agtaaaaata ctagaaaaag
    62641 caatgattgc cgtcattgct ttttatgatt tgtcaaaaag taaaaagcaa attgaaaaaa
    62701 tcgccctgga gctgttgaga taaactacac catttattaa gataccaaat caaaaagcta
    62761 acaccataag agcgttagct ttttaaagag cctcaggaca gtttatgttt aatggcttct
    62821 aggtaggttt gaaacatatg atggatcgtt ttgcaattaa gtaattggaa gatctccaag
    62881 atctgcacac acttttgctc agccccctct ttaccattta tgaggccaat aatgccatca
    62941 aaaaaagaca cacaacaccg ttcatataag caatcatcat ttagctgata atcttcaatt
    63001 tttgccaaaa tctcagaagc tttatcatac tcttgtcgct gaataaacaa aatcaacata
    63061 ttgacaaaca tccgaatcga ttcattccca taatacctta gggtattgta tttatcgagg
    63121 ttcaaaataa cttttgaaaa caccatctca ataaagcaag actcaaaaat aaacatacaa
    63181 ttattaaaaa gcacagtctc atagtgactc caagtttcaa tattaataag atagtttgac
    63241 aaataagtcc gctctgtcag acagtcttcc tcagtaagag ttgctaataa caccttgacc
    63301 aaggcaaaaa ggttcttttc ctttgttgac ttactatctt tataagaatc aaggatatga
    63361 tttaaacctt ctatgtttcg gcattcaaaa taatgttttg ccgtatccat atcaataaat
    63421 tctttatatt gtttaaagtt attactaata aagagaaact catcaacatt gacattcaag
    63481 ttgtctaaga tataaagtaa ctttttcgaa gaaatgtcaa gattattttt aataaaacga
    63541 taataggttt gcctagtgag ataatcacca caaacttgtt taatcgaaat gttttttgaa
    63601 tgcctaatga attcaacggt ttcaccaatt tccatatgtc aagccttcct agttgatgtc
    63661 aaaaatacgt tacgcatgta cctaatacgt aacaagttga atgtttcgga tgatagtcgc
    63721 ttatgatagg tgcataaggt caatagccag atgcgatagt tttatcaact gtcatatgtt
    63781 aaacctttct aatctaatag atgttaaaaa tacgttacgt gtgtacctaa tacgtaacaa
    63841 aataatgggt tagcaaaata agcagctatg atatagccat aaggttaaaa ggaggcgcct
    63901 actatgtggt tattgttact atttttgtag ttccttttgc aaaatggtag tagataaaaa
    63961 tgagaagtca ataaaagcat tgacaaacaa aagaatcatt ttgtttatat tatcagtatt
    64021 tttaagtttc ttgtcaactg aaatgagcat ctactagcca caatagtaac taaaaggcta
    64081 attgtcagta aaaatgagat aaatcagcca ggaaaaagcc tacgagtcaa ctaatggaca
    64141 acccaaaaaa agacaaagga ctttcacttg gtgttgtgga ccctatcacg atccttatca
    64201 cagaatcagt tattaacaaa atgagaacgg tcccatatca tctaaaaaaa ctgtcaagca
    64261 caacctattg tttgctagct gatcttgcct atcagtctgc ctagtagata cggcagaaga
    64321 taagagatca accaaaagat gataagtgca acgactcata gcgtcttttg accaaaacca
    64381 attagactca catgagatga gaataattgg gttgggttgt cagtgtcgac taaccgtgtt
    64441 attgtctatt accattcatg gtatcagcga catcgtatga taaccatgcg attcagctaa
    64501 gtaaggaggt gtgtccaatg taccgttaaa agcaaatgca gtagattaac ttattttgaa
    64561 agaggtataa aaaaaatgaa taaaaagaaa ttaggtatca gattattaag tcttttagca
    64621 ttaggtggat ttgttcttgc taacccagta tttgccgatc aaaactttgc tcgtaacgaa
    64681 aaagaagcaa aagatagcgc tatcacattt atccaaaaat cagcagctat caaagcaggt
    64741 gcacgaagcg cagaagatat taagcttgac aaagttaact taggtggaga actttctggc
    64801 tctaatatgt atgtttacaa tatttctact ggaggatttg ttatcgtttc aggagataaa
    64861 cgttctccag aaattctagg atactctacc agcggatcat ttgacgttaa cggtaaagaa
    64921 aacattgctt ccttcatgga aagttatgtc gaacaaatca aagaaaataa aaaattagac
    64981 actacttatg ctggtaccgc tgagattaaa caaccagttg ttaaatctct ccttgattca
    65041 aaaggcattc attacaatca aggtaaccct tacaacctat tgacacctgt tattgaaaaa
    65101 gtaaaaccag gtgaacaatc ttttgtaggt caacatgcag ctacaggatg tgttgctact
    65161 gcaactgctc aaattatgaa atatcataat taccctaaca aagggttgaa agactacact
    65221 tacacactaa gctcaaataa cccatatttc aaccatccta agaacttgtt tgcagctatc
    65281 tctactagac aatacaactg gaacaacatc ctacctactt atagcggaag agaatctaac
    65341 gttcaaaaaa tggcgatttc agaattgatg gctgatgttg gtatttcagt agacatggat
    65401 tatggtccat ctagtggttc tgcaggtagc tctcgtgttc aaagagcctt gaaagaaaac
    65461 tttggctaca accaatctgt tcaccaaatc aaccgtagtg actttagcaa acaagattgg
    65521 gaatcacaaa ttgacaaaga attatctcaa aaccaaccag tatactacca aggtgtcggt
    65581 aaagtaggcg gacatgcctt tgttatcgat ggtgctgacg gacgtaactt ctaccatgtt
    65641 aactggggtt ggggtggagt ctctgacggc ttcttccgtc ttgacgcact aaacccttca
    65701 gctcttggta ctggtggcgg cgcaggcggc ttcaacggtt accaaagtgc tgttgtaggc
    65761 atcaaacctt agtatggaaa tgcatttcgt tagaacagaa cctgaggcac gccgcatagc
    65821 tgaaaccttt tgtgccgaaa acacacaaac aaaaacccct atgcgcgtgc agcagttaag
    65881 ctatccatca gacacagatc actcaagtgg tgagctatac atctatgctt tgtctcctgc
    65941 tggatttatc atcgtatcag gagacaccag agcgcacacc attttaggct attcttttga
    66001 taataaccta gacctcaacc atgataatgt caggagtatg atagaagctt accaaaaaca
    66061 aatcagctct ttggattgat cggtcaaagg agcttttgcc cccctcacca ctcgtttaag
    66121 acgaccgtgt ttctaaaata ccactacctt ttaagtttca cgccggccta agcgagtgtt
    66181 tgtctcatgg agcagactgt ttccatcgaa aagtcaccca ttgataaagg aggtcatcaa
    66241 cgcctactaa tgatgacttc cctaagatgc caaggtaaag gactgagttc tgtagagatg
    66301 ggactcagtc cttttacgat ttttgggagt tattctagcc ataccgtggc aagaaaacaa
    66361 cacttaaaaa tagccaacgt cagtttttgt tcatacatga ctacagccaa acaccacaac
    66421 ctaacctatc ctaaacacaa tggctttcta acgaacagtc acaacgagca gcaacaccaa
    66481 aaagcaagat taagctacgt ttaagactaa tgatataaga taacagtaat tattaatgag
    66541 aaaagaggct caggacatga aacaaatgaa taaactcatt acaggagtgg taacgatggc
    66601 gacagtcgtg accttatcag cttgtcaatc atcacacaac aacaccaaac tcgtctcgat
    66661 gaaaggagac accatcactg tcagtgactt ctacaatgag accaaaaaca cagaactcgc
    66721 acaaaaagcc atgttaagct tggtgattag ccgtgtattt gagacacaat atgccaacaa
    66781 agtctctgac aaagaggttg aaaaagccta taaacaaact gcagaccaat acggtacatc
    66841 ctttaagaca gtcctagcac aatcaggctt aacgccagaa acctataaaa aacaaattcg
    66901 cctcacaaaa ttagttgaat atgccgtcaa agaacaagcc aaaaacgaaa ccatctcaaa
    66961 aaaagactac cgtcaggcct atgacgctta taccccaacc atgaccgcag aaatcatgca
    67021 gtttgaaaaa gaagaggatg ccaaagcagc ccttgaagcc gtcaaagctg aaggggcaga
    67081 ctttgcagct attgccaaag aaaaaaccat tgcagccgat aaaaaaacaa cctacacgtt
    67141 tgactcaggc gaaacaaccc taccagcaga agtagttaga gctgcatcag gcctcaaaga
    67201 agggaacaga tcagaaatca tcacagcgct tgatccagcc acctcaaaac gcacctacca
    67261 tatcatcaaa gtcaccaaaa aagcaactaa aaaagcagac tggaaagcgt accaaaaacg
    67321 cttgaaagac atcatcgtga ctggcaaatt aaaagaccct gacttccaaa acaaagtcat
    67381 cgctaaagct cttgataaag caaatgtcaa aatcaaagac aaagcatttg ccaatatctt
    67441 agcccagttt gccaaaccta accaaaaaca acctgcccaa aaatagaagg ttgccagttt
    67501 atttccctaa ggttgcttaa aaagacagcc ctagccatca ctcccctttt caaaacaccg
    67561 ataatggaaa cgtgtcctat actgatggtc tagggcaatg tcataaagct aaagactcta
    67621 tccaaataag gatagagtct ttaatgttta aaaaccagtc agtaaaaaaa ttcacgctaa
    67681 gcctcattct aggcttagcg tgaatggtat cagtgatagt ccgttaacat agctgattgg
    67741 gagtcagaaa ctctaactac ccaatctgac tataccccca gtaccagagg tgtctcatcg
    67801 cagaagtagc aatcagataa tcgtctgata agctcttgtc ctcaagcaac tgatgagtct
    67861 cgtcgcacgg gccatgagct gttggtggct gatagctagt aggttcatca gccaaaactt
    67921 ttttggagta acgctttggt ctcagacggc gccagagggt tgagagaggg gtgagaaaaa
    67981 aacgatgggt catcttggcc tccttgtcta acgatagtca ccttaacaga caaaagtgtc
    68041 aataatttca ttttaaggag aaaaagatta aaaatcaagg tcacaaactt tactttgtta
    68101 aaaaaacgcg accctaataa agaacttaaa tacccctcgc acttgagctt ctccttgcgc
    68161 agttatcttg cgcactcagt tgcctccaag ttagtgacag cgataccatc attgtccttt
    68221 aagctatcgc gacagatcct tttttcgcct cgatgaggct gacacagctg tcatgacaga
    68281 gaaaatgcct ctgattatct aagagaccat taattttcct ctcaccaaaa aactgatttt
    68341 ataaaagaaa aaacatggtg tataataagg ttcgaaacaa ttatgacata ataatgaaag
    68401 taaggttaac gaaacattga caaattgtaa gtataaactt agaaagttat ctgtagggct
    68461 cgtctccgtc ggaacgatgc tgatagcccc gacagtttta ggacaggagg ttactgctaa
    68521 tactgagacg agtactactc cagccaccac tactcctagt gctggtaccg gtacggctac
    68581 gacaagtggg acagctacca ctactcccag tgctactaca gatgctggtg gagaagctgg
    68641 gagtggaact aatggtgcgt cttccgtaac atctagtgga ggaagtcaga gttcaggcac
    68701 tactccagcc tcaccccaac ctcaagcaca gacaactcca gcagcaacgt cgatatcatc
    68761 gaactcttct agtgatgggc aaattcccaa gacagcaatt acatcacctt caaccccagt
    68821 agcagccagt aataatagca atcaagaagc tagtgctgag actgagccac agacgatgga
    68881 agtggaaaag tatacagttg ataaggaaaa ttcaaagcta aatattaaag acggtgataa
    68941 gccaaaaaat gggagtagtg tcgatgataa agacacaaaa cttattagaa accgcgatgg
    69001 caaacagcgt gatattgttg atgttactcg gacagttaaa actaacgaag atggcactat
    69061 tgatgttacc gtaacggtta aaccgaagca aattgacgaa ggtgctgatg ttatggccct
    69121 tttagatgtc tctaaaaaga tgacagaaga ggattttaac aacgctaagg aaaaaatcaa
    69181 gaaactagtc acaaccttaa ctggaactgg gaaaaatggg ggagaacaca aagctcgcaa
    69241 ctctgtgcgc ctaatgacct tttaccgtga gattagcaaa ccgattgata tatcaggaaa
    69301 aactgaggaa caacttgata cgctattaaa taagcttcgt caagaggcta aggatgagta
    69361 tgattggggg gttgatttac aaggcgctat ccataaggct cgagacattt ttaataagga
    69421 aaaggaaaaa gagtcaaaaa aacgccagca tatcgtcttg ttctctcaag gcgagtcaac
    69481 ctttagttat gatattaaaa ataaagatga taaaaaatta caaaaaactc atttaaccac
    69541 tgtgacgacc tctaatccat tattttcttg gtttcctatc tttgaccaca caaatcgaaa
    69601 agcggatatg attgatgata ttaagtatct tattaagtgg ggtgaagcat taggaataga
    69661 aggattaagc ggactgaaag acaaattaag tttagcaggt ttagctagta gcgccctggg
    69721 tggtttgttt agtggaggta gtctaacgga gtatcttagc cttaaagaat accagtcaga
    69781 tagtcttaaa gctgatcaat ttaactatga aaaacgagtt ggagaaggtt attattatca
    69841 tagcttttct aaaagagaga cagcagatat gccgaacaga gatttgatta agcagaattt
    69901 agaaggtctg tttaaggaaa aagacggtaa ttggtttaag tctattttag acaagctatc
    69961 acttacagat aaatatcaaa aagcaaaaga agcagcgctt ttgaaagtgc ttgactacct
    70021 cttttacaaa cgtgaatacc actactacaa tcacaacctt tcagccattg ctgaagctaa
    70081 aatggctcaa caagaaggca tcaccttcta ctccgttgat gttactgatt taaacaccgc
    70141 tagaagagtg aagcgacaaa cagcaacata tacggatgac aagaaaaaag aaattgaaaa
    70201 aattgaagaa gagcgtaata aaaagtttga tgcctatctg agaaagatgt ctgaagataa
    70261 tgatttctta agtgatgttg aagataaaga taagttcaaa gatactttaa ctgacgtaac
    70321 ggtgactgag acttttgaag atggagttaa cgttaaagaa aatttatatc agacttcatt
    70381 ggatagcaat agtaatggct caaatagtaa ttctggggga gatgttagac atacaaaacc
    70441 atctggatca agttggtgga cctttagtgg taccaaagaa agccttactt ggaccatttc
    70501 caaagaccag ctcaaagaag cctttgagaa aaatggtttt ctcactttta aatacaaatt
    70561 acaggtcaat aaagacaaac tacttaaaga cattaagaga acaaaacgtg gtacatctac
    70621 ggaaaataag acttctgtaa cgaaagacat tatttcaaat actattacct acaaaattaa
    70681 tgaacaaaaa gttaaaggta ataagcttga aaatgtcaag ttgacttata ctaaagagac
    70741 cgttcctgtt ccagatgtgg aaggagaagt tgtaccaata ccagaaaaac cactggtaga
    70801 accaatgacg cctctatacc ctgcaattcc taattaccct acccctcaac ttccaaaaga
    70861 tgaagatctg gagattagtg gaggtcatgg accgattgtc gatatcgtcg aagatactgg
    70921 tacaggtgtt gagggtggcg ctcaaaacgg cgtggtttca actcaggaaa ataaagatcc
    70981 aatcgttgac atcaccgaag atacccaacc aggtatgtca ggctcaaatg acgcgacagt
    71041 tgtcgaggaa gccacaacac ctcaacgtcc agatatcctt gttggtggtc aaagtgatcc
    71101 aatcgatatc accgaagata cccaaccaag tgtgtcaggc tcaaatgacg ctacagttgt
    71161 cgaggaagcc acagcacctc aacgtccaga tatccttgtt ggcggtcaaa gtgatccaat
    71221 cgatatcacc gaagatactc aaccaggtat gtcaggcgca aatgacgcta ctgttatcga
    71281 agaagatacg aaatcaaaac gcttcttcca ctttgataac gagccacaag caccagaaaa
    71341 acctaaagag caaccatctc tacaagatag taacagctta ccacaagctc cagcctataa
    71401 ggcagctcat cacttgcctg catctggaga caaacgtgaa gtatacttta caattgctgc
    71461 tctaacaatt attggagctg caggtttgct cagcaaaaaa cgtcgcgaca ccgaagaaaa
    71521 ctaaccctcg ttagtctagc gaccctaagc ctttggcttt aaaaatttct cattatcccc
    71581 ctcaaacatc ggtacctcac tgagatggcg cttaaaaaag gcgctagtct caaatcaggt
    71641 atcccctacg gttgaggggg attaatgggt atcacatcaa gaaaaaaggt ataatgatga
    71701 aatatgacta aaaaatttat taaatcagca gtgattctag gcttagcaag cataaccatc
    71761 agcatgacgc aacccgttga agccatttca aatagcttag aatatcaagc acaatataaa
    71821 cgtgtcaaag aagaactaga cgcattaaaa gaaaatagct caaaattagg agaacgttcc
    71881 ctttatttta gattggtgaa tagatttcta ggttggtttg gccaagtctg ggacccactc
    71941 gcaatcaaag aaaccgatta cctgttggac ctcatcggac aagtcaatta cttggtgagt
    72001 aacaccgagt ttcaagcccc tgagtacaaa gatgctaaaa acaaactaga cttagctgta
    72061 gcaggctatg agctctacct agctagagaa aaagaacgtg gtgatgctcc tgattaccaa
    72121 gtgacccagc taacgttcaa acagctcgaa accattaaaa cgaagatacg agaggcccta
    72181 gaaacatttg cacaagaggt caaaacaatc caacaaaaaa acccagacct atttccccat
    72241 gcttatgttt taaacactaa gagcaaagat atcacagata aagcgcaacc ctttttagtg
    72301 aatggttact acgatgtctt ttataagcag tttttattca ctaatacaaa ggacgggtat
    72361 aactataata aagaagcaga taacctgacc tcgtatcaag atctgattaa agaactatta
    72421 gacttaaaag ctgagatcga tcagttaaca aaaggcaaga ctggagatga ccgtttagag
    72481 atgttaatgt ggcaatcaaa gttgacctta tctgattcac ggagaacttc acgccttagc
    72541 gcctactatg cacaaggtga ttatatcaat aaggtggtcc tatctgaaga agctcccaac
    72601 ttgagaacag caaaagaaaa ggtcaagacc ttaaaaggga tcttgtatga ttactatgtt
    72661 gaaactaatg agccagaaaa agctaaacag tatcgtgtcg aggacgagac cttgccgtct
    72721 caacctgagg cccctgctaa acctgcagct cctgctaaac ctgcagctcc tagtcctggt
    72781 caaaaaccaa cagaagatga gggatcgtca caagcaacgg agccagctaa cccgtcaaaa
    72841 gaggattcct caacggacgc atctcaggga tctcacgata gcgaaaaccc agcgacggat
    72901 aatccttctc aacctcaggt accagaccaa gacaatcacc aaagccaagt gcctaacgaa
    72961 aagcctcaaa cggacaagac ggacactcct aacgtcccag cccctccaca ggacacccca
    73021 aaagtgcctg aggctggtgg tcagagtggc cccgctggga acgctgagga gaaagctcct
    73081 gactctggac ctaaagagtc tgatcaaagc tcatctaaag agtccccatc cgttggcgaa
    73141 gacacgaccc ctaatcagcc agacgtcctt gtaggtggtc aaagtgagcc aattgatatc
    73201 acagaagaca caattactga cgctccaccg acagtatctg ggcacaacgc atcaacacag
    73261 ccccaatctg tggtcgaaga cacagcacct cagcgcccag atgtccttgt aggcggtcaa
    73321 agtgatccaa tcgatatcac ccaagatacc caaccgggca tgtcaggctc taatgacgct
    73381 accgttatca atgaagatac aaaaccaaaa cgcgtcttcc actttgataa caaagagcca
    73441 caagcatcag aaaaagcggc agagcaaaaa cttgctcctc atgataacca cacaacccct
    73501 caaacttcag atgatacagc agcccctcac ttgcctgcat ctggagacaa gcctgaaaaa
    73561 gtgtttgcac ttgctgcctt gacaatggtc gcagctgcag ggctactcag caaaaaacgt
    73621 cgcaacaccg acaaaaacta gtcgctgtta gacacaacgc atcactaagg ccagtgcaaa
    73681 tgcactggcc ttagttaggt ttttatcaaa tagagggttt ttcatgacaa ttgttagcgt
    73741 ttcggtgtaa aataaaggta ataaccagca aaggagcaac ccatgacaaa gcaagatcag
    73801 ttaatcgttg aaaaaatgga acaaacctat gaggccttta acccaaagct agcaaatctc
    73861 atagaagccc tagatgcctt taaagagcat tatgaggaat atgccacact tagaaatttt
    73921 tacagtagtg acgaatggtt tcggcttgca aaccaacctt gggatgatat cccgtgcggt
    73981 gtcctatctg aagacctcct ctttgatatg atcggtgacc ataaccaact actagctgat
    74041 atcttagact tggcccctat catgtacaag catatgtaac catcgctaac gtcacagata
    74101 ccacgatgac aggacaaaaa aagcttgaaa atctcaaaaa aacagataaa aaacagataa
    74161 tcgttagaaa aacagtagat gcgtctgtta aactaaaggt atcaaaacaa aaggagcatt
    74221 tcatcatgaa attcaaaaaa gtattagtca ttcctgcatt agcattagca gcaacatgct
    74281 ttttaacagc ttgtggcaca aaaaaagatt ctaaaaaaga agaagttaaa gaaatcaaaa
    74341 tgtctgacat caaagacgac gcagttagca aaaaaacaaa agtggttgat ggcgaagaag
    74401 ttacagaata caccacaaaa gatggaaacg tgattcagat tcctgcagga aacgaagaag
    74461 gcatggaatc aaaagatgct ggtggatcag gcgctcctgc taaaaactaa gggttacaac
    74521 aaagagcata aggtgactcg caaacgttac gcatgacatg aggcagtctg cctaagatgg
    74581 taactcactt atcataatgc ctaaatagcc aaacacacta actcgcaaat gtacaaaatc
    74641 atatacccgt gcttatgtga gcgaacggtt atatgatttt tgttttccaa aaacaagaaa
    74701 agaacgctaa aatagccagt ttgtcgtgtt tcaagctacg aaaaaggaag tgctaaaatg
    74761 aaaaaaagat ccattatacc tgtcatctta ctgttggtca tcggattaat cgttggtgtt
    74821 aagcgtcatc atgactagta ggtcttgcta gtgaccgttc aaaagggata acgttggtat
    74881 ggtataacca taaaaatcgt ataaaaagaa aaaatagcta ttgaggagaa agtatgtttc
    74941 agttaagaaa aaaaatgacg cgcaaacaat tagccttgtt gagtgctgga gtgttgacct
    75001 gtgtggttgg tggtagctac ttgataatga accatcaaca acaagaaatt gtctctagtg
    75061 tcaacaaagt aaaagcctta accataaaag aagccatgga acaaggaaaa gatatcagct
    75121 tgaccttagc tggcgaagta acagctaaca acagcagcaa agtcaaaatc gactcaagta
    75181 aaggagaagt caaagatgtc tttgttaaaa aaggcgatgt tgtcaaagta ggacaacctt
    75241 tgtttagcta tgaaacgtca cagcggttaa cggctcaaag ttcagaattt gatgttcaaa
    75301 ccaaagccaa tcaactccaa gttgctaaaa ccaatgcagc attgaagtgg gaaacctaca
    75361 atcgcaaggt caatgaaatc aacaccctaa aatctcgcta caacactgca ccagatgaga
    75421 gcttactaga gcaaattcgc agcgcagaag acagtgtatc ccaagcacta agcgatgcca
    75481 aaacagcaga tagcgatgtc aaaaccgctc aaatcgaact cgataaagct aatgctactg
    75541 ccacaacgga aaaaggtaaa ctagagtatg acaccgttaa gtcagacacc gcaggaacca
    75601 ttgttagcct aaatactgat ttgccaaatc aatcaaaatc caaaaaagaa aatgaaactt
    75661 ttatggaaat tatcgacaaa tcaaaaatgt tagtcaaagg taacatcagt gaatttgacc
    75721 gtgacaagtt aaaaatcggt caaaaagtcg aagtgattga ccgcaaagac aactctaaaa
    75781 aatggactgg aaaagtaacc caagttggca acctcaaagc agaggaaaaa ggccaaggtc
    75841 aaggccaagg tggcaatgac caacaagaca atccaaacca agcaaaattc ccttatgtta
    75901 tcgaacttga ccaatcagac aagcagccac tcattggctc acacacctat gttaatgtgc
    75961 tcaacaatgt tccagaagct ggcaagatcg tattgaaaga aacctttaca atggcagaaa
    76021 atggaaaaac ctatgtgtgg aaagttgata aaaacaaggt caaaaaacaa gaaatcaaga
    76081 ctaagccctt ctcaaaaggt tatgttgagg tgacaagtgg cttgaccatg caagataaga
    76141 ttgctcagcc gcttcctggc atgaaagacg gtatggaggt aggaagtatt gttaaacctt
    76201 aaagatattc gaaaaagcta tcatcttggg actgaagaat ttgcgatttt aaaaggaatc
    76261 gatttagaag ttaacgaggg tgacttttta gccatcatgg gaccatcagg ttcgggaaag
    76321 tcaacattga tgaatatcat tgggtgttta gataagcctg gctctggctc atatgccatt
    76381 gaaggcagag acgtgtcatc cttatctgat aatgaacttg ctgatttgcg taatcaaaaa
    76441 atcggctttg tttttcaaaa ctttaacctg atgcccaagc taacagcttg tcaaaatgtc
    76501 gaattaccct tgacttatat gaatgttcct aaaaaagagc gtcgcaaacg agccctagag
    76561 atgttaaagc tagtaggact agaagaacgt agtgaattta aaccgatgga gctatctggt
    76621 gggcaaaaac agcgtgtagc gattgcaaga gctttagtca ctaacccgag ttttatcctt
    76681 ggtgatgagc caacaggtgc actagacaca aaaaccagcg tccaaatcat ggacctattt
    76741 aaacaattca atgataacgg caaaacgatt attatcatca cacacgagcc tgaagtagct
    76801 gccttatgca aaaagacggt gatcctaaga gatggtaata tagaacattc cgatatagag
    76861 taaaggggga aaataatgga agatattatt gcagctttaa gctctatatt atcacacaag
    76921 atgcggtcaa ttttgacaat gctagggatt attatcggta ttggtgccat tatcgcaatc
    76981 ttttcaatca tcgaaggtaa taccgaaaat accaaaagac agttgattgg tggcagcaat
    77041 aacactatta acattgtgtt taacaaaaaa agtagtattg accctaaatt tccagacaag
    77101 tcaaatgcta aaaaaccaga ctatcttcct tttatggctg aagaagagct tagcaaaata
    77161 cagcaagtca aaggcgtcaa aaacgccctg atctcatatg gtattgatga caaagtctac
    77221 catctaggcc aaaaatcatc tgcaaagatt tctgccatca caaaaaacgt agctgaagtg
    77281 agacgcatga catttattaa aggcagtgac ttttcagaca aagactttat tgaccaaaaa
    77341 caggtgattt accttgaaaa aagcttgtat gagtcactat ttccaaaaga cgatggtctt
    77401 ggaaaatttg tcgaagtgat gggaaatccc ttcagggtca ttggggtgtt tgaatcaaaa
    77461 gaacaaagtg gcctcacaag tgggactgag aaaattgctt atatcccgct acatcagtgg
    77521 tataatatta atggtgtagt ggatgcgaca cctgagatca cgatccagac ctatcgcgca
    77581 gatgacctca aacctgtagc aaagcgtgtc agtgatatgc tcaatcaaac gatccctaaa
    77641 tcagattata tgtttggtgt catgaacctt aaagaatttg aacgccaact agacaaccta
    77701 aacaaatcta attttgtgtt attagctggt attgctagca tctctcttat tgtaggtggt
    77761 attggtgtga tgaacattat gctagtatca gttaccgaaa gaacgagaga aattgggatc
    77821 aaaaaagcgc ttggcgctag acgtaagctt attttaaaac aatttttaat tgaagcggtc
    77881 attctaacct tgctaggtgg tgtgataggg gttatttcag ggatggtatc aggattgatc
    77941 atcacaagat cacttgagta tccctatatc ctatccttgt tctcagttgt cttaagttta
    78001 gcgttttgtt gtattatagg gattgtcttt ggactattac cagccattaa agcgtctaag
    78061 ctagacccaa ttgaagcatt gcgatttgaa taatcaacca aacaagcata aaagtcaaaa
    78121 aggatgaccc tttgatgtca tccttagctg cttgatacac taaacgccaa tctagaaagg
    78181 gaagttatgt ttaaaatatt agtagttgaa gatgatgata ccatcagtca agtgatttgt
    78241 gagtttttaa aagcgaataa ctatgatcca gattgtgtat ttgatggcca agctgcctta
    78301 gacaagtggc agacaacgtc ttatgatctg attattttag acatcatgct cccttcctta
    78361 agtggcttag aagtgctaaa aacaattcga aagacatcag atgtccctat tattatgcta
    78421 acggcattag atgacgagta cacacagctt gtaagcttca accatttgat tagtgattat
    78481 gtgaccaaac cattttcacc actcatttta atcaaacgta tcgaaaatgt attacgcgtc
    78541 tctactccag atgaaaagcg ccaaatcgga gacttacttg ttgatgagac cgaacatagc
    78601 gtctattggc aaggaacatt ggtcaaacta accaaaaaag aatatgacat tattgattat
    78661 ttagcaaaac gtcaccaaaa aattgtcacc agagaccaat tgatggatga catatggggc
    78721 tattctgaac tggacacgcg tgtccttgac aaccacatca agaaccttcg taaaaaaatg
    78781 acgggtattc ccctcaagac aattacaggc atgggctatt tattgggaga gcgtgagtga
    78841 gactaatcaa aaaaaccttt ttggtcatca atggcttaat tattgtagtg gttacctcta
    78901 ttttgttagt gctttatttt gcaatgccaa tttattacac caaagtcaaa gacaaagaag
    78961 ttaagcgtga atttgaccaa acaagcaagc aaatcaaagg caaaacggta accgagatta
    79021 gagatatcct aacaaaaaaa atcaacaaag ataatatttg gtacagctta gtagacagtg
    79081 ataaccaact gctctatcct tccttgcagc tgttagacgg cgtcagtgaa agcaaagaca
    79141 gtcaaaatgt taatatcgtc accacctttg acaactctta ttctaatgtt aaggtgatga
    79201 gtcaaaaagt aaccctacgc gatggaaaaa agatgacatt gcttgggcaa tcttcacttc
    79261 aacccgtaac agatgctagc aaagttctcc ttgacctcta cccgtcacta ttgatttttt
    79321 cagtgaccgt agggagtatt gtcgcctact tatatagtag gacttctagc cggcgtatcc
    79381 ttagcatgtc acaaaccgcc aaaaaaatgg tcaacctaga gccaaactta acgtgtacca
    79441 ttcacggcaa agatgaaata gcaatgttgg ctagtgatat taaccgtttg tatgcgagtc
    79501 tttcaacgag catcaaatcc ttgcaaaaag agtatgaaaa agcttctgat tcagaaagag
    79561 agaaatctga gtttttacgc atgacatcgc acgagctaaa gacaccaatc accagtgtta
    79621 tcggaatgat tgatggaatg ctctataatg ttggtgactt tgcagatcgt gacaaatatt
    79681 tgcgaaaatg ccgagacgtc cttgaagggc aagcccaact ggttcaatcc attttatctt
    79741 tatctaagat tgaaacccta gcttctcaaa atcaagaact gttttcacta aaaagcagcc
    79801 tagaagaaga aatggaagtc tttctcgttt tatcagaact aaaacacctc aaagtgacta
    79861 tcaatctcga agaacaattc gtcaaagcca ataaagtata cctactaaag gcgattaaaa
    79921 atattattga caatgccttt cactatacca aatcaggcgg ccaagtgatg attcaactaa
    79981 aagacaacca actagtgatt aaaaatgaag cagagacatt attgacacaa cagcagatga
    80041 aacagttatt ccaaccgttt tatcgaccag attatagtcg taacaggaaa gacggtggta
    80101 caggattggg gctgtttatc acccaccaga ttcttgatca gcatcatctg gcttatagct
    80161 ttgttgttct tgaccaaaga tggatggtat ttacgattga ttttccatcc catcatgacg
    80221 attgatccac actagtagga cgacaaaagt catcaatcac taaccaagcc ttgaccttta
    80281 cccatcattg tttaggcaag tataaaaaag aggagagaaa tcatatatga agaaaaggaa
    80341 attgttagca gtaacactat taagtaccat actcttaaac agtgcagtgc cattagttgt
    80401 tgctgacacc tccttgcgta atagcacatc atccactgat cagcctacta cagcagatac
    80461 tgatacggat gacgagagtg aaacaccaaa aaaagacaaa aaaagcaagg aaacagcgtc
    80521 gcagcacgac acccaaaaag accataagtc atcacacact cacccaaccc ccccttcaaa
    80581 tgatactaag cagaccgatc aggcatcatc tgaagctact gacaaaccaa ataaagacaa
    80641 aaataacacc aatcaaccag acagtagtga tcagtccacc ccatctccca aagaccagtc
    80701 gtctcaaaaa gagtcacaaa acaaagacgg ccgatctacc ccatcacctg atcagccaaa
    80761 agatcagaca cctgataaaa caccagaaaa atcaccagaa aaagcaactg aaaaaacccc
    80821 agagccaaat cgtgacgctc caaaacccat ccaacctcct ttagcagcag cagctcctgt
    80881 ctttgcacct tggagagaaa gtgacaaaga cctgagcaag ctaaaaccaa gcagtcgctc
    80941 atcagcggct tacgtgagac actggacagg tgactctgcc tacactcaca acctgttgtc
    81001 acgccgttat gggattactg ctgaacagct agatggtttt ttgaacagcc taggtattca
    81061 ctatgataaa gaacgcttaa acggaaagcg tttattagaa tgggaaaaac taacaggact
    81121 agacgttcga gctatcgtag ctattgcaat ggcagaaagc tcactaggta ctcagggagt
    81181 tgctaaagaa aaaggagcca atatgtttgg ttatggtgcc tttgacttca acccaaacaa
    81241 tgccaaaaaa tacagcgatg aggttgctat tcgtcacatg gtagaagaca ccatcattgc
    81301 caacaaaaac caaacctttg aaagacaaga cctcaaagca aaaaaatggt cactaggcca
    81361 gttggatacc ttgattgatg gtggggttta ctttacagat acaagtggca gtgggcaaag
    81421 acgagcagat atcatgacca aactagacca atggatagat gatcatggaa gcacacctga
    81481 gattccagaa catctcaaga taacttccgg gacacaattt agcgaagtgc ccgtaggtta
    81541 taaaagaagt cagccacaaa acgttttgac ctacaagtca gagacctaca gctttggcca
    81601 atgcacttgg tacgcctata atcgtgtcaa agagttaggt tatcaagtcg ataggtacat
    81661 gggtaacggt ggcgactggc agcgcaagcc aggttttgtg accacccata aacctaaagt
    81721 gggctatgtc gtctcatttg caccaggcca agcaggagca gatgcaacct atggtcacgt
    81781 tgctgttgta gagcaaatca aagaagatgg ttctatctta atttcagagt caaatgttat
    81841 gggactaggc accatttcct atcggacgtt cacagctgag caggctagtt tgttgaccta
    81901 tgtcgtaggg gacaaactcc caagaccata actccacaac caagaagcta cctgcctgtt
    81961 gaccaatctc aaaaagagac agcgtcaact tagaatgagg ttcatcagat gataaagaaa
    82021 gtgaccaccc cgagtcaaaa aacaaaaaaa cgtgttcgta atggctacct cctaaaacta
    82081 ggtacagcct gtttactctt aagtatactc agttatggca ttggtctttt gggccagcct
    82141 agcatggaaa atacgtttat gggaatagcg agtgttgcca tgttaggaag tgtctgtttc
    82201 tttattatct ttgctctaaa ccgtatcttt gacgcactag aggacaattt gcgagattag
    82261 agtaataggt cacataatct tccaataatt tagagcacaa gctaagttat tggaagtttt
    82321 tttgtctttt gagagccatg atgccatcaa aaagccaaac actccttatg atgtgagagt
    82381 cacatggcta aaattaaaag caaaatagac cccaaagccc tgttttctca aaacagccaa
    82441 cgaaaaaaga caagttaacc agttcataaa aaacatcgta gaaacgtttt caagagctaa
    82501 tgttggagta aattgactga agtatgatag aatttttaat gaatgtaaca ataatgtcac
    82561 agataaaaac cgaaaacagc aaaaataatt aaattgaata taaaaaagtt aattaagtga
    82621 gtgataataa agaaatgaag ttcaaaaaat ataaataaaa taaaacacca gaactgccaa
    82681 aagcagtgaa tgacataaat gtcgctaaaa aaatagatag aagagtctaa aatttcagtt
    82741 ttaggtcacg ttttatgaat agaaatcaga atgatgacct taagttgtga tttgcgcgtc
    82801 attgaccgct ttcttcgttt taatgaaaga atttgaaaga tattttatgg tatacttttc
    82861 cttaatatgg ttcatacgga cttgataaat ctattcacaa aaataataaa aaattaagat
    82921 aaggacatga agttaatgca tgtaagtaaa ttgtttacta gccaacaatg gagagaattg
    82981 aaactgatct catatttaac agaaaactcc aatgctatcg gagttaaaga taaggagctt
    83041 agcaaggctc tcaatatttc catgttaaca ttacagtcat gcctcactaa tatgcagttt
    83101 atgaaagaag taggtggaat tacctacaaa gacggctata ttaacatttg gtatcaccag
    83161 tgttgtgggc tacaagaggt ctatcaaaaa gctcttcgag aatcgccttc tttgaaatta
    83221 ctggagcttt tgtttttcag agactttagt tccttagaag agttagctga agagctgttt
    83281 gtcagcttat ctaccctcaa acgcctcatc aaaaaaacca acacttactt gtctcatacc
    83341 tttgctatta gtatcgtgac aagtccagtg caggtgtcag gagatgagag gcaaattcgc
    83401 ctgttttacc tcaagtattt ttcagaagcc tataaaatct cagaatggcc atttggggac
    83461 attttaaacc tgaaaaactg tgaacgccta ttgagcttat tgatcaaaga agtagatgtc
    83521 aaagttcatt ttacgctatt tcagcactta aaaatcttaa gtggtgtcaa cttgatccgt
    83581 tactacaagg ggtattcttg cagttataac aataaaaaaa ccagtcaccg tttttctcaa
    83641 cttatccaac attcctcaga aatccaggat ctttctcgct tgttctacct caaatttggg
    83701 ttacatctcg acgagtatac catagctgaa atgttttcta accatcttaa cgacaagcta
    83761 gaaattggct gtgcttttga gattatcaat caagacccaa catcaggagg cagacaagta
    83821 accaactgga tccatctatt agatgagatg gaaatcaagc tcaatctcag catcaccaat
    83881 aaatacgaag ttgccgtaac cctccataac gcttcggtgt taaacgaaga agacattaca
    83941 gccaattatt tgctgtttga ttataaaaag agttacctga acttttacca aaaagaacac
    84001 cctcgtatct atgaagcctt tgtgacaagt gtcgagaagc tgatgcaggc agataatgct
    84061 caagttagca aagaactgat caatcagctc acttattgtt tctttattac ctgggaaaat
    84121 agtttcttaa aagtaaatca aaaagatgaa aaagtacgac tcctagtgat agagagaagt
    84181 tacaatagtg tcggtaattt tttgaaaaag tacatcggtg agtttttcag cattactaat
    84241 tttgatgagt tagattgtct gacaattgat ctagtagaga ttgaaaaaca gtacgatgtt
    84301 atcgtgacag atgttatggt gggtaaaagc gaagagttag agattttctt tttctacaag
    84361 atgatcccag aagctattat tgatagatta aacgaatttt tgaacgttag tttcacagat
    84421 aacaacgtta tggtcaaaaa cctcgaagcc ccttcccctt caaaatctca tagcgacaaa
    84481 gaggtacaaa agccagaaaa gccagacaat tcagttaaac aagcaacatc atcataggat
    84541 ttcagacgtc atggtaagaa aaaaagaatc atttacagcc catagaggta aggtcaaaag
    84601 ctgaaaacag ctcaaaaaaa ctgaccttta ccttttggct ttttttattt agaataactt
    84661 tattggagag atgcttaatc taatttaagc acaattctta gaaagttaag aaataaggag
    84721 taaacaatgt ctaaaagaaa tccaaacaaa cactactcac tgagaaagtt aaaaacaggt
    84781 actgcatcag tagcagtagc tttgacagtt ttggggactg gattagcaaa cacaactgat
    84841 gtaaaggctg agactgagca tcttgatgtt gtgctttcag caaaagaagc taacaaagta
    84901 ttcgaagagc gcaaagcctt ggaaaaacaa gcgcgtgatt tgggtgacac tattaatcac
    84961 atgtcacaaa ccattagcga gcaaagccgc aagattgcag cactaaagtc tgaagcagaa
    85021 cttaaaaacc aacaagctct tgaagcttta aataataaaa atgagcagat tgctaaatta
    85081 accaacgaaa acgcacagtt aaaagaagcc attgaagatt atgtgcaaac tatccaaaac
    85141 gctagtcgtg aaatggcagc aaaacaacaa gaacttgcag ctgcaaaaag ccagttagag
    85201 gcaaaaaatg ctgagattga ggcattgaaa caacaagatg cctctaagac tgaggaaatt
    85261 gctaaattgc aatcagaagc agcaacttta gaaaacctcc taggttcagc taagcatgag
    85321 ttgactgaat tgcaagctaa gctagataca gcaactgctg aaaaagcaaa actagaatca
    85381 caagtaacaa ccttagaaaa cctcctaggt tcagctaagc gtgaattgac tgaattgcaa
    85441 gctaagctag atgcagctaa cgctgaaaaa gaaaagctcc aatcacaagc agcagcccta
    85501 gaaaaacaac tagaagcaac taaaaaagag ttagctgatt tacaggctaa attagcagca
    85561 accaaccaag aaaaagaaaa gttagaagct gaagcaaaag ctcttaaaga gcaattagca
    85621 aaacaagctg aagagcttgc taagctaaaa gcagataaag cttcaggagc tcaaaaacca
    85681 gatactaaac ctggcaataa agaggttcca acaagaccat cacaaacaag aacaaacact
    85741 aataaagctc ctgtggcgca aacaaagaga caattaccgt caacaggcga agaaacaacc
    85801 aacccattct tcactgcagc agcattgaca gtgattgcat ctgcaggcgt acttgcccta
    85861 aaacgcaaag aagaaaacta agcccaaccc acactatctt ttctagccca agaaaaaaac
    85921 aaaaaaagag gaagaccatt cctctttttt tgaacggtta aacagcaaaa aggtcaaaaa
    85981 ggtactaaag tctcaaaaac ctggtcttta ccttttaccg cttattcttt agaatagaat
    86041 tattagagag aagtcttaga aaaatgaggc taattcccta aagatgaaaa aataaggagc
    86101 aaataatggc tagaaaagat acgaataaac agtattcgct tagaaaatta aaaacaggta
    86161 cagcatccgt agcggtcgct gtggctgttt taggagcagg ctttgcaaac caaacaacag
    86221 ttaaggctgc ggagattaaa aagcctcagg ctgattcagc gtggaactgg cctgaagaat
    86281 ataacgcgtt acttaaggaa aatgaggagc tcaaggtaga acgtgaaaaa tatctatcct
    86341 atgctgacga taaagaaaaa gatcctcaat acagagcatt aatgggtgaa aatcaagatc
    86401 ttcgaaaaag agagggacaa tatcaggaca aaatagaaga acttgaaaaa gaaagaaaag
    86461 aaaaacaaga aagacaagaa agacaagaaa aattagaacg tcaacatcaa gataagcatt
    86521 atcaagaaca acaaaagaaa catcagcaag aacaacaaca attagaagca gaaaaacaaa
    86581 aattagctaa agaaaagcaa atctcagacg caagccgtca aggtctaagc cgtgaccttg
    86641 aagcgtctcg tgcagctaaa aaagagcttg aagctaagca ccaaaagcta gagactgagc
    86701 accaaaaact caaagaggaa aaacaaatct cagatgcaag ccgtcaaggt ctaagccgtg
    86761 accttgaagc atctcgcgaa gctaagaaaa aagtagaagc agacctagct gctcttactg
    86821 ctgagcacca aaaactcaaa gaggaaaaac aaatctcaga cgcaagccgt caaggtctaa
    86881 gccgtgacct tgaagcgtct cgcgaagcta agaaaaaagt agaagcagac ttagcagaag
    86941 caaatagcaa acttcaagcc cttgaaaaac taaacaaaga gcttgaagaa ggtaagaaat
    87001 tatcagaaaa agaaaaagct gagttacaag caagactaga agctgaagca aaagctctta
    87061 aagagcaatt ggctaaacaa gctgaagaac ttgccaaact aaaaggcaac caaacaccaa
    87121 acgctaaagt agccccacaa gctaaccgtt ctagatcagc aatgaagcaa caaaagagaa
    87181 cgttaccgtc aacaggcgaa gcagctaacc cattctttac agcagcagct gcaacagtga
    87241 tggtatctgc aggtatgctt gctctaaaac gcaaagaaga aaactaagct attagactga
    87301 tgctaaagct aagagagaat caaatgattc tctctttttg agtggctaag taactaacaa
    87361 tctcatttag accaaaaaat gaaaatagtt caaaaagctg gcctttactc cttttgatta
    87421 accatatata acaaaaaaca ttagggaagt aatagtaata ttaagtttgt ttcctcaata
    87481 aaatcaagga gtagataatg gctagacaac aaaccaagaa aaattattca ctacggaaac
    87541 taaaaaccgg tacggcttca gtagccgttg ctttgaccgt tttgggcgca ggttttgcaa
    87601 accaaacgga agtaagagct gaaggggtaa aagcgactaa gaacttgtca gaggaggcta
    87661 aatatgacac attgaaagat gagaatactg gtttacgtgg tgatcagaca aaattagtaa
    87721 aaaaacttga agaagaacaa gagaagagca aaaatctaga aaaagaaaaa cagaagttag
    87781 aaaaccaagc ccttaacttt caagatgtaa ttgaaactca ggaaaaagaa aaagaagatc
    87841 tcaaaacaac tttagctaag actactaaag aaaatgagat ttcagaagct agccgtaaag
    87901 ggttaagccg agacttagaa gcttctcgtg cagctaaaaa agagctagaa gctaagcatc
    87961 aaaaattaga agcagaaaac aaaaaactaa cagaagccaa tcaggtttca gaagctagtc
    88021 gtaaaggtct aagtaacgac ttagaagctt ctcgtgcagc taaaaaagaa ctagaagcta
    88081 agcaccaaaa attagcagaa gaacatcaag tttcagagac tagccgcaag ggtctaagcc
    88141 gtgaccttga agcatcacgt gaagctaata agaaggttac atctgagtta acacaagcaa
    88201 aagctcaact ctcagcgctt gaagaaagta agaaattatc agaaaaagaa aaagctgagt
    88261 tacaagcaaa actagatgca caaggaaaag ccctcaaaga acaattagca aaacaaactg
    88321 aagagcttgc aaaactaaga gctgaaaaag cagcaggttc aaaaacacct gctaccaaac
    88381 cagctaataa agaaagatca ggtagagctg ctcaaacagc tacaagacct agccaaaata
    88441 aaggaatgag atcacaatta ccgtcaacag gcgaagcagc caacccattc tttacagcag
    88501 cagctgcaac agtgatggta tctgcaggta tgcttgctct aaaacgcaaa gaagaaaact
    88561 aagcctttag aacttggttt ttgtaacggt gcaatagaca aaagcaagca aggccaaaaa
    88621 ctgagaaagt cctaaaaagc tggcctttac ccctcaaaat taatgtttta taatgaagat
    88681 gttagtaata taattgataa atgagataca tttaatcatt atgacaaaag caagaaaaat
    88741 agctgtatca tatgcaaata acccctgttt gctctttaaa aaagacgtta tccttatttc
    88801 tccacgcaca gatggacagc taggagagaa tcgtttgatt ctctcttttc ttaatggtca
    88861 taaagacaaa gtctctcatc atgaaaggac gacacattgc gtaaaaaaca aaaattacca
    88921 tttgataaac ttgccattgc gctcatgtct acgagcatct tgctcaatgc acaatcagac
    88981 attaaagcaa atactgtgac agaagacact cctgctaccg aacaagccgt agaaacccca
    89041 caaccaacag cggtttctga ggaagcacca tcatcatcaa aggaaactaa aatcccacaa
    89101 actcttggtg atgcagaaga aacagtagca gatgacgcta atgatctagc ccctcaagct
    89161 cctgctaaaa ctgctgatac accagcaacc tcaaaagcga ctattaggga tttgaacgac
    89221 ccttctcagg tcaaaaccct gcaggaaaaa gcaggcaagg gagctgggac tgttgttgca
    89281 gtgattgatg ctggttttga taaaaatcat gaagcgtggc gcttaacaga caaaactaaa
    89341 gcacgttacc aatcaaaaga agatcttgaa aaagctaaaa aagagcacgg tattacctat
    89401 ggcgagtggg tcaatgataa ggttgcttat taccacgatt atagtaaaga tggtaaaacc
    89461 gctgtcgatc aagagcacgg cacacacgtg tcagggatct tgtcaggaaa tgctccatct
    89521 gaaacgaaag aaccttaccg cctagaaggt gcgatgcctg aggctcaatt gcttttgatg
    89581 cgtgtcgaaa ttgtaaatgg actagcagac tatgctcgta actacgctca agctatcaga
    89641 gatgctgtca acttgggagc taaggtgatt aatatgagct ttggtaatgc tgcactagct
    89701 tacgccaacc ttccagacga aaccaaaaaa gcctttgact atgccaaatc aaaaggtgtt
    89761 agcattgtga cctcagctgg taatgatagt agctttgggg gcaaaacccg tctacctcta
    89821 gcagatcatc ctgattatgg ggtggttggg acgcctgcag cggcagactc aacattgaca
    89881 gttgcttctt acagcccaga taaacagctc actgaaactg ctacggtcaa aacagacgat
    89941 catcaagcta aagaaatgcc tgttctttca acaaaccgtt ttgagccaaa caaggcttac
    90001 gactatgctt atgctaatcg tgggatgaaa gaagatgatt ttaaggatgt caaaggcaaa
    90061 attgccctta ttgaacgtgg tgatattgat ttcaaagata agattgcaaa cgctaaaaaa
    90121 gctggtgctg taggggtctt gatctatgac aatcaagaca agggcttccc gattgaattg
    90181 ccaaatgttg atcagatgcc tgcggccttt atcagtcgaa aagacggtct cttattaaaa
    90241 gacaattcta aaaaaaccat caccttcaat gcgacaccta aggtattgcc aacagcaagt
    90301 ggcaccaaac taagccgctt ctcaagctgg ggtttgacag ctgacggcaa tattaagcca
    90361 gatattgcag cacccggcca agatattttg tcatcagtgg ctaacaacaa gtatgccaaa
    90421 ctttctggaa ctagtatgtc tgcgccattg gtagcgggta tcatgggact attgcaaaag
    90481 caatatgaga cacagtatcc tgatatgaca ccatcagagc gtcttgattt agctaaaaaa
    90541 gtattgatga gctcagcaac taccttatat gatgaagatg aaaaagctta tttttctcct
    90601 cgccaacaag gagcaggagc agtcgatgct aaaaaagctt cagcagcaac gatgtatgtg
    90661 acagataagg acaatacctc aagcaaggtt cacctgaaca atgtttctga taaatttgaa
    90721 gtaacagtaa cagttcacaa caaatctgat aaacctcaag agttgtatta ccaagcaact
    90781 gttcaaacag ataaagtaga tggaaaacac tttgccttgg ctcctaaagc attgtatgag
    90841 acatcatggc aaaaaatcac aattccagcc aatagcagca aacaagtcac cgttccaatc
    90901 gatgctagtc gatttagcaa ggacttgctt gcccaaatga aaaatggcta tttcttagaa
    90961 ggttttgttc gtttcaaaca agatcctaaa aaagaagagc ttatgagcat tccatatatt
    91021 ggtttccgag gtgattttgg caatctgtca gccttagaaa aaccaatcta tgatagcaaa
    91081 gacggtagca gctactatca tgaagcaaat agtgatgcca aagaccaatt agatggtgat
    91141 ggattacagt tttatgctct gaaaaataac tttacagcac ttaccacaga gtctaaccca
    91201 tggacgatta ttaaagctgt caaagaaggg gttgaaaaca tagaggatat cgaatcttca
    91261 gagatcacag aaaccatttt tgcaggtact tttgcaaaac aagacgatga tagccactac
    91321 tatatccacc gtcacgctaa tggcaagcca tatgctgcga tctctccaaa tggggacggt
    91381 aacagagatt atgtccaatt ccaaggtact ttcttgcgta atgctaaaaa ccttgtggct
    91441 gaagtcttgg acaaagaagg aaatgttgtt tggacaagtg aggtaaccga gcaagttgtt
    91501 aaaaactaca acaatgactt ggcaagcaca cttggttcaa cccgttttga aaaaacgcgt
    91561 tgggacggta aagataaaga cggcaaagtt gttgctaacg gaacctacac ctatcgtgtt
    91621 cgctacactc ctattagctc aggtgcaaaa gaacaacaca ctgattttga tgtgattgta
    91681 gacaatacga cacctgaagt cgcaacatcg gcaacattct caacagaaga ttgtcgtttg
    91741 acacttgcat ctaaaccaaa aaccagccaa ccgatttacc gtgagcgtat tgcttacact
    91801 tatatggatg aggatctacc aacaacagag tatatttctc caaatgaaga tggtaccttt
    91861 actcttcctg aagaggctga aacaatggaa ggcgctactg ttccattgaa aatgtcagac
    91921 tttacttatg ttgttgaaga tatggctggt aacatcactt atacaccagt gactaagcta
    91981 ttggagggcc actctaataa gccagaacaa gacggttcag atcaagcacc agacaaaaaa
    92041 ccagaaacta aaccagaaca agatggttca gatcaaggac cagacaaaaa accagaaact
    92101 aaaccagaac aagacggttc agatcaagca ccagacaaaa aaccagaagc taaaccagaa
    92161 caagacggtt caggtcaaac accagataaa aaaccagaaa ctaaaccaga acaagatagt
    92221 tcaggtcaaa caccaggtaa aactcctcaa aaaggtcaac cttctcgtac tctagagaaa
    92281 cgatcttcta agcgtgcttt agctacaaaa gcaacaacaa gagatcagtt accaacgact
    92341 aatgacaagg atacaaatcg tttacatctc cttaagttag ttatgaccac tttcttcttg
    92401 ggattagtag ctcatatctt taaaacaaaa cgcactgaag attagtacaa ctgatcagat
    92461 ggctactatt gatgatgagt tagatcagtc ttcttttcaa aagaaggcat agcagtataa
    92521 aaatagatat gtgaggacaa tatgcttaga gcagaaaata acaaacacag ccgctattcc
    92581 attcgcaaac tgagcgttgg ggtaacgagt atagcaattg cgagtctctt tttaggaaag
    92641 gttgcctatg ccgttgatgg catccctcca atctctctta ctcaaaggac tacagccact
    92701 acatcagaaa aatggcatca tattaatgat gatggctcta ttcctttagg tataagctta
    92761 gaagatgcca aagaggattt taaaaaagaa gtaaaagaat cacttttgtc tgaagaacaa
    92821 aaagaaacgt ataaacgaaa aattgatgct gaaacagata aagataaact attgttaacg
    92881 tatcatagtg agtatatgac agccgttaag actcttccaa cgtctactga gccagttgag
    92941 acacccgtgc aggggacaca ggcttcagat tcgatggtga cagatgattc aacatcagtt
    93001 acgactgatt ctcctgagaa aacaccatct acagaaacac cggctccat
//
LOCUS       DATTYN010000005        92270 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.05, whole genome shotgun sequence.
ACCESSION   DATTYN010000005 DATTYN010000000
VERSION     DATTYN010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 92270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92270
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.05"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(252..884)
                     /locus_tag="VB649_000463"
     CDS             complement(252..884)
                     /locus_tag="VB649_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEP1669442.1"
                     /translation="MVENTKLLCSWVWLLALAILITIYSTWLWYPLEVDHLKLEQVVF
                     MSKDAILHNYNGLLNYLTNPFVTRLEFANFHSSADGLKHFADVKWLFHLTQVVFLGLL
                     YPTLKTFTQRLQTKRFWLLQKPLILAALFPLMIGLMASFIGFEHFFTLFHQVLFVGDS
                     SWLFDPLKDPVIWILPEVFFLHCFLFFMIVYEIILWSLVGLARWQRLNVE"
     gene            complement(884..1648)
                     /locus_tag="VB649_000464"
     CDS             complement(884..1648)
                     /locus_tag="VB649_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEP1669443.1"
                     /translation="MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQERGIPYLLVTNN
                     TTRTPEMVQSMLANQFHVETSIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     AAGYVEELENPAYVVVGLDSQMTYEMLAIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQN
                     DIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL"
     gene            complement(1648..2400)
                     /locus_tag="VB649_000465"
     CDS             complement(1648..2400)
                     /locus_tag="VB649_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEP1669444.1"
                     /translation="MGLSYQEELTLPFELCDVKSDIKLPLLLDYCLMVSGRQSAQLGR
                     SNNNLLVDYKLVWIVTDYEITIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGG
                     LLVDILAYFALLNPDTRKVATIPEDLVAPFETDFVKKLHRVPKMPLLEQSIDRDYYVR
                     YFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQ
                     LTSYHQITSDGQLNAQAMIEWRAIKQTESETD"
     gene            complement(2410..3540)
                     /locus_tag="VB649_000466"
     CDS             complement(2410..3540)
                     /locus_tag="VB649_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEP1669445.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLKALIQE
                     FDSYGIRNLKTLYIGGGTPTAITAKQLEYLLNHLERNLNLDDLEEFTIEANPGDLTPE
                     KIAVLQRSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKAAGFHNISIDLIY
                     ALPGQTLDQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEM
                     FEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQN
                     RVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFGMSFEE
                     RYGNIVRELQNQGLLVKDDAFVRMTKKGLFLGDSVAERFILD"
     gene            complement(3603..4244)
                     /locus_tag="VB649_000467"
     CDS             complement(3603..4244)
                     /locus_tag="VB649_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669446.1"
                     /translation="MTKQQIEKLADLLPPFAATLYLDMIPEFQEGYASYVYQTQKEDI
                     QKRRIKQLTKNFERLLDTPSFYVMPVTRKTAEQLLADKSLAYHLLSTVAANQVFAAAV
                     NEDQTLFQVLRNGARVAFVILQEKGEFLEMTLGILETVTENEVPAAIVEAVQTYLLAD
                     MQEKLPSLSIMVSQESSKLFYQEQGFVLLAKGCKPGNENDSDVCQLVKYFSKP"
     gene            complement(4367..5722)
                     /locus_tag="VB649_000468"
     CDS             complement(4367..5722)
                     /locus_tag="VB649_000468"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEP1669447.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKV
                     FVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKY
                     EKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGFNINDGVGS
                     THPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLA
                     HNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAI
                     ANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCD
                     N"
     gene            complement(5776..6732)
                     /locus_tag="VB649_000469"
     CDS             complement(5776..6732)
                     /locus_tag="VB649_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEP1669448.1"
                     /translation="MKRFLNSRPWLGMVSVFFAILLFLTAASSNHNNSSSQIYSPIET
                     YTHSLKDVPIDMKYDSDKYFISGYSYGAEVYLTSTNRIKLDSEVNNDTRNFKIVADLT
                     HSHPGTVNVNLRVENLPSGVTATVSPDKISVTIGKKESKVFPVRGSVDAKQIANGYEI
                     SKIETGVDKVEVTSDESTIALIDHVVAKLPDDQMLDRNYSSRVTLQAVSADGTILASA
                     IDPAKTNLSVAVKKITKSVPIRVEAVGMMDDSLSDIQYKLSKQTAVISGSREVLEDID
                     EIIAEVNISDVTKNTSKTVSLSSSQVSIEPSVVTVQLTTTKK"
     gene            complement(6729..7580)
                     /locus_tag="VB649_000470"
     CDS             complement(6729..7580)
                     /locus_tag="VB649_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEP1669449.1"
                     /translation="MNNLSSIDIKFLLSLFADPWLLAVHLLDILIVAYLIYRFIKALT
                     GTKIMSLVQGVIFFLVLRFIAEWIGFTTITYLMNQVITYGVIAGVVIFTPEIRAGLEK
                     FGRSTQVFLQKQYVSSESALVDALIKSVAYMGPRKIGALIVIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVGQNKIVAACAYLPLSESKAISKEFGTRHRAAI
                     GLSENSDALTIIVSEETGAISVTRKGQFLHDLSTDEFETVLRTYLMSDSNVSLPWYKK
                     ILGGKSK"
     gene            7687..9030
                     /locus_tag="VB649_000471"
     CDS             7687..9030
                     /locus_tag="VB649_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEP1669450.1"
                     /translation="MKMKTLLGIIAGKAAQSILTKLGRGSTYPGRLALACNKDILKDL
                     SKDYDIVVVTGTNGKTLTTALTVGILKEAFGEIITNPSGANMITGITSTFLAAKKGKS
                     ERQIAVLEIDEASLPRITTYLKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGARNAPK
                     ATILANGDSPIFSSKDIVNPVQYYGFDTAKHAPQLAHYNTEGILCPKCEHILQYRLNT
                     YANLGDFVCLNCQFQRPTLDYQLTELTAITHQSSEFVIDGQNYKINVGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFNKSKAVFGRQETFTIGDKSCTLILIKNPVGASQALEMIQ
                     LADYPFSLSVLLNANYADGIDTSWIWDANFELITQMPITEINAGGVRHSEIARRLRVT
                     GFDDTKIKQAEKLEQIIETIEKQEAKHAYILATYTAMLEFRSLLADRHVVEKEMI"
     gene            9030..9821
                     /locus_tag="VB649_000472"
     CDS             9030..9821
                     /locus_tag="VB649_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEP1669451.1"
                     /translation="MTYTSLKSPENQDYIYDLNIAHLYGNLMNTYGDNGNILMLKYVA
                     EKLGARVTVDIVSINDTFEQDDYDIVFFGGGQDYEQSIVAKDLPSKKAALADYIANNK
                     VVLAICGGFQLLGQYYVQANGVKIDGLGIMGHYTLNQHQNRFIGDIKIHNDEFNETYY
                     GFENHQGRTFLSGDEKPLGRVVYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVNLA
                     YRLVTTALKKKYGSAISLPSYDDILKQEITEEYADLKSKASFNKV"
     gene            complement(9930..10919)
                     /locus_tag="VB649_000473"
     CDS             complement(9930..10919)
                     /locus_tag="VB649_000473"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEP1669452.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVEEDELFILWINEPAIIIG
                     KHQNAIQEINKEYIDEHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTAEGAFDFKTFS
                     QPVIATLADLGVTANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKITVEEFSDKILTKMKETYPDMTEYVLS
                     EDELAKIEQSAKEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSIIKNLKIY
                     GDFFGIKDVQDIENLLIGCKYEYRDVFERLKTIDTTQYFSRMTVEEVAKAIVS"
     gene            11152..13569
                     /gene="hylA"
                     /locus_tag="VB649_000474"
     CDS             11152..13569
                     /gene="hylA"
                     /locus_tag="VB649_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEP1669453.1"
                     /translation="MNTYFCTHHKQLLLYSNLFLSFAMMGQGTAIYADTLTSNSEPNN
                     TYFQTQTPTTTDSEKKVVQPQQKDYYTELLDQWNSIIAGNDAYDKTNPDMVTFHNKAE
                     KNAQNIIKSYQGPDHENRTYLWEHAKDYSASANITKTYRNIEKIAKQITNPESCYYQD
                     SKAIAIVKDGMAFMYEHAYNLDRENHQTTGKENKENWWVYEIGTPRAINNTLSLMYPY
                     FTQEEILKYTAPIEKFVPDPTRFRVRAANFSPFEANSGNLIDMGRVKLISGILRKDDL
                     EISDTIKAIEKVFTLVDEGNGFYQDGSLIDHVVTNAQSPLYKKGIAYTGAYGNVLIDG
                     LSQLIPIIQKTKSPIEADKMATIYHWINHSFFPIIVRGEMMDMTRGRSISRFNAQSHV
                     AGIEALRAILRIADMSEEPHRLALKTRIKTLVTQGNAFYNVYDNLKTYHDIKLMKELL
                     SDTFVPVQKLDSYVASFNSMDKLALYNNKHDFAFGLSMFSNRTQNYEAMNNENLHGWF
                     TSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTS
                     LSDDAFVASKKLNNTSALAAMTFTNWNKSLTLNKGWFILGNKIIFVGSNIKNQSSHKA
                     YTTIEQRKENQKHPYCSYVNNQPVDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPT
                     TLSISKALQTGKWQNIKADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTRQ
                     EFETYISKLDIDLLENNDKLAAVYDHDSQQMHVIHYEKKATMFSNHNLSHQGFYSFPH
                     PVKQNQQ"
     gene            complement(13857..13934)
                     /locus_tag="VB649_000475"
                     /pseudo
     CDS             complement(13857..13934)
                     /locus_tag="VB649_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(14244..16007)
                     /gene="lpdA"
                     /locus_tag="VB649_000476"
     CDS             complement(14244..16007)
                     /gene="lpdA"
                     /locus_tag="VB649_000476"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEP1669454.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAEGESVEVSSPAASDVNVARTTEDL
                     EAAGLEVPKAPAQAASAAPKAALADDEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVEK
                     SEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTVV
                     KTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGSQTIKGRNVILATGSKVSRINIPG
                     IDSKLVLMSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVDVTVIEMADRIIPAM
                     DKEVSLELQKILSKKGMKIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRVP
                     QMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAM
                     HGNTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASNE
                     AHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMESELTVDELLLSIHGHPTFSE
                     VMYEAFADVLGEAIHNPPKRK"
     gene            complement(16334..17743)
                     /locus_tag="VB649_000477"
     CDS             complement(16334..17743)
                     /locus_tag="VB649_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEP1669455.1"
                     /translation="MAFEIIMPKLGVDMQEGEIIEWKKEEGDTVNEGDILLEIMSDKT
                     NMELEAEDSGVLLKIVRPAGDTVPVTEVIGYIGAEGESVDTIASSEKTTEIPVPASAD
                     AGPTVAPKENVASPAPQVAATAIPQGNGGKVRATPAARKAAAEMGIDLGQVPGTGPKG
                     RVHKEDVENFKGAQPKASPLARKIAADKGIDLATVSGTGFNGKVMKEDIMAILEAAKP
                     AEAKAPAAKEEKVVDLPEGVEHKPMSAMRKAISKGMTNSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGMAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLIVPVIHGADKMSLSDFVLASKDVIKKAQTGKLKAAEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGVGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(17928..18926)
                     /locus_tag="VB649_000478"
     CDS             complement(17928..18926)
                     /locus_tag="VB649_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEP1669456.1"
                     /translation="MSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTS
                     VGMIEEFGPKRVKDTPISEAAISGAAIGAAITGLRPIVDVTFMDFVTIMMDAIVNNGA
                     KNNYMFGGGLITPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGL
                     LKSAIRDNNIVLFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLE
                     RVLQAAEEVAADGINVEVVDPRTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEI
                     ATMITESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVEKIKAAIVKMANKGN"
     gene            complement(18985..19953)
                     /locus_tag="VB649_000479"
     CDS             complement(18985..19953)
                     /locus_tag="VB649_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEP1669457.1"
                     /translation="MVTVSKEQYLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MGKAVEHVRGGNGPAIVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLT
                     SEGIATDDELDAIQAQVKKEVDDAYEFAQNSPDPELSVAFEDVWVD"
     gene            complement(20238..22145)
                     /locus_tag="VB649_000480"
     CDS             complement(20238..22145)
                     /locus_tag="VB649_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP1669458.1"
                     /translation="MIILQGNKLERSFSGDVLFQNISLQVDERDRIALVGPNGAGKST
                     LLKLLVGEETPTSGEVNTKKDLTLSYLAQNSRFESDKTIYEEMLKVFEALRQDEKRLR
                     QMEMDMATVSGQDLTRLMMDYDLLAERFRQQDGFTYEAEIKAILNGFKFDESMWQMTI
                     AELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLENYLANYQGALIIVSHD
                     RYFLDKVATVTLDLTPHGLDRYVGNYSRFMTLKAEKLVAEEKQFDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKIERLDKPTSARKSAHMTFQADKPSGNVVLTVEKAAI
                     GYNQHVLSEPINLDVHKLDAIAIVGPNGIGKSTLIKSVIGQIPFIKGEVKYGANVEIG
                     YYDQTQSHLTSSNTVLEELWQDFSTTPEVDIRNRLGAFLFSGDDVKKSVAMLSGGEKA
                     RLLLAKLSMENNNFLVLDEPTNHLDIDSKEVLENSLIDFDGTLLFVSHDRYFINRLAT
                     KVLEITENGSTLYLGDYDYYLEKKAELEELARLAAGETVEETKEASATDYQLQKANQK
                     ERRRLTRRYEEIEARLETIEERIGAIQEDMHACNDTIQLMTWQEEWDQLDQEQQLLME
                     EWESIAEQIES"
     gene            complement(22191..22517)
                     /locus_tag="VB649_000481"
     CDS             complement(22191..22517)
                     /locus_tag="VB649_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669459.1"
                     /translation="MKQLLAIILWLPKLIVKMFWHLIKGFLQTILLVTIIIIGLMYYS
                     NHSDSVLANKISIVTEQVVQIFDILTQKPSAKTRHGSGNSHSTFLVSAKEGNQRLKKS
                     SISFGN"
     gene            complement(22547..23332)
                     /locus_tag="VB649_000482"
     CDS             complement(22547..23332)
                     /locus_tag="VB649_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEP1669460.1"
                     /translation="MASIVIEYHSVVLGMDRKVSVIYPDQSEIPKKDQGDKDIPVLYL
                     LHGMGGNENSWQKRTAIERLLRHTNLIVVMPSTDLGWYTDTAYGLNYYRALSQELPQV
                     LAAFFPNMTQKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALDFSPETLLEGN
                     LGELAYWQGVFGQFDDPDLDKHYLKNMVAESDGKTKFYAWCGYEDFLFATNEKAIADF
                     QAQGLDIDYHKGHGKHEWYYWNQQLEVLLEWLPINYQKEERLS"
     gene            complement(23465..25126)
                     /locus_tag="VB649_000483"
     CDS             complement(23465..25126)
                     /locus_tag="VB649_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEP1669461.1"
                     /translation="MTDIKMIALGGVREYGKNFYLVEINDSMFILDAGLKYPENEQLG
                     VDLVIPNLDYVIENKGKVQGIFLSHGHADAIGALPYLLAEVSAPVFGSELTIELAKLF
                     VKSNNSTKKFNNFHVVDSDTEIEFKDGLVSFFRTTHSIPESMGIVIGTDKGNIVYTGD
                     FKFDQAAREGYQTDLLRLAEIGKEGVLALLSDSVNATSNDQIASESEVGEEMDSVISD
                     ADGRVIVAAVASNLVRIQQVFDSATAHGRRVVLTGTDAENIVRTALRLEKLMITDERL
                     LIKPKDMSKFEDHELIILEAGRMGEPINSLQKMAAGRHRYVQIKEGDLVYIVTTPSTA
                     KEAMVARVENLIYKAGGSVKLITQNLRVSGHANGRDLQLLMNLLKPQYLFPVQGEYRD
                     LAAHAKLAEEVGIFPENIHILKRGDIMVLNDEGFLHEGGVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSHDILRESAELVNTT
                     VGNYLKKDTFDWGELKGNVRDDLSKFLFEQTKRRPAILPVVMEVR"
     gene            complement(25330..26088)
                     /locus_tag="VB649_000484"
     CDS             complement(25330..26088)
                     /locus_tag="VB649_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669462.1"
                     /translation="MTKIIELINATVDVDNGFEDAKTILDNVTLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLSLTRGQIRILGQDVTHWPAEKRALYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGEKRSLASRKITEHLASFEDLVKRTGNGLEKHLETPAGLLSGGQRQAL
                     SLLMATLKKPALLLLDEHTAALDPKTSHSLMQLTDEFVTKDGLTALMITHHMEDALTY
                     GNRLIVMKDGNIIKDLNQMEKEQLTITDYYQLFD"
     gene            complement(26085..26954)
                     /locus_tag="VB649_000485"
     CDS             complement(26085..26954)
                     /locus_tag="VB649_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669463.1"
                     /translation="MIISSVSQGLIWGVLGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTAISLGWNPFLSTLLGMLSGALAGFLTGLLYTKGKMPTLLAGILVMTSCNSIMLMVM
                     GRANLGLHDHKRIQDCLPFSIDLNSLLTGLITVVIVISVLIYFLYTNLGQAYIATGDN
                     KDMAKSFGINTDWMEVMGLVVSNSLIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVIGSILYQFLISVVITLGFNTSYLKLISALVLALCLMIPV
                     VKERFFKGVRLTR"
     gene            complement(27130..27348)
                     /locus_tag="VB649_000486"
     CDS             complement(27130..27348)
                     /locus_tag="VB649_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669464.1"
                     /translation="MLLKKKIFLQLLLLRINTKTCDIKGQEKIIKNTLTEMNLDAKSD
                     NRLEDVTVIFIIFSFKMLYFRHVKNLAF"
     gene            complement(27299..28297)
                     /locus_tag="VB649_000487"
     CDS             complement(27299..28297)
                     /locus_tag="VB649_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP1669465.1"
                     /translation="MKNKSLIATLLVLTVIVIGSLLSKGVSKENRDLANQQNITIGIL
                     QFVTHEALDDIKRGIEDQLKKQMPQKQNVVIKVMNAEGDQSKIQTMSRQLVQSGSDIV
                     IGIATPAAQGLAATSKDIPVVMSAVSDPVGSRLVMQLDQPEANVTGLSNKVPVKQTID
                     LMKKLTPHVKTVGILYASNEDNSLSQVKEFRRLARKKGYQVISYAVPSTNEVPATMSV
                     MLGKVDAVFIPQDNTIASAFSSVMTTSKAAKIPVYTSVDRMVEKGGLAAISQNQYDLG
                     VQTANQVLKLIKGKRVVDVPVKVVDIGQPLINKNVAAELGIAIKKEDFPSASFIEN"
     gene            28651..30303
                     /gene="fbp54"
                     /locus_tag="VB649_000488"
     CDS             28651..30303
                     /gene="fbp54"
                     /locus_tag="VB649_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein Fbp54"
                     /protein_id="HEP1669466.1"
                     /translation="MSFDGFFLHHLTNELKENLLYGHIQKVNQPFERELVLTIRNHRK
                     NYKLLLSAHPVFGRLQITQADFQNPQVPNTFTMIMRKYLQGAVIEQLEQIDNDRIIEI
                     KVSNKNEIGDAIQATLIIEIMGKHSNIILVDRAENKIIESIKHVGFSQNSYRTILPGS
                     TYIDPPKTAAVNPFTITDVPLFEILQTQELTVKSLQQHFQGLGRDTAKELAELLTTDK
                     LKRFREFFARPTQANLTTASFAPVLFSDSHATFETLSDMLDHFYQDKAERDRINQQAS
                     DLIHRVQTELDKNRNKLSKQEAELLATENAELFRQKGELLTTYLSLVPNNQDSVILDN
                     YYTGEKIEIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTKQSITYFESVDYN
                     LSQASIDDIEDIREELYQAGFLKSRQRDKRHKRKKPEQYLASDGKTILMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLDPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPDQAKILSMKLS"
     gene            complement(30362..31609)
                     /locus_tag="VB649_000489"
     CDS             complement(30362..31609)
                     /locus_tag="VB649_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEP1669467.1"
                     /translation="MLNSEKMIASLDQQDLAHAEKYFQKALKEDDADSLIALGEYLES
                     IGFLPHAKRIYLQLADDYPELNINLAQIAAEDDAIEEAFLYLDKVSKDSPNYLSALLV
                     MADLYDMEGLTEVAREKLLQAVAISSEPLVIFGLAEIDMSLQYFKEAIDYYAQLDNRQ
                     ILELTGISTYQRIGRAYASLGKFEAAIEFLEKAVAIEYEDETVFELATLLYDQENYQK
                     ANLYFKQLETINPDYPGYEYGYALSLHEEHKTSEALRLVQQGLRKNAFDSQLLLLASQ
                     LSYELHDRQNAENYLLQAKEVAVDDEEILMRLVTLYFDAERFEEVIALNRETIDNVLT
                     KWTIAKAYHALEQEEVALALYNEISADLAENPEFLQDYAYLLREFGQFHKAIQMATAY
                     LRQVPDDVNMQDFLDHIKHQQSE"
     gene            complement(31599..32780)
                     /locus_tag="VB649_000490"
     CDS             complement(31599..32780)
                     /locus_tag="VB649_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEP1669468.1"
                     /translation="MPLIPDKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKIS
                     FLFMPVISFFAVIMLPLVISTILYYLTKPLVDLINHLGPNRTTSIFIVFGLITLLFVW
                     AISGFVPMVQTQLTSFIEDLPKYVGKVNEEANKFLENEWLVSYKPQLQDMLTHTSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKL
                     RVPMVRVLGDINKQLSGYVQGQVTVAIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMAMVQGPFMLVKVLVIFMIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPIYASVKVVIKELFDWYKKVSGLYDEEVLVIEEVKDHV
                     K"
     gene            complement(32838..33314)
                     /locus_tag="VB649_000491"
     CDS             complement(32838..33314)
                     /locus_tag="VB649_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEP1669469.1"
                     /translation="MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGE
                     TPDECARREILEETHLTVTEMAFKGIITFPEFTPGHDWYTYVFKVTGFEGDLISDEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY"
     gene            complement(33535..34575)
                     /gene="rfbB"
                     /locus_tag="VB649_000492"
     CDS             complement(33535..34575)
                     /gene="rfbB"
                     /locus_tag="VB649_000492"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEP1669470.1"
                     /translation="MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRA
                     NIEAILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLEDPSPFIHTNFI
                     GTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYS
                     STKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLYGE
                     GKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILEKMDQPKDAY
                     DHVTDRAGHDLRYAIDSTKLREELGWEPQFTNFSEGLEETIKWYTENETWWKAEKDAV
                     EAKYAKTQEVIK"
     gene            complement(34819..35412)
                     /locus_tag="VB649_000493"
     CDS             complement(34819..35412)
                     /locus_tag="VB649_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEP1669471.1"
                     /translation="MTETFFDKPLACREIKEIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MLPIGFPERFFEEGKLQNNVSFSRQHVLRGLHAEPWDKYISVADDGKVLGAWVDLREG
                     ETFGNVYQTVIDASKGMFVPRGVANGFQVLSETVSYSYLVNDYWALDLKPKYAFVNYA
                     DPSLGITWENLAAVEVSEADKNHPLLSDVKPLKPKDL"
     gene            complement(35412..36281)
                     /gene="rfbA"
                     /locus_tag="VB649_000494"
     CDS             complement(35412..36281)
                     /gene="rfbA"
                     /locus_tag="VB649_000494"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEP1669472.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDENMNAISIEEK
                     PEVPKSHFAVTGLYFYDNDVVEIAKNIKPSARGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYISKEDVHKLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(36339..37445)
                     /locus_tag="VB649_000495"
     CDS             complement(36339..37445)
                     /locus_tag="VB649_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEP1669473.1"
                     /translation="MKIAIIGAGIVGSTAAYYLQQSGQKEVTIFDHGQGQATKAAAGI
                     ISPWFSKRRNKVWYRMARLGADFYQQLINDLKEDGFATDFYQQNGIYVLKKQEEKLRD
                     LYELALARKVESPIIGELAIKNRKELGNDFKGLIGFDNCLYASGAARVEGAALCETLL
                     KASGYPVIRQKVTLKQQGSGYEIAGHYFDQVILAAGAWLPDLLRPLGYQVDVRPQKGQ
                     LLDYDVHHIISDTYPVVMPEGEIDLIPFNQGKISVGASHENDKGYDLEPDWQVLEKLE
                     MQALTYLPLLKEATQKTCRVGIRAYTSDYSPFYGQVSGLKNLYTASGLGSSGLTVGPL
                     IGYELAQLLLGHEGLLTPSDYSPEPYLLRSTGKA"
     gene            complement(37485..38273)
                     /locus_tag="VB649_000496"
     CDS             complement(37485..38273)
                     /locus_tag="VB649_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEP1669474.1"
                     /translation="MKAKTLIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLD
                     IRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNID
                     IVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTV
                     RLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAV
                     DPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL"
     gene            complement(38263..38949)
                     /locus_tag="VB649_000497"
     CDS             complement(38263..38949)
                     /locus_tag="VB649_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEP1669475.1"
                     /translation="MDSQLSNRLAQVAAYVPKGVKLLDVGSDHAYLPISLVETNQISA
                     AIAGEVVRGPYESALKNVTQSGLAEHIQVRLANGLAAFEEADDVTAITICGMGGRLIA
                     DILEAGKEKLQGIERLVLQPNNREDDLRAWLSVNAFKIVAETIMAENDKYYEIIVAEH
                     GEKALSATELRFGPYLSQEKSVVFKEKWQREMDKLAYALSCIPEEKTQERQLLLTKIQ
                     QIKEVIVHES"
     gene            complement(39021..39677)
                     /gene="nth"
                     /locus_tag="VB649_000498"
     CDS             complement(39021..39677)
                     /gene="nth"
                     /locus_tag="VB649_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEP1669476.1"
                     /translation="MRIGKARLAKVLTIIGQMFPEAKGELDWETPFQLLIAVILSAQT
                     TDKAVNKVTPGLWQSYPEIEDLAFAELSDVENALRTIGLYKNKAKNIIKTAQAIRDDF
                     KGQVPKTHKELESLPGVGRKTANVVLAEVYGVPAIAVDTHVARVSKRLNISSPDADVK
                     QIEADLMAKIPKKDWIITHHRLIFFGRYHCLAKKPKCEICPVQSYCKYYQNTYGKSKA
                     "
     gene            complement(39674..40357)
                     /locus_tag="VB649_000499"
     CDS             complement(39674..40357)
                     /locus_tag="VB649_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEP1669477.1"
                     /translation="MSFLEHYKSGNLVIPSALLFHYKDLFKSSDDFLVWQFFYLQNTT
                     KRDDLAPSQIAHALGKSVADINKIISSLTSQGLLDMRTIELTGEIEIIFDASPVLAKL
                     DQLFVSQTATEIDKQETPNHFKRLVDEFERELGRFLSPFELEDLEKTLRDDKTDPDLI
                     REALKEAVFNGKTNWKYIQAILRNWRKEGIVNLRQVEEHRRVREGEDLSQVTISEDFL
                     SAMNLWSDS"
     gene            complement(40438..40956)
                     /locus_tag="VB649_000500"
     CDS             complement(40438..40956)
                     /locus_tag="VB649_000500"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEP1669478.1"
                     /translation="MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYA
                     CDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIR
                     NYDYKVLMQFPG"
     gene            complement(41107..43317)
                     /gene="recJ"
                     /locus_tag="VB649_000501"
     CDS             complement(41107..43317)
                     /gene="recJ"
                     /locus_tag="VB649_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEP1669479.1"
                     /translation="MIKSKYSWKIKDKKPDDGFFKLAKTKGLTQTAAQLIYDRGIRTE
                     EALDEFLTADLSQLHDPYLLHDMAKAVPRIRQAIEEGERILIYGDYDADGMTSASIVK
                     ETLDMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEAVSLIITVDNGVAGHEAIRYAQ
                     EQEVDVIVTDHHSLPEELPEAFAIIHPEHPDADYPFKHLAGCGVAFKLATALLESLPT
                     DCLDLVAIGTIADMVSLTGENRVLVKNGLAMLKHTERVGLQELMSLSPIDLEHFNEDA
                     IGFQIAPQLNALGRLDDPNPAIELLTGFDDQEAQAIALMIKKKNEERKALVQDIFDQA
                     MAMVDPQKPVQVLAQAGWHPGVLGIVAGRIMETIGQTVVVLTIDNGFAKGSARSLEAI
                     NIFEALNGKRELFTAFGGHAGAAGMTLPVDNLEALSDFLCQFVIERGLDQTAKNTLTI
                     DERLSLDDLSLDILKSLDKLAPYGMNHQKPVFYVKDIRVSQARTIGQDQSHLKFKVSQ
                     GKASFDVLAFGQGSQLQEFRQATGLELAVTLSVNHWNGNTSLQFMLVDARVDGVQLLD
                     LRTKTAKVPEGIPTIEEDPNARVILINDIPEDFKAWRNQFVHKDFDAIYFKNQMKHPY
                     YLTGFGSREQFAKLYKTIYQFPEFDLRHKLTELSHYLNIEKLLLIKLIQIFEELSFVT
                     IDDGLMTVNPQAQKREISESHIYQDLKELVKFQEIMALASPKEMYDYLVKSNDQ"
     gene            complement(43314..44078)
                     /locus_tag="VB649_000502"
     CDS             complement(43314..44078)
                     /locus_tag="VB649_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEP1669480.1"
                     /translation="MAQRIIVITGASGGLAQAIVKQLPKEDSLILLGRNKERLEHCYQ
                     HIDNKECLELDITNPVAIEKMVAQIYQRYGRIDVLINNAGYGAFKGFEEFSAQEIADM
                     FQVNTLASIHFARLIGQKMAEQGQGHLINIVSMAGLIASAKSSIYSATKFALIGFSNA
                     LRLELADKGVYVTTVNPGPIATKFFDQADPSGHYLESVGKFTLQPNQVAKRLVSIIGK
                     NKRELNLPFSLAVTHQFYTLFPKLSDYLARKVFNYK"
     gene            complement(44078..45007)
                     /locus_tag="VB649_000503"
     CDS             complement(44078..45007)
                     /locus_tag="VB649_000503"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEP1669481.1"
                     /translation="MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYV
                     LTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTR
                     KTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKMVQDLEEVII"
     gene            complement(45022..45657)
                     /locus_tag="VB649_000504"
     CDS             complement(45022..45657)
                     /locus_tag="VB649_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEP1669482.1"
                     /translation="MNNYIDLAKTYGGFTSLDTNYLNHLLASLTDQQKLAFITPPPSV
                     INAYFAEIYQKQSPQAATDYYFNLSKALGLFTDQPSFEEEKPFVRLNLSGKAYGFAYQ
                     NDQEVALVFSEKAEPKKPELFFELTQIFPQYMVYEDKSQLKMQAKQFEQGECEDITPD
                     DTLLSKIYRLANGITMLKGFNVEELWALSQTFSGQKYYDFAQREFMIYITQ"
     gene            complement(45650..46888)
                     /gene="hflX"
                     /locus_tag="VB649_000505"
     CDS             complement(45650..46888)
                     /gene="hflX"
                     /locus_tag="VB649_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEP1669483.1"
                     /translation="MIETKRQQERVILLGVELQTTEHFDMSMTELANLAKTAGVKVMA
                     SFSQKRERYDSKTFIGSGKLDEIKAIVEADEIDAVIVNNRLTARQNANLEAVLEVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLTQVEKNRQTIRDRRVGSDTFKIGLIGYTNAGKSTIMNLL
                     TDDSHYEANELFATLDATTKQLYLENQFQATLTDTVGFIQDLPTELVAAFKSTLEESK
                     YVDLLLHVIDASDPNHSEQEKVVLNLLKELDMLNIPRLAIYNKVDIAEQFTATAFPNI
                     RVSARSKDSKILLRRLIIDQIRDQFVPFRIKMHQDKAYKLYDLNRVALLDHYTFDQEI
                     EDISGYISPKQQWRLDDFYE"
     gene            complement(46961..47860)
                     /gene="miaA"
                     /locus_tag="VB649_000506"
     CDS             complement(46961..47860)
                     /gene="miaA"
                     /locus_tag="VB649_000506"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEP1669484.1"
                     /translation="MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQL
                     DIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKAISDIVSCGKLPIIVGGT
                     GLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIR
                     ALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVNRMLENGLLEEAKWLYEH
                     YPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAI
                     TAPDYPQVVHDRVRDFLGQKEKS"
     gene            47994..48170
                     /locus_tag="VB649_000507"
     CDS             47994..48170
                     /locus_tag="VB649_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEP1669485.1"
                     /translation="MVKKYQFVKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFI
                     EENRKKAARRRVAR"
     gene            complement(48288..49196)
                     /locus_tag="VB649_000508"
     CDS             complement(48288..49196)
                     /locus_tag="VB649_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEP1669486.1"
                     /translation="MKHLKNPPLVMSGLALGTLSFGNLLATYVSIFNYLGILAALFIY
                     GILLVGMVRNLNDTKMQLRQPLIASVFPTFFMTGMLLSSLFLKVTGGCWLGFFTWWLF
                     FLGNLVLIVYYQYRFVFSFSWDNVFPSWSVLFVGIAMAALTAPASRQFLLGQVIFWVC
                     LLLTAVILPFMAKKTYGIGLGQAVMPNISTFCAPLSLLSASYLATFPRPQVGMVIFLL
                     ISSQLLYAFVVVQLPRLLNRPFNPGFSAFTFPFVISATSLKMTLSFLGWQGLGWQVLL
                     LGEVLLATALVTYVYGAYLRFLFQNK"
     gene            complement(49433..49852)
                     /locus_tag="VB649_000509"
     CDS             complement(49433..49852)
                     /locus_tag="VB649_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HEP1669487.1"
                     /translation="MPFIAKQTLKSQLIPQDNLLAESRFNEIMDFLTGDFPLVFRPMI
                     NPHRYTISQDNQALEKVKQASYKRMDIAMTHLDSLIGESGHVYRDQQTIADAYAYAMA
                     LWSQKTPKSYENYPHLAAFMAKMVEDSAVQQVLNAAH"
     gene            complement(50163..51149)
                     /locus_tag="VB649_000510"
     CDS             complement(50163..51149)
                     /locus_tag="VB649_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEP1669488.1"
                     /translation="MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLE
                     DNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKD
                     PEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFA
                     SEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA"
     gene            51344..51646
                     /locus_tag="VB649_000511"
     CDS             51344..51646
                     /locus_tag="VB649_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669489.1"
                     /translation="MTYELCLEYGTYPLSRVDAYWGEDQNPPTFIQEDRLLCHKLETM
                     NHLFHDLFVTIESQFHYVGFNMPEKRAQIRILYQEVATILKSKYKDYPIKIETFLL"
     gene            complement(51964..52035)
                     /locus_tag="VB649_000512"
     tRNA            complement(51964..52035)
                     /locus_tag="VB649_000512"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52000..52002),aa:Arg,seq:ccg)
     gene            complement(52148..53353)
                     /gene="rpsA"
                     /locus_tag="VB649_000513"
     CDS             complement(52148..53353)
                     /gene="rpsA"
                     /locus_tag="VB649_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEP1669490.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDRDADINDFVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     VGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVIEEAAKEARAEVFSKISEGAVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLSIDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVVEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAQAEGDNKEEKRQSRPRRPKRESRRDYELPETQTGFSM
                     ADLFGDIEL"
     gene            complement(53480..53551)
                     /locus_tag="VB649_000514"
     tRNA            complement(53480..53551)
                     /locus_tag="VB649_000514"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53517..53519),aa:Gln,seq:ttg)
     gene            complement(53603..53683)
                     /locus_tag="VB649_000515"
     tRNA            complement(53603..53683)
                     /locus_tag="VB649_000515"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53647..53649),aa:Tyr,seq:gta)
     gene            complement(53744..53974)
                     /locus_tag="VB649_000516"
     CDS             complement(53744..53974)
                     /locus_tag="VB649_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEP1669491.1"
                     /translation="MSKKDKKIEIQLIDHKVMVNETKIDGYQLQIGKRVVGEIAELDE
                     KFAVLKNDGVDCFFKTLEQAVENIIENYNLNH"
     gene            complement(54038..55105)
                     /locus_tag="VB649_000517"
     CDS             complement(54038..55105)
                     /locus_tag="VB649_000517"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEP1669492.1"
                     /translation="MKKSYNRKKQKRGTMMTIAIDWDNLGFEYHKLPFRYISYYKNGQ
                     WDKGQLTEDATLHISESAPALHYGQQAFEGLKAYRTKDGSIQLFRPDRNAVRLQATAD
                     RLLMPQVSTEQFIDAAKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPAEEYI
                     FTIFAMPVGNYFKGGLAPTNFIVSEAFDRAAPYGTGAAKVGGNYAGSLLPGKAAKSAG
                     FSDVIYLDPATHTKIEEVGAANFFGITANNEFVTPLSPSILPSITKYSLLQLAEERLG
                     MTVIEGDVPINELDKFVEAGACGTAAVISPIGGIQYKDNLHVFYSETEVGPVTRRLYD
                     ELVGIQFGDIEAPEGWIVKVD"
     gene            complement(55183..57642)
                     /gene="parC"
                     /locus_tag="VB649_000518"
     CDS             complement(55183..57642)
                     /gene="parC"
                     /locus_tag="VB649_000518"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEP1669493.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGI
                     IQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIVEVRDESDRTGLRIAIELKKEADSQTILNYLLKYTDLQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALI
                     RSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLS
                     AIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTR
                     GGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELT
                     DLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPW
                     RTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGV
                     KGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTK
                     PHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQILEVISKTGQTYEIALETLSLSERT
                     SNGSFISDTISDQEVLVARTR"
     gene            complement(57840..58658)
                     /locus_tag="VB649_000519"
     CDS             complement(57840..58658)
                     /locus_tag="VB649_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEP1669494.1"
                     /translation="MKLVIWQNTYSLQWDGTYHFALESYPMIQDWELEKIAAFCHYER
                     MNHREPQIICKDQVIVTKINQYLKHNNRKPPFTPSHKKVASTYDVSGKAVYGDWLSHT
                     CTVETAIAVFKSGKLLLAVKAFNRPAEELVKDSRNAAGDPADYFNYVMLGWSNTTSGY
                     RLAMERLIGHLPNDRELNELFIPGVSFHFSYEEVLAQEHYLFDGYHPAKVKNHLSLDA
                     LKACIIPLDQASLFEAIIPEVLKARCFYLPYHQEGLIEWTDSVYRFLVNLEMAD"
     gene            complement(58725..60674)
                     /gene="parE"
                     /locus_tag="VB649_000520"
     CDS             complement(58725..60674)
                     /gene="parE"
                     /locus_tag="VB649_000520"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEP1669495.1"
                     /translation="MTKKEITINNYNDDAIQVLEGLDAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGDDIKVVINKDGSVSVADSGRGMPTGQHAMGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSAWLEVEITRDGAVYRQRFENGGKPVTTLK
                     KVGTAPKSKSGTVVTFMPDDKIFSTIDFKFNTISERLKESAFLLKNVKMSLTDLRGDD
                     PIIEEFHYENGVQDFVEYLNEDKETLTPVIYMEGQDQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGEVASHLVRKAIKARDARE
                     AARKARDDSRNGKKNKKDKGLLSGKLTPAQSKNAKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLEDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVETGHVYIALPPLYKMSKGKGKTKKIAYAWTDGEL
                     EDLRREFGKGAILQRYKGLGEMNANQLWETTMDPETRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVKFTLEENTVF"
     gene            60809..61450
                     /gene="plsY"
                     /locus_tag="VB649_000521"
     CDS             60809..61450
                     /gene="plsY"
                     /locus_tag="VB649_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEP1669496.1"
                     /translation="MKLLLFITIAYLLGSIPTGLWIGQYFYHINLREHGSGNTGTTNT
                     FRILGVKAGTATLAIDMFKGTLSILLPIIFGMTSISSIAIGFFAVLGHTFPIFANFKG
                     GKAVATSAGVLLGFAPLYLFFLASIFVLVLYLFSMISLASVVSAIVGVLSVLIFPAIH
                     FLLPNYDYFLTFIVILLAFIIIIRHKDNISRIKHHTENLIPWGLNLSKQVPKK"
     gene            complement(61508..62776)
                     /locus_tag="VB649_000522"
     CDS             complement(61508..62776)
                     /locus_tag="VB649_000522"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEP1669497.1"
                     /translation="MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVI
                     DASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVE
                     TLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVL
                     KEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMN
                     PPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTTAPSGMTGLETSLSLG
                     LTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFV
                     SKASNSPFIGNKLKGVVKYTIADGEVVYPN"
     gene            complement(62908..63561)
                     /locus_tag="VB649_000523"
     CDS             complement(62908..63561)
                     /locus_tag="VB649_000523"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEP1669498.1"
                     /translation="MAHSIWHEKIKSFLPEHYYGRINHFLDEAYASGLVYPPRENVFK
                     ALQVTPLEETKVLILGQDPYHGPKQAQGLSFSVPEEISAPPSLINILKELADDIGPRD
                     HHDLSTWASQGVLLLNACLTVPAGQANGHAGLIWEPFTDAVIKVLNEKDSPVVFILWG
                     AYARKKKAFITNPKHHIIESPHPSPLSSYRGFFGSKPFSRTNAILEKEGMTGVDWLK"
     gene            complement(63694..64344)
                     /locus_tag="VB649_000524"
     CDS             complement(63694..64344)
                     /locus_tag="VB649_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP1669499.1"
                     /translation="MINIPLMKDSLGFVLSGLPYTLGISLLSFFTGLFLGLGLSLLGR
                     SRQPLIHYLVRAYISIMRGVPMIVVLFVLYFGLPYYGLELPALLCAYLGFSMVSAAYI
                     SEVFRSSIEAIDKGQWEAAKALGLPYALMVKKIILPQAFRIAVPPLGNVIIDMVKSSS
                     LAAMITVPDIFQNAKIIGGREWDYMSMYILVAFIYWLIAFLLERYQEFLENKLALV"
     gene            complement(64373..65236)
                     /locus_tag="VB649_000525"
     CDS             complement(64373..65236)
                     /locus_tag="VB649_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEP1669500.1"
                     /translation="MKKSVTLLSIGLASLLLAACAPHQSQKSSWDTIKEKGVLKVATP
                     GTYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLN
                     NFDITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMK
                     VAQKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMS
                     DVQYNPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDK
                     KIPVIDTKDVN"
     gene            complement(65354..66808)
                     /locus_tag="VB649_000526"
     CDS             complement(65354..66808)
                     /locus_tag="VB649_000526"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEP1669501.1"
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSE
                     RFEAALEEAKQRDFSGKPFAGVPIFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVK
                     RLEALGFIILGRSNTPEFGFKNISDSSLHEPVNLPKDNTRNAGGSSGGAAALVSSGIS
                     ALATASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTR
                     NLLYYLQMEQMESPFPLATLTKDSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQA
                     VTWLREQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMET
                     MTWAIYQSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVP
                     DSKLMANLAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEG
                     LPMGIQLIAAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            complement(67005..67634)
                     /locus_tag="VB649_000527"
     CDS             complement(67005..67634)
                     /locus_tag="VB649_000527"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEP1669502.1"
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLS
                     YPKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDH
                     GAGNQIEGRALKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKAS
                     QNFKEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            complement(67692..68384)
                     /gene="pyrF"
                     /locus_tag="VB649_000528"
     CDS             complement(67692..68384)
                     /gene="pyrF"
                     /locus_tag="VB649_000528"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEP1669503.1"
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQG
                     PDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAARE
                     GLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEV
                     EAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPV
                     AAYQAIKAEWAG"
     gene            complement(68661..69197)
                     /locus_tag="VB649_000529"
     CDS             complement(68661..69197)
                     /locus_tag="VB649_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669504.1"
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEF
                     PAHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLI
                     DLCQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEE
                     EAFIKYYQSPKIPTGEFE"
     gene            69419..70324
                     /locus_tag="VB649_000530"
     CDS             69419..70324
                     /locus_tag="VB649_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP1669505.1"
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMG
                     ITIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFV
                     VNAFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDD
                     NHLTASPLFKAQPHIFVSKSNPLATKSLLSMDDLSDFPYLSYDQGIHNSFYFSEEMMS
                     QMPHNKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFI
                     KHEKANLSKMGERFIEYLLEEVTFD"
     gene            complement(70404..71192)
                     /locus_tag="VB649_000531"
     CDS             complement(70404..71192)
                     /locus_tag="VB649_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEP1669506.1"
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERR
                     ELNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRS
                     VSPILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDHEVFKAYLSQKQSR
                     NVTTKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELHRTTHFSS
                     QAFLENIITLATFSGVIYRREPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(71185..71898)
                     /gene="deoD"
                     /locus_tag="VB649_000532"
     CDS             complement(71185..71898)
                     /gene="deoD"
                     /locus_tag="VB649_000532"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEP1669507.1"
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRE
                     LVLAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFY
                     TNMPERNMALGKLGVKAIEMEAAALYYLAAQHHVKALGIMTISDNLNDPTEDTTAEER
                     QTTFTDMMKVGLETLIAND"
     gene            complement(72483..73292)
                     /locus_tag="VB649_000533"
     CDS             complement(72483..73292)
                     /locus_tag="VB649_000533"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEP1669508.1"
                     /translation="MSLMTKINETKDFLVAKGIEAPEFGLILGSGLGELAEEVENPVV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKA
                     LGCEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTK
                     VYRNKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTQHIKEDFKGLVKAILAEL"
     gene            complement(73276..73716)
                     /gene="arsC"
                     /locus_tag="VB649_000534"
     CDS             complement(73276..73716)
                     /gene="arsC"
                     /locus_tag="VB649_000534"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HEP1669509.1"
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETL
                     IELLQSMGISARELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKG
                     VKLCRPSETLLDILPVPLPSPYIKEDGESVNPIEVKGEKDVIDD"
     gene            complement(73735..74946)
                     /locus_tag="VB649_000535"
     CDS             complement(73735..74946)
                     /locus_tag="VB649_000535"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEP1669510.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLSVPNMAKIGLGNISRPIPLKTVPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSVDPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRHDYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIIANMKKDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTA
                     MIGESFLGHLK"
     gene            complement(75023..75706)
                     /gene="rpiA"
                     /locus_tag="VB649_000536"
     CDS             complement(75023..75706)
                     /gene="rpiA"
                     /locus_tag="VB649_000536"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEP1669511.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQE
                     GLQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMK
                     GDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGV
                     TVLEAPKAS"
     gene            76084..78183
                     /locus_tag="VB649_000537"
     CDS             76084..78183
                     /locus_tag="VB649_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEP1669512.1"
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPE
                     EFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEI
                     QDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
                     EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKP
                     ALSRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQ
                     HHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEI
                     AKQKERQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTG
                     IPVSNMGTNDLERLKGISSRLKSHVIGQDKAVAAVARAIRRNRAGFDDGKRPIGSFLF
                     VGPTGVGKTELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNN
                     TLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATS
                     NAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKESLEEIVDLMLAEVN
                     QTTAKKGISLTITDDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKK
                     LQAILKEGQLVIRQNDQ"
     gene            complement(78241..78984)
                     /locus_tag="VB649_000538"
     CDS             complement(78241..78984)
                     /locus_tag="VB649_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669513.1"
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSS
                     IEGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQV
                     ERDIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFE
                     KLASQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFD
                     YTRFGKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(79132..79731)
                     /locus_tag="VB649_000539"
     CDS             complement(79132..79731)
                     /locus_tag="VB649_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEP1669514.1"
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMI
                     EEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNK
                     HESVVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            complement(79741..80970)
                     /gene="clpX"
                     /locus_tag="VB649_000540"
     CDS             complement(79741..80970)
                     /gene="clpX"
                     /locus_tag="VB649_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEP1669515.1"
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKID
                     DNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQA
                     LLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVR
                     ITKAAVEGKSKPVLETA"
     gene            complement(81100..81270)
                     /locus_tag="VB649_000541"
     CDS             complement(81100..81270)
                     /locus_tag="VB649_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669516.1"
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLASLFLLNAFTNL
                     VNSIHAFYGTLF"
     gene            complement(81290..81787)
                     /locus_tag="VB649_000542"
     CDS             complement(81290..81787)
                     /locus_tag="VB649_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEP1669517.1"
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAIL
                     MGRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGG
                     NKVLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQESQTFYARDAKNPYDFTVT
                     ALKHK"
     gene            complement(81867..82706)
                     /locus_tag="VB649_000543"
     CDS             complement(81867..82706)
                     /locus_tag="VB649_000543"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEP1669518.1"
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAF
                     AEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQT
                     RTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMF
                     DVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNL
                     HIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFD
                     LAI"
     gene            82915..84090
                     /locus_tag="VB649_000544"
     CDS             82915..84090
                     /locus_tag="VB649_000544"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEP1669519.1"
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSV
                     APITEDIITLAASAADQILTDEDRAKIDMVILATESSTDQSKASAIYVHHLVGIQPFA
                     RSFEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIAL
                     LVTANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQK
                     RENLQLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLIEAFQASITYSKQIGN
                     IYTGSLYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQT
                     LLDQRTRLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN"
     gene            84077..85354
                     /locus_tag="VB649_000545"
     CDS             84077..85354
                     /locus_tag="VB649_000545"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEP1669520.1"
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLP
                     IQTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSG
                     GFKAQTLNRQMIGQIVLYDIDKIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTI
                     HLEEKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESL
                     VTTSCEIPVRLLDRDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIAT
                     GNDWRAIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPT
                     VSIAHDLLNQPNAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGA
                     TQDEIAPLVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(85583..86572)
                     /locus_tag="VB649_000546"
     CDS             complement(85583..86572)
                     /locus_tag="VB649_000546"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEP1669521.1"
                     /translation="MTNRKDDHIKYSLKYQSPYNAFDDIELIHHSLPSYDLSDIDLST
                     HFAGQDFDFPFYINAMTGGSQKSKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSY
                     RLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTW
                     KKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRG
                     GDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTV
                     LELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(86559..87572)
                     /locus_tag="VB649_000547"
     CDS             complement(86559..87572)
                     /locus_tag="VB649_000547"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEP1669522.1"
                     /translation="MSNYCVQTGGKLYLTGEYAILTPGQKALIHFIPLMMTAEISPAA
                     HIQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIITGKMERDGK
                     KFGIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQT
                     LVAYTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQM
                     IQQVTASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHPAIYHPKL
                     VTLVAACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGEN
                     DQP"
     gene            complement(87565..88509)
                     /gene="mvaD"
                     /locus_tag="VB649_000548"
     CDS             complement(87565..88509)
                     /gene="mvaD"
                     /locus_tag="VB649_000548"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEP1669523.1"
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFT
                     TTSVSFLPDTVTSDQFYINGVLQNDEEHTKISAIIDQFRQPGQAFVKMETQNNMPTAA
                     GLSSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAI
                     YKVETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLK
                     TNNFEKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMD
                     AGPNVKVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            complement(88491..89369)
                     /gene="mvk"
                     /locus_tag="VB649_000549"
     CDS             complement(88491..89369)
                     /gene="mvk"
                     /locus_tag="VB649_000549"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEP1669524.1"
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFP
                     ADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRA
                     VFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIAL
                     NGYLIIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQL
                     MTQAHSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKIS
                     HRLKEEGAVNTWIQML"
     gene            complement(89663..90895)
                     /locus_tag="VB649_000550"
     CDS             complement(89663..90895)
                     /locus_tag="VB649_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEP1669525.1"
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRIL
                     HLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDR
                     EEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLA
                     VSMMLAFGGFIFFVILVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNE
                     LVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAED
                     FKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIG
                     RRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFK
                     GTITVNYKNDAIVFTVVI"
     gene            complement(90904..91572)
                     /locus_tag="VB649_000551"
     CDS             complement(90904..91572)
                     /locus_tag="VB649_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1669526.1"
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNA
                     YDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKP
                     FSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFL
                     MLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYC
                     LLEK"
     gene            complement(91575..92225)
                     /locus_tag="VB649_000552"
     CDS             complement(91575..92225)
                     /locus_tag="VB649_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEP1669527.1"
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETG
                     FKLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVD
                     LLKSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTI
                     AQDSWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTEEE"
BASE COUNT        27982 a        19415 c        16285 g        28588 t
ORIGIN      
        1 tatggctgat aaatttcttt gaatttctcc ttgattattt gttataaaag ttataaaata
       61 atcttgttgg aaccattcaa aacagcgtag caagttaaaa taaggctagt ccgttatcaa
      121 cttgaaaaag tggcaccgag tcggtgcttt ttttgatact tctattctac tctgactgca
      181 aactaaaaaa caagcgcttt caaaacgctt gttttatcat ttttagggaa attaatctct
      241 taatcctttt atcattctac atttaggcgc tgccatcttg ctaaacctac taagctccac
      301 aggatgattt cgtaaactat cataaagaaa aggaaacagt gcaagaaaaa gacttctgga
      361 aggatccaaa tcacaggatc tttcaaggga tcaaaaagcc agctgctatc tcctacaaaa
      421 agcacctgat gaaaaagagt aaaaaaatgt tcaaacccaa tgaaactagc cattagacca
      481 atcataagag gaaacaaagc tgctagtatt aaaggttttt gaaggagcca gaaacgtttg
      541 gtttgtaacc tttgtgtgaa agtcttaagg gttgggtaaa ggaggccaag aaaaacgact
      601 tgagttaggt gaaaaagcca cttcacatct gcaaaatgct tgagtccgtc tgctgatgag
      661 tgaaaattag caaattccaa ccttgttaca aaaggattgg taaggtaatt tagtagtccg
      721 ttatagttat gcaagatagc atccttgctc ataaaaacaa cttgttctaa ctttagatgg
      781 tccacctcaa gaggatacca cagccacgtt gaatagatcg ttatgagaat agctaatgct
      841 aataaccata cccagctaca tagtaattta gtgttttcta ccatcacaac ctccactcat
      901 caagactaga taggacatga tctggctgaa ttggtaaggt tggtacctct tcaggtctgg
      961 taaagcctgt tgtcacgagg atcgttgcaa tatcattttg aatacctgcc atgatatcag
     1021 tcaagtaatt atcgccaacc atgacggctt cagagcgctg aatgcccaat acctctagtg
     1081 atttattcat aatgatagcg ttgggcttgc caataaaaac aggttttaca cgtgtggcag
     1141 cttctagtaa ggcattcaat gcacctgctc ctggcatcaa accacgttca gtcgggatgt
     1201 ttaaatcagg atttgtccca ataaagaggg cacctttttg aatagccaag gtggctatag
     1261 ccaacatctc ataggtcatc tgactgtcta aaccaaccac cacgtaagcg ggattctcaa
     1321 gttcttctac gtaacctgct gctgcaatag ctgatttgag ccctgtttct ccaataacgt
     1381 aagctgtctt gccacggttc atgtcattca tgtaatcgac ggttgccatg gtagccgtat
     1441 aaatggtctc aatgcttgtc tcaacatgaa actgattagc cagcatgctt tgcaccattt
     1501 cgggtgttct tgtggtatta ttagtcacta ataaataggg aatgcctctt tcttgtaggc
     1561 gtttgataaa ccgctcccct gctggaatac ggtttttccc ttggtaaatc gttccgtcta
     1621 aatcaattaa ataaccctta taaggcacta gtctgtctcg ctttctgttt gtttaatcgc
     1681 tcgccattca atcatggctt gggcattcag ctgcccatct gaggtgattt gatggtaaga
     1741 agttaattgg tccaaatggt aactggaagt aatttgaccg cctggtgaga cttctttaac
     1801 atatttcaaa gtcatcttaa gaggctgatg cgtttttaaa aactcacacc ccaacacatc
     1861 atacatccaa tctaaatatt tactgttgtt gacatgacca ttcatatcaa tatcaaaata
     1921 acgcacataa taatcacgat caattgattg ttctaaaaga ggcattttag gaacacggtg
     1981 tagcttttta acaaaatcag tctcaaatgg cgctactaaa tcttctggaa tagttgccac
     2041 ttttcgcgta tctgggttta acaaagcaaa ataggctaag atatccacta aaagaccccc
     2101 ctcttgatca taaatataaa attggcgata acaaaaaaat ttattatagg aaagggcttt
     2161 tgtttcaatg gtgatggttt cttgaaaatg tggcaagcga tgaatagtga tctcataatc
     2221 cgttacaatc caaacaagct tgtaatcaac taaaagattg ttgttacttc gtcctaattg
     2281 cgcagactgt ctaccagaaa ccatcaaaca atagtctaat aaaaggggca attttatatc
     2341 tgatttgaca tcacataatt caaaaggaag tgtcaactcc tcctgataac ttaatcccat
     2401 aatactctcc taatctaata taaaccgctc agcaacagaa tcacctaaga aaagaccctt
     2461 tttagtcatt ctgacaaagg cgtcatcttt gacaagcagt ccttggtttt gaagctccct
     2521 aacaatattt ccataacgct cctcaaaaga cataccaaat ttttcttgga accgctggat
     2581 ggagactcct gtctttttac gtaagcccaa aaagagttcc tcttccatca tttcctcttt
     2641 gcgcagcact tcttcattta gtctagcgtt tcctgcttca accgctttaa gataatgctg
     2701 gatgggcacc cgattttgat aacgaatgcc attaaggtaa cctgaagccc ctgcaccaca
     2761 tccaaaatac tccacattat cccaatacat caagttatga cgactttcaa aaccaggttt
     2821 ggtaaaattg gaaatttcat aatgctcaaa accattagct tccatttctg aaataatata
     2881 ctcaaacatt tctgcttcca agtcttccgt tggtaagtta agtttaccac gtcgcatttt
     2941 gttcataaaa acggtgtgat gttccaaaat aaggctataa agactaaggt ggggaatatc
     3001 aagtgccaaa gctttagcaa cattttcctt gacttgatct aaggtttgac ctggcaaggc
     3061 ataaattaaa tcaatggaaa tattgtgaaa gcctgcagct tttaaattag cgatggtgct
     3121 ataaatttgt tcttcattat ggctacggcc gatctgcttt aattgcttat tattaaaggt
     3181 ttgcaccccc aaggaaatcc gattgacagc tgacctctga agcaccgcaa ttttttctgg
     3241 cgtcaaatca ccaggatttg cctcaattgt gaattcttca agatcatcta aattgaggtt
     3301 tcgttcaagg tgatttagga gatactccaa ctgtttagca gtgatagctg taggagtacc
     3361 tcctccaata taaagggttt ttaggtttcg aatgccataa gagtcaaatt cttgaatcaa
     3421 ggctttcaaa taagcatcaa caggttgatt ttggataaag acttttgaaa aatcgcaata
     3481 ataacaaatt tgtgtgcaaa aaggaatgtg cacataggct gaagtaggtt tttttgacat
     3541 ggtcttatta taccactttg atgataaaat gtttctatga ataaaccatt tcccttgatt
     3601 cttcatggct tggaaaaata ttttacgagc tgacaaacgt cagaatcatt ttcgtttcct
     3661 ggcttgcaac ccttagctag caaaacaaat ccttgttctt ggtaaaaaag cttgcttgat
     3721 tcttgactga ccataatgct taaagaaggg agtttctctt gcatatctgc cagaagatat
     3781 gtctggacag cctccacaat agctgctgga acctcgtttt ctgtcactgt ttcaagaatc
     3841 cctaaagtca tttctagaaa ttcccccttt tcttgaagaa tcacaaaggc tactcttgct
     3901 ccatttcgaa gcacttgaaa aagcgtctga tcctcgttaa cagcagccgc aaacacttga
     3961 ttagctgcaa ctgtcgataa caaatgataa gctaggcttt tatctgctag caattgctct
     4021 gctgtttttc ttgtcacagg catcacataa aaagatgggg tatctagtaa tcgttcaaaa
     4081 tttttagtta actgcttgat gcggcgcttt tgaatatctt ctttttgggt ttgataaaca
     4141 tatgaagcat aaccttcctg aaattcagga atcatatcta agtaaagtgt ggctgcaaaa
     4201 ggaggcagta agtccgctag tttttcgatt tgctgttttg tcatccgata tcctttctct
     4261 tctactttag caatttataa aagagacttg ggctaaacgc cccaagcctc tttccaattg
     4321 ttgacagaag ccttggaaat aaggtttctt gtttgtactc aactcgttag ttatcgcatc
     4381 cgatttctgt acggacgaca tcagcaatag tatcgacata ataatcaact tcggcatctg
     4441 ttggcgcctc tgccatgaca cgaagaagag gttctgtacc acttggtctc acgagaatac
     4501 gaccattacc agccatttca tcctccattt ttgcaatgat gttcgcaata gctggaactt
     4561 ccatagcacg ttctttcatg ctgttttcca cacgaatatt caccagtttt tgagggtaaa
     4621 tggttacttc agcagctaat tccgaaagtg atttcccagt ttccttcatc accttggcta
     4681 attggatagc tgtcaactga ccatctccag tggtattgta gtccatgata atgacatggc
     4741 ctgattgttc accaccgaga ttgtatcctg agctacgcat ttcttcaacc acatagcggt
     4801 ctccaactgc tgtaattgct ttattaatac cttgtttatc taaagcttta tgaaaaccga
     4861 ggttagacat caccgttgtg acaatggtat tgtgagcaag aagccctttt tctgacaagt
     4921 atttaccaat gataaacata atacgatcac cgtcaacaat ctcaccagtt tcgtccacgg
     4981 caatcagacg gtcgctatcg ccatcaaagg ctaaaccaag atctgctcct gtttccttaa
     5041 ctaactcttg aagttgttct ggatgcgttg aaccaacacc gtcattaata ttaaaaccat
     5101 ttggtttttc gccaatgaca gcaatttctg catttaaatc taaaaagaca tcacgtgctg
     5161 acactgaagc agctccatta gcagtgtcta aggcaactgt cataccgctt aagtcagtac
     5221 ctgttgttac caagaacttt tcatatttac gaagtccttc tggataatct accaaggttc
     5281 caagtccttc tgcactcggg cgaggaagcg tgtcctccgg agcatctaag agagcttcaa
     5341 tttccaattc ttggtcatca gctaacttaa acccatcatt cccaaagaat ttgatgccat
     5401 tgtcaagcgc agggttatga cttgcagaaa tcatcacacc tgcacttgct ttttctgttc
     5461 taactaaata agagacacca ggtgtcgcta aaacgccaag tttataaact tcaataccaa
     5521 cagatagtag accagcaatc aaggctgact ccaacatttc tcctgaaata cgggtgtcac
     5581 gcgccacaaa aactttaggt ctttcggtct catgttgact taaaacataa ccaccgaatc
     5641 ggcccagttt aaaagctaac tcaggtgtca gctcaacatt tgcttcgcca cgaacaccat
     5701 ctgttccaaa atattttccc ataatttata taagcctaat ggcttcctcc attcaatttt
     5761 cctagttatt atccattatt ttttggtggt tgtcaactga acggtcacta ctgacggctc
     5821 aattgacacc tgactagaag acaaactcac ggtcttacta gtatttttag tgacatcaga
     5881 aatgttaact tctgcaataa tttcatcaat atcttctaag acctctcgac tacctgagat
     5941 aacagctgtt tgttttgaca atttgtattg aatatctgat aagctatcat ccatcatccc
     6001 cactgcctca actctaatcg ggactgattt cgttattttt tttacagcaa ctgataaatt
     6061 tgtttttgca ggatcaattg cacttgctaa aatagttcca tcagctgaga cagcttgtaa
     6121 ggtcactcga ctactataat tcctatctaa catttgatca tcaggtaact ttgccacaac
     6181 gtgatcaatt aaagcaatgg tagattcatc actggtcact tcaaccttat caacccccgt
     6241 ttcaattttg ctaatttcat aaccatttgc aatttgttta gcatcaacgc ttcctctaac
     6301 aggaaatacc ttagattctt ttttgccaat tgtgactgat attttatctg gagatacggt
     6361 agctgtcacc ccagaaggga ggttttctac tcttaggttg acatttactg tacctggatg
     6421 actatgtgtt agatccgcca caatcttaaa attacgtgta tcattgttca cttcagaatc
     6481 taatttgata cgattagtgg aggttagata aacttccgca ccataagaat acccactgat
     6541 aaaatatttg tcactatcat acttcatatc aattggtaca tctttaaggc tatgcgtata
     6601 ggtttcaatc gggctataaa tttgcgagct agagttatta tgattgctcg atgctgcagt
     6661 taaaaaaagg agaatcgcaa aaaagactga taccattcct aaccaaggac gactatttaa
     6721 aaatcgtttc atttagattt ccctcctaga attttcttat accatggtaa actaacattt
     6781 gaatcactca tcaggtaggt cctaagtacc gtttcaaatt catctgtgct taaatcgtgt
     6841 aaaaattggc ctttgcgagt tactgaaata gctcctgttt cttctgaaac aatgatagtt
     6901 agtgcatcag agttttcaga taatccaata gccgctctat gacgggtccc aaattctttg
     6961 gaaattgcct ttgattctga caaaggcaag taagcacagg ctgccacaat cttattctga
     7021 ccaacgataa cagctccatc atgaagcggc gtattcggaa taaaaatatt gatgagtagt
     7081 tgacttgaaa tatcggcatt cagcggaatt cctgtcgcaa tatattcttg taaggtttga
     7141 gtctgttcaa taacaatcag tgcacctatc ttgcgtggac ccatataggc cacagattta
     7201 atcaaagcat cgaccaaagc agattcactg ctgacgtact gtttttgtaa aaaaacttgc
     7261 gtagaacgac caaatttctc cagtcctgcc cgaatttcag gggtaaaaat gactactcct
     7321 gcaattacac cataagtaat gacttggttc attaagtatg tgattgtcgt aaagccaatc
     7381 cactctgcaa taaaacgaag aaccaaaaag aaaatgaccc cttgaactaa agacatgatt
     7441 ttagttccag tcaatgcttt aataaaacga taaatcaaat aggcaacaat tagaatatct
     7501 aaaagatgca ctgccagcag ccaaggatcc gcaaataagc ttaataaaaa tttaatatcg
     7561 atactagata aattattcat acaactctca tttctatatc aaaaaagtta ttagctatat
     7621 tatatcatat catgatcaaa gatttttccc tatctaaaat caataaactt atgataaaat
     7681 ataagcatga aaatgaagac attactcggc attattgctg gcaaagctgc tcaatccatt
     7741 ttaacaaaac tagggcgagg atctacttat cctggtcgat tggctctagc ttgtaataaa
     7801 gatattttaa aggatttgtc taaagactat gatattgtgg tcgtcactgg tactaatggt
     7861 aaaacgttaa caactgctct tactgtcggt attttgaaag aggcatttgg cgagataatc
     7921 acaaatccaa gtggtgccaa tatgattact ggaattactt ctactttttt agctgctaaa
     7981 aaagggaaat ctgaaaggca aattgctgtt ttagaaattg acgaggctag tcttcctaga
     8041 attaccactt acttaaaacc tagtcttttt gtttatacta atatttttag ggatcagatg
     8101 gaccgctacg gagagattta cactacttat cagatgattg tagatggtgc tcgaaatgct
     8161 ccaaaagcaa ctattctagc caatggagat agtcctattt tctcttctaa ggacatagtt
     8221 aatccagttc agtattatgg ttttgatact gctaagcatg ctccgcagct agctcattac
     8281 aacacagaag ggattttatg tccaaaatgc gaacatattc ttcagtatcg tctcaatact
     8341 tatgcgaatc taggagactt tgtttgctta aactgtcagt tccaaagacc aacgttagat
     8401 tatcaattaa ctgagctcac cgctattact caccaaagtt ctgaatttgt tattgatgga
     8461 caaaactaca agataaatgt tggtggtctt tataatattt acaatgcgct tgctgccgtc
     8521 tctgttgctg aatttttcgg tgtttctccc gagaaaatca aggcgggctt taacaaaagt
     8581 aaggcggttt ttggaagaca agaaactttt actattggtg ataaatcatg cacccttatc
     8641 cttatcaaga atcctgttgg agccagtcaa gcgcttgaaa tgattcagct agctgattac
     8701 ccatttagct tatctgtgct tttaaatgct aattatgctg acggcattga taccagctgg
     8761 atttgggatg ctaattttga actcattacc caaatgccca ttacagaaat taatgctggc
     8821 ggcgtccgtc actctgaaat tgctagaaga cttagagtca caggatttga cgatactaaa
     8881 ataaagcaag ctgaaaagct cgagcaaatt atagaaacta ttgaaaaaca agaagctaag
     8941 catgcctata ttttagcaac ctatacagca atgttagaat tccgtagcct acttgctgac
     9001 cgccatgtcg ttgaaaagga gatgatctaa tgacatacac ttcactaaaa tctcccgaaa
     9061 atcaagacta catctacgac ctcaatatcg cccatctcta tggtaatctt atgaatactt
     9121 atggtgataa cggcaatatt ttaatgctca agtatgtcgc tgaaaaactt ggagctaggg
     9181 ttactgttga tattgtatct atcaatgata cctttgaaca agacgattac gatattgttt
     9241 tctttggtgg tggtcaagat tatgaacaaa gcattgttgc caaggatttg cctagcaaaa
     9301 aagctgcctt agcagattac attgctaata ataaagtggt gcttgccatc tgtggtggct
     9361 tccaattact agggcaatac tatgtccaag ctaatggggt taaaattgat ggacttggaa
     9421 ttatgggaca ctacaccctt aatcagcacc aaaatcgctt tattggagat attaaaattc
     9481 ataatgacga atttaacgaa acctattatg gctttgaaaa tcatcaagga cgtaccttct
     9541 tatctggtga cgaaaagcca cttggacgag tggtttatgg caacggtaat aataaagaag
     9601 accaaactga aggtgttcac tataaaaacg tctatggtag ttatttccac ggtcctatct
     9661 tatcacgaaa tgttaatctt gcttaccgct tagtaacaac agctcttaaa aaaaagtatg
     9721 gatcagctat ttcactacct agctatgatg atatactgaa acaagaaatc actgaagaat
     9781 atgccgacct taaaagcaaa gcttccttta ataaagttta agttcttctt tcatgtcatc
     9841 aaacaaaaac tcctaagcag gacacgatag ttcgcttagg agttttatag ttttttcttc
     9901 tgacagagct tcttaagtga ttaaaaccac taagaaacaa tagctttagc aacttcttca
     9961 acggtcatgc gtgagaagta ctgggtcgta tcaatcgttt ttaaacgttc aaaaacatca
    10021 cggtactcat atttacaacc aattaataag ttctcaatgt cttgcacatc tttgattcca
    10081 aagaaatcac catagatttt aaggttttta atgatagaat tttcaacatt tgcaaaggtt
    10141 gaaattttac ctgcagggta acgaacattg cgttcaatcg tatattctgg cgctttgccg
    10201 taggtccaat cccagctacc aaattgctct ttggcagatt gttcaatctt agccaactca
    10261 tcctctgaca agacatattc tgtcatgtct gggtacgttt ctttcatctt ggtcaagatt
    10321 ttatctgaaa attcctcaac ggtaattttt tctggtaatt catttaaaat attggtcaca
    10381 cgggcacgaa cagacttcac tcctttagac tcaatcttat ccttacttac cttaagagca
    10441 tcgccaagaa cggtcatatc cacatcaaac aaaaggcaac catggtgcat catgcgacct
    10501 ttgtagtaag cttgagcatt accacagatt tttttgccat caatttcaat atcattacgg
    10561 cctgtaaagt tggctgttac acccaagtca gctaaagtcg caatcacagg ttgtgagaag
    10621 gttttgaaat caaatgcgcc ttccgctgtt ttatttgaaa tgatagtgta gttcaagtta
    10681 ttcaaatcat gataaaccgc accaccacca gataaacgtc gcacaacatg aataccatgt
    10741 tcatcaatgt attctttatt gatttcttga atggcatttt gatgtttgcc aataataata
    10801 gctggctcat tgatccaaag gataaacaat tcgtcttctt ccactagttc tctaaaagca
    10861 taggcttcca aagcgatgtt aaaggcagga ttgtgacttt tgttaacgat gtatttcata
    10921 ggagaaaaaa tcctttcaaa aatgtaatct acctctctag tataatgaaa acaaatataa
    10981 aagacaagtg tcctattctg tatgacatct tcagtaccta cacttattag tgcacaaaaa
    11041 ctcagccatt atttatgtaa ggatttataa aaatacttta acgtggtata tttttactta
    11101 gtaaaccaat ctacttttat tatctcattt ttatattgga ggaatttatc agtgaatact
    11161 tatttttgca cacaccataa acaattacta ctttattcaa acctattcct tagctttgct
    11221 atgatgggcc aaggaactgc catttatgcc gatacactga cttcaaattc agaacctaat
    11281 aatacttact ttcaaacgca aacgcccact actacagata gcgaaaaaaa agtagtacag
    11341 ccacaacaaa aagactacta tactgaattg ttagaccaat ggaacagtat tatcgcaggc
    11401 aacgatgctt atgataaaac caatcctgac atggtcactt ttcataataa agctgaaaag
    11461 aatgctcaaa acattattaa aagctatcaa gggcctgacc acgaaaatag aacttacctt
    11521 tgggaacatg caaaggatta ttccgcttct gctaatatca cgaaaactta ccgcaatatt
    11581 gaaaaaatag caaaacagat cactaatcct gaatcatgct attatcaaga tagtaaagct
    11641 attgctattg taaaagacgg tatggccttc atgtatgaac acgcttataa tctagatcgt
    11701 gaaaatcatc aaacaactgg aaaagaaaac aaagaaaatt ggtgggttta tgaaattgga
    11761 actcctcgtg ctattaataa taccttatcc ttgatgtatc cttattttac tcaagaagaa
    11821 attcttaaat acacagctcc aatcgaaaaa tttgtgcctg accctactcg ttttagggtt
    11881 cgcgctgcca atttttcacc ttttgaagcc aatagcggaa atttaattga tatggggcgt
    11941 gttaaactca tttccggtat tcttcgtaaa gatgatctcg aaattagtga tacaatcaaa
    12001 gcaattgaga aagttttcac gctagttgac gaaggaaatg gtttttacca agacggttct
    12061 ttaattgatc acgtggttac taacgctcaa agtccacttt ataaaaaagg cattgcttac
    12121 actggagctt acggtaatgt gcttatagat ggcttatcgc aattaattcc tattattcaa
    12181 aaaacaaagt ctcctataga agcggataaa atggctacta tctatcattg gattaaccat
    12241 tcttttttcc ctatcatcgt tcgtggagaa atgatggata tgactcgagg gcgttctatc
    12301 agtcgtttta atgcccaatc tcatgttgct ggcattgaag cacttcgtgc tattttacgt
    12361 attgctgaca tgtctgaaga gcctcaccgt ttggcactta aaacacgtat aaaaacactc
    12421 gtcacacaag ggaatgcttt ttacaatgtc tatgataatt tgaaaaccta tcacgatatc
    12481 aaacttatga aagaactact aagtgatact tttgttccag tccaaaaact tgatagttac
    12541 gtagctagtt tcaatagtat ggataaattg gcactatata ataataaaca cgattttgct
    12601 tttggcctat caatgttttc gaatcgaact caaaattatg aagctatgaa taatgaaaat
    12661 cttcatggct ggtttacttc tgatggaatg ttttacctat acaataacga tttaggacac
    12721 tacagtgaaa actattgggc aacggtaaat ccctaccgct tacctggaac cacagaaact
    12781 gagcaaaaac cactagaggg aactcctgag aatattaaaa cgaactatca acaagttggc
    12841 atgactagtc tctctgatga cgcttttgtt gcaagtaaaa aacttaataa cacaagtgct
    12901 ctagctgcta tgaccttcac taattggaat aaaagcctca ctctcaataa agggtggttt
    12961 atcttaggaa acaaaataat ctttgttggt agcaatatca aaaaccaatc atctcacaag
    13021 gcgtatacaa ctattgaaca acgaaaagaa aatcaaaagc acccttactg ttcttatgtt
    13081 aacaatcaac ccgttgactt gaataatcag ctagttgatt ttacaaacac taaaagtatt
    13141 ttccttgaaa gtgatgatcc cgctcaaaat attggttact acttcttcaa gccaacaaca
    13201 cttagcataa gtaaggcact tcaaacaggg aaatggcaaa acataaaagc tgatgacaaa
    13261 tcaccagaag ccatcaaaga agtttcaaat acctttatca ctatcatgca aaaccatact
    13321 caagatggcg atcgttatgc ctatatgatg cttccaaata tgactcgtca agaatttgaa
    13381 acctatatta gcaagcttga tatcgacttg ttagaaaaca atgacaaact ggccgctgtc
    13441 tacgatcatg atagtcaaca gatgcacgtc attcactatg aaaaaaaagc aacgatgttt
    13501 tcaaatcata atctttctca tcaaggcttt tatagttttc ctcatcctgt caagcaaaat
    13561 caacaataaa agcttgctca tcaaggaatt gcagctaaaa acaatgctct taactctcat
    13621 aaaattcccc acaaaagaca acgacgctta ccgcatactg ggtatcagtc ctcctcttta
    13681 gaattcttag gtggagcttt agttgcttct tttaaccata tcacaaaacc ctttcgtaag
    13741 aaagacttaa ggatttagct gttattggaa agtaagggtt aacaatgaaa cgttattaaa
    13801 gacaaaaaaa ctggaaactg cactgagccc caaaagttgg ctactctatt tgaagtaaag
    13861 gatttagttc tgtattgtag aggactaagt ccttttcgtt ttattttgat acgtttattg
    13921 ttgcaataat cgatgataat agtaggtaga acgagtcaat ttagccgtcc ttaaaagaaa
    13981 atctaatcag aactcgtctt tgtccattct ttataatggt tttttgtctt cttcttttca
    14041 gagatgcttc tttcaaacgg agttccctca gtttttttag cgctaaatgt ctagcttatc
    14101 ttcatagctt aatgtcatac aaaaacaccc caaacgttag ggttttgtat ctaacgtttg
    14161 gggtgcagtt catagttgtg ctagtctttt ttgtgatctg ttatgtgatg atatttttca
    14221 ttagttaata agacaaagac gttttactta cgttttggtg ggttatggat agcttcgcca
    14281 agcacatctg caaaggcttc gtacatcact tcagagaaag ttgggtgtcc atgaattgat
    14341 aataacaatt catcaacggt taattcagat tccataatag tagctgcttc attaatcatc
    14401 tcagctgcag ctggaccaat aatgtgtaca cctagaattt cgtgatattt ggcatcagca
    14461 ataactttaa caaaaccatg ggcttcattt gaagcaatcg cgcgtccatt accagtaaag
    14521 ctgtttttac caataagcac atcaccatat tgttcacgcg cttgttcttc agttaaacca
    14581 accattgcca cttcagggtg tgtgtaaaca gctgctggag tgtatttaag gttagcttta
    14641 cgagttgtgt tgccatgcat cgcattttct gcagccactt cacccatacg gtaagcagcg
    14701 tgagcaagca ttttcgttcc gttaacgtca cctggcgcat agatacctgg aattgatgtc
    14761 tcttggtagt cattaacttt gatacggtta cgatccattt caaggttaag attttccaga
    14821 ccgttcattt gtggtacacg accgatagaa agaagagctt tttcagcgac aacttcttca
    14881 ccattgttaa gcttcaaggt caattggtta tttgcttcaa caatttcaga gacaccaaca
    14941 gatgttttga tcttcatgcc tttcttagaa aggatttttt gaagttcaag agagacttcc
    15001 ttatccatag ctgggataat gcggtcagcc atttcaataa cggtaacatc aacaccgtaa
    15061 gatgcccaaa caagtccaag ctcgatacca acaacaccac cgcccataac tgctagtgat
    15121 tttggcattt cacgaaggtc aaggatatcg tcagacatta agacaagttt agagtcaatt
    15181 cctgggatat tgatacgtga tactttagaa cctgtagcaa ggataacgtt gcgaccctta
    15241 atggtttgtg acccaatggt tacagtcttg tcagggttga cttgaccaag cccattaaag
    15301 atagtgactt tattagcttt tagaagacct tgaacaccac ctgttaaggt tttaacaacg
    15361 gtgtttttaa agtcaactgt tttgtccatg tcaatggtat agttagttga ggcaaggtta
    15421 atcccacgtc ctgctgcaat cttaatacca tcaaggattt cagcattttt aaggtaagtt
    15481 ttggttggga tacaccctac gttcaagcaa gttccaccaa attcagattt ctcaacgatg
    15541 gcaattttac caccaagttg agcaccacga atagctgcat aataacctgc agggccacca
    15601 ccaacaacga tgatgtcata ctcatcatca gcaagtgcag cttttggtgc agctgaagca
    15661 gcttgagctg gtgcttttgg cacttcaagt ccggcagctt ctaaatcttc tgttgtacga
    15721 gcaacattca catctgaagc agctgggcta gaaacctcaa cagattctcc ttcagcaccg
    15781 atgtaaccga taacttctgt tacaggtact gtttcacctg cttgacgtgt aattttaaga
    15841 agaacacctg agtcttctgc ttcaagttcc atattggttt tatctgacat gatttcaaga
    15901 agaatatcgc cttcattgac agtatcacct tcttgttttt tccactcgat gatttcacct
    15961 tcttgcatgt caacaccgag ttttggcata ataatttcaa cagccataat ttaagatacc
    16021 aagagcaagg agaaagcgat tgaatttttg cagtaagtca gaaatctttg atttcgttga
    16081 cgcacccacg tcaggacgac taggactttc cgaaacaaaa attgaggaaa gttcagacgt
    16141 ctacgacgct aagattagcc aactcttacc atttttatcc gggcttttcg ctcgggttca
    16201 attgcttatc actcatttgc atgagagctc ctcgttctac atcctttcta tatttttgag
    16261 aaaagggcac caagtctaaa cttagcaaaa tcccttttat tattcaatgc ttttcttgtt
    16321 taaaactgat tgatcagatt aacaattcaa atggattttc catcaatttc ttgagatcaa
    16381 ccatgaattt tgcaccgttc ataccatcaa ctaaacggtg gtcgatggtt aggcacatcg
    16441 ccataattgg acgggcaaca atctcaccat ccacaaccgt tggagttggg atagttgctc
    16501 caacaccaag aattgctgag tttggttggt taataattgg gttaaatgtc ttcgtaccaa
    16561 acattcccaa gtttgtgata gagaaggttg atccagacat ttcagctgct ttcaacttac
    16621 cagtttgcgc ttttttaatc acatcttttg aagcaagcac aaaatctgac aagctcatct
    16681 tgtcagcccc atggataaca ggaacgataa gaccatcatc aagacctacg gcaataccaa
    16741 ggttcacaaa gcggtgcaat tcaatatcat tagcatcatt gatgagggaa gcattcatgt
    16801 actcatgctc aggtttcatc aatgttttaa ccactgccat accaatcaag tctgtgaagc
    16861 tgactttaag gcctgtttta gccatgattg ggtcaattaa cttcttacga agggcaatca
    16921 tctctgtcat gtcaatatcg tagttaagcg taaaggtagg ggcagtaagg taagagtttg
    16981 tcataccttt agagattgcc ttacgcatag ctgacattgg cttgtgttcc acaccttctg
    17041 gaagatcaac aactttttct tctttagctg ctggggcttt tgcttcagct ggtttagccg
    17101 cttcaagaat agccatgatg tcttctttca tgaccttacc gttaaagcca gtacctgata
    17161 cggttgccaa atcaatacct ttgtctgctg caattttacg agcaagtggt gaagctttcg
    17221 gttgagcacc tttaaagttt tcaacgtctt ctttatggac acgtcctttt ggtcctgttc
    17281 ctggaacttg gccaaggtca atgcccattt ctgctgctgc cttacgtgca gctggagtag
    17341 cacgaacttt tccaccattt ccttgcggaa tagctgtcgc tgccacttga ggagctggac
    17401 ttgccacatt ttcttttgga gcaactgttg gtccagcatc tgctgaagca ggaactggaa
    17461 tttctgttgt tttttcactt gaagcaatag tatctactga ttcaccctct gcaccaatgt
    17521 aaccgataac ttcagttaca ggtacagtat caccagctgg acggacaatt ttcaatagca
    17581 cacctgagtc ttctgcctca agttccatat tggttttgtc tgacatgatt tcaagaagga
    17641 tatcaccttc attgacggta tcaccttctt cttttttcca ctcgatgatc tcgccttctt
    17701 gcatgtcaac gcccagcttt ggcataataa tttcaaatgc catttctaca tcctttcacg
    17761 atttgataag cgccatcaac atccccacct tgctacgaaa acatacgaaa ggtgaggtgc
    17821 cgcgacacgg gataagacaa ctcagttctt ctaaaaactt tcaaaatagt ttttagctga
    17881 gacgttactg ataaacatag cctttatcag accacttgcc ttatcttcta gttgcctttg
    17941 tttgccattt tcacaatagc agctttgatt ttctcaacgt ctggtaagat cgcttgttca
    18001 agtacacgtg cataaggtac tggaacatct tcacttgcaa gacgaacgat tggatgatca
    18061 aggtaatcaa aggcttcact ttcggtaatc atggttgcaa tttccccaat gaatccacct
    18121 gttttgtaag catcattgac aagcatcaat ttacctgttt tcttaacaga ttcaataatc
    18181 aactctttat caagtgggat gagggtacgt gggtcaacaa cttcaacgtt aataccatcc
    18241 gctgcaactt cttcagccgc ttgaagaaca cgctccaaca tacgaccata tgacacaatt
    18301 gtcaaatcag ttccttcacg tttgatgtca cctttgccaa gtgggatata gaagtcagga
    18361 tcttggttaa cttcttcttt tttaccataa agcgcttttg gttccatgaa aagaacaatg
    18421 ttattatcac ggatagctga ttttaataag cctttagcat cgttggcatt accaggagca
    18481 acaactttga ttcctggaat gtgagtcaac catgcctcaa gagattgtga gtgttgcgca
    18541 gcggaaccaa taccagaacc tgatgccaca cggaaggtta caggggtaat aaggcctcca
    18601 ccgaacatgt aattattttt agcaccatta ttcacgatag cgtccatcat gatggtaacg
    18661 aaatccatga aggtaacgtc gacaattgga cgtagtcctg taatagctgc accaatagcc
    18721 gcaccagaga tagcagcttc tgaaattggg gtatctttaa cacgtttagg gccaaattct
    18781 tcaatcattc caacagaagt cccgaagtct cctccgtaaa cccctacgtc ttctcccata
    18841 aggaaaatgt tttcgtcctt gcgcatttcc tcagtcatag caaggttgac tgcttcacgc
    18901 aaagccatta attttgtttc tgacatcatt tttatttctc catttattat tcaaatacga
    18961 ttgcttctta ctgacaaggt gatcttagtc aacccaaacg tcttcgaagg ctactgaaag
    19021 ttctggatct ggactgtttt gtgcaaattc ataagcatcg tcaacttctt ttttgacttg
    19081 tgcttgaata gcatccaatt cgtcatcagt ggcaatgcct tcgcttgtca gataagtacg
    19141 atatttgatc attggatctt tttctttcca ctcatccact tcttctttag tacggtattt
    19201 accagcatct gcagtcgagt gaccaaacca acggtatgat tctacctcaa caatagctgg
    19261 accatttcca ccacgaacat gttcaacggc tttgcccatt gtttcataga cagccatcac
    19321 gtcattgcca tcttcacagt agaaaccagg aattccgtaa gcttctgcac gtgtgtataa
    19381 atgcggtgtg tttgtcgcat tgttaatgct catggagatt ccataacggt tattaatgat
    19441 aaagaaaata acaggaagtt tccatgttgc agccatattg acagactcgt ggaatgatcc
    19501 ttcgttagta gcaccatcgc ctgagaaagc aacagcaatg ttattagttc ctttatattg
    19561 ttgggtaagc gctgcaccta ctgcaagagc gtaaccacca ccaacgatac cattggtacc
    19621 atagtttcct ttttcaaagt cagccaagtg cattgagcca ccgcgtcctt tagaaacacc
    19681 agttgcttta cctgcaagtt cagccatcat tttgttaagg tccatatctt ttgcgattga
    19741 ttgaccatgt ccacggtgat ttgaaaaaat aatatcatcg taagtcaagt gagccactgc
    19801 accaacgtta gctgcttctt caccaacaga gaagtgagtc atcccttgta caaatccacg
    19861 acggacgagt ttgttaatac gtgaatcaaa ttcacgaata cgttccattt taaggaacat
    19921 atccaaatat tgttctttag aaactgttac cattttggcc tccatattat catattactt
    19981 tcctatgata aaactttttt tcacaatttg caaataatta aatcgctttc ttccttatct
    20041 tgtctgattt tatggaattg taatagtttg tgaagtcaca aacaaatctg tactaataaa
    20101 ttacaaaata atatataaca gttttcgttt tcaccaatct tgcttcaaaa aatgtgtcat
    20161 tttaaaacct cttttaccgc ttcaaacaag tttcaaagca ataaaaataa gcctagcaaa
    20221 aatgctaaag cttgttttta tgattctatt tgttcagcga tgctttccca ttcttccatg
    20281 agaagctgtt gttcttgatc taattggtcc cactcttctt gccatgtcat taactgaatt
    20341 gtatcattgc aagcatgcat gtcttcttga atagcaccaa tgcgctcttc aatggtttca
    20401 agtcttgctt caatctcctc atatcggcgg gtcaagcgac gacgctcttt ttgattagct
    20461 ttttgtagct gataatcagt ggcagaggct tcttttgttt cctcaactgt ctctcctgct
    20521 gctaggcggg ctagttcttc taactctgcc tttttctcaa ggtaataatc atagtcacct
    20581 aagtaaaggg ttgagccatt ttcggtaatt tccagaacct tagttgccaa acgattaatg
    20641 aaatagcggt cgtggctgac aaaaagcaag gtaccgtcaa agtcaatgag ggaattctct
    20701 agcacttctt tactgtcaat gtctaggtgg ttagtcggct cgtccagaac aagaaaatta
    20761 ttgttttcca tagataactt cgcaagaagc agacgggctt tttctccacc tgacagcatg
    20821 gccaccgatt ttttgacatc atctccagaa aagagaaaag cccctaatcg gtttctgata
    20881 tcgacttctg gcgtagttga aaaatcctgc cataattctt ccaaaactgt gttgctagac
    20941 gtcaaatgtg actgggtttg gtcatagtaa cctatttcaa cattggcacc gtattttact
    21001 tctcctttga tgaaaggaat ctgtccaata acagatttaa tcagagtgga tttaccaata
    21061 ccatttggac caacaatagc aatcgcatct aatttgtgaa cgtctaggtt aataggctca
    21121 gataaaacat gttggttata accaatagca gctttttcaa ccgtcaacac cacattgcca
    21181 gacggcttat ctgcctgaaa agtcatgtga gctgattttc tagcactagt cggtttgtct
    21241 aagcgttcta ttttttccaa ttgcttacgt ctcgcctgag cacgttttgt agttgaagcc
    21301 ctgacaatat ttttttgaac aaaatcttct aacttggcaa tttctttttg ctgtttgtca
    21361 aactgctttt cttcggctac taatttttca gcttttaaag tcataaaacg agaataattg
    21421 ccaacgtagc gatccaatcc atgaggagtt aaatccaaag tcactgttgc caccttatcc
    21481 aaaaaataac ggtcgtgact cacaatgatt agagctcctt gataattggc caagtagttc
    21541 tctaaccagg caatggtttc aatatctaag tggtttgttg gctcatcaag gaccaatagt
    21601 tctggctttt ctaaaagcat tttagccaag gccagacgag tgttttgacc ccctgacagc
    21661 tcagcgatag tcatctgcca catgctttca tcaaatttaa agccatttaa aatggcttta
    21721 atctcagctt catatgtaaa gccatcttgc tgacgaaaac gttctgctaa aagatcataa
    21781 tccatcatca gccgtgtcaa gtcctgacct gaaacggttg ccatatccat ttccatctga
    21841 cggagacgct tttcatcttg gcgtaatgct tcgaaaacct tgagcatttc ctcatatatc
    21901 gttttgtcag attcaaaacg gctattttga gccagataag acaaggttag gtctttttta
    21961 gtattaactt ctccgctcgt tggggtttct tccccaacca atagcttgag taaggttgac
    22021 ttaccagctc catttggccc cactaatgca attctgtctc tttcatcaac ttgcagtgat
    22081 atgttttgaa aaagaacatc tcctgagaaa gagcgttcta acttgtttcc ttgtaaaata
    22141 atcatacttt cattctaaca aaaaaatgcc cttttgagga cattttcagc ctagtttcca
    22201 aaagaaatcg aactcttttt aagtcgttga ttaccttctt tagcgctaac aaggaaagtg
    22261 gaatgactat taccactccc atgacgcgtc tttgcagatg gcttttgtgt taagatatca
    22321 aaaatttgca ccacttgctc agtaactatc gagatcttat tggctaaaac ggaatcactg
    22381 tgattagaat agtacatcag ccctataata ataatcgtta ctaataagat agtttgtaaa
    22441 aaccctttga taagatgcca aaacattttc actattagct taggcagcca caatatgatc
    22501 gccagtaatt gtttcatttg tcacctcatg ttgtactagg aaatggttaa gacaaccttt
    22561 cttctttttg gtagtttatc ggtaaccact ctaacaggac ttctaattgc tggttccaat
    22621 agtaccactc atgtttacca tgacctttat gataatcaat gtcaagacct tgagcctgaa
    22681 aatcagcaat agctttttca ttagtggcaa aaagaaaatc ctcatagcca caccaagcat
    22741 aaaatttggt ttttccatca ctttctgcca ccatattttt aaggtaatgc ttgtcaaggt
    22801 cagggtcatc aaactggcca aaaacgccct gccaataggc taattctccc aggtttccct
    22861 caagcaaggt ctcaggagaa aaatccaaag cgcctgaaaa cgatgccgca taagaaaacc
    22921 gattgctttt gagtgcccac ttaaaggcac catagccacc catagagagc ccagcaacaa
    22981 aggttttttc tcgtttctgg gtcatattag gaaagaaagc tgctaagacc tgcggtaact
    23041 cttgtgacaa cgcccgataa tagttaagtc cataagccgt gtctgtatac caacctaggt
    23101 ctgtcgaagg cataacgact atcaaattgg tatgccgcaa caagcgttca atagctgttc
    23161 gtttttgcca agagttttca ttgcctccca taccatgtaa caaatataaa acaggaatat
    23221 ccttatcccc ttgatctttt ttagggattt cagactggtc aggataaatc acacttacct
    23281 tacgatccat tcctaaaact accgaatggt attcaattac aatacttgcc attcattaca
    23341 ctcctttata ccaaaataat cctatcacgt aaatctactg tatttttggg tgaacagttt
    23401 cctggtttac cagttgttaa aatcaaagaa ggtaggcagt ttttgcctaa ccttcctatt
    23461 ttcactaacg aacttccatc acaaccggca gaatcgctgg gcgccttttg gtttgttcaa
    23521 ataagaattt agacaaatca tctctgacat tcccttttaa ttcgccccag tcaaaggtat
    23581 ctttttttaa gtaattgcca acagttgtat taactaattc tgcactttct cttaaaatat
    23641 catgactttt cttgacatac acaaatccac gcgtattaac tttagcctta gaaataatgc
    23701 gtttttcttt tttagaaaca gtaatagcaa caatgaaaat accatcttct gacaagactt
    23761 tacggtctcg taaaacgata ttacccacat caccgatagc attaccgtca atcatgacat
    23821 cactggcagg tacacctcct tcatggagaa aaccttcgtc attaagcacc atgatatcgc
    23881 cacgcttcag aatatgaata ttctctggaa aaataccaac ttcttcagct agctttgcat
    23941 gggcagctaa atcacgatat tctccttgta ctggaaaaag atactggggt tttaacaaat
    24001 tcatcaatag ttgcaaatca cgcccattag catggcctga aacgcgtaag ttttgagtga
    24061 ttaatttaac agaaccaccg gccttgtaaa tcaagttttc aacacgcgcc accatagctt
    24121 ctttagccgt acttggtgta gttacaatat aaacaaggtc tccttctttg atttgaacat
    24181 aacggtgacg tcccgctgcc attttttgta agctattaat tggctcaccc atacgaccag
    24241 cttcaaggat gattaattca tggtcttcga atttagacat atccttaggt ttaattaaaa
    24301 gacgctcatc cgtaatcatt aatttttcta gacgtaaagc tgttctgaca atattttctg
    24361 catctgttcc ggttaaaaca acacgacgcc catgggcagt ggcggaatca aatacttgct
    24421 gaatccgaac aagatttgag gctactgcag ctacaatgac acggccatca gcatcagaga
    24481 taacactgtc catttcttca ccaacttcag attcgctggc aatctgatcg ttgcttgtcg
    24541 cattgactga atctgataaa agagctagaa ccccttcttt cccaatctca gctaaacgta
    24601 gcaaatccgt ctgataacct tcccttgctg cttgatcaaa tttgaagtca ccggtataaa
    24661 caatgtttcc tttatctgtt ccaataacaa tacccatact ttctgggatt gaatgcgttg
    24721 ttctaaagaa cgaaactagg ccatctttaa attcaatttc agtatcactg tctaccacat
    24781 gaaaattatt aaatttctta gtgctgttat tacttttcac aaatagcttg gctaattcaa
    24841 tagtcaattc agatccaaat acaggagctg atacttcagc taacaaataa ggaagggctc
    24901 caatggcgtc agcatggcca tgactcaaga aaatcccttg tactttacct ttgttttcaa
    24961 ttacataatc taaattgggg atgactaaat ctaccccaag ttgctcattt tcagggtact
    25021 tgagccctgc gtctaaaata aacatagaat cgttaatttc taccaaatag aagttttttc
    25081 cgtattcacg gacccctccc aaggcaatca ttttaatatc agtcatgata ctcctttaaa
    25141 tattttatta ttacaaacgg tccttacaac gtaagtcgaa ttactgttat gtagctatgc
    25201 tactatcttc tatagtatat catatttgag gcgttttttc tctaaatagc cttgatactt
    25261 tcagattatt ttcagtatgg aaatcaaaaa atcactgact tattattcgt caatgattta
    25321 gatcgttgat taatcaaata gttggtaata gtcagtaatc gtcagttgtt ctttttccat
    25381 ttgatttaaa tctttaataa tgtttccatc tttcattaca atcagacgat tcccataagt
    25441 taatgcatct tccatatggt gggtaatcat caaagctgtt aagccatctt ttgtcacaaa
    25501 ctcatctgtc aattgcatta aagagtgact cgtcttaggg tcaagggcag ccgtatgctc
    25561 atctaataat aagagagctg gctttttcaa cgttgccatt aataaactta aagcctgtct
    25621 ttgtccacca gacaaaagac ctgctggtgt ttctaaatgt ttttctaggc catttcctgt
    25681 tcgtttaacc aaatcctcaa aactagctaa gtgctctgtt atttttcgag aagccaagga
    25741 gcgtttttct cctctttgac gtgcgattaa gagattttca gccactgtca tccgaggggc
    25801 tgttcccatt ttgggatctt gaaagactcg cgataggtaa agagctcttt tttctgctgg
    25861 ccaatgcgtc acatcctgac caagaatcct aatttgcccc cgtgtcaaac ttagcgttcc
    25921 tgcaattaca ttaaaaaggg ttgattttcc agctccattt cctcctaaaa tagttaaaaa
    25981 atcatgttca tagatagtta gtgtcacatt gtccaatatt gttttagcat cttcaaaacc
    26041 attatctacg tcaactgttg cattgatcaa ttcaataatt tttgtcatcg tgttaacctc
    26101 actcccttaa agaagcgctc ttttaccact ggtatcatga ggcacagtgc taaaacaaga
    26161 gcactaatta atttcaaata acttgtatta aaacctaacg taataactac tgaaattaaa
    26221 aattgataaa gaatcgagcc tattacaata gcaatcaaac gttctaaaag agtcagtcca
    26281 gttgagtata gtacttcacc aacaattatg ctcgccaaac caataacaat aactccaatc
    26341 ccttttgaga catctgcata gccatcttgt tgactcacta gagcacctga taaagctatt
    26401 aaactattag aaaccacaag tcccataact tccatccaat ccgtgttaat accaaaactc
    26461 ttagccatat ctttattgtc tcccgtagcg atataagctt gacctagatt agtgtaaagg
    26521 aaatagatca aaacgctaat aacaatcaca acagttatca gacctgttaa aaggctattt
    26581 aaatcaattg aaaaaggtaa acaatcctga atacgtttat gatcatgtaa acccaagttt
    26641 gctcttccca ttaccattag cataatggag ttacatgacg tcatcaccaa aattccagct
    26701 aaaagtgttg gcatttttcc tttcgtatat aacagccctg ttaaaaaacc tgctaaagca
    26761 cctgataaca taccaagtaa ggttgataga aatggattcc accctaagct aatagcggtg
    26821 accgcaacag ctcctcctaa aggaaaagaa ccttctgtag tcatgtcagg gaagtttaaa
    26881 atcctaaagg tcaggtagat tcctaatcct aaaactcccc atataaggcc ttgtgaaact
    26941 gatgaaataa tcatattttt cctcatattt atattagcgg gtaactctcg ccagtataaa
    27001 ccctttcttt acattaattt ttagatttgt tttatactta gttcagcacc gtggcttagt
    27061 cttttttcca atcactttaa cgaaactaag acagaaaaca aaaaaatcga gaatcatgtt
    27121 taaacttact caaaaggcaa gattttttac gtgtctaaaa tagagcattt taaaactaaa
    27181 aatgataaaa ataaccgtta catcctcaag gcgattgtct gacttggcat ccaaattcat
    27241 ctcagtgagg gtatttttta tgattttttc ttgacctttt atatcacatg tctttgtatt
    27301 aattctcaat aaaagaagct gaaggaaaat cttctttttt aatagcaata cctaattctg
    27361 ctgctacatt cttattaatt agcggttgac caatatccac aactttgaca ggaacatcta
    27421 caacacgctt tcctttgatt aattttaaca cctgattagc tgtttgaact cccaaatcgt
    27481 actgattttg agaaatagct gctaaaccac ctttttcaac cattcgatca acgctagtgt
    27541 agacaggaat ctttgcagcc ttactggttg tcatgactga tgaaaatgca cttgctatag
    27601 tattgtcttg ggggataaat accgcgtcta ctttacctaa cataactgac atcgtggcag
    27661 gaacttcgtt agtagaagga accgcgtatg aaataacttg atagcccttt ttgcgagcta
    27721 accgcctaaa ctctttaact tgagataagg aattatcctc attacttgca tataaaattc
    27781 caactgtttt gacatgtggt gtcagctttt tcattaaatc aattgtctgt ttaacaggca
    27841 ctttattaga tagaccagtt acattagctt caggttgatc caattgcatc actaatctag
    27901 atcctactgg atcagatact gctgacatga caactgggat atccttgctg gtggctgcta
    27961 agccttgcgc cgccggggtt gcgataccaa tcacgatatc acttcctgat tgcactaatt
    28021 gcctactcat tgtttggatt ttactctgat ccccctcagc attcataacc ttaatcacta
    28081 cattttgttt ttgaggcatc tgctttttga gttgatcttc aatacctcgc ttaatatcat
    28141 caagagcctc atgagtaacg aattgtaaga tgccaattgt aatgttttgt tggttagcca
    28201 agtcacggtt ttcctttgat actccttttg ataatagaga gcctatcact attacagtta
    28261 aaacaaggag ggtagctatt aaactcttgt ttttcatctg aattcctcac atttcatgtc
    28321 aatctcttta aaacgttgat gatgagaata cttctcaaaa gaaaaagcac ttagtaatga
    28381 ttactaggcg ctcttgtgaa atccaatgtc agcgcataga tatcttttta gaagtactct
    28441 aaaagtcgta tctatgccaa ttcataaaca caacttatct atgccagctt tgccaatttg
    28501 ctaagtgttg tgtttttacc atcattgact tcctttctcg tttttttaac attataacct
    28561 aaatcaaaaa aattgcaagc tctttcgtcc atatttttag tcaagtattt gtggtataat
    28621 gaagagatta gaattcagaa aggagaaacc atgtcttttg acggcttttt cttacaccat
    28681 ttaaccaacg aattaaaaga gaacttgctt tacggtcata tccaaaaggt caatcaaccc
    28741 tttgaacggg aacttgtctt aaccattcgt aaccatcgca agaattataa attgctattg
    28801 tctgcccatc ctgtttttgg acgacttcaa attacccaag cggactttca aaatcctcag
    28861 gtacctaata cctttaccat gattatgcgt aaatacctcc agggtgcagt cattgagcag
    28921 ttagaacaga ttgataatga ccgcattatc gaaatcaagg tatctaataa aaatgaaatc
    28981 ggagatgcta ttcaggcaac cctaatcatt gaaatcatgg ggaagcacag taatatcatc
    29041 ttggtggacc gtgcagaaaa taaaatcatc gaatccatta aacatgttgg cttttcacaa
    29101 aactcttacc gcaccatttt acctggctct acctacattg atcctcctaa aacagctgct
    29161 gttaatcctt ttacaattac agatgttcct ctatttgaaa tcctccaaac acaagaacta
    29221 acagttaaaa gcttgcaaca gcattttcaa ggcttagggc gagacaccgc aaaagaattg
    29281 gccgagcttc tgaccacaga caaattaaaa cggttccgtg agttttttgc tagacctact
    29341 caggcaaatc tgaccacagc ttcttttgcg cctgttcttt tctcagatag ccatgcgacg
    29401 tttgagactt tgtctgacat gcttgaccac ttttatcaag acaaggctga gcgcgaccgt
    29461 atcaatcagc aagccagtga tttgatccac cgtgtgcaaa ctgaactgga taaaaatcgc
    29521 aacaagctaa gtaaacaaga agctgagctg ctagccactg aaaatgctga gttgttccgt
    29581 caaaaaggag aattattgac cacctacctc agtctggtcc caaacaacca agactctgtg
    29641 attttagaca attattatac aggggaaaaa attgagattg ccttagacaa ggctctgaca
    29701 ccaaatcaaa atgctcaacg ttattttaaa aaataccaaa agctaaaaga agctgtcaaa
    29761 cacttatctg gattgattgc cgataccaag caaagtatta cttactttga gagcgtagac
    29821 tacaatttat ctcaagcaag tatcgacgac atcgaagata ttcgcgaaga attatatcag
    29881 gctggctttt tgaaaagtcg ccaaagagac aaacggcata aacgtaaaaa gcctgagcag
    29941 tacctggctt cagatggaaa aaccattctc atggtgggac gcaataactt gcaaaatgaa
    30001 gaactcacct ttaaaatggc taaaaaagga gaactctggt tccatgctaa ggatatccct
    30061 ggaagtcatg tcatcatcaa agacaatctt gatccaagtg acgaggttaa aactgatgct
    30121 gccgaactag ctgcttatta ttcgaaagct aggttatcaa atctcgttca ggtcgatatg
    30181 attgaagcta aaaaattaca caaacctagt ggcgccaagc caggatttgt gacttatact
    30241 ggtcaaaaaa ccttacgggt tactcctgac caagccaaaa ttctctctat gaaattatcc
    30301 tgataagcaa ctaaaaaaca gctctcctag gaaagttatt tcccctagga gaactgtttt
    30361 tttattctga ttgttggtgc ttgatatggt caagaaagtc ttgcatattc acatcatcag
    30421 gcacttgtct gaggtaagcg gtagccattt ggatagcctt gtgaaactgg ccaaactccc
    30481 ttaataaata ggcataatcc tgtaaaaact ctggattttc tgccaaatca gccgaaatct
    30541 cattataaag agccaaggca acttcttctt gttccaaggc gtggtaagcc tttgcaatgg
    30601 tccatttggt taagacatta tcaatcgtct cacgattaag agcaataacc tcctcaaaac
    30661 gctcagcatc aaaataaagg gtcactaaac gcatgagaat ctcttcgtca tcaacagcta
    30721 cttcctttgc ttgaagcagg taattttcag cattctgcct atcgtgtaat tcataagaaa
    30781 gctgcgatgc tagtaataat aattgactgt caaatgcatt tttacgtagg ccctgttgaa
    30841 ccaagcgcaa agcttctgac gtcttatgct cttcatgaag actcaaagca taaccatatt
    30901 cataacctgg ataatctgga ttgatggttt ccaactgttt aaagtaaaga ttggcttttt
    30961 gataattttc ttggtcatac aagagggttg ccaattcaaa aacagtttca tcttcgtatt
    31021 caatggccac ggccttttcc aagaattcga tggctgcctc aaatttccct aagctagcat
    31081 aggctcgtcc aatgcgttga taagtggaaa tacctgtcaa ttcaaggatt tgacgattgt
    31141 ctaactgtgc atagtaatca atagcttctt taaaatactg caaggacatg tcaatttctg
    31201 ccaaaccaaa aatgaccaat ggctctgagc tgatggccac tgcttgaagt aatttttcac
    31261 gcgccacctc tgtcagtcct tccatgtcat agaggtcagc cattactaag agagctgaca
    31321 aataattggg gctatctttt gaaaccttat ccaaatacaa gaaagcttct tcaatggcgt
    31381 cgtcttctgc tgcaatctga gctaaattta tattgagttc tgggtaatca tcagctaact
    31441 gcaaataaat acgcttggca tgtggcaaaa aacctatact ttctaagtat tctcctaagg
    31501 cgattaaact atctgcatca tcttctttta aagctttttg gaaatatttt tcagcgtgcg
    31561 ctaggtcttg ctgatccaag gaagcaatca ttttttcact atttaacatg gtccttaacc
    31621 tcctcaatca ccaatacttc ttcgtcatac aaaccgctaa cttttttgta ccagtcaaat
    31681 aattctttaa tcacaacttt gacagaagcg tagattggga tgacaaggaa aacaccccag
    31741 acaccaaaca tagagcctgc agtcaataac aagaacataa tggtaatagg atgaatgctc
    31801 agcttatttc ccaaaacaag cggtgctaca aaacgccctt cgatggtttg ctcaatcata
    31861 aagataacaa gcaccttaac caacataaat gggccttgta ccatagccat aatcacaaca
    31921 ggtatcatgg caaggaaact tcctaagtaa ggtatcatgt taagaaagcc agcaataatc
    31981 ccaaaagtga tggcatattt cagtcccaca aggctaaaca tgatagaaaa cataaagccg
    32041 acaacaattg caaccgtaac ctgcccttgg acatagcctg ataattgctt gttaatatct
    32101 cccaagactc gaaccatagg cacccgtaat ttgagaggta agacattcac aaggccattt
    32161 ttcatgtggc tactgtctcg taaaaaataa aagagaataa agggcgaaat aataatagcc
    32221 acggtaatcc gagcaatggc accagcaaaa ttaccagccc agtcaatagc attttttgaa
    32281 aaactttgcg cgtaatccaa agccttttga cttgtatggg taagcatgtc ttggagttgg
    32341 ggcttgtagc tgactaacca ttcattttca agaaatttat tggcttcttc attgaccttg
    32401 cccacatatt tgggcagatc ctcaataaaa ctggtaagtt gggtctgtac catgggaaca
    32461 aagcctgaaa tcgcccagac aaaaagtaag gtaatcaaac caaaaacaat aaaaatagag
    32521 gtggtacgat tcgggcccaa gtgattaata aggtcaacta agggtttggt cagataatac
    32581 agaatggtcg aaataaccaa gggcaacatg atgaccgcaa aaaaagaaat cactggcata
    32641 aataaaaaag agattttagt aaaaacaaaa atcgttaaaa aggctaaaag tgttattact
    32701 aaagccatgg tagcttgatt atttaaaaac catttgtaaa ataagctatc tgttctagac
    32761 ttgtcaggta ttaagggcat taagataggg ttcctttctt tgggaaaatg ataagtttta
    32821 ctggtaacct gggtaaatca ataaaaggtc acagatttat ccatgagttg gttgttttgg
    32881 tcataggtaa atttggcaga gaaaaaagga cggtcttcta aaatccattt aaaaatgtca
    32941 taatcacctt cccaagttgg cttttccaac acttgatcgt aaggtaccca ttccaaggtt
    33001 ccttctcgtg actcttcatc ggaaatgagg tctccttcaa atcctgttac tttaaaaaca
    33061 taggtatacc agtcatgacc aggggtaaat tctggaaaag taatgattcc tttaaaggcc
    33121 atctctgtaa cagtcaaatg ggtttcctct aaaatctcac gacgggcaca ctcatctggg
    33181 gtctcaccag cctcgagctt acccccaact gaaatccact tgcctttgtg gacatcattt
    33241 tcttttttat tgcggtgtaa taatagcaaa gaatcgccat tatcaatgta acaaatggtt
    33301 gctaattgag tcatctatct ctttcctttc catctttgtt tctattatac caatctctag
    33361 aaaatatgct atcattttat gagtcaaagt gtgaatactt agtcacgctc aaaaccttct
    33421 aaagatgcct taaaaaagtg tagataagag cctacaatga aaaacatcaa tttaaactat
    33481 caaaagaacc ttgtcatatc aacgataatt gatatgacaa ggttctttaa tgttttattt
    33541 aatcacttct tgagttttag catacttggc ttctacagca tctttttctg ctttccacca
    33601 tgtctcattt tctgtatacc acttaatagt ttcttccaaa ccttctgaaa agtttgtaaa
    33661 ttgtggttcc cagccgagtt cttcacgcaa ttttgtagaa tcaatagcgt aacgaagatc
    33721 gtgaccagca cggtcagtta cgtgatcata agcatctttt ggttgatcca ttttctcaag
    33781 gataagctca agaacttcct tgttgttttt ctcgccgtcg gcaccaataa ggtatgtttc
    33841 accgatacga cccttagtca aaatagccca tactcctgta gaatgatcat tagtatgaat
    33901 ccagtcacgg acatttttcc cttcaccgta tagttttggc ttgatgcctg ataaaatatt
    33961 ggtgatttgg cgaggaataa atttctcaat gtgctggtaa ggtccgtagt tatttgaaca
    34021 atttgaaatg gttgctttca caccgaagga acgtacccat gccttaacga taaggtcaga
    34081 agctgcctta gttgatgagt aaggtgatga tggattgtat tttgtttcag cagtgaattt
    34141 ttcacctggt ccttcaccct gtcctggaag gtcttcacga agtggaagat ctccataaac
    34201 ttcatcagtt gacacgtggt ggaaacggat atcgtattta cgagctgctt caagcaaagt
    34261 gtaagttccg ataaagtttg tatggataaa tggacttgga tcttccaatg agttatcgtt
    34321 gtggctctca gccgcatagt gaacaatagc atccgctttg gcagccaatt tgtctaccaa
    34381 ttcagcgtca gcgatatcac caacaactaa ctcaacacga tcaccaagaa tagcttcaat
    34441 gttagcacgg ttacctgcat atgtcaattt atcaaggaca gttacatgaa catctgggtg
    34501 gttattgtag acatagtgta caaagttaga accgatgaaa ccagctccac cagttacgat
    34561 aatattttta tacataagat ataaagggac ctttcgtttc cgaaaaaatc tattaaaagt
    34621 aatgactcta acaaagacgt tttaggccta agaaaacatc gctttctaag atttgagtcc
    34681 catgttcagc tcaaagagag aaactgaact ttcctttcat catttttagt tgttacttgt
    34741 tacctgaagt agagaagaat aactcccctc atatccacct caaatgatta atcccaatca
    34801 tctgagtatg ttgtttccct ataggtcttt tggtttcagt ggtttgacat cactaagaag
    34861 aggatggttt ttatctgctt cagaaacttc tacagctgct agattttccc aagtaatccc
    34921 aagacttggg tcagcatagt ttacaaaagc atacttaggt ttcaagtcaa gagcccagta
    34981 gtcattgaca agataactgt aagagacagt ctctgaaaga acttgaaagc cattagcaac
    35041 ccctctagga acaaacattc cttttgaagc atcaatcact gtctggtaga cgtttccaaa
    35101 agtctctccc tcacgaagat caacccaagc ccctaaaacc ttgccatcat cagcaactga
    35161 gatgtattta tcccaaggtt cagcatgaag tccacgcagc acatgctgac gtgaaaaaga
    35221 aacgttgttt tgtagttttc cttcctcaaa aaaacgttct ggaaagccaa ttggcaacat
    35281 tttttctttt tggaaatttt ctttaaacca gccacgatta tccccacgaa caggaatatc
    35341 aaactctagt aagcctggga tttctttgat ttctcggcaa gccaatggtt tgtcaaaaaa
    35401 agtttctgtc attaagcttc tccaatcaaa cgaagcaagt attgcccgta ttcgtttttc
    35461 tttaaagatt gcgccaattt atggacatct tctttactga tataacccat gcgataggca
    35521 atttcttcca gatttgccac ttgagcgttt tgcaagcgtt gaacagtttc aatatattga
    35581 gccgcttcaa gtagactttc atgcgttcca gtgtctagcc atgcaaaacc acgccccatc
    35641 aattcaacgg agaggtcacc acgatccaag taagccttgt tgacgtctgt aatttccaac
    35701 tcaccacgcg cgcttggttt aatgttttta gcaatctcta ccacgtcatt gtcatagaaa
    35761 taaagtccag tcactgcaaa gtgggactta ggcacttctg gtttttcttc gatagagata
    35821 gcattcatgt tctcatcaaa ttccaccact ccaaagcgct cagggtcttt cacttgataa
    35881 ccaaaaacgg tggctccttt ttctttggca gctgcctttt gaagcatttt agtgaggcca
    35941 ttaccgtggt aaatattatc tcctaaaata agagcaacac ggtcatcacc gataaactcc
    36001 tctccaataa tgaaagcttg tgctaaacca tctgggcttg gttgttcctt ataggataag
    36061 ctaatgccaa actctgaccc atctcctagc aattcttcga aacgaggaag atcttggggg
    36121 gttgaaatga ttaaaatatc tttaatccct gccaacatca aggttgacaa tgggtaataa
    36181 atcattggtt tgtcataaat gggcatcaac tgtttagatg cggcacgggt cagtggatac
    36241 aagcgtgtcc ctgaacctcc tgcaagaata atacctttca tagtagtgct cctattcttc
    36301 tatataccct atcattctat cattttttga aagcagtgtc acgctttacc agtagaccgc
    36361 aaaaggtaag gctcaggaga atagtcgcta ggcgtcaaaa gtccttcgtg tcctagcaat
    36421 aattgagcta attcatagcc aatcaaaggt ccaactgtta atcccgatga ccctaaacca
    36481 ctagctgtat aaaggttctt caatcctgaa acctgaccat aaaaaggaga ataatcactg
    36541 gtataagctc ttattcctac acgacacgtt ttttgagtag cttcttttaa taacggcaaa
    36601 taagtaagag cttgcatttc aagtttttct aaaacctgcc aatcaggctc caaatcataa
    36661 cctttatcat tttcgtgact cgcaccaaca gaaatcttac cttggttaaa aggaataaga
    36721 tctatttcac cttctggcat aacaactgga taagtgtcgc tgatgatgtg atgaacgtca
    36781 taatccaaga gttgtccctt ttgtggtcgc acatcaacct gatagcctaa aggcctcaat
    36841 aagtcaggta gccatgctcc tgctgccaga atgacctgat caaaataatg accagcaatc
    36901 tcataaccac ttccttgctg tttcagagtg actttttggc gaataactgg ataaccacta
    36961 gccttgagta atgtctcaca taaagcggct ccctccactc tagcagctcc tgaagcgtac
    37021 agacagttat caaagccaat caatccttta aaatcattcc ccagttcttt acgattttta
    37081 atggctaact caccaataat cggtgattct acctttcttg ctaacgctaa ttcataaaga
    37141 tctcttagtt tttcttcctg cttttttaaa acatagatgc cattttgctg ataaaaatct
    37201 gttgcaaaac catcttcttt gaggtcattg attaattgct gataaaagtc cgctcctaaa
    37261 cgagccatgc ggtaccaaac tttattgcga cgctttgaaa accaaggact aataatacca
    37321 gcagctgcct tagtggcttg tccttgacca tggtcaaaaa tggtaacttc tttttgacca
    37381 ctttgttgta aataataagc ggcggttgat cctacaatcc ccgccccaat aatggctatt
    37441 ttcattcctg gtatcctttt atcttatttt aagaccttaa cagcctataa atggctgaat
    37501 ggattggtcg aggctttgct tgaaataatg ctgacatccc aaccgttctc ttctttccac
    37561 ccttggagtt tctcctttaa tttctccgta aaaagcacct caatatgatg ccccgggtca
    37621 accgcaaata gtccttctgt cagcatctcc tgtgctgtat ggtaatagat atcccctgta
    37681 atataaacgt ctgcgccttt ttgcacagca tcctgataaa attcaccacc acttccgcca
    37741 cagatagcaa tctttgaaat caaagggttt tccttatcgt aacggataag tcgcacggta
    37801 tctaaatcaa acaccctttt gaccttactt gctaactctt ctaacgcttg ttctttaact
    37861 gttccaatac gaccaatgcc aaagccttct ttagtttcag acaagtaagt tgcttccttg
    37921 atttctagca ggtcacaaaa ccaatcattt agtccgcctg gtacaatgtc aatattggta
    37981 tggctcacat agacagaaat gtcatgcttg accaaatcta gaaggatatc acgctgaggg
    38041 gatgaaacca gatctttaag cggtttaaag atgggagcat gcttagttat aatgagatca
    38101 acttcatttt tgatggcttc tgctactgtt gactctcgga tatctaaagt aatcataacc
    38161 ttacgaatgt ctttatccaa tgaacccatt tgaagacctt taacgtctcc ttccatagat
    38221 aaatcaagtg ggcaaaaggc ttcataggca tcaattaggg ttttagcttt catgaacaat
    38281 cacctctttt atttgttgta tttttgtcaa gagaagctga cgctcttgag ttttttcttc
    38341 tgggatgcag gacaaggcat aagctaactt atccatttct cgttgccact tctctttaaa
    38401 aacgactgat ttttcctgag aaaggtatgg accaaaacgc aattctgtcg cggataaggc
    38461 cttttcacca tgctcagcaa cgatgatttc ataatatttg tcattttcag ccatgatggt
    38521 ttctgcaaca attttaaaag cgttaaccga taaccaagcc cgtaaatcat cctcacgatt
    38581 gttgggctgt aaaaccagac gttcaatgcc ctgcaatttt tccttacctg cctctaaaat
    38641 atcagcaatc agacggccac ccatgccaca aatggtaatg gctgtcacat catcagcttc
    38701 ttcaaaggct gcaaggccat tggctaagcg cacctgaata tgctcggcaa gaccagactg
    38761 tgtgacattt ttaagagcag attcgtaggg acccctaacc acttcgccag caatggctgc
    38821 tgaaatctga ttagtttcta ccaaagatat gggaagatag gcatgatcac tgccaacatc
    38881 taataatttg acaccttttg gaacataggc cgcaacttgg gctaaacggt ttgataattg
    38941 actatccatc ttgatttctt tctaaaacgt aatggttcta ttatagcaaa attacctcca
    39001 taaaaaaaga aaaccaaagg ctaggctttc gattttccat aagtattttg atagtacttg
    39061 cagtaagact gaacgggaca aatctcacat tttggttttt tggctaaaca atggtagcgt
    39121 ccaaagaaaa tcaatcgatg gtgagtaata atccaatctt tctttggaat tttagccatc
    39181 aaatctgctt caatctgctt gacatcggca tctggtgatg aaatattgag cctctttgag
    39241 actctagcca catgagtatc aaccgcaata gctggaacac cataaacctc tgccaatacc
    39301 acattggctg tttttcggcc aacacccggt aaactttcaa gctctttgtg ggtttttggc
    39361 acttgaccct taaaatcatc acgaatagcc tgagcagttt taatgatatt tttggcctta
    39421 tttttataga gtccaatcgt tctcagagca ttttcaacat cagaaagttc agcaaaagct
    39481 aagtcttcta tttctggata agactgccat agtccaggag ttaccttatt gacggcctta
    39541 tctgtcgttt gagctgataa aatcaccgca atcaacaatt gaaaaggtgt ttcccagtct
    39601 aactctccct tagcctcagg aaacatttga ccaatgatgg tcaggacttt tgctaatctt
    39661 gcttttccaa ttctcatgaa tcactccata aattcatcgc agatagaaaa tcctctgata
    39721 tcgtcacttg agaaagatct tcgccttctc taacacgtct atgttcttct acttgtcgaa
    39781 gattaacaat accttctttt cgccaattac gtaagatagc ctggatatat ttccaatttg
    39841 ttttgccgtt gaagacagct tcttttaaag cttctcgtat caaatcagga tctgttttat
    39901 catcacgaag cgttttttca agatcttcta actcaaaagg actcaagaat cgtcctaatt
    39961 cacgttcaaa ttcatcaact aatcgtttga aatggtttgg tgtttcttgt ttgtcaattt
    40021 cagttgccgt ttgactgaca aacaattgat ctaacttggc taacacagga ctcgcatcaa
    40081 aaataatttc aatttctcca gtaagttcaa ttgtccgcat atctaaaagc ccttgactag
    40141 tcaaagatga aatgatttta ttaatatcag caactgattt tccaagcgca tgagcaattt
    40201 gactgggtgc taagtcatct cgctttgtcg tattttgaag atagaaaaac tgccagacca
    40261 aaaaatcatc tgagctctta aaaagatctt tgtaatgaaa aagcaaggca cttgggataa
    40321 ccaaattacc tgacttataa tgttctaaaa aactcataat ccctcaatca aaaggctaaa
    40381 atcgaatcta tagcctttac tactttaaat cccctaatca gatgctgatt aatgtgctta
    40441 tccaggaaac tgcattaaga ctttatagtc atagttccta atagcatggc gaccatttaa
    40501 accttctaac tcaataagga aggcacaacc agctacaata ccaccaagtt tttcaatcat
    40561 ttcaatagtt gcttttaccg taccgccagt cgctagtaaa tcatcgacaa tcaaaacacg
    40621 ttgtccaggc ttaatagcat ctgcatgcat agttaaggta tcaagaccat attctttttc
    40681 gtaatcagca gagacaacat ctcttggcag ttttcctggt ttacgaacgg gagcaaaacc
    40741 aattcctaac tcaactgcaa caggacaacc aatgataaaa ccacgcgctt caggtccaac
    40801 aaccatgtca atatctttat cacaagcgta ctgtgctatt tcacgaatag catagctata
    40861 tgctttaccg tcagccatta aaggtgagat atctcgaaac gtaataccag ctttagggta
    40921 atctttgatc gatgcaatgt aatttgttaa atccatagtt aattctttct agtggcaaat
    40981 tgccaaatat aaaatactct tcattatatc acgaaacata tttttcgtaa aataagactt
    41041 ctgacattat tgtttatctg atacttcatt cgtaactacc tcaataacta ctgtcaactg
    41101 ctttacttat tgatcgtttg atttcaccaa ataatcatac atctctttcg ggctagccaa
    41161 agccatgatt tcttgaaatt tcaccaattc ttttaagtct tggtaaatgt ggctctctga
    41221 aatctctcgt ttttgcgctt gggggttaac cgtcatcagc ccatcgtcaa tcgtcacaaa
    41281 agacaactct tcaaaaattt gaatcaactt aatcagtaaa agtttttcta tgtttaaata
    41341 gtgactcaac tctgtcaatt tatgccgtaa atcaaattca ggaaactgat agatggtttt
    41401 gtagagcttg gcaaactgct ctctgctgcc aaatcctgtt aaataataag gatgtttcat
    41461 ctgattttta aaatagatgg cgtcaaaatc cttgtgaaca aactggttgc gccaggcttt
    41521 gaaatcttca gggatgtcat taatcagaat gactctggca tttgggtctt cttcaatagt
    41581 cggaatacct tcaggaactt tggctgtttt tgtccttaag tcaagaagtt gcactccgtc
    41641 aacacgagca tctactaaca tgaattggag actcgtgttc ccattccaat ggttgacaga
    41701 taaggtaact gctaattcta aaccagtagc ttgtcggaac tcttgcagtt gacttccttg
    41761 accaaaagcc agtacgtcaa aggaagcttt gccctgactg actttaaatt taagatggct
    41821 ctggtcttgc cctatggtac gcgcttgact aacccttatg tccttgacat aaaagaccgg
    41881 cttttgatga ttcatcccat aaggggctaa tttatctaaa ctctttaaaa tatcaaggct
    41941 aaggtcgtcc aaagacagtc tttcatcaat agttaacgta tttttggcag tctgatctaa
    42001 gccacgttct atcacaaact gacaaagaaa gtctgaaaga gcttccaagt tgtcaacggg
    42061 cagggtcatt cctgctgcac cagcatgtcc cccaaaggct gtaaataact cacgcttgcc
    42121 atttaaggct tcaaaaatat taatagcttc taaacttctg gccgagcctt ttgcaaagcc
    42181 attatcaata gtcaaaacga cgaccgtttg tccaatagtt tccatgatac gaccagcgac
    42241 aatccccaga acaccaggat gccagccagc ttgtgccaag acttgaacag gtttttgagg
    42301 atcaaccata gccatcgctt gatcaaaaat gtcttggact aaggccttac gctcttcatt
    42361 ttttttctta atcatcaagg caatcgcttg agcttcttgg tcatcaaagc ccgtcagtag
    42421 ctcaatggct ggattagggt catctaagcg ccctaaagca tttaattgcg gagcaatctg
    42481 aaagccaatg gcgtcttcat taaaatgttc caaatcaata ggagacaagg acatcaactc
    42541 ctgcaagccc actctttcgg tgtgtttgag catggccaga ccatttttga ctaaaacacg
    42601 gttttcacct gtcaagctta ccatatcggc aatggttcca atagctacca agtctagaca
    42661 gtctgttggt aaactttcta gcaaagctgt tgccaattta aaggcaacgc cacagccagc
    42721 taagtgttta aagggataat cagcatcagg atgctcagga tgaatgatgg caaaggcttc
    42781 tggcaattct tcaggcaggc tatgatggtc agttacaatg acatcaactt cctgttcttg
    42841 agcatatcta atcgcttcat gtccggccac gccattatca accgtgataa ttagggacac
    42901 agcttcctgc tcaataaaat atttatagac gctctggttg gggccatagc catctgtaaa
    42961 gcggttggga agataaacca aaggctctgc tcccatcatg tctagggttt ctttgacaat
    43021 agaagccgac gtcatgccat cagcatcata gtcgccgtaa atgagaattc gttcgccctc
    43081 ttcaatagct tgacgaattc ttggaacagc ttttgccatg tcatgtagca agtaaggatc
    43141 atgcagttga gacaagtccg ctgttaaaaa ctcatctaag gcttcttcag tccttatccc
    43201 tcgatcataa atcaactgag cggcggtctg ggttagacct tttgtctttg ctagcttaaa
    43261 gaagccatca tctggcttct tgtcttttat tttccagcta tatttggatt taatcattta
    43321 taattaaata cctttcttgc aagataatca gataatttag ggaaaagggt gtaaaattga
    43381 tgggtcaccg ctaaactaaa gggcaaattc aattctcgtt tatttttccc gataatagaa
    43441 accaaacgct tagccacttg atttggttgg agagtaaatt taccaacgct ttccaaataa
    43501 tgtccagacg ggtcagcttg gtcaaaaaac ttggtggcaa tgggacctgg attcacggtg
    43561 gtcacgtaaa cccctttatc cgctaattct aagcgaaggg cattggaaaa tccgataagg
    43621 gcaaacttgg tggctgaata aatgctcgat ttggctgacg caatcaagcc tgccatggac
    43681 acaatattaa taagatgacc ttgcccctgc tctgccattt tctgaccaat caagcgagca
    43741 aagtgaatac ttgctagggt attgacctga aacatatcag ctatttcttg ggcagaaaac
    43801 tcttcaaagc ctttgaaagc tccatagcca gcattattaa tcaagacatc aatacggcca
    43861 tagcgctggt aaatctgggc gaccattttc tcaatggcta ctggattggt aatatccaac
    43921 tcaaggcatt ctttgttgtc aatatgctga taacagtgtt ctaggcgttc tttgttacgt
    43981 cctaataaaa tcaagctgtc ttccttgggt aactgcttaa caattgcctg agccagtcct
    44041 ccagaagctc ccgtgataac aatgattctt tgtgccatta aataatcact tcctctaaat
    44101 cttgtaccat tttaacattt tcaaatatag tggcggcatc tttttccatc tggcgacaat
    44161 cacgccctaa aaagcgagct gatacatgat tgagcaagag gcgttttgcg cctgcttcat
    44221 gagcgatttg tgctgcctgc atgttggtag aatgcccgtg atttctcgca atccgctcgt
    44281 cacccttacc ataggtggat tcatgaacca aaacatctgc atctttagcg agtttaacac
    44341 tggcagacgt tttgcgcgta tcgccgataa tggtgatgat tttgcctttt ttaggagcag
    44401 aaatataatc tttggcacaa atcaggcggc cgtcttccaa ctcaacgtct tgaccatttt
    44461 taattttgcc aaagagtggt ccgaagggaa cacccgctgc ttttaaggct tctgcgtcta
    44521 gggttccttc taagtctttt tgaactactc gataacccat gcaaaaaatg gtatgcgcca
    44581 gacgctctgc atagaccaca aacttatctg tttccattat tttacctaat gatttgtcat
    44641 caaattcatg aaaatgaatc tgataaggta cacgcgctcc agaaactttt agactagtta
    44701 acacgtaagt tttaatgcca attggtccat aaatatcaag atctgtctgt tcttcactag
    44761 cttgaaaaga ccgacttgat aaaaatcctg gtaatccaaa aatgtggtcc ccatgcaaat
    44821 gagtaatgaa aatctttctt attttgcgtg gcttaatcgt cgtttctaaa atttgtcttt
    44881 gcgttccttc accgcaatca aacatccaga cttcattgat ttcgtctagt aatttcaagg
    44941 caagacttga cacattgcgc tgcttggctg gttgaccagc tccagttcct aaaaattgta
    45001 attccattca atctattctt tctattgggt gatataaatc ataaattctc gttgggcaaa
    45061 atcataatac ttttgaccag aaaatgtttg gctgagagcc cataactcct ctacattaaa
    45121 ccccttaagc atggtgatac cgtttgccaa acggtaaatc ttcgacaaga gtgtgtcatc
    45181 aggcgtaatg tcttcacatt ctccttgctc aaactgctta gcctgcattt taagctggct
    45241 tttgtcttca taaaccatat attgtgggaa aatttgtgtt aattcaaaga agagttcggg
    45301 tttcttaggc tctgcttttt cagaaaatac caatgcaact tcttggtcat tttggtaagc
    45361 aaaaccataa gcttttccag acaaattgag gcgtacaaag ggcttttctt cctcaaaaga
    45421 tggttggtca gtaaaaagcc ccaaagcctt agaaagatta aaataataat cagtcgcagc
    45481 ttgcggtgac tgtttctggt agatttcagc aaagtaggca ttaataacac ttggtggtgg
    45541 tgtaataaaa gctagttttt gctggtctgt caaactggct aacagatggt ttaggtagtt
    45601 ggtatccaga ctagtaaatc caccataggt ttttgctaaa tcaatataat tattcataaa
    45661 aatcgtcaag tctccattgc tgttttgggg aaatgtagcc cgaaatatcc tctatttctt
    45721 ggtcaaacgt gtagtggtct aaaagagcaa ctcgattcaa atcatacagc ttgtacgcct
    45781 tgtcttgatg cattttgatt ctaaaaggaa caaactggtc tcgaatttgg tcaatgatta
    45841 aacgtctcaa gagaattttg ctatcctttg aacgggctga aaccctgata tttggaaaag
    45901 cagtagctgt gaattgttct gctatatcca ccttgttata aatagctaaa cgtggaatat
    45961 taagcatgtc tagctctttt agaaggttta aaaccacttt ttcttgctca ctatgattag
    46021 ggtcgctagc gtcaatcaca tgtaacagca aatccacata tttgctttct tctagggttg
    46081 atttaaaagc agccactaat tccgttggca agtcttgaat aaagcctacg gtgtctgtta
    46141 aggttgcttg aaattgattt tctaaataga gttgctttgt agttgcatct aaggtagcaa
    46201 ataattcatt ggcttcatag tggctgtcat ctgtcaacaa gttcataatg gttgacttgc
    46261 cagcattggt gtagccaatc aagccaattt taaaggtatc tgatcccacc cgacgatctc
    46321 taattgtttg gcgatttttc tctacctgag ttaattgccg ttcaatatca gcaatctgat
    46381 gacgaatcga acggcgattt aactctagtt ggctttcacc tggtccacgg ctcccaatac
    46441 cacctgcttg acgacttaac atgatgccct gtccaaccaa acgaggtaac atatatttca
    46501 attgggcaag gtgtacttgt aatttgccct catggcttct ggcacgcatg gcaaaaatat
    46561 ctaagattaa ctgcatacgg tcaatgactt ttacctctaa aacagcttct agattagcat
    46621 tttgcctagc agtcaaccga ttgttcacaa taactgcatc aatctcatca gcttccacaa
    46681 tcgccttaat ctcatccagt tttcctgagc cgataaaggt tttgctgtcg taacgttctc
    46741 gtttttggct gaaacttgcc ataactttga caccagctgt tttggcaaga ttagctaatt
    46801 ctgtcatgga catgtcaaaa tgttctgttg tctgaagctc aactcctaaa agaatcactc
    46861 tttcttgctg acgctttgtc tcaatcatca cctttaccaa tcctccaaat tccgtaaatt
    46921 ctattataac atatcttcaa cagattctgc taattttgcg tcatgacttc tctttctgac
    46981 caagaaaatc cctgacccta tcatgtacta cctgtgggta atcaggagcc gttatggcag
    47041 tgaagctaac agccattcga ttgcggaacc aagtcagctg tcgcttggca aaacgtctcg
    47101 tgttttgttt taattgatca ctagcttctg ccaaagtcat ttcacctaca aaatagggga
    47161 ataattcctt ataacctatg ccacgactag cctgaacagt cgggtaatgc tcatataacc
    47221 attttgcttc ttccaataag ccgttttcaa gcatacgatt cacgcgctga ttgatacggt
    47281 catagatgac ttggcggtca tcattcaagc cgataataag cggctcataa gccgtctcgg
    47341 cattctctaa ttcatcagca aactgagcca attcaagggc tcggatcgcc cgtctgcgat
    47401 tcacctgctc aatggtaatg ttattgactt gcaagcgttc atacaagtcg tgatcgtcca
    47461 attgctccaa ctcatttcga taggctttta ccgcctcttg atcaacttga cctcctagat
    47521 gataaccttc gagtaaactt tgtaagtaaa gaccagttcc acctacaata attggtaatt
    47581 tcccacaact aacaatgtct gaaatagctt tttgagcatc ttgaacaaaa tcgtaggccg
    47641 aataagactc cgtcacctca cgaatatcaa ttaagtgatg aaccgctgct tcttgctctt
    47701 cttgagtggc cttggctgtt ccaatatcca actgtcgata aacttgctgg ctatctcctg
    47761 aaataatttc tccattaaaa gccttggcta aactaatccc aagtgctgtt tttccaaccg
    47821 ctgtcggacc aacaatcaca actattttta tttttgtcat tttcttgtct ttctattaga
    47881 aaagcgtgtt caaaaacgcc ttttacttga aaattagctt atttttcgct accatatatt
    47941 ataacataag attaaggacc actgaggtcc ttcactagaa atggagaata atcatggtta
    48001 agaaatatca atttgttaaa ggtcttgcta ctggcgtcct agcaactgct gctactgttg
    48061 ctggtgctgt ctttgctgta aaaaaaacaa tcattgaccc tgaagaagaa aaagctgctt
    48121 tcattgaaga aaaccgcaaa aaagctgcgc gtcgtcgtgt agctcgctaa cgtgacaatg
    48181 gatcaattta aaagagacta gcacattaaa gtgccggcct cttttttagt aatctcgata
    48241 actagttagt agtaactgtc tcttgatgag ccaagatact agctgcttta cttattttga
    48301 aatagaaatc tcaggtaagc cccataaaca tacgtgacta aagctgtcgc caacaatacc
    48361 tctcctagca aaagaacctg ccaacctaaa ccttgccaac ctaaaaaaga taaggtcatt
    48421 tttaaggaag tggcactaat cacaaacgga aaggtaaaag ctgaaaaacc tgggttaaag
    48481 ggacgattga gtaagcgagg aagctgtaca accacaaaag catataacag ttgtgagctg
    48541 atgagaagaa agataaccat tcctacttgt ggtctaggaa aggttgctaa ataagacgct
    48601 gaaagtaagg acagaggggc acaaaatgtt gaaatattgg gcattactgc ttgacctaaa
    48661 ccaatcccat aagtcttttt ggccataaaa ggtaaaatca cagcagttaa gagaagacaa
    48721 acccaaaaaa tcacctgtcc taataaaaac tgcctactag caggtgctgt taatgccgcc
    48781 attgcaattc caacaaaaag cacggaccag gaaggaaaaa cgttatccca tgaaaaagaa
    48841 aagacaaaac gatactggta ataaacaatc aggacaagat ttcccaaaaa gaatagccac
    48901 caagtgaaaa agcctaacca acaccctcct gtcactttga gaaagagtga agacaacaac
    48961 atccctgtca taaaaaaagt tggaaaaaca gaggcaatta gaggttgtcg taactgcatt
    49021 ttggtatcgt taaggttcct aaccatgcca acaagcaaga taccatagat aaaaagagct
    49081 gccagaattc ccaaataatt aaaaatcgaa acataagtag ccaataaatt gccaaatgac
    49141 aacgttccta atgccaatcc tgacatgacc aatggtgggt ttttaaggtg tttcataagt
    49201 gtccttttct gcctattaac agctattttt agtgacataa tcttgtttat tttatcacat
    49261 ttcgagcatt tttgacacca cccgcgaaag aaaatttaag gctcttgcca ttgttttttt
    49321 acattctcgc aaaactagga aactgcttaa aaagctaagg agtgaccact cttctctaga
    49381 aaaatgaaag agtagagaag acttggtctg atctttactt cttctttttg atttagtgag
    49441 ctgcattaag cacttgttga acagctgaat cttccaccat ttttgccata aaagctgcca
    49501 gatgcggata attctcgtaa gattttggtg ttttttgaga ccatagcgcc atggcgtaag
    49561 cataagcatc tgcaatggtt tgttgatctc gataaacatg cccactctcc ccaataagac
    49621 tatctaaatg cgtcatagca atatccatcc gcttgtaaga agcttgtttg actttttcaa
    49681 gcgcttgatt gtcttgagaa atagtgtagc gatgagggtt gatcattggc ctaaaaacaa
    49741 ggggaaaatc acctgttaag aagtccatga tttcgttgaa ccgactttct gccaaaagat
    49801 tatcttgggg aatgagctga gatttcaggg tttgtttcgc tataaagggc aagataatac
    49861 ctgcctgtgt gacaatttga ccatcatcaa gctgtaaagc ttaaaccatt cccaaaggat
    49921 tgatggtaag gcagtcttca gaatccagtt ttaccttctc tatctcgtaa tacagaaact
    49981 cacaattctt ttgaaaaggt gctagacaga gttggtgttg acgtcttcgc tgttgatggc
    50041 tctgcatgac aaaatgagct tggtgtccac gttcactggt atcttgttgc aaagtctttg
    50101 caatttggtc tcatcatctg tatcacaaaa aacaaaccag tttcctgatt tgttttgaga
    50161 tattaggcac ctacaaattc tggcaaggat tctccaatag cttctaaacg ttctgcccat
    50221 tcttgacgtg ataaaccatt ttcttgcaca tagcgattac gttcatgtgc acgacattca
    50281 ggtgagcatc ctcgaacata ctttgtttcg ttttcttctg aagcaaaaat ttgtttgtta
    50341 caaaacggat ttgcacaatt gacataacgt tcacaaggtg ttccatcaaa ataatcttta
    50401 ctaatgacag ttggattaac atgattaatt ggcaccgaga tacgatcatc aaaaacatac
    50461 atcgcaccat cccaaagttc accttgaact tccggatctt ttccatatgt tgcaatacca
    50521 ccgtgtaatt gtccaacatc tttaaagcct tctcgaacca tccaacccga gaatttctca
    50581 cagcgaacac cacccgtaca gtacacaaca acacgttttt ccataaactt atctttgttg
    50641 tcacgtaccc attgtggtaa ctcacggaaa ttgcgaatat caggacgaat tgctccacgg
    50701 aagtgaccta agtcatactc ataatcatta cgcgtatcta aaacaacagt atcttcatca
    50761 agcaaggctt ctttaaattg tttaggattt aaatactcac ctgttgtttc caaaggatta
    50821 atatcactat caaagttatt gtcttctaac ccaaggtgca caatctcttt cttataacga
    50881 acaaacattt tacggaaagc ttgttgattt tcctcgtcaa tcttgaacca aagatcagca
    50941 aaacgctcat cgctgtggac ccaatccata tacttctgag ttgtttcata atctccagaa
    51001 acagttccat taatcccctc atccgcaatc aaaatacgac ctttaagccc aatagattta
    51061 caaaattcta gatgtttcgc agcgtactct tgcgcatttt caattgaaac atacttataa
    51121 tagagtaaaa ctctgatttt ttctgacatt ttttctcctt cattgttatt cagttacttc
    51181 ctattatatc taggaaaaac aagtctaggc aagccatttg tttgtctttt tttcacaaaa
    51241 tagatctcaa tttatttttg atgagatggc aatccattac tcctttaagc aaatcattag
    51301 aagctttatt tagaaaatgc taagataaaa caaggaggcc aaaatgactt atgaactttg
    51361 tttagaatat gggacttatc cgttgtcacg tgttgatgct tactggggag aagatcaaaa
    51421 tcccccaaca ttcattcaag aagatcgact gctttgccat aaactagaaa ctatgaatca
    51481 cctgttccat gatttatttg taactattga atcacaattc cattatgttg gttttaacat
    51541 gcctgaaaaa agagcgcaga ttcggatact atatcaagaa gtagctacta tattaaaatc
    51601 caaatataag gattatccaa ttaagattga gacgtttctt ctttaaaaat ctaatactaa
    51661 aaaactcttc ttaaatttta aaacgtttcg aaaaatcact aaatgcttta atagcacttg
    51721 ctaaaaatgg tttcaccatc tcatcaataa ttaaccttga ttacttacaa tcttatgaat
    51781 ctgagtcaaa taaaattcag gctgtggcat tacagagaca tttaaaacct atactcatcg
    51841 ttttcaaggt cagaaagaga atgattttga aaaggttcgt caactcttct agataatttt
    51901 ggacaaattt tggaaaagaa acaaaaaaag cctatcaaat aaggcttttt tatatgattt
    51961 ctatccacct tgagggaatc gaacccccat ctcaagaacc ggaatcttac gtgatatcca
    52021 ttacactaaa ggtggtcaca actttgtcaa tacctttata gtatatcata aaatgaaata
    52081 atatgaaata acttttctaa ccagaagaca ataaaaagtt gaggaaaacc tcaacttttt
    52141 aaatttatta caattcaata tcaccgaaaa gatcagccat tgagaatcca gtttgtgttt
    52201 ctgggagttc gtagtcacgt cttgattcac gttttggacg acgtgggcgt gattgacgtt
    52261 tttcttcttt gttgtctcct tcagcttgcg ctgggcgttc ttcaagagct ttgattgata
    52321 atgatacgcg ctcatcagct gcattcactt caagaacttt aactgttact tcttgtccta
    52381 cagaaagtac atcttttgga ttttcaacac gtttgtgtga aatttgtgaa atatgaacaa
    52441 gtccatcaat acctggtaat acttcaacaa aagcaccgaa gtcagtcaag cgttttactt
    52501 taccttcaac aacatcacct tgagcaagtt tttgttcaac accgtcccat ggtccaggtg
    52561 ttgttgcttt aagtgaaagt gacacacgac cagcttcttc gtcaattgaa agaactttaa
    52621 cttcaacttc ttcaccaact gaaacaactg atttaggtga cacgttacgt tcgtgagaca
    52681 attcagtcac gtgaacaagt ccgtcaacac caccaaggtc aatgaaagca ccaaaacttg
    52741 ttaaacgcgc tacagtacct gtaacgactg caccttctga aatcttagag aacacttcag
    52801 cacgagcttc tttagcggcc tcttcgataa cttcacgacg tgataggatg aaacggtttt
    52861 ctgctgcatc aacttctttg attttagcat caaactcttg tccaacaaat ttttcagtgt
    52921 tgcgaacaaa acgagtgtca atcattgaag cagggataaa tccacgaagt ccttcaaatt
    52981 caactgaaag gccaccttta acagcacggg tacctttaac agtaacaact tcgccttcac
    53041 gaccaacaag tttgtcccag gctttacgag cttccaaacg ttttttagat actaggaaag
    53101 taactgtatc agtatcttta cctactactt gacgaagaac aagtacttca actgtgtcgc
    53161 cagctttaac aaagtcgtta atatcagcat cgcggtcgtt agtcaattca cgaagtgtca
    53221 agacaccttc aacacctgtt ccttcgataa caacgtttgc ttgaccgtta tcaacagtta
    53281 aaacttccgc agtgacaaca tcaccagggt tcacttcgct aacactgttt agcaaatctt
    53341 caaattcatt cattctaaaa aatcctccaa caaaagctag ccaatgctag cttttgataa
    53401 caatatattt tctcaaggta acccgcaacg acaacaactc ttatctttga cggtctcagg
    53461 gagcacctga tacctctgac tggggtagct ggattcgaac caacgcatga gggagtcaaa
    53521 gtcccttgcc ttaccgcttg gctatacccc aaaaatattt ttttacagaa aactaatttt
    53581 ctaattagat tagtttccga aatggaaaga gagggattcg aacccccgaa cccgaaggag
    53641 cggatttaca gtccgccgcg tttagcctct tcgctatctt tccgtaacaa caaaaactat
    53701 tctatcatag tttttgtaag ctggcaagtg tttttgtcta attttaatgg ttcaaattgt
    53761 agttttcaat gatattttca accgcttgtt cgagcgtttt gaagaagcaa tctactccat
    53821 cattttttaa gacagcaaat ttctcatcaa gttctgcaat ttctccaacc acacgtttac
    53881 caatttgtaa ttgatagcca tcaatcttag tctcattaac cataactttg tgatcaatca
    53941 gttggatttc aattttttta tcttttttac tcatcacttt acctcacttt gtctatttta
    54001 cacaaaatca aaaaagcttg caagagcaag ctctatttta atctactttt acaatccaac
    54061 cttctggtgc ttcaatatcc ccaaattgaa tgccgaccaa ctcatcgtat aaacggcgtg
    54121 tcacaggacc aacttctgtt tcactgtaaa agacatgtaa gttatccttg tactggatac
    54181 cgccaattgg agagataaca gctgctgttc cacaagctcc tgcttccaca aatttatcca
    54241 attcattaat tggaacatca ccctcaatta ctgtcatacc aagtctttct tcagctagtt
    54301 gtaagagtga atacttcgta atagatggca agatggatgg actaagtggc gtaacaaatt
    54361 cattatttgc agtaatgcca aaaaagtttg cagctccgac ttcttcaatt ttagtatggg
    54421 ttgctggatc taagtaaatc acatcagaaa agcctgctga tttagcggcc ttacctggta
    54481 gcaaacttcc tgcatagttt cctcccacct tagcagcacc tgttccgtaa ggagcggcgc
    54541 ggtcaaacgc ttcagaaaca ataaaattag ttggagcaag tccacctttg aaatagtttc
    54601 ctactggcat ggcaaaaatg gtgaaaatat attcttcggc tggtttaacc ccaataatat
    54661 ctccaactcc aattaataac ggtctcaggt aaagcgttgc acctgttccg taaggtggta
    54721 caaagtcttc attggcttta accacttgct tagctgcatc aataaattgc tctgttgata
    54781 cttgtggcat caacaagcgg tctgctgtgg cttgtaaacg cactgcatta cggtctggtc
    54841 taaatagttg aatagagcca tctttggtgc gataagcctt taagccttca aaagcttgtt
    54901 gtccataatg aagcgctgga gcgctttctg agatatgtaa ggtggcatct tctgttaatt
    54961 gacctttatc ccattgacca tttttgtaat aagaaatgta acgaaatggc aacttatgat
    55021 attcaaatcc taggttgtcc caatcaattg ctattgtcat catcgtacct cttttctgct
    55081 tttttctatt gtaacttttt ttcaataatt ttcaagttta ttctattctt ttgcattaat
    55141 attctaaatt taccataaaa ttaaaaagag ttttcactct ttttaacgtg ttctagctac
    55201 cagtacttct tgatccgaaa tagtgtctga aataaaggag ccattgctgg ttctttccga
    55261 taacgaaagc gtttctaaag caatctcgta ggtttgacca gtcttactaa tgacttcaag
    55321 tatttgttga ttagtttctt cttcaggtat atcagtgaac aaatcaaact gctcagctga
    55381 agtatctgat tgaacgcctc cggccagaaa aactctatga ggtttggttt ttaactctcg
    55441 taggaccaat agtccacgat tggcacgact tgtctgagga atatcatcga cagccatccg
    55501 tttgagagaa cccctctgag ttaagacaaa gaaagagtta cttgtcacag caaaggctga
    55561 ggcaaggctg tcatcatttt tcaagttaat gcctttaaca ccagcagatt tcaacccttg
    55621 aataggcact tcctgactgg agaatcgcaa agcataacca tttttagtca ctaataggag
    55681 gtcttccata ataactggtg acaaggtaac cacgcggtct ttgtcatcct ttagcttcac
    55741 atatttggtt gatttagatt tataagttcg ccaaggactt agttctttac gatcaaagcg
    55801 tttgataaaa ccattttgtg tgacagccac atacaagccc tggtcaaagg aagtcacaat
    55861 atcagcgtag agaatctctt cttctgtcgc gaagtttgaa atggtttgtg ataaatgttc
    55921 accgatatct ttccaacgta aatcggtcaa ttcatggatt ggccggtaaa tgacattgcc
    55981 taaagttgta aacaacaaaa ggtgttctgt tgttttggcc tgtttaacga agatgagttc
    56041 gtcatcatct ctcttgccaa cttcttccaa actagacgca ttgaaggatc gtgggctggt
    56101 tcttttgagg tatccgcccc gtgtcacact aacaaaagtt tcttcctctg caatcaagct
    56161 ggcagtgtca atctcaatga tttgactttc tgcttgtaac tctgataaac gaggattggc
    56221 gaatttcttt ttcacttctc ttaattcacg tttcatgacg ttatacatgg ttgcttcgtc
    56281 accgataata gcggaaaggg tcgtgattaa gtctcttaaa tcattttctt cattttggag
    56341 agtaacaata tcggtattag ttaaacgata aagctgcaag gttacaatcg cttctgcttg
    56401 ttcctcagag aaatcatagc tgactttcag attttcttta gcatcagcct tattgtcaga
    56461 cgatctaatc aaagcaataa tctcatctaa gatggacaag acacgaatca atccttcaac
    56521 aatgtggagg cgtttttcag ctttggcttt atcgaattta gaccgctcaa taataatatc
    56581 tttgcggtga ctgatatagc ttgataagat tttttgaaga cctacttggc gtggcgtaaa
    56641 gtgatcaata gcaaccatat tgaaattgta attaacttga agatctgtgt atttcaacaa
    56701 ataattcaaa atggtttggc tatcagcctc ttttttcaac tcaatagcta tgcgaagacc
    56761 tgtgcgatca gattcatcgc gtacttctac gatgcctggg actttattgt taacacgcac
    56821 atcgtcaatc tttttgacca agactgcttt gttaacttca taaggaatct cagtgacaat
    56881 aatttgttgt ttaccacctt taagttcctc gatttctgtc ctagagcgaa caacgacacg
    56941 tcccttacct gtttcgtagg cttttttgat ttcgtcagct ccttggataa tgcctcctgt
    57001 cgggaaatct ggcccaggca aaaattccat caatttctct aaactagctt tgggatgatc
    57061 aatcatatac acaacagcat caatcacttc tgacaaattg tgcggtggaa tatctgtcgc
    57121 atagcctgcg gaaataccag aagacccatt gacaagtaag ttaggaaaag ctgctggtaa
    57181 aactgtcggt tctttttctg tgtcatcaaa gttccacgca aaagagaccg tatttttctc
    57241 aatgtcttga agaagataac ccgcaatttc agacaagcga gcttctgtat aacgcatagc
    57301 cgcaggcgga tcgccatcca ttgaaccatt atttccgtgc atttcaacaa ggatttcacg
    57361 gttcttccaa tcttgactca tccgtaccat ggcatcataa atagaggaat ccccatgcgg
    57421 gtggaaattc cccatgatat taccaactga tttggctgat ttacggtaac ctttttcaaa
    57481 agtattacca tccttattca tcgaataaag aatccggcgc tgaacaggtt ttaacccatc
    57541 tcgaatatct ggaagcgccc gttcctgaat aatatacttg gaataacggc cgaagcgttc
    57601 tcccataata tcctcaaggg acatgttttg aatgtttgac ataagttcat gatgcacagg
    57661 ctatcaagaa ggacaactac ggtcgttcaa aaaacaactt aaccgctgat gtcttttatt
    57721 atgttaacct gagttcaaat cctttcttaa aagttgaagc aagaggaacg tgaaaatcac
    57781 tcgaaaacca agattttagg aaaaagagat gtcttcgata acgtaagcca tcgggaaaac
    57841 tagtcggcca tctcaaggtt tactaaaaag cgataaacag aatcagtcca ctctatcaat
    57901 ccttcctgat ggtaaggtaa ataaaaacat cgtgctttaa gtacctctgg aataatagct
    57961 tcaaacaaag aagcttgatc tagaggaata atacacgcct ttaaagcatc cagtgatagg
    58021 tgatttttaa ctttggcagg gtgataacca tcaaataaat aatgctcttg tgctaagacc
    58081 tcctcataag aaaaatggaa actaacacca gggataaata actcatttaa ttccctatca
    58141 tttggtaaat ggccaatgag cctttccata gccaaacgat aacctgaagt agtatttgac
    58201 caccccaaca tcacatagtt aaagtagtcc gcgggatctc ctgcagcatt tctactatct
    58261 tttactaatt cctcagccgg acggttaaaa gccttaactg ctaataggag ttttcctgac
    58321 ttaaagactg ctattgccgt ttccaccgta cacgtatgac taagccaatc accatagaca
    58381 gcttttccag aaacatcata ggttgaggca accttcttat ggcttggagt aaatggcggc
    58441 tttctattat tatgttttaa atactgatta atttttgtta ctatcacttg atctttacaa
    58501 atgatctgag gttcccggtg attcatcctc tcataatgac aaaaagcagc tattttttct
    58561 aattcccaat cctggatcat cgggtaagat tccaaagcaa aatgataggt cccgtcccac
    58621 tgaagactgt atgtgttttg ccaaatcacc aatttcataa aagcccccct tttcacaagg
    58681 acatgattac tagtttctca tcgagattct cagagacaaa acgactaaaa caccgtattt
    58741 tcttctaagg taaacttgac gttatcctca atccactgac ggcgtggagc ggctttgtca
    58801 cccatcaaca cagaaacgcg tcgttctgct cttgctaaat catcaatagt aacacgaata
    58861 agtgttctgg tttcagggtc catagtggtt tcccataatt ggttagcatt catttcaccc
    58921 agtcctttat agcgttgaag aatagccccc ttgccaaatt ctctgcgcag atcttccaat
    58981 tcgccatctg tccaagcgta agcaattttt ttagttttgc ctttaccttt tgacattttg
    59041 taaagcgggg gaagcgcaat ataaacgtga cctgtttcta ctaatggtcg catataacgg
    59101 taaaagaagg tcaataagag ggtttgaatg tgggcaccat cggtatcggc atcggtcatg
    59161 ataataatct tatcatagtt gatatcctcg aggttaaagt cagctcccac tccagctcca
    59221 atggtataaa ccatagtgtt aatttcttca tttttcaaga tgtcagccat tttagctttt
    59281 tcggtattta aaactttgcc acgtaatggt aaaatagcct gaaatttgcg gtctcgtcct
    59341 tgtttggctg aacctcccgc agaatctcct tcgaccagat acaattcatt tttcttggca
    59401 tttttggact gagctggggt taattttccc gacaacaagc ctttgtcttt tttgtttttc
    59461 ttaccattac gtgagtcatc acgcgctttt cgagcagctt cgcgagcatc tctagcttta
    59521 atggctttgc gaactagatg agaagctact tctccatttt cgagtaaaaa gaaggttaat
    59581 ttttcagaaa caatgctctc tacaataggt ctcgctaagg gacttcccaa tttgtctttg
    59641 gtctgtcctt caaattgcaa gtgctgctca ggaactaaga tagataatac tgctgagagt
    59701 ccttctcgat aatctgagcc ctctagattt ttatcctttt cttttaagag attggtttta
    59761 cgagcatagt cattcatcgc tttggtaata gctgacttta gtcccgtttc atggcttcca
    59821 ccatctttgg tgcgcacatt gtttacaaag gataagatat tgtcggagaa accatcgtta
    59881 tactgcaaag caacctcgac ttgaaagtct tggtcttgac cttccatgta aataacaggt
    59941 gtcaaggttt ccttatcttc attgaggtat tcgacgaaat cttgaacccc attttcataa
    60001 tgaaactctt caataatcgg gtcatctcca cgaagatctg tcaagctcat cttgacattt
    60061 ttcaaaagaa aagcagattc tttcaatcgt tctgaaatgg tattgaactt aaagtcaata
    60121 gttgaaaaaa tcttatcatc aggcataaag gttacaaccg ttcctgattt agacttagga
    60181 gctgtgccaa cttttttaag ggttgtaaca ggtttcccac cattttcaaa gcgctgacga
    60241 tacactgccc cgtctcttgt gatttcgact tctaaccagg cagacaaagc attgacaaca
    60301 gaggagccaa caccgtgcaa accacctgac gttttgtagc caccctgacc aaatttacca
    60361 cctgcatgaa gaatcgtaaa aataacttga acggtgggaa tccccatggc atgctggcct
    60421 gttggcattc cacgtccgct atctgccaca ctgaccgagc catctttatt gataacaacc
    60481 ttaatatcat ctccaaaacc agacaaggcc tcatcgacag cattatcaac aatttcccaa
    60541 atcaggtggt gcaatcccgt agcatctgtt gaaccgatat acatccctgg acgcttgcga
    60601 acagcatcta acccttctag gacttggata gcatcgtcat tataattatt aattgtaatt
    60661 tctttcttag tcaacaccga cctccagaca gtttcatctt ttttatctta caagtttttt
    60721 accaattttg caaaataatt tgctaatttt ttccgaattc ttttccagat ctagttctcc
    60781 aatctatgaa tatgttataa taaggattat gaaattacta ctttttatta ccattgccta
    60841 tttacttggt tctattccaa ctggactatg gattggacag tacttttacc acatcaactt
    60901 acgagagcat ggatcaggaa atactggaac cacaaatact tttcggattt taggtgtcaa
    60961 ggcaggaaca gctaccttag ctattgatat gtttaaaggg acactttcaa tattgttacc
    61021 aattattttt ggtatgactt caatttcatc cattgctatc ggctttttcg cagttttagg
    61081 gcatactttt cctatttttg ccaactttaa aggtggtaag gccgtagcaa caagtgctgg
    61141 tgtattgcta ggctttgctc cgttatatct ctttttttta gcatctatct ttgttttagt
    61201 tctctattta tttagtatga tatctttagc tagtgtggtt tcagctatcg ttggtgtgtt
    61261 atctgtttta atatttcctg ccattcattt tcttttacca aattatgact actttttaac
    61321 ttttattgtg atattacttg cgttcattat tattataaga cacaaagata acattagtcg
    61381 tatcaaacat catactgaaa atctaatacc ttgggggcta aatttaagca aacaagtgcc
    61441 taaaaaataa atttactaaa agcctgactt tctctgaaag tcaagctttt ttgttttaac
    61501 tcatttgtta attagggtaa acgacctctc cgtctgcaat agtgtatttc acgacacctt
    61561 tgagtttgtt accaataaat ggggaattac tagctttaga aacaaaattc tcagtgatca
    61621 gacgttcttg cttgtctgca aaaataacca aatctgctgg accattttct gccaaataac
    61681 ccgcatcaaa accataaagc aaagctggat taagcgtcat tttttctaat agtgacataa
    61741 gtgtaagatg acctggttca accaaatgcg tcaaacctaa tgacaaagaa gtttcaagtc
    61801 ctgtcatacc agatggggct gtagtcatat catcaacagc tttttcatcc ttgtgatgag
    61861 gagcatgatc agtggcaatg actgtgataa cacccgattt caagccttct atgacagcta
    61921 aacgatctct ttgtgtacga aggggaggat tcatctttgc gctggtacct gcggtcaata
    61981 agagatcttc agttgttgaa aaatgttgtg gggacacttc agcagttacc ttagcaccca
    62041 actgctgagc aaaagccact acttgaaccg attctgcttt agataaatgt tggatatgaa
    62101 catgagcttg cctgtcataa gcaatcatga catctcttgc aatcatacta tattctgcta
    62161 caccagttgc cccacaaaaa tgaaaatgct cctcagcaat accttcatta aaaccaagaa
    62221 ccccatttaa ctgaggatct tcctcatgca aagaaatgaa agtttggttg gcattagcca
    62281 aatcaaaggc ttcttttaaa actttagaac tttctaaggg aataccatca tctgaaaagc
    62341 ttactgctcc tgcttccaac aaagctttaa aatcagtcac gtcttttcca ttaaaggctt
    62401 gggtgacact ggcattggtg taaatatgaa tcttttcttt agctgcgcta gctagcactt
    62461 cctgtaaagt ttcgacatct gaaatgacag gattggtatt agccatcatg acaaccgtag
    62521 tcacaccacc tgctgctgct gccaaggctc ccgtgtgaat atcttctttg tgcgtttgac
    62581 cgggttctct aaaatgcaca tgaatatcga ccaaacccgg ggcaacaata agaccactag
    62641 catcaatcac ttgagcttct tggcattcaa tagctgaagc tatctttaca atctgtttac
    62701 catcaatcaa gacatctgcc acttgatctc tctgcgattt cggatccata acgcgtccat
    62761 ttttgatgag tatcatgttt tctcctttat ttatctgttt taaccataag accttacgtt
    62821 ctttaatagg aaaaatctac tgcgctcatt tcacttatta aaggtatcaa aatgtctagc
    62881 ttaagctatt tagttgaaat ggctggctta ttttagccaa tctacgccag tcatgccctc
    62941 tttttctaaa atagcgttgg ttcttgaaaa aggtttgctg ccaaaaaagc cacgataaga
    63001 tgacaaaggg cttggatgag ggctctcgat gatgtggtgc tttggattag taatgaaggc
    63061 ttttttcttc cttgcataag ctccccacaa aatgaaaact acagggctgt ctttctcatt
    63121 cagcacttta ataacagcgt ctgtaaatgg ctcccatatt aagcctgcat gcccattagc
    63181 ctggcctgct ggcactgtta agcaagcatt caaaagcaga accccttgac tagcccaagt
    63241 gcttaaatca tgatggtcac gaggaccaat gtcatctgct aattctttta aaatattaat
    63301 aagggatggc ggagcagaaa tctcttctgg aactgaaaat gataagccct gggcctgttt
    63361 ggggccatga taagggtctt gtcctaaaat caacactttg gtttcttcca aaggagtgac
    63421 ttgtaaggct ttaaagacat tttctcgtgg aggatagaca agaccggaag cataggcttc
    63481 atctaaaaag tgattgatgc gaccgtagta atgctccggc aaaaatgatt tgattttctc
    63541 atgccaaatt gaatgagcca taagattcct ttctaatcac gtcagtttct aagttaaata
    63601 cgatgtcctt ttctatctag tttaccacat tttaaataga aagaccctga aaatatgata
    63661 tttccagggt taatattcgt tttttacagg atattaaaca agtgctagct tattttctaa
    63721 gaattcttgg taacgttcta acaaaaaagc aataagccaa tagataaagg ctactaaaat
    63781 atacatggac atgtaatccc actctctacc gccaataatt ttggcatttt gaaaaatatc
    63841 tggtacggta atcatggcag ctagcgacga acttttaacc atatcaataa tgacattgcc
    63901 tagaggagga accgcaattc gaaaagcttg aggaagaata attttcttaa ccataagagc
    63961 atatggcaac cctaaagcct tagctgcttc ccactgtccc ttgtcaatag cttctataga
    64021 agagcgaaaa acttcagaaa tataggcagc gctaaccata gaaaaaccaa gataagcgca
    64081 aagtaaagct ggcaattcta aaccataata aggcaacccg aaataaagaa caaagagcac
    64141 cacgatcatc ggcacacctc gcataataga gatgtacgct ctaacaagat aatgaatcaa
    64201 cggctgacgt gaccttccca gaagggatag gcctaaacct aaaaacagac ccgtaaaaaa
    64261 actgagcaac gaaataccaa gggtataagg taatcccgat aacacaaatc ctaaactatc
    64321 tttcattaat gggatattaa tcatgtggtt aggactcctt taacatcaag tattagttaa
    64381 cgtctttcgt atcaatgacg ggaatttttt tgtctttgcc aaaaggtttt gtcagatctt
    64441 gaccagcata gtaggtttca gagattttct tcaagctacc atcttttatc atgtctttaa
    64501 taacagcatc tatttttttc ttgaggctat cgtctttttt gttcataaca attccttgtt
    64561 cggttgggtt gtactgaaca tcgctcattt tgacatttag atttggattt tgagataaca
    64621 tgtaatccac aaataatttt tgagctgggt aatcatttgg aatgaaatct gttcgaccgt
    64681 tagccacatc gtttagataa acatctcctg taacattatc gtaggtcacc agttcggctc
    64741 cctgtttttg cgctactttc atgtattctg ttccagaagc accagctgct ttttttcctt
    64801 tccagtcgct aagatctttt ttagccatgt ttgagctgcc atcagcacgg acaatcatgc
    64861 ctcctacccc gtatttataa ggcgtagaga tattgtattt tttctgacgt tttggggtaa
    64921 tgtcaaagtt gttcaaagaa atatccactc gaccactatc aactgaggta aacgcttggt
    64981 caaatcctgt ttcaacaaac ttgactttaa tgttaagtcg tttaccgatt tctttgacca
    65041 tatctacttc gtaacctact aactcattat tatcgttgta aaaagaagtt ggctgatagg
    65101 ttcctggggt agctactttt aacacccctt tttctttgat agtgtcccaa cttgattttt
    65161 gagattgatg tggcgcacat gctgccaata aaaggctggc aagtccgata gacagtaaag
    65221 taactgattt cttcatagta actcctttat taagataaga atagtataac attttgatta
    65281 agttgtgtta tcagtgagcg ctcaatctct ttaaaaagtt aatctataat agttaaactg
    65341 ttttataaga ttattattga ggaatcttca ataatcctgc tgcctcaaac tgctctgcaa
    65401 ttcctaataa taggtcctct ctacctttgg ctgcaattag ttgaatgccc attgggagcc
    65461 cttccttagt ttcgtaagta ggtaaactaa tagctggctg gccagttaga ttaggcagag
    65521 ctgtgtaagg attaatagcc agactcttac caaacatggt ttcgaccaaa ttgaattgct
    65581 cttcactgct gaaaatttca gcttgagcca agttagccat gagtttcgaa tctgggacaa
    65641 gttctccgtg cttaggagct ggtgtgttgg ttgtgaacgt caacaacagg tcataagtct
    65701 catgaaaact agccatggtt gcactgtacg tatcccattt ttgaaggacc tgtgagtaac
    65761 gccaagctgg gatgtcttta cctgattggt aaatagccca ggtcatggtt tccatatcgt
    65821 ctttggtcat cggacgtcca aaagtgtctt caatatcagc aaacatagca gccgtttcca
    65881 cactattcat aatataataa tgacgaatca cttctgtcat atttacagga aactcttcca
    65941 attcaactag ctgatgccct tgttctctta gccaagttac tgcttgtctt aaagcttttg
    66001 cagtatctaa agatactggg ctaccgtcac ttaaccgttg ataaaaagca attgtcaagg
    66061 gacgttgtag cgattgataa atactatctt ttgttaaggt ggctaggggg aaggggcttt
    66121 ccatttgttc catctgtaaa tagtagagta gatttctagt atctctaacg gatttggtca
    66181 aggcaaaatg aactgaggct ccttgccagc ttcgataaga accaggtccg acaggcatgc
    66241 gcccacggct aggtttgagc ccaattaagc cattaaacga ggctggaatt cgaatagaac
    66301 caccaccatc actagcagtt gctagcgcac taattcctga tgacactaga gcagcagctc
    66361 ccccagatga gccaccagca tttcgtgtat tatcctttgg taaattcact ggttcgtgca
    66421 aactgctatc gctaatattt ttaaagccaa attcaggcgt gttggagcgc cctaaaataa
    66481 taaagcctaa agcttctaat cttttcacaa ataaatccgt tttagttgct tggtactctt
    66541 taaacaatct ggaacctgag gttgatgagt gaccttttaa ttcttgtccc aaatctttca
    66601 aaaaaatggg aactcctgca aaaggcttac ctgaaaaatc cctttgtttg gcttcttcta
    66661 gggctgcttc aaagcgttct gaggtaatag catttaaggt agggttcaac tttttagcct
    66721 tataaatagc ctgggttact aattctagtg gtgtggtctg accagtctga acagcaatag
    66781 ccatagccgt cgcatcttga taagtcatag ctactcttcc tttctaagat atgaatccta
    66841 aaacattctt ttttattaaa acacaaataa aagaaaacca ccattaaaag gttagaaatt
    66901 agaatgtgat gtgtaaggaa tgtagacaaa acaatcaaaa cataacattt ggaattgggg
    66961 ctaaagagat tttttcatta aaaataaacc tggctgatag ttccttattg ttgccagttt
    67021 acctggtctt ctttaaattt tttaagtaaa tgtaaaccat cattagtaat atagccttgc
    67081 aactttgcaa ctgcaattag ctcagtataa ttagaaagcg taatcaactt gataccagct
    67141 tctttaaaat tctgactagc ttttggtaac tcataagtga aaatcgcaac aactcccaga
    67201 acgtcagctc cctcacgact ggctgctgcg gctgcatcta gtaccgaacc acctgttgaa
    67261 atcaaatctt caatgataac cattttttgg cctttaagcg cacgcccctc aatctggttg
    67321 cctgctccat gatcttttgg cttactgcga atataagcaa aaggaagagt cattttatct
    67381 gctataatgg caccgtgagg aatacctgct gtagctgtac cagcgatgac ctcaacttct
    67441 gggaaatgag ccctgatagt ttccacaaac ccattctcaa ttaaatcacg agtcttagga
    67501 taagaaaggg tgacacgatt atcagtgtaa ataggtgatt taatgccaga tgcccacgta
    67561 aaagggtctt caggctttaa ataaacagct ttaatatcaa gtaattgagt tgcaatttgg
    67621 cttgctagtg tcatttctta ttctcctttt tcttctttaa cagacaagtg ttggtttcct
    67681 aatcttatct gttagcctgc ccactcagct tttatggctt ggtaagcagc cactgggtct
    67741 tttgcctggg taattggtcg ccctaccaca atataatcac ttccaatgcg tcttgcttgg
    67801 tttggagtca tcactcgttt ttgatcgcca atattactgc ctttaggacg aatgccagga
    67861 gttaagcaag taaatcccgt aggcgtcacc gccttgatag cttctacttc ttgtgccgaa
    67921 caaaccaccc catctagctg agctttagct gcccccttgc tgtaatgcaa aacagactct
    67981 aaaagactcg tttgaatatt ttgatcacca cgcatttggt cttcactggt tgaagttagc
    68041 tgcgttaccg caattaaggt agggccttga cctagtcctt ctcgagctgc ttttagcatc
    68101 tctacaccac cagctgcatg aacagttgcc atatcaatat ctaattcttt aagaactgcc
    68161 atagcagcac gaacagtatt tggaatatca tgtaatttta aatccaaaaa tacattatgc
    68221 cctaacgatt tgatataccg aacaatatct ggtccttgcg cataatataa ttccatacca
    68281 attttcacgt atagtttttc ttctgctgga aataagtcta aaaatgcttt agtctcctca
    68341 aatgatgaaa agtctaaagc aataattggg cgttcttctt tcataactta tcctttctat
    68401 aatgtgtcaa tatctcatta agcaccaaaa agcctcgcta ccaaagaagc gaggctacag
    68461 caaactaaaa gggaattccc tttttttatc ttgtatacct tgtttgcctc tctggactca
    68521 cttaaaggtg tctaaattta aactattata gcttttttaa aacaagatgt caaaactttt
    68581 tgttatttga acacattttt cctactatat ctttttttgt atacttacgt caactcattt
    68641 tatcattttt acccaatcat ttattcaaac tcacctgtgg gtatcttagg gctttggtaa
    68701 tattttataa aagcttcttc ttcaagatta accctctgga tatgttcata gagcacatcc
    68761 ggaataggag cttctttaag tgacaaagca ctcactttta aagatgaaaa aacatcactt
    68821 aagaccccaa aaactcgaat gcgtttatct ccaataataa tttgaaagac ttctttggac
    68881 tggcataaat ctatcagatg atccactcct ttaatccaat tatcgacaat atccaaagtt
    68941 ttgttcatca acttaaaagc tgattcttca taccaaaagg tagactcaat caagcgttgc
    69001 tgcatatcca aggtatcaat ggccgcaaca atatctccca actcagactg tactaaatga
    69061 gctggaaatt cccctccaag tatagaagga gttcgttcta caagcttcag ttcatctcga
    69121 aaaagagtca aatagtggat actgaccaat aatttttgga ttaagatttg atgactattt
    69181 tgttcagtaa cattcacacg accaccaccc tttgattaga aaaataccta tttgttaata
    69241 ctattaatat aacacaagaa aaataaaagg gcaatgaaat tgatagattc aactctcaaa
    69301 attgaatcat atttatccta ggccatattg agaaaagact ccagcgcttt ttcaaagttc
    69361 taaacccatg atgacgtttg tgcttgcgtc tttatttttt ttgagctaga ctgtacttat
    69421 gagaattcaa caactgcatt atattatcaa aattgttgag tgcggctcta tgaatgaagc
    69481 tgctaagcaa ttatttatca cacaaccaag tctatccaat gcggtcaagg atttggaaat
    69541 ggagatgggc attaccattt tcaaccgaaa tcctaaaggg atcaccttga caaaagatgg
    69601 ggtggaattt ttatcttatg ctcgccaaat tatagagcaa acatcactgt tagaagaccg
    69661 ctataaaaac cacaatactg gccgagagct ctttagcgtt tcatctcaac attatgcctt
    69721 cgtagtcaat gcatttgtct cactcctcaa gcggaccgac atgactcggt atgaactctt
    69781 tttgcgcgag acaagaactt gggaaatcat tgatgatgtc aaaaactttc gatctgaaat
    69841 tggtgttctc tttatcaacg actataaccg agatgtcttg accaaattat ttgatgacaa
    69901 tcatttgact gcctctccat tatttaaggc acagcctcat atttttgtca gcaaatcaaa
    69961 tcctctagca actaaaagcc tattaagcat ggacgacttg agcgattttc cttacctgag
    70021 ctatgaccaa gggattcaca actcctttta tttttcagaa gagatgatgt cccagatgcc
    70081 ccacaacaaa tcaattgtgg tcagtgaccg tgccaccctc tttaacttaa tgattggttt
    70141 agatggctac accgttgcca gtggtattct aaatagcaat ctaaatggtg accagattgt
    70201 ggctatcccg ctagatgtcc ctgacgaaat tgacattgtt tttatcaagc atgaaaaagc
    70261 caacttgtcc aaaatggggg aacgttttat cgaatacctt ctcgaagaag taacctttga
    70321 ttaatgtctt tttcaatcgt catactaaaa aaacacggta gtaagacctg tatcggtcaa
    70381 gttatcgtgt tttttgataa atatcagaca atagattgtc tccaaaggct caactccttt
    70441 ttaataatgg cattcatgtc atcaaagtaa aaaggctcac gtcggtagat tacaccagaa
    70501 aaagtcgcca aggtgataat gttttccaaa aaagcctgag aagaaaaatg agtggtgcga
    70561 tgcagttcct cttcatcaaa aggcttaatc aaatgagcca gaggattacg gacagccttt
    70621 tcaaaatgtc gtaacaaaaa aaccaagtcc ttgatttcct gaggtaagga ggtcaacgtc
    70681 aacatgtctg ctaaactttt ggtcgtcaca ttgcgagact gcttttgaga caggtaagcc
    70741 ttaaaaacct cgtgatcaga ttccaacatg gcctgaaaat gccaggtatc atattggtca
    70801 ttctttgtat caaaaatata agccttgaag tttggaattt ctgacgtgat tagtctgaga
    70861 aaaagtcggt aaagaatagg cgacactgac ctgacgaaat caataatagc accgtttttt
    70921 actttaactt ctaaatccaa aatgtaattg gcaatctgct catcttcaag cgattggtta
    70981 agccataatg aacagtggta ctggtcttca atggtccgat tctctgctgc atgttccgcc
    71041 agaaaggcaa ggttcaattc tctgcgctct tttaacatct ctagtaaata gagggcagtt
    71101 ttagggatat ttggcaaggc tttagcaatt ctaaaggcgt gattataagc atagacatcc
    71161 aaaaggatgt ctagtgtttg attattagtc attggcaatt aaagtttcca aaccaacttt
    71221 catcatatca gtgaaagtgg tttgacgctc ttcagctgta gtatcttcgg ttggatcatt
    71281 caagttatct gagatcgtca tgattccaag ggctttgaca tggtgctgag cagctaaata
    71341 gtaaagagct gctgcttcca tttcgatggc tttaacaccc aatttaccaa gagccatatt
    71401 acgctcaggc atgttagtgt aaaagacatc agaagaaagc acattcccaa cgtgagttgt
    71461 tactcccatt tctctggcga tatggtaagc cttgtcaagt aaaccaaaat cagcaatttg
    71521 tgggaaatca aattctggga agtcattacg gataatattt gagttggttg ctgctgcttg
    71581 ggcaagcacc aattcacgca catgaacttc tgggtcaatc gcacccgcag taccaacacg
    71641 gatcaatgtt ttgacaccgt aatcaacgat taattcacga gcatagatag agatcgaagg
    71701 catccccata ccagttccca tgacagaaac gcggtgccct ttgtaagttc ctgtgtagcc
    71761 aaacatgtta cgcacttcgt taaaacacac tgcatcttct aggaaatttt cagcgataaa
    71821 tttcgcgcgc aaagggtctc caggtagaag aattttatca gcaatatcac cttttttggc
    71881 agaaatatgg atagacatta ttaagatatt aaaggcgaca aagaacaaag taaaaatagg
    71941 aaactgacga cgcatcccag atgctagaca gtttatcttt tttacacagt tctccgcccg
    72001 tattcaattc aatgaataca gttagcccta cctttccttt tattttgtag aaggtcagag
    72061 ggcggacaga aagcaactga aatttaggga actaacgcca tgtgtgagca caaaagttag
    72121 tttatctagt ttccgagctt tccgcccgta ttcaattgaa tacaacccca ttcctttcat
    72181 aattgatatt gaatagaaga agagagctaa aaatcgagtt caaataataa aggactaact
    72241 ctctttcctt tattatttaa aaattaatac gaagaaatgt tcgagtccat gcttaattta
    72301 aaccgaatac gtctctttcc cttcgttggt tatgttagtt agaaaagcta gaatctgagt
    72361 tcaacattca tagaactcac accccgtgat tattttttga tttttttatc gcgaacagat
    72421 gtgccaaact gacgacataa aataacattc ctgtaataat gctccagttg attttgttcg
    72481 tcctacaact cagctaaaat agctttaaca agacctttga aatcttcttt gatatgttgg
    72541 gtcacttcca caacttcttc gtggttcaat tctgattgga aaccagctgc aaagttagtg
    72601 atggctgaaa tgccaagtac tttaagtcca gaatgagcag ccacaataac ttctggcaca
    72661 gttgacatgc cgacagcatc tgctcctaat actttgaaag cacggatttc tgctggtgtc
    72721 tcataagttg gaccagttaa gcccatataa acaccatctt ctagtttgat gttcattttt
    72781 tcagccactt catgtgcctt attgcgataa accttagtat aggcatcaga catatcaggg
    72841 aagcgtggac caaactcgtc caagttttca ccgattagtg ggttatttcc ggtcatattg
    72901 atatggtctg tgattgccat caaggtacct gggccgtagc cgataccacc agctgcattt
    72961 gtgacaagaa cgccttcaca tcccagagct ttcatgacac gaacagggaa agtcaccact
    73021 tcaagcgggt ttccttcgta aaaatggaaa cgaccttgta gggcaagtac tttacgacca
    73081 gctaaatcac cgtagactaa ttttccagca tggccaacaa ctgttgattt gccccagttt
    73141 ggaatatctg cataatcaat aacaacagga ttctctactt cttcagcaag ttcaccaagt
    73201 cctgaaccca gaattaatcc aaattctgga gcttcaattc ctttagcaac taaaaagtct
    73261 tttgtttcgt taattttagt catcaatgac atctttttct ccttttacct caatagggtt
    73321 cacactctcg ccatcctctt taatataagg actaggcagg ggaacaggaa gaatatccag
    73381 taaggtctca gaaggacggc aaagttttac tcctttgcga gtcacaacaa taggacgatt
    73441 gatcaaaatt ggatccgtca acatggcatt aataacgtct ttctcagcta ctgcttgatt
    73501 tgctaatcca tgagcctcaa attcaggaac attggttcgc aagagttctc gcgcagagat
    73561 tcccatcgat tgtaagagct caattaaagt ctcccgatta ggtggcgtct gcaaatactc
    73621 aataatagta ggctcaatac ctgcatggcg aatcatggca agaacattac gtgaagtgcc
    73681 acagtttgga ttatgataaa tcgtgatttc ttccattatc aattactaac tttcttattt
    73741 taagtgacca aggaatgact ccccaatcat ggctgtatca actccaaaat tttctgcaac
    73801 agtcgctgaa atatctgcaa aatgcccttg tggaataaga ccatttccag taaaggatgc
    73861 agagtaggca agcaatggaa tgtattcacg agtgtggtcg gtgcctgcat aggttgggtc
    73921 attaccatgg tcagcagtga tgagaagcaa atcgtctttt ttcatatttg cgatgatttc
    73981 aggtaggcga ttgtcaaatt catgcaagca gtcgcgataa ccctctgggt cacgacgatg
    74041 accaaagttg gcatcaaaat caacgaggtt agtaaaggag aatcccttag taaactcagg
    74101 taattgaaga gtcttaataa gcgtgtcaat accatggctg ttcgacttat tgtgtcccat
    74161 gtcgtttgta atacctgaac cattaaagat gtcattaatc ttaccaacgg cataagttgg
    74221 gacacctgcg tcagccagtt tgttcaaaac ggtatcttgg aaaggagaca ctgcatagtc
    74281 atgacggtta gccgtacgtg taaagtttcc tggttcgcct acataaggac gcgcaataat
    74341 acggcctaaa agggcagggc gttcaagcgt gatggagcga gcatattcac aaatcttgta
    74401 aagctcttcc acaggaataa tgtcttcatg ggctgcaatt tgaagcactg ggtctactga
    74461 ggtgtaaaca atcaactcac ctgtttccat ttgacgcgga ccaaaatcat caataaccgc
    74521 agttcctgaa taaggtttgt tggcctcgcg aatgattttg cggcctgaga attcttcaat
    74581 cttagttaaa atctcttctg ggaaaccatt ccagaaagtg tcaaaaggtt ccgtaatgtt
    74641 caagcccata atttcccaat ggcctgtcat ggtatctttt ccaagagata cttcttccaa
    74701 tttggtcacg taaccagtag gattatcttc tgttggaaca gtttttagtg gtattggacg
    74761 agaaatgttt ccaagtccaa tttttgccat atttggaacc gataagcctg ctgtttctga
    74821 aatatgaccg agggtgtcag aatctgtatc agctacacca gcattaaaga atttgtcagc
    74881 atctggtgct gcaccaatac cgacagagtc taaaacaacc aagtgaatac gattaaattt
    74941 tgacataagt ctccaatcta ggggaggtta cggttgactc cccaatacct ataaaataca
    75001 ttaacactgt tatatgctaa gactagcttg ctttaggcgc ttctaaaaca gtaacgccgt
    75061 ctttactagc aacaatcacc ttatcaacca taccattaaa gagaccgtgt tccacaacac
    75121 caactgttcc atctaacagg tgaccaaaag caacaggatc tttaatacaa cccaaatcaa
    75181 gatcaataat atagttttgc atgtctgtca ccaaacgact atcacctttc atacgaaaag
    75241 acggtttgta accagctttt tcaaagacac ggaacaaacg atcagcacca tattgaacga
    75301 cttcgactgg taacttaaag gcacccagat gctctaccat tttagaagca tcaacaaccc
    75361 agatgtattc ttttgttggt gttgcaacaa ttttttccat tagtaaggct gcgccgccac
    75421 ccttgattcc attgaaatcc ttatccactt catcagcacc atctacggtg aggtcaatgc
    75481 tatcaatatc atctatcgat tttaaaggaa tgcctaagcc ttctgcttgc ttgctagtca
    75541 cacttgacgt agtcacacca accacttgca gtccttcttg ctttacgcga cggccaattt
    75601 cctcaacaaa atagtaagcc gttgacccag ttccaagccc aatggtcatg ccatcagtca
    75661 catattgcgc agcggtaaca ccggcaattt ttttgagtgc ttccatgatt cccccttata
    75721 atagaattgc gtcttagcac tttattatac catgaaagcg ccaacttgtt aatgaaaaca
    75781 tttgtttttc tctcattgac agcctaagtg ctatagaata ggatgatctt tttaaaactt
    75841 atgatttatt ctaaagtcat catataagca cttacttttc gtgtttattt agctttttga
    75901 aaatcaagtg tttttgtttg acctttactg accttttgat tataataata ctataagatg
    75961 agtaaaaata atgtctgaat cattttatta gcaaaggatt tcctatcatg tgaaatccta
    76021 acaacgattc tgcgactgct tacaaacatc ttatagtcta ttttttattg cgaggtaact
    76081 gatatgacac atttttctgg taaagatcct tttgtaaata tggatgatat tttcaaccaa
    76141 ttaatggcaa acatgggtgg ttatcgtagc gaaaatcccc gctatctcgt taacggtcgc
    76201 gaaataactc ccgaagaatt ccaacactat cgtcaaacag gacaactccc tgtagcgaca
    76261 accaaagcaa caaattctca aatgttaaca cctaaagctg atagtgtatt gactcaactc
    76321 ggaactaact taacacaaga agctcgtcaa gggcatcttg accccgtcat tggtcgtaac
    76381 aaagaaattc aagataccgc tgaaatcttg gcacgacgaa ctaaaaataa tcctgtcctt
    76441 gtcggagatg ctggtgtcgg taaaactgca gtcattgaag gtttagctca agccattgtt
    76501 aatggagatg tcccagccgc tattaaaaac aaggaaatcg tatcaattga catttctagt
    76561 cttgaagctg gtacacagta tcgtggttcc tttgaagaga ccattcaaaa cttgattcaa
    76621 gaagtaaaag aagctgggaa tatcatctta ttttttgatg aaattcatca aatagttggt
    76681 gctggtgcca caagcagtga ttcaggctca aagggacttg cagatattct taaaccagcc
    76741 ttgtcacgag gagaattaac actgattggt gctactactc aagacgaata ccgcaatact
    76801 attttaaaaa atgctgctct tgctcgtcgc tttaatgaag ttaaagtgaa tgcaccatca
    76861 gctgaagata cttttcacat tttaatgggt attcgtaatc tttatgaaca acaccaccat
    76921 attacccttc ctgataatgt tctaaaagct gctgttgatt attctattca atacatccca
    76981 cagcgtagcc tgccagataa agcaattgac ttactggata tgacagctgc tcatttagct
    77041 gcacaacacc cggtcactga cttaaaaaca ctcgaaactg aaatagctaa acaaaaagag
    77101 aggcaagaaa aagctgtcgc caaagaagac tttgaaaaag ccttagcagc aaaaacacgg
    77161 attgaaacat tacaaaagca aattgagcaa cataaccaaa gccaaaatgt cactgctaca
    77221 gtcaatgata tcgcagagtc tgtagagcgc ttaactggta ttcctgtctc taacatgggg
    77281 actaatgatt tagaaaggct caaaggaatt agcagccgct taaaaagcca tgtcatcgga
    77341 caagataagg ctgtcgcagc agtagcacgt gctattcgac gaaatcgggc aggttttgat
    77401 gatggtaaac gtccaatagg ttctttcctt tttgtgggtc caactggtgt tggtaaaaca
    77461 gagttagcta aacaattagc acttgattta tttggttcca aagatgctat tattcgactt
    77521 gatatgtccg aatataacga tcgcactgct gtgtcaaaat tgattgggac aacggctggt
    77581 tatgttggct acgatgataa taataatacc ctaactgagc gtgttcgtcg taacccttat
    77641 gctattgtct tactagatga aattgaaaaa gctgatcctc aaattattac acttcttcta
    77701 caagtattag atgatggacg attgacagat ggacaaggaa atactattaa ctttaaaaat
    77761 accgttatta ttgctacatc aaatgccggt tttggccaac aagatacgga aacttctgag
    77821 tctaacatta tggatcgcat tgcaccttat ttcagaccag agtttttgaa ccgttttaat
    77881 agtatcatta aatttaatca tctgcaaaaa gaaagtttag aagaaattgt tgatttaatg
    77941 ctagctgaag taaatcaaac caccgcaaaa aaaggtatta gtttaacgat tactgatgac
    78001 gctaaagctc atttgataga tttagggtac aatcacgcta tgggagctcg tccattacga
    78061 cgtattatcg aacaggaaat tcgtgaccgt ataactgatt attatcttga ccatccagaa
    78121 gtcaaaaaac ttcaggcaat cctaaaagaa ggacaactag tgattaggca aaacgatcag
    78181 taataaactt cttcaattga ataattttca aaacatgaaa aaatccgtct tgtgactacg
    78241 ttatacactt gacggacttt tttttagcgc ttttttaaaa ataatttttt catcgcctaa
    78301 taactcaagt ttctttccaa atctggtgta atcaaaataa ccattaggtg tgagtaatcc
    78361 ttttgaaaaa gaagtatgtc ccgctgctac ttcttctttg atatcaatgg tgtgcaaaat
    78421 acgattaact tttcctttga gaacaacagc agataaatgt cctgtttttt gattatattt
    78481 gcctccgatc tgagaagcta atttctcaaa agcttgatct aaaatcattt ctaattcatg
    78541 gctagctggc atactattct caataatttg gcgttcttta ctactcaagt caccaacaac
    78601 taaatgattt tcctttaatg tctttaataa ttcattttgg tgataagcag ctaaacgttt
    78661 gacaaaaatg tctcgttcaa cttgaacact aaaactcaag tcaacgttgt tatttttaac
    78721 tgttagtatc atctgagatg acgttaataa actatcatca ataagagggc tctgatgcaa
    78781 accagtaaga cgtttagcaa aatcatcgcc taacttctga tcaatgcttg ttgttcgcca
    78841 gataccttca atagagctat tacgatatcg aacaccaaaa agtacagcaa gcaagataag
    78901 aaaaataata aatacaaaaa gggcattgca ttgatggcat aacaatgact ttcctttaga
    78961 gcgcccttgg gctacttgtg tcatgactca tctccttaat ataaaatact agcatgtcat
    79021 cattaaggcg tcaagtaaaa tcggtaaacc taactatgat tttttatgtt ttcgataaga
    79081 aaaacaccct ctactgagaa tgttttagca tagataaatc aacacctatc gctagacctg
    79141 ctctaaaata gcatcccaag aatcatcgat accaatacgt tctaccgaag aaaatactat
    79201 aaaagtatca gatttgtcaa aattcaaagc tttcttgacc acagactcat gtttgttcca
    79261 tttgccacga ggaatcttat ctgctttggt tgccacaaca ataacaggaa tgtcatagta
    79321 cttcaaaaag tcatacatct gaatatcttc ttttgaaggg gcatgacgta aatccaccaa
    79381 actcacgact gcacgcagat tgtctctgct ggttaagtat tcttcgatca tctttcccca
    79441 tttggcccgt tcacttttag aaaccttggc atagccataa ccagggacat ccacaaatct
    79501 aagcttgtca tcaatattga aaaaatttaa tagttgggtt tttcctggct tgcttgaggt
    79561 tcttgccaaa tttttgcgcc ccaatatggt attaataaaa cttgatttac caacatttga
    79621 acgtccagcg agggcaattt ctggcaaatc atcttggggg taatgagatt tattggcagc
    79681 gctcaataaa attgatgcgt tatgggtatt taagacttgt tcttcagcca ttatttctcc
    79741 ttaagctgtc tctaaaacgg gttttgactt gccttcgaca gcagccttgg tgatacgcac
    79801 ttttgtgaca tcttcttggc ttggaatttc aaacatgatg tcaagcatcg tttcttcgat
    79861 aatagaacga agaccacgtg ctcctgtctt acgttcaatg gctttattgg caatggcttc
    79921 taaggcttcc ttatcaaatg ccaattcgac gccatcgtaa gaaagaagag cctgatattg
    79981 cttgaccagg gcatttcttg gttctgtcaa aatttgaatc aaatctgatg tgtttagttg
    80041 ttcaagggct gccacaactg gtaagcggcc aataaattct ggaataagcc caaacttttg
    80101 aatatcttct gaaataattt cttgcatata agaagcattg tcatcaattt tacggctgtt
    80161 ttgaccaaaa ccaataactt tttcacctaa acgttgttta acgatctcct cgatgccatc
    80221 aaaagccccg ccaacaataa acaagatatt ttttgtatca atttggatca tttcttgatt
    80281 agggtgcttc cgcccacctt gtgggggaac acttgctacc gtaccttcaa taattttaag
    80341 aagggcttgc tgtacacctt caccagatac atcacgtgtg atagatacgt tctcaccttt
    80401 tttagcaatc ttatctattt catcaacata aataatacca cgctctgctc gttcgacatt
    80461 atagtcagca gcctgaatca gtttgagtaa aatattttcc acatcttctc caacataccc
    80521 tgcttcagtc aaagaagttg catctgcaat agcaaatggt acattgaggc ttttagccag
    80581 agtttgtgct aagaaggttt ttcctgaacc tgttggtcca atcatcaaaa tgttggactt
    80641 ttgtaaatcc acatcatcgt catcacgact ttctgtaaac gagacacgct tataatgatt
    80701 gtacacagca actgataaag cacgtttagc acgatcttga ccaaccacat attgatttaa
    80761 aacatcaagg agctcttttg gttttggaac ttctgtcaaa tcggcaagga cttcttcagc
    80821 caattcttct tttataattt cttgtgataa agctacgcat tcattgcaga tgaaaacatt
    80881 atttcctgcg ataatttttt taacgtcatc ctggctttta ccacaaaatg aacagtatac
    80941 tttaatatcg ttagttctac ttcctgccat ttcttataat tctcttactt tctcttatct
    81001 tttactgaat tttaatatta gtcaatgtgt tgtattggtt tttggtgatt cttgcttgat
    81061 agctaaatct tcaccagtgc tgtctttgca agtcgcatct caaaacaatg taccatagaa
    81121 ggcgtgaata ctattaacca gattagtaaa cgcatttaat aagaacagac ttgctaagcc
    81181 ataacgattc tttttaaaag ctgggatggc acaaagaaca caaatcacgc acaaaaaagc
    81241 cgtaaatact ccaaaaatac tacgttgcat cgcttatcat ctcctcagac tatttgtgtt
    81301 ttaaagcagt aacggtaaaa tcataaggat ttttagcgtc tcgagcatag aacgtttggc
    81361 tttcttgcgt gaaatgacta aaatctagat ttggtcggta ggtatctcct ttaaaacgat
    81421 gatggataac tgtttttatg atacgatcga aataaccatt aaacgcttct aaaaccttat
    81481 tcccaccaat gatataaagt gttttatcct gcgcatggta ccactccaag actttttcaa
    81541 tactagtcat tgtcaacacc tcatctactt gataatctct atttcttgtc atgacaaggg
    81601 tttgacgttg aggaagtctt ttgcaattca ttccttcaaa agtcacacgg cccattaaga
    81661 ttgcttgatg tagcgttgtc tttttaaaat gttctaactc ttttggtaaa taccatggta
    81721 acttacccgc aacaccaata agccctgctt catcctctgc ccaaatagca ataatttcct
    81781 ttgtcattaa ttatttcctt cattttaaac tctatttatt ttaccaaatt tatgaacaaa
    81841 atgctcacaa aaaatctaaa taaagtttaa atagcaaggt caaagtgcaa ctgaggcttc
    81901 actggatcat aattttgtaa ttcaaaatca tctggtttaa tatcaaagaa attagtccca
    81961 tctggaacat ttaaaacaag cttaggctga ctggcaactg gctgtcgttt tagtaattct
    82021 tgagcctgat caaattggtt gtcataaata tgtaaattgt taacaaaata aaagaactta
    82081 cctattttcc atccaaaatg tttagcaatc atcatctgca aggcaacgta ttgcatggca
    82141 ttgatgtgat gagcaactaa tatgtcatta gaacgttgcg tcaaactagc atctaaataa
    82201 agatcttccc ctacacgtct aacatcaaac atgatttgaa aggcacatgg caacaatcct
    82261 tttgtctcct caaatgcttc atagtcccag agagaaatga cattacgacg attccaagga
    82321 ttttctgcta attgctttag tatttttgag atgatatcat gttttttgac tacagcacca
    82381 taacgttgcc caatagtacg tgtctggtca acttcccatt cattccaata atgaacatta
    82441 tatttagctt ctagcacatc taaactgtta gactgatctt gatatatcca aaataattcc
    82501 tttatagcag atttaattgg aataggtcgt aaagttgtga tgggaaactc tcctttagct
    82561 aaatcatatt cagcaaacgc cccagtaata tacttagaat gagctgttcg accatcttta
    82621 tatttaggac gtgcttgctc actcaatgat ccttcgttta taattttttg aatattagct
    82681 ttaaaaatct ggtcagcttt tgtcatctct aataaccttt ctgtaagcat acttcatact
    82741 attctaacta attttaccaa aaaataccag aataaataaa cattcgaaaa acttcatgtg
    82801 gtcatgaaca ttttaactat taaaggataa aacaaataac tttatcagtc taattttgca
    82861 gtaaaatgtg atagaatggg taagactata aaaataacta aaagaaggac aaatatgaca
    82921 attggaattg ataagattgg ttttgcaacc agtcaatatg tcttgaaatt ggaagattta
    82981 gcgcttgcac gccaagtgga tccagcaaaa tttagtcaag ggctactcat tgagtctttt
    83041 agtgtggcac caatcactga agacattatt actttagctg cttctgcagc agatcaaatc
    83101 ttaaccgacg aagatcgagc taagattgat atggttattt tggcaactga atcgagtact
    83161 gatcagtcaa aggcatcagc tatctatgta catcacttag ttggtatcca gccttttgca
    83221 cgttcctttg aagtaaaaca agcctgctat agcgcaactg ctgctctaga ctatgctaaa
    83281 ctgcatgtgg cttctaagcc agattctcgt gtccttgtta ttgctagtga tattgctaga
    83341 tacggtgtag gatctcctgg ggaatcgact caaggctctg gtagtattgc tcttttggta
    83401 actgctaacc ctcgtattct tgctctaaat aaagataatg tggctcaaac tagggatatt
    83461 atggactttt ggaggcctaa ctatagtttc acaccttatg ttgatggtat ttactctacc
    83521 aagcaatatc tcaattgctt agaaaccacg tggcaagctt atcagaaaag agaaaacctt
    83581 cagttatctg attttgctgc agtttgtttc catattccat ttcccaagtt agccctaaaa
    83641 ggtctaaata acattatgga taacacagta cctcctgaac acagagaaaa actaatagaa
    83701 gcctttcaag cttctattac ttatagcaaa caaattggaa atatttatac tggctcactt
    83761 tatctaggat tgttatcttt acttgaaaat agtaaagtat tacaatctgg agataaaatt
    83821 ggttttttta gctatggttc cggtgccgta agtgaatttt attccggtca gttagttgct
    83881 ggatacgata aaatgttaat gactaatcga caaactttac tggatcaacg aacacgtctt
    83941 tccgtttcta aatacgaaga ccttttctac gaacaagtcc aattagatga taatggtaat
    84001 gccaattttg acatttactt aactggaaaa tttgctctaa cagccatcaa ggagcatcaa
    84061 aggatctatc ataccaatga caaaaactaa tcttaactgg agcggttttt caaagaaaac
    84121 attcgaagaa cgcctccaac ttatcgaaaa atttaaacta cttaatgctg aaaacttaaa
    84181 tcaactcaaa acagacgttc ttttgcctat ccaaacagct aatcaaatga ctgaaaatgt
    84241 cttaggacga ttggctttgc cctttagcat agctcctgat tttcttgtca acggttcaac
    84301 ttatcagatg ccttttgtca cggaagaacc ttctgttgtt gctgcagcat ctttcgcagc
    84361 aaaactaatc aaacgctcag gtggttttaa agctcaaacc ctaaaccgac aaatgattgg
    84421 tcaaattgtt ctttacgata tcgacaaaat agataacgct aaagccgcca tccttcataa
    84481 aacaaaaaag ctaattgcat tggcaaataa agcttatcct tccattgtta aaagaggtgg
    84541 aggcgctaga accattcatt tggaagaaaa aggagaattt ttgattttct atctgactgt
    84601 tgatacccaa gaagctatgg gagcaaatat ggtcaatact atgatggaag ctcttgttcc
    84661 tgatttaaca agactgtcta aggggcattg tctaatggcg attttatcta attacgcaac
    84721 agagtcgctt gttactacta gttgtgagat tcccgtgcgc cttttagatc gcgataaaac
    84781 aaaatcccta cagttagctc aaaaaataga gctagccagc cgactagctc aagtagatcc
    84841 ttaccgggct actactcata ataaaggtat ttttaatggt attgatgcag tggtaatagc
    84901 cacaggaaat gactggcgtg ctattgaagc aggggcccat gcttatgcct caagaaatgg
    84961 tagctatcaa ggacttagtc agtggcattt tgaccaagat aaacaagttc tgcttggcca
    85021 aatgaccctc cctatgccta ttgctagtaa ggggggatct atcgggctta accctactgt
    85081 ttctatcgca catgatcttc ttaatcaacc taatgccaaa acattagccc aattgattgc
    85141 atctgtgggg ttagctcaaa actttgctgc actaaaagct ctgacctcat ctggcatcca
    85201 agctggtcac atgaaactac atgcgaaatc attagctctt ttggcggggg caacccaaga
    85261 cgaaattgct cctttagtta atgctttact agctgataaa ccaataaatc tagaaaaagc
    85321 acatttttac ttatcccagc taagacagtc ttagatttaa acaactaata taaggcaaac
    85381 acccatgtaa acaattggtt tacatgggtg tttaatcttt gtttctatac atacaagtct
    85441 tagaaatagt ctccataaca tactctattt actcatctac tctattctga gtttgatgag
    85501 gtattataaa tattttatat tatgttctaa aaaagctcta tcatctttgt agtaggtggc
    85561 actattgtag aggtgatgaa gcctaattga cctgctgcaa gcgtccatat agtaagtagt
    85621 cgactccctt taattcttta atagttttac agtcaagagc acacataatg atttttaatt
    85681 cttctttcca gccgttaacg atagcaatca cacgctcggt tgggtatttt tcgaccaatt
    85741 ctaaaacggt gcgtgagagt cccactgcac gtgctcctag gacgaaacat ttaatcatgt
    85801 ccaaggggtg tctgacacca cccgaagcta agatttccac ttggtccatc agtccttgtg
    85861 catttagcaa gcactgaacg gtggtttgtc cccaatcgtt taagtaagag cggtctcctc
    85921 ctctttgatt ttcaatatag gcaaatgagg tccctcctct tcctgaaata tcaaaggttt
    85981 gaatgcctag gtcatgtgct agcttgatac tattgacatc catgccaaaa ccaacttctt
    86041 tgagaatgac aggaactggt atttgactag cgtattcagc gaggtgtttt ttccaggtat
    86101 gaaagacgcg ctcaccctct ggcatcagca actcttgcat cacattcaca tgaacctgta
    86161 aaaagagggg ctgcatttct tgaaccgttt gttgtcctag cgccacaggt ttatctagac
    86221 caatattcgt ggctagtttc aagttatctg ccacctcatg taaacgatag gaatcgtcgt
    86281 taggattttt taaagcagcg ctataagacc ctgtcaccat gacaatccct gttgctgctg
    86341 ctactttggc caatttttca ttgacagctt tgcttttttg acttcctcct gtcatggcat
    86401 tgatgtaaaa gggaaagtcg aagtcttgcc cggcaaaatg agtactgaga tcaatatcag
    86461 acaaatcata gctaggtaag gaatgatgta tgagttctat atcatcaaaa gcattataag
    86521 gcgattggta cttgagggaa tatttgatgt gatcatcttt acggttggtc attctctccc
    86581 cacctttctt gataaagtaa tgcgatatca gcttcttgcc atttggaaat aagggtatct
    86641 ctggcattct gattaaaggc aagcgcgatg ccacaatctc caccaccaga acctgaagat
    86701 ttagcaacag catcttgctt ctgacaagca gctaccaagg ttactagctt aggatggtag
    86761 atagctggat gaagctcttt taggagatga cttgctcctg ctaaactttt cttgagttct
    86821 tccttatgac cttcttgcaa agctaccata gctgattgcg ttagctggta acttgttctt
    86881 aagaaagctg gggtaatgct cgctgtcact tgttgaatca tctgccttga aatagcaggt
    86941 attttagtcc agccaaccaa aaagtcacaa ggcagggctg gttgaatgac ttggatatgg
    87001 taaccccaat ctttgacgag aagttttttt aagggcatgg tctgcagcca gttactgacc
    87061 tgttctcggt caaaggaggt ataggcgact aaagtctggt aagcgataca ggcaatatcc
    87121 cccatagacc cattatctcc ttgcttaagc aaggtataag ccgctagttt aaagagtaac
    87181 tctggggtta aagtgatctg ataataggcc gataaggcct ttaaggttaa gagggtgaca
    87241 ctaccacttg aaccaatgcc aaattttttg ccatcgcgct ccatttttcc cgttataatt
    87301 agggaaaatg gctccagttg gtcaattgac tgtcctagat aatcagcaaa ggttttaacc
    87361 gttgcttgaa tcagtgcata agaggcatcg ggtgtcatgc ccgctttatg ggcaaacata
    87421 tctgaagcta attgaatatg ggctgctggg ctaatttctg ctgtcatcat cagtggaata
    87481 aagtgaatta aggctttttg tcctggtgtt aagatagcat attcgcctgt gaggtatagt
    87541 ttcccacctg tttgcacaca ataattagac atctggtaaa tcctttgttt ttgaaacgat
    87601 aatacggtag ttcttgccaa gtcgttctgc tagttgagcc aagtcttttt ctaaacatag
    87661 gaccttcaca tttggacctg cgtccatggt aaaataacaa gcaaaacctt cttgacgcag
    87721 ttctttcaca gcctccatag cctggtaaga ctcttttgtt aggtaagaaa aaggaggatt
    87781 ggctgtcttt gtcgtggcat gcatggccaa ggcattagct tctgttaact gaccaacttt
    87841 ctcaaaatta ttagttttga gataggtaag catatgttga taatcgattg ccgattgttc
    87901 tacccattca tcaaatgtag ttgaggtatc gcgacataac ttcatgccct ctcggctaga
    87961 aattggcttt ttcgcagcat ttaagaccag cataatcatg gccattttca agtcagtctc
    88021 aaccttgtaa atagcaccac tatctttgtc ccaagcagcg actgggccaa aaaaagaacg
    88081 agaagatgat cctgaggcga acttagcctt ttgagctaaa gctttctgat ctagctgggt
    88141 gtcaaataat tggtcacagg ctttaaccaa ggctgataag ccactggaac ttgatgataa
    88201 acctgcagct gttggcatat tattttgagt ttccatcttt acaaaagcct gaccaggttg
    88261 gcgaaattgg tcaatgatag cagaaatttt ggtatgttct tcgtcatttt gcaagacacc
    88321 gttaatgtaa aactgatcac tggttacagt atctggtaag aaggaaacgc tggttgtggt
    88381 gaacatgttt tccaaagtca aagaaatgct agaggtcgaa ggaatcatct tagcttgatt
    88441 ctcttttccc caatatttga taatagcaat gttagcatag gatgttacgg ttataacatt
    88501 tggatccacg tgtttacggc tccttcttct tttaatctgt gactgatttt ttcggccatg
    88561 tctttggtat ctgctagggc aatcatacag ccacccaagc caccgcctgt catcttagcg
    88621 cctaaagcac ctgctcttag ggcagcctcc acaagttggt cagctttact gatgctaacg
    88681 ccaatggcct ttaaagcaga atgcgcttgt gtcatgagct gaccgatagc caccttattt
    88741 ttttggttaa tcgctctttc aagggcttgt gtcaaagctc ctagtttagc cagatagggc
    88801 aaattcgttt cctcaaactg tgctacctta ttgacggcct cacgtgtatg accgtgaatc
    88861 cctgtatctg caatgataag ataaccattt aaggcgattt cgatagtttc aaagccaatg
    88921 tttcggataa acttaatggc atggtcacta aggcatgtct tggcatctaa accactagga
    88981 ttggtgtggg caataatttc tgccttgttg actaaaattt ccaacaaatc atccgagagg
    89041 ggttcttgac aataagaaaa aacggctcta atagctgcaa tagaaacggc tgccgaagac
    89101 cccataccac gcttttgtgg cacttgtgaa acaatctcat aagcaattgg ttcttgtagt
    89161 cgctgcaaat aatccaaggc agcataaatg gctgttgata gagtatcata aaaatcaaag
    89221 accaatggct tatcagctgg aaaaatatga caaaccacct caatatctgt taaaggcaaa
    89281 gcaatagctg ggtagccata cacaacagca tgctcaccta tcaaaatgat cttactgtgt
    89341 gccttaccat atccaatgtt ttcgttcatt ttttatcttt tcattactaa ttcttctaaa
    89401 cttttacctt actattttac actaaatgat tagaaaatgc gatgatatat ctttttaaaa
    89461 tcatttcttc actgaaatta acaataaaga ctatctactc tttttaggat cataacaaaa
    89521 attttcttat ttcaaactac cttctttaat cactcttcta ctaaattaaa cgttaaaaac
    89581 cagcctcatg ggctggttaa gcatcgttta ttacctttac ctagacatta ttactagcta
    89641 aaggtactga aaaatgttta agttaaatca ccactgtaaa aacaatagca tcgtttttat
    89701 aatttacagt tatcgttcct ttaaataact taaccatact ttctgccata gataaaccaa
    89761 ttccatagcc tttttctttg ctattatggg attcgtcttc gcgataaaag cgttcaaaaa
    89821 agcggctgta atcaatggat tttccttcca aataggtatt agaaacttct aatttcgctc
    89881 gttttcgtct tcttccaata gtggttaaag ataccttgac caagccttta ggatcacaat
    89941 atttattggc attatcaact aaaattgtca caagttcaaa taatgacttt tcctccgctt
    90001 taatcataat attcggctga atcgtcaaat caaaacgttt accatctttc aaaaccagac
    90061 tcttaaaatc ttcagctgca tcttgagcaa tagctgaaaa gtctaccata tgtaatacca
    90121 catctggctg ttcctccaaa cgagccaaag taatcatttg attaatcaag cctgtcaatc
    90181 gcttcacctg atcacttgta ctcttggtcc attctgattc tccagtcatt aattcgacca
    90241 attcattatt ggctgagata atggctagtg gtgtttttaa ctcgtggcct gcattagtaa
    90301 taaagcgacg ctgcttctca taattttgga caaaaggttt gatgaccata ccggaaaaaa
    90361 gactcactaa aataacaaaa aagataaatc ctccaaaggc caacatcatt gaaacagcta
    90421 ataaatctcc tacactacga aaataaaagg tagtatctaa aataacaacc agtttttctt
    90481 catttggcag ctgagtaatc aagtacgaat aaacactatc ttggtgacgg taactgcctt
    90541 tttcttcccc agacttagca aaaagtctag caaaatattg ggcttcttct ctatctaaag
    90601 ctgaaatatt agcagtatta gaagaaagta gatgtccatt agcattaaaa atgacactat
    90661 aataccgaaa ctggcttagg ctatcttcag acagtttcgt tccaagtcgt ttagagcttt
    90721 ccgtagtgcc aggtaattta cctttatttg aggaaattaa atgtaaaata cggttaattt
    90781 cttgttgact ttggtaacag cgtgccgtgt taataatacc aacaattgaa cttaaaataa
    90841 taaaaatggc aatagaagca atcatgataa aacgaatacg gatacgatta aacatgtcac
    90901 ctcctatttt tctaataaac aatagctagt atctttatca cctgcaataa tgacatttgc
    90961 ttgaatagct aataattttt gacgaagata agaaatataa acccaaacaa tagaagtatc
    91021 ataatcttct tggtctgacc aaacatgttg gtaaagtgtt ttagtatcca agtactttcc
    91081 ttgatttaac attaaaaagg ccattaattt accttcttta gaagctaatc gtatagcatt
    91141 accggcactc aattcttgct cattaatatt taatgtgaca ccagcaaatt gtaatacctg
    91201 aggagtaaaa ctttctactc gtctttccat cgaccttaat ctagctaaaa gttcttttaa
    91261 tgagaaaggt ttagtcagat aatcatcagc tcccgcatct agtccggtaa cacggtcatt
    91321 aatttctgcc atagccgtca gcataataat atgtgagcaa tttcctgaag cgcgaatctc
    91381 ctttaaagcc tcaatgccag acttaatcgg catcatgata tctaaaatca taatatcata
    91441 tgcattgtct ttagctttat caattgcctc ttgaccgtta aaaaccacat caacgtcata
    91501 accttgatga gtcatggcag ttgtcaaaac attagacatc tgccattcgt cttcagctaa
    91561 caaaattttc atggttactc ttcctccgtc gtttcttgaa tcaattgacg aatggtttgc
    91621 atggtaacat cacaagatgc caactcgtct gcacaacgct ttaactctct tgtaatcatt
    91681 tctgcattag caacttgatg tttgtacttc atttgatgtt ccaagctagc ccaagagtct
    91741 tgagcaatgg ttcgcaactg cacttctata aaataacatc cttttttttc ccctaaaata
    91801 tctggaaaat gtgtttctaa ttccaaaatg agatgatatg atctatagcc attaggcttg
    91861 gcatttaaaa tataatcttt ttcagtgtta actgacatac caggaatgct tttgagcaag
    91921 tctaccatcc gataaatatc atcaataaaa ccacaaataa tgcgaatacc gatactatct
    91981 ttaatgattt ttaacgcaga tttgcttgtt agaggaagct gtttgcgttg acatttttca
    92041 atcatcgaag cttccgattt aatacgggat gtaaagtgtt catatagttt aaaccctgtt
    92101 tcttttttgc ttttgatatt ctcagcaata atcacatctg ttattgtctg tagtaccaac
    92161 ggcaagtaca cttcaaatcc gctatatata gagctggtag aataatgttc tagtctttct
    92221 ttcatacgct tattataaca aattttctca acaaatgctt aaatctctac
//
LOCUS       DATTYN010000006        61680 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.06, whole genome shotgun sequence.
ACCESSION   DATTYN010000006 DATTYN010000000
VERSION     DATTYN010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61680
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.06"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            179..364
                     /locus_tag="VB649_000553"
     CDS             179..364
                     /locus_tag="VB649_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669528.1"
                     /translation="MSFEIFTLIIGWKLVGYRVMECGSSFKQGDYRLVVHICLLNVRD
                     EMLSQQGHEDKADWPEP"
     gene            1002..1310
                     /locus_tag="VB649_000554"
                     /pseudo
     CDS             1002..1310
                     /locus_tag="VB649_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284415.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
     gene            1365..1577
                     /locus_tag="VB649_000555"
     CDS             1365..1577
                     /locus_tag="VB649_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-diphosphocytidyl-2C-methyl-D-erythritol
                     kinase"
                     /protein_id="HEP1669529.1"
                     /translation="MVAAIEAGNYNDGILTEMNNLLEDIFIAKRPFIQKIKEKTLQAG
                     AATTLMTGSGPTVFALCQTEKQTIIV"
     gene            1687..2130
                     /locus_tag="VB649_000556"
     CDS             1687..2130
                     /locus_tag="VB649_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEP1669530.1"
                     /translation="MGTLEKKLDNLVNTILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQQRLTNTDLAKALNISQAAVTKAIKSLVKQDMLAGTKDTVDARVTYFELTELAK
                     PIASEHTHHHDETLNVYNRLLQKFSAKELEIVDKFVTVFAEELEG"
     gene            2134..2853
                     /locus_tag="VB649_000557"
     CDS             2134..2853
                     /locus_tag="VB649_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEP1669531.1"
                     /translation="MRYISVKNLSFQYESEPVLEGITYHLDSGEFVTMTGENGAAKST
                     LIKATLGILQPKAGRVTIAKKNKDGKQLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFRHLNKHDEEHVQASLEAVGMWENRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHQHGKSVLMITHDPEEVKAYADRNIHLVRNQKLP
                     WRCFNIHEAETDDEKGGHGHA"
     gene            2846..3703
                     /locus_tag="VB649_000558"
     CDS             2846..3703
                     /locus_tag="VB649_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEP1669532.1"
                     /translation="MLDILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLMSDTLS
                     HVSLAGVALGVVIGISPTITTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLALS
                     LIIMSKSHSSSSMSLEQYLFGSIITISMEQVVALFAIAAIILILTVLFIRPMYILTFD
                     EDTAFVDGLPVRLMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKT
                     VILLGIVIGFSGMLSGIFLSYFFETPASATITMIFISIFLLVSLGGMLKKRLFINALK
                     RGQGPNFLD"
     gene            complement(3657..4040)
                     /locus_tag="VB649_000559"
     CDS             complement(3657..4040)
                     /locus_tag="VB649_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEP1669533.1"
                     /translation="MTECIFCHQLKANQLLTQSQYFKVVFDIDPIQKGHLLLISKDHY
                     TSLTQLPKEVRYDLIDLQAALVAKLEQHLSISGVTSVSNDKELMDEGTHFHLHLIPRL
                     TNDSFWEGITINQENWDLAPFLKHL"
     gene            complement(4091..5347)
                     /locus_tag="VB649_000560"
     CDS             complement(4091..5347)
                     /locus_tag="VB649_000560"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEP1669534.1"
                     /translation="MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIK
                     GQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIETQFNAARHERLAQKTLAREVVTLVHGEKAYKQALNITEQLFAGNIKNLSANEL
                     KQGLSNVPNYHVQSEDSLNLVDMLVTADISPSKRQAREDVQNGAIYINGDRVQDLDYQ
                     LSNDDKIDDQLTVIRRGKKKYAVLTY"
     gene            5439..7751
                     /locus_tag="VB649_000561"
     CDS             5439..7751
                     /locus_tag="VB649_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEP1669535.1"
                     /translation="MRYFMVKWNTKQKRISHQRLGLLDLGPVLLRTLRLLSNFFYIVI
                     FLFGMMGFGMAFGYLASQIESVKVPSKESLVKQVESLTMISQMNYSDNSLISTLDTDL
                     LRTPVANDAISENIKKAIVSTEDEHFQEHKGIVPKAVFRATLASVLGFGEASGGSTLT
                     QQLVKQQVLGDDPTFKRKSKEIVYALALERYMSKDNILCDYLNVSPFGRNNKGQNIAG
                     VEEAARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLSTGQLKSEKDMAYGIKRQQN
                     VLYNMYRTGVLSKKEYEDYKAYPIQKDFIQPGSAIVNNHDYLYYTVLADAKKAMYSYL
                     IKRDKVSSRDLKNDETKAAYEERALTELQQGGYTITTTINKPIYNAMQTAAAQFGGLL
                     DDGTGTVQMGNVLTDNATGAVLGFVGGRDYALNQNNHAFNTVRSPGSSIKPIIAYGPA
                     IDQGLMGSASVLSNYPTTYSSGQKIMHADSEGTAMMPLQEALNTSWNIPAFWTQKLLR
                     EKGVDVENYMTKMGYKIADYSIESLPLGGGIEVSVAQQTNAYQMLSNNGLYQKQYIVD
                     KITASDGTVVYKHENKPIRIFSAATATILQELLRGPITSGATTTFKNRLAAINPWLAN
                     ADWIGKTGTTENYTDVWLVLSTPKVTIGGWAGHDDNTSLAPLTGYNNNSNYLAYLANA
                     INQADPNVIGVGQRFNLDPGVIKANVLKSTGLQPGTVNVNGHTFSVGGEMTTSLWSQK
                     GPGAMTYRFAIGGTDADYQKAWGNFGFRKN"
     gene            8015..11581
                     /gene="rpoB"
                     /locus_tag="VB649_000562"
     CDS             8015..11581
                     /gene="rpoB"
                     /locus_tag="VB649_000562"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEP1669536.1"
                     /translation="MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVR
                     NTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVG
                     RYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKF
                     VYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGTVTNEIV
                     WLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIAD
                     GPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK"
     gene            11672..15295
                     /gene="rpoC"
                     /locus_tag="VB649_000563"
     CDS             11672..15295
                     /gene="rpoC"
                     /locus_tag="VB649_000563"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEP1669537.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQ
                     EYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFN
                     KSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDNQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLEINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSA
                     EAE"
     gene            15447..15812
                     /locus_tag="VB649_000564"
     CDS             15447..15812
                     /locus_tag="VB649_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEP1669538.1"
                     /translation="MYQVIKMYGDWEPWWFIDGWQDDIIDEQQFSDWQEALDYFNQEW
                     QRMKAIFPSYHSQKNLLATFWEKEDKRWCEDCDEDLQQFHSLLLLKNKDIVPSNNYIP
                     EFEQRNDSPQVAYLCKLNL"
     gene            15898..16836
                     /gene="tadA"
                     /locus_tag="VB649_000565"
     CDS             15898..16836
                     /gene="tadA"
                     /locus_tag="VB649_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEP1669539.1"
                     /translation="MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVD
                     VYQSDRMAPLISHFKFVSGMIVGEKRRCQVGSCDYKLSKDKQLSLRLSSVGDYRGQES
                     LVIRLLHHQNKSVHYWFDGLTKVANQVGGRELYLFAGPVGSGKTTLMYQLISSYHQEA
                     QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAV
                     IRASLTGAMVFSTVHAKSISGVYVRLLELGVTKAELSNCLALIAYQRLLNGGALIDST
                     QNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII"
     gene            16820..17806
                     /locus_tag="VB649_000566"
     CDS             16820..17806
                     /locus_tag="VB649_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEP1669540.1"
                     /translation="MKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYV
                     LKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRR
                     KTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILL
                     FGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDI
                     MAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELE
                     IYAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF"
     gene            17808..18134
                     /locus_tag="VB649_000567"
     CDS             17808..18134
                     /locus_tag="VB649_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEP1669541.1"
                     /translation="MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKD
                     RVTETGNAAVVKLVENQAELYELSQGSKPSLGQLKADGSITEKQEKAYQDYYDKHKNE
                     KARLSN"
     gene            18109..18537
                     /locus_tag="VB649_000568"
     CDS             18109..18537
                     /locus_tag="VB649_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEP1669542.1"
                     /translation="MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEH
                     LFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTEGNSLTVPKSITVNHPYRLVIDQ
                     MGGNHSLAKIIFDMTDRCFKYQFYLGSGNYQKTSQSLHSP"
     gene            18542..18778
                     /locus_tag="VB649_000569"
     CDS             18542..18778
                     /locus_tag="VB649_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEP1669543.1"
                     /translation="MIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQT
                     RTKEMTLNGCHITILRTDRYISIHDDEGEVMKIE"
     gene            18771..19205
                     /locus_tag="VB649_000570"
     CDS             18771..19205
                     /locus_tag="VB649_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEP1669544.1"
                     /translation="MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYL
                     ARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEKGKKVLAFGQFKSHDFRKSASNG
                     KGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD"
     gene            19189..19515
                     /locus_tag="VB649_000571"
     CDS             19189..19515
                     /locus_tag="VB649_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEP1669545.1"
                     /translation="MPFKTNLKAGILLYAMFMASIFLLVLQVYLSQVTALHKEYQAQT
                     DYVKARLIAEIVYQDHRYKASNPVFFKGGQVICRERKERWMLIVKLDQQRQYQFEYLK
                     PKQYSQ"
     gene            19613..20566
                     /locus_tag="VB649_000572"
     CDS             19613..20566
                     /locus_tag="VB649_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP1669546.1"
                     /translation="MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEG
                     ASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQTEQLQANHQFTPDAIGFILLYLL
                     EQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
                     AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSL
                     KYLKKDGFAIFLAPVNLLTSPQSQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIV
                     LQKQTDHPMETFVYPIRDLKRAENIHDFMENFKKWKLSNVN"
     gene            20625..21821
                     /locus_tag="VB649_000573"
     CDS             20625..21821
                     /locus_tag="VB649_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEP1669547.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEEVLAQGIIERIGLKDSISTV
                     KYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVV
                     VNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYH
                     GKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSG
                     VSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVE
                     RLKNTK"
     gene            22007..22249
                     /locus_tag="VB649_000574"
     CDS             22007..22249
                     /locus_tag="VB649_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669548.1"
                     /translation="MYVFIEPNNLKDYLITVYDERNRAIRKQTQVYCFYLMIVLFVAL
                     FFFFPCLILRDLVSYKLPLIFAYLYLIIRSLVAKKM"
     gene            complement(22398..23168)
                     /locus_tag="VB649_000575"
     CDS             complement(22398..23168)
                     /locus_tag="VB649_000575"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEP1669549.1"
                     /translation="MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLT
                     LPYAMSHQDLIDQVDLVILGIKPQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD
                     LPLLRIMPNMNAQILQSSTALTGNALVSQELQARVRNLTDSFGSTFDISEKNFDTFTA
                     LAGSSPAYIYLFIEALAKAGVKNGMPKAKALEIVTQTVLASASNLKTSSQSPHDFIDA
                     ICSPGGTTIAGLMELERLGLTTTVSSAIDKTIDKAKSL"
     gene            complement(23216..24283)
                     /gene="pepA"
                     /locus_tag="VB649_000576"
     CDS             complement(23216..24283)
                     /gene="pepA"
                     /locus_tag="VB649_000576"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEP1669550.1"
                     /translation="MTDLFSKIKEVTELDGIAGYEHSVRDYLRTKITPLVDRVETDGL
                     GGIFGIRDSKAEKAPRILVAAHMDEVGFMVSDIKVDGTLRVVGIGGWNPLVVSSQRFT
                     LYTRTGQVIPLISGSVPPHFLRGANGSASLPNIENIVFDGGFTDKAEAESFGITPGDI
                     IVPQSETILTANQKNIISKAWDNRYGVLMITEMLEALKGQDLNNTLIAGANVQEEVGL
                     RGAHVSTTKFDPELFFAVDCSPAGDIYGNPGTIGDGTLLRFYDPGHVMLKDMRDFLLT
                     TAEDAGVNFQYYCGKGGTDAGAAHLQNGGVPSTTIGVCARYIHSHQTLYAMDDFVEAQ
                     AFLQAIIKKLDRSTVDLIKRY"
     gene            24739..25029
                     /locus_tag="VB649_000577"
     CDS             24739..25029
                     /locus_tag="VB649_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEP1669551.1"
                     /translation="MRDMSKKKIGMISGIFGFSLAIGLGIVIKDYCQDRKRRQMTRDL
                     RTFFSPLGQIEVLYINPCQVKQDYISGGVVMSNGKQYQFTYHSRQISFEEDK"
     gene            25029..25346
                     /locus_tag="VB649_000578"
     CDS             25029..25346
                     /locus_tag="VB649_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEP1669552.1"
                     /translation="MIRPTSYESLAALVEKEDKLVLFFTADWCPDCQFIYPIMPEIEA
                     ELTDMTFVCVNRDQFIEVAQKWDIFGIPSFVVIEKGQEVGRLVNKMRKTKTEIMHFLA
                     AYQ"
     gene            25364..25990
                     /locus_tag="VB649_000579"
     CDS             25364..25990
                     /locus_tag="VB649_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEP1669553.1"
                     /translation="MIFAYNKEQVGDVLMVILQDTKDIKRQVERKGKVARVFAEESGK
                     TLAWNIFEASSLITIEGNGQIFLTDEDLARLNAELAKEGFSERLEPTVGPVFVVGQIV
                     EMVAHPDSDHLNICQVAIGEDQTVQIVAGAPNAALGLKTIVALPGAIMPNGSLIFPGK
                     LRGEESYGMMCSPRELALPNAPQKRGIIELDESAVVGEAFDPAKHWKG"
     gene            26141..26536
                     /locus_tag="VB649_000580"
     CDS             26141..26536
                     /locus_tag="VB649_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP1669554.1"
                     /translation="MYNKVIAIGRLVAKPELVKTATDKHVARLSLAVNRRFKNASGER
                     EADFISVVVWGKLAETLVSYASKGSLMSIDGELRTRKYNKDGQVHYVTEVLCQSFQLL
                     ESRAQRAMRENNVTNDLVDLVLEEDTLPF"
     gene            complement(26796..27437)
                     /locus_tag="VB649_000581"
     CDS             complement(26796..27437)
                     /locus_tag="VB649_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HEP1669555.1"
                     /translation="MLIVLAGTIGAGKSSLAAALGEHLGTDVFYEAVDNNPVLDLYYQ
                     DPKKYAFLLQIYFLNKRFKSIKEAYQADNNILDRSIFEDELFLKLNYKNGNVTKTELD
                     IYQELLANMLEELEGMPKKRPDLLIYIDVSFDKMLERIEKRGRSFEQVDGNPSLEQYY
                     HQVHGEYPTWYEDYKVSPKMKIDGNSLDFVQKPQDLATVLKMIDTKLKELHLL"
     gene            complement(27457..28434)
                     /gene="dusB"
                     /locus_tag="VB649_000582"
     CDS             complement(27457..28434)
                     /gene="dusB"
                     /locus_tag="VB649_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEP1669556.1"
                     /translation="MIKLNSSFRIGDVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDENEHPMSIQLFGGDAEGLKRAADFIQTNTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIVKEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAESAGVSALAMHGRTREQMYTGTCDHETLARVSKAITKIPFIGNGDVRSVQDAK
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGQELPDLPFAKKLDIAKDHLKRLIN
                     LKGETIAVREFRGLAPHYLRGTAGAAKVRGAVSRAETLAEVEAIFETVR"
     gene            complement(28421..29293)
                     /gene="hslO"
                     /locus_tag="VB649_000583"
     CDS             complement(28421..29293)
                     /gene="hslO"
                     /locus_tag="VB649_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEP1669557.1"
                     /translation="MDKIIKSIAQSGAFRAYVLDSTETVALAQEKHNTLSSSTVALGR
                     TLIANQILAANQKGDSKITVKVIGDSSFGHIISVADTKGHVKGYIQNTGVDIKKTATG
                     EVLVGPFMGNGHFVTIIDYGTGNPYTSTTPLITGEIGEDFAYYLTESEQTPSAIGLNV
                     LLDENDKVKVAGGFMVQVLPEASEEEIARYEKRLQEMPAISHLLASKNHVDALLEAIY
                     GDEPYKRLSEEPLSFQCDCSRERFEAALMTLPKADLQAMIDEDKGAEIVCQFCGTKYQ
                     FNESDLEAIINDKA"
     gene            complement(29440..30933)
                     /gene="rofA"
                     /locus_tag="VB649_000584"
     CDS             complement(29440..30933)
                     /gene="rofA"
                     /locus_tag="VB649_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047149466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RofA"
                     /protein_id="HEP1669558.1"
                     /translation="MIEKYLESSIESKCQLIVLFFKTSYLSITEVAEKTGLTFLQLNH
                     YCEELNAFFPGSLSMTIQKRMISCQFTHPFKETYLYQLYASSNVLQLLAFLIKNGSHS
                     RPLTDFARSHFLSNSSAYRMREALVPLLRNFELKLSKNKIVGEEYRIRYLIALLYSKF
                     GIKVYDLTQQDKNTIHSFLSHSSTHLKTSPWLSESFSFYDILLALSWKRHQFSVTIPQ
                     TRIFQQLKKLFVYDSLKKSSRDIIETYCQLNFSAGDLDYLYLIYITANNSFASLQWTP
                     EHIRQCCQLFEENDTFRLLLNPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPE
                     TNLFISPYYKGNQKLYTSLKLIVEEWMVKLPGKRYLNHKHFHLFCHYVEQILRNIQPP
                     LVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQL
                     IPFVQHELTKGIAVAEISFDESILSIQELIYQVKEEKFQADLTKQLT"
     gene            31165..32832
                     /gene="sfbI"
                     /locus_tag="VB649_000585"
     CDS             31165..32832
                     /gene="sfbI"
                     /locus_tag="VB649_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein SfbI"
                     /protein_id="HEP1669559.1"
                     /translation="MVSSYMFVRGEKMNNKMFLNKEAGFLAHTKRKRRFAVTLVGVFF
                     MLLACADAIRFGQVAYAADEKTVPNRINSNPEFPWYGYDAYKGFEARYHDLKVNLKGS
                     KEYQVYCFNLKRSFPRRTHSITNNFYKKIVGSGSVFKSYAENPRVLDENLDKLEKNIL
                     NVIYNGYKSNANGFMNGIEDFNAILVTQTAIWYYSDSSPASATAVEKMWDREVKDGDI
                     SLEQVKLMREALKKLIDPNLEATAVNKIPSGYRLNIFESENEDYQNLLSAEYVPDSPP
                     MPGEVPKEESPKEENPKIPDLDGREIPEVPQEPSDPVIPPVILDGEEVPEVPSESLEP
                     ALPPLMPELDGEEVPEKPSIDLPIEVPRYEFNNKDQSPLAGESGETEYITEVYGNQQN
                     PVDIDKKLPNETGFSGNMVETEDTKEPEVLMGGQSESVEFTKDTQTGMSGQTTPQVET
                     EDTKEPEVLMGGQSESVEFTKDTQTGMSGFSETAIVVEDTRPKLVFHFDNNEPKVEEN
                     REKPTKNITPILPATGDIGNVLAFLGILILSVLSIFSLLKSKQNNKV"
     gene            34050..35759
                     /locus_tag="VB649_000586"
     CDS             34050..35759
                     /locus_tag="VB649_000586"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HEP1669560.1"
                     /translation="MKLSKKLSKKLSKKLLYSAMAFTMLTSATVAPVAQIIPSSTVRA
                     ETLQDRTQKTIPEATEVVITKLQADDYNDDVKPNGKANENGLPINNLGELGRNVKPLS
                     DVTFVAYKIPEGIAEEKVKELKTKQTVVDVENYLNAQNLKIEKTVLTKTDGNGQTTFT
                     VQKSSYGKYFVVEDMTATGTPETISKAYAVPFTLELPISASDGTGYLTKVNIYPKNVT
                     SSLPKPGKDVKELGLNHSSYNIGERFSWFLKGTVPKNMLDYEKYSFTDTLDSQLDFIS
                     VKSVKYGSQILEKNNDYTLSEPTAQNRTLKVELTEAGIKKVAGLYPDRQEVLDTEIEA
                     IKENTDQKPFLEVEFETNINSTVILGKPVTNEVKIEFDNKPDKIAKPVTTPPSDNPEV
                     HTGGKRFVKVAAGNDATKLGGAEFDLLTEANQPINWTAELIRANNKSEYIVGTPQEGQ
                     PVKLKSDTDGSFEIKGLAYAIDAEATGAGVKYKLKETKAPAGYVIPEAPIEFAVNQTS
                     YNKTPTTIDVDKADAEPQKVENNKRPEIPNTGGIGTAIFVVLGIVLMVVATKGMRSHK
                     EEN"
     gene            35842..36774
                     /locus_tag="VB649_000587"
     CDS             35842..36774
                     /locus_tag="VB649_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP1669561.1"
                     /translation="MQKLLKYLCSFGVVLGLLLGFPGQVLAQGDQAQLTVVHLESRDV
                     DRPNPQLDLAPSAGKPVEGITYRLYQLKLGREAQPISYWEKLTLQALEEQAQTVFEAK
                     TDAQGHAAFLQLPTGIYYGVAVENQQRQAGIAGFLVDLTGDTGYVKTVYPKVIWPTGG
                     LHLIKYGVDGQTKVPLAGVRFELYEDNGFKPLRVKDGLHSYDLDAKTTLITNQEGQLK
                     VAGLLAGNYYLKEVATAKGYRLKTDAISFQVQAHQTKTVSVDNQKEPPPPVTPWDWIP
                     RTGEAQALTLIVLGLILMLLALFYYQKHRQEGND"
     gene            36752..37627
                     /locus_tag="VB649_000588"
     CDS             36752..37627
                     /locus_tag="VB649_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEP1669562.1"
                     /translation="MVKRATISMETSKKKVELRVWLSRLVFLAGFLVLAFPIVSQVLY
                     YQASRADINAFKQAVTKIDRTEIKRRLELARAYNASLSGGTNQTTKPVLKDPYSDHQK
                     KAGRAEYSRMLEVREQIGHVTIPKINQDLPIYAGSGEENLQRGVGHLEGTSLPIGGPS
                     THAVLTAHRGLPTARLFTDLDKMRRGDRFYIEHLGGKLAYQVDSIKVITPDRLDELYL
                     VPDKDYMTLLTCTPYMINSHRLLVRGKRIPYKESLKQKDQQIGQRHQLATYGFIALGL
                     TLVLGLLWYRKRQKK"
     gene            37641..38498
                     /locus_tag="VB649_000589"
     CDS             37641..38498
                     /locus_tag="VB649_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEP1669563.1"
                     /translation="MKQKVNQLYQLIATNKLRSVLFILGILVVLFPIVSQASYYLASH
                     QQINQFEHKAAVIDRSAIERRISLAKAYNDAISRHPSLSDPFTSKEKAGLREYARMLE
                     VNEQIGHVAIPKIGVDLPIYAGTSAAILEKGSGHLEGTSLPIGGKTTHAVLTAHRGLP
                     TARLFTDLDKVKKGDYFYVTNLKGTLAYQVDRIMVIEPSQLDAVSIEEGKDYVTLLTC
                     TPYMINSHRLLVRGVRVPLTSRQAKKESLTAVRPYQYYRWLVYLAIAVLIILVMIVAK
                     YYQKTNKSS"
     gene            38568..43706
                     /locus_tag="VB649_000590"
     CDS             38568..43706
                     /locus_tag="VB649_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding adhesin SdrG C-terminal
                     domain-containing protein"
                     /protein_id="HEP1669564.1"
                     /translation="MTNKTLHKVLVKLAAVLAILFLVLPTGLTAVTVLAEQINTENLI
                     PVETAAGEILKESDLDFEQAIPTSGEALKDSSASWIQLTYNKVNQNLAKQDLFLRLPQ
                     GMTIEGIGQDQKLDVKTISVPKDLDLDEAASTINNTNIITGFEKIGEQDYKLSFAATS
                     KTLNLVFKVKGTSLNEKRELQLSDKQNLNQTSFTKKLGLGIAKSDDRTSANDTTTRPS
                     IQPRAATARETTGNQDISANLTTSNAQLNLEDKDKNNIYDVEAPDSFMFRATLSLLDS
                     RYIVPGNYFELKLSDTIHYNMLNPTDINFPYLTQDGKVIAVPELVQDPPVDGLLRATG
                     KIVRYRFTDQVQGLDSLTMTLNLGHSVNPNVVQNNDKYDFSYQIGGHIIKQSYDVQYG
                     KPKENGNLNVHQRLTYTDSKQNLKASSLIYVNPKQTPQYAGKQTLSILRNPKTYTISE
                     QTVPNLLELNNQTSIKVYKLKDSKGVTDAVNLDKQYLEEVINPIITKSDGKIEVSFNY
                     TQGETSAYVVAVETSLQQEGSQPVFIAQNSNLTSASTRKKVSETDATATVGSGGSASG
                     DQTPKGTLYLNKVDTNHKHLANATFTLSGNTTAGQFLYRTLITDTKEVSFSDLPPGSY
                     LLKETTAPSGYQQITTPWTVTVDDKGKVTVTGNEADTQKVPEEAEVVILWESTKWNYG
                     NVQFYKDRFKELVDSVGNQNAKYTLIRYSGDTSDSAQVINQSVSSAEFNKILNSETLT
                     ASTMTNRKGMLKAYQLALQQFQASTNKRKYLLQLTNYPIYPGYREEKDFMSQSQTSFD
                     AMKSLGVVPYLLVERDPYANRNTYLDPKAEASSFGAFYPSDNIKVVWSNNSSGLFTPP
                     TNTNYTIQIQSIGSAIKQQIPESVLTVINRASGKFSINKIDEAKKGLAGATFTLSKRT
                     TVAVNHQVQGAFTPVSKETTAGRTTLTFDNLKPGVYDLKETKAPNAYVLDPKTYVVVV
                     QNSGKTTIVDEANFKEADYPMADNTSQFDYPTKDIANKPNKIVFTKIGDGGKSLSGAE
                     FELRKGNEKVQTTTSGADGKVTFSKLLPGTYEVWETRVADSAYQLPQEAVATFEVKAD
                     GTFSEPMGRLFRKNIAQNNRYEIRNELVNKKTGNQKIKVIKKDELTDLPLPNAKFQLE
                     ASDGTIYTKTTDVKGEIVFEKLPYGQYILTEIEAPSGYVLDPTPHKINLTEVDSPETE
                     VVAGRNATQPTVAPTARAALAAPVAEPVTGKNVSDQISIKELDITSSNEDTPRLVRPN
                     HGENIVMRAGFTINPGSDIKAGDFFTLTLPNTIDPFGVSAPENVDFRILGPLGTLALG
                     TYDSSTHTITYKFTDYITRYTVSSFSTISPFFIDRDRVKTNQDIDLFLKVGQVSSTSY
                     HFTVDYNPYYGTADTNNPVNVGSMITRLNQDTGDFVNYIYVNPAGQTLEQATLTFTGR
                     GSTRIDANTRVQLFEVTNPKLQMPPSWGIQDETLREVDPANYQLIKENGRFTINFYND
                     LLYGRSYIVKVSGKSDKNDPDPIHTSAILTQRYFNDYPYYTPSGRYIPYGPYTESFTF
                     TAEVVKKSGESNADGSVVVRLSNRKNYIDFMKSNSQGTPLEATFELRKKATNDTVTVG
                     TPVISDKTTGKFYFEGLSPGDYEVWETKAPDGYTKPVEAVATFKVTDEGEIVDKSLED
                     GRIINYRRPELPATGGPGIFVYLFIGSAMCLVAIFWDHSFRFTK"
     gene            complement(43885..44550)
                     /locus_tag="VB649_000591"
     CDS             complement(43885..44550)
                     /locus_tag="VB649_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669565.1"
                     /translation="MKRYNKYLFTSLLAASMLFSSYKSVHAHDNIDEKGKVHLYWQGN
                     YYVDNYVDYTKTLVDNNNSIEWTVTFNSAKEQWVYPDFSVFLPKGVKAPKEITYEHHY
                     WDGTVDSKTRRNTKWHYDWESQQTNFNQEFDKFPGYTGWSPSLDKFYKLKNEGKFSHV
                     LVDTYGRQSHTYFSHKMVWKFKTELEEDYKNKWDKLPFIAGIKQNNPLAASFPSYKGE
                     FGE"
     gene            44905..46311
                     /locus_tag="VB649_000592"
     CDS             44905..46311
                     /locus_tag="VB649_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="short-chain fatty acid transporter"
                     /protein_id="HEP1669566.1"
                     /translation="MNNIKTKKRFMDRYIDGFMKWMPESLFICFILTFLVVTMSVLMT
                     DSPFIGTEKTGGIIYGWVNGFWGLLSFAMQMTILLATGNAVASSPPAHKMFKSRAKLP
                     QTRTQIFIFSIVVGSIFGFLHWGLGMMVAIVFGKELLVQARQKGIKVHTPLFVATLFF
                     TFLPATSGLSGAAVLYSATPDYLRNSVADAYKQVVPESVPLTESVLNLPFISLLVVCM
                     LVPLCFALLAHPKDETKIMELDDEIYHHSLDTASHVVIARNTPAEKMNASRLVMYLVG
                     GAIVSYSLYHFSVVGLSGLDLNSFNFLFLGLGLLLCGQQGPEYYGSLFKDGVMSSWGL
                     VLQFPFYAGIFGIIQSTGLGLEISHFFVAISNGTTWPVFAYLYSALLNIAVPSGGSKF
                     VIEAPYIVPATIEVGNDLGKILQAYQLGDATTNLIVPFWALSYLSNFKLKFNQIVAYT
                     IPCVLVVTGIAIIYLFVF"
     gene            complement(46380..47291)
                     /locus_tag="VB649_000593"
     CDS             complement(46380..47291)
                     /locus_tag="VB649_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP1669567.1"
                     /translation="MNISSLAYFIEIVNCDFNLTKAAQKSHISQPALSSYIKTIEKEE
                     GVVLFQRQKGRLVGLTSVGEHFFENAKVVIASHEQLMADLRSESKKYKGEISIGIPQL
                     ISGIVFSELIPKLIEENPEVKFHIVETGAYELQKKLFLKEVDFAILLTPTTLDATIAD
                     IDILLRDQLCLYMSHKTFQETFDSNPNISIKALHRQNLVTFDKTFMINHQLTTLFEEA
                     NSLPVVKCYSASWDFLLNCTRYSSYLTILPRPITHFAHMDGLVEVQLTEHPKWEVVLA
                     SLKHNKTSHLKHYIKHTILDYFTNQRF"
     gene            47412..48596
                     /locus_tag="VB649_000594"
     CDS             47412..48596
                     /locus_tag="VB649_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEP1669568.1"
                     /translation="MTKEVVITSAYRTPIGNFGGVFKSLSAVDLGVTVVTKILADTGL
                     KSDAIDEVIFGNVLHAGLGQNVARQVALNAGLSYDTPAFTIDMVCGSGLKAVELGAQK
                     IQTGNADIVLVGGTENMSQAPYVLQGQRWGSRMGDSKVVDTMLKDGLSDAFAGYHMGI
                     TAENIVQQYGLTREEQDAFAADSQRKAQLAIEKGRFKEEIAPVTIPQRKGEPLLIDQD
                     EYPKFGTTVDKLAKLRPAFIKDEGTVTAGNASGINDGAAAILLMSKEKAEELELPILA
                     KITGYASAGVDPSIMGCGPIPATKKALAKAQLTIDDIDLIEANEAFAAQALAVSRDLG
                     FDNEKVNVNGGAIALGHPIGASGARILVTLLAEMAKRDVRHGLATLCIGGGQGQSIIV
                     TR"
     gene            48608..49267
                     /locus_tag="VB649_000595"
     CDS             48608..49267
                     /locus_tag="VB649_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEP1669569.1"
                     /translation="MKENKRIAIAEAISHIKDGDTIMVGGFMANGTPEALIDALVDKG
                     TKDLTLICNDAGFVDRGVGKMVANHQFKTIYATHIGLNKEAGRQMTAGETTIELIPQG
                     TFAEKIRIGAYGIGGFYTPTGVGTLVAEGKETKTIKGKTYLLEYPFEADVALIFANKA
                     DEMGNLQYSGSENNFNQLMAACAKTTIVQAREIVPVGTIQPECVHTPHIFVDYIVKEG
                     V"
     gene            49270..49917
                     /locus_tag="VB649_000596"
     CDS             49270..49917
                     /locus_tag="VB649_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEP1669570.1"
                     /translation="MAVALSKEEIQNRIAKRVAKELEDGTLVNLGIGLPTKVANFVPE
                     EMTVYFQSENGFIGLGPKSDDPNSTIVNAGGQPVTVYPGASFFNSADSFGIIRGGHVD
                     LTVLGALEIAENGDIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKHKLLKE
                     CTLPLTAKGVVDLIITEMGMFKVTPDGIQVIEISEGFTFDEVQAATGVPLSIAEG"
     gene            complement(50039..50719)
                     /locus_tag="VB649_000597"
     CDS             complement(50039..50719)
                     /locus_tag="VB649_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP1669571.1"
                     /translation="MDKETLNYWKTVITFLHDVLGDNYEIILHVIDKNDIYIGELVNS
                     HISGRSKQSPLTTFALDLITNKVYKEKDFVTNYKAIVSPQHKEVRGSTFFIKDKKGNL
                     EGMLCINLDISAYQGVARDLLKLVNLNLEHFIPTAKEPKTVTPQPEEAVEILTSNIQD
                     IIGQIIDPSLLRHNVHLSQDVKIDIVAKLYEKGVFQLKGAVSKVADILCISEPSVYRY
                     LKKIEADQ"
     gene            50893..51258
                     /locus_tag="VB649_000598"
     CDS             50893..51258
                     /locus_tag="VB649_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEP1669572.1"
                     /translation="MKSYPEPMGPYSTYTIEGHFLYTAGQLPLNPVTGQLSDGFEAQC
                     RQVFVNLQSILAEQKLDLNHIYKLNVYLTDVTNVEILNHVMTDLFEEPYPVRTAVQVS
                     ALPLQALIEVEAVARVKQL"
     gene            51295..52314
                     /locus_tag="VB649_000599"
     CDS             51295..52314
                     /locus_tag="VB649_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEP1669573.1"
                     /translation="MDIIIGTSLLILVLAIFSLFNYKAPHGAKAMGALASAACASFLV
                     EAFQDSFFGKVLGFQFLSEVGGANGSLSGVAAAILVAIAIGVSPGYAVLIGLSVSGTG
                     IIPGFVAGYVVSFLIKWMEKNIPGGLDLISIIIVGAPLTRFLAQLITPVINSTLLTIG
                     DILTSSANSNPIIMGMILGGTIVVVATAPLSSMALTAMLGLTGIPMAIGALSVFGSSF
                     MNGVLFYRLKLGERKDNIAFAIEPLTQADVTSANPIPIYVTNFVGGAACGVLIALMKL
                     VNDTPGTATPIAGFAVMFAYNPVAKVLITALGCIIISLIVGYIGGSVFKNYRLVTKQE
                     LQARN"
     gene            52769..53089
                     /locus_tag="VB649_000600"
     CDS             52769..53089
                     /locus_tag="VB649_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669574.1"
                     /translation="MNTLLSLMNSIEQEARTIYDSYDAKKKALADKKEEELKQLFLEY
                     EQETQLLLEAKREVFFEANRQEQKASKKRLATQQLALHAILEEHKLTVVRELVDKVVE
                     TYGH"
     gene            53079..55079
                     /locus_tag="VB649_000601"
     CDS             53079..55079
                     /locus_tag="VB649_000601"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEP1669575.1"
                     /translation="MAISQMKKLAMVFEKDYLDLVLKTLQQSQLVEVRDMKQLKHWQD
                     AFNKGNVKLPQIVQYDLTHQKPLLDDEALQYLLQSQQELENGLASLSAFLPSIGKLTA
                     LRQKTPSLSFKQFEERHRQQAAQTALKMMSQKIERLEQLQSKIDQLTEYCQELEKWRS
                     LTVLPQDLAQFHFLSARVGTIPSTANDHFYHQLKQHKGLFIEEVYHTEFEYGLVLFWQ
                     AQDTIHLQKYQFKPLLYKEQLLPSEQLRINKELLTNWLAEKDSLLKELRQSQKILAQL
                     QVEIDYVLSQYQRQQTKKQLLGTRHLIALEGWIEADSVNQLKGLMTKTLGDMFYLDSY
                     DVTPDDWEDVPIKLRNHRYIAPFELVTEMYALPKYQEKDPTPFLAPLYLTFFGMMVAD
                     LGYGLLLYAVTLAALVFFNLQKTSKRLVTFFNILAISVALWGLIYGSFFGFDLPVALL
                     STKTDVITILVVSLLFGFVTLIFGLLLGAWQQVRMKAYATAYTSSLAWTFILLGLLLF
                     ILGKNVSGLAYLSVIGKWLALGNAFGILVVSLLKSKSLLGLGSGLYNLYGISSYLSDL
                     VSFTRLMALGLSGASIGAAFNMIVGIFPPVTRFTVGIFIFILLHAINIFLSMLSGYVH
                     GARLIFVEFFGKFYEGGGKAFNPLKLADNYVNVNEETDLEDN"
     gene            55081..55560
                     /locus_tag="VB649_000602"
     CDS             55081..55560
                     /locus_tag="VB649_000602"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEP1669576.1"
                     /translation="MEHLAHYFTAHGGVFFAALGIVLAVALSGMGSAYGVGKGGQAAA
                     ALLKEEPEKFTSALILQLLPGSQGIYGFAIGILIWMKLTPELSVNQGLAYFLVSLPIA
                     IVGYFSAKHQGNVSVAGMQILAKRPKDFMKGVILAAMVETYAILAFVVSFILLNKIG"
     gene            55629..56213
                     /locus_tag="VB649_000603"
     CDS             55629..56213
                     /locus_tag="VB649_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HEP1669577.1"
                     /translation="MNDIIQLRQNVLEKAHQEGQQCLKIATDSLDTDFKERQQQGLHD
                     LKAKRQKELKALEQQFQVAQQQLKNQERQALLALKQDSIKELFEASLEKMTNFSKEEE
                     LAFLKQVLSKYPEQPLQVTFGEKTGQKFSSYDCAELRLAFPQLSYNQELIPQEAGFLV
                     SLDQVDDNYLYRYLLESVLKEESSRIIDMLFSEI"
     gene            56229..57227
                     /locus_tag="VB649_000604"
     CDS             56229..57227
                     /locus_tag="VB649_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEP1669578.1"
                     /translation="MPTFLELNTTISVKEKELLTKEQFDKLLQAPNTTTLARLLHQSV
                     YHLTVDDLNDLDRLESILMAELTKTYRWAFAETPQPDIVQLFTLRYTYHNVKVLLKAK
                     ASQADLSHLLLPIGDKPLVALEHLIRTMTSDEFPKEVVTEIQSIWAEYQDYQDIRVLE
                     IGTDLAYFKALKQIAQRLEDPVFQQAVLIVIDLYNLITVRRAKSQNKPISFMMQLLSD
                     EASRPSKTFITLEDDKDLMTWFENVTPDSYMTALKPYSEKLRQGTLQTTELEYLVDEC
                     LYHLFAKAKYQVDGPYVLARFLLAKSFEVKNLRLLAAALANDLPKERVIERMRPIA"
     gene            57224..57544
                     /locus_tag="VB649_000605"
     CDS             57224..57544
                     /locus_tag="VB649_000605"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEP1669579.1"
                     /translation="MTKTLYKVGVIGNRDVILPFQMIGFQTFPVIKPQDAINQLRQLA
                     MEDFGIIYITEDIAAAIPEALTHYDNQVLPAVIPLPTHQGTQGIGLSRIQAMVEKAVG
                     QNIL"
     gene            57745..59521
                     /locus_tag="VB649_000606"
                     /pseudo
     CDS             57745..59521
                     /locus_tag="VB649_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
     gene            59522..60937
                     /locus_tag="VB649_000607"
     CDS             59522..60937
                     /locus_tag="VB649_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEP1669580.1"
                     /translation="MSVLKEYRTVSEVVGPLMIVDQVAGVHYNELVDITLHNGERRKG
                     QVLEVQGDKAMVQLFEGSTGINLAKTKVRFTGHPLELAVSEDMVGRIFDGMGQPIDGG
                     PELIPEKYLDIDGQAINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDDNFAVVFAAMGITFEEAEFFMNDLRETGAIDRSVLFINLAND
                     PAIERIATPRIALTTAEYLAYEKGMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLIGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSQE
                     LYKNGFRPPINVLPSLSRLKDKGSGEGKTRQDHAATMNQLFAAYAQGKQAKELAVVLG
                     ESALSETDKLYVAFTNRFEEEYINQGFYTNRSIEESLDLGWELLSILPRTELKRIKDD
                     MLDRYLPKADTTMTKVFVAND"
     gene            60982..61608
                     /locus_tag="VB649_000608"
     CDS             60982..61608
                     /locus_tag="VB649_000608"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEP1669581.1"
                     /translation="MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDL
                     IRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVN
                     VPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMA
                     DDIEKTRRRVNGLEYSIIPQLEETIHYIELKLEEAERASLVRIMKITS"
BASE COUNT        18959 a        11029 c        13266 g        18426 t
ORIGIN      
        1 tggtaaggtc tatttaatgc gcaagatttg tggtatgatg aatatgattg agtattgatg
       61 ctttatggga ttaccggtaa ggttttgaaa aaggtttgtc actactaggt gcttttttag
      121 ctatagaaag acagttatgg attgatgtat tgtaactaat gttggaggtt aatggtggtt
      181 gagttttgag atatttacac tgataatcgg gtggaaactg gttgggtatc gggtaatgga
      241 gtgtggttct tcgtttaagc aaggagatta tcgtttggtg gttcatattt gcttgttaaa
      301 tgttagggat gagatgctga gtcagcaagg ccatgaagat aaagctgact ggccagagcc
      361 ttgagatgtg acgtttggtg gaagtccttt ttggtgagat ggcacagcat atagtaatat
      421 tagatcctga ggaagaattg ggactttcat taggcttgac tggggtatga cctcacttta
      481 caattcattt cgatgatggg tttgatgata cgtttttagt tcaggacttt gtagagttgg
      541 agaatttggt tctttatgag gaagaagtgc aggtaattcg ttgagacagt cgtgaagata
      601 ttttaggtat gattgatgaa ggttcgttca ttccttatct gaagtataaa ataaatttgt
      661 gctttgagat ggttggtcaa tataaagtcc atcaatctta gaagtaataa tttttgaatt
      721 ttttctgagg tttgtgtata tttgatagtg tactgatgta agaagtaagg agtactatga
      781 tggcaatcaa tgagagagct tctgcaaaaa tcaagttagg ccttgatact aagaataagc
      841 gatgagatgg ttaccacgat ttatcgatgg gcatgatgag tattgatctg tgtgactatg
      901 tgacggttga ccatatagat gacaataaga ttgtctttgc ctcaaactgt ccgaaaatac
      961 ctattaacta agataatgat gtttataaga tagttcagct aatgaaacat tgatttcaag
     1021 ttaaaagagg actttccgtt tacttggaaa agcggattcc catgtgtgct ggtatgggag
     1081 gaggttctag cgatgctgtt actatcagag cattaaatca gttatggctc cttactctta
     1141 gccgaaaaga tatgatggat attggtatac cgattggtag tgatgtgcct tattgcttgc
     1201 tttcaggttg tgcccaagtc actggtaaag gtgaagtggt ttgtcgcatt ttggggctgt
     1261 tatcgtcttg ggtggttttg gttaaaccag attgtggtat ctcgacttga acaacttttc
     1321 tagatattaa ttgtaaaacc atttcaagag tgtctactac tcatttggtt gcggcgattg
     1381 aagcgggtaa ctataatgat gggatattga ctgaaatgaa caatttgctg gaagatattt
     1441 tcattgccaa gcgacccttt attcaaaaaa taaaagagaa aacactgcaa gctggtgctg
     1501 ctactacttt gatgacagga agtggaccga ctgtttttgc tttgtgccag accgaaaaac
     1561 aaactataat agtttaaaag gactttgcaa ggaagttttt aaggtgagaa tgttgtaata
     1621 ttttgttggg attgcttctt tggaagcttc atgttataat taactggtta atgaaagagg
     1681 agatttatgg ggactttaga aaaaaaactt gataacttag taaatactat tttattaaaa
     1741 gcagaaaatc agcatgagtt attatttgga gcttgtcaaa gtgacgttaa gcttactaat
     1801 acgcaagaac atattttaat gttactatct cagcaacgtc tcactaatac agatttggct
     1861 aaggcattaa atattagtca ggcggcagta actaaggcta tcaagagttt ggtcaaacaa
     1921 gacatgctag caggaactaa ggatacggtt gatgctaggg tgacttattt tgaattaacc
     1981 gagttagcta agcctattgc gtcagaacat acccatcatc atgatgaaac cttaaatgtt
     2041 tacaaccgtt tattacaaaa attctccgcg aaagaattag agattgtaga taagtttgta
     2101 acagtttttg ctgaggaatt agaagggtaa tccatgagat acatatcagt gaaaaatctc
     2161 tcctttcaat atgaaagtga gccagtttta gaagggatca cttatcattt agatagtgga
     2221 gaatttgtca ccatgaccgg tgaaaatggc gctgcaaagt caaccttaat aaaagcaacc
     2281 ttaggaattt tacaaccaaa ggctggacga gttactattg ctaaaaaaaa taaagacggt
     2341 aaacaattaa ggattgctta cttaccgcag caagtagcta gctttaacgc tggttttcca
     2401 tccaccgttt acgagtttgt caaatcaggt cgctacccac gtagtggttg gtttagacat
     2461 ttgaacaaac acgatgaaga gcatgtacaa gcaagcttag aagcagtcgg catgtgggaa
     2521 aaccgtcata agagaattgg tagtttatca ggtggtcaaa aacaacgtgt ggttattgcc
     2581 cgtatgtttg cttctgaccc tgatattttt gtgctagacg agccaacaac gggaatggat
     2641 agcggtacta ctgatacctt ttatgaactg atgcaccaca gtgcacatca acatgggaaa
     2701 tccgttctga tgattaccca tgacccagaa gaagtgaagg cttatgctga tcggaacatt
     2761 catttagtca gaaaccaaaa acttccttgg cgttgtttca acattcatga agctgaaaca
     2821 gatgacgaaa aaggaggtca tggtcatgct tgatatttta tcctatgatt tcatgcaacg
     2881 ggcggtaatg gcggtagttg ccattagtat ttttgctccg attttaggta ttttccttat
     2941 tttacgtcgt caaagtttga tgagcgatac ccttagtcat gtttctttgg ctggggtagc
     3001 gcttggggta gtcattggta tttcaccaac catcactact attattgttg tggttttagc
     3061 tgctattttg ttagaatacc tgcgtgtagt ttacaaacac tacatggaga tttcaacggc
     3121 gattttgatg tcacttggct tggccctatc tctgattatt atgagtaagt cgcatagttc
     3181 atcaagcatg agtttagaac aatacctttt tggatcgatc atcacgatta gtatggaaca
     3241 agttgtcgcc ttgtttgcta ttgctgcgat tattttaatc ttgaccgttc tcttcattag
     3301 accgatgtac attctgacct ttgatgaaga tactgctttt gtagatggtc tgcccgttcg
     3361 cttgatgtct gttctattca atatcgtcac tggggttgct attgctttga ccattccagc
     3421 agcaggagca cttttggttt ctaccattat ggtcttgcca gcaagtatcg caatgagatt
     3481 gggtaaaaac tttaaaacag ttatcttact gggaattgtc atcggtttta gcggtatgtt
     3541 atctggtatt ttcttatctt atttctttga aacgccagct agtgccacta ttaccatgat
     3601 tttcattagt attttcctct tagttagtct aggtggaatg cttaaaaaac ggttatttat
     3661 aaatgcttta aaaagggggc aaggtcccaa ttttcttgat taatggtgat gccctcccaa
     3721 aagctatcat tagttaaacg aggaatcaaa tgaaggtgaa aatgagtccc ctcatccatc
     3781 aactccttgt cattgctgac gctagtgacg cctgaaatgg aaaggtgctg ctctagctta
     3841 gcaactagag cggcttgtaa gtcgatgaga tcatagcgca cttcctttgg tagttgtgtc
     3901 agactagtgt aatggtcttt ggaaatcagt aaaaggtgcc ccttttggat aggatcaata
     3961 tcaaaaacaa ccttgaaata ttgactttga gtcagtagct gatttgcttt gagctgatgg
     4021 caaaagatac attctgtcat aggtacatct ccttatgaaa aaacgagcca gagctcgttt
     4081 aatcggttat ctagtaagtg agaacagcgt attttttctt accgcggcga ataacggtta
     4141 attgatcatc aattttatca tcattactta attggtaatc taaatcttga acgcggtctc
     4201 cgttaatgta gattgctcca ttttgcacgt cttcacgcgc ttggcgtttt gatggggaaa
     4261 tatctgcggt gacaagcatg tcaacaaggt taaggctgtc ttctgattga acgtgataat
     4321 ttggtacatt gctcaatcct tgttttaatt cattagcaga aagatttttg atgtttccag
     4381 caaataactg ctcggtaatg ttaagagctt gtttataagc tttttcgcca tgaaccaagg
     4441 taaccacttc gcgtgccaag gttttttgag cgagacgctc gtgacgagcg gcattaaatt
     4501 gagtttcaat ttctgcaatc tcatctagag ataagaaggt gaagattttc aagaaacgca
     4561 ctgcatcatc atccatgaca tttaaccaga attggtacat ctcgtaagga gacgtcttat
     4621 cggcatcaag ccagacagca ttaccttctg atttaccgaa ttttttcccg gttgagtcag
     4681 tgatgagtgg tacagtcatg acgtgcccag ttttatcagc ctttttgcgg agcaattcag
     4741 taccagctgt catattaccc cactggtcag agccgccaat ttgtaaggtt acattatgct
     4801 tgtcattgag ttcgtagaag tcgtagccct gcatgatttg gtaagcaaac tcagtgtaag
     4861 aaatgcctgt ttcaatgcgt tttttaacag agtctttact catcatatag ttaacggtga
     4921 agtatttacc gacatcacgg aggaagtcaa taaagctgat ttgcgagaac cagtcgtagt
     4981 tgttgacaag ctctgcttta ttatcaccat tttcaaaatc aaggaaagta gacaactgcc
     5041 ctttaatctt gtcactccac tccaaaactg tttctttggt ttgaaggctg cgctctgcat
     5101 ctttaaagga aggatcacca attaaacctg tggcaccacc cacaagagcg taaggtttgt
     5161 gccctgctag ttgcaagcga cgagatgtta agatagccac tagatggccc agatgaaggc
     5221 tgtcagcggt tggatcataa ccggtataat aggatacttg cccttctgtt aatgctttga
     5281 caagggcttg ttcatcagtc gtttgaaaga ccaagccacg agctttgagt tcttcaaaaa
     5341 tattcatagg ctttctccat tttcattata gtttcgaatc attatatcaa aaaacgctac
     5401 tgctatgcaa gctttatcaa agtttggtat aatgataaat gaggtatttt atggtgaaat
     5461 ggaacacgaa acaaaagcgt ataagtcatc aaagattagg tctcttggat ttggggccgg
     5521 tgctattacg tacgttgaga ctactgtcta acttttttta tattgttatc ttcctttttg
     5581 gaatgatggg atttggtatg gcatttgggt atttggctag tcagattgaa tctgttaagg
     5641 taccaagtaa agaaagttta gttaaacaag ttgaatcatt aacgatgatt tcgcaaatga
     5701 actattctga taatagttta atttctactt tagatacgga tttacttcga acaccagtag
     5761 ctaatgatgc gatttcagag aatatcaaaa aagctattgt atcaacagaa gacgaacatt
     5821 ttcaagaaca taaaggtatc gtgccaaaag ctgtttttcg ggcaacattg gcttctgtat
     5881 tgggatttgg agaagctagt ggaggttcga ccttaacaca gcaattagtc aagcaacaag
     5941 ttttgggaga cgatcccaca tttaagcgca agtctaagga gatcgtttac gctcttgcct
     6001 tagagcgtta tatgtccaaa gacaatatct tatgtgatta tcttaatgtt tcaccttttg
     6061 gtcgtaacaa caagggccaa aatattgctg gtgttgaaga agctgcgcgt ggcatttttg
     6121 gcgtttctgc caaagattta acggtgccac aggcagcatt tttggcgggg cttccgcaga
     6181 gtcctattgt ttactctcct tatttgtcaa cgggacaact gaagtcagaa aaggacatgg
     6241 cttatggcat caagcgtcag caaaatgttc tctataacat gtaccgtaca ggtgttctgt
     6301 ctaaaaaaga atacgaggac tataaggctt atccgattca aaaggatttt attcaaccgg
     6361 gaagcgcaat agtaaataat cacgattacc tttattacac ggtgttagcg gatgctaaaa
     6421 aagccatgta tagctatttg attaagcgag ataaggtgtc tagtcgtgac ttgaaaaatg
     6481 acgagactaa ggctgcttat gaagagagag ccttaacaga attgcaacag ggtggctata
     6541 ccatcaccac aaccattaat aagcctattt acaatgcgat gcagacagcg gcagctcagt
     6601 ttggtggcct gttagatgat ggcactggta cagttcaaat gggaaatgtc ttgacagaca
     6661 atgcgactgg tgctgtgtta ggttttgttg gtggtagaga ttatgctctg aatcaaaata
     6721 atcatgcttt caatacagtt agatcgccag gttctagcat taaaccgata atcgcttatg
     6781 gtcctgctat tgatcaaggt ttaatgggga gtgctagcgt tttgtctaat tacccaacaa
     6841 cttactcgag tggccaaaaa atcatgcatg ctgatagtga aggaacagcc atgatgccac
     6901 ttcaagaggc cctaaatact tcttggaaca tcccagcttt ttggacacag aaattactgc
     6961 gtgaaaaagg ggtcgatgtc gaaaattata tgacaaaaat gggttataag attgcagact
     7021 actcgattga aagtttacct ctagggggcg gtattgaagt ctcggttgct caacaaacca
     7081 atgcttacca aatgctttca aacaatggct tatatcaaaa gcaatatatt gtagataaga
     7141 ttactgctag cgatggtaca gtcgtttaca aacatgaaaa taagccaatt cgtatttttt
     7201 ctgcagcaac agctacgatt ttacaagaat tgttgagagg tccgattact tcaggcgcta
     7261 cgactacttt caagaaccgt ttggcggcta ttaatccgtg gcttgctaat gctgattgga
     7321 ttggtaagac cggaacaact gagaattata cggatgtttg gctagtcctg tctactccaa
     7381 aagttaccat aggcggttgg gcaggacatg atgacaatac ctcattagcg ccattaacag
     7441 gatataacaa taattctaat taccttgcct atttagctaa tgccattaat caggccgatc
     7501 ccaatgttat tggagtaggg caacgtttca acttagatcc aggagtcatt aaggcgaatg
     7561 tcttgaagtc aacaggttta caaccaggaa ctgttaatgt caatggacat actttttctg
     7621 ttggtggaga aatgaccacc agtctatggt cccaaaaagg accgggggct atgacttacc
     7681 gatttgctat tggtggcacg gatgccgatt atcaaaaagc ttgggggaac ttcgggttca
     7741 gaaaaaatta ggttgccatt tatcgataaa aagggtataa tagcaataac tatttgtcgt
     7801 ccaatctagc tgaaatattg tccagttagg aagaacagca gttaaatcac actgataaag
     7861 tcagatttag ctgctctttt tgtgtctatt tttagaaaag atagggtttg taacctatat
     7921 ttaaatattc taaaaattaa catttagggc aaatgataac ttagttgcga tttgctgaaa
     7981 cagcaaagct taaatagaag aaggagctaa aaacttggca ggacatgaag ttcgatacgg
     8041 aaaacaccgt acacgtcgta gcttttcaag aatcaaagaa gttcttgatt taccaaattt
     8101 gattgaaatt caaactgact cattccaaga tttcctcgat tcaggtttga aagaagtatt
     8161 tgaagatgta cttcctattt caaactttac ggatactatg gaacttgaat ttgttggtta
     8221 cgaatttaaa gaacctaaat atacccttga agaagctcgt atccacgatg caagttattc
     8281 tgcaccaatc tttgttacct tccgtttggt caataaagaa actggtgaga ttaaaactca
     8341 agaagtcttc tttggtgatt tcccaatcat gacggaaatg ggtaccttta ttatcaatgg
     8401 tggtgaacgt atcatcgttt ctcagttggt gcgttctcca ggtgtttatt tcaacgataa
     8461 agttgataaa aacggtaaag ttggttacgg atcaacagtg attcctaacc gtggggcttg
     8521 gttggaatta gagactgact caaaagacat tgcctacact cgtattgacc gtacccgtaa
     8581 gattccattc acaaccttgg ttcgtgccct tggtttctca ggtgatgatg aaattgttga
     8641 tatctttggt gaaagcgacc ttgttcgtaa taccattgaa aaagacattc acaaaaatcc
     8701 aagtgattct cgtacagacg aagcccttaa agaaatttac gagcgtcttc gtccaggtga
     8761 gccaaaaact gcagatagct ctcgtagtct cttgattgcg cgtttctttg atgcacgtcg
     8821 ttacgatttg gctgcggttg gtcgttacaa agtgaacaaa aaacttaata tcaagactcg
     8881 tcttttgaac caaatcattg ctgaaaacct tgtggatgct gaaactggcg aaattttggt
     8941 agaagctgga actgagatga ctcgtagcgt catcgaatcc atcgaagaac accttgacgg
     9001 tgatttgaac aagtttgttt acacaccaaa tgattacgct gtggttactg aacctgttgt
     9061 tcttcaaaag ttcaaggttg tgtcaccaat tgatcctgat cgtgtagtaa ctattgttgg
     9121 taatgccaat ccagatgata aggttcgtgc attgacacct gctgacattt tggcagaaat
     9181 gtcttacttc ttgaaccttg cagaaggtct tggaaaagtt gacgatattg accacttagg
     9241 taaccgtcgt atccgtgccg ttggtgaatt gcttgccaac caattccgca tcggtcttgc
     9301 tcgtatggag cgtaacgtgc gtgagcgtat gtctgttcaa gacaacgatg tgttaacacc
     9361 acaacaaatc atcaatatcc gtcctgtcac agcagctgtc aaagaattct tcggttcgtc
     9421 tcagttgtca cagttcatgg accaacacaa cccattgtca gagttgtctc acaaacgtcg
     9481 tttatctgcc ttaggacctg gtggtttgac acgtgaccgt gctggttatg aggttcgtga
     9541 cgtgcattac acgcactatg gccgtatgtg tccgattgaa acacctgaag gaccaaacat
     9601 tggattgatt aacaacttgt cttcatttgg acatcttaat aaatatggtt tcatccaaac
     9661 accttaccgt aaggttgacc gtgcgactgg tacggtaact aacgagattg tttggttgac
     9721 tgccgacgaa gaagacgaat acacagttgc acaggccaat tcgaaactaa acgaagatgg
     9781 cacttttgct gaagaaatcg ttatgggtcg tcaccaaggt aataaccaag aattttctgc
     9841 aagtgttgtt gatttcgttg acgtttcccc taaacaggta gttgctgttg cgacagcatg
     9901 tattcctttc ttggaaaatg atgactccaa ccgtgccctc atgggtgcca acatgcaacg
     9961 tcaggctgtg ccattgattg atccaaaagc accatatgtt ggtactggta tggaatatca
    10021 agctgcccat gactcaggcg ctgcggtgat tgctcagcac aatggtaaag ttgtcttttc
    10081 tgatgctgaa aaagtggaaa tccgtcgtca agatggctca cttgatgttt accacattac
    10141 caaattccgt cgttcaaact caggaacagc ctataaccaa cgcacccttg ttaaagtagg
    10201 agacatcgtt gaaaaaggtg atttcatcgc tgatgggcct tctatggaaa atggtgaaat
    10261 ggctcttgga caaaacccag tcgttgctta catgacttgg gaaggttata acttcgagga
    10321 cgctgttatc atgagtgagc gccttgtgaa agaggatgtt tacacatctg ttcacttgga
    10381 agaattcgaa tctgaaacgc gtgatacaaa acttggccct gaagaaatca ctcgggaaat
    10441 cccaaatgtt ggtgaagaag ccctcaaaga ccttgacgaa atgggcatta tccgtatcgg
    10501 tgctgaggtt aaagaaggcg acatcttagt aggtaaagtc acacctaaag gtgaaaaaga
    10561 cctttctgct gaagaacgtt tacttcacgc catctttggg gataaatcgc gtgaagtgcg
    10621 tgatacctca cttcgtgtcc ctcacggtgg tgatggtatc gttcgtgatg tgaaaatctt
    10681 tacacgcgct aacggcgatg aattgcaatc aggtgttaat atgcttgtgc gtgtttacat
    10741 cgctcaaaaa cgtaaaatca aggtcggaga taaaatggcc ggtcgtcacg gaaacaaggg
    10801 tgtcgtttca cgtattgtac cagttgaaga catgccatac cttccagacg gaacaccagt
    10861 tgacatcatg ttgaaccctc tcggggtgcc atcacggatg aatattggtc aggttatgga
    10921 acttcacctt ggtatggctg ctcgtaatct tggcattcac attgcaacac ctgtctttga
    10981 cggggcttca tcagaagacc tttgggacac tgttcgtgaa gctggcatgg atagcgatgc
    11041 taagacggtc ctttatgatg gtcgcaccgg tgaaccattt gacaaccgtg tatccgttgg
    11101 tgtcatgtat atgatcaaac ttcaccacat ggttgatgat aaacttcatg cccgttctgt
    11161 aggaccatac tcacttgtta cccaacagcc acttggtggt aaagctcaat ttggtggaca
    11221 acgttttggt gagatggagg tttgggccct tgaagcttat ggtgcatcaa atgttcttca
    11281 agaaatcttg acctacaagt cagatgacgt cacaggacgt ttgaaagcct atgaagcgat
    11341 tactaaaggt aaaccaattc caaaaccagg tgtaccagaa tccttccgtg ttcttgtaaa
    11401 agaattgcaa tcgcttggtc ttgatatgcg tgtgcttgac gaggatgata atgaagtgga
    11461 acttcgtgat cttgatgaag gtgaagacga tgatattatg catgttgacg atctcgagaa
    11521 ggcacgtgaa aaacaagctc aagaaaccca agaagtttct gaaacaactg acgaaaaata
    11581 agcaatcaat tcttattaaa taattagtta ctggtctggg gcaaaggccc caggaactgg
    11641 taaagtcatc aaaggcagaa aggtaaaact agtggttgac gtaaatcgtt ttaaaagtat
    11701 gcaaatcaca ttagcctcac caagtaaggt ccgttcatgg tcttatggtg aagttaaaaa
    11761 acctgaaaca atcaactacc gtacattaaa accagaacgt gaaggactct ttgacgaagt
    11821 catctttggt ccaacaaaag actgggaatg tgcgtgtggt aagtacaaac gtatccgtta
    11881 taaagggatc gtttgtgacc gctgtggggt tgaggtaact cgtgctaaag tacgtcgtga
    11941 acgtatgggt cacattgagt taaaagctcc tgtatcacat atctggtatt tcaaagggat
    12001 tccatctcgt atgggattga ctcttgatat gagtcctcgt gcccttgaag aagtgatcta
    12061 ttttgcggct tatgtggtca ttgatccaaa agatacaccg cttgaaccaa aatcattatt
    12121 aacagaacgt gaataccgtg aaaaactaca agagtatggt catgggtcat ttgtcgctaa
    12181 gatgggtgct gaagccattc aagatctctt gaaacgtgtg gacttggcag ctgaaatcgc
    12241 tgaattaaaa gaagagttga aatctgcttc tggtcaaaaa cggattaaag cagttcgtcg
    12301 tttagacgtc cttgatgcct ttaacaaatc tggaaataaa ccagaatgga tggttcttaa
    12361 catcctgccg gttattccac cagatcttcg tccgatggtt caattggatg gtggtcgttt
    12421 tgcggcatca gacttgaatg acttgtaccg tcgtgtgatt aaccgtaata accgtttggc
    12481 acgtttgtta gaacttaatg cccctggcat cattgttcaa aatgaaaaac gaatgcttca
    12541 agaagccgtt gatgctttga ttgataatgg tcgtcgtggt cgtccaatca ctggaccagg
    12601 aagtcgtcca ttgaaatcat tgagccacat gcttaaaggt aaacaagggc gtttccgtca
    12661 aaacttgctt ggtaaacgtg tagacttctc tggacgttcc gttatcgctg ttggtccaac
    12721 ccttaaaatg tatcaatgtg gtgtcccacg tgaaatggct atcgagcttt ttaaaccatt
    12781 tgtaatgcgc gaaattgttg ccaaagaata tgctggtaac gttaaagccg ctaaacgtat
    12841 ggttgaacgt ggcgacgaac gcatctggga tatcttagaa gaagttatca aagaacaccc
    12901 agtcctactt aaccgcgcac cgactcttca cagacttggt attcaagctt ttgaaccggt
    12961 tcttattgac ggtaaggcac ttcgtcttca cccacttgtg tgtgaggcct acaatgccga
    13021 cttcgatgga gaccaaatgg ccatccacgt gccactttca gaagaagcac aagctgaagc
    13081 tcgtcttttg atgcttgctg cagagcacat cttgaaccct aaagatggta aaccagttgt
    13141 taccccatct caggatatgg ttcttggtaa ctactatctt acgatggaag atgctggtcg
    13201 cgaaggcgaa ggtatgattt tcaaggataa agacgaagct gtgatggcat atcgtaatgg
    13261 ttatgctcat cttcatagtc gtgtgggtat cgctgttgac agcatgccaa acaaaccttg
    13321 gaaagataat caaagacata aaatcatggt gacaactgtt ggtaagattc tctttaacga
    13381 tatcatgcca gaggaccttc cttacctcca agagccaaac aatgccaact tgacagaagg
    13441 aacacctgat aaatacttcc ttgaacctgg tcaagacatc caagaagtga ttgatggctt
    13501 agaaatcaat gtgccattta agaagaaaaa cctcggtaac atcattgcgg aaaccttcaa
    13561 acgtttccgt acaacagaaa cgtcagcctt ccttgaccgc ttgaaagacc ttggttacta
    13621 ccattcaacc cttgctggtt tgacagtggg tatcgctgac attcctgtta ttgataataa
    13681 agctgaaatc attgatgctg ctcaccatcg tgttgaagaa attaacaaag ccttccgtcg
    13741 tggtttgatg acagatgatg accgttatgt tgccgttaca acaacatggc gtgaagctaa
    13801 agaagccctt gaaaaacgtc tgattgaaac acaagatcct aagaacccaa tcgttatgat
    13861 gatggactca ggagctcgtg gtaacatctc aaacttctca cagcttgctg gtatgcgtgg
    13921 tttgatggct gctcctaacg gacgcatcat ggaacttcct atcttgtcaa acttccgtga
    13981 aggtttgagc gttttggaaa tgttcttctc aacccacggt gcacgtaaag ggatgaccga
    14041 tacggccctt aaaacagccg actcaggtta ccttactcgt cgtttggttg acgttgccca
    14101 agatgttatc attcgtgagg acgattgtgg cactgatcgt ggtcttctta tccgtgctat
    14161 tacagatggt aaagaagtta ccgaaacgct tgaagagcgt cttcaaggtc gttacacacg
    14221 taaatcagtc aaacaccctg aaactggtga agtcttgatt ggtgctgacc aattaatcac
    14281 tgaagacatg gctcgtaaga ttgttgatgc aggtgttgaa gaagtgacca ttcgttctgt
    14341 ctttacctgt gcgactcgtc atggtgtctg ccgtcactgt tatggtatta acttggcaac
    14401 tggtgatgct gttgaagtgg gtgaagcagt tggtactatt gctgcccaat ctatcggtga
    14461 gcctggtact cagcttacca tgcgtacctt ccacacgggt ggtgtagcct caaataccga
    14521 tatcacccag ggtcttcctc gtattcaaga gatctttgaa gcacgtaatc ctaaagggga
    14581 agcggtcatt actgaagtga aagggaatgt cgtcgagatt gaagaagatg cgtcaactcg
    14641 taccaagaaa gtctacgttc aaggaaaaac tggcatgggc gaatatgtcg taccatttac
    14701 agcacgtatg aaagttgaag ttggcgacga agttaatcgc ggagctgccc ttacagaagg
    14761 gtcaattcaa ccgaaacgtc tccttgaagt gcgtgatacc ttgtcagttg aaacgtacct
    14821 tcttgcagaa gtacaaaaag tttaccgtag ccaaggggta gaaatcggag acaaacacgt
    14881 tgaggtaatg gttcgccaaa tgcttcgtaa agttcgtgtc atggatccag gtgatacaga
    14941 cctccttcca ggtacactta tggatatttc tgatttcaca gatgctaaca aagatattgt
    15001 tatctctggt ggtattcctg cgacatctcg tcctgttctt atgggtatta ctaaggcttc
    15061 ccttgaaacc aattccttct tatcagctgc atccttccaa gaaacaactc gtgttcttac
    15121 agatgctgct atccgtggta agaaagacca cttacttggt cttaaagaaa atgttatcat
    15181 tggtaaaatc attccagctg gtactggtat ggcgcgctac cgtaacattg aaccacaagc
    15241 gatgaatgag attgaagtga ttgatcatac agaagtctca gcagaagcag aataatctca
    15301 tgaaagagtc cttaggggct cttttttgtc tgagtttgtt ggcagtaaaa agcattgaca
    15361 atcagtctta gtcccaatga gcagatgttt ttcaaaatac ttatgattta gctataataa
    15421 tgcataagag gaataggtaa tgtgttatgt atcaagtaat taaaatgtat ggtgattggg
    15481 agccttggtg gttcatcgat ggatggcaag acgatattat agatgagcaa caatttagtg
    15541 actggcaaga agcgcttgat tattttaatc aagaatggca gcgcatgaaa gctatttttc
    15601 ctagttatca tagtcaaaag aatttgttag ctactttttg ggaaaaagaa gataaaagat
    15661 ggtgcgagga ctgtgacgaa gatttacagc agtttcattc tcttttactc cttaaaaata
    15721 aagatattgt accaagcaat aattatatcc ctgaatttga acaacgaaat gattcaccac
    15781 aggtagctta tctttgcaag ttaaaccttt aagtgtttgt taaaaacaaa aaaagaaaat
    15841 atcacttctt ctgatatttt ctttttttgt ttacgaataa atgagtaagg aggaattatg
    15901 gtacaagcat tagcaaaagc tattctagca aaagctgaac aggttcaggc acaagatatt
    15961 tatattttgc caagagcaga tcaatatgat ctttttttac gaataggaga tgaaaggaga
    16021 ttagttgatg tttatcagag cgatcggatg gctcctctta ttagtcactt taaattcgtt
    16081 tcaggaatga tagttggtga aaagagacgt tgtcaggtgg gttcatgtga ttataagctt
    16141 agtaaagata agcagttatc tttgcgctta tctagcgtgg gtgattatcg cgggcaagaa
    16201 agcttagtga ttcgtctgct tcatcatcaa aataaaagtg tacattattg gtttgatgga
    16261 ttgacaaaag tagccaatca ggttggcggt agagagttgt atttatttgc aggaccagtt
    16321 gggtctggga agacaacctt gatgtaccag ctgatttcga gttatcatca agaagcacag
    16381 gttattagta tagaagatcc tgtagaaatt aaaaatcacc agattttaca attacaagtg
    16441 aatgatgata ttggtatgac ttatgacaat ttgatcaaac tgtctttacg ccatcgacca
    16501 gatattttag ttattggtga gattcgagat agtcaaacag caagagccgt tattagggct
    16561 agtctaacag gtgccatggt tttttcaacg gttcacgcta aaagtatctc gggtgtttat
    16621 gtaagattgt tagaacttgg tgtaacgaaa gcagaactgt ctaattgctt agcattaatt
    16681 gcttaccaaa ggttacttaa tggaggagca ttgattgact ctactcaaaa cgaatttgaa
    16741 tattattcct catcgaactg gaatcaacaa attgatcagc ttcttgaggc aggacatctc
    16801 aatcccaagc aagctaagct tgaaaaaatt atctagtaaa catcagcata aattcattca
    16861 attactagct aatcttttat ctacaggatt tagcttcgca gaggttattg cttttttaaa
    16921 aagaagccag ttgcttcagc tagattatgt tcttaaaatg gaagagtctt tattaaaagg
    16981 acaaggctta gcagatatgt tgtcgggttt aggtttttca gatgctattc ttactcaaat
    17041 tagtttagct gatagacacg gtaatattga aacaacatta gtagcgattc aacattactt
    17101 gaaccaaatg gcaaggatca gacgaaaaac tgttgaagtt atcacctatc ctcttattct
    17161 tttacttttt ctttttgtga tgatgctagg gttgagacgc tatttagtcc ctcaattaga
    17221 aactcaaaat cagataactt actttcttaa ccattttcct gccttcttta taggtttttg
    17281 ctcaggtctt attttgttgt tcgggatggt atggctacga tggcgatctc aaagccgctt
    17341 gaaactctat agtcggctaa gccgttatcc ttttttaggt aaactgttaa aacaatactt
    17401 aactagttat tatgctagag aatggggtac gttaataggt caaggtcttg atttgatgac
    17461 tattttagac attatggcca ttgagaaatc ctcactaatg aaagaattag ctgaggacat
    17521 cagaatgagt ctgcttgaag ggcaagcctt tcacattaaa gtagctacct accctttttt
    17581 taaaaaagaa ttaagtttaa tgattgaata cggtgaaatc aaatcgaaac tgggggctga
    17641 gttggaaatc tatgcccagg aaagctggga acaatttttt agtcagcttt atcaagtgac
    17701 acaacttatt caaccagcta tttttttagt agttgctgtg acaatcgtca tgatttatgc
    17761 ggcaatccta ttaccaattt accaaaatat gggaggtatt ttttaagatg attaatcaat
    17821 ggaacaactt acgacacaag aagctaaaag gatttactct tctagaaatg ttattggtga
    17881 ttcttgtcat cagtgttttg atgctattat ttgtgcctaa tttaagcaag caaaaagaca
    17941 gggttacaga aacaggtaat gccgctgttg ttaaattagt ggagaatcaa gcagaactat
    18001 atgaattatc tcaaggctca aaaccaagtt tgggccagtt aaaggcagat ggtagtatca
    18061 ctgagaaaca agaaaaagct tatcaagact attatgacaa acataaaaat gaaaaagccc
    18121 gtcttagcaa ttaaagcttt tactttgctt gaaactttac taagtttgtc agtgatgagt
    18181 ttcattatat tgggattgtc tgtaccagtg acaaaaagct atcaaaaagt agaagagcat
    18241 ctgtttttta gccattttga acatttgtat cgacatcagc aaaagttagc catattacag
    18301 caaaaacagc gcgtcttgga tatttcttca acaaaaattg ttacagaagg taatagccta
    18361 acagttccta aatcaataac agtgaatcat ccttatcggt tagttattga tcagatggga
    18421 ggcaaccatt ccttagctaa aattattttt gacatgactg atcgatgctt taaataccaa
    18481 ttttatctag ggagtgggaa ttatcaaaaa acaagtcaaa gcttacatag cccttgaaag
    18541 tatgatcgca acaggcatcc tctttagtat tgtcattctc gtcttaagca gtttacagca
    18601 gagtcaggct gctctaacgt actatcgaaa gcagcaagaa aagcttaatc tagccttgat
    18661 ggcagtacaa actagaacta aagagatgac attaaatggt tgtcatatta ctattttacg
    18721 tacggataga tacattagta ttcacgatga tgaaggagaa gtgatgaaga ttgagtaaac
    18781 aattaagtaa cataaaagct tttacccttc tagaggcgtt aatagcctta ctcgtgatat
    18841 cagggtcttt attggtttat caaggtttga cccaaaccct ccttaaacgt agccattatc
    18901 tagcccgtca tgatcaagac aattggctct tattttctca tcaattgcga gaggagttaa
    18961 gtggagcaag attttacaaa gtagctgata ataaactata cgttgaaaag ggaaagaaag
    19021 tactagcttt tggccaattt aaaagtcatg attttcgaaa atcagctagt aatggaaaag
    19081 ggtatcaacc catgttattt ggaatatcac gtagtcatat tcacatagag cagtcacaga
    19141 tttgcattac tttaaagtgg aaaagtgggt tagaaaggac tttttattat gcctttcaag
    19201 actaatctca aagcaggcat ccttttgtat gctatgttta tggctagtat ttttttgctg
    19261 gttttacagg tttacctttc tcaagtgaca gctctacaca aggaatacca agctcaaact
    19321 gactatgtta aagcccgact gatagcagaa atagtttatc aagatcatag atataaagct
    19381 tctaatcctg tcttttttaa aggtggtcaa gtcatttgtc gagagcgaaa agagagatgg
    19441 atgttaattg ttaagttaga tcagcaacga cagtatcagt ttgaatacct taaacccaaa
    19501 caatatagtc aataaatagt attgttgtca taaatcctta aaatgatcca atatatagta
    19561 attaaaggtg acacttcttt tcatttcaag tgtaatttgg tatgataagg ttatgacttt
    19621 tgaaaaaatt gaagaagctt atcagctgct cttagagaac tgtcaactaa ttgaaaatga
    19681 tctaaaaaca catatatacg atgccattgt tgaacaaaac tccttttatt taggggctga
    19741 gggagctagt cctcaagttg ctcaaaatag tgataaactg aaagccttgt gcctgacaaa
    19801 agaagaatgg cgtaaggcct accagtttct ttttattaag gcagctcaga ctgagcaact
    19861 ccaagccaac catcagttca caccagatgc tattggcttc attctgctgt atcttttgga
    19921 acaattgagt gataaagata gcttagaggt acttgagatt ggaagtggaa cagggaacct
    19981 agcccaaacc cttctcaaca acacgagcaa gagccttgat tatgtaggga ttgaacttga
    20041 tgatctcttg attgatctgt cagccagtat tgctgagata atggattctt cagctcattt
    20101 tattcaagaa gatgcggtaa ggcctcaatt actaaaagaa agtgacattg tcatcagtga
    20161 cttaccagtt ggttattatc ctaacgatga tattgccaaa cggtacaagg tggctagttc
    20221 agataagcat acctatgccc atcacttatt aatggaacag tctttaaaat acttgaaaaa
    20281 agacggtttt gcgatttttc tggcaccagt caatttattg acgagccctc agagccagtt
    20341 attgaaacag tggttaaaag attatgctca ggtggtgacc ttgattacgc taccagattc
    20401 tatttttggt catccctcaa atgccaagtc cattattgtc ttacaaaaac aaacagacca
    20461 cccaatggaa acctttgtct atccaattcg ggatttgaag cgtgcagaga atattcatga
    20521 ttttatggaa aatttcaaaa aatggaaact gagtaatgtc aattaattga ttttttgtta
    20581 taataaaaaa gcatcacaga aaacgatttc aagagaggtt aaaaatgtca aagacaattg
    20641 caattaatgc aggtagttct agtttaaaat ggcaacttta tcagatgcca gaagaagaag
    20701 tgttagcaca aggaattatt gagcgtatcg gtctcaagga ttctatttca acagttaagt
    20761 acgatggcaa aaaagaagag caaattcttg atattcacga tcatacagaa gctgttaaaa
    20821 tcttattgaa cgatttgatt cactttggaa tcattgcagc ttatgatgaa attacaggag
    20881 ttggacaccg tgttgttgct ggtggtgaac ttttcaaaga atccgttgtg gttaatgata
    20941 aagttcttga gcagattgaa gaattatccg ttttagctcc acttcacaat cctggagcgg
    21001 cggcagggat tcgtgccttc cgtgatattt tgccagatat taccagtgtt tgtgtgtttg
    21061 acacgtcatt tcacaccagc atggcaaagc atacttacct ttacccaatt cctcaaaaat
    21121 attatacgga ctacaaggtt cgtaaatatg gagctcatgg gacaagtcat aaatatgtgg
    21181 cgcaagaagc tgctaaaatg cttggtcgtc cattagaaga attaaaacta attactgctc
    21241 atattggaaa tggtgtctca attacagcta attaccacgg taaatcagtt gatacctcaa
    21301 tgggattcac tccattagct ggtcctatga tgggaacacg ttctggtgac attgacccag
    21361 ctatcattcc ttatttaatt gagcaagacc cagagttaaa agacgctgct gatgttgtga
    21421 atatgttaaa taagaaatca ggtcttagtg gggtgtcagg catttctagt gatatgcgtg
    21481 atatcgaggc tggtttacaa gaagataatc cagatgctgt tttagcttac aatatcttta
    21541 ttgatcgcat taaaaaatgc atcggtcaat attttgctgt tttgaatgga gcagatgctt
    21601 tggtctttac agctggtatg ggtgaaaatg caccattgat gcgtcaagac gttattggtg
    21661 gcttaacatg gttcggcatg gacattgatc ctgagaaaaa tgtttttgga taccgtggtg
    21721 acatttcaac tcctgagtca aaagtgaagg tgcttgttat ctcaacagac gaagaattgt
    21781 gcatcgcgcg tgacgttgag cgtttgaaaa atacaaaata aaagagacta agtctcaata
    21841 gattaaccaa gtaaggcaac actttacttg gttttttatg aggtttatct gttagttatg
    21901 gtgcctaggt attagttctg atcagtctcc ttgctttttg taatcttgtg ctaggcgatt
    21961 tggatgtcag ccttatttag agtttttaat tgcttcaacg cttttcttgt atgtgtttat
    22021 agagcccaat aatctaaaag actatttgat aacagtttat gatgagcgta atcgtgcgat
    22081 tcgaaaacag acgcaagttt actgctttta cctgatgatt gttctatttg ttgccttatt
    22141 ctttttcttc ccttgcttaa tccttcgaga ccttgtttct tataagctac ctttgatttt
    22201 tgcttacctt tacttgatta tcagaagtct ggtggctaag aaaatgtagg cactagggaa
    22261 aataacaact aatagtcaaa aacctccgtt tgatacgagt caggttcttt gttagatgac
    22321 ttgtctaacg gttgagtttc ctgtctggtc aacggaggtg tttgtattgt tgtctgattt
    22381 gtattggggc acttatttta caagctttta gccttatcga tggttttgtc aatggcagag
    22441 ctgacagtag ttgtgaggcc aaggcgttct aactccatca gaccagcaat agttgtgcca
    22501 ccggggctac aaatagcgtc aatgaaatcg tgcggacttt gagaactggt cttgagattg
    22561 ctggcgctag ccaagactgt ttgagtaaca atctccagcg cctttgcttt aggcatgcca
    22621 ttcttgacgc cagccttagc caaagcctca ataaagagat aaatataggc aggacttgac
    22681 cctgctaaag cggtaaaggt gtcaaaattc ttttcactaa tatcaaatgt gctaccaaag
    22741 ctatctgtta agtttcgaac acgtgcttgt aattcctggg acaccaaagc atttcccgtt
    22801 aaagcggtac tgctttggag aatttgtgca ttcatatttg gcatgatacg tagcagcgga
    22861 aggtcttgtc ctacgaatgt tgctagtcgt tgaagggaaa tgcctgctgc catagatata
    22921 ataggctgtt tgaagtgaag cggtttgagt accgtttcaa atagttgagg cttgatgcct
    22981 aaaataacaa gatcaacctg gtcaataagg tcttggtggg acatagcata aggcagtgtt
    23041 aactgctccg caatttcctt ggaccgttct aaagatgatc ctgaaatgat aagttcatgg
    23101 ggtgtttgtt taaggccttt gatgatagcg ctagccattt tgccaacacc aataatgcca
    23161 attttcattc tgttgctcct tgtgggatat tacggttaat caggctaacg ctagtttagt
    23221 aacgtttaat caagtcaacg gttgagcgat ccagtttttt gataatggct tgtaagaagg
    23281 cttgggcttc tacgaaatca tccatagcgt agagggtttg atgagagtga atgtagcgtg
    23341 cacagactcc gatggttgtt gatgggacac caccattttg aaggtgtgca gcacctgcat
    23401 ctgtgcctcc cttgccacaa tagtattgga aattgacacc agcgtcctca gcagtagtca
    23461 gtaagaagtc gcgcatatct ttgagcatga catggcctgg gtcgtaaaag cgcaataagg
    23521 taccatctcc gattgttcca ggattgccat aaatatcacc agcaggcgaa caatctactg
    23581 cgaaaaagag ttcagggtcg aacttggtgg ttgagacgtg ggctccgcgc agaccaactt
    23641 cttcttgaac gttagcacct gcaattaggg tgttgttaag gtcttgtcct tttaacgctt
    23701 caagcatttc tgttatcatg agaacgccat agcgattgtc ccaagctttt gaaataatat
    23761 ttttttgatt ggctgttagg atcgtttcag attgagggac aataatatca cccggtgtaa
    23821 tgccaaagct ttcagcttct gccttatccg taaagccacc atcaaacaca atattttcga
    23881 tatttggtag actagcagag ccatttgccc cacgtaaaaa atggggaggt accgatcctg
    23941 aaataagggg aataacttgg ccagtgcgtg tgtaaagggt aaaccgttgt gaactgacaa
    24001 caagtgggtt ccaaccaccg ataccaacca cgcgtagcgt tccgtcaact ttgatatcac
    24061 tgaccataaa accgacttcg tccatgtgcg cagctactaa aatacggggg gctttttcag
    24121 ctttactatc tctgatacca aaaatgccac caagcccgtc tgtttcaaca cggtcaacca
    24181 gcggggttat tttggtgcgt aggtagtcac gaacgctatg ttcatagccc gcaatgccat
    24241 ccagttcggt aacttctttg atttttgaga ataagtctgt catttttcat ctccatttac
    24301 aaggtttcag accagttcaa cgcggtcatc tccctatatt ctaccacttt ttaagtaaga
    24361 atgggtttca cagcaaagaa aaatcccaga gactagagat ctctggaaga agtgtttgtc
    24421 ttttggcgat aacctgtttt tttaggcagc aaggaaatca ttaaaatgat aaagcacaag
    24481 ctggttaata agaatagtag ggcgcttagg atgcgaaaag actcttcact agcgaaaagt
    24541 aaggataatg gagtcataag gagaaccttc cattttaggt taatcagtga tttttatagc
    24601 gtggttaaat taataataaa ccacacctaa tcaacgtacc tttagtttag ttgtttttac
    24661 tatttttgtc aatacataac agtagaaatc tttagttttc ttatttcaga tcgtccaatt
    24721 tgatcttttt atgataaaat gagggatatg agtaaaaaga aaataggtat gatttcaggt
    24781 atctttggat ttagtttagc tattggccta ggaatagtta tcaaagatta ttgccaagac
    24841 aggaagcgcc gacaaatgac aagggattta cgcacctttt tttcaccttt aggacaaatc
    24901 gaagttttat atatcaatcc ttgtcaggtc aaacaagatt atatttcagg tggggttgtt
    24961 atgtcaaacg gcaaacagta ccaattcacc tatcacagtc gacaaattag ttttgaggag
    25021 gacaagtgat gatcagaccg acttcttatg agtcattagc ggctcttgtt gaaaaagaag
    25081 ataagctggt gttatttttt acggcagact ggtgtccaga ctgtcaattt atttatccta
    25141 ttatgccaga aattgaagca gaacttacag atatgacttt tgtttgtgtt aatcgtgatc
    25201 agtttataga ggtagcacaa aagtgggata tttttggtat tcctagtttt gtcgtgattg
    25261 aaaaaggtca ggaagtaggg cgtctggtta acaaaatgag aaagacaaaa actgagatta
    25321 tgcatttttt agctgcttat caataagaaa agaggaagaa taaatgattt ttgcatacaa
    25381 taaagaacaa gttggcgatg tcttgatggt tatcttacaa gacaccaaag atatcaaacg
    25441 tcaagtagaa cgaaaaggca aagtagcccg tgtttttgca gaagaaagcg gcaaaaccct
    25501 tgcttggaat atctttgaag cgtcaagctt gattactatt gaaggcaatg gacagatttt
    25561 tttgacagac gaggaccttg caagattaaa tgcagagctt gctaaggaag gattttcaga
    25621 aaggcttgaa ccgactgtgg gacctgtttt tgtggttggt caaattgttg agatggtggc
    25681 tcatccagat agcgaccatc ttaatatctg tcaagtggct attggtgaag atcaaacggt
    25741 tcaaatcgta gcgggcgcac caaatgctgc gcttggttta aaaacgattg ttgccttacc
    25801 aggtgctata atgccaaatg gtagtctgat tttcccagga aaattgcgtg gtgaagaaag
    25861 ttatggtatg atgtgctctc ctcgtgagtt agccttgcca aatgcaccgc aaaaacgtgg
    25921 cattattgaa cttgatgagt cagctgtggt aggagaagct tttgacccag ccaaacattg
    25981 gaaaggttag aaaaaccagc tgaaatagga ctgtatttaa ctaaatgacc agaaaaaagg
    26041 attaggagcc cctagtcctt ttttcttatg ttttcaaaaa cgtttaaaat gaaacttatt
    26101 ttaccacaat ttttacgaat aataaggtaa ggaggtcagt atgtataata aagtgatagc
    26161 aatcggtcgt ttggtagcta aaccagaatt ggtaaaaaca gctacggata agcatgtagc
    26221 acgtctctct ttagctgtta atcgaagatt taaaaatgct tctggagagc gagaagcgga
    26281 ttttatctct gttgttgttt ggggaaagtt agctgaaacc ttggtttctt atgctagcaa
    26341 aggtagtttg atgtctattg atggcgaact taggactcgc aagtataata aagatgggca
    26401 agtgcattat gtgacagaag ttctctgcca atcatttcaa ctgcttgaaa gtcgtgctca
    26461 gcgcgctatg agagaaaata atgttactaa tgatctagtt gatttagtct tagaagaaga
    26521 tactcttccc ttttgatagg ggataatgcc tctcatcagg gttcagctga ttactgaaat
    26581 atatgatgag gtgatacccg agcaacaaaa gtgtgaccag atacttctga taaaaataaa
    26641 aaaacacctt acgagtatga acgaagtttc aagtgctaga tgttggaact ttgttcatca
    26701 taggaatagt agggtgtttt ttagtgtatt acttcttttt gttgctagtg ttaaggttta
    26761 cttgcttaca aacggttatc aggccactag aattcttata ataaatggag ctctttgagt
    26821 ttggtgtcaa tcatttttaa gacagtcgcc aaatcttgtg gtttttgaac gaagtcaagg
    26881 gaattgccat caattttcat ttttggagag accttgtagt cttcgtacca ggttgggtat
    26941 tcaccgtgga cttgatggta atattgctca agactaggat tgccgtcgac ctgctcaaaa
    27001 cttcggccac gtttttcaat gcgctcaagc attttgtcaa aagacacatc aatgtagatg
    27061 agaagatcag ggcgtttttt aggcatgcct tctagttctt ctaacatgtt ggcgagaagt
    27121 tcctgataga tgtcaagttc tgtcttagtg acattgccat ttttgtagtt aagttttaaa
    27181 aagagttcgt cttcaaaaat agagcggtca agaatgttgt tatcggcttg ataagcttct
    27241 ttgatggact taaaccgttt attcaaaaaa taaatttgaa gtaaaaaggc gtacttttta
    27301 gggtcttggt agtagaggtc tagcacgggg ttattatcaa cagcttcgta aaaaacgtca
    27361 gttcctaaat gctctccaag tgcagcagca agcgagctct tgccagcccc aattgttcca
    27421 gctagtacaa tcaacatgcg tctccttcta atatcattag cgtactgttt cgaagatggc
    27481 ttcaacctca gctagagtct cagcgcgtga aacagcacca cgaactttgg cagcacctgc
    27541 tgttccacga agatagtgtg gcgctaagcc ccgaaattcc cgaacagcaa tggtttcacc
    27601 tttgaggtta atcaggcgtt tgaggtggtc tttggcgatg tctaattttt tggcaaaggg
    27661 aagatctggc aattcttgac cagtttcaaa gaaatgattg atttgggtaa aaagataagg
    27721 attgttcatg gctgcgcggc caatcatcac ggcatctaca ccgatttctt caatcataaa
    27781 tttggcgtct tgcaccgaac gcacgtcccc atttccaata aagggaatct tagtgatagc
    27841 cttagaaact cgggctaatg tctcatggtc gcaggttcct gtatacattt gttcacgggt
    27901 acgaccgtgc atggcaagag cagatacacc tgccgactca gcggcaaggg cattctcaac
    27961 ggcaagtgaa ctatccgccc aacctgtacg cattttgaca gtcagtggaa tatctaaaac
    28021 agacgtgact tccttgacaa tgtggtaaat cttatcaggg tcacggagcc acttggcacc
    28081 agcctcgttt ttgacaactt tattaacagg gcagcccata ttaatatcaa caatatcggc
    28141 cttggtattg gtttgaatga aatcagctgc acgtttcaac ccttctgcat caccaccaaa
    28201 taattgaatg gacatagggt gctcattctc gtcaatatgg agcatatgga gggtcttttc
    28261 gttgttgtag agcagccctt tttcggaaat catttccata accaccaaac cagcaccaaa
    28321 ttctttggcg atggtacgaa aggcagagtt ggtcacgcca gccatgggag caaggacagt
    28381 gcggtgaggg atttccacat caccaatcct aaaggaagaa ttaagcttta tcattgataa
    28441 tggcctccaa atcactttca ttaaattggt acttggtacc acaaaattgg caaacaatct
    28501 cagcaccctt atcttcgtca atcatggcct gtaaatctgc ttttggcaaa gtcattaggg
    28561 ctgcttcaaa acgttctcta gaacagtcac actgaaaact cagaggttct tcagaaagac
    28621 gcttgtaagg ttcatctcca tagatggcct ccaaaagggc atccacatga tttttggaag
    28681 ctagtaggtg agaaatggca ggcatttctt gcaggcgttt ttcatagcga gcaatctctt
    28741 cttcagaagc ttctggtagc acctgcacca taaagccacc agcaacctta accttatcat
    28801 tttcatctaa aagtacatta agtccgattg cagatggtgt ttgctctgat tcggttaagt
    28861 agtaggcaaa atcctcacca atttctccag taataagagg cgttgttgag gtgtaagggt
    28921 tacctgtgcc ataatcaata atcgtcacaa aatgaccatt ccccataaaa ggcccaacaa
    28981 ggacttcacc tgttgcggtc tttttaatat cgacaccagt attttgaatg taacctttca
    29041 catgtccttt ggtatctgcc acagagataa tgtgtccaaa agaagaatca ccaatcactt
    29101 tgacggtgat tttactatcg cctttttgat tagccgccaa aatctggttg gcgatcaagg
    29161 tacggccaag cgcaacagta gacgatgaca gcgtgttgtg tttttcttga gctaatgcaa
    29221 ccgtctcagt gctatcaagg acataagccc taaaagcccc tgattgtgct attgatttaa
    29281 ttattttatc cataacttag attatagcat aaagtgtaaa acttgtattg acaggattac
    29341 ttgaaaaatc aatacagata gacagtaaaa aatcccagag aatgactcgg gattaagtta
    29401 aggtgtggtc taaagtcgcg caatgtggtg acatggcgct tatgttaatt gcttggttaa
    29461 atcagcttgg aatttttcct ctttaacttg atatatcaat tcttggatag atagaatcga
    29521 ttcatcaaaa gatatttcag caacagcaat tccttttgta agctcatgtt gaacaaaagg
    29581 aatcagttgg ctgtgagtga tgaccaaatc tggctttaaa tcaggaattt gataaacatt
    29641 atcttgcaat aaataatagg aatgaaaatc aatgctttta tccgagaaat accttgggaa
    29701 agaatctgtt aggagatgag cattgataaa attactggct acgaaaacaa caactaaagg
    29761 aggttggata tttcttagaa tttgctcgac atagtggcaa aaaagatgaa aatgcttatg
    29821 gttcaagtaa cgcttaccag gaagtttgac catccactct tcgacaatta actttaagga
    29881 cgtatagagt ttttggtttc ctttatagta cggagaaatg aataagttgg tctcaggaat
    29941 aaaatgttgc agattaaaca agaatgattt tgaaaaaaac ataagagctt ttactaaact
    30001 agccttttgc tcttttaggt taggtaaaag agtgatgata ggatttaaaa gcaggcgaaa
    30061 agtatcattt tcttcaaaaa gttgacaaca ttgtctgata tgctcaggtg tccattgtaa
    30121 gctcgcaaaa gaattattag cggtgatata aattaaatag aggtagtcca aatctcctgc
    30181 tgaaaagttt agttggcagt aagtttcgat aatatcacgg ctactttttt tcaaagaatc
    30241 gtagacaaaa agttttttta attgttgaaa aattctggtt tggggaatag ttaccgaaaa
    30301 ttgatgccgc ttccacgata aagccaataa aatgtcatag aaagaaaacg attccgataa
    30361 ccaaggagag gttttaaggt gggtggaact atgggataaa aagctatgaa tagtgttttt
    30421 gtcttgctgc gtcaagtcat aaactttaat gccaaactta ctatatagca gagcgatgag
    30481 gtaacggatg cgatattcct caccgacaat cttgttctta gagagtttta attcaaagtt
    30541 tcttaataag ggaaccaatg cttcgcgcat ccgataagct gaggagtttg ataaaaaatg
    30601 acttctcgca aaatccgtaa ggggacgaga gtgtgaacca ttttttatta aaaaggctag
    30661 taattgtaag acattagatg atgcatagag ttggtaaaga taagtttctt taaaaggatg
    30721 tgtaaattgg caagatatca tccttttttg gatggtcata gacagactac cagggaaaaa
    30781 ggcattcagt tcctcacaat aatggtttag ttgtaaaaag gttaagccag ttttttctgc
    30841 tacctcagtt attgacaaat aagatgtctt aaaaaacaag acaattaact gacattttga
    30901 ttcgattgat gattccaagt atttttctat caaggaaagg ggtcctctct tcctacactt
    30961 agaaagccaa ataagtcttt gataagtgta ttctcctatt tcaattctat ctaagctaaa
    31021 aatagaaatc aaatctaatg gtttttggtg aaaagtcgaa accttttgaa atagctttaa
    31081 agcaatattt tctcaaaaaa tcattttcaa aaacactaat ttggtgaaat atacaatcaa
    31141 aaaaatatct ttcttgacaa taacatggta agctcatata tgtttgtgag aggagagaaa
    31201 atgaataaca aaatgttttt gaacaaagaa gccggttttt tggcacacac aaaaagaaaa
    31261 aggcgatttg ctgtcacttt agtgggagtc ttttttatgc ttttggcatg cgcggatgct
    31321 atccgttttg gtcaagtagc ctatgctgcc gatgagaaga ctgtgccgaa tcgtattaat
    31381 tcaaatcctg aatttccttg gtatggttat gatgcttata aaggatttga ggcaaggtat
    31441 catgatctta aagtcaattt aaagggaagt aaggaatatc aagtttattg ttttaattta
    31501 aaaagaagct ttcctcgccg cactcatagt attacaaata atttttacaa gaaaattgtt
    31561 gggagtggat cagtgttcaa atcttatgca gagaatccta gggttttaga tgagaattta
    31621 gataaattag aaaaaaatat actgaatgta atttataatg gatataaaag taatgcaaat
    31681 ggttttatga atggtataga agattttaat gctatactag taacccaaac cgcaatttgg
    31741 tattattcag atagctcccc agcatctgca actgcagttg aaaagatgtg ggacagagaa
    31801 gttaaggatg gggatatttc cttggagcaa gtgaaactaa tgcgtgaggc attgaaaaaa
    31861 ctaattgatc ccaatttaga agctactgca gttaataaaa tcccatcagg atatcgttta
    31921 aatatctttg agtctgaaaa tgaagattac caaaatcttt taagtgctga atatgtacca
    31981 gatagtcctc caatgccagg tgaagtacct aaagaggaga gtccaaaaga agagaacccc
    32041 aaaattccag atttagatgg gcgtgaaatc ccagaagttc cacaagaacc ttcagaccca
    32101 gttatcccac cagttatttt ggatggtgaa gaagttccag aagttccaag cgagagctta
    32161 gaacctgcgc ttcccccatt gatgccagag ttagatggtg aagaagtccc tgaaaaacct
    32221 agtattgact tacctattga agttcctcgt tatgagttta acaataaaga ccaatcacct
    32281 ctagcgggtg agtctggtga gacggagtat attaccgaag tctatggaaa tcaacagaac
    32341 cctgttgata ttgataaaaa acttccgaat gaaacaggtt tttcaggaaa tatggttgag
    32401 acagaagata cgaaagagcc agaagtgttg atgggaggtc aaagtgagtc tgttgaattt
    32461 actaaagaca ctcaaacagg catgagcggt caaacaactc ctcaggttga gacagaagat
    32521 acgaaagagc cagaagtgtt gatgggaggt caaagtgagt ctgttgaatt tactaaagac
    32581 actcaaacag gcatgagtgg tttcagtgaa acagcgattg ttgttgaaga tacgcgtccg
    32641 aagttagtgt tccattttga caataatgag ccaaaagtgg aagagaatcg ggaaaaacct
    32701 acaaaaaata taacacctat ccttcctgca acaggagata ttggaaatgt tttagccttt
    32761 cttggaatcc ttattttgtc agtactttct atttttagcc ttttaaaaag caaacaaaac
    32821 aataaagtct gacgtaaaag tgttccataa gaaataatgc gcaaatatgc tgaatagtgt
    32881 ataactgcta cagtcaagac aagtgttaat tcaaaaggta ctacttatac atctgataat
    32941 aataaggtga cagataattc agagcaagta ggatggctaa aaaatgatgt attctatgta
    33001 taatagactt acaagaaatc aagttattgt taaacgtcgt aaagcttaac gctttcaaaa
    33061 gtcgaaatca atcgagactg tctttaggca gtctcgattt ttaagtacga cgggcatgtc
    33121 ttacatctga ggtgcaaatc ctccgcggac acccgctacc ggtgaaccta atagcgactc
    33181 ccaagtctga ctatcgggaa gtagtgggga gaggaaggga gagtgaaatc gtggctctac
    33241 aaacagaaac gtgatatcaa ggcgtatata gcagatgagg aggcctgaaa ctctaaagtc
    33301 caaaaaggta gtcgtaacct ataggcgtaa atatgagagt aaacgaggaa agatgtacac
    33361 cttattcttt gaggtctcat gagcgttcta gacgtagtaa taacgaatga tgagaagtca
    33421 gccgatgcca tagtagcgat gaaacttctg taatggaagt agagcgaagg gctaaacaat
    33481 taaccgaagt atacctactt cacttgtgtc tgtaaaacta gtggtctgat agaactgggt
    33541 gtggtcacgt attgactaga ggaaagttca ctaatataag atgtccctca gacaccaaaa
    33601 taagaaagga atacgcaaag aggggtggaa aagtcgtcca catcaagata gagcgaccat
    33661 tgtcaattag tagcttaaaa gtcagttcta aaacaagcta tatcaaaaac agtcctcgca
    33721 aaacggggac tgttttcttg cttggatgac tacttagaaa agttcattga accgccgtgt
    33781 gccgaacggc acgtacggtg gtgtgagagg ggctagaaat tagcccctac tcgatttcta
    33841 tctaagctaa aaatagaaat caaattaaaa gactagaaaa taaatttcag agtgcttgga
    33901 aatatctcca aataaacatt tttctcaaaa gagaaagata attaaaggaa atatggtgat
    33961 ttttttcacc tccttatata ccggtaataa cgtatcaatg atatgatata accggttctg
    34021 gaaaaaagaa atggagagaa tttaatcaaa tgaaattgtc aaagaaatta tcaaagaaat
    34081 tatcaaagaa attattgtat tcggcaatgg cttttaccat gctgacaagt gccactgttg
    34141 caccagttgc tcagattata ccaagtagta cggtaagggc ggagactttg caggacagaa
    34201 cacaaaaaac gattccagaa gcaacagaag ttgtcattac taaattacag gcagatgact
    34261 ataatgatga tgtgaaacca aatggaaaag caaacgaaaa tggactgcca attaataatt
    34321 tgggagagtt aggaagaaat gtaaagccgc tttcagatgt tacatttgtg gcatataaga
    34381 taccagaggg tatagccgaa gaaaaagtta aagaactaaa aactaaacag acagtagtag
    34441 atgtagagaa ctatttgaat gcacaaaatc tcaaaattga gaaaactgta ttaactaaaa
    34501 cagatggaaa tggtcaaact acatttacag ttcaaaaatc tagctatggg aaatactttg
    34561 tagttgaaga tatgactgct actggaacac cagagacaat ctcgaaagcc tatgctgtac
    34621 cgtttacttt ggaacttccc atatctgctt cagatggcac aggttattta actaaagtta
    34681 atatctatcc taaaaatgtt acttctagtc ttccaaaacc gggtaaggat gtcaaagagc
    34741 ttggattaaa tcactctagc tacaatatag gagagagatt ttcttggttt ttaaaaggaa
    34801 ctgttccgaa gaatatgctc gattatgaga aatatagttt tactgataca ttagattctc
    34861 agcttgattt tataagcgtt aaatctgtta aatatggttc acaaatactt gagaagaata
    34921 atgattacac tctttctgaa ccaacggctc aaaataggac actgaaagtt gagttaacag
    34981 aagctggtat taaaaaagta gctggtttgt atcctgatag acaagaagtt ttagatacag
    35041 aaattgaagc tattaaagaa aatacagatc aaaaaccttt tttagaggta gagttcgaga
    35101 ctaatatcaa ttcaacagtt atcttaggga agccagttac taacgaagtt aagattgaat
    35161 ttgataataa acctgataag attgctaaac cagtaaccac tcctccttca gataatcctg
    35221 aagttcatac aggtggaaaa cgttttgtaa aggtggccgc agggaatgac gccactaaac
    35281 ttggtggtgc agagtttgat ttgttaacgg aagcaaatca accaatcaat tggactgctg
    35341 aattaattag agctaataat aaatcagaat atattgttgg cactcctcaa gaaggtcaac
    35401 cagttaaact aaaatcagat acggatggtt cttttgaaat taaaggttta gcgtatgcta
    35461 ttgatgcaga agctacggga gcaggagtta aatataaatt aaaagaaaca aaagcaccag
    35521 caggatatgt cattcctgaa gcgcctattg agtttgctgt gaatcaaaca tcttacaata
    35581 agactccaac taccatagat gttgataagg ccgatgcgga gcctcaaaag gtagaaaaca
    35641 acaaacgtcc tgaaattcca aatactgggg gtattggtac ggctatcttt gttgtgctag
    35701 ggattgttct gatggtagtt gctactaagg gtatgagaag tcacaaagaa gaaaactaaa
    35761 caaggctact tctaagtaac cacgctcaga aaagagaaat agccttattt ctcttttcgt
    35821 cgtttaataa aaaggaacat tatgcaaaaa ttattgaaat acctttgttc ttttggggtg
    35881 gttttgggat tgttgctagg ttttccggga caggttttgg ctcagggaga ccaggcccaa
    35941 ctaacggttg tacatttaga atcacgggat gtggatcgtc caaatcctca attggatttg
    36001 gctcccagtg ctgggaagcc ggttgaagga ataacgtatc gtctttacca gctcaaatta
    36061 ggacgagaag cccagcccat ttcttattgg gaaaagctga cgcttcaagc gttagaggag
    36121 caagcccaga cggtgtttga ggctaagaca gatgcgcaag ggcatgccgc ttttttacag
    36181 ctaccgactg gaatttatta cggggtagct gtggagaatc aacagcgtca agctggcata
    36241 gcaggcttct tggtagatct tacaggagat acgggttatg tgaagaccgt ttatcctaag
    36301 gttatttggc ctacaggtgg gttacacctt atcaaatacg gtgttgatgg gcaaactaag
    36361 gtacctcttg ctggggttag gtttgaactt tatgaggata atggatttaa acccttgcgc
    36421 gtgaaagatg ggcttcattc ttatgatttg gacgctaaga caacattaat cactaatcaa
    36481 gaagggcaac ttaaagtagc tggactactt gctggtaatt attaccttaa agaagtggcg
    36541 acggccaaag gttatcgcct gaaaacagat gctatttcat ttcaagtgca agcgcatcaa
    36601 accaagacgg ttagtgttga caaccaaaaa gaaccgcctc caccagtaac accttgggat
    36661 tggattccaa gaacagggga agcgcaggcg cttacgttaa ttgtgctagg gctcatctta
    36721 atgcttcttg ctttatttta ctatcaaaag catcgtcaag agggcaacga ttagcatgga
    36781 gacgtcaaag aaaaaggtgg agttgagggt ctggctgtca cgattagtat ttttagcagg
    36841 attcttagtt ttggcctttc ccattgttag tcaagttctt tattaccaag catcccgtgc
    36901 tgatattaac gcctttaagc aagctgttac taaaattgat cgcacggaaa tcaagcgtcg
    36961 tttggaactg gctagagcct acaatgccag tctatctgga ggaactaacc agacaaccaa
    37021 acctgttctg aaagaccctt attctgacca tcagaaaaaa gcagggcggg ctgaatactc
    37081 cagaatgtta gaagtcaggg agcagattgg ccatgtgacg attcctaaaa tcaaccagga
    37141 tcttcctatc tatgctggtt caggagagga aaatctgcaa cggggagttg gccacctaga
    37201 agggacaagt ttgccgattg gaggaccttc tactcatgcg gtcttgaccg ctcacagagg
    37261 tctgccaact gctagattat ttacagattt ggataagatg cgccgagggg atcgctttta
    37321 cattgaacac ttgggaggta agttggctta tcaagtggat agcatcaaag tgattacgcc
    37381 agatcgctta gatgagttat accttgttcc agataaggat tatatgacct tgctcacctg
    37441 tacaccttat atgattaata gccatcgtct ccttgttaga ggcaaacgca ttccttataa
    37501 ggaaagtctg aaacaaaaag atcaacagat cggtcagcga caccagttgg caacttatgg
    37561 cttcattgcc ttagggctta ccttagtgct agggttacta tggtatagga agcgacaaaa
    37621 gaaataaaat cggagacaag atgaaacaaa aggttaacca attataccaa ctaattgcta
    37681 ccaataagtt gaggagtgtt ctctttattt taggcatctt agtggtgtta tttccaattg
    37741 ttagtcaggc tagttattac cttgcctctc accaacaaat taatcaattt gaacataagg
    37801 cagcagttat tgatcgctct gctattgagc gacgaatcag cttagctaaa gcttacaatg
    37861 atgcgatttc tcggcatccc tctctgagtg atccttttac cagtaaggaa aaagcgggcc
    37921 tccgtgaata tgctcgaatg cttgaagtca atgaacaaat tggtcatgtt gctattccta
    37981 agataggggt tgatttgcct atttacgcgg ggacatcggc tgctattttg gaaaaaggaa
    38041 gcgggcactt ggaaggaact agtttaccga ttggtgggaa aaccacccat gccgtcttga
    38101 cggctcatag agggttacca acagctcggt tgtttacaga tttggacaag gtcaaaaaag
    38161 gtgattattt ttacgttacc aatttgaaag ggaccttggc ttatcaagtg gaccgtatca
    38221 tggtgattga acctagccaa ttggatgccg tgagcattga agagggtaaa gattatgtga
    38281 cccttctgac ctgtacacct tatatgatta atagccatcg cttattggta agaggtgtga
    38341 gggttccatt aacgtctaga caagccaaaa aagaaagctt aacagctgtg agaccatatc
    38401 agtattatcg ttggctagtg tacttggcca ttgcagttct gattatactt gtgatgattg
    38461 ttgccaaata ttaccaaaag actaataaat catcgtaata ttcattaggg tgttcataaa
    38521 cagcagccaa gagagagggc tgaaacttaa aggggaaagt gagtattgtg actaataaaa
    38581 cattacataa agtgcttgtc aagctagcag ccgttttggc tatactattt ttggtgttac
    38641 caacaggact gacagctgtg acagtacttg ccgaacaaat caacacagaa aatcttatcc
    38701 cggtagaaac cgctgctggg gaaatactaa aagaaagtga tcttgatttt gaacaagcta
    38761 ttccaacatc aggggaagct ctcaaagata gttcagccag ctggatacag ctgacctata
    38821 ataaggttaa tcaaaatcta gctaagcaag atctcttttt aagactgcct caaggcatga
    38881 caattgaggg gattggtcaa gaccagaagc ttgatgttaa gaccatttcg gtgcctaagg
    38941 atcttgattt ggacgaagca gcttcaacta tcaataatac taacatcatc actgggtttg
    39001 aaaaaatagg agagcaagac tataaactta gctttgccgc aacatcaaaa acccttaatc
    39061 ttgtgttcaa ggttaagggt accagcctta atgagaaaag agagcttcag ctgagtgata
    39121 aacagaacct taaccaaact agctttacta aaaaattagg tctaggcatt gcaaaaagtg
    39181 acgatagaac aagcgcaaac gacaccacca caagaccaag tattcaacca agagcagcaa
    39241 ctgctcgaga gacaactggt aatcaagaca tcagtgcaaa tctaaccact tctaatgctc
    39301 agttaaactt agaagataag gataagaata atatttatga cgtcgaggca ccagactcat
    39361 ttatgtttag agcaactctt agtttgttag atagtcgtta tatcgttcct gggaattact
    39421 ttgagctaaa attatcagat acgattcact acaatatgct gaacccaaca gatattaatt
    39481 tcccatattt aacacaagat ggaaaagtga ttgctgtgcc agaattagtt caggatccac
    39541 ccgttgatgg tcttttgaga gcaacgggaa aaatcgtccg ctatcgcttt acagatcaag
    39601 tccaagggct ggattcatta actatgacct taaacttagg tcattcagtt aatcctaatg
    39661 tggttcaaaa taatgataag tatgattttt cttatcagat aggtgggcat attataaagc
    39721 agagttatga tgtccaatat gggaagccta aagaaaatgg taacctaaat gttcatcaac
    39781 gcttaacata taccgactcc aagcaaaatc ttaaagccag tagtctgata tatgtgaatc
    39841 ctaaacaaac accacaatat gctggaaaac aaacgttatc aattttaaga aatccaaaaa
    39901 cttatacgat aagtgaacaa acggttccta atttactgga gctaaataac caaacgagta
    39961 tcaaagttta taaattgaag gattcaaaag gagttacgga tgcggttaat cttgacaaac
    40021 aatatttgga agaagtcatt aatccgataa ttactaaaag tgacggtaag attgaggttt
    40081 cctttaacta tacacaaggt gaaacatcgg cttatgttgt tgccgtggag acaagtcttc
    40141 aacaagaagg aagccaacct gtctttattg ctcagaattc caatctaacg agtgctagta
    40201 caaggaagaa agtgtctgaa acagatgcca ctgcaaccgt tggtagcggt ggctctgcat
    40261 caggtgacca gacgccaaaa gggactcttt accttaacaa ggtagataca aatcacaaac
    40321 acctcgccaa tgccactttt accctttcag gaaatacgac tgcaggtcaa tttctttatc
    40381 gcacattgat aacagatact aaagaagtta gcttttctga cttacctcct ggttcctatc
    40441 tattaaaaga aacaacagct ccatcgggct atcaacaaat aacgacgcca tggacagtaa
    40501 cggttgacga caaaggaaaa gtgacagtta caggtaatga agcagacacc caaaaagttc
    40561 ccgaagaagc agaagttgtg attttgtggg aatctacaaa atggaattac ggcaatgttc
    40621 agttttataa ggacaggttt aaggaattag ttgattctgt aggaaatcaa aatgctaagt
    40681 atacccttat tcgttatagt ggagatacta gtgatagtgc tcaggttata aatcagtcag
    40741 tctcttctgc agaatttaat aaaattctta atagtgagac attaacagct agtacaatga
    40801 ccaatcggaa gggaatgcta aaagcttatc agctagcact gcagcagttt caagcaagta
    40861 caaataagcg aaaatacctg cttcagttga cgaattaccc tatttatcct ggttacagag
    40921 aagaaaagga ttttatgtct caaagtcaga caagctttga tgctatgaag tctttgggag
    40981 ttgttcctta ccttcttgta gaacgagacc cttacgctaa tcgaaatact tacttagatc
    41041 cgaaagctga ggcatcttca tttggagctt tttacccatc agacaatatc aaagtggtat
    41101 ggtccaataa ttctagtgga ttatttacac ctccaactaa tacaaactac actattcaaa
    41161 tccaatctat tggttctgcg attaagcaac aaatccccga atctgtgtta accgttatta
    41221 acagagcatc tggtaagttc agcattaaca agattgacga agctaaaaaa ggcttagcag
    41281 gtgctacctt caccttgtct aaacgtacaa cagtagcggt aaatcatcaa gtacaagggg
    41341 ctttcactcc tgtcagcaaa gagacaacag ccggtcgaac aacccttacc tttgacaacc
    41401 ttaaacctgg agtttatgat cttaaagaaa cgaaagcgcc gaatgcttac gtgcttgatc
    41461 ctaagactta tgttgtggtc gttcaaaatt caggaaaaac gacaattgtg gatgaagcta
    41521 acttcaaaga ggctgattac ccaatggctg ataataccag ccagtttgac tacccaacca
    41581 aagatattgc caataaacca aataagattg tatttactaa aattggtgat ggcggcaagt
    41641 ctttgagtgg agctgaattc gaattgcgta aggggaacga gaaagtccaa actaccacat
    41701 caggtgctga tggtaaggta acctttagca aattacttcc aggaacttat gaagtttggg
    41761 aaacgagagt tgctgacagt gcttatcaac ttccacaaga agcagtagca acttttgagg
    41821 ttaaagctga tggaactttc tcagaaccta tgggacggtt gtttaggaaa aacatcgctc
    41881 aaaataaccg ttatgaaatt cgcaacgagt tggtcaataa aaaaacgggt aatcaaaaaa
    41941 tcaaggtcat caaaaaagat gagctgactg atttaccact cccaaatgct aaattccagt
    42001 tagaagcgtc agatggaaca atttatacca aaacgacaga tgtgaaaggt gaaattgttt
    42061 ttgagaagct tccttacgga cagtatattt taactgaaat tgaagcacct tcaggatatg
    42121 tgctggatcc aacaccgcat aaaatcaatc tgacggaagt agatagtcct gaaacagaag
    42181 tagtggcagg tagaaatgca acacagccaa cagtagcacc aacagctaga gcagctttgg
    42241 cggctcctgt ggcagagcca gtgacaggaa aaaatgtttc tgatcaaatc agcattaaag
    42301 aacttgatat tacctcatcg aatgaagata cgccacgtct tgtaaggcct aatcatggag
    42361 agaatattgt gatgcgggca ggctttacaa tcaatccagg tagtgatatt aaggcaggag
    42421 acttttttac cttaactcta ccgaatacca ttgatccttt tggagtttcg gcgccagaaa
    42481 atgttgattt tagaatattg ggtcctctag gaacactcgc attgggaact tatgattcta
    42541 gtactcacac cattacctac aaatttacag attatattac tcggtatacg gtatcgtctt
    42601 ttagcacaat ttcgccattc tttattgacc gagacagggt taaaaccaat caagacattg
    42661 atttattctt aaaagttggt caagtatctt cgacctcata tcattttaca gttgattata
    42721 atccttatta cggtacggcg gataccaata atcctgtgaa cgttggctct atgataacca
    42781 gactaaacca ggatactggt gattttgtga actatattta cgttaaccca gcaggtcaaa
    42841 ctctggaaca agctacatta acgtttacag gtcgagggtc aactcgtatc gatgcaaaca
    42901 caagagtaca actttttgaa gttactaatc ctaaacttca aatgccacca agttggggaa
    42961 ttcaagacga gacattaaga gaggtggacc ctgctaatta tcagttgata aaggaaaatg
    43021 gacgtttcac aattaatttt tataatgatc ttttgtacgg tcgatcttat attgttaagg
    43081 tgagtggcaa gtcagataaa aacgatccag atccgattca tacatccgct attttgacac
    43141 agcgttattt taatgattat ccctactata ccccatctgg acgttatatt ccatatggtc
    43201 cctataccga atcattcacc ttcactgcag aggttgtcaa aaaatcagga gaaagtaatg
    43261 ctgacgggtc tgttgtggtt agattatcaa accgtaagaa ttacattgac tttatgaagt
    43321 ctaattctca aggaactcca cttgaagcta cctttgaatt gcgtaaaaaa gctaccaacg
    43381 atacggtaac agttggaacg ccagtaattt ctgacaagac gacagggaaa ttctattttg
    43441 aaggactttc accaggtgac tatgaagttt gggaaaccaa agctccagac ggttatacca
    43501 agccagttga agcggtggcg acctttaaag taactgatga aggagagatt gttgacaaga
    43561 gtcttgaaga tggtcgtatc attaactata ggagaccaga gctaccggca acaggtgggc
    43621 ctggaatatt cgtttacctc ttcatcggta gtgctatgtg tttggtagcc atcttttggg
    43681 accactcctt tcggtttacc aaataaattg ctttaaacag tcaaaaatag gcagagcctt
    43741 aaaaggtttt ctgccttttt aatcttgttg ggtacttacg aaagtatttc ggccacttca
    43801 agcataataa aaagagtctg agcaatcatg ttgtctcaga ctctgactgt aattatgcaa
    43861 aagatgatgg actggcagct tcatttactc accgaactcc cctttataac ttgggaatga
    43921 tgctgctaat gggttgtttt gtttaatgcc tgctataaac ggtaatttat cccatttatt
    43981 tttataatct tcttcaagct cagttttaaa cttccaaacc attttatgag aaaaataagt
    44041 gtgtgattga cggccatagg tgtctactaa aacgtgagaa aattttcctt cgttttttag
    44101 tttgtaaaat ttatctagag aaggactcca gccagtataa ccagggaatt tatcaaattc
    44161 ttgattaaaa tttgtttgtt ggctttccca atcataatgc cattttgtat tcctgcgtgt
    44221 tttagaatca actgtaccgt cccaataatg atgctcataa gttatctcct taggagcttt
    44281 tacaccctta ggaagaaaca ctgagaaatc agggtaaacc cattgttctt tagctgaatt
    44341 aaaggttaca gtccattcga tactgttatt gttatcgacc aatgttttag tatagtcgac
    44401 atagttatca acatagtaat ttccctgcca gtaaaggtgc actttacctt tctcatcaat
    44461 gttatcatgg gcatgtactg atttatacga actaaacagc atcgaagctg ctagtagtga
    44521 agtgaagaga tatttattat atcgtttcat atcatgaaaa acctttcttt taatactaaa
    44581 tatattatat caaaaaaaac tgaaaagtaa attatttttt aattttttat cataattatt
    44641 taattattta aatataacaa agacattgtt gatgagtgaa gcgccattct ttttgctata
    44701 aataagggtt atggaagcaa taaaaaaatc atagttgttt gtttatgaaa acgttgtcat
    44761 aataaaaagg gaacaaaagt gttttttgtg ggtttaaact tattgataac taaatgaact
    44821 aaagaaacgc ttattagtat tatcgatagg ttactgatta aaagaacaaa agtgcttgtg
    44881 gacaatgtga aaggaattga caacatgaat aacatcaaaa ccaaaaaaag gtttatggat
    44941 cgctatattg atggctttat gaaatggatg ccagaatcgc tttttatctg ttttatttta
    45001 acctttttag tcgttactat gtctgtgttg atgacggata gtccctttat tggtacggaa
    45061 aagacgggcg gaattatcta tggctgggta aatggttttt gggggctgtt gtcctttgcc
    45121 atgcagatga ctattttact tgcgacaggg aatgctgtag cgagttctcc acctgctcat
    45181 aaaatgttta agtcccgtgc caaactgcct caaaccagga ctcagatttt tattttttct
    45241 attgtagtag gctctatctt tggcttttta cactggggtc ttggtatgat ggttgccatt
    45301 gtgtttggga aagagttact tgttcaggct aggcaaaaag ggattaaggt gcatacacct
    45361 ttgtttgttg ctactttatt ttttaccttt ttaccagcta cttctggttt atctggtgct
    45421 gcggtgcttt attcggctac tccagattat ttgcgaaata gtgtcgcaga tgcttataaa
    45481 caggttgttc ctgaaagtgt tcctctgaca gaatcagttt tgaatcttcc atttatcagt
    45541 cttttagtgg tgtgtatgct ggtaccgctt tgctttgctt tattggcgca cccaaaagat
    45601 gaaactaaaa tcatggaact tgatgatgag atctatcacc atagtcttga taccgcttca
    45661 catgttgtta ttgcaagaaa cacacctgct gagaagatga acgcatctcg cttagtgatg
    45721 tatcttgttg gtggggccat tgttagctat agcctttatc atttttcggt ggtgggcttg
    45781 tctggtctag atctcaatag ttttaacttt ttatttttag gcttagggtt gcttctttgt
    45841 ggtcaacaag gaccagaata ttatggttcc ttattcaaag atggggtcat gtcatcttgg
    45901 ggcttggtgc ttcagtttcc attttacgct ggtatttttg gaatcattca aagtacaggt
    45961 ctaggactag agatttccca tttctttgtc gctatttcaa atgggacaac atggccggtc
    46021 tttgcttatc tttactcggc tttgctgaat attgcggtac catcaggagg ctcaaaattt
    46081 gtgattgaag ctccctatat cgtccctgca accatcgaag ttggtaatga cctaggtaag
    46141 attttgcagg cttatcaatt aggagatgcc acaacaaact tgatagttcc tttttgggcc
    46201 ttatcttacc tctcaaactt caaactaaaa ttcaatcaaa ttgtggctta tactattcct
    46261 tgtgtcttgg tggtcacagg tattgcgatc atttacctat ttgtatttta ggaaataact
    46321 atatgaaacg cttgggattg tttccttcag gcgttttttt taaggtctga gtcaagcaat
    46381 tagaagcgct ggttcgtgaa ataatctaag atggtgtgct tgatataatg ttttaaatgg
    46441 cttgttttat tgtgcttgag agaggctaga acaacttccc attttggatg ttcggtcagt
    46501 tggacctcca ctaaaccgtc catatgagca aaatgagtaa taggtcttgg taggattgtt
    46561 aggtaagagg aatagcgcgt gcaatttaat aaaaaatccc acgaggcaga ataacatttg
    46621 actacaggaa gactatttgc ttcttcaaat aaggtggtaa gctgatgatt aatcataaag
    46681 gttttgtcaa aagttactaa gttttgacga tgtaatgctt tgatagagat gttaggatta
    46741 ctatcaaacg tctcttgaaa ggttttgtga ctcatataaa ggcagagttg atctcttagg
    46801 agaatgtcga tatcagcaat agtagcatct agtgtagtgg gtgttaataa aatcgcaaaa
    46861 tcgacttctt ttagaaacag ttttttttgc agttcataag cacccgtttc tacaatatga
    46921 aatttaactt cgggattttc ttcgatgagt tttggaatga gctcagaaaa aacaatgcca
    46981 gagatgagtt gaggaatacc gattgaaatt tctcctttgt attttttgga ttcactccgc
    47041 aaatcagcca ttaattgctc atgtgatgcg ataaccacct tagcattttc aaaaaagtgt
    47101 tcgccgactg aggttagtcc aactagacgc cctttttgac gctggaataa aacgactcct
    47161 tcttcttttt cgatagtctt gatataacta ctaagggcgg gttgcgaaat atgacttttt
    47221 tgggctgctt tggttaagtt aaagtcacaa ttaacaatct caataaaata agccaagctt
    47281 gaaatattca tattttcctc tttcgataac gcttagttat agcatatata aaaaaacgat
    47341 atttgtttat tatagttcac attatataat aaaaatgtaa gcgtttcaat aatgaaaaag
    47401 gagaagtttc tatgactaaa gaagtggtga tcacatctgc ttatcgtacc ccgataggaa
    47461 attttggagg agtctttaaa tctttgtcag ccgtagattt gggtgtgaca gttgttacaa
    47521 aaattttagc tgataccggt cttaaaagtg atgccattga tgaagtgatc tttgggaatg
    47581 tgttacatgc aggtctgggt caaaatgttg ctcggcaagt agcactaaat gcggggcttt
    47641 cttatgatac ccctgctttt acgattgata tggtctgtgg ttctggctta aaagcagttg
    47701 agttaggtgc tcaaaagatt caaacgggca acgctgatat tgttttagtt ggtggtaccg
    47761 aaaacatgag tcaagcacct tacgttttac aaggccaacg ttggggatct cgtatgggag
    47821 atagtaaagt agtagatacc atgcttaaag atgggttgag tgatgctttt gcaggttatc
    47881 acatgggtat aacagccgaa aatattgtgc aacagtatgg actgaccaga gaagaacaag
    47941 atgcctttgc agctgatagc caacgtaaag cccaacttgc catagaaaaa ggtcgtttca
    48001 aagaagagat tgcacctgtc actattcctc agcgtaaagg tgaaccttta ctcattgatc
    48061 aagatgaata ccctaaattt ggaacgacag tggataagtt agcaaagtta cgccctgctt
    48121 ttatcaaaga tgaggggaca gtaactgctg gtaatgcttc aggaatcaat gatggagcag
    48181 cggcaatttt attgatgagt aaagaaaaag ctgaagaatt agagctccct attttagcta
    48241 aaatcactgg ttatgcaagt gcaggtgtag acccaagtat tatgggctgc ggaccaatac
    48301 ctgctacgaa aaaggctctt gcaaaggctc agctgacaat tgatgacatt gatttgattg
    48361 aagcaaacga agcttttgct gctcaggctt tagcggtttc acgagacctt ggttttgaca
    48421 atgaaaaagt taatgtcaat ggaggagcta ttgctttggg tcacccgatt ggagcatcag
    48481 gtgctcgtat tttagtcacc ttattagcag aaatggctaa gcgtgatgtg agacatggct
    48541 tagcaacgct ttgtattggt ggtggccaag gtcaaagtat catcgtaaca agatagaagg
    48601 taaccgtatg aaagagaata aaagaatagc aatagcagaa gctatcagtc atattaaaga
    48661 tggtgacacg attatggtcg gtggttttat ggctaatgga acaccagaag cgttaattga
    48721 tgcactggtt gacaaaggca caaaagactt aaccttgatc tgtaatgatg ctggttttgt
    48781 tgatcgcggt gttggaaaaa tggtggctaa tcatcaattc aaaaccattt atgcaacaca
    48841 tattggatta aataaagaag ctgggcgcca aatgactgcc ggtgaaacga cgattgagct
    48901 cattcctcaa ggaaccttcg ccgaaaaaat tcgcatcgga gcttatggca ttggtggctt
    48961 ttacacgcca acaggggtag gaaccttagt ggcagaaggc aaggaaacaa aaaccatcaa
    49021 gggaaaaacc tatctcttag aatacccatt tgaagcagat gtcgccttga tatttgctaa
    49081 taaagctgat gaaatgggaa atttacagta tagtggttct gaaaataatt ttaatcaatt
    49141 gatggcagct tgtgcaaaaa caacaattgt tcaggcgcga gaaatagtac cagtcggcac
    49201 catacaacca gaatgcgttc atacaccaca catttttgta gattacattg ttaaagaagg
    49261 agtatagtta tggcggttgc attaagtaaa gaagagattc aaaatcgtat tgcaaagcgt
    49321 gtggccaaag aattagaaga tggtactttg gtaaatttag gtattggtct accaaccaaa
    49381 gtagcaaatt ttgtgcctga agaaatgaca gtgtattttc aatctgaaaa tgggtttatt
    49441 ggactaggtc ctaagtcaga tgatccgaat tcgactatcg ttaatgcagg aggacagcct
    49501 gtgacggttt atccaggagc ctctttcttt aatagtgcag attcttttgg cattatacgt
    49561 ggtggtcatg ttgacttgac cgtcttgggt gctttagaaa ttgcagaaaa tggagatatc
    49621 gccaattacc tgattccagg caaaatggtt cctggtatgg gaggagcgat ggatttatta
    49681 gttggtgcta aaaaagtcat cgtagctatg gagcatacca ataaaggaaa gcataagctc
    49741 ctaaaagaat gtaccttacc tttaacagca aaaggtgtgg ttgaccttat tatcacagaa
    49801 atgggtatgt ttaaagtaac gccagatggt atccaagtaa ttgaaatcag tgaagggttt
    49861 acttttgatg aggttcaagc tgcgacaggt gtacctctaa gcatagctga aggttaatga
    49921 ctagtagcct tttcttgcca taaaggcata ttgagtaaaa aaaacgtcag tcatcggtat
    49981 atcagagatt gtgatgctta tctgaaatac ttttaactgg cgttttatgg tgatttagtt
    50041 attgatcggc ttcaattttt ttaaggtagc ggtaaacact tggttcggaa atacatagaa
    50101 tatcagcgac ttttgagacg gctcctttta gttgaaagac tcctttttca taaagcttgg
    50161 caacaatgtc tattttgaca tcttggctaa gatgtacatt gtgtctcagt aacgagggat
    50221 caataatttg accgataata tcttggatgt tagaggttaa aatttcaaca gcttcttctg
    50281 gctggggtgt gactgtttta ggttctttag cagttgggat gaaatgttct aaattgagat
    50341 tgacaagttt taagaggtcc ctagctactc cttgataggc tgaaatatct aagttaatac
    50401 atagcattcc ctcgagatta ccctttttat ctttaataaa aaaagtagat ccccgaactt
    50461 ctttgtgctg aggactaacg attgctttgt aattggtcac aaaatctttt tccttataga
    50521 ctttattggt aatcaaatca agagcaaagg tggtgagagg agactgttta gaccgtccac
    50581 tgatatgact attaacgagt tctccaatat agatatcatt tttatcaatc acatgtaaaa
    50641 taatctcata gttatcacct aagacatcgt gaagaaatgt gataaccgtt ttccagtagt
    50701 ttagcgtttc tttatccatg tcaaacttcc tatatctatc ttcttattta caaatatagt
    50761 aatacatttt agactaaaaa acaattgcca atcaccttaa taataatttt ttatcaaaaa
    50821 gagaatttat tattgactgt gaatgcggtt tcctgtaaaa tttaactata ttatcaatga
    50881 ggaggttcgt atatgaagag ctacccagaa ccaatgggcc cttattcaac ttatacgatt
    50941 gaaggacatt ttctatacac cgcaggccaa ttacccctta atccagtgac aggtcaattg
    51001 tcagatggtt ttgaggcaca gtgtcgccag gtttttgtta atttacaatc tattttggca
    51061 gagcaaaagt tggacttgaa tcatatctat aagctaaatg tgtatttaac agatgtgacc
    51121 aatgtggaaa tattaaatca tgtcatgact gatttgtttg aagagcccta ccctgttcgg
    51181 acagcggttc aagtatcggc gcttcctttg caagctttga ttgaagtcga agctgtcgcc
    51241 agagtgaagc agttatagtg tcttatgtaa tgagatagat tggtggaata gattatggat
    51301 attattattg gaacaagtct tttgattctt gttttagcta tttttagctt gtttaactat
    51361 aaggctcctc atggtgccaa ggcaatggga gctttggctt cggcagcttg tgcctctttt
    51421 ttagttgaag cctttcaaga ttcttttttt ggtaaggttt taggctttca gtttctaagt
    51481 gaagtaggcg gagcaaatgg ctcattatca ggggtagctg ctgctatctt ggttgccatt
    51541 gcaattggtg tgtctccagg ttatgccgtt ttgattggtt tgtcagtttc aggaacaggt
    51601 attatcccag gttttgtggc tgggtatgtg gtatcttttt taatcaagtg gatggaaaaa
    51661 aatattcctg gtgggcttga tttaatctcg attattattg tcggtgcacc attaactcgt
    51721 ttcttggcgc agttaattac gccagtgatc aatagtactt tattgactat tggagacatc
    51781 ctgacctcaa gtgctaatag caaccctatt atcatgggaa tgatactagg cggtacgatt
    51841 gttgttgtag caacagctcc gctgtcatca atggctttga cagccatgct tggtctgaca
    51901 ggtattccga tggctatagg tgccttatct gtctttggct cttcttttat gaatggtgtt
    51961 cttttttacc gattaaaatt gggtgaaaga aaagacaata ttgcttttgc tattgaaccg
    52021 ttgactcagg cagatgtgac gtcagccaat cccattccga tttatgtgac taattttgtt
    52081 ggtggtgctg catgtggtgt tttgatcgcc ctaatgaaat tggttaatga tacgccaggg
    52141 acagctactc cgattgccgg ttttgcggtg atgtttgcct ataatcctgt cgctaaagtg
    52201 ttgataacag cccttggatg tattattatc agcttaattg tgggttatat tggaggttct
    52261 gtctttaaaa attaccgttt agtaacaaaa caagaattac aagcgagaaa ctaataaaca
    52321 tctttttgac aggactttta acaagatagc agttatactg ttatcacatt ggcttggcta
    52381 ttggctggta aaggttcctt accgtcaacg agatcaaggt tactaaatgc ctaaagaagt
    52441 ataagataac acacgaaaga cagcaataca aagctttaga gttctgtgtc atcttactgc
    52501 tttgacaggt ttttagctaa cctttttctg aactaagcca ttgtttttat ggatagaatt
    52561 gaaagcgctt aacttacaga tgctgttcgt ttaatcaagc cattatccta tctcaaaaaa
    52621 gttgttagta gataggttag agatttagct ctagcttata ttcgctggtt gattaacccc
    52681 ccaaaagtag cctttcttgt agctttgttt ttaagtacct agtgagtcaa agaattagca
    52741 atagataaag ataaggagtt gatatgtgat gaatacccta ttgtcactaa tgaatagtat
    52801 cgaacaagag gctagaacaa tttatgacag ttacgatgct aagaaaaaag ctctagctga
    52861 caaaaaagaa gaagagttaa agcagctgtt ccttgagtac gaacaagaaa ctcagctact
    52921 attagaagct aaacgtgagg tgttttttga agctaatcgt caagaacaaa aagcttcaaa
    52981 aaagaggtta gcgacgcaac agctagctct tcatgccatt ttagaagagc ataagctaac
    53041 cgttgttagg gagttagtgg ataaggtggt ggagacatat ggccattagt caaatgaaaa
    53101 agctggcaat ggtttttgaa aaagattatc ttgatcttgt tttaaaaaca cttcaacaat
    53161 ctcaattagt tgaagttcgt gacatgaagc aactaaaaca ttggcaagat gcttttaaca
    53221 aaggcaacgt caagttgcca caaatcgtcc aatacgatct gacgcatcaa aaacctctac
    53281 tagatgatga agctttacaa taccttttac aaagccaaca agagttagaa aacggccttg
    53341 ctagcttatc agcgttttta ccatcaatag gaaagttaac agccttgaga caaaaaacgc
    53401 catctctttc gtttaaacag ttcgaagaac gccatcgaca acaagcagct caaacggctt
    53461 tgaaaatgat gtcacaaaag atagagcgac tagagcagct gcaaagcaaa atagaccagc
    53521 taacagaata ctgtcaggag ttagaaaagt ggcgttcctt gactgttttg cctcaggact
    53581 tagcgcaatt tcattttttg tcggcaagag ttggaacgat tcctagtaca gcaaatgatc
    53641 atttttatca tcagctaaag cagcacaaag gtctttttat tgaggaagta taccatacag
    53701 aatttgagta cggccttgtc ttattttggc aagcacaaga tacgattcat ttacagaaat
    53761 atcagtttaa acccttatta tataaagaac agctactgcc atcagaacaa cttcgtataa
    53821 acaaagagtt actaacgaat tggctagctg aaaaagatag tctactaaaa gagcttaggc
    53881 agtctcaaaa gatactggca cagttacagg ttgaaataga ctatgtcctt agtcagtatc
    53941 aacggcagca aactaaaaag caattactcg gtacaagaca tctaatagcc ttagaagggt
    54001 ggatagaagc tgattcggtt aaccaattaa aagggctaat gactaagaca ctaggtgata
    54061 tgttttatct ggatagttac gatgtcacgc cagacgattg ggaagatgtt cccattaagt
    54121 tacgtaatca ccgctacatt gcaccgtttg aattggttac agaaatgtac gctttgccaa
    54181 aatatcaaga aaaagatccg acaccttttt tagctccttt ataccttact ttttttggca
    54241 tgatggtagc tgatttgggc tatggtttgt tgctatatgc tgtgacacta gctgcattgg
    54301 tcttttttaa tctccaaaaa accagtaaac ggttagtgac cttctttaat attttagcta
    54361 tttcagtagc cctttggggg cttatttacg gttctttctt tggttttgac ttacctgtgg
    54421 cattattatc aactaaaacg gatgtgatta ctattttggt tgtttctttg ctatttgggt
    54481 ttgttacact tatatttggg cttttgttag gagcatggca acaagtaagg atgaaagcat
    54541 atgctacggc ctatacgtca agtctagctt ggacttttat tttattaggc ctgctgttat
    54601 ttattcttgg taagaatgta tctggccttg cttacttatc ggttattggt aagtggcttg
    54661 cattgggcaa tgcctttggg attttggttg tttctttact aaaaagcaaa agccttttag
    54721 gtctaggtag tggattatat aatttatatg gcattagctc ttacttaagt gatttggtta
    54781 gctttactcg tctaatggca ttagggcttt ctggagctag tattggagcg gcttttaaca
    54841 tgattgttgg gatttttcca ccagtcacgc gctttacagt aggtatcttt atttttattc
    54901 ttttgcatgc gatcaatatt ttcttatcaa tgctttcagg atatgtgcat ggtgctcgtc
    54961 ttattttcgt agagtttttt ggaaaatttt atgaaggtgg aggaaaagct ttcaatcctt
    55021 taaagttagc tgataattat gtcaatgtca atgaagaaac agatttggag gacaattaac
    55081 atggaacatt tagcacatta ttttacagca catggtggcg ttttcttcgc agccttagga
    55141 attgttttag ccgtagctct tagtggcatg ggctcagctt atggtgtcgg taaaggtggt
    55201 caagcggcag ctgcgctctt aaaagaagaa cccgaaaaat tcacgtctgc gcttatcttg
    55261 caactgttac ccggtagtca aggaatctac ggctttgcta ttggtatttt aatttggatg
    55321 aaactgacac cagaactttc agttaaccaa ggattagctt actttttggt atctcttcca
    55381 attgctattg ttggttattt ttcggccaag caccaaggca atgtttctgt agctggtatg
    55441 caaatcttgg ctaagcgccc taaagatttt atgaagggtg tcattttagc agctatggtt
    55501 gaaacctatg ctattcttgc ctttgtcgtc tcctttattc tcttaaataa aattggataa
    55561 ggtaacggtc cttatctaga ttttaaaaaa cggtgacacc actaacacta tcaaaagggg
    55621 gaaattaggt gaatgatata atacagttaa gacaaaatgt tcttgaaaaa gcacatcaag
    55681 aaggtcaaca gtgcctaaag atagcgacag atagtcttga tactgacttt aaagagcgtc
    55741 aacagcaagg actacacgat ttaaaagcaa agcgtcaaaa agagttaaaa gctcttgaac
    55801 agcaatttca ggttgcgcag cagcaactca aaaatcaaga aagacaagct ctactagcat
    55861 taaaacaaga cagtataaag gagctatttg aagcttcttt ggagaagatg acgaactttt
    55921 ctaaggaaga agaattggct tttttgaagc aagtcttgtc taaatatcca gaacagccat
    55981 tgcaagttac ttttggcgaa aaaacagggc aaaagttcag ttcttatgat tgtgctgagc
    56041 tgagattagc atttcctcaa ttaagctata atcaagagct aattcctcag gaagcaggat
    56101 ttttagtcag tttagaccaa gtcgatgaca attatttata ccgttacctt ttagaatcag
    56161 ttcttaaaga agaaagctcc cgcatcattg atatgctttt ttcagagata taggaggttt
    56221 gactagcgat gccaacattt ctagaattaa acactactat cagtgtcaaa gaaaaagagt
    56281 tattgactaa agagcaattt gataagctat tgcaggctcc caatacaaca accttagctc
    56341 gactgttgca ccagtcagtc tatcacctaa ctgttgacga tctcaacgat ttggatcggc
    56401 tagaatctat cttaatggct gagctaacca agacctatcg ctgggctttt gcagaaaccc
    56461 ctcaacctga catagtacaa ttatttacct tgcgttacac ctatcataat gtcaaagtgt
    56521 tgttaaaagc taaagctagt caagcagatc tgagtcactt attactacca attggtgaca
    56581 agcctctggt ggctttggaa catttgatta ggacgatgac ttctgatgag tttccaaaag
    56641 aggtggtaac agaaatccag tccatttggg ccgaatatca agattatcaa gacatacgcg
    56701 tcttagaaat tggtactgac ttagcttatt ttaaggcgtt gaaacaaata gcacaaagat
    56761 tagaggaccc tgttttccaa caagctgttc ttattgtgat tgatttgtat aatctgatta
    56821 ccgtcagacg ggccaaatcg caaaataaac caataagttt catgatgcag ttattatctg
    56881 atgaagcaag tagaccaagt aaaacattta tcacacttga agatgataag gatctgatga
    56941 cgtggtttga aaatgtaaca cctgatagct atatgacagc cctaaaacct tattcagaga
    57001 aacttcgcca aggcactctt caaacgactg agttagaata ccttgttgat gaatgccttt
    57061 accatttatt tgcgaaggcc aaatatcaag tcgatggacc ttatgtgctt gctcgctttt
    57121 tgctcgctaa atcgtttgaa gtaaaaaatc tacggctttt agcggctgct ttagctaatg
    57181 atttacccaa agaacgtgtc atagaaagga tgagaccaat agcatgacca aaacattgta
    57241 taaagtcggg gtaattggta acagagatgt tattttacct tttcagatga ttgggtttca
    57301 aacttttcca gtaataaaac cacaagacgc tattaaccag ttgcgtcaac tagcaatgga
    57361 agactttggt attatttata tcacagaaga tattgctgca gctattccag aagccctcac
    57421 tcactatgac aatcaagttc taccagcagt cataccatta ccaactcatc aaggaacgca
    57481 agggataggc ctgtcacgca tacaagccat ggttgaaaag gctgtcggtc aaaatatttt
    57541 ataacactaa gacgttatgc aaagaggact tatactctgt ttgaggctta tgagtagcta
    57601 actgatgaaa tgcaaggaca ggaaaattgg tgaagttagc agctgaacgc ataggatagt
    57661 ttgctgacta ttcaaaatag tcacattaaa ccttgacagt atagattagt tagtatgatt
    57721 tggaaaaaat aaaggaggaa aaaggtgaac caaggaaaaa taataaccgt ttcgggacct
    57781 cttgttgtgg cttctgggat gcaagaagct aatattcaag atatttgtcg tgtgggacat
    57841 cttggcttag tcggagaaat tattgaaatg cgccgcgatc aagcgtctat tcaggtttat
    57901 gaggaaacat cagggatcgg tccaggagaa ccagtagtga ctactggttg tcctttgtcg
    57961 gtcgagttag gcccaggcct gatttcagaa atgtttgacg gtattcagcg accgcttgat
    58021 cgttttcaaa aagcaacgga cagcgacttt ttaatccgtg gtgtggctat cccaagtctt
    58081 gatcgaaagg ctaagtgggc atttattccc aagctaagtg ttggtcaaga agtagttgca
    58141 ggtgatattt taggaactgt gcaagaaaca gctgtcattg agcatcgtat catggttcct
    58201 tataaagttt cagggacctt ggtggctatt catgcaggga acttcacagt aacagataca
    58261 gtttatgaaa ttaagcagga agacggttcc atttaccaag gtagcctcat gcagacttgg
    58321 ccagttcgtc aaagtcgccc tgttgctcaa aagcttatcc cagtcgagcc tttggttaca
    58381 ggtcaacggg ttattgacac ctttttccct gttacaaaag gtggtgccgc tgccgttcct
    58441 ggaccatttg gggcaggaaa aacagttgtg cagcatcaaa tagctaaatt tgccaacgtt
    58501 gatattgtta tttatgtcgg ttgtggggaa cgcggcaacg agatgaccga cgttttgaat
    58561 gagtttccag agttaattga cccaaataca ggccagtcca ttatggagcg cacggtgtta
    58621 attgcaaata cctctaatat gccagtagca gcgcgtgaag cgtcgattta cacaggcatt
    58681 actattgccg aatatttccg tgatatgggc tattctgtgg ctatcatggc agactcgaca
    58741 tcacgttggg cagaagctct gcgcgagatg tcaggacgcc tacaagaaat gcctggtgat
    58801 gaaggctacc cggcttactt agggagtcgt attgccgaat attatgaacg ggctggtcgt
    58861 gttcggacct tgggaagtca agaacgtgag ggaaccatta cagccatcgg cgcggtttct
    58921 cctcccgggg ggggatattt cagagcctgt cactcaaaac acccttcgga ttgtcaaagt
    58981 tttctggggg ctcgacgcgc ctcttgcgca acggcgtcac ttcccagcga ttaactggct
    59041 gacgtcttat tcattgtatc aagatgatgt aggaagctat attgaccgta aacaggaatc
    59101 taattggtcc aacaaggtaa ctcgtgccat ggctattttg cagcgtgaag ccagtctaga
    59161 agaaattgta cgcttggtgg ggcttgattc actgtctgaa caagatcgtt tgaccatggc
    59221 tgttgcccgg caaattcggg aggattatct ccagcaaaat gcctttgatt cggtggatac
    59281 ctttacttcc tttccgaaac aagaggccat gctaaccaat attttgacct ttaatgagga
    59341 agccagcaaa gccctttctt tgggagctta ttttaatgag attatggaag gcactgctca
    59401 ggtacgcgat cgcatcgcac gcagcaaatt tatcccagaa gaaaacttag agcagattaa
    59461 agggcttact cagaaggtta ccaaagagat tcaccacgtt ttagcaaagg gaggaattta
    59521 gatgagcgtt ctcaaagaat atcggacggt tagcgaagtg gttggccctt tgatgattgt
    59581 tgatcaagtt gcaggagtgc actacaacga attggtagat attactttgc ataatggaga
    59641 aaggcgtaaa ggtcaagtct tagaagtcca aggtgacaag gctatggtac agctatttga
    59701 aggatcaact ggcatcaacc tagccaaaac caaggttcga tttacagggc atcctttgga
    59761 attagccgta tcagaagata tggtagggcg catctttgat ggaatggggc agcccataga
    59821 tggcggtcca gaacttattc ccgaaaaata ccttgatatc gatggtcaag cgatcaatcc
    59881 tgtcgctcgt gattacccag acgaatttat ccagacaggt atctcagcta ttgatcacct
    59941 caataccctc gttcgtggtc aaaagttacc agttttttcg ggctcagggt tacctcataa
    60001 tgaattggcc gcacagattg ctcgtcaggc aactgttcta aactctgatg ataactttgc
    60061 ggttgtgttt gcagctatgg gtattacttt tgaagaggca gaattcttta tgaatgactt
    60121 gcgtgaaacg ggtgccattg atcgatctgt tttatttatc aatttggcta atgaccctgc
    60181 tattgaacgc attgcaacac cacgtatagc tctgacaaca gccgaatact tggcttatga
    60241 aaaaggtatg catgttttag tcatcatgac agatatgaca aattattgtg aagccttacg
    60301 agaagtatca gccgctcgca gagaagttcc aggcagacga ggttatcctg gctatctcta
    60361 tactaatctc tccaccttat atgaacgggc tggtcgcttg atcgggaaaa aagggtcagt
    60421 gactcaaatt cctattttaa ccatgccaga agatgacatt acccacccta tccccgattt
    60481 gacaggttat attaccgaag gtcagattat tttgtcgcaa gaactatata aaaatggttt
    60541 tagaccgcct attaatgtct tgccatcgct atctcgccta aaagataaag gctcaggtga
    60601 aggtaagact cgacaagacc atgctgccac aatgaatcag ctctttgcag cctatgccca
    60661 aggaaaacaa gctaaggaat tggctgttgt gctcggtgaa tcagcccttt ctgaaacgga
    60721 taaactatat gtggccttta ccaaccggtt tgaagaagaa tacattaacc aaggatttta
    60781 caccaaccgt agcattgaag aaagtcttga cttgggttgg gaattgttgt cgattttgcc
    60841 acgtaccgaa ttaaaacgca ttaaagatga tatgttagat cgttatttgc ctaaagcaga
    60901 taccacgatg acaaaggttt ttgttgcaaa tgattgagtt gaccatgcaa tttcaagccc
    60961 ttgacgaaag gagttatatc aatggcacga ttaaatgtta aaccaacacg catggaactt
    61021 agtaacttaa aaaatcgatt gaagacagct acaagaggtc ataaattatt aaaggacaag
    61081 cgggatgagt tgatgcgccg cttcgttgat ttaattcgtg aaaacaatga gcttcggcaa
    61141 actatcgaaa aagaacttgc tgccaatatg aaggagtttg tcttggcaaa agcatctgaa
    61201 aatagtctaa tggtagaaga actctttgct gttccagtcc atgaagtgac cttatggatt
    61261 gatattgaaa atatcatgag tgtcaatgtg cctaaattcc atgtccagtc taatacggca
    61321 agagagcaag aacaaggtga gtttgcttat agttacctca gctcaaatag tgagatggac
    61381 aatactatcc aaaagacaaa agaactatta gaaaagctct tacggttagc tgaagttgaa
    61441 aaaacttgtc aactaatggc tgatgacatt gaaaagacta gacgtcgcgt caatggctta
    61501 gagtattcta ttatcccgca actggaagag acgattcact acattgagtt gaaattagaa
    61561 gaggccgagc gtgctagcct tgttcgtatt atgaaaataa catcataaaa gataagtgtt
    61621 atatcaaaca aggcgattat tcgttaagta gtaaaaaagc aagccatcaa agggattaac
//
LOCUS       DATTYN010000007        59407 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.07, whole genome shotgun sequence.
ACCESSION   DATTYN010000007 DATTYN010000000
VERSION     DATTYN010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59407
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.07"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            105..215
                     /locus_tag="VB649_000609"
                     /pseudo
     CDS             105..215
                     /locus_tag="VB649_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_129544913.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            467..2686
                     /locus_tag="VB649_000610"
     CDS             467..2686
                     /locus_tag="VB649_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEP1669582.1"
                     /translation="MAKIMNVTGEEVIALAATYMTKADVAFVAKALAYATAAHFYQVR
                     KSGEPYIVHPIQVAGILADLHLDAVTVACGFLHDVVEDTDITLDEIEADFGQDARDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNETEFYKISHMMKEKRREREALV
                     EAIVSKVKTYTTQQGLFGDVYGRPKHIYSIYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKANGYQSIHTTVYGPKGPIEIQIRTKDMHQV
                     AEYGVAAHWAYKKGVRGKVNQAEQAVGMNWIKELVELQDASNGDAVDFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKESGPIDFAYAIHTQIGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIITNANSFGPSRDWVKLVKTNKARNKIRQFFKNQDKELSVNKGRDLLVSYFQEQGYV
                     ANKYLDKKRIEAILPKVSVKSEESLYAAVGFGDISPISVFNKLTEKERREEERAKAKA
                     EAEELVKGGEVKHENKDVLKVRSENGVIIQGASGLLMRIAKCCNPVPGDPIDGYITKG
                     RGIAIHRSDCHNIKSQDGYQERLIEVEWDLDNSSKDYQAEIDIYGLNRSGLLNDVLQI
                     LSNSTKSISTVNAQPTKDMKFANIHVSFGIPNLTHLTTVVEKIKAVSDVYSVKRTNG"
     gene            2701..3144
                     /locus_tag="VB649_000611"
     CDS             2701..3144
                     /locus_tag="VB649_000611"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEP1669583.1"
                     /translation="MKLVLQRVKEASVSIDGKIAGAINQGLLLLVGVGPDDTAEDLAY
                     AVRKIVNMRIFSDADGKMNQSIQDIKGSILSVSQFTLYADTKKGNRPAFTGAAKPDLA
                     RQLYDSFNEQLAEFVPVERGVFGADMQVSLINDGPVTIILDTKCH"
     gene            complement(3241..4563)
                     /gene="ska"
                     /locus_tag="VB649_000612"
     CDS             complement(3241..4563)
                     /gene="ska"
                     /locus_tag="VB649_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023611186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptokinase"
                     /protein_id="HEP1669584.1"
                     /translation="MKNYLSFGMFALLFALTFGTVKPVQAIAGPEWLLDRPSVNNSQL
                     VVSVAGTVEGTNQEISLKFFEIDLTSRPAQGGKTEQGLNPKSKPFATDKGAMSHKLEK
                     ADLLKAIQEQLIADVHSNDGYFEVIDFASDATITDRNGKVYFADRDDSVTLPTQPVQE
                     FLLSGHVRVRPYQPKTVHNSAERVNVNYEVSFVSETGDLDFTPSLRDRYHLTTLAVGD
                     SLSSQELAAIAQFILSKEHPDYIITKRDSSIVTHDNDIFRTILPMDQEFTYRVKNREQ
                     AYGINKKSGQKEKINNTDLISEKYYVLKKGEEPYDPFDRSHLKLFTINYVDVDTNKLL
                     KSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFGIMDYTLTGNVEDNHDDTNRIIT
                     VYMGKRPEGENASYHLAYDKDRYTEEEREVYSYLRYTGTPIPDNPNDK"
     gene            4903..5751
                     /locus_tag="VB649_000613"
     CDS             4903..5751
                     /locus_tag="VB649_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEP1669585.1"
                     /translation="MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKER
                     LLLEVGLGQCEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQALPADLVELLQ
                     QMIAGLEVILPISATQTAFLCRQAISIKVLRWLEDLLPTLESDFGLALTMFVGNAWYQ
                     VAAGTLRECFEEECQLLTAYLRQQSGRKLLTFSGLMLWSLLSHHTFLALTRQFHQFLS
                     PQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAH
                     LFLLKY"
     gene            6049..7182
                     /gene="ugpC"
                     /locus_tag="VB649_000614"
     CDS             6049..7182
                     /gene="ugpC"
                     /locus_tag="VB649_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEP1669586.1"
                     /translation="MVELNLNHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIGGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVEVKDGRIVSEDGLAIAIPEG
                     QAKMLEAAGYKGKKVTFGIRPEDISSRQIVHDTYPSATVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHSPGEQVSLTFNVAKGHFFDRDTEQAIR"
     gene            7311..8924
                     /locus_tag="VB649_000615"
     CDS             7311..8924
                     /locus_tag="VB649_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEP1669587.1"
                     /translation="MKKHWWHKATIYQIYPRSFKDTSGNGIGDLKGITSQLDYLQKLG
                     ITAIWLSPVYQSPMDDNGYDISDYEAIAEVFGDMADMDELLAAANERGIKIIMDLVVN
                     HTSDEHAWFVEARENPNSPERDFYIWRDEPNDLTSIFSGSAWEYDNASGQYYLHLFSK
                     RQPDLNWENEALRHKIYDMMNFWIAKGIGGFRMDVIDLIGKVPDLEITGNGPRLHDYL
                     KEMNQATFGNHDVMTVGETWGATPEIARQYSRPENKELSMVFQFEHVGLQHKPDAPKW
                     DYAKELDVPALKAIFSKWQTELKLGEGWNSLFWNNHDLPRVLSIWGNDSTYREKSAKA
                     LAILLHLMRGTPYIYQGEEIGMTNYPFKDLTEVNDIESLNYAKEAMGNGVSAARVMDS
                     IRKVGRDNARTPMQWSKDTHAGFSKAQETWLPVNPNYQDINVADALADPDSIFYTYQK
                     LIALRKEQDWLVEADYHLLPTADKVFAYQRQLGEETYVIVVNVSDEEQVFAKDLTGAQ
                     VIITNTDVDTVFETKHLQPWDAFCLKLKA"
     gene            9122..12619
                     /locus_tag="VB649_000616"
     CDS             9122..12619
                     /locus_tag="VB649_000616"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEP1669588.1"
                     /translation="MKKKVNQGSKRYQYLLKKWGIGFVIAATGTVVLGCIPSILTHQV
                     AAKTIVGLARDEAQQGDGNAKSGDGFQSSSKEAKPVLDSSSANPASIAEHHLRMHFKT
                     LPAGESLGSLGLWVWGDVDQPSKDWPNGAITMTKAKKDDYGYYLDVPLAAKHRQQVSY
                     LINNKAGENLSKDQHISLLTPKMNEVWIDENYHAHAYRPLKKGYLRINYHNQSGHYDN
                     LAVWTFKDVKTPTTDWPNGLDLSHKGPYGAYVDVPLKEGANEIGFLILDKSKTGDAIK
                     VQPKDYLFKELDNHTQVFVKDTDPKVYNNPYYIDQVSLKGAEQTTPNEIKAIFTTLDG
                     LDEDAVKQNIKITDKAGKTVAIDELTLDKDKSVMTLKGDFKAQGAVYTVTFGEVSQVA
                     RQSWQLKDKLYTYDGELGATLAKDGSVDLALWSPSADTVKVVVYDKQDQTRVVGQADL
                     TKSDKGVWRAHLTSDSVKGISDYTGYYYLYEITRGQEKVMVLDPYAKSLAAWNDATAT
                     DDIKTAKAAFIDPSKLGPTGLDFAKINNFKKREDAIIYEAHVRDFTSDKALEGKLTHP
                     FGTFSAFVEQLDYLKDLGVTHVQLLPVLSYFYANELDKSRSTAYTSSDNNYNWGYDPQ
                     HYFALSGMYSANPNDPALRIAELKNLVNEIHKRGMGVIFDVVYNHTARTYLFEDLEPN
                     YYHFMNADGTARESFGGGRLGTTHAMSRRILVDSITYLTREFKVDGFRFDMMGDHDAA
                     AIEQAFKAAKAINPNTIMIGEGWRTYQGDEGKKEIAADQDWMKATNTVGVFSDDIRNT
                     LKSGFPNEGTAAFITGGAKNLEGLFKTIKAQPSNFEADAPGDVVQYIAAHDNLTLHDV
                     IAKSINKDPKVAEEEIHKRIRLGNTMILTAQGTAFIHSGQEYGRTKQLLNPDYKTKVS
                     DDKVPNKATLIDAVAQYPYFIHDSYDSSDAVNHFDWAKATDSIAHPISNQTKAYTQGL
                     IALRRSTDAFTKATKAEVDRDVTLITQAGQDSIQQEDLIMGYQTVASNGDRYAVFVNA
                     DNKTRKVVLPQAYRYLLGAQVLADTEQAGVTAIAKPKGVQFTKEGLTIDGLTALVLKV
                     SSKTANPSQQKSQTDNHQTKTPDGSKDLDKSLMTRPKRAKTNQKLPKTGEASSKGLLA
                     AGVALLLLAISLLMKRQKD"
     gene            12864..13814
                     /locus_tag="VB649_000617"
     CDS             12864..13814
                     /locus_tag="VB649_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEP1669589.1"
                     /translation="MKQKNINKLVCRYGLTTAAAILATFGGVANVRANAESMQYVGKD
                     LEKTLEKDYENYVPKINNSREGRDPSKPVNIEDYLARIQEYLEARKRDDYEWKDKITK
                     SIQNGTFQGDKGDMGPEGKPGPKGDKGETGGQGPRGERGETGLQGAPGERGEQGPAGP
                     KGDKGERGEKGETGATGAQGPQGEAGKDGAPGEKGEKGETGAQGPAGPKGDKGERGEK
                     GETGATGAQGPQGEAGKPGEKAPEKSKEVTPAPEKPADKEANQTPERRNGNMAKTPVA
                     NNHRRLPATGEQTNPFFTAAAVAVMTTAGVLAVTKRKENK"
     gene            14026..14373
                     /locus_tag="VB649_000618"
     CDS             14026..14373
                     /locus_tag="VB649_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HEP1669590.1"
                     /translation="MTFEEIVANFIPSSVAEVTSAIASGKDMIVFLGRSSCPYCRRFA
                     PKLAQVATDNQKEVYFVDSENAADAAELAAFRENYQLVTVPALLVSYDQHQRAVCDSS
                     LTPDDILAFLTRE"
     gene            14489..14854
                     /gene="yajC"
                     /locus_tag="VB649_000619"
     CDS             14489..14854
                     /gene="yajC"
                     /locus_tag="VB649_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEP1669591.1"
                     /translation="MGFPTILMFVVMLGLIWFMQRQQKKQAQERQNQLNAIEKGDEVV
                     TIGGMFAIVDEVDTTAKKIVLDVDGVFLTFELSAIKRIVTKATTETTLVETEETIVVN
                     EPAVETVDSTDTDSAIESH"
     gene            15073..15822
                     /locus_tag="VB649_000620"
     CDS             15073..15822
                     /locus_tag="VB649_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEP1669592.1"
                     /translation="MFGLKAKSTKKVLGSIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHEN
                     NVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFY
                     FTPVLWPDFKKAELLKAIADYNRRQRRFGKV"
     gene            15835..16629
                     /locus_tag="VB649_000621"
     CDS             15835..16629
                     /locus_tag="VB649_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEP1669593.1"
                     /translation="MKERVVWGGVAVAIFLPFLIIGNLPFQLFVGVLAMIGVSELLKM
                     KRLEVFSFEGVFAMLAAFVLAVPMDHYLTFLPIDANVAFYSLMVFFILAGTVLNSRAY
                     SFDDAAFPIATSFYVGIGFQHLINARLSGIDKVFLALFIVWATDIGAYLIGRQFGRRK
                     LLPTVSPNKTIEGSLGGIACAVLVSFIFMVIDRSVYAPHHFLTMLVLVALFSIFAQFG
                     DLVESALKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            16702..17961
                     /gene="rseP"
                     /locus_tag="VB649_000622"
     CDS             16702..17961
                     /gene="rseP"
                     /locus_tag="VB649_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEP1669594.1"
                     /translation="MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKTGTPASLTLNEQGFVKRINLSQS
                     KLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGL
                     RDNDQIVAINGYKVTSWNDLTEAVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHA
                     KTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLITGFSLNKLGGPVAMYDM
                     SNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEA
                     YITLAGVAIMVVLMIAVTWNDIMRVFF"
     gene            18159..20015
                     /locus_tag="VB649_000623"
     CDS             18159..20015
                     /locus_tag="VB649_000623"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEP1669595.1"
                     /translation="MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPART
                     DLDRWVVLDKSIASMDDIPKEVLEEIKAELAAWMISGEDTIAYSSESSYAANLEMATN
                     EYKPSSKVAAEDALTEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVG
                     NDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLT
                     NAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFK
                     LGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH"
     gene            20269..24666
                     /locus_tag="VB649_000624"
     CDS             20269..24666
                     /locus_tag="VB649_000624"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEP1669596.1"
                     /translation="MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFH
                     FAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAP
                     CNSASFKSSFSKLKVTYENDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGTLTID
                     MVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKER
                     AAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     ALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLM
                     PEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSIL
                     VAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSL
                     DHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLAT
                     GNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFA
                     FLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKACPKCGTPYQKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAS
                     WQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGY
                     IDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLDAVKARMEDITIKRKNNEGTNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGAS
                     STLVEKMDEMGILGNMPEDNQLSLFDDFF"
     gene            24776..25204
                     /locus_tag="VB649_000625"
     CDS             24776..25204
                     /locus_tag="VB649_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP1669597.1"
                     /translation="MSHLDKNTALKAMVVFRKAQRTLDAFGADIFKKADLTATQFSVL
                     EVLYTKGCMRINHLIDSLLATSGNMTVVLNNMERNGWISKCKDKTDKRAYVVTLTDKG
                     TRLIEAVLPKHVARVEEAFAVLTEKEQLCLIELLKKFKQL"
     gene            25335..25877
                     /locus_tag="VB649_000626"
     CDS             25335..25877
                     /locus_tag="VB649_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEP1669598.1"
                     /translation="MKHILFIVGSLREGSFNHQLAAQAQKALEHQAVVSYLNWKDVPV
                     LNQDIEANAPLPVVDARQAVQSADAIWIFTPVYNFSIPGSVKNLLDWLSRALDLSDPT
                     GPSAIGGKVVTVSSVANGGHDQVFDQFKALLPFIRTSVAGEFTKATVNPDAWGTGRLE
                     ISKETKANLLSQAEALLAAI"
     gene            complement(25911..26525)
                     /locus_tag="VB649_000627"
     CDS             complement(25911..26525)
                     /locus_tag="VB649_000627"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEP1669599.1"
                     /translation="MSAQDKLIKPSHLITMDDIIREGNPTLRAVAKEVSLPLCDEDIL
                     LGEKMMQFLKHSQDPVMAEKLGLRAGVGLAAPQIDVSKRIIAVLVPNLPDKEGNPPKE
                     AYSWQEVLYNPKIVSHSVQDAALSDGEGCLSVDRVVEGYVVRHARVTVDYYDKEGQQH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFETKEELLILD"
     gene            complement(26626..26895)
                     /locus_tag="VB649_000628"
     CDS             complement(26626..26895)
                     /locus_tag="VB649_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP1669600.1"
                     /translation="MTQNVCQQNITYTVKERFASYTLEAQANQEVHLNLTLLANRFGT
                     SDRHLKHVLKQPIFQRIIERICFKTYRIADLDALTQLRPLRYAAH"
     gene            27021..27221
                     /locus_tag="VB649_000629"
     CDS             27021..27221
                     /locus_tag="VB649_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669601.1"
                     /translation="MTMLGYRLSAEVLGSAILPLLAGYLIRQAIAQVYSDLKTAYWLF
                     GLASSVAYGGLVKAKRAHSTTR"
     gene            27395..27664
                     /gene="rpsO"
                     /locus_tag="VB649_000630"
     CDS             27395..27664
                     /gene="rpsO"
                     /locus_tag="VB649_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEP1669602.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNSHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            28016..30076
                     /locus_tag="VB649_000631"
     CDS             28016..30076
                     /locus_tag="VB649_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEP1669603.1"
                     /translation="MLSHELIRNYQLFSKYKGHSLEAFESILKTSKRHILADIAKIND
                     TLSLYQLPLIALDRQLVYPPDLTEKDLLNRMLPTLDDYLFQNERLDMIIIYIMMAKEF
                     ISINHLESLLRLSRNSVIADLNLVRDRVQAFQVTLAYNRQDGYFFEGEPLALRRLLES
                     AVSSLLQVTSGPWVFSYLLHELGLPDQKKVMAATLEELSRENHLTFISEKLRDLIYFF
                     CLLAHRPFSRNVRAEAVDTFPLASPAVETMVDQLLVNFPSLTEEKYLVQSRLLGCIQG
                     DLELVFQQPIYDIMEEIINSVAVNTGLSITDTPELRQNLYSHLLPAYYRLYYDINLTN
                     PLKEQIKQDYESLFYLVKRSLSPLEKQLGKLVNEDEVAYFTIHFGRWLQAPKKRPSNQ
                     LVALSVCPNGISSSLMLEATLKELFPQLQFIRIHQLDKIKLLDPASFDLIFSTVAFDC
                     AKPVYVTQALMGPVEKMMLKKMVCDDFHLPLSEQFALDDLLSIIHKHTTITNKEGLVS
                     DLSRYLIGNHLTIEKGGLGLLDLLTADFIRQADAVSDWQEAIRLAAQPLLEHQMIETS
                     YIDGMIDSVNELGAYIVLAPKVAVPHAAPKKGTRQLGMSLLQLKEPVSFDLKQEGDPD
                     KQVQLIFVLSAVDSSSHLKALQELSLILDDDEHIEQLIEAKNTEEIMSLISHMIEKGD
                     ESHD"
     gene            30069..30353
                     /locus_tag="VB649_000632"
     CDS             30069..30353
                     /locus_tag="VB649_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP1669604.1"
                     /translation="MIKIVTVCGNGIGSSLLLRMKVEAIASSLGIDVDAESCDSNAAV
                     GKGADLFVTVKEFKDIFPEDAKVCIVKSYTNRKKIEEDLVPVLKEMSGKE"
     gene            30380..31759
                     /locus_tag="VB649_000633"
     CDS             30380..31759
                     /locus_tag="VB649_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEP1669605.1"
                     /translation="MEALLSFIRDILKEPAFLMGLIAFAGLVALKTPAHKVLTGTLGP
                     ILGYLMLAAGAGVIVTNLDPLAKLIEHGFSITGVVPNNEAVTSVAQKILGVETMSILV
                     VGLLLNLAFARFTRFKYIFLTGHHSFFMACLLSAVLGAVGFKGSLLIILGGFLLGAWS
                     AISPAIGQQYTLKVTDGDEIAMGHFGSLGYYLSAWVGSKVGKDSKDTEDLQISEKWSF
                     LRNTTISTGLIMVIFYLVATVASVLRNASVTEELAAGQNPFIFAIKSGLTFAVGVAIV
                     YAGVRMILADLIPAFQGIANKLIPNAIPAVDCAVFFPYAPTAVIIGFASSFVGGLLGM
                     LILGVAGGVLIIPGMVPHFFCGATAGIFGNSTGGRRGAMIGAFANGLLLAFLPAMLLP
                     VLGKLGFSNTTFGDVDFGVLGILLGRLGTSIGQIGIYLVVAVLAIVLVLPNFLSKSQE
                     AINNVSEEI"
     gene            31769..32500
                     /locus_tag="VB649_000634"
     CDS             31769..32500
                     /locus_tag="VB649_000634"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HEP1669606.1"
                     /translation="MMTKKLNVKVFSDGAVLETMLKDLQTGLVTGFTTNPSLMKKAGI
                     SSYIGFAKEVLAKITDYPVSFEVFADDLASMEKEAEKIASLGDNVYVKIPVTTSTGES
                     TCPVIQKLSAKGIKLNVTAIFTIEQTQAVVDHLTAGVPAIVSVFAGRIADTGVDPMPI
                     MEEALRICRQKEGVELLWASPRETYNIYQADQLGVDIITCTTDLIAKLPLQGKDLEDY
                     SLETVQMFLKDSTSLGFKILEDDNQ"
     gene            32780..34912
                     /gene="pnp"
                     /locus_tag="VB649_000635"
     CDS             32780..34912
                     /gene="pnp"
                     /locus_tag="VB649_000635"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEP1669607.1"
                     /translation="MSKQTFTTTFARKPLVVEVGQVAKQANGATVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLVDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFNGPIAGVQVGYIDGEFI
                     INPDKEQMEASLLELTVAGSKEAINMVESGAKELSEDIMLEALLKGHQAIQELIAFQE
                     QIVAVVGKEKAEVELLQVDADLQADIVAKYNAQLQKAVQVEEKKAREAATEAVKEMVK
                     AEYEERYAEDENLATIMRDVAEILEQMEHAEVRRLITEDKIRPDGRKIDEIRPLDAVV
                     DFLPKVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLAPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALEQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTREGITAL
                     QMDIKIAGITPQILEEALAQAKKARFEILDVIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDDEGNVSIYSSDQAAINRTKEIIAGLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWTRTTNVSDVLEVGEDVDVKVIKI
                     DEKGRVDASMKALIPRPPKPEKKEEKHD"
     gene            34905..35657
                     /locus_tag="VB649_000636"
     CDS             34905..35657
                     /locus_tag="VB649_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEP1669608.1"
                     /translation="MTKSNELDIRLRAFINAPDNFLDSLALVNAFHNFPVWAAKEPYV
                     IEVEGVKVTPVFTDKEDMARFKEEQKSAQSQYWLERSALAVLDEVITSGAAGLVFNLK
                     KKGDFGNSTIFKSSDMIQFMNHYTTVLNTLMSDDNVAADTMEKVYLVPAFVYPKDDNH
                     YDRLFPTMSTPEGKSYVPAFSNLQSFAKWYNQDDFGGLFRKAEGVILTWTIDDIYQPR
                     NGENELDETFGVAINPFDDQQILVDWSELDKS"
     gene            35666..36247
                     /gene="cysE"
                     /locus_tag="VB649_000637"
     CDS             35666..36247
                     /gene="cysE"
                     /locus_tag="VB649_000637"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEP1669609.1"
                     /translation="MGWWKESIAIVKALDPAARNSLEVILTYPGIKALAAHRLSHFLW
                     RHHFKLLARMHSQFWRFWTQIEIHPGAQIAPGVFIDHGAGLVIGETAIVEKGVMLYHG
                     VTLGGTGKDCGKRHPTIRQGALISAHAQVIGPIDIGANAKVGAAAVVLSDVPEDVTVV
                     GVPAKIVRVHGQKDNRQIQSLQKQREVSYQLSK"
     gene            36726..36956
                     /locus_tag="VB649_000638"
     CDS             36726..36956
                     /locus_tag="VB649_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669610.1"
                     /translation="MNKIRVGLYVIMSLSILVSSITLVASLIFLLRQDMVKAIIYFIL
                     TLFWLIGLVINIKLLKRWNSISEKDLGYQDDN"
     gene            36984..38327
                     /locus_tag="VB649_000639"
     CDS             36984..38327
                     /locus_tag="VB649_000639"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEP1669611.1"
                     /translation="MIKIYDTMTRSLRKFVPLTENTVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYTGYQVNYISNFTDVDDKIIKAATQAGVSPKELSDRFIAAFIEDTKA
                     LGVKPATQNARVMDYIAEIISFVESLIEKDFAYEADGDVYFRVEKSEHYAKLANKTLS
                     ELEVGASGRTDAETALKENPLDFALWKSAKAGEVSWDSPWGFGRPGWHIECSVMATEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVTVDNEKMSKSLGNF
                     VTVHDMLQTVDGQVLRFFLATQQYRKPINFTEKALHDAEINLKYLKNTLQQPLTETAD
                     EQELKQFVIAFQDAMDDDFNTANGITVVFDMAKWINSGSYTEPVKSAFEKMLAVFGII
                     FEEEVLEVDIEALIAKRQEARANRDFATADAIRDQLAAQGIKLLDTKDGVRWLRD"
     gene            38320..38733
                     /locus_tag="VB649_000640"
     CDS             38320..38733
                     /locus_tag="VB649_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEP1669612.1"
                     /translation="MTNPVDVNLINGIALAFEGDAVYSYYVRRHLIFQGKTKPSQLHR
                     LATRYVSAKAQANLIQAMLEAQLLTEKEEDIYKRGRNTNSHTKAKNADIITYRMSTGF
                     EAIMGYLDMMGQKERLEELIRWCIEYVEKQQLISS"
     gene            38929..39725
                     /locus_tag="VB649_000641"
                     /pseudo
     CDS             38929..39725
                     /locus_tag="VB649_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            39772..40518
                     /gene="rlmB"
                     /locus_tag="VB649_000642"
     CDS             39772..40518
                     /gene="rlmB"
                     /locus_tag="VB649_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEP1669613.1"
                     /translation="MEDKDTIETNDIVYGVHAVTESLQANTGNKLYIQEDLRGKKVDN
                     IKSLATQKKVAISWTPKKTLSQMTDGAVHQGFVLRVSAFAYTDIDEILEIAEQEANPL
                     ILILDGLTDPHNLGSILRTADATNVCGVIIPKHRSVGVTPVVSKTSTGAVEHIPIARV
                     TNLSQTLDKLKARGFWIFGTDMNGTPSDCWNTNGKLALVIGNEGKGISTNIKKQVDEM
                     ITIPMNGHVQSLNASVAAAILMYEVFRNRR"
     gene            40522..41040
                     /locus_tag="VB649_000643"
     CDS             40522..41040
                     /locus_tag="VB649_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEP1669614.1"
                     /translation="MKKRILLVDGYNMIAFWQSTRQLFKTNQLDQARNTLLTKLNHYA
                     HFENINIICVFDAQYVPGLRQRYDQYYISVVFTEEDETADSYIERMAAELNTAIHMVE
                     VATSDLNEQWTIFSQGALRVTARELEQRVHTVKADLDKMSRDIDLKTPKLRPFDQGQL
                     IQLKDFMSQLDR"
     gene            41137..41997
                     /locus_tag="VB649_000644"
     CDS             41137..41997
                     /locus_tag="VB649_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP1669615.1"
                     /translation="MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNR
                     ISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHAKNNKALLYLAFSSVLSGTYQSALM
                     ARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLR
                     TYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEM
                     VAQVEKDIADSTVIVSYTSDQGSAEKLREELLVHENISDVLMMPLGPVISAHVGPNTL
                     AVFVIGQNFR"
     gene            42133..42831
                     /locus_tag="VB649_000645"
     CDS             42133..42831
                     /locus_tag="VB649_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669616.1"
                     /translation="MFDSKQNLAKSQWMFIIIIAVMDLVVLVATLLAKTSFQRYLVGG
                     VAVILTSFLILLVWGLKTAKKLQTRLDSKEVLDSKVRDDQKLPKYDERQKQILLKGYT
                     IGFWFMIVVIWLSLFISRFTEGLVSASFLFTLALWGGLAVQTTYCNLNGASSFVDRRF
                     GKQGILMGMIATGMSLVVIGLAVREMMTGPLKMGSFFKAGGSGTLMVLGITLLSMGAS
                     IFYRHYLDAKEADE"
     gene            42828..43034
                     /locus_tag="VB649_000646"
     CDS             42828..43034
                     /locus_tag="VB649_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1669617.1"
                     /translation="MKNLKLKAARAGKDLSQQALVDLVGVSRQTIAAVEKGDYNPTIN
                     LCIAICRVLDKTLDDLFWEADDSR"
     gene            43252..43698
                     /gene="rplM"
                     /locus_tag="VB649_000647"
     CDS             43252..43698
                     /gene="rplM"
                     /locus_tag="VB649_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEP1669618.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            43719..44111
                     /gene="rpsI"
                     /locus_tag="VB649_000648"
     CDS             43719..44111
                     /gene="rpsI"
                     /locus_tag="VB649_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEP1669619.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(44221..45438)
                     /locus_tag="VB649_000649"
     CDS             complement(44221..45438)
                     /locus_tag="VB649_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP1669620.1"
                     /translation="MSIKKTKNGTYQLRVYIPEDTQAKLGLGKLYEKRFKTRREAKEA
                     ELKLSVDIEKARHNKHFQQPLKKEDILFSDFYKEVCLEPYKAGQTTNTNKPPTAATIF
                     QTENLFRLHILPILGKYSLSYLNENKQLVLSLLTPKANSFANFKALRGYINSVFDWAE
                     ELEYIPVNRLHKTISRIKATKKQILKENKREEDLALDEDELRFWLQAFDDDLEKGLLE
                     FKDYVLFYTTFFLSDRKSESYALQWKHINFKNNEILIENALDRFGNVKATKGGKRTLF
                     NAPTELMELLKKWKALQREELKQFGIKQTNNQFVFTYNDRQNNINVVLHIDYLNYRMN
                     SIKRRHSELAPATPHKLRHTGATLAKKAGRSLEEISEALTHSDQSITKTYINTTSTVT
                     QTAGETAYRHLKK"
     gene            complement(45478..45723)
                     /locus_tag="VB649_000650"
     CDS             complement(45478..45723)
                     /locus_tag="VB649_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP1669621.1"
                     /translation="MQVILAEEQTLEIQHMIGELIKSEVKNARESVGADSPFLNKRQA
                     CDYLGISNNTLDLWISMGLPYIKIGKSIRFNKESVNH"
     gene            complement(45907..47019)
                     /locus_tag="VB649_000651"
     CDS             complement(45907..47019)
                     /locus_tag="VB649_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP1669622.1"
                     /translation="MKKLFKLSLLSSLLLPLLLVIVCVAAIADDSSNTSSNGSSTGKR
                     TTLTAKEVAQKASITEERAEDVIKILNYQLSKEGFTLAGSTGSLAVAERESGFDPKAI
                     NTGGGVAGYLQWSGWSNTVNGDRWAQASSRTLDADVELQLMSTELNGAYKKVKTEMQK
                     ATDPGDAALYWSEHYEGVALSDGQTKAEKLQTDADKWFKVFDGTITSDSSVALSGDTG
                     LATGTLTSTFDLPPEYLGKLKYGVPSENSVTTQGNNTYPAGQCTWYVCNRLIETGICT
                     DSAIYNYNGNGQDWVASLVSRGWKQVSEPQVGAVMSVQGGYGGTYAEYGHVAFVEAVN
                     QDGTFLISECNVGGVQNKPHYAVLSNQSYYSFAVAQ"
     gene            complement(47038..47265)
                     /locus_tag="VB649_000652"
     CDS             complement(47038..47265)
                     /locus_tag="VB649_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669623.1"
                     /translation="MNTIRIYTRSQIQPVLEKYIYQAYENDLRAIKVTILYPVNDQEA
                     KRIIELCRAIPAVLDAKWLFGTVIFKVYLKH"
     gene            complement(47252..49162)
                     /locus_tag="VB649_000653"
     CDS             complement(47252..49162)
                     /locus_tag="VB649_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003103538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP1669624.1"
                     /translation="MQEAFEKLKGVDIFALKSYLEKTSIIETSIIVAMNEIFVNLFFF
                     LLNLVVGFFSLMIRIMENIDLYDSYKTYVYNAAKSIWQGLTGSISGGLSSGSLVSMLL
                     TIGAFYLFYQYFFSRGNFMRKVLHVLLVVLLGFGYFGTVASTSGGLYILDTVDNLADT
                     VTSKISNISVSYGEDKSIKVGKSMADSYIAQTSYTAYVFVNTGQENGKYVNSQTGEEE
                     AFDDSKVLGSVDDSGKFVAVKNKDRKDYLDKLGDKADDGKEKNRWVSAVWDYLFIKTF
                     YVIFKIIEAIVIEVPIILVQLLNLIAQLLVLVMIFLFPIALLISFVPAMQDIIFGIFK
                     VMFGSLVFPTITTLITLIIFYIEKVIETLITSGFDGVIESFPSLGTFALLFKLILSVV
                     AKAAVYYFLWIYKGELIEFIMGSRARIKMEDIGNQVEDKVSQGKDLIQQMPSRNFEAA
                     QHLGNFAMAGNGFVAGSAMNASSHIKEVGNFFRRSKPSEPAVEPNVPTDQPTEQPGPT
                     PDQLPPTSSEPHIPKQDIPTDNPTQEKTPTPEATPSQPTTPPSPEMEFQELKEQWVSP
                     RKQRKMERLEREFSAYDDAGAMYQAQGSNAFTRSFSQTMTRDDKIKANIERKNRLTQE
                     LNRLRGEQNEHY"
     gene            complement(49177..51681)
                     /locus_tag="VB649_000654"
                     /pseudo
     CDS             complement(49177..51681)
                     /locus_tag="VB649_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646450.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(51694..52116)
                     /locus_tag="VB649_000655"
     CDS             complement(51694..52116)
                     /locus_tag="VB649_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP1669625.1"
                     /translation="MKNEKEPLYDYARGLNAPYWIQEIKTQKGARIWYFATPMQLSFF
                     VVFILVFVVMLLGLSFILVPLAKITHSISMLLYAYVPYKFAKFYTEYEPHGKKMHIFL
                     ADYFRYLYEFRWNKKAIYHDERVESYDDDDIVFEQTHL"
     gene            complement(52118..52342)
                     /locus_tag="VB649_000656"
     CDS             complement(52118..52342)
                     /locus_tag="VB649_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003005585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669626.1"
                     /translation="MNTSSLQQFLQGDGAWIITAVAILLAIKAWKNSSWLQLFSVIGF
                     WGIIMSMTKGQQILSVISWFLRLFGIETGL"
     gene            complement(52348..53328)
                     /locus_tag="VB649_000657"
     CDS             complement(52348..53328)
                     /locus_tag="VB649_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP1669627.1"
                     /translation="MNKLKTLIQQVTHYLSRFKKQDKKRGSPKLIKTTRKNVNILVLT
                     GLGCLVFVGASGSLRAITLSNKVTSLEKEVKKAQSSQVVTTATNTDYRLTYYLNDFVA
                     TYFSFSDKAEEQEAQIEKLNNFYGVEPEIKSQGQKRTPMSLISARLLLLTDNTATYQV
                     TYKQKVGDKEEEIATGFNIPYASKNGSYYVSGLPWYSSLSDNQAKGFNKESVLSLTAS
                     DNLPEKTHKKVEKFLNVFFTNYTTDQDNLDLVGKDLVVLENTTFKSLDYVYLVEDGES
                     ITAYVQVTFEVAANTRSENFTLTLTPKGNSYYVTKVAHTIPKDYAEHEGE"
     gene            complement(53341..53892)
                     /locus_tag="VB649_000658"
                     /pseudo
     CDS             complement(53341..53892)
                     /locus_tag="VB649_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104355.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(53913..54143)
                     /locus_tag="VB649_000659"
     CDS             complement(53913..54143)
                     /locus_tag="VB649_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002270998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669628.1"
                     /translation="MEYKVELSSIDNFKAWSGARETLDTVRERGGIDQLTSLCEDVFS
                     ESTPTEGQINDWLWFDDDYIYQALGYHDLIEE"
     gene            complement(54207..54629)
                     /locus_tag="VB649_000660"
     CDS             complement(54207..54629)
                     /locus_tag="VB649_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP1669629.1"
                     /translation="MSLVLSLIETWQKSKRVTTSPLKKWRRSYLDRYTVNIPQTIFDQ
                     IKSIKNYIQDVLLSPDAALKTSQLLLEGIKSLQTFPERGFDADEKVGRQISKQYKTFG
                     IVIANHKYLLFYNINTEDKIVYVTHLLPVKSDYAKLFL"
     gene            complement(54535..54816)
                     /locus_tag="VB649_000661"
     CDS             complement(54535..54816)
                     /locus_tag="VB649_000661"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669630.1"
                     /translation="MTVVKTRQIGNSLSITIPKEFEIPQGQEYNVYKGSDGTLIFSPS
                     KENLLEEATDELIREKMIDELGAIIDRNMAEIEAGNYVTIEEMEAELLG"
     gene            complement(54873..56126)
                     /locus_tag="VB649_000662"
     CDS             complement(54873..56126)
                     /locus_tag="VB649_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEP1669631.1"
                     /translation="MDKLSPLNLKKFRKQTGMTQKQFAESVGISTRTYRSYEDGSRGL
                     SLEKFGQFKAELGYHKDSTDDLIDVHIDYLRMTFMSIRDLSHFCQTYLHCSFTEFKEF
                     ETRLLNYTRLWKRGNIWLFDFFDKIETGNYQVTLQLSGQGCREMELVLDSIDMSWQEF
                     LQALLFDLTDSRVTRLDIAMDERYLGHDREDEQFLLSDMIAKVYKDEVSFKNIRTWNH
                     IGGGNLRNLDEVEGSQGISLYFGSRQSNLYFNFYEKRYELAKSEQISVEESLEIFGIW
                     NRYELRFAQEKAQLAIEEYISGVDLAEIARGIINHEMQVYDGTNKFGAFVPDQKWQRM
                     FGGTDPLKLRMKPEPYSIDRTIKWLMYQVVNSLKLVEEADKIMETDFIKMIQENSEIT
                     DRAESILQDLQASYNLKKKEGETIN"
     gene            complement(56347..58026)
                     /locus_tag="VB649_000663"
                     /pseudo
     CDS             complement(56347..58026)
                     /locus_tag="VB649_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149315.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            complement(58042..58497)
                     /locus_tag="VB649_000664"
     CDS             complement(58042..58497)
                     /locus_tag="VB649_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001062570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEP1669632.1"
                     /translation="MAKTGLNFGEKLQIVDKSYRVITDALKLDEVFGKLTFRSIEGAE
                     LIYEADRNQRNEDGSYVQVPTGEIRGITVGIHSANQHETLFFTIVDMSEQQLNDLGLN
                     YREEVELTDIVVTYSAIGRNDNYRLYASAIKKKGAQTAPKSEPKAEDKK"
     gene            complement(58516..58812)
                     /locus_tag="VB649_000665"
     CDS             complement(58516..58812)
                     /locus_tag="VB649_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HEP1669633.1"
                     /translation="MIPETLVMKPEFIGNAYYEKLGNAPRTVFGKEGKYQRHVLNSQE
                     HGAFHVITPATNTVFDEDTLVKVIIPIFFPDRAVNGSNVAPALNVFAEKLEIVK"
     gene            complement(58850..59098)
                     /locus_tag="VB649_000666"
     CDS             complement(58850..59098)
                     /locus_tag="VB649_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669634.1"
                     /translation="MTSYFAKTLERHFQNYCFTHNMYAQHPDLQASLFVSAKDEIDKL
                     ITQFQRVGYPMAELNSYSRLYKSKINRFYFAQVSPVMC"
BASE COUNT        17243 a        11355 c        13360 g        17449 t
ORIGIN      
        1 aggtaactcc agctccagaa aaacctgctg acaaagaagc taaccaaacg ccagaacgcc
       61 gcaatggcaa tatggctaag acacctgtag ccaacaacca cagacgtcta ccagcaactg
      121 gtgagcaagc caacccattc tttacagcag cagcagtagc agtgatgaca acagctggtg
      181 tcctagccgt tacaaaacgc aaagaaaaca actaatcctc tgaattgaga gaccttactg
      241 ataagcaaac ataatggaga gagccccttg gttctctcta tttttggtcg ggagcaggcc
      301 gttggtatca tgctcacgcc tgagagatcc caaaagatat caaaagcagc tcactaaccg
      361 ttttctaaga aaaggtcaca ctaagcgctt tcttagcaga ttctgccttt tgcttttgtg
      421 tgtaaagtgt taaaataggg aaaagaaatg ctagatgagg aacgaaatgg caaaaataat
      481 gaacgtaaca ggagaagaag tcattgcctt agcggccacc tatatgacca aggctgatgt
      541 ggcttttgtg gcaaaggctt tagcatatgc aacagcggcc catttctacc aagtgagaaa
      601 gtcaggcgag ccctatatcg tccatccgat tcaggtggcg gggattctgg ctgatttgca
      661 tctggatgct gtgacagttg cctgtggctt tttacatgat gtcgtagaag atacggatat
      721 taccttagat gagatcgaag cagactttgg ccaagatgct cgtgatatcg ttgatggtgt
      781 caccaagtta ggtaaagttg agtacaaatc tcatgaggag caactcgccg aaaaccatcg
      841 caaaatgctg atggctatgt ccaaagatat tcgcgtgatt ttggtgaaat tggctgaccg
      901 cctgcataat atgcgcaccc tcaaacattt gcgcaaggac aaacaagagc gcatttcgcg
      961 cgaaaccatg gaaatctatg cccccttggc gcatcgtttg gggattagtc gcatcaaatg
     1021 ggaactagaa gatttggctt ttcgttacct caatgaaacc gaattttaca aaatttccca
     1081 tatgatgaaa gaaaaacgtc gcgagcgtga agctttggta gaggctattg tcagtaaggt
     1141 caaaacctat acgacacaac aagggttgtt tggagatgtg tatggccgac caaaacacat
     1201 ttattcgatt tatcggaaaa tgcgggacaa aaagaaacgt ttcgatcaga tttttgatct
     1261 gattgccatt cgttgtgtca tggaaacgca aagcgatgtc tatgctatgg ttggctatat
     1321 tcatgagctt tggcgtccca tgccaggccg cttcaaggat tatattgcag ctcctaaagc
     1381 taatggctac cagtcgattc ataccactgt gtatgggcca aaaggaccta ttgagattca
     1441 aatcagaact aaggacatgc atcaagtggc tgagtacggg gttgctgctc actgggctta
     1501 taaaaaaggc gtgcgtggta aggtcaatca agctgagcaa gccgttggca tgaactggat
     1561 caaagagctg gtagaattgc aagatgcctc aaatggcgat gcagtggact ttgtggattc
     1621 ggtcaaagaa gacatttttt ctgagcggat ttatgtcttt acaccgacag gggccgttca
     1681 ggagttgcca aaagaatcag gtcctattga ttttgcttat gcgatccata cgcagatcgg
     1741 tgaaaaagca acaggtgcca aagtcaatgg gcgtatggtt cctctcactg ccaagttaaa
     1801 aacaggagat gtggttgaaa tcatcaccaa tgccaattcc tttggcccta gtcgagactg
     1861 ggtaaaactg gtcaaaacca ataaggctcg caacaaaatt cgtcagttct ttaaaaatca
     1921 agacaaggaa ttgtcagtga ataaaggccg tgatttgttg gtgtcttatt ttcaagagca
     1981 gggctacgtt gccaataaat accttgacaa aaaacgcatt gaagccatcc ttccaaaagt
     2041 cagtgtgaag agtgaagaat cgctctatgc agccgttggg tttggtgaca ttagtcctat
     2101 cagtgtcttt aacaagttaa ccgaaaaaga gcgccgtgaa gaagaaaggg ccaaggctaa
     2161 agcagaagca gaagaattgg ttaagggcgg tgaggtcaaa cacgaaaaca aagatgtgct
     2221 caaggttcgc agtgaaaatg gagtcattat ccaaggagca tcaggcctct tgatgcggat
     2281 tgccaagtgt tgtaatcctg tacctggtga tcctattgac ggctacatta ccaaagggcg
     2341 tggcattgcg attcacagat cggactgtca taacattaag agtcaagatg gctaccaaga
     2401 acgcttgatt gaggtcgagt gggatttgga caattcgagt aaagattatc aggctgaaat
     2461 tgatatctat gggctcaatc gcagtggtct gcttaatgat gtgctccaaa ttttatcaaa
     2521 ctcaaccaag agtatatcga cagtcaatgc tcagccgacc aaagacatga agtttgctaa
     2581 tattcacgtg agctttggca ttccaaatct gacgcatctg accactgttg tcgaaaaaat
     2641 caaggcagtt tcagatgttt atagcgtgaa gcggaccaat ggctaagaaa ggataaaacc
     2701 atgaaacttg tcttgcaacg ggtcaaagag gcctctgttt ctattgatgg gaaaattgct
     2761 ggcgctatta atcaagggtt gttgttgtta gtaggtgtgg gaccagatga tactgcagaa
     2821 gatttggctt acgctgtgcg aaaaatagtc aacatgcgca ttttttcaga tgctgatggc
     2881 aagatgaatc agtctatcca agacatcaag ggcagtatct tatctgtgtc gcaatttacc
     2941 ctttatgctg acaccaaaaa gggaaaccgt cctgccttta ctggtgctgc taagccagat
     3001 ttggctaggc agttgtatga cagctttaat gaacaattgg cagagtttgt gccagttgag
     3061 cgtggcgttt ttggggcaga tatgcaggtt agtctcatca atgatggacc agttacgatt
     3121 attttagaca cgaaatgtca ctagtctcta caactaagag gttagaaaaa gcaagcaact
     3181 gttgatagcg tgttgcttgc tttttttgtc agttaatctc atcgttttag aagatcgagg
     3241 ttatttgtcg ttagggttat caggtatagg tgtccctgta taacgcaggt agctgtaaac
     3301 ttctcgttct tcttcggtat aacgatcttt atcataagct aaatgatagc tagcattctc
     3361 tccttcgggt cgcttgccca tataaacggt tatgatacgg ttggtgtcat cgtgattatc
     3421 ctctacgttt ccagttaagg tatagtccat aataccaaaa gcatcgagat tgttgtagag
     3481 tagtttagcc ttatcacgag gatcgtataa atctctgaag tctaagttac gttcgctagc
     3541 tgttaagagc tgctcgcttt ttagcaattt gttggtatcg acatcaacgt aattgatggt
     3601 gaacagtttc aagtgactgc gatcaaaggg atcatacggt tcctcccctt ttttaaggac
     3661 gtaatatttc tcagagatca ggtcagtgtt gtttattttt tctttctgac cagatttttt
     3721 attgatccca taagcttgtt cccgattttt gacacggtaa gtaaactctt gatccattgg
     3781 taaaatcgta cggaaaatgt cattgtcatg tgtgacgatt gaggagtcac gttttgtaat
     3841 gatataatct ggatgctctt ttgataggat aaattgggca attgctgcta actcttgtga
     3901 tgaaagagag tcaccaactg ccagtgtggt caaatggtat cgatctctta acgatggcgt
     3961 aaagtctaaa tctcctgttt cggagacaaa gctcacttca tagttgacgt taacgcgttc
     4021 agcagagttg tgaacggttt taggttgata cggtctaacg cgcacatgcc cgcttagcaa
     4081 aaattcttgg acaggttggg tcggcaaggt taccgaatca tctcggtcag caaagtagac
     4141 cttgccgttt cgatcagtaa tagttgcatc gcttgcaaaa tcaatgacct caaagtagcc
     4201 gtcgttactg tgaacgtcag cgatcaattg ttcttgaata gcctttaata agtcagcttt
     4261 ttcaagttta tgtgacattg cgcctttatc tgtagcaaat ggttttgatt ttggatttaa
     4321 gccttgctct gtctttcctc cctgagcagg tcgtgatgtt aggtcaattt caaaaaattt
     4381 aaggctaatt tcttgattcg tcccctcaac agtaccagca acgctaacaa ctaattggct
     4441 gttgttgaca gatggacggt ctagcagcca ttcaggtcca gcaatagctt ggacaggctt
     4501 gactgttcca aatgttaatg caaacagcag tgcaaacatc ccaaaagata agtaattttt
     4561 catagaaacc tcctaaaagt taagtttcaa tccccattat tagaataaca taataatttt
     4621 atagatacaa acaaaaacct aataattgtt tttaaatgat atcttaatga taatgtcgtg
     4681 ataatgaaaa aagagaaata atacctgttt tagtataaac ataaattaat cttccgataa
     4741 atagctattt gatggaatgt tcttgctaaa aatgaataac tattatttag ctttaatgat
     4801 taaaaaggca gaaaatacaa aatcatgctg acaacaaacc gaactgtgtg ataaagagtc
     4861 atgtgttata atggtttaaa gaccgtcatg aaaggaatgg ctatggagct aaaagactat
     4921 tttccagaga tgcaagtagg ccctcatccg ttaggagata aagagtgggt gagtgtcaaa
     4981 gaaggggacc aatatgtgca ttttcccaaa tcatgtttgt ccgaaaaaga gcgcttatta
     5041 cttgaggtgg gactgggtca gtgtgaggtc ttgcagccgc tagggtcacc ttggcagcgg
     5101 tatttgcttg atcatcaggg caatccccct cagctgtttg agacttctca gttcatttac
     5161 cttaatcatc agcaggcttt accagctgac ttagttgagt tgctccaaca gatgattgca
     5221 gggcttgagg tcattttgcc tatcagtgca acccaaacgg catttttatg ccgacaagca
     5281 atctcaataa aggtcttgcg ctggcttgaa gatctcttgc caacgctaga aagtgatttt
     5341 ggtttggcct taaccatgtt tgttggaaat gcctggtatc aagtagctgc gggtacattg
     5401 agagagtgtt ttgaggagga atgtcagctg ttaacggcct atttaaggca acaatcaggc
     5461 agaaaattat taacattttc aggactgatg ctgtggtctt tgctgtcgca ccacactttt
     5521 ttggcattga cgcgtcagtt tcaccaattc ctaagtcctc aaagtgatat ggccgatgtg
     5581 gttcacgcgc tatggtcaga acacggcaat ctggtgcaga cagcgcagcg cttgtatatt
     5641 caccgtaact ccttgcaata caaacttgat aaatttgctc agcaatcagg actacacttg
     5701 aagcaattgg atgatttagc ctttgctcat ctctttttgt tgaaatatta ggaaagccac
     5761 agggctttct tttttgctgc cttgactgta gctgataagg agaatgatag atcgttcagc
     5821 ttgttttggc tcctgtgacc ggcctgtgtt tacatggttt tcttgtttta tggtccccta
     5881 cgacttgact agccctgcta ttgtgcaagt tgcccaaaga agtttggtcg ctttgtctct
     5941 gttttgaaag cgctattttt gttataataa aagcatcata taaaagatat cagcggtttc
     6001 tagctttgca gtcagctaga acgtttgctg gctaaatagg agttatacat ggttgaatta
     6061 aatctaaatc acatctataa aaaataccca aatactactc attatgccgt tgaagatttt
     6121 gacttagaca ttaaagacaa agaatttatc gtctttgttg gaccttcagg atgtggtaaa
     6181 tcgactactc ttcgtatgat tgcaggtctt gaggacattt ctgaaggaga gttaaaaatc
     6241 ggtggcgaag tggtgaatga caagtcgcct aaagaccgtg atattgccat ggtctttcaa
     6301 aactacgccc tttacccaca catgaccgtg tatgataaca tggcctttgg tttgaaatta
     6361 cgtaagtaca aaaaagatga tattgaccgt cgtgtcaagg aagctgcgca gatccttggt
     6421 ttgaccgaat ttctagagcg taaaccggct gacctgtctg gtggacaacg ccaacgcgtt
     6481 gccatggggc gtgctattgt ccgtgatgct aaagtgttct tgatggatga gcctttgtca
     6541 aacttggatg cgaagcttcg tgtctccatg cgtgctgaaa tcgcaaagat tcaccgtagg
     6601 attggctcaa caactattta cgttacccat gaccaaactg aagccatgac tttggcagac
     6661 cgtatcgtta tcatgagtgc tactaaaaac cctcaaggta atggaacgat tggtaaaatt
     6721 gagcaagtgg gttcaccaca agaattgtac aaccttccag ctaataaatt cgttgccggc
     6781 tttatcggaa gccctgccat gaacttcttt gaagtggaag ttaaagatgg ccgcattgtg
     6841 agtgaagatg gtcttgctat tgcgattcct gaaggacaag caaaaatgct tgaagcggct
     6901 ggttacaagg ggaaaaaagt cacttttggt attcgtccag aagacatttc tagtagacaa
     6961 atcgtgcatg atacttatcc aagtgcaact gtcacagcag aagttttggt ttctgagtta
     7021 ctgggatctg agacgatgct ctatgtcaag cttggacaaa ctgagtttgc ttctcgtgta
     7081 gatgcgcgtg atttccatag tccaggggag caagttagct tgacctttaa tgtggctaag
     7141 gggcatttct ttgacagaga taccgaacaa gctattcgtt aaggtataag cgatattcat
     7201 aaaaaggttg ggttccagcc tttttatcat gtcatttgcg caaacgattg cacaaaaaga
     7261 gaaaaaacgt taaaataaaa gatgaatgaa tgattaatag gagaagaata atgaagaaac
     7321 actggtggca taaagctacg atttatcaga tttacccgag atcctttaaa gacactagcg
     7381 gcaatggtat tggtgattta aaaggcatta ccagtcaact ggactacttg caaaaacttg
     7441 gcattacagc catttggtta tctcctgttt accaaagtcc aatggatgac aatggttatg
     7501 acatctctga ctatgaagcg attgctgaag tttttggaga catggcagat atggatgagc
     7561 tcttagcagc agctaatgag cgaggcatta agattatcat ggacttggtg gtcaaccata
     7621 cgtctgatga gcacgcttgg tttgttgaag ctagagaaaa tcccaatagt cctgagcgtg
     7681 atttttatat ttggcgagat gaacctaacg atttgacttc tatttttagt ggctcagctt
     7741 gggaatatga taatgcatca ggtcaatatt atttgcacct ttttagcaaa cgtcagccag
     7801 atctcaactg ggagaatgaa gctttacgtc ataaaattta cgatatgatg aatttctgga
     7861 ttgccaaggg catcggtggt tttcgtatgg acgtaattga cctgattggg aaggttcctg
     7921 acttggaaat cacaggtaac gggccgcgct tacacgatta cctcaaagaa atgaatcaag
     7981 caacctttgg caaccatgac gtgatgactg tcggtgagac ttggggagca acgcctgaaa
     8041 ttgctcgcca gtattctcgc cctgaaaaca aagagttatc catggtcttc caatttgagc
     8101 atgtgggtct tcaacataaa cctgacgctc ccaagtggga ttatgccaaa gaattagacg
     8161 tgcctgctct gaaagctatt ttcagcaagt ggcagacaga attaaagttg ggagaaggct
     8221 ggaattcgct tttttggaat aaccatgact tgccacgggt cttatccatt tggggcaatg
     8281 acagcactta ccgagaaaaa tcagccaagg ctttagctat tttactgcat ttgatgcgag
     8341 gaacccctta catttaccaa ggagaagaga ttggcatgac caattatcct tttaaagact
     8401 taaccgaggt taatgatatt gagtccctta actatgctaa ggaagctatg ggaaatggag
     8461 tgtcagctgc gcgtgtgatg gatagcatcc gtaaggtagg acgagacaat gctagaacgc
     8521 cgatgcagtg gtctaaggac acacatgctg gcttttctaa agcccaagag acttggttgc
     8581 cggtcaaccc caactaccaa gacatcaatg tggccgatgc ccttgctgat ccagactcta
     8641 ttttttacac ctaccaaaaa ttgattgcct tgcgtaagga gcaggactgg ctagttgaag
     8701 cggattatca cctcttgcca acagctgata aagtgtttgc ttatcagcgt cagcttggag
     8761 aagagacgta tgtgattgtt gtcaatgtgt ctgatgagga gcaagtcttt gccaaagact
     8821 taacaggtgc acaagtgatc atcaccaata cagatgtgga cacggtgttc gagaccaagc
     8881 acttacaacc ttgggatgcc ttttgtctca aactgaaggc ctagcagttg tatgtgattt
     8941 gagtttaccc aacagccaag cgagtggaaa ctcgttttgg ctgtttgatt tttgagatcc
     9001 tattaagggg tgatagtcat tgtttgagct gtgttctaag ttgaagtgcg gcatgtcttg
     9061 caagcgcttg cgcaatgtga taagatagtc ttgtttgaat gttatattaa atggaggtct
     9121 tatgaaaaag aaagtcaacc aaggatcaaa gcgctatcaa tatctgttaa aaaagtgggg
     9181 gataggtttt gtaatcgctg caactgggac tgtcgtgtta gggtgcatcc ctagtatctt
     9241 aacacatcaa gttgctgcta aaaccattgt tggactagcc cgcgatgaag ctcaacaagg
     9301 agatggcaat gctaaatctg gtgatggttt tcaatcgtct agcaaggagg ctaaaccagt
     9361 tttagacagc tcgtcagcta atcctgctag tattgctgag catcatttgc gtatgcattt
     9421 taaaacattg ccagctggtg agtcgctagg aagcttggga ctttgggtgt ggggagatgt
     9481 ggatcaacct tcaaaggatt ggccaaatgg tgctatcacc atgacaaaag cgaaaaaaga
     9541 tgactatggc tattatctag atgtgccact agcagctaaa caccgccagc aagtgtctta
     9601 tctcattaat aataaagctg gagagaatct ttcaaaggac cagcacatct cgcttctcac
     9661 gccaaaaatg aatgaagttt ggatagacga gaattaccat gcgcacgctt atcgaccttt
     9721 gaaaaaaggt taccttcgaa tcaactacca caatcaatcg ggacactacg ataacttagc
     9781 tgtctggacc tttaaagatg tcaaaacccc aacgaccgac tggccaaatg gacttgactt
     9841 gtcacataaa gggccttacg gagcttatgt tgatgtcccc ttaaaagaag gagctaacga
     9901 aatcggattt ttaatccttg ataaaagtaa gacaggagat gctattaaag tgcaaccaaa
     9961 agattatctg tttaaagagt tagacaatca tactcaggtt tttgtcaaag acactgaccc
    10021 aaaagtttac aacaatcctt attatattga tcaggttagt ctcaaaggag ctgaacaaac
    10081 cacgccaaat gagattaaag ccatttttac gaccttagat gggcttgatg aagatgcggt
    10141 gaaacaaaac atcaagatca ctgacaaagc agggaaaact gttgcaattg atgagttgac
    10201 acttgacaag gataagtctg taatgacatt aaagggtgat tttaaggcac aaggtgcagt
    10261 ctacacggtt acatttggag aagttagcca agtcgctcgc caatcctggc aattaaaaga
    10321 taaactctat acttatgatg gtgaacttgg agctacccta gctaaggatg gttctgttga
    10381 tttagcacta tggtctccga gtgctgatac tgttaaggtt gtcgtttatg ataaacaaga
    10441 tcagacaagg gtggttggtc aagctgattt gaccaagtcg gacaagggtg tttggagagc
    10501 tcatctgact tctgacagtg tcaagggcat tagtgattac acaggctact attaccttta
    10561 tgagatcacg cgcggtcagg aaaaagtcat ggttttggat ccttacgcca aatctctcgc
    10621 tgcctggaat gatgcgactg ctactgatga catcaaaaca gcaaaagctg cctttattga
    10681 tccaagcaaa ctaggaccaa caggccttga ttttgccaaa attaacaact ttaaaaaacg
    10741 tgaagacgct attatctatg aagcacatgt gcgagatttt acgtcagata aggctctaga
    10801 aggtaagtta acacaccctt ttgggacttt ttcagctttt gttgaacagc tagactatct
    10861 caaagacttg ggggttaccc acgttcaatt gctaccggtt ttgagttatt tttatgccaa
    10921 tgagctggac aagagccgct caacagccta cacgtcttca gacaataatt acaactgggg
    10981 ttatgaccca caacactact ttgccctttc tggcatgtat tcggcaaatc ctaatgatcc
    11041 tgctttacgt atcgcagagc ttaaaaacct tgtcaatgag attcacaaac gtggtatggg
    11101 tgttattttt gatgtggttt ataaccacac ggctagaacc tatctctttg aagatttgga
    11161 acccaactac tatcatttta tgaatgctga tggtacagct agagagagtt ttggtggagg
    11221 tcgtctagga acgacacatg ccatgagtcg tcgtatcttg gtggattcga ttacttacct
    11281 gacgcgtgaa ttcaaggtag atggttttcg tttcgacatg atgggtgacc atgatgcggc
    11341 agctattgag caagccttta aggcagccaa agccattaat ccaaatacca ttatgattgg
    11401 cgaaggctgg cgtacctacc aaggtgatga ggggaaaaaa gaaattgcgg cagatcaaga
    11461 ttggatgaaa gcaaccaata cggtcggtgt tttctctgat gatatcagaa ataccctcaa
    11521 gtcaggtttc ccaaatgaag gcacagcagc ctttattact ggtggcgcaa aaaatctaga
    11581 aggactgttc aaaacgatca aagcacagcc tagtaacttt gaagcagatg ccccaggaga
    11641 tgtagtgcag tatattgcag cccatgacaa cctgacctta catgatgtca ttgccaaatc
    11701 catcaataag gatcctaaag tggctgaaga agagattcac aagcgtattc gtctaggaaa
    11761 taccatgatt ttaactgctc aagggactgc ctttatccat tctggtcagg aatatggacg
    11821 aaccaagcag cttctaaatc ccgactacaa gacaaaggtg tctgatgaca aggtgccaaa
    11881 taaggcgact ctgattgatg ctgtagcgca atacccttac ttcatccacg attcttatga
    11941 ttcgtctgat gcggtcaatc attttgactg ggcaaaggca acagattcca tagctcaccc
    12001 gattagcaac caaacaaaag cctatacaca gggactaatt gcgttgcgtc gctcaacaga
    12061 tgcctttaca aaagcaacca aagctgaggt agatcgggat gtgaccttga tcacccaagc
    12121 aggacaagat agtattcaac aagaggacct tatcatgggt taccaaacgg tggcatcaaa
    12181 tggagatcgc tatgctgtct ttgtcaatgc agacaacaag acccgcaagg tagttttacc
    12241 tcaagcctac cgctatttgc taggagccca agtgcttgct gatactgagc aagctggtgt
    12301 tactgccatt gctaagccta agggagtcca gtttaccaaa gaaggcttga ccattgatgg
    12361 cctaactgcc ctggtcctca aagtatcctc aaaaacggct aatccctctc agcaaaagag
    12421 tcagacagac aatcatcaaa ccaaaacacc agatggctca aaagacctag acaaatcatt
    12481 aatgactagg ccaaaaagag ctaaaacaaa ccaaaagctc ccaaaaacgg gtgaagcctc
    12541 ctcaaaaggc ttattagcag ctggagtagc tctgctttta ttggctatta gcctgttgat
    12601 gaagcgccaa aaagattagg gtggtgttaa taatagcact tgaatgaatt tcaggtgcta
    12661 tttgctattg cctgctctaa gtttctttca aaagcatcga gcgaatttct ttttgtcata
    12721 gacaaaacca ggattggtct aaaatcctta aaaaaagaac tttaataatt aaggatacag
    12781 tattataata aaactatata aacataaaat gaaaataaat tttatgatag tataacgaca
    12841 aaaagaaaga gagagcttcc tttatgaaac aaaaaaatat taataaactt gtgtgtcgct
    12901 atggcttaac cactgcagcg gctattttgg cgaccttcgg gggggtagcg aacgtcaggg
    12961 ctaatgctga aagcatgcag tatgtaggta aagatctcga aaagactctg gagaaagatt
    13021 atgagaacta tgttcctaag atcaataact ctcgagaagg gagagatcct agtaaaccag
    13081 ttaatattga agactatttg gctaggattc aagagtactt agaagctcga aaaagagatg
    13141 attacgaatg gaaagataaa ataactaaaa gtatacaaaa tggcaccttc caaggtgaca
    13201 agggagatat gggaccagaa gggaagccag gacctaaggg ggacaaaggt gaaaccggtg
    13261 gtcagggtcc aagaggagaa cgtggcgaaa ctggccttca aggagcacca ggtgaacgcg
    13321 gtgagcaagg cccagcaggt cctaaaggtg acaagggtga gcgcggtgaa aaaggcgaaa
    13381 ccggagcaac tggcgcacaa ggcccacaag gtgaagctgg taaagatgga gcaccaggcg
    13441 aaaagggtga aaaaggtgaa actggcgcac aaggcccagc aggtcctaaa ggtgacaagg
    13501 gtgagcgcgg tgaaaaaggc gaaaccggag caactggcgc acaaggccca caaggtgaag
    13561 caggtaagcc aggcgaaaaa gctccagaaa agagcaaaga ggtaactcca gctccagaaa
    13621 aacctgctga caaagaagct aaccaaacgc cagaacgccg caatggcaat atggctaaga
    13681 cacctgtagc taacaaccac agacgtctac cagcaactgg tgagcaaacc aacccattct
    13741 ttacagcagc agcagtagca gtaatgacaa cagctggtgt cctagccgtt acaaaacgca
    13801 aagaaaacaa gtaatcctct gaattgagag accttactga taagcaaaca taatagagag
    13861 agccccttgg ttctctctat ttgtttattt ggtgagactg gatcaatgag aaaagctaaa
    13921 taaccccatc ttttggtaat aaaagctctg agctgtgaaa agaccttgtg attgagaaaa
    13981 ttgctacttt agtgtatcat aagaccaaaa gagaaggaga catccatgac atttgaagaa
    14041 atcgttgcga attttatacc gtcgagtgtt gcagaagtca catcagctat tgctagtggc
    14101 aaagatatga ttgtcttttt aggacgttcg agctgtcctt attgtcgccg ctttgctccc
    14161 aagttggcac aagtagcaac agataatcaa aaagaagtct attttgtgga tagcgaaaac
    14221 gctgctgatg ctgctgagct tgctgccttt cgtgagaact accaattagt gacagttcca
    14281 gctttgctgg ttagttacga tcagcaccaa agggctgtat gtgattcaag tttgacacca
    14341 gatgacatct tagctttttt gactcgtgag taaagcactg cgcttagcgt ctcgtttaaa
    14401 gaagacatca ggtaacgtct agtcttgcta taccgcttga tttttgatat agtaagacat
    14461 gacttttata gaataaaaag gagacattat gggatttcca acaattttaa tgtttgtagt
    14521 gatgcttgga ttgatttggt ttatgcaacg tcaacaaaaa aaacaagcgc aagaacgcca
    14581 aaatcagtta aacgctattg aaaaaggaga cgaagtcgta acgattggtg gcatgtttgc
    14641 gattgttgac gaagtcgata caacagctaa aaagattgtg ttagatgtgg atggcgtctt
    14701 tttgacattt gagctatcag ctattaagcg tattgtaaca aaagctacta cagaaacgac
    14761 actggttgaa acagaagaaa ccattgttgt taatgagcct gctgttgaga cggtagatag
    14821 cactgacact gacagtgcca ttgaaagcca ttaaggcggg gaaagtttgg atgaaatatg
    14881 ccaaactttt ttgttttgat ccctggactg agacagttat tctgatgcta acaggttcat
    14941 gaaaagctga cacatctatc aaaggatagg tgaacatttt gtgaagataa gatctaattg
    15001 ataaaaaaca agccaaaagg cgtgaaatat gataaaatat gagataagta tgcttatcaa
    15061 taaggaaaaa acatgtttgg attaaaagcg aaatcaacaa aaaaagtttt gggaagtatc
    15121 ccaaagcata ttggaattat catggatggt aatggacgtt gggccaaaaa aagactaaaa
    15181 cctagagtgt ttgggcataa agctgggatg gatgctttac aagaagtaac gattactgca
    15241 tctgagttgg gggttaaagt tctgacagtc tatgcctttt cgacagaaaa ctggtccaga
    15301 ccccaagatg aggtgtcttt tatcatgaat ttaccagtaa ccttctttga caaatatgtg
    15361 cctgtgcttc atgagaacaa tgtaaagatt caaatgattg gagagactag tcgtttacct
    15421 gaagatacct tggcagcgct aaatgcagcc atcgacaaaa caaaacgtaa tacgggttta
    15481 attttgaatt ttgctctcaa ttatggagga cgtgctgaga ttaccagtgc tgttcgcttt
    15541 attgctcaag atgtcttaga tgccaaatta aatccaggag atattacgga ggatttgatt
    15601 gctaattact tgatgacaga ccatctgcca tatctctacc gagaccccga tttgattatt
    15661 cgcaccagtg gtgagctgcg tttgagcaat ttcttgcctt ggcaatcagc ttacagtgaa
    15721 ttttatttca caccagtctt gtggcctgat tttaaaaagg cagagctact aaaggccatt
    15781 gcggattata accgccgcca acgtcgtttt ggcaaggtct aaaaggagat agttatgaaa
    15841 gaacgtgttg tttggggggg agtagcagta gctattttcc taccttttct cataatagga
    15901 aacctaccat tccaattatt tgtaggcgtt ttggccatga ttggggtatc agaattactg
    15961 aaaatgaaaa gattagaagt cttttctttt gaaggtgttt ttgccatgtt agccgccttt
    16021 gtattggcag ttccgatgga ccattacctc acttttttac caattgatgc gaatgttgct
    16081 ttttacagct taatggtttt tttcattttg gcaggtactg ttttaaatag cagagcttat
    16141 tcatttgatg atgcggcctt tccgattgca actagttttt atgttgggat tggttttcaa
    16201 catttgatca atgctcgcct gtcaggaatt gacaaggtct ttttggcctt atttatcgtt
    16261 tgggccactg atattggagc atatctgatt gggcgtcagt ttggcagacg caaactattg
    16321 cctacagttt ctccaaacaa aaccattgaa ggtagtttag gagggatcgc ttgtgcagtc
    16381 cttgtgtctt ttatctttat ggtgattgat aggtctgttt atgcgccaca tcactttttg
    16441 accatgttgg ttttggtcgc tcttttttcc atttttgccc aatttggtga tttggttgaa
    16501 agtgctctca aacgtcactt tggtgtcaaa gattcaggta agcttatccc gggacatggt
    16561 ggtattttag accgctttga ttccatgatt tttgtttttc ccatcatgca tctctttggt
    16621 ttattttaat cttaagaggt aatgtttgga gtcgcaacaa cgcgacaaaa ctcaaaaaag
    16681 caatagactg aaaggaaatc tatgttagga ataataacct ttattattat ttttggtatt
    16741 ttagtgattg tccatgaatt tggacatttc tattttgcta aaaaatcagg cattctagta
    16801 agagaatttg ccattggaat gggccctaaa attttttctc atgttgacca aggaggaact
    16861 ctttatacct tgaggatgtt acccttgggc ggttatgtgc gaatggctgg ttggggtgat
    16921 gacaaaactg agatcaaaac aggtactcca gcaagtttaa cccttaatga gcaaggtttt
    16981 gttaagcgca tcaacttgtc tcaaagtaag ttagacccaa cgagtctccc aatgcatgtt
    17041 acaggctatg acttagaaga tcagctgagt attactggct tggttttaga agaaaccaag
    17101 acatataagg tcgctcacga tgctactatt gttgaagaag acggtactga gataagaatt
    17161 gctccgcttg atgttcaata tcaaaatgct agtattggcg gacgtttaat caccaatttt
    17221 gcaggtccca tgaataattt tattttaggg attgtggttt ttatcctctt ggtcttttta
    17281 caaggtggga tgccagattt tagtagcaat catgtccgtg ttcaagaaaa tggagcagca
    17341 gctaaggctg gtcttcgaga taatgaccaa attgtcgcaa ttaatggtta taaggtgact
    17401 agctggaatg atctcactga ggctgtagac cttgcaacac gggatctagg cccgtcacag
    17461 accattaagg tcacctacaa gtcacatcag cgcttaaaaa cggtggctgt gaaaccacaa
    17521 aagcatgcaa agacatacac gataggagtt aaggcgagtc tgaaaacagg atttaaggat
    17581 aagctcttag gcggtctaga attagcttgg agtggggcgt ttactatttt gaatgctttg
    17641 aaaggattga tcactggctt tagtctcaat aaattaggtg gacctgttgc catgtatgac
    17701 atgtccaatc aggctgctca aaacggctta gagtcagtct tatctcttat ggcaatgctt
    17761 tcgatcaatt tagggatctt taacctgatt ccgattcctg cacttgatgg gggaaaaatc
    17821 ttgatgaata tcattgaagc cattcgtcgc aagcctatca agcaagaaac agaggcctat
    17881 atcaccctag ctggggttgc tatcatggtc gtattgatga ttgctgtgac atggaatgat
    17941 atcatgcgcg tctttttcta atcaagatag gtcatcttaa gctgacctta tcatgttaaa
    18001 gatcgaaaaa gacctcaacc ctaagatttg caagggttga ggtcttactc aaaatgaaag
    18061 gaatacacat tcaaattatt gaataatccc gcttcactct tacttgatgt ttccagaagg
    18121 gtttgaggat aaggggatgt attaaaacgg aataatctat gaaacaaagt aaactgctta
    18181 tcccaacctt gcgcgaaatg ccaagtgatg cccaggttat cagccacgcg cttatggtgc
    18241 gtgccggtta tgtgcgccaa gtttctgctg gtatctatgc ttatttacca ctggcaaatc
    18301 gtaccattga gaaattcaag accatcatgc gtgaagagtt tgaaaagatc ggtgctgttg
    18361 aaatgttggc accagctctt ttgacagctg atctctggcg tgaatcaggc cgttatgaga
    18421 cctatggaga ggacctctat aagcttaaaa accgtgataa ctcagacttt atcttgggtc
    18481 cgacccacga agaaaccttt acgactttgg tgcgtgatgc ggtcaaatct tacaagcaat
    18541 tgcccttaaa cctttatcaa attcagtcta agtatcgtga tgaaaaacgt ccgcgtaatg
    18601 gcttgcttcg tacccgtgag tttatcatga aagacggcta tagttttcat cacaactatg
    18661 aagatttaga tgtgacctac gaagattatc gtcaagctta cgaagctatt tttaccagag
    18721 ctggtctaga tttcaaaggg attattggag atggcggtgc catggggggg aaagattccc
    18781 aagaatttat ggccattaca ccagctcgta cggaccttga tcgctgggtg gttcttgaca
    18841 agtctattgc gtcaatggat gatattccaa aagaggtctt agaagagatt aaggcagaat
    18901 tggctgcttg gatgatttca ggtgaagata ctatcgctta ctctagtgaa tcaagctacg
    18961 ctgccaacct tgagatggca actaacgaat acaaaccttc ctcaaaagta gctgctgaag
    19021 atgccttgac agaagttgag acaccacatt gcaaaacgat tgatgaagtg gctgcttttc
    19081 tttcagtaga tgaaacacaa accatcaaaa ccttgctttt tgtggcagat aatgaacctg
    19141 ttgttgcttt gctagttgga aatgaccata tcaataccgt taaattaaaa aactatctag
    19201 ctgctgattt tttagagcca gctagtgaag aagaagcccg tgctttcttt ggtgcaggtt
    19261 ttggctcact tgggcctgtc aacttggcac aaggtagtcg cattgtggct gaccgcaaag
    19321 tgcaaaacct tacaaatgcc gttgcaggag ctaacaagga tggtttccat gtgacaggag
    19381 tcaatccagg acgtgacttc caggctgaat atgtagatat tcgtgaagtc aaagaagggg
    19441 aaatgtctcc ggatggtcat ggtgttctcc agtttgcgcg tggtatcgaa gtcggtcata
    19501 tcttcaagtt gggcactcgt tattcagaca gcatgggagc aacgattctt gatgaaaatg
    19561 gcagaacagt tccaattgtg atgggttgtt atggtatcgg ggttagccgc attttgtctg
    19621 ctgtcattga acagcatgcc cgtctctttg tgaacaagac accaaaaggc gattaccgtt
    19681 atgcttgggg tattaacttc cctaaagaat tagccccatt tgacgtgcat ttgattacag
    19741 ttaatgttaa agatcaagtg gcccaagact tgacggcgaa gttagaagct gacttgatgg
    19801 ctaaagggta tgatgtcttg acagatgacc gtaatgaacg cgtcggttcg aaattctctg
    19861 atagcgattt gattggtttg ccaattcgtg tgactgttgg taaaaaagcc gctgaaggta
    19921 tcgtggaaat taaaatcaag gcaacaggtg acagcattga agttaatgca gaaaacctca
    19981 tcgaaaccct tgaaatttta acaaaagaac actaaaaaag aaatgaagag gctgcctgtt
    20041 tagagtggcc tctttttgct gtgaacttgt ctgatacaga gtggcttttg ctttaccaaa
    20101 agcgcttggc gataaaagat tgacaaaaaa atgacctcaa ctgagctatc acttggaata
    20161 aattagccaa agaacgtcag aagaaagccc tgcttttctt tccatctaaa actcgaaaat
    20221 catcttgaat tgtgataaaa taaagcctag taaaatcagg agaaaattat gtcagattta
    20281 ttcgctaaat tgatggacca gatagaaatg ccacttgaca tgagacgttc aagtgccttt
    20341 tcatctgctg atattatcga ggtaaaggta cattcggtgt cacgcttgtg ggaatttcat
    20401 tttgcctttg cagcggtttt accgattgca acttatcgtg aattgcatga tcgtttgata
    20461 agaacttttg aggcggctga cattaaggta acctttgaca tccaagctgc tcaggtggat
    20521 tattcagatg atctgcttca agcttattac caagaagctt ttgagcatgc accgtgtaat
    20581 agtgctagtt ttaaatcttc tttctcaaag ctcaaagtga cttatgagaa tgacaaactc
    20641 attattgcag cgccaggttt tgtgaataac gatcatttta gaaacaatca tctgcctaat
    20701 ctggtcaagc aattagaagc ctttggcttt ggcaccttga ccatagatat ggtgtcagat
    20761 caggagatga ctgagcattt gaccaagaat tttgtttcca gtcgtcaggc tcttgtgaaa
    20821 aaggctgtgc aggataattt ggaagcccaa aaatcccttg aagccatgat gccaccagtt
    20881 gaggaagcca cacctgctcc taagtttgac tacaaggaac gagcagctaa gcgtcaggca
    20941 gggtttgaaa aagcaaccat cacaccaatg attgagattg agaccgaaga aaaccggatt
    21001 gtctttgagg gtatggtttt tgatgtggag cgtaaaacga ctagaacagg tcgccatatc
    21061 atcaacttta aaatgacaga ctatacctcc tcgtttgctc tccaaaaatg ggctaaagac
    21121 gatgaggagc tccgtaaatt tgatatgatt gctaagggag cttggttacg ggtacaaggg
    21181 aatattgaga ccaatccttt tacgaagagt ctcaccatga atgtgcagca ggtcaaagaa
    21241 attgtccatc atgagcgcaa agacctgatg ccagaagggc aaaagcgggt cgaacttcat
    21301 gcccacacca atatgtctac catggatgcc ttaccgacag tagaaagctt gattgatacg
    21361 gcagccaagt ggggacacaa ggcggttgct attaccgacc atgctaatgt gcaaagtttt
    21421 cctcatggct accatagggc tcgcaaagct gggattaagg ctatttttgg cctagaagcc
    21481 aatattgttg aggacaaggt gcctatttct tatgatcctg ttgatatgga tttgcacgaa
    21541 gctacctatg tggtctttga cgtggaaacc acaggtctat ctgctatgaa taatgacctg
    21601 attcagattg cggcttccaa aatgtttaaa ggaaatattg tagagcagtt tgatgaattc
    21661 attgatcctg ggcatcctct ttcagccttt accaccgaat tgacaggaat taccgataag
    21721 catttgcagg gcgccaagcc attggttact gtcctaaaag cttttcagga cttttgcaaa
    21781 gatagtatct tggttgccca caacgccagt tttgacgtgg gctttatgaa cgccaattat
    21841 gaacgccacg acttgcccaa aatcacacag cctgtgattg ataccttaga atttgctaga
    21901 aacttgtatc ctgagtacaa gcgtcacggt ttgggaccgc tcaccaagcg tttccaagtg
    21961 agtctagacc accatcatat ggccaattac gacgcggaag ccacaggacg tcttttgttt
    22021 atttttctaa aagatgccag agaaaagcat ggcatcaaaa atcttttgca actcaataca
    22081 gatttggtgg ctgaggattc ttacaaaaaa gcgcggatta agcatgcgac tatctatgtg
    22141 caaaatcagc ttggtcttaa aaatatgttt aagctggtca gcctttccaa tatcaaatat
    22201 tttgaagggg tgccgcgtat tccaagaacc gtcttagatg ctcacagaga ggggttgtta
    22261 ctaggaacag cttgttcgga tggggaagtt tttgatgccg ttctgactaa aggaattgat
    22321 gcggcggttg atttagctaa gtattatgat tttatcgaaa tcatgccacc agccatttac
    22381 cagccattgg ttgtccgtga attaatcaaa gaccaagcag gtattgagca ggtgattcgt
    22441 gatcttattg aagtagggaa acgagctaat aaacctgtgc ttgccactgg aaatgtgcat
    22501 tatctagagc ctgaagaaga gatttaccgt gaaattattg tgcgtagtct cggtcagggt
    22561 gccatgatta atagaacaat cggccgtggg gaaggggccc aacctgctcc cctacctaaa
    22621 gcgcacttta gaacaactaa tgaaatgctg gatgagtttg cctttcttgg aaaagacctc
    22681 gcttatcaag tggttgtgca aaatactcag gattttgcgg accgcattga ggaagtggaa
    22741 gtggttaagg gagacctcta taccccgtat atcgacaagg ctgaagagac ggttgccgaa
    22801 ttaacctatc aaaaagcctt tgaaatttat ggtaatcctc taccagatat tatcgatttg
    22861 cgaattgaaa aagagctaac ctctatcttg gggaacggtt ttgctgtgat ttatctcgct
    22921 tcccaaatgc ttgttaaccg gtcaaatgag cgaggctacc tagttggttc taggggatct
    22981 gtagggtcta gctttgtcgc aaccatgatt gggattactg aggttaatcc tatgccgcct
    23041 cactacgttt gcccgtcctg ccaacattct gaatttatca cagatgggtc agttggatct
    23101 ggctatgatt tgcctaataa agcctgtccg aaatgtggca ccccttatca aaaagatggg
    23161 caagacattc cctttgagac ctttcttggg tttgatgggg ataaggtgcc cgatattgat
    23221 ttgaacttct ctggtgatga ccagcccagt gcccatttgg atgtccgaga tatttttggt
    23281 gacgaatacg cctttcgtgc tggaacagtt ggtaccgtag cagaaaaaac agcttatgga
    23341 tttgtcaaag gctatgaacg cgactatggc aagttctatc gtgatgctga ggtggatcgt
    23401 ctagcagcag gtgctgctgg tgtgaaacga acgactgggc agcaccctgg ggggattgtt
    23461 gttattccta attacatgga tgtttatgat tttacccccg tgcaatatcc agccgatgat
    23521 gtaacggctt cttggcagac aactcacttt aacttccatg atattgatga aaacgtcttg
    23581 aaacttgata tcctagggca tgatgatccg accatgattc gtaaacttca ggatttatcg
    23641 ggcattgatc ctattactat tcctgctgat gatccgggag ttatggctct cttttctggg
    23701 acagaggttt tgggcgttac cccggaacaa attgggacac cgactggtat gctaggcatt
    23761 ccagaatttg gaaccaactt tgttcgcggc atggttaacg aaacgcatcc gaccactttt
    23821 gcagaattgt tgcagttgtc tgggctatct cacggaaccg atgtttggct tggtaatgca
    23881 caagatttga ttaaagaagg cattgcgacc ctaaaaaccg ttatcggttg tcgtgacgac
    23941 atcatggttt acctcatgca cgcaggctta gaaccaaaaa tggcctttac cattatggag
    24001 cgtgtgcgta agggcctctg gctgaaaatt tctgaggaag aacgtaatgg ctatattgat
    24061 gccatgcgag aaaacaatgt gcccgactgg tacattgaat cgtgtggaaa aatcaagtac
    24121 atgttcccta aagcccatgc ggcggcctat gtcttgatgg cccttcgggt ggcttatttc
    24181 aaggtgcacc accccattat gtattattgt gcttatttct ctattcgtgc gaaggctttt
    24241 gaattaaaaa ccatgagtgg tggcttagat gctgttaaag caagaatgga agatattact
    24301 ataaaacgta aaaataatga aggcaccaat gtggaaaatg acctctttac aaccttggag
    24361 attgtcaacg aaatgttaga acgcggcttt aagtttggca aattagacct ttacaaaagt
    24421 gatgctatag aattccaaat caaaggagat acccttatcc ctccatttat agcgttagaa
    24481 ggtctgggtg aaaacgtggc caagcaaatc gttaaagctc gtcaagaagg cgaattcctc
    24541 tctaaaatgg aattgcgtaa acgaggcggg gcatcgtcaa cgctcgttga gaaaatggat
    24601 gagatgggta ttttaggaaa tatgccagaa gataatcaat taagtctttt tgatgacttt
    24661 ttctagatta tcatgatggt agtcatatgc aaagtcataa aagaagaggg acaagatcac
    24721 tttctaatct ctctgatact aaactgtgac ataccgtata aagcgaggaa atcaaatgag
    24781 tcatttagat aagaacaccg ctttgaaagc catggtggtg tttcgtaaag ctcagcgaac
    24841 gctagatgct tttggggctg atatttttaa aaaggcagat ttaacagcca cgcagttcag
    24901 tgtgcttgaa gtactatata ctaaaggctg tatgcgaatc aatcacttga ttgattcttt
    24961 gttagcgact tcggggaata tgactgttgt actaaataat atggaacgca atggctggat
    25021 tagcaagtgc aaagacaaaa ctgataaaag agcctatgtg gttaccttaa cagataaggg
    25081 tactcgcttg attgaagctg ttttgcctaa acacgtcgca cgggtggaag aagcctttgc
    25141 tgttttgact gaaaaagaac aactttgtct gattgaactt ctcaaaaagt tcaaacaatt
    25201 ataaacaaat ctctttacag ctcttcttag agaagatata attactacat agtgataaat
    25261 ttcaaaaaga agtatcaatg aaataccact tttagaaagt tttaaaacga tctttaaaaa
    25321 aagaggacaa agagatgaaa catattttat ttattgttgg ctcgcttcgt gaagggtctt
    25381 ttaaccatca attagcggct caagcacaaa aagctctgga acatcaagca gttgtatctt
    25441 acttaaattg gaaagacgtt cctgttttga atcaagatat cgaagctaat gcacctttac
    25501 cagttgttga cgctcgtcaa gctgttcagt cagcggatgc tatctggatt tttacaccag
    25561 tttacaactt ctctattcca ggttctgtta aaaacctgct agactggttg tctcgtgctc
    25621 ttgatttgtc tgatccgacg ggcccatctg ctattggcgg taaggtggtt acggtctctt
    25681 cagttgcaaa tggcgggcat gatcaagtat ttgatcagtt taaagcacta ttgccgttta
    25741 tccgaacttc agtagcagga gagtttacaa aagcaactgt gaatcctgat gcctggggaa
    25801 caggaaggct tgagatttca aaagagacaa aagcaaactt gctatctcag gcagaggctc
    25861 ttttagcggc tatttagact aacaaaaaaa ggctaaaggg cctttttttg ttagtctaaa
    25921 atcaagagct cttctttggt ttcaaagggg tttttagcat tgatccgatc gtagaacaaa
    25981 acaccattga tatggtcaat ttcatgttga accacaatag cgttgtatcc ctttaatttg
    26041 atgcgatgct gttgtccttc tttatcatag tagtctactg taacacgagc atggcgaacc
    26101 acataccctt caacaacacg atcgacagat aaacaacctt cgccatcaga aagggctgca
    26161 tcttgaacag aatgagaaac gattttagga ttatacagga cttcttgcca gctataggct
    26221 tctttaggag gatttccttc tttatcagga agattaggaa cgagcacagc gatgatacgt
    26281 tttgacacat caatctgagg agctgctaga ccaacaccgg ccctaagtcc aagtttttcc
    26341 gccattacag gatcttgaga atgcttcaaa aattgcatca tcttttctcc taataggata
    26401 tcctcatcac acaagggtaa gctcacttct ttggcgacag ctcttaaagt tggattccct
    26461 tcacgaataa tgtcatccat ggtaatcaga tgactaggtt taattaattt atcttgtgca
    26521 gacatgtcta ctcctttact tttttttaac tggatttact atatcacaaa tcatttcttt
    26581 tttaaagaaa agtcaggtag tggttagagt gattgctatt ataagttaat gggctgcata
    26641 cctcagaggt cttaattgag ttagagcgtc taaatcggca atacgatagg ttttgaagca
    26701 gatgcgttcg ataatccgct gaaaaatggg ctgcttaagt acgtgcttaa gatggcgatc
    26761 acttgttcca aaacggtttg ctaataatgt aaggtttaga tgaacctctt ggttggcttg
    26821 cgcttcaagg gtataggaag caaagcgctc tttgacggta taggtaatgt tttgttggca
    26881 aacattttgt gtcaactctt gacctatgtc ataaaggcag gccgcatcgg ttaataagct
    26941 gtgttcatgg attagggatt gggtttgtta atactagagc aattaatatt atcagtgaac
    27001 actttattgg aaagaaatga atgactatgc taggctaccg cttatcagct gaagtgctgg
    27061 gatcagccat cttacctctt ttagctggtt atcttattag gcaagcaatc gcacaggttt
    27121 attctgattt aaaaacagcc tattggctat ttggccttgc tagttctgtt gcttatggtg
    27181 gtttggttaa agcaaaaaga gcacattcaa cgaccagata acctttttaa gcctagtgag
    27241 ggtttggatg tgagagctca gaataatagg ataacggttg acctaatatt atgaatctgc
    27301 tagaatagag tggtcgaaag acaaaccaac tttttcttgg ttttaggagt gccaatccta
    27361 agactcggat taagcaaaaa aaggagaata tattatggca atctcaaaag agaaaaaaaa
    27421 tgaaatcatt gctcaatatg cacgtcacga aggcgatact ggttcagtag aagttcaagt
    27481 tgcagttctt acatgggaaa tcaaccactt gaacagccac atcaaagaac acaaaaaaga
    27541 ccacgctact taccgtggat tgatgaaaaa aattggtcac cgtcgtaact tgttggcata
    27601 cctacgtcgt acagatgtta accgttaccg tgagttgatc caatctcttg gacttcgtcg
    27661 ttaatttcaa gtttaaaaag tcctctgctt atgcagtggg ctttttcatt tttgacatat
    27721 tgtttgttaa cttacatatt tggctagaat ggtctaagac tgttttttta gcagttgatg
    27781 attttattta acaacaaaag gtatctcagt gatgaggtat cttttgttgt atcatgaaga
    27841 aaaagggaat caattcccag atttgcctat ttttggccac cttttgagga acttgttaca
    27901 atgatatcac ctgttgagtc caattgcagt caaaaatgac gcgagacaat tggactcaat
    27961 ttgtcttgaa aatgaaaacg cttcatttta tactgacatt ataggaggag atgacatgct
    28021 atctcatgag ctcatcagaa actatcaact cttttctaaa tataaaggac attcactgga
    28081 ggcatttgaa tccatattaa agacaagcaa acgtcatata ctggcagata ttgctaaaat
    28141 caatgacacg ttgtcactct atcagttacc ccttattgct ctggacaggc agctggttta
    28201 tccgccagac cttactgaaa aggacttgtt gaatcgcatg ctacctacct tagacgacta
    28261 tctctttcaa aatgagcgtc tggatatgat tatcatttac atcatgatgg ctaaagaatt
    28321 tatctccatt aaccacttgg aaagtttgtt acggctcagc agaaattccg ttattgctga
    28381 tttaaacttg gtgcgtgatc gggtacaagc ttttcaggta actttagctt acaatcgcca
    28441 ggatggttat ttttttgaag gagaaccctt agccttgcgg cgtctcttag aatcagcggt
    28501 cagttctctt ttgcaagtca catcaggacc ttgggtgttc agttacttat tgcatgaact
    28561 tggtttgccc gaccagaaaa aggtgatggc agcaacgttg gaggaactga gcagggagaa
    28621 ccacttaact tttatttcgg agaaattgag ggatttgatt tattttttct gccttctcgc
    28681 tcatcgacca ttttcacgga atgtaagggc tgaagcagtg gatacttttc ctttagcttc
    28741 gccagctgtt gaaacgatgg tggaccagtt attggtcaac ttccccagtt taaccgaaga
    28801 aaaatatttg gttcaatcta ggttacttgg ttgtatccaa ggtgacttag agttagtctt
    28861 tcagcaacct atttatgaca ttatggagga aatcatcaat tcggtggcgg ttaacacggg
    28921 attgtctatc accgataccc cagaacttcg tcagaaccta tacagtcacc ttttgccagc
    28981 ttattaccga ctttactacg acattaactt gaccaatcct ttgaaggaac aaatcaaaca
    29041 agattatgaa tctctctttt acttggtcaa gcgcagcctt tctcctctag aaaaacaatt
    29101 ggggaaacta gttaatgaag atgaggttgc ttattttacc attcattttg ggagatggtt
    29161 gcaggcccct aagaagaggc caagcaatca gctggtagcc ttatctgttt gccctaatgg
    29221 cattagttcg tctctgatgt tggaggcaac cttgaaggaa ctttttccac agctacagtt
    29281 tattaggatt caccagctgg acaaaataaa gttgttggat ccagcatcct ttgatttgat
    29341 tttttcaaca gtagcttttg actgtgctaa acctgtttat gtgacgcaag ctttgatggg
    29401 acctgttgaa aaaatgatgt tgaaaaagat ggtctgtgat gactttcatc ttcccttgtc
    29461 agagcaattc gctttggatg atctgttgag tattattcat aaacacacca cgattactaa
    29521 taaagaagga cttgttagtg atttatcccg ttacctgatt ggtaaccatt taacgattga
    29581 aaaaggaggt ctaggactat tggacttgtt aacagcagat tttattaggc aggctgatgc
    29641 tgtttcggat tggcaggaag cgattcgttt ggctgctcag cctttactag aacaccagat
    29701 gattgaaaca tcttatatcg acggtatgat tgattcggtc aatgagcttg gggcctatat
    29761 tgttttagcc cctaaggtgg ctgttcctca tgcggcgcct aaaaaaggaa cgcggcagtt
    29821 aggcatgtct ctcttacaac taaaagaacc tgtcagcttt gatttgaagc aagaaggtga
    29881 tccagacaag caagtgcaat tgatttttgt tttgtctgct gtggattcta gttcacattt
    29941 gaaggctttg caggaactgt cgttgatttt agatgacgat gaacatattg agcaattaat
    30001 tgaggctaag aatactgagg aaataatgag tctgattagc catatgattg aaaaaggaga
    30061 tgaatcacat gattaaaatt gtaacggttt gtggaaacgg tattggtagt agcttgttac
    30121 ttcgcatgaa agtagaagct atcgcctcta gtttgggtat tgatgtggat gcagaatcct
    30181 gtgattccaa tgcggctgtt ggaaagggtg cagatttgtt tgttaccgtt aaagaattta
    30241 aagatatttt tccagaggat gccaaggttt gtatcgttaa aagctatacc aatcgtaaaa
    30301 aaattgaaga agatttggtt ccggttctca aggaaatgag tggcaaggaa taagccttta
    30361 aaggagatag gaagatacta tggaagcatt attatcattt attcgagata ttttaaaaga
    30421 acctgcattt ttaatgggct tgattgcctt tgcagggttg gtggctttga aaacacctgc
    30481 tcataaggtg ttgacaggaa ccttggggcc gattttggga taccttatgc ttgctgcagg
    30541 ggcgggtgtt attgtgacca atctggaccc tcttgccaaa ctcattgagc acggttttag
    30601 catcactggc gtagtgccaa ataatgaagc cgtcacttct gtcgctcaaa agattctggg
    30661 tgtggaaact atgtccatct tggtggttgg gttattgctt aatttggctt ttgctcgttt
    30721 tacccgcttc aaatacattt tcttaacagg acatcacagc ttctttatgg cttgtctctt
    30781 gtccgccgtg cttggagctg ttggtttcaa aggaagtctt ttgattatct taggtgggtt
    30841 cctcttggga gcttggtcag ctatttcgcc agccattggt caacagtata ctctgaaagt
    30901 gactgacgga gatgaaatcg ccatgggaca ctttggtagt ttgggctatt acctttctgc
    30961 ctgggttggt agcaaggttg gcaaagacag taaagatacc gaggaccttc agatttctga
    31021 aaaatggagt ttcttacgca acaccaccat ttcaacagga cttatcatgg tgattttcta
    31081 cttggtggca acagtggctt ctgttttgag gaatgcttca gtaacagaag aattagcagc
    31141 aggtcaaaac ccatttatct ttgctattaa gagtggtctt acctttgcgg ttggtgtggc
    31201 aattgtctac gccggtgttc gcatgatttt ggctgacttg attccagcct tccaaggtat
    31261 tgctaacaaa ttaattccaa atgctattcc agctgtagac tgtgcggtat tcttccctta
    31321 tgcgccaacc gctgttatca tcggttttgc gtcaagtttc gttggtggct tacttgggat
    31381 gttgatttta ggagttgcag gtggtgtcct gattatccca ggtatggtgc ctcatttctt
    31441 ctgcggtgca acagcaggga tttttggaaa ttcaacaggt ggtcgtcgcg gtgcgatgat
    31501 tggtgctttc gctaatggct tattactcgc cttcttgcca gccatgcttc tacctgtact
    31561 tggtaaactt ggtttttcaa acacgacctt tggagatgtg gatttcggtg ttttagggat
    31621 tttactgggc cgcttaggaa cgtcgattgg tcaaatcggt atttacttgg tggttgctgt
    31681 gcttgctatt gtattggtgc ttccaaactt tctgtcaaaa tctcaagaag ccatcaataa
    31741 tgtttcagaa gaaatctaaa aggaggatat gatgacaaaa aaactaaacg ttaaagtctt
    31801 ttcagacggt gcggtcttag agaccatgtt aaaggattta caaacaggtt tggtcacagg
    31861 ctttacaacc aatccaagtt tgatgaaaaa agcaggcatc agttcttata ttggctttgc
    31921 caaagaagtg cttgccaaaa ttacagacta cccagtgtcc tttgaagtct ttgcggatga
    31981 tctcgcaagc atggaaaagg aagctgagaa aattgccagt ctaggtgaca atgtctatgt
    32041 gaaaattcca gtcactactt caacaggcga atcaacttgt cccgttattc aaaagttgtc
    32101 agccaaaggc attaagttaa acgtcacagc catttttaca attgagcaga ctcaagctgt
    32161 ggttgatcat ttaaccgctg gagttccagc tatagtgtct gtttttgctg gtcgtattgc
    32221 agataccggc gttgacccaa tgccaatcat ggaagaagct ctacgcattt gtcgtcaaaa
    32281 agaaggggtc gaattgttgt gggctagtcc tcgtgaaact tataatatct atcaagctga
    32341 tcagctaggc gtggacatta tcacttgtac cactgatttg attgccaagt tgcctcttca
    32401 aggaaaagat ttagaagact attcccttga aaccgtgcaa atgtttctga aagacagtac
    32461 cagcctcggc tttaaaattt tagaggatga caatcagtaa tattaggaga cgaaagcagg
    32521 cataccaacc tgcttttttt gctttgttaa agagtataag tttcgtttaa tatttttcaa
    32581 ggacatttca agagattgcg atctgacagt gaaatttcta gtattttatg gtaaaatgta
    32641 gcagatacgt cgtttgatac aaagaggagc gtgtgacaag cgtggcaggt tgctttttgt
    32701 agcaaaacaa cgtataacaa ttgaatctaa gcagagaata ggtacctctt tacccctctg
    32761 aaaattaaaa ggagaatata tgtcaaaaca aacctttaca acaacatttg caaggaaacc
    32821 ccttgttgtt gaagttggtc aagtcgctaa gcaagccaat ggggcaaccg ttgttcgtta
    32881 cggagaatca accgttctga ccgcagctgt tatgtctaag aaaatggcaa cgggtgattt
    32941 cttccctctt caagttaatt acgaagaaaa aatgtatgcc gctggtaaat tcccaggagg
    33001 tttcatgaaa cgtgagggac gcccttcaac agatgcgacc ttgacagctc gcttggttga
    33061 ccgcccgatt cgtcccatgt ttgccgaagg ttttcgtaac gaagtacaag tgattaacac
    33121 tgtcctttct tatgatgaaa atgctagcgc tccaatggca gcgatgtttg gctcatctct
    33181 ggccttgtca atctcagata ttccatttaa tggaccgatt gcaggtgttc aagttggcta
    33241 tattgatggc gagttcatca ttaacccaga taaagaacag atggaagcgt cactcttaga
    33301 attaaccgtt gctggtagca aagaagccat caacatggtt gaatctggtg ccaaagaatt
    33361 atcagaagac atcatgcttg aggctctttt aaaaggtcac caagccattc aagaattaat
    33421 tgccttccaa gaacaaatcg tagcagttgt tggtaaagag aaagctgagg ttgaactgtt
    33481 acaggttgat gcagacttac aagctgatat tgtggctaag tacaatgctc aactgcaaaa
    33541 agctgttcaa gttgaagaga aaaaagcgcg tgaagcagcc acagaagccg ttaaagaaat
    33601 ggttaaggct gagtacgaag agcgttacgc agaagacgaa aacctagcaa ccattatgcg
    33661 tgacgtggca gaaatccttg aacaaatgga gcatgctgaa gtgcgccgcc tcattacaga
    33721 ggacaagatt cgtcctgacg gtcgtaagat tgacgaaatt cgtccgcttg atgctgtggt
    33781 tgacttcttg ccaaaagtcc atggatcagg tctctttaca cgtggtcaaa ctcaggcgct
    33841 atcagttttg accttggcac ccatgggaga cactcaaatc attgatggtc tggctccaga
    33901 gtacaaaaaa cgcttcttgc atcactacaa tttcccgcaa tattcagttg gtgaaacggg
    33961 tcgttacgga gctgctggtc gtcgtgaaat tggacacggt gccttaggtg aacgcgctct
    34021 tgaacaagtc ttgccaagct tagaagagtt tccttatgcc attcgtttag ttgccgaagt
    34081 tctagaatct aacggttcgt cttctcaggc ttctatctgt gctggtaccc ttgctctgat
    34141 ggctggtggt gtaccaatca aggctcctgt ggcagggatt gccatgggtc tcatttcaga
    34201 cgggacgaat tatacagtct tgaccgatat ccaaggtctt gaagaccact ttggagatat
    34261 ggactttaaa gtggcaggaa ctcgtgaagg gattacagcc cttcaaatgg atattaagat
    34321 tgcagggatt acgcctcaaa tcctagaaga agctcttgca caagctaaaa aagctcgctt
    34381 tgaaatcctt gatgtgattg aagcaactat cgctgaacca cgtcctgagt tagccccaac
    34441 tgcaccgaaa attgacacca tcaagattga cgtagacaaa atcaaagtgg ttatcggtaa
    34501 aggtggcgaa accattgata agattattgc cgaaacgggt gtcaaaattg atattgatga
    34561 cgaaggaaat gtctctatct actcaagtga ccaagctgcc attaaccgca ctaaagaaat
    34621 catcgctggc ctagtacgtg aagctaaggt aggcgaagtt taccatgcta aggttgtccg
    34681 tattgagaaa tttggtgcct ttgtcaacct ctttgacaag acagatgcac ttgttcacat
    34741 ttctgaaatt gcttggacta gaacgaccaa cgtgtcagat gtccttgaag tgggtgaaga
    34801 cgttgatgtt aaggtcatta agattgatga gaagggtcgt gtggatgcct caatgaaagc
    34861 tttgattcca cgcccaccaa aaccagagaa aaaagaagaa aaacatgact aaatcaaatg
    34921 aattagatat tcgcttaaga gcttttatca atgcgcctga taactttttg gatagccttg
    34981 cgcttgtcaa cgctttccat aattttcctg tctgggctgc taaagaaccc tacgtgatag
    35041 aagtcgaagg tgtcaaggtt acccctgttt ttaccgataa ggaagatatg gctcgcttta
    35101 aagaagaaca aaagagtgct caaagtcagt attggctgga gcgttcagct cttgcagtgc
    35161 tagacgaagt cattacatct ggtgcagcag gtcttgtctt taaccttaag aaaaagggag
    35221 attttgggaa ttctaccatt ttcaaaagca gtgacatgat tcaatttatg aaccattaca
    35281 ccactgtgtt aaatacgctt atgagtgatg acaatgtggc ggcagatacg atggaaaagg
    35341 tttaccttgt tcctgccttt gtttatccta aagatgataa ccattacgac cgcctttttc
    35401 ctaccatgtc aacgcctgaa ggaaaaagct atgttcccgc cttttcaaat cttcaaagct
    35461 ttgcgaaatg gtacaaccaa gacgattttg gaggcctttt caggaaagct gaaggagtga
    35521 ttctgacttg gacgattgat gatatttatc aaccaagaaa tggtgaaaac gagcttgatg
    35581 aaacgttcgg tgtcgccatc aatccttttg atgaccaaca aattcttgtt gattggtcag
    35641 aattagataa gtcgtaggag ttagtatggg ttggtggaaa gaaagtatag ctattgttaa
    35701 agctctagac ccagctgctc gtaatagtct tgaggttatc ctaacttatc caggcatcaa
    35761 agccctagct gctcatcgtt tgtctcattt tctttggcga catcatttta aattactagc
    35821 cagaatgcat agccaatttt ggcgattttg gacacaaatt gaaatccatc ctggagcaca
    35881 aatcgctcct ggagtcttca ttgaccatgg tgctggtctt gttattggag agacagcaat
    35941 tgttgaaaaa ggtgtgatgc tttatcatgg ggtgacccta ggtggaaccg gaaaagattg
    36001 tggcaagcgt catccaacga ttcgacaagg tgccttaatt tcggcacatg cccaagtgat
    36061 tggacctatt gatatcggag caaatgctaa agtaggggca gcagctgttg tgttatcaga
    36121 tgttcctgaa gacgtgacag ttgtaggtgt gccagctaag atagtacgag tgcatgggca
    36181 aaaagataat cgtcaaattc aaagtttaca aaaacaacga gaggtctctt atcagttgtc
    36241 aaaatgatcg gaaaataaca aaaagaagca ctgatgcctt ccaataaaat attttgggac
    36301 tttctagtag agtaatgttg aacttagcta gccctatcag tttggttgct gagtgtagtg
    36361 atatgggaat gttacaaaat acaaaaaacg cgtaaaagag catcaactaa gcaagtctta
    36421 gactgaagaa acagtctatt gtgatacttt ttctcaggtg gtgcttacgg cagcgacttc
    36481 ctttggaatt ctatgcctta gttttgagcc taaggtctca aaaatccgta tgggcatcac
    36541 tgtcagtatt gatgccactt ttaccacaac aaaaagcagc tgttttggct caccccacat
    36601 gcagaaatag gaaacctgat gtcaaatcag cagatctatt catgcttttt gagcataaaa
    36661 gtgggtttgt ctactttctg aagccttcac aggttgtgaa ggtttttcgt taataaagga
    36721 gcctcatgaa taaaataaga gttgggctgt atgtcattat gagtttgtct atccttgttt
    36781 ctagtattac actggtggct agtctaatct ttttactgag acaagacatg gttaaagcga
    36841 ttatatactt cattttgacc ctattttggt taataggttt ggttattaat attaaattgt
    36901 tgaaaaggtg gaatagcatt tcagaaaaag acttaggata tcaagatgac aactaatgct
    36961 aggatattga ataaggagtt tacatgatta aaatttatga taccatgacc cgttcgctcc
    37021 gcaagtttgt acctttgact gaaaatacag tcaatatgta cgtttgtgga ccgacggtct
    37081 ataattatat tcatattgga aatgctagat cagcggtcgc ttttgacacc attcgacgtt
    37141 attttgagta tactggctat caggtcaatt acatttccaa ttttaccgat gtcgatgata
    37201 aaattatcaa ggctgctact caagcaggtg tttctcctaa agaattgtca gatcgcttta
    37261 ttgcagcttt tatagaagat accaaggcac ttggtgttaa gccagccaca caaaatgctc
    37321 gtgttatgga ttatatagca gaaatcattt catttgttga aagcctcatt gaaaaagatt
    37381 ttgcttacga agcagatgga gatgtgtatt tccgcgtgga aaagtcagag cattatgcca
    37441 agctagctaa taaaaccctg tcagaacttg aagttggagc cagtggtcga acagatgctg
    37501 agacagcttt aaaagaaaat ccactggact ttgctctttg gaaatcagct aaggcaggtg
    37561 aggtttcttg ggatagcccc tgggggtttg gtcgtccagg ctggcacatt gaatgttctg
    37621 tgatggctac tgaaattctt ggtgatacca ttgatattca tggtggcgga gctgatttgg
    37681 aatttcctca tcataccaat gaaattgccc aatctgaggc caaaacaggc aagacttttg
    37741 ctaactattg gatgcacaat gggtttgtca ctgttgataa cgaaaaaatg tccaagtcac
    37801 taggtaattt tgtgaccgtt catgacatgt tacaaaccgt tgatggtcag gttttgcgat
    37861 tctttcttgc gacacaacag taccgaaaac caattaactt cactgaaaag gctcttcatg
    37921 atgcggaaat caatctgaag tatcttaaaa acaccttgca acaaccgctg acagaaactg
    37981 cagatgagca agagctaaaa cagtttgtaa tagctttcca agacgctatg gacgatgatt
    38041 tcaatacagc aaatgggatt accgtcgtat ttgacatggc caagtggatt aattctggct
    38101 cttatacaga acctgttaaa agcgcttttg agaaaatgtt agctgttttt ggcattattt
    38161 ttgaagaaga ggtgcttgag gttgacattg aagccttgat tgccaagcga caagaagcac
    38221 gcgcgaatcg tgattttgcc acagctgatg ccattcgaga tcagttagca gctcaaggca
    38281 tcaagctgct agataccaaa gatggtgtga ggtggctgcg tgactaatcc agttgatgtg
    38341 aatttgatta atggcattgc cctagccttt gaaggggatg cggtttattc ctactatgtt
    38401 cgtcgtcatc tcatttttca aggtaaaacg aaacctagcc agctacaccg tttagcaacg
    38461 agatatgttt ctgctaaggc acaagccaac ttgattcagg ctatgttaga agcgcagcta
    38521 ttgaccgaaa aagaagaaga catctataag cgtggtcgca ataccaatag ccatactaaa
    38581 gctaagaatg ccgatattat tacctatcgt atgtcgacag gttttgaagc cattatgggt
    38641 tatcttgata tgatgggcca aaaagagcgg ttagaagaat tgatcagatg gtgtattgag
    38701 tatgtagaaa agcaacaatt gatatcctca taagagtccc ctaggagact cttattttca
    38761 tagatctgaa gtaaaggtag agagccatta agtcttttta tgacatcaaa aagacataat
    38821 gatataaaaa agatacattt gtaataaaaa agacataaaa ataatgaaat cattttcgaa
    38881 tagtttataa tgagagggta agactaattt aaagaggaga tatttattat gacaactatg
    38941 caaaaaacag ttagcttatt atcactagct ttacttattg gtttgctggg gacttctggc
    39001 aaagccatat ctgtgtatgc acaagatcag cacactgata atgttatagc tgaatcaact
    39061 attagtcagg tcagtgttga agccagtatg cgtggaacag aaccttatat tgatgctaca
    39121 gtcaccacag atcaacctgt cagacaacca actcaggcaa cgataacact taaagacgct
    39181 agtgataata ctattaatag ttgggtatat actatggcag cgcaacagcg tcgttttaca
    39241 gcttggtttg atttaactgg acaaaagagt ggtgactatc atgtaactgt caccgttcat
    39301 actcaagaaa aggcagtaac tggtcaatca ggaactgttc attttgatca aaacaaagct
    39361 agaaaaacac caactaatat gcaacaaaag gatacttcta aagcaacgac gaattcggtc
    39421 gatgtagaca caaaagctca aacaaatcaa tcagctaacc aagaaataga ttctacttca
    39481 aatcctttca aatcagctac taatcatcga tcaacttcct taaagcgatc tactaaaaat
    39541 gagaaactta caccaactgc tagtaatagc caaaaaaacg gtagcacaag acaaaaatgc
    39601 tagtggacaa agaggaagta aaacctactt caaaaagagg attcccttgg gtcttatcag
    39661 gtctagtagt cagtttagct gcaggtttat ttatagctat tcaaaaagta tctagacgaa
    39721 aataaaagag tctatgcatt tattttgaag cattcatggt ataataaact catggaagat
    39781 aaagatacta ttgaaacaaa cgatatcgtc tatggtgttc atgccgttac agaaagcctt
    39841 caagcaaata caggaaataa gctttatatc caagaggatt taagaggaaa aaaagtggat
    39901 aacatcaaaa gcttagcgac acaaaaaaag gtcgctattt catggacgcc taaaaaaacc
    39961 ttgtcacaaa tgactgatgg agctgtgcat caaggttttg ttctgagagt atcagctttt
    40021 gcctatactg atattgatga gatcctcgaa atagcagagc aagaagcaaa tcctttgatt
    40081 cttattttag atggtctgac agatcctcat aatttaggat cgattttacg gacagctgat
    40141 gctacaaatg tatgtggagt gattattcct aaacatcgtt ctgttggtgt gactccagtg
    40201 gtttcaaaga cgtctacagg tgctgttgaa catattccga tagcgagagt aactaacctt
    40261 agtcaaactc tagataaatt gaaagcaaga ggattctgga tttttggcac agacatgaat
    40321 ggaacaccgt ctgattgctg gaacactaat ggtaaacttg ctttagtcat tggtaacgaa
    40381 ggcaaaggca tctctactaa tatcaaaaag caagttgatg aaatgattac gattcctatg
    40441 aatggtcacg tacagagctt aaatgctagc gtagcggcag ctattctcat gtatgaagtt
    40501 ttccgaaata ggcgctaaat tatgaaaaaa cggatattat tagtagatgg gtataatatg
    40561 attgcctttt ggcaatcaac ccgtcagttg tttaagacaa atcagcttga tcaggcacgt
    40621 aacacacttt taacaaaact taatcattat gcccattttg agaatattaa tattatttgt
    40681 gtttttgatg cccaatatgt accggggtta aggcaacgat atgaccagta ttatatctca
    40741 gtggtattta cagaggaaga cgaaacagca gatagctaca ttgagcgcat ggcagcagag
    40801 ttaaatacgg ctatacatat ggtagaagta gctacgagtg atttaaatga acaatggacg
    40861 attttttctc aaggagctct tcgtgtcact gcaagagaat tagagcaaag agttcatact
    40921 gtcaaagctg atttagataa aatgtctaga gatattgatc tcaaaacgcc taaactgcgg
    40981 ccttttgacc aaggacagct tattcaattg aaggatttta tgtctcagtt agatcgataa
    41041 tgagaattac gactcgccaa gtgcgggttt ttttgataaa ataaaacaat aattatttga
    41101 ttatcaaact aaaaaactgg atgaggagaa gtaagaatga cctttacaat aatgacagat
    41161 tcaaccgctg atttgaatca aacctgggca gaagatcatg atattgtcct tataggatta
    41221 acgattttgt gcgatggaga ggtttatgaa acggtcggtc ctaaccgtat tagtagtgat
    41281 taccttttga aaaagatgaa agctggcagt catcctcaaa ccagtcagat taatgtggga
    41341 gagtttgaga aggtttttcg tgaacatgct aagaacaaca aagcactgct ttatcttgct
    41401 ttttcttcgg ttttatcggg tacctatcaa agcgctctaa tggcacgcga tcttgttcga
    41461 gaagattatc ccgatgcggt gattgaaatt gttgatacct tggctgctgc aggaggagaa
    41521 ggctatctaa ccattttagc agcagaagcc agagatagtg gcaaaaattt actggagact
    41581 aaagatattg ttgaagcagt gattcctcga ctgcgcacct atttcttagt agatgatctt
    41641 tttcatttga tgcgtggtgg gcgtctgtca aaaggttcag cttttctagg cagtttagcc
    41701 agtatcaaac ctcttttgtg gattgatgag gaagggaaat tggtgcccat tgcaaaaatt
    41761 cggggacgcc aaaaagccat caaagaaatg gtggctcaag tggaaaaaga tattgcggat
    41821 tcgacggtta ttgtctctta tacaagcgat cagggtagtg ccgaaaagtt acgagaagag
    41881 ctgctggtgc atgagaatat tagcgatgtt cttatgatgc cactaggacc agttatctca
    41941 gctcacgttg gtcctaacac cctggcagtt tttgtgattg ggcagaattt ccgttaatcc
    42001 cttataagga ttgaagagaa atcctcaatc cttttttgct gcttaaatca atcaagaatg
    42061 taaaatatat ttgacaaaat atccaaaata atttgtatta tgtcatgtaa agatttaaag
    42121 gagaaacgaa tcatgtttga tagcaaacaa aatctcgcta agtcacaatg gatgtttata
    42181 atcataatag cagtgatgga tttggttgtg ttagtagcga cactgctggc taaaaccagt
    42241 tttcaacgtt acttagttgg aggcgtagcg gttatattga ctagctttct catattgttg
    42301 gtatgggggc taaagacagc gaaaaagctc caaacgagac tagacagcaa ggaagtacta
    42361 gattctaagg taagggacga tcagaagttg cccaaatatg atgaacgcca aaaacagatt
    42421 cttctcaaag gatacactat tgggttttgg tttatgattg tggttatctg gctgtcactc
    42481 tttattagcc gattcacaga gggactggta tctgcaagct tcctctttac gttggcttta
    42541 tggggagggt tggcagttca aacgacatat tgtaacctca acggtgcttc ctcatttgtg
    42601 gataggcgct ttggaaaaca aggaatacta atggggatga tagcaacagg aatgagctta
    42661 gtcgttatag gcttggcggt aagagagatg atgacaggac cgcttaaaat gggaagcttt
    42721 ttcaaggctg gcggcagtgg gactctgatg gtgttaggca taacgctcct tagtatggga
    42781 gctagtattt tctatcgtca ttatctggat gctaaagagg cagatgaatg aagaacctca
    42841 aattaaaagc agcgcgtgca ggcaaagatt tgtctcaaca agctctagta gatttggtag
    42901 gcgtctccag acaaaccatt gcggctgttg aaaaaggtga ttacaaccca acgattaatc
    42961 tttgcattgc catttgtcga gtgcttgata agaccttaga cgaccttttt tgggaagctg
    43021 atgattctcg ttaataccag cagagcagct ctgccattct cctaaatcga aagaaaaaat
    43081 aatccaataa aatcagctaa agcacttgac tggagcctct taagtttgat atcatagtag
    43141 gcggtattgt ttaccccatt tgaaaggccc cggaaccttc caaatacctt cgatgggacg
    43201 gaacacccat caccttgtaa acaaatatta cgaattcgta taggagaaat catgaacaaa
    43261 acaactttca tggctaaacc aggccaagtt gaacgcaaat ggtacgttgt tgacgcaact
    43321 gatgtgccac ttggacgtct ttctgcagta gttgctagcg tacttcgcgg aaaaaacaaa
    43381 ccaactttca caccacacac tgatacaggt gactttgtta tcgttatcaa cgctgaaaaa
    43441 gttaaattaa ctggtaaaaa agcgactgat aaagtttact acactcactc aatgtaccca
    43501 ggtggtttga aatcaatcac tgctggtgaa cttcgctcta aaaacgcagt tcgcttgatt
    43561 gaaaaatcag ttaaaggcat gcttccacat aacactcttg gacgtgcaca aggtatgaaa
    43621 ttgaaagtct tcgttggcgg tgagcacact cacgcagcac aacaaccaga agtacttgac
    43681 atctcaggac ttatctaaga ggaaaggagc attaaataat ggcacaagca caatatgcag
    43741 gtactggccg tcgtaaaaac gctgttgcac gcgttcgttt ggttccaggt actggtaaaa
    43801 tcactgttaa caaaaaagat gtagaagaat acatcccaca tgctgactta cgtttgatca
    43861 tcaaccaacc ttttgcagtt acatcaactg aaggttcata cgacgttttc gttaacgttg
    43921 ttggtggtgg ttacggtgga caatcaggtg cgatccgtca tggtatcgct cgtgcgcttc
    43981 ttcaagtaga cccagacttc cgcgattcat tgaaacgcgc tggccttctt acacgtgacg
    44041 cacgtatggt tgaacgtaaa aaaccaggtc ttaagaaagc tcgtaaagca tcacaattct
    44101 caaaacgtta attatcagcg atatatcaac gtttcaagac attcaagatt tttatcttgg
    44161 gtgtcttttt ttgctcgaaa atcaaaagtt tccaccaaaa tttccaccat attcccacca
    44221 ttactttttg aggtgcctat aagcagtctc tccagctgtc tgtgtgacag tactggtggt
    44281 attgatataa gtttttgtga ttgactggtc actatgggtt aatgcctccg atatttcttc
    44341 tagtgaacga cctgcttttt tggctagtgt agctccagta tgtctaagtt tatgtggtgt
    44401 tgcaggagct aattcagaat gtcgtctctt gattgagttc atacgataat tgaggtaatc
    44461 aatatgcaag acaacgttta tattgttttg tctatcattg taggtaaata caaactgatt
    44521 gtttgtttgc ttgatgccaa attgttttag ttcttctcgt tgcaaggctt tccatttttt
    44581 caacaactcc atcagttcag taggtgcatt gaataatgtg cgtttgcctc cctttgttgc
    44641 ttttacattt ccaaagcggt ctaaggcatt ttcgattagg atttcgttgt ttttgaagtt
    44701 aatatgcttc cattgaagag cataggattc agactttcta tcggacagaa aaaaagtagt
    44761 atagaatagg acataatcct tgaattctaa aagtcctttt tctaaatcat cgtcaaaggc
    44821 ttgcaaccaa aagcgcaatt catcttcatc taacgctaag tcttcttcac gtttattttc
    44881 ttttagtatt tgcttttttg ttgctttaat gcgactaatc gttttgtgta gtcgattgac
    44941 tgggatgtat tccagctctt ccgcccagtc aaaaacagag ttaatatatc cacggagagc
    45001 cttgaaattt gcaaaactat tagcttttgg tgtcagtaat gacagaacca attgtttgtt
    45061 ttcgttgaga taactcaagg agtatttacc tagaatgggt aatatatgta gtctaaagag
    45121 attttcggtt tgaaagattg ttgcagccgt aggaggctta ttcgtattag ttgtttgccc
    45181 agccttgtag ggttcaagac agacctcctt atagaaatca gaaaatagaa tatcttcttt
    45241 cttgagaggt tgttgaaaat gtttattgtg tctagctttt tcaatatcta ctgatagctt
    45301 taattcagct tctttagcct cacgtcttgt cttaaatcgt ttctcatata gcttacctag
    45361 tccaagtttt gcttgggtgt cttctggaat ataaactcta agctgatagg taccattttt
    45421 agttttcttt attgacatcg gcactccttt ctaggcagag atttcaagtc ttgccattca
    45481 atggttgacg ctttccttat tgaatcgtat ggatttaccg attttgatat atggtaatcc
    45541 catagaaatc cataggtcaa gagtattgtt agaaatccct agataatcac aggcttgtcg
    45601 tttatttaaa aaaggagaat cagcaccaac tgactctctt gcatttttaa cttctgattt
    45661 gattaactct ccaatcatgt gttggatttc aagagtttgt tcttctgcta aaataacttg
    45721 catggtcatt tcctcctata cgtagtattt aataaaaacg aaaacaagcc catttctgag
    45781 cttgtttcca aggagattat gaaaaagaaa agttatttag gatgaataca gtatatctga
    45841 atcaccctaa acaaatctta aatcataatc gtaaaaacta taaagaatcg taaaaattcg
    45901 taaatcttat tgtgcaaccg caaagctgta gtagctttgg ttgctgagga cggcgtaatg
    45961 tggtttgttt tgaacgccac cgacattaca ctctgagatg aggaaggttc cgtcttggtt
    46021 gacagcttcc acaaatgcga cgtgaccgta ttctgcatag gtgcctccgt agccaccttg
    46081 aacggacata acagcgccaa cttgaggctc tgatacttgt ttccagccac gagagacaag
    46141 actagccacc caatcttgac cattcccgtt gtagttgtag atagctgagt cggtacagat
    46201 gcctgtctca attaatctat tgcaaacata ccaggtacat tgaccagctg gataggtgtt
    46261 gtttccttga gttgtgaccg agttctcact agggactccg tatttgagtt ttccaaggta
    46321 ttctggtggt aagtcaaagg tagaagttag agtaccagta gcaagccctg tatcgcctga
    46381 taaagcgaca gaggagtctg aggtgattgt tccgtcaaac accttaaacc acttgtcagc
    46441 gtctgtttgg agcttctcag ccttggtctg accatctgag agtgcaacac cttcataatg
    46501 ttctgaccaa tacaaagcag catctccagg gtcagttgct ttttgcatct cagttttgac
    46561 ttttttatag gcaccgttta actcggttga catgagttgg agttcaacat cagcatccag
    46621 tgttcggctt gaagcctgtg cccagcggtc accattgacg gtattagacc atcccgacca
    46681 ttgcaagtaa ccagctactc caccgccagt gttgatagct tttgggtcaa atcctgattc
    46741 acgttctgca acggctaaac taccagttga accagccagg gtgaagcctt ctttggatag
    46801 ctggtaattg aggattttga tgacatcctc tgcccgttct tctgtgattg aggctttttg
    46861 agccacctct ttagctgtta gtgtcgtccg ctttccagtt gagctaccat tacttgatgt
    46921 gttagacgag tcatcagcta tcgcagctac acaaacgatg acaagtaata ggggcaacag
    46981 aagcgaagag agaagactca gtttgaatag ttttttcatg tgtccctatc acctccttta
    47041 gtgtttgaga tagactttaa agataactgt tccaaagagc catttggcat ctaggacggc
    47101 tggaatagca cgacagagtt cgataatccg tttggcttct tggtcattga cgggataaag
    47161 gatagtcact ttgatagctc tgaggtcatt ttcataggct tggtaaatgt acttttcaag
    47221 gacaggttga atctgacttc tcgtatatat cctaatagtg ttcattttgt tcacctcgca
    47281 atctgttgag ttcttgagtg agacgattct tgcgctcgat attggctttg attttgtcgt
    47341 ccctggtcat agtttgactg aaacttctag taaaggcgtt tgagccttgg gcttgataca
    47401 tggcacctgc atcatcatag gcgctaaatt ctctttccaa gcgttccatc ttccgttgtt
    47461 tacgtggaga tacccattgt tccttgagtt cctggaattc catttcaggt gatggaggag
    47521 tggttggttg actaggggtg gcttcaggag ttggtgtttt ttcttgggta ggattatctg
    47581 ttggaatatc ctgttttgga atgtgtggtt cagaggatgt tggtggcagt tggtcaggtg
    47641 ttggaccagg ttgctcagta ggctggtctg ttggaacgtt tggttccaca gctggctcac
    47701 ttggttttga ccgtctaaag aagttgccaa cttccttgat gtgagaagaa gcgttcatag
    47761 cacttccagc cacaaaacca ttaccagcca tggcaaagtt gcccaagtgt tgcgcagctt
    47821 caaagttacg tgacggcatc tgttggataa ggtctttacc ctgactaact ttgtcttcca
    47881 cttggtttcc aatgtcttcc atcttgatgc gagcccgtga gcccatgatg aattcaatga
    47941 gttccccttt ataaatccag aggaaataat agacggctgc tttagcaacg actgatagaa
    48001 tgagcttgaa gaggagggcg aatgttccta aagatgggaa agattcgatg accccatcaa
    48061 aaccagaggt aatcagcgtt tcaatgactt tttcgatgta gaagataatg agtgtgatga
    48121 gtgtcgtaat cgtcggaaaa acgagactac caaacatgac cttaaaaatc ccaaagatga
    48181 tgtcttgcat ggcagggaca aaggaaatga gaagagcgat agggaacagg aaaatcatga
    48241 ccaagactaa gagctgggca ataagattca gaagttgtac caggataatt ggaacctcaa
    48301 taacgatggc ttcaataatt ttgaagatga cgtagaaggt cttgatgaaa agataatccc
    48361 agacggctga tacccagcgg ttcttttctt tcccgtcatc agccttgtca ccaagtttgt
    48421 ccagataatc ttttctatct ttgtttttga ccgctacaaa tttccctgag tcatccacgc
    48481 ttcccaagac tttagaatca tcaaaggctt cctcttcacc tgtttggcta ttgacgtatt
    48541 ttccgttttc ttgacccgtg ttgacaaaaa cataggcagt gtaggaagtt tgtgcgatat
    48601 agctatcagc catagacttt ccgaccttga ttgatttatc ctcgccgtaa gagacagaga
    48661 tattggaaat ctttgaggtg acagtgtctg ctagattatc aaccgtatca aggatgtaga
    48721 gaccaccaga ggtagaagct acagttccaa agtaaccaaa tcctagtagg acaacgagaa
    48781 ggacatggag gacttttcgc atgaagtttc cacgagaaaa gaaatactgg tagaagaggt
    48841 aaaaggctcc gatggtcaga agcatggaaa ctagggaacc acttgataat ccgccagaaa
    48901 ttgaacctgt tagtccctgc cagatggatt tagcagcgtt atagacgtag gttttataag
    48961 agtcatagag gtcaatgttc tccatgatac gaatcatgag ggagaagaaa ccgaccacta
    49021 gattgagcag aaagaaaaag agattgacga aaatctcatt cattgccacg ataatggagg
    49081 tctcaattat tgatgtcttt tccagatacg attttaaggc gaagatgtcc acgcctttta
    49141 gtttctcaaa ggcttcttgc atgtgagcgc tcctttctaa ctagcatatt tattttcgag
    49201 gctagatgat accgttgctt tcattggttt tagaagcatg ttgatgtctt caaaaatgtt
    49261 gtgaatggaa atcatgttca gattgccata gacgtcatag tagaggcatt gccctgaaat
    49321 catgttgtca atccattcca ggttgctttc tgttggttcc agattgacgt gctttagaat
    49381 atcttctcgt tctgattttt cgtagaaggc aaagatggtt ccaaagccag tggtgtcatc
    49441 atcgttttca gcatcatgga cagattgtgt gatgagtacc agagtgttat ttttcgagcg
    49501 accgatacgg cgcatattct tgataacggc ttgaccttcg gcagacatca taagaatcca
    49561 ggcttcgtca aagaactcaa tagtgtcttc actttcattg cgttctccaa agtgggtaca
    49621 gaaagcaccg agggcaaaca taagggcgat agagtttcgt tcatggtctg aaatcttcgt
    49681 tgcgtctgtc ttaggtaatt tcaggttcgc aacttcaaga acggtgactt gtgactcata
    49741 attgagccct tacgttgttc catcagagaa ggcgagttcc aagatggaat tggtcacaat
    49801 agaagtgagg tagcgaccaa ctgaggcgat ttggtcattg tcactgtctt tgagcgcttc
    49861 cagaacgtgc ttaaagccaa cggtttgacc tgtttgcctc ttatcgacaa tgtcgttgat
    49921 ggtttcggta atggctgtct tctgatccat ggtgacgttg tcaaccgctt ggagcaagaa
    49981 ttccagcata ttcttagcga cctcaacagc ttgttcttta tctagtacga caatagggtc
    50041 aagcgctcca tggttggagg tgagcgagct atcgagagtg acaaagttaa aggcttcaat
    50101 ttgtttcttg cgttcaagat agagacgggc aaactcagca ctactgatga tttcttggta
    50161 gtgatggcgg agttcccgtt tggggtcaat ttagagtgtc ttcacgtttt gaagagcaac
    50221 tgacaggaag ataatctgag ctagaaagga tttcccttga cctgtagcgc ccgtaatgat
    50281 gatgtgtggg ttcttagtaa tcttgcctgc aatgtcttct ttattaccga cagtcgcatt
    50341 aaagaggaca atgtttttag aagcattgat ggctttttcg atgttgtccc aacgacttgt
    50401 ccagttatcg actcgtccga tataccaacc aatacggtta ctagcggatg tgttggtgaa
    50461 gggcatgagc tccgcaaatc cacgacttgt gaccatgtgt gtccaggttc gtgttttctt
    50521 ctgcaagtct tgaccgtaga gcaaagcttt gaagagataa ggtgtgtcat ggctagcctc
    50581 actgatttca acgcccatgt catcaaagta gttgaggaca acttgacggc gacttctcag
    50641 ctgactaagt gacgaaccag aaacaatgag ataagcacca tattcaatga tttcttcttt
    50701 gtttccgact ttcttcatca ggtctttcag tgagaatgag cccatgataa tttcgtcttg
    50761 ttggacggta tcggtatttt cagcttcttc catgatgttc ttgtagcgag tgttggagcg
    50821 tcccattttc cctttaattt tattacggtc aatgaattca gccttgaagc gtagttccac
    50881 gggaaagttg aggcgttgaa caaattctcc tagatggaag ccgttgaaga tggtgttgaa
    50941 ttttccaaca ggaagtatgg tcacaaaaga attgccatag ggactttcga gtttgagaaa
    51001 acctccgttc atgcttttaa tcaaggtgtc tgtggcattg aaaagggaac ggttatcgat
    51061 gacttctttc ttgaggtgtg gaatgtagcg gaggtattgc atccgttggt agtagaagag
    51121 ttcatcatct gtcagacgac gacaacgaag cgttgaaagc acttggtaga tgacttgttc
    51181 gtcagcgaga tagtcttcaa accagggctt ttcttcttct agttcaaagc ctagcccatc
    51241 tgctagggtc tctgaaatct cagagaatcg ttcataggcg aggtcagcaa gactagctcc
    51301 tttgtcatgc tttctcaatc ggacaccgac tagccagtca aattgataag ggatttccat
    51361 ttcatctgtc agtttatcga cagtatagag cagcaagtcc tcactaagtg tttgattatt
    51421 tggcgagaga gcatccataa agtcacgcgt cttttcttct aggagataat cctttggaat
    51481 aagtgagata tcaaagtgct ggtttttaac caattttttg agcatctgac tgaccgtgat
    51541 tttgtgcttt ccttttttct catcgtcagt aatagtgata ggtgtattag gaatacggta
    51601 gtaagccatg acttgcttgt ctttgcgaaa agctaagttt tcgtgtgtgg ctttaatagg
    51661 atattgtagt tttagtgcca tagagcctcc tttctaaagg tgtgtttgtt caaagacaat
    51721 gtcgtcatcg tcataagatt ccactcgctc atcatgatag atagcttttt tgttccatcg
    51781 gaattcatag aggtatcgga aatagtcagc tagaaagatg tgcattttct ttccgtgagg
    51841 ttcatattcc gtgtagaatt tggcgaactt gtaaggaacg taagcgtaga gcaacatgga
    51901 gatagagtgg gtgattttgg ctaatggaac aaggatgaaa gaaagtccca gaagcatgac
    51961 gacaaagacg agaatgaaaa caacaaaaaa ggacagctgc atcggtgttg cgaagtacca
    52021 gatacgtgcc cctttttgtg tcttgatttc ctgaatccag taaggagcgt ttagccccct
    52081 agcgtagtca tagagtggtt ctttctcgtt tttcatatca gagccccgtt tcaataccaa
    52141 agaggcgtag gaaccaacta atgacagaga gaatctgttg ccctttggtc atggacatga
    52201 tgattcccca aaatccgatg acggaaaaga gttggagcca ggagctgttt ttccaagcct
    52261 tgatggcaag aaggattgcc acagcagtga taatccaagc gccatctcct tggaggaatt
    52321 gttgtagtga gcttgtgttc atagatgtta ttctccttca tgttctgcat aatcttttgg
    52381 aatggtatga gccacttttg tgacgtagta ggaatttcct ttaggtgtaa gggtcagagt
    52441 gaaattctct gagcgagtgt tagcagcaac ttcaaaggtg acttggacat aagcggtaat
    52501 ggactcacca tcttctacca ggtagacata gtctagtgac ttgaaagtcg tgttttcaag
    52561 cacaactaaa tctttaccga ccaagtccag attgtcctgg tctgtggtgt agttggtaaa
    52621 gaagacgttg aggaattttt caactttctt gtgtgtcttt tctgggagat tgtcagaagc
    52681 ggtcagactg agcacagatt ctttgttaaa tcctttagct tgattgtcgc tcaagctaga
    52741 ataccaaggt agtccagaaa cgtaatagga gccattttta gaagcatagg ggatattaaa
    52801 tcctgtggcg atttcttcct ccttatcacc gactttttgc ttgtaggtca cttgataagt
    52861 ggcggtatta tccgtcagca ataataacct agctgagatc agagacatcg gtgttcgttt
    52921 ctgaccttgt gacttaatct caggttcaac gccatagaag ttattgagct tttcgatttg
    52981 ggcttcttgc tcctcagcct tatcagagaa agagaagtag gtggcgacaa agtcgttgag
    53041 gtaataggtt aagcggtaat cagtgttggt tgccgtagtc actacttgag aggattgagc
    53101 ttttttgact tccttttcaa gtgaggtgac cttgtttgat agcgtgatag cacgcaggga
    53161 accagaggct ccgacgaaaa ctaaacatcc taatccagta aggactagga tattcacgtt
    53221 tttccgtgtt gttttgatga gctttggtga gccacgcttc ttatcttgtt tcttgaaacg
    53281 agacaagtaa tgggtgactt gttggatgag tgttttcagt ttgttcataa ttcctcctta
    53341 tcaggcgcta gccagttcaa ttagcttatt gcctttggca tagagctgtt tgtggagttt
    53401 attgatttct ccgttgacat agtagtagcc acggagttcc agacggattt tttcgagaag
    53461 gtcagcaggt agcttttcgg cttcttcatt tttgagcagg tgattcagtt caccagcttt
    53521 tgttcaagct tccttgtctt tgtgtgcttt catgagctcg cctagttcaa gggaagcagc
    53581 tttgattttc ttctcaatga gtgattgttt tgccatgata atttcctcca tgaattgttc
    53641 ttgttggtct aagatgactt gtcgaaagag agtgaccagt ttggtgtcca tatttcgatt
    53701 aaagtctaag acttgaccat cagtggtaaa gtaggcgtgt tggtatttgg cgggagagtc
    53761 gaggtcaacg gtttcgcgag caaaggcatc aaagaaaaaa tccttttcct tcatgagtac
    53821 gatatagaga ttccagaact cattggtctc aggaaaacag gtgatgcctt cgtagatttt
    53881 tttgacaagc atgactcaga gatacctcct tatcattctt cgattaagtc atgatagccg
    53941 agagcttgat aaatgtagtc atcatcaaac cagagccagt cattgatttg cccctctgtt
    54001 ggtgtacttt ctgagaagac atcttcacag aggctagtga gttggtcaat tccgccacgt
    54061 tcacggacgg tgtctagggt ttctctagca cctgaccaag ctttgaaatt gtcgatgcta
    54121 gatagttcaa ctttatattc catgatgacc tccttaaaat ttgggtatca aaaaaaggca
    54181 actgaattca gttaccttgg agtgcttcac aaaaacaatt tagcgtaatc acttttcaca
    54241 ggaagtaggt gagtaacgta cacaatttta tcttccgtat tgatgttata gaaaagcagg
    54301 tatttgtggt tagcaatcac gatgccaaat gttttgtatt gtttagaaat ttgtcttcca
    54361 actttttcat ccgcatcaaa cccacgttca ggaaatgttt gaaggctttt aatgccttcg
    54421 aggagaagct gactggtttt caaagcagca tcaggactca acaaaacatc ttgaatatag
    54481 tttttgatgc ttttgatttg gtcaaaaatc gtttgtggga tattgacagt gtatctatcc
    54541 aagtagctcc gcctccattt cttcaatggt gacgtagtta cccgcttcga tttctgccat
    54601 gtttctatca atgatagcac caagctcatc aatcattttt tcacggataa gctcatcagt
    54661 agcttcttcc aagaggtttt ctttgcttgg gctaaagatg agtgtcccat cgctgccctt
    54721 atagacattg tattcttgac cttgtggaat ttcaaattct tttgggattg tgatacttag
    54781 agaattaccg atttgtcgtg ttttaactac tgtcatgttt tttctcctat gtgtttggta
    54841 tacaccgagt gtataccttt cttttgtttt tgtcaattga ttgtctcacc ctcctttttc
    54901 tttaggttat aggatgcttg caggtcttga agaatgcttt cagctctatc tgtaatttcg
    54961 ctgttttcct gaatcatctt aataaagtca gtctccatga ttttgtcagc ttcttccacc
    55021 agtttgagcg aattgacaac ctggtacatg agccatttga ttgttctatc aatggaataa
    55081 ggttcaggtt tcatcctgag tttcaagggg tctgtgccac caaacatccg ttgccatttc
    55141 tggtcaggaa caaaggcacc aaatttatta gtgccatcgt aaacctgcat ttcatgattg
    55201 ataatgccac gggcgatttc tgccaggtca acaccgctaa tgtattcttc aatagccagc
    55261 tgagcttttt cttgagcgaa acgcaactcg taacggttcc agataccaaa aatctccagg
    55321 gattcttcca cggagatttg ttcacttttg gcgagttcgt aacgtttttc atagaagttg
    55381 aagtagagat tactctggcg acttccaaaa taaagggaga taccttggct accttccacc
    55441 tcatccagat ttcttaggtt gccaccacca atgtgattcc aggttctgat gttcttaaaa
    55501 ctcacctcgt ctttatagac cttggcaatc atatcagaga gaagaaattg ttcgtcctct
    55561 ctgtcatgtc ccagatagcg ttcatccatg gcaatgtcta gtcgtgttac tcggctatct
    55621 gtgaggtcaa agagcagggc ttgaagaaat tcttgccagc tcatgtcgat actgtctagg
    55681 acaagttcca tttcacggca cccttgacca gagagttgta aggtcacttg gtaatttcct
    55741 gtttcgattt tgtcaaaaaa atcaaataac caaatattgc ctcgcttcca gagccttgtg
    55801 taattcagga gcctggtttc aaactctttg aactcggtga aggagcagtg aagataggtc
    55861 tgacagaagt gggataggtc acggattgac atgaaggtca tgcggaggta gtcgatatga
    55921 acatcaatca ggtcatcggt actatctttg tgatagccaa gttccgcttt gaattgaccg
    55981 aatttttcta ggcttaaacc gcgcgagcca tcttcatagc tacgataggt acgagtagaa
    56041 atcccaacag actccgcaaa ttgtttctga gtcatccctg tttgttttcg gaatttcttg
    56101 agatttagtg ggcttagctt atccattcat agggtaaacc tcctttctgg tgagtgacac
    56161 agttttttaa cgaaagtgac acacttggca aatctttgaa aaccttggta ccattggcgt
    56221 ggtgggggtt ggacgttgtc attttgacaa atgttacccc cctattagaa ttcgggggtt
    56281 gaatcacaat catgggcagt aggaactgcg agctacggtc tgcgcctgac gttgtcaggc
    56341 ttgcccttac tcttgtccta gcccatgatt tgcgagacaa ctttcaaccg cctttggata
    56401 agacttccgt ccttcctcct caaagagtgc caaggtttca agaagtagct gttcttgaaa
    56461 aggtgtcacg gcaagcgagt tttcctcttt gtcaaaagga atgcctcgct catccatgag
    56521 atagataact tttcggagtg tcttgactgt caggtcattt tccttggcaa aatctgtcag
    56581 caaacgtttt tcttccaaga cctccatgac atcatcttcc attggttcgt agtcttcttc
    56641 aataggttcc acatcttcca aggtgtcctt gtgtgtgaca agctgctcat cttctaggac
    56701 aggcaattcc ataaattcct cctcaaaaga aaagcctttg ttaaagggga cgtaaggaga
    56761 gaagaactct ccagctaact caccattatt ggcaatatag ccacatccgt gaaccttttt
    56821 accgttgatt ttatctagct ttttgaactc tttattgcgg ttagcctcgc caaacatcat
    56881 gttgtaaccc gtgtcttcca agtgtccgac agatagccgt ttcataaaat tatcccgaag
    56941 agcagtctta atatactcgc catcaggacg ttgcatggct tgaataacga aaagtccagc
    57001 ttgtcgtcct tccagaataa tctgggtcag gtattccgta gcttctgcct gtaggcggta
    57061 gtcattttca atcttagcga taaatgctgc ccactcatca atgacgatga acttaggctt
    57121 taatccataa tgggcaaagt tctttcctat cttgtagtca gggtgatttt gcatggtctc
    57181 ataacgattt tccatttcag taacattgtc tttgagacaa gtgataatat cgtctttgga
    57241 aatgaagact cgtctcttga atacaggaat gtttttaaga cctgataagt ctgcgttctt
    57301 cggatcgcac aggtctataa aaccaatctt tgccaaagcc aaaacaatag tcataaggac
    57361 aactgtttta ccactatcag ttcccccacc aatcagcaag tgtggctcag caacataatc
    57421 ccaaaagata tctttcatga ggcggatgcc ctggtcagtc agggtaactt ctgaaacgtt
    57481 aatacgggaa gcaatacgat tgatggcaat ttcatactga acaaagcgct catcaaaggt
    57541 tttgtttcta aagtcgccat tatacatgac ttcaagggta gctccaagat tgataaatca
    57601 gtcttggaat ttatttcctt cgagaataaa ggaagcaagc aactgatatt taccacgttt
    57661 gacataaact ttgggaaggg aaatcttttc aactgttttg ccatcacgtt tgactgtctt
    57721 tgaaagatag taccgatttt caaggagaaa gttagtcata atcctcagcg aattaaggcg
    57781 ctgaaagaag aggattttct ggtagagaat gagattgaca atcggtatta tcacgatagg
    57841 tggcagagta gtcagtagga ttttaggtaa ataaaacaaa gggtcagcga taatcaggtc
    57901 atagatagga tagtagtaaa aggctttacc aatcaaaaag ggcgataaca tgagaagact
    57961 tgttatcacc ctggtatgac ggtagaattt aaggacacga agtccccgat aggtaaagag
    58021 gtgcatgatt acctcctagt atcatttttt atcttctgct tttggttcag attttggagc
    58081 ggtttgagca ccttttttct taatggcaga agcgtagagg cggtagttat cgtttcgacc
    58141 gatagcagag taggtcacga caatatcagt gagttccact tcctcacgat aattgagccc
    58201 aaggtcattg agttgttgtt cagacatatc cacgatagtg aagaagagtg tttcgtgttg
    58261 gttagctgag tgaatcccaa cggtgatacc acggatttca ccagtcggaa cttggacgta
    58321 ggagccgtct tcgttacgct ggttacggtc tgcttcatag atgagttcag ccccttcaat
    58381 agagcggaag gtcagtttac caaagacctc atcgagtttt agagcatcgg tgattacacg
    58441 gtagctttta tcaacaattt ggagtttttc tccgaagttc aatccagttt tagccataat
    58501 ttttgagttc ctttcttatt tgacgatttc gagtttttcc gcaaagacgt taagagctgg
    58561 ggcaacgttt gagccattga cggcacggtc tgggaagaaa atagggatga tgactttgac
    58621 aagggtatct tcatcaaaga cggtgttagt tgcaggagta atgacatgga aagcaccatg
    58681 ttcttggctg ttcagcacat gacgttggta tttgccttct ttgccaaaga cagtacgtgg
    58741 agcattcccc agtttttcat agtaagcatt tccgataaat tcaggtttca taacaagtgt
    58801 ttcaggaatc ataagtgttc tccatttcta tttttgggta ataaaaaaat cagcacatca
    58861 cagggctgac ttgagcaaag taaaagcgat tgattttaga tttataaaga cggctataag
    58921 agtttagttc agccatcgga tagcctactc gttgaaattg cgtaatgagt ttgtcaattt
    58981 cgtctttagc tgagacaaag agactagctt gtaggtctgg gtgttgagcg tacatgttat
    59041 gggtaaaaca ataattttga aaatggcgct caagtgtttt ggcaaaatat gaggtcataa
    59101 aagcctcctt tcttattgta acaagaaaag ctactagaaa catccagtag cttgagcata
    59161 gactactcct gtaaaacaaa gagaagtagt ccttttgaaa aagggttatt tggttgaaag
    59221 acctatctag gaactagata aatctttcac ggtggcaacg tttagcaagg tgctttgcgt
    59281 taattaccat cgctttccca gccaatcatt caggtagtca ttatcatgcc tatcacgatt
    59341 ctcttacgcc tctttagaat tattttacta tctcaacttc aaccacacgc caaacgcatg
    59401 aagaaac
//
LOCUS       DATTYN010000008        59073 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.08, whole genome shotgun sequence.
ACCESSION   DATTYN010000008 DATTYN010000000
VERSION     DATTYN010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59073
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.08"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(115..1251)
                     /gene="dnaJ"
                     /locus_tag="VB649_000667"
     CDS             complement(115..1251)
                     /gene="dnaJ"
                     /locus_tag="VB649_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEP1669635.1"
                     /translation="MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTA
                     PVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDI
                     SFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI"
     gene            complement(1532..3358)
                     /gene="dnaK"
                     /locus_tag="VB649_000668"
     CDS             complement(1532..3358)
                     /gene="dnaK"
                     /locus_tag="VB649_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEP1669636.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFD
                     DLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK"
     gene            complement(3539..4111)
                     /gene="grpE"
                     /locus_tag="VB649_000669"
     CDS             complement(3539..4111)
                     /gene="grpE"
                     /locus_tag="VB649_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEP1669637.1"
                     /translation="MAVFNKLCKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEETP
                     EKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDN
                     LERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDE
                     HPADSIAEVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(4114..5148)
                     /gene="hrcA"
                     /locus_tag="VB649_000670"
     CDS             complement(4114..5148)
                     /gene="hrcA"
                     /locus_tag="VB649_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001872861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEP1669638.1"
                     /translation="MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLE
                     DMLQKASHILSEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQ
                     FAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFD
                     YVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADS
                     QEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYR
                     YLNSNHYEVH"
     gene            complement(5283..5852)
                     /locus_tag="VB649_000671"
     CDS             complement(5283..5852)
                     /locus_tag="VB649_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP1669639.1"
                     /translation="MRKRLKFPYFLTLLACFLLLIVCPLLSSQRIASADKEVRVNYSQ
                     KQFITKMGKEVKPLAKYYGIRPSILIAQILLETHDGKTLLASKYHNLFSKKATPGQAA
                     ITLKSPKQTNQNVRYAIYKDDASAIRDYLRMLRQGKEVDKRLYRNLATEKGYKAPAKS
                     LQKYLHYTDKTYARRLIQVIESNDLTNYD"
     gene            complement(5849..6592)
                     /locus_tag="VB649_000672"
     CDS             complement(5849..6592)
                     /locus_tag="VB649_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEP1669640.1"
                     /translation="MKYNSLNYLVQLLIVIVFLGGLYLFIKPEESVTPTQLNKKEIQQ
                     KDIKKTDRLRALPKVSVEDWELVLVNRDHITKEMSPELADINGISVDKRIEQATSDFL
                     AAAQAIDSQEHLISGYRSVDYQTELYQSSIKKEMANDPTLTQEAAEALVQTYSQPPGA
                     SEHHTGLAIDMSTVDTLNASDPSVAKAVQKIAPDYGFVLRFPEGKKTSTGVDYEDWHY
                     RYVGKASARYMVQHNLTLEEYIAALKEKR"
     gene            complement(6582..7289)
                     /locus_tag="VB649_000673"
     CDS             complement(6582..7289)
                     /locus_tag="VB649_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEP1669641.1"
                     /translation="MTKTRLYIARHGKTMFNTIGRAQGWSDTPLTKKGEEGIRELGLG
                     LKDATIPFKAAFSSDSGRTMQTIEIILRESENEFLPYTKDNRIREWCFGSLEGTYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLRKRIWEGFEAIAL
                     SIQNAGGGNALVVSHGMTIGTFLWLIDPDRDKQYIDNGSVTVVEFDDGQFTIKTIGDM
                     SYRYRGREIIEERSDEI"
     gene            complement(7681..7920)
                     /locus_tag="VB649_000674"
     CDS             complement(7681..7920)
                     /locus_tag="VB649_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEP1669642.1"
                     /translation="MIWSLIVGAFIGMIAGKMTEKSQSMGCFTNIIAGLIGSAVGQRL
                     FGDWGIQLAGMAIFPSILGAAIVIVLVSAIFGKRY"
     gene            complement(8139..8355)
                     /locus_tag="VB649_000675"
                     /pseudo
     CDS             complement(8139..8355)
                     /locus_tag="VB649_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991523.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8352..9791)
                     /gene="gatB"
                     /locus_tag="VB649_000676"
     CDS             complement(8352..9791)
                     /gene="gatB"
                     /locus_tag="VB649_000676"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEP1669643.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPD
                     LPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVS
                     LGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALIPENLVEMIAIIADGTISSKMAKKVF
                     VHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELQKLRD"
     gene            complement(9791..11257)
                     /gene="gatA"
                     /locus_tag="VB649_000677"
     CDS             complement(9791..11257)
                     /gene="gatA"
                     /locus_tag="VB649_000677"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEP1669644.1"
                     /translation="MPFNHKTIEELHDLLVAKEISATELTQKTLEDIKSREEAVGSFI
                     TVSEEAALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTV
                     KENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKE
                     TVLAAAKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDA
                     KNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIEDFDKVFA
                     DYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVG
                     LQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK"
     gene            complement(11257..11559)
                     /gene="gatC"
                     /locus_tag="VB649_000678"
     CDS             complement(11257..11559)
                     /gene="gatC"
                     /locus_tag="VB649_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEP1669645.1"
                     /translation="MKISEEEVRHVAKLSKLSFSESETTTFATTLSKIVDMVELLNEV
                     DTEGVAITTTMADKKNVMRQDVAEEGTDRALLFKNVPEKENHFIKVPAILDDGGDA"
     gene            complement(11791..12126)
                     /locus_tag="VB649_000679"
     CDS             complement(11791..12126)
                     /locus_tag="VB649_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dikinase"
                     /protein_id="HEP1669646.1"
                     /translation="MKERYFFCDVVGKCLEEYVDRGIFDKEPFQTFDQKGIGRLFSTA
                     VSLARSVKPDLKLGICGEHGGDPASIAFCHSQGLTYVSCSPFRVPLTRLAAAQAAIKA
                     SGHSLTQDK"
     gene            complement(12570..13124)
                     /locus_tag="VB649_000680"
     CDS             complement(12570..13124)
                     /locus_tag="VB649_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEP1669647.1"
                     /translation="MRALISIDYTNDFVADDGKLSAGKSAQAIATKIAEVTKTAFDQG
                     DYIFFAIDCHDQNDPWHPESKLFAAHNIKGTTGRHLYGPLAEVYSHMKQHPRVFWIDK
                     RYYSAFSGTDLDIRLRERGITQLVLTGVLSDICVLHTAIDAYHLGYQLEIVKSAVASL
                     TKESYEWSLAHFEQVLGAKLINDY"
     gene            complement(13271..14053)
                     /gene="codY"
                     /locus_tag="VB649_000681"
     CDS             complement(13271..14053)
                     /gene="codY"
                     /locus_tag="VB649_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEP1669648.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIF
                     PVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
                     LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF"
     gene            complement(14271..15485)
                     /locus_tag="VB649_000682"
     CDS             complement(14271..15485)
                     /locus_tag="VB649_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEP1669649.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPA
                     AFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
                     IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGK
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYL
                     FPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQ
                     EKITRVLYQYRR"
     gene            15716..16168
                     /locus_tag="VB649_000683"
     CDS             15716..16168
                     /locus_tag="VB649_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEP1669650.1"
                     /translation="MSLKYKRILVAIDGSYESELAFNKGVNVALRNDATLLLVHVIDT
                     RALQSVATFDTYIYEKLEQEAKDVLDDFEKQAQIAGITNIKQIIEFGNPKNLLAHDIP
                     DRENADLIMVGATGLNTFERLLIGSSSEYIMRHAKIDLLVVRDSTKTL"
     gene            complement(16291..17679)
                     /locus_tag="VB649_000684"
     CDS             complement(16291..17679)
                     /locus_tag="VB649_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP1669651.1"
                     /translation="MTVKAVFFDIDGTLLNDRKNIQKTTQKAIQQLKKQGIMVGLATG
                     RGPGFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSMIYKVIRYANEKKREIS
                     LGTASGLAGSRIIDMGTSPFGQVISSFVPKSWARTVEGSFKHLIRRIKPQSFRNLVTI
                     MREPIYQVVLVASQAETKKIQEKFPHIKITRSSPYSLDLISVDQSKIKGIERLGEMFG
                     FDLSEVMAFGDSDNDLEMLSGVGIGIAMGNAETVVKDGAHFTTDSNNNDGISKALAHY
                     GLIHFDVEKSFKSRDENFNKVKDFHRLMDSDTIETPRSYTISEAGYRSGFKVEEIVEF
                     LYAASKGDQQQFTQAIFDLHGAVDQAANKVQAKKHVETPLIGQVDALADLLYFTYGSF
                     VLMGVDPQPIFEAVHEANMAKIFPDGKAHFDPVTHKIQKPDYWQERHAPEVAIKKELD
                     KQLQKSLQRFDK"
     gene            17751..18716
                     /locus_tag="VB649_000685"
     CDS             17751..18716
                     /locus_tag="VB649_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEP1669652.1"
                     /translation="MKKILVLHTGGTISMQADNSGRVVPNQDNPMTKIHAAAQDIQLT
                     VSDFLNLPSPHITPHHMLSIYHHIQERTDVFDGIVITHGTDTLEETAYFLDTMALPTN
                     IPVVLTGAMRSSNEVGSDGIYNYLTALRVASSDKAKEKGVLVVMNDEIHAAKYVTKTH
                     TTNISTFQTPTHGPLGIIMKNDLLFFKTAEPRIRFDLRCISGTIPIIKAYAGMGDGSI
                     LSLLTPGSIQGLVIEALGAGNVPPLAVGEIEHLITLGIPVVLVSRCFNGMAEPVYAYE
                     GGGAMLQEAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(19065..19769)
                     /locus_tag="VB649_000686"
     CDS             complement(19065..19769)
                     /locus_tag="VB649_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669653.1"
                     /translation="MISYLKADLFRIRQERLALFSCMLLVVIAVGVAYSFRKTPNQVI
                     MIQIINIITDFVTLFFLTPARIFFSDDYNYRTINNVVVKQQNRTLIIIYKLLVSFGLS
                     LLFISLTYLLSALAFHLFTGQAYYGIVIDRMIKQLPFYIAIIALCQFLFNILRKTYQS
                     ITAYILYVLLFDKVSATLANHFFKLDISPVLMFKHLSLSLGDKHLSSTSILVAFGLTL
                     CYLLGNVFLFSKRELK"
     gene            complement(19782..20684)
                     /locus_tag="VB649_000687"
     CDS             complement(19782..20684)
                     /locus_tag="VB649_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669654.1"
                     /translation="MTQQSMLLSIEQVNKSYGKNQVLSDISFDIYKGEICGLVGQNGA
                     GKTTLMRILSGLIGKDSGQIKQLQPYRMGSIIESPTLYPNMTAHDNLYYAALQLRLAD
                     AKERIHEVLELIGLEKVSKKKKVKDYSLGMRQRLAIGLSILDFPEFLILDEPINGLDP
                     AGIKEMRQIILNLRDCYGITILISSHILSELDLVVDRYVIMHKGKVIKSMDKAELKAQ
                     VKVQIALHTSDDQLVKNRLLELGLRVETDGQMLLIKPTLSVMELIKIVLDLPVEIFDI
                     YHHQVSFEHYYLDLLGKDAASPLI"
     gene            complement(20976..22991)
                     /gene="recG"
                     /locus_tag="VB649_000688"
     CDS             complement(20976..22991)
                     /gene="recG"
                     /locus_tag="VB649_000688"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEP1669655.1"
                     /translation="MILTAPMSNLKGFGPKSAEKFQKLDIYTVEDLLLYYPFRYEDFK
                     SKSVFDLVDGEKAVITGLVVTPANVQYYGFKRNRLSFKLRQGEAVLNVSFFNQPYLAD
                     KIELGQEVAVFGKWDATKSAITGMKVLAQVEDDMQPVYRVAQGISQSTLIKAIKSAFE
                     IDAHLELKENLPATLLEKYRLMGRSQACLAMHFPKDITEYKQALRRIKFEELFYFQMN
                     LQVLKAENRSETNGLPILYSKHAMETKISSLPFILTNAQKRSLDDILSDMSSGAHMNR
                     LLQGDVGSGKTVIAGLSMYAAYTAGFQSALMVPTEILAEQHYISLQELFPDLSIAILT
                     SGMKAAVKRTVLAAIANGSVDMIVGTHALIQDSVQYHKLGLVITDEQHRFGVKQRRIF
                     REKGENPDVLMMTATPIPRTLAITAFGEMDVSVIDELPAGRKPIMTRWVKHEQLGTVL
                     EWVKGELQKDAQVYVISPLIEESEALDLKNAVALHAELSTYFEGIAKVALVHGRMKND
                     EKDAIMQDFKDKKSHILVSTTVIEVGVNVPNATIMIIMDADRFGLSQLHQLRGRVGRG
                     HKQSYAVLVANPKTDSGKKRMTIMTETTDGFVLAESDLKMRGSGEIFGTRQSGIPEFQ
                     VADIVEDYPILEEARKVSAAIVSDPNWIYEKQWQLVAQNIRKKEVYD"
     gene            complement(23365..24819)
                     /locus_tag="VB649_000689"
     CDS             complement(23365..24819)
                     /locus_tag="VB649_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669656.1"
                     /translation="MERLGGADLDYCYHNHHDTSMISAEQLVFTYHDQKNPACQVSTC
                     QIASGQFIVLCGPSGSGKSTFLKLLNGIIPDYYAGKYEGRLDVADCQAGRDSVETFSR
                     SVASVFQNPASQFFYREVQHELVFPCENQGLDAKVIMKRLWTLAEDFAFAELLNKDMF
                     GLSGGQKQRVAIATAIMQGTNIMLFDEPTANLDSAGIAAVKAYLTQLKAAGKTIIVAE
                     HRLHYLMDLADNFFYFKNGRLTDKLTTQDLLALTDEQRQDMGLRRLDLSDLKPVLAGK
                     IESQHYRPDDSLCIEHLTVRAGSKILRCIEQLSFAAGSISGITGSNGLGKSQLVYYIA
                     GILDDKKATIKFQGIPLSAKQRLSKTSIVLQEVSLQLFAESVSKEVNLGHERHPRTTE
                     VIERLSLTTLLERHPASLSGGEQQRVMIAASLLADKDILIFDEPSSGLDLLQMKALAN
                     LLMQLKTQHKVVILISHDEELLSSVCDTIYQMLP"
     gene            complement(24756..25436)
                     /locus_tag="VB649_000690"
     CDS             complement(24756..25436)
                     /locus_tag="VB649_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEP1669657.1"
                     /translation="MRLDVRTKLLLLVLANACFFFRVDGFLEFIIVIFLLLLLSALNK
                     KKLAFKLAVVYLLMIGLSVIPLSIFPSYLDHLLSFVSIAGRLVFPSLLAGLITIKTTT
                     IYELVHGLRKWHFPEVWLLTLAVMCRFIPMIRQECCVIHRSLTIRGIILTKWSILIRP
                     KQYLEYLMVPLLLSLIRSSQELTIASLTKGLAVNKGTSECFSSHLTWKDWGVQIWITV
                     IIIITILQ"
     gene            complement(25433..26026)
                     /locus_tag="VB649_000691"
     CDS             complement(25433..26026)
                     /locus_tag="VB649_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEP1669658.1"
                     /translation="MKQLTIKDIMITGAFAALYFICVGLGTFINIFFDRSGNMLYAPA
                     FAALLGGTIYFLLIAKLQTFGPITLLGLMMGGFFFLSGHFFAAMFPSIIFGLIADIIA
                     SLGKYKSRFFNDLSYMVFAFVNSGPILLMWLLKDAYVESLLARGKSMTYVNRIMYDFS
                     LGHVIWFVGIVLAGALLGSAFAHYLLKKHFIKSGLLS"
     gene            complement(26023..27693)
                     /locus_tag="VB649_000692"
     CDS             complement(26023..27693)
                     /locus_tag="VB649_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669659.1"
                     /translation="MAKPNRSTLSLVWRLLTLMKTLLPWIILAVGFAVMGFVITVSIP
                     TGIAYLGLLAIRQEVIPILALYLLIALAFLRGFVRYGEHYFGHFVAFHSLAAFRNLIF
                     KKLRALSPACLDSQDSGYLLKMIGEDIEALEVFFAHTIAPICTAILSAGLMFWYFCQS
                     SWQLALLALATYACLAIVIPIYFANILQVLLKSQNEGRKDYLSYFLESLRSVKDLLQF
                     QVLDEQFERLIKKSNHVNALDRNVAQAQFLQMALTFFWLGLMILAFSYMVFDGICRDS
                     LSFDKGLLTFIAFTASFSPFLELGRLPLGFKRAMNAARNIFNLLDENVIVDEGTKQID
                     RLRSVSFEDLSFAYPKRQELVFKDLSVTFQEKGIIGIKGESGSGKSTLVKLIMKWYNW
                     KTGDIFLNDRNSCLLNAAKLQDTIAYVPQTAQLFQQSIRENLTFGRQDISDESIWNLA
                     EACGMKDRLLACKEGLDTIIKSPSDFSAGEGQRLELMRALLKDASCYIFDEPTSNLDS
                     LNEAILLDLIKTHCQGLVFLISHRPSTLACADHLFCVKNGFLKEVNKK"
     gene            complement(27686..29449)
                     /locus_tag="VB649_000693"
     CDS             complement(27686..29449)
                     /locus_tag="VB649_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEP1669660.1"
                     /translation="MMETEDTISRGKRKRLLKRLRERIAPKRYLLYVSAFLSWLQFVM
                     RMISFYLIAKTFSTFILGHAIALGRLAGLLLLLNVVGFVLAILGKQLQGIASQFARDS
                     LKQSFFEAFIDLDGQFDAHASDADILTLASQGIDSLDTYYGYYLSLSMRTKWNCTTIM
                     ILVFLIYPLAGLVFLGVLPLIPLSIVAMQKQSKQIMSHYWSSYMDVGNLFMDDLKGLN
                     TLYSYQATERYEQEFSGKAEQFRKATMSLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LATGQLSFFNFLFFLLIATEFFTPIREQGYGMHLVMMNTKMADRIFSFLDSIPARKDN
                     KSKTAINFNQIDIQNISLAYEKKTVLSGVTMTLTKGQLTAIAGVSGQGKTSLAQLLLK
                     RQSATTGHILFDGLDSDNLSQETINQQVLYVSDQSTLLNRSIYDNLRLAANLSKKEIL
                     DWIDQHGLLSFINWLLDGLDTIVGENGNLLSPGQKQQVICARALLSKRSLYIFDEATS
                     SLDAENERIIDNLITRLAKTAIVIVITHKMSRLKGANQVLFLNTGQPACLGKPCDLYR
                     DQPTYRHLVDTQARLEASIYG"
     gene            complement(29446..30282)
                     /locus_tag="VB649_000694"
     CDS             complement(29446..30282)
                     /locus_tag="VB649_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669661.1"
                     /translation="MSKNSSHIRVQNLSFAYEEKLVLDDLTFSIPKGKITTIMGANGS
                     GKSTLLQLLTKNLPLKQGQVWLEQEELATISLKAFAKKVAVVHQYHQVVEGLLVGELV
                     AMARLARRSFFKTTTKEDEERLAWALEVTALSDYVYRDIQHLSGGEQQRVWIAMALAQ
                     DTDIIFLDEPTTYLDIKYQLDILTLITKINQELGLTIVLVLHDINQALSLSDHLIGLK
                     DGRLYAQGQPRDLLDQQFIRDVFGVELPFVERNGQQFVLTSLVNETNDIRTQWRDRNK
                     NR"
     gene            complement(30279..31301)
                     /locus_tag="VB649_000695"
     CDS             complement(30279..31301)
                     /locus_tag="VB649_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEP1669662.1"
                     /translation="MTASDLQRDQSLLAKKRFRSGLYLVLLILSLLFLAVIALSLGGL
                     AVSYEAIIKGLFVAYDPQVALIYDLRFPRIVIALLAGAGIAVSGVLFQAVLKNPISDP
                     AIIGICSGASFMVLVSSLLLPQLLLYGPIVSFLGGGVSFLLIYGLAWKKGLNPIRLIL
                     TGIAINALFMGLSTALTSFFTSASPMVNALLAGHISQKTWADVGVLFPYTFIGLLLAL
                     LLSKTCNLLLLDDQVIRHLGIDATALRLGISLVAVLLASVATSIVGVVSFLGLIVPHM
                     SRLLVGSKHQILIPFSALLGAFVFLLADTLGRSLAYPLEISPAIIMSIVGGPYFIYLL
                     RRSDII"
     gene            complement(31303..32187)
                     /gene="isdE"
                     /locus_tag="VB649_000696"
     CDS             complement(31303..32187)
                     /gene="isdE"
                     /locus_tag="VB649_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEP1669663.1"
                     /translation="MIKRCKGIGLALMAFFLVACVNQHPKTAKESEQQRIVATSVAVV
                     DICDRLNLDLVGVCDSKLYTLPKRYDAVKRVGLPMNPDIELIASLKPTWILSPNSLQE
                     DLEPKYQKLDTEYGFLNLRSVEGMYQSIDDLGNLFQRQQEAKELRQQYQDYYRAFQAK
                     RKGKKKPKVLILMGLPGSYLVATNQSYVGNLLDLAGGENVYQSDEKEFLSANPEDMLA
                     KEPDLILRTAHAIPDKVKVMFDKEFAENDIWKHFTAVKEGKVYDLDNTLFGMSAKLNY
                     PEALDTLTQLFDHVGDHS"
     gene            complement(32171..33046)
                     /locus_tag="VB649_000697"
     CDS             complement(32171..33046)
                     /locus_tag="VB649_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEP1669664.1"
                     /translation="MTKVVIKQLLQVIVVFMISLSTMTGVVYADKGQIYGCIIQRNYR
                     HPISGQIEDSGGEHSFDIGQGMVEGTVYSDAMLEVSDAGKIVLTFRMSLADYSGNYQF
                     WIQPGGTGSFQAVDYNITQKGTDTNGTTLDIAISLPTVNSIIRGSMFVEPMGREVVFY
                     LSASELIQKYSGNMLAQLVTETDNSQNQEVKDSQKPVDTKLGESQDESHTGAMITQNK
                     PKANSSNNKSLSDKKILPSKMGLTTSLELKKEDKFRSKKDLSIMIYYFPTFFLMLGGF
                     AVWVWKKRKKNDKTM"
     gene            complement(33243..37070)
                     /gene="shr"
                     /locus_tag="VB649_000698"
     CDS             complement(33243..37070)
                     /gene="shr"
                     /locus_tag="VB649_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein Shr"
                     /protein_id="HEP1669665.1"
                     /translation="MKKISKCAFVAISALVLIQATQTVKSQEPLVQSQLVTTVALTQD
                     NRLLVEEIGPYASQSAGKEYYKHIEKVIVDNDVYEKSLEGERTFDINYQGIKINANLI
                     KDGKHELTIVNKKDGDILITFIKKGDKVTFISAQKLGTTDHQDSLKKDVLSDKPVPQN
                     QGTQKVVKSGKNTANLSLITKLSQEDGAILFPEIDRYSDNKQIKALTQQITKVTVNGT
                     VYKDLISDSVKDTNGWVSNMTGLHLGTKAFKDGENTIVISSTGFEDVTITVTKKDGQI
                     HFVSAKQKQHVTAEDRQSTKLDVTTLEKAIKEADAIIAKESNKDAVKDLAEKLQVIKD
                     SYKEIKDSKLLADTHRLLKDTIESYQAGEVSINNLTEGTYTLNFKANKENSEESSMLQ
                     GAFDKRAKLVVKADGTMEISMLNTALGQFLIDFSIESKGTYPAAVRKQVGQKDINGSY
                     IRSEFTMPIDDLDKLHKGAVLVSAMGGQESDLNHYDKYTKLDMTFSKTVTKGWSGYQV
                     ETDDKEKGVGTERLEKVLVKLGKDLDGDGKLSKTELEQIRGELRLDHYELTDISLLKY
                     AKNITELHLDGNQITEIPKELFSQMKQLRFLNLRSNHLTYLDKDTFKRNAQLRELYLS
                     SNFIHSLEGGLFQSLHHLEQLDLSKNRIGRLCDNPFEGLSRLTSLGFAENSLEEIPEK
                     ALEPLTSLNFIDLSQNNLALLPKTIEKLRALSTIVASRNHITRIDNISFKNLPKLSVL
                     DLSTNEISNLPNGIFKQNNQLTKLDFFNNLLTQVEESVFPDVETLNLDVKFNQIKSVS
                     PKVRALIGQHKLTPQKHIAKLEASLDGEKIKYHQAFSLLDLYYWEQKTNSAIDKELVS
                     IEEYQQLLQEKGSDTVSLLNDMQVDWSIVIQLQKKASNGQYVTVDEKLLSNDPKDDLT
                     GEFSLKDPGTYRIRKALITKKFATQKEHIYLTSNDILVAKGPHLHQKDLVEKGLRALN
                     QKQLRDGIYYLNASMLKTDLASESMSNKAINHRVTLVVKKGISYLEVEFRGIKVGKML
                     GYLGELSYFVDGYQRDLAGKPVGRTKKAEVVSYFTDVTGLPLADRYGKNYPKVLRMKL
                     IEQAKKDGLVPLQVFVPIMDAISKGSGLQTVFMRLDWASLTTEKAKVVKETNNPQENS
                     HLTSTDQLKGPQNRQQEKTPTSPPSEATGIANLTDLLAKKATGQSTQETSKTDDTDKA
                     EKLKQLVRDHQTSIEGKTAKDTKTKKSDKKHRSNQQSNGEESSSRYHLIAGLSSFMIV
                     ALGFIIGRKTLFK"
     gene            complement(37560..39071)
                     /locus_tag="VB649_000699"
     CDS             complement(37560..39071)
                     /locus_tag="VB649_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP1669666.1"
                     /translation="MNKNKLLRVAMLLSLLAPTAESMTVLAQDVMLETHKATTNETSD
                     SSSKEENNKNAAPTTSDKTDQGPLDASAETNSNSLVNADDKKRSDSSQSAVGSSDNKA
                     EAENQVDDKSTDHSKPTDQPKPTDQPKPSPSKVDTAPASSLSRQLPEVRTPIQSLSPY
                     VSDLDLSEIDIPSVNTYAAYVEHWSGKNAYTHHLLSRRYGIKADQIDSYLKSTGIAYD
                     STRINGEKLLQWEKKSGLDVRAIVAIAMSESSLGTQGIATLLGANMFGYAAFDLDPTQ
                     ASKFNDDSAIVKMTQDTIIKNKNSNFALQDLKAAKFSRGQLNFASDGGVYFTDTTGSG
                     KRRAQIMEDLDKWIDDHGGTPAIPAELKVQSSASFASVPAGYKLSKSYDVLGYQASSY
                     AWGQCTWYVYNRAKELGYQFDPFMGNGGDWKYKAGYALSKTPKVGYAISFAPGQAGAD
                     GTYGHVSIVEDVRKDGSILISESNCIGLGKISYRTFTAQQAEQLTYVIGKSKN"
     gene            complement(39158..40258)
                     /locus_tag="VB649_000700"
     CDS             complement(39158..40258)
                     /locus_tag="VB649_000700"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEP1669667.1"
                     /translation="MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAY
                     GHGAVQVSKALLPQVDGYCVSNLDEALQLRKAGIDKEILILGVLLPNELELAVANAIT
                     VTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVE
                     GIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVR
                     LGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVG
                     TVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLPKAYPLGTKVTLIGSNQ
                     QKNISTTDIANYRNTINYEVLCLLSDRIPRIY"
     gene            complement(40255..40611)
                     /locus_tag="VB649_000701"
     CDS             complement(40255..40611)
                     /locus_tag="VB649_000701"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEP1669668.1"
                     /translation="MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYK
                     RRLSYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISIS
                     HSGNYVQASVILEDKK"
     gene            complement(40727..43246)
                     /gene="secA"
                     /locus_tag="VB649_000702"
     CDS             complement(40727..43246)
                     /gene="secA"
                     /locus_tag="VB649_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEP1669669.1"
                     /translation="MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGK
                     TLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRT
                     GEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSERIKAFLDRMKLDE
                     EDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHARSNRKDAIDAIVTFARTSLVPEESISAKELRGLKDD
                     QIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAP
                     QNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS"
     gene            complement(43380..44333)
                     /gene="manA"
                     /locus_tag="VB649_000703"
     CDS             complement(43380..44333)
                     /gene="manA"
                     /locus_tag="VB649_000703"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEP1669670.1"
                     /translation="MSEPLFLKSTMHDRIWGGTKLRDVFAYNIPSDTTGEYWAISAHP
                     NGVSTVTNGRYQGQPLNTLYVQEPALFGNPKEEVFPLLTKILDANDWLSVQVHPDDAY
                     GREHEGELGKTECWYIISAEEGSEIVYGHQAKSKEDLRAMIEAGAWDDLLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRKDVNGNLRDLHIEKSIDVLTI
                     GKPENSVPATMVLDNMVATTLVSTPFFTVYKWVTSQMVDMKQAAPYLLVSVLKGQGKL
                     YVDQKAYELEKGMHFILPNDVKSWSFDGQLEMIVSHPNQLV"
     gene            complement(44428..45312)
                     /locus_tag="VB649_000704"
     CDS             complement(44428..45312)
                     /locus_tag="VB649_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP1669671.1"
                     /translation="MGKLYGSIEAGGTKFVCAVGDEEFTVVDKTQFPTTTPEETIAQT
                     IAYFKTFEADLAGMAIGSFGPIDIDPSSETYGYITTTPKSGWANVDLLGQLSAAFKIP
                     FDVTTDVNSSAYGEVLARPGVESLVYYTIGTGIGAGAIQHGHFIGGLGHTEAGHTYVM
                     PHPDDMAKGFLGVCPFHKGCLEGMAAGPSIEARTGVRGERLDQEADVWDIQAFYIAQA
                     ALQATMLYRPQVIVFGGGVMAQEHMVLRVHDKFTTLLSGYLPVPDLTDYIVTPAVADN
                     GSATLGNFALAKLAAQGK"
     gene            complement(45553..48084)
                     /locus_tag="VB649_000705"
     CDS             complement(45553..48084)
                     /locus_tag="VB649_000705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEP1669672.1"
                     /translation="MDKHLLVKRTLGCVCAATLMGAALATHHDSLNTVKAEEKTVQTG
                     KTDQQVGAKLVQEIREGKRGPLYAGYFRTWHDRASTGIDGKQQHPENTMAEVPKEVDI
                     LFVFHDHTASDSPFWSELKDSYVHKLHQQGTALVQTIGVNELNGRTGLSKDYPDTPEG
                     NKALAAAIVKAFVTDRGVDGLDIDIEHEFTNKRTPEEDARALNVFKEIAQLIGKNGSD
                     KSKLLIMDTTLSVENNPIFKGIAEDLDYLLRQYYGSQGGEAEVDTINSDWNQYQNYID
                     ASQFMIGFSFFEESASKGNLWFDVNEYDPNNPEKGKDIEGTRAKKYAEWQPSTGGLKA
                     GIFSYAIDRDGVAHVPSTYKNRTSTNLQRHEVDNISHTDYTVSRKLKTLMTEDKRYDV
                     IDQKDIPDPALREQIIQQVGQYKGDLERYNKTLVLTGDKIQNLKGLEKLSKLQKLELR
                     QLSNVKEITPELLPESMKKDAELVMVGMTGLEKLNLSGLNRQTLDGIDVNSITHLTSF
                     DISHNSLDLSEKSEDRKLLMTLMEQVSNHQKITVKNTAFENQKPKGYYPQTYDTKEGH
                     YDVDNAEHDILTDFVFGTVTKRNTFIGDEEAFAIYKEGAVDGRQYVSKDYTYEAFRKD
                     YKGYKVHLTASNLGETVTSKVTATTDETYLVDVSDGEKVVHHMKLNIGSGAIMMENLA
                     KGAKVIGTSGDFEQAKKIFDGEKSDRFFTWGQTNWIAFDLGEINLAKEWRLFNAETNT
                     EIKTDSSLNVAKGRLQILKDTTINLEKMDIKNRKEYLSNDENWTDVAQMDDAKAIFNS
                     KLSNVLSRYWRFCVDGGASSYYPQYTELQILGQRLSNDVANTLKD"
     gene            complement(48315..50198)
                     /locus_tag="VB649_000706"
     CDS             complement(48315..50198)
                     /locus_tag="VB649_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEP1669673.1"
                     /translation="MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEK
                     AEAIDKVRGAFFNSGQYQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKQGNIFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVF
                     HSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGALGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIA
                     YIWGYQDRETLPLPAVEVDQTADQPALAEETLYSPLNGTVVDLSAVSDPVFSSGAMGQ
                     GLAIKPDDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTVSMAGDGFESL
                     VAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVTNSADYQSVDILAQGHVLIGDQVA
                     LIK"
     gene            50440..51879
                     /locus_tag="VB649_000707"
     CDS             50440..51879
                     /locus_tag="VB649_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEP1669674.1"
                     /translation="MDLPQAIRYRPYKEWSSKDYQAITEKMAQSPWHSQFHVEPKTGL
                     LNDPNGFSYFNGRYHLFYQNWPYGAAHGLKQWVHMTSTDLVHFTETRSRLLPDHAHDS
                     HGAYSGSAYAIDDKLFLFYTGNVRDANWVRTPLQVGAWMDKQGNISKIPQVLIEQPDD
                     VTEHFRDPQLFSYQGQFYAIIGAQGLDGKGKIKLYKAVDNHVDNWRFITDLDFDDSGT
                     EYMIECPNLVFVDDKPVLIFSPQGLAKADLDYQNIYPNTYKIFESFNPETGQLLGGGA
                     LQNLDFGFEAYATQAFSSPDGRVLAVSWIGLPDIDYPTDRYDYQGALSLVKELRIKDG
                     ILYQTPVSALQNLRGPAELFHNKIDSSNCYELELTIPGQKKLDLLLFADQKGNGLRLK
                     VDTTKGQLSIDRSRAGVQYAQDYGTVRSCQISQGHVTLNVYVDNSILEIFINQGQKVL
                     TSRVFPTQGQTGIQVVEGQAFGHYYEMRY"
     gene            51884..52849
                     /locus_tag="VB649_000708"
     CDS             51884..52849
                     /locus_tag="VB649_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP1669675.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMREL
                     GYKPNNLARSLQGKSTQLIGLIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNP
                     VKEREYLEMLAANQVDGIISSSHNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEG
                     GKLAAQTLQKHGCQNIVMITGNDNSDSPTGLRQLGFNYQLKRSAEIIKLPNNLSPVRR
                     EMEIKSILATRKPDGLFVSDDLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVP
                     QLATIRQPIDEIAKLSVEILIKKIKKEKTSKDYILPITLLPGASI"
     gene            complement(52990..53442)
                     /gene="nusB"
                     /locus_tag="VB649_000709"
     CDS             complement(52990..53442)
                     /gene="nusB"
                     /locus_tag="VB649_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEP1669676.1"
                     /translation="MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTG
                     EDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEI
                     KYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS"
     gene            complement(53435..53824)
                     /locus_tag="VB649_000710"
     CDS             complement(53435..53824)
                     /locus_tag="VB649_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP1669677.1"
                     /translation="MTTEHIGEIVISSRVLEVITGIATTQVEGVHSLHNKKMADSFNK
                     ASLGKGVYLQTQEDGSVTADIYVYLQYGVKVPTVSMAIQKAVKSAVYDMAEVTISAVN
                     IHVEGIVAEKTPKPDLKSLFDEDFLDD"
     gene            complement(53870..54427)
                     /gene="efp"
                     /locus_tag="VB649_000711"
     CDS             complement(53870..54427)
                     /gene="efp"
                     /locus_tag="VB649_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEP1669678.1"
                     /translation="MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEAGQKLIINTAEGTYVSRA"
     gene            complement(54523..54984)
                     /locus_tag="VB649_000712"
     CDS             complement(54523..54984)
                     /locus_tag="VB649_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEP1669679.1"
                     /translation="MTNRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEDGHCIRTVHAEMNALIQCAKEGISTDGTEIYVTHFPCINC
                     TKALLQAGITKITYKAHYRPHPFAIELMEKKGVAYVQHDVPQIVLGGDKEQ"
     gene            complement(55019..56092)
                     /locus_tag="VB649_000713"
     CDS             complement(55019..56092)
                     /locus_tag="VB649_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEP1669680.1"
                     /translation="MSGFLEQRLGHCLRQMAEKGLEALLVTHLTNSYYLTGFSGTAAT
                     VLITAKRRVLITDSRYTLLAKASVEGFDIIESRTPLKVVAELLEADQIDCLGFEDQVS
                     FSFYQAMQAELSGITLLAQSGFVEHLRLIKDTSEIDTIAKACSISDKAFEDALDFIKP
                     GTTTERDLANFLDFRMRQYGASGTSFDIIAASGYRSAMPHGRASDKVIQNKESLTMDF
                     GCYYNHYVSDMTRTIHIGQVTDEEREIYALVLAANKALIAKASAGMTYSDFDGIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHENPFLGKSEQLLQAGMVVTDEPGIYLDNKYGVRIE
                     DDLVITKTGCQVLTLAPKELIVL"
     gene            complement(56208..59036)
                     /gene="uvrA"
                     /locus_tag="VB649_000714"
     CDS             complement(56208..59036)
                     /gene="uvrA"
                     /locus_tag="VB649_000714"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEP1669681.1"
                     /translation="MQNKIIIHGAKAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPVVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKSLREGALAPWNPISSNYYPTMLEQAMASFGVDMDTP
                     FEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYT
                     RNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELEL
                     TENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GEFGGEITASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNL
                     QHLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHI
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     IVATGTPEEVAQVKESYTGHYLKVKLQQ"
BASE COUNT        17967 a        12611 c        10257 g        18238 t
ORIGIN      
        1 tttgacaaga gaaaaaaacg atatctataa aagaaaacgt tttctctaac tgttttgacg
       61 taaaaaaacg tataacttcg ggaaaattat cctgagatta tacgtttgac atctttaaat
      121 atcctctaag gcatctttca ctttatcaaa aaaacctttt ttctttggat gtaacatttt
      181 ttcaccactc gcttctgcaa atgcttgcaa ggcttccctt tgagcgtcat tgagtttggt
      241 tggggtcaca atattaacgg taacatgttg atccccttga cctccaccac ggagttttgg
      301 tgctcctttg cctttgaggc ggaaggtttt acctgtttgt gtcccagcag ggatagccat
      361 ctcaacatcg ccatgaaccg ttggaatttc aacagtatct cctaaggctg cttgagtaaa
      421 agaaatatct aagttgtagt aaatagtgga accattgcgt tcaaattgct tacttggtaa
      481 gacattcaaa ataacaaata aatcaccata aggtccgcca ttaaagccag cttctccttg
      541 accttgtaaa cggatttgct gaccagtctc tacaccagct ggaatcttaa cagacacttt
      601 atgagcttgc ttttcatgac cagtaccgtg acaggtttga cagggttctt taatttcctt
      661 accactacca tgacaaatat cgcaggtgac ttgtcgacgc atcataccaa gtggtgtttg
      721 ggtgtcaatt gtcattacac ctgaaccatg gcacttacga caagttactg gagcggtacc
      781 aggttttgca cctgagccta aacaagtgcc gcaggttgct tcgcgattat agctaacttc
      841 tttttcaaca ccaaatacag cctcttcaaa agataaatta acacgatatt gcaaatcgtc
      901 accttgacga ggggcatttg ggtttcggct tccaccgcca ccaaagaagc ttgagaagat
      961 atcttcaaaa ccaccaaagc cacctccgtc aaaaccacca aagccgcctg ctccgccacc
     1021 aaagccgcct tgagcacctg cagcgccgta ttgatcataa gcagcacgct tttgtgaatc
     1081 acttaaggtt tcgtaagctt cttgaacatc cttatacttt tgctccgctc cagcttcttt
     1141 attgatatct ggatgatatt tcttagacat ttttcgataa gcttttttga tatcgtcctg
     1201 agaagcgtcc ttagaaaccc ccagacgatc gtaatattct gtattgttca taatgtaaga
     1261 taccaagccg taaaacgact caatgaaaaa taggaaatcc gacaaagata ctctcgtatc
     1321 taggaggtat ttctcttttt tcgcagagtc gtaggcgtgt tcgaatccgc aaaagagtct
     1381 ttacacgctt tagcctgtgt tcgaataatc gaacttgtat tcctttctta aaatattttg
     1441 acgtcagcat ttttacattt tatttagcca aaaacagagg tttggtacaa cctctgaatt
     1501 cggatattaa tgttactaga taactaaatc attacttttc tgtaaattcg ccatctacaa
     1561 catcatcatt atttgctgaa tcattagctt gtgcaccttc tgcaccttgt gctgcttgtt
     1621 gagctgctgc agcttgctcg tacattttaa cagccaaagc ttgcgctttt tcatttaatg
     1681 cttcaagttt agctttcatg tcgtcaaggt tgccagattc ttgcgcagct tttaactcgt
     1741 caagagctga ttgcgctgca tcgcgttctg tatcaaagcc tttaccttca gtttctttga
     1801 ttgttttttc agtagcaaag atagcttggt caacttcgtt tttaaggtca acttcttctt
     1861 tacgtttcgc atcggcttcg gcattagctt cagcgtcttt catcatgcga tcaatttctt
     1921 cttcagaaag tccgtcgttt gatttgataa cgatgtgttg ttccttttgc gtaccaaggt
     1981 ctttagcttt tacagaaaca ataccgtttt tatcgatatc aaatgttact tcaatttgtg
     2041 ggattccacg aggtgcagct gggatatcag tcaattggaa gcgaccaaga gtcttgttat
     2101 ctgctgccat tgggcgttca ccttgaagaa catggatatc aacggctggt tggttgtctg
     2161 ctgctgttga gaagacttgt gatttagacg ttggaatagt ggtgttgcgg tcaatcaatt
     2221 tagtgaagac accacccatt gtttcaatac caagtgacaa tggtgttacg tcaagaagga
     2281 caacgtcttt cacatcccca gtgataacac caccttggat agcagcaccc atagcaacca
     2341 cttcatcagg gtttacagat ttatttggtt ctttaccagt ttcagctttt acagcttcga
     2401 caactgctgg gatacgagtt gatccaccaa caaggataac ttcatcaatt tctgacaatg
     2461 acaatcctgc atctgaaaga gcttgacgaa ctggagtttt cgtacgttca acaaggtcac
     2521 gagtgagatc gtcaaattta gcacgagata agctcatctc caagtgaaga ggaccagcag
     2581 aaccagcagt gatgaacggt aatgaaattt gtgtttgtgt cacacctgaa agatcttttt
     2641 tagctttttc agctgcatct ttcaagcgtt gaagtgccat cttatcttgt gataagtcaa
     2701 taccattttc tttcttaaat tcagccacta agaaatcaat aattttctgg tcaaagtcgt
     2761 caccaccaag tttgttatca cctgctgttg caagaacgtc gaagacacca tcacctaatt
     2821 caaggattga tacgtcaaat gtaccaccac caaggtcaaa aactaagatt ttttcatcct
     2881 tgtcagtctt gtccatacca taagcaagtg cagctgctgt tggttcgtta acgatacgtt
     2941 ctacttcaag acctgcaatt ttaccagcgt ctttagttgc ttgacgttgt gcatcgttga
     3001 aataagctgg aacagtaata actgcttttt ctactttttc tccaagatag tcttcagcat
     3061 aacctttaag gtattgaaga atcattgctg aaatttcttg aggagtatat tctttaccat
     3121 ttgcagaaac tttttcagaa gttcccattt tagatttaat agagattact gtttctgggt
     3181 ttgtcactgc ttggcgtttt gcagcatcac ccacgataat ttcaccattt ttgaatgata
     3241 ctactgaagg agttgtacga ttgccttctg ggttagcaat gatttttgat tcagtccctt
     3301 caagaactgc tactgctgag tttgttgtac ctaagtcaat accaataatt ttagacatgt
     3361 taatacctct tattttataa tactttatta ctttttattt caatttatct tagtaagcac
     3421 tcgaattatt ttacttccaa ttctaagcaa tcactatagt ttaatcagca agcgaaatag
     3481 cttctaactt gctatctagt ttactgtcat tacggacaaa aacgaaaact catttacctt
     3541 agttataaac aactaccatc gctggtctta gcagacgctc gtgcaattta tatccctttt
     3601 gaaagacttc tgcaatgcta tcggctggat gttcatcatc ggctgggagg gtctgaactg
     3661 ccatatgaaa gttgtggtca aatgagtcga cttctacttc ttctacgcct tcttccttta
     3721 gtgcttgaat aaggctatca cgagtcattt ctaaaccttt tttaacatca tctgtcaacc
     3781 cttcaacagc caaggcacgt tctagattgt caagcgatgg taagattgct tttgccagat
     3841 cctgagaacg atagcgttga agttgttgac gttcttcact agagcgacgc tgtatattct
     3901 gcatttctgc atgagctcgc aagtatttat tttcaaactc atcagcacgt tcgtttgcaa
     3961 gttctaactc tgatttttca ggagtttctt caataacttc ctcaactgtc tcttcagttt
     4021 cagtggcttc cacttcttct tgtaaatcgt cttttttaat ttcttctgac actgagtgcc
     4081 tccttttaca taacttattg aatactgcca ttatcagtga acttcataat ggttagaatt
     4141 taggtatcga taataatcac ctaatttagc agccaatacc tttccaataa tgtttaccaa
     4201 actaacagac ctacgataat ccatatcaat aggaccaatc aaactcagga gtccaaaccc
     4261 acggtaagga atcaaaaatt tgtgagttaa aactgacaca tctgcaagtg cggcttcttg
     4321 actatctgcc acttggacag aagccatctc accttctttc agactttgcc tcaaagaaat
     4381 tgctacttgc tgttcattat ccaaaaactg atacgttgat agatctgaat acgttaaaga
     4441 atttaccttg ccagctacaa ataccgtttc caaaaacagc tctgaaaaaa cataatcaaa
     4501 tagttgtaaa acattatccg tagtcacaaa atacttttga acgatctgag gaatttctgt
     4561 cctcaactta taatgaatat ctatgacact actatccagc aagcgctcct ctacgatagc
     4621 tttaaatgct atcaagtcac gtgtcaaaaa gtttcttgga atagcaaact gcactgtcac
     4681 tggcttagat tcatctaaag tcatgactgc tagagcatca tggttgctaa gctgaacaac
     4741 atcaaaccct gttaaacgtt gacgagctgg ctccacatct aaaataacgg atgtatagcc
     4801 cgtcatctcc gataaaatgt gactagcttt ttgaagcatg tcttctaatt tgaatgcttc
     4861 aaaatcaaaa gcttttatga catgataaat atcttgctca tcaatactat ctagtctaag
     4921 ggagtgctct acaaaatact taaaaccagc tggacttggc atccgtccac tagaagtgtg
     4981 cgctttttcc aacaatccca acttctctag ttttgccata tcattacgaa tagtggcgct
     5041 actagaatca atcgttctct gtaaagcttt agaccctact ggttcatgag tttgtgtaaa
     5101 tagctcaacg attaaattca aaatatcatt ttgacgttgt gtaatcacaa accaaccact
     5161 ccctttcgtt tagcactcta tttagtagac tgctaattta taattctatt atactcttta
     5221 tgagagacat gtcaagaaaa aaactcaaaa aaattagcac tcttttataa agagtgctaa
     5281 tttcagtcat agtttgttaa atcgttactt tcaatgacct gaatcagtcg cctagcatag
     5341 gttttatcag tataatgcaa atacttttgt aaacttttag ctggtgcttt ataccctttt
     5401 tctgtagcaa gattacgata caaacgctta tcgacttctt tgccctgccg aagcattcgt
     5461 aaataatctc taattgcact agcgtcatct ttataaatag catatctcac gttttggttg
     5521 gtttgtttag gggactttag ggtaatggcc gcttgtcctg gagttgcttt cttgctaaaa
     5581 agattatgat acttagacgc tagtaatgtt tttccatcat gggtttccaa aagaatttga
     5641 gcaatcaaaa tagatggtct aatgccataa tattttgcca atggtttaac ttctttaccc
     5701 atttttgtaa taaattgttt ttggctgtag ttcaccctta cttctttatc tgcactagct
     5761 atcctttggc tactcagtaa gggacaaaca atcagcaata aaaaacaagc tagaagcgtt
     5821 aaaaaatacg gaaactttag tcgttttctc atcgtttctc ctttaaagca gcaatgtact
     5881 cttccaacgt taggttgtgc tgaaccatat aacgagcaga cgccttgcct acatagcggt
     5941 aatgccaatc ctcataatca acccctgtac tagtcttttt tccttctgga aagcgcaaga
     6001 caaacccata atcaggtgca attttttgaa ctgctttagc tactgatgga tcactggcat
     6061 ttaaagtatc gacagtgctc atgtcaatag caagaccagt gtgatgttca ctagcccctg
     6121 gcggctgtga ataggtttgc accaaagcct ccgcagcttc ttgtgtcaat gttggatcgt
     6181 tagccatctc ttttttaata gaagattggt aaagctctgt ttggtagtct acggaacggt
     6241 acccagagat aagatgttct tgcgagtcga tagcttgtgc tgctgctaaa aagtcactag
     6301 tggcttgctc aatgcgttta tccacagaaa taccattaat gtcagctaat tcaggactca
     6361 tttcttttgt aatgtgatcg cggtttacta aaaccaactc ccaatcttca acagatacct
     6421 taggtaaagc tcgtaaacgg tccgtttttt tgatatcttt ttgttggatt tcttttttat
     6481 tcaactgagt tggtgttact gactcttctg gttttataaa gaggtaaagc cctcctaaaa
     6541 aaacaataac aattagcaat tgcactaaat agtttaacga attatatttc atctgaccgt
     6601 tcttctatta tttcacgacc gcggtagcgg taactcatat ctccaatagt ctttatcgta
     6661 aattggccat catcaaattc aacaactgta acgctcccat tatcaatata ctgtttgtct
     6721 cgatctggat caatcaacca cagaaacgtt ccaattgtca taccatggct aaccacaaga
     6781 gcatttccgc cgccagcatt ttgaatggac aaggcaatag cttcaaaccc ctcccaaatg
     6841 cgcttacgaa gaacttccca tggttctgcc caattagcgg tatctacttc cacgatgctt
     6901 tctgccagtt cagaataggg aacatcacgt aggttatcac gattttcaaa ggcttttgtt
     6961 cttggaagga cacctagaaa taattctgaa tcataagtcc cttctagact cccaaaacac
     7021 cactcacgaa tacgattatc tttagtataa ggcaaaaatt cgttttctga ttctcttaaa
     7081 ataatttcta ttgtctgcat ggttcgacct gaatcacttg aaaacgcagc cttaaatggt
     7141 atagttgcat cttttaaacc taggccaagt tctcgaatac cttcttctcc tttttttgta
     7201 agaggtgtgt cactccaacc ctgagcgcga ccaatggtat taaacatcgt ttttccatgt
     7261 ctggcaatat acaaccttgt ttttgtcatt tcaacctcct aaactgtctt attaattatt
     7321 atagcattta aagaaaacac ttgcaaaaca cttcctgatg gctatttgag atcaaataga
     7381 ccactgactt attgtctatt ttattaaaaa caatgctatt gctacaattc aaatcatcac
     7441 ataaatttcc aaacaattac atttgtgtgt ttcgctcaaa tatatataac aacagaccca
     7501 cactacaact aaactgacgt tacaaaatga tgtcaaaaca gtaacaaaat ctaactattt
     7561 gtcaagaaaa cgatattaaa ttttcacaca actatcttat aatgaggatg caaccaataa
     7621 aaagataaga cattttatgt tgcaaaaaag gctgcttgga aacttccatg cagccttttt
     7681 ttaatacctt tttccaaaaa tagctgaaac aagtacaatt acaattgctg ctcccaaaat
     7741 ggacgggaaa atagccatac ctgccaactg aattccccaa tccccaaaaa gcctttgccc
     7801 aacagctgac cctatgagac ctgcgataat attagtaaaa caacccatgg actggctttt
     7861 ttcagtcatt ttacctgcta tcatgccgat aaaggcacct acaattaaag accatatcat
     7921 cgttaacacc tcctttcttg taaaatcctt ttagaagaac tgctatccat taaatattct
     7981 taactttagt tgattccttt accttcttct ttagtaagtg tttccgtgcc tgagtaaaat
     8041 agaaaaaaca attccttcta ttaagatgga tagaccgaga acgactagaa gtcttcacac
     8101 actaaataac ttaacaaact ttatcacaca gctaatcgct aataatagtg tagacaaacg
     8161 tgatggttca ttaaatacac gtcagaaact cctgaaggtt ctaaagcaat acctgtcagt
     8221 cttattttag catagatgat ggtcttttta taggcggtca ctaacatgac atacaaaaag
     8281 gcagcctgtg aaagaccgac cgcctttttt ttcagagaca aaatacttta acttattgct
     8341 atcagcaact atcaatctcg caatttttgc aattcttgtg ccaataattg ttgagcgact
     8401 tgtggattag cttgaccttt ggttgccttc atcaagaagc ctgtgaaagc cttatcagca
     8461 ttacgtttgc ctgatttgaa atcagccact gcagcttcat tatcagcaaa gacttggtga
     8521 ataattggta ccaaaacagc gggatcagaa atctgaacaa gtcctgcctt ttcgacgtag
     8581 gcgcgagctg agccaccatt tttagccaaa tgcacaaaga ccttcttagc cattttagaa
     8641 gagattgtac catcagcaat gatagcaatc atctccacca aattttctgg tatcagagcg
     8701 atttcttcaa tggttttgcc ttctgcattt aagaattggg caacttctcc ttgcaaccag
     8761 ttagagactt gcttggcatc gccaccaaga cttactgcag tttcaaagaa atctgacaag
     8821 gctttggtag ctgttagctg gctagcatca taagctgaga ggccaagttc ctcttcgtat
     8881 ttagcacgac gttgagctgg gaattgaggt aattgagcac gcatctcgtc aatccaagca
     8941 tcatcaattt catataaggg taggtctggt tctgggaaat aacgatagtc cgctgcccct
     9001 tctttgaccc gcatcaaaat agtcccctta ttcgcttcgt catagcggcg tgtttcttgg
     9061 cgaatcaccc cacctgaacg caagagtttg gcttgacgtt ccacttcaaa ttcaagccct
     9121 ttacggacat ttgagaagga attcaagttt ttcaattcgg tctttgttcc aaattgttct
     9181 tgcccgtaag gacgaaggga aatattggca tccacccgca tagagccttc ttccatcttg
     9241 acatcagaaa tacccgtata ctggatgatt tctttcagag ctgtcaaata agcataggct
     9301 tcttcaggag aacgcatgtc ggcttctgac acaatctcaa tcaaaggaac tccttggcgg
     9361 ttaaggtcca cataagaata accatctgtg ccatgagtgt ttttaccagc atcttcttcc
     9421 aagtgtgcgc gttcaatacg aattttcttg gttgaaccgt cttccaattt aatctcaatc
     9481 catccgttgt agccaatcgg ctcgtcaaac tgtgaaattt gataagcttt aggattatct
     9541 gggtagaaat aatttttgcg gtcgaaatgc atctctttat ggatgtccat attgagggca
     9601 agcgcagctt ttatgcccgc atcaataacg cctttgttca tgactggtaa gacccctgga
     9661 aaagaccaat caatcacatt cgtgttggca tttgggtcct caccaaagtg agctgacgaa
     9721 ggtgagaaaa ttttggaatt ggtatttaat tccacatgga cttcaagccc aataatggtt
     9781 tcaaaattca ttacttgtca cctccaaaaa taatcggttg ttgcttgtga taatctgtca
     9841 ccgcttcaaa ggctgctgcc gcttgataga tggtttcttc agcgtatttc ggaccaatta
     9901 attgaagccc tactggcaag ccatcgacga atcctgctgg aatggaaatt cctggcagac
     9961 cagccaagtt aactggaatg gtcaataagt cggccaaata catggcaaca ggatcgtggt
    10021 tgagtgtgtc taagccaaaa gcaaccgtcg gtgttgttgg gcctaaaata agatcataat
    10081 ccgcaaagac cttgtcaaaa tcttcaataa tcaaggtacg cacttgaccg gcctttttga
    10141 aataagcgtc ataataacct gatgacaaac taaaggtccc aagcatgata cgacgtttaa
    10201 cctcatcacc aaagccttgg ctacgagtgt taacatagat ttcatccaag tttttagcat
    10261 cgtcagcacg gaatccataa cgaatgccat caaaacgttg taagtttgag gacgcttctg
    10321 acgaagcaat aatgtaatag acagccacac catatttgct atgtggaaga ctaacttcct
    10381 caacagtagc tcctaaggct tcaaattgtt tagctgccgc aagaaccgtt tccttaatct
    10441 caggatcaat cccttcgcca agatactctt taggaagggc aatcttcatg cctttaatgt
    10501 cacgaccaat cttagatgtg tagtctgcaa tgcggacagg cgctgaagtg gcatccttga
    10561 catcgctact tgcaatcaca tttaataatt gggcgttttc tttaactgtc ggagcaaaag
    10621 gtccaatctg atcaagtgaa cttccaaaag caatgagacc atagcgagaa acagtgccat
    10681 aggttggttt caaaccgaca acaccattaa atgcagctgg ctgccgaata gaaccaccag
    10741 tgtctgaacc gagagataaa cggacttgtc ctgaagcgac tgctgttgcc gaaccacctg
    10801 atgagccacc aggtactttt gtgtggtccc aagcattttt cgttttcttg aaataagagg
    10861 tttctgttga accacccatg gcaaattcat ccatgttggt ttttccaatg acaatcatgt
    10921 ctttagcgta ggcatttgct actgatgtgg catcaaaaat cggctcgtag ttatacaaca
    10981 tttttgaagc ggctgtggtt aggatgccct tggttgagat attatcctta acagctagtg
    11041 gaatacccga catgaggtta tcagcatcaa tacctttggc atcaattgcc gcagcttgtt
    11101 taagagcagc ttcttctgaa acagtgataa acgacccgac agcctcctca cgagacttga
    11161 tgtcttcaag tgttttttga gtcaattcgg ttgcagaaat ctccttagct acaaggaggt
    11221 catgcaactc ttcaatggtt ttatgattaa aaggcattag gcatctcctc cgtcatccaa
    11281 aatagcaggt accttgataa agtgattttc tttttcagga acatttttaa agagcaaggc
    11341 acggtctgtt ccttcttcag cgacatcttg acgcatcaca tttttcttat ctgccatggt
    11401 tgttgtaatg gcaacacctt cggtatcaac ttcgttcagc aattcaacca tgtcaacgat
    11461 tttagatagg gtcgttgcaa aggttgttgt ctcactttct gagaatgata attttgatag
    11521 cttcgcgaca tggcgaactt cttcttcaga aattttcatg atttctccca tccaagatga
    11581 caagaagtat tccagttcca aagaacagct ctgctattct ctaaaggtag cggaaaaact
    11641 cctcacatca tttttacata gtctcaatta ttatatcaca attgttccca tttaccatag
    11701 gtgactaatg caattctaga aagctataca gcaaaaaact tcctgactaa ggtcagaaaa
    11761 ccttagtcag gaagtgtgac aaactaaact ctatttgtct tgggtaagac tgtggcctga
    11821 agctttgatg gcagcctgag cagccgccaa gcgagtaagc ggcactctaa atggcgaaca
    11881 agaaacgtag gtcaggcctt ggctgtggca aaaggcaatg gaagcaggat cgccaccatg
    11941 ttccccacaa ataccaagtt tcaagtcagg cttaaccgaa cgggctaatg aaacggcggt
    12001 actaaagaga cggccaatcc ctttctgatc aaaggtctgg aacggctcct tatcaaaaat
    12061 acccctgtca acgtattctt ccaagcattt tcctacaaca tcacagaaaa agtaacgttc
    12121 tttcaagtcg gtaatatgtt tacgaaggta ataaaagggt gctttattct aatttaccaa
    12181 atcctcaacg attgtgacaa catgtgatgt gataagccta agataaaaat ggtacagact
    12241 ctagcattca agagtttgaa gctttattta tattctaatg ctgaaaagac tagagtttgt
    12301 ctaatggctg tgagacgatc ctttaaacca tcaactcaaa tcatttctca aacagctaaa
    12361 atcctgtctt cttcaaaaaa acatgtgttc tatctgacac agtccaaagt ttagttgcct
    12421 tttagacagc acaagaatca tcaggactaa ttctgaccag catgtcacat acctcatcta
    12481 cctaacccat acatacggta aaaccacata gagcaatgat tacggttccc aaactcttag
    12541 tcactgaatc aatagtttgg taggctcttt tagtaatcgt taataagctt agcaccaaga
    12601 acctgctcaa agtgagccaa agaccactca taagattctt ttgtaaggct agcgacagct
    12661 gatttaacaa tctctaattg ataaccaaga tgataagcgt caatagcagt atgtaagaca
    12721 cagatatcag ataaaactcc tgttaacact aattgagtga tacctctttc tcgtagtcta
    12781 atatctaaat cagtccccga aaaagctgaa taataacgct tatcaatcca aaaaactctg
    12841 ggatgttgct tcatatgact gtaaacttca gctagtggac cataaagatg gcgtccagta
    12901 gttcctttga tattatgtgc tgcaaatagc ttactctcag gatgccaagg atcattttga
    12961 tcatgacaat caatagcaaa aaaaatatag tctccttgat caaatgccgt tttagttacc
    13021 tctgctattt tagtggcaat agcctgagca gatttacctg cacttaattt accatcatct
    13081 gctacaaaat catttgtgta atcaattgaa atcaatgctc tcatcactat ctcctaaaca
    13141 gggaaacctc tccccttatc tcttatatat ggcattgtat cagtttttat tacaggtatc
    13201 aagacatcta tttgcatcta ccattaacag caaaaaacat ctcttttcaa gagatgttgt
    13261 ctttttctat ttaaaattct tttaatttag caaaaatacc ttcgttgata actttgaggt
    13321 atgtcccttt cataccaaga gaacgacttt caataatccc tgcactttct agtttacgca
    13381 gagcattgac aataacagaa cgggtaatac caatacgatc agcaataaca gaagctgtca
    13441 atcgtccttc gttaccatct aactctccaa gaattgctgc aacagctttc atttctgaat
    13501 aagaaagcgt attaattgcc atgttgaccg ctgtttgttt acggatggtg tcttctaagt
    13561 tttctgtctg aagatttaat agttgaatcc ccacaacagt acttgagatc tcaaccaaaa
    13621 tcaaatcatc atcactaaac tcattgtcat tacgccagat aatgagtgat ccaaggcgca
    13681 tccctccacc ataaatcggc gcaatagtcg ttagacctcc tggataagtg tctttagact
    13741 caacagggaa tatagtcaat tcattttcga cagaaaggtt agcttctgta tcgtaaactc
    13801 ggctagcagc ctttacataa gtatctggaa attgtttagc ttcaaaaaat tcctcaacac
    13861 gatcagtgtt agttttatat ttcatggcat aaccaagcaa tgtgccgccg ccattgataa
    13921 tacaagcatt gcagtcaatg atatctgcta ggcgagatgc cattgtgtta tacggtaatt
    13981 ctgtttctag gctatctacg gaacgctgca aaatagatgt gattttacga gttttttcta
    14041 ataagttagg catttttttc cttttccttt gaattatttg cgctttcatt ataacaaagc
    14101 taactcgctt ttgcaaggaa ttatcagaaa attttctatt cttactacaa ttccaactat
    14161 taatgcctta ttatcacttc atttaaagga gataagcact agcttgttag agcatagggt
    14221 cacattcttt taagaaacgc tatttttatt aatcaaagat gagcattgca ttaacgtcta
    14281 tactggtata agacacgtgt aatcttttct tggacatctt ctaattcttc tacacttggt
    14341 aggtaaacaa tacggaagtg atctggatct ttccagttaa aaccacgtcc atgtaccaac
    14401 atcacttttt cttgctttaa taactgtaag acaaattctt catcatcatc aatacgatac
    14461 atctgacgat caattttcgg aaataaataa agacctgctt caggtttaac tgccgataag
    14521 ccagggatag cattaatagc ttcataaata aaattacgtt gctcaaaaat acgccctcct
    14581 ggcagtaaca gtgcatcaac tgattgatgg cctcctaagg aagtttgaac aacttgttgg
    14641 gctaaaacat tggagcataa ccgcatattg gcaagcatgt tcaacccttc aatataacct
    14701 ttaacatggt ctttaggacc tgataagacc atccatccaa cacgaaaacc agcaatacga
    14761 tgagatttgg aaaggccatt catagataca caaaaaacat caggtgccaa acttgcaata
    14821 gcaatatgct ctttaccatc catcaccaaa cgatcataga tttcatcggc aaaaataatc
    14881 agctggtgtt ctcttgccaa agcaacgatg tcttctaaaa tctccttagg ataaagggct
    14941 cctgttgggt tattaggatt gatgaccaca atagctttgg tgcgactcgt gatttttgat
    15001 ttgatatcag caatatcagg ataccaacca gcttcttcat cacaaagata atggactgct
    15061 tttcctccac caagactcac acaagccgtc cataaaggat aatccggcat tggtactaaa
    15121 acttcatcgc cattatctag caaagcttga agggacatgg atatcaactc tgacacgcca
    15181 tttcccaaat aaatatcttc aatgtcaaca tctgggaagc ccttgagttg gcaatactgc
    15241 atgatagcct tacgcgctga aaaaatccct ttactgtcag aatagccctc acttagcctc
    15301 gcgttgacaa ttaaatcacg aatcacttca tctggtgctt caaaaccaaa ggcagcagga
    15361 ttgccagtat ttaaacgcag aattttttca ccactcgcaa tcatgcgatt agcttcatcc
    15421 aaaacaggcc ctcgaatatc ataggcaaca tgttctaatt ttgatgattt ttcaataatt
    15481 ttcatagtct catacacctc gtattccata ttataaacca aaatacttaa aatagaaaga
    15541 atttatccat caaagcttag gacagctaat cgttttaaca caggtcttat gagacgataa
    15601 tacagtcttt agtttagcta aaataatgga tcgctttcaa aatgactcaa aaaagagtat
    15661 aatgaaaaaa agaataaaag ctattcttgt caaactgtta aaggaggaca gttctatgtc
    15721 actaaaatat aaacgtatcc tcgttgctat tgatggctct tatgagtctg aattagcttt
    15781 caataaaggc gttaacgtag cactacgtaa cgacgctacc ttactactag tacacgttat
    15841 tgacacccgt gccttgcaaa gcgtagctac ttttgatact tacatctatg aaaaattaga
    15901 acaagaagct aaggacgttt tagatgattt tgaaaaacaa gcacagatag caggaattac
    15961 aaacatcaaa caaattattg aatttggcaa tcccaaaaac ttactagctc acgatattcc
    16021 agatcgtgag aacgctgatt taattatggt aggagctact ggtcttaata cctttgaacg
    16081 cctccttatt ggctcatctt ctgagtacat tatgcgacac gctaagattg acttacttgt
    16141 agtccgagat agcactaaaa cactttagtc tattacaatt ttcaaacacc aaaaaacaag
    16201 cagcatctac aacgaaattg cttgtttttt tgtgctgagc taaggctagt caatatcttt
    16261 ttatttcttg atatttaaaa gagtaaacct ctatttatcg aatcgttgta gtgatttttg
    16321 taattgtttg tctaactctt tttttatggc tacttcaggt gcgtgacgct cttgccaata
    16381 gtcaggtttt tgaattttat gggtaacggg gtcaaagtgt gccttgccat ctggaaaaat
    16441 tttagccata tttgcttcat gtactgcttc aaatataggt tgtggatcta ctcccatcag
    16501 tacaaaagaa ccataagtaa aataaagcaa atccgctaag gcatcaactt gcccaatcag
    16561 gggcgtttca acatgttttt tagcttgtac cttattagct gcttggtcaa cagcaccatg
    16621 caaatcgaaa atagcctgtg taaattgttg ttggtctccc ttgcttgctg cgtaaagaaa
    16681 ctcaacaatt tcttctactt tgaagcctga cctataacca gcttctgaaa tggtatagct
    16741 acgcggtgtt tcaatagtat ctgagtccat cagacgatga aaatctttga ctttattaaa
    16801 attttcatca cggcttttaa agctcttctc tacatcaaaa tggatgagac cgtagtgagc
    16861 taaggctttg gaaatcccat cattattatt agagtcggta gtgaaatggg ctccatcttt
    16921 taccacagtt tcagcatttc ccatagcaat accgatacca actcctgata acatttcaag
    16981 gtcattatct gaatctccaa aagccatcac ttcagacaag tcaaatccaa acatctctcc
    17041 caaacgttca attcctttta tttttgattg atcaacagag atcagatcca aggaataagg
    17101 actacttctt gtaattttta tatgagggaa cttctcttgt attttcttag tttcagcttg
    17161 tgacgctacc agaacaacct gataaatagg ctcccgcata atagttacta aatttctgaa
    17221 actctgaggc ttgattcggc gaatcaaatg cttaaaacta ccctcaactg ttcttgccca
    17281 acttttgggc acaaaactac taataacttg tccaaatggg ctagtcccca tatcaataat
    17341 acgcgatcct gctaatccag aagctgttcc aagagaaatt tctcgctttt tttcgttggc
    17401 atagcgaatc actttgtaaa tcatcgactt tggcaattga ttctgatata agaccttatc
    17461 tcttgttaag atatattgcc cattgtaagt aacggcaaaa tctaatccaa aattttctag
    17521 aaaaggttgc acaaatcccg gtccacgacc agttgctaaa ccgaccataa tgccttgttt
    17581 tttgagttgt tggatggctt tttgcgttgt tttttggata tttttacgat cattgagaag
    17641 ggtcccatca atatcaaaaa agactgcttt tactgtcaaa accttctttt gcctcctgtg
    17701 tttatgatag aatagattat atcataaata aaaggaagtt tgacaatcaa atgaaaaaaa
    17761 tcctagtctt acacactggt ggaaccattt ctatgcaagc tgataactct ggtagggttg
    17821 ttccaaatca agataatcct atgacgaaaa tacatgctgc agcccaagat attcagctta
    17881 ccgttagtga ttttctaaat cttccgagtc ctcacatcac gcctcaccac atgttatcta
    17941 tttatcatca tattcaagaa agaactgatg tctttgatgg tatagtcatc acacatggaa
    18001 cagatacctt agaagaaaca gcttattttt tagataccat ggcattgcct actaatatac
    18061 ctgttgtcct aacaggtgct atgaggtctt ctaatgaagt tggtagtgat ggcatatata
    18121 attaccttac cgcacttaga gttgcaagta gtgataaagc taaagaaaaa ggggtacttg
    18181 ttgttatgaa cgatgaaatc catgctgcta aatatgttac taaaacacat acaaccaata
    18241 tttcaacttt ccaaacaccc acacacggac cgcttggtat catcatgaaa aatgacctac
    18301 tttttttcaa aactgctgaa cctcgtattc gttttgactt gagatgcatt tctggaacca
    18361 tccccattat caaagcatac gcaggtatgg gcgatggtag tatcttgagt ctattaactc
    18421 caggtagcat tcaaggtcta gttatcgaag ctctaggggc aggaaatgtc ccaccattgg
    18481 cagttgggga gatcgagcac ttaattactt taggtattcc tgtcgttctt gtttcccgtt
    18541 gtttcaatgg tatggcagaa cctgtctatg cttatgaagg tggtggtgcg atgctacaag
    18601 aagcaggtgt tatgtttgta aaagaattga atgctccaaa agcccgtcta aagttattaa
    18661 ttgctctcaa cgccggactt actggtcaag agctaaaaga ttatattgaa ggataatcta
    18721 gcttcctgta gaaatgtccc actaaaacat attagtggga catttctagt actttaagct
    18781 ttaaattagg acatctccta aatgtctata ataaacaact atgcttcaaa ctatgagatt
    18841 gtgcactcat aatcatttct ataacagttt gagaccagta ttcccataaa tccaactctt
    18901 agcaatcaga taccgggtaa acaagtcttt attttgtctc attaagtatg agcttactcg
    18961 aataataaca aaactacttg ctcatccttt tttagtaatg atgaagacga cctttttcta
    19021 agaacttctt tgtcttttaa aataaacaaa gcacatatta ccctttattt tagttctcgt
    19081 ttggaaaaaa gaaagacatt gcctaaaaga taacaaagag ttaaaccaaa ggccactaat
    19141 atgctagtac tagaaaggtg tttatcacca agagacaagg ataggtgttt aaacatcaaa
    19201 actgggctaa tatctaactt aaaaaaatgg tttgctaaag tagcagatac tttatcaaaa
    19261 agaaggacat aaagtatata agctgtgatt gactgataag ttttacgaag tatattaaac
    19321 aaaaattgac acaaagcaat aatagcaata taaaaaggca gttgtttaat catccgatct
    19381 atgactattc catagtatgc ttgaccagta aataaatgaa atgctaaagc actaagaaga
    19441 taagttaaac taataaataa aagagataag ccaaaactaa ctagcagttt atagattata
    19501 attaaagtac gattttgttg tttgaccaca acattattaa tcgtacggta gttatagtca
    19561 tcactaaaaa agatacgggc tggtgttaaa aagaaaagcg tcacaaaatc agtaataata
    19621 ttaatgattt gtatcatgat gacttggtta ggtgtcttgc gaaaactata ggctacacca
    19681 acagcaatga caacaagtag catacaagaa aatagagcta aacgctcttg acgtatgcga
    19741 aataaatctg ctttaagata ggaaatcata aaaacctctt tctaaattaa tggtgacgct
    19801 gcatctttac ctaacaaatc gaggtaataa tgttcaaagc tcacttgatg atgataaatg
    19861 tcaaaaatct caacaggcag atctagaaca attttgataa gctccattac tgataaagtt
    19921 ggttttatta gtagcatctg accatcagtc tcaactctaa gtcccaattc taaaagtcta
    19981 ttttttacca gctgatcatc gcttgtatga agggcaattt gtacttttac ttgagcttta
    20041 agctctgctt tgtccatact cttaataact ttgcctttat gcataatcac gtaacgatca
    20101 acaactaagt ctaattctga taaaatatga ctggaaatca aaatcgtaat accatagcaa
    20161 tctcttaggt tcaaaataat ctgacgcatt tctttgattc ctgctggatc aagaccatta
    20221 atgggttcat ctaagattaa aaattctgga aaatctagta tcgaaagacc aatagccaaa
    20281 cgttggcgca tccccaaaga ataatctttc acctttttct ttttgctcac tttttctaac
    20341 ccaataagtt ccaaaacctc atgtatgcgc tcttttgcat cagctaatct caattgcaac
    20401 gctgcatagt aaagattatc atgagctgtc atattgggat aaagtgtcgg tgactcaata
    20461 attgatccca ttcgataggg ttgtaactgt ttgatttgcc ctgaatcttt tccaattagg
    20521 ccagataaaa tacgcattaa cgttgtcttt ccagcaccat tttgacccac aaggccgcaa
    20581 atttctcctt tgtaaatatc aaaagagata tcacttaaaa cctgattttt accataggat
    20641 ttatttactt gctcaatact tagtaacatt gattgctgtg tcattttccg ctcctttttt
    20701 gtacttatcg attaatacaa tatcttacac ataataacat ctgtaaacgg ttgtgacaag
    20761 ttcttctttt tattaaaaaa atataaataa gaattttaat aatatgatta ttttagcaat
    20821 aaaaagttat actgaaaatg ggttaatact gcttcaaata gcagtctcat cgtaaagcat
    20881 aagtaaaaaa ggccagaaat agtgacctct ttatacttta taacagttta tctcaaaact
    20941 aactaaatat ttgtaaaaca acgacttgtt ttaagttaat cataaacttc tttttttcta
    21001 atattttgtg ctactaattg ccactgtttt tcatatatcc agttaggatc agaaacaatc
    21061 gctgcagaaa ctttgcgtgc ttcttctaaa ataggataat cctcaacgat atcagctact
    21121 tgaaattctg gaattccaga ctgacgagta ccaaagattt caccagaacc acgcattttt
    21181 aaatccgact cagccaaaac gaaaccatct gtcgtttctg tcatgattgt cattcgtttt
    21241 ttccccgaat ccgttttggg attagccact aaaacagcgt atgattgttt atgtccacga
    21301 ccaacacgcc cacgaagttg atgtaactga cttaatccaa aacgatcggc atccataata
    21361 atcatgatcg ttgcatttgg gacatttacc cctacttcaa taactgtggt ggatactaaa
    21421 atatgacttt ttttatcctt gaaatcttgc attatagcat ctttttcatc atttttcata
    21481 cgtccatgta caagagcaac cttagcaatt ccttcaaaat aagtagataa ttcagcatgc
    21541 aatgctactg cattctttaa atctaaagct tctgattctt caatcaacgg tgaaatgaca
    21601 tacacttgag catctttttg caattcacct tttacccatt ccaacacagt ccctagctgc
    21661 tcgtgtttca cccagcgtgt cataataggt ttacgaccgg caggtaattc atcaataaca
    21721 gaaacatcca tttctccaaa agctgtgatt gctagagttc ggggaattgg ggtggctgtc
    21781 atcattaaaa catcaggatt ttctcccttt tcacggaaaa ttctacgctg tttaacacca
    21841 aaacgatgtt gctcgtctgt aatgacaagc cccagtttgt ggtactgtac cgagtcttgg
    21901 ataagagcat gagttcctac aatcatatcc actgagccat ttgcaatagc tgctaaaacc
    21961 gtacgcttga cagcggcttt catacccgaa gttaatatag caattgataa atctggaaat
    22021 aactcttgca gactaatgta gtgttgttca gctaggattt ccgttggaac catcaaagcc
    22081 gattgaaaac ctgctgtata agctgcatac attgatagac cagcaatgac tgtctttcct
    22141 gatcctacat ctccttgcaa taaacgattc atatgagctc ccgatgacat atcagataat
    22201 atgtcatcta aagagcgctt ttgagcattt gttagaataa aaggtaaaga ggaaatcttt
    22261 gtctccatag catgtttact ataaagaata ggcaaaccat ttgtttcaga tctattttcg
    22321 gctttcaaaa cttgaaggtt catttgaaag taaaataatt cttcaaattt aatccgacgg
    22381 agcgcttgct tatactctgt gatatctttt gggaaatgca tagctaaaca agcctgacta
    22441 cgacccatca atcggtattt ttccaataaa gtagctggta aattttcctt caattccaaa
    22501 tgcgcatcga tttcaaaagc tgacttaata gctttaatca aagtagactg tgaaattccc
    22561 tgagctacgc gataaacagg ttgcatgtca tcttcaactt gagctaaaac cttcatccca
    22621 gtaatagccg atttagtggc atcccattta ccaaaaacag ctacctcttg accaagttct
    22681 attttatcag ctaaataggg ttgattaaaa aaactaacat ttaagacagc ttccccttga
    22741 cgcaatttga aacttaaacg gttacgttta aaaccataat attgtacatt agctggagta
    22801 acgactaagc ctgtaatgac tgctttttca ccatccacta aatcaaaaac agattttgat
    22861 ttaaaatctt catagcgaaa cggataataa agcagtaaat cttctactgt ataaatatct
    22921 aatttctgaa atttttctgc tgattttggt ccaaatccct ttaagttgga cataggagct
    22981 gttaatatca ttatcttttt cccttcacaa aaactcttgt cagattgaag acaaagtttg
    23041 tcgtgatact ttccttaggt ggtgcttacg gcagcgacgt tctttggaat tccatgcctt
    23101 tatttttgag cctgaggtct caaaaatccc gagtggcgtc aatctcgtat tgacgccact
    23161 cttttaccac agcaaaaagc atctgttttg gctcactttg tgtgtaaaaa tcggaaaccg
    23221 gatgtcaaat cagcagagct attcatgctt tttgagcata aaactggggt tgtctacgtt
    23281 ctgactcttg tatctattat acaagagttc ctatttattt tcagataaaa gccttttagt
    23341 acttttaaac agttctaggg ctcgttaagg tagcatttga taaatggtat cgcagacact
    23401 acttagaagt tcttcatcat gtgaaatgag gatgacaacc ttatgttggg tcttcagctg
    23461 catgagaaga ttagctaaag ccttcatttg taacaaatca agtccgctac ttggctcatc
    23521 aaaaattaag atatctttat cagccaaaag actagcggca atcatcactc tttgttgctc
    23581 acctcctgac aaactagctg gatgacgttc taaaagagtc gttaaagata accgctctat
    23641 tacttctgtc gtccgtggat gtcgttcatg gcccaagttg acttcctttg aaaccgattc
    23701 tgcaaatagt tgcaaagaaa cttcttgcaa gacaatacta gtctttgata aacgttgctt
    23761 ggcagataaa ggtatgcctt gaaacttaat agttgctttt ttatcgtcta agataccagc
    23821 tatataataa actaattgcg attttccaag cccgtttgat cctgtaatgc cagaaatact
    23881 tcctgcagca aaactaagct gttcaataca tctaagtatt ttgcttcccg ctctaactgt
    23941 tagatgctca atacacaggc tatcatctgg gcgataatgt tgactctcaa tcttaccagc
    24001 taacacaggt tttaggtcag acaagtctaa gcgacgtagt cccatatctt gccgttgttc
    24061 atctgtcaag gctagcaaat cttgtgttgt taacttatct gttaatctac catttttaaa
    24121 gtagaaaaag ttatctgcca aatccatcaa gtaatgtaag cgatgctcgg ctacaataat
    24181 ggtttttcct gctgctttta attgggtaag ataggcttta acagcagcta tgcctgcact
    24241 atctaagtta gcagttggtt catcaaaaag cataatatta gtaccttgca taatagccgt
    24301 tgcaatagca actctttgtt tttgccctcc tgacaatcca aacatatcct tgttaaggag
    24361 ctctgcaaaa gcaaaatctt ctgctaaagt ccaaagacgc ttcatgataa cctttgcatc
    24421 taaaccttga ttttcacagg gaaagaccag ttcgtgttgg acttcgcgat agaaaaactg
    24481 actggctgga ttttgaaaaa cagaggccac agatctagaa aatgtttcaa cactgtctct
    24541 gcctgcttgg caatcagcca catctagtct accttcatat tttccagcat aataatcagg
    24601 aattatgcca ttaagaagtt ttaaaaaggt agatttacct gaaccagaag gtccacacaa
    24661 aacaatgaat tgtccagagg caatttgaca agtcgatacc tgacaagctg gatttttttg
    24721 atcatgatag gtaaaaacaa gttgttctgc tgaaatcatt gaagtatcgt gatgattatg
    24781 ataacagtaa tccaaatctg caccccccaa tctttccatg ttaagtgtga gctaaagcat
    24841 tcactggtgc ctttgttgac tgctagtcct ttagttagac tagcgatagt tagttcttga
    24901 ctacttctta tcaaagataa aagcaatgga accattaaat actccaagta ttgtttaggt
    24961 ctgatcaaaa tagaccattt tgttaaaata atccccctga ttgttaaaga gcgatgaata
    25021 acacaacatt cttgtctaat cattggtatg aaacggcaca taacggctaa ggtcaatagc
    25081 cagacttctg ggaaatgcca tttgcgtaat ccatgaacca attcgtagat ggtagttgtc
    25141 ttaatagtaa ttaaacctgc tagtaaagaa gggaaaacta accttcctgc tattgagaca
    25201 aaactcaata agtgatcaag ataagaaggg aaaatagata gcgggattac agatagaccg
    25261 atcattaaca gataaacaac cgccaatttg aacgctagct ttttcttatt taaagcagac
    25321 aaaagtaata agagaaaaat aacaattata aattctaaaa agccatcaac acgaaaaaag
    25381 aagcaggcat tggcaagtac caacaaaagc agtttggtgc gaacatcaag cctcatgata
    25441 acaatcctga tttgataaaa tgtttcttta gtaaataatg tgcaaaagct gaccctaata
    25501 aggctcctgc aagaacaatt cctacaaacc aaataacatg ccctaaacta aaatcataca
    25561 taatgcgatt gacataggtc atacttttac cgcgggctaa caaactttca acataggcat
    25621 ctttcaacaa ccacatcagc aaaatagggc cactattgac aaaagcaaaa accatataag
    25681 ataggtcatt aaaaaacctt gacttgtatt ttcctaaaga agcaataata tccgctatta
    25741 aaccgaaaat aatgctggga aacatcgcgg caaaaaagtg accactaagg aagaaaaaac
    25801 ctcccatcat caatcctaat aatgttattg gcccaaatgt ttgcaattta gcaatcaaaa
    25861 gaaaataaat tgttcccccc agtaaagctg caaaggcagg ggcatataac atatttcctg
    25921 agcgatcaaa aaagatgtta ataaacgtgc ctagaccaac acaaataaag tagagcgcgg
    25981 caaatgcgcc tgttatcata atatctttta ttgttaactg tttcattttt tattcacctc
    26041 ttttaggaaa ccatttttta cgcaaaatag atgatcagca caagctaggg ttgatggcct
    26101 gtgagaaatt aagaagacca atccttgaca atgtgtttta attaaatcaa gcaagatagc
    26161 ttcatttaga gaatctaaat ttgacgtggg ttcatcaaaa atatagcaac tcgcgtcttt
    26221 caataaagct cgcatcaact ctaaacgttg accttctcca gctgaaaagt cagaaggact
    26281 cttgataatc gtatccaaac cttccttaca agctaacagt ctgtctttca taccacaagc
    26341 ctcagctaaa ttccaaatgg actcatctga aatatcttga cggccaaagg taagattttc
    26401 acggatagac tgttggaaaa gctgcgctgt ttgtggcaca taagcaatag tatcttgtaa
    26461 tttagcagca tttagtaagc aactattcct atcattaaga aaaatatctc ctgtcttcca
    26521 attataccat ttcataatta atttcaccaa agttgattta ccagatcctg attcgccttt
    26581 aatgccaata atcccctttt cttgaaaggt aactgataaa tccttaaaaa ccagctcttg
    26641 gcgctttgga taagcaaaac tgaggtcctc gaaagaaaca ctccttaaac gatctatctg
    26701 ttttgtgcct tcgtctacta tgacattttc gtctagaagg ttaaaaatat ttcgagccgc
    26761 attcatagca cgcttaaagc ctaatggcaa acgtcctagt tctaaaaaag gagaaaacga
    26821 agcagtgaaa gcaataaaag ttaataagcc tttatcaaat gataagctgt cacggcatat
    26881 cccatcaaaa accatataag aaaatgctaa gatcattaag ccaagccaga aaaaagtcaa
    26941 tgccatttgc aaaaattgag cttgcgctac gttacgatca agagcattta catgattact
    27001 tttttttatt aatcgttcaa attgctcgtc taatacctga aattgcaaaa gatctttgac
    27061 tgatcgtaaa ctctctaaaa aataagacag ataatctttt cgaccttcat tttggctttt
    27121 tagtaaaacc tgtaaaatat tagcaaaata aatgggtata acaatggcta aacaagcata
    27181 ggttgccaaa gctaataagg ctaactgcca actactttga caaaagtacc agaacattaa
    27241 acctgcagac aatattgctg tacaaatagg tgcgattgtg tgggcaaaaa aaacttctaa
    27301 tgcctcaata tcttctccaa tcattttaag caaataacca ctgtcttgac tatccaagca
    27361 agctggagaa agagctctta gtttcttaaa gatcaagttc ctaaaagctg ctaaactatg
    27421 aaaagcaaca aaatgaccaa aataatgctc tccataacga acaaaacctc ttaaaaaggc
    27481 tagagcaatc aaaagatata aagctaatat tggaatcact tcttgtctaa tagctagtag
    27541 tcctaaataa gctattccag ttggaatact taccgtgatg acaaaaccca taacagcaaa
    27601 gccaacagcc aagataatcc aaggtagcag agttttcatt agggttaata aacgccaaac
    27661 caggcttaag gtagatctgt taggtttagc cataaatact tgcctccagt cttgcttgag
    27721 tatcaactag gtgacgataa gttggttggt cccgataaag gtcgcaaggt ttgcctaaac
    27781 aagcaggctg ccctgtgttt aaaaagagta cttggttagc tcctttcaat cgagacatct
    27841 tatgagtaat cacaataact attgctgtct tagctaatct cgttattaaa ttgtcaataa
    27901 tacgttcatt ttctgcatct agactagatg ttgcctcatc aaagatataa agagacctct
    27961 tacttaatag agctcttgcg caaatcacct gttgcttttg gcctggtgat aacaggttac
    28021 cattttcacc aactattgtg tcaagaccat ctagtagcca gttgatgaag cttaacaaac
    28081 catgttgatc tatccaatct aagatttctt ttttagagag atttgctgct aaccttaaat
    28141 tatcgtaaat gctacggttc aataaggtag attggtccga tacataaaga acctgctggt
    28201 tgatagtttc ttgcgacaaa ttgtcactgt ctaaaccgtc aaataaaata tgcccagtcg
    28261 ttgcagactg gcgtttcaag aggagttgag ctagacttgt ttttccttgt cctgacaccc
    28321 ccgcgatagc tgttagttgg cccttcgtta atgtcatggt aaccccacta agcactgttt
    28381 ttttctcata agctaaagaa atattttgga tatcaatctg gttaaagttt attgctgttt
    28441 tactcttgtt atctttcctt gctggaatac tatccaagaa actaaagata cggtcagcca
    28501 ttttggtatt catcatgacc aagtgcatgc cataaccctg ctcacgaatc ggtgtaaaaa
    28561 attctgtagc aatcaagaga aaaaagagga aattaaaaaa agataactgg cctgttgcca
    28621 aagcttgaac ggctaaaaaa cctgacaaac caattcccag atacataact gcatccatat
    28681 aaccaactgc ttgtaactga aagccaagca aagacatggt agcctttcga aactgttctg
    28741 ccttacccga aaattcttgc tcgtaacgtt ctgttgcttg ataagaatac agtgtattaa
    28801 gaccttttaa gtcatccata aataaattac caacatccat ataagaagac caataatgac
    28861 tcataatttg cttagactgc ttttgcatag caacgattga aagtggaatc agaggcagaa
    28921 ctcctaaaaa gacaaggcct gccaatggat aaattaagaa gactagtatc ataatagttg
    28981 tgcagttcca cttggttctc atagacaaag acaaatagta accataataa gtatccaaac
    29041 tatcaattcc ctgtgaagcc aatgttaaaa tatcagcatc actggcatga gcatcaaatt
    29101 gcccatctaa atcaataaaa gcctcaaaga aagattgttt gagtgaatct ctagcaaatt
    29161 gtgaagcgat cccttgcagt tgcttgccta atatagcaag aacaaagcct accacattta
    29221 aaagtaggag taaacctgcc aagcgtccta aggcaatagc atgacccaaa ataaaggtcg
    29281 aaaacgtttt ggcaatgagg taaaaactga tcatcctcat cacaaattgt aaccaagata
    29341 aaaaggctga cacataaagc aaataccttt ttggtgcaat tcgttcacgt aatcgtttta
    29401 acagtctttt cctttttccc cttgatattg tatcttctgt ttccatcatc tgttcttgtt
    29461 cctatctctc cattgagttc taatatcatt ggtttcattg accaatgaag tgaggacaaa
    29521 ctgttgacca tttctctcaa caaagggcaa ttcaacacca aagacatctc tgataaactg
    29581 ttgatcaagg aggtctcttg gttgcccttg ggcataaagt cgcccatctt tcagtccaat
    29641 aagatggtct gaaagagaca aggcctggtt gatgtcatgt aatactaaca caatcgttag
    29701 gcctagctct tggttgattt tagtaatcag cgtgagaatg tcaagctggt acttaatatc
    29761 caaataagtc gttggctcat ctaaaaaaat aatatctgta tcctgggcaa gggccatggc
    29821 aatccaaacc ctctgctgtt caccaccaga aaggtgttgg atgtcacgat aaacataatc
    29881 actcaaagcc gttacttcta aggcccaagc aaggcgttcc tcatcttctt tggtagtagt
    29941 tttaaaaaaa gaacgacggg caagcctagc catggctacc aattcaccca ctaacaaacc
    30001 ttcgaccact tgatggtatt ggtgtaccac tgccactttt ttcgcaaaag ccttgagaga
    30061 aatcgttgct aattcttcct gctcaagcca aacctgccct tgttttaacg gaaggttttt
    30121 ggttaataat tgtaataagg ttgacttgcc actgccattt gcccccataa tagtggtaat
    30181 tttccctttt ggaatgctaa aggtcaggtc atctaaaaca agtttttcct cataagcaaa
    30241 ggaaaggttt tgcacccgaa tgtgactgct gttcttactc atataatatc agacctcctt
    30301 agcaggtaaa taaagtaagg cccgcctaca atactcatta taatcgcagg gctaatttcc
    30361 aatgggtaag caagacttct tcctaaagta tcggctagca aaaagacaaa ggctccaagc
    30421 aaagctgaaa aaggaattaa gatttggtgc ttacttccaa ccagcaagcg gctcatatga
    30481 gggacaatca agcctaggaa agaaaccact ccaacgatcg aagtggctac cgaagccaat
    30541 aaaacagcaa ccaaggaaat tcccaaccgt aacgctgtag catcgattcc taaatgacga
    30601 atcacctgat catctaaaag aagaaggtta caggtttttg acaataacaa agctagtaac
    30661 aagccaatga atgtataagg gaataaaacc cctacatcag cccatgtttt ttgactaata
    30721 tgacctgcta aaagagcatt gaccatagga ctagctgagg tgaaaaaact ggttaaagca
    30781 gttgataacc ccataaataa agcattaata gcaatccctg ttagaataag ccgaatagga
    30841 ttaagcccct tcttccatgc taaaccataa atcagcagga aagacactcc gcctcctaaa
    30901 aaggatacga ttggaccata cagcagcaac tgcggtagaa gtaaactaga gactaaaacc
    30961 ataaaactag caccactaca aatccctata atagcagggt ctgaaatagg atttttcaac
    31021 actgcttgaa aaagaactcc cgaaacagct atccctgctc ctgctaataa agcaatgaca
    31081 attcttggaa agcgcaaatc ataaatcaaa gccacttggg ggtcataagc cacaaacagt
    31141 cccttgataa ttgcctcata agaaaccgcc aaaccaccaa gggataaggc aataaccgcc
    31201 aaaaacagga ggctgagaat taaaagaact agataaagac cacttctgaa acgtttttta
    31261 gccagtaggg attgatccct ttgtaaatct gatgctgtca tgttacgaat gatctcccac
    31321 gtggtcaaaa agctgtgtta aggtgtccaa ggcttctggg tagttcaatt tagcactcat
    31381 gccaaacagg gtattgtcca aatcatagac tttcccttcc ttgactgccg taaaatgttt
    31441 ccaaatatca ttttcagcaa attctttgtc aaacatcact tttaccttgt ctggaatggc
    31501 gtgagctgtt cgtaaaatca agtcaggctc cttagccagc atgtcttcag gattagctga
    31561 tagaaattct ttctcatctg actgataaac attctcacca cctgccaagt ccaaaagatt
    31621 ccctacataa gattggttcg tcgccaccaa ataactacct ggcaagccca taagaataag
    31681 cactttaggc tttttcttcc ccttacgttt agcttggaaa gcacgataat agtcctggta
    31741 ttgctggcgc aattcttttg cttcttgttg acgttggaaa aggttcccta aatcatcaat
    31801 ggactggtac atgccctcaa cactccgtaa gttcaaaaaa ccatactcag tatccaattt
    31861 ttgatacttg ggttccaaat cttcttgtaa agaattggga ctcaaaatcc aagttggttt
    31921 caaagaagca atcaactcta tatcaggatt catgggtaaa cccacacgct taacagcatc
    31981 atagcgttta ggaagggtat ataatttact atcacaaacc ccaacgaggt ctaaatttaa
    32041 acggtcacag atatcaacca cagcaaccga agtggctaca attctctgct gttcagactc
    32101 tttagccgtt ttagggtgct gattcacaca agctaccaaa aagaatgcca ttaaggctag
    32161 accaattcct ttacatcgtt ttatcatttt ttttcctctt tttccaaacc catacagcaa
    32221 accctcctaa catcagaaaa aaagttggaa agtagtaaat catgattgat aagtcttttt
    32281 tagaccgaaa cttatcttct ttttttaact ctaaagaagt cgttaagccc atcttagaag
    32341 gaagaatttt tttatctgat agactcttgt tatttgatga gttggcttta ggcttattct
    32401 gagttatcat agcacctgtg tgagactcat cttgactttc tcctagtttt gtatcaacag
    32461 gcttttgact gtcttttact tcttgatttt gagaattgtc tgtttcagta acaagctggg
    32521 ccaacatatt acctgaatac ttttgtatta actctgaagc tgacaggtaa aagaccactt
    32581 ctctgcccat aggttcaaca aacatgcttc ctcgaatgat actatttaca gtaggcaaac
    32641 taatagcaat atctagtgtt gtcccattgg tatcagtacc tttttgggtg atattgtaat
    32701 ccactgcctg aaagcttcca gttcctccag gttgtatcca gaactgataa ttacccgaat
    32761 aatcagctaa gctcatacga aaagtaagaa cgatctttcc agcatcagat acttctagca
    32821 tggcatcact atagacagtc ccttcaacca taccttgacc aatatcaaag gaatgctccc
    32881 ctccgctatc ttctatctgc ccagatatcg gatgacgata atttctttga ataatacatc
    32941 cataaatttg acctttatct gcatacacaa cacctgtcat tgttgataaa cttatcatga
    33001 acactactat tacctgcaac aattgcttta tcactacctt tgtcatatgc tcctcttgtc
    33061 tatcttttct tagacatctt atttcatttt ttaaatgatt cccattttat aacatctcca
    33121 aatgtgaaaa acacacctat cttgcgacta cttcaacctg tatcaggaat cctgtcggaa
    33181 ataggtatgt ttttagctct tgctgactag cttttttgtt atttcacttg gtactaagtt
    33241 tcttatttaa ataatgtctt tcgaccaata atgaatccca gagctacgat cataaagcta
    33301 gatagacctg caattaagtg ataacgagag ctactttctt caccatttga ttgttgattg
    33361 gaacgatgtt tcttatcaga ttttttagtc ttagtatctt ttgccgtttt accttcaatt
    33421 gatgtttgat ggtcacgcac taactgcttc aatttctctg ccttatcagt atcatctgtc
    33481 ttagaagttt cttgagttga ttgaccggtt gcttttttag ccaggagatc agttaagtta
    33541 gcaataccag tagcttctga aggaggactt gtaggtgttt tttcttgttg acgattttga
    33601 ggtcctttca actgatctgt tgaagttaga tggctatttt cttgtggatt attagtttct
    33661 ttgacaacct ttgccttctc tgttgtaagg cttgcccagt ctaaacgcat aaaaacggtt
    33721 tgaaggccag acccttttga aatggcatcc atgataggca caaagacctg taatggcaca
    33781 agtccgtctt tcttcgcttg ttcaatcaat ttcatacgca gcacttttgg atagtttttt
    33841 ccataacgat ctgccaatgg taggccagtt acatccgtga aataagacac aacctctgcc
    33901 ttttttgttc gaccaactgg tttaccagct aaatctcttt ggtaaccatc tacgaaatag
    33961 ctcaattcac caaggtagcc taacatttta ccaaccttta tacctctaaa ctcaacttct
    34021 aaataggaaa tacctttttt aactaccaaa gtcactcgat gattaatagc cttgtttgac
    34081 atggactcag atgctaagtc agtttttaac atgctggcat ttaaatagta aataccatca
    34141 cgcaattgtt tttgatttaa tgctctaagg cctttctcaa ctaaatcttt ctgatgtaaa
    34201 tgtggtcctt tcgccacaag gatatcatta gatgtcaaat agatatgttc tttttgagta
    34261 gcaaatttct ttgttattaa agctttgcga atccgatatg tacctggatc ttttaaagaa
    34321 aactctcccg ttaagtcatc tttcggatca tttgagagaa gcttttcgtc aaccgtcaca
    34381 tactgtccat tggaagcttt tttttgcaac tgaatcacaa tactccaatc gacttgcata
    34441 tcattaagta aagagacagt atctgaacct ttttcttgta acaattgttg atattcttca
    34501 atagacacta gttctttatc aatggcagaa tttgtttttt gctcccaata atacaaatct
    34561 aaaagactga aagcttgatg atattttatt ttttcgccat ctaaggaagc ttcaagtttt
    34621 gcaatatgtt tttgtggagt cagtttgtgt tgtccgataa gagctcttac ttttggactc
    34681 acacttttta tctgattgaa cttcacatct aaattaagcg tttcaacatc tggaaatact
    34741 gattcttcaa cctgagtaag caagttattg aaaaaatcaa gttttgttaa ttggttattc
    34801 tgtttaaata taccatttgg aagatttgaa atttcattag ttgataaatc tagtacagat
    34861 aatttaggaa gatttttaaa tgaaatatta tcaatacgag taatatgatt tctacttgcc
    34921 acaatagtgc ttaaggcgcg caatttttct attgtttttg gcagtagtgc tagattattt
    34981 tgagataagt cgataaaatt aagtgatgtt agaggctcta gcgctttttc aggtatctcc
    35041 tcaagactat tttctgcgaa acctaatgaa gtcagacgag acaatccttc aaatgggtta
    35101 tcacaaagtc ggccaatacg attcttggaa agatcaagtt gctccaggtg atgaagcgac
    35161 tggaatagtc ctccttcaag agagtgaata aagttacttg ataagtagag ttctcttaat
    35221 tgagcatttc ttttaaatgt atctttgtct agataagtta aatgattact tcttaagtta
    35281 agaaatcgaa gttgcttcat ttgactaaat aactcttttg gaatttccgt aatttggttt
    35341 ccatccagat gtagttctgt aatattttta gcatatttca ataaagaaat atcagttaac
    35401 tcgtaatggt ctagacgcaa ctcgcctcga atctgttcta attccgtttt tgataattta
    35461 ccatcgccgt ctaaatcttt gccaagttta actaaaactt tttcaagacg ttcagtccca
    35521 accccttttt ctttatcatc agtttctacc tgataaccac tccagccttt ggtaacggtc
    35581 ttactaaagg tcatgtcaag tttggtgtat ttgtcatagt ggtttaaatc actttcttga
    35641 cctcccatgg ctgataccaa aacagcacct ttgtgtaatt tatccaaatc atcaataggc
    35701 atggtaaatt cgcttcgaat atagctacca ttgatatctt tttggccaac ttgtttacgc
    35761 actgctgctg ggtaggtccc tttgctttca atagaaaagt caatcaaaaa ttgtcccaaa
    35821 gcagtattaa gcatggaaat ttccattgta ccatctgctt taaccactaa tttggctctt
    35881 ttatcaaaag caccttgaag catggaggac tcttctgagt tttctttatt agctttaaag
    35941 tttagcgtat aggttccttc tgtgagattg ttaatagaaa cctcacctgc ttgataagac
    36001 tcgatggtat cttttaacag tcgatgagta tcggcgagta gcttactatc tttgatttct
    36061 ttgtaagaat ccttgatgac ttgaagtttc tcagccagat ctttgaccgc gtctttgttg
    36121 ctttctttag caataatcgc atccgcttct ttgatagctt tttccaaagt ggtgacatcc
    36181 aactttgttg attgtctgtc ttcagcagtc acatgttgtt tttgtttggc agatacaaaa
    36241 tggatttgac catctttctt ggtaacggta atggtaacgt cttcaaatcc tgttgaggat
    36301 atcacgattg tattttctcc atctttgaaa gcttttgttc caagatgaag ccctgtcata
    36361 ttcgagaccc agccattggt atcttttaca gaatctgaaa taagatcttt ataaactgta
    36421 ccattgactg taacctttgt gatttgctga gtcaatgctt ttatctgttt gttatcagaa
    36481 taacgatcaa tttctggaaa taaaattgca ccatcttctt gactcaattt tgttattaat
    36541 gacaagttag cagtattttt cccagattta acaacttttt gtgtgccttg gttttgtggc
    36601 actggtttat cactgagcac atcttttttt aatgaatcct gatgatctgt tgttcctaat
    36661 ttttgagctg aaataaaggt cactttatcg ccctttttaa taaaggtaat taggatatca
    36721 ccatcttttt tattaacaat agtcaattca tgcttaccgt ctttaataag gttagcattg
    36781 atcttaatcc cttggtagtt aatatcaaag gttcgctcgc cttccaggct tttttcatag
    36841 acatcattat caacaataac cttttcaata tgtttataat actcttttcc agctgattga
    36901 ctagcgtaag ggcctatctc ttcaactaaa agtcgattat cctgagttaa agctactgtt
    36961 gtcacgagtt gtgactgaac taaaggctct tgtgatttta cagtttgagt agcctgaatg
    37021 agaacaaggg cagatattgc cacaaacgca catttgctga tttttttcat tttcaatcaa
    37081 ctttctaaaa atttttatga ataagctaac ttttttatta actgaactta atctatcact
    37141 ttgtgattat tttgtcaaga ttgtttccaa tggtccaatt gtctgttaaa aagctccact
    37201 atgtgagcca agacactagc aataagcctg gattgataat gatgatatct ctgataaaag
    37261 aattcctcta caacaatatt actgagataa agctagcctt aagatagtta ttactagggc
    37321 tgattcaatc attacttcat tcacaaaaca tgtaacacgt tataagctcc ataattgtgt
    37381 taggagacaa catgagatgt cactactgca tattcatcac aataaaaaaa gacaatagcc
    37441 ctaatcgtgc tattgtctca aaatcattta tttacttgaa actttatcgt gttacaccaa
    37501 cagtttaaaa ggcctaactc ccgctaagaa aattaagcct taagaaaagt cattagttat
    37561 tagtttttac tcttgccaat aacatatgtt agctgttcag cctgctgagc tgtaaaggta
    37621 cgataagaaa tcttacctaa gccgatacag ttagactctg aaataagaat agacccatct
    37681 tttctaacat cttctacaat tgatacgtgg ccataagtgc catcagcgcc tgcttgcccg
    37741 ggtgcaaatg aaatagcata acctactttt ggagtctttg acagggcata ccctgcttta
    37801 tacttccaat ctccaccatt tcccataaaa ggatcaaatt ggtaacccaa ttctttggcg
    37861 cgattataca cataccaagt gcattgtccc caagcataac tcgaagcttg ataacccaag
    37921 acatcataac tcttagagag cttataacct gctggcacag atgcaaaact agctgatgac
    37981 tgcactttca attcggctgg aatggctggt gtgccaccat ggtcatcaat ccacttatcc
    38041 aggtcttcca taatttgtgc gcgacgttta ccactaccag tagtatcagt aaaataaaca
    38101 cccccgtcac ttgcaaagtt taattgacct cgtgaaaact tagccgcttt taaatcttga
    38161 agtgcaaaat tgctattttt gtttttaata atggtatctt gtgtcatttt gacaatagca
    38221 ctatcatcat taaacttact tgcttgagtc ggatctagat caaaagctgc atagccaaac
    38281 atattagctc caagcaaagt cgcaatccct tgagttccta aagaactctc agacatcgca
    38341 atagctacga tagctcgaac atccagccca cttttctttt cccattgcaa tagcttctca
    38401 ccattaatac gtgtgctgtc ataggcaatg cctgttgatt ttaagtaact atcaatctgg
    38461 tcagctttaa taccataacg gcgagataaa agatggtggg tataggcatt tttaccactc
    38521 caatgctcta catatgccgc gtatgtgttg acagaaggga tatctatctc actcaaatct
    38581 aaatctgata cgtaaggtga caacgactga ataggagttc ttacctctgg caactgtctc
    38641 gacaatgaag aagcaggtgc cgtatcaact ttagatggtg atggtttggg ctgatcagtc
    38701 ggttttggct ggtcagttgg tttcgaatga tcagttgatt tatcatctac ctggttttct
    38761 gcttctgcct tgttgtccga agaacctaca gcagactgac tagaatcgct tcttttttta
    38821 tcatccgcgt taacaagact attagagttt gtttctgcag aagcatcaag gggaccttgg
    38881 tcagttttat ctgatgttgt aggtgctgca tttttattat tttcctcttt tgaagaagaa
    38941 tcactggttt catttgtagt tgctttatgc gtctcaagca ttacatcttg agccaacact
    39001 gtcatgcttt ctgctgtcgg ggctaagaga cttagtagca tggcaactct taatagtttg
    39061 tttttattca tatattaatt agtcacttct ttctaatgtc ctcactttat tataacatta
    39121 aagataagca caatgcaatt atttttacgt gattttctta atatatccga ggaatacggt
    39181 cacttaaaag gcatagaact tcataattga ttgtattacg gtaatttgcg atatctgttg
    39241 tagaaatatt tttttgctga ttgctgccaa tcaaagtgac ttttgttcct aaaggatatg
    39301 ctttgggaag tcgtatggtc agttgatcca tcgatacacg ccctataatt tcacagaatt
    39361 gtccatcaac taacaccgaa aagccttgca tgttcctggt ccagccatct gcataaccga
    39421 ttgggacggt ccctacatat tcagactttt tggcagtata agtagctcca taaccgactg
    39481 tatcaccagc tgaaatcatc ttgacatgca ctaagctaga ttctagagat aaagcctctt
    39541 gcagtggaaa tggtaagctt agatcagaac cacttggatt caaaccataa ctaacaattc
    39601 ctaaacgaac agcattaaaa atggtatcac tatgccagat acttgtggct gaattactag
    39661 catgtactaa acgaggctta tcctcaagtc cagctatcag ctttttaaaa aactgtaact
    39721 gctggttaaa tttagtatca tctgcctcat cagctgtggc aaaatgagta aaaatacctt
    39781 ctacatcagc acccaactct tttagactat caatcaataa attgacttct tttgaagaac
    39841 gaagcccgat ccgccccata ccagaatcaa cttttacatg aacttttaag ccttgacatt
    39901 cttttttctc cagtctagct aaagctatcc agtctaaact agcgattgta acagtaatag
    39961 cattagcaac tgctaactct aattcatttg gcaggaggac cccaagaatt aaaatctctt
    40021 tatcaatacc tgctttacgt aattgcaaag cctcatcaag atttgacaca cagtacccat
    40081 ccacttgagg taggagtgct tttgacacct ggacagcacc atgaccataa gcatcagcct
    40141 tgacaactgc atacgttttt acccctagtg gaatatgctt ttgaacactg gcaacattct
    40201 ccttaatagc ttgtaaattg acccttgcaa ctgttgggcg atggaaactt gaaatcattt
    40261 tttatcctcc aaaataacac tagcctgtac ataattgcca ctatgtgaga tgctaataaa
    40321 actatttcct ttaaacggag attttgtcag aatgggacat cctctaacat catttaaaat
    40381 ctcaatatct tgaaaggtta accgcccaat acctgtccct atagccttag caaaagcttc
    40441 cttacctgac cagcgtcctg ccaaatagct gagtcgacgt ttgtaaggaa aactctcaaa
    40501 aatagccaat tcctgctcag ttaaaatttt ttgagcaaag cgaggatttc tttgataaac
    40561 tttttcaata gctgaaatct cttgtaagtc tattccatgt ccaacaatca ttactttcca
    40621 ccaaacctta tttcatctta atgttagaag atttaaacag tgagaagctg agaattattc
    40681 tcagcttctt tctatatacc taactttgtc ctgttgtgtc tcgttcttat gagaaggatt
    40741 tacgaccgtg acaatttttg aattttttgc ctgaaccaca tggacaagct tcgttacgct
    40801 ccactttggg taaatcatcg gtgttagctg actgctgcga ttggatgttt tgaggtgctg
    40861 ctgttgtggc acgttgactt gcacgttcac gttcttgttc gtgaatttgt gctttcatca
    40921 tggtacgtgt tacatcaaac tcgatagcac caatcatatc ttggaacatc ttgaaacctt
    40981 ctgcttggta ttccaccaca gggttatttt gagcataccc ccgaagtcca acagcattac
    41041 gaagttgatc taaggcatca atgtgttcag tccatttgtt atccacaatc atcaaaatga
    41101 gtactttttg gaattcaata atagcttctt gatcacgaag ttttgatagt tgctggtcgt
    41161 agatagcaag cgctctttga taaagcttct ctttgatttg atcatctttt aaaccacgta
    41221 actctttagc actaatagac tcttctggta ccagcgaggt cctagcaaaa gttacaatag
    41281 catctatagc atctttacga ttgctacgtg catgagcatc tacagcacgg tcgatagtac
    41341 gcttgatcat agctttaatt tctgggccaa gatctcgatt agcagttatg acatcacgac
    41401 ggttagcata gataatttca cgctgttcac gcatcacatc atcatattgt aagacctgtt
    41461 tacgggtatc gtagttattt ccttcaaccc gtttttgagc agattccact tgacgcccta
    41521 acatacctga tttaataaca gtgtcttctt catctaattt catccgatcc aaaaaggctt
    41581 ttatacgttc agagccgaaa cgtctcatca aatcatcttc taatgaaaga tagaattggg
    41641 attcacctgg atctccttga cgacctgaac gtccacgaag ctggttatcg atacgacggc
    41701 tttcatgacg ctctgtacca atgacacata acccaccaag ttcacgaaca ccttcaccaa
    41761 gcttgatatc agtaccacga ccagccatgt tagttgcgat tgtaacagca ccacgttgcc
    41821 cagcattcat aatgatttga gcttctttaa agtgattttt agcattcaaa acctcatgag
    41881 gaatccctgc ttcaaccagc ttgcgtgaaa tcaaatcact agtttcaaca gcaaccgtac
    41941 ctacaaggat aggttgtcct tttgcatgac gcgttttaac gtcttccaca actgctctaa
    42001 actttgattc taaggtcggg taaagcaaat cagtgtgatc aatacgggca attggacgat
    42061 tggttggaat tggaataata cgcatgttat aaacttcgcg aaattcttct tcctcggtct
    42121 tcgcagtacc agtcatacct gccaattttt tgtacatacg aaacatattt tggtaagtga
    42181 ttgaggcgct ggtttttgat tcttcctgaa tacgaacgcc ttcttttgcc tcaatagctt
    42241 ggtgcaagcc gtctgagaag cgacgccctt ccatcgtacg acctgtaaat tggtcaacaa
    42301 taagaatctc accatcttcg ctgaccacat aatcgatatc taacaacata atatagtttg
    42361 cacgaagggc gttgtctata aagtgagtca aggctacatt ttcaatatcg taaagattgc
    42421 tcaagttaaa ataactctca gctttatcaa tacctgaatc gcttaatcca atcgttttag
    42481 tgggcacatc aataacataa tccactgacg tcagagtttt tacaaacatg tcagcacgaa
    42541 tatacaattg attggtttca gagctaacag caccagaaac aattaaaggt gtccttgcct
    42601 cgtcaattaa gactgagtcc acttcatcaa ccaaggcaaa attgagtggg cgttgtacca
    42661 tgtcttcctg gcgaacaacc atgttgtcac gaaggtaatc aaaaccgact tcagagttgg
    42721 ttgaataagt aatatcacaa ttataagctt cacgtttttc agcaggagac ttagcagcta
    42781 ggttgatccc aactgaaaga cctaaccagc tatacacttc acccatttcg gtagcgtcac
    42841 gcgttgaaag atactcatta acagtaataa cgtgaacacc ctcaccagca atagcattga
    42901 gataaactgg catggtggct gtaagggttt ttccttcacc agtacgcatt tcagggacat
    42961 ccccgttatg aagaacaatt cctcccataa tttgaacacg ataagggaac aagcccaaca
    43021 cacgttttgc tgcttcacga acaactgcga aagcttcagg taatagttgt tcgagggtct
    43081 cacctttttg atagcgttct ttaaattcaa gtgtttttcc ttgtagatct ctatccgaca
    43141 atgacgccat ttggtctgcg taggattcta ctttttttgc aattttttct aattttctta
    43201 gttcgccttt gtcattttcg ataactttgc gtagaatatt ggccattctc tttcctttcg
    43261 atcatctaat catttcattt taacataaat atgcaggcag ttcaagaaag gttggtaaag
    43321 ttatcagaga aacagagagt cataatttta tccttttttc tcatattgat accatggtat
    43381 taaacgagtt gattggggtg actcacaatc atttctaatt gaccatcaaa tgaccacgat
    43441 ttaacatcgt taggcaagat aaagtgcatg cctttttcta gctcataagc cttctggtcc
    43501 acatagagtt ttccttgacc ttttaaaaca ctcactaaaa gataaggcgc agcttgtttc
    43561 atgtcaacca tttgactagt tacccatttg taaacagtga aaaatggtgt tgagactaaa
    43621 gttgttgcta ccatattatc caaaaccata gtggctggca cgctattttc tggcttacca
    43681 atcgttaaga catcaataga cttttcaata tgaaggtcac gaagattacc attaacgtcc
    43741 ttacggtcaa aatcataaac ccgataagtg gtatcagatg actgctgggt ttctaaaata
    43801 agaattccct tgccgatcgc atgcatggtg ccacttggaa catagaaaaa atcgcctgct
    43861 ttgactggga cacgagtcag caaatcatcc caagcgcctg cttcaatcat ggcacgaagg
    43921 tcttctttgg acttggcctg atggccgtat acaatttcag aaccctcttc ggcagaaata
    43981 atataccagc attctgtctt gcctaattct ccttcatgtt cacgtccata agcatcatca
    44041 ggatgaactt ggacacttag ccagtcatta gcatctaaaa tcttagttaa cagtggaaaa
    44101 acttcttcct ttggattccc aaacaaggct ggctcttgca catataatgt atttaaaggt
    44161 tgtccttgat aacgtccatt agtaactgtc gaaacaccat taggatgagc agaaatagcc
    44221 caatactcac ctgtggtgtc acttgggatg ttgtaagcaa agacatctct caacttggtg
    44281 ccaccccaaa tcctgtcgtg catggttgat tttagaaata atggttctga cataatattc
    44341 ctcgcttctg atgttaatct ctgtttatta tagcatgttc tagctgactg cgctttcttt
    44401 tactagacaa gcaggcaaaa acagatccta ttttccttgt gcagccaact tggccaaagc
    44461 aaaatttccc agagtagcgg agccattatc agcaacagct ggagtaacaa tgtagtctgt
    44521 caaatcaggg actggcaaat aaccgcttaa aagggtagtg aatttatcat gcacgcgcaa
    44581 caccatatgt tcttgcgcca tgacacctcc gccaaaaaca atcacttgag gacggtaaag
    44641 catagttgct tgcagcgctg cttgggcaat gtagaaggct tgaatgtccc aaacatcagc
    44701 ttcctgatca agtcgttcac ctctcactcc cgttctggcc tcaatacttg gacctgctgc
    44761 catcccttcc agacaccctt tatgaaaagg gcaaacacct aaaaatccct tggccatatc
    44821 atcaggatga ggcatgacat aggtatgacc cgcttctgta tgacctaatc ccccaataaa
    44881 gtggccatgt tgaatagctc ccgccccaat accagtacct atggtgtaat agaccaaact
    44941 ttccacacca ggacgagcaa gcacctcacc ataagcagag ctattaacat ctgttgtcac
    45001 atcaaaagga atcttaaaag cagccgaaag ttgtcctaac aaatccacat tagcccagcc
    45061 tgacttagga gtggttgtga tataaccgta agtctctgac gacggatcaa tatcaattgg
    45121 tccaaaagaa ccaatagcca ttccagccaa atcggcctca aaggttttaa aatatgcgat
    45181 ggtttgcgcg atggtttctt ctggtgtggt ggtcggaaat tgtgttttat ccaccactgt
    45241 aaactcctca tcacccacgg cacagacaaa ctttgtccca ccagcttcaa tgcttccata
    45301 taattttccc atgttttctc ctttttcttg ttctttttta tctttatgat gacacaggct
    45361 cttatcaaga cagccatgtc tcacggacaa gtgccacttt ctggtagtct aacgattatt
    45421 tagctttatg tcatcaaaac ctataaaaga ctaaaaatct gggactattc atctcagatt
    45481 tttagttagg ttttaaagtg cttaaatcaa ctttgagaaa ctgtttatct ttgtaatcgt
    45541 aggactttaa tatcaatcct tcagcgtatt agcgacatca tttgataaac gttgtccgag
    45601 gatttgaagt tcggtatatt gagggtaata agagctagct ccaccatcta cacaaaaccg
    45661 ccaataccga gataaaacat tggataattt actattaaat atcgcttttg catcatccat
    45721 ctgagcaaca tcagtccaat tttcatcatt cgacagatac tctttacgat tttttatgtc
    45781 cattttttct aaattaatag ttgtatcttt taaaatctga agacgtcctt tagccacgtt
    45841 taagctacta tctgtcttta tttcagtatt tgtctctgca ttaaataaac gccattcctt
    45901 cgcaagatta atttctccta gatcaaaagc tatccagtta gtttgtcccc aagtgaagaa
    45961 tctatctgac ttttcaccat cgaaaatctt ctttgcttgc tcaaagtccc cagatgtacc
    46021 aatcacttta gccccttttg ccagattttc catcatgatg gcaccagatc ctatattgag
    46081 tttcatgtgg tgaacaactt tttccccatc agaaacatct actaagtaag tttcatcagt
    46141 agtagcagtt accttagaag taactgtttc tcctaggtta gaagcagtta aatgaacctt
    46201 gtaaccttta tagtctttac gaaaagcttc ataagtatag tctttagaca catattgtcg
    46261 accatcgaca gctccttctt tatagatagc aaatgcttct tcgtctccaa taaaggtatt
    46321 acgtttagta acagttccaa aaacaaaatc agttaaaata tcatgttctg cattatcaac
    46381 atcataatga ccttctttgg tatcatacgt ctgaggataa taacctttcg gtttttgatt
    46441 ttcaaaagcc gtatttttca ccgttatttt ttgatgattt gaaacctgct ccatcaaagt
    46501 cattaatagt ttacggtctt cactcttttc cgacaagtcc aaactattat gtgaaatatc
    46561 aaatgatgtc aaatgcgtaa tactattcac gtctataccg tctaaagttt gacgatttag
    46621 accactaagg tttagttttt ctaaaccagt catgcctacc ataacaagct cagcatcttt
    46681 tttcatgctt tccggcaaaa gttctggagt aatttcttta acgttagata gctggcgcaa
    46741 ctctaatttt tgtaacttgc ttaatttttc tagtccttta agattttgaa tcttatctcc
    46801 tgtaagcacc aatgtcttgt tataacgttc caaatcgcct ttatactgtc caacttgttg
    46861 aatgatttgt tctcttaatg ctgggtcagg aatgtctttt tgatcaatga catcatagcg
    46921 tttgtcttcg gtcatcaatg tttttaattt tcgagatacg gtgtagtcag tatgtgagat
    46981 attatcgact tcatgccgtt gtaaatttgt actagtccta tttttatatg ttgaaggaac
    47041 atgagccact ccatcacgat caatagcata agagaatata cctgctttta aaccacctgt
    47101 actaggttgc cactctgcat attttttagc acgtgttcct tcaatatctt tccctttttc
    47161 aggattgtta gggtcgtatt cgttaacatc aaaccataaa ttccctttgg acgcagattc
    47221 ttcaaaaaag gagaatccaa tcatgaactg gctagcatca atataattct gatattggtt
    47281 ccaatcagag tttatagtat ccacttcagc ttctccacct tgtgaaccat aatattgtct
    47341 aagaagataa tcaagatctt ccgctatccc tttaaatatt ggattatttt caacacttag
    47401 ggtagtgtcc atgatgagca atttagattt atcactacca tttttaccta ttaactgcgc
    47461 aatctcttta aaaacattta gagcacgagc atcttcttca ggtgttcttt tgttcgtaaa
    47521 ttcgtgctca atatcaatat ctagtccatc gacaccacga tcagttacaa atgccttgac
    47581 aatggctgct gctaaagctt tgttcccctc aggagtatca ggataatctt tagataaacc
    47641 tgtacgtcca tttaattcgt taacaccaat tgtctgaaca agtgccgttc cctgttgatg
    47701 taatttatgg acataactgt cctttaattc agaccaaaat ggactatctg aagctgtatg
    47761 gtcatgaaaa acaaataaga tatcaacttc ttttgggacc tcagccatag tattttctgg
    47821 atgttgctgt ttaccatcta ttcctgttga agcacgatca tgccatgtcc taaaataacc
    47881 agcatatagt ggtccgcgtt ttccttcacg gatttcctgt accaatttag caccaacctg
    47941 ctggtctgtc tttcctgttt gaacagtctt ctcctccgct tttacagtat tgagtgaatc
    48001 atggtgggtc gctaaggcag ctcccatcaa cgttgcagca caaacacacc ctagtgttct
    48061 ttttaccaac aaatgtttat ccatttggac actccttatt tttggtacta agtcatggct
    48121 tcccagttga tataccatct atgtaagcgc attcctatag ttcgccttaa gtataacaac
    48181 actttattaa aaaaaacaag gtacaaagta taggtaaaat aacacaaatt taaggttttt
    48241 aggcttttct catttttttg ccaacctgcc attcatgaca ggacaaaaga gctgcttagt
    48301 cagctctttt gtccttattt gataagtgcc acttgatcac caatcaaaac atgtccttga
    48361 gcaagaatgt ccacgctttg atagtcagcg ctattggtca caatcatcat ggtggtgtca
    48421 tctagtccag cttctgcaat cttgctagga tcaaagtgtc caagaagatc acctttttta
    48481 accgcctgac ctactgctac aagagattca aagccatctc ctgccatcga cacggtatca
    48541 ataccaatat gaagtaacac ttctgctcct tgacttgacg ttatagcata ggcatgacct
    48601 gtttcaaaga caatttcaac tttaccatca actggtgagt atagggtatt atcatctggc
    48661 ttaattgcta agccttgacc catagcacct gatgaaaaaa cagggtctga aaccgcagat
    48721 aagtctacaa ctgttccatt caaaggacta tataaagttt cctctgctaa ggctggctga
    48781 tcagccgttt gatcaacttc gacagctggt aacggaaggg tttctctatc ttgataaccc
    48841 caaatataag caattgcaaa agctacccca agaccgacaa gcatagtcac aaggtattgc
    48901 aataattggc cattcaagta aaggagagtt cctggtaaga ccgtaatccc aaaaccagtt
    48961 cctgcaatgc caaagagccc agcgacccaa ccacctaagg caccaccaat aagacctgaa
    49021 acaaagactt ttggataacg gaggttgacc ccaaaaatag ctggttcagt aatccctaaa
    49081 agagctgaca aggttgatgg aaaggccaga ccttttagtt ttgttgattt ggttttaaca
    49141 gcaacagcta aggtagctcc agcttgagca gctgttgctg ctgttaggta agcattgaaa
    49201 ggatcttttc cggtattggc aattagctgc gcttctagga agttaaagat atggtgaata
    49261 ccagtaacga cgatcaattg ttggattccc ccaacaatca agcctgcaat accaaacggc
    49321 aaatgcaaga cggcctgtgt cccagccaga acaaggtttt caagagaatg gaaaactggt
    49381 ccaatcacaa atagtcccaa ggtactcata atagcaaacg ttaaaaacgg tgtgaccaat
    49441 aagtccaaag cttctggaac ctttttgtgc aaccatttct ccaacttagc tcctaccaga
    49501 ccaacaaaga aggcgggtaa aacggtacct tgataaccaa caacaggaac aaatccaaag
    49561 aaggttagcg gcttaacatc tccaccagag gcaactaccc aagcattagg caactcattg
    49621 gaaaccagca tcaatcctaa aacaataccg ataataggat tacccccaaa gaccctaaag
    49681 gctgaccaag ccaccaaagc tggcaagtag acaaaggctg tatccgttag aatacgagtg
    49741 tacatgagaa aattttcccc gtactcatgc accccaaata aatccataat agctggctgg
    49801 gtcaccaaac cacgaacccc cataaagaga cccgttgcta caatagctgg aataatggga
    49861 acaaagacat ctccaaacgt acgaatcgcc cgttggaaga tattgccttg tttgcctgct
    49921 tctgcctttt gctcactggt tgatgacgtg ggtaaaccaa gagcaacgac ttcgtcataa
    49981 atgttattga cggtaccagt tccaaaaatc atttgatatt gaccagagtt aaagaaagct
    50041 cctctaacct tgtcaatagc ttctgctttt tccttatcaa tctttccttc atcataaacc
    50101 atcacgcgaa ggcgagttgc acagtgggca acacttctca cattttctcg gccacctaaa
    50161 gcctcaatca cttcagctgc aatctgacga ttatccatgc ctaaaagtct cctttttcat
    50221 ttggtgttag tccctcatcc attctgccag ctttgtggct aagaatgtgc atgaccaacg
    50281 ctagtgaatc cgcttcactt cttgactatc attttatcac taatattttt tatgtcaagc
    50341 gtttaacata tttttatttt atatgcttta aattcttgat ttttaaacag aaaacgttta
    50401 gtatattctt gaagacgact ataaaacaag gagattttga tggatctacc acaagctatt
    50461 cgctaccgcc cttacaaaga gtggagctca aaagactacc aagctattac tgaaaaaatg
    50521 gcccaatccc catggcacag ccaatttcat gtcgaaccta agacaggatt actcaatgac
    50581 cccaatgggt tttcttattt caacggtcgc taccatcttt tttatcaaaa ctggccttat
    50641 ggcgctgcgc atggtctgaa acaatgggta cacatgacat ccacagacct cgtccatttt
    50701 acggaaacaa ggagccgcct tctgccagac cacgctcacg atagtcatgg ggcttactca
    50761 ggttctgcct atgctattga tgacaagctc ttcctctttt acactggtaa tgttcgcgat
    50821 gccaattggg tcagaacacc attacaggtt ggcgcatgga tggataaaca aggaaatatt
    50881 tccaaaatcc cgcaggtttt gattgaacag cccgatgatg ttacagaaca ttttcgggat
    50941 cctcagcttt tttcttatca aggtcaattc tatgctatta ttggcgccca aggtttagat
    51001 ggcaaaggaa aaatcaaact ttacaaagct gtggacaatc atgtggacaa ctggcgattt
    51061 ataaccgatt tggactttga cgattctggt acggaataca tgattgaatg ccccaacctt
    51121 gtgtttgtcg atgacaagcc tgttttgatt ttcagcccac aaggactggc taaagctgat
    51181 ttagattatc aaaatatcta ccccaatacc tataaaattt ttgaaagctt caatccagaa
    51241 actggccaat tgctgggtgg gggggccctt caaaatcttg actttggttt tgaagcttat
    51301 gccactcaag cctttagtag tccagatggc agggttctag ccgtgtcttg gattgggtta
    51361 ccagatattg attatccgac agatcgttat gactatcaag gagctcttag tttagtgaaa
    51421 gaattaagga ttaaagacgg aattctctat caaacacctg tttcagccct acaaaatctt
    51481 cgaggaccag cagaattatt tcataataaa atagacagtt ctaactgtta tgaattggaa
    51541 ttgacgattc caggccaaaa aaagcttgac ctgctcctat ttgccgacca aaaagggaat
    51601 ggcctaagat tgaaagtgga tacaacaaaa ggacagttaa gcattgaccg aagtcgggca
    51661 ggggttcaat atgcccaaga ctatggtacg gtgcgctctt gccaaatctc acaaggccat
    51721 gttacactta atgtctatgt ggacaattcc attcttgaaa tctttattaa ccaagggcaa
    51781 aaagtcctaa cgagtcgtgt tttcccaacc caaggacaaa caggtatcca agtagtagaa
    51841 ggacaagctt ttggacatta ttatgaaatg aggtattagg caagtggtcg caaaattaac
    51901 agacgtggca gccttggcgg gtgtcagtcc aacaactgtt tcgcgagtaa tcaacaaaaa
    51961 aggctacctt tcccaaaaaa cagtgaataa ggtgaataag gccatgcgtg aattgggcta
    52021 caagcctaac aatctcgcta gaagtttgca aggtaaatca acccaactca ttgggcttat
    52081 cttccccaac attagcaata tcttttacgc tgaattaatt gaacatttgg aaattgaatt
    52141 gtttaaacag ggctacaaaa ctattatttg caatagtgaa cataatcccg tcaaagaacg
    52201 cgaatactta gaaatgcttg cggccaatca agtggacggc attatttctt ccagtcataa
    52261 tttgggaatt gaggattatg agcgtgtcga agctcctatt gtagcttttg accgtaatct
    52321 ggcgccaaat atcccggtta tttcttcaga taattttgaa ggtggtaaat tagccgcaca
    52381 aactttgcaa aaacacggtt gtcaaaacat tgtcatgatt acaggtaatg acaattctga
    52441 ttcgcccaca gggttgcgcc agctagggtt taactaccag ctcaaacgaa gtgcagaaat
    52501 catcaaatta ccaaataacc tatctcctgt tagacgcgaa atggaaatta aatccatttt
    52561 ggcaactcga aaacctgatg gccttttcgt ttctgatgat ttaactgcta tcctcattat
    52621 gaaagtagcc aaacaacttc acattactat tccagaggat atgaaagtca taggttatga
    52681 tggaacgaca tttatccagc aatatgttcc tcaattagcg accattcgtc aacctattga
    52741 tgagattgct aaattgagtg tcgaaatact catcaaaaaa attaaaaaag aaaaaaccag
    52801 taaagactat attttaccga ttacgctact tccaggagca agtatttaaa caaaacataa
    52861 ccaatcacta attactctaa aagacaaaca agcatactct ttctagatgc gagagtatgc
    52921 ttgtttgtct tttaatattc gtacataaat tgaaaaaatc ggatacaatc ctaagattgc
    52981 tccgacttat tatgatttat ttgctgaagg agcttccgag acatattggc taagtaagcc
    53041 attaataaat ttagcagagg tttcatcaga atatttttta gctacttcaa tgatttcgtt
    53101 tagtgcaaca cggtctggtg tttcgtcaaa atacttgatt tcaaaaagac ctagtcgtaa
    53161 taacgttttg tctgttagtg tcaagcgttc taacgaccaa ccttttttca aatgagttga
    53221 tatcaagtta tccaactctt ctttatgatt attgacaccc gtcacaagac ttaataaaaa
    53281 aatcggcagc tccaatactt gagcgtcctc ccctgttact ttatcataac cataggcaaa
    53341 ctgagaagct gccaataact cagctcccat ctctatgtta aataaagcct gaaaggcacg
    53401 ttcacgcaaa tctcttcttg aattttgaaa gctgttagtc atccaagaaa tcctcatcaa
    53461 aaagtgactt caaatctggt tttggtgtct tttccgcaac aataccttca acatggatat
    53521 tgactgctga gattgtcact tctgccatat catataccgc tgatttgaca gctttttgaa
    53581 tagccataga gaccgtagga accttaacac catactgcaa ataaacatag atatctgcag
    53641 ttacgctacc atcttcttgt gtttgaaggt aaaccccttt gcctagactt gctttattaa
    53701 agctatctgc catttttttg ttatgaaggg aatgaacgcc ctcaacttgt gtggtagcaa
    53761 tcccagtaat aacctcaagt actcgtgatg aaataacgat ttcaccgata tgttcagttg
    53821 tcatagcatt tcctttctct tctttagact aacctgttct gacaaaggat taagcacgag
    53881 aaacgtaagt accttctgca gtgttgatga ttagtttttg accagcttcg ataaagtctg
    53941 gaacgttaac cacaagacct gtttcaagag ttgcaggttt ccctgaaccc gtcactgtcg
    54001 ctcctttaat agatggttgt gtttccgcaa cggtcaattc aacagttgtt ggaaccgtta
    54061 ccccaatcac ttcacttcca taaaattgga ttttcacgtc tgagttttca agaatgtaaa
    54121 gcaattcttg ctcaacgtta gcaactggaa tttcgtactg atcataagta tcagtgttca
    54181 tgaagtaagc agtgtcatcc attttgtata ggtattgtgc tgggacagtt tcaatgatgg
    54241 cttgctcaaa tttttcatct gggcggtaag ttgtgtcaaa agtagaacct gtacgcacat
    54301 cacgtagttt catacgcatg atagtgtttc ctttacctgg tttgtggtgg ctagcttcaa
    54361 ggacacgaat taattttcct tctgcttcaa atgtcatacc tgctttaagc ttacttgctt
    54421 caatcattat tattacctct tactaaaata tttatcactt cattttacca caaaagtggc
    54481 cttggctcaa atcttttatg accgtccttt taggtacact ttctattgtt ccttatcgcc
    54541 tcctaaaaca atttgaggca catcatgttg cacataggca accccttttt tctccatcag
    54601 ttcaatggca aaggggtgcg gacggtaatg tgctttatag gtaatctttg taatccccgc
    54661 ctgcaaaagc gccttagtgc agttaataca aggaaaatga gtcacgtaaa tttcagttcc
    54721 gtccgttgaa attccttctt tcgcacattg aatcaaagca ttcatttcag catgaacagt
    54781 gcgaatacaa tgaccgtctt ccatataatg acccgcttcg ttgcagttat ccgtagcaga
    54841 aactccgcca ttgtaacctg tggcaataat gcggttatcc tttaccaaaa cagctcccac
    54901 aaaggcgcga tcacaggtag agcgcttgga aatcagctct gcattggcca taaaatagtc
    54961 ttgccatgat aaacgatttg tcattgcttc tcccctaatc ctttcctgaa ccattctttt
    55021 acaatacaat taattctttg ggtgccaagg tcaagacttg acaaccagtt tttgtgataa
    55081 ccaagtcatc ttcaatacgg acaccatatt tgttatccaa atagatacct ggctcgtctg
    55141 tgaccaccat tccagcttgg agaagttgct cagatttccc caaaaatgga ttctcatgga
    55201 tgtcaagccc gataccatga ccaatgccat gtgtgaagtg actgccataa cccgcctcag
    55261 tgataagttg gcgcggaata ccgtcaaagt cactataagt catgccagcg ctagctttag
    55321 caattagagc cttattagca gcaagaacaa gagcataaat ctcacgttct tcatcagtaa
    55381 cttggccaat gtgaatggtc ctcgtcatat cactaacata gtgattgtag taacacccaa
    55441 agtccatggt caagctctct ttattctgga taaccttgtc actggcgcgt ccatgaggca
    55501 tggcagagcg atagcctgaa gctgcaatga tatcaaatga tgtgccgctg gcaccatact
    55561 gacgcatgcg aaaatctaaa aaattagcca ggtcacgttc agtggttgtc cctggtttaa
    55621 taaaatcaag agcatcttca aatgctttgt ctgagatcga gcacgcttta gcaatggtat
    55681 caatttcaga agtatcctta ataagacgta aatgttccac aaaacctgac tgggcaagta
    55741 aggttatccc tgacagttct gcttgcatgg cctgataaaa agaaaacgat acctggtcct
    55801 caaaaccaag gcaatctatt tgatcagcct ctaacaattc tgccacaacc ttaagcggcg
    55861 tgcggctttc gataatatca aatccctcaa cactagcttt agcaagcaag gtataacgtg
    55921 aatctgtgat caaaacacga cgcttggccg ttattaaaac agttgctgca gttccagaaa
    55981 aacctgtcaa gtaataacta ttggttaaat gggtgaccag aagagcctct agccccttct
    56041 ctgccatctg ccttaggcag tgacctaatc gttgctctaa aaatcctgac atcgcgaact
    56101 cctttggtaa cttttaagaa tattgtagaa tgaaaaaact actttaagtt taccatgatt
    56161 tgagagcatt taaaagatta aaaaggagct caaacgaact cctaatccta ttgttgtagt
    56221 tttactttca aataatgacc agtatagctt tctttaactt gagctacctc ttctggtgtc
    56281 cccgtagcaa caatctgacc acctccgaca ccaccttctg gtcctaagtc aataatatgg
    56341 tcagcagatt tgataacgtc caaattatgc tcaatcacaa gaaccgtatt gccatcgtct
    56401 acaaagcgtt ccaaaacttt taatagcctt gcaatatcat ctgtgtgtaa accagtcgtt
    56461 ggctcatcta ggatatacaa gctcttacct gtcgagcgtt tgtgcaattc actagctaat
    56521 ttcatccgct gcgcttctcc tccagataga gtagtagctg gttgacccaa ggtcacataa
    56581 cccaaaccaa catccttaat ggtttgaatt tttcgagcaa ttttagggat agcagagaaa
    56641 aataccaagg catcatcgac agtcatgtca agcacttcag caatattttt ttctttataa
    56701 tgcacctcaa gcgtctcaga attataccgt ctgccgtggc aaacctcaca aggcacataa
    56761 acatctggca aaaagtgcat ttcgattttg ataatcccat cacctgaaca agcctcacaa
    56821 cgcccacctt tgacattaaa agagaaacgg ccttttttgt agccacgaat cttagcttcg
    56881 ttggtttggg caaacaagtc tcgaatatca tcaaagacac ccgtataggt ggctggattt
    56941 gaccgtggcg tccttccaat cggactttgg tcaatgtcaa tcaagcgttc aatatgttca
    57001 ataccagaaa tagagtgata tttaccaggc ttatcagcat tacggtttaa tttttgggcg
    57061 acagcctttt tcaaaatact attaaccaag gttgatttcc ctgagcctga tacccctgtg
    57121 accgcaataa atttgccgag agggaatcta acatcaaggt gttgaagatt gttctgcgct
    57181 gctcctttta tttcaatgaa tcgcccatta ccagaacgac gctctaatgg cactggaatg
    57241 aattttttac cagacaaata ttgacccgtg atggattttt tattcttagc cacttgtttc
    57301 ggcgttccag aggcagtaat ttctccaccg aactcacctg cccccggtcc cacatcaatc
    57361 agccagtctg cctgcatcat ggtgtcttca tcgtgttcta ccacaattaa ggtattaccc
    57421 aaatcacgca tttttttcag gctttcgatc aaacggtcat tgtctctttg gtgcaatcca
    57481 atagaaggct catccaagat atagagcacc cctgataagt tagaaccaat ttgtgttgct
    57541 aacctgattc gttgactttc cccacctgat aaagtcccag cagcacgtga taaggtcaga
    57601 taattcagtc ccacattatt taagaatgtc agacggtcat ggatttcttt gacaatcggt
    57661 ttagcaatgg tactttcatt ttctgtgagt tccaattctt ccaacaactg caagtggtcg
    57721 gcaatcgata attctgaaat ttgaccaata tgaggtcctt cttcgccacc cacatgcaca
    57781 cacaaagctt ggtcattcaa acggtaacca tgacaagtcg cacaggtcaa ttcgttcata
    57841 taaccacgca tcacattgcg cgtataatca ctattagttt cgtgataacg gcgattaaca
    57901 ttagtcacaa caccttcaaa aggaatgtca atgttacgct caccaccaaa atcattcaca
    57961 tagtgaaaat gaaattctct atcacctgaa ccataaagca ctaaatctct ttcttcctca
    58021 gtcaaggcct caaaaggtgt atccatatcc accccaaaac ttgccatagc ttgctcaagc
    58081 atggttgggt aataattgga ggaaatagga ttccaaggcg ccaaagctcc ctctctcaaa
    58141 gacttacttg ggtcaggaac aaccaagtcc aaatccactt ccaacttaat gcctagccca
    58201 tcacaggtcg gacaagagcc gaacggcgca ttaaaagaga agagtcttgg ttctaattca
    58261 ggaaccgtaa atccacagac aggacaggaa taatgctcag aaaagagcag ttcattgcca
    58321 tccatagtgt caatcataag gtagccatct cccagcctta aagctgcttc aaccgaatca
    58381 aataaacggc tacgaatacc atccttatta accagacggt caataaccac ctcaatgttg
    58441 tgcatcttac ttttggacaa ctctggcact tctgtcacgt caaaaatatc cccgtcaacg
    58501 cgcacacgga catagccgtc tttttgaatt ttctcaaaaa ctgttttgtg ttgccccttc
    58561 ttccgacgaa caacaggagc taaaatctgc atgcgtgtcc gttcagggag ggctaagacc
    58621 tgctctacaa tttgttctgc agaagacgcc gtgatagcac catgcccatt gatacagtaa
    58681 ggtgtgccca cacgcgcata tagtagacgt aaataatcat tgatttccgt aaccgtacca
    58741 accgttgagc gagggttctt actggtggtt ttttggtcaa tggaaatagc agggctaaga
    58801 ccgtcaatgg aatccacatc tggtttttcc atattaccca agaactgtct agcataagct
    58861 gataaacttt ctacgtaacg acgttgccct tccgcataaa tagtatcaaa ggctagacta
    58921 gattttcctg accctgataa ccctgtcaca acaactaatt tgtctcgtgg aatttccacg
    58981 tcaatatttt ttaaattgtg ggcttttgcc ccatgaatta ttattttatt ttgcatcttg
    59041 aatgtgccta aaggcaccct cctcatcgag ctt
//
LOCUS       DATTYN010000009        56689 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.09, whole genome shotgun sequence.
ACCESSION   DATTYN010000009 DATTYN010000000
VERSION     DATTYN010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56689
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.09"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(71..907)
                     /locus_tag="VB649_000715"
     CDS             complement(71..907)
                     /locus_tag="VB649_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP1669682.1"
                     /translation="MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSIT
                     VGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKID
                     VIWNGYSITKERQEKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYD
                     ALLRTPKVLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLEN
                     YRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANI
                     KS"
     gene            complement(923..1552)
                     /locus_tag="VB649_000716"
     CDS             complement(923..1552)
                     /locus_tag="VB649_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP1669683.1"
                     /translation="MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLL
                     RMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTIT
                     MGKQKADAKEKALDLLTRLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEP
                     TSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK"
     gene            complement(1562..2203)
                     /locus_tag="VB649_000717"
     CDS             complement(1562..2203)
                     /locus_tag="VB649_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEP1669684.1"
                     /translation="MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKIPF
                     KPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEI
                     FRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ"
     gene            complement(2310..2645)
                     /locus_tag="VB649_000718"
     CDS             complement(2310..2645)
                     /locus_tag="VB649_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEP1669685.1"
                     /translation="MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVV
                     LDSNGVRLSDGDTITVIKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            complement(2845..4659)
                     /gene="glmS"
                     /locus_tag="VB649_000719"
     CDS             complement(2845..4659)
                     /gene="glmS"
                     /locus_tag="VB649_000719"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEP1669686.1"
                     /translation="MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNL
                     IKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVI
                     ENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFA
                     LMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKD
                     KVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETG
                     NVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNMLEQLTDTPVELGVASEWGYHMP
                     LLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAG
                     PEIAVASTKAYTAQIAALAFLAKAVGEANGKSEALDFDLVHELSLVAQSIEATLTEKD
                     VVAEKVEALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISL
                     IEEGTPVIGLISSSELVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPF
                     LAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            complement(4835..5392)
                     /gene="lepB"
                     /locus_tag="VB649_000720"
     CDS             complement(4835..5392)
                     /gene="lepB"
                     /locus_tag="VB649_000720"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEP1669687.1"
                     /translation="MVKRDFIRNILLLLIVIIGVILLRIFVFSTFKVTPATANAYLKN
                     GDLITIKKNIQPKYKDFVVYRVDKKDYVSRVVAVEGDSVTYMDDIFYLNNMVESQAYL
                     EKMKTRYLNNAPLGTLYTEDFTISTITGDKYQKVPKGKYLLLNDNRKNTNDSRRFGLI
                     NASQIKGLVTFRVLPLSDFGFVEVE"
     gene            complement(5558..7060)
                     /gene="pyk"
                     /locus_tag="VB649_000721"
     CDS             complement(5558..7060)
                     /gene="pyk"
                     /locus_tag="VB649_000721"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEP1669688.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADD
                     AKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
                     IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     KPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            complement(7123..8136)
                     /gene="pfkA"
                     /locus_tag="VB649_000722"
     CDS             complement(7123..8136)
                     /gene="pfkA"
                     /locus_tag="VB649_000722"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEP1669689.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVVSTIQYDFEHKGKNHHI
                     IVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVEL
                     LKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRS
                     LSQ"
     gene            complement(8216..11326)
                     /locus_tag="VB649_000723"
     CDS             complement(8216..11326)
                     /locus_tag="VB649_000723"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEP1669690.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLY
                     GAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKL
                     HMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRY
                     FAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTAFYQTHCPQALQNLEDLV
                     SGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLHELVIISDM
                     GFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGV
                     PEYELTNLTKKIGFKDSLVTVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIH
                     AAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEK
                     VAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVA
                     TTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGF
                     NRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIP
                     YTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLI
                     KIGLFDCFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEI
                     VGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLS
                     VNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKY
                     WLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFV
                     LKTVFR"
     gene            11511..11882
                     /locus_tag="VB649_000724"
     CDS             11511..11882
                     /locus_tag="VB649_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP1669691.1"
                     /translation="MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTK
                     MGFSHTEIIPVLTSFLKEDSQ"
     gene            11882..12580
                     /locus_tag="VB649_000725"
     CDS             11882..12580
                     /locus_tag="VB649_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669692.1"
                     /translation="MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKT
                     TLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFY
                     SDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDP
                     AARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEY
                     QQSIDSLFRETYKV"
     gene            12590..13375
                     /locus_tag="VB649_000726"
     CDS             12590..13375
                     /locus_tag="VB649_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669693.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSD
                     GLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSH
                     QIILSKLLASFICSVFNTIILAFAIAIVIVPMFNINELLEGFFNSFKMDYFINMLTVL
                     AYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHSHIFNIN
                     TSADSFPFTEQKTIYLLILEQFIEMIMFYLATNFIIKNKLNLQ"
     gene            complement(13502..14116)
                     /locus_tag="VB649_000727"
     CDS             complement(13502..14116)
                     /locus_tag="VB649_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEP1669694.1"
                     /translation="MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSN
                     ALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIII
                     GSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVM
                     ITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH"
     gene            14208..14555
                     /gene="ssrA"
                     /locus_tag="VB649_000728"
     tmRNA           14208..14555
                     /gene="ssrA"
                     /locus_tag="VB649_000728"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            14857..15477
                     /locus_tag="VB649_000729"
     CDS             14857..15477
                     /locus_tag="VB649_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEP1669695.1"
                     /translation="MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQ
                     AAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPSQHDPKTAGEVTIDAYTWQF
                     DQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYS
                     QASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE"
     gene            complement(15734..17998)
                     /gene="glgP"
                     /locus_tag="VB649_000730"
     CDS             complement(15734..17998)
                     /gene="glgP"
                     /locus_tag="VB649_000730"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEP1669696.1"
                     /translation="MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPH
                     LVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFA
                     DDKAVHAKLAEIKFNNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSR"
     gene            complement(18033..19526)
                     /gene="malQ"
                     /locus_tag="VB649_000731"
     CDS             complement(18033..19526)
                     /gene="malQ"
                     /locus_tag="VB649_000731"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEP1669697.1"
                     /translation="MNKRASGILMHISSLPGKFGIGTFGKSAFEFVDFLAETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDFELLVDDELLEAADLCDITFGTNPEAVDYA
                     QLFQVRRPLLEKAVRAFVAEQENVCKLEAFETASSWLTDFAEFMALKEYFNNKALQDW
                     DDETVIKRQEDSLNNYRELLAKKITYHKVCQYFFYQQWSALKTYANHKGIEIIGDMPI
                     YVSADSVEVWTMPELFKVDSDKKPLFIAGVPADGFSEDGQLWGNPTYNWSAHEKSNFA
                     WWIYRIQESFKLYDQLRIDHFKGFSDFWEIPAGDKTARNGHWASAPGIALFSAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDITSQSIDLPHYYDRNCVAYT
                     GTHDNEVVNGWYDNLSEEQVHFVNNYLHKHADESITKAMLRTIFASVCDTAILCIQDL
                     LDKDGKSRMNMPNTIGGNWQWRMLDGELNQDHKDYLIYLTDLYGRAR"
     gene            complement(19641..20660)
                     /locus_tag="VB649_000732"
     CDS             complement(19641..20660)
                     /locus_tag="VB649_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP1669698.1"
                     /translation="MVTIKDVAQKAGVNPSTVSRVLKDNRSISMKTKEKVRKAMADLG
                     YVPNVAAQILASGLTHNIGLVFPPITTSDRLSEPFFMEILSTITNEAKESHFTVSIAT
                     GISLDDLIEQVKLMHLQKRVDGFIILYSDQDDPVKKYLMTNNLPFIIVGAPQGDTNKT
                     TYIDNDNQLMAKTAVEHLYQKGHHNILFITDDLLSEVTSERYLGYLKGCFKRSLKTKP
                     MLLFDRKDPVSVEILMETISSFKATALVVVGDVLAIRMVQLLSFYDIKVPDDMSIITF
                     NNSNYAKLIHPYLTTFDINVENLGKMSFKQLLDIINSNEQNLSQTIFVPFSLKQRESV
                     RDISH"
     gene            20905..22152
                     /locus_tag="VB649_000733"
     CDS             20905..22152
                     /locus_tag="VB649_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP1669699.1"
                     /translation="MKSWQKVIVGGASLTLASTLLVGCGSGSKDKKEAGADSKTIKLW
                     VPTGSKKSYADTIAKFEKDSGYTVKVVESEDPKAQEKIKKDASTAADVFSLPHDQLGQ
                     LVESGTIQEVPEKYNKEIAATSTDQALVGAQYKGKTYAFPFGIESQVLFYNKSKLAAE
                     DVTSYDTITTKATFGGTFKQANTYATGPLFMSVGNTLFGENGEDVKGTNWGNEKGAAV
                     LKWIADQASNKGFVSLDANNVMSKFGDGSVASFESGPWDYEAAQKAIGKENLGVAIYP
                     KVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKTRN
                     IVPANKEVQSSEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDAFN
                     GKIKESDYLTKLQQFDKDIAATK"
     gene            22426..23787
                     /locus_tag="VB649_000734"
     CDS             22426..23787
                     /locus_tag="VB649_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP1669700.1"
                     /translation="MTQSNLTPNISVIEALKRGSWDIKLSSIIMGFANFANKQFIKGI
                     LFLISELIFLVAFVSQIIPAIRGLVTLGTQTQGMTTKTIDGINIQVAVDGDNSMLMLI
                     FGLASLIFCLVFAYIYWCNLKSARNLYLFKQKGQKIPSFKEDLATLTNGRFHMTLMAI
                     PLIGVLLFTILPLIYMICLAFTNFDHNHLPPKSLFDWVGLANFGNVLSGRMAGTFFPI
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKWKKMWRTIFVITIAVPQFISLLIMRN
                     LLNDEGPLNALLNKIGLINGSLPFLSDPLWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILLIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSEYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            23787..24623
                     /locus_tag="VB649_000735"
     CDS             23787..24623
                     /locus_tag="VB649_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP1669701.1"
                     /translation="MKNKRRFQLGLVYATLIILSIIWLFPIAWVILTSFRSEGTAYVN
                     YFIPKTFTLNHYINLFTNETFPFGKWFMNTLIVATFTCIISTFITVAIAYSLSRIKFK
                     FRNGFLKLALILNMFPGFMSMIAIYYILKALGLTQTLTALVLVYSSGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLAKPIIVYTALLAFMGPWIDFIFAQVILG
                     DATSKYTVAIGLFSMLQPDTINNWFMAFTAGSVLIAVPITLLFMFMQKYYVEGITGGS
                     VK"
     gene            24781..25578
                     /locus_tag="VB649_000736"
     CDS             24781..25578
                     /locus_tag="VB649_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP1669702.1"
                     /translation="MTSKITIKDIAREAGVSVATVSYVLNQRNDQKISEETRNKVLHI
                     SNLLNYTPNQAARSLVTQQSNSVVLYYKYADSILARAEQLHTISFLSRLLHEQDYQLV
                     CLNEDSIEKFDWADLILTLDVDNDTFYKIGKLNFKPLIAIDSFVNDPLFFQINTDYAA
                     LKDQANQFFKDEPYTLLSLPITNRERYEHVSSFFPSLHIVNDLRELTYFEKENLLLID
                     ESLDQFFVNSSQKLYCPRFSPKKGQVILEAIEWAKKRQPDKKHNLLV"
     gene            complement(25694..26509)
                     /locus_tag="VB649_000737"
     CDS             complement(25694..26509)
                     /locus_tag="VB649_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEP1669703.1"
                     /translation="MPDKKQFPISYISHCLSARAMFASRAQFTWWQNLLIIVFLNALI
                     MIPVTLHYANMTTYPLERIVTKSLSPITDKTYQALTQGKIEKDTFQGQSLIRRDGELV
                     LAVLPTKVDLEQLASESTRQIIVTKKEWRFVTPDGKELRAHVRGQQQSLADLTTVKAV
                     KDFVNQQWYDSNKASVLGFLLLTFVLMVCVGTLIVIGLGAFFLTLTKRSRLFMIRNFS
                     EGLGLMVNCLAWPSLLAIALSFFIQDPVLIMNCQVFGTLLMLTWVFYKTQFRD"
     gene            complement(26531..27391)
                     /locus_tag="VB649_000738"
     CDS             complement(26531..27391)
                     /locus_tag="VB649_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP1669704.1"
                     /translation="MRKTYVSISMKRKRFFTQLLTYLYLISLVIVILFPILVTVSSAF
                     RPGNTTAFSFHFDGPWTLSNFKTLFQDTLYLRWYWNTLIVAFFTMLIQVTVITLTGYA
                     YSRYNFFGRKKSLIFFLVVQMVPTMAALTAYFVMAWLFNALNQYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVLPLVRPMIAVQSLWAFMGPFGDF
                     MLAKFLLRAQENYTVAVGLQSFITNDARNPKVTLFAAGAILIAVPISVLFFFLQKNFV
                     SGLTSGGTKG"
     gene            complement(27388..28695)
                     /locus_tag="VB649_000739"
     CDS             complement(27388..28695)
                     /locus_tag="VB649_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP1669705.1"
                     /translation="MVDNQRQQKPNKAMWLSVIPGLGQLYNKQIVKGGVLLVVFFLEL
                     LEIVVLGIPALTGFYSLGSVPMQDHSLFMLIKGAMQLITLVLFGIFHLVAMRDAKLVA
                     HQMNEGKKVPVTAKETLEAIYEKGFPYLLIIPAYLAMAFAIIFPVLVTLLIAFTNYDF
                     RHIPPYRLLDWVGLKNFLNILELSTFKTAFTSVLSWTLIWTLAATSLQIVIGIATAVI
                     ANQSFIRGKRLFGVIFLLPWAVPAFISIMSFGNFFNDSIGAMNVQVLPFIEKFLPFVD
                     FGIVSWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQAIPADLYEAATVDGATVLQK
                     FRHITMPMIFAVAAPTFISQYTFNFNNFSIIYLFNNGGPGTVGGGAGTTDILISWIYK
                     LTTQTSPQFSMASAVTLIISVIVISVSLITFKKFKAFDMEERS"
     gene            complement(28770..30905)
                     /locus_tag="VB649_000740"
     CDS             complement(28770..30905)
                     /locus_tag="VB649_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclomaltodextrin glucanotransferase"
                     /protein_id="HEP1669706.1"
                     /translation="MRELHIKTYKLLTKSAVLLGLISFPLTVSAADNASVTNKADFST
                     DTIYQIVTDRFNDGNTSNNGKTDVFDKNDLKKYHGGDWQGIIAKIKDGYLTDMGISAI
                     WISSPVENIDSIDPSNGSAAYHGYWAKDFFKTNQHFGTEADFQQLVKVAHQHHIKVVI
                     DFAPNHTSTAEKEGTTFKEDGALYKNGKLVGKFSDDKDKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNINPKVDQYMKEAIDKWLDLGVDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFVFGEWFSGHTDDDYDMTTFANNSGMGLLDFRFANAIRQLYTGFSTFTMRDFYKVL
                     ENRDQVTNEVTDQVTFIDNHDMERFATKVANNQTAVNQAYALLLTSRGVPNIYYGTEQ
                     YATGDKDPNNRGDMPSFNKESQAYKVISKLAPLRKQNQALAYGTTEQRWISDHVLVFE
                     RKFGNHVALVAINRDQTNGYTITNAKTALPQNSYKDKLEGLLGGQELIVGADGTISSF
                     ELGAGQVAVWTYEGEDKTPQLGDVDASVGIAGNKITISGQGFGNSKGQVTFGEISAEI
                     LSWSDTLITLKVPTVPANYYNISVTTADKQTSNSYQAFEVLTDKQIPVRLLINDFKTV
                     PGEQLYLMGDVFEMGANDAKNAVGPLFNNTQTIAKYPNWFFDTHLPINKEIAVKLVKK
                     DSIGNVLWTSPETYSIKTGHEAQTITIKK"
     gene            complement(30931..32634)
                     /locus_tag="VB649_000741"
     CDS             complement(30931..32634)
                     /locus_tag="VB649_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEP1669707.1"
                     /translation="MNVAGMLHIPDSRYCFAISQKELVIRLRVAKEDRGITVNLVHGP
                     KYGYHEFQEELEMSVAYTDHTHAYYETTLTLDDVRLAYIFKIEEEGQTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQVIPWTKDAVFYQIFVDRFNRGDWEKGDSYVNMGW
                     LEKPTPKSFAGGDLKGITEKLDYLKDLGITVIYLTPIFQSISNHKYDISDYYAIDPQF
                     GTKYDLQELIDLAHQMGIKIILDAVFNHASSDAVEFQDVLRYGKESKFFDWFMTHDEH
                     PSMDLVNYETFAGCNYMPKWNTSNRDVQDYLIEIGRYWIKEFCIDGWRLDVSDEVSHD
                     FWRRFRQAVKAEKADAILIGENWHDAYPYLAGDQYDGIMNYAFTKACLDYFAFETMTS
                     KQLAEKLSNILMRNTWQVNRMNLNLLDSHDTHRFFTQVKGSKDKLLAALALLFIFMGI
                     PCLYYGTEVAMEGGYDPDSRRGFPWDDAERDKDFFSKVKAIIALRQQPALQEGAISID
                     YDEDCLILKRSLGEQSISLVLNNGESAYSIKEGGQILTSNGVTKNKKQLLQDGYIVFS
                     N"
     gene            complement(32800..34059)
                     /locus_tag="VB649_000742"
     CDS             complement(32800..34059)
                     /locus_tag="VB649_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP1669708.1"
                     /translation="MSWNWKKASVLGTLSLASVLPLTACVSGGGKGVKETDGKTIVVS
                     VDEGYVDYIKSIKGEFEKEHKVTVKVKKEGMMDTLDKLSTDGPTGASPDVFLAPFDRV
                     GGLGTEGQIAEVTLGNSKEFDDTVKKLVTIDGKTYGAPDVIETLVTYYNKDLVPQAPK
                     SFTELEVLQKDSKFAFASEPGKSVGFLAKWTDFYYGYGLIAGYGSYIFGDKGTKPSDL
                     GLGNDGTVEGLNYAKQWYGTWPQGMQDTKKAGDFITEQFISKKAGVIIDGPWAASSFK
                     DAGVNFGVMEIPTLTNGKKYQPFAGGKAWVISNYSKGKTTAQKFLDYVTNAENQKRFY
                     DKTQEIPANLTARNYASKEGNELTKAVISQFESAQPMPNIPEMAEVWEPGANMFFNVA
                     SGKEEASKAAKEAAKTIKEAIEQKYAE"
     gene            complement(34669..35652)
                     /locus_tag="VB649_000743"
     CDS             complement(34669..35652)
                     /locus_tag="VB649_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP1669709.1"
                     /translation="MVIIAVMIFFGVILGILIVEYGQKRSFSSWLVEKMFAYRKYKLS
                     KKVDNYKGVETQRNRNIPYHLDNPEEIVGFSTQEYDVNGMQVFIINDQKQSHQPVIYY
                     LYGSVYLRRPEKLHFKTVKHLIQLTNAKVVFPNFPKVPYATYQDVYPKLVEAYQQFCL
                     SNGPSQVSVIGDSSGGGMALAFAKYIRDTKTAPQPKQLILISPWLDVSFKNQAYKDFE
                     AEEAYLDARRLRDIGELWAGGQGNMQLPYVSPLYGDYEDLPEITTFVGTKEIFYPDIM
                     SLHDQLTRQRIANQLIIAEKMIHAYVIFPIREAKQARKQIAELVLKTVEHT"
     gene            complement(35683..36933)
                     /gene="dltD"
                     /locus_tag="VB649_000744"
     CDS             complement(35683..36933)
                     /gene="dltD"
                     /locus_tag="VB649_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEP1669710.1"
                     /translation="MLKRLWLILGPLLIAFVLVVITIFSFPTQLDHSIAQEKANAVAI
                     TDSSFKNGLIKRQALSDEICRFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSHYYGMQQITNEMQKKKAIFVVSPQWFTAQGINPSAVQMYLSNTQVIEFLLKA
                     RTDKESQFAAKRLLELNPGVSKSNLLKKVSKGKSLSRLDRAILKCQHQVALREESLFS
                     FLGKSTNYEKRILPRVKGLPKVFSYKQLNALATKRGQLATTNNRFGIKNTFYRKRIAP
                     KYNLYKNFQVNYSYLASPEYNDFQLLLSEFAKRKTDVLFVITPVNKAWADYTGLNQDK
                     YQAAVRKIKFQLKSQGFHRIADFSKDGGESYFMQDTIHLGWNGWLAFDKKVQPFLETK
                     QPVPNYKMNPYFYSKIWANRKDLQ"
     gene            complement(36926..37165)
                     /gene="dltC"
                     /locus_tag="VB649_000745"
     CDS             complement(36926..37165)
                     /gene="dltC"
                     /locus_tag="VB649_000745"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEP1669711.1"
                     /translation="MSIEETVIELFDRLFMEDVSEMMDEDLFDAGVLDSLGTVELIVE
                     LESTFNIKVPISEFGRDDWNTVTKIVQGVEELQHA"
     gene            complement(37183..38439)
                     /gene="dltB"
                     /locus_tag="VB649_000746"
     CDS             complement(37183..38439)
                     /gene="dltB"
                     /locus_tag="VB649_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEP1669712.1"
                     /translation="MMMFFSHIPYMEPYGNPIYFVYLILAFLPVIIGIFKQKRLSTYE
                     TLVSLVFILFMFGGDHYQQLVAFLFYLLWQIISVFAYQKYREKANSAGVFYLAIAMAL
                     FPLIWVKVAPLTGPSSQTLFSFLGISYLTFKSIGMIIEMRDGTLQEVRLPDFIRFMIF
                     FPTFSSGPIDRFRRFQEDYHKLPERDDYFAMLNKAVMYLMLGFLYKHIISYCLGGILL
                     PLLENKALMVGGYFNKETILVMYVYGLNLFFDFAGYSMFAIGISYLLGIRTPENFNMP
                     FLSASLKDFWNRWHMSLSFWFRDYVFMRLVHLLIKHKTFKNRNVTSGVAYLVNMLVMG
                     FWHGLTWYYIAYGLFHGIGLIINDAWIRKKKEINRHRKKKGLSPLFQSRAFHVLCIVV
                     TFHVVMFSLLLFSGFLNDLWFNRPLH"
     gene            complement(38436..39974)
                     /gene="dltA"
                     /locus_tag="VB649_000747"
     CDS             complement(38436..39974)
                     /gene="dltA"
                     /locus_tag="VB649_000747"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEP1669713.1"
                     /translation="MIKDMIDSIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAF
                     IDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPS
                     LIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPK
                     GVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELT
                     VSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYI
                     IDEDGKELSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTED
                     NILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIV
                     VKDGVRERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINE
                     VNNR"
     gene            complement(39986..40129)
                     /locus_tag="VB649_000748"
     CDS             complement(39986..40129)
                     /locus_tag="VB649_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEP1669714.1"
                     /translation="MIKNKSRMRGIAVFIGKTILFYLILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            complement(40393..42384)
                     /gene="uvrB"
                     /locus_tag="VB649_000749"
     CDS             complement(40393..42384)
                     /gene="uvrB"
                     /locus_tag="VB649_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEP1669715.1"
                     /translation="MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFR
                     VEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQL
                     QLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFF
                     PEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARD
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQ
                     RAIDETARRREIQVAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRG
                     ERREAINALQKQMQEAAELLDFELAAQMRDLILELKLMD"
     gene            42577..44751
                     /locus_tag="VB649_000750"
     CDS             42577..44751
                     /locus_tag="VB649_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEP1669716.1"
                     /translation="MTHKIKVLLLAIMSIFLTCNIASAETIAIVSDTAYAPFEFKDSD
                     QIYKGIDVDIINEVAKRQSWDFSMSFPGFDAAVNAVQSGQASALMAGTTITNARKKVF
                     HFSEPYYDTKIVIATRKANAIKKYSDLKGKTVGVKNGTAAQAFLNNYKKKYDYTVKTF
                     DTGDLMYNSLSAGSIAAVMDDEAVIQYAISQNQDIAINMKGEPIGSFGFAVKKGSGYD
                     YLVNDFNTALKAMKADGTYQAIMTKWLGTDDKATTSQATGNPSAKATPIKDSYKIVSD
                     SSFAPFEFQNGKGKYVGIDIELIKAIAKQQGFKIEIANPGFDAALNAVQSSQADGVIA
                     GATITDARKAIFDFSDPYYTSNIILAVKAGKNIKNYEDLDRKTVGAKNGTSSYSWLKE
                     NAPKYGYNVKAFDDGSSMYDSLNSGSVDAIMDDEAVLKYAISQGRRFETPLEGISTGE
                     VGFAVKKGTNPELIEMFNNGLAALKKSGQYDDIIDKYLDSKKAATPSEKGADESTISG
                     LLSNNYKQLLAGLGTTLSLTLISFAIAIIIGIIFGMMAVSPTKSLRLISTVFVDVVRG
                     IPLMIVAAFIFWGVPNLIESMTGHQSPINDFLAATIALSLNGGAYIAEIVRGGIEAVP
                     AGQMEASRSLGLSYGTTMRKVILPQAVKLMLPNFINQFVISLKDTTIVSAIGLVELFQ
                     TGKIIIARNYQSFRMYAILAIIYLIMITLLTRLAKRLEKRLN"
     gene            44751..45491
                     /locus_tag="VB649_000751"
     CDS             44751..45491
                     /locus_tag="VB649_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP1669717.1"
                     /translation="MTELKIDVQDLHKSYGQNEVLKGIDAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLETITSGKVVVDGFELSDPKTNIDKARENIGMVFQHFNLFPHMTVLENI
                     IFAPVELGKESKEVAKKHGMALLEKVGLSDKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(45639..45791)
                     /locus_tag="VB649_000752"
     CDS             complement(45639..45791)
                     /locus_tag="VB649_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669718.1"
                     /translation="MTEKNGATFLMAVGFFLIAISPMVGNKYLHIVTGLALTGLGYYL
                     TKHKRP"
     gene            complement(45839..47167)
                     /locus_tag="VB649_000753"
     CDS             complement(45839..47167)
                     /locus_tag="VB649_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP1669719.1"
                     /translation="MSHFSDKFMEISGKIGSQRHLVAIRDSFISMMSITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAKAMQPVIDINGYVYFGTIGIMALFFAFAFGYNLAVMHKINP
                     LAGGLISFGSFIATLPQTLTISTPLENASANLISNLKEMGLSVVTAGGASSIETSQWG
                     AIALKYVGATGLFTALIIGFLSSFVYAALTKRNIAITLPDNVPPAVNKAFAAIIPGTV
                     AIYASAIFAYLIFALTGSSLSDVISTYIQLPLLGLSQGIGSVILLTFLVQLLWFFGLH
                     GHNVLAPVMDGIYMVALTENTAAYNTAHSAANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFVIPWLIVPPICASIA
                     YFATAIGLIPPVFLSVPWITPVGLYAYLATGGNIMAGLVSLFNLFVAFLI"
     gene            complement(47345..47794)
                     /locus_tag="VB649_000754"
     CDS             complement(47345..47794)
                     /locus_tag="VB649_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEP1669720.1"
                     /translation="MIISAEGDVSIHHCFEAMLISLQEDYRQNTLRQLSRDDIKAGIN
                     YVKHYGKYKERTVRVLITALEAPQLYTACFSSNHGIKELAYRLEALGENRTRITYSYD
                     YHPLDIFQKANHFIVGKLFKKSLERQSQAQLAALIQYAKQLQQPSSL"
     gene            complement(47791..48126)
                     /locus_tag="VB649_000755"
     CDS             complement(47791..48126)
                     /locus_tag="VB649_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP1669721.1"
                     /translation="MTEPSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEEAQHLLQ
                     EATNSLNIAHKSQTHLLSQEAAGDAVELSLLMVHGQDHMMTALAFIDLAKELVTVYDK
                     MSAIQRGES"
     gene            complement(48129..48440)
                     /locus_tag="VB649_000756"
     CDS             complement(48129..48440)
                     /locus_tag="VB649_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP1669722.1"
                     /translation="MKSIMLVCNAGMSTSMLVTKMQKAAQARDLEVSIWAVPVSEADN
                     EVAANSIDVLLLGPQVKFLLKDFKDKFEPDIKVDAINMADYGLMNGEKVLETALAMME
                     E"
     gene            complement(48463..50457)
                     /locus_tag="VB649_000757"
     CDS             complement(48463..50457)
                     /locus_tag="VB649_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEP1669723.1"
                     /translation="MLSKKELAIITFLIHHKEQFVSSATLAEVIGMSDRTVRKYLKEL
                     ISSLPEHGAHIISKQGRGYCLEIDHSMAFDIFWQESVTSKKRLADVTQVEESVDREDY
                     VLHKFFFEDAVQDFEELCQELYISRTTLKHVLAGIKERIIPYQLELEITHQHIQIRGK
                     EEDIRHFIMDYFFVTSFDNTLSTMVGNTFLEGINFAEIMIIVLDECRDAKLKLSDFVM
                     NNLVLHIALMVQRIRSGCPLELFSIPIAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVGKHWQDDNTDEKLQDHLKACIAKISQLTGMTLETDTNLFQGLLTH
                     MMPLTTRLENHIQLTNPLTEEIKSQYPEIFTLTKQTFSDLLVCQKNDVSDDEWAYISL
                     HLMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRLRIVDVISYYEITEER
                     LKTVDLIISSISLANLMFLTPVITVSVFLSNQDIETIRQFIGEQEGIKKEVSLPSQMS
                     LAKAEQLLTGVFSPNLFLYLDEKISKEDLLLRMIACLDEAGTETFVEDFYHQMVLREN
                     YSPVIYGEVLAFPHPANPMTYSEQVVVAICREPLEWDKAHQAVHFVFLLSPSKGHNHR
                     LKYVSPGLASFVNQVELQQALLEEPNYSKFMTVFTPLIHD"
     gene            complement(50563..51657)
                     /locus_tag="VB649_000758"
     CDS             complement(50563..51657)
                     /locus_tag="VB649_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEP1669724.1"
                     /translation="MVDLGFSLYPGRYDVTKSKAYIDLCHSHGAKRLFMSLLQLAPAD
                     HQMFHCYAELIAYANQLGIRVIADVSPSFISQAGWSDQLIERAHAFGLAGLRLDEALP
                     LAEIVTLTRNPFGLKIELNMSTDKQLLMSLLATDAERSNIIGCHNFYPHEFTGLSWQH
                     FKDMSRFYHEHDIETAAFISAQSASESPWLLAEGLPTVEDHRHLPIGLQVELMKAIGT
                     IDNILISNQFISEEELAACTQALARPVTTIKVRPIIDLTEVEEQIIGYPHCYRGDVSD
                     YVIRSTMPRLVYAQESIAPRDQSKEVKRGSIIIDNDRYHRYKGELQIALKNFTVSSKA
                     NVVAEVREDYLSLLDDLRPWQEFCLEIAPS"
     gene            complement(51666..53066)
                     /locus_tag="VB649_000759"
     CDS             complement(51666..53066)
                     /locus_tag="VB649_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP1669725.1"
                     /translation="MKQRKHRYQFPDGFLWGSSTSGPQSEGTVPGDGKGPSNWGYWFS
                     IESAKFHHQIGPEKTSTFYENYKGDIALLKETGHTIFRTSIQWSRLIPEGVGEVNPKA
                     VTFYREVFQDIIAQGIKLIVNLYHFDLPYALQEKGGWENKATVWAYETYAKTCFELFG
                     DLVNTWITFNEPIVPVECGYLGYYHYPCKVDAKAAVQVAYNTQLASSLAVKACHKLHP
                     DHKISIVLNMSPAYPRSDAPEDVKAARIAELFQTKSFLDPSVLGVYPAELVSILEEAD
                     LLPQYSADELEIIKNNTVDFLGVNYYQPLRVQAPSKSQQEGDPLILDIYFEPYDMPGK
                     KVNPHRGWEIYKPGLYDIALNLKEHYGNIEWLVTENGMGVEGEEAFLADGQIQDDYRI
                     TFIEDHLIQLHKALGEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLESQKRTIKK
                     SGYWFKALSESNGFDK"
     gene            53291..53986
                     /locus_tag="VB649_000760"
     CDS             53291..53986
                     /locus_tag="VB649_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEP1669726.1"
                     /translation="MAYLNYFTKTEWALWLSSVLAILISALLFGKQAPLALIASLIGV
                     TSLIFSAKANPIGQGLVIIFSIIYAYLSLRNSYYGELMTYLFMTLPMTIFSLFTWLNH
                     PFEGKKSQVTISRLTPTDRRCLFVFTILITLIFYGILASIQTAYLLVSTLSIATSFSA
                     VYLSYKRSPYFALAYGLNDLVLILLWMHAAQTDASQYAVVICFATFLINDSYTFYNWL
                     MLQRYQEKKVKKG"
     gene            complement(53991..54149)
                     /locus_tag="VB649_000761"
     CDS             complement(53991..54149)
                     /locus_tag="VB649_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669727.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     EKLKKDEA"
     gene            complement(54218..55531)
                     /gene="obgE"
                     /locus_tag="VB649_000762"
     CDS             complement(54218..55531)
                     /gene="obgE"
                     /locus_tag="VB649_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEP1669728.1"
                     /translation="MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAET
                     GKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLME
                     RPQIIVANKMDMPEAQENLKAFKEKLAAQYDEFDDLPMIFPISSLAHQGLDNLLEATA
                     ELLAKTDEFLLYDESDLVDEEAYYGFAEAEKDFEITRDDDATWVLSGEKLERLFVMTN
                     MERDESIMKFARQLRGMGVDEALRERGAKDGDPVRIGKFEFEFVD"
     gene            complement(55588..55716)
                     /locus_tag="VB649_000763"
     CDS             complement(55588..55716)
                     /locus_tag="VB649_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEP1669729.1"
                     /translation="MAFGENGPRKKTTFEKVTMFVVILMVLVTVGGLIASALSVLM"
     gene            56068..56689
                     /locus_tag="VB649_000764"
                     /pseudo
     CDS             56068..56689
                     /locus_tag="VB649_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        17786 a        11603 c         9685 g        17615 t
ORIGIN      
        1 tattaaatcg tctagctgac tttgtctgct agatctcacc tgttaaacaa aaaaaggaca
       61 agtgtccttt ttaagattta atattggcag tggcaacatc atctccaaac catttctcag
      121 aaatagcttg aaatttgcca ttttgataaa gcaccctgaa agcacgatta atttttgctt
      181 gcaacgtttt gtcttctttt ctaagtccaa ccgaaaatgc ttcattttca aaggtcgttg
      241 ggatcatccg ataattctcc aattgccctt cttttgctaa atagtaattg gcatatactt
      301 tgtcaatcaa tattccatcg atacgatctg attttaaatc aataaaagct tgtgtaaagg
      361 tttcatattg attagcgtct ttatttttaa taaaatcttt cagcacttta ggagttctta
      421 acaaggcgtc ataacctgat gaagctgatt gtgctcctaa cactttatgt ttcatatctg
      481 atattgtttt aatatcagat ctttttttga caacaataat ttgttcattt ctcatgtaag
      541 aatcagtaaa ggcaaccttt tcctgacgct ccttagttat tgaataacca ttccagatta
      601 catcaatttt accattgttt agttctgctt ctttcatgtc ccaattaata gcttgaaagt
      661 taaccttgag tccatattgg tgaaaaactt ctttagccaa atcaatatca aaacctttgc
      721 atttgccgct ttcatcctta tagcccatag gaacaaacgt attgtcaaaa ccaactgtaa
      781 tacttttttg cttttggtaa actccccaag catctcctga tttaagactt ttagtagctt
      841 gacaagctac caagaaaaag ctactagcta tggctaaaat tgctacggtt ctttttttta
      901 taatcatctt ttgggtcctc ttctatttag gattaaccct aataatacga tctgagatgg
      961 cttcggcaaa aacaagatcg tgagtgacta caatttgagt tattcccatt tcacggtttt
     1021 gaacaatcaa ggcttctacc gtctgacgta attcaggatc tagggcactg gtcggttcat
     1081 cgtaaccgat aatttgagga tcaatcatca tggctctcgc caaagcaacc cgttgttttt
     1141 gacctccaga taacgaatag ggataaactt gggcatgttc ttttaatcct aaacgtgtca
     1201 gtaaatccaa agccttttct ttagcgtcag ccttttgctt gcccattgta attgttggag
     1261 acagcgttag gttgtctaaa acggtaagat gaggaaacaa ttgaaaatct tggaaaacaa
     1321 atccaagcaa gttacgattt tccaaatgat caataccgac atcttctcca ttgtaaaaga
     1381 cttgacctga atcaatagat tcaagaccag ccaacatccg taagagtgtt gtcttaccgc
     1441 cacctgatgg acctaccaaa gagagcactt ctccgtcttg aacggttaga ttaaagccat
     1501 caaaaatggt tttttgacca aactgtttgg aaatattttt gagttctaac atgaagcctc
     1561 cttactgata ataattaaac cgtttttcaa cttgttttga aataatcgtg accagtccaa
     1621 ttaaaagcaa atagataaga ccagcgataa acataggggc taaggttgca tccctattgg
     1681 ctgccgtctt acttgctaat aaaagatctc ctacaccgag tacatagaca agggaagaat
     1741 ctttgaccaa attaatgact tcattgaaaa cacttggtaa cacaatttta aacacttgag
     1801 gcaaaataat ataccgaatg gtttgaagag gttttaactt taatacttta gctgcttcat
     1861 attgaccttt tggaatagcc tcaatcccac ctctaaaaat ttcagcaaag taggcagcat
     1921 aattcaaagt aaacgccaaa atagcagctg gcattcgatc aaaactaatc cccacacttg
     1981 gcaaaacata atagaaaaaa atcaattgaa gtagtaatgg tgtccctcgc atcatccaca
     2041 cgtatagggt taaaaaccac tgtagcggtt taaagggaat cttcatcaag aaagctaaaa
     2101 tagcccctaa ggggatagaa agaatgataa caataaagaa tacttgtaag gtcaccaagg
     2161 caccatctaa taagctgggt aaaacttgct gaatataggt catgttgcct cctaaaactg
     2221 aatattttac tattatacca aatttgaacg tatttgggga gagatttttt tataaaaata
     2281 caaccagatc agctggttgc gtattattat tagattttct tgacaaattc tgatttcaat
     2341 ttcatcgcac caaacccatc aatcttacaa tcaatgttat gatcaccttc caccaggcga
     2401 atatttttaa cacgagtccc ttgtttcagg tcttttggag cacctttaac ttttaaatct
     2461 ttaataacag taatagtatc gccatcagac aatcgaacac cattgctatc taaaacaaca
     2521 agtccttctt cttcagtcgc ttcttcgcct ggtgtccatt caaaagcaca cattggacag
     2581 attaataaaa gaccatcttc gtaaacatat tcagactggc attgcaaaca atttggtaat
     2641 gacattttgc tctcctaaaa aatttcttaa tggtaacatt ttactttaga atgctggttt
     2701 tgacaagttg aatacgttat catatttgct ttttctgtcc tcaaataagg cttcatttcc
     2761 ctttttcctg ccttgatgat gatgattaga taaaaaaata aggcaatcac tagctagtga
     2821 ctaccttatc atggttcccc ctcattactc cactgtaaca gccttagcta gattacgcgg
     2881 tttatcaacg tcaagtccac gttgtaatga agcgtagtaa gcaatcagtt gagttggaat
     2941 taccatagca attggcgcca agaaaggatg aaccttattg acaataatgt catctccctc
     3001 acggtcaagc ccttcttcca caacggttaa aacatgagcc ccacgagcag caacttcttg
     3061 aatattacca cgcgtatgag aagcaaccaa ctcactagat gaaattaaac caatgactgg
     3121 agttccctct tcaattaaag aaatggtgcc atgtttcaat tcaccagccg caaagccctc
     3181 gcattgaata taagaaatct cttttaattt caaagcagct tccatcgcaa cgtaataatc
     3241 attaccacgc ccgatgtaaa aagcattacg agtagtagct aacaaagctt ctactttttc
     3301 tgctacaacg tctttttctg tcaaagtcgc ttcgatagat tgagctacta atgacaactc
     3361 atgaaccaaa tcaaagtcaa gagcttctga cttaccattc gcctcaccaa ctgccttagc
     3421 taaaaaggca agggcagcaa tttgtgcagt gtaagctttt gtagacgcaa cagcaatttc
     3481 aggtccagca tgaatcaaca tggtgtatgt tgcttcacgt gacaaagttg atcctggaac
     3541 gttagttact gtcaaactcg gaatacccat agcatttgcc tttactaaaa cttgacgact
     3601 atctgcggtt tctcctgatt ggcttagtag aataaacatt ggtttcttgc taagcagagg
     3661 catgtggtaa ccccactcag aagccactcc caactcaact ggtgtatctg tcaattgctc
     3721 aagcatattt tttgttgcaa aaccagcatg gtaggaagtc cctgccgcta aaatataaag
     3781 acggtcagcc tcttggatag aggtaatgat agctggatca acctgtacgt taccagtttc
     3841 atctgcataa gttgaaatta attgacgcat tacggttggt tgctcatcaa tttctttcag
     3901 catatagaaa ggataagtcc ctttgccaat atcagataag tctaattcag cagtgtagga
     3961 atctcgtatc agctctttac catcgtagtc tgtaacagtt accttatctt tggttaaaat
     4021 aactagctcc ttatcatgaa tttccataaa ttcactggtt tcacgaatca tggccatggc
     4081 atctgaacaa accatgttgt aaccttcacc aagtccaatc aacaatggag acttgttttt
     4141 agccacataa atagtatcag ttgcttggct atccattaac gcaaaggcgt aggaaccttc
     4201 aataatgctt aaagcttttt taaaagcttc cagtactgac aacttgtctt cttccacaaa
     4261 ttttccaatc aagtgtactg caatctcagt atctgtctgc cccttaaaat catgtccagc
     4321 taggaactct gttttaatgt gaaggtaatt ttcaatcaca ccattatgaa caagtacaaa
     4381 acgtccagtt tgtgacgtgt gaggatgggc attatcctct gttgattggc catgcgttgc
     4441 ccaacgggtg tgaccaatcc ctgttgaacc agcaacatca atgccaatct tggcacgcaa
     4501 atcagcaatc cgccccactg atttaatcaa gtttgtttga ttggcattag ccacaaaaat
     4561 tcctgctgaa tcataacccc ggtattcaag cttttcaagg ccttgcatta aaatatccgt
     4621 tgcattgcga tttccaacaa ctccaacaat tccacacatc ttaattacct taacaagttc
     4681 gttaacttgc tactttctct cataatttca ataattggta tagtcatatt ataccgataa
     4741 aaacagtatg tttacagtat ataatatcca caatgtcttg tcaaacataa aattggtata
     4801 gtctaattat aaaaaaagta gagtagcctg acaactactc tacttctaca aatccaaaat
     4861 cgctgagagg caaaactcta aaggtcacta aacctttaat ctgcgaggca tttattaacc
     4921 caaagcgacg actgtcattc gtatttttcc ggttatcatt tagaagaaga tattttcctt
     4981 taggaacctt ttgatactta tcaccagtaa tagttgaaat tgtaaaatct tcagtgtata
     5041 aagttccaag aggagcgtta ttcaagtaac gtgtcttcat cttttcaaga taggcttgtg
     5101 attccaccat attattgagg taaaaaatat catccatata ggtgacacta tctccctcga
     5161 cagcaacaac acggctcaca taatcctttt tatcaaccct gtaaaccaca aaatctttgt
     5221 atttaggttg aatgtttttc ttaatagtga ttaaatcacc attcttcaaa taagcattgg
     5281 ccgttgctgg ggtcacttta aaggttgaga aaacaaaaat tctcaacaaa atgacgccaa
     5341 taatcacaat taataacaat aatatatttc ttataaaatc tcgctttacc atattaactc
     5401 ctagtctatt ctcttattat accatgttat agaccagaaa aaaagcagac aatttctaag
     5461 ataaaagagt atgcattgtt agggtaacat ttctcttcca ataaaaaaga ggttagaaga
     5521 aaactcttct aatcctcgat cagttacttt aataaactta ttttacagta cgaacacgca
     5581 ttgtgtttgt tccaccagta ccaactggaa cacctgcaac gataacaatg ttatcaccag
     5641 attgaaccaa accagtttca agagccacac gttctgctac ttcaaacatg tcatcagtag
     5701 atgcaggttt ttcagcaaga actggaataa caccccagtt aatcatcaat gcacgttgta
     5761 ctttttcatc aaatgttaca gctaagatat ccgcatctgg acggaattta gaaatcgcac
     5821 gtgcagtatt accagtttcg gtaattgtaa ccacaagttt gatgtccatt gaatgagttg
     5881 catctttaac cgctgaagca attacatcag ttttgtttgt acgtgggaat gcagatgaat
     5941 ctaaacgacc atattcgtta agaagagttt gtgcattacg atcaatagtc gccattgtac
     6001 gaacagattc aactgggtat ttaccattag ctgactctcc tgaaagcatt gttgcatcag
     6061 taccatcgat aacagcattg aagacgtcag atacttcaga gcgtgtcgca cgtggttttt
     6121 cagtcattgt ttcaagcatg tttgttgctg tgataactgc tttaccagct gcattcactt
     6181 tagtgataat cattttttgg aaaactggaa ccatttcaaa tggtacttcg atacccatgt
     6241 cgccacgtgc aatcatgata ccatcagcag cttcgatgat ttcatcaaga ttatcgatac
     6301 cttgttggtt ttcaatctta gcaaataatt gaacatggtc gttaccagtt tcgcgacaga
     6361 tttcacgaac ttcctcaacg tctttggctg tacgaacaaa tgagattgca ataaagttaa
     6421 gtccttgttc aagaccaaaa cggatatcag cattgtcgcg ttccgcaagt gctgggaaag
     6481 gaattttagt gttagggata ttaacacctt tttgtttagc aataataccg tcgttttcta
     6541 cttcaacaat aaattgacgt gttgcgatat ctttgtcgat cactttcaaa ccaagcttac
     6601 catcatcgat aagaatagta tgacctactt ctacttcatc gtagatatca aggctaccag
     6661 caacgttcaa agcaataaca tcgcgagttg attgaatacc ttgtgtagtc gctacacgga
     6721 ttttttctcc agtaacatag ctgaactctt tagcatcgtc tgcaaacaat tccgtacgca
     6781 tttcaggacc tttagtatcc aaaaggaaac caactttttg acgagcaatt tcttctgcaa
     6841 ggcggacagt tgccatacgg tcaccttgtt ctttgtggtc accgtgtgag aaattgaaac
     6901 ggaaaacatt cgcaccagct tcaattaatt cagcgatttt ttttgctgat tcttcaacat
     6961 caagttgacc agcccagtag ccatcttctc catatttttt accaccacgg atttcaaccg
     7021 caggaccaag tgttgcaacg atttttacgc gtttattcat tttactctga aactccctta
     7081 tttttttgtc aataattgac gatttaacaa ttttaactaa acttattgtg acaatgaacg
     7141 gttcaaagct gcaaagtcta aacgagcttt gtgtggatta ttaacaataa tcttgccttc
     7201 ttcagtcaag ctgaacaaag caccttcttc tgcagtacca aggattgggc tttcaacaag
     7261 ttcttcatta tgaataccaa cagccaagcc acctttgcct tctttaagta gctcaacagc
     7321 atgtgaaccc atccaagaag caatgacacg gtcacgagca gttggtgaac ccccacgaag
     7381 aatgtggcca agatttgtca cacgaaggtc actcttatcg ccagcttctt taagtttttg
     7441 agcaaaagct tcaccactca taacaccttc agctaagacg atgatgtggt gatttttacc
     7501 tttgtgttca aaatcatatt ggattgttga taccactttt tcaatatcaa actcttcttc
     7561 tggaacaatg atttgatcag caccactagc aatacctgcc caaagagcaa tatcacccgc
     7621 attgcgaccc atcacttcaa ccacaaaagt acgtccgtga cttgatgagg tgtcacgaag
     7681 tttatcaata gcttcaactg ctgtgttaac tgctgtatca aatccgatag tgtagtcagt
     7741 tcccgcaata tcgttatcga ttgttcctgg gatacctacc gctgggaagc cgtgctctgt
     7801 caagcgcata gcgccatgat aagaaccatc cccaccaata acaacaacac cctcaatacc
     7861 atgtttttta agttgctcaa taccagccaa ttgaccttca agttgagcaa actctggata
     7921 acgagctgag tataagaaag ttccaccacg tgagatttta tcaccaactt cttttgaacc
     7981 cagtgggaaa atgtcgccat caaccatacc tgcatagcca cggttgatac cataaacttc
     8041 cattccttct gaaattgctt tacgaacgac tgcacgaata gcagcgttca taccaggagc
     8101 gtcgccgcca ctggttaaaa cagcaatacg tttcattttc tggtactcct ttaattaatt
     8161 taacggtctt attatagcat attcatttgc aaaatacttc actaattgtc catttttatc
     8221 gaaaaaccgt tttcagaaca aaaggacgaa gtttttcctt taaattctct gttacatgaa
     8281 cctgaatctt agttaatgca attgtttcct tatttttttg atagtgaata acaactggag
     8341 tcgttcctgg aaaggcacct aaaatctcag aaatttggga atcaaactga tggttttcaa
     8401 ctaataacca atatttttga ctaatagcca tttgcacttg ctgacacacc atctgcagtc
     8461 gatggtctct ttcttttatt ctacctttta agtaatagaa ttctccttct tttaattggt
     8521 ctttataaat ggcatactct tgtggaaaaa gtgtgacatc gagctttttc ttagtgtcat
     8581 tcacacttaa aaaagccatt tgctgcccac ttgttttggt tctaatgatc ctaatgctat
     8641 ctatttgaat cagtacgact gcttcgcttt ctttgactaa ctgtgaaatg ggagtaaaag
     8701 tttgggtact tttctcagca atatcaatta aaggatgctt gctcatgcca accccaacga
     8761 tctcctgttc caaagaatat ttttcagttg ctgagtaatc tttcgtatct acccaactaa
     8821 aggaagaatc tgaaaaaaga gaaccaagct cattaacaaa taccagtaaa ccatccaaat
     8881 tgtccagaat ttttttacgg ttaggctcaa agcaatcaaa cagacctatt tttatcagag
     8941 gctcaaggaa aacctttttt tgatattttt ctggagttct agtgagaaaa tcctctacgc
     9001 tattaaatgg tctttgctcg ataatccaat aagcaaaatc ccttggcaac cccttaatat
     9061 ttttcagccc catgtaaatc ttgctagctt caattttatc agtgtaagga atactattaa
     9121 tggtaacttg cgctacttga aaatctgatt ctagagcatc tgtgatatag tcactgctag
     9181 aataattcat catgatatcg taaaaaacag ccgggtaatg ggctttgaaa taagccaatt
     9241 gaaaagctaa agctgaatag gcaaaggcat ggctgcggtt aaaaccataa cctgcaaatt
     9301 tttccatccg tttaaaaagt cctctagctg tttcttcagc tctccctagg tgcttagcag
     9361 aagcaataaa gtcttcttcc attttttgca tttcttgtag atttttttta gacatggcac
     9421 gccttaacaa gtcggccttg cctaacgtaa aaccagcata aacctgtgca atctgcataa
     9481 cttgttcttg ataaagcata ataccgtaag ttggctctaa aatgggagca atcacaggat
     9541 caatcaaatc aattttttct tgtccttctc ttcgtttaat gaaattagtg gtatagtcac
     9601 ttgcccctgg tctatttaga ctggtagtgg caacaatttc ttcaaaacgt tgtggcttaa
     9661 tccgttttaa aagattaata gcaccatttt gttcaaattg gaaaattccc ttggtatccc
     9721 ctttagcaaa aagtgccaac gtttgcgggt cttctaaatc aatggctgca atatcaatct
     9781 gacacccgta gtctttagca accttctctt gcattttttg aacaaaggtc aaatttctta
     9841 accccaaaaa atccattttt aacaggccgt tagcttcgac cgcatgagca tcatactggg
     9901 tgatcatcat gtcatcgccc gattttagag gaatatgatt ggtcaaggta tcatcactca
     9961 tcacaatacc agctgcgtga atggacgttt gtcttggatt tccttcgata cgcttggcaa
    10021 tagcaaaggc cttttgaaat tcagttctac tattaataac ctgcctaaaa gagattgact
    10081 tttcatagac agtaaccaag ctatctttaa aaccaatttt tttagtgaga ttggtcagtt
    10141 cgtattctgg aaccccgaac cgtttgaaaa catcacgaat agcctgttta gggccaaagg
    10201 ttgaaaaggt cacaatttgc gccgaatggt cgctaccata acgatttcgg acataccgta
    10261 gaaattctga acggtaaata tctggaagat cgatatcaat atcaggcatg ctataacgtt
    10321 ctttgtttaa aaagcgctca aatagcaaat catgttgaac tggatcaatc cctgtaatgt
    10381 tcagagcata agccactaga ctacctgccg ccgagccacg tcccataccc atataatagc
    10441 ctttactgcg tccaaagcga agtaaatccc acacaatcaa aaaataatca tcaaagccca
    10501 tgtcagaaat aatgaccaat tcatgtagta agcgcgattg ataaggctct ttccacaatc
    10561 ctttttcctt caaaccagcc tcagtcaagt cttgcaattc ttgcttggca gacttatctc
    10621 tattaaaatg aggcaatttt aaatttgtat cgaaatcata atagattcct gacactaagt
    10681 cttctaaatt ctgtagagct tgagggcagt gtgtttgata gaaggcggtt agttgttgac
    10741 aatctgctaa ctcttgatca ctttctacca caggggtctc tgccagactg aggttatctc
    10801 gaatggcatg caacatgtgc agggtttcca tatcatcttg cgcaaaataa cgaactgtcc
    10861 ttaggggtat aagctgcctc ttagaatcca tatgagataa atcagtatac tgatcaacac
    10921 cgatatagta gtcaaaaggg accactaatg tatcgctcca acccttacta ggaataataa
    10981 ccgctatccc ttccaaatgt tggcagaggt aatccatatg aagcttgcca gacatttttg
    11041 ccgtggaaat ttttaaaagc tgatgatagc cttgtgtatt ctgggcgatt aagttaagga
    11101 gcacctgccg ctcttgatag agaatctcta cttccaaacc taaaactggc tgcagtccat
    11161 ttttttgaca acctttaata aaatggtaag caccataaag attatcctta tccatgattc
    11221 ctatggtgtg gtaaccaaat tgctttgctc gttcaaaata atgatttaag tcaattaaac
    11281 tatccataaa tgagtataca gttttagtat caagttgagc aaacataagt tcctcctttg
    11341 gttatcttgt tccctattat actatgaaaa aggttttctt gcttcaattt tctctctaat
    11401 ctacgtctac ttctcaaaga gtgaaaaatg gcataaaact tgacattccc cttttttttc
    11461 tgtaccattt aattagtaca aatatctata ttactcagaa aggagaccac atgtcttgga
    11521 aatttgatga aaaatctcct atttatgcgc agatagcaca acatgtcatg atgcaaatta
    11581 ttagccaaga aatcaagagt ggtgatcaac ttccaactgt tcgtgaatat gcagaaatcg
    11641 caggtgttaa tcctaacacc atgcaacgag cgtttacaga acttgaacgg gaaggaatgg
    11701 tttattcgca acgtactgct ggccgttttg taactgacga tcaaaaatta attgctcgta
    11761 aaagacgaga gttagcaatt agtgaattag aatcatttat caccaatatg acaaaaatgg
    11821 gatttagtca cactgagatt atccctgttt tgacgagctt tttaaaggag gattcacaat
    11881 aatggcacac ctattgcaac tacatcatgt ttcaaaatct taccgtgaaa aaaaagctat
    11941 tgatgactta accattacta tcccgaacgg taaaattatc ggattattag gtccaaatgg
    12001 aagtggtaaa acaactttaa ttaaactcat taatggcctt ttacaaccaa ataaaggaga
    12061 aattgtcatt gatggctacc gtccctgtgt tgagacaaaa aaaattattt cttatttacc
    12121 agatactact tatctcaatg aaaatatgag aattaaggac atgttggagt tctttagtga
    12181 tttttacagc gactttgaca aatccaaagc aacaagcctt ctaagagatt tagaactaga
    12241 ccctgaagac cgcttcaaaa ctctatccaa aggaaacaaa gaaaaagtac aattaattct
    12301 tgtgatgagt cgtaaagcca gactctatgt acttgatgaa cctattggtg gagttgaccc
    12361 tgctgcaaga gactacatcc taaaaaccat cattaatagt tattgtgaaa atgcttctgt
    12421 tattatctca acccacttga tttcggacat tgaacctatc cttgacgaag tcattttctt
    12481 gaaacaagga agacttttct tatctggcaa tgctgatgac ctaagacaag aataccagca
    12541 atccattgat tccctcttta gggaaactta taaggtttag gaggatatca tgtttggaaa
    12601 attattaaaa tacgaattta gatctattgg aaaatggtac tttgcgctta atgctttcgt
    12661 tattgccatc gctgccattt tgtcatttac gataaaactg tttgctcaaa gcaatagtga
    12721 tggactattt ggagtactaa ccaataagat gttgcctctg acattaggtt taacttttgg
    12781 ctccctgatc gctggttccc tcttatcaac attacttatc attatcaaac gttttagcaa
    12841 aagtgttttt ggacgggaag gatacttaac gttgacttta cccgtcaatt cgcatcaaat
    12901 tattttatca aaactactag cttcttttat ttgcagtgtt ttcaatacta tcatccttgc
    12961 atttgctatc gctattgtaa ttgtaccaat gtttaacatc aacgaactat tagaaggatt
    13021 ctttaatagt tttaagatgg attatttcat caatatgcta actgtactag cctatgtcct
    13081 attatcaaca tttacgagta tcttattaat ttatctttcc atttctatag gtcaactttt
    13141 ttctaatcgg cgaggcttga tggcctttat tgcatatttt atattagtta ttctgattag
    13201 cgttgctgca acatatgttc acagtcacat ctttaatatt aatacaagtg ccgatagttt
    13261 cccatttact gagcaaaaaa caatttatct tcttattttg gaacaattta ttgaaatgat
    13321 aatgttttac ctcgccacta attttattat caaaaataaa ctcaacctac agtaagcgtt
    13381 aagactttct tttaaactat gacacactat agtttaaaag aaagtctttt tcagtgttca
    13441 tagtaaataa aaaaaccgtc ttccatcaaa tagaagcggt ttatcaaatt aacaccaaac
    13501 cttaatgctg taagaaccaa gatataacat cttttccaaa aataaataaa taactgtagc
    13561 cgataataga aattggttta gttattaaaa gaatagttac aaagcgcttt aaagacatgt
    13621 ccgtcaatcc cgtaatcata accataatat cagctggaga aacaggcgat gccatacaaa
    13681 aaataaataa tttttcatat cctggtgtct ccaaacgcct ttcatacttg taaaatgttt
    13741 tgtcatttac aaagagtaag ataaatttac gaccataagt cttaacaagt aagaagagga
    13801 ctatactgcc aataatgatg cctacataat tataaataaa acctgttaca gggccaaaga
    13861 ttaaaaaacc tgcaactgtc gtaaggcctc caggaatcac aggaaaaaca atctgtatga
    13921 tctgcacgac aataaaaaca aacggccccc ataatctata gcgctgcact aagtctttaa
    13981 gagcattact atcgtttaat atacctagtc tatacagcca aaaagcgagg aaaaaagtac
    14041 caattagtgc aataattcct aaaattttga taattttttg ccataatata taggcttttg
    14101 aattacgttt tgtcatagac taatcatacc ataagctgta aaattttgct atttaaaaaa
    14161 agttttgata gaatagttag tgtaagaaat tggttaatta tctatttggg gttgttacgg
    14221 attcgacagg cattatgagg catgttttgc gtcccatcgg cagatgtaaa ttgccagtta
    14281 aatataactg caaaaaatac aaactcttac gctttagctg cctaaaaacc agctagcgtg
    14341 acttctacaa gattgcttgt gtcctgttag aagtctcaaa atagcaagct acggttacga
    14401 aattgtctag tttcgtgaca agagattgat agactcgcaa actaatggct tgagttatgt
    14461 gtctttagtt tgttaaatga agacataacc tatggacgta gacaaatatg ttggcaggtg
    14521 tttggacgtg ggttcgactc ccaccagctc catcaatgct taccgtaagt aatcataact
    14581 tactaaaacc ttgttacatc aaggtttttt ctttttgtct tgttcatgag tttccgttat
    14641 ccctatagcc gtaccatcac gcttaccgat actccatcaa taccactcaa aaccttgtca
    14701 tatcagagct ttttgaccat ttttttcatg aatatctaaa aaaaagaatc aaaatagtac
    14761 taaattcccc atagcgcatg cgctatgggg aatcatagct atatcttgtt tataatttat
    14821 gatataatac agcaaaaata gtttaggaaa taacatatga caaaaaaaca cttactaaca
    14881 cttcttctca tctctttttt tactagcttt ttggtagctt gttcaacaac gaaagataaa
    14941 gagcctcaac cgtctgattc agaaatcatt actccccgac tacaccaagc cgctcatcaa
    15001 gataaacgcg ctaactttga aaaaattaaa cttgcgactg ttgattcctc atttacagga
    15061 gggacaagcc ttgaagaact tatttcactc tttggagagc ctagccaaca tgatccaaaa
    15121 acagcaggcg aagtaacaat cgacgcttat acttggcagt ttgatcaagt tactctcact
    15181 gttaatcttt atcaaaatag tagtattgtt aaaactatct ctaattttac ctttgcaaga
    15241 gagttaggct tatcgcaaaa ggaataccaa caattacaaa aaggaatgtc ttatgaagac
    15301 gttaaaaaga tcttaacaga acctgataat tatagccaag cgtcatctag tgatcatcaa
    15361 actttgcaag cgatttgggt tagtggctta aagacagata caagcggagc taatatttct
    15421 ctcgtttttg aaaataatca gttaacagaa atgtctcagg taggacttga agaataaaaa
    15481 atgcgtaata tattttgcta aaaagattga tttcgatgta caccgaaatc aatcttttta
    15541 tatcatttta ataaaaaact ttagtgtaat ttcttataat tgccttcata gatcgataaa
    15601 cagacttgtt ttacgcttaa tgtaataatt aatctaagtc tgaagaaaaa tcataagaca
    15661 gcagaaacta ctgtcttata atttagttta agcatgttac ggtaccgcta ccccacattg
    15721 caattattat tttttatcgt gaatgccaaa tatcttcgtt atactgctca atggtacggt
    15781 cagatgagaa gaatccagct tttgcgatgt tatggaccac ttttgtcatc cataaatctt
    15841 ggtcttcata gtctgctaac attttttctt tcacttcaat gtactcttca aggtcaatca
    15901 aagtcatgaa ccagtctttt gaaatcaatt ctttataaag acgatcaaga cgttcttcgt
    15961 tgccaaatgc tagcaattct ggactgataa taaagttcac tgctgcttta atagcagggt
    16021 ggttatcata gtaatctttt gctacataag aagcagtcgc ataaaggttg atgatggtgt
    16081 cagaatcttt accaaaggta tagatattct ccatgcctgc aagctcagcg atttctacgt
    16141 tagcaccgtc cattgtacca agtgttaaag caccgttaag catgaatttc atattaccag
    16201 ttccagaagc ttctttggat gctagtgaaa tttgctcaga aatatcagtt gctggaatca
    16261 agtgctctgc tactgtcacg ttgtaatttt caactagatg cacattaagg tatgggctta
    16321 cttcagggtc attgttaatc aattcagaca agcaaaggat caagtgaatg atgtcttgag
    16381 caatgatgta agcaggcgct gctttacctc caaagataac agtgatttta cgttttggaa
    16441 ggttgccttt tttaatttcc aaatatttgt gaatcacgta aagagcattc atctgttgac
    16501 gtttgtactc gtggaaacgt ttgatttggg tatcaataat agaatgttca tcaagctcaa
    16561 tgtctttatt gtctttaagg taacgtttaa gagctaattt gttgttgaat ttgatttcag
    16621 ccaatttagc atgaacagct ttgtcatctg caaaggccat caatttttct aattttgttg
    16681 cgtcagtcaa gtactcatcg ccaataagtt ctttaatgta atcagccaag tcttggttag
    16741 caaattctag ccaacgacgg aaagtaatcc cgttggtttt gttgttgaat ttttctgggt
    16801 aaaggtcata gaaagctttt aattcgctgt ttttcaatat ttctgtgtgg agtgctgcta
    16861 ccccattgac acttgttgca aaatgaatat ccatatgggc catgtgcaca cgacctgatt
    16921 cgtcaataat ttgaacagct gggtcagaca cttctgaacg aacaagagca tccaattttt
    16981 caatgatggt taccaagtgt ggcactactt cgtttaagta agcagttggc catttttcaa
    17041 gggcttctgc aagaatagtg tggttagtgt aaccaaccat atttttcaca acagctaccg
    17101 cttcatcaaa gtcaaagcca tgtttttcag tcaagagacg aattaattct gggatgacca
    17161 ttgacgggtg agtgtcattt atttgcacgt aagcgtagtc tgcaaggtca tgaaggtttg
    17221 aaccacgttc gatagcttca tcaatgatta attgcgctgc atttgacacc ataaagtact
    17281 gttggtaaat acggagcaat tccccatttt tgtcagaatc gtctgggtag aggaacaagg
    17341 tcaagttttt agcaatttgc gttttatcaa atgaaatacc gtctttgatt aacccgtaat
    17401 caacgccctc gatatcaaac aagttaaggt agtttttagt gtcgcgtttg taacccaaaa
    17461 catcaatacg atcgagacga gatttcaagg tgaagttctt aaaaggcaca tcgtaagaaa
    17521 tgtctgttgg aaccaaccat gagtcatctt caatccagaa gtttggctct gcttcttgtt
    17581 cattgtgttt gaagacttgc ttaaacaacc cacaatgata gtttaaacca accccttcac
    17641 cattaatccc aagagatgca atagagtcaa tgaaacatga agcaaggcgt cctaaaccac
    17701 cattacctag tgatggttct aattcaacat cttcgacttc tgcgatagat ttgccagcag
    17761 ctgccaattc ttctttgata tctttataaa ttcctaggtt aatcaggttg tttgatagta
    17821 atttaccaat caaaaattcc gctgagatat agtaaacttt gcgtttggca gtatttttag
    17881 ctttgtggct agcttcttct ttgacaaagt ttaataatga tagataaatc tcttcattgc
    17941 tagcctgcgt aagtgatttt cctagtttag tttcaacata ttctgtaaag cgtgtcatgt
    18001 cttcctcttt tcaataatgt aacatttaaa tattatcttg cgcgaccata aagatctgtt
    18061 aaataaataa ggtaatcttt gtgatcttgg ttcaattcac cgtcaagcat acgccattgc
    18121 caattacctc caattgtatt tggcatattc atacgactct taccatcttt atctaataaa
    18181 tcttggatgc aaagaatggc tgtatcacaa acagaagcaa agattgttct tagcatggct
    18241 tttgtaatac tttcatctgc atgtttgtga agatagttat ttacaaagtg tacttgttct
    18301 tcactaagat tgtcatacca tccgttaacc acctcgttat catgagtccc tgtgtaagcg
    18361 acacaattac ggtcatagta atgtggtaaa tctatacttt gactcgttat atcaaataaa
    18421 ccaaattcta atatcttcat gccaggaaag cctgttgatg ctaatagctg ctctgctttt
    18481 tcatcaatat aaccaaggtt ttctgcgatg ataggaagct ctcctaaggc ctcacgaacc
    18541 gcagaaaata atgctatacc tggggctgag gcccaatggc catttctagc agttttatca
    18601 ccagcaggaa tttcccaaaa atctgagaag cctttaaaat gatcgattct tagctgatca
    18661 tatagtttga aactttcttg aatacgataa atccaccatg caaaattaga cttttcatga
    18721 gcagaccaat tgtaggttgg atttccccac agctgaccat cttcactaaa gccatctgct
    18781 ggtacacctg caataaacaa tggcttttta tcactatcta ctttaaatag ctcaggcatc
    18841 gtccaaactt ctacactgtc cgcagaaaca taaataggca tatcaccaat aatttctatc
    18901 cctttatggt tagcgtaagt tttcaaggct gaccattgtt ggtaaaagaa gtattgacag
    18961 actttatgat aggtaatctt ttttgcaagc aactcacggt aattattaag tgagtcttct
    19021 tggcgtttaa tgacagtttc gtcgtcccaa tcttgtaagg ctttattgtt aaaatattct
    19081 tttaaagcca taaattcagc aaaatcagtt aaccagctag aagctgtttc aaaagcttct
    19141 aatttacaca cattttcttg ttcagcaaca aaagctctca ctgctttttc taaaagtgga
    19201 cgcctaactt gaaaaagctg agcatagtct actgcttcag gatttgtgcc gaatgtaata
    19261 tcacacaaat ctgctgcttc taaaagttca tcatctacta gcaattcaaa atcaatgaaa
    19321 tgtgtgttcc cagcaatagc tgaaaatgac tgataaggag aatctccaaa actcgtcgtt
    19381 gttaaaggca gaatttgcca ataggtttgt ttcgtctctg ctagaaaatc aacaaattca
    19441 aaagctgatt ttccaaaagt gcctatccca aatttcccag gcagggaact aatatgcatt
    19501 aagataccgc ttgcacgttt gttcatgatt tttctccttg tgaaatctat tcatgatgag
    19561 attataacgc aagcgcttgc gtaagtcaac cagtttccta aaaaaagtaa cattccttaa
    19621 aaatgctact ttttttgttc ttaatgacta atatcacgga cgctttctct ttgttttaaa
    19681 ctaaaaggaa caaaaatagt ctgactaaga ttctgttcat tggaattgat aatatcaagt
    19741 aattgcttaa aagacatttt tccaagattt tcaacattta tatcaaatgt cgttaaataa
    19801 gggtgaatta atttagcata attagaatta ttaaaagtga taattgacat atcatctggc
    19861 acttttatat cataaaaaga taataactgt accatacgaa tagccagaac atcaccaaca
    19921 acaaccaagg cagttgcttt aaaggaagat atagtttcca tcaatatttc tacgctaaca
    19981 ggatccttac gatcaaataa cagcattggc tttgttttta aagatcgctt aaaacaaccc
    20041 ttcaaatagc caagataacg ctcagaagtt acttctgata gtaaatcatc tgttataaat
    20101 aatatgttgt gatggccttt ttgataaagg tgttctactg ctgttttagc cattagctga
    20161 ttatcattat caatataagt ggttttatta gtgtcacctt gtggagcacc tacaatgata
    20221 aatggtaagt tatttgtcat caaatatttt ttgacaggat catcttgatc agaataaaga
    20281 ataataaaac catcaactcg tttttgaaga tgcatcagtt tcacttgctc tatcaggtca
    20341 tcaagagata tacctgtagc aatcgacaca gtaaaatgag attctttagc ttcgttagta
    20401 atagtcgaca aaatttccat aaagaaaggt tcacttaatc tatcgctagt tgtaatagga
    20461 ggaaaaacaa gtcctatatt gtgtgtcaaa ccactcgcta gaatctgtgc tgcgacattt
    20521 ggaacatatc ccaaatctgc catcgctttt ctaaccttct cttttgtttt catagaaata
    20581 gatcgattat cttttaatac cctactcacc gtcgaagggt taacacctgc cttttgagcg
    20641 acatctttta ttgttaccat atttacctcg ttactatatt taccaaagat aaaccttatc
    20701 atgggtttgt catgtatttc gtttccatta tacaattatc tttcaaaaaa tcaacttcaa
    20761 tcaagattcc cttgtcattt taactcaaat tctctaaact atttttttaa aaaaacgacc
    20821 ttttttttaa aaaaaggctt gactttttct gcaagcggtt gcataatatt aagtgtaaga
    20881 aatatatctt aggaggaaat agctatgaaa tcatggcaaa aagttatcgt cggcggagca
    20941 agtttgacac ttgcaagtac cttgttagtg ggatgtggat caggttcaaa agataaaaag
    21001 gaagctggcg ctgactcaaa gactattaaa ctttgggtac cgactggctc taaaaaatca
    21061 tatgcagata ccattgcaaa atttgaaaaa gattctggtt acaccgttaa agtggttgaa
    21121 tcagaagatc caaaagcaca agaaaaaatc aaaaaagatg cctcaactgc tgccgatgtc
    21181 ttttcacttc ctcatgatca acttggtcaa cttgtagaat ctggtactat tcaagaagtt
    21241 ccagaaaagt acaataaaga aattgctgct acttctactg atcaggcgct cgtcggtgca
    21301 cagtacaaag ggaaaacata tgctttccca tttggtattg aatcacaagt tcttttctac
    21361 aataaatcaa aattagctgc tgaagacgtt acttcatatg atacaattac tacaaaagca
    21421 acttttggtg gtacctttaa acaagctaac acttacgcta ctggtccatt attcatgtca
    21481 gttggtaaca ctttatttgg ggaaaacggt gaagatgtaa aaggtactaa ctggggcaat
    21541 gaaaaaggcg ctgctgttct taaatggatc gcagaccaag cttcaaataa aggttttgtt
    21601 agcttagatg ctaacaacgt tatgtctaaa tttggtgacg gttcagtagc ttcttttgaa
    21661 tcaggaccgt gggactatga agctgctcaa aaagctatcg gtaaagaaaa ccttggtgtt
    21721 gctatttatc caaaagtaac tattggaggc gaaacggttc aacaaaaagc attcttgggt
    21781 gtaaaacttt acgcagtcaa ccaagcacca gctaaaggtg atacaaaacg tatcgcagct
    21841 agctacaaat tggcatccta cttgactaat gctgaaagcc aagaaaacca attcaagact
    21901 cgtaacattg tcccagccaa caaagaagtt caatcttcag aagctgttca atcaaacgaa
    21961 cttgctaaaa ccgttatcac tatgggttct tcttcagact acactgtcgt aatgccaaaa
    22021 cttagccaaa tgggcacatt ctggactgaa agtgctgcta ttcttagtga tgccttcaac
    22081 ggtaaaatca aagaaagcga ctaccttact aagttgcaac aattcgacaa agatatcgct
    22141 gcaacaaaat aatatgattt catgtcatca ctgctatact aaaacaagca caaggtaagt
    22201 acttctaaaa agttctttcc acttacctta tgaagagtgg aactaggctc catcacattt
    22261 tattcaagct tagtctcact cttacttgtt tttgttttac tagtagctta gtgctactta
    22321 aatttttaac tctttaaaag tttacgtaac acttagctat ttcatcctaa caagagattg
    22381 aatctgaact accactctag tatcctaaaa taaaggagaa tctatatgac tcagtcaaac
    22441 ttgacaccaa atatatctgt aatagaagcc ttaaaaagag gcagttggga tattaaactt
    22501 tcgagtatta tcatgggatt tgccaacttt gctaacaaac agtttatcaa aggaatctta
    22561 tttttaataa gtgaacttat ctttctagta gcttttgtct cccaaatcat ccctgctatc
    22621 cgtggccttg tcactcttgg tactcaaact cagggaatga ctacaaaaac tattgatggg
    22681 attaacatcc aagttgctgt tgatggcgat aactctatgt taatgcttat ttttggttta
    22741 gcatcactca ttttctgcct agtctttgct tacatttact ggtgtaatct caaaagtgct
    22801 cgtaaccttt atcttttcaa acaaaaaggt cagaagatac caagcttcaa agaagatctt
    22861 gccacactta caaatggtcg ctttcatatg actttaatgg ctatcccact gattggtgtg
    22921 cttttattca ccattcttcc tttgatttac atgatctgtt tggcctttac caattttgat
    22981 cataatcact tgcctccaaa atctttattt gattgggtgg gacttgctaa ctttggaaat
    23041 gttttaagcg gccgtatggc aggaaccttt tttcctatct tctcatggac tttgatttgg
    23101 gctgtttttg ccacagtaac taatttcttc tttggtatta ttcttgcttt gttaatcaat
    23161 accaaaggat taaagtggaa aaaaatgtgg cgaaccatct ttgttatcac cattgcagtt
    23221 ccacaattca tctcattatt gattatgcgg aacttactca atgacgaagg cccactaaat
    23281 gctcttctca ataaaatcgg cttgattaat ggctcactgc catttttatc tgatcctctt
    23341 tgggcaaaat tctcaatcat ttttgtcaac atgtggatcg gtattccatt taccatgttg
    23401 attgcgactg gtattatcat gaaccttcca agtgaacaaa ttgaggctgc tgaaattgat
    23461 ggcgctagca aattccaagt cttcaagtct atcacattcc ctcaaattct cttgatcatg
    23521 acaccaaact tgattcaaca atttatcgga aatatcaata actttaacgt catttacctc
    23581 cttactggtg gtggtccaac aaattcagaa tactatcagg caggaacaac agacttgctg
    23641 gtcacttggc tctataaatt aaccgtcaca gctgctgact acaatttagc ttctgttatc
    23701 ggtatcttaa tctttacagt ttcagctatc tttagcttac ttgcttatac aaggacagca
    23761 tcctacaagg aaggagcggc taaataatga aaaacaaacg tcgatttcaa cttggacttg
    23821 tttatgctac tttaatcatc ctctcaatca tttggctctt cccaatcgct tgggttattc
    23881 ttactagctt ccgtagcgaa ggaactgctt acgtcaatta ttttattcct aagactttta
    23941 cattaaatca ctacattaat ctttttacta atgaaacctt tccttttgga aaatggttta
    24001 tgaatactct tattgtagcc acttttacat gtattatttc aaccttcata actgttgcca
    24061 tagcctactc tcttagccga attaagttta agtttcgcaa tggcttttta aaactagccc
    24121 ttattttaaa tatgttccct ggtttcatga gcatgattgc catctactat atcttaaagg
    24181 ccttaggttt gacgcaaacc ctaacagcac ttgtccttgt ttattcctca ggtgcagccc
    24241 ttggttttta cattgcaaaa ggattttttg ataccattcc ttattcactt gatgaatcag
    24301 ctatgattga tggcgctact cgtatggata ttttctttaa aataaccctt cctttagcaa
    24361 aaccaatcat tgtctatact gcccttcttg cttttatggg gccttggatt gactttatct
    24421 ttgcacaagt tatcttaggt gatgctacaa gtaaatatac cgttgctatt ggactatttt
    24481 caatgcttca gccagatacc attaacaact ggtttatggc cttcactgct ggttctgtct
    24541 taattgccgt cccaatcact ctcctcttca tgtttatgca aaaatactat gttgaaggca
    24601 tcacaggtgg ttctgttaaa taagttacaa cataccaaac cttctaaggg caagcccttt
    24661 aggaggtttt tgataaataa ggccgtagat aatcatatta gtcctcacat ttatcttcag
    24721 atcagccaaa tgtattaatg attccttgac ttttaccatg aattcggata taacaaaatg
    24781 atgacatcta aaattaccat taaagatatt gcacgagaag ccggggtttc tgtggcgacc
    24841 gtatcttacg tgttaaacca gcgcaatgat caaaaaatca gcgaagaaac ccgcaataaa
    24901 gtgctacata ttagtaacct tcttaactat acacctaatc aggcagccag gtcattagtc
    24961 acacaacaat caaacagtgt tgtcctgtat tacaaatatg cagatagcat tttagctagg
    25021 gctgaacaac tgcataccat tagctttcta tcccgcctat tgcatgagca ggactatcag
    25081 ctggtttgcc taaatgaaga tagcattgaa aaatttgact gggcagacct tattctgacc
    25141 ttggacgttg ataatgatac cttttacaaa attggaaagc ttaatttcaa acccttaatt
    25201 gccattgata gctttgttaa tgatcccctc ttctttcaaa ttaatacaga ttatgctgct
    25261 ctcaaagatc aggctaatca gttttttaag gatgaacctt ataccctgct ttccttgcct
    25321 atcactaatc gtgagcgata tgagcatgtt tcttccttct ttccaagttt gcacattgta
    25381 aacgacctaa gagagctaac ctactttgaa aaggaaaatc ttttactcat tgatgagagt
    25441 ttggatcaat tctttgtgaa ctcttcgcaa aaactctact gcccacgttt ttccccaaaa
    25501 aaagggcaag ttatcttaga ggccatcgaa tgggccaaaa aacgccagcc tgataaaaaa
    25561 cataaccttc tggtgtaacg cctgagaatt aacctatctt gactaattcc ttgtaactca
    25621 aaaccttgcc tctttagata aagaagcaag gttttttgat gtctaatcta ataacagggc
    25681 ctgacttgtc tcatcaatct ctaaactgtg ttttgtagaa cacccaggtc agcattaata
    25741 aggtaccaaa tacttggcaa ttcataatca gtactggatc ctgaataaag aaactaagag
    25801 caatcgccag tagactcggc caagccaaac aattaaccat caatccaagt ccttcagaga
    25861 agtttcgaat cataaatagc cgtgatcgtt tagtcagagt caaaaagaaa gcgcctagac
    25921 caatcacaat aagggtaccc acacacacca tgagaacaaa cgtcagcaaa agaaaaccaa
    25981 gtacactggc tttattactg tcataccatt gctgattgac aaagtccttc actgctttaa
    26041 ctgttgtcag gtcagcgagt gactgctgct ggcctctaac gtgagcacgg agttccttgc
    26101 catcaggggt aacaaaacgc cattcttttt ttgtcacaat aatttgtctg gttgattctg
    26161 atgccaattg ctctaaatcg acctttgtcg gtaaaacagc caaaaccaat tcaccatctc
    26221 gtcgaatcag agattgaccc tgaaacgtat ctttctcaat ctttccttgg gtcaatgctt
    26281 gataggtttt gtctgtgata ggcgacaaac tcttagttac aatccgttcc aagggatacg
    26341 ttgtcatgtt agcatagtgt aacgtaactg gaatcattat taaggcgttc aaaaaaacaa
    26401 taataagaag attttgccac caagtaaact gagctcggct ggcaaacatt gccctagcag
    26461 aaaggcaatg tgaaatgtaa gaaataggaa attgtttttt atctggcatt aaacattact
    26521 ccttgtcagg ttaccctttg gtaccaccac ttgttaaacc ggaaacgaaa tttttctgta
    26581 ggaagaaaaa gagaactgaa ataggcactg caatcagaat agctcccgca gcaaataagg
    26641 ttaccttggg atttctagca tcattcgtaa taaacgattg aagaccaact gctaccgtat
    26701 aattttcttg cgcccttaaa aggaatttag ccaacatgaa gtctccgaaa ggacccataa
    26761 aagcccataa ggattgtact gcaatcattg gtcgcacaag aggaaggaca atttggtaga
    26821 aggtcctaaa gtgtccagaa ccatctaact tagcagattc gtccaagtca taaggtaccg
    26881 tgtcaaaata acccttcatc aaccaggcat tcataggaat accaccaccg acgtaaatca
    26941 aaatcaagaa ccagtattgg tttaaggcat taaagagcca cgccataaca aagtaagccg
    27001 ttaaagccgc catggtagga accatctgta cgactaggaa aaagattaaa ctttttttgc
    27061 gtccaaagaa attgtaacgg ctatacgcat aacctgtcaa agtgatgact gttacttgta
    27121 tgagcatggt gaagaatgcc acgatcaagg tattccaata ccatcttaag tataaggtat
    27181 cttgaaagag tgttttaaag ttagacaagg tccatggccc atcaaaatga aaactaaagg
    27241 ctgtggtatt tcctggtcta aaagctgaac tgaccgtcac tagtattggg aataaaatca
    27301 cgatcactaa ggagattaga tagagataag tcaataattg ggtgaagaaa cgtttgcgtt
    27361 tcatggatat tgaaacatag gtctttctca tgatctctcc tccatatcaa aagctttaaa
    27421 tttcttaaag gtaatcaacg ataccgaaat cactattaca gagatgatta aggtcactgc
    27481 cgacgccatc gaaaactgag gcgaggtttg tgtggtcaac ttgtaaatcc aagaaatcag
    27541 aatatcagtt gtcccagctc cgccccccac agtaccaggg cccccattat taaacagata
    27601 aataatagag aaattattga agttaaaggt gtactgagag ataaaggttg gtgctgcaac
    27661 cgcaaaaatc attggcatgg tgatatggcg gaatttctgt aagactgtcg caccatcaac
    27721 ggttgctgct tcgtataaat cagctggaat tgcctgtaaa atacctgata ccaaaatata
    27781 gatataggga aatcctagcc aaccttgcac cataataaca gccacttttg tccagaaggg
    27841 gtctgtcttc caggacacaa ttccgaagtc aacgaaagga aggaatttct cgatgaaagg
    27901 aagaacctga acattcatgg ccccaatgga atcattaaag aaattaccaa aactcataat
    27961 agagataaat gctggaacag cccatggtaa caagaatatc acaccaaaga gacgttttcc
    28021 tctgataaag gattgattag caataacagc cgttgcaatt ccaataacaa tttgaagact
    28081 tgtcgctgct aatgtccaga tcagcgtcca tgacaaaaca gatgtaaatg ctgttttgaa
    28141 ggtgcttaat tctaagatat taagaaaatt cttcaaccct acccaatcca ataaacgata
    28201 cggaggaata tgcctaaaat cgtaattggt aaaagcaatc agcaaggtca ctaaaactgg
    28261 aaaaataata gcgaaagcca ttgctaaata agccggaatg atgagcaagt aaggaaatcc
    28321 tttttcataa atcgcttcaa gggtctcttt agccgtcacc ggaaccttct tgccttcatt
    28381 catttgatgt gcaactaatt tagcatctct catagcaacc aaatgaaaaa taccaaataa
    28441 gactagagta attaattgca tggccccctt aattaacata aataaggagt gatcttgcat
    28501 tggaacactt ccaagactgt aaaaacctgt taaagcagga attcctagaa ctacaatttc
    28561 tagtagttct aggaagaaaa caactaataa gactccccct ttaacgattt gtttattgta
    28621 tagttgtccc aaacctggga taacagatag ccacatggct ttattaggct tctgttgtct
    28681 ttggttatct accatttttt attcctcttc tcataaatga tttaaggtta tcctccttat
    28741 catactaact tccttttaag ctgactaatt tattttttta tagtaatggt ttgtgcttca
    28801 tgacctgtct ttatactata agtctcagga cttgtccata aaacattccc aatactatct
    28861 tttttaacaa gtttgactgc tatttcttta ttgattggta gatgagtatc aaagaaccag
    28921 tttgggtact tggcaatggt ctgagtgtta ttaaatagag gaccaacagc attcttagcg
    28981 tcatttgccc ccatctcaaa aacatcaccc atgagatata gttgttcccc tggtactgtc
    29041 ttaaaatcat tgatgagtaa acgaacagga atttgtttat cagtcaatac ttcaaaggct
    29101 tggtaactat tgctggtttg cttatcggca gttgtcactg aaatgttata ataatttgct
    29161 ggaaccgtcg gtacttttaa ggtgataagg gtatctgacc aagaaaggat ctcagcagag
    29221 atttctccaa aagtcacttg acctttagaa ttaccaaaac cttgacctga aatagtaatc
    29281 ttatttccag caatacccac tgaagcatcg acatctccaa gttgtggtgt cttgtcctct
    29341 ccttcataag tccatacagc gacttgcccc gctccaagtt caaagctact aatagtgcca
    29401 tctgctccaa ctattaattc ttgaccgcca agaagacctt ctaatttgtc cttgtagcta
    29461 ttttggggca aggctgtttt agcattagta attgtataac cattcgtttg atctctatta
    29521 atagccacta gtgcgacatg attaccaaat ttacgctcaa ataccaaaac atgatcacta
    29581 atccaacgtt gttcagttgt tccataagct aaagcttgat tttgttttct taaaggagct
    29641 agcttactaa tcactttata ggcttgtgac tctttattaa aacttggcat atcaccacga
    29701 ttattaggat ctttatcacc tgttgcatac tgctctgtac cataataaat attaggcaca
    29761 cctctagatg ttaaaagcaa agcataggct tgattaacag cagtttgatt attagccact
    29821 tttgttgcga agcgttccat atcatgatta tcaataaagg tcacctggtc tgtcacttca
    29881 ttagtcacct gatctctatt ttcaagaacc ttgtaaaaat ctcgcatggt aaacgttgaa
    29941 aaacctgtat acaactgtct aatagcattg gcaaatctaa aatctaaaag ccccatccca
    30001 ctattgttag caaatgtcgt catatcataa tcatcgtcgg tatgtcccga gaaccattcc
    30061 ccgaaaacaa agacattatg tttttcatag atatgactca accaattttt ttgccaacct
    30121 tgtgacatat gtttaacagc gtcaactcgg ataccatcaa cacccaggtc taaccattta
    30181 tcaatagctt ctttcatgta ctggtcaact ttcggattaa tgttatttaa atcagctagt
    30241 ccgtacattg aatgataaat agaattttca taagtactaa aatcggtcca agattcatga
    30301 ttaaaaatct tgtctttatc atctgaaaat ttaccaacta atttaccgtt tttatataaa
    30361 gcgccatctt ctttgaaagt tgtgccttct ttttcggctg tagacgtatg attaggagca
    30421 aaatcaataa ctaccttaat atggtgttga tgagctactt tgactagttg ttgaaagtct
    30481 gcttcagtgc caaaatgctg gtttgtttta aagaagtcct tagcccaata cccatgatat
    30541 gcagcacttc cattagaagg atcaatactg tcgatatttt caacaggaga agaaatccaa
    30601 atggcagaaa tccccatatc tgtcaggtaa ccatccttaa tcttggcgat gattccttgc
    30661 caatcacctc catggtattt tttaaggtca tttttatcaa aaacatcagt cttaccatta
    30721 ttagaggtat taccatcgtt aaaacgatct gttacaatct gataaatcgt atctgttgaa
    30781 aaatctgctt tgttggtgac agaagcatta tcggcagcag aaacagttag tggaaatgaa
    30841 attaagccaa gtaaaacagc acttttcgtt aataacttat aagttttgat atgtaattct
    30901 ctcatcgctt tttccttttc aaataacctt ttagttacta aacacaatat atccatcctg
    30961 gagtaattgt tttttgtttt tagttacccc attgcttgtc aaaatctgtc ctccttcctt
    31021 aatagaataa gcactctcac cattgttaag aacaagtgaa atgctttgct cacctaagct
    31081 gcgtttcaga atgaggcagt cttcgtcata atcaatgcta atagctcctt cttgaagagc
    31141 tggctgttgg cgaagagcaa taatcgcttt tactttgcta aagaaatcct tgtcccgctc
    31201 agcatcatcc caaggaaaac cgcgacgcga atcagggtcg taaccccctt ccattgccac
    31261 ttctgtccca taatacaagc aaggaatgcc cataaagata aagagcaatg ctaaagcagc
    31321 taacaattta tctttggaac ccttaacttg agtgaagaaa cgatgcgtat catgagaatc
    31381 caaaagattc aagttcatgc gattgacttg ccaagtgttt cgcatcaaaa tgttgcttaa
    31441 tttctcagcc aattgttttg atgtcatggt ttcaaaagca aagtaatcca aacaggcttt
    31501 ggtgaaagca taattcatta tcccatcata ctgatcccct gccaaataag gataggcatc
    31561 atgccagttc tccccaatta aaatggcatc tgctttttcc gctttaaccg cctgacggaa
    31621 acgtcgccaa aaatcatgag atacttcatc agaaacatct aggcgccaac catcgataca
    31681 aaattcttta atccagtatc gcccaatctc aatcagatag tcttgcacgt ctctatttga
    31741 ggtattccat ttgggcatat agttacatcc agcaaaggtt tcatagttta ctaggtccat
    31801 ggatgggtgt tcatcatgag tcataaacca atcaaaaaac ttagactctt taccgtatct
    31861 caagacatcc tgaaattcca cggcatcact gctggcatgg ttaaagacag cgtctagaat
    31921 aatcttgatt cccatttggt gagctaaatc aatcaattct tgcaaatcat atttagttcc
    31981 aaattgtgga tcaatagcgt agtaatcact aatatcatat ttgtgattac taatggattg
    32041 aaaaattggc gttaaataga tgacagtaat ccctaaatct ttgaggtaat ctaatttttc
    32101 tgtaattccc tttaaatctc caccagcaaa acttttagga gtcggttttt ctaaccaacc
    32161 catgttgaca taactgtcac ctttttccca atccccacgg ttaaagcgat caacaaagat
    32221 ttgataaaaa accgcgtctt ttgtccaagg aatgacttga tgaacatcaa cagcattgat
    32281 ataaggcatt tggaagaaat tataaaaccc atttgaaaaa tcgtaactag tagttaaccc
    32341 atcttcacta aaataatagg tttgaccttc ttcttcaatt ttaaaaatgt aggccaacct
    32401 cacatcgtct aatgttaaag tagtttcata ataagcatgc gtatggtctg tataggcaac
    32461 tgacatttcc aattcttctt ggaattcatg ataaccatat ttaggcccgt ggaccaaatt
    32521 aacagtaata cctctatctt ctttggccac gcgtaatcgg atgacaagtt ccttttgaga
    32581 tatggcaaag caatacctcg aatcaggaat atggagcatt ccggcaacat tcatttctac
    32641 ctccattaat aaagtattga cgattacttc tttttcttta aaacgaaaaa atagcagagc
    32701 gactcatact tctatatttt tagtatctgt ttcatcttca tcaaactaac agaaatagaa
    32761 gctgggcgta cttctttatc ccagcctccc ttctttgcct tattcagcgt atttttgttc
    32821 aatagcttcc ttaatagttt ttgctgcttc ttttgcagct ttagatgctt cttccttacc
    32881 agaagccacg ttaaagaaca tatttgcacc tggttcccaa acttcagcca tttctggaat
    32941 atttggcatt ggttgtgcgc tctcaaactg actaatcaca gctttcgtta actcattacc
    33001 ctctttagaa gcatagttac gtgctgttaa gttagctgga atttcttgtg ttttatcata
    33061 gaaacgtttt tggttttcag cattggtcac ataatcaagg aatttttgag cagtcgtttt
    33121 tcctttagaa tagtttgaaa taacccaagc tttaccacct gcgaacggtt ggtatttttt
    33181 accatttgtc aaagtaggaa tttccattac cccaaagtta acaccagcat ctttaaagga
    33241 gctagctgcc catggaccat caataatgac accagctttt ttagaaataa attgttcagt
    33301 gataaaatca ccagcttttt tagtgtcttg cattccttga ggccaagtgc cataccactg
    33361 tttcgcgtag tttaaccctt caacagttcc gtcgttacct aggcctaaat cacttggttt
    33421 ggttccttta tcaccaaaga tataactgcc ataaccggca attaaaccat aaccataata
    33481 gaagtctgtc catttcgcca agaaacctac agattttcct ggttcagagg caaaagcaaa
    33541 cttagaatct ttttgtaaga cttctaattc agtaaagctt ttaggtgctt gaggcactaa
    33601 atccttatta taataagtta ccaaagtttc aattacgtct ggtgcaccat aagttttacc
    33661 atcaatggtt actaatttct taaccgtatc atcaaactct ttgctgtttc ctaaagtaac
    33721 ctcagcgatt tgaccttcag ttcctaagcc acctacacgg tcaaaaggtg ctaaaaagac
    33781 atctggtgaa gctcctgttg gaccatccgt tgatagctta tcaagagtat ccatcatacc
    33841 ttcttttttg actttaacgg tgactttatg ctctttttca aactcaccct taatactctt
    33901 aatgtaatca acatatccct catcaacaga gactacaata gtctttccgt ctgtttcctt
    33961 aacgccttta ccaccaccac ttacgcaagc agttaggggt agcactgaag ctaaggataa
    34021 agttccaagc acagatgctt ttttccaatt ccatgacata acatgttcct cccgaaatgg
    34081 ttttttctta aacacaaatc aaatcatcta tctactctca tcatattagc aaataaaaga
    34141 taacataagg catttaaaat taataacagt aatagtttcg aaacttaaac gtttaagtta
    34201 agtttatcgt aatcgctttc atttgtcaat aactttttta cttttctttt aagagcatat
    34261 cagtagtttt tctgctaatt gaaaacaagg catttactgt cacacaagtc tgtcctttct
    34321 ttttttctac aactttattt cgtcagcgta aataaaacaa aagctctata atctcttgaa
    34381 tgggtaaatc cactgtagag attatagagc tttttgaata tcaaaaaagt cccataagat
    34441 ttataatgaa aagcaaccaa actctcatta gaaagactct tatggaacat atcaatcata
    34501 ccttacaaca catcggaatt aaagacaaaa atatcactct aaacaatgtt ttgaaggatg
    34561 aatctcctac tgagctcgtt actacttatc agaaaggtag ataggaaatc ctgatgaaga
    34621 gtgtgtccaa gggattatca attaggtctt agattacaaa atagtaattc aggtatgctc
    34681 tactgttttc aacactagtt ctgcaatttg ttttcgagct tgcttagctt ctcttattgg
    34741 aaaaataaca tacgcatgaa tcattttttc tgcaataatc agctgattag caattcgttg
    34801 tcttgttaat tgatcatgta aagacataat gtctgggtaa aaaatctctt ttgtcccaac
    34861 aaaggtcgtt atttcaggca aatcctcata atcaccatac aaaggactga cataaggaag
    34921 ttgcatatta ccttgaccac ctgcccatag ttcacctata tcacgaagac gacgagcatc
    34981 taggtaagct tcttctgctt caaaatcctt gtaggcttga tttttaaaac taacatctaa
    35041 ccaaggagat ataagaatta attgctttgg ctggggtgct gttttagtat ctcgtatata
    35101 cttagcaaac gccaaagcca tacccccacc agaagaatca ccaatgacac taacttgact
    35161 cggtccatta gacaagcaaa attgctggta agcttcaact aatttaggat agacatcttg
    35221 ataagtagca tacggtactt taggaaagtt aggaaaaaca accttggcat tagtcagctg
    35281 tataagatgc ttaaccgtct taaaatgaag tttttcgggt cgtcgtaaat agacactgcc
    35341 ataaagataa taaataacag gctgatgact ttgcttttga tcattaataa taaaaacttg
    35401 catcccgttc acatcgtatt cttgagttga aaaacctact atctcttcag gattatctag
    35461 atgataaggg atattacgat tacgctgcgt ctcaaccccc ttataattat caactttttt
    35521 agataactta tactttctat aagcaaacat tttctcaacc aaccaacttg aaaaggagcg
    35581 cttttgacca tattcaacta tcaaaatacc tagtatcact ccaaaaaaaa tcatcacagc
    35641 aataatgacc acttattatc ctcgttttct aatattattt tactattgca agtctttcct
    35701 atttgcccaa attttactat aaaaataagg gttcatttta tagttgggca ctggctgctt
    35761 cgtttctaga aatggttgca ctttcttatc aaaagctaac cagccattcc aaccgagatg
    35821 gatggtatct tgcataaagt aggactcacc accatctttt gagaagtcag caatgcgatg
    35881 aaatccttgt gactttaact ggaattttat tttacgaact gccgcttgat acttatcttg
    35941 atttaagccg gtataatccg cccaagcttt attaacagga gttataacaa agagtacatc
    36001 tgtttttcgt ttagcaaatt ctgataataa aagctgaaaa tcattgtatt ctggtgacgc
    36061 caggtaacta taattaactt ggaaattctt ataaagattg tatttaggtg ctattcgttt
    36121 acgataaaat gtatttttaa tcccaaaacg gttgttggtt gttgctaatt ggcctctctt
    36181 agttgctaat gcattcaatt gtttatacga aaatacttta ggtaatccct taacgcgagg
    36241 caaaattctt ttttcatagt tagtagattt gcctaaaaaa ctaaaaaggg actcttctct
    36301 caatgctact tgatgttgac atttcaaaat agctctgtct aaccgactaa gagacttacc
    36361 cttacttact tttttcaata agtttgattt agacacacca gggttaagct caagcaaacg
    36421 ctttgctgca aactgtgatt ctttatcagt tctagctttt agtaaaaatt caatcacttg
    36481 agtgttagac aagtacatct gaaccgcact aggattaatc ccttgagcag taaaccattg
    36541 aggagatact acaaagatgg cttttttctt ttgcatttca ttggtaattt gttgcatacc
    36601 ataataatgc gacaaagatg ctgatcctct cttaccaatt aaaaatggtc tatagctccg
    36661 cttgtagcgc tctgcaagca ccgaagggtg catactatcc attcgactcc attcgctaga
    36721 accaaaaaaa ggcacaaaac gacaaatctc atctgataaa gcttgtcttt taatcaaacc
    36781 atttttaaaa gaactatctg tgatcgcaac ggcatttgct ttttcctgag ctatggaatg
    36841 atcaagttgt gtaggaaaac taaaaatagt aatcactact aaaacaaagg caataagaag
    36901 aggacctaga attaaccaga gtctcttaag catgttgcaa ttcctctaca ccttgaacaa
    36961 tcttagttac tgtgttccaa tcatcacgac caaattctga aataggtact ttaatattga
    37021 acgttgactc taactcaaca atcaattcga ctgtcccaag actatccaac acacctgcat
    37081 caaacaagtc ttcgtccatc atctctgaaa catcttccat aaacaaacgg tcaaacaatt
    37141 caattacagt ttcttcaata gacattttta tacttccttt tattaatgta gtggtctgtt
    37201 aaaccaaagg tcatttaaaa aaccagagaa taacagaagt gaaaacatga caacgtggaa
    37261 agttaccacg atacataaga catggaatgc cctgctttga aagaggggtg ataggccttt
    37321 tttcttacgg tgacggttga tttctttttt cttacgaatc caagcatcat taataataag
    37381 tcctatacca tggaaaagcc cataagcgat ataataccag gttaagccat gccaaaatcc
    37441 catgactagc atattaacca gataggcaac acctgaagtg acatttcggt ttttaaaggt
    37501 tttatgctta atcaatagat gaaccaatcg cataaacaca taatctctaa accagaagga
    37561 caaactcatg tgccatctat tccaaaaatc tttcaaactt gcagataaga aaggcatgtt
    37621 aaagttttct ggtgttcgaa tacccaatag gtaggaaata ccaatcgcaa acatcgaata
    37681 accagcaaag tcaaaaaaga gattcaagcc atacacgtac ataaccagaa tagtttcctt
    37741 attaaagtag ccaccaacca tcaaagcctt attttcaagg agaggaagta agatgccacc
    37801 caaacaatag gaaatgatat gcttgtatag gaaacctaac atgagataca tgactgcctt
    37861 attgagcatt gcaaaataat catcacgttc aggaagttta tgataatctt cctgaaaacg
    37921 tctgaagcga tcaatggggc cacttgagaa agtggggaag aaaatcatga agcgaataaa
    37981 atccggtaaa cgaacctctt ggagagtccc gtcacgcatc tcaataatca ttccaatact
    38041 tttaaaggtc aaatatgaaa tccctagaaa actaaaaagt gtttgagaag aaggacctgt
    38101 taggggagca actttgaccc agataagggg gaataaggcc atcgcaatag ctaagtaaaa
    38161 cactcctgca ctattagctt tctcacggta tttctggtaa gcaaaaacac tgatgatttg
    38221 ccacaaaaga taaaagagaa aagcaactaa ttgttgataa tgatctcctc caaacataaa
    38281 gagaataaat accaaactca ccaaggtttc ataagtgctt aagcgctttt gtttaaaaat
    38341 cccaatgatg actggtaaga aagccaaaat aagatagaca aagtaaatgg ggttaccgta
    38401 aggttccatg tagggaatgt ggctaaaaaa catcatcatc ggttattgac ctcattaatc
    38461 aaagttttaa tatctatctt accatttgga gttaatggta gactatctcg ataaagaaac
    38521 ttagaaggca tcatataact catcatatga tccttaacag aggctttgat agctttggtt
    38581 aactccaatt ccctatcaaa acgctctcta accccatctt tgacaacgat ataggccaag
    38641 agattttgaa ccttatgttc tttattgtac cttggaacag ccacagccga tgctaccatt
    38701 ggtgattgat tcaactgttg ggaaacatct tctagttcaa tacgataacc agcatattta
    38761 atctgaaaat ccaaacgccc accatacagc aaaatattat cttctgtcaa tgagccaatg
    38821 tcccctgtat gataagcagg ctgtccttta aaagtaaaga aagcttctgc ggttttctca
    38881 ggattgttga ggtaaccttt tgacacagca ggccctgtaa caataatttc accctgctcc
    38941 cctgaagata actccttacc atcttcatca ataatatagg tcggagaatc tggtttgggg
    39001 tagccaatcg gcaagcgggt ataattatcc accatttctc tagtaatttc aatagcggat
    39061 aaggctacag tcgcttctgt tggtccatag gcattgataa tcttggcact cgggaaacgt
    39121 tcaaagagtt ttcgagccgt agaaacggtt aattcttcgc catcaaaata aaaatgcgtt
    39181 aaagctggca tcttagcctg gcaaaaatca tcgctaagca tggccatatc agcaaatgaa
    39241 ggagtcgatg tccaaatgcc aactggaagt tgcgcaatcg ttgtaaataa ctgtttaaag
    39301 tctgccacca attcttttgg aagtgcaaat aaggttccac ctaaagccaa ggtaggtgcc
    39361 cagtacatga cagaaaggtc aaaggaatag ggtggctgcg ccagcatttg tggttgttta
    39421 ggtacatcaa atgctgcatc ttcgatcatc cagttggtaa agctcaaaag attgtcatgt
    39481 gaaatttgca ccccttttgg ttggcccgtt gttccagagg tgaaaataat gtaataatta
    39541 tcatctcctt taacagaatg tgttcgctca tagggcattt ctgctaattt tgctgactca
    39601 atctctgata gtgagacaag ggaaatccct tcaatagtaa gagggaattc ctcaatagca
    39661 atgattaaac tgggctttgc aatctcaata atcgctaaaa tacgttctgg tgctgaatgc
    39721 acatctactg ggatataggc atgaccagat ttggttaaag ctacaaaagt agctaacata
    39781 tcataagttt gcgccccaaa aaccaaaact ggagattttg ccagtaaagc taagctatct
    39841 ataaatgcag caatgctatc agaatctctt ttgagttgtc cgtaagtgcg gcgttcccct
    39901 aaacaatcat aaactgggaa atcagcctgt gtctgagcaa actgctcaat actgtcaatc
    39961 atatccttaa tcatcagtca atctcctaaa attcattata aataaagtta ctttgaccat
    40021 gtcctagata accaaagaaa tagaccagca acattaaaat cagataaaat aaaattgtct
    40081 tgccaataaa aacagcaatt cctctcattc ttgatttgtt ttttatcata ctttaccttc
    40141 ttgtattagt gaaataatgt cctaaaaaat tctactcgaa aaaacctaac ttgacaagct
    40201 aaaagtcata ttattaaaaa gaaaattttt ttaaagctta actatttaga cagttaaatt
    40261 ttatgccttt ttactaaact tactaagtta atctttactt taaaaagtta acttaaaatt
    40321 gtcctaataa aaagaattat ttgactttaa cttatatatg ttaataagta taatataagc
    40381 tttattcaaa acctagtcca ttaatttaag ttctaaaatc aagtctcgca tttgagctgc
    40441 caattcgaaa tcaagtaatt cagctgcctc ttgcatttgt ttttgcagag cattgatcgc
    40501 ttctcttcgt tctcctcttg acatactttc ataatccatc tcttctttcg atatatcatt
    40561 gtggcttgtt ttacttatac taataaggcc tctgatgtct ttttttatag tttgtggaac
    40621 gatgccgtgc gctttgttat atgctacttg aatctcacga cgacgagccg tttcgtcaat
    40681 agcccgctgc atagaatctg tcatcttgtc cgcatacata atgacatgac catctacgtt
    40741 tcgagctgct ctaccgatgg tctgaatcaa gccgcgttca ttacggagga aaccctcttt
    40801 atcagcatcc aaaatggcta caagactaac ttctggcaca tcaatccctt cacggagcag
    40861 attgattcca atcaagacat caaaaacacc aagtcgtaaa tcacgaataa tttctgtccg
    40921 ctctaaggtt ttaatatcac tgtgcatata cttgaccttg acacccatct cttttagata
    40981 atcagtcaaa tcttctgcca tttttttagt taaggttgtg atgaacgtcc gttcatcgcg
    41041 cgctacgcgc tggttaattt ctcccaacaa atcatccatt tgccccatac ttggccttac
    41101 atcaatttca ggatcaagta gcccagtcgg acgaataatt tgctcaataa ttgtattagt
    41161 ctgtgacatt tcgtattcac caggcgttgc tgaaacatag acaatttggt gcacatgact
    41221 ttcaaattcc tcgcgtctta agggacgatt atcaagagct gatggcaatc gaaaaccata
    41281 gtcaactagc atttgttttc tggcttggtc accattatac atgcctttga tttgtcccat
    41341 tgtcatgtga ctttcatcaa tcataattaa aaaatcttct gggaagaaat ctaacaaggt
    41401 ataaggaggt tctcctggtg acctgccatc catatgacgg gaatagtttt cgactccgct
    41461 agtatagccc atttcacgta acatttcaat atcatattcc gttctttggc gtaatcgctg
    41521 tgcttctagt agtttacctt cagattcaaa taactgtaac tgctctgcta actctgcttg
    41581 aattttggct attgattgct ccatatgctc atcatttgtt acaaagtgag tagctggaaa
    41641 taaaaccaaa tggtcaactt ctccaatagt tttcccagtt aaactttcga tttcacatat
    41701 acggtcaatc tcatccccga aaaattccac ccgaaaagca tgttcatccc tggatgctgg
    41761 aaagacctca acaacatcgc cacgtacacg aaaacagccg cgttgaaaat caatatcatt
    41821 acgctcaaat tgaatatcta ctaattgatt tagcaaagtg tcacgtgata tctcctgacc
    41881 tggacgtagg ctgactgctg aatctgcgta ctcttttggc gaacctagtc cataaataca
    41941 agatacagaa gctaccacta tgacatcgtt acgctcaagt aaagaagagg tggctgaatg
    42001 gcgaagttta tcgatttcat cattgactga actatctttt tcgatatagg tgtcgcttga
    42061 tgggacatat gcttcaggtt ggtagtaatc ataataagaa acaaaatatt ccacagcatt
    42121 gtctggaaaa aattctttaa attcaccata taattgtcct gctaaggttt tattgtgagc
    42181 tatcactaag gtaggtttat ttactttact aattacttgg ctcatggtgt atgtttttcc
    42241 cgttcctgta gcacctagga gaatctgagc tttttctccg ccctcgatat tatcaactag
    42301 gctttcaata gcttgtggct gatcaccaga cggtttatac tttgatttta gtttaaatgg
    42361 tttatcatca cgtttatcaa tcattttata ccctctaata gtcttactct cttatagact
    42421 attttaacat agataagcca gaatcacctc caataagcgt aaaaaacatg tcatttatat
    42481 gttatgtttt atgacatata aataacaaat ttcttgctta atgttcaata ttttgttata
    42541 attaaccata ttttttagtt ttataaggag attagtatga cgcacaaaat aaaagtattg
    42601 ctgcttgcga taatgtctat ttttttgaca tgcaatattg caagtgctga aactattgct
    42661 attgtttcag atacagctta tgccccattt gaatttaaag actcagatca aatttacaaa
    42721 ggaattgacg ttgatattat taatgaagta gccaaacgtc aatcttggga tttcagtatg
    42781 agtttcccgg gttttgatgc agctgtaaat gctgttcaat ctggtcaagc gagtgctcta
    42841 atggccggta caaccattac gaatgctcgt aagaaagtct ttcatttctc agagccatat
    42901 tacgatacca aaattgtcat tgcgacacgt aaagccaatg ccatcaaaaa atacagtgac
    42961 ttaaaaggaa aaacggtcgg tgttaaaaat ggaacagcgg ctcaagcctt tttgaataac
    43021 tataaaaaaa agtatgatta tactgttaaa acatttgaca caggtgatct tatgtataat
    43081 agtttatctg ctggttctat tgccgctgtt atggatgatg aggcggttat ccaatacgca
    43141 atcagccaaa accaagatat tgctattaac atgaaaggag agcccattgg aagctttggg
    43201 tttgctgtca aaaagggaag cggatatgat tatctagtta atgatttcaa tacagctctt
    43261 aaagctatga aagctgatgg tacctaccaa gctatcatga ccaagtggtt aggcacagat
    43321 gataaagcta ccaccagtca ggcaacggga aatccatctg ccaaagctac acctataaag
    43381 gacagttata aaattgtctc tgattcgtct tttgcacctt ttgaatttca aaatggtaag
    43441 ggcaaatacg ttggtattga catagaatta atcaaagcta ttgctaaaca acaaggtttc
    43501 aaaattgaaa tcgctaatcc aggtttcgat gctgccttaa atgctgtgca atctagccaa
    43561 gcagatgggg tcattgctgg tgcaactatt actgacgctc gtaaagctat ctttgatttt
    43621 tctgatcctt attatacttc taatatcatt ttagctgtta aagctggaaa aaacatcaag
    43681 aactatgaag acttagacag aaaaacagtc ggtgctaaaa acggcacttc atcttactct
    43741 tggttaaaag aaaacgctcc taaatatggt tataatgtca aggcatttga tgatggttct
    43801 agtatgtatg atagcttaaa ttcaggttct gtagatgcta tcatggatga tgaggcggtt
    43861 cttaaatacg ctatctctca aggtcgtcgc tttgaaacac ctcttgaggg catttctact
    43921 ggtgaagttg gttttgctgt caagaaagga actaatccag aattaatcga aatgttcaac
    43981 aatggcttag ctgctctcaa aaaatctggt cagtatgatg acattataga taaatacctt
    44041 gactctaaga aagctgcaac tccttctgaa aaaggtgctg atgagtctac tatttcaggc
    44101 ctattatcaa ataactacaa acaactattg gcaggacttg gaaccacgct cagtttaacc
    44161 cttatttcat ttgctattgc tataattatc gggatcatct ttgggatgat ggccgtgtca
    44221 ccaactaaat cacttcgact catttcaacg gtctttgtgg acgttgttcg agggattcct
    44281 ttgatgattg tggctgcctt cattttctgg ggagtaccaa accttatcga gagtatgacc
    44341 ggccaccagt caccgattaa tgatttctta gctgctacaa ttgcactgtc acttaatggc
    44401 ggagcctata ttgctgaaat tgttcgcggt ggtatcgaag ctgttccagc agggcaaatg
    44461 gaagctagtc gaagtctagg tttgtcttac ggaaccacga tgagaaaagt aattctccca
    44521 caagctgtaa aactaatgtt acctaacttt atcaatcagt ttgttatttc attgaaggat
    44581 acaacaatcg tctcagcaat tggtttagtg gaactcttcc aaacaggtaa aatcattatt
    44641 gctagaaatt accagtcgtt ccgtatgtat gctattttag caattattta ccttatcatg
    44701 attacactct taacaagact tgcaaaacgt ttagaaaaga ggcttaacta atgacagaat
    44761 taaaaattga tgttcaagat ttacacaaat cttatggtca aaatgaagtc ttaaaaggaa
    44821 ttgatgccaa attctacgaa ggtgatgtcg tttgtatcat tggtccttct ggttctggga
    44881 aatcaacctt tctacgtacc ctcaaccttc tagagacgat taccagtggt aaggtcgtgg
    44941 tggacggttt tgaattatca gatcctaaga ctaatattga caaggcacgt gaaaatatcg
    45001 ggatggtatt ccaacacttc aaccttttcc ctcacatgac tgttcttgag aatattatct
    45061 ttgctcctgt tgaattaggt aaagagtcta aagaagttgc taaaaagcat ggcatggcac
    45121 ttctagaaaa agtcggactt tctgataagg ccgacgcctt cccaggaagt ttatccggcg
    45181 ggcaaaaaca gcgtgtcgcc atcgccagaa gtttagcaat gaacccagat attatgctct
    45241 ttgatgaacc aacttctgct cttgaccccg aaatggttgg ggacgttttg aacgttatga
    45301 aagacttggc agaacaaggc atgaccatgt tgattgttac tcacgaaatg gggtttgctc
    45361 gtcaagtagc taaccgcgtt atctttacag atggtggtca atttttggaa gatggaactc
    45421 ctgaagaaat ttttgaccat cctaagcacc ctcgtctcat tgaattttta gacaaggtct
    45481 taaacgtcta atagagcaga caccatacta acttccaaaa aataataagg caaggaaaca
    45541 ggtttccttg ccttttttgg ttactgttat tattcaaacc agcaaaatag ggatactctt
    45601 atgactctct ccttcataag agtgtcccct atgctttttt atgggcgttt atgtttagtg
    45661 aggtaataac ctaatcccgt aagagctagt cccgtcacta tgtgtaagta tttgttacca
    45721 accatcggac taatggcaat gagaaaaaag ccaacagcca ttaaaaaagt tgctccattt
    45781 ttttctgtca tgcaaggtca ctcgcttttt ctttattggc caaaatgaca aatggtgctc
    45841 agataaggaa ggcaacaaag aggttaaaca gtgaaaccaa acctgccata atattacctc
    45901 cagtagctag gtaagcataa agtccaacag gggtaatcca aggtactgat aagaataccg
    45961 gtggaatcaa acctattgca gtagcaaaat aagctatgct agcacaaatt ggtggcacaa
    46021 ttagccatgg aatcacaaag gttggattca aaacaattgg catcccaaat gtaattggtt
    46081 cgttgatatt gaaaacaccc attggtgcgg acaatttggc aatggtttta tgctcttctc
    46141 gttttgagaa tatgaagata gcaataatca atgccaaggt tactcctgag ccacccattt
    46201 gagcataagc atcaaaggac ccgcgtgtcc aaaggtatgg taaattagca gcgctatgcg
    46261 ctgtattgta agcagctgta ttttctgtta aagctaccat ataaatacca tccatcactg
    46321 gggctaagac attatgacca tgcaagccga agaaccagag cagttgaact aagaaggtta
    46381 acaagataac tgaaccaata ccctgtgata agcctagcaa tggtaattgg atataggttg
    46441 aaatgacatc acttagggaa gaacctgtta atgcaaagat gaggtaggcg aaaattgccg
    46501 aagcgtaaat cgcaactgtt cctggaataa tggcagcaaa ggctttatta accgcaggtg
    46561 gtacattatc tggtaaggta atggcaatat tacgtttggt caaagccgca tacacaaaac
    46621 ttgataaaaa gccaataatt aaagctgtga acaagcctgt ggcaccgaca tactttagag
    46681 ctattgctcc ccattgacta gtttcaatac ttgaagctcc acccgcagta acgactgaaa
    46741 gccccatttc tttcaaattg ctaattaggt tagcagaggc attttcaagt ggtgtcgaaa
    46801 tggttaaagt ctgaggtagg gtggcaataa atgagccaaa agaaatcaat cctcctgcca
    46861 atggattaat cttatgcata acagctaaat tgtaaccgaa agcaaaggca aaaaagagcg
    46921 ccatgatacc aattgtccca aaataaacat agccattgat gtcgataaca ggttgcatag
    46981 cttttgcaaa ccctgtccat cccatattgt ttggaatatc gcgtaaaaaa acgttcaata
    47041 agacagcaac tgaacctgcc atggtaatag acatcattga aataaaggaa tcacgaatag
    47101 ctactaaatg ccgttgtgac ccaatttttc ctgaaatctc cataaactta tcagaaaaat
    47161 gcgacataaa tcttctcctc tttttatttt tttaatgtaa caaaggtaac cttaaaagca
    47221 gcggtgtctg cctaacacaa ttatctcaaa atcatccttg ttaaacgtga tgcttagaga
    47281 caaccggtaa tcgactctta tccaaatgaa cccttctctc tcatccaagg tctgtgaata
    47341 atcttcacaa agacgatggt tgctgcaact gtttagcata ttggataagg gctgctaact
    47401 gagcttgaga ttggcgttct aggctttttt tgaacagttt gccaacaata aaatgatttg
    47461 ctttttgaaa aatatctaga ggatgatagt cataagaata ggtaattcta gtccgattct
    47521 cccccagagc ctctaatcga taagccaatt cctttatccc atgattggaa ctaaaacaag
    47581 cagtatataa ttgcggagct tctagggccg taataagcac cctcactgta cgctctttgt
    47641 atttaccata atgtttaaca tagtttatcc ccgctttgat atcatctctt gacaactgtc
    47701 tcaaggtatt ttgtcgataa tcttcttgga gcgatatcag catggcttca aaacaatgat
    47761 gaatggaaac atctccttct gctgaaataa tcatgactcg cccctctgta ttgctgacat
    47821 tttgtcgtaa acggtaacca attccttggc taaatcaata aaggctaagg cagtcatcat
    47881 gtgatcttgc ccatgcacca tcaataaaga caattcaacc gcatcaccag ctgcttcttg
    47941 ggacagcaaa tgtgtctgcg atttatgggc aatatttaac gagtttgtcg cttcttgaag
    48001 taagtgctga gcctcctcaa actgcccatc tcgtgctgca tgaatagcct ctacggcctt
    48061 gcccttggct tcgcctccat acatgattaa gcccataata gcttctaagt tggatggttc
    48121 cgtcatgcct actcctccat catcgctagg gctgtttcaa ggactttttc accgttcata
    48181 agaccataat cagccatgtt aatggcatct actttaatat ctggttcaaa cttatcttta
    48241 aaatccttta gtaagaattt gacttgtgga cctaacaaga gaacgtcaat gctattagca
    48301 gccacttcgt tgtcagcttc actcacagga actgcccaaa tagaaacttc aaggtcacgc
    48361 gcttgggctg ctttttgcat cttagtcacc aacatactag ttgacatacc ggcattacaa
    48421 actaacataa tagatttcat aaggtttctc cttttaatcg ttttaatcat gaataagtgg
    48481 ggtaaacact gtcatgaatt tggaataatt tggttcttct agtaacgctt gctgaagctc
    48541 cacctgattg acaaaagatg ccaaacctgg tgatacatat tttaacctat gattatgccc
    48601 tttagacggg gataatagaa agacaaaatg aacagcttga tgcgccttgt cccactcaag
    48661 aggctctcgg caaatagcca ctactacctg ttcagaataa gtcatgggat tagcaggatg
    48721 cggaaaggca agcacttctc catagatgac tgggctgtaa ttttccctca gtaccatttg
    48781 atgataaaag tcctctacaa acgtttctgt tcccgcctcg tcaagacaag caatcatccg
    48841 taaaagcaag tcttcctttg agattttctc gtctaaataa agaaaaagat tagggctaaa
    48901 aacacctgtt agaagctgct ctgcttttgc taaactcatc tgtgacggta aactgacctc
    48961 tttcttgata ccttcttgtt ctccaataaa ttgtcgaata gtttcaatat cctgatttga
    49021 caaaaaaaca ctgacagtaa tcactggtgt taaaaacatc agattggcaa ggctgataga
    49081 ggaaataatc aaatcaacgg ttttcagtcg ctcttcggtt atttcatagt aactgataac
    49141 atcgacaata cgcaaacgtc cttcaaattc cttttccaag cgatttttca acatcatggc
    49201 actaccataa cctgtggcac aaactactag aaccctcaat ttatgacggt ttgaataacg
    49261 ctcaatggcc gccattaaat gcaaactaat ataagcccat tcatcatctg agacatcatt
    49321 cttttgacat acaagcaaat ccgaaaaggt ctgcttggta agggtaaata tttcaggata
    49381 ctggctttta atttcctcag ttaaaggatt agtcagctga atatggtttt caagacgtgt
    49441 ggtcaagggc atcatgtggg ttaataaacc ttgaaataaa ttggtatctg tttctaaagt
    49501 catgcctgtc aattgactaa tcttggcaat acatgctttt aaatggtcct gcaacttttc
    49561 atcggtatta tcatcttgcc aatgcttacc aacagaatgt ttgaccttta gatgcagtgc
    49621 aatataatta gcctcctctt taggaaaacg tatccccatc acttcttcca ctcgatacaa
    49681 aatacgcaga gctacttgat actcatcaga ctgacgaata gctattggaa tggaaaacag
    49741 ttctaatgga caccccgatc gaatacgctg aaccattagg gcaatatgca agactagatt
    49801 attcatgaca aaatcagaaa gtttcaactt agcatcccga cattcatcca agacaataat
    49861 catgatttct gcaaaattaa taccttcaag aaaggtatta cctaccatgg tggacaaggt
    49921 attatcaaaa ctagtaacaa aaaaatagtc catgataaaa tgcctaatgt cctcttcttt
    49981 acctcttatt tgaatatgtt ggtgagttat ttcaagctct aactggtaag gtattatgcg
    50041 ctccttaatg cctgctaaaa catgttttaa agttgtccga ctgatataca attcttgaca
    50101 aagctcttca aaatcctgaa cggcatcttc aaaaaagaat ttatgaagca cataatcttc
    50161 tcgatcaacc gattcttcca cttgagtcac atctgccaaa cgttttttag acgtcacact
    50221 ttcttgccaa aagatgtcaa atgccataga atggtcaatt tctaagcagt aacctcgacc
    50281 ttgtttagaa atgatgtgag ctccgtgttc aggaaggcta ctgatcagtt ctttgaggta
    50341 tttcctaacc gtacggtcac tcataccaat aacctcagcc agagttgcac tagagacaaa
    50401 ctgctctttg tgatggatta gaaatgttat gatggccagt tctttttttg ataacattag
    50461 tcctccttac tactttagaa aacgctttct accctctttt agtgtaccaa atatttcctg
    50521 aaaaaggtga ccatcatttt ccgcattgat tgtgaaaaga atctatgatg gggcaatctc
    50581 caaacaaaat tcctgccaag gtcgtaaatc atctaacaaa ctaagatagt cctctctgac
    50641 ctcagcaacc acattagctt ttgaactgac cgtaaaattt ttcaaagcaa tttgcagttc
    50701 tcccttatat cgatgatagc ggtcattgtc aataataatg ctacctcgtt tgacctcctt
    50761 agattggtct cttggagcaa tcgattcctg agcatagact agacgtggca tggttgatcg
    50821 aatcacataa tcagatacat cgccacgata acaatgcgga tagccaatga tttgctcctc
    50881 aacttctgtc aaatcgatga taggcctaac cttgatcgtc gtgactggtc ttgctaaagc
    50941 ctgagtacat gctgccaatt cttcttccga aatgaattgg ttagatatga ggatattatc
    51001 aatggttcct atcgctttca ttaattctac ttgcaggcca atgggcaagt gcctatggtc
    51061 ttccactgtc ggcaagcctt ctgccagtag ccaagggctt tcagatgctg actgagcgct
    51121 aataaaagca gccgtttcaa tatcatgctc atgataaaaa cgtgacatat ccttaaaatg
    51181 ttgccatgac aaaccagtaa attcatgtgg ataaaaatta tggcaaccaa taatattgct
    51241 ccgttctgca tctgtcgcta gcaatgacat caataattgt ttatcagtgc tcatattaag
    51301 ttcaatttta agcccaaagg gatttcttgt taaagttaca atctctgcta gagggagagc
    51361 ctcgtctaag cgtaagcccg ctaacccgaa ggcatgagct cgttcaataa gctgatctga
    51421 ccaaccagct tggctaataa agcttggact aacgtcagca atcactcgaa tgcctaattg
    51481 atttgcataa gcaatgagct ctgcgtagca atgaaacatc tggtgatcag ctggtgccag
    51541 ctgtaagaga ctcataaaca agcgcttggc tccatggcta tgacataagt caatataagc
    51601 tttactcttg gtaacatcat accgcccagg gtatagagaa aatcctaaat caaccatatt
    51661 gcctcctatt tatcaaaacc atttgactcg ctcaacgcct taaaccagta acctgatttt
    51721 tttatggttc gcttttgact ctctaaatcc aaagctacca aaccatatcg gtttttataa
    51781 gcatttaacc aagaccagca atcaataaaa gtccataaga ggtagccttt gcagttggct
    51841 ccttctccca aagccttatg aagctggata agatgatcct cgataaaggt gatgcggtag
    51901 tcatcttgta tctggccatc tgctaaaaaa gcttcttcac cttcgacacc cataccattt
    51961 tccgtgacta gccattcgat gttaccatag tgttctttta aattaagagc aatatcataa
    52021 agtcctggtt tataaatttc ccaaccccgg tgaggattga cttttttacc aggcatatca
    52081 taaggttcaa aataaatatc taagataagg gggtccccct cttgctgtga cttactaggt
    52141 gcctgaaccc gcaaaggctg ataataatta actcccaaaa aatcaacagt attgtttttg
    52201 ataatctcta attcatcagc actatattga ggtaataaat cagcttcctc taaaatggaa
    52261 actaactctg ctgggtaaac acccaaaact gatggatcta gaaaggattt ggtttggaaa
    52321 agctctgcga ttctagcagc cttgacatct tcaggagcat cactccgagg ataagcaggt
    52381 gacatgttaa gcacaatact aatcttgtgg tcgggatgaa gcttatgaca agctttgacc
    52441 gccagtgaac tggccagttg tgtgttgtaa gccacttgaa ctgctgcctt ggcatctact
    52501 ttacaagggt agtgataata acctaaatag ccacattcga ctggaacaat cggttcatta
    52561 aaggtaatcc aagtgtttac taaatcacca aaaagctcaa aacaggtttt tgcgtaggtt
    52621 tcataagccc agacagtagc tttgttttcc cagccacctt tttcttgcaa ggcatagggg
    52681 aggtcaaaat gatagaggtt aacaatcaat ttaatacctt gagcaataat gtcttgaaat
    52741 acttctcggt aaaatgtcac cgcctttgga ttaacctccc cgactccttc tggaatcaat
    52801 cgagaccact ggattgaggt ccgaaaaatc gtgtggcctg tttctttcaa aagggcaatg
    52861 tcacccttat agttttcata aaaggttgag gttttttctg gaccaatttg gtgatgaaac
    52921 ttagctgact caatactaaa ccagtaaccc cagttgctag gtcctttgcc atctccagga
    52981 accgttcctt cgctttgagg cccagatgtg gaacttcccc ataaaaagcc atctggaaat
    53041 tgataacggt gttttctttg tttcatatcc tttatccttt ctttgctcac ttctcttttt
    53101 attataaaaa gaaaaacagg tgatgtaaac gctttaaaaa atctgttttt tccttatcat
    53161 cacggaaaat aagtgattta aagcttgaca tattttatta tcttaaagag cctatctaac
    53221 ctgccctgct acttcttatc aaaaccaagc ccctattgac agatgcctta gcctatgttt
    53281 gaataggggt atggcttatt taaactactt tacaaaaacc gagtgggcac tttggttaag
    53341 ctctgtcttg gccattttaa ttagcgccct tttattcggt aagcaagctc ccttagcttt
    53401 aatagcttct ttgattggtg tgacctctct catttttagt gctaaagcta atcctattgg
    53461 tcaagggctc gtcattattt tctccattat ctatgcctat ctttcattac gaaacagtta
    53521 ctatggagag ttaatgacct atcttttcat gaccctccct atgactattt tttcactttt
    53581 tacttggtta aaccatcctt ttgaagggaa aaaatcacaa gtgactattt cacgattaac
    53641 acccactgat cgaagatgtc ttttcgtttt tactatactg atcactctta ttttctacgg
    53701 catcttggct tctattcaaa cagcctattt acttgtctcc actttatcga ttgccacttc
    53761 tttctcagcg gtttatctca gctataagcg cagcccttat tttgctttgg cttatggact
    53821 caatgatcta gtcctcattc tcttatggat gcatgctgct caaacagatg ccagccaata
    53881 tgctgtggtc atctgctttg ccacctttct tattaatgat agttacactt tttataattg
    53941 gctaatgctc caacgttacc aagaaaaaaa ggtcaaaaaa ggatgagggc ctaagcctca
    54001 tcctttttca atttttcacg ttctaagcgc aaacgtctat tgggatttaa aagattaaac
    54061 aattcttcta atttctcagc attccaaaca tctgctgctg aaacaaagtt accatcctta
    54121 tccttaaagg atatcggttt atcacccata atcagaaacc tccatcttaa agataacaca
    54181 caagagcact atcacactgc tattgtaatg gattgcctta atccacaaat tcaaattcaa
    54241 acttgccaat acgaacagga tccccatctt ttgctccacg ctcacgtaga gcttcgtcaa
    54301 cccccatacc acgcaattga cgggcaaatt tcatgatgga ttcgtcacgt tccatattgg
    54361 tcatgacaaa gagacgttcc aatttctcac cagacaagac ccaagtagcg tcatcgtcac
    54421 gtgtgatctc aaagtctttc tcagcctcag caaaaccata gtaagcttcc tcgtccacca
    54481 gatcagattc atcatacaat aagaattcat ctgttttagc aagtaattct gctgttgctt
    54541 ctaacaagtt atctaagcct tgatgtgcta ggcttgaaat agggaaaatc attggtaggt
    54601 catcaaactc gtcatattgg gcagccaatt tttccttgaa ggctttcaag ttttcttgag
    54661 cctctggcat gtccatttta ttagccacaa taatctgtgg gcgctccatc aatcgcaaat
    54721 tataggtttc cagctcgtta ttaatggaaa cataatcttc gtaaggatca cgaccctcac
    54781 tagcagacat gtcaatcaca tgaagaataa cccgtgtccg ctcgatatga cggaggaatt
    54841 gagttcctaa accaacccct tggctagcac cttcaatcaa acctggcaga tctgccatag
    54901 caaagctatc acctgacttt gtacgaacca ttccaagatt aggaacaata gtggtaaaat
    54961 gataggcacc aattttcggt ttagctgatg acacaacact taacaaggtt gatttcccaa
    55021 cagatgggaa tccgaccaag ccaacgtcag ctaagatttt gagttctaac tctaactgac
    55081 gttcctcacc tggctcacca ttttcagcaa tctctggcgc aggattacga ggagttgcaa
    55141 aacgaatatt cccacggcca ccacgaccac ccttagcaat gaccacttct tgaccatgtt
    55201 ctactaagtc tgtaattact tttccagttt cagcatcacg aaccgttgtc ccttgaggaa
    55261 caaagacaat caaatcttct gcaccacggc cgtgcatgcc tttggtcata cctttttcac
    55321 cagatttcgc cttgaattta cgattatacc ggaaatccat caaggtacgc aaaccttcgt
    55381 ccactcggaa gataactgag ccacctttac cgccgtctcc tccccaagga ccgccatttg
    55441 ggacgtactt ttcacgacga aaagctacca taccatcgcc accacggcct gcttggacac
    55501 tgatttttgc cgtatctaaa aacatactca tacttttttt attctctaac tttcttttac
    55561 tttaaaaaaa cgcctttcag cgtttcctta cattaatact gatagggcac tcgcaataag
    55621 cccgccaaca gttacaagaa ccattaggat aacaacaaac attgttactt tttcaaaggt
    55681 tgtttttttg cgaggtccat tttctccaaa tgccacgtta aatacctcat ctattgattt
    55741 ttcttcttat atcttaacat gaaagatcgt tttaggcaaa taccagatga atatttacgc
    55801 tatgtaggct attactgagt attgtatctt gtgaatttca tatgaatatg atacattagc
    55861 atttgcaaaa taatgttaca gataaaaacc tcctcgtctg gtgaactgca ccccaaaagt
    55921 tagacacaaa atctaacgat tggggtgcta ttttttataa aatttaatca agaaacgaaa
    55981 gttaagattt atgagttacg gcaaatggga gagtccatta aatccatatc aaaaaagttt
    56041 gatatggcag aatccgatct caaatatatg attcgcttga ttgataggta tggggtaacc
    56101 attgttcaaa aatgtaagaa tcattattat tctccagaac tgaagcaaga gataataaat
    56161 aaagtcctga ttgacggcca atctcagaaa caaacatcct tagattatgc tttaccaact
    56221 tctagtatgc tctcaaggtg gatagcgcaa tacaagaaaa acggttatac tattcttgaa
    56281 aaaccaagag ggagaccgag caagatgggg cgtaaacgta agaaaaattt ggaagagatg
    56341 acagaggttg aacgtcttca gaaggaatta gaatacccta gagcggagaa tgctgtgcta
    56401 aaaaagctga gagaataccg cttgagggac gaagtaaagc tcaaagagca acagaaatca
    56461 ttcaagcatt aaggaatcaa tttcccttag agatgctact tgagatcctt gatttatcac
    56521 gctccaccta ttactatcaa gtgaagcgac tagctcaagg agataaggat atagaactaa
    56581 agcatgtgat tcgagagatt tatgatgagc ataaaggtaa ttacggttat cgtcgtattc
    56641 atatggagtt gcgtaaccga ggatttgtgg tcaatcataa gaaagttca
//
LOCUS       DATTYN010000010        54258 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.10, whole genome shotgun sequence.
ACCESSION   DATTYN010000010 DATTYN010000000
VERSION     DATTYN010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 54258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54258
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.10"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..1223
                     /locus_tag="VB649_000765"
     CDS             <1..1223
                     /locus_tag="VB649_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEP1669730.1"
                     /translation="YSRTVYISEGDINLTNNNKKLRISKDVDKLIKQSGKTFITSNLN
                     ATKHSTREYSYPYIKGTNAYYSFSYIPQALGILVGNALDLPILLTYYFGRLCNLISYA
                     ILAFIAIKLSGSFKQVIAVVTLLPMNIYLAASFNQDGFAIGLVLVTIGLFINLLSSKD
                     KSNYNTKFFLYLVLCGLLVLSKFTYFLLVCLPLFIPNEKFGKNTKLVILKKLGGLLLI
                     FLFAAMWFRLYGQVKTPYVADFLKEVNVSQQVKNMLESPIVYSSIIIRHMVINLINMN
                     NIFQFGALSYGITNLFPLYVCFFFFVYISNASKITINIVEKMGIIFVISAIIGATVLA
                     MYLTWTPVGSSTVLGVQSRYLIGIIPLVLLLFSSQQQKFKQIEDILSDKLAIHVSLLF
                     ILAMLMSTIFRYYH"
     gene            1317..2540
                     /gene="pepT"
                     /locus_tag="VB649_000766"
     CDS             1317..2540
                     /gene="pepT"
                     /locus_tag="VB649_000766"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEP1669731.1"
                     /translation="MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPE
                     MEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQ
                     GGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTS
                     QPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALE
                     VTFLGRNVHPGTAKDQMINALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEE
                     ARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMT
                     AIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MERAVDVIIGLVCKA"
     gene            2581..3069
                     /locus_tag="VB649_000767"
     CDS             2581..3069
                     /locus_tag="VB649_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEP1669732.1"
                     /translation="MIKLFGKIRYHWQPELSWSIIYWSIAFAPIFVGLSLLYERTEIP
                     SRVFILFAIFAVLVGIGLHRYFIIENNGILRIVSFKLFGPRKLLISTITKIEVTKSTL
                     CLHVEDKSYLFYMRKWPKKYFLDALAVNPYFQGEVILSDNFIKLDYFEVYQHDKKALT
                     RG"
     gene            complement(3056..3253)
                     /locus_tag="VB649_000768"
     CDS             complement(3056..3253)
                     /locus_tag="VB649_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEP1669733.1"
                     /translation="MKVSIIPEKCIACGLCQTYSSLFDYHDNGIVTFSSSSETSQSIC
                     PSDKDAILAVKSCPTKALTLE"
     gene            3302..3778
                     /locus_tag="VB649_000769"
     CDS             3302..3778
                     /locus_tag="VB649_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEP1669734.1"
                     /translation="MAKEPWEEKIVDDTIGTRTRKSRNAFISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNRQAETNGFYGASTHKKTRKASNAKKTSSSSTTTDTTPSSEETL
                     ASSEGTGETLTVLAGEGAASIAARAGISVEQLQALNPEHMTQGYWYANPGDQVTIK"
     gene            3793..4473
                     /locus_tag="VB649_000770"
     CDS             3793..4473
                     /locus_tag="VB649_000770"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEP1669735.1"
                     /translation="MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALTHGYTGKEVALILEELEKNPISFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWV
                     SALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
                     NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEK
                     AEKIVDMS"
     misc_feature    4497..4620
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            4635..5165
                     /gene="infC"
                     /locus_tag="VB649_000771"
     CDS             4635..5165
                     /gene="infC"
                     /locus_tag="VB649_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEP1669736.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     SNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     gene            5207..5404
                     /gene="rpmI"
                     /locus_tag="VB649_000772"
     CDS             5207..5404
                     /gene="rpmI"
                     /locus_tag="VB649_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEP1669737.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGLVSSGDFKRIKAMVTGL"
     gene            5463..5822
                     /gene="rplT"
                     /locus_tag="VB649_000773"
     CDS             5463..5822
                     /gene="rplT"
                     /locus_tag="VB649_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEP1669738.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVAD
                     AAAFTALADAAKAKLGK"
     gene            complement(6113..8323)
                     /locus_tag="VB649_000774"
     CDS             complement(6113..8323)
                     /locus_tag="VB649_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEP1669739.1"
                     /translation="MTSLGKNDKEVATVKKFKTLITGFINTRLGFIITLLFCYWIKTL
                     WAYHTDFSLDLGNIYQVFLTIINPIPLAFLLLGVALYVKNTRAFYICSWVVYIILNIL
                     LISNSIYYREFSDFITVSAMLASSKVSAGLGDSALNLLRIWDIIYILDFIILISLSIT
                     KKIKNDQRPFNKRAAFAITALSSLLLSINLFLAEIDRPELLTRGFSNTYIVRALGLPA
                     FTLYSGNQTYQAQKERNGATAEELIDVKTYVKGHYAAPDPQYFGIGKGKNIIVLHLES
                     FQQFLIDYKLKEGDKEYEVTPFINSLYHSNATLAFPNFFHQVKAGKTSDAETMMENSL
                     FGLNSGSFMVNYGGENTQFATPSILAQKGGYTSAVFHGNVGTFWNRNNAYKQWGYNYF
                     FDSSYFSKQNSKNSFQYGLNDKYMFKDSIKYLEQMQQPFYTKFITVSNHYPYTSLKGE
                     SSEEGFPLAKTDDETINGYFATANYLDAALKSFFDYLKATGLYDNSIFVLYGDHYGIS
                     NSRNSSLAPLLGKDSETWSEYDNAMLQRVPYMIHIPGYTNGSIKETFGGEIDALPTLL
                     HILGIDTSQFVQLGQDLLSPQNSQIVAQRTSGTYMTPEYTNYSGRLYNTQTGLEITNP
                     DEMTITKTKEIRSVVAQQLAASDAIQTGDLLRFDTQNGLKAIDPNQFIYTKQLKQLKD
                     ISAKLGSESTSLYSKNGHKSTQKLFKAPSYLELNPVEADAATSELKEDNTKNRE"
     gene            8431..9594
                     /locus_tag="VB649_000775"
     CDS             8431..9594
                     /locus_tag="VB649_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEP1669740.1"
                     /translation="MNKLYIDSFVEKKLTAGVQLLDEKDFSNIKEKNQLVQLVTKSNR
                     PIGTAYISKQNKGIGWYLGPEKIDLSISYFVSLFSVAKAKRQDFAQSDETNAYRLFNQ
                     EGDGFGGVTIDLYKDFGVFSWYNAFVYDKKEMIMEAFQQVFPEVKGAYEKCRFKGPDT
                     ETAHLYGELAQETFSILENGIAYQVFLNEGLMTGIFLDQHDVRRALVDGLAMGKSLLN
                     LFSYTAAFSVAAAMGGAIETTSVDLAKRSRELSLAHFEHNQLNLASHHFVVMDVFEYF
                     KYAKRKKLIFDVIVIDPPSFARNKKQTFSVSRDYHKLITEALDILSPKGTIIASTNAA
                     NMTVSQFKKQIIKGFGSRRPESMTLQQLPSDFTINKADERSNYLKVFTIKVRE"
     gene            9591..10277
                     /locus_tag="VB649_000776"
     CDS             9591..10277
                     /locus_tag="VB649_000776"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEP1669741.1"
                     /translation="MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAV
                     APAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS
                     VFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRI
                     IEVLEMDISN"
     gene            10371..11537
                     /gene="aroC"
                     /locus_tag="VB649_000777"
     CDS             10371..11537
                     /gene="aroC"
                     /locus_tag="VB649_000777"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEP1669742.1"
                     /translation="MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYG
                     RGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRR
                     VKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHH
                     ILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEKEIKTYIDKIKKEGDTIGGII
                     ETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEI
                     TWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKAT
                     VERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF"
     gene            11598..11939
                     /locus_tag="VB649_000778"
     CDS             11598..11939
                     /locus_tag="VB649_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEP1669743.1"
                     /translation="MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASQLFDE
                     FVAMQEKIQGTMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIER
                     IVFAPLKDLVK"
     gene            12160..13512
                     /gene="gorA"
                     /locus_tag="VB649_000779"
     CDS             12160..13512
                     /gene="gorA"
                     /locus_tag="VB649_000779"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEP1669744.1"
                     /translation="MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVN
                     LGCVPKKVMWYGAQVADILGTYAKDYGFDFKEKAFDFKQLKANRQAYIDRIHVSYERG
                     FEQNGVNRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISSDGF
                     FALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVEEM
                     AVGGPCLHPHSEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFGLDKTG
                     VTLNDKGYIETDAYENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKTDEKL
                     DYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMK
                     LVTVGDTEKIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR
                     "
     gene            complement(13599..14867)
                     /locus_tag="VB649_000780"
     CDS             complement(13599..14867)
                     /locus_tag="VB649_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEP1669745.1"
                     /translation="MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHV
                     VGTNGKGSVTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVI
                     RPILTKMSLETNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHAL
                     AVVCPSISFDHQERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGS
                     RLYQLGKDFLLNPSEKTFSFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFP
                     KISPKTIQKGIEATTWPGRSEFIQPNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILF
                     AGLKRKPLADLLAQLDTFEVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDE
                     LFVVTGSLYFISEVRQYCLSNANIFKNIFP"
     gene            complement(14897..15337)
                     /locus_tag="VB649_000781"
     CDS             complement(14897..15337)
                     /locus_tag="VB649_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669746.1"
                     /translation="MSSRYSRQQKPRKSGGVPTEHIKTGFTAFQKSIALIGSILSIIV
                     ATITITRALQPVPDKTSNDTPKESSNTIVKIIEKESSQVNQNHTGTSETTDDNKTTLP
                     SSSTAPSHNETTPTAPETPSTTEGTQLPNATGAEDANTGLPTNP"
     gene            15572..16714
                     /locus_tag="VB649_000782"
     CDS             15572..16714
                     /locus_tag="VB649_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP1669747.1"
                     /translation="MIYFDNAATTIPYGEALKTYQEVATKIYGNPSSLHQLGTNASRI
                     LEASRKQIAGLLGVKSEEIFFTSGGTESANWAIKGIAFEKTAFGKHIIISAIEHPAVS
                     ESVKWLLTQGFEVSYAPVTTQGVVDVNALAELIRPDTILISIMAVNNEMGAIQPIRAI
                     SNLLANQPTITFHVDAVQAIGKIPLCDYMTNRVDLASFSGHKFHSVRGVGFLYKKAGK
                     RLNPLLSGGGQEQELRSTTENVAGIASMAKALRIVTEKQVSVLPKLTAMRDVIYKALS
                     AYPDVTVFSAQEGFAPNILTFGIRGVRGEVIVHAFEKYEIYISTTSACSSKAGKPAGS
                     LVAMGIPVKTAQTAVRISLDDDNDMGQVEQFLTIFKQIYDKTQKVR"
     gene            16716..17930
                     /gene="thiI"
                     /locus_tag="VB649_000783"
     CDS             16716..17930
                     /gene="thiI"
                     /locus_tag="VB649_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEP1669748.1"
                     /translation="MDYSEIMVRHGELSTKGKNRMRFINKLKNNIQDVLAPFPAITVR
                     SDRDRTYVSLNGTDYQPIVEALKLVFGVQALSPVYKLEKSVPLLVTAVQDIMTSLYRD
                     GLTFKIATKRSDHAFELDSRELNSLLGGAVFEVLPNIQAQMKHPDVTLKVEIRDEAAY
                     ISYEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGLDIEVVHFASPPYTSPG
                     ALAKAQDLTRRLTRFGGNIQFIEVPFTEIQEEIKNKAPEAYLMTLTRRFMMRITDAIR
                     EQRKGLVIVNGESLGQVASQTLESMQTINAVTSTPIIRPVVTMDKLEIIEMAQVIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLGNAEKYEERFDIDGLVQRAVSGIVVTEITPEIV
                     NDEVENLIDALL"
     gene            17968..19260
                     /locus_tag="VB649_000784"
     CDS             17968..19260
                     /locus_tag="VB649_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEP1669749.1"
                     /translation="MILLKSLYKGFFAAMKEENFEARCYNREKGGCVLIKTMQYKKTM
                     ATVVALIVALLLFGLIYDLLGVQKNELAAQKSAQPKVKTARVVANGDILIHDILYMSA
                     RKADDTYDFTPYFEYVKDWISGADLAIGDYEGTISPDYPLAGYPLFNAPEEIAGALKN
                     TGYDVVDLAHNHILDSQLDGALNTKKVFHQLGIDSIGIYDKDRSKESFLIKNVNGIKI
                     AILGYSYGYNGMEATLSQEDYEKHMSDLDEAKIKKELQLAEKKADVTIVMPQMGTEYA
                     LEPTAEQKELYHKMIDWGADVVLGGHPHVIEPSETVIKGRQKKFIIYSMGNFISNQRL
                     ETVDDIWTERGLLMDLTFEKKDNKTKIKTVEAHPTMVLAKGKGIVGKEGFELYNYRTM
                     VLEDFIKGGKYHDNIDEETKAKVALAYQEINDLVNLKW"
     misc_feature    19365..19439
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            19474..19788
                     /gene="rplU"
                     /locus_tag="VB649_000785"
     CDS             19474..19788
                     /gene="rplU"
                     /locus_tag="VB649_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEP1669750.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            19800..20126
                     /locus_tag="VB649_000786"
     CDS             19800..20126
                     /locus_tag="VB649_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEP1669751.1"
                     /translation="MIKAIFTRQKNGQLSSVTLTGHAGSGKHGFDIVCASVSTLAINF
                     VNSLEVLADCQALVDLNDVEGGYMAITIPPHDNKEEVQLLFESFLLGMTSLAKDSSKF
                     VNTQVI"
     gene            20154..20447
                     /gene="rpmA"
                     /locus_tag="VB649_000787"
     CDS             20154..20447
                     /gene="rpmA"
                     /locus_tag="VB649_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEP1669752.1"
                     /translation="MLKMNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK"
     gene            20795..21709
                     /locus_tag="VB649_000788"
     CDS             20795..21709
                     /locus_tag="VB649_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEP1669753.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSIKDLEAELG
                     FQIFNRTTSGTVLTSQGLVFYEKALEVVKSFDSFEKTFSQADLDQNEFSIASQHYDFL
                     PPLITAFSQQYDGHRVFRIFESTTIQILDEVAQGNSEIGIIYLNVDNQKGLFQRMDKL
                     GLEYVSLIPFTTHIYLSKTHPLANREALYLSDIQGLPAVRFTQERDEYLYYSENFVDT
                     SECPRIYNVSDRATLNGILERTNAFATGSGFLDHRSVNGIKVIPLADHIDNQMIYVKR
                     KDKNLSVAGATFVTILKDYFDKRRKALT"
     gene            21706..22164
                     /locus_tag="VB649_000789"
     CDS             21706..22164
                     /locus_tag="VB649_000789"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEP1669754.1"
                     /translation="MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLT
                     YLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGN
                     FIDRLRLAYVIDMVHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN"
     gene            22154..23044
                     /locus_tag="VB649_000790"
     CDS             22154..23044
                     /locus_tag="VB649_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP1669755.1"
                     /translation="MEINVITSGQRLDKALADLSPLSRGQANDQIKQGLVLVNGQQKK
                     AKYTVQAGDVICFELPKEEVLEYQAQNIPLDIIYEDDALAIINKPQGMVVHPSAGHPS
                     GTMVNALMYHIKDLSSINGVVRPGIVHRIDKDTSGLLMVAKTDAAHQALAEELKAKKS
                     LRKYLAIVHGNLPNDRGMIEAPIGRSEKDRKKQAVTAKGKEAVTRFTVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDPLYGPRKTLSGHGQFLHAKTLGLTHPMTGKEM
                     IFTVEAPEIFQKVLKLLRKK"
     gene            23440..23961
                     /gene="pyrR"
                     /locus_tag="VB649_000791"
     CDS             23440..23961
                     /gene="pyrR"
                     /locus_tag="VB649_000791"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEP1669756.1"
                     /translation="MKTKEIVDDVTMKRAITRITYEIIERNKQLDNVVLAGIKTRGVF
                     LARRIQERLHQLEGLDLPIGELDTKPFRDDMRVEEDTTLMSVDITGKDVILIDDVLYT
                     GRTIRAAIDNLVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSSVEEIVVEVVE
                     VDGRDRVSIIDPT"
     gene            23977..25236
                     /locus_tag="VB649_000792"
     CDS             23977..25236
                     /locus_tag="VB649_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEP1669757.1"
                     /translation="MKDVIYDVEEVPKAGMLVGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTKFKIPAYMGSSFAYIAAMQLLMKTNGIGAVAQGAMTGGLVY
                     LIVALIVKAIGNDWIDNILPPIVVGPIVMVIGLSLASTAVNDVMLKNGNYNLTYLVIG
                     LVTLLSVIFFNIYGKGIVAIVPILLGLLVGYVVALLVGVLTGQEIVDFTNVAQAKWFS
                     IPSVEIPFLTYGVKFYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGFAQIIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAALLSFIGKVSA
                     LIQSIPTPVIGGISVALFGVIASSGLKILIESKVDMDNKKNLLIASVILVSGIGGLML
                     QVNGLQISGVAFSTLLGIILYQVLPEK"
     gene            25297..26232
                     /locus_tag="VB649_000793"
     CDS             25297..26232
                     /locus_tag="VB649_000793"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEP1669758.1"
                     /translation="MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDH
                     QKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALG
                     TDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGRFEGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELD
                     VLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDFAIIMHPAPVNRDVEIADS
                     LVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS"
     gene            26276..27358
                     /gene="carA"
                     /locus_tag="VB649_000794"
     CDS             26276..27358
                     /gene="carA"
                     /locus_tag="VB649_000794"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEP1669759.1"
                     /translation="MTKRLLILEDGTIFEGEPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLIGNYGINRDDYESISPTCKGVVVSEVSRLASNWRKQMTLDAFLK
                     IKGIPGISGIDTRALTKIIRQHGTMKATMADDGDSIQHLKDQLRATVLPTNTIEQVST
                     KTAYPAPGIGKNIVLVDFGLKHSILREFSKRQCNITVVPFNITAEEVLQLNPDGLMLS
                     NGPGNPEDLPEALDMIRGVQGKIPIFGICMGHQLFSLANGAKTCKMTFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERSSLPDTLMVTHEDINDKTVEGVKHRDFPAFSVQFHPDA
                     APGPHDASYLFDEFLEMIDSWRCTSK"
     gene            27604..30780
                     /gene="carB"
                     /locus_tag="VB649_000795"
     CDS             27604..30780
                     /gene="carB"
                     /locus_tag="VB649_000795"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004218948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEP1669760.1"
                     /translation="MPKRKDIQKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYKV
                     ILVNSNPATIMTDKEIADKVYIEPLTLEFVNRIIRKERPDAILPTLGGQTGLNMAMAL
                     SKAGILDDLEIELLGTKLSAIDQAEDRDLFKQLMQELDQPIPESTIVKTVDEAVTFAR
                     DIGYPVIVRPAFTLGGTGGGICSSEEELCEITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLKIIRALK
                     IEGGCNVQLALDPYSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     INPITGTTYAMFEPTLDYVVAKIPRFPFDKFEHGERQLGTQMKATGEVMAIGRNLEES
                     LLKACRSLEIGVCHNEMTSLSNISDEELVTKVIKAQDDRLFYLSESIRRGYSIEELES
                     LTKIDLFFLDKLLHIVEIEQDLQMHVDHLESLKKAKRYGFSDQKIAEIWQKDESDIRA
                     MRHSHSLYPVYKMVDTCAAEFDAKTPYFYSTYELENESVQSNKESILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQKAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAQALSEAGVTILGTQVEDLDRAEDRDLFEKALKELGIPQP
                     QGQTATNEEEALEAAKKIGFPVLVRPSYVLGGRAMEIVENKEDLREYIRTAVKASPEH
                     PILVDSYIFGKECEVDAISDGKSVLIPGIMEHIERAGVHSGDSMAVYPPQQLSKQIQE
                     TIAEYTKRLAIGLNCIGMMNVQFVIKNEQVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKLILGQTLKDLGYEDGLYPQSQLVHIKAPVFSFTKLAQVDSLLGPEMKSTGEVMGSD
                     TSLEKALYKAFEANNSHLSEFGQIVFTIADDSKAEALSLARRFKAIGYQIMATQGTAA
                     YFAEQGLSACLVGKIGDAANDIPTLVRHGHVQAIVNTVGIKRTADKDGQMIRSSAIEQ
                     GVPLFTALDTAKAMLTVLESRCFNIEAI"
     gene            30986..32257
                     /locus_tag="VB649_000796"
     CDS             30986..32257
                     /locus_tag="VB649_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEP1669761.1"
                     /translation="MSKRGKIKITTKTKLITASVITLVLIITGVVLWKQQQNTLTADI
                     AKEPYSTVSVTEGSIASSTLLSGTVKALSEEYIYFDANKGNDATVTVKVGDQVTQGQQ
                     LVQYNTTTAQSAYDTAVRSLNKIGRQINHLKTYGVPAVSTETNKDEATGEETTTTVQP
                     SAQQNANYKQQLQDLNDAYADAQAEVNKAQIALNDTVVISSVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGQLQVKGTLTEYDLANIKVGQSVKIKSKVYSNQEWTGKISYVSNYPT
                     ESNAGSTTPAGSTGAGSSTGAAYDYKIDIISPLNQLKQGFTVSVEVVNEAKQALVPLT
                     AVIKKDKKHYVWTYDDATGKAKKVEVTLGNADAQQQEIHKGVAVGDIVIANPDKNIKP
                     DKKLEGVISIGTNTKPEKDSQSKNKKSGVDK"
     gene            32257..32967
                     /locus_tag="VB649_000797"
     CDS             32257..32967
                     /locus_tag="VB649_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669762.1"
                     /translation="MSHEKKQLMQLSNIVKSYQNGDQVLKVLKGINLTVYEGEFLAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYTLHNTKIEILNDRELAKVRNDEIGFVFQQFFLL
                     AKLTALQNVELPLIYAGVNVSKRREQAKQFLEKVGLGRRIKHLPSELSGGQKQRVAIA
                     RALVNDPSIILADEPTGALDTKTGQQIMELLTELNKEGKTIIMVTHEPEIADFATRKI
                     IIRDGDITTDTTASVVID"
     gene            32979..34199
                     /locus_tag="VB649_000798"
     CDS             32979..34199
                     /locus_tag="VB649_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669763.1"
                     /translation="MENWKFALSSIWGHKMRSILTMLGIIIGVAAVVIIMGLGNAMKN
                     SVTSTFSSKQKDIQLYFQEKGEEEDLYAGLHTHENNHEVKPEWLEQIVKDIDGIDSYY
                     FTNSATSTISYEKKKVDNASIIGVSKDYFNIKNYDIVAGRTLTDNDYSNFSRIILLDT
                     VLADDLFGKGNYKSALNKVVSLSDKDYLVIGVYKTDQTPVSFDGLSGGAVMANTQVAS
                     EFGTKEIGSIYIHVNDIQNSMNLGNQAADMLTNISHIKDGQYAVPDNSKIVEEINSQF
                     SIMTTVVGSIAAISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIES
                     VVLTVLGGLIGLLLAQLSVGALGNAMTLKGACISLDVALIAVLFSASIGVFFGMLPAN
                     KASKLDPIEALRYE"
     gene            34453..36186
                     /locus_tag="VB649_000799"
     CDS             34453..36186
                     /locus_tag="VB649_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HEP1669764.1"
                     /translation="MTFLSDLISLMTKIRLSWVIKAGIFQLLFVTIANIVLSEFFYFI
                     LDVTGQYHLDKDNVVTFLKNPIALALLGAYLFLLAAFIHLEFFALYRIIADQEISFYL
                     FRKQFSYYLRGLWKTFSGYQLLLFLLYILLTIPVLHIGLSSVITQKLYLPEFIVGELS
                     KITSTKYLLYGSLILVFYLNLRLVYFLPLIAINHRTVAQAWRESWQKTKKKHVLLWMK
                     LFAINGLTIVVLSLAISMILIFVDMFNPKGNNIIVQLGALTFTWELIFFTTIFFKLCS
                     AMILKEAIEPQKQYDEPRRSNKAYVVIFIVVTVGFAYQSLERLTFFDTSHSKTVIAHR
                     GLVSAGVENSLEALEGAKKAGSDYVELDLILTKDNHFVVSHDNRLKRLAGVNKTIRNL
                     TLKEVEHLTSHQGHFSGRFVSFDTFYQKAKKLNMPLLIELKPIGTEPGNYVDLFLETY
                     HRLGISKDNKVMSLDLEVIEAIKKKNPSITTGYIIPIQFGFFGDEFVDFYVIEDFSYR
                     SYLSSQAFWNNKEIYVWTINDPKRIEHYLLKPIQGIITDQPALTNQLIKDLKQDNSYF
                     SRLVRIISSLY"
     gene            36313..36585
                     /gene="rpsP"
                     /locus_tag="VB649_000800"
     CDS             36313..36585
                     /gene="rpsP"
                     /locus_tag="VB649_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEP1669765.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQITIKEDRVLEWLSKGAQPSDTVRNILSKAGVMAKFHDQKFSK"
     gene            36595..36834
                     /locus_tag="VB649_000801"
     CDS             36595..36834
                     /locus_tag="VB649_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEP1669766.1"
                     /translation="MDTIENLIIAIVKPLISQPDNLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            37766..40792
                     /locus_tag="VB649_000802"
     CDS             37766..40792
                     /locus_tag="VB649_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat protein"
                     /protein_id="HEP1669767.1"
                     /translation="MKKHLKTVALTLTTVSVVTHNQEVFSLVKEPILKQTQASSSISG
                     ADYAESSGKSKLKINETSDPVDDTVTDLFSDKRTTPEKIKDNLAKGPREQELKAVTEN
                     TESEKQITSGSQLEQSKESLSLNKRVPSTSNWEICDFITKGNTLVGLSKSGVEKLSQT
                     DHLVLPSQAADGTQLIQVASFAFTPDKKTAIAEYTSRAGENGEISQLDVDGKEIINEG
                     EVFNSYLLKKVTIPTGYKHIGQDAFVDNKNIAEVNLPESLETISDYAFAHLALKQIDL
                     PDNLKAIGELAFFDNQITGKLSLPRQLMRLAERAFKSNHIKTIEFRGNSLKVIGEASF
                     QDNDLSQLMLPDGLEKIESEAFTGNPGDDHYNNRVVLWTKSGKNPYGLATENTYVNPD
                     KSLWQESPEIDYTKWLEEDFTYQKNSVIGFSNKGLQKVKRNKNLEIPKQHNGVTITEI
                     GDNAFRNVDFQNKTLRKYDLEEVKLPSTIRKIGAFAFQSNNLKTFEASDDLEEIKEGA
                     FMNNRIETLELKDKLVTIGDAAFHINHIYAIVLPESVQEIGRSAFRQNGANNLIFMGS
                     KVKTIGEMAFLSNRLEHLDLSEQKQLTEIPVQAFSDNALKEVLLPASLKTIREEAFKK
                     NHLKQLEVASALSHIAFNALDDNDGDEQFDNKVVVKTHHNSYALADGEHFIVDPDKLS
                     STMVDLEKILKLIEGLDYSTLRQTTQTQFRDMTTAGKALLSKSNLRQGEKQKFLQEAQ
                     FFLGRVDLDKAIAKAEKALVTKKATKNGQLLERSINKAVLAYNNSAIKKANVKRLEKE
                     LDLLTGLVEGKGPLAQATMVQGVYLLKTPLPLPEYYIGLNVYFDKSGKLIYALDMSDT
                     IGEGQKDAYGNPILNVDEDNEGYHALAVATLADYEGLDIKTILNSKLSQLTSIRQVPT
                     AAYHRAGIFQAIQNAAAEAEQLLPKPGTHSEKSSSSESANSKDRGLQSHPKTNRGRHS
                     AILPRTGSKGSFVYGILGYTSVALLSLITAIKKKKY"
     gene            40812..41213
                     /locus_tag="VB649_000803"
     CDS             40812..41213
                     /locus_tag="VB649_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEP1669768.1"
                     /translation="MITQEMKDLINNQLAMVATVDAKGQPNIGPKRSMRLWDDKTFIY
                     NENTDGQTRINIEDNGKIEIAFVDRERLLGYRFVGTAEIQTEGAYYEAAKKWAQGRMG
                     VPKAVGIIHVERIFNLQSGANAGKEINSESN"
     gene            complement(41379..42254)
                     /locus_tag="VB649_000804"
     CDS             complement(41379..42254)
                     /locus_tag="VB649_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEP1669769.1"
                     /translation="MPASKKVTIIFILNLSFSLIEFIFGTLFFSGAILADAVHDFGDA
                     IAIGISAILERKAVKKESPNFSLGYKRFSLLGALTTNLILISGSLLVMIETIPKLWHP
                     TIVNYDGMFVLAIFAIIINGFASFIIHSNQTKNEEILSLHFLEDILGWLAIIILSLIL
                     KWKPWYILDPLLSIAIASFILSKALPKLVATANIFLDGVPDSIDYCTLHHELSQLPHI
                     VSVNQLNVWSMDGIDHRATIHCCLRESTTEKHCKKSIRLICQRYNINSITVEIDTSLN
                     EHQHHCSSLSNIEVN"
     gene            42390..42911
                     /locus_tag="VB649_000805"
     CDS             42390..42911
                     /locus_tag="VB649_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP1669770.1"
                     /translation="MTKDRQIKKTKTAIYSAFIALLQKKEYSKITVRDMITLANVGRS
                     TFYAHYESKEMLLKELCEELFHHLFRQKRNVTFEDYLVHLLKHFEQNKDSIATLLLSN
                     DPYFLLRFKNELEHDVYPNLRCKYIDKTTIPEVFLKQFVLSSFIETLKWWLHQRQRMS
                     ANELLKYYLELIK"
     gene            43126..43644
                     /gene="rimM"
                     /locus_tag="VB649_000806"
     CDS             43126..43644
                     /gene="rimM"
                     /locus_tag="VB649_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEP1669771.1"
                     /translation="MEYFNVGKIVNTQGLQGEMRVLSVSDFAEERFKKGSQLALFDDK
                     DRFVQEVTIVSHRKQKHFDIIKFKDMYHINAIEKYKGYTLKVSKDNQGDLQEGEFYYH
                     QIIGMAVYEKDVLIGHVKEILQPGANDVWVVKRQGKRDLLLPYIPPVVLNVDVPNKRV
                     DVELMEGLDDED"
     gene            43634..44365
                     /gene="trmD"
                     /locus_tag="VB649_000807"
     CDS             43634..44365
                     /gene="trmD"
                     /locus_tag="VB649_000807"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEP1669772.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEE
                     LIFICGHYEGYDERIKILVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLKKTYLRRPDLL
                     EHYNFAEEERKLLDKIKEALGQGED"
     gene            44365..45357
                     /locus_tag="VB649_000808"
     CDS             44365..45357
                     /locus_tag="VB649_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP1669773.1"
                     /translation="MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQP
                     AILYPEKMIYDIPAYPSLTGAELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSI
                     RTNKAEHFSKTIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICG
                     GGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKASTVNLLTPYVPKALKGIG
                     NLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTS
                     QEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID"
     gene            45535..46593
                     /locus_tag="VB649_000809"
     CDS             45535..46593
                     /locus_tag="VB649_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEP1669774.1"
                     /translation="MTTTDKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     MAAAEFLHIVQVFQFFTPIMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLRGIGDLINMMITASLAVLAVKYFGNKFGSLTIILLPITIGTGVGYIGWK
                     FLPYVSYVTTLIGQGINSFTTLQPILMSILIAVAFSLIIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTAAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKHPIMAIPMVFTAA
                     ISSLTVPLFNLVGTPASSGFGLVGAVGPIASLAGGSSILIIILAWIIVPFAVAFAAHK
                     VSKDILKLYKEDIFVFEG"
     gene            46606..47529
                     /locus_tag="VB649_000810"
     CDS             46606..47529
                     /locus_tag="VB649_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEP1669775.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGL
                     IVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDVKGIIGKETKVLCLLN
                     GLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPSNQEAGHQV
                     ADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEI
                     IHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGINTPYCRMITELVHAKEAVLNIQ"
     gene            47785..48498
                     /locus_tag="VB649_000811"
     CDS             47785..48498
                     /locus_tag="VB649_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP1669776.1"
                     /translation="MAKITEENYVSLEDLMQLLNSSESTIRRDLGELEQEGRLHRVHG
                     GAELFHSLQEELSNQEKSVKNSHIKKAIAQRASQFIYDNDVIFIDAGTTTEFLLPFLQ
                     AKNLTVVTNSIHHAASLVELSIETIIVGGYVKQTTDASIGNVALEQIRQMNFDKAFLG
                     MNGVDDSYLTTPDMEEAVIKKAVLSNAKLAYILVDGTKIGQVSFVKVAPINDVTIITL
                     GGSASILKQIKEKAKVIEL"
     gene            48495..49406
                     /gene="pfkB"
                     /locus_tag="VB649_000812"
     CDS             48495..49406
                     /gene="pfkB"
                     /locus_tag="VB649_000812"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEP1669777.1"
                     /translation="MIYTVTLNPSIDFIVRIDQINLGSVNRMASDDKFAGGKGINVSR
                     ILQRLDIASTATGFLGGFTGRFIEESLSAEGVKTDFVKGDQDTRINVKIKSQEETELN
                     GQGPIISQEQLEDLKTKLSQLTAEDTVVFAGSAPANLGNAVYKELLPLVRQSGAQVVC
                     DFEGQTLIDALAYNPLLVKPNNHELEAIFGTILTSLDDVETYARRLLEMGAQNVIISM
                     AGDGALLVTKEATYFAKPIKGEVKNSVGAGDSMVAGFTGEFMKSQNPIEALKWGVACG
                     TATAFSDDLATIAFIKETYHKVEVEKR"
     gene            49403..51349
                     /locus_tag="VB649_000813"
     CDS             49403..51349
                     /locus_tag="VB649_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP1669778.1"
                     /translation="MKIQDLLRKDIMILDLQAISKEVAIDEMITKLVEKDIVHDFDVF
                     KKSIMTREEQTSTGLGDGIAMPHSKNIVVDKPAVLFAKSNKGVDYKALDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADKLRAAATPEAVIAVFDEASTAKEEVVAPT
                     SGQDFIVAVTACPTGIAHTYMAEEALKKQAAEMGVAIKVETNGASGVANRLTAEDIQR
                     AKGVIVAADKAVEMDRFDGKQFIARPVADGIKKSQELISLILNNEGNTYHAKNGKSET
                     AVSTEKTSLGGAFYKHLMGGVSQMLPFVIGGGIMIALAFLLDNMLGVPNDQLGSLGSY
                     HEIAAIFMNIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASNGLAFGKVPFA
                     AGGEVSLGLTGVPSGFLGALVGGFLAGGVILALRKLLAGLPRSLEGVKSILLYPLLGV
                     LVTGFLMLFVNIPMAAINTALNDFLQGLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVANGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIVMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGIKLMAPHGGIFVIALTSNPI
                     LYLVFVVIGALVSGILFGALRKKA"
     gene            51442..52041
                     /locus_tag="VB649_000814"
     CDS             51442..52041
                     /locus_tag="VB649_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP1669779.1"
                     /translation="MKVKKRRRRARSSVNRLVLGLVLLNLIVSMWTLKLGNQRLAPYA
                     DHETLTFVRKISHAAQSVAQKKQLYSSVMMAQAILESNNGKSQLSQKPYYNFFGIKGS
                     YKERSVIFPTLEDDGQGNLYQIDAAFRSYGSLTACFLDYARVLNDPLYDKTHKKFWSH
                     YQDATATLTGTYATDTTYHTKLNELIEWYQLTNFDGLMK"
     gene            52193..52900
                     /locus_tag="VB649_000815"
     CDS             52193..52900
                     /locus_tag="VB649_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEP1669780.1"
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSS
                     TRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYHNFFGIKGAYNG
                     SSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
                     ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYT
                     DAETLAVDEAWAKRMTY"
     gene            complement(52957..53268)
                     /locus_tag="VB649_000816"
                     /pseudo
     CDS             complement(52957..53268)
                     /locus_tag="VB649_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(53472..54146)
                     /locus_tag="VB649_000817"
     CDS             complement(53472..54146)
                     /locus_tag="VB649_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
                     /protein_id="HEP1669781.1"
                     /translation="MFIYTFKTEKLVESKNSNIDEIKHQLRYIYTITPSDYSNCNISY
                     LTTHNFSVATSGYQSKCFYVDSEVDGGVTEKFRKGQKVNVFGLPYIFSPYNKNDIYGG
                     ITPSTDDGILRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEFDFKIRKFLMESKE
                     IYLTKSPYIRGSLEIHSKNRKHEKINLYDAKPNSTRSDVFKKYKDNKTINMKDFSHFD
                     IYLWTK"
BASE COUNT        17323 a         8922 c        11104 g        16909 t
ORIGIN      
        1 attattcaag gacagtttat atctcagaag gtgatattaa tcttaccaac aataacaaaa
       61 agttaagaat atccaaagat gttgataagc ttattaaaca gtcaggaaaa acatttataa
      121 catcaaactt gaatgcaact aaacacagca caagagagta tagctatcct tacatcaaag
      181 gaactaatgc atattatagt ttttcttata taccacaagc tttgggtatt ttagtaggaa
      241 atgcgctgga tttacctata cttttaacat attatttcgg aagattgtgc aaccttatta
      301 gctacgctat acttgctttt atagctatca agttgtctgg ttcttttaaa caagtgatag
      361 ctgttgttac tttactacct atgaacattt atttagcagc atcttttaat caagacggct
      421 ttgctatcgg tttagtttta gtaacaattg gattgtttat taacttgctc tcatcaaaag
      481 ataaatctaa ctataatacc aaattcttcc tttatttagt tctatgtggg ttactagttc
      541 tttcaaaatt cacatacttt ttattagtat gccttccatt atttattcct aatgaaaaat
      601 tcggaaaaaa taccaagtta gtcatcttga aaaaattggg aggactatta ctcatttttc
      661 tttttgctgc aatgtggttt agactttatg gacaggttaa aaccccatat gtcgcggatt
      721 ttctaaaaga agtaaacgtt agccagcaag ttaaaaatat gctagaatcc cctatagtct
      781 atagcagtat tattattaga catatggtaa ttaatctgat taatatgaat aacatttttc
      841 agtttggcgc attaagctat ggtataacga acctattccc gctttatgtg tgtttcttct
      901 tttttgttta tattagtaat gctagtaaaa taactattaa tattgtagaa aaaatgggta
      961 taatctttgt tatttcagcg attataggtg caactgtatt agctatgtac ctgacttgga
     1021 caccagtagg gtcctcaact gtcttaggtg ttcaaagtcg ttatctgata ggaattatcc
     1081 cattagtgtt gcttcttttt agtagtcaac agcaaaagtt caaacaaata gaggatatcc
     1141 tttctgacaa actggctatt catgtttcgc ttttgtttat tctcgcaatg ttaatgagta
     1201 ctatttttag atattatcat taaactctta attagaggct ttaaaaaact tagcttgaat
     1261 aagtatttta aagcctttta tgctataatt aaattgagaa attattgagg tggcctatga
     1321 agtacgataa cttgttagat cgatttataa aatatgtcaa agtgaataca agaagcgatc
     1381 cagacagtga gactactcct agtacggaga gtcaagaagc atttgcctta acgattttaa
     1441 agcctgaaat ggaggcaatt ggtttgcaag atgttcatta taatccagtt aatggctatc
     1501 ttattggaac tctgcctgcc aataatccaa ccttgacgcg taaaattggt tttatagccc
     1561 atatggatac ggctgatttc aatgctgaaa atgttaatcc gcagattatt gacaattatc
     1621 aaggagggga cattacactt ggcagttcta attataagtt ggatccaaaa gcatttccaa
     1681 atcttaataa ttatatcggt caaacattga ttaccactga tgggactaca cttttagggg
     1741 cagatgataa atctggtatt gctgaaatca tgacagcaat agaattctta acatcacaac
     1801 cacaaataga gcactgtgac attaaagtgg cttttggccc tgatgaagag attggggtcg
     1861 gagctgataa gtttgaggtg gctgattttg aggtggattt tgcttatact atggatggcg
     1921 gtcctttagg cgaattgcaa tatgaaactt tcagcgctgc agctctagaa gtgacttttt
     1981 taggcagaaa tgttcatcct ggtacggcta aggatcaaat gattaatgcc cttcagttag
     2041 caatagattt tcatgagaag ctacctgcta aagagcgacc tgaatacaca gatggttatc
     2101 aaggcttcta tcacttaacc ggactaactg gaacagttga agaggcacgc gcatcttaca
     2161 ttattcgtga ttttgaagaa gcatcatttg aagctagaaa agtgaaagtt gaaaatatag
     2221 ctcaatcgat gaatgctcag ctaggaacaa aacgtgtctt ggtagagctt aatgaccaat
     2281 actacaatat gaaaaaagtt atcgaaaaag atatgactgc tattgagtta gctaaagaag
     2341 taatggaaga gcttgctatc aagcctgtaa tcgaacccat acgtggagga acagatggct
     2401 ctaaaatttc atttatgggt attcccactc ctaatatttt tgcagggggt gagaatatgc
     2461 acgggcgttt tgagtttgtt agcttacaaa cgatggagag agctgtcgat gtcattattg
     2521 gacttgtttg caaagcctaa ttatcatgta attgatattt agtggaaggg gcttataaaa
     2581 atgattaaac tatttggtaa aataaggtat cactggcagc cagagttgtc ttggtctatt
     2641 atttattggt ctattgcgtt tgcacctatt tttgtaggtt tatctttgtt gtatgagcgc
     2701 actgaaatac ctagtcgggt ttttattcta tttgctattt ttgctgtcct agttggcatt
     2761 ggattacatc gttatttcat tattgaaaat aatggtattt taagaatcgt atcttttaaa
     2821 ttgtttggtc cgcgtaagct acttatttcc actattacta agattgaggt gaccaaatca
     2881 acactttgtc tgcacgttga agataaaagt tatctctttt atatgcgcaa atggcctaaa
     2941 aaatattttc ttgatgcctt agcggttaat ccatacttcc aaggagaagt tatattaagt
     3001 gataacttta ttaaattaga ctattttgaa gtttatcagc atgataaaaa agcccttact
     3061 cgagggtaag agctttagtt gggcaagatt tgacagctaa aatagcgtcc ttatctgaag
     3121 gacaaattga ctgacttgtt tcagatgagc ttgaaaatgt gacgatacca ttgtcatgat
     3181 aatcaaaaag tgatgaatag gtttggcata gaccacaagc gatgcatttt tctggaatga
     3241 tagatacttt cataactatt attctaatat gattttgtta aattaacaag gggggacgat
     3301 catggctaaa gaaccatggg aagaaaaaat tgttgatgat actataggga cacgaacacg
     3361 taaatcaaga aatgctttca ttagcacgcc ttggttgact gctttattaa gtgtattctt
     3421 tgtcatcatt gttgctatac tttttatttt cttctataca tcaaatagcg gtagtaatag
     3481 acaagctgaa acaaatggtt tttatggagc atccactcat aaaaaaacaa ggaaagcttc
     3541 taacgctaaa aaaacatcaa gtagttcaac aactacagac acaacacctt ctagcgaaga
     3601 aacacttgct tctagtgaag gaactggcga aacccttact gtattggcag gtgagggggc
     3661 agcttctatt gcagcccgtg caggtatttc tgtggagcag ttacaagcac ttaatccaga
     3721 gcacatgact caaggatatt ggtatgccaa tccaggagat caagtcacta ttaaataatt
     3781 gaagaggaaa aaatgaaagc aattaaaatt gcgattgatg ggccagcttc aagtggaaaa
     3841 agtacagtag ccaagattat tgcaaaaaat cttggctaca cttatctaga tactggtgct
     3901 atgtatcgct cagcaactta tatcgcactg acacatggct atacgggtaa agaagtagcc
     3961 cttattttag aggaacttga gaaaaatcct atttccttta aaaaagcaaa agatggctcc
     4021 caattagttt ttcttgggga tgaggacgtg accttagcca ttaggcaaaa tgatgtaact
     4081 aacaatgttt cttgggtctc agctttgcca gaaattagag aagagctggt tcatcaacaa
     4141 agacgcattg cacaagctgg tggcattatc atggatggtc gtgacattgg aacggttgtt
     4201 ctcccagatg cggaactaaa aatcttttta gtggcttctg tcgaagagcg ggcagagcgc
     4261 cgctataaag aaaacctaga aaaaggaatt gaatcagatt ttgagacgct aaaagaagag
     4321 attgcagctc gtgattacaa ggatagtcat cgtaaggttt cacctctaaa agcagctgaa
     4381 gatgccctta tttttgatac cacaggtgtt tctattgatg gcgtggtgca atttatccaa
     4441 gaaaaagcag aaaaaatagt tgacatgtcc tagagcctat gttagaatag taacaatgag
     4501 aaaagtagaa gtgagagctt ctcgccttgc gacttaggtt gtctggccct aacatgtcaa
     4561 attcctatgg aatattatgt gtgcgggctt gatttatcaa gtccgctttc gtttttctct
     4621 aaaaaaataa agaggtgaag atcatagcta aaaaggatct attcattaat gatgaaattc
     4681 gcgttcgcga agttcgtctc gttggtcttg aaggtgaaca attaggtatt aaaccattgt
     4741 ctgaagcgca atcattggct gatgcttcaa atgttgattt ggttttaatc cagccacaag
     4801 ctgttcctcc tgttgccaaa cttatggact atggaaagtt caaatttgag tatcaaaaga
     4861 aacagaaaga acaacgtaaa aaacaaagcg ttgtgactgt gaaagaagtt cgtctcagtc
     4921 cagttatcga taaaggtgac tttgaaacaa aacttcgtaa cggtcgtaaa ttccttgaaa
     4981 aaggaaataa agttaaggtt tctattcgtt tcaaaggacg tatgattact cataaagaga
     5041 ttggtgccaa ggtactagct gactttgctg aagcgactca agatattgct atcattgagc
     5101 aacgagcaaa aatggatgga cgccaaatgt ttatgcaact tgcaccaatt tcagacaaga
     5161 agtaattgtc acagtttcat tatatcttta agaggagaat actaaaatgc caaaacaaaa
     5221 aacacaccgc gcatcagcta aacgttttaa acgtacaggt tcaggcggtt tgaaacgctt
     5281 ccgcgccttt acatcacacc gtttccacgg aaaaactaaa aaacaacgtc gtcatcttcg
     5341 taaagctggt ttggttagct caggagattt caaacgtatc aaagcaatgg ttactggtct
     5401 ttaattttaa aggcagtaga catttacgag tattataaga attatttgaa ggagaactat
     5461 taatggcacg tgttaaaggt ggcgttgttt cacgcaaacg tcgtaaacgt attttaaaat
     5521 tagctaaagg ttactatgga gcaaaacaca tcttgttccg tactgcaaaa gagcaagtga
     5581 tgaactctta ctactatgca taccgtgatc gccgtcagaa aaaacgtgat ttccgtaaac
     5641 tatggatcac tcgtatcaat gcggctgctc gtatgaacgg tttgtcatac tcacaattga
     5701 tgcacggttt gaaacttgct gaaatcgaag taaaccgtaa aatgcttgct gatttagcag
     5761 tagctgatgc agcagctttc acagctcttg ctgatgcagc caaagcaaaa cttggcaaat
     5821 aagaaacgct atacctaaaa aataactttc tattacctat agaaagttat aaagaaacaa
     5881 aaatgaagga gacgatggac gtcttctttt tattatactc aatataataa aaaatagttt
     5941 cccatgtttt attaccagta atgtgggata tttagatggt agcaagaagt tttatagctg
     6001 atttgttttc tttaggtcta attagcatat tttgattact gataaacttg aatatcgcca
     6061 ataaaaaaga agcaaaatta ttattttgct tctagtcaga tcattaaatt gattattctc
     6121 tatttttggt gttatcctct tttagttcag aagttgccgc gtcagcttct acgggattta
     6181 gttctaagta agatggtgct ttaaaaagtt tctgagttga tttatgacca tttttactgt
     6241 ataaacttgt tgactctgat ccgagttttg ctgaaatatc tttcagttgt tttaactgct
     6301 tagtgtagat aaactggtta ggatcaatag cttttagacc attttgagta tcaaagcgca
     6361 ggagatcacc cgtttgaata gcgtcgctag ctgctagttg ttgagcaaca acagagcgaa
     6421 tttccttagt tttggttata gtcatttcat cgggattagt gatttctaaa cctgtttgcg
     6481 tgttgtacag acgtccacta tagttagtgt attcaggagt catataagtc ccagatgttc
     6541 gttgtgccac aatctggcta ttttgaggtg ataataaatc ttgtcctaat tgaacaaact
     6601 gactagtgtc aataccaagt atgtggagta aagtaggaag agcatcgatt tcaccgccaa
     6661 aggtttcttt gatactacca ttcgtataac ctggaatatg gatcatatac gggactcgtt
     6721 gtagcatagc attatcatat tcagaccaag tttcagaatc tttaccaaga agtggagcaa
     6781 gactagaatt acgagaattt gaaataccat aatggtcacc atataaaaca aaaatagaat
     6841 tgtcgtacaa accagtggct ttcaagtaat caaaaaaaga tttaagggca gcgtctaaat
     6901 aattggcagt agcaaagtaa ccattgatcg tttcatcgtc tgttttggct aaaggaaaac
     6961 cttcttcact actttcgcct tttagactag tataaggata gtgattactc acagtgataa
     7021 acttggtata aaaaggttgt tgcatctgtt caagatattt tatggaatcc ttaaacatgt
     7081 acttatcatt taacccatat tgaaaagagt tcttactatt ttgtttagag aagtagctag
     7141 aatcaaaaaa ataattatag ccccattgtt tataagcatt attgcgattc cagaaagttc
     7201 caacgttacc atgaaagaca gcgctggtat agccaccttt ttgggctaaa atacttggag
     7261 tagcaaattg tgtattttca ccaccgtagt tcaccataaa agaaccacta tttaaaccaa
     7321 ataaggaatt ctccatcatg gtttcagcat cagaagtttt acctgcttta acctgatgaa
     7381 aaaagttagg gaatgctaag gtagcatttg agtgataaag cgagttgata aaaggcgtta
     7441 cctcatattc tttatctcct tcttttagtt tataatctat taagaattgt tgaaagcttt
     7501 ctaaatgaag aacaataata tttttgcctt ttccaattcc aaaatactga ggatcaggtg
     7561 ctgcataatg tcctttgaca taagttttaa catcaattaa ttcttctgca gtagctccat
     7621 ttcgttcttt ttgagcttga taggtttgat tgccgctata gagggtaaac gctggtagtc
     7681 ctaaagctct cacaatataa gtatttgaaa agccacgtgt taatagttcc ggacgatcaa
     7741 tttctgctaa aaaaagatta atagaaagca atagactaga taaagcggtg atggcaaatg
     7801 ctgcgcgctt gttaaaagga cgttgatcat ttttgatttt tttagtgata gataaactaa
     7861 ttagaataat aaaatcaaga atatagataa tatcccagat gcgtaaaagg tttaaagcag
     7921 agtcccctaa tccagcggag actttactac tagctagcat ggcactcact gtaataaagt
     7981 ctgaaaattc tcggtaatat atagaatttg atatcaagag aatgttaagg ataatataaa
     8041 ccacccaaga acagatataa aaggctcggg tattcttaac gtaaagagca acccccaaaa
     8101 gtaaaaaagc tagtgggatt ggattgataa tagttagaaa gacttggtat atatttccca
     8161 aatctagtga aaagtctgta tgatatgccc acagggtctt tatccagtaa caaaagagta
     8221 gagtaattat aaaacccaat cttgtgttga taaaacctgt gataagtgtt ttaaatttct
     8281 tcacagtagc aacttcctta tcgttttttc ctaaagatgt catctccaaa taaaatctca
     8341 gattaaatta taccaaaaat gtgaagctaa tgcttgttgt aagttcaaat ttagtaggat
     8401 tttttatcag attttgttat aataaaaact atgaataaac tctatattga ttcttttgtc
     8461 gaaaagaagc tgacagcagg ggtacaatta ttagatgaaa aagatttttc taatataaag
     8521 gaaaaaaatc agttggttca actggtgacc aagtccaatc gtcccattgg aacagcatat
     8581 atctctaagc aaaataaagg aattggttgg tatctaggac cagaaaaaat cgacttgtct
     8641 atctcttatt ttgttagtct attttcagtt gctaaggcca aaagacaaga ttttgctcaa
     8701 tcggacgaga ccaatgctta tcgccttttt aatcaagaag gagacggttt tggtggagta
     8761 acaattgatc tttataaaga ttttggagtc ttttcatggt acaatgcctt tgtctatgac
     8821 aaaaaagaaa tgattatgga ggcttttcaa caggtttttc ctgaagtcaa aggagcttat
     8881 gaaaagtgtc gctttaaagg tccagatact gaaactgctc atctgtatgg tgagctggca
     8941 caagaaacct tttcgatttt agaaaacggc atagcctatc aagtcttctt gaatgaaggc
     9001 ttaatgacag gtatttttct agaccagcat gatgttagaa gagcactagt agatggttta
     9061 gctatgggca agtcccttct taacctattt tcctatacag ctgccttttc tgtagcagct
     9121 gctatgggtg gtgctatcga gaccacttct gtggacttgg ctaaacgatc gagagaatta
     9181 tcactagctc attttgagca taaccagtta aacttagcct cacatcattt tgtggtgatg
     9241 gatgtttttg aatacttcaa atatgccaaa cggaaaaaat taatctttga tgtgattgtg
     9301 attgacccac caagctttgc tagaaataaa aaacaaactt tctctgtgag cagggactac
     9361 cacaaattaa tcacagaggc cttggacata ttgagtccta agggaactat tatagcttca
     9421 acaaatgctg ctaatatgac tgttagccag ttcaaaaagc aaattatcaa aggatttgga
     9481 agtcgtcgtc ctgagtctat gactctccag cagcttccga gtgactttac tatcaataaa
     9541 gcagatgaaa gaagtaacta tttaaaggta tttactataa aggtacgaga atgagaattg
     9601 tagcaccagt catgccaaga cattttgacg aggctcaagc cattgatatt tctaaatatg
     9661 aagatgttaa tttaattgaa tggcgagcag actttcttcc caaggatgag attgtcgcag
     9721 tagcaccagc tatttttgaa aaatttgccg gaaaagaaat tatctttacc cttcggactg
     9781 ttcaagaagg ggggaatatt accctttcaa gtcaggagta tgttgatatt atcaaagaaa
     9841 tcaatgctat ttataatcca gactatattg actttgagta ttttacgcac aagtcagtat
     9901 ttcaagaaat gcttgatttt ccaaatctta ttttgtctta tcacaacttt gaagagactc
     9961 ctgaaaattt aatggaagct ttttcagaaa tgaccaagtt ggcaccgcgt gtggttaaaa
    10021 ttgctgtgat gccccagagt gaacaagatg ttctagattt gatgaactat accagaggct
    10081 ttaagacgct caatcctgag caagaatttg caactatatc tatggggaaa ttaggaagat
    10141 tgtctcgttt tgcgggagat gtcattggct cttcctggac atacgtttca ttagatcatg
    10201 ttagcggtcc aggtcaagtg actctcaatg atatgaaacg tattattgag gtcttagaaa
    10261 tggatatatc taactagtga atggtctaaa aatattattt ctacaatagt taagaaatga
    10321 tgtttttaga ttaatgtttt taaaataagt ggaaccaaaa aggagaaaaa ttgcgttatt
    10381 taacagcagg agaatctcat gggccatcct taacagctat tattgaaggt ataccagcag
    10441 gattaactct tcatccagcg gatattgatc acgaattaca gcgacgtcaa ggaggttatg
    10501 gccgtggtgc cagaatgtct attgagactg atcgggttca aatatcctca ggagttcgtc
    10561 atggcaaaac aacaggggcc cccattacct taacggtaat taataaggat caccaaaaat
    10621 ggctagatgt catggctgta ggagacattg aagagactct caagttaaag cgtcgtgtta
    10681 agcatcctag accaggacat gcggatttgg taggaggtat taaatatcat tttaacgatt
    10741 taagagatgc cttagagcgt tcctcggcta gagaaacaac gatgagagtg gctgtaggcg
    10801 ctgttgctaa acgtatctta gctgaacttg gaattgatat gttacatcat atcttaatat
    10861 ttggtggtat aacgatcaca ataccttcta agctctcttt tagagagctg caagaaaggg
    10921 ctctccattc agaattatct attgttaatc caaagcaaga aaaagaaatt aaaacgtata
    10981 ttgataagat aaaaaaagaa ggggatacca ttggtggtat tattgaaacg atagttcaag
    11041 gggtgccagc aggtcttgga tcttatgtcc aatgggataa aaaattagat gccaagctgg
    11101 ctcaagcagt tctttccatt aatgctttta aaggggtgga atttggagtt gggtttgata
    11161 tgggattcca aaagggctct caggtaatgg atgaaatcac ctggacacct acccaaggct
    11221 atggtcgtca aacaaaccac ttaggtggct ttgaaggtgg catgaccaca ggacaacctc
    11281 ttgttgttaa aggggttatg aagcccattc ctactttgta taaaccactc atgtcggtag
    11341 atattgatag tcatgaacct tataaagcaa cggtggaacg ctctgatccg acggccttac
    11401 cagctgcagg ggttatcatg gaaaatgtgg tggcgacggt gcttgccaaa gagattttag
    11461 agactttttc ttctactacc atgtctgaat tgcaaaaagc tttttcggac tatcgtgcct
    11521 acgtcaagca attttagata gcgagatact ggcttttatg gtatcataca ggtattaatg
    11581 aacaaaagga gactgtcatg tcacaagaaa tttatgacta tgctaatcaa cttgaaagag
    11641 cagttcgtgc tctgccagaa taccaaaaag tgttagaagt aaaagaggcc attcaagcag
    11701 acgctagtgc tagccaactg tttgatgagt ttgtcgctat gcaagaaaaa atccaaggga
    11761 cgatgcaatc aggccaaatg ccaacggctg aagaacaaac aagcattcaa gaacttagcc
    11821 aaaagattga agctaatgac cagctaaaag cttattttga agcgcagcag gccttatctg
    11881 tttacatgag tgatattgag cgtattgtat ttgctccgtt gaaagattta gtcaagtaag
    11941 ccaattaaga taggaaaaaa acagattgct ggcagctcgt caggatctgt tttttagtgt
    12001 ttattttctt tgtatcagaa agttgagcct ctttcttatt tgtgatatag tcaaataaag
    12061 tgaccaaaat agcaggccag tagtggcttt aatgaaggca agttgtctgc taactggcta
    12121 tgctaaaaca tcagtattag aaagtaaaag gtgataaaaa tggttattcc ttatgattat
    12181 attgttattg gtggagggag tgcaggtatt gcttctgcga acagggcagc catgcatggg
    12241 gccaaagtat tgttagctga aggtaaagag attgggggaa cctgtgttaa cctaggctgc
    12301 gttcctaaaa aagtcatgtg gtatggcgct caagtagcag atattttagg gacttacgct
    12361 aaggattatg gatttgactt taaagagaaa gcatttgatt ttaaacaatt gaaagcaaat
    12421 cgtcaagctt atattgatcg gattcatgtt tcttatgagc gaggctttga gcagaatggt
    12481 gttaaccgta tttatgatta tgctgtcttc aaagatgctc atacggtaga aattgcaggg
    12541 cagctttata ccgcaccgca tattttgatt gccacaggag gacatcctgt ttttccagat
    12601 attgaggggg cacaatacgg tatcagctcg gacggctttt ttgccttaga tgaggtacca
    12661 aaacgtacgg ctgtggttgg ggcaggctat attgctgtgg aacttgctgg tgttttgcat
    12721 gctttgggat cgaagacgga tttgtttatc cgtcacgatc gacctttaag aagttttgac
    12781 aaaaccattg tggatgtttt agttgaggaa atggcagttg gtggtccctg cttacaccct
    12841 cattcagaag tggcaaaggt tgtcaaaaat actgatgagt ccttgaccct ttacctcaaa
    12901 gatggccaag aagttgaggt tgaccagctc atttgggcta tcggtcgcaa gcctaatcta
    12961 gaaggttttg gtcttgacaa aactggagtg acgttaaatg ataaaggtta tattgagaca
    13021 gatgcctatg aaaacacgtc tgtcaaaggg atttatgcag taggtgatgt caatggtaaa
    13081 ctggctttaa ctccagttgc tgtggcagct ggacgtcgcc tatcagagcg tcttttcaat
    13141 ggcaaaacag acgagaaatt ggactaccaa aacgttgcta ctgtgatttt tagtcaccct
    13201 gttattggct ctgttggctt gtcagaagaa gcagcagtca aacagtatgg gcaagaagca
    13261 gttaaaacat atcaatcacg ttttacgtct atgtttactg ctatcactaa ccatcgccaa
    13321 ccttgtctga tgaagttggt aacagtcgga gataccgaaa aaatagttgg tcttcacgga
    13381 atcggctatg gggttgatga aatgattcag ggctttgcag tagctatcaa aatgggagca
    13441 accaaggcgg attttgataa caccgttgct attcacccaa ctggctcaga agaatttgtc
    13501 accatgcgct aaaaatgtag cctaaggcaa taaaaaatga tgttaacagt ttttgaggaa
    13561 agtcttctaa actgctagca tcgttttttg ttaggtgatt aggggaatat gtttttaaag
    13621 atatttgcgt tgctcagaca atattgcctt acctcggaga taaaataaag tgaccctgta
    13681 acaacaaaga gttcatcaga tgttacggaa ccttgtaacc agtctctgta atcttttacc
    13741 tgtgggtatt tatcaggata atcctctaaa agatttgctt cagggaaatc aaaagtcgtg
    13801 acagatactt caaaagtatc tagttgagcc agcaagtcgg ctaaaggctt acgtttgaga
    13861 cctgcaaaga gaatatgaat aggacgtttg ggaaattctt cttgcagtag agactttaat
    13921 ttagcaatgg aatctggatt gtgagcgccg tctaatagaa gattaggttg aataaattcg
    13981 gaccggccag gccaagttgt tgcctcaatt cctttttgaa tcgtttttgg agatatttta
    14041 ggaaaggatt ttctaagtaa ttgagctgtc ataatggcta aacaggcatt cgctttttga
    14101 tgttgaccta atagtttgag acggagtttg gttaaattca agttatcgtg ttgaaaggaa
    14161 aacgtctttt ctgaaggatt gagcaaaaaa tcttttccta attgatataa gcgtgaaccg
    14221 gctttttggg taacttgttg aaagacttga ctagcctcct gctcaagttg accgataata
    14281 acgggttctt tagctttgat aacttctgct ttttggtgag caatttctgc taggctataa
    14341 cctaaacgtt cttggtgatc aaaactaata gaagggcata cgacggccag agcatgaaaa
    14401 acattggttg cgtcggtttt cccaccaatc cctgcctcaa taatggcaat atcaacaggt
    14461 ttaagattgg caaagtagca aaacattatg agagtcacta actcaaactc ggtaggtcta
    14521 tcccaatttg tttcaaggga cattttagtg agaatgggtc taatcacgct cacacattgc
    14581 gccaattcta ggtctgaaat gggctggcca ttaaggcaaa tccgatcgtg aaaagagata
    14641 ataaaaggag atgtaaaggt tccgacctga taaccagaag ttgacaggat atgctgtaag
    14701 taggctgtca cagagccctt gccgttagtt ccaacaacgt gaatagcagg gaatttgtct
    14761 tgtggccggc ctagtgcctc aagtaaccaa gccattctgg ccaaatcggt cttgcgacca
    14821 ttagccttaa aggtatgaat ccaggaaatg ctatcatagg tagtcattac tatttcttgt
    14881 ccttctaaca atgcttttaa gggttcgtag gaagaccagt attagcatct tcagctccag
    14941 ttgcattagg aagttgcgtc ccttcagtgg ttgatggtgt ctcaggagct gtaggagtag
    15001 tctcgttgtg agaaggtgcg gtagaagatg acggaagagt tgtcttatta tcatctgtgg
    15061 tttctgaagt acctgtatgg ttttgattaa cctgagaaga ctctttttca ataatcttga
    15121 caatggtatt actcgattct ttgggtgtat cattagaggt cttatctggt acaggctgca
    15181 gtgctcttgt aatggtaatg gttgccacaa tgatactcaa aatactacca ataagtgcaa
    15241 tggatttttg gaaagctgta aaacctgttt taatatgctc ggtagggaca cctcctgatt
    15301 tacgaggttt ttgttgacgg gaataacgtg atgacatatt tttctccttt aaaatcatcg
    15361 taatgccaag attaaggagg aggaaacaga agtcctagct cctctttaac acttcatcta
    15421 tcagtataat ctagaaaaaa agtgaagtca acggtttacc ttatgtctag gacaaggaag
    15481 tcctttgggc ttattgtaat acgaatattc ttgatttcat tttagctatt ttgtgataga
    15541 ataaagtatt gagtaaaaat gaaggtgaca catgatttat tttgataatg cagccacaac
    15601 cataccttat ggagaggctc ttaaaactta ccaagaagta gcaacaaaaa tatatggcaa
    15661 tccctcaagt ctgcaccaat tagggacaaa tgcgtctcgc attttagaag cttcccgtaa
    15721 acagattgct ggtttgttgg gtgttaagtc agaagaaatc ttttttacgt ctggtgggac
    15781 tgaaagtgct aattgggcta ttaagggaat tgcttttgaa aaaactgctt ttggcaaaca
    15841 tattattatc tcagccattg aacaccctgc cgtgagtgaa agtgtcaaat ggcttctcac
    15901 acaaggattc gaagtttctt atgctccagt gacaacacag ggagttgttg atgtgaatgc
    15961 tttagctgag ctgattagac cagacaccat cttaatctcg attatggctg ttaataatga
    16021 aatgggagct atccaaccga ttagagccat ttcaaaccta ttggctaacc aaccaacgat
    16081 cacctttcac gttgatgctg ttcaagccat tggtaaaata ccactctgtg attatatgac
    16141 taatcgtgtg gatttggctt ctttttcagg gcacaaattt catagtgttc gtggtgttgg
    16201 cttcctttat aaaaaagcag gcaagcgact caatcctctc ttgtcaggcg gcggccaaga
    16261 gcaggagtta cgttcaacca ctgaaaatgt tgcaggaatt gctagcatgg ccaaagcatt
    16321 aaggatagtc actgaaaaac aagtgagcgt cttacctaaa ctaacagcga tgcgagatgt
    16381 gatttacaaa gctttgtccg cttacccaga tgtgacagta ttttcagctc aagaaggctt
    16441 tgcgcccaat attttgacct ttgggattag aggggttcga ggagaagtta ttgtccacgc
    16501 ctttgaaaaa tatgagattt atatttcgac cacaagtgca tgttcgtcca aagcaggtaa
    16561 gccagcagga agcctagtgg ctatggggat tcctgtaaaa actgcccaga cagccgttcg
    16621 tattagtcta gatgatgaca acgatatggg acaagtagag cagtttttga ccatattcaa
    16681 acagatttat gataaaacac agaaagttag gtaagatgga ctattcagaa attatggttc
    16741 gccatggtga actatcaact aaagggaaga atcgcatgcg attcattaac aaacttaaaa
    16801 acaatattca agacgtactg gctcctttcc cagccattac tgtccgttca gatcgtgata
    16861 ggacctatgt gtctctaaat ggcacagatt atcagcctat tgtagaagct ttaaagctgg
    16921 tgtttggtgt tcaagctcta tctcctgttt ataaacttga aaaaagtgtc cctcttttgg
    16981 taacagctgt tcaagatatc atgacttctc tttatcgtga tggactgacg tttaagattg
    17041 ctactaagcg tagtgatcac gcgtttgaat tggatagtcg tgagcttaac agccttcttg
    17101 gtggagctgt ttttgaggtt ttaccaaata tccaagccca gatgaaacat cccgatgtga
    17161 ctctcaaagt cgaaattcgt gatgaagcag cttacatttc ttatgaagag attaagggag
    17221 caggcgggtt accagtagga acgtcaggga aagggatgct gatgttatcg ggcggtattg
    17281 attcaccagt agctgggtat ttagccctta aacgtggcct tgatattgaa gttgttcatt
    17341 ttgctagccc tccgtacacc agtccaggtg ccttggctaa agcccaagac cttactcgtc
    17401 ggttaactcg ttttggtgga aatatccaat ttatcgaggt tccttttaca gaaattcaag
    17461 aagaaattaa aaataaggca ccagaggctt accttatgac attaacccgc cgctttatga
    17521 tgcgcatcac agatgccatt cgtgagcaac gtaagggtct tgttattgtt aacggtgaga
    17581 gcctaggtca ggttgctagt caaacccttg aaagcatgca gaccattaat gcggtaacct
    17641 caaccccaat tattagacca gtcgtgacaa tggataaact tgaaattatc gagatggctc
    17701 aggtgattga tacttttgac atttctattc aaccgttcga agattgctgt actatttttg
    17761 caccagaccg tcctaaaacc aaccctaaac taggtaatgc tgaaaaatat gaagaacgct
    17821 ttgatattga tggtcttgtc cagcgtgctg tgtcaggaat tgttgtcaca gaaatcacac
    17881 ctgaaatcgt caatgatgag gttgaaaatc tcattgatgc tttactttaa aagaaaagat
    17941 caagtgtaaa tcttttagta gtcagtaatg atactattga aaagcctcta taagggcttt
    18001 tttgctgcaa tgaaggagga aaattttgag gcaagatgtt ataatagaga aaaaggaggg
    18061 tgtgtcttga ttaaaactat gcaatacaaa aaaacgatgg caacagttgt tgctcttatc
    18121 gtcgcacttt tgctatttgg cttgatttat gatttacttg gggttcaaaa aaatgagcta
    18181 gcagctcaaa aatctgctca gccaaaggtc aaaacagcgc gtgttgtagc taatggcgac
    18241 attttaattc atgatattct ctacatgagt gctagaaaag ctgacgatac ctatgatttc
    18301 actccttatt ttgaatatgt taaggactgg attagcggtg ctgacttagc tattggagat
    18361 tatgaaggga ccattagccc agattatccc ttagcaggct atcccttatt caatgctcca
    18421 gaagagattg caggtgctct gaaaaatact ggctatgatg tagtcgattt agcccataat
    18481 catatcttag attcccaatt agacggtgcc cttaacacta aaaaggtttt tcatcaatta
    18541 ggtatagaca gtattggcat ctatgacaag gatcgttcaa aagaatcctt cttaattaaa
    18601 aatgtcaatg gtatcaaaat tgcaatttta ggttattctt atggttataa cggcatggag
    18661 gccacactta gccaagaaga ctatgagaaa cacatgtctg atttagatga agctaagata
    18721 aaaaaagaac ttcagctagc tgaaaaaaag gctgacgtga ccattgtcat gccacaaatg
    18781 ggaacagaat atgccttaga accgacagca gagcaaaaag aactttacca caaaatgatt
    18841 gattggggag ctgacgtcgt cctaggaggc catccgcatg ttattgaacc ttcagagaca
    18901 gttataaaag gtaggcaaaa gaaattcatt atttactcta tgggaaattt tatttcaaat
    18961 cagcggcttg aaaccgtaga tgatatctgg actgagcgtg gcctattgat ggaccttact
    19021 tttgagaaga aagataacaa aacaaaaatt aaaacagttg aggcccatcc aaccatggtt
    19081 ttagccaaag gtaaaggcat tgtgggtaaa gaaggttttg aactatacaa ttatcgaaca
    19141 atggttttag aagattttat caaaggtgga aaataccacg acaatattga tgaggaaacc
    19201 aaagcaaaag tagcacttgc ctatcaggaa attaatgatt tagttaacct gaaatggtaa
    19261 tgtttggtgg tttagcatct aacgataaaa aatagagatt aaacttaatt tttccttgat
    19321 aaaaagcagt tatggtgcta aaatagtaac gttgactaaa tgcacatcct gtgcaaccgc
    19381 gcgaaaattg ttatcaagta gaccaagtct cacgattcca ggcgagtctt cacagaggga
    19441 aacctcaaac aaacatttta taggaggtgc atcatgagca catacgcaat catcaaaact
    19501 ggtggaaaac aagttaaagt tgaagtaggt caagcaatct acgttgagaa aattgacgct
    19561 gaagctggcg cagaagtcac ttttaacgaa gttgttcttg taggtggtga caaaactgta
    19621 gttggtactc cagttgttga aggagctact gtcgttggaa ctgttgaaaa acaaggaaaa
    19681 caaaagaaag ttgtaacatt caaatacaaa cctaaaaaag gtagccaccg taaacaaggt
    19741 catcgtcaac cttacactaa agttgtcatc aacgcaatca acgcttaatt tactagctta
    19801 tgattaaagc aatttttact cgccaaaaaa atggtcaact gagcagtgtt acactgacag
    19861 gtcatgctgg tagtggtaaa catggctttg atattgtttg tgcctctgtt agtactctag
    19921 ccattaactt tgttaattct cttgaggtgt tagcagattg ccaagcatta gtagatctta
    19981 atgatgttga aggtgggtat atggctatta caataccacc acatgacaac aaggaggaag
    20041 ttcaattatt atttgaatct tttcttctag gaatgactag tttggcgaag gactcttcga
    20101 aatttgtcaa cactcaggtc atctaaattt aatttaagag aggaaacaac attatgttaa
    20161 aaatgaatct tgctaacttg caacttttcg cccacaaaaa aggtggaggt tctacatcaa
    20221 acggacgtga ctcacaagct aaacgccttg gtgctaaagc tgctgacggt caaactgttt
    20281 caggtggatc aatcctttac cgtcaacgtg gaactcatat ctacccaggt gtaaacgtag
    20341 gccgtggtgg agatgacaca ctttttgcta aagttgaagg tgttgtacgt ttcgaacgta
    20401 aaggacgcga taaaaaacaa gtttctgttt acccagtagc taaataattg tttaacatcg
    20461 cattatataa ggctttccag gtgtctggaa agccgatttt tttattttgc tactcatttg
    20521 ctacccatat tctaaaagcc gatgtaggaa gagagcttgt cagcagtttt atcttttgag
    20581 gatttagtaa catgagcgta gatattcatg gtagtttgga tagtttcacg accaagtgta
    20641 ttggattttc ttctatccta ctaaagattg tagttgctta tttagagcaa tagttctaat
    20701 tgtaaaaagt cagcataata aaacaatatc ataagatgtt gttataacgg gctttatggt
    20761 ataattaagg atactcattt taggaaggaa agcaatgaat attcaacaat tacgctatgt
    20821 ggtagccatc gctaataatg gaacttttcg agaagctgcc tctaaattgt ttgtcagtca
    20881 gcctagctta tcagtttcta tcaaagattt agaggcggaa ttagggtttc aaatttttaa
    20941 tcggactact tcaggaacag tcttgacaag tcaaggacta gttttttatg agaaagcttt
    21001 agaagtagtc aaatcttttg attcttttga aaaaaccttt tctcaagctg atctggatca
    21061 aaatgaattt tctattgcta gccaacatta tgactttttg ccacctctta ttacagcttt
    21121 ttcgcaacaa tacgatggtc atcgtgtctt tcgtatcttt gaatcaacaa ctattcaaat
    21181 tttagatgaa gttgctcaag gaaacagtga aattggtatt atttacttga atgtagacaa
    21241 tcaaaaaggt ctctttcagc ggatggataa gctgggcttg gaatatgttt ctctaattcc
    21301 ttttactact catatttatc tttcaaaaac gcatccattg gctaatcgcg aagcgcttta
    21361 tttgagcgat attcaaggat tacctgcggt aaggtttacc caagaaaggg acgagtattt
    21421 gtattattct gaaaattttg tggatactag tgaatgccct cgtatttata atgtgtcaga
    21481 tagggcaacc ttgaacggta ttttagagag aaccaatgcc tttgcgacag gatcaggttt
    21541 tctcgatcat cggagtgtta atgggattaa agtgatacct ctagctgatc atattgacaa
    21601 tcaaatgatt tatgtcaaac gaaaagataa aaacctttct gttgctgggg ccacttttgt
    21661 gactatttta aaagactatt ttgataaaag aaggaaggcc ttaacatgaa aaaacgattg
    21721 tttgtgctta gcttgatcct ccttgtagct ttggatcaac ttagtaaatt ttggattgtt
    21781 tctcatatag cgcttggaga agtgaaaccc tttatcccag gtatcgtcag cttgacttac
    21841 ttgcaaaaca atggggctgc cttttccata ttgcaggacc agcaatggtt ctttgttgtc
    21901 ataacggttt tagttatcgg ttatgctatt tattaccttg ctactcatcc ccatttaaat
    21961 atctggaaac aattagctct cttgcttatt atttctggtg gaatcgggaa ttttattgat
    22021 cgtttgcgtt tagcttacgt gattgatatg gttcatttag actttgtgga ttttgccatt
    22081 tttaatgtgg cagattcata ccttaccgtt ggtgtcatat tattagtgat atgtttatgg
    22141 aaagaagagg attatggaaa ttaatgtgat aacatcgggg caacgcttgg ataaggcact
    22201 agctgattta agtcccctgt cacgtggtca agccaatgac caaattaagc aaggccttgt
    22261 tttagttaat ggtcagcaaa aaaaggctaa atatacggtt caagcaggag atgtgatttg
    22321 ttttgaactc cctaaagaag aagtcttaga gtaccaagct cagaatattc ccttggacat
    22381 tatctatgaa gatgatgctc tcgccattat taacaagcca cagggaatgg tagttcaccc
    22441 ttcggcggga cacccttcag gaacaatggt taatgccttg atgtatcata tcaaggattt
    22501 gtcctcaatc aatggtgtgg ttcgtccagg aattgttcat cggattgata aggacacctc
    22561 aggtctctta atggtagcta aaacagatgc agctcatcaa gccttggcag aagaattaaa
    22621 ggctaaaaaa tctctcagaa aatacctcgc cattgtccat ggaaacctac cgaatgatcg
    22681 cgggatgatt gaagctccta taggtcgtag cgaaaaggac cgtaaaaaac aggctgttac
    22741 agcaaaaggc aaagaagcag tgacacgttt tacagtgcta gaacgttttg gcgattacag
    22801 tctagtggaa ttacaactgg aaactggtcg aacgcaccaa attcgtgttc atatggccta
    22861 tattggtcat cctgttgctg gggacccttt atatggacca cgtaagacac tatcaggtca
    22921 tggccaattt cttcatgcaa aaacattggg attaacgcat cctatgacag gaaaagaaat
    22981 gatatttact gttgaagctc ccgaaatttt tcaaaaggtg ttaaagctgc taagaaaaaa
    23041 ataaacagcg aggagtagcc attattttta gtcttatatc tttgtgtaaa gtttttaaca
    23101 ttataaaaaa tactaaaaag catttacgat aagccaggaa atatgagaag tcttttatgt
    23161 tattgggata tgcaacatat ctgttagaga tctttattta aactccttaa agaaaagaga
    23221 tattccaaat agatgctagg tattgtcttt tttacttgtt tttcttttct ttttttgcta
    23281 tactgattga aataaaatat tcctttaaaa cagtcctgtg aggctgtcaa ggagacggat
    23341 taaaaacatg cactatgata cttaattgtg ctatattttg ctgaatctcc ttgtttccaa
    23401 ggagatcttt ttatttgaat ttttagagga ggtttcaaca tgaaaactaa ggaaattgtt
    23461 gatgacgtga ccatgaaacg cgccattacc cgtattactt atgaaattat cgaacgaaac
    23521 aaacaattgg acaatgtggt tttggcagga atcaaaacgc gaggtgtttt tctagctcgt
    23581 cgcattcaag aaagactgca tcaattagaa gggttggatt taccaattgg tgagttagac
    23641 accaagcctt ttagagatga catgagagtt gaggaagaca caactctcat gtcagtagat
    23701 attacaggca aggatgtgat tttgattgat gatgtgcttt atactggtcg taccatccgc
    23761 gcagccatcg ataacttagt gagtttaggt cgaccagccc gtgttagtct agctgttttg
    23821 gtggatcgtg gccatcggga attaccgatt cgcgcggatt acgttgggaa aaatattcca
    23881 acaagcagtg tagaagaaat tgttgttgag gttgtcgaag tcgatggccg tgatcgtgtt
    23941 agcattattg acccaacata agaaagaggt tttactgtga aagatgtcat ttatgatgtg
    24001 gaagaagtgc caaaggcagg tatgttagtt ggtttgtcct ttcagcactt atttgctatg
    24061 tttggtgcga ctgttctggt tcccattcta gttggaattg acccatcagt tgctttgtta
    24121 tctagtggtt taggaaccct tgcccactta tcagtgacca aatttaaaat tccagcctac
    24181 atgggctcaa gttttgctta tatagcagct atgcagttac tgatgaagac aaatggtatt
    24241 ggtgctgtag ctcaaggggc tatgacagga ggtctcgttt acctgattgt agctttgatt
    24301 gttaaagcta ttggcaatga ttggattgat aacatcttac caccgattgt ggttggtccg
    24361 attgttatgg tcattggtct aagcctagct tctacagctg ttaatgatgt catgctaaaa
    24421 aatgggaact ataatctgac ttatcttgtt attgggttag tcaccttatt atcagttatt
    24481 tttttcaata tttatggtaa gggaattgtt gctattgtac caattttatt ggggctatta
    24541 gttggttatg ttgtagccct tttagtgggt gttctcaccg gtcaagaaat tgttgatttt
    24601 accaatgtgg ctcaggccaa atggtttagt atcccatcag tggaaattcc tttcttaact
    24661 tacggggtta aattctaccc aagtgccatt ttaactatgg cacccattgc ctttgttaca
    24721 atgacagaac attttggaca cattatggtc ttaaatagtt tgacaaaaag agattatttc
    24781 aaggatccag gacttgaaaa gactttaact ggtgatggtt ttgcgcaaat cattgccggc
    24841 ttcttagggg cacctccggt cacttcttat ggtgaaaaca tcggtgtaat ggctttgaat
    24901 aaaatattct cggtctatgt tattgcaggt gccgcagtga ttgccgctct cctcagtttt
    24961 atcggtaagg tatcagcctt aattcaatct attccaacac cagttattgg aggtatatca
    25021 gttgccttgt ttggtgtaat agcttctagc ggtttgaaaa tcttgattga atccaaagtt
    25081 gatatggata ataagaaaaa cttattgatt gccagtgtta ttttggtctc tgggattgga
    25141 ggattgatgc ttcaagtaaa tggtcttcaa atttcaggtg tcgctttctc aacacttctt
    25201 ggcatcatct tatatcaggt acttcctgaa aaataggaag aattgttgtt agaccactta
    25261 catagtcatc agtcgttagt gataaagggg ataatcatgt cagttgtaaa taatcgcgtt
    25321 gcacttacta acttagtttc aatggaagca ttaaccaccg aagaagtttt aggtcttatc
    25381 aaccgtggtt cagaatacaa ggctggtaag gttgttattt cggatcatca aaaggatctt
    25441 gttgccaatt tattctttga aaactccacc cgaacccata agtcttttga agtggctgag
    25501 aagaaactcg gcttgacagt tcttgatttc aatgctgatg caagtgcggt taacaaggga
    25561 gaaagtttgt atgatactgt gttaaccatg agtgcacttg gaacagacat ctgtgtgatt
    25621 cgtcacccag aagatgatta ttacaaggaa ttagtagaaa gtccaactat tacagcttcc
    25681 attgtcaatg gaggagatgg ttctggacaa cacccgagtc aatgtttact tgacttatta
    25741 accatctatg aagaatttgg acgctttgaa ggcttaaaga ttgcgatcgc tggtgactta
    25801 actcactcta gggtggcaaa gtctaacatg caaatcctca aaagattagg agcagagctt
    25861 tatttctatg gacctgaaga atggtattca gaagccttta atgcttacgg cacttatatt
    25921 gctattgacc agattattaa ggaattggat gttcttatgt tgctgcgtgt acagcacgaa
    25981 cgtcatgacg gccatcagag tttttcaaaa gaaggttacc atcaagcgtt tggattgaca
    26041 caggaacgtt accaacaatt aaaagatttt gctattatta tgcatccagc tccagttaat
    26101 cgggatgtgg aaattgcaga tagtttggtg gaagctccta aagcgagaat tgtatctcag
    26161 atggctaatg gtgtctttgt tcgcatggct attattgaag ccattttgaa tggtagaaat
    26221 aaaaactcat gatgaaagat taaagcatgt ttagaaggta ggaaaaggta ggaaaatgac
    26281 aaaacgatta cttattttag aagacggcac tatttttgaa ggagaaccct ttggtgctga
    26341 tattgatgtg actggtgaaa ttgtctttaa tacaggaatg acaggctacc aagaatccat
    26401 cactgaccaa tcctacaatg ggcaaatttt aacctttacc tatcctttga ttggaaatta
    26461 tgggattaat cgagatgact atgagtccat ttcacccacc tgtaaagggg ttgttgtgtc
    26521 tgaagtcagt cggttggcaa gtaattggcg caagcaaatg acgctagatg cgttcttgaa
    26581 aataaaaggg attccaggga tttcgggaat tgatacgaga gctttgacca aaattattcg
    26641 gcaacacggt accatgaaag ctacgatggc agatgatgga gatagtatcc agcatttaaa
    26701 agatcaactg cgtgcaacag tcttaccgac taacaccatt gaacaagtgt caactaaaac
    26761 agcttatcct gcaccaggga tcgggaaaaa tattgtattg gttgattttg gtttaaaaca
    26821 ttctatttta agagaatttt ctaaaagaca atgtaatatc accgttgtcc ctttcaacat
    26881 cactgcagaa gaagtgctcc aactaaatcc ggatggcttg atgctatcta atggcccagg
    26941 aaacccagaa gatttgccag aggctttaga catgattcgt ggggtacaag gtaagattcc
    27001 tatttttggt atttgtatgg gacatcaact ctttagtcta gcaaatggtg ccaagacttg
    27061 taaaatgacc tttggtcatc gtggctttaa ccatgccgtt agagaaattg caacgggaag
    27121 aattgatttt accagtcaaa accatggtta tgccgttgaa cgtagtagtc tacctgatac
    27181 tttaatggtt acgcatgaag acattaacga taagacggtc gaaggagtga aacatagaga
    27241 ttttccagct ttttcagtcc aatttcaccc tgatgcggct ccaggacctc atgatgccag
    27301 ctacttattt gacgaatttt tggaaatgat tgattcttgg agatgtacga gtaaatagta
    27361 aatcagttgc aatttcacga ctatatcacc tcttgttact ctatttatta acatttacag
    27421 ttgatttagt accctatcaa aaatattatt taatgttgct ctgtgaggca acaaatagag
    27481 aaaggaaggc aaggagaaca caagtaaata atttagtaaa aagttaggtt ttcaaagaga
    27541 taaagctctt attgagaagt gctgacttta ccgcttcttg tggtattctt ggtatcatta
    27601 attatgccaa aacgaaaaga tattcaaaaa atcatggtta tcgggtctgg cccgattatt
    27661 attggacaag ctgctgaatt tgattatgca gggactcagg cctgtttggc tctaaaagaa
    27721 gaaggctata aggtcatact tgttaattca aatcctgcaa cgattatgac agataaagaa
    27781 atcgctgata aggtatatat tgagcctttg actcttgaat ttgttaatcg tatcattcga
    27841 aaagaaaggc cagatgccat actgccaacc ttaggtggtc aaacgggcct caatatggca
    27901 atggcattat ctaaagctgg tattcttgat gatttagaga ttgaattgtt aggtactaag
    27961 ttatctgcga ttgatcaggc agaagacaga gaccttttca aacaattaat gcaagaacta
    28021 gaccaaccca ttccagaatc tacaattgtt aaaacagttg atgaagctgt tacatttgct
    28081 agagatatcg gttatccagt cattgtgcgc ccagctttta ctcttggtgg aactggtgga
    28141 ggaatatgta gtagtgaaga agaactttgt gaaattactg aaaacggcct aaagttatca
    28201 ccggtcacac agtgtttgat tgaacgctca attgctggct tcaaagaaat tgaatacgaa
    28261 gtaatgcgag atagtgctga taacgcgctg gttgtttgta atatggaaaa ctttgatccc
    28321 gtagggattc acacaggaga ttctattgta tttgcaccaa cacagaccct ttctgatatt
    28381 gaaaatcaaa tgttacgtga tgctagttta aaaataattc gagctctgaa aattgaaggt
    28441 ggctgtaacg ttcagttagc actagatcct tatagtttca aatattatgt tattgaagta
    28501 aatcctagag tgtctcgttc ctctgccctt gcttcaaaag caacaggtta tcccattgcc
    28561 aaattggctg caaagattgc tgttggccta acacttgatg aaatgattaa ccctatcaca
    28621 ggcactactt acgctatgtt tgaacctacc cttgattacg ttgttgctaa aattccgcgt
    28681 tttccgtttg ataaatttga acatggtgaa cgccaactgg gaactcaaat gaaagcaaca
    28741 ggtgaagtca tggctattgg ccgtaatttg gaagagtcct tactaaaagc ctgtcgttct
    28801 ttagaaattg gtgtttgcca taatgagatg acaagtttaa gtaacattag tgatgaagag
    28861 ttagtgacta aagtgattaa agctcaagat gatcgacttt tttacttgtc agaatcaata
    28921 cgacgaggtt atagtatcga agaacttgag agcttgacca agattgattt atttttcttg
    28981 gataaattac ttcatattgt tgaaatagag caagatttac aaatgcatgt tgaccatttg
    29041 gaaagcctca aaaaagcaaa gcgttatgga ttttcagatc aaaaaattgc agaaatttgg
    29101 caaaaggatg aaagtgatat cagagcgatg agacattctc atagcctgta tcctgtctat
    29161 aaaatggtag atacttgtgc agctgaattt gatgctaaaa ccccttattt ttattcaaca
    29221 tatgagttgg aaaatgaatc tgttcagtcg aataaagaat caattttagt tttaggttca
    29281 ggccctattc gtattggtca aggggttgaa tttgactacg caacggttca ttctgttaaa
    29341 gccatccaaa aagctggcta tgaagccatt atcatgaatt caaatccgga gactgtatct
    29401 acagattttt cggtatcaga taaattatat tttgaaccgt taacctttga agacgtcatg
    29461 aatgtgatag atttagagca gcctaaggga gtaatagttc agtttggagg acaaactgct
    29521 attaacttag cacaagcact ttctgaggcg ggtgttacaa tattaggaac acaagtagag
    29581 gatttggata gggctgaaga cagagattta tttgaaaagg cgttgaaaga gcttggaatc
    29641 ccacaaccac aaggtcaaac ggcaactaat gaagaagaag ctttagaggc agctaaaaaa
    29701 attggttttc cagtcttagt tagaccttct tacgtacttg gtggccgggc tatggaaatt
    29761 gttgaaaaca aagaagatct tagagaatat ataagaacag cggttaaagc aagtcctgaa
    29821 catcctatct tagtggactc ttatattttc ggtaaggagt gtgaagtgga tgccatttca
    29881 gatggaaaat cagtcttaat tcctggtatt atggagcaca tcgaaagagc aggtgttcat
    29941 tcaggagatt caatggcagt ttatccgcca cagcaattat ctaagcaaat tcaagaaaca
    30001 atagctgagt atactaaacg tttagccatt gggttaaatt gtattggtat gatgaatgtt
    30061 caatttgtta ttaaaaatga acaagtctat gttattgaag tgaatccacg cgctagtcgt
    30121 accgtacctt tcttatcaaa agtaacaggt attccgatgg ctcagattgc tactaagttg
    30181 attttaggtc aaacattaaa ggatctagga tatgaagatg gtctttatcc ccaaagtcaa
    30241 ctggtgcata tcaaagcgcc tgtgttttca tttacaaagt tggcacaggt tgatagtctt
    30301 ttaggtcctg aaatgaaatc aactggagaa gtaatgggtt cggatactag tcttgaaaaa
    30361 gcactttata aagcgtttga agccaataat tctcatttat cagaatttgg tcaaattgtc
    30421 tttactatag cagatgatag taaggcagaa gctctaagtc tagcaagacg atttaaggcg
    30481 attggctatc aaattatggc tactcaaggt acagcagctt actttgctga gcaaggctta
    30541 agcgcgtgtt tagttggaaa aattggtgat gctgccaatg acatcccgac actcgtgcga
    30601 catggtcacg ttcaggcaat tgttaataca gttggaatta aacgcacagc tgataaagac
    30661 ggacagatga ttagaagttc agctattgaa caaggagttc ctttatttac agctttagat
    30721 actgcaaaag ctatgttaac ggttttagaa agcagatgct ttaacatcga agcgatataa
    30781 aaattaaaaa atcattttta agaaaactta aaaatgattt ttttagatta taatgacaaa
    30841 agtttcagta agctattaat ttgtcatagc atataagtca ttatcttgtg gcttgttttc
    30901 gactaagggc taagaatttc ttgacaacaa tataaaaagg tcatatactt gtcttataca
    30961 aatagtacaa aaggggagga tagaaatgtc taaaagagga aaaattaaaa taacaacgaa
    31021 aacaaagctt attacagcta gtgttataac gctagtatta attataactg gagtagtctt
    31081 gtggaaacaa caacaaaata cgctaacagc tgatatcgct aaagaacctt actctactgt
    31141 tagtgtaact gaagggagta ttgcttcttc gactttacta tcaggtactg taaaggcttt
    31201 atcagaggaa tatatttatt ttgatgctaa taaaggaaat gatgcaactg ttacagttaa
    31261 agtaggtgat caggtaacgc agggccagca attagttcaa tataatacaa caacagctca
    31321 gtcagcttat gatactgctg ttaggagtct taacaagatt ggccgacaaa ttaatcatct
    31381 taaaacatac ggagttcctg ctgttagtac agaaactaat aaagatgaag ctaccggtga
    31441 agagacgaca acaacagttc aaccatcagc tcagcaaaat gctaattata aacagcagct
    31501 gcaagattta aatgatgctt atgcagacgc acaagcagaa gtaaataaag cgcagatagc
    31561 gttaaatgat acagtagtta tcagtagtgt ctctggaact gttgtggaag taaataatga
    31621 tattgatcct tcttcaaaga acagtcaaac acttgttcac gtagcaaccg aaggacagct
    31681 tcaggtgaaa ggaacattga cagagtatga tttagcaaac attaaggttg gtcaatctgt
    31741 aaaaattaag tctaaagttt attctaatca agaatggact ggaaaaatat catatgtttc
    31801 aaactatcca actgagtcta atgcaggttc aacaacgcca gcaggtagca ctggagcggg
    31861 aagttctaca ggagctgcct atgattacaa gattgatatt ataagtcctc tcaaccagct
    31921 taaacaaggt ttcactgttt ctgttgaggt tgttaatgaa gcaaaacagg ccttagttcc
    31981 tttaacggct gttattaaga aagataaaaa acactatgtt tggacttatg atgatgctac
    32041 tggcaaagcc aaaaaagtag aggtgacact tggaaacgca gatgcacaac aacaagaaat
    32101 tcataaagga gtagctgttg gtgacattgt tattgccaat ccagataaaa atatcaaacc
    32161 ggataaaaaa ctagaagggg ttatttcaat aggtaccaac acaaaaccgg aaaaagattc
    32221 tcaatcaaag aataaaaaat caggggtgga taaatagtgt cgcatgaaaa aaaacaatta
    32281 atgcaattat caaatattgt gaagagctat caaaatgggg atcaagttct taaagttttg
    32341 aaaggtatta atttaacagt atatgagggt gaatttttag ctattatggg tccgtctggc
    32401 tcgggaaaat caacactaat gaatattatt ggtttattag atcggccaac atccggagat
    32461 tacacattac ataatactaa aatagaaatc cttaatgatc gtgagttagc aaaagtacga
    32521 aatgatgaaa tcggctttgt ctttcaacaa ttctttctgt tagctaaatt aactgcatta
    32581 caaaatgttg agttgcctct tatttatgct ggtgtaaacg tctcaaaaag acgtgaacag
    32641 gctaagcaat ttcttgaaaa agtaggactt ggacgacgta tcaaacatct accgtcagaa
    32701 ctgtcaggag gtcaaaagca aagggtggct atcgcacgag ctttagtaaa tgacccatct
    32761 attattttag cggatgaacc aacaggtgca ctagatacta aaacaggtca gcaaattatg
    32821 gaactcttga cagagttaaa caaagaaggt aaaacaatta ttatggttac tcatgaacca
    32881 gaaattgctg attttgcaac tcggaaaatt attattcgtg atggtgatat cacaacggat
    32941 actacagcta gtgttgttat tgactaggag gaaaaataat ggaaaattgg aaattcgctc
    33001 ttagctcaat ttgggggcat aagatgcgct caatcctgac aatgttggga attatcatcg
    33061 gtgtagcagc agttgtgatt attatggggt tgggaaatgc tatgaaaaat agtgtaacaa
    33121 gcacattttc tagcaagcaa aaagatattc aactctattt tcaagaaaaa ggagaagaag
    33181 aagacctgta tgccggattg cacacgcatg aaaataatca cgaagtgaag ccagagtggt
    33241 tagaacaaat tgttaaagat atcgatggta ttgattctta ttactttacc aattctgcta
    33301 cttctactat ttcgtatgaa aaaaagaaag tagacaatgc ttcgatcata ggggtaagta
    33361 aagattattt taatataaaa aactatgata tcgtagctgg tcgtacacta acagataatg
    33421 attattctaa tttttcgcgt atcattcttt tagatacagt attagccgat gacctatttg
    33481 gcaaaggtaa ttataagtca gctttaaata aagtggtaag tttatctgat aaagattatt
    33541 tagttattgg tgtttataaa actgatcaga cgccagtttc ttttgatgga ttatcaggcg
    33601 gcgctgtcat ggcgaatact caggtagctt cagagtttgg caccaaagag ataggatcta
    33661 tctacattca tgtgaacgat attcaaaaca gtatgaactt aggaaatcaa gcagctgata
    33721 tgctaaccaa catatcgcat attaaagatg gacagtacgc tgtccctgat aatagcaaaa
    33781 tcgttgaaga aatcaatagt cagttcagta tcatgacaac agtcgtaggt tcaattgcag
    33841 cgatctctct tttagtggga ggaattggtg ttatgaatat tatgttggta tctgtcacag
    33901 agcgaactag agaaattggt ttacgtaaag cacttggtgc aacacgcctg aaaattttat
    33961 cacaattttt gattgaatcc gttgttctaa cagttcttgg aggcttgata ggattattat
    34021 tagctcaatt aagtgtaggg gctttaggaa atgcgatgac attaaaagga gcttgtattt
    34081 ctcttgatgt ggccttaata gcagttttat tttctgcctc aataggtgtc ttttttggaa
    34141 tgttgccagc taataaagct agtaagttag atccaattga ggcattacgt tatgaataga
    34201 atagttcgta tcaattaatc tatagacgct gactagttta acgtctgatt atacctagtt
    34261 tttgtattag cacagtagtt atatcattga agtgttagtg cattttttga ggtgataata
    34321 tctagcaaag ctatcattgg tatgatgatg tggatagcgt ataagtgata catctcttat
    34381 ttctagctga acttcggttc ggctaggaag ttgtcaggca atgagttgtt taaaataaag
    34441 gagattagtt caatgacatt tttatctgat ttgatatcat taatgacaaa aatcagatta
    34501 tcttgggtaa taaaggcggg tatttttcaa ttattatttg taacgattgc taatattgtc
    34561 ttatcagaat ttttctattt tatattagac gttactggtc aatatcattt agataaagac
    34621 aatgttgtga cttttttaaa aaatcctata gcacttgctt tattaggtgc ctatttattt
    34681 ttattagctg cttttattca ccttgagttt tttgctctat atcgaattat tgcggatcaa
    34741 gaaattagtt tctatctttt tagaaaacag ttttcttatt acctaagggg gctttggaaa
    34801 acattttctg gttaccaatt attacttttt ttgctttata tcctattgac tattccagtc
    34861 ttacatattg gtttatcttc tgtgattact caaaagcttt atcttccaga atttattgtt
    34921 ggggaattat caaagataac tagcacaaag tacttgcttt atggcagtct tattcttgtg
    34981 ttttacctta acctaagatt agtatatttt ttaccattga tagcaatcaa ccatcgtacg
    35041 gttgctcaag catggagaga gagttggcaa aagactaaaa agaaacatgt attgttatgg
    35101 atgaaacttt ttgcaatcaa tggtcttacg attgtagtct tatcgctagc tatttccatg
    35161 attcttattt ttgttgatat gtttaatcct aaggggaata atattattgt tcagctggga
    35221 gctttgacct ttacatggga actcattttt tttactacta ttttttttaa actctgttca
    35281 gcaatgattt taaaagaggc aattgaacca caaaagcaat atgatgagcc aagaagaagt
    35341 aataaggcat atgttgtaat ctttatcgtg gttacagtag gttttgctta tcaatctctt
    35401 gaacgtttaa ctttttttga cacatctcac tctaagacag ttatcgcgca tagaggactt
    35461 gtatcagcag gtgtagaaaa ttctctggaa gcccttgaag gtgctaagaa agcaggaagt
    35521 gattatgtag aactggatct aatcttgact aaggataatc actttgtggt gtctcatgat
    35581 aatcgattga agcgtttagc tggagtaaat aagacgattc gcaacttaac cttaaaagaa
    35641 gttgaacatc taacgagtca tcaaggacat ttttcagggc gttttgtttc ttttgacact
    35701 ttttatcaaa aggctaagaa gttgaatatg ccattactta ttgaactcaa gccaattggt
    35761 acagaacctg gaaattatgt cgatttgttt ttagaaactt atcatcgact tggtataagc
    35821 aaagataata aagtcatgtc tttagattta gaagtaatag aagctatcaa gaaaaaaaat
    35881 ccatcaatta cgactggtta tatcatacca attcaatttg gattttttgg agatgaattt
    35941 gttgatttct atgtcattga agacttttct tatcggtctt atttgtcgtc ccaagctttt
    36001 tggaataata aagaaattta cgtttggact attaatgatc ccaagcgcat agagcattat
    36061 ctcctaaagc ctattcaggg aattattaca gatcaaccag ctttaactaa tcaattgatt
    36121 aaagacttaa aacaagataa ttcttatttt agtcgattag tcagaattat tagtagtctt
    36181 tattaaaggt ttaaagaaag tgtcaagaaa aaaacttgac actttcttta aactgagtta
    36241 tactgtttaa cataggaatt tagcgtagct gtatttctta tacattacta aaagaaaaga
    36301 gactatttaa aaatggcagt aaaaatccgt ttaactcgta tgggttctaa gaaaaaacct
    36361 ttctaccgta ttaatgttgc agattcacgt gcaccacgtg atggtcgttt tatcgaaaca
    36421 gttggaacat acaacccatt agtggctgaa aatcaaatta ctattaaaga ggatcgtgtt
    36481 cttgagtggt tatctaaagg agcgcagcct tctgataccg ttcgtaacat cttgtctaaa
    36541 gctggtgtta tggctaagtt ccacgaccaa aaattctcta aataataaca gcctatggat
    36601 accattgaaa atcttattat cgctattgtg aaacctttga tttcacaacc agataatctt
    36661 accattaaaa ttgaagatac tcctgacttt ttagagtatc atcttgactt ggatgctcaa
    36721 gacatcggtc gtgttatcgg caaaaaaggt cgaactatta ctgcgataag atcgattgtc
    36781 tactcggttc caacactagg aaaaaaagtt cgcttagtta ttgatgagaa ataatcacta
    36841 acttgagatg gattgaaaag cttgttgact taaagtcaac aagctttttg aatagcaaaa
    36901 atcttaatat ttctgaaatg aaaagattag atttttctgt ctttaactaa aaagaagtta
    36961 aagaatggct tagctgattg cctttataag agattatact ggtttttgat agctgctgtc
    37021 atgtaaaata gctacaattc atcttacgag attgacctta gcattgccag tgcagtcttt
    37081 attttccaac ctgctgtttg ttgtatgttt atagtttcct aaaaaatgct ctctcagttt
    37141 tttgggggac attcctaaaa ttaagtatac ttaattttag gaatgtttat attctttaca
    37201 ttctgatgaa aatacaaatt atcctaacat gatgtattga aaggggaaat agtttatgtt
    37261 agtatactga ttaagtgaag ctgtaatgag gcttatacga tcaaaaaagt tagagtaact
    37321 ttataaaaca gtggtgttga agcaagttta gcttcttctc agaaatagat tatctataaa
    37381 aaatcccaaa agtagtttgt ttccagttaa tgaacttctt ttgggaaggc ttttttgctg
    37441 atcgccactt cacttgtata tcgggaacat tcacgctaag atgtataagt tgaatcgttt
    37501 gtctatggct tgatgaaaat taatcaaaag ataatgttca actctataat tagtacaagc
    37561 aaaatgagat aacttattca ttagtaagca taagatataa caagagaaat taccttaaaa
    37621 caggaagtac tagagtattt aaaataagtg atagacttgg atattattag gtcgactagt
    37681 gtccttttca ataatttaat atcgttatta ttagtatcag ccaatcaaat gtggataagt
    37741 tggcttttag aaaggtttta ccacaatgaa gaaacatctt aaaacagttg ccttgaccct
    37801 cactacagta tcggtagtca cccacaatca ggaagttttt agtttagtca aagagccgat
    37861 tcttaaacaa actcaagctt cttcatcgat ttctggcgct gactacgcag aaagtagcgg
    37921 taaaagcaag ttaaagatta atgaaacttc tgaccctgtt gatgatacag tcactgactt
    37981 attttcggat aaacgtacta ctcctgaaaa aataaaagat aatcttgcta aaggtccgag
    38041 agaacaagag ttaaaggcag taacagagaa tacagaatca gaaaagcaga tcacttctgg
    38101 atctcaacta gaacaatcaa aagagtctct ttctttaaat aaaagagtgc catcaacgtc
    38161 taattgggag atttgtgatt ttattactaa ggggaatacc cttgttggtc tttcaaaatc
    38221 aggtgttgaa aagttatctc aaactgatca tctcgtattg cctagtcaag cagcagatgg
    38281 aactcaattg atacaagtag ctagctttgc ttttactcca gataaaaaga cggcaattgc
    38341 agaatatacc agtagggctg gagaaaatgg ggaaataagc caactagatg tggatggaaa
    38401 agaaattatt aacgaaggtg aggtttttaa ttcttatcta ctaaagaagg taacaatccc
    38461 aactggttat aaacatattg gtcaagatgc ttttgtggac aataagaata ttgctgaggt
    38521 taatcttcct gaaagcctcg agactatttc tgactatgct tttgctcacc tagctttgaa
    38581 acagatcgat ttgccagata atttaaaagc gattggagaa ttagcttttt ttgataatca
    38641 aattacaggt aaactttctt tgccacgtca gttaatgcga ttagcagaac gtgcttttaa
    38701 atcaaaccat atcaaaacaa ttgagtttag aggaaatagt ctaaaagtga taggggaagc
    38761 tagttttcaa gataatgatc tgagtcaact aatgctacct gacggtcttg aaaaaataga
    38821 atcagaagct tttacaggaa atccaggaga tgatcactac aataaccgtg ttgttttgtg
    38881 gacaaaatct ggaaaaaatc cttatggtct tgctactgaa aatacctatg ttaatcctga
    38941 taagtcacta tggcaggaaa gtcctgagat tgattatact aaatggttag aggaagattt
    39001 tacctatcaa aaaaatagtg ttataggttt ttcaaataaa ggcttacaaa aagtaaaacg
    39061 taataaaaac ttagaaattc caaaacagca caatggtgtt actattactg aaattggtga
    39121 taatgctttt cgcaatgttg attttcaaaa taaaacttta cgtaaatatg atttggaaga
    39181 agtaaagctt ccctcaacta ttcggaaaat aggtgctttt gcttttcaat ctaataactt
    39241 gaaaactttt gaagcaagtg acgatttaga agagattaaa gagggagcct ttatgaataa
    39301 tcgtattgaa accttggaat taaaagataa attagttact attggtgatg cggctttcca
    39361 tattaatcat atttatgcca ttgttcttcc agaatctgta caagaaatag ggcgttcagc
    39421 atttcggcaa aatggtgcaa ataatcttat ttttatggga agtaaggtta agaccatagg
    39481 tgagatggca tttttatcaa atagacttga acatctggat ctttctgagc aaaaacagtt
    39541 aacagagatt cctgttcaag ccttttcaga caacgccttg aaagaagtat tattaccagc
    39601 atcactgaaa acgattcgag aagaagcctt caaaaagaat catttaaaac aactggaagt
    39661 ggcatctgcc ttgtcccata ttgcttttaa tgctttagat gataatgatg gtgatgaaca
    39721 atttgacaat aaagtggttg ttaaaacgca tcataattcc tacgcactag cagatggtga
    39781 gcattttatt gttgatccag ataagttatc ttctacaatg gtagaccttg aaaagatttt
    39841 aaaactaatc gaaggtttag attattctac attacgtcag actactcaaa ctcagtttag
    39901 agacatgact actgcaggta aagcgttgtt gtcaaaatct aacctccgac aaggagaaaa
    39961 acaaaaattc cttcaagaag cacaattttt ccttggccgc gttgatttgg ataaagccat
    40021 agctaaagct gagaaggctt tagtgaccaa gaaggcaaca aagaatggtc agttgcttga
    40081 aagaagcatt aataaagcgg tattagctta taataatagc gctattaaaa aagctaatgt
    40141 taagcgcttg gaaaaagagt tagacttgct aacaggatta gttgagggaa aaggaccatt
    40201 agcgcaagct acaatggtac aaggagttta tttattaaag acgcctttgc cattgccaga
    40261 gtattatatc ggattgaacg tttattttga caagtctgga aaattgattt atgcacttga
    40321 tatgagtgat actattggcg agggacaaaa agacgcttat ggtaatccta tattaaatgt
    40381 tgacgaggat aatgaaggtt atcatgcctt ggcagttgcc actttagctg attatgaggg
    40441 gctcgacatc aaaacaattt taaatagtaa gcttagtcaa ttaacatcta ttcgtcaggt
    40501 accgactgca gcctatcata gagccggtat tttccaagct atccaaaatg cagcggcaga
    40561 agcagaacag ttattgccta aaccaggtac gcactctgag aagtcaagct caagtgaatc
    40621 tgctaactct aaagatagag gattgcaatc acacccaaaa acgaatagag gacgacactc
    40681 tgcaatattg cctaggacag ggtcaaaagg cagctttgtc tatggaatct taggttacac
    40741 tagcgttgct ttactgtcac taataactgc tataaaaaag aaaaaatatt aaattgattt
    40801 aaggagaaaa aatgataaca caagaaatga aagatcttat taataaccaa ttagcaatgg
    40861 ttgcgacggt tgatgccaaa ggtcaaccca atattggtcc aaaacgttct atgcgtctct
    40921 gggatgataa aacatttatt tataatgaaa atacagatgg tcaaactcgt attaacattg
    40981 aagataatgg gaaaattgaa attgcctttg ttgatcgtga gcgcctttta ggttacaggt
    41041 ttgtaggaac tgctgaaatt caaacagaag gtgcttatta cgaagcagcg aaaaaatggg
    41101 cacaaggacg catgggggta ccaaaagcag ttggtattat tcatgtcgag cgtattttta
    41161 atttacaatc tggtgctaat gcaggtaaag aaataaacag tgaaagtaac taaaattaac
    41221 tgtaacagta tttaggaccc ttattttaaa cgctaaaaaa caagcatact cttttttaca
    41281 gcatagtgac tatgttgtaa aaaggggtat gcttattagg tgctcttaat atttctagat
    41341 aactgcacct aataagtttt caatagactt atagcacatt agttgacttc aatattagaa
    41401 agagaagaac agtgatgttg gtgttcgttt aaagaagtat cgatttccac agtgattgag
    41461 tttatattgt acctttgaca aatcagtcta atagattttt tgcaatgttt ttcagtggta
    41521 gattctctca agcagcaatg tatagttgct ctatgatcaa taccatccat cgaccaaaca
    41581 ttaagctgat taacagacac tatatgagga agttggctga gttcatggtg caaagtgcaa
    41641 tagtctatcg aatcaggaac accatctaaa aaaatgttag cagttgctac taactttgga
    41701 agagctttag ataatataaa agaagcaatg gcaattgata ataaaggatc aagaatgtac
    41761 caaggtttcc attttaagat cagtgacagt atgataatgg ctaaccaccc aaggatatct
    41821 tctaaaaagt gaaggcttaa tatttcttca ttttttgtct ggttagagtg aatgatgaag
    41881 ctagcaaatc cattgattat aattgcaaaa atagctaaaa cgaacatacc gtcataatta
    41941 acaatagtag gatgccataa ttttggtatc gtttcaatca ttactaataa tgatccgcta
    42001 ataagtatta gatttgtcgt tagtgctcct aaaaggctaa atcgcttata gcctagtgaa
    42061 aaatttggac tctctttttt aacagccttt ctttctaaga tagctgagat accaatagca
    42121 atggcatctc caaaatcgtg gacagcatct gctaaaatag cacccgaaaa gaataatgtt
    42181 ccaaaaataa attcaatgag ggaaaaacta agatttaata taaaaataat ggtgactttt
    42241 ttacttgctg gcataatttt ctccttttgt tatactggta atatgtatag tagaattctt
    42301 tattctatta tctaaaaatt aaaatacaat tactataacc aaaaatgagc acctgttcaa
    42361 tagtgaacaa catttagaaa gtgtccgata tgacaaaaga cagacaaatc aaaaaaacaa
    42421 aaacagctat ttatagtgct tttattgctt tattacaaaa aaaagaatat tcgaaaataa
    42481 ctgttcgaga tatgattaca cttgctaatg tagggagatc aaccttttat gcacattatg
    42541 aaagcaaaga aatgttacta aaagaactct gtgaagaact ttttcatcat ttgtttaggc
    42601 aaaaaagaaa tgtgactttt gaggactatt tggtgcatct tttaaagcat tttgaacaaa
    42661 ataaagacag cattgcgacg ttgttacttt ctaatgatcc ctatttttta ttaagattta
    42721 aaaacgaact agaacatgat gtttacccta acttgcgctg caagtatatc gacaaaacga
    42781 ctattccaga agtattccta aaacaatttg ttctatctag ttttatagaa accttaaaat
    42841 ggtggctcca tcaaaggcaa aggatgtctg caaatgaact attaaagtat tatttagagc
    42901 tcataaaata atgactagtg agtcatcttg ccaaattcaa ttttttaata cagacggatt
    42961 ttaacaattt aacagagaaa gacaaaactg taagtgcaaa atagactata acgtgataaa
    43021 ataataggta atttggttct gaaaaagaag tgtctatcaa actttagaat caagagaggt
    43081 cgctaaagtg acgtgagata aagagttaac gatttaggag ctaccatgga atattttaat
    43141 gttggaaaaa ttgtcaacac gcaaggcctg caaggagaga tgcgcgtgtt atctgtcagt
    43201 gattttgctg aggaacgctt taaaaaaggc tcacaattag ctttatttga tgataaagat
    43261 cggtttgttc aagaggtgac aattgttagt caccgtaaac aaaagcattt tgatatcatc
    43321 aaatttaaag acatgtatca tattaatgct attgaaaagt acaagggata cactttaaag
    43381 gtctcaaaag acaatcaagg ggatttacaa gaaggagaat tttattacca tcagattatt
    43441 ggcatggctg tttatgaaaa ggatgtcctt attggacatg ttaaggaaat cttgcagcca
    43501 ggtgctaatg atgtttgggt agtgaaacgc caaggaaaac gagacttgct cttaccatat
    43561 attcccccag tagttcttaa cgtagatgtt cctaacaagc gcgtggatgt tgaattgatg
    43621 gaaggcttag acgatgaaga ttgatatttt aacccttttt cctgaaatgt ttgctcccct
    43681 agaacattcc attgtaggca aggcaaaaga aaaaggatta cttgacattc actaccataa
    43741 ctttcgagat tatgctgaaa aagctcgtca tgtggatgac gaaccctatg gtgggggcca
    43801 aggcatgtta ttgagagcgc agcccatttt tgacaccatt gaacagattg aagccaaaaa
    43861 accaaggatt attcttttag atccagcagg taaacccttt actcaggctt atgctgaaga
    43921 attagctctt gaggaagagt taatttttat ttgtggtcat tatgaaggtt atgatgagcg
    43981 gattaagatc ttggtgacgg atgaaatttc attaggcgac tttgtattaa caggaggtga
    44041 gttggcggcc atgactatgg tagatgcgac cgtcaggtta attccacagg tacttgggaa
    44101 agaaagtagc catcaggacg attctttttc atcaggactt ttagaatacc ctcaatacac
    44161 aagaccttat gattatcgtg gtatgacagt tccagatgtt ctaatgagtg gtcatcacga
    44221 acgtattcgc ttgtggcgtc tagaagaaag tctcaaaaaa acttatttaa ggcggccaga
    44281 tttacttgaa cattacaatt ttgccgagga agagcgcaag ctattggata agattaaaga
    44341 agcattgggt caaggagaag attagtgaaa gataaagcat atgatattac gattattggt
    44401 ggtggtccaa taggtttatt tgcagccttt tatgcaggtc ttaggggcgt aacagtaaag
    44461 attattgaga gtttgtcaga acttggtgga cagcctgcca ttctttatcc tgagaaaatg
    44521 atttatgata ttccagctta tccatcttta acaggtgctg agttgacaga aaatttaata
    44581 aaacaattga gccgttttga agatcgtaca accatttgtt taaaagaaga agtattaacc
    44641 tttgacaagg ttaaaggtgg tttttcgatt aggactaata aggcagagca tttttcaaaa
    44701 accattatca ttgcttgtgg aaatggcgct tttgcaccaa gaactttagg gttagaaagt
    44761 gaggaaaact ttgctgatca taaccttttt tataatgttc accagttgga ccagtttgcg
    44821 ggacaaaaag ttgtgatttg tggtggtgga gattcagcag ttgattgggc tttggcttta
    44881 gaagatattg ctgagagtgt gacggttgtg caccgtcgtg atgctttcag agcacatgaa
    44941 cacagtgtgg aattattgaa agcatcaacg gtcaacctct taacacctta tgtgccaaaa
    45001 gcattgaaag gaattggaaa cctggctgaa aaattagtta ttcaaaaagt gaaagaagat
    45061 gaagtgttag aacttgaatt ggacagtctt attgttagtt ttggtttttc aacttctaat
    45121 aagaatttga aaaattggaa tctcgactat aagcgttcaa gtattactgt ttcaccactt
    45181 tttcaaacaa gtcaagaagg tatttttgcc attggtgatg cagccgctta taatgggaaa
    45241 gtggatttga ttgctactgg ttttggcgaa gcaccaacag cagttaatca ggccattaac
    45301 tatatttatc cagatcgaga taaccgtgtg gtgcattcaa cctctttaat tgactaaggg
    45361 agtcggaagt ttcaagagca gtagcaacag ctaatattca gtttgtcagg agaggacaaa
    45421 tggtttttac ctaagtcttc gtgacaagtt ttatactttg tgataaaata gtcattgtga
    45481 aaaaagtgtg atggttttca cagattaaca cattacaatg aaaaggggtc tatcatgaca
    45541 acaacagata aagagacatt tagttctttt atgaataagg tcttggctgg tacagcgatt
    45601 gctatcgttg tggcactcat tccaaatgct attttagcga ctttcttaaa accgcttttg
    45661 ccaaacatgg cagctgctga atttttacac attgtgcaag tcttccaatt cttcacgccg
    45721 attatggctg gtttcttgat tgggcaacaa tttaagttta atcctatgca acagttggct
    45781 gttggtggag ctgcttatat cggttctggg gcttgggctt atacagaagt cattcaaaaa
    45841 ggtgtggcga caggaacatt ccaacttaga ggtattgggg atctcatcaa tatgatgatt
    45901 acagctagcc ttgcggtttt agctgtgaaa tattttggga ataaatttgg ctctttaacc
    45961 attatcttgt tacctatcac tataggaact ggcgtaggtt atattggttg gaaatttttg
    46021 ccttatgtgt cttacgtgac aaccctgatc ggacaaggga ttaattcttt tacaacctta
    46081 caacctattt taatgtctat tttaattgca gttgctttct cgcttatcat tgttagtccg
    46141 atttcaactg ttgcaatcgg tttagctatt gggcttaatg gaatggctgc gggagcagct
    46201 tctatgggaa ttgcatcgac agcagcagtc ttagtgtggg cgacgcttaa agttaataaa
    46261 tctggtgtac caattgctat cgcacttggg gctatgaaaa tgatgatgcc aaacttcttg
    46321 aaacatccta tcatggctat tccgatggtg ttcactgcag caattagctc attaacagta
    46381 ccattgttta atcttgttgg aacaccagct tcatctggtt ttggcttagt tggtgcagta
    46441 ggtccgattg cttctttagc aggtggtagc tcaatactta ttattatcct tgcttggatc
    46501 attgttccgt ttgcggttgc ttttgcggcg cataaggttt ctaaagatat tctaaaactt
    46561 tataaagaag acattttcgt ctttgaaggc taataggagg aaaatatgtt agtttatatt
    46621 gctggctcag gagccatggg gtgccgtttt ggttaccaaa tttcaaaaac aaataacgat
    46681 gtgattttgt tagataactg ggaagatcat atcaatgcca ttaaagaaaa cgggttgatt
    46741 gtaacaggtg atgtggaaga aacagttaag ctccctatta tgaaaccgac tgaagccact
    46801 caagaagccg atttgattat cttgtttaca aaagcaatgc agttgccaca aatgcttcaa
    46861 gacgttaaag gcattattgg aaaagaaacc aaagtgcttt gccttttaaa tggtcttgga
    46921 cacgaagacg ttattcgtca gtacattcca gagcacaaca ttttgatggg ggtcactgtc
    46981 tggactgctg gtctagaagg tcctggtcgt gctcatcttc aaggtgtggg agcacttaac
    47041 ttacaaagca tggatccaag caatcaagaa gctggacacc aagtggctga tttgttaaat
    47101 gaagctaact tgaatgcgac ttatgatgag aatgttgtgc caaacatctg gcgaaaagct
    47161 tgcgtgaatg gtaccatgaa ctcaacttgt gcccttctag attgtacaat tggtgaatta
    47221 tttgccagtg aagacggtct caaaatggta aaagagatca tccatgagtt tgttatcgtt
    47281 ggtcaagcag aaggtgtcga actaaacgaa gaagaaatca cacaatatgt aatggataca
    47341 tctgttaaag ctgctcacca ttacccatca atgcaccaag accttgtgca aaatcaccga
    47401 ttgactgaaa ttgattttat caatggtgca gtcaatacca aaggtgaaaa gcttggtatc
    47461 aatactccat actgccgtat gattacagag ctagttcacg ctaaagaagc agtgttgaac
    47521 atccaataaa cgctatcaaa tcgttatact caatattatg gctaaagctt taatattgag
    47581 ttttttgtta tgctgatagt atttttctta ggcgtcatta tttgtgagcc tagattatga
    47641 gttaataaaa gaaataataa ttggtagaat ttgatagatt ttgaaaggtt atgcttgact
    47701 tttagttata aaatagtata ataattgtaa acgatttcag ttaggggtgg ttctatctta
    47761 aaatcaaaac gaaaacaatt aatcatggca aagatcactg aagaaaacta tgtttcttta
    47821 gaggatttaa tgcaattact caactcctct gagtctacta tccgtagaga tctaggagag
    47881 ttggagcaag aaggacggct acatcgtgtt catggaggtg ctgaactttt tcactcttta
    47941 caggaggaac tttctaacca agaaaagtct gtcaaaaaca gtcatattaa aaaagctatt
    48001 gcgcaaagag cctctcagtt tatctatgac aacgatgtga tctttattga tgctgggaca
    48061 acgactgaat ttttattacc ttttttacaa gctaaaaatt taactgtagt tactaattct
    48121 attcatcatg ctgctagctt agttgaactc tctattgaga cgatcattgt aggtggttat
    48181 gtcaaacaaa cgaccgatgc cagtattggt aatgtagctt tggaacagat taggcagatg
    48241 aattttgaca aggcatttct tggaatgaat ggtgttgatg attcttatct gacgactcct
    48301 gatatggaag aagcagttat taaaaaagcg gttctgtcaa atgcaaaatt agcttacatt
    48361 ttagtagatg gcactaaaat tggtcaggta tcgtttgtaa aagtagctcc tattaatgat
    48421 gtgactatta ttacattagg aggatcagca agtattctta aacaaataaa ggaaaaggca
    48481 aaggtgattg aattatgatt tataccgtga ccttaaaccc ttctattgac tttattgtca
    48541 gaattgacca aataaatctt gggtcagtga atcgcatggc gagtgatgat aagtttgctg
    48601 gaggtaaagg cattaatgtg agtcgtatct tgcaacgttt agacattgct agcacggcga
    48661 cagggttctt gggtggtttt acaggacgtt ttatcgaaga aagtttgagt gcagaaggcg
    48721 ttaaaactga ttttgtaaaa ggtgatcaag atactcgaat caatgttaaa atcaagtcac
    48781 aagaagagac cgaattaaat ggtcaaggac ctatcattag tcaggaacaa ctggaggatt
    48841 tgaaaactaa gctttcccag ctaacagcag aggatacagt tgtctttgca ggttcagcgc
    48901 cagctaatct tggcaatgct gtttataagg aattacttcc tttagttagg caaagcggtg
    48961 ctcaggtggt ttgtgatttt gaaggacaga ctttaataga tgcgcttgca tataatcctc
    49021 tgttggttaa acctaataat catgaactag aagctatttt tggtacgatt ctgaccagtc
    49081 ttgatgatgt tgaaacctat gcccgtcgtc ttttagagat gggtgctcaa aacgtcatca
    49141 tttcaatggc tggtgatggt gctttgctgg ttactaaaga agcgacttat tttgctaaac
    49201 cgattaaggg agaagttaaa aattctgtcg gtgctggtga ttcgatggtt gctggcttta
    49261 caggcgaatt tatgaagagt caaaatccaa tagaagcctt aaaatggggc gtggcttgtg
    49321 gtacagcgac ggctttctct gatgacttgg cgacaattgc atttattaag gaaacatatc
    49381 ataaagttga ggtagaaaaa cgatgaaaat tcaagattta ttgagaaaag atattatgat
    49441 tctcgattta caggctattt ctaaagaagt tgccattgac gagatgatta ctaaattagt
    49501 tgaaaaagat attgtacatg attttgatgt ctttaaaaag agtatcatga cacgtgaaga
    49561 acaaacatca acagggcttg gtgatgggat tgccatgcct cattctaaaa atattgtagt
    49621 agataaacca gcggtcttgt ttgcgaaatc aaataaaggt gtggattata aggctttaga
    49681 tggtcaacca acggatctct tctttatgat tgctgcgcct caaggagcaa atgatactca
    49741 cttggctgcg ctagcagaat tatcacaata ccttttgaaa gacggctttg ctgataaact
    49801 tcgtgctgca gcgacaccag aagcagtcat tgctgttttt gatgaagcgt caacagctaa
    49861 agaagaagtg gttgctccaa caagtggtca agactttatc gttgctgtta cagcttgtcc
    49921 gacaggaatt gctcacactt atatggcaga agaggctttg aaaaaacaag ctgcagaaat
    49981 gggagtagct attaaagttg aaacaaacgg tgcttctggt gtggctaatc gtttaaccgc
    50041 tgaagatatt cagagagcta aaggagttat tgttgcagct gataaagcgg ttgaaatgga
    50101 ccgttttgat ggtaaacaat tcattgctcg ccctgttgca gatggtatca agaaaagtca
    50161 ggaattgatt tctttgattt taaacaatga aggaaacact tatcatgcta aaaatggaaa
    50221 atctgaaaca gcagtatcaa ctgagaaaac aagtttaggc ggtgctttct ataaacactt
    50281 gatgggcggt gtctcacaaa tgttgccatt tgttattggt ggcgggatta tgattgctct
    50341 agcattttta ttggataaca tgcttggtgt gccaaatgat cagcttggaa gtcttggatc
    50401 ctatcatgaa atagcagcta tttttatgaa cattggtgga gcagcctttt ccttcatgtt
    50461 accagtacta gcaggttata tcgcttattc tattgctgaa aaaccgggct tagtagctgg
    50521 ttttgtggca ggtgccattg cctcaaatgg tcttgctttt ggtaaggtac catttgcagc
    50581 aggaggagaa gtgagcttgg gcttaacggg cgtgccatca ggtttccttg gggcgcttgt
    50641 gggtggtttc cttgccggtg gtgttattct tgcccttcgt aaattgttgg caggcctacc
    50701 acgttctcta gaaggggtta aatctatcct cctttaccca ttacttggcg tccttgtcac
    50761 tggtttcttg atgctttttg tcaatattcc aatggcagct attaatacag cccttaatga
    50821 tttcttacaa ggtctttcag gaagctctgc tgtccttatg ggacttcttg ttggtggaat
    50881 gatggctgtt gacatgggtg gtcctgttaa taaggcagct tatgtttttg gtacaggaac
    50941 tttagcagct actgtggcaa atggtggttc ggtcgttatg gccgctgtta tggcaggtgg
    51001 tatggtacct cctcttgctg tttttgtagc cactctcttg tttaaagata aatttaccaa
    51061 agaagaacgt gaatcaggct tgacaaatat tgttatggga ctttcattca tcaccgaagg
    51121 agcaattccg tttggtgcag ctgacccagc acgtgcgatt cctagcttta tcgcaggttc
    51181 tgccttgaca ggagctcttg ttggtttggc tggtattaaa ttaatggcgc cacatggtgg
    51241 tatcttcgta atcgctttaa caagcaatcc aatcttatat cttgtctttg ttgtgattgg
    51301 cgcccttgta tcaggtatct tatttggcgc tcttcgcaaa aaagcctaaa aggtaaagaa
    51361 cttttttctt actaaaacta gaatctgtca aggttctagt tttttgctat actagagtta
    51421 aaggataaga aacgaggacc tttgaaggtg aaaaaaagga gaagaagggc tagatcatca
    51481 gtaaatcgac ttgtcttagg gttagtatta cttaatctga ttgttagtat gtggacacta
    51541 aaattgggaa accagcgatt agctccgtat gcggatcacg aaactctgac atttgtcagg
    51601 aagattagtc atgctgctca atcagtcgct caaaagaaac agttatacag ttcggtgatg
    51661 atggctcagg ccattttaga atccaataat ggcaagtcac aactaagtca aaaaccttat
    51721 tataattttt tcgggattaa ggggagctat aaagaacggt cagtcatttt tccaacttta
    51781 gaagacgatg gacaagggaa tctttatcaa attgatgctg cttttcgttc ctatgggagc
    51841 ctgacagctt gttttttaga ttacgcaaga gttttgaatg atccacttta tgacaaaacc
    51901 cacaaaaagt tttggtctca ttatcaagat gctactgcaa ccttaacagg cacttacgcc
    51961 actgatacaa cttaccatac caaattaaat gaattgattg aatggtatca actcactaat
    52021 tttgatggtc taatgaaata gttatccaca attttaaaaa aaatcagaag aaatatgtcg
    52081 atttcaagac aaaagttatc aatctcatta aattatctgt ggaaaagtta atttaaacgt
    52141 tcgtgtgcta taatagaaac atagaaaatg tataaaaaag gatatgtgaa taatgacaaa
    52201 aaagaaaggt aagcttgtac ttatcagtct ttttgttcta gcagcttgtt taggagctta
    52261 tagtgcaatg agacaatctc ataaaacttc aaacgtgtca gctgagacta tcgccagttc
    52321 ttcaacccga cattttattg atgaaattgg tccaactgct agtactattg gtcaagaacg
    52381 tgatctttat gcgtctgtta tgatagcaca agcgatttta gaatcaagta atggtaaatc
    52441 aagtctaagt caagcaccct atcataactt ctttggcatc aaaggggcct ataacggttc
    52501 ttctgtgacg atgtcaactt gggaagatga tggtaatggc aatacctata cgattgatca
    52561 agcctttaga gcttatccaa gtattgcaga ctcccttaat gactatgcag acttgctaag
    52621 ttctagcact tatataggtg ctagaaaatc aaacacgcta tcgtatcaag atgctacagc
    52681 agctctaact ggcttatacg ctacagacac cagttataac ttaaaactaa ataatattat
    52741 tgcaacctat ggtttgacgg cttatgatgt tgctaatagc tcagctcaag aaactggtct
    52801 agcaacttcg ggttatgttt ggaatgagta tcgtcgtaat tacactgatg cggagaccct
    52861 agcagttgat gaggcttggg ctaaacgcat gacttattaa tgtaacacta acaacaatct
    52921 gcttgcactg accccaaaaa agctggatac tctattttaa gtaaaggatt tagttctgta
    52981 ttgtacagaa ctaaatcctt ttagttttac tttgatatgt ttatcgttgt aataatcaat
    53041 gtcatttgta atcgcttgtt ctaagtcttc tagtgattta tagttattct cataaccata
    53101 gaacatttct gactttaaga tgccaaagaa agattccatc atgctattgt taggactgtt
    53161 tcttttacgt gacatagacg gacgaattcc tttagagttt aggaaatgat gataatagtt
    53221 gtgttgatat tgccaacctt gatcactcta tcatatagtt ccatcatagc atttatttgg
    53281 agatgtcttt ttccattatt ggtttaatgt gatttaagca aggttattag ctaaacttaa
    53341 tgccagacaa aaacacccca attattagat tttttgtcta acttttgggg cgcaattcaa
    53401 tctgagcagt tttagatttg gtatcaatgt tattataggt caattgatca tatttatcca
    53461 aagcttttag cttatttagt ccaaagataa atatcaaaat ggctgaaatc tttcatgttt
    53521 atagtcttat tgtctttata ttttttaaag acatcagatc tggtgctatt gggttttgcg
    53581 tcatataaat tgattttttc atgtttccta tttttactgt gaatttctaa actccccctt
    53641 atataaggag acttagtcaa ataaatttct tttgattcca tcaaaaattt tcttatttta
    53701 aaatcgaact cttgaatcgt aacaatatcc ttatcgattt ttataggatt tattaatgtt
    53761 ttttgctgtt gcccatctat gaaaaaattc cctgcaatag tattagtcct tagaatacca
    53821 tcatctgttg aaggtgtgat tccaccataa atatcatttt tattataggg agaaaatata
    53881 taaggcaggc caaacacatt gactttttga ccttttctaa atttttcagt gacaccacca
    53941 tctacttctg aatctacata aaaacatttt gattgataac cagatgtagc cacactaaaa
    54001 ttgtgagtag ttaaataact aatattgcaa ttactataat cagaaggagt aattgtgtat
    54061 atatatcgta actgatgttt tatttcatca atattactat ttttcgactc aacgagcttt
    54121 tctgttttaa atgtataaat aaacatcaga aaaaaaacta gtatactttt aatgattaat
    54181 cttttcaaat taccacctgt tcctctcctt attctttctc gttattataa gatgtaacct
    54241 aagtgaaaga acggaata
//
LOCUS       DATTYN010000011        52862 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.11, whole genome shotgun sequence.
ACCESSION   DATTYN010000011 DATTYN010000000
VERSION     DATTYN010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52862
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.11"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(<1..221)
                     /locus_tag="VB649_000818"
     CDS             complement(<1..221)
                     /locus_tag="VB649_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP1669782.1"
                     /translation="MAFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIR
                     LLETIPNSGDGFPLKITINKELTGFKLAIT"
     gene            complement(211..1338)
                     /locus_tag="VB649_000819"
     CDS             complement(211..1338)
                     /locus_tag="VB649_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP1669783.1"
                     /translation="MTYFDNAATTPLSPNVIRAMTAAMQDNFGNPSSIHFYGRRANKI
                     LRECRQAIARNLGASEQQIIVTSGGTESNNMAIKGYALAHQAKGKHLITTTIEHHSVL
                     HTMAYLEERFGFEVTYLPCQNGQINLSDLKQALRDDTILVSIMYANNETGDLLPIKDI
                     GNLLKDHQAAFHVDAVQAVGKLKIIPSELGIDFLSASAHKFHGPKGCGFLYSNGQPID
                     PLLHGGDQEGKRRASTENMLGIIGMAQALTDAMTCLDQSTDHIISLRHHLISLLEGLP
                     YYINQGTHYLPHVLNIGFLGYQNTILLTQLDLAGIAVSTGSACTAGAVNPSHVLAAYY
                     GDDSSRLKESIRISFSDQNSIEDVNQLAQTLKNILGGTDGF"
     gene            complement(1335..2315)
                     /locus_tag="VB649_000820"
     CDS             complement(1335..2315)
                     /locus_tag="VB649_000820"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEP1669784.1"
                     /translation="MTERYADKQIKLFSLTSNLPIAEKIAKAAGIPLGKMSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKPREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAER
                     YSKLGLSGSDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREQGYIIGDVSG
                     KKAILIDDILNTGKTFAEAAKILERSGATDTYAVASHGLFAGGAADVLETAPIKEIIV
                     TDSVKTKNRVPENVTYLSASDLIAEAIIRIHERRPLSPLFSYQPKGKNNA"
     gene            complement(2455..3033)
                     /locus_tag="VB649_000821"
     CDS             complement(2455..3033)
                     /locus_tag="VB649_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEP1669785.1"
                     /translation="MTNLEIEYKTLLTKNEYNRLLSQMKHVTPVTQTNYYIDTKAFDL
                     KANKMSLRIRTFANSAELTLKVPEKVGNREYNVPLFLEQAKDMIKHGNLPESTALDII
                     ISKGIKPSALVTFGNLTTVRRETVIPIGKLALDYNLYANTKDYELELEVSDALQGKID
                     FDSFLSEHHIAFKYAKSKVARCINTLKKFNDK"
     gene            3121..3792
                     /locus_tag="VB649_000822"
     CDS             3121..3792
                     /locus_tag="VB649_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEP1669786.1"
                     /translation="MTLDWEEFLDPYIQTVGELKIKLRGIRKQYRKQNRYSPIEFVTG
                     RVKSIESIKGKMILRGVIEENIAQDIQDIAGLRIMVQFVDDVEEVLALLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRNLSDGVGNSDDT
                     DELYR"
     gene            3767..4603
                     /locus_tag="VB649_000823"
     CDS             3767..4603
                     /locus_tag="VB649_000823"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEP1669787.1"
                     /translation="MTQMNYTGKVKRVAIIANGKYQSKRVASKLFSVFKDDPDFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDKVRFVGIHTGHLGFYTDYRDFEVDKLIDNLR
                     KDKGEQISYPILKVAITLDDGRVVKARALNEATVKRIEKTMVADVIINHVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSIIIPKKDKIE
                     LVPKRLGIYTISIDNKTYQLKNVTKVEYFIDDEKIHFVSSPSHTSFWERVKDAFIGEI
                     DS"
     gene            4600..5505
                     /locus_tag="VB649_000824"
     CDS             4600..5505
                     /locus_tag="VB649_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEP1669788.1"
                     /translation="MRFEFVADKRIKVKTLLKSHDVSKGLLAKIKYKGGNILVNGIEQ
                     NAIYLLQVGDVVTIDIPNEEPFEKLEAIPFDLDIVHEDDHFLVINKPIGFASIPSAIH
                     SNTIANFIKAYYVDNHYLDQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQTRSIE
                     KRYFALVSGNGTLPDEGDIIAPIGRSKDSIITRAVDPMGKYAKTSYKVVARYSENVHL
                     VDIKLHTGRTHQIRVHFAHIGFPLLGDDLYGGRLDLGITRQALHCHYLNFKDPFTESD
                     CSYAIHLTDDFDSVIIGLQKKDRGY"
     gene            5509..6504
                     /gene="pta"
                     /locus_tag="VB649_000825"
     CDS             5509..6504
                     /gene="pta"
                     /locus_tag="VB649_000825"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEP1669789.1"
                     /translation="MSIRSLFGGLREKILGKNMKIVFPEGNDERVVRAAARLKFEGLL
                     EPIILGQSEEVRNLLTKLGFADQDYTIINPNEYADFDKMKEAFVDIRKGKATLEDADK
                     MLRDVNYFGVMLVKMGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTSERYVFADCAINIDPTAQELAEIAVNTAETAKIFDIDPKIAMLSFSTKGSGKAPQV
                     DKVREATEIAKGLNPDLALDGELQFDAAFVPETAAIKAPDSAVAGQANTFIFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQAIESQG"
     gene            6631..7386
                     /locus_tag="VB649_000826"
     CDS             6631..7386
                     /locus_tag="VB649_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEP1669790.1"
                     /translation="MGNIALVTGASAGFGRAIVEHLIADGIKVIGASRRLEKLKALET
                     SFGSDNFYPLQMDVTDTKAIDDALTSLPNQWQDITILVNNAGLALGLDKAYEADFENW
                     MTMINTNIVGLIYLTRQLLPHMVSKDDGIIINLGSTAGTIPYPGTNIYGASKAFVKQF
                     SLNLRADLAGSHIRVTNIEPGLCEGTEFSKVRFNGDEARVKAIYQGAHAIQPQDIAST
                     VSWVIHQPPHVNVNRIELMPVSQSYGPQPVSRD"
     gene            complement(7580..8269)
                     /locus_tag="VB649_000827"
     CDS             complement(7580..8269)
                     /locus_tag="VB649_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEP1669791.1"
                     /translation="MKNAISILALLTPENQLEETFIRELSHHFSHLFEVTILTSKANI
                     ESNQLSTFQGIFSFHEHDIDLPTLYFKTSQHGQGFLVTESVFDQATAVLSLSQYLTGF
                     YQKFDGHFLQYLPLQARLSDANGNIIVDNHAFNGSFLPTTDKEIEDWILAELRLSDNP
                     CKTFLLPSGSLDHIYMQHYQALKNPQGQLVGVLDTVQDIKPLLNQYLEETGQAIVGWS
                     DVTSGPSILDH"
     gene            8689..9417
                     /locus_tag="VB649_000828"
     CDS             8689..9417
                     /locus_tag="VB649_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669792.1"
                     /translation="MIRFNNVSKTFGQTKVLQEQTFQINDREFFVLVGPSGSGKTTLL
                     KMINCLIEPSSGDILLNNVPQKELDLREMRLSIGYVLQQIALFPNLTVAENIAIIPEM
                     KQWSAEEIRQKTEELLDKVGLPAKDYLDRYPSDLSGGEQQRIGIVRAIISHPKILLMD
                     EPFSALDPISRKQLQELMLSLHKEFDMTIVFVTHDIDEAIKLGDRVAILNEGEIVQLD
                     RPEMIKTHPANAFVANLFGGDEHA"
     gene            9410..10936
                     /locus_tag="VB649_000829"
     CDS             9410..10936
                     /locus_tag="VB649_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEP1669793.1"
                     /translation="MPSLFVTFQNRFNEWLAALGEHLQISLLSLMIALLIGVPLAALL
                     SRSKRWSDIMLQVTGVFQTIPSLALLGLFIPLMGIGTLPAVTALVIYAIFPILQNTIT
                     GLNGIDPSLVEAGIAFGMTKWERLKTFEIPIAMPVIMSGVRTSAVMIIGTATLASLIG
                     AGGLGSFILLGIDRNNANLILIGAISSALLAIIFNSLLQYLEKASLRRIMISFGITLL
                     ALLASYTPMALSQFSKGKDTVVIAGKLGAEPDILINLYKELIEDQSDISVELKSNFGK
                     TSFLYEALKSGDIDIYPEFTGTITSSLLRDKPPLSNDPKQVYEDAKKGIAKQDKLTLL
                     KPFAYQNTYAVAMPEKLAKEYQIETISDLKAHADTLKAGFTLEFKDRADGYKGMQSQY
                     GLQLSVATMEPALRYQAIQSGDIQVTDAYSTDAEITKYHLKVLKDDKQLFPPYQGAPL
                     MKTSLLTKHPELKGILNQLAGKITEKEMQDMNYEVSVKGADANKIARDYLLKTGLIQK
                     "
     gene            11214..12197
                     /gene="guaC"
                     /locus_tag="VB649_000830"
     CDS             11214..12197
                     /gene="guaC"
                     /locus_tag="VB649_000830"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEP1669794.1"
                     /translation="MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVI
                     PANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMREQGLIASISVGVKACEY
                     EFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI"
     regulatory      12320..12415
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12502..13083
                     /locus_tag="VB649_000831"
     CDS             12502..13083
                     /locus_tag="VB649_000831"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEP1669795.1"
                     /translation="MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQ
                     KYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQD
                     GRRLIEDMGIEVTSLARIKNFENGNLNFLEADA"
     gene            13083..14366
                     /locus_tag="VB649_000832"
     CDS             13083..14366
                     /locus_tag="VB649_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEP1669796.1"
                     /translation="MTHSTKQEHSHSQSAVLGLQHVLSMYAGSILVPIMIAGALGYSA
                     RELTYLISTDIFMCGVATFLQLKLTKHTGVGLPVVLGCAFQSVAPLSIIGAQQGSGAM
                     FGALIASGIYVILVAGIFSKIARFFPPIVTGSVITVIGLSLVGVAMGNMGDNVKEPTA
                     QSMMLSLLTIVIILLVQKFTKGFVKSISILIGLVAGTLVSAMMGLVDTTPVVEASWIH
                     VPTPFYFGMPTFEITSIVMMCIIATVSMVESTGVYLALSDLTNDQLDEKRLRNGYRSE
                     GIAVFLGGLFNTFPYTGFSQNVGLVQISGIKTRRPIYYAAGILVVIGLLPKFGAMAQM
                     IPSPVLGGAMLVLFGMVALQGMQMLNRVDFQKNEYNFIIAAVSISAGLGFNGTNLFAS
                     LPETAQMFLTNGIVIATLTSVVLNLVLNGKDKQDE"
     gene            complement(14430..15368)
                     /locus_tag="VB649_000833"
     CDS             complement(14430..15368)
                     /locus_tag="VB649_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEP1669797.1"
                     /translation="MFVTQQLKLMGTVIDIQIESDKACQQLSRVIDLLYTYKNRFSAN
                     DSNSELMAINQAAGVKPVSVHSDLFNLIQIGKAHSLSTPSNLNIVIGPLVQAWRIGFE
                     DARVPNHNLISQQLALTDPRQVLIDDKKQTVFLQQVGMALDLGALAKGYITDKIMAYL
                     IEDGIDSALINLGGNVRVHGPNPKSPDKTFRIGIQKPDAKRGQHLGVIKVNNHSVVTS
                     GIYERQFTAKGKQYHHILDRQTGYPIETDMLSLTVMASSSFYCDIWATRLFGLDSSMI
                     ITLLNTFDNIEGLLVTRKHHVLMSNGLRHYFQPYYH"
     gene            complement(15421..15606)
                     /locus_tag="VB649_000834"
     CDS             complement(15421..15606)
                     /locus_tag="VB649_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEP1669798.1"
                     /translation="MPFVTIDLFEGRSQEQKNQLAREVTEVVSRIAKAPKENIHVFIN
                     DMPEGTYYPQGEMKQKS"
     gene            15744..16313
                     /locus_tag="VB649_000835"
     CDS             15744..16313
                     /locus_tag="VB649_000835"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEP1669799.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
                     PVYEGDQIQIGGNETYIPVCRKHYFNPDI"
     gene            16348..17427
                     /gene="prfA"
                     /locus_tag="VB649_000836"
     CDS             16348..17427
                     /gene="prfA"
                     /locus_tag="VB649_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEP1669800.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTR
                     ETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVIDALVMYDQTKKLESLNN"
     gene            17427..18266
                     /gene="prmC"
                     /locus_tag="VB649_000837"
     CDS             17427..18266
                     /gene="prmC"
                     /locus_tag="VB649_000837"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEP1669801.1"
                     /translation="MNYATLIRTYEDKLEQIDEDRENLAYVFREIKEWSSLDMLIHQN
                     QAVTPEDAVLLEHIFCSLSQHLSPQYITGNAYFRDLKLAVDKRVLIPRPETEELVDMI
                     LAENLDAPLNVLDIGTGSGAIAISLKKERPNWQVTASDISRAALDLAKANADAYQLDI
                     TFIESDVFSLISGTFDIIVSNPPYISYEDKEEVSLNVLQSEPHLALFAKENGYAIYRK
                     IIEQADNYLAKEGKLYFEIGYKQAEGIKDMLQAYFPQRHIRVVTDIFGKERMVVVDYG
                     VSS"
     gene            18250..18840
                     /locus_tag="VB649_000838"
     CDS             18250..18840
                     /locus_tag="VB649_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEP1669802.1"
                     /translation="MEYLASIIESGDALVLPTETVYGLFAKALDEKAVNAVYDLKQRP
                     RDKAMNLNVADFNSILAFSKEQPRYLKKLYQAFLPGPLTIILKANDQVPYWINSGLST
                     VGFRLPSHPITAALIQKTGPLIGPSANLSGKASGRVFDHIMQDFDFQVFGYADDPFLT
                     GKDSTILDLSGERAVILRQGAVTKEELLANVPELRF"
     gene            18858..19310
                     /locus_tag="VB649_000839"
     CDS             18858..19310
                     /locus_tag="VB649_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP1669803.1"
                     /translation="MLRPLSKTDCPMLQEINAKALGYLVSLDLLERQYERLIEDCHHY
                     FLAYADKDTNQLLGYVHAERYETLYASDGLNLLGLAVLPAYQRRGIGSALLRALESQA
                     RQEGIAFIRLNSASHRKEAHAFYRNLDYADDKTQLRFIKNLQGDDNDF"
     gene            19300..20556
                     /locus_tag="VB649_000840"
     CDS             19300..20556
                     /locus_tag="VB649_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEP1669804.1"
                     /translation="MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAIM
                     AAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQAN
                     AAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAIL
                     EQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPV
                     SYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQ
                     NLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIAHLIIKALVN
                     HDQETILEEVRQEVRQLTDAFPLYKK"
     gene            20563..21540
                     /locus_tag="VB649_000841"
     CDS             20563..21540
                     /locus_tag="VB649_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEP1669805.1"
                     /translation="MLDSYIKRIVIHQFSPNDTELLLSDRLVSITPRIDEYFRKKLAK
                     VFSDEAKRGQFEANNTFFTTIGDDLLETSVTIAQLWKEAFVISEDQKTNDLVFVQFDK
                     DGEPFFAFLRIALKEQFAHLSDNYEHPFTVTQNNLPSPTQTPDEALVINLKSGQYYLI
                     EKRVKHNGSFANYFSEHLLKVTPEQSVKKSIKMIEQTAQKIAEHFNQDDFTFQSKMKS
                     TLFKQLEADDVLSPEKLADQLFDDNLTARLTFVDQVKEVIPEPIKISDIDHSRQIKKL
                     ENQKLSLSNGIELTVPNAIYQDAEAVEFLLNDDGTYSILIKNIEDIKTK"
     gene            21541..22140
                     /locus_tag="VB649_000842"
     CDS             21541..22140
                     /locus_tag="VB649_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEP1669806.1"
                     /translation="MFRLLKRACSFLLLFVIYQSFVIHHNVQRVLAYKPMVEKTLAEN
                     DTKANVDLVLAMIYTETKGGEADVMQSSESSSGQKNSITDSQASIEHGVNLLSHNLAL
                     AEEAGVDSWTAVQAYNFGTAYIDYIAKHGGQNTVDLATTYSKTVVAPSLGNTSGQTYF
                     YYHPLALISGGKLYKNGGNIYYSREVHFNLYLIELMSLF"
     gene            22150..23874
                     /locus_tag="VB649_000843"
                     /pseudo
     CDS             22150..23874
                     /locus_tag="VB649_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635464.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            23871..25598
                     /locus_tag="VB649_000844"
     CDS             23871..25598
                     /locus_tag="VB649_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669807.1"
                     /translation="MIKTDHHLLKRVLQDLLKKPLPVCILVIASFVQVGLSVYLPVFI
                     GKAVDMSLSVNSWQTLKWLLGQMLVIIVVNTLIQWVMPLVYSRLLYQYSQQLKDKLLE
                     KIHRLPFAYLDRQTIGDLVSRVITDTEQLINGLQMVFNQFILGLLTILCTIIAMAQID
                     WLMLILVLVLTPSSLFLARFIAQKSFHYAQAQTKSRGNLAQFTEEILRQEGLVQLFNA
                     QEQSICDYHVLNKTYCETSQKAIFYASTVNPATRFINSVIYALLAGLGAFRIMAGLFS
                     VGQLTTFLNVVVQYTKPFNDISSILAEIQSSLACAQRLYDLLDIEIKEQEHFLTFKAS
                     AVKGQIDFEEVSFSYQKDRPLLKDINFSVSAGSKVAIVGPTGAGKSTLINLLMRFYEL
                     DAGSIKLDKVPIKCYAKEELRSITGMVLQETWLKDATVHELIAYGSEEASRDEVVAAA
                     KAAHAHFFIMQLPKTYDTYLSASDDALSQGQLQLLAIARMFLKKPKVLILDEATSSID
                     IRTEAVIQEALKELMRGRTSFIIAHRLSTIQSADLILVMDQGRLVEWGTHASLMSKNG
                     CYARLQKIE"
     gene            25837..27207
                     /locus_tag="VB649_000845"
     CDS             25837..27207
                     /locus_tag="VB649_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEP1669808.1"
                     /translation="MSKIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQIAGPEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE
                     TYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTTLGNGKIELFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNSTRDTNYIALASNAVRTGIVAAHNACGTDLEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKRLGFDAAVTEYTDNQKPEFIEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDMSMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAKD"
     gene            complement(27366..28349)
                     /locus_tag="VB649_000846"
     CDS             complement(27366..28349)
                     /locus_tag="VB649_000846"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEP1669809.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN"
     gene            28540..31017
                     /gene="gyrA"
                     /locus_tag="VB649_000847"
     CDS             28540..31017
                     /gene="gyrA"
                     /locus_tag="VB649_000847"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEP1669810.1"
                     /translation="MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTG
                     ALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVR
                     LAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAI
                     ENGVPKILSLRQIIDNYISHQKEVIIRRTRFDKDKAEARAHILEGLLIALDYLDEVIA
                     IIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLS
                     NKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTE
                     VSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRS
                     ATGVRGVKLREDDRVVGASRIQDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTAN
                     ITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKI
                     VTFTLVQPEDSSIDEINTDRENSISKK"
     gene            31047..31796
                     /locus_tag="VB649_000848"
     CDS             31047..31796
                     /locus_tag="VB649_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEP1669811.1"
                     /translation="MVKKQKRRKIKSMSWARKLLIAVLLILGLALLFNKPIRNTLIAR
                     NSNKYQVTKVSKKQIKKNKEAKSTFDFQAVEPVSTESVLQAQMAAQQLPVIGGIAIPE
                     LGINLPIFKGLGNTELIYGAGTMKEEQVMGGENNYSLASHHIFGITGSSQMLFSPLER
                     AQNGMSIYLTDKEKIYEYIIKDVFTVAPERVDVIDDTAGLKEVTLVTCTDIEATERII
                     VKGELKTEYDFDKAPADVLKAFNHSYNQVST"
     gene            31879..32292
                     /locus_tag="VB649_000849"
     CDS             31879..32292
                     /locus_tag="VB649_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP1669812.1"
                     /translation="MKLNAIHHVAIIVSDYNLSKNFYVNKLGFEIIRENYRPDKHDYK
                     LDLSCGRIELEIFGKVTSDPYYQAPPKRVSQPEFKSEACGLRHLAFRVTNIESYVDDL
                     KSLGILVEPIRHDDYTGEKMTFFFDPDGLPLELHE"
     gene            32907..33347
                     /locus_tag="VB649_000850"
     CDS             32907..33347
                     /locus_tag="VB649_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669813.1"
                     /translation="MTKKNHGVFWGLLLGSAAASIAYLSLSSSKKDQLLKDSAKKIDD
                     LNAYLQDKSKQVLDAVSEKVQESKDAVEVYGGIAAETVEEKWQDTKDAVEVYGGIAAE
                     TVEESLGQAKEKVEGIGEATSQTIQSKMEKLTSDKTDADDDDEK"
     gene            complement(33397..34308)
                     /locus_tag="VB649_000851"
     CDS             complement(33397..34308)
                     /locus_tag="VB649_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEP1669814.1"
                     /translation="MKTVRIFYNPNSGKKEDQLAGQVKDYFCQHGFSEDSVEVITPKD
                     ADQAFQLAKQAAKDKIDLVIPLGGDGTLNKIIGGIYEGGAHCLIGLVPSGTVNNFAKA
                     MHIPLQITEALDTILTGQIMQVDICKANQQYMISSLTLGLLADIAADVTAEEKRRFGP
                     LAFLKDSIRILKRNRSYAISLISHNHRIHLKTKFLLITMTNTIAGFPSFSPGAQADDG
                     YFQVYTMKKVSFFKFLWHINDFKQGDFSKAEEISHFQANTLSLLPQAKKQAILPRTRI
                     DGDKSDYLPIQLDIIPKAISIIVPTED"
     gene            complement(34425..35075)
                     /locus_tag="VB649_000852"
     CDS             complement(34425..35075)
                     /locus_tag="VB649_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEP1669815.1"
                     /translation="MNQTFKQSLPLSFSEEVANSVTHAIGAFAMLILLPISASYAYQT
                     YDLKAAIGISIFVISLFLMFLSSTIYHSMAYGSVHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVSGWLGYIIIVLQWGITLFGILYKIFAKRINEKFSLMLYIVMGWLVVFILPVII
                     QKTSLAFGLLMLFGGLSYTIGAVFYAKKRPYFHMIWHLFILLASALQFIAITFFML"
     gene            complement(35072..35512)
                     /locus_tag="VB649_000853"
     CDS             complement(35072..35512)
                     /locus_tag="VB649_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEP1669816.1"
                     /translation="MIFPSLPYWKDLPDLDLYLDQVLLYVNQCTDFSEVSDNKSLTAS
                     MINNYVKHGYVTKPIKKKYQKQQLARLIAISLFKTVFPIQDISRVLEELQAQADSESL
                     YNTFVTCWNQKAPIEEDIPPIVQVACQTVKDYHKTIYLSQEVTQ"
     gene            35731..36579
                     /gene="ylqF"
                     /locus_tag="VB649_000854"
     CDS             35731..36579
                     /gene="ylqF"
                     /locus_tag="VB649_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEP1669817.1"
                     /translation="MVMIQWFPGHMSKARRQVQENLKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKADLADATRTKEWKAYYESQGIKTLAINSKEQSTVKKVTEAAK
                     ELMADKIKRLRDRGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFREYY
                     PNRLTKRFKNIPLEEEAPEIIMTLTRQLGFKDDYDRFYTLFVKEVRDGKLGQYTLDQV
                     GDMDAD"
     gene            36569..37360
                     /locus_tag="VB649_000855"
     CDS             36569..37360
                     /locus_tag="VB649_000855"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEP1669818.1"
                     /translation="MPTSIKAIKESLEAVTSLLDPLFQELATDTRLGVQKALKSRQKA
                     IQAELAEEERLEAMLSYEKALYKKGYQAIAGIDEVGRGPLAGPVVAACVILPKYCKIK
                     GLNDSKKIPKAKHETIYQAVKEKALAIGIGIIDNQLIDEVNIYEATKLAMLEAIKQLE
                     GQLTQPDYLLIDAMTLDIAISQQSIIKGDANSLSIAAASIVAKVTRDQMMANYDRIFP
                     GYGFAKNAGYGTKEHLQGLKAYGITPIHRKSFEPVKSMCCDSTNP"
     gene            37425..38261
                     /gene="dprA"
                     /locus_tag="VB649_000856"
     CDS             37425..38261
                     /gene="dprA"
                     /locus_tag="VB649_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEP1669819.1"
                     /translation="MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGC
                     KHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYPMALKEIYNPPVLLFFQGNLDLL
                     EKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
                     AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGIL
                     VVEAKNRSGSLITCQIGIEEGRDIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILS
                     EY"
     gene            38369..40498
                     /gene="topA"
                     /locus_tag="VB649_000857"
     CDS             38369..40498
                     /gene="topA"
                     /locus_tag="VB649_000857"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEP1669820.1"
                     /translation="MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYL
                     GRSYKVVASVGHIRDLKKSSMSIDFDNNYEPQYINIRGKGSLINSLKKEAKAAKKVYL
                     ASDPDREGEAISWHLSHILGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQ
                     ARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDG
                     LFKKGTKKFQATFYGINGKKTKLDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLP
                     YTTSSLQQDAANKINFRTRKTMMVAQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQ
                     NDAAQFIINRFGANYSKHGNRVKNTSGAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKL
                     YTLIWNRFVASQMTAAVFDTVKVNLEQNGVLFVANGSQMKFDGYMAVYNDSDKNKMLP
                     EMAEGETVKKISTSPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTLEVIQRRYY
                     VKLSAKRFEPTELGEIVNKLIVEFFPDIVDVAFTAEMEGKLDQVEIGEEEWQHVIDQF
                     YQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGHPMVIKLGRFGKFYACSNFPECRNT
                     KAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQYPDCEFISWDLPIGRACPKSGDY
                     LIEKKVRGGKQVMCSNETCDYKEEKIK"
     gene            complement(40573..41457)
                     /locus_tag="VB649_000858"
                     /pseudo
     CDS             complement(40573..41457)
                     /locus_tag="VB649_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354842.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            41470..42015
                     /locus_tag="VB649_000859"
                     /pseudo
     CDS             41470..42015
                     /locus_tag="VB649_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631865.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            42030..43022
                     /locus_tag="VB649_000860"
     CDS             42030..43022
                     /locus_tag="VB649_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HEP1669821.1"
                     /translation="MKLKLYNVRGEEAVLAKKWADDNEIEISLTESPLTPETVKEAEG
                     FDGIANAQIGPLDDAIYPLLKEMGIKQIAQRSAGVDMYNLDLATENDIIITNVPSYSP
                     ESIAEFTVTIALNLIRHVELIRENVKKQNFTWRLPIRGRVLGDMTVAIIGTGRIGLAT
                     AKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADLVSLHMPPTAENTHLFNS
                     DLFKSFKKGAILMNMARGALIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQE
                     ITDALFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN"
     gene            43127..43792
                     /locus_tag="VB649_000861"
     CDS             43127..43792
                     /locus_tag="VB649_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HEP1669822.1"
                     /translation="MTYIALIGDIIQSKQLTDRSKVQKTLAAYLDDLNKTFAPYIISK
                     LSLTLGDEFQGLFQVDTPIFHLIDLINHHMDIPIRFGVGVGSILTDINPDISIGADGP
                     AYWHAREAIRYIHQKNDYGNTTLALRTGHHNQDDVLNSLLAAGDAIKANWRASQWEIF
                     DTLLDLGIYEEYFDQQRLGKQLSLSSSALSKRLKSSHVKIYLRTRQSALNCLKQIKEE
                     ADD"
     gene            43785..44501
                     /locus_tag="VB649_000862"
     CDS             43785..44501
                     /locus_tag="VB649_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEP1669823.1"
                     /translation="MINGVSHYLAQTPTLTLFLICHVLSDYQLQSQQVADLKEKHLTY
                     LGYHLIGVSIPLICLTLIIPQAWLMSLLVMISHALIDWLKPQVANSLKWKREWIFLLD
                     QCLHIAISSFAGLRLAGVTLPNWLPIPILMTVLFILLITKPTNIVFKLFFSKYQPDQG
                     EKMDTIIGAGATIGILERIVIGVCMIMGQFASIGLVFTAKSIARYNKISESPAFAEYY
                     LIGSLFSILSVFIAAWICFF"
     gene            44652..45998
                     /gene="trmFO"
                     /locus_tag="VB649_000863"
     CDS             44652..45998
                     /gene="trmFO"
                     /locus_tag="VB649_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEP1669824.1"
                     /translation="MSQSTATYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATP
                     QHKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEANRVPAGGAMAVDR
                     EGYAESVTAELENHPLIEVIRDEITEIPDDAITVIATGPLTSDALAEKIHALNGGDGF
                     YFYDAAAPIIDKSTIDMSKVYLKSRYDKGEAAYLNCPMTKEEFMAFHDALTNAEEAPL
                     NAFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQ
                     LRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLL
                     TETFQSRSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKREEALIFPQTTAIGS
                     LPHYVTHADSKHFQPMNVNFGIIKELEGPRIRDKKERYEAIASRALADLDTCLASL"
     gene            46151..47557
                     /locus_tag="VB649_000864"
     CDS             46151..47557
                     /locus_tag="VB649_000864"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase subunit B"
                     /protein_id="HEP1669825.1"
                     /translation="MIQFGGFSMQQQVAITETVLRDGHQSLMATRLSIEDMLPVLTIL
                     DKIGYYSLECWGGATFDACIRFLNEDPWERLRTLKKGLPNTHLQMLLRGQNLLGYRHY
                     ADDIVDKFISLSAQNGIDVFRIFDALNDPRNIQQALRAVKKTGKEAQLCIAYTTSPVH
                     TLNYYLSLVKELVEMGADSICIKDMAGILTPKAAKELVSGIKAMTNLPLIVHTHATSG
                     ISQMTYLAAVEAGADRIDTALSPFSEGTSQPATESMYLALKEAGYDITLDETLLEQAA
                     NHLRQVRQKYLADGILDPSLLFPDPRTLQYQVPGGMLSNMLSQLKQANAESKLEEVLA
                     EVPRVRKDLGYPPLVTPLSQMVGTQAAMNVILGKPYQMVSKEIKQYLAGDYGKTPAPV
                     NEDLKRSQIGSAPVTTNRPADQLSPEFEVLKAEVADLAQTDEDVLTYALFPSVAKPFL
                     TTKYQTDDVIKVTAFIKA"
     gene            47600..47914
                     /locus_tag="VB649_000865"
     CDS             47600..47914
                     /locus_tag="VB649_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669826.1"
                     /translation="MTYSFIDILQVTLVSLFLVLTCLTGIMGLMMLSGKLLSQEKKTL
                     SQQASSIPQEQEADKLSGEALETLLAKDELARIAVMTSLAYASQEESGKRFEVIAVER
                     KS"
     gene            47914..48264
                     /locus_tag="VB649_000866"
     CDS             47914..48264
                     /locus_tag="VB649_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin/lipoyl-binding protein"
                     /protein_id="HEP1669827.1"
                     /translation="MKRYEVTVNGQVYEVSLRELADGETVEVSQPAAPATEKEMNANA
                     AGGGIQVKAPMSGTILSIFATEGKAVKKGEAVLVLEAMKMENEILAPADGLVSKIHVV
                     ANQTVESEQVLISF"
     gene            48274..49404
                     /locus_tag="VB649_000867"
     CDS             48274..49404
                     /locus_tag="VB649_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEP1669828.1"
                     /translation="MLDVLNQMVQSSGLAHLTVNNLIMICLACFFLYLGIKKEYEPYL
                     MVPIAFGILLVNLPMAGLMDHPANGNPGGLLYYLYKGTSLGIYPPLIFLCLGASTDFG
                     PLIANPKTILLGGAAQVGIFLAFFLAIMLGMTPQEAASVGIIGGADGPTAIYVTTKLA
                     PDLLSTIALAAYSYMALVPIIQPPIIKLLTTKAERQVKMTQARTVSQKEKIIFPIMVT
                     IFVSLLVPSATTLVGCLMLGNLVREIKIVPKIVDNLQQVVMFCITIILGLTVGAKANG
                     DLFLSATTLKIIALGLIAFAAGTAGGVLMGKVMYYLSGNKVNPMIGAAGVSAVPMAAR
                     VVQKVGQEEDPSNFLLMHAMGPNVAGVIGSAIASGALLAFFG"
     gene            complement(49605..50489)
                     /gene="citG"
                     /locus_tag="VB649_000868"
     CDS             complement(49605..50489)
                     /gene="citG"
                     /locus_tag="VB649_000868"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEP1669829.1"
                     /translation="MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFM
                     TFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKG
                     LNFSMALLLGATGAYLARTPHLMTDLGCFSKEDTLAICRLVKPMTAHLIQTDLGHLNT
                     KKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYL
                     MSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGG
                     AADLLALTFYFAFLEKLL"
     gene            complement(50482..51177)
                     /locus_tag="VB649_000869"
     CDS             complement(50482..51177)
                     /locus_tag="VB649_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP1669830.1"
                     /translation="MNPIIEAVKQNLDLSRNIPLKIAFYNALKKTIILRQIPVGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIKDACEIFEIRKALET
                     LATVQAMHLMTEEDFKVMHNLLEDCETFIAEDDTNRILDNFNAFNNLIYSYSQMVRLK
                     EIVTELQAYLVYFRKISISSVERRKRALSEHWMIYRGMKNKDHEQITLITHEHLNSSL
                     EFILKEMRPEQND"
     gene            complement(51335..52738)
                     /locus_tag="VB649_000870"
     CDS             complement(51335..52738)
                     /locus_tag="VB649_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEP1669831.1"
                     /translation="MLLTMLAYAMIIVFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFNADAKFVAFVGDGGIAKDLTAIGPMVMYGINNTAKTGIMLLFAILFFSVMLDAG
                     LFDPITEKMIRFAKGDPMKVLIATAVVAAAVSLNGDGTTTTLICCSAFLPIYKKLDMK
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLGVGPEILGYLAPGMILSLLYVICWVAP
                     SMGRKERARLGVIDLSEEDMRQLTDITDPDTLFIRRPKNFVFNAILTIGLITWLVAGS
                     FNKSIAMAPLLLFAVGTCIALMVNYPVLKDQSKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALVSAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYALIIFVI
                     FVVTIIAMGQMPLYIPQ"
BASE COUNT        16561 a         9396 c        10813 g        16092 t
ORIGIN      
        1 gtgatagcta atttaaaacc tgtgagttct ttattaatag tgatttttaa agggaaacca
       61 tcccctgaat taggtattgt ttcgagtaaa cgtattaatt ggtagtgccc tactttagtt
      121 tgactaaatg tagtatctct tagggtatat tttttaatgt ttggactgat tgtataaagg
      181 tatttacagt ctttaagctt aatttctttt tcaaaagcca tctgttcctc ctaaaatatt
      241 ttttaatgtt tgagctaatt gattaacatc ttcaatgcta ttttgatctg aaaaactgat
      301 acgaattgat tcttttaaac gagaagagtc atccccatag tacgcagcta aaacatgact
      361 tggattaaca gctccagcag tacaagcaga accagttgat actgcaatgc ctgctaagtc
      421 aagttgtgtt agtaaaatag tattttggta gcctaaaaat ccaatattga gaacatgagg
      481 aagataatga gtaccttgat taatatagta gggtagtcct tctaggaggc taatcaagtg
      541 atgacgtaaa ctaataatgt gatcagttga ttggtcaaga caagtcatag catcagtcaa
      601 agcttgtgcc ataccaataa tacctaacat attttcagta cttgcgcgtc gctttccttc
      661 ttgatcaccc ccgtgaagaa gagggtcgat tggttgtccg ttactgtata aaaagccgca
      721 tcctttagga ccatgaaatt tgtgagcaga agcagataaa aagtcaatcc caagttcgct
      781 aggaataatc ttgagtttgc caacagcttg aacggcatca acatgaaaag cagcttgatg
      841 gtctttgagc agattcccaa tgtccttaat aggtaacagg tcacctgttt cgttattggc
      901 atacattatg cttaccaaaa tggtgtcatc tctcaaggct tgttttaagt cagataaatt
      961 tatttgtcca ttttgacaag gcaaataagt gacctcaaaa ccaaatcgct cttcgagata
     1021 ggccatggta tgaagcacag agtggtgctc aatagtagtt gtgatgagat gtttgccctt
     1081 tgcttgatga gctaaagcat agccttttat ggccatatta ttgctttcag ttccaccgga
     1141 cgttactata atttgctgtt cacttgcccc caagtttcta gcgatagctt gtcggcattc
     1201 acgaaggatt ttattggctc ggcgcccgta gaaatgaata ctagaggggt taccaaagtt
     1261 atcttgcata gctgctgtca tcgccctaat cacattagga ctaagtggtg tggtggcggc
     1321 gttatcaaag taagtcatgc gttatttttg cctttaggtt gataagaaaa aagcggactt
     1381 aagggtcttc tttcatggat acgaataata gcttctgcga ttaaatcact ggcgctaaga
     1441 taagtaacgt tttctggcac acgattttta gttttaacag aatctgtaac gataatttct
     1501 ttgattggag ctgtttctaa tacatcagca gctccaccag caaataagcc atggctagcg
     1561 accgcgtaag tatcagtagc gcctgagcgt tcaagaattt tagcagcttc tgcaaaggtt
     1621 ttcccagtat ttaaaatatc atcaattaaa atggcttttt taccagaaac atcaccaata
     1681 atataacctt gttcacgttc agaatcatct tgtgcatagt cgataatagc aatcggggaa
     1741 tcaagatatt cagccaagct tctagcacgt ttaattccag aatttttagg gctaacgaca
     1801 acaacatcag aacctgataa gcctaattta ctgtaacgtt ctgcaaaaag agggactgta
     1861 aagaggttat ccactggaat atcaaaaaaa ccttgtacct gaacagcatg taagtcaagc
     1921 gtcactacac gatcaatacc agctttagtc agcatattag ctactagttt agcagtaatc
     1981 ggttcgcggg gcttagcgac acggtcttga cgagagtaac caaagtatgg caatacaata
     2041 ttgacggtat tagcacttgc acgtttacaa gcatcaatca tgatgagtaa ttcccaaaga
     2101 ttatcattga caggaaaact agtggattga ataatataga tatcatctcc acgcactgtt
     2161 tcttcaatat tgatcataat ttctccatcg gaaaattgac gtgaagacat ttttccaaga
     2221 gggattccag cagctttagc aattttttca gcaattggaa gatttgatgt gagtgagaac
     2281 agtttgattt gcttgtcagc atatcgttca gtcatgatag atttagctcc ttaacttcaa
     2341 taaaattggg taaactattt tattaatgag tcacattacc caaaagtgtt taattgacat
     2401 ccctatttta acagaaaaac agaaaaattt cagtttttct gtcgctttta gccattattt
     2461 atcgttgaac ttttttaagg tgttaataca ccgagctact ttgcttttag catatttgaa
     2521 agcaatgtga tgttcagata aaaaagaatc aaaatcaatc tttccttgaa gagcgtcact
     2581 tacttctaat tctaattcat agtctttggt attggcatat aggttatagt ctaaggccaa
     2641 tttacctatc ggtatcactg tctcgcgacg aacggtagtt aaattgccaa aagttaccag
     2701 tgcagatggt ttgatacctt ttgaaataat aatatcaaga gcagttgatt caggaagatt
     2761 cccatgttta atcatatctt ttgcttgttc aagaaaaaga gggacattgt actcacgatt
     2821 ccccactttt tctggcactt ttaaggttaa ttcggcgcta tttgcaaatg ttcgaatacg
     2881 taatgacatt ttgttagctt ttaaatcaaa tgcttttgta tcaatatagt aattagtttg
     2941 tgtaacaggc gtcacatgtt tcatttgaga taaaagacgg ttatactcat tttttgtaag
     3001 tagagtttta tattcgattt ctaggttagt catgggaaat tccttttaat ttgtgctata
     3061 ataaattgtt atttcaattt tatattatta tcctggcttt gacaagaaag gagacaatag
     3121 atgaccttag attgggaaga atttttagat ccttatatcc aaacagttgg tgaattaaaa
     3181 ataaaactac ggggtattcg caagcaatat cgtaagcaaa atcgttattc tccgattgaa
     3241 tttgttacgg gacgtgttaa gtcaattgaa agtattaaag gaaaaatgat tttacgtggt
     3301 gttattgaag aaaatatcgc acaagatatt caagatattg ctggactacg tattatggtt
     3361 cagtttgttg atgatgtgga agaagtctta gctctattgc gtcaacgaca agacatgaca
     3421 attgtttatg aacgagatta tattcgcaat atgaagtcca gtggctacag gtcttatcat
     3481 gtggtggttg agtaccctgt tgacaccatt gaaggtcaaa aaaaggtctt agcggagatt
     3541 cagattcgta ctttggcaat gaacttttgg gcgaccattg agcattcttt aaattataaa
     3601 tatggtggag acttcccaga agaaattaaa aagcgacttg aagtgactgc taaaattgct
     3661 ttagaattag acgaagaaat gcgtaagatt cgagaagata ttcgggaggc tcaattattg
     3721 tttgaccccg tgacacgaaa tttaagtgat ggtgtaggaa atagtgatga cacagatgaa
     3781 ttatacaggt aaggtaaagc gagttgctat tattgcaaat ggtaagtacc aaagtaaacg
     3841 cgtcgcctcc aaacttttct ccgtatttaa agatgatcct gatttctatc tttcaaagaa
     3901 aaatccggat attgtgattt ctattggcgg agatgggatg ctcttatctg cctttcacat
     3961 gtatgaaaaa gaattagata aggtacgttt tgtaggaatc cacaccggtc atcttggctt
     4021 ttataccgat tatagggatt ttgaagttga taaattgatt gataatttaa gaaaagacaa
     4081 gggagaacaa atctcttatc ctattttaaa agttgctatt actttagatg atggtcgtgt
     4141 ggttaaagcg cgtgctttga atgaagcgac ggttaagcgt attgaaaaaa cgatggtagc
     4201 agatgttatt attaaccatg tcaaatttga aagcttccga ggtgatggga tttcagtatc
     4261 gaccccgaca gggagcacag cctacaataa atctttaggt ggtgctgtct tgcatccgac
     4321 gattgaagcg ctgcaattga cggaaatttc cagtcttaat aaccgtgtct ttagaacctt
     4381 gggctcatca atcattattc ccaaaaaaga taagattgag ttagtgccaa aacgattagg
     4441 aatttatacc atttccattg ataataaaac ctatcagtta aaaaatgtga cgaaggtgga
     4501 gtattttatc gacgatgaga aaattcattt tgtttcctct ccgagtcata cgagcttttg
     4561 ggaaagggtc aaggatgcct ttattggaga gattgactca tgagatttga atttgtagca
     4621 gacaaacgaa taaaagtaaa aaccctttta aaaagtcatg atgtctctaa aggactattg
     4681 gctaaaatca aatataaggg cggtaatata ttagtgaatg gtattgaaca aaatgccatt
     4741 tatttattgc aagtgggaga tgttgtcacc attgacattc caaacgaaga gccctttgaa
     4801 aagcttgaag ccatcccttt tgatttggat attgttcacg aggatgatca ttttttggtg
     4861 attaataaac ccattggctt tgccagtatt ccaagtgcca tccactccaa taccattgct
     4921 aactttatca aggcatatta tgtggacaat cattacctag accaacaagt gcatatcgtg
     4981 actcgtttag acagagatac gagtggcttg atgttatttg ctaagcatgg ttatgctcat
     5041 gcaaggttgg acaagcaact ccaaactcgc tcaatagaga aacgttattt tgctctggtt
     5101 tctggaaatg ggacgttgcc agatgaagga gatattattg ctccaattgg gcgttcaaaa
     5161 gatagtatta ttaccagggc agttgaccct atgggcaaat atgccaagac tagctataag
     5221 gttgtggcgc gctattcaga aaatgtgcat ttagtggata tcaaattgca tacaggacgt
     5281 acccatcaaa tcagagttca ttttgcccat attggttttc cacttttagg ggatgacctt
     5341 tacggaggtc gtttggactt aggaataaca aggcaagctt tacattgtca ttatttgaat
     5401 ttcaaagatc catttacaga aagtgattgt agctatgcaa tacacttgac agatgacttt
     5461 gatagcgtta tcataggttt acagaaaaaa gatagaggtt attaaagaat gagtattcgt
     5521 agtttattcg gtggtttaag agaaaaaatt cttggtaaaa acatgaagat tgttttccca
     5581 gaaggtaatg atgagcgcgt cgtccgtgca gctgctcgtt tgaaatttga aggactctta
     5641 gaaccgatta tccttggaca gtcagaagag gtacgcaacc ttttgacaaa attaggcttc
     5701 gctgatcaag actatactat cattaatcca aatgaatatg cggattttga caaaatgaaa
     5761 gaagcttttg ttgacatccg taaaggaaaa gcaacgcttg aagatgctga taaaatgctt
     5821 cgtgatgtga attactttgg tgttatgttg gttaaaatgg gattagcaga tggaatggta
     5881 tctggtgcta ttcattcaac agctgatact gttcgtccag cccttcaaat cattaaaacc
     5941 aaaccaggta tttcaagaac ttcaggtgtt ttcttgatga atcgcgaaaa tacgagtgag
     6001 cgttacgtgt ttgctgattg tgctatcaat attgacccaa cagcacaaga attggcagaa
     6061 atcgctgtta acacagctga aacagctaaa atctttgata ttgatcctaa aattgctatg
     6121 ttaagcttct caacaaaagg ttctggtaaa gcgcctcaag ttgataaggt aagagaagca
     6181 acagaaattg ctaaagggtt gaaccctgat ttggcacttg atggtgagtt gcaatttgat
     6241 gcagcctttg ttcctgaaac ggcagctatc aaagcaccag attcagcggt tgctggccaa
     6301 gccaatactt ttattttccc tgacttacaa tctggaaata ttggttacaa aattgcacaa
     6361 cgtttaggaa tgtttgatgc tattggacca atcttacaag gattgaacaa acctgttaat
     6421 gatttatctc gtggctcaag cgctgaagat atttacaaat tagctattat tacagcagca
     6481 caagctatcg aaagccaagg gtaacttaag accccttgat ataggattct aaccgctaag
     6541 tgatgtgtta gaagttatcc taagactaat tgacattatt aaaaacgagt tggccagacc
     6601 atctcgtttt ttttgaaggt gaggaaatgt atgggaaata ttgccttagt aacaggggct
     6661 tcagccggtt ttggcagagc cattgtcgaa cacttaattg cagatgggat aaaggttatt
     6721 ggtgcttctc gtcgtcttga gaaactcaag gccttagaaa cgagctttgg gtcggacaac
     6781 ttttaccctt tgcagatgga tgtcacagat accaaagcga ttgatgatgc tttgacaagt
     6841 ctaccaaatc agtggcaaga tattactatt ttagtgaata atgcaggctt ggcattggga
     6901 cttgataagg cttatgaagc cgattttgag aattggatga cgatgattaa cactaatatt
     6961 gttgggttga tttatctcac acgtcaatta ttaccacata tggtctccaa agatgatggt
     7021 attattatta atttagggtc aaccgcaggg acaattccct atccgggaac taatatttat
     7081 ggggctagca aggcttttgt taagcagttc tcactcaatt tacgagctga tttagcaggt
     7141 agccatatac gtgtgaccaa tattgaaccc ggtctatgtg aagggacaga attttcaaag
     7201 gttcgcttta atggtgatga ggcacgggtg aaggccattt atcaaggagc acatgccatt
     7261 caacctcaag atattgcgtc gactgtatca tgggtgattc atcagccccc tcatgttaat
     7321 gttaatcgta ttgagctgat gccagtgtcg caaagttatg gaccgcaacc agttagtcgt
     7381 gactagcaag ggatgagtcc ataagaataa taatctttag aaaaatggtt tactggtatg
     7441 gattattctt tataagtgag acttaccgat ttagtcatca aaaaaagcaa tcaagaagaa
     7501 ggttttgagg tcttcaagcg ttcatgattg cttcttgtgc gttgatgatt taggctgaac
     7561 tccctattta aaatcaagtt tagtgatcta aaatggaagg gcctgatgtg acatcggacc
     7621 agccaacaat ggcttgtcca gtttcttcta aatactggtt taataacggt ttaatgtctt
     7681 gaacggtatc caaaactccc accagctgac cttgaggatt tttaagagct tgataatgct
     7741 gcatgtaaat atgatccaat gaacccgaag gaagtaggaa ggttttacaa gggttatctg
     7801 ataaacgcaa ttcagcaaga atccaatctt ctatttcttt atcagtagtt ggcaaaaaac
     7861 ttccattaaa agcatgatta tcgactatga tgtttccatt tgcatcagat aaccttgctt
     7921 gcaaaggaag gtactgtaaa aaatgtccat caaatttttg gtaaaatcca gtgaggtatt
     7981 ggcttaacga taagactgct gttgcttgat caaagacact ttctgtcact aaaaagccct
     8041 gaccatgttg agaagttttg aaatagagtg taggcaagtc aatgtcatgc tcatggaaac
     8101 tgaaaattcc ttggaaagtc gacaattgat ttgactcaat gttggctttg ctagtgagaa
     8161 tagtcacctc aaaaaggtgt gagaagtggt gggaaagctc tctaataaac gtctcttcaa
     8221 gttggttttc aggtgttaag agcgctaaaa tggaaatggc atttttcata attgtatgat
     8281 agctgtattt tctagaaaag acaattaatc tgcttatcta tcatcatagg caagtctagg
     8341 atttttgata aggtaatttt ggagagatag gctgacccag tgacctgttt ttctataagg
     8401 gggtaatagt ctcattattt gacttatagt gggaaacttt ttataatggt caacaacaaa
     8461 cgacaagaaa ataatgagag aaaaagtttt tgagaattgg tagtttctac cttactgagg
     8521 atacctaaga gtccctttaa ttagtagatg cgtttgtcta aaaatggtag ggcatgcagt
     8581 gattccttgt agttactcag aacgttttga gaaaaaatga cagagagaca ggttgaatga
     8641 actcatcagc ttttatgctg ttactttaac caatgaattg gagaaataat gatacgtttt
     8701 aataatgttt ctaaaacttt tggtcagaca aaggttttgc aagagcagac ctttcaaatt
     8761 aatgaccgtg aattttttgt gctggttggt cccagcggat cggggaaaac cacactttta
     8821 aaaatgatta actgccttat tgaaccaagc tctggagata ttttactgaa taacgtccca
     8881 cagaaagagt tagatttacg tgagatgagg ctatctattg gatacgtgtt gcagcaaatt
     8941 gctcttttcc ccaatctcac agtagctgaa aatattgcga ttatccctga gatgaagcaa
     9001 tggtcagctg aagaaattag acaaaaaact gaagaattat tggataaggt gggcctacct
     9061 gctaaagatt atcttgatcg ttacccaagt gatttatcgg gaggtgaaca gcaacgtatt
     9121 ggtattgtac gtgctatcat ttctcatcct aaaattctat tgatggatga accattttca
     9181 gccttagatc ctatttcacg taaacaattg caagagttaa tgttgagtct tcacaaggaa
     9241 tttgacatga cgattgtatt tgtgacacat gatattgatg aggccattaa attaggagac
     9301 cgcgtagcta ttttaaatga gggagaaatt gtgcaactgg atcgcccaga aatgattaag
     9361 acccaccctg ctaatgcttt tgtggccaat ttatttggag gtgatgagca tgcctagttt
     9421 gtttgtaact ttccaaaacc gttttaatga atggctggcg gctctggggg aacacctgca
     9481 aatttccctt ttatctctta tgatcgcctt gctaataggt gtgcctttag cagcccttct
     9541 cagtcgcagc aaacgttggt cagacattat gttacaggta acaggtgttt ttcaaaccat
     9601 tccctcactg gctttgcttg gtcttttcat ccctttaatg ggaattggaa cgttgcctgc
     9661 agtgacagct ttagttatct atgcgatttt tccgatttta caaaacacca tcacaggatt
     9721 aaatggtatt gacccaagtc tcgtggaagc aggaatagct tttgggatga ccaaatggga
     9781 gcggttaaaa acgtttgaga ttccaattgc aatgcctgtt attatgtcag gtgtgcggac
     9841 gtcagcagtc atgattatcg gcacagctac tttagcttcc ttgataggag ccggtggact
     9901 tggctctttc atcttattgg ggattgatcg taataatgct aacctgattc tgataggggc
     9961 tatttcttca gctctgctag ctattatttt caatagtttg ttacagtacc ttgagaaagc
    10021 ttccttgcga cggattatga ttagttttgg aatcacctta cttgcattgc tagcatcgta
    10081 tactcctatg gcgcttagtc agttttcaaa aggaaaagat acagtggtta ttgccggtaa
    10141 attgggagca gagcccgata ttctgattaa tctctataag gaattaattg aagaccaatc
    10201 agatataagt gttgagttga aatctaattt tgggaaaact agcttcttat atgaagccct
    10261 taaatctgga gatattgata tctatcctga atttacagga accataacat caagtctttt
    10321 acgcgacaaa ccacctttgt ctaatgaccc taagcaggtc tatgaggatg ctaaaaaagg
    10381 cattgctaag caagataaac tgacccttct taagccattt gcttaccaaa atacgtatgc
    10441 tgttgctatg ccagaaaaat tggctaagga atatcagatt gaaactattt ctgatttaaa
    10501 agcgcatgct gatactttaa aggctggttt tactctggaa tttaaggaca gagcagatgg
    10561 ctataaggga atgcaatctc aatatggatt acagctatct gtggcgacta tggagccagc
    10621 tcttcgttat caagcaattc aatcaggaga tatccaagta acagatgctt actctacgga
    10681 tgctgaaatt acgaaatacc atttgaaagt tttaaaggat gataaacagt tgtttccacc
    10741 ttatcaggga gctcctttga tgaaaacttc cttattaaca aaacatccag aattaaaagg
    10801 tattcttaat caattagcgg ggaaaattac tgaaaaagag atgcaggaca tgaactacga
    10861 ggtatctgtt aaaggagcag atgctaataa gatcgctcga gattatctgt tgaaaacagg
    10921 cttaatccag aaataaacag aaatgttggt ccgtaggact ggcatttttt cgtctcttaa
    10981 gttcaagaag taacaattca taaatacaaa aaccgaacat ttaaattaaa aatagtattt
    11041 aaatttgaca aaatataaac aaataagtaa tctataaaat gaaaggtaag tttttaccta
    11101 aagatacctc taatcatcag aggtcatagg aaggtcattt tgtataaagg acgtggagaa
    11161 gaagatgaga actgacttat tttctttcat ctgtgtctaa agaggagaaa cttatgttta
    11221 atgacatccc tgtatttgat tatgaagata ttcaactgat tcctaacaag tgcattatta
    11281 ctagtcgttc acaagcagat acaagtgtga cactcggaaa ataccagttc aagctaccag
    11341 ttatcccagc aaatatgcaa accattattg atgaaacaat tgctgagcag ttggcaaaag
    11401 agggttattt ttatattatg catcgttttg atgaagatag ccgcaaacct tttatcaaac
    11461 gcatgcgtga acaaggcttg attgcatcaa tctctgttgg ggttaaagct tgtgaatatg
    11521 aatttgtgac ttctttgaaa gaggatgctc ctgagtttat caccattgat attgctcatg
    11581 gtcatgctaa cagtgttatt gatatgatta agcatatcaa aactgaatta ccagaaacat
    11641 ttgtcattgc tggaaatgtt ggtacgccag aagctgtacg agaactcgaa aatgcaggtg
    11701 ctgatgctac taaagtaggc atcggtccag gcaaagtatg tatcactaaa gttaaaaccg
    11761 gtttcggtac aggtggttgg cagctagcag cactgcgctg gtgcgcaaag gcagctcgta
    11821 agcctatcat tgctgatggt gggattcgca cacatggtga tattgctaaa tccatccgct
    11881 ttggagcgag tatggtcatg attggatcgc tttttgcagg acatattgaa agtcctggaa
    11941 aaacggtaga agtggatggt gaaacgttta aagaatatta tggctcggcg tcagaatatc
    12001 aaaaaggcga gcataaaaat gtagaaggca aaaaaatctt attgcctaca aaaggtcact
    12061 tatcagatac cctgaccgaa atgcaacagg atttgcaatc gtccatttct tacgcgggtg
    12121 gtaaagattt agacagtttg cgtcatgttg attatgttat tgtcaaaaat tccatttgga
    12181 atggtgattc catttaaatg atatggagtt agctaggacc agtaaagaat tttttagctt
    12241 aatgctggag atgcttttat catatctctg taggtattga aaaaaataag aaacatggta
    12301 aaatagtaaa ttatcataat gaattcaata atgacatact tatttatgct gtgaattggc
    12361 gcagcgtctc tacaagacac cttaatgtct aacaataagt aagcttttag gcttgcttgg
    12421 tttttaacct tgcaaagtga gaaactctta tagtttctca ctttgcggca ggctttttct
    12481 atttgaatca aaaggagatt tatgcagtta cttgaagaac gcatcttaac agatggcaat
    12541 attctaggag agaatattct aaaggtagat aattttttaa ctcatcaagt tgattaccgg
    12601 ttgatgaaag caattggtaa agtgtttgct caaaaatatg ctgaggctgg cattacaaaa
    12661 gtggttacaa tcgaagcttc aggtattgca ccagccgtat acgctgcaga agcaatggat
    12721 gttcctatga tttttgcgaa aaaacataaa aacattacca tgacagaagg cattttgaca
    12781 gcagaagttt attctttcac taaacaagtg acgagcacgg tgtctatcgc tggtaaattc
    12841 ctatctaaag aagacaaggt tttgattatt gatgactttt tagctaatgg tcaggcagcc
    12901 aaaggcttga ttgagattat tggtcaagca ggggcacaag tcgtcggcgt tggtattgtg
    12961 attgagaaat ctttccaaga tggtcgtcga ttgattgaag atatgggcat tgaagtgacc
    13021 tcattagccc gtattaaaaa ctttgaaaat ggtaatctaa acttcttgga ggctgacgca
    13081 taatgacaca ttcaacaaag caggaacatt ctcactcgca atcagctgtc cttggcttac
    13141 agcatgtgct ttcgatgtat gccggatcta ttttagtacc aattatgatc gcaggtgctt
    13201 taggttattc cgctagagag ttgacctacc tgatttcgac agatattttc atgtgtggtg
    13261 tggctacttt cttacagtta aagttaacca agcatacggg agtgggatta ccagttgttt
    13321 taggatgtgc ttttcaatca gtggcacctc tatccattat tggagcgcaa caaggttcag
    13381 gtgccatgtt tggagccctc attgcgtcag gaatttatgt cattttagtg gcaggtattt
    13441 tttctaagat tgctcgtttc ttcccaccaa ttgttacagg atcggtcatt accgttattg
    13501 gcttaagtct cgtaggtgtt gctatgggga atatgggaga taacgtcaaa gagcctacgg
    13561 cacaaagcat gatgttatca ttgttgacga ttgtcattat tcttttagtc caaaaattta
    13621 ccaaaggttt tgtgaaatcc atttccattt tgattgggct tgtagcggga actttggttt
    13681 cagccatgat gggattagta gatacaactc ctgttgtaga ggcttcttgg attcatgtgc
    13741 caaccccatt ttattttggc atgccaactt ttgaaatcac ttctattgtg atgatgtgta
    13801 tcatcgcaac ggtttctatg gttgaatcaa caggtgtcta cttagcgctt tcagatttga
    13861 ctaatgatca attagatgaa aaacgtttgc gcaatggtta tcgctcagaa gggatcgcag
    13921 tatttctcgg tgggttattt aataccttcc cttacactgg tttttctcaa aacgttggac
    13981 ttgtccaaat ctcaggtatt aaaacccgtc gtccgattta ctacgcagca ggtatccttg
    14041 tggtcattgg cctactccct aaatttggag caatggcaca aatgattcca agcccagttc
    14101 ttggtggagc tatgcttgtt ctctttggta tggttgctct tcaaggaatg caaatgctta
    14161 atcgtgttga tttccaaaag aacgagtata attttattat tgctgccgtt tccatctcag
    14221 caggtttagg ctttaatggc actaatcttt ttgccagctt accagagaca gctcaaatgt
    14281 tcttaacgaa tggtattgtg atcgcaacct tgacatctgt tgtcttaaat ttagttttaa
    14341 atggcaaaga taaacaagat gaataattaa aaaacggcta attgagccgt tttttctgtg
    14401 atcagttttg agcaaaccgt taaccccttt taatgatagt atggttgaaa atagtgtctc
    14461 aaaccatttg acataaggac atggtgcttt cttgttacta gaagaccttc aatattatca
    14521 aaggtgttta aaagtgtgat aatcattgag ctatcaagac caaataaacg ggtagcccat
    14581 atgtcacaat aaaaagaaga agaggccatg accgttaagc taagcatatc tgtttctata
    14641 ggatagcctg tctgacgatc taagatatga tgatactgtt tccctttggc tgtaaactgc
    14701 ctttcataaa ttccagaagt cacaacagag tgattgttaa ccttgatgac accaagatgt
    14761 tgcccacgtt tagcatctgg tttttgaatg ccaattcgaa aagtcttgtc agggcttttc
    14821 ggattaggtc catgaacgcg tacatttcca cctaaattaa taagggcaga gtcaatacca
    14881 tcttcaatca ggtaggccat aatcttatca gtaatataac cttttgctaa ggctcctaag
    14941 tctaaagcca ttcctacttg ttgtaaaaag acagtctgtt ttttgtcatc tataagaacc
    15001 tgtctaggat ctgttagagc taactgttgt gagataaggt tatgattagg cactctagca
    15061 tcttcaaatc caattcgcca ggcttgaaca agtggcccaa tgacgatatt aagattactt
    15121 ggtgttgaca agctatgagc tttaccaatt tggattaggt taaataaatc agagtggacg
    15181 ctgacgggtt taacaccagc cgcctgatta atagccatca attcagagtt tgaatcatta
    15241 gctgaaaaac gatttttgta agtatataat aagtcaatga ctctacttag ttgttggcaa
    15301 gctttgtcag attcgatctg aatatcaata actgttccca ttagctttaa ttgttgcgta
    15361 acaaacataa ttagttctct ttttagcaga atacccccac taaggagtgg gggaaggtca
    15421 ttatgatttt tgtttcattt caccttgagg atagtaagtt ccttcaggca tatcgttgat
    15481 aaaaacatgg atattttctt taggtgcttt tgcaatgcgt gagactactt cggtaacctc
    15541 gcgagctaat tgattttttt gttcttgtga gcgtccctca aacaagtcaa ttgttacaaa
    15601 tggcataatg ttactccttt atgttattgg gcatcattgt aacataatgc tgtgaaaaag
    15661 tatacactgt tttcaatggc tgggaaaact tcagcctttg tggtaaaata ggtagaatac
    15721 tatagaaagt aggattttcc gctttggctc aactctatta taaatatggg acaatgaatt
    15781 ctggtaaaac cattgaaatt ttaaaagttg ctcataacta tgaagaacaa ggcaaacctg
    15841 ttgtcattat gacaagtgct cttgatacac gtgatggttt tggcatcgtc tcaagccgta
    15901 ttggtatgcg acgagaagct atccccattt caaatgacat ggatattttc acatttattg
    15961 cccaattgga ggaaaaacct tattgtgtcc tgattgacga aagccaattt ttaagcaagc
    16021 aaaatgttta tgatttggcg cgtgtggtgg atgaactaaa tgttcctgtc atggcttttg
    16081 gtttgaaaaa tgatttccaa aacaatcttt ttgaaggttc aaaacatttg ctattattgg
    16141 ccgataagat tgatgaaatc aaaacaattt gccaatactg tagtaagaaa gcaaccatgg
    16201 ttttaaggac agaaaacgga aaacctgtct atgaaggtga tcagatacaa attggtggta
    16261 atgaaacata tatcccagtt tgtcgaaaac attattttaa tccagatatt taaaaggtaa
    16321 tcggttttaa aggagataca aagaaaaatg aatatttatg atcaattgca ggcagttgaa
    16381 gatcgttatg aagagttagg tgagttactt agtgatccag atgttgtttc agatacaaag
    16441 cgatttatgg aattatcacg tgaagaagct aatactcgag aaactgtcac agcttataga
    16501 gaatataagc aagtcattca aaccatttca gatgctgaag aaatgatcaa agatgccagt
    16561 ggtgatcctg aattagaaga aatggctaaa gaagaactta aagaatcaaa agcagctaaa
    16621 gaagagtatg aagaaaaatt aaaaatcctt ctattaccta aagatcctaa cgatgataaa
    16681 aacattattt tagaaattcg tggtgctgct ggtggcgatg aagcagcgct ttttgctggt
    16741 gatcttttaa caatgtatca aaaatatgct gaaactcaag gatggcgttt tgaagttatg
    16801 gaatcatccg ttaatggtgt tggtggtatt aaagaagtgg ttgccatggt ttctggtcag
    16861 tcagtttatt ctaagcttaa atatgaatca ggagctcatc gtgttcaacg tgtcccagtg
    16921 acagagagtc agggtcgtgt tcatacttca actgcaactg ttttggtaat gccagaagtt
    16981 gaagaagtag aatacgacat tgatcctaaa gaccttcgcg tcgatattta ccacgcgtct
    17041 ggtgctggtg gtcagaatgt caataaagtt gctactgcag ttcgtatggt acacattcct
    17101 acaggaatca aagttgaaat gcaagaagag cgtactcagc aaaaaaaccg tgataaagcg
    17161 atgaaaatca ttcgtgctcg tgttgctgac cattttgcgc aaattgctca agatgaacaa
    17221 gatgctgaac gtaaatcaac agttggtact ggtgatcgtt cagaacgtat tcgtacttat
    17281 aatttcccac aaaatcgtgt aacagatcat cgtattggtt tgacacttca aaaattagat
    17341 actattttat ctggaaaaat ggatgaagtt attgatgcac tcgttatgta tgatcagaca
    17401 aagaaattag aatctctcaa taactaatga actatgctac attaatcaga acttatgaag
    17461 ataaactaga acaaatagat gaggatcgcg aaaatctcgc ctatgttttt agagaaatca
    17521 aagaatggtc aagtctagat atgttgattc accaaaatca agctgtgact cctgaagatg
    17581 ctgttctttt ggaacatatt ttctgttctc taagtcagca tttatctcct caatatatta
    17641 caggtaatgc ttattttcgt gatttgaagc ttgcagtcga caagcgcgta ttaatcccaa
    17701 ggccagaaac agaagaatta gttgacatga ttttagctga aaatcttgat gcaccgttga
    17761 atgttttaga tattggtaca ggtagtggag cgattgctat ttctctcaaa aaagaaaggc
    17821 ctaactggca agtaacggca tctgatattt ctagagctgc tcttgacttg gcaaaagcca
    17881 atgctgatgc ttaccagctt gatataacgt ttattgaatc agatgttttt agtctcattt
    17941 caggaacctt tgatattatt gtgtcaaatc ctccctacat atcctacgag gataaggaag
    18001 aagtcagtct aaatgttttg caatcagagc ctcatttggc actttttgct aaagaaaatg
    18061 gctatgctat ttaccgtaag attattgaac aagctgacaa ttacttagct aaggaaggaa
    18121 agctttactt tgaaattggt tataagcaag ctgaaggtat aaaagatatg ttacaagcct
    18181 attttcctca aagacatata cgagtcgtaa cggatatatt tggcaaagaa aggatggtgg
    18241 ttgttgatta tggagtatct agctagtatc attgaatcag gtgatgccct tgttttgcca
    18301 acagaaacgg tttatggtct ttttgccaag gctttagatg aaaaagcagt aaatgctgtt
    18361 tatgacttaa aacaaagacc ccgagataaa gcaatgaacc ttaatgtggc tgattttaat
    18421 agtatcttag ccttttcaaa agaacagccg agatacctca agaaattata ccaagccttt
    18481 ttaccaggtc cgttaacgat tattttaaaa gctaatgacc aggttcctta ttggattaat
    18541 tcgggacttt caacggttgg ttttcgctta cccagtcatc caattaccgc agctttaatt
    18601 caaaaaacag gccctttaat tggtccttct gcaaacttat ctggcaaagc tagtggtcga
    18661 gtttttgatc atattatgca agattttgac tttcaagtgt ttggttatgc agatgatcct
    18721 tttctaacag gtaaggattc aaccatctta gacttatcag gtgagcgtgc tgtgatttta
    18781 cgtcaaggtg ctgtcaccaa agaagaatta ttagctaacg tgcctgaact tcgcttttaa
    18841 gagaggagcc gcttggaatg ttgagaccat taagtaaaac ggactgtcct atgctacaag
    18901 aaattaatgc caaagccctt ggctatttag tttcgcttga cttgttagaa aggcaatatg
    18961 aacgattgat tgaggattgc catcactatt ttttagctta tgccgacaag gataccaatc
    19021 aattattagg ctatgttcac gctgaacggt atgaaaccct ttatgcttct gatggtctta
    19081 atctcttggg cttggctgtt ttaccagcct atcagagaag gggaattggg agtgccttac
    19141 taagggccct ggaatcccaa gctaggcagg aaggcattgc ctttattcgc ctcaattctg
    19201 ccagtcatcg taaagaagcg catgcttttt accgaaacct cgactatgca gatgataaaa
    19261 cacaattacg attcatcaaa aacttacaag gagatgacaa tgatttttga taaaggtaat
    19321 gttgaagact ttgataaaga gctttgggat gccattcatg ctgaagaaga aagacaagaa
    19381 catcatatcg aattgattgc atctgaaaac atggtttcaa aagctatcat ggcagctcaa
    19441 ggttccgttt taaccaataa gtatgcagaa ggctatccag gtaatcgcta ttatggtgga
    19501 acagaatgtg tggatattgt cgaaacgctt gctattgaac gtgctaagaa acttttcggt
    19561 gccgcatttg ccaatgttca agcccattcc ggaagtcaag ccaatgcagc agcttatatg
    19621 gccttgattg aggctggtga caccgtatta ggaatggatt tggctgcagg tggtcatctc
    19681 acgcatggct ctccagtaaa tttttctgga aaaacctacc attttgtggg ttactcagta
    19741 gatgctgata ctgaaatgtt aaattatgag gcgattttag aacaagcaaa ggcggtccag
    19801 ccaaagctta tcgttgcagg ggcttcggcc tactctagaa gcattgattt tgaaaagttt
    19861 cgtgccattg ctgatcacgt aggtgcttac ttaatggtgg acatggctca catcgctggc
    19921 cttgtagcag caggtgtgca cccgagtcct gtctcttatg cgcatattgt gacatcaaca
    19981 acccataaaa ccttacgtgg tcctcgtgga ggcttgatat taaccaatga tgaagctctt
    20041 gctaaaaaga ttaattcggc cgttttccct ggtttacaag gaggacctct ggaacacgtg
    20101 attgctgcca aagcggttgc cttcaaagaa gccttggatc cagcctttaa agactatgca
    20161 caagctatta ttgataatac tgcggctatg gcagcagttt ttgcacaaga tgatcgtttc
    20221 cgtctgatct caggtggtac agataatcat gtctttttag tagatgtcac taaggttatt
    20281 gctaatggta aactagcgca aaatcttctg gatgaggtta atattactct aaataaaaat
    20341 gccattcctt ttgaaacctt atctcctttt aaaacatcag gcattcgtat tggttgtgca
    20401 gctataacca gtcgtggcat gggagttaaa gaaagccaaa ctatcgctca cctcatcatc
    20461 aaagccttgg ttaatcatga tcaagaaact attcttgaag aggttcgtca ggaagtgcgt
    20521 cagttaaccg atgccttccc actctataaa aagtaaggaa tcatgttaga tagttatata
    20581 aaacgtattg tcattcatca attttctccc aatgacactg agttactgtt atcagatcgt
    20641 ttagtgagca ttacaccacg aattgatgaa tatttccgga aaaaattggc taaagtgttc
    20701 tcggatgaag ccaaacgggg tcagtttgag gctaataata ccttttttac aaccattggt
    20761 gatgatttgt tggaaacgtc tgttaccatt gcccagttat ggaaggaagc ctttgttatt
    20821 tcagaggatc aaaaaaccaa tgatttagtc tttgtccagt ttgataagga tggcgaaccc
    20881 ttttttgctt tcttgcgaat tgctttgaaa gaacagtttg ctcacctttc tgacaattat
    20941 gaacatccat ttacggtgac gcagaataat ctgccgagtc ccacccagac accagatgaa
    21001 gcactagtca ttaatctcaa atctggtcag tactacttga ttgaaaagcg tgtgaagcat
    21061 aatggcagtt ttgctaatta tttttcagaa cacctcttga aagttacacc tgagcaatct
    21121 gttaaaaagt ctatcaaaat gatagaacaa accgctcaaa aaattgcaga gcattttaat
    21181 caagatgatt ttacttttca gtcaaagatg aaatccactc tttttaagca gttagaagca
    21241 gacgacgttt tatcaccaga aaaattagct gaccaactct ttgatgataa tttaacagcc
    21301 cgtttaacct ttgtggatca agtcaaagaa gtcattccag aacctataaa aattagcgat
    21361 attgatcatt ctagacagat aaaaaaacta gaaaatcaaa agctatcgtt atcaaacggg
    21421 atagaattaa cagtaccaaa tgccatttat caggatgctg aagcggttga atttttgtta
    21481 aatgatgatg ggacttattc aatcttgatt aaaaatatag aggatattaa aaccaaatag
    21541 atgtttagac ttttaaagcg tgcctgcagt tttcttcttc tttttgtcat ttatcaatct
    21601 tttgttattc atcacaatgt tcaacgtgtt ttggcatata agcctatggt tgagaaaaca
    21661 ttagcagaaa atgatacaaa ggcaaatgta gacttagtct tagctatgat atacaccgag
    21721 acaaaaggag gagaagcaga tgtcatgcaa tccagtgaaa gcagttcagg acaaaaaaac
    21781 tcgattacag atagtcaggc cagtattgag cacggggtga atttactgtc tcataatctt
    21841 gctctagctg aggaagcagg agtagattct tggacggctg ttcaggccta taattttgga
    21901 acagcttata ttgattatat tgctaaacat ggaggtcaaa ataccgttga tttagcgact
    21961 acctattcca aaaccgttgt ggcgccaagc ctaggcaaca ctagtggtca aacctatttt
    22021 tattaccacc ccctcgcctt gatttctgga ggtaagcttt ataagaatgg cggcaatatc
    22081 tattactcac gagaagttca tttcaatctt tatttaattg aactgatgag ccttttttag
    22141 aaagttatca tgaaacgatt acgcccatat gtgaaagggt acctaaaaga aagtatctta
    22201 ggtcctcttt ttaaattatt agaagcttta tttgaattat tagtcccttt gttaattgct
    22261 aacatgattg atatatcgat tagtcaacac aacagccagg gaattttgag ggttgtttta
    22321 acattatttg gtttagcaac cattggctta ttgctttccg ttacagccca gtatttttct
    22381 tcgaaagcag ctgttggttt tacaagacaa atgacagatg atttgtttaa aaaaatcatg
    22441 tttttgagca aggaggacca agaccatctt ggttatgcta gtctgttatc acgattgacc
    22501 agtgatagtt ttcaaattca aactggtatc aatcaatttt tgcgtctttt tctaagggcc
    22561 cctattatcg tatgtggtgc tatggtaatg gcttattgga ttagtccaag tctaacccta
    22621 tggtttgtga tgatggtgat tgtcttacta acacttgttt ttgttatgtc acatttatta
    22681 ggtccccttt atctcttaat ccgccgagaa acagatcact tggttcgttt gactagccaa
    22741 cagttacaag gaatccgagt aattaaggct tttaatcaaa cccaaaaaga actccaagca
    22801 tttaaggagc aaaatatgct cttaagtcgc caccaatatc aagctgctac cctagccaat
    22861 gtcttgaatc ctatgacttt tttagtggtc aatcttaccc tgttaatctt gatttggcaa
    22921 ggaagttggc aagtagctca tagatcgctt agtcagggca tgttggttgc tttaattaat
    22981 tacctcttgc agattttggc agaacttttg aaaatgacca tgttgatggg aaccatcaat
    23041 caaagtgtaa cagccgcaaa acggattaat caggtgtttg ttttagctga tgaagcgcct
    23101 ttgcccttac ttaaagatgg tcctatttca actcatctgt tggccatccg gcacttgacc
    23161 tttacttatc caggagcagc agagccaagt ctgtatgata ttcagttaag tgctgatcag
    23221 ggagaatgaa ttggcatcat tggtggtact ggagcaggca aaacgacttt gattgacttg
    23281 atctgccaaa cttattcaca atatagtggt gagattagtc ttaattggca aggagaagtg
    23341 ccaaaaacac taaccgagtg gcgaaatgtg attgctcttg ttcctcaaaa agctcaatta
    23401 tttaaaggaa cgattagaag taacctccta ctgggacaat caatgcctat taatgatgag
    23461 gagctgtggc gggctcttga attggctcaa gcaaaagagt ttgtcgctgc cttaccagaa
    23521 caattagagg cacctgttga agccttcggc tgtcattttt cagaagtgct ctggcaacgt
    23581 ctagccattg ccagagcact tctgaagcca aaacccattt tgattttgga tgatgccagt
    23641 tccgccttag acaatgagac tcgaggacga ctttttaaag ttctaaaaga agagttatca
    23701 gatgttttag tgattctagt cacgcaatcc attaagaatt tgcagtttgc tgataagatt
    23761 ttagtgttgg aacagggcca tcaattggat tttgccagtc atgaccagtt aaaagtaagc
    23821 aatgcacttt atcaagaaat gctagcgctt tacgtgaagg gggagcaaaa atgattaaaa
    23881 cagatcatca cctcctaaag cgagtgcttc aggatttgtt aaaaaaacct ctgcctgttt
    23941 gtattctcgt gatcgctagt tttgtacaag ttggtttaag tgtttacttg cctgttttta
    24001 tcggtaaagc cgttgatatg agtttgtcag tcaattcttg gcaaacttta aaatggctgt
    24061 tggggcaaat gttagttatt attgtggtca acacattgat tcaatgggtg atgcctcttg
    24121 tctatagtcg tttgctatat caatatagcc agcaattgaa agataagctt ttggaaaaaa
    24181 ttcatcgtct tccttttgca tatctagatc gtcaaaccat tggagatttg gttagtcgag
    24241 tgataaccga cactgagcaa ctgatcaatg gtctacaaat ggtttttaac cagtttatac
    24301 ttggactatt gacgattctg tgtaccatta tagctatggc acagattgac tggctcatgt
    24361 taatcttggt tttggtgtta acaccaagct ccctcttttt agctcgtttt attgctcaaa
    24421 agagttttca ttatgcacaa gcacagacca aaagcagagg aaatttagct cagtttactg
    24481 aagaaatcct tcgtcaagaa ggtttggttc aactgtttaa tgctcaagag cagtctatct
    24541 gtgattatca tgttttaaat aaaacctatt gcgagacttc acaaaaagcc attttttacg
    24601 cctcaacagt caatccagcc actcgcttta ttaatagtgt catttatgct ttactggcag
    24661 gtttaggggc ttttcgtatc atggctggac ttttttcagt aggtcagcta accacttttt
    24721 taaatgttgt tgtccaatat accaaacctt tcaacgatat ttcatctatc ttggcagaga
    24781 tacagagttc tttagcttgt gcgcaaaggc tttatgacct tttagatatt gaaataaaag
    24841 agcaagagca ctttctaaca tttaaggcat cagcggttaa ggggcaaatt gactttgaag
    24901 aagtaagttt ttcttatcaa aaagacaggc ccttactgaa agatattaat ttttctgttt
    24961 ctgcgggttc caaggtagcg attgtagggc ctacaggtgc aggcaaatcg actttaatca
    25021 atttactcat gcgcttttat gaacttgatg ctggtagcat caagttagat aaagttccta
    25081 ttaagtgtta tgctaaggaa gaacttaggt ccattactgg catggtattg caagaaacct
    25141 ggttgaaaga tgcgactgtt catgagttga ttgcttacgg cagtgaagag gctagccgtg
    25201 atgaagtagt ggcagcagcc aaagcagctc atgcacactt ctttattatg caacttccta
    25261 agacttatga tacttactta agtgcttctg atgatgcttt gtcccaaggg cagctccagt
    25321 tattagctat tgccagaatg tttttgaaaa aacctaaagt cttgatccta gatgaagcca
    25381 cctcctctat tgatattaga acagaagctg ttattcaaga ggcactaaaa gaactcatga
    25441 gaggaaggac cagctttatc attgcccatc gtttatcaac gattcaatca gctgatttga
    25501 ttcttgttat ggatcaaggt cgattggttg agtggggaac acatgccagc ttaatgtcaa
    25561 aaaacggatg ttatgctaga ttacaaaaga tagaataaag ttcgtctttt aacaaagatg
    25621 aactttttta gtcttcctaa agttaattaa ttaacaaatt ttaaactgtt atataaaaaa
    25681 taacagcgaa aaagcggacg atctttttta taagtgagaa aaaacagttg actaaagaag
    25741 aaataactca aaaaagtgag caatatattt ggaagcgttt tttgactgtg gtataataga
    25801 gccctatata atattgtgaa atgaggaaca aaatatatga gtaaaatcgt tgttgttggt
    25861 gcaaaccatg ctggtacggc ctgtatcaag actatgttaa caaactacgg tgatgctaat
    25921 gagattgttg tatttgacca aaactcaaat atttcatttt taggctgtgg tatggcactt
    25981 tggattggtg agcaaattgc tggaccagaa ggacttttct attcagataa agaagaatta
    26041 gagtctttag gggctaaagt ttacatggaa tcacctgttc aatcaatcga ctacgatgcc
    26101 aaaacagtga cagcgcttgt tgatggtaaa aaccacgtgg aaacttacga caagttgatt
    26161 tttgcaactg gctcacaacc tatcttacca ccgattaaag gtgccgaaat caaagaagga
    26221 tcacttgaat ttgaagcaac tcttgaaaat cttcaatttg tgaagttata ccaaaactca
    26281 gctgatgtga ttgcaaagct tgaaaacaaa gacattaaac gtgtagccgt agttggtgct
    26341 ggttacattg gtgttgagtt agctgaagct ttccaacgca aaggcaaaga agtgattctg
    26401 attgatgtcg tggacacttg cttggcaggt tattacgacc gtgatttgac tgacttaatg
    26461 gctaaaaaca tggaagaaca tggtattcaa ctagcctttg gtgaaacagt taaagaagta
    26521 gctggtaatg gtaaggttga aaagatcatt actgacaaaa atgagtacga tgtggatatg
    26581 gttatcctag ccgttggttt ccgtccaaac acaactcttg gaaatggtaa gattgagctt
    26641 ttccgtaatg gtgctttcct tgtcaataaa cgccaagaaa cttctattcc aggtgtttat
    26701 gctatcggtg actgtgcaac tatctacgat aattctactc gcgatacaaa ctacattgct
    26761 ttagcttcaa atgccgtccg tacaggaatt gtagcagcac ataacgcttg tggtacagac
    26821 cttgaaggta ttggcgttca aggctcaaac ggtatttcca tttacggatt gcacatggtt
    26881 tcaactggtt tgacacttga aaaagcaaaa cgacttggtt ttgatgctgc agtgactgag
    26941 tatactgata accaaaaacc tgaatttatc gaacacggta acttcccagt aaccattaag
    27001 attgtttacg ataaagactc acgtcgtatc ttgggtgctc aaatggcagc ccgtgaagat
    27061 atgtcaatgg gaattcacat gttctcactt gctatccaag aaggagtgac cattgaaaag
    27121 ttggcattaa ctgatatttt cttcttacca catttcaaca aaccttacaa ctacatcaca
    27181 atggcagcac ttggtgccaa agactagtat ctgataggaa aaagccagag cagttcagca
    27241 gcactggctt ttttgctttt taatttttgc aacccgaaaa gttctaaact tatgattatc
    27301 ctcttatagc acgttggaaa aggaatatca ggcaaaacaa aaagagaccg aagtctcttt
    27361 tgtgattagt ttttagcagc agaagcaaat tcttccttag caaaggcttc atcaatgata
    27421 gctttcaatt gatttgcaga ggcttgcatt ttttgcaatt cagcatcgtt aagtggaatg
    27481 tttactggac gaacaattcc atacgctcca acgatagctg gttgaccaat atagcaatct
    27541 tcaacacctt cgtattggcc ttcttggaaa acagaaagcg gaagaacagc attttcatca
    27601 tcaagaatag cttttgtaat acgagctagg gcaactgcaa taccgtagaa agtagcacct
    27661 tttttattga tgattgagta agcagcatca cgtacagaaa tgaaaagatc aactaggcct
    27721 tgctcatcaa tgtcacgatt agcttggagc cagtcgtaaa gacctacacc agcaacgtta
    27781 gcgtgtgacc aaacagcaaa ttcagagtca ccgtgttctc ccatgatgta agcgtgaacc
    27841 gaacgcgcat caacaccgat tttagcagcc agagcttgac ggaaacgggc tgaatctaga
    27901 gatgtacctg aaccaatgac acgctcttta gggaaacctg agaatttcca tgttgagtaa
    27961 gtcaaaacgt caactgggtt agcagcaaca agaaagattc ctttgaaacc agatgcaacg
    28021 atttgtgtaa caacctcttt attgatacga aggttttttt caacaaggtc aaggcgtgtt
    28081 tcacctggtt tttgaggagc accagctgtt aagacaacaa gatcagcatc atgacagtct
    28141 gagtagtcag ctgcatagat ttttttaggt gatgtaaaag ctagagcgtg gcttaaatct
    28201 tctgcatctc cttgagtttt ttctttaaaa atatcaataa taccaagttc ttgagcaata
    28261 ttttgtgtta ccaatgcaaa agcgtatgat gaaccgacgg caccatcacc gaccaagatt
    28321 acttttttgt gttgtttagt tgcagtcatt tctaaacatc tccttaattt tattagagca
    28381 aaagctcata cggtcttatt ttaacatatt gataattgtt tgtcattgaa ttcagaaaaa
    28441 taatgaaaat agtttactga taacgcttcc aataagaaaa aataaggaat ttatggtata
    28501 atgaaatcta gtattgacta gaaaaggagc attccttaaa tgcaagatcg aaatttaatt
    28561 gacgtcaatc tgacaagtga aatgaaaacg agtttcattg actatgccat gagtgtcatt
    28621 gtggcaagag ctttgccaga tgtgcgtgat ggtctgaaac ctgtgcatcg tcgtattctc
    28681 tatgggatga atgaactcgg tgtgacacct gataaaccgc ataaaaaatc tgctcgtatt
    28741 acgggtgatg tcatgggtaa atatcacccg catggggatt cttctattta tgaagctatg
    28801 gttcgtatgg ctcagtggtg gagttatcgc catatgcttg ttgatgggca tggcaatttt
    28861 ggttctatgg atggtgatgg tgctgccgct caacgttata ctgaagcgcg catgagtaaa
    28921 attgcgcttg aattattaag agatatcaat aaaaataccg ttaattttca agataactac
    28981 gatggaagcg aaagagaacc agtagtatta ccagctcgct ttcctaattt attagtcaat
    29041 ggagcgacag ggattgccgt tgggatggca actaacattc cgcctcataa tttggcagag
    29101 tctattgatg ctgtcaagat ggtaatggaa catccagact gtacaacaag agagttgatg
    29161 gaagtgatcc ctggacctga ctttccgact ggtgcccttg ttatggggcg ctcaggtatt
    29221 catagggctt atgatactgg taaaggttct atcgttttac gctctcgaac agaaattgaa
    29281 acaactcaaa caggtcggga acgtattgtg gttactgaat ttccctatgg cgtcaataaa
    29341 acgaaagtgc atgaacacat tgttcgttta gcacaagaaa aaagactaga aggtattaca
    29401 gcagttcgtg acgaatctag ccgtgaagga gtgcgttttg ttatcgagat tcgtcgagag
    29461 gcatccgcga cagttatctt aaataacctc tttaaattaa caagccttca gacgaatttc
    29521 agttttaata tgttggctat tgaaaatggt gtgcctaaaa tattgtcact cagacaaatc
    29581 attgataatt acattagtca tcaaaaagaa gttattatac gtcgcacccg atttgataaa
    29641 gataaagctg aagccagagc tcatatttta gaaggcttac tgattgccct tgattattta
    29701 gacgaagtga ttgctattat tcgtaacagc gagacagatg tcattgctca gacagaattg
    29761 atgtcacgtt tcgacttgtc tgaacgccaa agccaagcta ttttggatat gcgtttgcgt
    29821 cgtttgactg gtttggaacg tgataagatt caatcagaat atgatgattt gttggccttg
    29881 attgctgact tatctgatat tttagccaaa ccagaacgta ttatcactat catcaaagaa
    29941 gaaatggatg agatcaagcg taaatacgct aacccacgcc gtacagaatt aatggtcggt
    30001 gaagtccttt ctctagaaga tgaagaccta attgaagaag aagatgtttt gattaccttg
    30061 tcaaataaag gttatatcaa gcgtcttgct caagatgaat ttcgtgccca gaagcgtggt
    30121 ggacgtggcg tccaaggaac tggagtcaac aatgacgact ttgtacgtga attggtatca
    30181 acaagtaccc atgatacttt gctcttcttt acgaattttg ggcgtgtcta tcggttgaaa
    30241 gcttacgaaa ttccagaata tggtcgtaca gcaaaaggtc ttccaattgt taatctattg
    30301 aaattagaag atggtgaaac cattcaaact attatcaacg cacgtaagga agaaacagca
    30361 ggtaaatcct tcttctttac aacgaaacaa ggcattgtca aacgtacaga agtttcagaa
    30421 tttaataata tccgtcaaaa cggtctccgt gctcttaagt tgaaagaggg agatcagctg
    30481 attaacgtcc ttttgacaag cggtcaggat gacattatca ttggaactca ttccggatat
    30541 tctgttcgtt ttaatgaagc aagcatccgc aacatgggcc gatcagctac gggtgttcgc
    30601 ggggttaagc ttcgtgaaga tgatcgcgtt gttggcgcgt cacgtattca agataaccaa
    30661 gaagttcttg taattaccga aaatggcttt ggtaagagaa caagtgctac agactatcct
    30721 acaaaaggta gggggggaaa aggaataaaa acagctaata ttacccctaa aaatggtcaa
    30781 ttagctggat tggttaccgt agatggtaca gaagatatca tggtgattac aaataaaggt
    30841 gtcattattc gcacaaatgt tgcaaatatt tcgcaaacag gtcgtgctac tttgggtgtt
    30901 aaaattatga aactagatgc tgatgctaag attgtaacat ttaccttggt tcagcctgaa
    30961 gacagtagta tcgatgaaat caatactgat cgtgaaaata gtatttcaaa aaaataaaga
    31021 taattaatca taacaaggag taaaaaatgg taaaaaaaca aaagcgtcga aaaataaaat
    31081 ccatgtcttg ggcaagaaaa ctactaatag ctgtactttt aattctaggt ttagcattgc
    31141 tttttaacaa acctatccga aatacattaa ttgctcgaaa ctctaataaa tatcaagtaa
    31201 cgaaagtttc gaaaaaacaa atcaaaaaga ataaagaggc taagtcaaca tttgatttcc
    31261 aagccgtaga gccagttagt acagagagtg tcttgcaagc acaaatggcg gctcagcaac
    31321 ttcctgttat agggggcatt gccataccag agcttggcat taatttacca atttttaaag
    31381 gtttaggaaa tactgagctt atttatggcg caggaacgat gaaagaagaa caagttatgg
    31441 gaggagaaaa taattattct cttgccagtc atcatatttt tggaattaca ggttcatctc
    31501 aaatgctctt ttcgccgctt gaaagagcac aaaatgggat gtccatctat ttaacagata
    31561 aagaaaaaat ttatgaatac attataaaag atgttttcac ggtagctcct gaacgcgttg
    31621 atgttatcga tgatacagct ggtctcaaag aagtgacttt agtgacttgt acagatatcg
    31681 aagcaacaga acgtattatt gtcaaaggag aactaaaaac agaatacgat tttgataaag
    31741 cgcccgccga tgtattgaaa gcttttaatc attcttataa ccaagtatct acctagatat
    31801 atcttaaata taatatttaa aaagtaggac catagagaaa atttatctca tcctactttt
    31861 tttgaaagga gaaatattat gaaactaaat gccattcacc acgttgctat tattgtatct
    31921 gattataatc tgtcaaaaaa tttttatgtg aataaactcg gatttgaaat tatcagagaa
    31981 aattatcgtc ctgacaagca tgattacaaa ttagatttat cttgtggtcg tattgaattg
    32041 gagatttttg gtaaggtgac aagtgacccc tactatcaag ctcctcctaa acgtgtaagt
    32101 caaccagaat ttaaaagtga ggcctgtggt ttgaggcacc ttgcttttcg tgttaccaac
    32161 attgagagtt atgtagatga tctaaagagc ttaggaattc tagtggagcc tatcaggcat
    32221 gatgattaca caggtgagaa aatgactttc ttttttgatc cggatggttt gcctttagaa
    32281 ttacatgaat agacttatta ggttaacgac tggatcgtgc tataaaactc gttaaaaata
    32341 gttatttgtt gtatcttcat ttgcttgatt aatctctttt gatcgttaaa tgatttggtt
    32401 aactttcaaa gtgaagagca atttttggag taatcttgtc gaagtttttt aatagaataa
    32461 ctatagaaaa agcaaaatat ttgacgataa actcttacag tgttataatg acaatataag
    32521 ttaataactg tgttgtcact ttgttgaaat gttttcgtat taatgttttt tttatctatt
    32581 acgatagata attttacttc aatttttgat tgaaaatact aaaataagtg atgtggtcac
    32641 tttgacaacc atttattggt ccttttagat aagacaattt tgtggctctt cagttgaaag
    32701 gatgtgttgt tgatgttaga ggaaacaatc atgttaaatt aactcaggct taaagaccaa
    32761 aaaaggagtg aagtctatta tgaaaaaaag aaattttaaa cttacagaaa tgttacaatt
    32821 ggttttatta gtggttcctg ctgtaaaact tgctaaaaaa atgtttaacg atagtaaaac
    32881 accgtctaaa agaaagtagg tctacaatga ctaaaaaaaa tcatggcgtt ttttgggggt
    32941 tgttgcttgg atcagcagca gctagcattg cttacttaag tttatcgtct tccaaaaaag
    33001 atcaactctt gaaagatagt gctaaaaaaa tagatgatct caacgcttac ttgcaagata
    33061 aaagtaagca agttctggat gcagtatcgg aaaaagtaca agaatccaaa gatgctgttg
    33121 aagtttatgg tggtattgcc gcagaaaccg ttgaagaaaa gtggcaagat accaaagatg
    33181 ctgttgaagt ttacggtggt attgccgcag aaacagttga agaatctttg ggacaggcta
    33241 aagaaaaggt agaaggaatt ggcgaagcta ctagtcaaac tatccaatct aaaatggaaa
    33301 aactcaccag cgataagaca gatgctgatg atgatgatga aaaataggtt ttaaaatacc
    33361 tttaagataa gacaaaaagt gccattaggc acttttttaa tcttctgttg gaacaataat
    33421 cgaaatggct tttggaatga tatctaattg aatgggcaga tagtcacttt tatccccatc
    33481 aatcctggta cgtggtaata tcgcttgttt tttagcttgt ggtagtaagc taagcgtatt
    33541 ggcttgaaaa tgactgattt cctctgcttt ggaaaaatca ccctgtttaa aatcattaat
    33601 atgccataaa aatttaaaga aagagacttt tttcatggta taaacttgga aatagccatc
    33661 gtcagcttga gcaccaggag aaaaagaagg aaaaccagca atggtatttg tcatcgtgat
    33721 taagagaaac ttcgttttca ggtgaatacg atggttgtgg ctaattaaag agatggcata
    33781 gctgcgattt cgtttcagta ttcgaatact atcttttaaa aatgctaaag gaccaaagcg
    33841 tcgtttttcc tcagccgtta cgtcggcagc aatatcagcc agtaatccta aggttaaact
    33901 ggaaatcatg tattgctggt tagctttgca aatatcaact tgcatgattt gtccagtcaa
    33961 gatagtatcc aacgcctcag taatttgtaa agggatatgc atagccttgg caaaattatt
    34021 gactgtccct gagggcacta agcctattaa acaatgagct cctccttcat agatgccacc
    34081 gatgatttta tttagtgtcc catcgccacc aagagggata accaagtcaa tcttgtcctt
    34141 agcagcttgt tttgctaatt gaaaagcctg gtcagcatct ttaggggtaa taacttctac
    34201 agaatcttcg gaaaaaccat gttggcaaaa atagtctttg acttgcccag caagttggtc
    34261 ttctttcttt ccagaattag gattgtaaaa aatccgaacg gttttcatca ggtctctcct
    34321 ttgacaactt attacttgct atccattata ccacttctaa gaattgatgt cttacatcaa
    34381 atcatcacat taagcctctc aatcagtctg agcatctatt tgtcttaaag cataaagaaa
    34441 gtgatagcga taaattggag ggcagaggcc aataaaataa agagatgcca aatcatgtgg
    34501 aagtagggtc tttttttggc ataaaatacc gctccaatgg tataagacaa gccaccaaat
    34561 aacatgagaa gaccaaaagc aagactagtt ttttgaatga tgactggcaa gataaacaca
    34621 acgagccagc ccataacgat ataaagcatc aaactgaatt tttcattgat acgtttggca
    34681 aaaattttgt ataaaatccc aaaaagcgta atgccccact gtaaaacaat aatgatatag
    34741 cctagccaac cagaaacaag ggataaggca acaggtgtat aacttcctgc gatagcaatg
    34801 taaatcatac tgtgatcaat aatgcgtaga atgtatttgt gaaccgaacc ataagccatg
    34861 gagtggtaaa tcgtagagga caaaaacatc aaaaagagac tgatgacaaa gatggagata
    34921 ccaatagcgg ctttaaggtc ataagtttga taagcatagc tggctgaaat aggaagtaga
    34981 atgagcatag caaatgctcc gatagcgtgt gtcacgctgt ttgctacttc ctcactaaaa
    35041 gataagggta aactttgttt aaaggtttgg ttcattgggt cacctcctgt gataaataaa
    35101 tagttttgtg gtaatctttg accgtttgac aggcaacctg cacaatcggt ggaatgtcct
    35161 cctcaatggg agccttctga ttccaacagg ttacaaaagt attgtaaaga ctttcagaat
    35221 cagcctgtgc ctgaagttcc tccaatacgc gactaatatc ttgaatagga aataccgttt
    35281 taaacaaact gatggcaatt aagcgcgcta gttgttgctt ttggtatttt ttcttgatag
    35341 gtttagtcac atacccatgc ttgacgtaat tattaatcat agatgccgtt agtgatttat
    35401 tatctgacac ttctgaaaaa tcagtgcact ggttgacata aagtaagact tgatccaaat
    35461 ataagtctaa atcagggagg tccttccaat aaggtaatga tggaaaaatc atagtttcgt
    35521 ctctctatct agttttgata actagattat atgattaatg aaaacttatt gcaagcaaaa
    35581 actgtaaaga cttaaaagag gaaagtagaa atggcgaagt gaagctaatc atgctataat
    35641 gttaaagaat tgattgggat agatgccttc tgtcgcaatc agactatttt atcacgaaga
    35701 agatgatgct acgaaaggaa tgatacactc atggtaatga ttcaatggtt tcctgggcac
    35761 atgtccaaag ccagaagaca ggttcaggaa aatttaaagc atgttgactt tgtaactatt
    35821 ttagtggatg cacgcttgcc actttctagt caaaatccca tgctcaccaa aattgttggt
    35881 gataaaccta aattaatgat tttaaataaa gctgacttgg cagatgcaac tcgaactaaa
    35941 gagtggaaag cctactatga aagtcaaggc attaaaacac tagccatcaa ttctaaagaa
    36001 caatcaacag ttaaaaaagt aacagaagca gccaaggaac tcatggctga taaaattaag
    36061 cgcctgcgtg atcgtggtat tcaaaaagaa accttacgaa ccatgattat tggcattccg
    36121 aatgctggta aatctacctt gatgaatcgc ttggctggta agaaaattgc tgtggttggt
    36181 aataaacctg gtgtgaccaa agggcaacaa tggctgaagt ccaataagga attggaaatt
    36241 ctagataccc ctggtatttt atggccaaaa tttgaggacg aattggttgg cttaaaatta
    36301 gctttaacag gtgctatcaa ggaccaatta ctaccaatgg atgaagtgac tatctttggc
    36361 ttgaattact ttagggaata ctaccctaat cgtttaacca aacgttttaa gaatattcct
    36421 cttgaggaag aagctcctga aatcattatg accttgacac gccaacttgg atttaaagac
    36481 gattatgacc gtttttacac tttattcgtt aaggaagttc gtgatggtaa attaggtcaa
    36541 tacaccttag atcaggtggg agatatggat gccgactagt attaaagcta ttaaagaaag
    36601 cttagaggcc gttactagcc tcttggaccc cctctttcaa gaattggcaa ccgacactag
    36661 gttaggcgtc caaaaagctc taaaaagccg acaaaaggct attcaggccg agttagcaga
    36721 agaagaacga ttagaagcca tgctttctta tgaaaaggct ctttataaaa aaggttatca
    36781 agccattgca ggtattgatg aggtgggacg tggtccctta gcaggtcccg ttgtggcagc
    36841 ttgtgtgatt ttacctaagt attgtaaaat taaaggcctt aatgattcta aaaaaatccc
    36901 taaagctaag catgagacca tttatcaggc agtgaaagaa aaggctttgg ctatcggtat
    36961 cggtattatt gacaatcagc tgattgatga ggtcaatatt tatgaagcaa ccaaactagc
    37021 tatgctagaa gccattaaac agttggaggg ccaactcaca caaccagatt atctcttgat
    37081 tgatgccatg acattggata ttgctatttc gcagcagtct attattaaag gcgatgccaa
    37141 ttccttgtct attgcagcag catcaattgt agctaaggtc accagagatc agatgatggc
    37201 taactatgat cgcatttttc ctggttatgg ctttgctaaa aatgcaggct atggcaccaa
    37261 agaacattta cagggattaa aagcttacgg cataacgcct atccatcgta aaagttttga
    37321 acctgttaaa tccatgtgct gcgattcaac taatccttaa aaagttctgt ttttagcaga
    37381 atttttttct tttttacgaa taaatgaagt aaggaggtaa cttagtgaat cattttgaac
    37441 tttataagct aaagaaagct ggactgacta ataaaaacat tctcaatatt cttgactacc
    37501 aagaacacca ggaaaaatcg ttgtcacttc gagatatggc tgttgtttct ggttgtaagc
    37561 atccgtctca ctttatagaa gcctataagc agttagatat tcaaaaatta aaaatggaat
    37621 ttaaacaatt tcctagtatt tctatcttag ataagcatta cccaatggca ttgaaagaaa
    37681 tatacaatcc acctgtcctc ttgttttttc agggaaattt agaccttctt gagaaaccta
    37741 aattagccat tgtcggctcc agacgctcaa gcgatactgg agtaaagtct gtccgtaaaa
    37801 ttcttaaaga actcgggaat cgttttgtga ttgttagcgg acttgctcga ggtatcgaca
    37861 ctagtgctca tttagcctgc cttaaaaatg ggggacaaac tatcgctatt attggaacag
    37921 gattggatcg cttttaccct aaagaaaata gggagttgca aactttctta gggaaaaatc
    37981 atcttgtgct aacagaatac ggtccaggag aagaagcttt atcttatcac tttccagaac
    38041 ggaatcgtat tatcgcaggc cttagccgag gtattcttgt cgttgaagca aaaaatcgtt
    38101 caggttcctt gattacttgt caaattggga tagaagaagg ccgagacatt tttgctgtcc
    38161 caggaaacat tttggacggg aaatccgaag gttgccttca gttaattaaa gagggagcaa
    38221 catgcgtcac atcgggcatg gatatccttt cagagtacta aaaaagttaa agtttcttcc
    38281 tatatagcat tttttttatt gacagtttct taaaaatggg atattatgct ataagcttta
    38341 aacaaactgt tataggaagt gtgtcgaatt gggaacaaaa actacaacta agccaaaaac
    38401 gggtactaaa aagtccacca ctaaaaagaa atcaacagcg aaaaaaaatc tcgttattgt
    38461 tgaatcacct gccaaagcta agactattga aaaatatctt ggacgcagtt ataaagttgt
    38521 tgcttcggta ggacatattc gtgacttaaa aaaatcgtct atgtctattg attttgataa
    38581 taattatgag ccacaataca ttaatatccg tggtaaggga tcccttatca attctttaaa
    38641 aaaagaagcc aaagctgcta aaaaagttta tttagctagt gacccggatc gtgagggaga
    38701 ggctatttct tggcatttgt cacatatctt aggacttgat cctcaagata ataaccgagt
    38761 ggtttttaat gaaattacga aagatgcagt taaacatgcc tttgtggagc ctcgtcagat
    38821 tgatatggac ttggtagatt ctcaacaagc acgtcgtgtt ttggaccgta ttgtgggata
    38881 ttccatttca ccaattcttt ggaaaaaggt caaaaaagga ctttcagcag gacgtgtcca
    38941 gtcggttgct ttaaaactca tcattgaccg tgaaaatgac atcaaagcat ttgttccaaa
    39001 ggaatactgg tctattgatg gtctttttaa aaaaggaact aaaaagtttc aagcgacttt
    39061 ttacggtatt aatggcaaaa aaacaaagct tgataataac aacgatgtca aagaggtatt
    39121 agcaaagcta acaaatgaag attttcttgt cagcaaggtt gacaagaaag agcgacgtcg
    39181 taatgctccc ttaccttaca caacatcatc tcttcaacaa gatgctgcta ataaaatcaa
    39241 tttcagaacg cgtaaaacca tgatggtagc ccaacaactg tatgagggga ttcatttagg
    39301 agaaaacgga actcaaggtt taattaccta tatgcgtact gattctactc gtatcagtcc
    39361 agtagcacaa aacgatgctg ctcaatttat tatcaatcgc tttggagcta attattcaaa
    39421 acatggtaat cgtgtcaaaa ataccagtgg tgcccaagat gctcacgagg cgattcgtcc
    39481 atctagtgtt aatcatacgc cagactctat tgccaaatac cttaacaagg atcagttaaa
    39541 actttatacg cttatttgga atcgttttgt ggctagccaa atgacagcag ctgtttttga
    39601 taccgtaaag gtaaacttgg agcaaaatgg cgtgcttttt gttgccaatg gtagccaaat
    39661 gaagtttgat ggttacatgg ctgtttacaa tgattccgat aaaaacaaaa tgttacctga
    39721 gatggcagaa ggagaaacgg ttaaaaaaat atcgacctct ccagaacagc actttacgca
    39781 gccaccagct cgttattctg aagcaactct gattaaaacg ctagaagaaa atggtgttgg
    39841 acgtccatca acttacgctc caaccttaga agtcattcaa cgcagatact atgttaaatt
    39901 gtctgctaag cgctttgagc caactgagct tggggaaatt gtcaacaagc ttattgtcga
    39961 atttttccca gatattgttg atgttgcctt tactgccgag atggaaggta agctagatca
    40021 agttgaaatc ggtgaagaag aatggcaaca tgtcatcgat caattctatc aaccctttgt
    40081 caaagaattg aataaggctg agtctgaaat tgaaaagatt caaatcaaag atgagccagc
    40141 tggttttgac tgtgatgttt gtggccaccc aatggtcatt aagttaggac gttttgggaa
    40201 attttacgcg tgtagcaact tcccagagtg ccgtaataca aaagccatca ctaaagaaat
    40261 tggtgttact tgtccggttt gtcataaagg acaagttatc gagcgtaaaa ccaaaaaaaa
    40321 taggatattt tatggttgtg atcagtatcc agattgtgag tttatctcgt gggatttacc
    40381 tattggacgt gcttgcccta agtcaggtga ctatcttatt gagaaaaaag ttcgtggtgg
    40441 caaacaagta atgtgtagca atgagacctg tgattacaag gaagaaaaaa ttaaataaaa
    40501 aaagaattgg aactccttgt cttgttccaa ttcttttttt atttacaaag gtatttttaa
    40561 ctacaaaaat cgctagttcg tttttaaaag gcttaaaaat tcctcaataa ctggactgaa
    40621 actcgcatca tctcggtaag caatcccaat agggtaaaaa ttatttttat cttgcaaagg
    40681 aatccaaact aagttatcta cctgattaag actctcaaaa tcactcggga ggatagtcaa
    40741 ggtatttaaa tcgtgcaaac tatgaataag aacttcccaa tcattgtgtt taaagacaat
    40801 atctggttca aaaccgagag ctcggcattt tctaggaagc atttcgccta acatgtagtg
    40861 atcgtttaaa gaagcaatct tatagccttt taaatcttta agttttaact gaggatgttg
    40921 cgccaaaggg tgctgtttga ggagaacgat actgacctta tagccttttg tggacgtttg
    40981 taatagctca atggtaatat ccttttgaat acttagaaag gagaggagac caatatcgat
    41041 ttttccttgg gacaataatt cttataattt gcgagaacca tcctgtataa gcgataattc
    41101 aacatttgag tgagtagcca taaagattga aatttgtttc atgaattgta tagcaaacag
    41161 tgatgttaat tcaacacgaa tcatctcttt ttttcttgat ttaattgctg aatatccgca
    41221 acaatttgat taaaatcatc cacaaggtct ttgcctttgt gataaagaat atctccagct
    41281 tcggttagta gtagctgtca atcactttgt gtaaaaagcg tcgtgttcaa actaggactc
    41341 tagcctttta attgattgag aaagagtagg ttgcgttaca aacaaacttt tagcagcgtg
    41401 ggaatgattt tttgtttcag caactgcaat aaaataggtt aattatctaa tatccatagt
    41461 agatccttca tgattggtca aggaatagcg tctctacttg gtttacaacc tattttgatg
    41521 tctctcctta ttgccatgat tttctgcttc cttattgttt ctccaattac aacggtagga
    41581 attgctcttg cgattaactt atctggtatt ggttcaggtg ccgcaagctt tggactttgc
    41641 ttagcaggtt gggctgttaa ttcaaaagga acttcacttg ctcacgtctt gggatcaccg
    41701 aaaatttcaa tggccaacgt tttatcaaaa ccaaaaatca tgttgccaat gttatgttct
    41761 gcagctgtac ttggtgttat tggtgctatc tttaatattc aaggaacacc tgctagtgca
    41821 ggctttggga ttagttgttt gatcggacct atcaatgccc ttaatttagc taaaggcgga
    41881 tggtctctag taaatatcct acttatcatt atcatttttg taggggcacc aattgttctc
    41941 aatatgatct ttaactacct ttttatcaag gtgcttaaag tgattgatcc aatggattac
    42001 aaacttgata tctaagaaag gaacttttga tgaaattaaa attatataat gttagaggcg
    42061 aagaagcagt cttagcaaaa aaatgggctg atgacaatga gattgagatt tccttgacgg
    42121 agtctccctt aactcctgaa acggttaaag aagctgaagg ctttgacggg attgccaatg
    42181 cccaaattgg tcctttagat gatgcgattt atcctctctt aaaggaaatg gggattaaac
    42241 aaatcgctca gcgcagtgct ggtgtcgata tgtataacct tgatttggcc accgaaaatg
    42301 acattattat cacaaatgtt cctagctatt ctccagaatc cattgcagaa tttacggtta
    42361 ctattgccct taatttaatt cgtcatgtgg agttgattcg tgaaaatgtt aaaaaacaaa
    42421 atttcacttg gagactccct atccgcggcc gtgttttagg tgatatgaca gttgcgatta
    42481 tcggaactgg ccgtattggt ctagctactg ctaaaatctt taaaggtttt ggctgcaagg
    42541 tcgttggata tgatatttac caaagcgatg ctgccaaagc tgtcttggac tataaggaat
    42601 ctgtagaaga agcgattaaa gatgctgatc ttgtttcctt acacatgcca ccaactgcag
    42661 agaacacaca ccttttcaat tctgatttat ttaaatcatt caaaaaaggg gctattttga
    42721 tgaatatggc gcgtggtgct ctcattgaga cgcaagattt actggatgct ttggatgcag
    42781 gcttactgag cggagctggt attgacactt acgaatttga aggaccttat atacctaaga
    42841 attttgaagg tcaagaaatt acagatgcac tatttaaagc tttgattaac catcctaagg
    42901 ttatttatac acctcatgca gcttattata ctgatgaagc cgttaaaaac ctagttgaag
    42961 gtgcccttaa tgctacagta gagattatca aaactgggac aacgacaact cgtgttaact
    43021 aacaactgat ttgacgtcca ttataaagga ataattctaa aaattccttt ataatggact
    43081 tttttgcatt agtccgttat aatagactgt aagaaagggg actcttatga catatatagc
    43141 gcttattgga gatattatcc agtccaaaca attgacggat cgttccaaag ttcaaaaaac
    43201 tttagcagct tatttagacg acctcaacaa aacctttgct ccttatatta tttctaaatt
    43261 atccctaacg ttgggagatg aatttcaagg actttttcag gtggatactc ctattttcca
    43321 tctgattgat ttgattaatc atcacatgga tatccctatt cgatttggag taggagtagg
    43381 ttctattcta acagacatca atcctgatat tagtattggg gctgatggac ctgcttattg
    43441 gcatgctcgt gaggctattc gttatattca tcaaaaaaat gattatggta atactacatt
    43501 agctcttcgg actggtcatc acaaccagga tgatgtatta aacagtttac tagcagctgg
    43561 agatgctatt aaagccaact ggcgagctag tcaatgggaa atttttgaca cgcttttaga
    43621 tttgggcatt tatgaggaat actttgatca acaacgacta ggaaagcaat tatctcttag
    43681 ctctagcgct ttgtcaaaac gtctaaaaag tagtcatgtt aaaatttatc tgagaacacg
    43741 gcagagtgcg ctaaactgtc tcaaacaaat caaggaggaa gctgatgatt aatggtgttt
    43801 ctcactacct agctcaaacc cctaccctta ccctgtttct catttgtcat gtgttatcag
    43861 actaccagtt acaaagtcag caagtagctg atttaaaaga aaaacatttg acttatttag
    43921 gttaccactt gattggagtt agcattcccc taatttgttt aaccctcatt atcccacaag
    43981 catggttgat gagccttttg gttatgataa gtcacgcgct tattgactgg ctaaagccac
    44041 aggtggctaa ctctctaaaa tggaaaagag agtggatttt tctgctggat caatgcttac
    44101 atatcgctat tagttcattt gctgggctaa gattagcagg ggtgaccttg cctaattggc
    44161 ttccgatacc tattttgatg accgttttat ttatcctact cattaccaaa ccaactaata
    44221 ttgtctttaa actctttttc agcaaatacc agcctgacca aggagaaaaa atggacacga
    44281 tcataggagc gggggctacc ataggaattc tagagagaat tgttattggt gtgtgtatga
    44341 tcatggggca atttgcttca ataggtctgg tctttaccgc taaatctatt gctcgctaca
    44401 ataaaatttc ggaaagtcca gcttttgcag aatactacct gattgggtct ttatttagta
    44461 ttctcagtgt ttttatcgca gcatggattt gtttcttcta gtcgaaaagg gttcccgtag
    44521 aaagaggcta acgcttagtc tctttctttt tctttcttct tatttctgtt ataataagtc
    44581 aggtaactac attagaaaga tttgtgggtc tgtcatctaa gagatgtcat tcccgaagag
    44641 gtattagtga cttgtctcaa tcaactgcaa cttatattaa tgttattgga gctggactag
    44701 ctggttctga agctgcctat cagattgcta agcgcggtat ccccgttaaa ttgtatgaaa
    44761 tgcgtggtgt caaagcaaca ccgcaacata aaaccactaa ttttgccgaa ttggtctgtt
    44821 ccaactcatt tcgtggtgat agcttaacca atgcagtcgg tcttctcaaa gaagaaatgc
    44881 ggcgattaga ctccattatc atgcgtaatg gtgaagctaa tcgtgtacct gctgggggag
    44941 caatggctgt tgaccgtgag gggtatgcag agagtgtcac tgcagagttg gaaaatcatc
    45001 ctctcattga ggtcattcgt gatgaaatca cagaaatccc tgacgatgcc attacggtta
    45061 tcgcgacggg tccattgact tcagatgcct tggcagaaaa aattcacgcg ctaaatggtg
    45121 gcgacggatt ctatttttac gatgcagcag cgcctatcat tgataaatct accattgata
    45181 tgagcaaggt ttaccttaaa tctcgctacg ataaaggcga agctgcttac ctcaactgcc
    45241 ctatgaccaa ggaagaattc atggctttcc atgatgcact aacaaacgca gaagaagccc
    45301 cgctgaatgc ttttgaaaaa gaaaagtatt ttgaaggctg tatgccgatc gaagttatgg
    45361 ctaaacgtgg cattaaaacc atgctttatg gacctatgaa acccgtcggc ttggaatatc
    45421 cagatgacta tacaggtcct cgcgatggag aatttaaaac gccatatgcc gtcgtgcaat
    45481 tgcgtcaaga taatgcagct ggaagccttt ataatatcgt tggtttccaa acccatctca
    45541 aatggggtga gcaaaaacgc gttttccaaa tgattccagg gcttgaaaat gctgagtttg
    45601 tccgctacgg cgtcatgcat cgcaattcct atatggattc accaaatctt ttaacggaaa
    45661 ccttccaatc tcggagcaat ccaaaccttt tctttgcagg tcagatgact ggagttgaag
    45721 gttatgtcga atcagctgct tcaggtttag tagcaggaat caatgctgct cgtttgttca
    45781 aaagagaaga agcacttatt tttcctcaga caacagctat tgggagtttg cctcattatg
    45841 tgactcatgc cgacagtaag catttccaac caatgaacgt caactttggc atcatcaaag
    45901 agttagaagg cccacgcatc cgtgacaaaa aagaacgtta tgaagctatt gctagtcgtg
    45961 ctttggcaga tttagacacc tgtttagcgt cgctttaaca ctaaaaaaga gttccttttc
    46021 agttgagttg ctgaagagga cttttttact tgctgatttg agcgctagct atgcaaaaga
    46081 atgcacaaaa aatacatgaa tagactatgg tcactagaag caatattata taatgaatag
    46141 tactcattag ttgattcagt ttggaggttt tagcatgcag cagcaagtcg caataacaga
    46201 aacagtttta cgggacggtc atcaaagttt gatggcaacg cgtttatcta ttgaggatat
    46261 gcttcctgtc cttaccatct tagacaagat tggttattat tccctagagt gttggggagg
    46321 agcaaccttt gatgcctgta ttcgtttttt gaacgaagac ccttgggaaa gactgcgcac
    46381 gttaaaaaaa ggcttaccta atacccattt acaaatgtta ttaagaggtc aaaacctttt
    46441 aggctaccgt cattatgcag atgacatcgt tgacaaattc attagtttat cagctcaaaa
    46501 tgggattgat gttttccgca tttttgatgc cctaaatgac ccacgaaata tccagcaagc
    46561 cttaagagct gtgaaaaaga cgggtaaaga ggctcaactg tgtattgcct atacaactag
    46621 cccagtgcac acgcttaact attacctttc tttagtgaaa gaattggttg agatgggagc
    46681 tgattctatc tgcatcaaag atatggctgg tattctaact cccaaagcgg ctaaagagtt
    46741 ggtatctggt atcaaagcca tgactaactt acctcttatt gtgcataccc atgcaactag
    46801 tggcatttct cagatgacct atctagcagc agtagaagct ggtgctgata gaattgatac
    46861 tgctttgtca ccttttagcg aaggcacttc acaacctgct acagaatcca tgtatttagc
    46921 cttaaaagaa gcaggttatg atatcacatt agatgaaacg ctactggaac aggctgctaa
    46981 tcaccttcga caagtccgtc aaaagtactt agcagatggc attctggatc ccagtcttct
    47041 ctttccagac ccaaggacac tacaatacca agttcctgga ggcatgttat ctaatatgct
    47101 atctcagctg aaacaagcca atgccgaatc aaaattagaa gaagttttag cagaagttcc
    47161 tcgggtaaga aaagacttgg gttatcctcc cttagtaaca ccgcttagcc aaatggtcgg
    47221 gactcaagct gctatgaatg tgattttagg aaaaccttac cagatggtgt ctaaggaaat
    47281 taaacaatac ttggcaggcg actatggcaa aacaccagca ccagtcaacg aagacttaaa
    47341 acgaagtcaa attggctcag ctcctgtcac cacaaatcgt cctgcagatc aactaagtcc
    47401 tgaattcgag gtgttaaaag cagaagtagc agatttagcc caaacggacg aagatgtgct
    47461 gacttatgcc ctcttcccaa gcgtagcaaa accgttttta acaaccaaat accaaactga
    47521 tgacgtcatt aaagtgactg cctttatcaa agcataatag gctatcttaa tcagatagaa
    47581 acaaaaatat ggagatcaaa tgacctattc ctttattgat atcttacaag ttaccttagt
    47641 atccttgttc ttagtgttaa cctgtttaac agggattatg ggattaatga tgctaagtgg
    47701 taaattattg tcacaagaaa aaaaaactct ctctcaacaa gcttccagca ttcctcaaga
    47761 gcaagaagct gacaagttga gtggagaagc tctcgaaact cttttagcca aagacgaatt
    47821 ggctagaatt gctgttatga ctagtcttgc ttatgctagc caagaagagt caggaaaacg
    47881 gtttgaagtt attgccgtgg aaaggaaatc ctaatgaaaa gatatgaagt gactgtcaat
    47941 ggacaggttt atgaagtgag tttacgtgaa ctagctgatg gagaaactgt tgaagttagc
    48001 cagccagcag cacccgctac tgagaaagaa atgaatgcca acgctgctgg cggtggcatt
    48061 caggtaaagg ctccaatgtc tggaacaatc ttgtctatct ttgctacaga aggaaaagct
    48121 gttaaaaaag gagaagctgt tctggtctta gaggccatga aaatggagaa tgaaattcta
    48181 gcacctgcag atggtctggt ttcaaaaatt catgttgtgg ctaaccaaac ggtcgagtct
    48241 gaacaagttt tgatttcatt ctaggaggaa accatgctag acgtactcaa tcaaatggtc
    48301 caatcgtcag gattggctca tctaactgtt aataatctta tcatgatttg cttggcctgt
    48361 ttctttttat accttggtat caaaaaggaa tatgagcctt accttatggt accaatcgcc
    48421 tttgggattt tactcgttaa tttgcctatg gcgggattga tggaccaccc tgccaatggt
    48481 aatcctggtg gccttcttta ttacctatat aagggaacta gcctagggat ttacccacct
    48541 ttaatttttc tttgtttggg ggcatcaact gactttggtc ccttgattgc caatcctaaa
    48601 accattttac taggaggcgc agcacaagtt gggattttct tagccttttt ccttgctatt
    48661 atgttaggca tgacacctca agaagcggct tctgtcggga ttattggtgg tgccgatgga
    48721 ccaacagcta tttatgtgac gacaaagttg gcgcctgatt tactctctac tatcgcccta
    48781 gcagcttatt cttacatggc tctggtacct attattcaac ctcctatcat taaactcttg
    48841 actaccaagg cggaacgcca agtgaaaatg actcaagcaa gaactgtttc acaaaaagaa
    48901 aaaatcattt tcccgattat ggtaacaatc tttgtcagcc ttttggttcc aagtgctaca
    48961 accttggttg gctgtttgat gctgggaaat ctggtcagag aaattaaaat tgttcctaaa
    49021 attgtagata atctccaaca agtggttatg ttttgcatta cgatcatttt agggttaacc
    49081 gttggtgcta aggccaatgg agatctcttt ttatcagcca caaccttgaa aattattgcc
    49141 cttgggctaa tcgcctttgc tgctgggaca gcagggggtg tcttgatggg gaaggtcatg
    49201 tactatttat ctggtaacaa agtgaaccct atgataggag cagcaggtgt ttcagctgtt
    49261 ccgatggcag cgcgagtggt ccaaaaggtc ggacaagaag aagatccaag taatttctta
    49321 ctcatgcacg ccatggggcc caatgtagct ggcgttattg gctcagccat tgcctcaggt
    49381 gccttgctgg ccttctttgg ctaattgtga aaaaggatta gtaaattaat cttaataaat
    49441 cattatcagg agttggaagc aatctagctc cttttttagt agaaagctcg agtgataaac
    49501 tattccaaaa taattataaa aaaagactgt cctgattgta cgaactatat cagttgactt
    49561 ttatagtcta gctgaaatag cagtgcaaaa ctaagacact cgttttaaag tagtttttct
    49621 aaaaaagcaa aataaaaggt cagagccaat aaatctgccg cgcccccagg gcttaaatgc
    49681 tgattaatga ggcattgatt gtaggaggac aaagccaatc ttaggtcagt tgttgataaa
    49741 tcttgttgca gaagtagtcg catatctgcc ttaacgcctt tccatgcttc aatccctcca
    49801 cgatgaatca gatttccatc ttcaacaata gacatcaaat aaacaagaag acgaagctga
    49861 ctggtttcgg ggtcattttg acttatcatc tgacgaaagt agggcaaggc atggtctgtt
    49921 aaggtcgtga atccctcgct tgcctcaccc cgaggtcctt tgatgccata agttacaaag
    49981 agttgctccc cataagtgaa ctctttttta gtgttcaaat gaccaaggtc tgtttgaatc
    50041 aaatgtgccg tcataggttt tactaaacga cagatagcta gagtatcttc cttgctaaaa
    50101 caccctaaat cagtcattaa gtgaggtgtt cttgctagat aggccccagt tgcaccaaga
    50161 agtaaagcca tggaaaaatt caagccttta tgagtgttaa ttccctgagt agcacaaaac
    50221 atggtttcct cggccttttg acctagttgt ctaagacggt taaacagaag aagtggctct
    50281 tcttttgcat aagcaaaacc tgtttcgata taagcctgaa aaaaaggaga gagtgctatc
    50341 atactgtcga taaaggtcat aaaggacata tcatcatggg caccgttatc aaatcgatca
    50401 actaaaccag gttttggaga tagtgagact tcataaagca aagcttttaa agccagttga
    50461 ctaatacttg ttagaactgc cttagtcatt ttgctcaggc ctcatttctt ttaagataaa
    50521 ttcaagtgag ctattcaagt gttcatgtgt aatcaacgta atttgctcat gatctttgtt
    50581 cttcatacct cggtaaatca tccagtgttc agatagagct cgtttacggc gttcaactga
    50641 agaaatcgaa atttttctaa agtagaccaa ataagcttgc aattctgtca caatttcttt
    50701 taagcggacc atttggctat agctgtaaat caaattgtta aaggcattaa aattatccaa
    50761 aatacgattg gtgtcatcct ctgcgataaa ggtttcacag tcttccaaca agttatgcat
    50821 gactttaaaa tcttcttctg tcattaaatg catcgcttgc accgttgcga gagtctctag
    50881 agcttttcga atttcaaaaa tttcacaggc atccttgata ctaactcctt tgacaataat
    50941 gcctttttta ggaatgtgct ctacaaggtg ttcttcagac aataatccca aagcgtagcg
    51001 aataggtgtc ctgctaatat taagcgcaat ggaaaactct ttttcattaa tgcggcttcc
    51061 aacaggaatt tgtcgcaaaa taatggtctt tttaagagcg ttataaaagg ctattttcaa
    51121 agggatattt cttgataggt caagattttg tttaacggct tcgataatag gattcatgtc
    51181 atctccttaa tgctagtgtc ctcactttat tatacttaaa tttgtgaaac attccaatag
    51241 gactagatga gttctgaaaa attaaagcca tgctcacaaa aggacatgac tttaatcatc
    51301 tcataaggaa taaggtagta gtgttatcgt tggtttattg tggaatgtaa agtggcattt
    51361 gtcccatggc aataatggtt accacaaaga taacaaagat gataagggca tatttagcag
    51421 cctctttttg ccattccccc atgtcaagac ctgtcaagcg aagaagaaga taaatgaagg
    51481 caactaatgg actaagtaag tggaaggctt gtcccatgag ggaagcaagt gccatagcca
    51541 tgttactgaa accatattca gcaccagctt ctgcaagaac aggcaagata ccatagtaaa
    51601 aaccatcatt ggagataaag aaggtaccag gtgcagaaac taaggcaata acgagccccc
    51661 agaaacctgc cagttgtttt ggaataatgg ttgcaaaact ttgtgcaaga gcgctagcca
    51721 taccagaacc ttggaaaaga cccataaaga taccagcagc aaagacgaga ataaccactt
    51781 gaaccgcatc accagcatta tcaccaatgc gtttcgattg atctttaagc actgggtaat
    51841 tgaccatcaa ggcgatacaa gttcccaccg caaaaagaag aagcggtgcc atagcaatag
    51901 atttgttgaa agagccagca actaaccaag tgattaatcc aatggttagg atagcattga
    51961 aaacaaagtt tttaggacga cgaataaaaa gggtatctgg gtcagtaatg tctgtgagtt
    52021 gacgcatgtc ttcttcagac aagtcaataa caccaagtct tgcacgttct ttacgcccca
    52081 tgcttggagc aacccaacaa atcacataaa gaagagataa aatcataccc ggtgcaagat
    52141 agccaagaat ttcaggaccg acaccaagaa cagacatcgc acgagcagta gggccacccc
    52201 atggcagtaa gttcataata gtattttgaa gaataatcaa gacacctagg ttcatgattt
    52261 tcatgtccaa ttttttatag ataggtaaga aagcagagca acaaattaaa gtagtggttg
    52321 ttccatcacc attaagagat actgcggcag caacgacagc tgttgcgata agcaccttca
    52381 ttggatcacc tttagcaaag cgaatcatct tttcagtaat cggatcaaac aatcctgcat
    52441 ctaacatgac agagaagaac aaaatggcaa atagcaacat gatacctgtt ttagcagtat
    52501 tgttgatacc atacataacc attggtccga tagctgttag gtctttagca attccaccgt
    52561 caccaacaaa ggcaacaaat ttggcatctg cattgaagtc agctgaacca gtcagtataa
    52621 cagcaattgt catgattaat ggaatcatga ccaaagcagt aaaaggggtc atttttttct
    52681 tcattaccac gtacataaag acaataatca tggcataagc cagcattgtt aataacatca
    52741 ttgttatctc ctttttcaag ttatgatttc agtatagatg aaagcgctta taaaataaat
    52801 acttctttgt gcagaaagac acaaaaaaaa caatttgaaa attaattttg aaaaccattt
    52861 tt
//
LOCUS       DATTYN010000012        47332 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.12, whole genome shotgun sequence.
ACCESSION   DATTYN010000012 DATTYN010000000
VERSION     DATTYN010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47332
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.12"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            435..673
                     /locus_tag="VB649_000871"
                     /pseudo
     CDS             435..673
                     /locus_tag="VB649_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560448.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            694..783
                     /locus_tag="VB649_000872"
     CDS             694..783
                     /locus_tag="VB649_000872"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP1669832.1"
                     /translation="MIIDYCNNKRIKIKLKGLSPLQYKTKSFT"
     gene            complement(821..1744)
                     /locus_tag="VB649_000873"
     CDS             complement(821..1744)
                     /locus_tag="VB649_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669833.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFIKKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSSGQILYDGKVINGRKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEEERKEKIKNMMAEVGLLSEHLTRYPHEFSGGQRQRIG
                     IARALVMNPEFVIADEPISALDVSVRAQVLNLLKRMQAEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFNNPIHPYTQSLLSAVPIPDPILERQKELVVYHPDQHD
                     YTLDKPSMVEIKPNHFVWANQAEIEKYQKEL"
     gene            complement(1737..2807)
                     /locus_tag="VB649_000874"
     CDS             complement(1737..2807)
                     /locus_tag="VB649_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669834.1"
                     /translation="MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFV
                     GESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQELTDLKTNKEWAKIRGSKIATIFQ
                     DPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
                     SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIVEFGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAI
                     PGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAKTWLLHPEAPKVQKP
                     EVIQDLHQKILRKMSQQEEGNV"
     gene            complement(2816..3742)
                     /locus_tag="VB649_000875"
     CDS             complement(2816..3742)
                     /locus_tag="VB649_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009569326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669835.1"
                     /translation="MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTV
                     FMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKRYIWPNAEYWFGTDKNGQSLFDG
                     VWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
                     LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKN
                     LLPQLVSVIMTMLSQMLPVYVSSEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYL
                     FWIPLVTLILVSLPLYIVGQNLADASDPRSHR"
     gene            complement(3742..5244)
                     /locus_tag="VB649_000876"
     CDS             complement(3742..5244)
                     /locus_tag="VB649_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669836.1"
                     /translation="MKKYILNRIMRSLVSVVLVTALTYTIVYTLVPTSLIFKQDPNYN
                     KMTTTPDKKVAYENLTFQRMGYVNYFSSKELKDNASKVDSSVTTEATSANKAIYEKYI
                     DSLGNGWQLKRFPTSKQFYAIRNIPIYERVWNFFSNLVVIDHPWKIQDKDNPKLARYI
                     RLEKDKSVGWSLVGSGTKHKYLLYTNGKFPYLHQNFVTLNLGTSYPTYSNIPVLQVIS
                     QGQGRTALQDVTFPSGVTKKSSVDIYSRSYKNPKSLDDITKVNYGKGDSYTKTINNYV
                     DPSMIHNSFVIGFFGVMFSYIVGLPLGLFMARFKNTYFDRFSTATMTFMLALPSIAVI
                     YVVRFLGGMAGLPDSFPMLGASDPKSYILPALILGILNIPTTVIWFRRYLVDLQASDW
                     VRFARSKGLSESEIYRGHLFKNAMVPIVSGVPASIILAIGGATLTETVFAFPGMGKML
                     IDSIKSANNSMIVGLTFIFTVLSIVSLLLGDIVMTLVDPRIKLSTKKGGK"
     gene            complement(5309..7279)
                     /locus_tag="VB649_000877"
     CDS             complement(5309..7279)
                     /locus_tag="VB649_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP1669837.1"
                     /translation="MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVN
                     DPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLVPSLAKDWKVSKDGLTYTYTLRD
                     GVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
                     GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGA
                     YFLSAFTSKSSMEFHKNENYWDAKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARL
                     YPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKKDPAQQDAGKKALNN
                     KDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKL
                     GDEWKDVNLADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQE
                     AQSFKQSVEASLGKENVIVNVLETETSTHEAQGFYAETPEQQDYDIISSWWGPDYQDP
                     RTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDNDARYKA
                     YAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVT
                     AKQYENAKEKWMKAKAKSNAKYAEKLADHVEK"
     gene            7610..8842
                     /locus_tag="VB649_000878"
     CDS             7610..8842
                     /locus_tag="VB649_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP1669838.1"
                     /translation="MIKRLISLVVIALFFAASTVSGEEYSVTAKHAIAVDLESGKVLY
                     EKDAKEVVPVASVSKLLTTYLVYKEVSKGKLNWDSPVTISNYPYELTTNYTISNVPLD
                     KRKYTVKELLSALVVNNANSPAIALAEKIGGTEPKFVDKMKKQLRQWGISDAKVVNST
                     GLTNHFLGANTYPNTEPDDENCFCATDLAIIARHLLLEFPEVLKLSSKSSTIFDGQTI
                     YSYNYMLKGMPCYREGVDGLFVGYSKKAGASFVATSVENQMRVITVVLNADQSHEDDL
                     AIFKTTNQLLQYLLINFQKVQLIENNKPVKTLSVLDSPEKTVKLVAQNSLFFIKPIHT
                     KTKNTVHITKKSSTMIAPLSKGQVLGRATLQDKHLIGQGYLDTPPSINLILQKNISKS
                     FFLKVWWNRFVRYVNTSL"
     gene            9010..10191
                     /locus_tag="VB649_000879"
     CDS             9010..10191
                     /locus_tag="VB649_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP1669839.1"
                     /translation="MTKRIILTIFTFICFSMMPLVHAEDVMDITRQAGYTVSEVNRPK
                     SSIVVDANSSDILWQDNIDIPRDPASMSKMFTLYILFEELAKGKITMDTTITATPTDQ
                     AIANIYEISNNNIVAGVAYPIRDLITMTAVPSSNAATVMIANYLSNNDASAFIDRINA
                     TAKQLGMTNTHFSNASGAAAQAFQGYYNPTKYDLSASNITTARDLSKLLYAFLKKYPE
                     IISFTNKSVVHTMVGTPYEEEFHTYNHSLPDNQFGMKGVDGLKTGSSPSAAFNAMITA
                     KRGKTRLITIVMGVGDWSDQNGEFYRHPFVNALTEKGFKDSKTLSKKARQKLEKLVPQ
                     TKKETSPKQQHFKATKKQSYLERVEDFMNHNHTFLLICLAIFIITILLLSLVVFAMGR
                     Q"
     gene            complement(10343..11761)
                     /gene="sufB"
                     /locus_tag="VB649_000880"
     CDS             complement(10343..11761)
                     /gene="sufB"
                     /locus_tag="VB649_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEP1669840.1"
                     /translation="MSDINEKVEPKPIDLGDYQFGFHDDVEPIYSTGKGLSEAVVREL
                     SAAKNEPEWMLEFRLKSLETFNKMPMQTWGADLSDINFDDIIYYQKASDKPARSWDDV
                     PEKIKETFDRIGIPEAERAYLAGASAQYESEVVYHNMKGEFEKLGIIFTDTDSALKEY
                     PDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALTDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANAGQHQDT
                     GAKMIHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKQSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLISYEMEGSVG"
     gene            complement(11754..12233)
                     /locus_tag="VB649_000881"
     CDS             complement(11754..12233)
                     /locus_tag="VB649_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEP1669841.1"
                     /translation="MALSKLNHLYMAVVADHSKRPHHHGQLDGVEAVQLNNPTCGDVI
                     SLTVKFDEDKIEDIAFAGNGCTISTASSSMMTDAVIGKSKEEALALADIFSEMVQGQE
                     NPAQKELGEAELLAGVAKFPQRIKCSTLAWNALKEAIKRSANAQHLTDQNVKEGKNV"
     gene            complement(12220..13446)
                     /locus_tag="VB649_000882"
     CDS             complement(12220..13446)
                     /locus_tag="VB649_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP1669842.1"
                     /translation="MLDAKDIKQDFQILNQQVNDEPLVYLDNAATTQKPALVLEALQS
                     YYQEDNANVHRGVHTLAERATHKYEASRQQVADFIHAKSSKEVLFTRGTTTSLNWVAR
                     FAEQVLTPEDEVLISIMEHHANIIPWQQACQKTGARLVYVYLKDGQLDMDDLANKLTT
                     KTRFVSLVHVSNVLGCINPIKEIAKLAHAKGAYLVVDGAQSVPHLAIDVQDLDCDFFA
                     FSAHKMLGPTGLGVLYGKEELLNQVEPLEFGGEMINFVYEQEATWKELPWKFEAGTPH
                     IAGAIGLSAAISYLQRLGMADIHAHEAELIAYVLPKLEAIEGLTIYGPSQPSARSGLI
                     SFNLDDLHPHDLATALDYEGVAVRAGHHCAQPLLSYLGVPATVRASFYIYNTKADCDR
                     LVEAILKAKEFFNGTL"
     gene            complement(13477..14739)
                     /gene="sufD"
                     /locus_tag="VB649_000883"
     CDS             complement(13477..14739)
                     /gene="sufD"
                     /locus_tag="VB649_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEP1669843.1"
                     /translation="MTKEKLVAFSQAHAEPAWLQERRLAALEAIPELELPTIERVKFH
                     RWNLGDGTLTENESLASVPDFIAIGDNPKLVQVGTQTVLEQLPMALIDKGVVFSDFYT
                     ALEEIPEVIEAHFGQALAFDEDKLAAYHTAYFNSAAVLYVPDHLEITTPIEAIFLQDS
                     DSDVPFNKHVLVIAGKESKFTYLERFESIGNATQKISANISVEVIAQAGSQIKFSAID
                     RLGPSVTTYISRRGRLEKDANIDWALAVMNEGNVIADFDSDLIGQGSQADLKVVAASS
                     GRQVQGIDTRVTNYGQRTVGHILQHGVILERGTLTFNGIGHILKGAKGADAQQESRVL
                     MLSDQARADANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVIAEIPIPSVRQEIIKVLDEKLLNR"
     gene            complement(14834..15604)
                     /gene="sufC"
                     /locus_tag="VB649_000884"
     CDS             complement(14834..15604)
                     /gene="sufC"
                     /locus_tag="VB649_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEP1669844.1"
                     /translation="MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKST
                     LSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKTDEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES"
     gene            complement(15726..16895)
                     /locus_tag="VB649_000885"
     CDS             complement(15726..16895)
                     /locus_tag="VB649_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEP1669845.1"
                     /translation="MFSFTIDYVLVLIGALLMSLFLTPLVRFLAFRVGAVDNPNARRV
                     NKVPMPTSGGLAIFMSFLVASLGLIPIASKGAMFFGQTYFSYILPVVIGATVITLTGF
                     LDDLYELSPKLKMFGILIGAVIVWAFTDFKFDSFKIPFGGPLLVFGPFLTLFLTVLWI
                     VSITNAINLIDGLDGLVSGVSIISLVTMAIVSYFFLPQKDFFLTLTILVLIAAIAGFF
                     PYNYHPAMIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGQKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGITMLFSLISLLLNVSSRIGGV
                     LLMLGLLFGLEVFIEGLETWGEKRTPLFNLLKFIGNSDYRQAMLLKWKEKKDLKH"
     gene            complement(16902..17663)
                     /gene="mecA"
                     /locus_tag="VB649_000886"
     CDS             complement(16902..17663)
                     /gene="mecA"
                     /locus_tag="VB649_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEP1669846.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSV
                     MDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEINKDINLEDLAEFGDMSQMTPED
                     FFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
                     YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLI
                     EHANPGSKTRAYLQEHGLQLMLDGAVEQLQKIELG"
     gene            complement(17809..18648)
                     /locus_tag="VB649_000887"
     CDS             complement(17809..18648)
                     /locus_tag="VB649_000887"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEP1669847.1"
                     /translation="MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKA
                     FIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIA
                     VPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGC
                     FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGH
                     HLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFK
                     FVF"
     gene            complement(18714..20639)
                     /locus_tag="VB649_000888"
                     /pseudo
     CDS             complement(18714..20639)
                     /locus_tag="VB649_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407295.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
     gene            20837..22405
                     /locus_tag="VB649_000889"
     CDS             20837..22405
                     /locus_tag="VB649_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEP1669848.1"
                     /translation="MKKLILSCLVALALLFGGMSRAQANQYLRVGMEAAYAPFNWTQD
                     DASNGAVPIEGTSQYANGYDVQVAKKIAKAMNKELLVVKTSWTGLIPALTSGKIDMIA
                     AGMSPTKERRNEISFSNSYYTSQPVLVVTANGKYADATSLKDFSGAKVTAQQGVWHVN
                     LLTQLKGAKLQTPMGDFSQMRQALTSGVIDAYISERPEAMTAEAADSRLKMITLKKGF
                     AVAESDAAIAVGMKKNDDRMATVNQVLEGFSQTDRMALMDDMVTKQPVEKKAEDAKAS
                     FLGQMWAIFKGNWKQFLRGTGMTLLISMVGTITGLFIGLLIGIFRTAPKAKHKVAALG
                     QKLFGWLLTIYIEIFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRKIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQIQIAEVSNV"
     gene            22398..23138
                     /locus_tag="VB649_000890"
     CDS             22398..23138
                     /locus_tag="VB649_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEP1669849.1"
                     /translation="MSNSIIEIKNLKKSYGSNEVLKDISLSVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGQILFHGEDVLAEHYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRDRAQAEQIAKENLNAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVGEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRIIFMDKGL
                     ITEEGSPQQIFENPTQDRTKEFLQRFLK"
     gene            23281..23397
                     /locus_tag="VB649_000891"
     CDS             23281..23397
                     /locus_tag="VB649_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEP1669850.1"
                     /translation="MAEKTDLSSAYRRLKSPNIKTRKRALKIIHEYKRYGKK"
     gene            complement(23621..24631)
                     /gene="gap"
                     /locus_tag="VB649_000892"
     CDS             complement(23621..24631)
                     /gene="gap"
                     /locus_tag="VB649_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEP1669851.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNIEGVEVTRINDLTDPNMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAK
                     KEAAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGIQKGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTED
                     PIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            complement(24979..27057)
                     /gene="fusA"
                     /locus_tag="VB649_000893"
     CDS             complement(24979..27057)
                     /gene="fusA"
                     /locus_tag="VB649_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEP1669852.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            complement(27424..27894)
                     /gene="rpsG"
                     /locus_tag="VB649_000894"
     CDS             complement(27424..27894)
                     /gene="rpsG"
                     /locus_tag="VB649_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEP1669853.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVY
                     DAFNAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            complement(27915..28328)
                     /gene="rpsL"
                     /locus_tag="VB649_000895"
     CDS             complement(27915..28328)
                     /gene="rpsL"
                     /locus_tag="VB649_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEP1669854.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            complement(28536..31157)
                     /locus_tag="VB649_000896"
     CDS             complement(28536..31157)
                     /locus_tag="VB649_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEP1669855.1"
                     /translation="MDLEQTKPNQVKQKIALTSTIALLSASVGVSHQVKADDRVSGET
                     KASNTHDDSLPKPETIQEAKATIDAVEKTLSQQKAELTELATALTKTTAEINHLKEQQ
                     DNEQKALTSAQEIYTNTLASSEETLLAQGAEHQRELTATETELHNAQADQHSKETALS
                     EQKASISAETTRAQDLVEQVKTSEQNIAKLNAMISNPDAITKAAQTANYNTKALSSEL
                     EKAKADLENQKAKVKKQLTEELAAQKAALAEKEAELSRLKSSAPSTQDSIVGNNTMKA
                     PQGYPLEELKKLEASGYIGSASYNNYYKEHADQIIAKASPGNQLNQYQDIPADRNRFV
                     DPDNLTPEVQNELAQFAAHMINSVRRQLGLPPVTVTAGSQEFARLLSTSYKKTHGNTR
                     PSFVYGQPGVSGHYGVGPHDKTIIEDSAGASGLIRNDDNMYENIGAFNDVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAINFLRVDKRNPNAPVYLGFSTSNVGSLNEHFVMFP
                     ESNIANHQRFNKTPIKAVGSTKDYAQRVGTVSDTIAAIKGKVSSLENRLSAIHQEADI
                     MAAQAKVSQLQGKLASTLKQSDSLNLQVRQLNDTKGSLRTELLAAKAKQAQLEATRDQ
                     SLAKLASLKAALHQTEALAEQAAARVTALVAKKAHLQYLRDFKLNPNRLQVIRERIDN
                     TKQDLAKTTSSLLNAQEALAALQAKQSSLEATIATTEHQLTLLKTLANEKEYRHLDED
                     IATVPDLQVAPPLTGVKPLSYSKVDTTPLVQEMVKETKQLLEASARLAAENTSLVAEA
                     LVGQTSEMVASNAIVSKITSSITQPSSKTSYGSGSSTTSNLISDVDESTQRALKAGVV
                     MLAAVGLTGFRFRKESK"
     gene            complement(31148..31987)
                     /gene="purR"
                     /locus_tag="VB649_000897"
     CDS             complement(31148..31987)
                     /gene="purR"
                     /locus_tag="VB649_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEP1669856.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEEANIGDIDTLTGASGGVIFTPSISETEARTIVEDLCQRLSESDRILPGGY
                     IYLSDLLSTPKILQNIGRIIANAFKGEKIDAVMTVATKGVPLANAVANILSVPFVIVR
                     RDLKITEGSTVSVNYASASSDRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMISL
                     LTEFDSTLVGVAVFAENAQSEREQMTFKSLLKVSEIDVKNNNVVVEVGNIFDKWKKER
                     EWT"
     gene            complement(32254..33192)
                     /locus_tag="VB649_000898"
     CDS             complement(32254..33192)
                     /locus_tag="VB649_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEP1669857.1"
                     /translation="MKINQMKKDQLFEGFYLIKSAEVRKTRAGKDFISLTFQDDTGEI
                     SGNLWDAQPYNVEEFTAGKVVFMKGRREVYNGTPQVNQITLRNVRPGEPNDPKDFKEK
                     APVSVTEVRDYLEQMLFKIENATWQRIVRALYRKYDKEFYTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPDLNKSLLFAGIMLHDLAKVIELTGPDNTEYTVRGNLIGHIS
                     LINEEITKVISELQIDDTKEEVIVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMTTALSRVSEGEMTNRIFAMDNRSFYKPNY"
     gene            complement(33182..34453)
                     /locus_tag="VB649_000899"
     CDS             complement(33182..34453)
                     /locus_tag="VB649_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEP1669858.1"
                     /translation="MDLILFLLVLVLLGLGAYLLFKVNGLQHQLAQTLEGNADNLSDQ
                     MTYQLDTANKQQLLELTQLMNRQQADLYQQLTDIRDVLHRSLSDSRDRSDKRLEKINQ
                     QVNQSLKNMQESNEKRLEKMRQIVEEKLEETLKNRLHASFDSVSKQLESVNKGLGEMR
                     SVAQDVGTLNKVLSNTKTRGILGELQLGQIIEDIMTSSQYEREFVTVSGSSERVEYAI
                     KLPGNGQGGYIYLPIDSKFPLEDYYRLEDAYEVGDKLAIEASRKALLAAIKRFAKDIH
                     KKYLNPPETTNFGVMFLPTEGLYSEVVRNAAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNIQKNADDISKILGNVKLEFDKFGGLLAKAQKQMNTANNTLDQLISTRTNAI
                     VRALNTVETYQDQATKSLLNMPLLEEENNEN"
     gene            complement(34455..35087)
                     /locus_tag="VB649_000900"
     CDS             complement(34455..35087)
                     /locus_tag="VB649_000900"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEP1669859.1"
                     /translation="MSKVALFAGGDLSYISRDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSVSQKAFTDIKEKAELFITAHPEKNDTDTELALKEVFARFPEAEVTIFGAFGGRM
                     DHLLSNIFLPSDPGIAPFMAQIALRDQQNMITYRPAGQHLIHQEEGMTYVAFMAEGEA
                     DLTITGAKFELTQDNFFKKKIYSSNAFIHQPITVSLPSGYLIIIQSKDWS"
     gene            complement(35080..35742)
                     /locus_tag="VB649_000901"
     CDS             complement(35080..35742)
                     /locus_tag="VB649_000901"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEP1669860.1"
                     /translation="MSTLKIAPSILAADYANFASELVRIEETDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVDPERYVEAFAQAGADIMTIHTESTRHIHGAL
                     QKIKAAGMKAGVVINPGTPATALEPLLDLVDQVLIMTVNPGFGGQAFIPECLEKVATV
                     AKWRDEKGLSFDIEVDGGVDNKTIRACYEAGANVFVAGSYLFKASDLVSQVQTLRTAL
                     NV"
     gene            complement(35752..36624)
                     /gene="rsgA"
                     /locus_tag="VB649_000902"
     CDS             complement(35752..36624)
                     /gene="rsgA"
                     /locus_tag="VB649_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEP1669861.1"
                     /translation="MQGKIIKSLAGFYYVESEGQVYQTRARGNFRKRGETPYVGDIVD
                     FSAEDNSEGYILAIHPRKNSLVRPPIVNIDQAVVIMSAKEPEFNSNLLDRFLILLEHK
                     AIHPVVYISKMDLLDSPEEIKAIGRQYQAIGYDFVTSLEELLPLLADKITVFMGQTGV
                     GKSTLLNRIAPELALETGEISDSLGRGRHTTRAVSFYNTHGGKIADTPGFSSLDYDIA
                     NAEDLNEAFPELRRLSHECKFRSCTHTHEPKCAVKAALETGELWPVRYEHYLQFLSEI
                     ENRRETYKKVIKRK"
     gene            complement(37049..37921)
                     /gene="rsmA"
                     /locus_tag="VB649_000903"
     CDS             complement(37049..37921)
                     /gene="rsmA"
                     /locus_tag="VB649_000903"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEP1669862.1"
                     /translation="MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVED
                     EDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKAKLEKGLALADIKPSIRGEALSIQ
                     DFGKLADALKEVGL"
     gene            complement(38035..38625)
                     /gene="rnmV"
                     /locus_tag="VB649_000904"
     CDS             complement(38035..38625)
                     /gene="rnmV"
                     /locus_tag="VB649_000904"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEP1669863.1"
                     /translation="MQRGYSSLTEKINIQEVLVVEGKDDTANLRRFYEVDTYETRGSA
                     ITEEDLERINRLNDLRGVIVLTDPDYNGERIRKLIMAAVPTARHAFLNRNEAVPSSKS
                     KGRSLGVEHARFEDLQKALAHVTQQYDDESYFDIRQTDLIRLGLLMASDSRKRREYLG
                     EKLRIGYANGKQLLKRLELFGITLAEVEEVMETYEE"
     gene            complement(38597..39388)
                     /locus_tag="VB649_000905"
     CDS             complement(38597..39388)
                     /locus_tag="VB649_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEP1669864.1"
                     /translation="MTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVV
                     GFDQATISGALTLANKYANIYATIGWHPTEAGSYSEAVEESIVSQLSHPKVIALGEIG
                     LDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVIKAAGVGPRGGIM
                     HSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVETDAPYLTPV
                     PKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD"
     gene            39673..40503
                     /locus_tag="VB649_000906"
     CDS             39673..40503
                     /locus_tag="VB649_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEP1669865.1"
                     /translation="MPKNHRLITKIEASLEHMTSLEKGIAHFFITTDLTPQELTASEI
                     VKRLHISQAALTRFAKKCGFTGYRAFAFDYLHSLQESQETFQSIHLELTKRVLMDYDA
                     LINKTYELVNEEKLLNLAKLIDSSERVYFFGKGSSGLVAREMKLRFMRLGLICDAYSD
                     TDGFTWANSLVNENCLVFGFSLSGKTNSVITALHQASQRGAKTILLTTDNQTEFDDSL
                     DIIPVSSTHQLHYGNRVSPQFPLLIMMDIIYAYVLAIDKPHKEKIFKNTIIDKENNDL
                     "
     gene            complement(40614..41552)
                     /locus_tag="VB649_000907"
     CDS             complement(40614..41552)
                     /locus_tag="VB649_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEP1669866.1"
                     /translation="MKYYLAIDIGGTAIKYGLLSEDGELLEKVEMATEAYKGGPSILE
                     KVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETFGL
                     PCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
                     YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVD
                     YLGQGIANICYVVNPNVVVLGGGIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASH
                     GNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS"
     gene            complement(41573..42490)
                     /locus_tag="VB649_000908"
     CDS             complement(41573..42490)
                     /locus_tag="VB649_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEP1669867.1"
                     /translation="MTDLTKYQGIIPAFYACYDDQGAISPERVRALTQYYIDKGVQGL
                     YINGSSGECIYQSVFDRQLVLENVMAVAKGKLTIINHVACNNTKDSIELAAHSERLGV
                     DAIAAIPPIYFRLPEYAVADYWNAISSAAPHTDFIIYNIPQLAGVALTPSLYKTMLAN
                     KRVIGVKNSSMPVQDIQTFCAIGGDDHIVFNGPDEQFLGGRLMGAAAGIGGTYGAMPE
                     LFLRLNQLIADKDLEKAKALQYTINEIIGVLVSAHGNMYGVIKEVLRINEGLDIGSVR
                     SPLSELVEEDMVICQRAASLISQAKETFC"
     gene            complement(42502..43164)
                     /locus_tag="VB649_000909"
     CDS             complement(42502..43164)
                     /locus_tag="VB649_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEP1669868.1"
                     /translation="MTSKKQGLLHSLFKLDSKWMRASAALFDLLVFNLLFVLSCLPLL
                     TIGVAKMALYASLLDWREGQVSQLVTTYSSHFKHYFKSGMRLGLIELLMMSICVLDLF
                     LIRNQSGLVFQGFKVLCIAVLFLVVILFLYAYPQAVKRDLSLSTLFKRSFLLAGLFFP
                     WSFAFLALICLTIFSLQLSLLTLFGGVSLLAIIGISSLTYLYLIIMESLLRRFPLNND
                     IE"
     gene            complement(43321..44151)
                     /locus_tag="VB649_000910"
     CDS             complement(43321..44151)
                     /locus_tag="VB649_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEP1669869.1"
                     /translation="MTKKKLTASDILTAVMLCVLTILFIFPFYWIMTGAFKAQADTIM
                     IPPQWWPKAPTIENFKALVVQNPALKWLWNSVFISVATMFLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIVKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRENLTISLGVATMQAEMATNYGLIMAGAAMAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            complement(44164..45051)
                     /locus_tag="VB649_000911"
     CDS             complement(44164..45051)
                     /locus_tag="VB649_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEP1669870.1"
                     /translation="MNVNKLKMRETLISYAFLAPVLVFFVIFVLIPMIMGFVTSFFNY
                     SMTDFTFVGFANYARMFQDPIFMKSLINTLIIVIGSVPVVVFFSLFVAAKTYDKNVVA
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYAHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWNIKWPSLLPTTL
                     YIAVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAV
                     MIAIISFAQFKILGNDVEY"
     gene            complement(45155..46474)
                     /locus_tag="VB649_000912"
     CDS             complement(45155..46474)
                     /locus_tag="VB649_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEP1669871.1"
                     /translation="MNMKKLASLAMLGASVLGLAACGGKSQKEASASKSDAAKTEITW
                     WAFPVFTQEKAEDGVGTYEKKLIAAFEKTNPEIKVKLETIDFTSGPEKITTAIEAGTA
                     PDVLFDAPGRIIQYGKNGKLADLNDLFTEEFTKDVNNDKLIQASKAGDTAYMYPISSA
                     PFYMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPR
                     AFFANLYSSHITDDKVTKYTTDDANSIKAMTKISNWIKDGLMMNGSQYDGSADIQNFA
                     NGQTSFTILWAPAQPGIQAKLLEASKVDYLEIPFPSDDGKPELEYLVNGFAVFNNKDE
                     QKVAASKTFIQFIADDKEWGPKNVVRTGAFPVRTSYGDLYKDKRMEKIAEWTKFYSPY
                     YNTIDGFAEMRTLWFPMVQAISNGDEKPEDALKAFTEKANKTIKKTQ"
     gene            complement(46523..47227)
                     /locus_tag="VB649_000913"
     CDS             complement(46523..47227)
                     /locus_tag="VB649_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEP1669872.1"
                     /translation="MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLLAKA
                     AQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMAEVDQLAALNI
                     AVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTT
                     LSGYTPYSRQEAGPDVALIEALCKAGVAVIAEGKIHSPEEAKKINDLGVAGIVVGGAI
                     TRPKEIAERFIEALKS"
BASE COUNT        14227 a        10033 c         8722 g        14350 t
ORIGIN      
        1 atagcctgtc aactactttt tcatcttttt tcaataagtg tgttacaaga acctctctga
       61 cagctttatt agtatacgat atctttactg tcattgtcaa ctcttttttt actttttttg
      121 tactttttta tttgcccgcg ttgtaaaatg aagtgcaaca aaaaagagga aaagccttga
      181 accacacccc aaacgttaga caaaaaaatc taacgttcgg ggtatttttt atgaaattaa
      241 gtgatgaagg tacgaaatag acatcgttaa gaaagaaaaa aatacctact atccaccaga
      301 gataaagcag gaaataatgg ataacgtttt gatagaaggc ccgccacaat accaagtatc
      361 acttgtttat ggcttgttac atgcaggaac tctcccaagt tgaatagcac aatataagaa
      421 aaacagttat actgttgaga aaacaagagc aagaccatca caaacaggac gtaaaccaaa
      481 tgaaacctga agaaatgact aaattagagc ggcttcaaga agaaaatgaa tatctcagaa
      541 ctgaggttgc ttacttaaaa aaccgaggga actccgtttg aaagaagcat ctctgcaaag
      601 aagaagacaa aaaaccatta taaagaatgg acaaagacga gttctgatta gattttcttt
      661 taagaacggc taaattgact cgttctacct actattatca tcgattattg caacaataaa
      721 cgtatcaaaa taaaactaaa aggacttagt cctctacaat acaaaactaa atcctttact
      781 taaaatagag tagccaactt ttggggtcag tgcatctctt ttacaattct ttttgatatt
      841 tttcaatttc tgcttggttt gcccaaacaa agtgatttgg tttgatttca accattgatg
      901 gcttatctaa tgtataatca tgctggtctg gatgatagac aacaagttct ttttgacgct
      961 ctaaaattgg atctgggata ggcacggctg ataacaaaga ttgggtgtag ggatgaattg
     1021 ggttattaaa cagttcttct gtttctgcaa cttctacaat aaccccttta tggataaccg
     1081 caatacgatc tgaaataaag cgaacgactg aaagatcatg ggcaatgaag agataagtca
     1141 aacctttttc ggcttgcatc cgtttgagaa ggtttaaaac ctgtgcgcga acggaaacgt
     1201 ccaaagctga aatcggttca tcagcaataa cgaattcagg gttcattact agggctctag
     1261 cgataccgat ccgctgacgt tgacctcctg aaaattcatg agggtagcgc gtcaaatgct
     1321 ctgatagcaa accaacttcg gccatcatgt tcttaatttt ttctttacgt tcttcctctg
     1381 ttttaaacag attaaagtta taaagacctt ctgaaatgat gtagtcaacg gttgcccgtt
     1441 cattcaaact agcagcggga tcttggaaaa tcatttgaat tttacgaatg agctcattgg
     1501 cttctgattt tgattttctg ccattaatta ctttcccatc gtataaaatt tgacctgagc
     1561 tagtatcgtt caaaccaata atagcacgac caattgttgt tttaccactc ccagattctc
     1621 caactaaaga aaaggtttct ccttttttaa taaagaaatt agcattttta actgcaacaa
     1681 attttttctt tccttctccg aaggaaattt ctaggtcttt tacttcgact aatttctcag
     1741 acatttcctt cctcctgttg tgacattttc cttaagattt tttgatgcaa atcttgaatg
     1801 acttctggtt tttgaacttt tggagcctct gggtgtaaaa gccatgtttt ggcccaatga
     1861 gtctcagata cgttaatcgc cggaggtgct ttttcaaagt ctaaaaccat agcatattct
     1921 gagcgaagtg caaaggcatc tccgataatt ggtgaataaa gtgatggagg cgttcctgga
     1981 atagcgtaaa gttcaccaga ttcatctgcc aactgcggta agctagacag caaactccat
     2041 gtataggggt gtcttggatc atagaaaatc tcttcgactg ttccaaattc aacaatttct
     2101 cctgcataca tgacagccac tttatctgca atgcttgcca caacacctaa atcgtgcgta
     2161 ataaagataa tggtgaaatg atattctcgt tgaagcgact tcaataactc aacgatttga
     2221 gcttgaatag tcacatcaag ggctgttgtt ggctcatcac agataagaat atctgggcga
     2281 caagctaaag caatagcgat aacaatacgt tgacgcattc ctcctgaata ctcaaatggg
     2341 taatcttcaa agcgtttttt ggcatttggg atacccactt tattcatgta atcaagggcc
     2401 atttctttag ctttggcatg acttactttt tggtgcttaa taatcacttc tgtgatttgg
     2461 ctaccgatag ttttaatggg actaagactg gtcattgggt cttggaaaat cgttgcgatt
     2521 tttgagccgc gaatctttgc ccactcttta tttgttttta aatctgtcaa ttcttgccca
     2581 cgatagacaa ttgaaccatt agcaatgcgt ccattagact ccaacatccc tgtaaaggtc
     2641 tttgttaaaa cagatttacc tgagcctgat tcccctacaa aagcaaggac ttctccttca
     2701 acaagttcca gtgagacgtt acggatagct gttaaaacac gatcacgcac atcaaattct
     2761 accaccacat ctttggcagt taagattaca ttattttctt ttgtcatttt aactcctatc
     2821 tatgtgaacg tgggtcactg gcatcagcca agttttgtcc gacaatgtat agtggtaacg
     2881 atactaaaat caatgttact aagggaatcc aaaagaggta ggcatttgtt gttaagttgc
     2941 ttgaataatt agcaatcaaa cgtcctaaac ttggagtggt ggttggtaaa ccaatcccaa
     3001 agaaggataa gaaggcctca gaagatacat aaactggtag catttgtgac aacatagtca
     3061 tgataactga aaccaattga ggcaggaggt tcttaacagc aatcttgtac atgggtgttc
     3121 ccaaagtttg actagcaagg ttgtattcta aatcacggta acgcaagatt tgaacacgga
     3181 tggagtaggc gacaccaatc catccagtga tacagaaagc tagaatcaaa ttccaaaatc
     3241 ctgcacctaa tgaataggtc aaaacaatga taataagcat agaagggata tttgagataa
     3301 tgttataaat ttcaatcata actttatcaa atgctttaga aactccccat atggctccta
     3361 acactacccc aatggtgata ttaattagtg tcgctataac tgagattaaa atagaattac
     3421 gtgccccata ccaaacacca tcaaacagag attgcccatt tttgtcggtt ccaaaccagt
     3481 actctgcatt tggccaaata taacgctttg aaaagtcatt gatattacta acgtcattaa
     3541 agtcgtagtt ggcaaacatt ggataaataa agctcatcat caagactgtc actaaaatca
     3601 cgagcataaa gactgtagat tttttagaaa aaaactgacg aaacactgat ttccagtaag
     3661 aataagcagg ggtatcaatc acttcggagg cttcactatc gcgctcaaca aatcgaaatt
     3721 tagatttatc aatcgattcc attacttacc tccttttttt gttgacaatt taatacgtgg
     3781 atcgacaagg gtcatgacaa tatctcctag taaaagtgaa acaattgaca agacagtgaa
     3841 gataaaggtt aatccaacaa tcatagaatt gttagcagat ttaatagaat caattaacat
     3901 tttacccata cccgggaagg caaagacagt ctctgttaag gttgcaccac caatagcaag
     3961 gataatactt gcaggaaccc ctgacacaat tgggaccatg gcatttttga agagatgccc
     4021 tctgtaaatt tcagattctg ataatccttt tgaacgcgca aaacgtaccc aatcactggc
     4081 ctgaaggtca acaagatagc gacggaacca gataaccgta gttggaatat ttaaaattcc
     4141 taaaataagg gctggtaaaa tataagattt aggatcagat gcccctagca ttgggaaact
     4201 atctggtaaa ccagccatgc cacctaggaa gcgaacaaca tagataacag caatacttgg
     4261 taaagcaagc atgaaggtca tggtcgctgt tgagaaacgg tcaaaatagg tatttttaaa
     4321 ccgagccata aataaaccaa gaggcaaacc aacgatatag gaaaacataa caccaaaaaa
     4381 accaattaca aaagaattgt gaatcattga tgggtcgaca taattattga tggttttagt
     4441 gtaggaatct cccttaccat agtttacctt ggtgatatca tccaatgatt ttggattttt
     4501 gtagctacgg ctatagatat ccactgacga tttcttagtg acacctgatg ggaaggtcac
     4561 atcttgaaga gctgttcgtc cttgcccttg tgaaataacc tgaagaacag gaatattgct
     4621 gtatgttggg taagatgttc ctaagtttag ggtaacaaag ttttggtgaa gataaggaaa
     4681 ttttccgtta gtgtagagga gatatttatg ttttgtcccc gaaccaacaa gtgaccagcc
     4741 aactgattta tctttttcta gacgaatata cctagctaat tttggattgt ctttatcctg
     4801 aatcttccaa gggtgatcaa taacaactag atttgagaaa aagttccaaa cacgttcgta
     4861 aataggaata ttgcgaattg cataaaactg tttgctagtg gggaagcgtt ttagctgcca
     4921 gccattgcca agagaatcaa tatacttctc atagatagct ttgttagcac tagttgcttc
     4981 tgtcgttaca ctactatcta ctttagaagc attatctttt aattctttgc ttgaaaaata
     5041 attgacataa cccatacgtt gaaaagttag attttcatac gctacttttt tatctggtgt
     5101 tgttgtcatt ttattataat tagggtcttg tttaaagata aggctggtag gtactagagt
     5161 atatacgatg gtgtatgtta aagccgttac caaaactacc gacactaacg atcgcatgat
     5221 acggtttaaa atgtattttt tcatagttat cctcaatagt tcaaaagaac ttcctcacat
     5281 aaacgagaaa gttcttttga acatcgtttt atttttcaac gtgatcagct aacttctcag
     5341 catattttgc atttgactta gcctttgctt tcatccattt ttcttttgca ttttcgtatt
     5401 gttttgctgt gacaggtttg tcttgaagtt tcattccttt atatgctaga ggacctttag
     5461 accctgccca agagaagccc ccgctaaatg gaacggcttt agtaactcgt ggagtgccac
     5521 ccaatgccac aactggaata tctacggcac tatctgtaag gtaggcttgt gcttttgcgt
     5581 aagctttata gcgcgcatcg ttgtcgtctg taattgctgc tgcttcatca aggagagttt
     5641 ggtaagtatc aaggcctgca gctgccacaa catccttatt ttgacctgct ttgattccaa
     5701 gtttttggat aacagatcca ccacctactg gactcatgat gtcaaggtag gtccgtggat
     5761 cttggtagtc tggtccccac catgatgaaa tgatatcgta gtcttgttgt tctggggtct
     5821 cagcatagaa gccttgggct tcgtgagttg atgtttctgt ttcaagaaca ttgacaatga
     5881 cattttcttt accaagagat gcttcaacag attgtttgaa agactgagct tcctgaacag
     5941 ttgctgcgtt tgcttggtca acagggtaat ctaattgaac tgggaaggtt acaccttcag
     6001 ctgtcaaagc ttctttggct tttgcaaact cagcttttgc tttttcagga ttatagaaac
     6061 catcttgagc atcagctaag ttaacgtctt tccattcatc accaagtttt gccatttcct
     6121 tttcaacttc tgaaccaaaa tcactttctc caatggtcac aaatgttggt ggcacaagca
     6181 tgttacgtaa ggcttttgtt ttggcatctt gacctgcagt ttgtgcttgg aatgacgctc
     6241 ggtcaaaagc aaactgaata gcttgacgaa aatccttgtt gttaagagct ttcttaccgg
     6301 catcttgttg tgcagggtct ttcttagtgt ttttgaaaga agtacggttc aaattccatg
     6361 ttaaatgacg gatatctcca gtcaacattc cgtaagtaat gttatcagca tagtttttct
     6421 tagctgattt gtaggtaggg tcatttgggt aaagtcgtgc aacgctgaac tcacccttgt
     6481 caaagttctt gtagaacgaa cctgggtctg aaccatctga gtaagtcaat ttaacagatt
     6541 ctatcccaac attcttagca tcccagtagt tttcattttt atggaattcc atagatgatt
     6601 ttgaggtgaa ggcgctcaag aagtaagcac cattaacaag gattgatgat ggatcggttg
     6661 taccaaaatc tttacctttt gacttcaaaa atttcgcatt aactgggaaa agcacactat
     6721 aagttgtttt tgaattccag tagctttcag gcttgttcaa agtatactga acagttttat
     6781 cgtcaagggc tttgacacca acttctttaa aatctacttc accattttgg taagccttta
     6841 agttttttat tgaatcttca acaacgtaaa gagcatctga tttatcgtca accgcgtgct
     6901 tcaaaccagt cacaaaatct tctgctgtta ctggggcata ttcttcacca tcagccgtat
     6961 accaagagac accatcgcga agagtataag tataagtcag accgtctttt gaaaccttcc
     7021 aatctttagc aagtgatggt actaaattac catactcatc gttttccaaa agaccatcaa
     7081 ccatttgtgt tatcacatca gttgttccac cgccattagt caaaatataa tccaatgatt
     7141 ttggatcgtt aacaaaaacg tacttgtagg tttttgtagc ttctgagcca cctgaagcat
     7201 ttttattacc acaagctgcc aaagcggata ctgacaagat cgcaacactt acagctgcca
     7261 accatttact tttcttcata aaagtcaccc ctaaacttta tttttcattt tttggcaatt
     7321 gctaaatgaa attggttaat tgaagacatt atatcataaa actttcttaa agaaaataat
     7381 gaaatgaaaa attatctgaa tatttcgtag aattttcttt attttataca tttatctata
     7441 tgaaagcgtt acactccttt tttaatgagg tttcaattag tttaataaag attgtcattc
     7501 tctcatggta gcgttttatt acatcactac tcttgtgagg taagtcatta ccttagacaa
     7561 aaatatggta taattaaaaa aataatactt gagtaaggat aatctataaa tgatcaaacg
     7621 attaatttcc ctagtggtca tcgccttatt ttttgcagca agcactgtta gcggtgaaga
     7681 gtattcggta actgctaagc atgcgattgc cgttgacctt gaaagtggca aagttttata
     7741 cgaaaaagat gctaaagaag ttgtcccagt cgcctcagtc agtaagctct tgacaaccta
     7801 tctggtttac aaagaagttt ctaagggcaa gctaaattgg gatagtcctg taactatttc
     7861 taactaccct tatgaactca ctacaaacta tactattagt aacgttcctc ttgataagag
     7921 gaaatatacc gttaaagaac ttttaagtgc gttagttgtt aataacgcca atagccccgc
     7981 tattgcttta gctgaaaaaa taggcggaac cgaacccaaa tttgttgaca aaatgaaaaa
     8041 acaattaaga caatggggca tttccgatgc aaaggtcgtc aattcaactg gcttaactaa
     8101 ccatttttta ggagctaata cttatcctaa tacagaacca gatgatgaaa attgtttttg
     8161 cgccactgat ttagctatta ttgccaggca tctcttatta gaatttccag aagtactgaa
     8221 attatctagc aaatcctcca ctatttttga tggacaaacc atttacagtt ataattacat
     8281 gcttaaaggc atgccttgtt atcgagaagg cgtggatggt ctttttgttg gttattctaa
     8341 aaaagccggt gcttcttttg tagctactag tgtcgaaaat caaatgaggg ttattacagt
     8401 agttttaaat gctgatcaaa gccacgagga tgatttagct atatttaaaa caaccaatca
     8461 attgttgcag taccttttaa ttaattttca aaaagtccag ttaattgaaa ataataaacc
     8521 agtaaaaacg ttatctgtct tagacagtcc tgaaaaaact gtcaaacttg tagcccaaaa
     8581 tagtttattt tttatcaaac caatacatac aaagaccaaa aataccgtcc atattactaa
     8641 gaaatcatcc acaatgatcg cacctctatc aaagggacaa gtcttaggta gagcaaccct
     8701 tcaagataaa catcttattg gacaaggtta tctggatact cctccttcta tcaatcttat
     8761 ccttcaaaaa aacatttcta aaagtttctt tttaaaggtc tggtggaacc gttttgtgag
     8821 gtatgtcaat acctctttat agaataacac aatgcttttt gtatgacatt gactgacaga
     8881 gtacttctgc agtctttttc atttttattt aagcaaacta ggctaatcct aacaattttt
     8941 caaaaaaact tcacattgta ttagcaaagt gatatactga aaatgcatta catttaaagg
     9001 agtcggaaat tgaccaaaag aattatacta actattttta cctttatttg cttttcgatg
     9061 atgcctcttg tccacgccga agatgtcatg gatattacaa ggcaagcagg ctacacagtt
     9121 agtgaggtta atcgaccaaa atcttctatt gtcgttgatg caaatagttc agatattctt
     9181 tggcaagata atattgatat tcctagggat cctgctagta tgtctaagat gtttacgctt
     9241 tacattttat ttgaagagct cgctaaggga aaaattacga tggacactac tattacggca
     9301 actccaaccg atcaagctat cgctaacatt tatgagatta gcaataataa tatcgtcgct
     9361 ggagtagctt atcctattcg tgatcttatt actatgacag ctgtgccttc atcaaatgca
     9421 gcaactgtta tgattgccaa ttatttatca aacaatgatg cttctgcgtt tatcgatcgt
     9481 attaatgcca cagccaaaca attaggcatg actaacactc atttttcaaa cgctagtggt
     9541 gcagcagcac aagcttttca aggttattat aatcctacta aatatgattt atctgcttca
     9601 aatattacga ccgctcgaga tttgtccaag ttactctatg ccttcttaaa aaaataccct
     9661 gaaattatct cctttacaaa taaatctgtt gtgcacacta tggtaggaac gccatatgaa
     9721 gaagaatttc acacctataa ccactctctc ccagataatc aatttggtat gaaaggagtt
     9781 gatggattaa aaacaggttc tagtcccagc gctgctttta acgccatgat aactgccaaa
     9841 agaggcaaaa ctcgactcat tactattgtc atgggggtcg gagattggtc agatcaaaac
     9901 ggagagtttt atagacatcc tttcgttaat gccttgactg agaaagggtt taaagatagt
     9961 aagaccttat ccaaaaaagc acgccaaaaa ctcgaaaaat tagtgccaca aaccaaaaaa
    10021 gaaacatcac ctaaacagca gcacttcaaa gccactaaaa agcaatcgta cttggaaaga
    10081 gtcgaagatt ttatgaatca caaccatact ttcttgctta tttgcttagc tatctttata
    10141 attactatcc ttttactaag cctcgttgtc tttgcaatgg gacgccaata atgaattatc
    10201 aaaaacctct gtcaaagcac agaggttttt gatatgttat cttacgtgtt taaggcaact
    10261 aaaaactaac cacttggggt tagtactaca actcataaaa ttctatctca aagatctttc
    10321 agatggataa gagaaaatgc aattaaccga cagaaccttc catctcatag gaaatcaatc
    10381 gattgagttc gaccgcgtat tccattggca attctttggt aaaaggctcc acaaatccca
    10441 tgacaatcat ctctgtggct tcgctttctg ataagccacg gctcatgaga tagtagagtt
    10501 gttcttcaga aatcttagac actttggctt catgttctaa cgccacctgt gaattatgaa
    10561 tttcgttaaa tgggatcgta tctgatttag aaatatcgtc catcaaaata gtatcacatt
    10621 caatatggga aacggatttt ttagattgct tgttaaaggt cacttggcca cgataatcta
    10681 ctttaccacc agacttggca attgattttg acacaattga tgatgatgta tgtggagcat
    10741 tgtgaatcat tttagcccct gtatcttggt gttggcctgc gttagcaaag gcaatagaca
    10801 gcatggtgcc acgtgcacct ggcccatcaa gataaacaga agggtacttc atggtggttt
    10861 tagctcctag attgccatca atccattcca ctgttgcatc cgtaagggcg cgtgcacgtt
    10921 ttgttactag attatacaca ttgtctgacc agttttgaat ggtggtataa cgcatgtatg
    10981 caccgtcaag cgcaaagatt tcaacgatag cagcatgtaa gctgttactt gaataagtgg
    11041 gagctgtaca tccttcaaca taatgaacac ttgctccttc atcaacaata atcaatgtcc
    11101 gctcaaattg accagtattt tcattgttaa tgcggaaata agtttgcaaa ggaatatcta
    11161 ccttgacccc tttaggaaca taaataaagg taccaccaga ccaaactgct gaattgaggg
    11221 ctgctaattt gttgtctgtt ggcggaacca gtttggcaaa gtattgtttg aacaaatcag
    11281 gatattcttt gagggcggaa tcggtatctg taaagataat ccctagcttt tcaaattcac
    11341 ccttcatgtt atggtaaacc acttctgact catactgagc tgatgctcca gcaagataag
    11401 cacgttctgc ttctggaatt ccaatacgat caaaggtttc ttttattttt tctggaacat
    11461 catcccaaga acgagctggc ttatcagatg ctttttgata gtaaatgata tcatcaaagt
    11521 taatatctga taagtctgct ccccaggttt gcatcggcat tttattaaag gtttccaagg
    11581 attttaaacg aaactccaac atccactcag gttcattttt ggcagctgat agttcgcgaa
    11641 ctactgcctc actcaatcct tttcctgtag aataaatggg ctctacatca tcgtgaaatc
    11701 caaattggta gtcccctaag tcaattggct ttggctctac tttctcattt atatcagaca
    11761 tttttccctt cctttacatt ttggtccgtg aggtgctgag cattggcact tcgtttaatg
    11821 gcttccttga gagcattcca agctagggta gagcatttga tacgctgtgg aaattttgca
    11881 actcctgcca acaattctgc ttcacctagc tctttttgag caggattttc ctgtccttgt
    11941 accatctctg aaaaaatatc agctaacgcg agtgcttctt ctttactttt accaataaca
    12001 gcatctgtca tcatgcttga tgaagctgtg gaaatggtac agccgttgcc tgcaaaagca
    12061 atatcttcaa ttttatcttc gtcaaactta acggtcaaag aaatcacatc accacaagtc
    12121 ggattattca gttgaacagc ctctacgcca tctagttgcc catgatgatg tggacgtttc
    12181 gaatggtccg ctaccacagc catgtataga tggttcagtt tagagagtgc cattgaaaaa
    12241 ctcctttgct tttagaattg cttcgactaa acggtcacaa tctgccttgg tgttatagat
    12301 ataaaaactt gctctaacag ttgctggtac acctaaataa ctaagaagag gttgggcgca
    12361 gtggtgtcct gctcttactg caacaccttc atagtccaag gctgttgcca agtcatgagg
    12421 atgcaaatca tccagattaa aagaaatcag accagatctt gcactaggct ggcttggtcc
    12481 atatatggta agcccctcaa tagcttctaa tttcggcaaa acataggcta ttagttctgc
    12541 ttcatgcgca tgtatatcag ccatgcctag tctctgaagg taagaaatgg ctgcgcttag
    12601 cccaatagca ccagctatgt gaggtgttcc tgcttcaaac ttccagggca attctttcca
    12661 agtggcctct tgttcgtaaa caaaattaat catttctccg ccaaattcaa gaggctccac
    12721 ttgattcaaa agctcttctt tgccgtaaag aacacccaaa cctgttggcc ccaacatctt
    12781 atgagctgaa aaagcaaaga aatcacaatc caagtcttga acatcaatag ccaaatgtgg
    12841 aaccgactgg gcaccgtcaa caacaaggta ggctccttta gcatgtgcca gcttggcaat
    12901 ttctttaatg ggattgatgc aaccaagaac attggagaca tgtactaggc taacaaaacg
    12961 tgtttttgtc gtcaatttgt ttgccaaatc gtccatgtca agttggccat cttttaaata
    13021 aacatagact aaccttgctc ctgttttttg acaggcttgt tgccaaggaa tgatattggc
    13081 atgatgctcc ataatcgaaa tcaacacctc atcttctggc gtcaagacct gctctgcaaa
    13141 ccgagcaacc caattcaaac tggttgttgt tcctctggta aagagcactt ccttacttga
    13201 tttagcatga ataaagtcag caacctgctg gcgactggcc tcatatttgt gcgttgcacg
    13261 ttcagctaag gtatgaactc ctcggtggac attagcatta tcttcttgat aataggattg
    13321 caaagcctca agaacaagcg ccggtttttg tgtggtggcg gcattatcca aataaacaag
    13381 gggttcatca ttgacttgtt gatttaagat ttgaaagtct tgtttgatgt cttttgcgtc
    13441 tagcaatact aacctctttc tttttggcag taggtcttaa cgattaagca atttctcatc
    13501 taaaacctta ataatctctt ggcggactga tggaatagga atttcagcga taaccgctcc
    13561 taggaatcct ctaataacca atcgttctgc tgtttcttga tccagtcctc gactcatcaa
    13621 gtaatacata tcttcagggt caacctgacc gatagaagct gcatgacctg ctgttacttc
    13681 attttcatca attaagagga ttggattggc atcggctctt gcttggtcag aaagcatcaa
    13741 aacacggctt tcttgttgag catcagctcc cttagcgcct tttagaatat gaccaatccc
    13801 gttaaacgtt aaggtgccac gttccaaaat cacaccatgc tgtaaaatat gaccgaccgt
    13861 acgttgacca tagttggtca cgcgcgtgtc aataccttgt acctgacgac cacttgaggc
    13921 tgcaacaact ttcaaatcag cttgtgagcc ctgaccaatc aaatcactgt caaaatcagc
    13981 aatgacattg ccttcattca tcacagctaa ggcccaatca atgttggcat ccttctctaa
    14041 acgtcctcga cggctaatat aggttgtcac tgaaggacct aagcggtcga tagccgagaa
    14101 tttaatctgg ctgcctgctt gagcaatcac ttctacactg atattagcgc tgatcttttg
    14161 agtggcattg ccaatagatt caaaacgctc taaataggtg aacttacttt cttttcctgc
    14221 aatcactaga acatgcttgt taaaaggaac gtcactgtca ctatcttgta agaaaatagc
    14281 ttcaatagga gttgtgattt ccaagtgatc aggaacgtag agcacggctg cgctattaaa
    14341 ataagcagtg tggtaggcag ctagtttgtc ttcatcaaaa gctaatgcct gaccaaaatg
    14401 agcttcaatt acttctggga tttcctcaag cgccgtataa aaatcactga aaacaactcc
    14461 cttgtcaatt aacgccattg gtaactgttc taagactgtt tgcgtgccta cctgaacaag
    14521 ctttgggtta tctccaatag ctataaaatc tggaacacta gctagacttt cattttctgt
    14581 taaggtacca tctcctagat tccaacggtg aaatttaacc ctttcgatgg ttggtaactc
    14641 taattctggt atggcttcta atgccgctaa acgccgttct tgcagccaag caggctcagc
    14701 gtgggcttgc gaaaaagcca ctagtttttc ttttgtcatc tgtcaatcct ttgtctctgg
    14761 tttttaaatt ggctgggtat atagaacatc acctagcttt ttgtagaaag ctaaagtaat
    14821 tgtctccaaa aacttaactt tcttccttat actcgattcc cagatcctgt gcaatacctg
    14881 cgtagccttc tttttcaaga cgagtagcca aggcagcatc accagataag acaatacgac
    14941 catccatcat aacatgaact aggtctgggg taatgtaatt caacaaacgt tgatagtggg
    15001 tgataatcat agctccaaag tctttcccac gcatctcatt aaccccttta gagactactt
    15061 ttagggcatc aatatcaaga ccagaatcaa tttcatctag caaagcaaat ttaggctcta
    15121 acatgagcaa ttgaagaatt tcattgcgtt ttttctcccc accagaaaaa ccttcattga
    15181 ggtaacgctc tgccatctct tctttcatac ctaacaaagc cattttctca tcaagtttgg
    15241 tgataaaatc tcgcacggaa atcttatcct catctgtctt accggcattc attgctgcac
    15301 gcataaattc agcgttggta atccctggaa tttctgaagg gtattgcatg gcgagaaaaa
    15361 gtcccagtct cgcacgctca tcaacttcta gatcgagaat attgaccccg tcaagcaaaa
    15421 tctgcccttg ggtcacttcg tagttaggat ttcccataat agctgctgaa agggtagact
    15481 ttcctgtccc atttggcccc ataatggcag ctacttcccc agttttaaga gttaggttaa
    15541 cccctttcaa aatctcttta ccttctattg aaacatgtaa attattaatc tcaagaattg
    15601 acatgataca ccccttattt tctctgtcat ctataccatc tcaagaaaag acagtgtcat
    15661 ttgcactgct ttttttataa tggtcactgc atctattata gcaaaaaaag ccttactcgg
    15721 cttttttagt gtttcaaatc cttcttttct ttccatttca gaagcattgc ttgacgataa
    15781 tcactattac caataaactt taacaagtta aacaaaggcg ttcgcttttc accccaggtc
    15841 tccaatcctt caataaaaac ttctaaacca aataaaagtc caagcatcaa gaggacgcca
    15901 ccaattcgac tagaaacatt taaaagtaaa gaaataaggg aaaaaagcat ggtaatacca
    15961 taaactacta agacagctcc tcgatgagta aagcccattg ataagagtcg atgatgcagg
    16021 tgcatcttat ccggctcgta gaatttttga cctgataaac tacgtcgaat aatagccacg
    16081 atggtatcca taatgggtac accaagaata ataacaggtg tcaccacagc cacagccgtt
    16141 gaatttttca atccttgaag agacaaaacc cctatcataa agccaataaa gagggctcct
    16201 gtgtcaccca aataaatcat agctggatgg taattataag gaaaaaatcc tgcaatagca
    16261 gcaatcaaga ccaaaatggt taacgtcaaa aagaaatcct tttgaggtaa aaagaaataa
    16321 gatacaatag ccatggtcac taaactaata atagagaccc cactaaccaa accatccaaa
    16381 ccgtcaatca agttaatagc attagtgatg gaaacaatcc acaggactgt taagaataag
    16441 gttaagaaag gaccaaaaac taacaacggc cctccaaaag gaattttgaa gctatcaaat
    16501 ttaaagtcgg taaaagccca gacaatcact gcaccaatta gaataccaaa catctttaat
    16561 ttaggactta actcatacaa atcatctaaa aaaccagtaa gggtaattac tgtagcacca
    16621 atcacgacag gtaaaatata actgaagtag gtctgaccaa aaaacatggc acctttagaa
    16681 gcaatcggaa taagtcccaa acttgctact aaaaaagaca taaaaatagc taatccacca
    16741 ctggttggca tcggaacctt attgacccgt ctggcattgg gattgtctac tgcacccaca
    16801 cgaaaggcta aaaagcgaac aagaggggtt aagaataagg acattaacaa agcccctatc
    16861 agaacaagga cataatctat tgtgaatgaa aacatactat tttatcccaa ctcaatcttt
    16921 tgtaattgct caacagcacc atcaagcatc aattgtaagc catgctcttg taaataagct
    16981 cttgtttttg atccagggtt tgcatgttca atcaatctcg catacatgac attcgcaaaa
    17041 taagatggtt gttgctgaac atctaataaa atagtcatat ggtagcagtt gctcccctta
    17101 tataactctg aagcttctat cgaaaaatca atcgttttag caaaagccac tgcctctgta
    17161 atcgttgaaa aatccaatac ataatggaca tagtctaaag gttctgactc atgattagtt
    17221 gatggatcag ccgcctcaga ctgattagct agagtggctt caacaacatc ttccattatc
    17281 tcttcaattt tttccaattt ttcatgagct ttgacatctc ccttttcacg catggattgc
    17341 tccaagctct tgaaaaaatc ttccggagtc atttgggaca tatcaccaaa ctctgctaaa
    17401 tcttcaagat taatatcttt atttatctca gatttggtaa caaaaacatc tagacggtcc
    17461 ttgcgtggag tcactcgaaa actaagcata ccactatctt taaaattatc tggaagatca
    17521 agttcgtcca tcacagaata gaaaaactct tctgtttttt cttgaggaat caagaaatct
    17581 ttcaactcca ttcctctttc ttctaaatcg tccatactaa ttgttatttt tagcgttgtc
    17641 tcgctaattt gtttcatttc cattctcaat acctcgcacg cgtagtcatt ttattatact
    17701 agaaatgctg taatttcgca atttatgact aactcctcgt ctacaaaagg aaatttaaaa
    17761 agcgacagtc cccaaggtct gtcgcaacat cctaaacgat atgtaagttt aaaaaacaaa
    17821 tttaaagaag ctataaataa gtaaaaggct tcctaacaca atacggtatt tcccaaaaat
    17881 ggtgaaatcg tgtttcttaa cataatctgt caagaaccta atcgccaata aactaaccac
    17941 aaaagcggtc aagctagcca ctaaaagaat aaggacttgt gcaaaatcaa ggtgatggcc
    18001 atcaaggaaa aatttcacag cctttaatcc actatatcca aacatggtag gaatggccaa
    18061 aaagaaggtg aaatcagcgg ccactgttcg actagttcct aaaataatag ctcctaagat
    18121 ggtagcccct gatcgactag taccaggcac aatacttaag acttgaaaac aaccaatgaa
    18181 gaaagctgtt ttgtaagaca ttctagctaa ctcagtgacg gcaggttctt gttgagcatt
    18241 tcgtttttca atccagataa aggcaatccc gtagacgatt aaagcgatgg caatcggaac
    18301 cataaaataa aaatgtgctt caaaccaatt atcaagagga accgctatta aaatagaagg
    18361 aatacacgca atcaccactt ttagccataa ttgccaggta agctgtactt ctcttgctgt
    18421 tttcccaggt tgaaagggat tgagacgttc aaaataaatc aacataacag cgataatcgc
    18481 ccctaattga ataacgatat taaacatttc tataaaagcc ttatcctgat ttagtcggat
    18541 aaattcctgc accaaaatga ggtgaccagt gcttgaaact ggtaaccatt ctgtgattcc
    18601 ctcaatgatg ccaaagaaaa tggcttttag caattcgata attaacatgt tttctcctta
    18661 ttaaccactc ttattgtgat tttctaaact gtgattaatg ccaagcagct tttttaaaag
    18721 gcaccgccgc cgcctcctcc gccaccgcca gagaagccgc caccaccact aatcccgcct
    18781 ccggaagaga ctgagaaatt tgaggaagtt gtagctgaag acaagctaga cacaaaggtt
    18841 ggtgtcgtag catacattac cattgataat tcacctggtc gaacagcttg gtaaacctca
    18901 ggtaaggcaa tacgatggac tttcaaatag cgttccactt tcttagcgta accaaataag
    18961 gtggcataaa ccaaaacacg gttccaaaca accaaacctt caatagcaac atcctcaaat
    19021 ttgtcaatgt ctcgtatcat gtttttaaag ctctgccatt gatgtaaccg aacacccccc
    19081 tcaggtgttt caatacccaa tttcttgtat tgatctaact tcaggctaat gtaaaagcca
    19141 aggcacatcg ttagcaccat taaagcaagg taaatgaggg ccaacccact ttctttaata
    19201 gccaagtaaa tcaataaacc actatttaga ataagcaaca aacaacctaa tccctggaca
    19261 ctattgcttt ttcgtttctc tgccggggtc atttgacgat aagtatctgg taagtttaac
    19321 tttttgatag tttctaggac attgtttgta atagctgccg acgctttttt catcgcctta
    19381 atcacctgct cagacgattg acggacttct tgctcgagct ttttaccttt gtacgttttc
    19441 tttaattgtt taatggtatc agcatcataa tggtattgac taaacaattg atccaccggc
    19501 aatgtcacct tgtttccaaa agccatatct aagaaggcag cttcctcatc tgtcacacga
    19561 tctaactgac tgatttcaag ataagctttc ccttcttctt tcgttaataa aagcaccttt
    19621 tggtcgatca gatccaacaa ggtagcttga acaagggcct caaaggtcac tcctttaggg
    19681 atcaataatt tctggctttc tgatgctgta ggggataaat aggcaaaact ctgtccataa
    19741 atcgcttgtg tcaacacaag aggcgaaaga tcttcaggga cttcgtaact gtgatctgta
    19801 tggttagcca aatgataacg attgaattgt ttctttaatc ttgtaaactg tattaactgc
    19861 caaagaagaa aacctacctc caccagagga atgactttgc caaatagcag ctgtaacaag
    19921 gcccttcgtc tggaaatctt agtttccaac gctacaattt tattcttttt actcgttgaa
    19981 acatcaactg gctcttttcc caataatgct tttttatccc aataagcatg caattccaat
    20041 tgccctgaga cattcttggc attaatctga tagcgactgt taccttcttt taacacttga
    20101 ggtttctttt ggtaatatcc tctgtgagct catagattag aatcctgaat atcagttggg
    20161 gtagtgacgg tcaaactcac cttttctaat gttttatccc aatcactaat cggtgtccaa
    20221 ttcagctctg ccacgtcttg ataagctgtt aaaaggtggt gcaattgcca gataaccttg
    20281 acgtcaacct tatcaccagc ttggccagca ttataaagtt ttaaacgata gccatctcca
    20341 aggtcactaa actcttgact aacaggtacc tgttgaccat tctgatatac ctcaacttta
    20401 ggcttttggt caatagcaaa gcccgctggc aaatgacctg tccggcccag cgaaatatac
    20461 tggccgttat aagaagtgtc aaattgatag gttacttttt gctcaaaccg agcagtattt
    20521 tcttttgata acagtaactg accttcatag ttggtgatgc tatagtctac atcagctgct
    20581 tttattcgta tccctaaaag actgaagcag agcacaagcg tcatcaaaat ttttttcatg
    20641 gcaacatcct ctttctgccc tcattttacc atattttaag gagatgacaa aacctaaacc
    20701 aagtccttca tcttattttt actcattatt ttgaatattt ttccatattt caacctattc
    20761 actgataata tattgaaata ggatgcaaat tgctgtaaaa taggtctgaa tactattttt
    20821 gaaacaggag acctatatga aaaagctaat ccttagctgt ttggtcgcct tggcccttct
    20881 gtttggagga atgagccggg ctcaagcaaa ccaatattta agagtcggaa tggaagcagc
    20941 ctatgctcct tttaactgga ctcaagatga cgcttcaaac ggggctgtcc ctattgaggg
    21001 aactagccaa tacgccaacg gttacgatgt ccaagtcgct aaaaaaatcg ctaaagctat
    21061 gaacaaagaa ctgttagtcg ttaagacctc ttggaccggt ttaattccag cattaacttc
    21121 tggaaaaatc gatatgatcg ctgctggtat gagtcctacc aaagagcgta gaaacgaaat
    21181 tagcttctca aacagctact acactagcca acctgttcta gtcgtaactg ctaatggcaa
    21241 atatgctgat gcaacaagcc tcaaggattt ttctggagct aaagtaactg cccagcaagg
    21301 cgtttggcat gtcaatctct taactcaact aaaaggtgct aagttacaaa caccaatggg
    21361 agatttctct caaatgcgac aagcccttac ttcgggtgtt atcgatgcct atatttctga
    21421 acgacctgaa gccatgactg ctgaagctgc tgatagccgt ttgaaaatga tcactcttaa
    21481 aaaagggttt gctgttgctg aatcagatgc tgctatcgct gtcggaatga aaaaaaatga
    21541 cgatcgtatg gcaactgtca accaagtgct tgaaggattt tctcaaacgg atcgtatggc
    21601 cctgatggat gatatggtta ccaaacaacc cgtggaaaag aaagccgaag atgctaaagc
    21661 atcatttcta ggccaaatgt gggctatttt taaaggtaac tggaagcaat tcttacgtgg
    21721 aactggaatg acccttctga tttccatggt cggaaccatt acaggtctct ttattggatt
    21781 attaatcggt attttccgta cagctcctaa agctaagcat aaagtagctg ccttgggaca
    21841 aaaactcttt ggttggttac tcactattta tatcgaaatc ttccgtggga cacctatgat
    21901 tgttcaatct atggttatct actacggaac agcgcaagcc tttggtattt cgatcgaccg
    21961 taccctagcg gctattttta tcgtatctat caatacgggt gcctatatga gtgaaattgt
    22021 tcgcggtggt attttcgctg tcgacaaagg tcaattcgaa gcagcaactg ctcttggctt
    22081 tactcacgga caaaccatgc gtaaaatcgt gctaccacaa gttgttcgca acattttacc
    22141 agcaacaggt aatgagtttg tcatcaatat caaagatact tctgtcttga atgttatctc
    22201 tgttgtggaa ctttacttct caggtaatac cgtagccaca caaacctacc aatatttcca
    22261 aacctttacg attatcgcca ttatctactt tgttcttacc ttcacggtga cacgtattct
    22321 tcgttatatt gaacgccgtt tcgatgccga tacttacacc actggagcaa accaaataca
    22381 gattgcggag gtctcaaatg tctaactcaa ttattgaaat caaaaacctc aaaaaatctt
    22441 acggcagcaa tgaagtactc aaagatatct ccctttctgt taacaaggga gaagtgattt
    22501 ccattatcgg ttcttctggt tctggaaaat caaccctcct gcgctcgatc aatcttttgg
    22561 aagagccaag tgccggtcaa atcctctttc atggtgaaga tgtccttgct gaacactaca
    22621 acttgactca ctaccgtgaa aaactaggca tggttttcca atcctttaac ttgtttgaaa
    22681 acctaaatgt attggaaaat gctatcgtcg ctcaaaccac cgtcctcaaa agagaccgtg
    22741 cacaagccga acaaatcgct aaagaaaacc tcaatgcggt tggtatgaca gaacaatact
    22801 ggcaagccaa accaaaacaa ttatcagggg ggcaaaaaca acgggttgcc attgccagag
    22861 ccttatctgt caatccagaa gccatgctct ttgatgaacc aacatcagct cttgatcctg
    22921 aaatggttgg tgaggtcctt aaaaccatgc aagacttggc aaaatcaggg ttgaccatga
    22981 ttattgttac ccatgaaatg gaatttgctc gtgatgtttc tgaccgtatc atcttcatgg
    23041 ataagggatt gattactgaa gaaggaagtc ctcaacaaat tttcgagaat cctacacaag
    23101 atcgtaccaa agaattttta caacgcttct taaaataaga taaaggatcc aactatttct
    23161 atgccagttg ggtctttttt caattcaaaa agaatttgtc ataaaaacac tttaccagtt
    23221 aactatttta tgctatactt atttttgtta acgttaataa tttatattta ggaggataat
    23281 atggcagaaa aaactgactt atcgtcagct tacagaagac tgaaaagtcc caatattaaa
    23341 accagaaaac gtgctctgaa aattattcac gagtacaaac gttacggtaa aaaataggat
    23401 tctattttta tctctccaaa tttaagtcag acaaaaaagg ctaagacacc ccttccatct
    23461 tagccttttt gtatacagtt tattaaggga actattttaa aatatctttt atgctagagt
    23521 ctagaatagt tcaaaacgtt aaaattatac atttaaggta gtgtttaaag tatacgaaaa
    23581 agaactcagc ataaaccaag ctctctttcg ttataactaa ttatttagca atttttgcga
    23641 agtactcaag agtacgtaca agttgagcag tgtaagacat ttcgttgtca taccatgata
    23701 caactttaac caattgtgat ccgtcaactt ccattacttt agtttgagtt gcgtcaaaca
    23761 atgaaccgta tgatacgcct acgatatctg aagaaacgat tggatcttca gtgtaaccga
    23821 agctatcgtt tgaagcagct ttcatagcag cgttgatttc gtcaacagaa acgtttttgt
    23881 caagagttac aaccaactca gttactgatc cagttggaac aggaacacgt tgtgcagcac
    23941 cgtcaagttt accgttaagt tctgggataa caagaccgat agctttagca gcaccagttg
    24001 agttaggaac gatatttgca gcaccagcgc gtgcacgacg aaggtcacca ccacggtgtg
    24061 gtccgtcaag gatcatttgg tcaccagtgt aagcgtggat tgtagtcata agaccttttt
    24121 gaataccgaa tgcatcgtga agagctttag ccataggagc taaacagttt gtagtacatg
    24181 aagcacctga gataactgtt tcagtaccgt caagaatgtc gtggttagtg ttgaaaacaa
    24241 ctgttttaac atcgtttcca ccaggagctg tgataacaac ttttttagca ccgttagcat
    24301 gtaagtgttt ttcagctgct tcttttttag caaagaaacc agttgcttca agaacgattt
    24361 caaccccatc agttgcccag tcgatgtttt ctggatcacg ttcagcagaa actttgatga
    24421 agtttccgtt tacttcaaat ccaccttctt taacttcaac tgttccatca aaacgacctt
    24481 gagttgtatc gtatttcaac aagtgtgcaa gcatatttgg atctgtaagg tcattgatac
    24541 gagttacttc aacaccttcg atgttttgaa tacggcggaa tgcaagacgt ccgatacgac
    24601 cgaaaccgtt aataccaact ttaactacca ttagtgattt cctccttatg aaaatcaaaa
    24661 gaatattatt tagagggaac gctccctacc tattgtgaaa agattaactt acagtcatct
    24721 gcaacaacct ttcaacagaa ctattatata actatttcag aaaaaatgca aataaattag
    24781 ccattttcat aaagggcagc ttctttcttc tagccttcaa aacccaccaa atataggaaa
    24841 gggctttctt ttttctatgt tctattctgt aatttatctt tttattggga aagatttcca
    24901 aaacttcaaa ctgtactata acgttctgtt acactaaaaa agaggttagg atagttatcc
    24961 tcaacctctt agtggtggtt attcaccttt gtttttctta atgatttctt cttgaactga
    25021 cttaggaaca tcttcatagt ggtcaaatac catcatgaat gtaccacgtc cttgagtagc
    25081 agaacgaaga actgttgcat aaccgaacat ttcagcaagt ggaacataag cacgaacgat
    25141 ttggctgtta ccatgtgctt ccataccatc aacgcgtcca cgacgagctg tcacgtgtcc
    25201 cataacgtct ccaagattgt cttctggagc tgtaatcgtt acaagcatca tcggctcaag
    25261 gatagctggt tgtgctgatt tagctgcttc tttaagagca agagatgctg cgatcttgaa
    25321 ggcagtttca gatgagtcga catcgtggta tgaaccatcg taaagtttag ctttaacgtc
    25381 aaccattggg taaccagcaa gaacaccgtt tgccatagat tcgatcaacc ctttttcaac
    25441 agctgggata aattcacgag gaaccacacc accaacgata gcattttcga attcgaaacc
    25501 tttaccttct tcatttggtg taaattcaat ccaaacatca ccgaattgac ctttaccacc
    25561 agattggcgt ttgaagaatc cacgagcttg tgtagaagca cggaatgttt cacggtaaga
    25621 tacttgagga gcaccaacgt tagcttcaac tttgaactca cgtttcatac ggtcaacaag
    25681 gacatcaagg tgaagttcac ccataccagc gataactgtt tcaccagttt caacgtttgt
    25741 ttcaacacgg aatgttggat cttcttcagc aagtttttga agggcaacac ccatcttgtc
    25801 ttggtctgct ttagattttg gctcaaccat caactggata actggttctg gaacttcgat
    25861 tgactcaaga ataacttttg ctttttcatc agtcaatgag tcaccagttg ttgtgtcttt
    25921 caaaccaaca gcggcagcga tgtcaccagc gtaaactgtt tcaatttctt gacggctgtt
    25981 tgcgtgcatt tgaaggatac gtccgatacg ctcacgttta ccttttgatg tgttcataac
    26041 gtaagaaccg ctattaagaa cacctgagta aacacggaag aatgtcaaac gacctacgaa
    26101 tgggtcagtc atgatcttga aggcaagagc tgcaaatggc tcttcatcag atgctggacg
    26161 ttcttcttca gcatctgtat ccgggttaac acctttgatt gcagggatgt caagtgggct
    26221 tggaaggtat gcgataaccg catcaagcat caattgaaca cctttgtttt tgaaggcaga
    26281 accacaaagt actgggaaga attcaacgtt gattgttgct ttacggatac cagcaatcaa
    26341 ttcgtcgtta gtgatttctt caccttcaag gtatttcatc atcaagtctt catcagtttc
    26401 agcaactgct tcgattaatt tttcacggta ttcttgagct tgttctaagt attcttctgg
    26461 aatatcttct tcaagaatat ctgtaccaag gtcgttggta tagatttctg ctttcatctt
    26521 gatcaagtca atgataccac ggaaatcatc ttctgcaccg attggcaatt ggattgggtg
    26581 tgcatttgct tgaagacggt catgaagggt ttgtactgag taaaggaagt cagcaccgat
    26641 tttatccatt ttgttggcga aaacgatacg tggaacaccg tattcagttg cttgacgcca
    26701 aactgtttca gtttgaggct caacacctga ttgtgagtca agaacggtta cagcaccatc
    26761 aagaacacgg agagaacgtt gtacttcgat ggtgaagtcc acgtgtcctg gtgtgtcgat
    26821 gatgttaacg cggtgaccat cccattgagc tgttgtagcg gcagaagtaa tagtgatacc
    26881 acgttcttgc tcttgctcca tccagtccat ttgtgatgcg ccttcgtgtg tttcaccgat
    26941 tttatgaatt ttaccagtgt agtaaaggat acgctctgtt gtagttgttt taccagcatc
    27001 gacgtgagcc atgataccga tattacgagt ttttgcaagt gaaaattcgc gagccatgtg
    27061 tttctcctat ttttttagtt tactctttca ttatagcact atttagcaaa aacggatagg
    27121 caggacctac ccgttatcta aatatttgtt ggtaaagata atacctattg cctttataag
    27181 gcttggtatc ttattcattg aactcaggct aaacgctgtg tgaaaaagat aaactttcct
    27241 agagacaaag gtttcttcgt caaatttcct attttcactt tgcgttctat acgccttcgt
    27301 atcttattaa ttgagttcga gctacaagcc actgacaaaa agataatagt tcctagaaac
    27361 tgaagtttct gcgtcaattt ccctattttg tctagcattt gtttgacgct aaaatatctt
    27421 atattaccaa cggaagtgag caaaggcacg gttagcttca gccattttgt gagtgtcttc
    27481 acgtttcttg actgatgcac ctgtgttgtt tgcagcatcc atgatttctt tagcaagacg
    27541 atctttcata gtgtgttcac cacgagcacg tgatgcgttg accaaccaac gaagtccaag
    27601 tgttgtacga cgttctggac gaacttcaac tgggacttgg tagttagaac caccgacacg
    27661 gcgtgcgcgt acttcaagta caggcatgat gttgtccata gctgtttcaa atacttcaag
    27721 agcgtcattt cctgttgctt ctttgatagc gttgaaagca tcgtaaacga tagtagcagc
    27781 tgtaccacgt ttaccgtcaa gcataacacg gttgataaga cgtgttacga tttttgagtt
    27841 atataatgga tctggtaata cttcgcgttt aggcgcttga tttttacgac tcattttctc
    27901 ttatccccct tctattatcc ttttggacgt ttcgcaccgt atttagaacg gccttgttta
    27961 cggtcagcaa cacctgcagt atcaagtgcg ccacgaacga tatggtaacg tacccctgga
    28021 aggtctttta cacgtccgcc acggataaga acaacgctgt gctcttgcaa gttgtgtccg
    28081 atacctggga tgtaggcagt tacttcgata aggttgctca aacgtacacg agcgaattta
    28141 cgaagggctg agttaggttt tttaggtgtc attgttccaa cacgagtggc aacgccacgt
    28201 ttttgtgggg cagccatttt agtttgaact tttttgtgac tgttgtaacc aatgttcaaa
    28261 gctggtgaat ctgatttttc aattttagat ttacgtggtt tacgtaccaa ctggttaatt
    28321 gtaggcatct acattctcct gtgttttttt atttttggtt gatatagcac ttggtgacag
    28381 cccatatccg gtgcactttt tgcaacaatt gtcagcacgt ctctgtacac ttttgagaga
    28441 ccaaaagtaa aaagtaccgt ctaatataat aacacagacg gtacttcatg tcaaatagaa
    28501 tttttccttt gatgcaattg cttatgacga atgcatcact tagattcctt acggaaccta
    28561 aatcctgtga ggccgacagc tgccaacatg acgactcctg ctttaagagc tctttgagta
    28621 ctttcatcaa catcagaaat gagattgctc gttgtagaag atcctgagcc ataagatgtc
    28681 ttagatgagg gctgagtaat cgaagatgtg attttagaca caatggcatt acttgctacc
    28741 atttcagagg tttggccaac aagcgcttct gctacaagac ttgtattttc agcagctaat
    28801 cttgctgaag cttctaatag ttgtttcgtt tctttaacca tttcttgaac aagcggagta
    28861 gtatctacct tactatatga tagcggtttt acgcccgtaa gaggtggagc tacttgcaaa
    28921 tcaggcacag tagctatatc ttcgtctaag tggcgatatt ccttttcatt agctaaggtt
    28981 ttaagcaaag ttaactggtg ttctgtggta gcaatagtag cttctagact gctttgttta
    29041 gcttgtaagg ctgctaaagc ttcttgtgca tttaacaaag atgaggtagt tttagccaaa
    29101 tcttgcttag tattatcaat gcgctcacgt atcacttgaa ggcggttagg attcaattta
    29161 aagtccctta gatattgcaa atgagctttt ttagccacca gtgctgtcac tctggctgcg
    29221 gcttgctctg ctaaggcttc tgtctggtgc agtgcggctt tcaacgatgc tagcttagcc
    29281 aatgattgat cacgagtagc ttcgagttgt gcttgttttg ctttagctgc tagtaattct
    29341 gttctcaaag aacctttagt atcatttaat tgtctcactt ggaggtttaa gctgtctgac
    29401 tgcttaagtg tgcttgctaa tttaccttga agttgactta ctttagcttg ggctgccata
    29461 atatcagctt cttgatgaat agccgacaaa cgattttcta atgagcttac ttttcctttg
    29521 atcgctgcaa tagtatcaga tacagtgcct actctttggg cataatcttt tgtacttcca
    29581 acggctttta taggggtctt attaaagcgt tgatggttag caatgttaga ctctggaaac
    29641 attacaaagt gttcattcaa agatcctaca ttgctggttg aaaatccaag gtaaacaggc
    29701 gcattagggt tacgtttatc tacacgtaaa aagttaatag catggccata tgtatttccg
    29761 tgtaaatgat ctgtaaagag catatacttg atactgtcat aaataccacg tttaatacca
    29821 ttcacagtat gcacatcgtt aaaagcaccg atattctcgt acatgttatc atcatttcga
    29881 atgagccctg acgctccggc agagtcttca ataatagttt tatcatgagg cccaacacca
    29941 taatgccctg atacccctgg ctgtccgtag acaaatgatg gtcttgtatt accatgagtt
    30001 ttcttatagc tggtactaag taatcttgca aattcttgtg atcctgctgt aacagtaact
    30061 ggtggtagac ctaattgtct tcttacacta ttaatcatgt gagctgcaaa ctgcgctagc
    30121 tcattttgca cttctggtgt caaattatcg ggatcaacaa agcgattacg atctgctgga
    30181 atatcttggt attgatttaa ttgattacct ggactagctt tggcaataat ttgatctgca
    30241 tgctctttgt aataattatt gtaactagct gatccaatat aaccactagc ttctaatttt
    30301 ttaagttctt caagaggata gccttgcggt gctttcatgg tattattacc cacaatgcta
    30361 tcttgagtag acggagctga ggatttaaga cgactaagtt ctgcctcttt ttctgctaga
    30421 gcagctttct gagctgccaa ctcttcagtc aattgctttt taactttagc tttttgattt
    30481 tctaagtcag ctttagcctt ctccaattct gagcttaatg cttttgtatt ataattagcc
    30541 gtttgagctg ctttagtgat agcatcagga ttgctaatca tagcattgag cttagcaata
    30601 ttttgttcag acgttttgac ttgttccact aaatcttgag ctcgagtagt ttctgctgaa
    30661 atgctagctt tttgttctga caatgcagtc tcttttgaat gttgatctgc ttgagcatta
    30721 tgaagctctg tttcagtagc tgttaactct ctttgatgtt cggctccttg ggctaatagc
    30781 gtctcctcac tacttgcaag agtattagtg taaatttctt gtgcagaggt taaagctttt
    30841 tgttcattat cttgctgctc ttttaagtgg ttgatttcag cagtagtttt tgtcaaagcg
    30901 gtagcaagct ctgtcagttc tgctttttgt tgactgagag ttttttcaac tgcatcaata
    30961 gttgcctttg cctcttgaat tgtttctggt tttggtaaac tatcgtcgtg agtattactc
    31021 gccttcgttt ctcctgagac tctatcatct gctttgactt ggtgagatac gcctacactg
    31081 gcactcaata aagcaattgt tgaggttaaa gcaattttct gcttaacttg gtttggcttc
    31141 gtttgttcta agtccattct ctctcctttt tccatttatc gaaaatatta ccaacttcta
    31201 caacaacatt gttgtttttg acatcaatct ctgaaacttt cagcaatgat ttgaaggtca
    31261 tttgctcacg ctctgattga gcgttttctg caaacacagc aacaccaact aaagtgctgt
    31321 caaattctgt caagagactg atcattcctg taatcgtccc cccgcccttc aagaaatcat
    31381 ctacaatcaa tacacgacta ttgggtttca aactacgctt tgacagaaac atcttttcaa
    31441 tacgatcact agaagcactc gcataattga cagacactgt cgatccttct gttatcttta
    31501 aatcacgtct aacaatgaca aaaggaacac ttaaaatatt agccactgca tttgctaaag
    31561 gaactccttt ggttgcaact gtcatcacag cgtcaatctt ttctccttta aaggcattgg
    31621 caataatacg accaatattt tgtaaaattt taggtgtact cagcaagtct gacaaataga
    31681 tatagcctcc aggtaagatg cgatcactct ctgataacct ttgacacagg tcttcaacga
    31741 tggtacgcgc ttctgtttct gaaatactgg gggtaaaaat tacgcctcca cttgctcctg
    31801 taagtgtatc gatatcacca atgttagctt cttcaaaagc tttcttgata atagcgatat
    31861 cttctgagat agaagatttt gcggcctcat atttagttgc aaaggtgttt aaactagtta
    31921 atttatacgg attgttaatc aaataatttg aaatgacaac catacgttca cttcgtctta
    31981 atttcatagt ttccccattt ttatgtactt tttgctatta taccataaag ttaataaaaa
    32041 acgaacattc gattaggaaa atattggttt ttttgttctt attaatatca tgcaagaatt
    32101 caatctaaga taaactaatc aacattccta ctgaaaggac attctactta ataaccataa
    32161 caagagccaa aaacacttat gaaaccatca taagtgttaa gcacatcaaa aatcatcaca
    32221 aaagcaaagg aactattact tgagaaacac tgatcaatag tttggcttat aaaaagaccg
    32281 attatccatg gcaaaaatcc gattggtcat ctcgccctcg ctaacacggc taagagctgt
    32341 tgtcatcatc atcatattag catcaatatt gtcaatcata tgaataattt cagcttccat
    32401 gatgcgtgga cgtaccggac taccgtattc taattgcccg tgatggctta aaatcacgtg
    32461 cctaaggaca atgacttctt ctttggtatc atcgatttgt agttctgaaa tcacttttgt
    32521 aatttcttcg ttaatgagag aaatatgccc aatcaagtta ccacgaacgg tgtattctgt
    32581 attatctggt cctgttaatt ctatgacttt agctaagtca tgtaacataa tacctgcaaa
    32641 cagtagactc ttatttaagt cagggtagat atctccaatg ctatctgcta gtctgaccat
    32701 cgtagcagta tggtaggcga ggcctgactc aaaagcatgg tggtttgttt tagctgcagg
    32761 ataagtataa aattctttat catacttacg ataaagagcc cttacaattc gttgccacgt
    32821 tgcattttca attttaaaga gcatctgttc caaatagtca cgtacttctg tcacactgac
    32881 aggtgccttt tctttgaagt cctttggatc attgggctca cctgggcgaa catttcgcaa
    32941 ggtgatttga ttaacctgag gggtaccatt atacacctcg cgtcgccctt tcataaacac
    33001 gactttacca gcagtaaatt cttcaacgtt ataaggttgg gcatcccaca gatttcctga
    33061 aatctcgcca gtgtcatcct gaaaggtaag gctaataaaa tctttaccag ctcttgtctt
    33121 acgaacctct gccgacttaa tgaggtagaa cccttcaaaa agctggtctt ttttcatttg
    33181 attaattttc attattttcc tcttctaata agggcatgtt caagagagat tttgttgctt
    33241 ggtcttgata agtttcaacg gtattcaagg ctcgaacaat ggcatttgtc cttgttgaaa
    33301 tgagctgatc cagcgtatta ttagctgtat tcatttgttt ttgagccttg gcaagcaggc
    33361 cgccaaattt atcgaattct aacttgacat tgcctaaaat tttactgatg tcatcagcat
    33421 ttttttggat attaagggtc ttgaaaccaa cagataagga attgagcaaa gcagacaggg
    33481 tcgaaggacc tgcaaccaca atattttctt cccgacgaag gctatcaaag aaagccgcat
    33541 ttctgaccac ttctgaataa agaccttctg ttggtaagaa cataactccg aaattggtcg
    33601 tctctggggg gttcaagtac tttttatgaa tgtctttggc aaagcgtttg atagctgcca
    33661 gaagtgcttt tcggctagcc tcgatggcca gtttatcacc aacttcgtaa gcatcttcta
    33721 atcggtaata atcttcaaga gggaattttg agtcaatcgg taggtaaata taaccgcctt
    33781 gaccatttcc tgggagctta atcgcatatt ctacgcgttc actagaacca ctaaccgtta
    33841 caaattctct ttcgtactgg cttgatgtca tgatatcctc aatgatttgg cctagttgaa
    33901 gttcgcctaa aatgcctcgt gttttggtat tggacaaaac cttatttaaa gtacccacat
    33961 cttgagccac gctacgcatt tctcccaaac ctttattgac actttctagt tgcttggata
    34021 cagaatcgaa agaggcgtgc agacgatttt ttaaggtttc ttccaatttt tcttcaacga
    34081 tctggcgcat tttctccaaa cgtttttcgt tagattcttg catatttttg agcgattggt
    34141 tgacctgctg gttaattttt tctaagcgtt tgtcagaccg gtccctacta tcagacaaac
    34201 tacggtgcaa gacgtcacga atatctgtta attgttggta aaggtctgct tgttgtcggt
    34261 tcatcagctg tgttagctct aacaattgtt gcttgttagc tgtatccaac tggtaggtca
    34321 tttggtcaga caaattatcc gcgttgcctt ctagggtttg ggcaagctga tgttgaaggc
    34381 cgttgacttt gaacaacaga taagccccta aacctaagag aaccaagacc aaaaggaaca
    34441 agataaggtc catactaact ccaatcttta ctttgaataa taatcaagta gccacttggc
    34501 aaactaactg taataggttg atggataaag gcattactgg aatagatttt ctttttgaaa
    34561 aaattatctt gcgtcaactc aaatttagca ccagtaatgg tcaagtcagc ttctccttct
    34621 gccataaatg ccacataggt catcccttct tcttgatgga taaggtgctg acctgccggg
    34681 cggtaggtaa tcatattttg ttggtcacgc aaggcgattt gtgccataaa gggagcaata
    34741 ccagggtcgc taggcaagaa aatattggat aagaggtggt ccattcgacc cccaaaagcc
    34801 ccaaaaatgg tcacttccgc ctcaggaaaa cgagcaaaga cctctttaag ggctaattcc
    34861 gtatccgtat catttttttc tggatgagca gtaataaaaa gctctgcctt ctcttttata
    34921 tccgtaaacg ctttctggga aaccgaatca aaatcaccaa cagccatatt caaaggaagc
    34981 ccattttcta ataaaaatag gctccctcta tcaataccga caaaataatc aaaatcacgg
    35041 ctgatataag agagatctcc tcccgcaaaa agagcaactt tagacattca aggccgtcct
    35101 taaggtttgg acttggctca ctaggtcact ggccttgaaa aggtaagaac ctgccacaaa
    35161 gacattggcc cctgcttcat aacaagcacg aatggtctta ttgtctactc cgccatcaac
    35221 ctcaatgtca aaggacaatc ctttttcatc tcgccatttg gctacggtag ccactttttc
    35281 taaacattct gggataaagg cctgaccccc aaaacctggg ttgactgtca taatgaggac
    35341 ttggtcaact aagtctagca aaggttctag ggctgttgca ggagttcctg gattaatcac
    35401 tacccctgct ttcatgccag ctgccttgat tttttgaagg gctccatgaa tatgacgagt
    35461 actttctgtg tgaatggtca tgatatcagc accagcttga gcaaaagcct caacatagcg
    35521 ttcaggatca accaccatta aatgacaatc aaaaaccaat ttactgtgct ttctcatact
    35581 tgccacaaca tctgcaccaa aactgatgtt aggaacaaat tgaccatcca taatgtcaat
    35641 gtgaacgtat tcggcatctg tttcttcaat acgaactagc tcagaagcaa aattagcgta
    35701 atcagctgct agaatagatg gggcaatttt tagagttgac atggagtaga cctactttct
    35761 tttgataact tttttatatg tttcacgacg gttttcaatt tcactgagaa attgcaggta
    35821 atgctcataa cgaactggcc acaactctcc cgtttcaagc gctgccttga cagcacactt
    35881 gggttcgtgg gtatgggtac aggatctaaa cttacactca tggctcagcc ggcgcagctc
    35941 tggaaaagcc tcgttcaaat cttcagcatt agcaatatca tagtctaatg atgagaaacc
    36001 tggcgtatcc gcgatttttc cgccatgggt attgtaaaaa ctcacagctc gggtggtgtg
    36061 gcgaccacgc cctagactat ctgagatttc tcctgtttca agagccaatt cgggggcgat
    36121 tcggttgaga agggttgatt tcccaacacc tgtttgtccc ataaagacgg taattttatc
    36181 agctagcaaa ggcaacaatt cctcaagact ggtcacaaaa tcgtaaccga ttgcctgata
    36241 ctgtcgacca atagccttaa tctcctcggg actatctaat aagtccatct tagagatata
    36301 aaccactgga tgaatggctt tgtgttcaag caagatgaga aagcggtcta gaagattgct
    36361 gttaaattct ggttctttag cagacataat aaccactgct tggtcaatat tgacgatagg
    36421 aggtcttacc aaactgtttt tacgaggatg aattgctaaa atataacctt cagagttgtc
    36481 ctctgctgag aaatccacga tatctccaac ataaggtgtc tccccgcgct tcctaaaatt
    36541 accacgcgct cgcgtctgat atacctgtcc ttctgactcc acgtaataaa aaccagccag
    36601 agatttaatg attttacctt gcaactgtgc tcctttaccc tactataata actctattat
    36661 atcagaaaac cgctcccaaa tcagcatttg agtctaagtt tcacttgctt taaaaactgt
    36721 caagattctc tagaccactg gctatcattt aggtcactgc tttttaaaaa tagaatattt
    36781 tatcaactaa aaatcagatc actgatgatt ttttgaggta ggaaacgata tgaattttaa
    36841 gaagaccttt gctatttacg aaaaagagtc taaccgtacc gctatagtca cgctcttgtt
    36901 aattgcccct ttttttccgg ggtattaaaa aaactagctc tgcactgcga tgccttaacg
    36961 gtcagcttca ataagaaaaa tccccctgaa ctgaacattt ctgttttgtc tacaagggaa
    37021 tttttttatt gtcaccgggg gaaagctttt ataatccaac ttcttttaaa gcatcagcta
    37081 atttgccaaa atcttgaatc gacaaggcct caccacgaat agaaggcttg atatctgcta
    37141 gtgccagacc tttttcaagt ttagccttga tgtcttcaga cttgccaaaa tggctagtca
    37201 agttattcca cagggtcttg cgacgatgga caaaactgag acgagacact ctgaaaaaga
    37261 aatcttcgtc ctcaacctca atcaaaggct ggtcgcgacg caccattttg aggatagcac
    37321 tatcgacatt tggtgcaggt acaaagacgg tgcgcggcac aatgaaggca accttggcag
    37381 tcatgtaata ctgcaccgca atggacaagg aaccataagc tttagtgttt ggctccgcag
    37441 aaatacgatc tgccacttca cgctgcatca tgactacaaa ctcttggaat ggaattttgc
    37501 tctcaatcaa gtgcatgaga ataggcgttg tgatgtagta aggtaggtta gccaccacct
    37561 tgataggcaa atcaggattt ttaaactgct tgatttgggt ctgcaaatca gctttcaaaa
    37621 tatcttgatt gaccacttgc acattatcaa aatcgcgcaa ggtatctgcc aaaatcggca
    37681 ccaagcggtc atcaatctca aaagccatca cttcagcagc attttctgcc aaaaactccg
    37741 tcaaagcccc aattccagga ccaatttcga taacgttgac attctgatca atctcagccg
    37801 tgtcaacgat tttctgtaaa atattggtat cggtcaaaaa gttctgacca aaagatttct
    37861 taaaggtaaa tccgtgacga tcaaggacag ccttggtcac gctataatct gcaattctca
    37921 tatattctct tctttttatg atcactttct ttttggcatt tgaaccacta gcctaaactt
    37981 ttttgccagg acacgccatt cagttaatgg agctgttata ttttattgta ctctttactc
    38041 ctcatatgtc tccatcactt cttccacttc tgctagggta atgccaaata attcgaggcg
    38101 cttgagcagt tgtttgccgt tggcataacc gatgcggagc ttttcaccca agtattccct
    38161 gcgtttacgg ctatctgacg ccattaaaag ccctagacga atcaggtctg tttgacgaat
    38221 gtcaaaataa gactcatcat catattgctg agtgacatga gcaagtgcct tttggagatc
    38281 ctcaaatctg gcatgttcaa cccctaagga acggccctta ctcttagaac tcggaaccgc
    38341 ctcgtttcgg tttaaaaagg catgacgagc tgttggcaca gcagccataa tgagcttacg
    38401 aatgcgctca ccattataat ctgggtctgt taaaacgata acaccacgca aatcgtttag
    38461 gcgattgatt cgttctaaat cttcttcagt gatagcagag cctctagtct cataggtatc
    38521 cacctcgtaa aaacggcgaa ggttagccgt gtcgtccttg ccttctacaa caagaacctc
    38581 ttgaatatta attttttcag tcaagcttga ataccctctt tgcattagca gtcgttgctt
    38641 ttgcaacttc ttccacagtc atcccccgta gctctgcgat tttatcaacc acatagcggg
    38701 tataagctgt atgattttgt ttgccacgtt ttggaactgg tgtaagataa ggggcatctg
    38761 tttccaccaa aatcttatcc aaaggcaagt gctgcgctgc ctcttgaata tcaagagcct
    38821 ttttgaaagt gaccacacct gaaaaggaaa tcatcatgcc aagttcaatg aaacgttcag
    38881 ccatctctaa tgaccctgag taagaatgca tgatgcctcc acgagggcca acaccagctg
    38941 ctttgatgac ctcataggta tcttccaagg catcgcgggt gtgcaccaca aaaggcaaat
    39001 catggtcttt tgctaattgc atttggcgct taaaaacctc tatttgcacc tctttggggt
    39061 cctccatcca ataatagtcc aaaccaattt cacccagggc aatcactttg ggatgtgata
    39121 attgagagac gatagactcc tcaactgctt cagaataaga gcctgcttct gtcgggtgcc
    39181 atccaatagt tgcataaata ttggcatatt tattggctag agttagtgcc ccactaatag
    39241 tggcctggtc aaagccaacc acattatggt aggccacgcc catttcttga gccaaagtca
    39301 attcttcagt ttcgtgtcct tgaaattctg ctacattcag gtgcgtatgg gtatcaaaaa
    39361 tagttagttt ttctacttta tttgtcatga tgttattata acataaagat cttaaccaca
    39421 tcagaaaact tggtgagaac ttctgccgtt taggttgatc gtaaaaccct ttgctagctg
    39481 acacttgtct attttctact tttttgacaa atgaccttta atagtcggct cctacataag
    39541 ccctcaaaaa tactacaacc tactcaaata aagtgggttg aacaaatctg tatcacaaaa
    39601 agggtcgcta ccttctgtta gcgatctatg ctatactagt aggtagttaa actgtaagga
    39661 gtgtgctttg ctatgcctaa aaaccaccgc ctaattacca aaatcgaagc atcattggaa
    39721 catatgacca gtttagaaaa agggattgct cattttttta ttacaaccga tctgacacct
    39781 caagagttga ccgcatccga gatagttaag cgactacaca tctctcaagc cgccttgact
    39841 cgatttgcaa aaaaatgtgg ttttactggt tatcgtgctt ttgcctttga ttaccttcac
    39901 agtcttcaag aatcacaaga gactttccaa tctattcact tagaattgac aaagcgcgtg
    39961 ctgatggact acgatgctct tattaataaa acctatgagc tcgttaatga ggaaaaatta
    40021 ctgaacttag ccaagctgat cgattcttct gagcgagtct atttctttgg caaaggatct
    40081 tctggactag tagcaagaga aatgaagcta cgctttatgc gacttggttt aatctgtgat
    40141 gcttattcag acactgatgg ttttacttgg gcaaatagcc tcgtcaatga aaattgcctt
    40201 gtttttggtt tttctttatc tggcaaaaca aactctgtca tcacagcact tcatcaagct
    40261 agtcagcgag gggccaaaac tatcctctta acaacagata atcaaaccga atttgacgac
    40321 tccttagata ttattcccgt atcatcaacc caccaactac attatgggaa tcgtgtgtca
    40381 ccacaatttc ctcttcttat tatgatggac attatttatg cttacgtttt agcgattgac
    40441 aaaccgcaca aagaaaaaat cttcaaaaac actattattg acaaagaaaa taacgacctt
    40501 tagactacaa tagcaaaaag ggcgttgttt tctttttaaa gggtcgtcat tcacctcccc
    40561 cagtatactt aaacaagaac tcttcacgtc atatagactc acagccacta agattagcta
    40621 ctcgctaaat tattttcgat tttctcaaga gttataaatg aacaggatcg ctcattcttt
    40681 tgtttaaaat ggtagtaagc tcctaatata ccagcattat ttccatgact agcaaacttc
    40741 agctgagttt tcttggcaag actagaaacc aagtagctat caagagctgt ctttaattta
    40801 tcagctaaat agtctttttg cgccatgatt ccgccaccaa gcaccaccac atttgggtta
    40861 acaacatagc agatattagc aataccttgt cctaagtaat ccacctgctt actaatggct
    40921 gctatacaaa tcgcatcacc cgctttagcc tgctcaaaaa tacgacgacc atcccattgg
    40981 ctaatgtcat cgccataagc taaggccacc tcttgaacaa gagctgtggt agatgccaga
    41041 tcctgaaact gaccatctga caaatgaagg taaccaactt cgcaagctga atgactacta
    41101 ccatgaaaaa cttgggaatt aaacaataaa cagccaccga ttcccgtccc aattgtcaag
    41161 caaagagcca caggataatc cttggcacta ccagaaatag cttcggctag accagcacag
    41221 ttaacatcgt tttccacttc acacggtaac ccgaaagtct cttcaatctc ttttttaaac
    41281 tgagttccag catagttagg aatctgaggg ccggcataaa agatttctcc cttatcagga
    41341 ttaaccattc ctgcagaaga aatggccact ccagccagat ccatttggtc ttgataggtc
    41401 tttaccaagc ccttgacctt ttccaaaata gagggaccac ctttataagc ctcagtagcc
    41461 atttccactt tttccagcaa ttccccatct tcagaaagca aaccatactt gatagcagta
    41521 ccaccaatat caattgctaa atagtatttc atctccttta ccccctcgcg ttttaacaaa
    41581 aggtttcctt agcttgacta ataagggaag cggcccgttg gcaaatgacc atgtcttcct
    41641 caactaactc agataatggg gaacgaacag atccaatatc aaggccttca ttaatacgaa
    41701 gaacttcctt aattacccca tacatattgc cgtgagcaga aacaaggaca ccgataatct
    41761 cattaatagt atattgaagg gccttggcct tttctaaatc cttgtcagca ataagttggt
    41821 tcagccttaa aaataattct ggcatagccc cgtaggtgcc accaatgcct gcagcagcac
    41881 ccatcaagcg ccctcctaga aattgttcat ccgggccatt aaaaacaata tggtcgtccc
    41941 caccaatcgc acagaaggtt tgaatatcct gcactggcat ggatgagttt ttaaccccaa
    42001 tcacgcgctt attagccaac atagtcttat aaaggcttgg cgtcaaggca acccctgcca
    42061 gttgaggaat attatagatg ataaaatctg tgtgaggagc agccgaagaa atagcattcc
    42121 aataatcagc aaccgcatat tctggtaacc ggaaataaat aggcggaata gctgcaatgg
    42181 catccacgcc caaacgttct gaatgagctg ccaattcaat actatcttta gtattgttgc
    42241 aggcaacgtg attaataatc gtcagcttgc ccttagcgac tgccatgaca ttttctaaca
    42301 ccaattgacg gtcaaaaacg ctctggtaaa tacattctcc agaagagcca ttgatgtaaa
    42361 gcccctgaac ccctttgtca atatagtact gggtcaaggc acgcacacgc tcagggctaa
    42421 tagctccttg gtcatcataa caagcataaa aggcaggaat aatgccttgg tatttcgtaa
    42481 gatctgtcat agtaatgtcc tttattcaat gtcattatta agtgggaatc gcctaagaag
    42541 ggattccatg ataatcaagt agaggtaagt taggctactg atgccgatga tagctagcaa
    42601 agacacgcct ccaaataacg ttaacagaga caattgtagg ctaaatatcg tgagacaaat
    42661 aagagccaag aaagcaaaac tccatggaaa aaagagtccg gctagtaaaa agcttcgctt
    42721 aaacagcgta gatagggaaa ggtctctttt gacggcctga ggataagcgt acaaaaagag
    42781 tataactacc aaaaataaaa cagcaatgca aagtacttta aacccttgaa aaactaggcc
    42841 tgattggttt cgaattaaga aaagatctaa gacacaaata ctcatcatca aaagctcaat
    42901 aagacctagg cgcatcccac ttttaaaata atgtttaaaa tgagagctat aagtagtaac
    42961 aagctgacta acttgacctt ctcgccaatc caacaaactc gcatacaaag ccattttagc
    43021 aaccccaatc gttagaaggg gaaggcagga caagacaaat aagagattaa acacgagcaa
    43081 atcaaacagt gctgcgctag ccctcatcca tttactatca agcttgaaga gagagtgtaa
    43141 aagtccctgt tttttcgatg tcaaatcaca acttcctttc tagaaatacg cttacaaaca
    43201 aaagctaact ctcctcttaa acgcttaaca catgacttgc ttcccttttg acttatctat
    43261 ctatgcacct aaattaagag gcaacctata gattaagctt agtgacacgc tttatttagt
    43321 ctaacctttc acagcaccca tagtaatgcc ttgggtaaat gatttttgga agacaagaaa
    43381 taccgtcaca ataggcactg cagccatggc agcccctgcc ataatcaagc cataattagt
    43441 agccatttca gcttgcatag tggcaacccc aagtgaaatc gttaaatttt cccgagaggt
    43501 taacatcacc aactgcataa aataatcatt ccaagtattg ataaaggtaa aaattgctag
    43561 cgctgcaaag cctggtttga caatagggaa agccacattg aaaaaggtac gaatttcgcc
    43621 acatccatca atcttggcgg attccaataa ctcggttgga atattttctg agaactgttt
    43681 cataaggaaa acaccaaatg gccagcccac aagaggcaaa ataacagccg ccaaagtgtc
    43741 atggattccc ataaaattaa caatccgcac aagaggcact agaacaacct gttttggcaa
    43801 ggccatagca gcaataaaaa tcgaaaacaa aagccgctgt ccataaaacc gctttttggc
    43861 caaagcatag ccagccaaag aggaagtgcc acaaaccaag aacatggtcg ccaccgaaat
    43921 aaagacacta ttccacaacc attttaaggc tggattttgc actaccaagg ccttaaaatt
    43981 ttcaatagta ggtgcctttg gccaccattg gggtggaatc ataatggtat cggcttgagc
    44041 cttaaatgct cctgtcataa tccaataaaa tggaaaaata aacaaaatgg tcaaaacaca
    44101 tagcatcaca gcggtcaaga tatctgatgc ggttagtttc tttttcgtca tcttaatatc
    44161 ctcctaatat tccacatcat tacctaaaat tttaaattga gcaaagctga tgattgcaat
    44221 catgactgcc aagaatacac ccattgtgtt ggcatagccg tattcagaga gcttaaaggc
    44281 tttttcatac aaatagtaca tgagggtgct ggttgaataa tttggccctc cagacgtcaa
    44341 gagttgaatc aaagcaaaac attggaagga attaatggtt gttataacag caatatataa
    44401 ggttgttggc aggagacttg gccacttgat attccaaaac acctgaaatt ccgtcgcccc
    44461 atccacacgc gcagcttcta ccaaagagtt atcaatattt cccatagctg caatatatag
    44521 aataataggc tgcccaacag atgtggttaa taaaataaca ataatagcta acaaagccca
    44581 gtgcttatct cccagccaac taatgttttg ttcaatcaca tgagcatatt ttaagacata
    44641 attcaaaatc cctgacatcg gatcatagat ccatttccaa accaccgtca ccgcaacact
    44701 tccggtaaca acaggcagaa agaaaactgc ccggtaaaac gaacgcgcca ctacattttt
    44761 gtcgtaggtt ttagccgcca caaagaggga aaagaaaact acaacaggta ccgaaccaat
    44821 aacaataatc aaggtgttaa taagagactt catgaaaatg ggatcttgaa acatcctagc
    44881 ataattagca aaaccaacaa aggtaaaatc cgtcatggaa taattgaaaa aactcgtcac
    44941 aaagcccata atcatcggta tcaagacaaa aatcacaaag aaaaccaaga ccggagctaa
    45001 gaaagcgtat gagatgagcg tctctctcat ttttaattta ttgacgttca cttgaaatac
    45061 ctctttttct attaatctct cctaaaaaag gaaaggctcc tttccagtga ccatttgaca
    45121 tgtgccgtga aaagaagcca cttgttctga acacttattg tgtttttttg attgtcttgt
    45181 ttgctttttc agtgaaggct ttcaaagcat cttctggctt ttcatcacca ttagagatgg
    45241 cttgaaccat tgggaaccaa agagttctca tttcagcaaa cccatcaatc gtgttgtagt
    45301 atggtgagta gaattttgtc cattcagcaa ttttttccat tcgtttgtct ttgtaaagat
    45361 ccccataaga agttcttaca gggaaagcac ctgtacgaac aacattttta ggtccccatt
    45421 ctttatcatc agcgataaat tggataaatg tcttagaggc agcgactttt tgttcatctt
    45481 tgttattaaa gaccgcaaaa ccatttacga ggtattctag ttctggttta ccatcatctg
    45541 atgggaatgg gatttcaagg taatccactt tactagcttc taacaattta gcttggatgc
    45601 ctggttgtgc aggcgcccaa agaatggtaa aggaagtttg gccattcgca aagttttgaa
    45661 tatcagctga accatcgtac tgagagccat tcatcattaa accatcttta atccaattgg
    45721 aaatcttggt catggcttta atagagttag catcatctgt ggtgtatttg gttactttat
    45781 catcggtaat atgactgcta taaaggttgg caaagaaggc acgcggtcct tggtcaccac
    45841 cttgaccatt agcaaagaaa gaacctgggt tatatccttt gtccttcaat gctttcaaga
    45901 ctttttcaaa atcgtcagtt gtccaacctt ctttcaccag gtcaaggacg ccagcatctt
    45961 tgagcatttt tttattcaac gccatgtaga atggtgcaga gctaatagga tacatatagg
    46021 ctgtatctcc tgcttttgag gcttgaatca acttgtcatt gttaacatct ttggtaaatt
    46081 cttcggtaaa caagtcattc aagtcagcca atttcccatt tttaccatat tgaatgatac
    46141 ggcctggagc atcaaagagg acatcaggag ctgttccagc ttcaatagca gttgtgattt
    46201 tctcaggacc agatgtaaaa tcaatggttt ccaattttac cttgatttct ggattagttt
    46261 tctcaaaggc agcaatcaac ttcttttcgt aagttcccac accatcttca gctttttctt
    46321 gcgtaaagac tgggaaagcc caccatgtga tttctgtttt agcagcatca gatttacttg
    46381 cactggcctc tttctggctc tttccgccac aggctgctag tcctaaaaca gatgcaccaa
    46441 gcatcgctaa tgaagctaac ttcttcatgt tcatcgtaaa atctcctttt tttgatgtgt
    46501 gtttctagtt tgacaaccac tattaggatt tgagcgcttc gataaaacgc tctgcaattt
    46561 ccttaggcct tgtgatggcc cctccaacaa caatacctgc cacacctaag tcattaattt
    46621 tcttggcttc ttctggggaa tgaatctttc cttcggcaat gacagcaaca cctgctttgc
    46681 aaagagcttc tatcaatgcc acatcaggac ctgcttcctg acggctatac ggggtgtagc
    46741 ctgagagggt cgttccaaca aaatcaatgc cagcctgatg ggccactagt ccttcatcaa
    46801 aggtactaat atctgccatc aaaagctgat tggggtactt ttccttaact tgtcgaataa
    46861 agctagcaat atccaagcca tcatgtcggt cacgcttggt acaatccata gcaatcactg
    46921 caatatttaa ggcagctaat tggtccactt cagccatcgt tgccgtaata aaaggctctt
    46981 gcggcgggta atcttttttg atgataccga taattggtag gtctgttatg gcttgaattt
    47041 ctttaatatc cctaaccgaa ttagctctga tgccgacagc accagcttct tgagcagctt
    47101 ttgccagcag tggcataata cccccagtct ctgaataaag aggctcacct ggcaaagcct
    47161 gacaagaaac gataatccca ccctttaact gctccatgag cttttctttg gttggtttat
    47221 caggcatagt ttctactcct tgtgtttctt agttttaata aaaataacgt tcacaaagtt
    47281 attataacaa aaaataaagc gctttcaata tcaatgagac ttttagaatc ta
//
LOCUS       DATTYN010000013        47109 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.13, whole genome shotgun sequence.
ACCESSION   DATTYN010000013 DATTYN010000000
VERSION     DATTYN010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47109
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.13"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..261
                     /locus_tag="VB649_000914"
     CDS             <1..261
                     /locus_tag="VB649_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1669873.1"
                     /translation="NGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKA
                     RTRQTGGFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL"
     gene            complement(386..634)
                     /locus_tag="VB649_000915"
     CDS             complement(386..634)
                     /locus_tag="VB649_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEP1669874.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG"
     gene            complement(688..1608)
                     /locus_tag="VB649_000916"
     CDS             complement(688..1608)
                     /locus_tag="VB649_000916"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEP1669875.1"
                     /translation="MSNEFINFEKISRESWKTLHQKAKALLTQEELKSITSLNDNISI
                     NDVIDIYLPLINLIQVYKIAQENLSFSKSLFLKKDIQLRPFIIGISGSVAVGKSTTSR
                     LLQLLLSRTHPNSQVELVTTDGFLYPNQFLIEQGLLNRKGFPESYNMELLLDFLDSIK
                     NGQTAFAPVYSHDIYDIIPNQKQSFNNPDFLIVEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSSHIETWYIERFLSILKLAKRDPHNYYAQYAQLPRSEAIAFARNVWKTVNLENL
                     EKFIEPTRNRAELILHKSADHKIDEIYLKK"
     gene            1843..2469
                     /locus_tag="VB649_000917"
     CDS             1843..2469
                     /locus_tag="VB649_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP1669876.1"
                     /translation="MKKYLKKIGKMMTKMYYDENPDSLHDIHEVKVELLNHPFTFLTD
                     SGVFSKKMVDFGSQVLLKTLNFKENERVLDLGCGYGPLGISLAKVQRVDATLVDINNR
                     ALDLARKNATNNQVAVTIFQSNIYENISGHFEHIISNPPIRAGKRVVHSIIEKSIDFL
                     VVNGDLTIVIQKKQGAPSAKAKMATIFGNVEILRKDKGYYVLRSIKQA"
     gene            3122..3511
                     /locus_tag="VB649_000918"
     CDS             3122..3511
                     /locus_tag="VB649_000918"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEP1669877.1"
                     /translation="MGTTDLVSCAVQASEYAYVPYSHFPVGAALKTKDGTIYTGCNIE
                     NVSFGLTNCGERTAIFKAISDGHKELVEIAIYGETMQPVSPCGACRQVMAEFFDPSSL
                     VTLIAKNGQTVEMTVGDLLPYSFTDLI"
     gene            3605..4657
                     /locus_tag="VB649_000919"
     CDS             3605..4657
                     /locus_tag="VB649_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEP1669878.1"
                     /translation="MNKKFIGLGLASVAVLSLAACGNRGASKGGASGKTDLKVAMVTD
                     TGGVDDKSFNQSAWEGLQSWGKEMGLQKGTGFDYFQSTSESEYATNLDTAVSGGYQLI
                     YGIGFALKDAIAKAAGDNEGVKFVIIDDIIEGKDNVASVTFADHEAAYLAGIVAAKTT
                     KTKTVGFVGGMEGTVITRFEKGFEAGVKSVDDTIQVKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQAAGGTGAGVFNEAKAINEKRSEADKVWVIGVDRDQKDEGKYTSKDGKEA
                     NFVLASSIKEVGKAVQLINKQVADKKFPGGKTTVYGLKDGGVEIATTNVSKEAVKAIK
                     EAKAKIKSGDIKVPEK"
     gene            4796..6328
                     /locus_tag="VB649_000920"
     CDS             4796..6328
                     /locus_tag="VB649_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1669879.1"
                     /translation="MTQHVIEMREITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGEIVINDKPVQIDSPSKSAKLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLNQASKDIKVLSEKYGLAINPSAKVSDISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIKELMTIMKNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIETVDVAGATSQDLAEMMVGRSVSFTTSKKAAEPKDVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVKSGSIMIKNNEVTHLSSRKITELS
                     VGHVPEDRHRDGLILDLSLAENTALQTYYKQPLSQNGILNYTKINDYARQLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRDPDLLIVSQPTRGLDVGAIEYIHKRLIKERD
                     KGKAVLVVSFELDEILNLSDRIAVIHDGKIQGIVLPENTNKQELGILMAGGSIHKEEG
                     HV"
     gene            6321..7385
                     /locus_tag="VB649_000921"
     CDS             6321..7385
                     /locus_tag="VB649_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669880.1"
                     /translation="MSKNAQKIAVPLISVLLGFLLGAIIMVIFGYDPIWGYEGLFQIA
                     FGSVKNIGEIFRSMGPLILIALGFTVASRAGFFNVGLSGQALAGWISAGWFALLNPDM
                     PRPLLILMTALIGMIAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIVQRGY
                     PESVKQSIDSTIQVSDNASYQTHWLSALTNNSRINIGIFFAIIAIALIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSSKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     VGFDGMAVSLLAANSPLGIFFSSFLFGVLNIGAPGMNIAGIPPELVKVVTASIIFFVG
                     SHYLIERYIIRPKKLVKGGK"
     gene            7387..8343
                     /locus_tag="VB649_000922"
     CDS             7387..8343
                     /locus_tag="VB649_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669881.1"
                     /translation="MSLVTIFALLMSSMLIYATPLIFTSIGGTFSERSGVVNVGLEGI
                     MVMGAFSGIVFNLEFAETFGKATPWIAVLVGGIVGLIFSLIHAVATINFRADHIVSGT
                     VLNLLAPSFAVFLVKAMYGKGQTDNIQQSFGKFDFPGLSQIPVIGDIFFKNTSLIGYF
                     AIAFSFFAWFLLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPL
                     LEKIPTVYLQIAPYMVTIIILAAFFGQAVAPKADGINYIKSK"
     gene            complement(8557..10275)
                     /locus_tag="VB649_000923"
     CDS             complement(8557..10275)
                     /locus_tag="VB649_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEP1669882.1"
                     /translation="MTYTENFQKWLDFEQLPDYLRQELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLIETKEEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAQHGIKSYVFEALRPTPELSFAVRHLNAYAGIMVTASHNPAPFNGYKVYGQDG
                     GQLPPADADALTDFIRAIENPFAVELADLDESKSAGLIQVIGEDVDMEYLREVKDVNI
                     NQDLINNFGKDMKIVYTPLHGTGEMLTRRALAQAGFESVVVVESQAKADPDFSTVKSP
                     NPESQAAFALAEELGREVDADVLVATDPDADRLGVEIRQPDGSYKNLSGNQIGAIIAK
                     YILEAHKTAGTLPENAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDEIYKE
                     YGYFAEKTISVTLSGVDGAAEIKKIMDKFRENGPKQFNNTDIVLLEDFQKQTATKNDG
                     TISNLTTPPSNVLKYTLADDSWIAVRPSGTEPKIKFYIATIGDTLDIAQEKIANIETE
                     INTFVG"
     gene            complement(10451..11020)
                     /locus_tag="VB649_000924"
     CDS             complement(10451..11020)
                     /locus_tag="VB649_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP1669883.1"
                     /translation="MNHRKSADISRIAIFFAIMLVIHFVSSLVFNIWPIPIKPTLVHI
                     PVIIASVLYGPRIGAILGGLMGIISVITNTIILLPTNYLFSPFVDHGTFASLIIAIIP
                     RILIGITPYYCYKLIPNQFGLIVSGIIGSLTNTIFVLSGIFIFFATVFDGNIKALLTA
                     IISSNAIVEMIISAIITFVLIPTLSRLKR"
     gene            complement(11078..11623)
                     /gene="coaC"
                     /locus_tag="VB649_000925"
     CDS             complement(11078..11623)
                     /gene="coaC"
                     /locus_tag="VB649_000925"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEP1669884.1"
                     /translation="MTKHITLAVSGSISAYKAADLTSQLTKIGYDVHIIMTQAATQFI
                     TPLTLQVLSKNAIHLDVMDEHDPKVINHIELAKRTDLFIVAPASANTIAHLAYGFADN
                     IVTSVALALPATTPKLIAPAMNTKMYQNPITQENIKRLSTIGFTEIPPKSSLLACGDK
                     GPGALADIDVILATIDTIWKL"
     gene            complement(11616..12308)
                     /gene="coaB"
                     /locus_tag="VB649_000926"
     CDS             complement(11616..12308)
                     /gene="coaB"
                     /locus_tag="VB649_000926"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEP1669885.1"
                     /translation="MTMKLIITSGGTTEPIDAVRGITNHSTGQLGKLITERFLQYHHD
                     VTLVTTKTATKLLPNEHLRIIEVETVNDLMAALKDQVPHHDILIHSMAVSDYTPVYMT
                     DLEQVSQADNLNCFLCEHNSEPKISSASDYQVLFLKKTPKVISYVKQWNPNIKLVGFK
                     LLVNVPQEELIKVARASLAKNHADYILANDLVDIQTGMHKALLISNNEVASADTKEAI
                     ADLLYERMTKHD"
     gene            12489..13340
                     /locus_tag="VB649_000927"
     CDS             12489..13340
                     /locus_tag="VB649_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HEP1669886.1"
                     /translation="MKGRIVITIRDLASLPIFVYGDGNKKVPGALSPFVWTEVFLKTI
                     NQEPNQLILHIWPMTRTVILGMLDRQLPYFELAKKEIGNNGYVPVTRNIGGLAVVADD
                     GILNFSLVIPDHFSESISISNAYLIMVDVIRESFSDYYQRIEYHEIKNSYCPGNFDLS
                     IAGRKFAGIAQRRIKKGIVVSIYLSVCGDQAARGQLIKAFYEAGTQGEVTKVNYPQID
                     PECMATLSELLETPFTVAEVLERLRLTLRQLGFSLTEKSPDQALLTNFDAVYERMQLE
                     VVRKEGK"
     gene            13337..14536
                     /locus_tag="VB649_000928"
     CDS             13337..14536
                     /locus_tag="VB649_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HEP1669887.1"
                     /translation="MKERFSPLFEPLTLPNGSQLDNRFVLSPMVTNSSTKDGYVTQDD
                     ISYALRRAASAPLQITGAAYVDPYGQLFEYGFSVTKDADISGLKELAQAMKAKGAKAV
                     LQLTHAGRFASHALTKYGFVYGPSYMQLRSPQPHEVKPLTGQQIEELIAAYAQATRRA
                     IQAGFDGVEVSSAQRLLIQTFFSTFSNKRTDSYGCQTLFNRSKLTLAVLQAVQQVIKQ
                     EAPDGFIFGFRATPEETRGNDIGYSIDEFLQLMDWVLNVAKLDYLAIASWGRHVFRNT
                     VRSPGPYYGRRVNQVVRDYLRNKLPVMATGGMNTPDKAIEALAHADFIGVSTPFVVDP
                     EFAHKIKEGCEESIHLRIRPADLKSLAIPQASFKDIVPLMDYGESLPKESRTLFRSLT
                     HNYKEIK"
     gene            14533..15531
                     /locus_tag="VB649_000929"
     CDS             14533..15531
                     /locus_tag="VB649_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEP1669888.1"
                     /translation="MKVSILDYGVIDKEKTPQEALLETRCLAQVADKLGFHRFWVAEH
                     HNIYAFAISSPELLMMHLADHTKQIRIGSGGIMPLHYSSFKIAEWIMTLEALHPNRID
                     LGIGNSLGTTLVQRALSSIHCKDSYSQVVTELYQYLNPDHLSPLPIFVNPRGNTYPQI
                     WTLSNSLETAELAGQLGLGYTFGIFPYIPKDPITEAKRVSAHYRKAFRPSKLLKIPKL
                     ILAVFIVLSDTDEEAEALAKPLDIWMLGQQDFNEFKTYPDVEEARNYHLTEKQREAIA
                     ANRSRMVIGSPHTVKKQLDRLIEACQADELLAIPLVPEFANRQRTLELLADLYVTI"
     gene            15573..15905
                     /locus_tag="VB649_000930"
     CDS             15573..15905
                     /locus_tag="VB649_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HEP1669889.1"
                     /translation="MKKIANYLLIEKTDDRYTISMTPELQDDIGTIGYAEFTDNDHLA
                     VDDIILNLEASKTVMSVLSPLAGAVVERNEAATLTPTLLNSEKAEENWIVVLTDVDQA
                     AFDALEDA"
     gene            15898..16710
                     /locus_tag="VB649_000931"
     CDS             15898..16710
                     /locus_tag="VB649_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HEP1669890.1"
                     /translation="MPSSFDLLGEMIGLLQTEPLTSSWACPLPNALTKRQDLWRALIN
                     QRPALPLSKDYLNLEDAYLDDWRASFVPVSVKDCQKTNYTSLFLYHGDIRYLAVDAIV
                     NAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAYHL
                     PASYIIHTVGPRITKGQHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF
                     PKKEAAQIAIKTVLKWQAEHPESKTLTIIFNTFTSEDKALYDTYLQKENNCE"
     gene            16703..17584
                     /locus_tag="VB649_000932"
     CDS             16703..17584
                     /locus_tag="VB649_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HEP1669891.1"
                     /translation="MSNWTTYPQKNLTQAEQLAQLIKEADALVVGIGAGMSAADGFTY
                     IGPRFETAFPDFIAKYQFLDMLQASLFDFEDWQEYWAFQSRFVALNYLDQPVGQSYLD
                     LKEILETKDYHIITTNADNAFWVAGYDPHNIFHIQGEYGLWQCSQHCHQQTYKDDTVI
                     RQMIAEQKNMKVPGQLIPHCPECEAPFEINKRNEEKGMVEDADFHAQKARYEAFLSEH
                     KEGKVLYLEIGVGHTTPQFIKHPFWKRVSENPNALFVTLNHKHYRIPLSIRRQSLELT
                     EHIAQLISATKTIYQKS"
     gene            17631..18650
                     /locus_tag="VB649_000933"
     CDS             17631..18650
                     /locus_tag="VB649_000933"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEP1669892.1"
                     /translation="MYLIEPIRNGKRITDGAVALAMQVYVQENLFLDDDILFPYYCDP
                     KVEIGKFQNAVVETNQEYLKEHHIPVVRRDTGGGAVYVDSGAVNICYLINDNGIFGDF
                     KRTYQPAIEALHHLGATGVEMSGRNDLVIDGKKVSGAAMTIANGRVYGGYSLLLDVDF
                     EAMEKALKPNRKKIESKGIRSVRSRVGNIREHLAPQYQGITIEEFKDLMVCQLLQIET
                     ISQAKRYDLSEKDWQQIDALTERKYHNWEWNYGNAPQYRYHRDGRFTGGTVDIHLDIK
                     KGYIAACRIYGDFFGKADIAELEGHLIGTRMEKEDVLATLNAIDLAPYLGAITAEELG
                     DLIFS"
     gene            18778..20448
                     /locus_tag="VB649_000934"
     CDS             18778..20448
                     /locus_tag="VB649_000934"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEP1669893.1"
                     /translation="MKSDIEIAQSVALQPITDIVKKVGIDGDDIELYGKYKAKLSFEK
                     MKAVEANEPGKLILVTAINPTPAGEGKSTMSIGLADALNQMGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLQQGNDLGIDPRR
                     IIWKRVLDLNDRALRQVIVGLGSPVNGVPREDGFDITVASEIMAILCLATDLKDLKKR
                     LADIVVAYTYDRKPVYVRDLKVEGALTLILKDAIKPNLVQTIYGTSALIHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKVPNLPKAPDAIVIVATLRAL
                     KMHGGVAKSDLAAENCEAVRLGFANLKRHVENMRQFKVPVVVAINEFVADTEAEIATL
                     KALCEEIKVPVELASVWANGAEGGLALAKTVVRVIDQEAADYKRLYSDEDTLEEKVIN
                     IVTQIYGGKAVQFGPKAKTQLKQFAEFGWDKLPVCMAKTQYSFSDNPSLLGAPTDFDI
                     TIREFVPKTGAGFIVGLTGDVMTMPGLPKVPAAMAMDVAENGTALGLF"
     gene            20533..22110
                     /gene="cls"
                     /locus_tag="VB649_000935"
     CDS             20533..22110
                     /gene="cls"
                     /locus_tag="VB649_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEP1669894.1"
                     /translation="MIIKKKAKVKYLLHKGKHGFLRGIFSRTTIIVLLIILQLVFLFQ
                     SYAWMEQYRVWITILESVFAITIVLYLVNSDMDAISRMTWLILIMIAPLLGSLFLIYT
                     KLDWGYRGLKQRINHLVDLSAPYLSDDDAILEVLKDSTSTTYHLVQYLERSRGNFPIY
                     NNTRVTYFPTGETFFDSLKEQLFLAKKYIFLEFFIIAEGQMWGEILSILEKKVSEGVE
                     VRVLFDGMNELSTLSSDYAKRLEQIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     SFTGGINLADEYINEVERFGRWKDAGLMLEGEATDSFLILFLQMWSITEKELIIDPYL
                     SDHSLKLPSDGYVIPYGDSPLDTDKIGKNVYIDILNHAKEYVYIMTPYLILDSEMEHA
                     LRFASERGVDIRIIMPGVPDKGVPYALAKTYYKALMTSGVKIYEYQPGFVHSKVFISD
                     NTKAVVGTINLDYRSLYHHFECATYLYRVSVIADIVNDFNEAQKQSLLMTSDHLKQRP
                     WYQKLIGLLVRTIAPLL"
     gene            22449..22787
                     /locus_tag="VB649_000936"
     CDS             22449..22787
                     /locus_tag="VB649_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669895.1"
                     /translation="MQIIKRDGHVADFDPDKIYQAIIKAARTVYVIDDTWRQNLTHVT
                     KKVVIDLEEAHVERPTINMVQSLVENRLMDAGYITIAEHYISYRLQRDLERNGYGDKI
                     VVHLRFEQIK"
     gene            complement(23258..24526)
                     /locus_tag="VB649_000937"
     CDS             complement(23258..24526)
                     /locus_tag="VB649_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEP1669896.1"
                     /translation="MTTKYQTIISNIEQDIQKQRLKKGDKLPSIRVLSKVYHCSKDTV
                     QRALLELKYRHLIYAVPKSGYYVLGNVSMPDNVLNLSLEDYNNMAYEDFRLCLNEALS
                     AKDKYLFHYYHKTEGLEELREALLLYLAENSVYSNKDQLLITSGTQQALYILSQMPFP
                     NAGKTILLEKPTYHRMEAIVAQLGLPYQTISRHFNGLDLELLESLFQTGDIKFFYTIS
                     RFSHPLGLSYSTKEKEAIVRLAQRYQVYILEDDYLGDFVKLKEPPIHYYDTHHRIIYL
                     KSFSMSVFPALRIGALVLPSGLKPHFLTQKSLIDLDTNLLMQKALALYLENGMFQKNL
                     RFIKRYLKQRERQLALFLKQNCPDIHYQLTPTHLVIDYTTSDSYRNFTLDKSDRIIIT
                     GKKRYLSIAINQQIQSKLNSLIKNTCGKSN"
     gene            24616..25482
                     /locus_tag="VB649_000938"
     CDS             24616..25482
                     /locus_tag="VB649_000938"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEP1669897.1"
                     /translation="MKRIIVANDLVGVGKVALSASIPLMASCLLEQVLLPTCLLSSHT
                     GGGQNPVKHTTSSILDVFLTDWDNKRIKFDGIFIGYFTTTRDGQKLLEWLSRKQLPLI
                     LDPIMADNGKLYQGFSQKHIDIMIKLTQKAELVLPNISEACLLTQTAYLVKNYDEEDI
                     RQVARKLAKLGPKQVVISGISFEEGSIGFAYYQSDSDQLTFHFGKQFPYHFYGTGDIA
                     SAIITAGFYYQLPLTQILDLVVSFLEKVLQNTLTLKRDLILGVAYESHLNYLTKSFKK
                     LLEEKNVISKIS"
     gene            25460..26017
                     /locus_tag="VB649_000939"
     CDS             25460..26017
                     /locus_tag="VB649_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP1669898.1"
                     /translation="MSSQKLANYIELSMYAALIFISVQVLRIPIGMQFIHLGNALVVI
                     AVLIYGSKKGALVASLGLGIFDVLNGYASVVWITILESLAICLILHLVYERAMQSSKK
                     PKAIITITVIAALSKLTINLIKYLLLAYIGTQLPLSVSFWVALGKIGGSFGTSFVTLV
                     AVPLLYPVIKNLKEKVIIGQAKRGF"
     gene            26151..27695
                     /locus_tag="VB649_000940"
     CDS             26151..27695
                     /locus_tag="VB649_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP1669899.1"
                     /translation="MSILEVKQLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDEGKVEWSKYVTAGYLDQHTVLESGQTVRDVLRTAFDELFKTENRIN
                     EIYASMADDKADIAVLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMESDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNHLDAEHIEWLKRYLQHYENAFVLISHDI
                     SFLNDVINIVYHVENQSLVRYTGDYYQFQAVYEMKQSQLEAAYERQQKEIANLQDFVN
                     RNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPNFEFKQARTPSRFIFQTKNLVIGY
                     DYPLTKEPLNITFERNQKIAIVGANGIGKSTLLKSLLGVIEPLEGHIVTGDFLEVGYF
                     EQEVTGVNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLILDEPTNHLDIDAKNELKRALKAYKGSILMVCHEPDFYNGWVTDTW
                     DFSKLT"
     gene            28060..29283
                     /locus_tag="VB649_000941"
     CDS             28060..29283
                     /locus_tag="VB649_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEP1669900.1"
                     /translation="MTNLTFYAKIGISEEEHDSFVKEHQQISVLQGSDWAKIKNQWEN
                     ERIGIYKEEKQVTSLSLLIKLLPLGRSIIYIPRGPVMDYLDRDLVVFTMKTLKDYGKT
                     KKALFIKYDPAILLKQYALGQEEEEKPLALAAIKNLQEAGVHWTGLTMEIADSIQPRF
                     QANIYTQENLEMQFPKHTRRLIKDAKQRGVETYRASQSELHKFSKIVSLTEKRKNISL
                     RNEAYFQKLMTTYGDKAYLHLAKVNIPQKLDQYRQQLNLINQDITRTQAHQKKRLKKL
                     EDQKASLERYITEFEGFTDQYPEEVVVAGILSISYGNVMEMLYAGMNDDFKKFYPQYL
                     LYPKVFQDAYQDGIIWANMGGVEGSLDDGLTKFKANFAPTIEEFIGEFNLPVSPLYHI
                     ANTMYKIRKQLKNKH"
     gene            complement(29325..30887)
                     /gene="guaA"
                     /locus_tag="VB649_000942"
     CDS             complement(29325..30887)
                     /gene="guaA"
                     /locus_tag="VB649_000942"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEP1669901.1"
                     /translation="MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKI
                     TAQELHEINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGK
                     VVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAIENTEKNLYGIQFHPEVRHSVYGNDILKNFAISICGARGDWSMDNFIDMEITK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLG
                     DKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEI
                     VWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            31054..32487
                     /locus_tag="VB649_000943"
     CDS             31054..32487
                     /locus_tag="VB649_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669902.1"
                     /translation="MLRKKRILGLFRPVELIFLGLLLSLVVSYLAWTNSFATLHNILA
                     TVGIVERSKDQQPRYHIGQAIQVQKSGPYHQWIGTINKQVEDIAENYRVSYHYEVVFP
                     IGKVTVSLPEHNLKKPDKPRFKKGDIVKLSSLTKKPHIKVYQGQLATIKQVKKRYDYS
                     LGGYQYDINLKDNLRLDGISEQDFVKPYYIRFNKGNSPEQNNRLLRKAFAYAKQHPNS
                     VISFPKGQFHIGSLPSQKDYFELPSDTAIIGHQTEFIIHGKMLWFGFPTGPKAEQGVR
                     NLVLTGVHFKANDLKKGDHFMIMADHGTDWHIYDNKFTMVHKRNSHIFDLGSLQNSLF
                     EKNQFIGYAPELVQDQQLLSKAQGHDFFSEVIQFDAAVHHFAWDGGLLSNIAPNYEAF
                     NQTRHLCHNITVSQNQFLPYIDPTGCLRAYSGSIGQHSSKVGVIRVLNNVFTSSIVTK
                     AKLTSWFMEPIHFPPNSPVIVAGNIIN"
     gene            32570..33268
                     /locus_tag="VB649_000944"
     CDS             32570..33268
                     /locus_tag="VB649_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP1669903.1"
                     /translation="MLPAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTL
                     RQAITLLVEEGILERRIGSGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQK
                     QLASDTEVKELNLDKTDLVIRMERIRYADSVPLVYEIASIPEKFIKTVKRADITEHFF
                     HSLIANGYEIGKSKQTIYAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRS
                     QYIGDRFEFYLENN"
     gene            33357..33698
                     /locus_tag="VB649_000945"
     CDS             33357..33698
                     /locus_tag="VB649_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEP1669904.1"
                     /translation="MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEI
                     ADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEK
                     ISILTSIDNRE"
     gene            33713..35275
                     /gene="ffh"
                     /locus_tag="VB649_000946"
     CDS             33713..35275
                     /gene="ffh"
                     /locus_tag="VB649_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEP1669905.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKKLSESDVQEVTKEIRLALLEADV
                     ALPVVKTFIKRVRERAIGHEIIDTLDPTQQILKIVNAELTSILGSETAEIDKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTDHSAVDIVRKGLEQARENRNDYVLIDTAGRLQIDEKLMEELRDVKALAQPNEI
                     LLVVDSMIGQEAANVAYEFNHQLSITGVVLTKIDGDTRGGAALSVREITGKPIKFTGI
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAEKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMAGNPALANIKVDENQIARKRAIVSSMTPAERENPD
                     LLNPSRRRRIAAGSGNSFVEVNKFIKDFNQAKSMMQGVMSGDMSKMMKDMGINPNNLP
                     KNMPAGMPDMSSLEGMMGQGGMPDLSGLGGDMDMSQLFGKGFKGKIGQFAMKQAMKRQ
                     ANKLKKAKKKRK"
     gene            complement(35410..36108)
                     /locus_tag="VB649_000947"
     CDS             complement(35410..36108)
                     /locus_tag="VB649_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1669906.1"
                     /translation="MFSGHQLKTARLSKGITQSELGRLLHVNKMTISNWEKGKNIPNE
                     KHLNALLHLFNVTSDYFDPNYRLLTPYNQLTISNKEKVIGYSERLLNHQIDKKSKDLI
                     DKPSQLYAYRVYESLSAGTGYSYFGDGNFDVVFYDEQLEYDFASWVFGDSMEPTYLNG
                     EVVLIKQNSFDYDGAIYAVEWDGQTYIKKVFREDEGLRLVSLNKKYSDKFAPYSEEPR
                     IIGKIIANFRPLEI"
     gene            36578..37648
                     /gene="xerS"
                     /locus_tag="VB649_000948"
     CDS             36578..37648
                     /gene="xerS"
                     /locus_tag="VB649_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEP1669907.1"
                     /translation="MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKE
                     YKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
                     LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLD
                     LKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEY
                     RGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSS
                     TQVTDLYTHIVNDEQKNALDNL"
     gene            38348..38830
                     /locus_tag="VB649_000949"
     CDS             38348..38830
                     /locus_tag="VB649_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEP1669908.1"
                     /translation="MPKRIRKALGVVGKLMSIVPDTTEIIGKTIDNSRPIIEKRMEQK
                     HEKEMQLRTIDDVINLPVDQAQAHLEQLGFVVATIPAKPHKKWLHSNLNEVVAMSPKS
                     GKYKIGSLIKLYYITVDVLEKSQDLLDQENLRTVERNQKIADTFESVKHIRFPFKKWR
                     "
     gene            38919..39971
                     /gene="citC"
                     /locus_tag="VB649_000950"
     CDS             38919..39971
                     /gene="citC"
                     /locus_tag="VB649_000950"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEP1669909.1"
                     /translation="MPYYTISKVFPSDKTTMASVKNLLHQEGIRLDAHLDYTCAIMNA
                     QNDVIATGSYFGNSLRCLCVSSAYQGEGLLNRIVSHLIDEEYALGNYHLFVYTKTSSA
                     AFFKDLGFTEIVHIDNHISFLENKKTGFQDYLMTLNKPEQTPGKVAAIVINANPFTLG
                     HQFLVEKAARENDWVHLFMVSEDRSLIPFSVRKRLIQEGLAHLDNVIYHETGPYLISQ
                     ATFPAYFQKEDNDVIKSQALLDTAIFLKITQTLQITKRYVGEEPTSRVTAIYNEIMAE
                     QLQQAGILLDILPRKAINQQQDPISASTARQALKDNDWDLLAKLLPKTSLDYFCSLEA
                     QPIIKKIQATSSVKHY"
     gene            complement(40081..41475)
                     /locus_tag="VB649_000951"
     CDS             complement(40081..41475)
                     /locus_tag="VB649_000951"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEP1669910.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRAIHKAVKKTKLQMLLRGQNLLGYRNYADDVVRSFV
                     QKSIENGIDIVRIFDALNDPRNLQTAVSATKKFGGHAQVAISYTISPVHTIDYFVELA
                     KAYQAIGADSICIKDMAGVLTPEIGYQLVKCIKENTTIPLEVHTHATSGISEMTYLKV
                     AEAGADIIDTAISSFSGGTSQPATESMAIALTDLGFDTGLDMQEVAKVAEYFNTIRDH
                     YREIGILNPKVKDTEPKTLIYQVPGGMLSNLLSQLTEQGLADKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNIISGERYKVVPNEIKDYVRGLYGQSPAPLAEGIKEKII
                     GDEAVITCRPADLIEPQMIYLHDEIAQYARSEEDVLSYASFPQQARDFLGRREDPFYD
                     VPVQEVTVQLDIQD"
     gene            complement(41490..42068)
                     /gene="citX"
                     /locus_tag="VB649_000952"
     CDS             complement(41490..42068)
                     /gene="citX"
                     /locus_tag="VB649_000952"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEP1669911.1"
                     /translation="MCKDTYFSGEAIQLSDMLRAREERALRQLHLLKEYPEGSLLSVT
                     MNIPGPIKTSPKLLEVFDIVIKAIQTALADDKICYQLRLLPTTGYEYYLITSLPSRYL
                     KLKMIALETELPIGRLMDLDVLVLQNDLPHSISRTVLGGSPRQCFICSKEAKVCGRLR
                     KHSVEEMQTAISKLLYSFFNKDNQSSSSDKTG"
     gene            complement(42061..43593)
                     /gene="citF"
                     /locus_tag="VB649_000953"
     CDS             complement(42061..43593)
                     /gene="citF"
                     /locus_tag="VB649_000953"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEP1669912.1"
                     /translation="MVTNKLGRDIPQPYADQYGVFEGELANIKQYDESSRRIKPVKPG
                     DSKLLGSVREAIEKTGLTDGMTISFHHHFREGDFIMNMVLEEIAKMGIKNLSIAPSSI
                     ANVHEPLIDHIKNGVVTNITSSGLRDKVGAAISEGLMENPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDAYGNVNGTKGKATCGSLGYAMIDAKYADQVVILTDNLVPYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITNSPYFKEGFSF
                     QTGTGGASLAVTRFMREAMIKENIKASFALGGITNAMVELLEEGLVEKILDVQDFDHP
                     SAVSLGKHADHYEIDANMYASPLSKGAVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEVGIAINP
                     NRQDLVDHFKSLNVPQFSIEELKEKAYAIVGTPERIQYGDKVVALIEYRDGSLMDVVY
                     NV"
     gene            complement(43596..44483)
                     /gene="citE"
                     /locus_tag="VB649_000954"
     CDS             complement(43596..44483)
                     /gene="citE"
                     /locus_tag="VB649_000954"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEP1669913.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSVMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSSVETVVRVNGLDSCGALDIEAVVLAGVNVIRLPKTETAQDII
                     DVEAVIERVERENGIEVGRTRMMAAIESAEGVLNARDIAKASKRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQNEVRMIKQLGFDG
                     KSVINPRQIPLVNEIYTPTKKEIDHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AERVIALATAAGVLSEEDI"
     gene            complement(44471..44779)
                     /gene="citD"
                     /locus_tag="VB649_000955"
     CDS             complement(44471..44779)
                     /gene="citD"
                     /locus_tag="VB649_000955"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEP1669914.1"
                     /translation="MDIKQTAVAGSLESSDLMITVSPNDEKTITITLDSSVEKQFGNH
                     IRQLIHQTLVNLKVTAAKVEAVDKGALDCTIQARTIAAVHRAAGIDQYDWKEIDSWNV
                     "
     gene            complement(44967..46088)
                     /locus_tag="VB649_000956"
     CDS             complement(44967..46088)
                     /locus_tag="VB649_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEP1669915.1"
                     /translation="MDTLIAGITSITIPQIVMMVIGALLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGSGVLTQVVNGVEQEGVFEALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLVGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRTTYKAENVSQMTKILFPIIITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQADLF
                     LNVQTLLIIVFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            complement(46133..46528)
                     /locus_tag="VB649_000957"
     CDS             complement(46133..46528)
                     /locus_tag="VB649_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEP1669916.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPAQAAAPAQPISTPVPVPTEA
                     SPQVEEAQAPQPVAAAGADAIPSPMPGTILKVLVAVGDQVTENQPLLILEAMKMENEI
                     VALSAGTITAIHVGPGQVVNPGDGLITIG"
     gene            complement(46585..46908)
                     /locus_tag="VB649_000958"
     CDS             complement(46585..46908)
                     /locus_tag="VB649_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669917.1"
                     /translation="MQFLQKWFKHSKKEKLKESSPLSTEIEPSENWEKIPAYIPADKS
                     DYKKVTLITSVIAAGDRPNSQFKVKRILKRNPEAITVSLIASSIAAGVYPESQFRVTS
                     IYCKR"
BASE COUNT        14779 a         8143 c         9362 g        14825 t
ORIGIN      
        1 aatggtatta ttgaaattat agtgaaaaca acggacaaaa atttattaat ttctgttatt
       61 gataatggtc cagggataac agatgaagaa aagaaaaaga tttttgatcg tttttatcga
      121 gttgacaaag ctagaacacg gcaaacaggt ggatttggct tggggttggc tttagctcag
      181 caaatcgtga tgtctttaaa aggaaatatt acagtaaagg ataatgatcc taaaggtagt
      241 atttttgaag tcaaactata agctaaaaag ggcgaccaat aaggtcagcc cttttaaagt
      301 tatttttaac tgtcaacgct ttattgtatt ttttgagttt ttaccgtata aaaaaactcc
      361 agctggagtt ttcattggat atttattagc caagttttgc agcaaggcgt gctttatcgc
      421 ggcttgcttt gtttttgtga atcaaacctt ttgattcagc tttatcgatg cttgaagaag
      481 cagcgcggaa aagctcttca gatgggttag cttcaaatgc tttgatagca gtacgcatag
      541 ctgatttttg tgctgagttt ttttcgtttg ctttaacgtt aagttcagcg cgtttaatag
      601 ctgatttaat atttgccaat gttttcacct ccaaattaat ctaactacat tattatatag
      661 aaaatatatg cgtttggcaa ccctttatca ctttttgagg taaatttcat caattttatg
      721 atcagcactt ttatgtaaaa ttaattcagc acggttacgt gtaggttcaa tgaatttttc
      781 aagattttct aaattaacgg ttttccaaac gttgcgcgca aatgctatag cctcagatcg
      841 aggtaattgt gcatattggg cataataatt atgagggtca cgttttgcta attttaaaat
      901 gcttagaaac cgttcaatgt accaggtttc gatgtgactg ctgtctgcat caatataaat
      961 agaaaaatca aagtaatcac tcatatataa acgattgttt tgttgatttt gaaaaacatt
     1021 aataccttcg acgataagga agtcagggtt attaaatgat tgtttttgat ttgggataat
     1081 atcgtaaata tcatgagaat agacgggtgc aaaagcagtt tgaccatttt tgatggaatc
     1141 tagaaaatct aagagaagtt ccatgttata agattctgga aatcctttac gatttaacag
     1201 tccttgttca ataagaaact gattaggata taaaaaacca tcagtcgtta ccagttcgac
     1261 ttgactattg gggtgcgttc gtgataataa aagttgtaaa agacgactag ttgttgattt
     1321 accaacagct actgaaccag aaattccaat aataaaaggt cttaattgaa tgtctttttt
     1381 tagaaaaagg cttttagaaa aagaaagatt ttcttgcgca attttgtaaa cctggatcag
     1441 attaattaat ggaaggtaga tatcaatgac atcgttaata ctgatgttat catttaagct
     1501 agtaatactt ttaagttcct cttgtgtgag gagagctttt gccttttgat gtaatgtttt
     1561 ccaagactct ctagaaattt tttcaaagtt aataaattca tttgacatgg tagctcctaa
     1621 tcatttgaca gtgcttacat tataccattt tagttaaaaa ataaataatt tttcgttagt
     1681 atttacacga aaattaatac aattaactca aaaaagccac acattcctag tacaattatc
     1741 ctgctatatt ctaacaaata gttaaagttc ggtttttatt tgtaatatag ataaaattgt
     1801 taaaaaacaa gcgtcttgta aaccatttca aagtatgata gaatgaaaaa gtaccttaaa
     1861 aagataggaa aaatgatgac aaagatgtat tatgatgaaa atccagatag cctacacgat
     1921 attcatgaag taaaagtaga gctgcttaat catcccttta cttttttgac ggattcaggt
     1981 gtcttttcaa agaaaatggt tgatttcggt agccaagtat tattaaagac actaaatttc
     2041 aaggagaacg aacgtgtact ggacttaggt tgcggctatg gccctcttgg gattagtcta
     2101 gccaaggttc aaagggtaga cgcaacctta gtggacatta ataatcgtgc tcttgattta
     2161 gctagaaaaa atgcaactaa taaccaagtg gcagtaacta tttttcaatc aaatatttat
     2221 gaaaatatta gtggccattt tgagcatatt attagtaatc ctcctattag agcaggaaag
     2281 agagtagttc atagtattat tgaaaaaagc atagattttt tagtggttaa tggtgactta
     2341 acgattgtga ttcaaaaaaa acaaggagct cctagcgcta aagcaaaaat ggcaactatt
     2401 tttggtaatg ttgagatatt aaggaaagat aaaggttatt atgtattaag aagtataaag
     2461 caagcctaat ttaaataatc aacaattgct catttaaatt aggtttgctt aaatagtaaa
     2521 gagttatttt taaattatag ataactaata ttatactagg gtagcccctc tactcgagta
     2581 acctttttta atgtatttta actgaaaaag gctttcataa ttttaaaaaa atgttaaaat
     2641 aggtgtataa caactgatta ccaagagatt attatcatta tcttctaagg tgtcattgtt
     2701 atggtgacaa tcaaccatac gctactaaag ataggtagcg ttcgatcaca ggttgatcaa
     2761 gtgattgaaa agtcaatatt tataatttta caaatatctg tatcaatcca tgttgaatag
     2821 tctatgcttc taaggtgtcg acgttaatgt actgacggga ccgttatagt ctttcttttt
     2881 ggagaaacgt cggatgccag tgaactagtt gaagttaaag atgttaattc aaacagtgct
     2941 gaagagattg atatcgtttt gaacggtcgt ttacttcaaa gcaaagaaat taccagtcta
     3001 tcggagatga tataagtgct aaagttagat cacgttaatt atctatcaag tcgggtgcat
     3061 atttcgttaa agtatctaca ggggtttcaa tagatgtagc tattatgaaa ggtgatgtta
     3121 aatggggact actgatttag ttagttgtgc tgtacaagct agtgagtatg cttatgtccc
     3181 ttactctcat tttccagtag gagcagcttt aaaaacaaaa gatggaacga tctatactgg
     3241 ctgtaatatt gaaaatgtta gttttggtct gacaaattgt ggagagcgaa cagctatatt
     3301 taaagccata tctgatggtc ataaagaatt ggttgaaatt gctatttatg gagaaactat
     3361 gcaacctgta tctccttgtg gggcttgtcg tcaggtaatg gcagaatttt ttgatccttc
     3421 ttctttagtc actttaattg ctaaaaatgg tcaaactgtt gaaatgactg ttggagattt
     3481 actcccctat tcttttacag atttaatata atctgcttta atttctgtta tctagccgtc
     3541 ttggctttat atttactttc agcaacttat ttgctagaaa tcttttttag gagggttcat
     3601 attcatgaac aagaaattta ttggtcttgg tttagcgtca gtggctgtgc tgagtttagc
     3661 tgcttgtggt aatcgtggtg cttctaaagg tggggcatca ggaaaaactg atttaaaagt
     3721 tgcaatggtt accgatactg gtggtgtaga tgacaaatca ttcaaccaat cagcatggga
     3781 aggcctgcaa tcttggggta aagaaatggg ccttcaaaaa ggaacaggtt tcgattattt
     3841 tcaatctaca agtgaatctg agtatgcaac taatctcgat acagcagttt caggagggta
     3901 tcaactgatt tatggtatcg gctttgcatt gaaagatgct attgctaaag cagctggaga
     3961 taatgaagga gttaagtttg ttattatcga tgatattatc gaaggaaaag ataatgtagc
     4021 cagtgttacc tttgccgacc atgaagctgc ttatcttgca ggaattgtag ctgcaaaaac
     4081 aacaaaaaca aaaacagttg gtttcgtggg cggtatggaa ggaactgtca taactcgatt
     4141 tgaaaaaggt tttgaagcag gagttaagtc tgttgacgat acaatccaag ttaaagttga
     4201 ttatgctgga tcatttggtg acgctgcaaa aggaaaaaca atcgcagcag ctcagtatgc
     4261 agcaggtgct gatgttattt accaggcagc aggaggcact ggagcaggtg tatttaatga
     4321 agcaaaagct attaatgaaa aacgtagtga agctgataaa gtttgggtta ttggtgttga
     4381 ccgtgatcaa aaagacgaag gaaaatacac ttctaaagat ggcaaagaag caaactttgt
     4441 acttgcatca tcaatcaaag aagttggtaa agctgttcag ttaatcaaca aacaagtagc
     4501 agataaaaaa ttccctggag gaaaaacaac tgtctatggt ctaaaagatg gtggtgttga
     4561 aatcgcaact acaaatgttt caaaagaagc tgttaaagct attaaagaag cgaaagcaaa
     4621 aattaaatct ggtgacatta aagttcctga aaaatagtgt ttaagaacaa gaagcgcgac
     4681 ctttgtcggt cgctcttttt aaactgagat aatttttatc tcagtaaagt ttgtgatagg
     4741 tgatagatca taggctttac tgaaataaaa gattgcattg aaaggaaatg atcctatgac
     4801 acagcatgtc attgaaatga gagaaatcac gaaaaaattt ggtgattttg ttgcaaatga
     4861 ccacattaac ttaaatgtca gaaaaggtga gattcatgcc ttattgggtg aaaatggggc
     4921 aggtaaatca actttgatga atatgctagc tggtctctta gagcctacta gtggagaaat
     4981 tgtcattaat gacaagccag ttcaaattga ttcgccatct aaatcagcta agcttggtat
     5041 cggaatggta catcaacatt tcatgttagt agaagccttc acggttgctg agaatattat
     5101 tttaggaaat gaagtagtaa aaaatgggtg cttagatctt aaccaagcat cgaaagatat
     5161 taaggtacta tccgaaaaat atggccttgc aatcaatcca tcagctaaag tttctgatat
     5221 ttcagtagga gcacaacaac gtgttgagat tttgaaaacc ttgtatcgtg gtgcagatat
     5281 tcttatcttt gatgagccaa ctgcagtttt aacacctgca gaaattaaag aattgatgac
     5341 tatcatgaag aatctcgtga aagaaggaaa atcaattatt ttaattaccc ataaactgga
     5401 cgagattcgt gctgtcgccg accgtgtcac agttattcgt cgtggtaaga gtatcgaaac
     5461 agttgatgtg gcaggagcaa cttcacaaga tttagctgag atgatggtgg gacgctcggt
     5521 ttcctttaca actagcaaaa aagctgctga accaaaagat gtggtcttat ccatcaaaaa
     5581 tcttgaagta gatgaaaata gagggattcc agcagttaag gggctatctc tagatgtccg
     5641 agctggtgaa attgtaggga ttgctggaat tgacggaaat ggtcaatctg agttaattca
     5701 agctattaca ggtttacgta aagtcaaatc tggaagtatc atgattaaaa acaatgaagt
     5761 cactcatttg tcttcacgca aaattactga gttatcagtg ggtcacgtgc cagaagatcg
     5821 tcatcgagat ggtttgatac tagatctttc tttagctgaa aatacagcct tacaaaccta
     5881 ttacaaacaa cctctaagtc aaaatggaat cttaaattat actaaaatta atgactatgc
     5941 tcgtcaatta atgaaagaat ttgatgttcg cggagccaat gagctagtac cagctagagg
     6001 attttctggt ggtaaccaac aaaaggccat tattgctcgt gaagtggacc gtgatccaga
     6061 tttacttatt gttagccaac caacacgtgg tcttgacgta ggagctattg aatatatcca
     6121 taagcgtttg attaaagaac gtgataaagg taaagctgtc ctcgttgtta gttttgaact
     6181 tgatgaaata ttgaatttat ctgatcgaat tgctgttatt catgatggta aaattcaagg
     6241 tatcgtattg ccagaaaata ccaataaaca agaattgggt attttaatgg caggtggttc
     6301 aattcataag gaggaaggtc atgtctaaaa atgcgcaaaa aattgctgta ccattaattt
     6361 ctgtcttgct aggattttta cttggcgcta ttattatggt tatctttggt tatgatccta
     6421 tctgggggta tgaaggttta ttccaaattg cctttggtag tgttaaaaat attggagaaa
     6481 tattccgttc aatggggcca ttgattttaa tagcgcttgg ctttactgtt gctagccgtg
     6541 caggcttctt taacgttggt ttgtctggac aggctttagc tggatggatt tcagcaggtt
     6601 ggtttgcact cttaaatcca gatatgcctc gtccattatt gattcttatg acagctctta
     6661 tcggaatgat tgctggtggt attgctggag ctattccagg gatacttcgt gcttatcttg
     6721 gtacaagtga agttatcgtt acgattatga tgaactacat cattttatat gtcggaaatg
     6781 ctattgttca acgtggttat cctgagagtg tcaaacaaag tattgattca actattcaag
     6841 ttagtgataa tgctagttat caaacgcatt ggttatcagc cctaactaat aactctcgta
     6901 ttaatattgg tattttcttt gccattattg ccattgccct aatctggttc ttgcttaaca
     6961 aaactacttt aggttttgag attcgttcag ttggtctcaa cccacatgct tcagaatacg
     7021 cagggatgtc atcaaaacgt actatcattt tatcaatgat tatctctgga gctctcgcag
     7081 gtcttggagg agtagttgaa ggtctaggaa cctttgaaaa tgtttttgta caaggatctt
     7141 ctttagcagt tggttttgac ggtatggcag ttagcttatt agcagcaaat tcaccgcttg
     7201 gaatattttt ctcatcattc ctatttggtg tcttaaatat tggtgctcca ggaatgaata
     7261 ttgcaggcat tccaccagaa cttgttaaag tagtaactgc atcaatcatt ttctttgttg
     7321 gttcacatta cctcattgaa cgttacatta ttcgccctaa aaaattagtg aaaggtggta
     7381 aataagatga gtttagtaac aatttttgcc ttattgatgt catctatgct tatttatgca
     7441 acaccactca ttttcacaag tattggagga actttctcag agcgctcagg cgttgttaat
     7501 gttggtttag aaggtatcat ggtcatggga gcgttctctg ggattgtttt caacttagag
     7561 tttgctgaaa catttggaaa agcaacgcct tggatagccg ttttagtcgg tggtattgtt
     7621 ggtttgattt tttctttgat tcacgctgta gcaaccatca actttcgagc tgaccacatt
     7681 gtcagtggta cagtgttgaa cttgttagca ccttcttttg ctgtcttctt ggttaaagct
     7741 atgtacggta agggacaaac agacaacatt caacaatctt ttgggaagtt tgatttccca
     7801 ggtttatcac aaattcctgt gattggtgat attttcttta aaaatactag ccttattggt
     7861 tacttcgcca ttgctttttc gttctttgct tggtttttgc tttataaaac caggtttggt
     7921 ctgcgtttac gatcagttgg ggaacaccct caggcagctg acacacttgg tattaacgtc
     7981 tatttgatga aatactatgg tgtgatgatc tcaggttttc ttggtggaat aggtggagct
     8041 gtttatgctc agtcaatctc cgttaacttt gctgtaacaa ctatcttagg tcctggattt
     8101 attgctttgg cagctatgat ctttggtaaa tggaatccag ttggcgccat gctatctagt
     8161 cttttctttg gcttatcgca aagtttagcc gttattggtg ctcaattacc attactagaa
     8221 aagattccaa cggtttactt acagattgca ccttatatgg taacgattat tattttagct
     8281 gctttctttg gtcaagcagt tgcaccaaaa gctgatggaa tcaactatat taaatctaaa
     8341 taacgttata ttagtaagcc tcttagtgag gtttaacagc actcctaaag caagatagtt
     8401 aggtctagct ttaagggtgc ttttttgggg acttaccgca agtttggatt gccagtcacc
     8461 atcacaatag aagcaagaat agactaaaaa gaactaagtc agcggcttag ttctttttgc
     8521 ttgtcttttg tttttactga tagctcttaa gttgttttag ccaacaaagg tattgatttc
     8581 tgtttcaatg ttagcaattt tttcttgagc gatgtcaaga gtatcaccta ttgtggcaat
     8641 atagaacttg atttttggtt cagttcctga agggcgaact gcaatccatg aatcatcagc
     8701 taacgtgtac ttcaaaacat tacttggagg agttgttaag ttagatattg ttccatcatt
     8761 tttagtagcg gtttgttttt ggaaatcttc taataataca atatcagtat tgttaaattg
     8821 ttttggacca ttttcacgga atttgtccat aatcttctta atttcagcag ctccatccac
     8881 acctgaaagt gttactgaaa tcgttttttc agcaaaatag ccatattctt tgtaaatttc
     8941 atcaatacca tctgcaagtg ttaaaccacg cgaacggtaa taagctgcga tctcagcaac
     9001 caaaagaact gcttgaatag cgtctttatc acggacaaat ggtttaataa gatatccgaa
     9061 gctttcttca aaaccaaaca tataggtgtg gttatgtttt tcttcaaact cttgaatttt
     9121 ctcagcgatg aatttgaatc cagttaaaac gttaaacatt gtagcgccat aactttcggc
     9181 aatttttgtt actaattctg ttgatacgat tgatttagcg agagcagcat tttctggaag
     9241 tgttcctgct gttttatgag cttccaggat gtatttcgca ataatcgctc caatttgatt
     9301 tccagaaaga tttttataag aaccatctgg ttggcgaatt tcaacgccta ggcggtctgc
     9361 atcaggatcg gtagctacta agacatctgc atcaacttct cgtccgagtt cttcagcaag
     9421 agcaaaggca gcttggcttt cagggttagg cgatttaaca gtagaaaagt ctggatctgc
     9481 cttagcttgt gattctacta caacaacaga ttcaaaaccg gcttgagcaa gggcacggcg
     9541 tgtcaacatc tcaccagttc cgtggagagg agtatagaca attttcatgt cttttccaaa
     9601 gttattgatt aaatcttgat tgatattaac atctttaacc tctctaagat attccatatc
     9661 aacatcttca ccgataactt gaataagacc tgctgatttg ctttcatcta aatcagcaag
     9721 ttcaactgca aatggatttt caatagcacg gataaagtct gttagtgcat cagcatcagc
     9781 tggtggtagt tgacctccgt cttgtccata gactttataa ccattgaaag gtgctggatt
     9841 gtggcttgca gtaaccataa taccagcata ggcatttaaa tggcgaacag caaaagaaag
     9901 ttctggtgtt ggacgaagag cttcaaatac gtaagattta attccatgct gtgccaagac
     9961 ctgtgcagat tcaaaagcaa attctggaga gaagtggcgc gaatcataag cgatggctac
    10021 accacgtttt ttagcttcct cttccttagt ttcgattaat tttgctaatc cttcggttgc
    10081 ttgacggaca acataaatat taatacgatt tgtaccagca ccaatataac cacgcatacc
    10141 agcagtacca aattctaagt ttgtgtaaaa agcatcttct tttgtttttt catccattga
    10201 tagtaattct tgacgaagat agtcaggaag ctgctcaaaa tctaaccatt tttgaaaatt
    10261 ttctgtgtaa gtcattgaaa tactccttca atatttataa acgctttcat tatatcattt
    10321 tgaaggaaaa aaaacactaa ttatttgcag ctgtttacaa aactttttcc atattttcaa
    10381 gtagctaatg taagaaagtt aaaataacca agtttttaaa agagaaaaac tcggttattg
    10441 tgaaagctaa ttaccttttt agtcttgata gtgttggaat aagtacaaag gtaataatag
    10501 ctgagatgat catctcaaca atagcgtttg atgagatgat ggctgttagt agtgctttaa
    10561 tatttccatc aaaaactgtc gcgaaaaaaa taaatatccc agataataca aatatagtat
    10621 ttgttagaga accaatgata ccggagacta ttaaaccaaa ctgattagga atcaatttat
    10681 agcaataata aggggtaata ccaatcaaaa tacgtgggat aatagcaatt attaaagaag
    10741 cgaaagttcc atgatcgaca aaaggtgaaa agagataatt tgtaggcagt agaatgatgg
    10801 tatttgtaat gacacttata atccccatta atcctcctaa aatagcacct attcttggtc
    10861 catataagac agaagcaata ataactggga tatggacaag tgttggtttg attggaatag
    10921 gccaaatatt aaagacaaga ctgctcacaa aatgaatgac taacatgatg gcaaaaaaga
    10981 tagcaatacg agaaatatct gctgatttac ggtgattcat tttactctcc aaaaaatata
    11041 atacttaatt ctaaaaagtg atcagaaaaa cgactgttta aagtttccaa atcgtatcaa
    11101 tagtagctaa gataacatca atatcagcca aagcaccagg tcctttatct ccacaggcta
    11161 ataagctaga ttttggagga atttctgtaa accctattgt cgataagcgt ttaatatttt
    11221 cttgggtaat agggttttga tacattttgg tattcatggc tggggctatt aattttggtg
    11281 tggtagctgg tagggcaagc gcaacacttg ttacaatatt atcagcgaat ccatatgcta
    11341 gatgagcaat agtattagca gaggcaggtg cgacaataaa taaatctgtg cgttttgcta
    11401 attcgatatg gttgataact tttgggtcat gctcatccat aacatctaaa tgaatagcat
    11461 tttttgataa cacttgcagg gttaatggtg taataaattg tgtagcagcc tgagtcatta
    11521 tgatgtgaac atcatagcca attttagtta attgactcgt aagatctgct gctttatagg
    11581 cagatatact accagaaaca gctaaggtaa tatgtttagt catgtttggt catcctttca
    11641 tataataagt cagcaattgc ctctttggta tctgcagatg caacttcgtt attggatatc
    11701 aaaagagcct tgtgcatacc tgtttggata tcaactaaat cattggcgag aatataatca
    11761 gcatggtttt tagctagact tgctctggct actttaatta actcttcttg aggcacatta
    11821 actagaagtt taaagccgac tagtttaata ttaggattcc actgtttaac ataagagata
    11881 actttgggtg tttttttcaa aaaaagaacc tgataatcag atgcagatga gattttcggc
    11941 tcactgttat gttcacatag aaaacaatta aggttatcag cttgagagac ttgttccaaa
    12001 tcagtcatgt agactggagt atagtcagaa acagccatac tatgaattag aatgtcatgg
    12061 tgaggaacct gatctttgag tgcagccatt aagtcgttaa ctgtttccac ttcaataatc
    12121 cttaggtgct catttggcag gagtttagtg gctgttttag tagtgactag ggtaacgtca
    12181 tgatgatatt gtaaaaatcg ctctgtgatt aattttccaa gttgcccagt tgagtgatta
    12241 gtgatacctc gtactgcatc tataggttca gttgttccac ctgatgttat tattaatttc
    12301 atagtcatat tttatcaaaa aaggagctga tagtaaacgg aagataatga cgccagacat
    12361 tgtcttgcgt ttgtattaat atggaatagt aatagatttc tagtaattaa aacgaagttc
    12421 tggaaagcaa gacactatag tagctaaaat ctaaatttta aggtaaaata gggcaagcgg
    12481 tttcaagtgt gaaaggaaga attgtgataa ctattagaga tttagcgtca ctgccgattt
    12541 ttgtttacgg tgatggaaat aaaaaagttc caggagcttt gagtcctttt gtgtggacag
    12601 aggtgttttt aaaaactatc aatcaagaac ctaatcaact gatcttacat atttggccga
    12661 tgacaagaac agttatatta ggaatgttag atagacagct tccctacttt gagctggcta
    12721 aaaaagagat tggcaataat ggttatgttc ctgttactcg taatattggc ggtttggctg
    12781 ttgtcgctga tgatgggatt ttgaattttt cgcttgttat tccagaccat ttttcggaat
    12841 ctatcagtat tagtaatgct tatttaataa tggttgatgt cattagagag agtttttcgg
    12901 attattatca gcgtattgaa tatcacgaaa ttaaaaattc ttattgccct ggtaattttg
    12961 atcttagtat tgcaggccgc aagtttgcag gtatcgccca gcgtcgtatt aaaaagggaa
    13021 ttgttgtgtc tatttacttg agcgtttgtg gggatcaagc agcgcgtggt caactcatca
    13081 aggcttttta tgaggctgga acacaaggag aagttaccaa ggttaattac cctcaaattg
    13141 atccagaatg catggcaact ctttcagaac tccttgagac gccttttaca gtggcagaag
    13201 tccttgaacg tcttcgattg accttgcgac agcttggctt ttccctcacg gaaaaaagtc
    13261 cagatcaagc tttactgact aattttgatg ctgtctatga acggatgcag ctagaagtcg
    13321 ttagaaagga aggcaaatga aagaaagatt tagtccttta tttgagcctt tgactttgcc
    13381 aaatgggagt caattggata atcgctttgt tttgtctcct atggtgacca actcatccac
    13441 aaaagacggt tatgtcaccc aagatgatat atcctatgct ttgagacgag cagcttctgc
    13501 ccctctacaa attacaggag cggcctatgt ggatccttat ggtcaattgt ttgaatatgg
    13561 ttttagtgtt acaaaagatg ccgatatttc tggcttgaaa gagctagctc aagcgatgaa
    13621 ggcaaaggga gctaaagctg tcttacaact gacccacgct ggccggtttg ctagccatgc
    13681 cttgactaaa tatggctttg tctatgggcc tagttacatg cagttgagat ctccccaacc
    13741 tcatgaagtc aaacctttaa caggtcagca aatagaggaa ttgattgcag cttacgctca
    13801 ggccactcgg cgggcaattc aagcaggctt tgatggtgtg gaagtatctt cggcgcagcg
    13861 cttattgatt caaacgttct tttcgacttt ttcgaacaag aggacagata gttatggttg
    13921 tcaaacactt tttaatcgct ctaagttaac tttagctgtt ttgcaagctg ttcaacaggt
    13981 gattaaacaa gaagctcctg atgggtttat ttttggattt cgtgctacac cagaagaaac
    14041 taggggaaat gatattggtt atagtattga cgagtttttg cagttgatgg attgggtact
    14101 taatgttgca aaacttgatt atttagcgat agcaagttgg ggccgtcatg tatttcgaaa
    14161 tactgttcgt tctcctggcc cttattatgg aaggcgagtt aatcaggtag ttagagatta
    14221 tttaagaaat aagctacctg ttatggctac agggggaatg aacacacctg acaaagctat
    14281 tgaagcacta gctcatgctg attttattgg agtatctaca ccttttgtcg tggatccaga
    14341 atttgctcat aaaatcaaag aagggtgtga agagagtatt catttaagga ttcgacctgc
    14401 tgatttgaaa agtttagcga ttcctcaggc ttctttcaaa gatatcgtac ctttgatgga
    14461 ctacggggaa tcattgccta aagaatcaag aactttattt cgtagtctta ctcacaatta
    14521 taaggagatt aaatgaaagt cagtattctt gattatgggg tgattgataa agaaaaaaca
    14581 ccccaagaag ctttattaga aacgcgctgc ttagcacaag tagccgacaa acttggtttt
    14641 caccgttttt gggtagcaga gcatcataat atttatgcct ttgcaataag cagtccagag
    14701 ctgttgatga tgcatttagc agatcatacc aaacagattc ggataggttc aggaggtatt
    14761 atgcctctac attatagtag ctttaagatt gcagaatgga taatgacttt agaggccttg
    14821 caccctaatc ggattgattt aggtattggc aactctttag gaactacgtt agttcaaaga
    14881 gctctatcaa gtatccattg caaagacagc tatagtcagg ttgtcacaga attataccag
    14941 tatcttaatc ctgatcattt gtcaccacta ccgatttttg ttaaccctag gggtaatact
    15001 taccctcaga tttggacgct aagcaatagt ttggagacag cagaactggc tggtcaatta
    15061 ggtttaggct atacctttgg tattttcccc tatataccaa aagatcctat aacagaagct
    15121 aaaagagtat cggcacatta tagaaaggct tttaggcctt caaagctatt aaaaatcccc
    15181 aagttaatat tagcagtttt tattgtcctt tctgataccg acgaggaagc agaagctttg
    15241 gctaaaccgt tggacatttg gatgcttggt cagcaagatt ttaatgaatt taagacctac
    15301 cctgatgttg aggaggctag aaactatcac ttaacagaga aacaaagaga agccattgca
    15361 gcaaatcgta gtcgcatggt tattggatca cctcacacag tcaagaaaca attggatagg
    15421 ctgatagaag cttgtcaagc tgacgaatta ttagccatcc ccttagttcc tgaatttgcc
    15481 aatagacaac gaaccttaga gctgctagca gacttatacg tgaccattta accttaccaa
    15541 aaacaattcc ctaaactgaa aggaaagaaa caatgaaaaa aattgcaaat tacttattaa
    15601 ttgagaaaac agatgaccgc tataccatta gcatgacacc agaattacaa gacgatattg
    15661 gtactattgg ttacgctgaa tttacggata acgaccacct tgccgttgat gacattatct
    15721 taaatctaga ggcttctaag accgtcatgt ctgtcttgtc accattggct ggggcagttg
    15781 ttgagcgcaa tgaggcagcc acactaacac caaccctttt gaattcagaa aaagctgagg
    15841 aaaattggat tgttgtgcta acagatgttg atcaagcagc ttttgatgcc ttagaagatg
    15901 cctagttcat ttgatttatt aggggaaatg attggtctgt tgcaaacaga gccgcttact
    15961 agttcttggg cctgtccctt gcctaatgct ttaacaaagc gacaagactt gtggcgggcg
    16021 ctcattaacc agcgccctgc tttgccctta tcaaaagatt acttgaatct ggaagatgct
    16081 tatctagatg attggcgtgc ttcttttgtt cctgtatcag tcaaggattg ccaaaaaact
    16141 aattatacca gtctttttct ttaccatggg gatattaggt accttgctgt ggatgctatt
    16201 gtcaacgctg ctaatagtga gttattggga tgttttattc ctaaccatgg ctgtattgat
    16261 aatgcgattc atacgtttgc cggaagtcgt ttacgcttag cttgtcaggc aatcatgact
    16321 gaacaaggcc gtaaggaagc cattggccaa gcaaagctta ccagtgctta tcatctacca
    16381 gcttcttata ttattcatac cgtagggcca agaattacca aaggacaaca cgtttctcct
    16441 attcgagctg atttgttagc acgttgttat cgttctagtc ttgatttggc ggttaaagca
    16501 ggattgacta gcctagcttt ttgctctatt tcaacaggag aatttggctt tcctaaaaaa
    16561 gaagccgctc agattgctat taagacagtt ttaaaatggc aagcagaaca tccagaatct
    16621 aagaccttaa ctatcatttt taataccttt acatcagaag acaaggcctt atacgacact
    16681 tatttgcaaa aggagaataa ctgtgagtaa ttggacaacc tatcctcaga aaaacctcac
    16741 ccaggcagaa caactggccc aattaatcaa agaagcagat gcacttgtag ttggtattgg
    16801 agctggcatg tctgcagctg atggttttac ttatatcggg ccgcgttttg agacggcatt
    16861 cccagatttt attgctaagt atcagttttt ggatatgctg caagctagtc tttttgattt
    16921 tgaagattgg caagaatatt gggcttttca aagtcgcttt gtcgctttga attatcttga
    16981 tcagcccgta ggccagtctt atcttgattt aaaagagatt ttggaaacca aagactatca
    17041 tattattact actaatgctg ataatgcttt ttgggtggct ggttatgatc ctcataacat
    17101 ttttcacatt caaggggaat atggtttgtg gcaatgtagc cagcactgcc atcagcaaac
    17161 ttataaggac gatacggtca tccgtcaaat gatcgcagag caaaaaaaca tgaaagtccc
    17221 aggtcaactg attcctcatt gccctgaatg tgaggcgcct tttgaaatca ataagcgtaa
    17281 tgaagaaaaa ggaatggttg aagatgctga ctttcatgcc caaaaagcac gttatgaggc
    17341 ttttttatca gaacataaag agggtaaagt gctttatcta gaaattggtg tgggacatac
    17401 gacgcctcag tttatcaaac accccttttg gaaacgtgtc tcagaaaacc ctaatgcctt
    17461 attcgttacc ttgaatcaca aacattaccg catccctctg tcaataaggc gacaaagcct
    17521 agaactgaca gaacacattg cacaattgat tagcgccaca aaaaccattt accaaaaatc
    17581 gtaaccaaag ccaatagacg gttaattaag agatagagaa ggagactaac atgtacctta
    17641 ttgaaccgat tcgtaacggt aaacgtatca ccgatggagc tgttgctcta gccatgcaag
    17701 tttatgttca agaaaatcta tttttagatg atgatatttt atttccctac tattgtgatc
    17761 ccaaagttga aattggaaaa ttccagaatg cagttgtaga aactaatcaa gagtatttaa
    17821 aagagcatca tatccctgtt gttcgcagag atactggcgg tggtgccgtt tatgtagatt
    17881 ctggtgctgt taatatttgc tacttgatta atgataatgg tatttttggt gattttaaaa
    17941 gaacctatca gcccgctatt gaagcccttc atcatttggg agcaacaggg gttgaaatgt
    18001 ctggacggaa tgacttggtt attgatggga aaaaggtatc tggcgctgcg atgactattg
    18061 ctaatggccg tgtttatggg ggatattccc ttttgctaga tgtggacttt gaagccatgg
    18121 aaaaagcatt aaaacctaat cgcaaaaaaa ttgaatcaaa aggcatcagg tcagttcgta
    18181 gtcgcgttgg aaacatcaga gaacatttag caccacaata ccaaggtatt acgattgaag
    18241 agttcaaaga tttaatggtt tgccaattgt tacagattga gacgattagc caagctaagc
    18301 gttatgattt atcggaaaaa gactggcaac aaattgatgc tttaacagag cgtaaatatc
    18361 acaattggga atggaattat ggcaacgcgc ctcaataccg ttaccataga gatggccgtt
    18421 ttaccggtgg aacagtagat attcatttag atattaaaaa aggctatatt gcagcttgtc
    18481 gcatttacgg agattttttt ggcaaggcag acattgcaga acttgaaggt cacttgatag
    18541 gaacacgaat ggaaaaagag gatgtcttag ctaccctcaa tgcaattgat ttagcccctt
    18601 atttaggtgc gattacagca gaagaattag gagatttgat attttcttga taaaaaagat
    18661 acctcagacc ggtaaagtgc gattaaaaac gaacaataat cgtttcaatt caaataaatg
    18721 tacgtatgat atgaattgtg atataatgac gtcattacgt aaaattgagg agtcatcatg
    18781 aaatcagata tcgaaattgc ccaaagtgtc gccctacaac caatcactga cattgttaaa
    18841 aaagttggaa tagacggcga tgacattgag ctttatggca aatataaggc taaattgtct
    18901 tttgagaaaa tgaaagctgt cgaagctaat gagcctggaa aattaatctt ggtaactgct
    18961 attaacccta ctccagcggg agaaggaaaa tcaaccatgt ctattggatt ggcagatgcc
    19021 ttaaatcaaa tgggaaaaaa aaccatgctt gccttacgtg aaccctccct tggtcctgtt
    19081 atggggatta aaggcggggc agcaggtggt ggttatgccc aagtattgcc tatggaagac
    19141 attaatcttc actttactgg tgacatgcat gccattacaa ctgctaataa tgcattatct
    19201 gctttgattg acaatcattt gcagcaagga aacgatttag gaattgatcc tcgccgcatt
    19261 atttggaagc gcgtgttgga ccttaatgat cgcgctcttc gtcaggtaat tgttggctta
    19321 ggtagtccag tgaatggtgt gccacgcgaa gatgggtttg atatcacagt agcttctgaa
    19381 atcatggcaa ttttatgttt ggcaactgac ttaaaagatc taaagaaacg tcttgctgat
    19441 atcgtcgtgg cttataccta tgatcgtaag cctgtctatg tgcgtgactt gaaggttgaa
    19501 ggagcattga cattaattct aaaagatgct atcaagccaa acttggtgca gactatttat
    19561 ggaacatcag ctcttattca tggggggcca tttgctaata ttgctcatgg ttgtaattct
    19621 gtccttgcta cctcaacagc tttgcgatta gcagattaca ctgttaccga agcaggattc
    19681 ggggccgacc taggagctga aaaattccta aatatcaaag tacctaatct tcctaaagca
    19741 ccagatgcta ttgtcattgt tgcaaccttg cgcgccctta aaatgcatgg aggtgtcgcc
    19801 aaatcagatt tagccgctga aaattgtgag gctgttcgct taggatttgc caacttaaaa
    19861 cgtcacgtgg aaaacatgcg ccaattcaaa gttccagttg tggtggctat caatgaattt
    19921 gtagcagata ccgaggctga aattgctacc ttaaaagcgc tttgtgaaga gattaaggtt
    19981 ccagtagaat tagccagtgt ttgggcaaat ggagctgagg gaggcttagc attagctaaa
    20041 acagtggttc gtgtgattga tcaagaagct gctgactaca aacgtctcta ttcagatgag
    20101 gatactttgg aagaaaaagt gatcaatatc gttacccaga tttatggtgg caaagctgtt
    20161 caatttggtc ccaaggccaa aacacaattg aagcagttcg cagaattcgg ttgggataaa
    20221 ttgcctgttt gtatggctaa gacccaatac agtttttcag ataacccatc cttgcttgga
    20281 gcgccaaccg attttgacat taccattcgt gaatttgttc ctaaaacagg agcaggtttt
    20341 attgttggtt taacaggtga tgtgatgacc atgcctggtt tgcctaaagt tccagctgcc
    20401 atggcaatgg acgtagcaga aaatggcaca gccctcggtc tcttttagga aaaattgctc
    20461 gaataattcg agcaagcgct cctttcttcc cgctttactg tgatataata aggtaaatga
    20521 gattttggag ggatgattat caaaaagaaa gcaaaagtaa aatatttgct ccataaaggg
    20581 aaacatggat ttttaagagg aatttttagt agaacaacaa tcattgtatt attaattatt
    20641 ttgcaattag ttttcttatt tcaatcttat gcctggatgg agcagtaccg tgtttggata
    20701 acgattcttg aaagtgtctt tgctattact attgttttat atttagttaa tagtgatatg
    20761 gatgctattt caagaatgac gtggttaatt ttgattatga ttgctccatt actagggtca
    20821 ctgtttttaa tttatacaaa attggattgg ggttacagag ggctaaaaca aagaataaat
    20881 catcttgtag atctgtctgc accttacctt agcgatgatg acgctatatt agaggtatta
    20941 aaggatagca catcaaccac atatcattta gtacagtact tagaaagaag tcgtggcaac
    21001 tttccgattt ataataatac aagggtaact tacttcccaa caggtgaaac tttttttgat
    21061 agtttaaaag aacagttatt cttagctaaa aagtacattt ttcttgaatt ttttattatt
    21121 gcagaaggcc aaatgtgggg agaaatcctt agtattctag aaaaaaaagt cagtgaaggt
    21181 gtagaagtta gggtgttgtt tgatggcatg aacgaactat caacgctatc atcagattac
    21241 gccaagagat tagaacaaat agggattaaa gctaaatcat ttttaccgat ttcacccttt
    21301 atctctacct attacaatta tcgagatcac cgaaaaattg tcgttattga tggggaggta
    21361 tcattcactg gaggtattaa tctagcagat gagtacatta atgaagtaga gcgttttggc
    21421 cgctggaaag atgctggttt aatgcttgag ggtgaagcaa cagacagctt tttaattttg
    21481 tttttacaaa tgtggtctat cacagaaaaa gaactgatta ttgatcctta tctttcagat
    21541 cattctttaa aacttccttc agatggctat gttattccct acggtgattc cccgcttgat
    21601 actgataaaa taggtaaaaa tgtttatata gacattttaa atcatgctaa agagtacgtt
    21661 tatatcatga caccttacct tattttagat agcgagatgg aacacgcttt acgatttgca
    21721 tcagaacgtg gagtagatat ccgaattatt atgccaggag tgccagataa gggggtacca
    21781 tatgccttag ctaaaaccta ttataaagct ttgatgactt ctggagtaaa aatttatgag
    21841 tatcaaccag ggttcgttca ttcaaaggta tttatctctg ataatacaaa agcagttgtc
    21901 ggaacaatta acttagacta tcgtagcctt tatcatcatt ttgaatgcgc gacttattta
    21961 tatcgtgtgt cagttattgc tgatattgtg aatgacttta atgaagctca aaagcaatca
    22021 ctattgatga catcagatca tttgaagcaa cgtccttggt atcaaaaatt gataggatta
    22081 ttagtacgaa caattgcccc tctcttgtaa ttttcgtaaa atatgttata atatctgtat
    22141 gcgatgagtc gattgtgact gcaaagtcac ttttgcgcag gggaggtcat taaggcggga
    22201 agccgacttt gataatctgt gtgaaccatt ttatcacaat cttatttatt aagaatgccc
    22261 cttggattga gatattctca atcctttttt aattttatta tcttagttaa aattcagaat
    22321 gtatcagtga ttattgtgtt tcaaagtaag aaagtagttt tttgggtatg agtgctatga
    22381 cttgacaaat gctaataaca tttgcataat gtaattagag atgaaaactt atgaaaagag
    22441 atgatcttat gcaaattatt aagcgtgatg gccacgttgc tgattttgat ccagataaaa
    22501 tttatcaagc aattattaaa gcagcaagga cggtctatgt tattgatgac acgtggcgac
    22561 aaaacttaac acatgtcact aaaaaagtag ttattgattt agaagaagca catgtagaac
    22621 gtcctactat caatatggtc caatcccttg tggagaatcg tttgatggat gctggatata
    22681 ttaccattgc agaacattac atttcttatc gtcttcagcg agatttagag cgtaatggct
    22741 atggtgataa gattgtggtt cacttgcgtt ttgaacaaat aaaataaaaa cgcttccaat
    22801 ggcattttag tgtctttgag gggataaggt ttaaatacct aacagataaa aatctgttag
    22861 gtattttttt tgctactatt aggtgtattc tatattacat agaacttaag cattcaagct
    22921 ttagtttaac tttctgttta ttttttgcta cattttggaa actcccctcc tttcttagtt
    22981 gaggtgaata aacttttatt tgataaatca tatccttagt cttaatgaaa cagtctagga
    23041 taatactact tcgaagtgac agctagtagt ttccaatttt taagtagtct aaaatgatgt
    23101 ttttttaatt tcaaaaccat gctttcgttt gttataaaaa ccgatcttct atagttagat
    23161 tttttatcca ggcattgaag attggggcaa ctatccaatt agagatttta taatacttat
    23221 ttatccccat tttttatatt aatggtacga agaaaagtta gttgctcttt ccacaagtat
    23281 ttttgattag cgagtttaat ttgctttgta tttgttgatt gatagcaata gagagatagc
    23341 gtttttttcc agttattatt attctatcag atttatctaa tgtaaagttt ctataagagt
    23401 ctgatgtcgt gtaatcaatc actaaatgag taggggttag ttgatagtga atatcagggc
    23461 aattttgttt taaaaagaga gccaattgac gttcccgctg ttttagataa cgcttaataa
    23521 agcgaagatt tttttgaaac atcccatttt ctaaataaag agctaatgct ttttgcatta
    23581 gtaagttcgt gtctaaatca atcagtgatt tttgggttaa aaaatgaggt tttaaacctg
    23641 acggtaaaac tagagctccg atacggagtg caggaaaaac actcattgaa aaagatttta
    23701 ggtagatgat tcggtgatga gtgtcataat aatgaattgg tggctcttta agtttcacaa
    23761 aatctcctaa ataatcatct tctaaaatat aaacctggta tcgttgtgct agacgaacaa
    23821 tagcttcctt ttccttagta ctataagaaa gtcccagagg atgtgaaaat cgtgaaatcg
    23881 tgtaaaaaaa tttaatatcg ccagtttgaa ataaagattc taagagttct aaatcaaggc
    23941 cattaaagtg tctagagata gtttgatagg gtaatcctaa ctgagcaaca atagcttcca
    24001 tccgatgata agtaggcttt tcaaggagaa ttgttttgcc cgcattagga aaaggcattt
    24061 gtgataaaat ataaagcgct tgttgcgtcc cagaggtgat taatagttgg tctttgttac
    24121 tgtaaacact attttcagct aagtaaagaa gcaaagcttc ccttagttct tctagtcctt
    24181 cggttttgtg ataataatga aagaggtatt tgtctttagc acttaaagcc tcatttaagc
    24241 agagtcggaa atcttcataa gccatattat tataatcttc aagacttaga ttaagaacat
    24301 tatcgggcat gcttacgtta cccaaaacat aataaccact tttaggaaca gcataaatta
    24361 agtgacgata ttttaattct aaaagagccc gctgaacagt atctttgcta caatgataaa
    24421 ccttacttaa taccctaatt gaaggtagct tgtccccttt ttttagtcgc tgtttctgga
    24481 tatcttgttc gatattggaa atgattgttt gatattttgt tgtcataaat tgtccccata
    24541 cagttaagtg ttataactat tgtatcttat gcctcttttt cttacaatag ttattataga
    24601 aaagaggtaa tagctatgaa acggattatt gtggcaaatg atctggttgg tgttggtaag
    24661 gtagctttgt ctgctagtat tcctttaatg gcttcttgtt tgttagagca agttttatta
    24721 ccaacttgcc ttttatcaag ccatactggc ggaggacaga accctgtgaa gcatactaca
    24781 tcaagtatat tagacgtttt tttaacagat tgggacaaca aaagaattaa gtttgacggc
    24841 atctttatag gttattttac gacaacaaga gatgggcaaa agctactaga atggctttca
    24901 agaaagcaac ttcccttaat tttagatcca attatggcag ataatggaaa actttatcaa
    24961 ggcttcagtc aaaaacatat agatattatg ataaaactta ctcaaaaagc tgagcttgtt
    25021 ttacctaata ttagtgaggc ttgtctatta acacaaacag cttatttagt aaaaaattat
    25081 gatgaagaag atattagaca ggtggctaga aaattagcta agcttggacc taaacaggtt
    25141 gtcattagcg gaatctcttt tgaggagggc agcattggtt ttgcttacta tcagtcagat
    25201 tcagatcaat taacattcca ttttgggaag caattccctt accatttcta tggtacagga
    25261 gatatagcat cagctattat aacagcagga ttctattatc agctaccact aacacaaatt
    25321 ctagatcttg ttgtttcatt tcttgaaaaa gtattgcaaa atacccttac attaaaaaga
    25381 gatttaatct taggtgttgc ttatgaatct catttaaatt acttaactaa atcgtttaaa
    25441 aagttgttgg aggaaaaaaa tgtcatctca aaaattagct aattatattg aattgagtat
    25501 gtatgccgct ttaattttta tttcagtaca agtgttgcgt atccctatcg gtatgcagtt
    25561 tattcatctt ggcaatgcat tagttgttat tgcagtcttg atctatggta gtaaaaaagg
    25621 agctctagtt gctagtcttg gtttagggat ctttgatgtt ttgaacggct atgcttcagt
    25681 cgtttggata actatcttag aatccttggc tatttgttta attttgcatt tggtatatga
    25741 aagagctatg caatctagta aaaaaccaaa agccattata acaataacag ttattgctgc
    25801 attgtcaaaa ttaactatta accttataaa atacttactg ttagcttata taggtactca
    25861 gctaccactt tcggtatctt tttgggtagc tcttggaaaa attggtggta gtttcggaac
    25921 atcttttgtg actttagttg ctgttcctct tttgtatcct gttatcaaaa acttaaaaga
    25981 aaaggttata atcggacaag caaaaagagg tttttgatac aagtacctta tcgataaaaa
    26041 agcaaggtac acttttagtc aaatattgac aaaaggttac aattttgcca taatgaaata
    26101 actataaagc cgttttgacg gcttttttga tgacagttaa ggaagaaacg atgagtattt
    26161 tagaagttaa gcagttgagt cacggttttg gggatcgggc tatttttgaa aatgtgtcat
    26221 ttcgcctctt aaaaggtgaa catattggac tagttggagc aaatggtgaa ggaaaatcaa
    26281 cctttatgag tatagtcaca ggacatttac agcctgatga aggaaaagta gagtggtcga
    26341 agtatgtcac tgcaggttac ctggatcaac atacagtgtt ggaatcagga caaaccgttc
    26401 gtgatgtctt gcgaactgct tttgatgagt tatttaagac cgagaatcgt attaatgaga
    26461 tttacgcgtc aatggcagat gataaagctg atattgctgt tttgatggaa gaagtaggtg
    26521 agcttcaaga tcgtttagaa agtcgtgatt tctatacttt ggatgctaag attgatgaag
    26581 tagcgcgtgc gcttggtgtt atggattttg gaatggagtc agatgttaca tccttatcag
    26641 gtgggcaacg aacaaaggtt ttattagcca aattactatt agaaaaacct gatattctgc
    26701 tattagatga accaactaac catttggatg ctgagcatat tgaatggtta aaacgctatt
    26761 tacaacatta tgaaaatgct tttgtgttga tttcgcatga tatttctttc ttaaatgatg
    26821 tgattaatat tgtttaccat gttgaaaatc aaagtttagt tcgctatact ggggattatt
    26881 accaatttca agctgtttat gagatgaaac aatctcaact tgaagcagcc tatgaacgtc
    26941 aacaaaaaga gattgctaac ttgcaggatt ttgtcaaccg aaataaggct cgggtagcga
    27001 cacgtaacat ggcaatgtct cgccaaaaaa aacttgataa gatggatata attgaacttc
    27061 aagctgagaa accaaaacca aattttgaat ttaagcaagc tagaactccc agtcgattca
    27121 tttttcaaac aaaaaatctt gtgattggtt atgattaccc attgaccaaa gaacccttaa
    27181 atataacgtt tgaaagaaac caaaaaattg ctattgttgg ggccaacggt attggaaaat
    27241 ctactttgct aaaaagttta ttaggtgtta tcgagccttt agaaggtcat attgtcacag
    27301 gggatttttt agaagttggc tactttgaac aagaagtgac aggtgttaac cgacaaactc
    27361 cgctagaagt agtttgggat gcttttcctg ccttaaatca ggcagaagtt cgagcggcac
    27421 tagctcgttg cggactaaca tcaaaacata ttgaaagtca aattcaagta ctttcgggtg
    27481 gtgaacaagc aaaagttcgt ttttgtttgt tgatgaatcg tgaaaataac gtgcttattt
    27541 tagacgaacc aacaaatcat cttgatattg atgctaaaaa tgagctcaaa cgtgctttaa
    27601 aagcatataa gggttctatt ttaatggttt gtcatgaacc tgatttctac aatgggtggg
    27661 taaccgatac ttgggatttt agtaagttaa cctaaactat tccttaattt tttacacagg
    27721 aattactaaa atcagtaaag atatagaata aatactgcta gatatgtgat ggtttaggta
    27781 actgatcacc aaccaaaaaa gatgtgacta catctttttt ttatctaatg gaatggtgta
    27841 aagtcgttta ataatagctt attttttgat gatcagttgt tcatgaaatt gttggtgatt
    27901 aacaagtcat ttaagataca aacgttatta ctaaaaagtg attcaaatag tttccctatt
    27961 tttatgtttt ttttaaattt attacgaata aatagataaa gacagtgaag atgattagta
    28021 agtacatctg ctaagattac gaatagatgg ggacaataaa tgacgaattt aacgttttat
    28081 gcaaaaatcg gtatttcaga agaagagcat gactcttttg ttaaagaaca tcagcaaatt
    28141 agcgttttac aaggtagtga ttgggcaaaa atcaaaaatc aatgggagaa tgagcgaatt
    28201 ggtatctata aagaggaaaa gcaggttacc tctttatcac ttttgattaa gctattgcca
    28261 cttggaagaa gcattattta tattccaaga gggccagtca tggattatct tgaccgtgat
    28321 ttggtggtat ttaccatgaa aacactaaag gattatggta aaactaaaaa ggccctcttt
    28381 atcaaatatg atccagctat cctgttaaaa caatacgcac tgggacagga agaagaagaa
    28441 aaacctttag ctttagcagc tattaagaat ctccaagaag ctggtgttca ttggactggt
    28501 ttaacaatgg agattgcaga tagtatccaa cctcgtttcc aagctaatat ttacactcaa
    28561 gaaaaccttg agatgcaatt tcctaagcat accagacgtt taataaaaga tgctaagcag
    28621 cgtggtgtag aaacatatcg tgccagtcaa tcagaacttc acaaattttc caagattgtc
    28681 tccttaacag aaaaacgtaa aaatatttct ttgcgtaacg aagcttactt tcaaaagttg
    28741 atgactactt atggggataa ggcctactta catctagcaa aagtgaatat tcctcaaaaa
    28801 ctagatcaat accgccagca attaaatctt attaaccaag atattactcg cactcaagct
    28861 catcaaaaga agcgtttaaa aaaattagaa gatcaaaaag cttctttaga acgttatata
    28921 actgaatttg aaggctttac agaccaatat cctgaggaag ttgttgtagc aggtatatta
    28981 tctatttctt atggaaatgt tatggaaatg ctttatgctg ggatgaatga tgattttaag
    29041 aagttttatc ctcagtatct gctgtatcct aaagtttttc aggatgctta tcaagatggt
    29101 attatttggg ctaacatggg aggagtagaa ggctcgcttg atgatggact taccaaattt
    29161 aaggccaact ttgctccgac aatagaagaa tttataggag aatttaatct ccctgtcagc
    29221 ccactttatc atattgctaa taccatgtac aaaatacgaa aacagttaaa gaataaacat
    29281 taaaagactc gccaaaatga gcgagtcttt taatgtttat tctgttattc ccattcaact
    29341 gttgcgggtg gtttacttgt gatgtcgtag acgatacggt taacgtggtc aacttcattt
    29401 acgatacgtg ttgagatttt tttcaagaca tcccaaggaa gttgagcaaa gtcagctgtc
    29461 ataccatcaa tagacgtaat agcacgaatg gcgatggtat aatcataagt acgaccatct
    29521 cccatgacgc ctacagaacg gacacctgtg ttaactgtaa agtattgcca cacgtcacga
    29581 tcaagtccag ccttagcaat ttcttcacga aggatagcgt ctgattcgcg aacggtttca
    29641 agtttttctt cagtaattgc tcccatgaca cggatagcaa gtccaggacc tggaaatggt
    29701 tggcgccaaa caatttcttc aggcattcca agagcgattc caagcgctcg aacttcatct
    29761 ttgaaaagag tgtttaaggg ctcaatcaat tcaaactgca tgtcttcggg gagaccaccc
    29821 acattgtgat gtgatttgat ggtttgagca gtttctgttc ctgactcaat gatatcagta
    29881 taaagtgttc cttgggcaag gaagtcaaca ccttttaatt tgctggcttc atcatcaaaa
    29941 acatagacaa attcattacc aataatttta cgttttttct caggatcttc aacgtctgca
    30001 agaaggtcta agaaacgttt tgaagcatcc acacggataa tatttaggcc aaatttgtcc
    30061 ccaagcattc ccataacttg atcgccctcg tctttacgaa gaagaccgtg atcaacgaaa
    30121 atacaagtta attggtcacc gatagctttt tgaagtagaa caccaacaac tgaagaatca
    30181 actccaccag aaagacctag aagaacttta cgatcgccta cagtttcacg aattttagta
    30241 atttccatgt caataaaatt atccattgac caatcaccac gcgcgccaca aattgatata
    30301 gcaaagtttt taagaatgtc attcccataa acagagtgtc tcacttctgg gtggaactga
    30361 ataccgtaaa ggtttttctc agtattttca atagctgcat agggacagtc atttgagtct
    30421 ccaacaaggt ggaaaccttc tggaatttca gtaacagcat caccatggct catcaaaacg
    30481 agttgttctt gaggtgtgcc tgaaaataat tttgacgttt cacgaagatg aagggttgac
    30541 tgaccgtatt cacgattacc agcttgtcca gcaggaacaa ctttaccacc taatttatgg
    30601 gtgattaatt gcataccgta acagatacca agaatcggaa tccctagttc aaagatttca
    30661 gggtcaatgc caaaggcgtt atcagcgtaa acagagttag gccctcctga taaaacgata
    30721 cctatgggat tgatctcatg aagttcttga gcggtgattt tatggctttt tagttcggag
    30781 aaaacaccaa actctcgaat acgtctagca ataagctgat tgtactggct accataatca
    30841 agaacgataa ttttttgaac atcattcaaa attgaaattt cagtcattat aatcctttca
    30901 ttctatacca accgtcaggc tgatagttgt caacttattg tagcatattt tcatcgaaaa
    30961 gacattacaa tttctctagc tcgttggaaa aaaacgtaat cgttatgtta caatagaggc
    31021 tatgaaaggg aattaagaca acagggaggg cctatgctaa gaaaaaagag aattttgggt
    31081 ttatttcgac ctgttgaatt aattttccta ggattattgt tgagtttagt tgtttcgtac
    31141 cttgcgtgga ccaatagttt tgcaacactt cataatatat tagcaactgt cggaatagtg
    31201 gaacgaagca aagatcaaca gcctcgctat cacattggac aagctattca agtacaaaaa
    31261 agtggtccat atcatcaatg gattggaact attaataaac aggtagaaga tatagccgaa
    31321 aattaccgag tgagttatca ttatgaagtg gtatttccaa taggaaaagt cactgtttct
    31381 ttgccagaac ataacctgaa aaagcctgat aaaccgaggt ttaaaaaagg agatatcgtt
    31441 aaattatctt cattaactaa aaagccacat ataaaagtgt atcaaggtca attagcgact
    31501 attaaacaag ttaaaaaacg ctatgactat tcgttaggag gatatcagta cgatattaac
    31561 ctgaaagata atctaagatt agatggaatt tcagagcaag attttgttaa accttattat
    31621 attaggttca ataaaggaaa ttcccctgag caaaacaatc gtcttttgcg aaaagctttc
    31681 gcctatgcaa agcagcatcc aaatagcgtt atatcttttc caaaggggca atttcacatt
    31741 ggctctttgc cttcacaaaa agattatttt gagcttccat ctgatacagc tattattggt
    31801 catcagacag agttcattat tcacggtaaa atgttgtggt ttggattccc tacaggacca
    31861 aaggctgaac aaggtgttcg taatctcgtg ttgactggag tgcatttcaa agcaaatgat
    31921 ttgaaaaaag gagaccactt tatgattatg gctgatcatg gtactgattg gcatatttac
    31981 gataacaaat ttactatggt tcataagcgt aatagtcata tttttgattt aggatctcta
    32041 caaaattcat tgtttgagaa aaaccaattt attggctatg cgccagaatt agtacaagac
    32101 caacagctgc tatcaaaggc tcaagggcat gatttttttt cagaagtcat tcagtttgat
    32161 gctgctgttc atcattttgc atgggatgga ggtctactta gtaatattgc tccaaactat
    32221 gaagcattta accaaactcg acatctatgt cacaatatta ctgtaagcca aaatcaattt
    32281 ttaccttata tagatccgac tggttgcctg agagcctata gtggttctat tggtcagcat
    32341 tcctcaaagg taggagttat tagggtttta aataatgttt ttacctcatc cattgttact
    32401 aaagcgaagc tcactagttg gtttatggaa cctattcatt ttccaccaaa ttcaccggtt
    32461 attgtcgcag gtaatatcat taattgatgc caaatacctc aatatttaca attcaatttt
    32521 catcaaaaat atgataaaat agatgaataa ccgacttgag gagtgtggca tgttaccagc
    32581 ttatataaaa attcatgatg caattaaaaa agacattgat ctgggcatct ggccaattgg
    32641 tagtcgctta ccaagtgaac gacatttagc ggaacatttc accgttagtc gaatgactct
    32701 acggcaggct attaccttac tagtagaaga agggattctt gaaaggcgga taggaagtgg
    32761 tacttatgtt gccagtcatc gtgttcaaga aaaaatgcga ggaacaacaa gtttcacaga
    32821 aattatacgc tcccaaggac gacaaccctc ctctaaatta ttatcctatc aaaagcaatt
    32881 agctagtgat actgaagtta aagaattgaa cttagacaaa acagacttgg tcattcgaat
    32941 ggaacgtatc cgctatgcag acagtgtccc tttggtgtac gaaattgctt caatcccaga
    33001 aaaatttata aaaacggtta aacgagctga tattacagaa cacttttttc actcattgat
    33061 agcaaatggt tacgagattg gtaaaagtaa acagacaatc tacgctaagc tagcaagtga
    33121 gcgtgtagcc tcctacttgg aagttgctaa aggacatgcc attttggctc taactcaggt
    33181 gtcttacttt acagacggca aaccttttga gtatgtccgc agtcagtata tcggtgaccg
    33241 ttttgaattt tacttagaaa ataattagta aagaagtcat ttatgacttc cttttttaca
    33301 cgaacagcat aaggcaatta atttgctact gttaaaaaca atcatagtat gataaaatga
    33361 acattatgga aattgaaaaa acaaacagga tgaatgccct ttttgaattt tatgcagctt
    33421 tgctaacaga taaacaaatg aattatattg agctgtatta tgccgatgat tatagcttag
    33481 ctgagattgc tgatgaattt ggtgtcagtc gtcaggctgt ctatgataat attaagcgta
    33541 cggaaaaaat tttagagact tatgagatga aacttcatat gtattcggat tatgttgttc
    33601 gaagtgaaat ctttgacgac atgattgctc actaccctca tgatgagtat ttgcaagaaa
    33661 aaatttccat tctaaccagt attgacaata gagagtaaga ggagttttga ctatggcttt
    33721 tgaaagctta acccaacgtt tgcaagatgt gtttaaacac attcgcggta aaaagaaatt
    33781 atcagaatca gatgttcaag aagtgacaaa agagattcgt ctagctcttt tagaagccga
    33841 tgtcgcttta ccagttgtta aaacctttat taagcgcgta cgtgagcgcg ctattggcca
    33901 tgagattatt gatactcttg atccaacaca acaaattctt aagattgtta atgcagaatt
    33961 aacgagtatt ttaggctcag aaaccgcgga gattgataaa tctccaaaaa ttccaactat
    34021 tatcatgatg gtcggtttgc aaggggctgg taaaaccact tttgcaggaa aactcgctaa
    34081 taaattaatt aaagaagaaa acgcgcgacc actgatgatt gctgccgata tttaccgtcc
    34141 agcggccatt gatcagttaa aaacactggg gcaacaaatc aatgtacctg tttttgatat
    34201 ggggacagac cactcagcag tcgatattgt cagaaaaggt ttggaacaag ctcgtgaaaa
    34261 ccgcaatgac tatgtcttga ttgatactgc gggtcgcttg caaattgatg aaaaactgat
    34321 ggaagagctg cgcgatgtca aggctttagc acaaccaaat gaaattcttt tggttgtaga
    34381 tagcatgatt ggtcaagaag ctgccaatgt agcctacgag tttaatcatc agttgagcat
    34441 cacaggggtt gtgttaacaa agattgatgg tgatacccgt ggaggtgcag cactatctgt
    34501 ccgtgaaatc actggaaaac caattaaatt tacaggtatt ggtgaaaaaa tcacagatat
    34561 tgaaacattt cacccagacc gcatgtccag tcggattttg ggaatgggtg acttactcac
    34621 tcttattgaa aaagctagcc aggaatatga tgagaaaaaa tccttagagt tagctgaaaa
    34681 aatgcgtgag aacacctttg atttcaatga tttcattgaa cagttagatc aagtgcaaaa
    34741 tatggggcct atggaagacc tcttgaaaat gattccagga atggctggta acccagcttt
    34801 ggccaatatc aaagttgacg aaaaccaaat tgctcgcaaa cgtgctattg tctcttcgat
    34861 gacccccgct gaacgtgaaa accctgactt actaaacccg agtcgtcgcc gtcgtattgc
    34921 agctggttcc gggaacagct ttgtggaagt taataaattt atcaaagact ttaaccaagc
    34981 caaaagcatg atgcaagggg ttatgtcggg cgatatgtct aagatgatga aagatatggg
    35041 cattaatccc aataatcttc ctaaaaacat gcctgctggt atgccagata tgtcttcctt
    35101 agaagggatg atgggacaag gtggtatgcc cgatttatct ggccttggtg gtgatatgga
    35161 tatgagtcaa ctatttggta aagggttcaa ggggaaaatt ggacaatttg ccatgaaaca
    35221 ggccatgaaa cgtcaagcta acaaactaaa aaaagcaaag aaaaaacgaa aataaaagag
    35281 acggaaattt tcgtctcttt ttgatgtgaa attcatttat cttgtataca agattattaa
    35341 aattatggaa gaccgcgtta catgcatgat gagttcattt aaaatttgaa ataacctaat
    35401 caatctaact taaatttcta agggcctaaa attagcgata attttgccaa taatgcgagg
    35461 ttcttcgcta tagggagcaa acttatcaga atatttttta tttaaggaca ctagacgtaa
    35521 tccctcatct tcacgaaata cctttttgat atatgtttgc ccatcccatt cgactgcata
    35581 aattgctcca tcgtaatcaa aactattttg ttttataaga acaacttcgc catttaaata
    35641 agttggctcc atagaatctc caaaaaccca agacgcaaaa tcgtattcta attgttcatc
    35701 gtaaaagaca acatcaaagt taccatcacc aaaataggag taaccagtac cagcagataa
    35761 actttcatag acccgataag catataattg tgatggttta tctatgagat ctttagattt
    35821 tttgtctatt tgatgattta acaatcgctc tgaatagcca attacttttt ctttattaga
    35881 tattgtcagc tggttataag gcgttagcaa tctatagttt gggtcgaaat aatcagatgt
    35941 cacattgaat agatgcaata aggcatttaa atgtttttca tttggtatat tcttaccttt
    36001 ttcccaatta gatattgtca ttttattgac atgcaacaat cttcccaatt ctgattgagt
    36061 tattcccttt gataatcgtg ctgtttttag ttgatgtcca gaaaacattt ggtagctcct
    36121 ttagtaaagt tataacttta ctaatagtat caaaaaaata aaacgaaagc aagtgtaaca
    36181 tttcctacaa ttaattcatg tgatagcaat actgtcaaaa aggggaaaca cctaaaacat
    36241 agcgactaga ttcgtgtact agcaggtcta tatctaataa agagttaatt actttaaaga
    36301 taaaattatc atttagttct gagctaaaca aattctgtgc ctgaagttac taaaataatg
    36361 atagtaaatt attactgaat ctaaaagaag tgacgttagt atctgtaaaa aaagagattt
    36421 gtctcgtgac atctttccga aaaactgtaa ttttcttgaa aaatatttat aggtgtgata
    36481 tactgctctt gtagagaatg aatgacataa aatacatgag acaatttgcg aaaattcatt
    36541 tttgaaaaaa ttgttattgt taaggaatta tgatgatatg agacgcgaat tattactaga
    36601 aaaaattgaa acctataagg ccatcatgcc ttggtatgtt ttagattatt accaatccaa
    36661 gttagctgtt ccatacagct ttaccacctt atatgagtat ttaaaagaat acaaacgctt
    36721 ttttgattgg ctgatggatg ctgatttaac gcaggcgcca aagattgctg atattgactt
    36781 gagcacgctt gagcacctta ccaagaagga tttagaggcc tttgtgcttt atttgcggga
    36841 acgaccttct ctcaacacct attccaccaa agaggggctt tctcaaacca ctattaatcg
    36901 gaccttgtct gccctatcaa gcctttacaa gtacttgact gaagaggttg aaaatgacca
    36961 aggggagcct tatttttatc ggaatgttat gaaaaaagtg tcaacaaaaa agaaaaaaga
    37021 aaccctggct tccagagcgg aaaatattaa gcagaaactg tttttaggtg atgaaactct
    37081 agctttcttg gattatgtgg ataaggaata tgagcaaaaa ttgtctaatc gtgccaaatc
    37141 ttctttccgt aaaaataagg agagggattt ggctattatt gctctactac ttgcttctgg
    37201 tgttcgtttg tctgaagcag tgaatcttga tttaaaagat gtcaatctaa atatgatgat
    37261 tatcgaagtt attcgcaaag gcggaaaacg tgattcagtc aatgtagcag gttttgcgaa
    37321 aggttatttg gagtcttatt tagctgttcg tcagagacgt tacaaggctg aaaaacagga
    37381 tcttgctttc tttttaacag aataccgtgg cgttccaaat cgaatggatg cttctagtat
    37441 agaaaagatg gttggcaagt actctgagga ttttaaaatt cgtgtgactc ctcacaaatt
    37501 gcgtcatacg ctagcgacaa gactatatga tgctactaaa tctcaggtgt tagttagtca
    37561 tcaattaggc cattcctcta ctcaagtcac ggatctttat acccatattg tcaatgatga
    37621 gcaaaaaaat gctttagata acctttaatg ttgcataatt gtttttatgt aacattaaag
    37681 gtaaaaatag cttcaaaatt aagtttaata gatggctact attaaccgtg acagtttggt
    37741 gtcaggccgt tttccaaact actcaagcca cttagaaaaa ggaatatcac tgctaacttt
    37801 gtcccttctt tgaatgactt ttttgtgatg tttatagatt aaatctagta gggttctcat
    37861 caaaaagatg agataagccc atttttagta tgtcagtact tttatttagt atgataatac
    37921 gttattttgt aaagtagctt ttaggattat tcttattaaa ctacttaatg tcattactga
    37981 taacttagag taatataaag ctaaaactga aggaatgtta gagaatcatg aagacagctt
    38041 ctttaacatc aattggttga aaacaagaat cagataacat tatcgttaga tagactgaag
    38101 aatcaaaaac acagtttgtt acataaataa attcttgtca aaacttgtat tttctatttg
    38161 aactgatacg attgacaaag gctaaactaa aatagcttga cttttttaga atctttgtgt
    38221 ttttttgtcg gatcccctcc tattttttcc ttgaattgat ctatttaacc ttttagaaca
    38281 aggtttatcg catactattt ttagacattt tgttataata aaaagaaacg acttgaggag
    38341 ataaaagatg ccaaagagaa taagaaaagc tctaggagta gttgggaaac tgatgtcaat
    38401 tgttcctgac actactgaaa ttattggaaa aacgattgat aacagtcgac caattatcga
    38461 aaaacgtatg gaacaaaaac atgaaaaaga gatgcaacta cgcacgatag atgatgtgat
    38521 taatcttcct gttgatcagg cacaagctca tttggaacaa cttggctttg tagtagccac
    38581 tatacctgct aagcctcata aaaaatggct tcatagtaat ctcaatgaag tggttgctat
    38641 gtctccaaaa tctggtaaat ataagatagg aagcctgatc aaactctact acattactgt
    38701 tgatgttttg gaaaaaagtc aagacttatt agaccaagaa aacttgcgga ctgtggaacg
    38761 caatcaaaaa atcgctgata cttttgagtc tgtcaaacac attcgatttc cttttaaaaa
    38821 atggcgttga taaaaaacag agttgccttt agatagatca gcctgttttg gtactaagtt
    38881 acattatgat tcaataaaat taaagataag gagaagaaat gccttactac actatttcaa
    38941 aagtctttcc ttcagataaa acgacaatgg ctagtgtaaa gaacctgctt catcaagaag
    39001 gtattcgttt ggatgctcat ttagattata cttgtgccat catgaatgcg caaaatgatg
    39061 tgattgctac cggttcttac tttggaaata gcttgcgctg tctttgcgta tccagtgcct
    39121 atcaaggtga aggacttctt aataggattg tgagtcatct cattgatgaa gaatatgccc
    39181 ttggcaacta tcatcttttt gtttatacga agacctcttc tgctgctttt ttcaaagatc
    39241 ttggttttac tgaaattgtc catatcgaca atcacatcag tttcttggaa aataaaaaaa
    39301 ctggttttca agattatttg atgacactta ataagcctga gcaaacacct ggtaaagtcg
    39361 ctgctattgt tatcaacgct aaccccttta ccttagggca tcaattttta gtagagaaag
    39421 ctgcaagaga aaatgattgg gttcatctgt ttatggtcag tgaagaccgc agtctaattc
    39481 ctttttcggt gagaaagagg ttgattcaag aaggtctagc tcatcttgat aatgtcatat
    39541 atcatgaaac aggtccttat ttgattagcc aagcgacttt cccagcctat ttccaaaaag
    39601 aagacaatga cgtgattaag agccaagctt tgctggatac cgctattttt ctaaagatta
    39661 ctcaaacctt acagattaca aaaagatacg ttggagaaga gccaaccagc cgagtaactg
    39721 ctatttacaa tgaaattatg gcagagcagt tgcagcaagc tggtatcctc ctagatattt
    39781 tgccaaggaa agctatcaat cagcagcaag atcctatcag tgcctcaacg gctaggcagg
    39841 cattgaaaga taatgattgg gaccttctgg caaaactcct tcccaaaacg tctttagatt
    39901 atttttgttc gctagaagcc caacccatta ttaaaaagat acaagccact tcatctgtca
    39961 aacattacta agataaaaaa cctatctgat tatcaaaatc aggtaggttt ttggtattgt
    40021 tcttacagca aatgcgtttc accaaggaga ttaatggtta agaggattag tcattccctg
    40081 ttagtcttga atgtccagtt gtacagtaac ttcttgaacc ggaacatcat agaaaggatc
    40141 ttcacggcgt cccaagaaat ctctggcttg ctgtgggaaa ctcgcatagc ttaacacgtc
    40201 ttcttctgaa cgagcgtatt gagcaatctc gtcatgtaga taaatcattt gaggctcgat
    40261 taggtcggct ggtctgcaag taataactgc ttcgtcacca atgattttct ctttgatacc
    40321 ttctgctaat ggggctggtg attgaccgta tagccctcga acatagtctt tgatttcatt
    40381 tggaactacc ttgtagcgtt cccctgagat gatattcatc aaggcctgtg tgccaaccat
    40441 ttgtgataat ggcgttacaa gtggtggata tccaagatcg gcccttactt taggtacttc
    40501 tgctaagact tcttcgtatt tatcagctag gccttgctcg gttaattggc tcaataggtt
    40561 tgatagcatg ccacctggaa cttggtaaat caatgttttt ggctcagtat ctttgacttt
    40621 aggatttaaa atccctattt ctcgatagtg gtcacgaata gtgttgaaat attctgcaac
    40681 tttggccacc tcttgcatat ccaagcctgt gtcaaagcct aaatccgtca aggcaatcgc
    40741 cattgactct gtggcaggct gactggttcc ccctgaaaaa gaggaaatcg ccgtatcaat
    40801 aatatcagct cctgcttctg ctacttttaa gtaagtcatt tctgaaatac cactggtagc
    40861 atgggtatga acctcaagag ggatagttgt attctccttg atacatttga ccaattggta
    40921 acctatttca ggagttaaga caccagccat gtctttgata caaatggagt cagctccgat
    40981 agcttggtaa gctttcgcca attcaacaaa gtagtcaatg gtatgtaccg gacttatcgt
    41041 gtaagaaatg gcaacttgag catgccctcc aaatttttta gtcgctgaaa cagctgtttg
    41101 caagttgcga gggtcattta aagcatcgaa gatacggaca atatcaatcc cgttttcaat
    41161 ggatttttga acgaaggatc tgaccacatc gtcagcataa ttgcgatatc caagaaggtt
    41221 ttgtccgcgt aagagcatct gaagtttagt ctttttcact gctttatgga tggctcttag
    41281 ccgttcccaa gggtcttcat ttaaaaagcg taggcaggaa tcaaaggttg ctcctcccca
    41341 catttcaagg gcatgataac cagcattgtc tagcgtttcg agaataggaa tcatttcctt
    41401 ggttgtcata cgtgtggcaa tctgactttg ttgaccatca cgtaaaactg tttccgttat
    41461 acggattttc gtcataattg ttctcctcat caacctgtct tatctgatga cgatgattgg
    41521 ttgtctttat tgaaaaatga atagagtaat tttgaaatag cagtctgcat ctcctcgaca
    41581 ctgtgcttac gtaggcgacc gcagactttg gcctctttag aacagataaa acattgccta
    41641 ggggagcctc ctaatacggt tctgctaatt gaatgaggca gatcattttg caagaccaag
    41701 acatctaaat ccatgagacg acctattggc aactctgtct ctaaggctat catttttaac
    41761 ttcaggtagc ggctaggtag acttgtgatg aggtaatact cataacccgt tgtaggcagt
    41821 aatcgcaact ggtaacaaat cttatcgtca gctaaggcag tttgaatggc cttaatcact
    41881 atatcaaaaa cttcaagaag tttaggagag gttttaattg gtccagggat attcatggtg
    41941 accgataata agctaccttc tgggtactcc tttaataaat gcagctgacg cagagctctt
    42001 tcttcgcggg ctcttaacat atcactaagt tggatagctt cgcctgaaaa ataagtgtct
    42061 ttacacattg taaaccacat ccatgaggct accatcacgg tattcaataa gagcaacaac
    42121 cttatcacca tattgaatac gctcaggtgt gccaacgata gcgtaagcct tctcttttag
    42181 ctcctcaata ctaaattgtg gcacattgag ggatttgaaa tggtctacta agtcttgacg
    42241 atttgggtta atggcaattc ccacttctgt gacgaccaca tcgacacttg ttcctggtgt
    42301 aatgaccgta ttaacctcat ctacaaaagt tgggatgcgt ccgcggataa gtggtgaaat
    42361 aaccaaactc atcttagccg caaaggcagt gtcgcagtgt cctccagaag cgccacgaat
    42421 cacgccgtca gatcctgtca tcacattaac attgaagtta gtatcgactt caagggctga
    42481 taaaatacaa gtgtctaatt gattgataac agcacccttg ctcaaaggtg aggcatacat
    42541 gttggcatca atttcataat ggtcagcatg cttaccaaga gaaacagctg atgggtgatc
    42601 aaagtcttgg acatcaagaa ttttttcaac cagtccttct tcgagcaact ccaccatagc
    42661 attggtaata ccaccaagag caaagctagc tttgatattt tctttaatca tagcttcacg
    42721 catgaaacgg gttactgcca aagaagcgcc acctgttcca gtttggaaag agaatccttc
    42781 tttaaaataa ggagagttgg tgattacttt agcggcgtat tctgcaatta agagttcttt
    42841 aggatttttc gtaaaacgag ttgccccttt ggcgattcct tgaggatctc cgatagcatc
    42901 cactgttacc acatagtcaa catctgtttg aggaatgctg attggggtat taggataagg
    42961 aaccaaatta tctgtcaaga taaccacctg atccgcatat ttggcatcaa tcatggcata
    43021 gcccaaagaa ccacaggttg ctttcccttt tgtcccatta acatttccgt aagcatctga
    43081 acttggggcg cccagaaagg caacatcaat atggatatcc ccactagcaa tggcacgagc
    43141 gcgaccacca tgggagcgaa taaccacagg attttccatt agtccttctg agatggctgc
    43201 ccctactttg tcacgaagac cagatgaagt gatgttagtg accacaccat ttttgatgtg
    43261 atcaatcaaa ggctcatgta cattagcgat ggaacttggg gcaatagaca ggtttttaat
    43321 gcccattttg gcaatttcct ccaagaccat attcataatg aaatcccctt cacggaaatg
    43381 gtggtggaaa gaaatggtca tgccatctgt taaacctgtt ttttcaatcg cttcacgaac
    43441 agatcctagt aatttagaat ctccaggctt aactggttta atacggcgac ttgattcgtc
    43501 atactgtttg atatttgcga gttctccttc aaagacaccg tattggtcgg cgtatggttg
    43561 aggaatatct ctaccgagtt tatttgttac catctttaaa tgtcctcctc agataaaaca
    43621 cctgctgctg ttgctagggc aatgacacgt tctgcacgtt caacgattgg tttatcaacc
    43681 atttttccat ttaaggaaat aacgccagag cctttgcttt cagcttcacg aattgcccag
    43741 atgacttgtt tggcatggtc aatttctttt tttgttgggg tataaatctc attgaccaga
    43801 ggaatttggc gagggttgat gaccgattta ccatcaaatc ctaactgttt gatcatgcga
    43861 acttcgtttt ggaacccttc ggtattattg acatcagaat aaacagtatc aatggcagca
    43921 attccagcag cacgagcagc gtgtaaaatc atgctacgag caaagaataa ttcttgacca
    43981 tctgggtaac gacgcgtttt catattcgtg acatagtctt ctgctccaag agcaatacca
    44041 atcaagcgct tagaagcttt ggcaatatca cgagcattta ggacaccttc ggctgattca
    44101 atggctgcca tcatgcgtgt gcgaccaact tcaatgccgt tttcgcgttc gacacgttca
    44161 ataacagcct ccacatcaat aatatcttga gcagtctctg tttttggaag acgaatcacg
    44221 ttgacacctg ccaaaacaac agcttcgatg tctaaagccc cacaagaatc aagaccattc
    44281 acacgaacaa ccgtttcaac gcttgaataa tcaaaagttt taagcgcaaa atggacgaga
    44341 gctctagagg tgtctttttc tttgagtgaa acagaatctt ccaagtcaaa catgacggaa
    44401 tcagcgccaa ataaaggagc atctcgaagc atggctgcat tggcaccagg cacaaacatc
    44461 attgttcttc ttaaacgttc catgagtcaa tctccttcca atcatattgg tcaataccag
    44521 cagcgcgatg aacagctgcg atggttctcg cttgaatggt gcaatctaat gcacctttat
    44581 caacagcctc tactttagca gccgtcacct tcaaattcac tagggtttga tgaatgagtt
    44641 gacgaatgtg attgccaaat tgtttttcaa cactactgtc tagggttatt gtaatagttt
    44701 tctcgtcatt aggggatact gtaatcatta ggtcacttga ttcaagtgaa ccagcaacgg
    44761 cagtttgttt aatatccatt gcgtttacct ccttgatttt cttaaatgat attgttattt
    44821 actaactggg aaaagtttga tcaggatctc tgcgacaaga tagagaatgc ctaacacgat
    44881 aaagacacct gccataccaa gcgccattag ctcaaaggaa ctaatcaaat ggtccatatt
    44941 aattgtcata aggtttcctt cctttcttag ctaaagtaag ctagcaacaa accacctgcg
    45001 ataacagagg cgatttggcc agagacattg gcacctacag catacatgag gataaagttt
    45061 tgcgggtctt catctgttgc cattttttga atgacacgac ttgacattgg aaaagctgaa
    45121 atacccgcag cgccaatcat tggattaatc ttctcttttc ggaagagatt gagaaatttg
    45181 gcaaacatga ccccaccgat agaatccatg ataaaagcaa gtaaaccaaa gacgatgatt
    45241 aagagtgtct gtacatttaa gaacaggtct gcctgcattt taatagagat ggtcaatcca
    45301 agcaagatac taataatgtt taccaattca ttttgagcag tttgtgacag gcgatcgagc
    45361 acaccacact cacgtaataa gttaccgaac atcaaaaagc caactaaagg tagagaaatt
    45421 ggggcgatga accctgctac taaggtaatg atgattggga ataagatttt agtcatttga
    45481 gatacattct cagctttgta agtcgtacgg atacggcgct cttttttcgt tgtcactaat
    45541 ttaatggcaa atggttggat aataggaacc agagccatgt aagaataggc tgcaaccgta
    45601 attggaccca gtaaatcctt ggccagttgg ttggcaacaa agatagaagt cggtccgtct
    45661 gctgctccga taatgccgat tgaagctgct tctttaatgt caaagccaac cagtacggca
    45721 acaacgacaa caaagaaaat tccgaattga gctgcagcac caaacaagag catgaatggg
    45781 ttttgaagca agggaccaaa gtcaatcatg gctcctatac caatgaaaat caacagtggg
    45841 aaaagttctg ttccaatccc aaaattgaag agagcctcaa aaaccccttc ttgctcgact
    45901 ccgttaacca cttgggttaa aactcctgaa ccagggaagt taacgagaat ggttccaagt
    45961 cccatgggga caagtaaggt tggttcgtat tcttttttaa ttcctagata cattaagagg
    46021 gcaccgatga ccatcataac aatttgagga atggtgatgg aggttattcc tgcgattaaa
    46081 gtgtccacaa attcacttcc ttttctgtct atttattcta gttatagtac tattaaccaa
    46141 ttgtaatgag accatcacca ggattgacca cttgacctgg accgacgtgg atagctgtaa
    46201 tggttcctgc tgataaggcc acaatctcat tttccatctt catggcttct aaaatcaata
    46261 gtggctgatt ttcagttact tggtctccca ctgctactaa gacttttaag atggttccag
    46321 gcattggtga tggaatggca tccgctcccg ctgcagctac tggctgtggt gcttgcgctt
    46381 cctccacttg tgggcttgct tcagtaggga caggtactgg agtggatatt ggttgagcgg
    46441 gggcagctgc ttgggcagga gcaccgattt cttccatttc tacaagatat tctttaccgt
    46501 caatggtaat tttaaatttt cgtaacatca tttttctcct atatgttatt gtgtcatgag
    46561 ttcatctaaa gtatcgttca ccgactacct tttgcaatag atggatgtca cccgaaactg
    46621 actttctggg taaacacctg cagcgatact tgaagcaatt aaagaaacag tgattgcctc
    46681 aggattgcgc ttgagaatgc gtttaacctt gaattgacta ttaggtctat cgccagcagc
    46741 aataacactg gtaattaaag taaccttttt gtaatcactt ttgtctgcag gaatataagc
    46801 gggaatcttt tcccagtttt cagaaggttc tatttctgta ctaaggggcg aggattcttt
    46861 caacttctct tttttagagt gtttaaacca tttttgtaaa aactgcatga gctacctctt
    46921 tttcacattt acctatttag ggaactagta agtttattat atactaccaa tcttttttga
    46981 gatggctttt ttgtgttctt tctaagagcg ctttcaatgt ttcataaagc ttttcaacag
    47041 ttacctttta ttttgttttt aggtaactgt tgaaaaactg agatcaagat actgatagca
    47101 agaaaagct
//
LOCUS       DATTYN010000014        44111 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.14, whole genome shotgun sequence.
ACCESSION   DATTYN010000014 DATTYN010000000
VERSION     DATTYN010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44111
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.14"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(<1..194)
                     /locus_tag="VB649_000959"
     CDS             complement(<1..194)
                     /locus_tag="VB649_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin domain-containing protein"
                     /protein_id="HEP1669918.1"
                     /translation="MPNLYDFTVKAQNGNDLSLAAYKKKVVLIVNTATKCGLTPQYQA
                     LQALYDTYHDKGFEVLDFPC"
     gene            complement(187..1986)
                     /gene="pepF"
                     /locus_tag="VB649_000960"
     CDS             complement(187..1986)
                     /gene="pepF"
                     /locus_tag="VB649_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEP1669919.1"
                     /translation="MELKKRSEFPENELWDLTALYKDRQDFLLAIEKALQDIDLFKRN
                     YEGRLTSVDDFTQALIEIEHIYIQMSHIGTYAFMPQTTDFSDESFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLDVLDTLEKNPYFSAAIRMAKIQKEHLLSPDVEKALANLREV
                     INAPYDIYTKMRAGDFDMDDFEVDGKTYKNSFVSYENFYQNHENAEIREKAFRSFSKG
                     LRKHQNTAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSLFDRQIDLIMTEFG
                     PVAQKFLKHVAQVNGLEKMTFADWKLDIDNELNPEVSIDGAYDLVMKSLAPLGQEYTK
                     EIERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEHQFDDPRQKRFSLAHRLTDTYF
                     HNFITHLLEATFQRKVYTLIEEGGTFGADQLNAMMKEVLTDFWGDAVDIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPDGAEEWLDFLKSGGSRTPLDTAMLIG
                     ADIATEKPLRDTIQFLSETVDQIISYTEEMSHA"
     gene            2145..4943
                     /gene="ppc"
                     /locus_tag="VB649_000961"
     CDS             2145..4943
                     /gene="ppc"
                     /locus_tag="VB649_000961"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEP1669920.1"
                     /translation="MIEETSKEGDGHLPLKKLESSNNQDIIAEEVALLKEMLENITRR
                     MIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVD
                     LAYEINYQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTIL
                     ELTTHIHKLLRKYRDAKAGVINLEKWRQELYRYIEMIMQTDIIREKKLQVKNEIKNVM
                     QYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCL
                     SATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRR
                     AFHYIQSRLKQTQIQLTNQPAARMSSSVGLNTSAWPSPASLENPILAYDSPVDFKADL
                     KAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGAN
                     IVDDYSSLSETEKCDVLLQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGE
                     EVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNARDIMAA
                     YLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKI
                     TFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEM
                     LISASINRMVTQMITDPNEIDSFREIMDSIVADSNTIYRKLVFDNPHFYDYFFEASPI
                     KEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQ
                     GNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEW
                     QLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDE
                     KLIHTTINGIATGLRNSG"
     gene            5083..6387
                     /locus_tag="VB649_000962"
     CDS             5083..6387
                     /locus_tag="VB649_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEP1669921.1"
                     /translation="MIISRSRGKTMKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSV
                     SLIQAHANPFKSVINQGVFWIISLVAITFIYKLKLNFLTNTRVLTVVMLGEAFLLIIA
                     RFFTTAIKGAHGWIVIGPVSFQPAEYLKIIMVWYLALTFAKIQKNISLYDYQALTRRK
                     WWPTQWNDLRDWRVYSLLMVLLVAAQPDLGNASIIVLTAIIMFSISGIGYRWFSAILV
                     MITGLSTVFLGTIAVIGVERVAKIPVFGYVAKRFSAFFNPFHDLPDSGHQLANSYYAM
                     SNGGWFGQGLGNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGFILALVFFLILRIMNV
                     GIKAKNPFNAMMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVA
                     VGFVLNIDASEKRDDIFKEAELSYRKDTRKENSKVVNIKQFQ"
     gene            6741..7937
                     /gene="tuf"
                     /locus_tag="VB649_000963"
     CDS             6741..7937
                     /gene="tuf"
                     /locus_tag="VB649_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEP1669922.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDTKFEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIKEETKKAVVTGVEMFRKQLDEGLAG
                     DNVGILLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILSKDEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTINVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
     gene            8178..8936
                     /locus_tag="VB649_000964"
     CDS             8178..8936
                     /locus_tag="VB649_000964"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEP1669923.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVEAVASKLPSTDLVDVAVAAP
                     AVDLVTTVEAAKDSVLKVAAQNCYFENTGAFTGETSPKVLAEMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIVCCGESLETYEAGKAVEFVGAQVSAALAGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVKDYMACPDVDGALVGGASLEADSFLALLDFLN"
     gene            complement(9035..10270)
                     /locus_tag="VB649_000965"
     CDS             complement(9035..10270)
                     /locus_tag="VB649_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEP1669924.1"
                     /translation="MALIEISQEQFDYYCHSLVHHSFIQTSEMASLMAKRGAKPQFLG
                     LEKDGELKVAAMVFSQKVAGGWRMELNAGPNTNHPEELEHFYTQLKDYAKQKDVIELI
                     LKPYDNYQSFDTDGIPISHPNTDLISLLTALGYKHDGLKTGYPEGEPVWHYVKKLEGI
                     DSSRLTHSFSKKGKALIKKANTFGIKLRQLKRDELHHFKEITEATSDRRDYLDKSLSY
                     YQDFYDSFGDSCEFMVATLNFEDYLNNLKQRQLQLATSINKVKGDLGKNPHSEKKQNR
                     LKELSSQFETFQVRISEALHFLEEYGTKDVFLAGSLFIYTEQEAVYLFSGSYPKFNKF
                     YSPALLQEHAMLKAIHKGIKQYNFLGITGKFDGSDGVLRFKQNFNGFILQKPGTFRCY
                     PFPIKYHFIRLAKKLLNRY"
     gene            complement(10257..11483)
                     /locus_tag="VB649_000966"
     CDS             complement(10257..11483)
                     /locus_tag="VB649_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEP1669925.1"
                     /translation="MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERIS
                     FYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTVGKSKRAL
                     FVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
                     YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKS
                     YYQKLLDIYAGQSYITMASLDLPEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKT
                     IARLQKDLTILSEQLAAGKTRIPLAATLTLIYGETSENLYAGMDDDYRNYQAPLLTWY
                     ETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFAGEFNIPVGLVSSLAIL
                     TYNLRKKLRSTTNGTN"
     gene            complement(11483..12292)
                     /gene="yidA"
                     /locus_tag="VB649_000967"
     CDS             complement(11483..12292)
                     /gene="yidA"
                     /locus_tag="VB649_000967"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEP1669926.1"
                     /translation="MSIKLVAVDIDGTLLTDDRRITDDVFQAVQEAKAQGVHVVIATG
                     RPIAGVISLLEQLELNHKGNHVITFNGGLVQDAETGEEIVKELMTYDDYLETEFLSRK
                     LGVHMHAITKEGIYTANRNIGKYTVHESTLVNMPIFYRTPEEMTNKEIIKMMMIDEPD
                     LLDAAIKQIPQHFFDKYTIVKSTPFYLEFMPKTVSKGNAIKHLAKKLGLDMSQTMAIG
                     DAENDRAMLEVVANPVVMENGVPELKKIAKYITKSNNDSGVAHAIRKWVLN"
     gene            complement(12748..14049)
                     /locus_tag="VB649_000968"
     CDS             complement(12748..14049)
                     /locus_tag="VB649_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEP1669927.1"
                     /translation="MNEKVFRDPVHNYIHIDNPLIYDLINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTAIFEEKYADIWNKDENLVTMTAALLHDIGHGAYS
                     HTFEALFHTDHEAFTQEIITNPETEINAILVRHAPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVEDGIVFEHSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAQHLYPEQQAYFQKTAPGLIPFFEKKANLAD
                     YIALDDGVMNTYFQVWMASEDHILSDLASRFINRKILKSVTFDQDSQGELERLRQLVE
                     SVGFDPDYYTGIHINFDLPYDIYRPELENPRTQIEMIQKDGSLAELSQLSPIVKALTG
                     TTYGDRRFYFPKEMLELDDLFAPSKETFMSYISNGHFHFSQ"
     gene            14131..14517
                     /locus_tag="VB649_000969"
     CDS             14131..14517
                     /locus_tag="VB649_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEP1669928.1"
                     /translation="MKLQLTNHIRFGDETEIIQEIHDCEWREKGGYQYLIYQNTDKEK
                     VVIKYNETELTMSRFSNPQSIMKFFAGKKVLIALPTPMGVQQFLTDTSHYHLDCSCQK
                     LDLHYHLLQAQTEMLFASYHLELSWD"
     gene            14748..17429
                     /locus_tag="VB649_000970"
     CDS             14748..17429
                     /locus_tag="VB649_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEP1669929.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLETSREGLTSAQAKERLAEYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILIVAALLSVLTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARIRRDGHVTEIDSKELVPGDIVLLEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSTAVSEDAGIGDRVNMGYQNSNVTYGRGIGVIT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQH
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQSSSADIAFDNTTLRVMNFANDTKVDPSGKLIGDP
                     TETALVQFGLDHNFDVREAMVAEPRVAELPFDSDRKLMSTIHKQADGKYFIAVKGAPD
                     QLLKRVTQIEENGQIRPITDADKKTILDTNKSLAKQALRVLMMAYKYSDALPTLETEI
                     VEANLVFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAKAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRKSSFFDGGVKEAILYQGAFQTMLVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNQFFHVTH
                     LTITQWLVVIIGSLLMVVLVELVKAVQRSLGQDEKAI"
     gene            complement(17513..18508)
                     /locus_tag="VB649_000971"
     CDS             complement(17513..18508)
                     /locus_tag="VB649_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEP1669930.1"
                     /translation="MQRKVTIKDIAELAKTSKTTVSFYLNGRFDKMSEETKNRIKSTI
                     EATNYKPSIAARSLNAKSTKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIDIKKKKVVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCIDKGYEHFIMITGNPNLLSTRIERASGFIDVLEANHLTHQEMI
                     IDENQTSSEAIAQFLQGSLTKKSLVFVPNCWALPKVFTAMKSLKFNIPEIGLVGFDNI
                     EWTKFSSPTLTTIIQPAYEEGEQATKILIDDIEGHSQEAKQQIFDCQVNWQESTF"
     gene            complement(18572..20479)
                     /locus_tag="VB649_000972"
     CDS             complement(18572..20479)
                     /locus_tag="VB649_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEP1669931.1"
                     /translation="MSLAFTRFKETVNPDFCRNYLLDYQADSYADRKRIADLLLTNTF
                     LFEDNWDMEPCHIPYHLDPITWQKAVTDDPEWNFMLNRQTYLQTLILVYLVERDERYL
                     LKAKSFILNWIESAIPLDPKGLATRTLDTGIRCFAWVKCLIYLNLFDALTKQEERLIL
                     ASLEKQLHFLHANYLDKYSLSNWGILQTTAILLADAYFGSDLDIAAATAFARKELTQQ
                     IALQILEDGSQFEQSTMYHVEVLKALLELTALVPDYLPQLRPTLLAMSDYLLKMTGPD
                     HKQIPLGDSDFTDTRDILTLAATILEEPHLKAAAFPTLDIDSLLLLGEKGVHTFEQLP
                     VQTLPTFAHHFEHSGHITINQENYYLFFKNGPIGSSHTHSDQNSICLYYKGQPLFCDA
                     GRYTYKEEPLRYALKSASHHSTAFLEEQLPEQIDSSWAYLSYPKSNYCHLRQNGHVYF
                     IEGSYQTQFSDRNNYQHDRQILILPPGILLIIDTIQAQGNHCLVSQFILDNHLEVKTD
                     HLSDLRLISDCPFTIEETILSKKYNQYLTSHKLIKRKPFKDKGYTSTLLVPDDTKVTP
                     LTPLQTGKRNPIETALSWHLKGKQFDYSICVLQEDLIKGEKLVLLNSHKIRGKVVVIN
                     HITNEIIRLKH"
     gene            complement(20566..21387)
                     /locus_tag="VB649_000973"
     CDS             complement(20566..21387)
                     /locus_tag="VB649_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP1669932.1"
                     /translation="MTGSNKLTKKDYLKTALRAFFLQNGFNYSNYQGIGYANVIYPAL
                     KKHFGSDKKGLYQALEDNCEFYNTNPHFFPFITSLHLVMLENDRPEEETRNIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASLASDGLVLGPIFFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAVVSRMANIVGVTVIAGLAATSVKITVPITFAAGKVDAANTAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKNKKWTTYKLVLLTVLIGIIGSWLGILA"
     gene            complement(21374..22156)
                     /locus_tag="VB649_000974"
     CDS             complement(21374..22156)
                     /locus_tag="VB649_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEP1669933.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGMILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFAYTAFAGAPETAKKQLQKGNIRGFKFAANGTIWSFAILGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEFYNKPKQVDATTVQGGQQDDWI"
     gene            complement(22175..22663)
                     /locus_tag="VB649_000975"
     CDS             complement(22175..22663)
                     /locus_tag="VB649_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEP1669934.1"
                     /translation="MTQPNIIMTRVDERLIHGQGQLWVKFLNCNTVIVANDAVSEDKI
                     QQSLMKTVIPSSIAIRFFSIQKVIDIIHKASPAQNIFIVIKDLQDAKRLVEGGVPITE
                     INIGNIHKTDDKVAITQFISLGETDKSAIRCLAHDHQVVFNTKTTPAGNSASDVDILD
                     YI"
     gene            complement(22699..23898)
                     /locus_tag="VB649_000976"
     CDS             complement(22699..23898)
                     /locus_tag="VB649_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEP1669935.1"
                     /translation="MTRSLKTIALEPIKQPERFTKEDFLSQEDITQALDLALKQVRLN
                     MDYFKEDFPTPATKDNQYAIMDNTEWTNAFWTGCLWLAYEYSGDDAIKALAQANDLSF
                     LDRVTRDIELDHHDLGFLYTPSCMAEWKLLKTPEAREAALKAADKLVQRYQDKGGFIQ
                     AWGELGKKEDYRLIIDCLLNIQLLFFASQETGDNRYRDMAINHFYASANHVIRDDASA
                     YHTFYFDPETGDPVKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKEPELIQLFKGM
                     THYFLNRLPKDQVSYWDLIFGDGSEQSRDSSATAIAVCGIHEMLKTLPDHDPDKKTYE
                     AAMHSMLRALIKDYANKDLKPGAPLLLHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWNPYW"
     gene            complement(23898..24335)
                     /locus_tag="VB649_000977"
     CDS             complement(23898..24335)
                     /locus_tag="VB649_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP1669936.1"
                     /translation="MIAIIVMGHGHFASGIVSSLELIAGPQEKVTAIDFTAEMTAADV
                     QDQLSRALIPEEETLVLCDLLGGTPFKVAATLMESLPNTTCNVLSGLNLAMLIEASFA
                     RQTAASFDDLVSGLITCSKEGIVDWKTLSQQEDGTTDDELGGI"
     gene            24669..25463
                     /locus_tag="VB649_000978"
     CDS             24669..25463
                     /locus_tag="VB649_000978"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEP1669937.1"
                     /translation="MENMFSLQGKIALITGASYGIGFEIAKAYAQAGATIVFNDIKQE
                     LVDKGLAAYRELGIEAHGYVCDVTDEAGIQQMVSQIEDEVGVIDILVNNAGIIRRTPM
                     LEMAAEDFRQVIDIDLNAPFIVSKAVLPSMIAKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTTEDLAGPAVFLASDASNFVNGHILYVDGGILAYIGKQP"
     gene            25488..26129
                     /locus_tag="VB649_000979"
     CDS             25488..26129
                     /locus_tag="VB649_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEP1669938.1"
                     /translation="MKIALINENSQAAKNGIIYDALTTVTDKHGYQVFNYGMYGTEGE
                     SQLTYVQNGLLASILLTTKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     SQINGGNALSIPFAKGFGWGAELNLTLIFERLFAEPTGGGYPKERAIPEQRNARILSD
                     LKKITYRDLLAIVKDIDQDFLKETISGAHFKEYFFANAEPSELVTYLKSVLEQ"
     gene            26158..27159
                     /locus_tag="VB649_000980"
     CDS             26158..27159
                     /locus_tag="VB649_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEP1669939.1"
                     /translation="MSKLLLVGEPLIRVSPNQFQPLTNACDAQLFFGGSEVNIARTLG
                     GFGLEARLFTALPDNPVGHAFHQFLKQSGVDMTLTAWQGNRVGLYYLENGFGCRSSQV
                     YYDRCGSSFSALDKDSLDLAAIFEGISHFHFSGISLALGKKTQDLIEVLVREAKKRDI
                     CVSFDLNFRSSMIAVADAKRLFSHFAQYADIIFGMEPLLLDSDDFDMFDRNKADATMI
                     RERLAGLYQRYQLQAIYHTERSNDAQGSNRFKAYAYDGQFYESCEVTTPVLQRVGSGD
                     AFVAGLLYQLLEGNEKQCNLDFAVATASLKCTVAEDQLYHSVQQVEAVLHNQRDVQR"
     gene            27164..27799
                     /locus_tag="VB649_000981"
     CDS             27164..27799
                     /locus_tag="VB649_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEP1669940.1"
                     /translation="MGKIEILTKLKANRLVLVVRGESSEEALACSLASIEGGIKTIEV
                     TYTNPFASEVIGQLAERFKEDPEVLIGAGTVLDDVTARQAILAGAQFIVGPNFNRAVA
                     LICHRYSIPYLPGCMTVNEVVTALESGVDMVKIFPGSTVGISFIRAIKSPLPQVEVMV
                     TGGVSSDNLKDWLAAGVDVLGIGGEFNQLASQKQYNLITKKAAHYIKSLRQ"
     gene            28096..28746
                     /locus_tag="VB649_000982"
     CDS             28096..28746
                     /locus_tag="VB649_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEP1669941.1"
                     /translation="MIKGIIFDMDGVLFDTEPFYLRRREDFFKTKGIPIDHLNSKDFI
                     GGNLQELWKELLGKNRDDAIVKAITTDYDAYKQAHKPPYQKLLITEVNSCLEQLKKQG
                     IKLAVASNSKRQDVLLALETTQIKDYFEIILAREDVSRGKPYPDIYNKAVQKLGLQKK
                     QLLVVEDSQKGIAAAKAANLTVFAITDYRYGIDQSQADHKIDHLGQLCVKIGCFGS"
     gene            29442..30566
                     /gene="queG"
                     /locus_tag="VB649_000983"
     CDS             29442..30566
                     /gene="queG"
                     /locus_tag="VB649_000983"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HEP1669942.1"
                     /translation="MTIKAEIKALAKEIGISKIGFTTADNFDYLEKSLRASVEEGRNS
                     GFEHKVIEDRISPERLLESAKTIISIGVAYPHKLPQQPQKTPYKRGKITPSSWGFDYH
                     YVVGEKLERLPKGIEELCRDFPLQQKAMVDTGALVDTAVAQRAGIGFIGKNGLVISKE
                     YGSYMFLGELITNLEIEPDNPVDYDCGDCRRCLDACPTSCLIGDGSMNAKRCLSFQTQ
                     DKGMMDIEFRKKIKTVIYGCDICQICCPYNKGINNSPATEIDPELAQPELIPFLSLSN
                     GKFKEKFGMIAGSWRGKNILQRNAIIALANAHDKTAVVKLIEIIDKNNNPIHTATAIW
                     ALGEIVKKPNDEILAFMSHLTLKDEDSRKELELIRHKWQF"
     gene            30635..31733
                     /gene="prfB"
                     /locus_tag="VB649_000984"
     CDS             join(30635..30706,30708..31733)
                     /gene="prfB"
                     /locus_tag="VB649_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889043.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEP1669943.1"
                     /translation="MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENHMTEPD
                     FWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQ
                     LDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVE
                     VMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFELAQVDKVMDGEINGFIDAYLKWRIED"
     gene            31752..32444
                     /gene="ftsE"
                     /locus_tag="VB649_000985"
     CDS             31752..32444
                     /gene="ftsE"
                     /locus_tag="VB649_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEP1669944.1"
                     /translation="MALIEMSGVTKKYRRSTTALRDVNVSVNQGEFVYLVGPSGAGKS
                     TFIKLLYREEQLTTGKLYVGEFNLTKLKARDVPILRRHIGVVFQDYKLLPRKTVFENV
                     AYAMEVIGEKRRHIKKRVPEVLDLVGLKHKMRSFPSQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMQLLERINVQGTTILMATHNSHIVNTFRHRVVAIEDGRIV
                     RDEEKGDYGYDD"
     gene            32437..33366
                     /locus_tag="VB649_000986"
     CDS             32437..33366
                     /locus_tag="VB649_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669945.1"
                     /translation="MIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATL
                     LNIQRVASGVENNVHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVK
                     KITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEG
                     VEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIM
                     RLVGAKNSYIRGPFFFEGAWVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPL
                     DPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF"
     gene            complement(33676..34374)
                     /locus_tag="VB649_000987"
     CDS             complement(33676..34374)
                     /locus_tag="VB649_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP1669946.1"
                     /translation="MPFIFRHSFFNKALIFWYTILMKIYKTINHIAGENTYYLVNDQA
                     VILIDPGSNGQEIIAKIKSFEKPLVAILLTHTHYDHIFSLDLVRDAFDHPPVYVSEKE
                     AAWLSSPDDNLSGLGRHDDIITVIARPAENFFKLKQPYQLNGFEFTVLPTPGHSWGGV
                     SFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTLPNHYRVYPGHGPS
                     TTICHEKNANPFFH"
     gene            34542..35306
                     /locus_tag="VB649_000988"
     CDS             34542..35306
                     /locus_tag="VB649_000988"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HEP1669947.1"
                     /translation="MSKVAIVTGAGQGIGFAIAKRLHADGFKIGILDYNEETAQAAVD
                     KLSPEDTVAVVADVSKRDQVFDAFQKVVDTFGDLNVVANNAGVAPTTPLDTITEEQFE
                     KAFAINVGGTIWGSQAAQKHFRELGHGGKIINATSQAGCEGNPNLTVYGGTKFAVRGI
                     TQTLAKDLASEGITVNAYAPGIVKTPMMFDIAHEVGKNAGKDDEWGMEQFAKDITLKR
                     LSEPEDVANAVGFLAGDDSNYITGQTIVVDGGMVFH"
     gene            35414..37915
                     /locus_tag="VB649_000989"
     CDS             35414..37915
                     /locus_tag="VB649_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEP1669948.1"
                     /translation="MFCFIDIACYNRLTMTQKKLRKYAVVDLEATGAGPNASIIQVGI
                     VIIQGNKIIDSYETDVNPHESLDEHIVHLTGITDKQLAKAPDFGQVAHHIYQLIEDCI
                     FVAHNVKFDANLLAEALFLEGYELTIPRVDTVELAQLFFPRFEKYNLGHLSRQLNIDL
                     AEAHTAIADARATAILFLRLLQKIESLPIECLESLLVYSDSLLFETAMVIQEGLAKAK
                     PYDPNKYIKIRQILLPKGSKALKPYQISKSFPINMALLGLEERPKQTQFAQLIDEDYH
                     QGVASFIEAQTGIGKTYGYLLPLLAKEDQNQIIVSVPTKLLQDQLMAGEVAAIQEQFH
                     IACHSLKGPANYLKLDSFADSLDQNDQNRLVNRYKMQLLVWLLETKTGDLDEIKQKQR
                     FAAYFEQLKHDGDIKQSSEFYDYDFWRVSYEKAKTARLLITNHAYFLHRVQDDKDFAR
                     NKVLVFDEAQKLMLQLDQLSRHQLNLTVFLQTIQAKLSNPLPLLEKRLLESLSFELGQ
                     VSSDYYQNKEHQLAHDWSRIAGYAKELTGADYQELQAFFATSDGDYWLSSEKQEEKRV
                     TYLNSASKAFIHFQQLLPETVKTYFVSATLTISSEVTLADLLGFEEYLYHVIEKDKKQ
                     DQLVLVDQEAPIVTEVSDQIYVEAIAKRIESLKQEGYPILVLFNSKKHLLLVSDYLDQ
                     WQVPHLAQEKNGTAYNIKKRFDQGEQTILLGLGSFWEGVDFIQADRMITLIARLPFDN
                     PEDFFVKKMSHYLLEKGKNPFRDYFLPMTILRLKQAIGRTMRRQDQKSVVIILDRRLL
                     TKSYGQVILEGLGQEFLISQQNFHDCLVETDCFLI"
     gene            38250..39443
                     /locus_tag="VB649_000990"
     CDS             38250..39443
                     /locus_tag="VB649_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEP1669949.1"
                     /translation="MPKLSKRVLEMKESVTLAAGARAKALKAQGRDVLNLTLGEPDFF
                     TPKHIQDKAIESIQNGTASFYTNASGLPELKVAIATYLKNQYGYHLSPDQIVAGTGAK
                     FILYAFFMAVLNPGDQVLIPTPYWVSYSDQVKMAEGQPIFVQGLEENQFKVTVDQLER
                     ARTSKTKVVLINSPSNPTGMIYGAEELRAIGEWAVHNDILILADDIYGSLVYNGNQFV
                     PISTLSEAIRRQTITVNGVAKSYAMTGWRVGFAAGEPEIISAMSKIIGQTTSNLTTVS
                     QYAAIEAFCGSQSSLEEMRLAFEERLNITYPLLCQVPGFEVVKPQGAFYFFPNVKKAM
                     EMTGFSDVTSFANAILEEVGLAVVSGAGFGAPENVRLSYATDIETLKEAVRRLHVFME
                     SNEIN"
     gene            39464..40810
                     /gene="asnS"
                     /locus_tag="VB649_000991"
     CDS             39464..40810
                     /gene="asnS"
                     /locus_tag="VB649_000991"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEP1669950.1"
                     /translation="MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSA
                     FFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITN
                     LEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDKNGF
                     IKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVE
                     ALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP"
     gene            41224..42114
                     /gene="rapZ"
                     /locus_tag="VB649_000992"
     CDS             41224..42114
                     /gene="rapZ"
                     /locus_tag="VB649_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEP1669951.1"
                     /translation="MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPK
                     FLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVS
                     RYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFS
                     GGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVELREKTGLDKDVFNYVM
                     SHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATD
                     WSVNESHRDQNRRKETVNRS"
     gene            42111..43088
                     /locus_tag="VB649_000993"
     CDS             42111..43088
                     /locus_tag="VB649_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEP1669952.1"
                     /translation="MKNPKMTVIGGGTGISIILKSLRNEAVDITAVVTVADDGGSSGE
                     LRNAMQLAPPGDLRNVLLAMSDMPKFYERVFQYRFNESDGALAGHPLGNFIIAGISEM
                     QGSTYNAIQILTKFFHITGKIYPSSEQALTLHAVFKDGHEVAGESSIAKYQGMIDHVY
                     VTNTYNDQKPQASRKVVEAILESDMIVLGPGSLFTSILPNLVIPEIKEALRQTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVAKVPQAYMNSNKFDEYLV
                     QVDHDFAGLCRAAKRVISSYFLRLENGGAFHDGNLVVEELMNLVRIVKQ"
     gene            43085..43996
                     /gene="whiA"
                     /locus_tag="VB649_000994"
     CDS             43085..43996
                     /gene="whiA"
                     /locus_tag="VB649_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEP1669953.1"
                     /translation="MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSIT
                     TENAKIARYIYSFIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADS
                     FFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMQKFMLDAKTIEHKSGAVTYLQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDIN
                     RANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQV
                     ADALEFPITKSGVNHRLRKINKIADDL"
BASE COUNT        13288 a         7874 c         9411 g        13538 t
ORIGIN      
        1 ttgcaaggaa aatctaagac ctcaaatccc ttgtcatggt atgtgtcata tagtgcttgc
       61 aaggcctggt attgtggggt taatccacac ttggtagctg tgttaacaat caaaacaacc
      121 ttttttttat aagcagctaa ggaaaggtca ttcccgtttt gagccttaac cgtaaaatca
      181 tagagattag gcatgtgaca tctcctcggt gtaactgata atttggtcaa cggtctcact
      241 caagaattga atggtatctc gaagaggttt ttcagtagca atgtctgccc caatgagcat
      301 tgcagtatca agaggcgtac ggctgccacc tgattttagg aagtcaagcc attcttctgc
      361 cccatctggg ttgtttttaa ggttgaggta accagctgtt gaaataacaa gaccagcaga
      421 ataggtataa ctatataagc ccatgtagta atgcgcttgg cgcatccagg taagagctgc
      481 gtcatcgtcg atgtcaacgg catctcccca gaagtctgtt aagacctctt tcatcatcgc
      541 atttaattgg tcagctccaa aggtaccgcc ttcttcaatc agggtgtaaa ccttacgttg
      601 gaaagtcgct tccaataggt gagtgatgaa gttatgaaag taagtgtctg ttaaacggtg
      661 agcaagggaa aaacgttttt gacgagggtc atcaaattga tgttccaagt aatcactaag
      721 catcaattca ttaaaggtcg atggcgcttc gacgtaataa gttgacatat gggtgttgaa
      781 gtaactttgg tgattatcag agaaaataaa ttggccagag tgtccgattt catgaatgag
      841 cgtgtagaca tcagacattc tgccagtcca gctcattaag acatacggat ggaccttgta
      901 aggatcagcg gcataaccac cagaatcttt attggcatta gcagcaaagt caacccagcg
      961 ttctgtctga taacgttcga tttctttcgt gtattcttgt cctaatgggg ctagagattt
     1021 catcacgagg tcataagcgc catcaatgct gacctctgga ttgagctcat tatcaatatc
     1081 tagtttccag tcagcaaaag tcattttctc aagaccattg acttgggcga catgttttaa
     1141 gaatttctga gcaaccggtc caaattcagt catgatgagg tcaatttggc ggtcgaacaa
     1201 gctacgatcc acttcctgtt cagctaggag gtaatcaaag acagaagcgt agcctttcat
     1261 atcagctaac aatttttcag atttaacctt ggctaagtaa gccgctgcag ctgtattttg
     1321 gtgtttacgg agaccttttg aaaaagagcg gaaggctttt tcacgaatct cagcattttc
     1381 gtgattttga tagaaatttt cgtaagaaac aaagctattt ttataggttt taccatccac
     1441 ctcaaaatca tccatgtcaa agtcaccagc ccgcattttg gtgtaaatat catagggcgc
     1501 attgataacc tcgcgtaagt tagccaaagc tttttccaca tcaggactta agaggtgttc
     1561 tttttgaatt tttgccatgc gaatagctgc gctgaaataa gggttctttt ctaatgtatc
     1621 taacacgtca aggtcggcat tggctaaggc ggtgtcaaag aagctaaggg caacgctagc
     1681 tttagtcatg aaatcatcgc cagcctgagc aatttgagca aaactttcat ctgaaaagtc
     1741 agtggtttga ggcataaagg cataagtgcc aatatgactc atttgaatat aaatatgctc
     1801 aatttctatt aaggcctgag tgaaatcgtc caccgacgtt aagcggcctt cataattgcg
     1861 cttaaacagg tcaatatctt gtaaggcttt ttcaatagcg agtaaaaaat cttggcggtc
     1921 tttgtagagc gctgttagat cccaaagttc attttcaggg aattctgaac gttttttcaa
     1981 ttccatagtt gtctccttaa caatatagtc aagactagta taacagaatt ttagtggaat
     2041 atggagacta aacctatcca aacattcttt aaaataaagc gcttactttt gttaaaaaac
     2101 aaacgttatg aacatgatca cttttatttt tggtaaaaag tggtatgata gaagaaacta
     2161 gcaaagaagg agatggtcat ttgccactta aaaagttaga gagtagtaac aatcaagata
     2221 tcattgctga agaagttgct cttttgaaag aaatgttgga aaatatcaca cgacggatga
     2281 ttggagatga tgcgtttaca gttatcgagt ctattatggt gttatctgaa aaacaagatt
     2341 acatagaatt agaaaaagtt gtcgccaata tttcaaatca agaaatggaa gtgatttcca
     2401 ggtatttttc tattttaccc ttgctaatca atatttcaga agatgtcgat ttagcctatg
     2461 aaatcaatta tcaaaataat acggatactg attatttagg aaaattagcc ctaaccatca
     2521 aggatcttgc tggaaaagat aatggtaaag acattttgga gcaggttaat gtggttcctg
     2581 ttttaacagc acatccgacg caagtacaac gtaaaacgat tctggaattg acaactcaca
     2641 ttcataaact tctgcgcaaa taccgtgatg ctaaggctgg tgtgattaat cttgagaaat
     2701 ggcgtcagga gctatatcgt tatattgaaa tgatcatgca gacagatatt attcgcgaga
     2761 aaaagcttca ggtgaaaaac gagataaaaa atgtcatgca gtattacgat ggttctctca
     2821 ttcaagcagt gaccaagttg acaacagagt acaaaaactt agcccaaaaa cacggtctag
     2881 agttagacaa tcccaaaccc attaccatgg ggatgtggat tggtggggac cgtgatggga
     2941 acccctttgt cacagctgaa accttgtgct tgtcagctac ggttcaaagt gaggttatcc
     3001 tcaattacta cattgacaaa ttagcagccc tttaccgaac attttcactg tcgtcaacct
     3061 tggtacaacc caactcggaa gtggaacgtt tagccagttt gtctcaggac caatcgattt
     3121 accgtggaaa tgaaccttat cgcagagctt ttcattatat tcaatcgcgt cttaaacaaa
     3181 cacaaattca actaactaat cagccagcag ctcgtatgag tagtagtgtg ggactaaaca
     3241 catctgcttg gccctcacca gctagtttag aaaatcccat cttagcctat gactctcctg
     3301 ttgattttaa agctgattta aaggctattg agcagtcgct acttgataat ggcaactccg
     3361 ctttgattga gggggatttg cgagaagtca tgcaagctgt tgatattttt ggcttcttct
     3421 tagcaagcat tgacatgagg caagactcca gtgtccaaga agcttgtgtg gcagagttat
     3481 taaaaggagc caatattgtt gacgattata gctctctttc agaaactgaa aaatgcgatg
     3541 ttctcttaca acaattaatg gaggagccaa ggactttatc ctcagcggca gttgctaaat
     3601 cagacctatt ggaaaaagaa ctggctatct atactacggc acgagaattg aaagataagc
     3661 ttggagaaga ggttattaaa caacatatta tttcacatac agaaagtgtc tctgatatgt
     3721 ttgagttggc catcatgctt aaagaagtgg gattggttga ccagcagcgg gctcgtgtgc
     3781 aaattgttcc cctctttgaa accattgagg atttagataa tgcccgtgac atcatggcag
     3841 cctatttaag ccatgacatt gtcaaatctt ggattgcaac gaatcgtaat taccaagaaa
     3901 tcatgttagg ttattctgac agtaataaag atggtggcta cttggcatcg ggttggactc
     3961 tttataaagc tcagaatgaa ttaacggcta ttggtgagga acatggagtg aaaatcacct
     4021 tcttccatgg tcgtggagga acagttggtc gaggaggtgg cccttcttat gatgccatta
     4081 cttcacaacc ttttggttcc atcaaagatc ggattcgtct gacagagcaa ggggaaatta
     4141 ttgaaaacaa atacggcaat aaagatgtgg cttattacca tttagaaatg ttgatttcag
     4201 cttctatcaa tcgtatggtg actcaaatga taacagatcc taatgagatt gatagttttc
     4261 gagaaatcat ggatagcatt gttgctgata gcaataccat ttatcgaaaa ttggtttttg
     4321 acaatcccca tttctatgat tatttctttg aggcaagccc gattaaggaa gtttccagtc
     4381 tcaacattgg gtcaagacca gcagcccgta aaacgattac ggaaattaca ggcttgcgtg
     4441 ccattccttg ggtcttttca tggtcacaaa atcgcatcat gttcccaggt tggtatgggg
     4501 taggttcagc ctttaaacgt tatattgacc gagcacaagg taaccttgaa cgcctccaac
     4561 acatgtatca gacgtggcct tttttccatt ccttgttatc aaatgttgat atggtattat
     4621 ctaaatcaaa catgaatatt gcctttcagt atgcacaact agctgaaagt caggatgttc
     4681 gagatgtttt ttatgagatt ttggatgagt ggcaattgac aaaaaatgtt attcttgcta
     4741 tccaagacca tgatgatcta ttggaggata atccttccct taagcatagc ttgaagtcac
     4801 gcttgccgta ttttaatgtg ttgaactata ttcaaattga attgattaaa cgttggcgta
     4861 ataatcaact tgacgaaaat gatgaaaaat tgatccatac aactatcaat ggcatagcga
     4921 ctggtttacg taattcaggc taatgctctt gagtattaat tggtatttat agaagttttc
     4981 aagtgactaa tcagaatttt aaaggttagc ccttggagct tctttttttg aggattcttg
     5041 acttttcctt ttgtttgata tagaaagatg ttataatgct aaatgattat ctcaagaagt
     5101 agagggaaaa ctatgaagat tgataaaagg cacctcttaa attattctat attattgcct
     5161 tatttaattt tatcggtgat aggcttaata atggtttact caaccacaag tgtcagcttg
     5221 attcaagcac atgctaatcc atttaaatcg gtgattaacc agggagtttt ttggataata
     5281 agtctagtgg ctattacatt tatctataaa ttaaaattaa attttttaac gaatacaagg
     5341 gtattaactg tggttatgtt aggagaggcc tttcttttaa tcattgcccg cttctttaca
     5401 actgctatca aaggagcgca tggttggatt gtgatcggac cagtcagctt tcagcctgct
     5461 gagtatttaa agatcattat ggtatggtat ttggcattga cctttgctaa gatccaaaaa
     5521 aacattagcc tttatgatta tcaagcacta actcgtcgaa aatggtggcc aacacaatgg
     5581 aacgatttac gggactggcg tgtttattct ttgttgatgg tacttttggt tgctgctcag
     5641 cctgacttgg gaaatgcttc cattattgta ttgacagcca ttattatgtt ttctatcagt
     5701 ggcattggtt accgatggtt ttcggctatc ctagtcatga ttaccggtct atccacggtc
     5761 tttcttggga ctattgccgt tattggggta gaaagagttg ctaagattcc tgtttttggc
     5821 tatgtcgcta aacgttttag tgcctttttt aatcctttcc atgacttgcc cgattcaggt
     5881 caccaattag ccaattctta ctatgctatg agtaatggtg ggtggtttgg ccaagggtta
     5941 ggaaattcca ttgaaaagcg tggctatttg cccgaagcac agacagactt tgtcttttca
     6001 gttgtcattg aagagttagg tctaatagga gcagggttta ttttggcact tgttttcttc
     6061 ttaattttac gtattatgaa tgttggtatt aaagcaaaaa atccttttaa tgccatgatg
     6121 gctttaggag taggcggtat gatgctcatg caagtctttg ttaatattgg tggtatctca
     6181 ggcttaattc catctactgg tgttaccttc ccttttttgt ctcaaggtgg aaatagctta
     6241 cttgtcttat ctgttgcagt gggttttgta ctaaatattg atgctagcga aaagcgagat
     6301 gatatattta aagaagctga attatcttat cgaaaggaca ctcgaaaaga aaatagtaaa
     6361 gttgtaaata tcaagcaatt tcaataatat tctaaaatct cctttaagga gattttagaa
     6421 tatagacaat cccagtttga tgctcaaaaa acttgaactg ctctgctgat ttcttatttt
     6481 tgcgtgtgac atgagcccaa acagctgctt tttgctgtgg caaaaataag gcgtggaatt
     6541 ccaaaggaag tcgctgctat aagcaccacc taaggagagt atcgaaaaag actttttctt
     6601 ctatttaaaa aataaagaaa tggcaaaaaa cataaaatac ttgcattttc attgtaattt
     6661 gctacaatag taaggtaaag ttagactgta tggcctaccg tctatctata aaatatattt
     6721 tattggaggc ttttcctaaa atggcaaaag aaaaatacga tcgtagtaaa ccccacgtta
     6781 acattggtac aatcggacac gttgaccatg gtaaaactac tttaacagct gcaatcacaa
     6841 ctgtattggc acgtcgcttg ccttcatcag ttaaccaacc aaaagattac gcttctatcg
     6901 atgctgctcc agaagaacgc gaacgcggaa tcactatcaa cactgcacac gttgagtacg
     6961 aaactgcgac tcgtcactat gcgcacatcg acgctccagg acacgcggac tacgttaaaa
     7021 acatgatcac tggtgccgct caaatggacg gagctatcct tgtagttgct tcaacagatg
     7081 gaccaatgcc acaaacgcgt gagcacatcc ttctttcacg tcaggttggt gttaaacacc
     7141 ttatcgtgtt catgaacaaa gttgaccttg ttgatgacga agagttgctt gaattagttg
     7201 agatggaaat tcgtgacctt ctttcagaat acgatttccc aggtgatgac cttccagtta
     7261 tccaaggttc agctcttaaa gctcttgaag gcgacactaa atttgaagac atcatcatgg
     7321 aattgatgga tactgttgat tcatacattc cagaaccaga acgcgacact gacaaaccat
     7381 tgcttcttcc agtcgaagac gtattctcaa ttacaggtcg tggtacagtt gcttcaggac
     7441 gtatcgaccg tggtactgtt cgtgtcaacg acgaaatcga aatcgttggt atcaaagaag
     7501 aaactaaaaa agctgttgtt actggtgttg aaatgttccg taaacaactt gacgaaggtc
     7561 ttgcaggaga caacgtaggt atccttcttc gtggtgttca acgtgacgaa atcgaacgtg
     7621 gtcaagttat tgctaaacca ggttcaatca acccacacac taaattcaaa ggtgaagtat
     7681 atatcctttc taaagacgaa ggtggacgtc acactccatt cttcaacaac taccgtccac
     7741 aattctactt ccgtacaact gacgtaacag gttcaatcga acttccagca ggtacagaaa
     7801 tggttatgcc tggtgataac gtgacaatca acgttgagtt gatccaccca atcgccgtag
     7861 aacaaggtac tactttctca atccgtgaag gtggacgtac tgttggttca ggtatcgttt
     7921 cagaaatcga agcttaattt taattaagtt cccagaatag caatttaagt cagacaactt
     7981 aagtttgaag aagcccccaa ttcgggggct ttttgctatc ttaaactcca taaaatgctg
     8041 ataaataaga atgaaaagct ttcagaaaaa gggtttttat ttgtgaaaat attcctaaaa
     8101 tataagcaat tccttttaat cgtcggtcat ttgtgctaaa atagaagata taaataaaaa
     8161 aagaagaggt atgtgatatg tcacgtaaac caattattgc tggtaactgg aaaatgaaca
     8221 aaaaccctca agaagcaaaa gcattcgttg aggctgtagc aagcaaatta ccttcaactg
     8281 accttgttga tgttgccgta gcagccccag ctgttgattt ggtaaccact gttgaagctg
     8341 ctaaagattc agttcttaaa gttgctgcac aaaactgcta ctttgaaaac acaggggcat
     8401 tcactggtga aacatcacca aaagtgcttg ctgaaatggg agctgactat gttgtgattg
     8461 gtcactcaga acgccgtgat tacttccatg aaacagatga agacattaat aaaaaagcca
     8521 aagcaatctt tgctaacggt ttaactccaa ttgtttgttg tggtgagtct cttgaaactt
     8581 atgaagctgg taaagccgtt gagtttgtag gtgcgcaagt ttcagcagca cttgcaggtc
     8641 tttcagcaga gcaagtagct tcacttgttt tagcttatga gccaatctgg gctatcggta
     8701 ctggtaaatc agctactcaa gatgatgctc aaaacatgtg taaagctgtt cgtgatgtgg
     8761 tagcagcaga ctttgggcaa gaagttgctg ataaagttcg cgttcaatac ggtggttctg
     8821 taaaacctga aaacgttaaa gattacatgg cttgtccaga tgttgacggt gcccttgtag
     8881 gtggtgcatc acttgaagct gatagcttcc ttgctttgct tgatttcctt aactaagcca
     8941 tctaaaaaag aaaaggttaa atccttttct tttttagatg acttcactct tactataaga
     9001 gaataaaggt gattctacag gcaaatgcat tagcctaata gcggtttaat agcttttttg
     9061 ccaatctaat gaaatgatat ttgattggaa atggataaca tctaaatgtc cctggttttt
     9121 gcaaaataaa gccattgaaa ttctgtttaa agcgcaagac accgtctgaa ccatcaaact
     9181 ttccagtaat accaagaaaa ttatattgtt tgatgccctt gtgaattgcc ttgagcatag
     9241 catgctcttg taatagagct gggctataaa atttattaaa tttggggtaa gatcctgaaa
     9301 agaggtagac ggcctcttgt tcggtataga taaaaagact tcccgcaagg aacacatctt
     9361 tagttccata ctcttcaaga aaatggagag cttcagaaat tcttacctga aaggtttcga
     9421 attggctgga tagttctttt aatctatttt gctttttttc agaatgagga tttttgccaa
     9481 ggtctccttt aactttgttg atgctggttg ctagttgtag ttgtctttgt ttaaggttat
     9541 taaggtaatc ttcaaaatta agagtcgcaa ccataaattc acaagagtct ccaaaactat
     9601 cataaaagtc ctgatagtaa gataatgatt tgtcaaggta atctctacga tcagaggttg
     9661 cttcagtgat ttctttgaaa tggtgtaact catctcgttt cagttgacgt aatttaatac
     9721 caaaagtatt agcttttttt attaaagctt ttcctttttt gctgaaggaa tgggttaaac
     9781 gtgaggaatc aattccttct aactttttaa cgtaatgcca aacaggttca ccctcaggat
     9841 agcctgtttt taaaccgtca tgtttatatc ctaacgccgt taaaaggcta ataaggtcag
     9901 tgtttggatg agaaataggg atgccatcag tatcaaatga ctgataattg tcgtaaggtt
     9961 ttaaaatgag ttcgataacg tctttttgtt tggcatagtc tttaagttga gtgtaaaaat
    10021 gttctaattc ttcgggatga ttggtattag ggcctgcatt gagttccata cgccaacctc
    10081 cagccacttt ttggctaaag accatagcag caacctttag ttcaccatct ttttcaagtc
    10141 caagaaattg tggttttgcc cctcttttag ccatcaagct ggccatttct gaggtttgga
    10201 taaaggaatg atggacgaga ctgtggcagt aatagtcaaa ttgttcttgt gaaatttcaa
    10261 ttagtgccat tagttgtgct ccttaatttt tttcttaagt tataggtcaa gatggctaag
    10321 cttgaaacaa ggccgacagg aatgttgaat tcacctgcaa attcttcgat ggtggggttg
    10381 agtctagctt tgaaatgata gagtccacca tcttgttgat tttccacacc tcctaaatta
    10441 tgccagcggc agcctctttt aaaagcttct ttagccgttt cataccaggt taaaagagga
    10501 gcttgataat tgcgataatc atcgtccatt cccgcataaa gattttcaga agtctctcca
    10561 taaatcaagg ttagggtggc ggctagtggg atgcgggttt tgcctgcagc gagctgctcg
    10621 cttaaaatgg ttaaatcttt ttgtagccgt gcaatggttt tttgattttc tgctactttg
    10681 ctaggtttac tcttatctgt taatcgtgct tgttctgcta aggccttgtc caactgttgg
    10741 atcaagagtt ttttttgttc aggtaagtct aaactagcca tagtaatgta ggactgacca
    10801 gcataaatat ctagtaattt ttgatagtag gatttgcctc ggaggataat gccttttcga
    10861 ttctcggttt ttttcatcaa ggctgaaaag tcgtctagca attcactgcc accaatcgtg
    10921 acattaacac ctttattggt agcggtacga atggattgct tggctttttt gggcaggctg
    10981 tcaaagtcaa aatccttggc gtagatgttg gcttgtattc ttggttgaat agtgtcttcg
    11041 agttcttttg ttctgccaga ccattcgaca ccgagttttt ttagaaaagc aataatagag
    11101 agtgtcacat cattttcttt gctctctttt ccttctaaag tttgtttgat gactaaactt
    11161 ggatcaattt tgacaaaaag cgctcgtttg ctttttccga cagttttgag cgttttaata
    11221 acgaaatcaa ggagttcaaa attggcgtag tccatgattg gcccacgtgg gatataaatc
    11281 atagtgaaac caagaggaag ttttctgatt aaacaagcag cagcagcaac ttgtacccca
    11341 ttttcataaa agctgatgcg ttcgtgtttc cagttatctt tgacttttcc ccactttgaa
    11401 ctttgaagta agccagcttg tggctgtgct aagacaaact gatcatgttc ttcaggagat
    11461 attccgattt tatatgtata cattagttta atacccactt gcgaatagca tgtgccacac
    11521 cactgtcatt gttggatttg gtgatgtatt tggctatttt tttcaattca ggaaccccat
    11581 tttccatgac aacagggttg gcaacgactt ctaacatagc acgatcattt tcagcatccc
    11641 cgatggccat ggtttgtgac atatctagcc cgagtttttt agctaagtgt ttgatggcat
    11701 tacccttgct gacggttttt ggcatgaact ctaaataaaa aggggttgac ttgacgatgg
    11761 tgtacttatc aaagaaatgt tgaggaattt gcttgatggc cgcgtccaaa aggtcaggtt
    11821 catcaatcat catcattttg atgatttctt tattggtcat ttcttcggga gtgcgataga
    11881 aaataggcat gtttaccaaa gtcgattcat gaactgtgta ttttccaata ttccgattgg
    11941 cagtgtaaat accttctttg gtaatggcat gcatgtgaac tcctaatttt cggctcaaaa
    12001 attccgtttc cagataatcg tcgtaagtca tcaattcttt aacaatttct tcgccggtct
    12061 cggcatcttg caccaagcca ccattaaaag tgataacgtg gtttcctttg tggttgagtt
    12121 ctaattgttc gagtaatgaa atcactccgg caataggtct gccagtagca atcaccacat
    12181 gaaccccttg ggctttagct tcttggacag cttgaaaaac atcatctgta attcgacggt
    12241 catcagtgag taatgtgcca tcaatatcga cagcaaccag tttgatagac atggcatcct
    12301 ccttgttttt ttgtggttta tcttaaaaat gttctccctc ctatcttact aaaaataggt
    12361 gcttttgtca tgggatggga aaggaaactt aaggaaaaac gagagaaaac gttttagttt
    12421 agctcaatcg cctctgtagt aactaaaaag attgaagaaa gtactctttc ttcaatctta
    12481 gactggagac aaacccagtt tgatgctcaa aaagcatgaa ctgctctgct gatttgacaa
    12541 ctgatttctt atttctgcgt gtgacgtgag ccaaaacagc tgctttttgc tgtggcaaaa
    12601 gtggtgtcaa tactggcagt gacgttacgc ggggtttttg agaccctagg ctcaaaaata
    12661 aagcatagaa ttccaaagga agtcgctgcc ataagcatca cctaagaaaa gtatcaaaaa
    12721 agactttttc tgcaatctta aagggcttta ctgactaaag tgaaaatgcc cattggaaat
    12781 ataactcata aaagtttcct tgctaggagc aaagaggtca tcgagctcta acatttcctt
    12841 tggaaaataa aagcgacggt ctccgtaggt tgtccctgtt aatgctttga caataggaga
    12901 taactgagat aattcagcaa ggctcccgtc tttttgtatc atttcaatct gagttcttgg
    12961 attttcgagc tctggtcgat aaatatcata aggcaggtcg aagttgatat ggataccggt
    13021 gtaataatct ggatcaaagc caactgattc gaccaattgg cgcaagcgtt ctaactctcc
    13081 ttgggaatct tggtcaaagg taacagactt cagaattttt cgattaataa aacgactggc
    13141 caaatctgat aagatatggt cttcgcttgc catccagact tgaaagtaag tattcatgac
    13201 tccgtcatct agggctatat aatctgctaa attagccttc ttttcaaaga aggggatgag
    13261 tccaggagct gttttttgga aataagcctg ttgctcagga tataagtgtt gggctctttt
    13321 gaggagattt tgtaagatga gctcaacagc acggctggcg ggatgaaaat agacctgcat
    13381 gtacatttga aaacgactga caatatagtc ctcgacagca tgcataccac tatgttcaaa
    13441 gacaatgcca tcttcaacag gtcgaatcac acgtaggatg cgcattaaat caaactgacc
    13501 gtaattagca gcagaaaaat aagaatctct taaaaggtaa tccatacggt cgcagtcaat
    13561 ctggctggaa atcagttgca caacttgctt gttaggataa gtatgattaa tcacgctggc
    13621 aactttgtct ggaaaatcag gagcatgacg caccaaaatg gcattgattt ctgtctcagg
    13681 attggtaatt atctcctgag taaaggcctc gtgatccgta tgaaaaagag cctcaaaggt
    13741 atgagaatag gctccatgac caatgtcatg taagagggca gccgtcatag tgaccagatt
    13801 ttcatcttta ttccagatat cagcgtattt ctcttcaaaa atagctgtca cccgacgggc
    13861 aatttcgtaa acacctaggc agtgagaaaa acggctatgt tctgcgccgt ggaaggtgaa
    13921 agctgttgta gggacttgtt tgatgcgtcg taagcgttgg aattctttgg tattgataag
    13981 gtcataaatt aatggattat caatgtggat atagttgtga acagggtcac gaaatacttt
    14041 ttcattcata atttttatta tatcaaaaat tgataaaata aggagaaatt gatagaataa
    14101 acagacgagc ttagaataga aagaagagtt atgaaattac agttaaccaa ccatattcgc
    14161 tttggagatg agacagagat tattcaagaa attcatgatt gtgagtggcg agaaaaagga
    14221 ggctatcagt acctcatcta tcaaaacact gacaaggaaa aggttgtcat caagtataat
    14281 gagacagaac tgaccatgag ccgtttttcc aaccctcagt caatcatgaa attttttgcg
    14341 ggcaagaagg tcctgattgc tctacctacg ccgatggggg ttcaacaatt tttgacagat
    14401 accagtcatt accacttaga ttgttcttgt caaaaattgg accttcatta tcatttgctt
    14461 caagctcaaa cagaaatgct atttgcaagc tatcatcttg agctgagttg ggattaacta
    14521 aaaagatagc agtaaatcat ctgattaggg attattcttg ttttttagtc aggtttttac
    14581 tataatggtt attatatcaa gggagtagca gacggctagc cgtgattgta tcgtcaatac
    14641 ggaatttcgg tttccggtac aatcttaaac agcgagactt gtttaagaaa aataaacagg
    14701 tctttttatt tgaacaacta aaataaaaag accaaggagg tactaatttg tctaaagaac
    14761 aaagacatga agcattttac acgcaaagtg aagagaccgt actggctcaa ttagagacca
    14821 gtcgcgaagg tcttacgtct gcccaagcaa aagagcgctt agcagagtat ggtcgtaatg
    14881 agcttgatga aggcgaaaaa cgaagtttat ttatgaaatt ccttgatcaa tttaaggatt
    14941 tgatgattat tattttgatt gtggcagccc ttctttcagt tcttacagag gggatggaag
    15001 gtttgacaga cgccattatt atcttggctg ttgttatcct aaatgctgct tttggtgttt
    15061 accaagaagg acaagctgaa gctgctattg aagccttgaa atcaatgtca agtccactgg
    15121 ctcgtattcg ccgtgatggg catgtgactg agatagactc taaagaattg gtccctggag
    15181 atattgtctt gctagaagcg ggagatgttg tccctgctga tctgcgtctt ttggaagcta
    15241 actccttaaa aatcgaagaa gcagcgctta ctggagaatc tgtaccggtt gaaaaagact
    15301 tgtcaacggc tgtttcagaa gatgccggta ttggtgatcg cgtcaatatg ggatatcaaa
    15361 actcaaatgt gacatatggt cgtgggattg gggttatcac taacactggt atgtacaccg
    15421 aggttgggca tattgctggt atgcttgcta atgctgatga gacagataca ccattgaagc
    15481 aaaaccttga caacctttct aagattttga cttatgcgat ccttgtgatt gcagcggtga
    15541 cttttgctgt tggagtcttc ttgcgtggtc aacacccgct tgaaggcttg atgacttcag
    15601 tagcgcttgc cgttgcagct attccagagg gacttcctgc gattgttact gttgtgcttt
    15661 ctcttggaac tcaagtactt gctaaacgta acgccattat ccgtaaatta ccagctgttg
    15721 aaacgctagg atcaactgaa atcattgctt ctgataaaac gggtaccttg acaatgaatc
    15781 aaatgaccgt tgaaaaagtt tataccaacg gggcactcca aagttcatca gctgatattg
    15841 cttttgacaa tacgacactt cgtgtaatga actttgctaa tgatactaaa gttgatcctt
    15901 cagggaagtt aattggtgac ccaacagaaa cagctttggt acagtttggg ttagaccaca
    15961 attttgacgt acgtgaggct atggtggcag aaccgcgcgt ggcagaatta ccatttgatt
    16021 ctgaccgtaa gttgatgtca accattcata aacaagctga tggcaaatat ttcatcgctg
    16081 ttaaaggtgc gccagaccaa ttgttgaagc gtgtcacaca gattgaagaa aatggacaaa
    16141 ttcgtcctat tacggatgct gataaaaaaa ccattcttga taccaataag agtcttgcca
    16201 aacaagctct tcgtgtcttg atgatggctt acaaatattc tgatgctctt ccaacactgg
    16261 aaacagaaat tgttgaggct aatcttgtct tctctggttt ggtaggtatg attgaccctg
    16321 aacgtcctga agcagcacag gctgttaaag tagctaagga agctggcatt cgtccaatca
    16381 tgattactgg tgaccaccaa gatacagcaa aagctattgc gaaacgtctt ggtattatcg
    16441 aagaagatgg cgttgatcat gtctttacag gtgctgaact caacgaatta tcagatgaag
    16501 agttccaaaa agtctttaaa caatactccg tgtatgcccg tgtatctcct gagcataaag
    16561 ttcgtatcgt taaggcttgg caaaatgaag gcaaagttgt tgccatgact ggtgatgggg
    16621 ttaacgatgc accatctctt aaaacggcag atattggtat tggtatggga attacaggta
    16681 cagaggtttc taagggagct tctgacatgg ttcttgccga tgataacttt gcaaccatta
    16741 tcgttgcggt tgaagaagga cgtaaggtct tctcaaatat tcaaaaaaca attcaatatt
    16801 tactttctgc taacatggca gaagtcttta ccatcttcct tgcaaccttg tttggttggg
    16861 atgtgcttca accagttcac ttgctttgga ttaacttggt aactgatacc ctaccagcta
    16921 ttgctcttgg tgttgaacct gctgagcctg gtgtgatgaa gcacaaacct cgtggacgta
    16981 agtcaagctt ctttgatggt ggggtgaagg aagccattct ttaccaaggt gccttccaaa
    17041 ccatgctggt tcttggggtt tatggttttg ccttgatgtt cccagaacac acaagctacc
    17101 atgatgtcca tgcagatgct ttgaccatgg cttatgtgac cctcggtttg attcagttgg
    17161 tacatgccta caacgtgaaa tctgtttacc aatccatctt tactgttgga ttgttcaaaa
    17221 acaaattgtt caactattct attccagtgg cctttgtagc attaatggca acagttgttg
    17281 ttcctggatt taatcaattc tttcatgtga cacacttgac gatcacacaa tggttagtgg
    17341 ttattatcgg aagtctcttg atggttgttc ttgttgaatt ggtgaaagct gttcaacgat
    17401 cacttggtca agatgaaaaa gcaatttaat agacgctaaa aggtttgaga caattgtctc
    17461 aaaccttttt ttataatcgt tacaatgata aggactattg gtatgcctga cattaaaaag
    17521 ttgattcttg ccaattgact tgacagtcaa aaatttgttg tttggcttct tgactgtgac
    17581 cttcaatatc atcgattaaa atcttagtag cctgttcgcc ttcttcatag gcgggttgga
    17641 taatagttgt tagtgttggt gaagaaaatt ttgtccactc aatgttatca aatcctacta
    17701 gtccaatctc tggtatatta aatttaagag acttcatagc tgtaaatact tttggaagag
    17761 cccaacaatt ggggacaaaa accaaactct ttttagtcag tgatccttgc aaaaattgag
    17821 caattgcctc tgaagaagtc tgattttcat caataatcat ttcttgatga gtaagatgat
    17881 tagcttctaa cacatcaatg aagcccgaag cgcgttcaat acgagtgcta agtaaattgg
    17941 ggttacccgt gatcatgata aaatgttcat aacctttatc gatacattgt tgaatggtat
    18001 cataaacagc atcataatta ttagttttga cccagtttgt gcgatgttcg taaagttggc
    18061 tatcaaaaaa gaccactttt ttcttcttaa tatcgataat gcgagaatac ttcctgaaat
    18121 tagaggtagg ctgaatgata aagccatcca ctccgaggtt cagcatcttt tcaatgagtt
    18181 catcttcgcg agaagggtcg tagttgctgt ttccgatgat aatttggtaa ccaaattcct
    18241 gggctttgct ttcaattccc ttaacaattt gattggaaaa actattggta atatcaccaa
    18301 taaccacgcc aatgagttta gtagatttgg cgtttagact tctggcagca atgcttggtt
    18361 tataattggt agcttcaatc gtgcttttaa tgcggttttt agtttcttca gacatcttgt
    18421 caaacctacc atttaagtag aaagaaactg ttgtttttga agttttcgct aattcagcaa
    18481 tatctttgat ggttactttg cgctgcattg catacactcc tttaaaatag taatggttag
    18541 tcatattata acataaggac tcgtaaaaga tttagtgttt caatcgaata atctcattcg
    18601 tgatatggtt gataacaacc acctttcctc tgattttatg actatttagg agaactagtt
    18661 tttctccttt aattaagtcc tcttggagaa cacagatact gtagtcaaac tgctttcctt
    18721 ttaaatgcca ggaaagggcg gtctcaattg ggttgcgttt gcctgtttga agtggtgtta
    18781 agggagtaac tttggtatcg tcagggacta acagggtact ggtgtaaccc ttgtctttaa
    18841 agggttttcg tttgatgagt ttgtgactag tcaggtattg gttgtatttt tttgacaaaa
    18901 tcgtttcttc gatagtgaaa gggcagtcac tgattagtct gagatcacta aggtgatctg
    18961 tctttacttc taagtgatta tcaagaataa attgactgac aagacagtgg ttgccttgag
    19021 cctgtatcgt atcaatgata agcaaaattc ctggtggtaa gatgagaatt tgtcggtcat
    19081 gttggtagtt gttcctatca gagaattgcg tctggtagct accttcaata aagtaaacgt
    19141 gtccattttg tcgaaggtga caataattgg atttggggta agaaaggtaa gcccaggagc
    19201 tatcaatctg ctcaggtaat tgttcttcta agaaggcggt agaatgatgg ctagcgcttt
    19261 ttagggcata gcgtaatggt tcttctttgt aagtgtatcg cccagcatca cagaaaagtg
    19321 gttgtccttt ataatagaga cagatactat tttggtcgct atgggtatgg gaactaccga
    19381 tgggcccatt tttgaaaaaa agataataat tttcttgatt gatggtaatg tgcccggaat
    19441 gttcaaagtg atgcgcaaaa gttggtaagg tttggacggg taactgttca aaagtgtgga
    19501 cacctttttc tcctagaagg agaagactat cgatatcaag tgtgggaaaa gcagcagctt
    19561 ttaagtgtgg ttcttcaagg atagtggctg ctagtgttag aatatctctg gtatcggtaa
    19621 agtcactgtc tcctaagggg atctgtttgt ggtcagggcc agtcattttg aggagataat
    19681 cactcatggc aagcaaagta ggtctaagct gtggaagata atcagggact agagcagtta
    19741 attccagaag ggctttgagt acttccacat gatacatggt tgattgttca aattgactgc
    19801 cgtcttcgag aatttggagt gcgatttgtt gcgtcaattc ttttctagcg aaagctgttg
    19861 ctgcagcaat atcaaggtca gaaccaaagt aggcatcagc taataaaatc gcagtggttt
    19921 gcaagattcc ccaattgctg agactgtatt tatcaaggta gttggcatgg agaaagtgaa
    19981 gttgtttttc cagggaagct aggatgagcc tttcctcttg cttggttaag gcgtcaaaaa
    20041 gattaaggta aatcaaacat ttgacccaag caaaacaacg gatgccagta tctaaggttc
    20101 tagtagctaa ccccttaggg tctaaaggaa tagctgattc aatccaattg aggatgaaac
    20161 ttttggcttt taggagatac cgttcatctc tttcaacaag gtagacgagg attaatgttt
    20221 ggagataggt ctgtcgattt aacataaaat tccactcagg atcatctgtg acagcctttt
    20281 gccaagtaat gggatctaag tggtaaggga tgtggcaggg ctccatatcc caattatctt
    20341 caaataaaaa ggtattggtt aagagtaggt cagctatcct ttttcgatca gcatagctgt
    20401 cagcctgata gtctagcagg taattcctgc aaaagtctgg attgactgtt tctttaaagc
    20461 gtgtgaaggc aagagacata ggacatttcc tttccaaaag aaaagagacc tcatcatgtg
    20521 cttaggaact atttccctat gctcataaca ggtctctgtg aaccattaag ctaaaatacc
    20581 taaccagcta ccgataatac cgataagaac agtgaggaga accaatttgt aggttgtcca
    20641 ttttttgttt ttaataaggt aatacatgag taaggtaaag agagctggta aaagtgcagg
    20701 agcaatttta tcaagcattc cttgaatagt cacaaatttt tgtgctgtat tggccgcatc
    20761 caccttgcca gccgcaaaag taatgggaac agttatttta acagaagtag cagctaatcc
    20821 agcgataacg gtaacaccga caatatttgc catgcgcgac acaaccgcca tttgttcact
    20881 taatttatca ataaagcttg tgccgacttt atagccatag agaccagaac cgattttaat
    20941 agcagttagg ataatattca tggctaggaa gaagaaaatt ggacctaaaa ctaaaccatc
    21001 actagctaag gaagctgcaa tcgttgaaaa gagtggcgcc aagcaaaatt gtgataagga
    21061 gtcaccgata ccagctaaag gccccataag tgccattttg atgtttcggg tttcttcttc
    21121 aggacgatca ttttctaaca tgaccaagtg cagactggtg atgaaaggaa agaagtgagg
    21181 gttggtattg taaaactcac agttatcttc taaagcttga tacaagccct ttttatcact
    21241 gccaaaatgt tttttcaagg caggatagat gacattggcg tatccgatac cttggtaatt
    21301 actgtaatta aacccatttt gtaggaagaa agctctcaga gctgttttga ggtaatcttt
    21361 cttggttaat ttattagatc cagtcatctt gttggcctcc ttggacagtt gttgcatcga
    21421 cttgtttagg tttgttgtaa aattcattca aggcgaaaat gataccaata atggcgatac
    21481 cgatggttgg aatttggagg taggccgcac aaacataacc aatcagtaca aaaggaatca
    21541 actccttctt ggccataaca gataagatca tggcaaatcc gatagcaggt aacattttac
    21601 cagcgacagt caatccattg agcaagacag gtgggatata atccactaag tgaaggagag
    21661 tatccattga caaggcacct aataaaccaa ggcctaatcc aaggatagca aaagaccaaa
    21721 tggtcccatt agcagcgaat ttgaagcctc taatattgcc tttttgcaat tgttttttag
    21781 cggtttcagg agccccggca aaagcggtat aggcgaatgt ctgaagaaat tggatggcaa
    21841 ctgcgattgg tgttgataag gctagggccg cttctggggt gactttacca gcactggtaa
    21901 tagccatcaa ggtaccaaag ataccagggc cgataggatt aggtggaacg gtaccaccgg
    21961 cacccactcc aaatcccata taagctaatt cggagatagc tcccatgcta agtgcagttg
    22021 gcaagtcacc taagatcatc cctacaccaa aagacagaat aatacaacgg ttggtgtaga
    22081 tgccaagtaa cattccgctg aaacaaaagg ctgtccaaag accaattaaa agtgcctgta
    22141 acaaattgat atccatatca atctccttta ttcattaaat ataatctaag atgtcaacgt
    22201 cagaggcgct attgccagct ggagttgttt tggtgttaaa aaccacttgg tggtcatggg
    22261 ctaagcaacg aatagcagac ttgtctgttt ctcccagcga aataaactgg gtaatcgcaa
    22321 ccttatcatc agttttatga atattaccga tattgatttc tgtgatggga acaccccctt
    22381 caactaggcg tttggcatct tgcaaatctt tgatcacgat gaagatattt tgagcaggac
    22441 ttgctttatg aatgatgtca atcacttttt gaatggagaa aaaacgaatg gcaatactgg
    22501 atggaataac tgttttcatg agggattgtt gaatcttatc ttcagaaacc gcatcgttag
    22561 cgacgataac ggtgttgcag ttgaggaatt tgacccataa ttgcccctgt ccgtgaatca
    22621 aacgctcatc aactcgcgtc atgataatgt ttggttgtgt cataaaatct cctttttaaa
    22681 tgtaggtatc ggtgtttgtt accagtaagg gttccagtct ttgtagaaac gaagcagagc
    22741 ttcaagatag taatagtctc cccagatatt tccctcgtca accccttttc cagagtgcca
    22801 agaatagact ccgtgaagca gtagaggagc accaggcttg agatctttgt tagcataatc
    22861 cttaatcaag gctcttagca tgctgtgcat ggcagcttca tatgtttttt tatcaggatc
    22921 atgatctggt aaggttttta acatttcatg aataccacac acagcaatgg cggttgctga
    22981 actatcacga gactgctcgc taccatctcc aaaaattaaa tcccagtagg acacctggtc
    23041 tttaggaaga cggttcaaga aataatgggt catgcccttg aagagttgaa tgagttcagg
    23101 ttcttttagg aaacgatagg tcaaaggaat accataaatg ccccaagctt gccctctggc
    23161 ccaagcagaa tcatcgctat aaccttgtcg ggtgacccct ttaacaggat cgcctgtttc
    23221 tggatcaaag tagaaggtgt ggtaagcaga ggcgtcatct cggatgacat gattggctga
    23281 ggcgtagaaa tgattgatcg ccatgtcacg gtaacggttg tctccagttt cttggctagc
    23341 aaaaaagagt aattggatgt ttaggagaca atcaatgatt aaacggtaat cttctttttt
    23401 acccagttct ccccaggcct gaataaagcc gcctttgtct tgatagcgtt ggactaattt
    23461 gtcggctgct ttcaaagcag cttctctagc ctcaggtgtt tttaaaagtt tccactcagc
    23521 catgcaagaa ggggtgtaaa gaaagcccaa atcatggtga tctagctcaa tgtctcttgt
    23581 tactcgatct aggaaagaaa ggtcatttgc ttgagccaga gctttaatgg catcatcccc
    23641 actgtattcg taagctaacc aaaggcaacc tgtccaaaag gcattggtcc attccgtgtt
    23701 gtccataatg gcgtattggt tatctttggt agctggcgtt ggaaaatctt ctttgaagta
    23761 gtccatgtta agccgaactt gtttgagggc taagtcaagg gcctgagtaa tgtcttcttg
    23821 gcttaggaaa tcttctttgg taaatcgttc aggctgcttg ataggttcaa gagcaatggt
    23881 ttttaaagat cgtgtcatta aatgcctcct aactcatcgt ctgtcgtacc gtcttcttgc
    23941 tgagaaagag ttttccagtc aacaatgcct tctttagaac atgttataag tcctgatact
    24001 aaatcgtcaa aagaagctgc tgtttgtctt gcaaaactag cttcaatcag catggctaag
    24061 ttaaggccag aaagaacatt acacgtcgtg tttggaagag attccattaa ggttgcagcg
    24121 actttaaaag gggtacctcc tagaaggtca caaagaacta aggtttcctc ttctgggatt
    24181 aaagcacgag ataattggtc ctgcacatca gcggcggtca tctcagcagt aaaatcaatt
    24241 gcagttacct tctcttgtgg tcctgcaatt aactctaggg atgagacaat cccacttgca
    24301 aagtgtccat gtcccataac aataatagca atcatgataa aactcctttt ggtttaccgg
    24361 tttacttaaa aatattgtag cgctttcaaa attctttgtc aatacttttt taaaagattt
    24421 ttgaaaaaga aaaagtgagc agttgtgcta aaaaagaatc aaaaatggtc ttttttgtca
    24481 ctatttaatg tagaaaagtc ttaatagcta ttaagtatag gacaagacta aacaagaatg
    24541 acagtttgga taagagcact cttttaaatt ttgaaccgtt ttcattaaaa tgattgacaa
    24601 aactagttta ctttgttata gtcttggtaa acaggtttac ttaatttaat aacaaaaagg
    24661 agaatcctat ggaaaatatg ttttcgttac aaggtaagat tgccttgatt accggagcat
    24721 cttacggtat tggttttgaa attgccaaag cctatgctca agcgggtgca actattgtgt
    24781 ttaatgacat caaacaagag ttagttgata aggggttggc tgcctatcga gagttaggga
    24841 tagaagcgca tggctatgtt tgtgacgtga ctgatgaagc tggtatccaa cagatggtta
    24901 gtcaaattga agatgaagta ggtgttattg atattctggt caacaatgca ggtattatta
    24961 ggcgtacgcc gatgcttgaa atggccgcag aagattttcg tcaagttatt gatattgatt
    25021 taaatgctcc ttttattgtg tcaaaagctg tattaccatc aatgattgca aagggacatg
    25081 gtaaaattat aaatatctgt tctatgatga gcgaattggg gcgtgaaaca gttagtgctt
    25141 acgcggcggc taaaggtggc ttgaaaatgt taaccaaaaa tatagcctct gagtttggag
    25201 aagccaacat tcaatgtaat gggattggtc ctggctacat tgcgacgccc caaacagctc
    25261 cgttgagaga gcgacaagca gatggtagtc gtcatccttt tgatcaattt atcattgcta
    25321 aaacaccagc agcacgttgg gggacaacag aagacttagc tggtccagct gtttttctag
    25381 ctagcgatgc cagtaatttt gtcaacggcc atattcttta tgtcgacggt ggcattttag
    25441 cttatattgg aaaacaacct taatcacaca ctagaaagag attttatatg aaaattgcat
    25501 taattaatga aaatagccaa gcggctaaaa atggtatcat ttacgatgcc cttaccacag
    25561 tgacagataa acacggctac caagtcttta actatggtat gtatggcaca gaaggtgaaa
    25621 gccagttgac ctatgttcaa aatggactct tagcttctat tttattgacc actaaggcgg
    25681 ctgattttgt ggtgactggt tgtgggacag gtgttggagc tatgttggcc ttgaacagct
    25741 tcccaggtgt tacctgtggt tttgcgagtg agccaacaga agcttatctc ttttctcaaa
    25801 tcaatggtgg taatgccttg tccattcctt ttgccaaagg ttttggttgg ggagcagagt
    25861 tgaatttgac cttaatattt gaacgcctct ttgcagaacc aacgggtggt ggttacccta
    25921 aagagcgagc tattcctgaa cagcggaatg cacgtatttt aagtgatctg aaaaaaatta
    25981 cttacagaga tttgttggca attgtcaaag acatcgacca agatttcctc aaagaaacga
    26041 tttctggcgc tcattttaaa gagtacttct ttgccaatgc ggagccgtca gaattagtta
    26101 cttatttgaa atcagtactt gaacagtaat tccattttga cgaggaaagg agatcacatg
    26161 tctaagttat tattggttgg tgaaccgctg atacgcgtta gtcccaatca gtttcagcct
    26221 ttgaccaatg cctgcgacgc tcagcttttt ttcggcggtt cagaagttaa tattgcaaga
    26281 actctaggcg gttttggctt agaagcaagg ctatttacgg ccctaccaga taatcctgtt
    26341 ggtcacgctt ttcatcagtt tttgaagcaa agcggtgtgg atatgacctt gacggcttgg
    26401 cagggcaacc gtgttgggct gtattacctt gaaaatggct ttggttgtcg ttctagtcag
    26461 gtttattatg accgctgtgg ctctagcttt tcggccttag ataaggatag tcttgatcta
    26521 gctgccattt ttgaaggcat tagtcacttt cattttagtg ggatcagttt ggcgctgggc
    26581 aaaaaaactc aggacctgat tgaggtactt gtgagagaag ctaagaaaag ggatatttgt
    26641 gtttcttttg atcttaactt tagatctagt atgattgcgg tagctgatgc taaacgactc
    26701 ttttctcact ttgctcaata cgcggatatt atttttggca tggaaccttt gctgttagac
    26761 agtgacgatt ttgacatgtt tgataggaat aaggcagatg ctacgatgat tagagaacgt
    26821 ctggcaggac tttatcagcg ctatcagtta caagctattt accatacgga gcgttcaaat
    26881 gatgcccaag gcagtaatcg tttcaaggct tatgcctatg atgggcagtt ttacgaatcc
    26941 tgtgaagtga cgaccccagt cttgcaacgg gttggaagtg gagatgcttt tgtggcgggt
    27001 ttactttatc agttgttaga aggtaacgaa aagcagtgca accttgattt tgctgtggca
    27061 acagctagcc taaaatgtac agtagctgaa gatcagctct atcacagcgt ccaacaagta
    27121 gaagcagtct tacataatca acgagatgtc cagaggtgat gatatgggaa aaatagaaat
    27181 cttaaccaaa cttaaggcta atcggcttgt cctggttgta cgaggagagt ctagtgagga
    27241 agctttagct tgcagcctgg ccagtattga aggtggcatt aagacaattg aagtcaccta
    27301 tactaacccc tttgctagtg aggttatcgg tcaattagct gaacgcttca aagaagatcc
    27361 tgaggtattg ataggtgctg ggacagtttt ggatgatgtc actgcccgcc aagctatttt
    27421 agcaggagca cagtttattg ttggtcctaa tttcaatcga gcagtggctt tgatttgtca
    27481 tcgttatagc ataccttatt taccaggttg tatgacggtt aatgaagtgg ttacagcatt
    27541 agaatcaggg gttgatatgg tcaaaatttt tcctggttct actgtaggga tatcctttat
    27601 tcgggcaatc aaatctcctt tgccacaagt agaggttatg gttacaggcg gagtttcttc
    27661 agataatctc aaagactggc tagctgctgg agtagatgtt ctaggtatag gaggcgagtt
    27721 taatcagtta gcgagccaaa aacaatataa cctaatcact aagaaagccg ctcattatat
    27781 caaaagtttg cgacaataat ctaaaaaacg tttttacctt ggctttagtg ctagtaaaaa
    27841 cgttttttta tcattcattc aattaatatg cttctgctta tgtttttcca gatagtatag
    27901 atataagagc agctaattta acaagatgag cctgtcgttt gatatatagg atataaactt
    27961 tttatgatca aacaaaagta ataccttttg aattcgttag tattgacctg atctaaagtg
    28021 atatcactta gaatgaacta gctgtacagc ttttacagca acttatgcta aaatagaaaa
    28081 aaaggagaaa tgttgatgat taaaggaatt atttttgata tggacggtgt tttatttgat
    28141 acagaacctt tttatctgag gcgacgagaa gattttttta agacaaaggg aattcccatt
    28201 gatcatttga actctaaaga ttttattggg ggcaatctcc aagaattatg gaaagagttg
    28261 ttaggtaaaa atagggatga tgctatcgtt aaggcaatta caactgacta tgacgcttac
    28321 aaacaagcgc ataagcctcc ttatcaaaaa ctgttgatta cagaagtgaa ctcttgtctt
    28381 gaacagttga aaaaacaagg tattaaactg gctgtggcat caaactcgaa gcgtcaggat
    28441 gttttgttgg cgttggagac aacgcaaata aaagattatt ttgaaataat cctagcgcgt
    28501 gaagatgttt ctagaggcaa accttatcca gatatctata ataaagcagt acaaaaacta
    28561 ggattacaaa aaaaacaact gcttgtagta gaagacagcc aaaaaggcat tgctgccgcc
    28621 aaagcagcca atctgacagt ttttgccatt accgactacc gatatggcat tgatcagagt
    28681 caagctgatc acaagataga tcatttagga caactgtgtg tgaaaatcgg ttgttttgga
    28741 tcgtgaagta acgcaactaa ctgatcattg atgatacttc aagacactta agaatacgtc
    28801 taggactttc tacagaccaa taacaagaat acgtttatgt gtttttactg ttttttagct
    28861 acctatttac aatatgacac tgaaaagagt actatgttta agttattatc aaaaaaaccg
    28921 tcgcataaga tcacctagaa aaggattatg atttttgtga tttggatgcg atcgttagtc
    28981 gttgaccatc tttatgtggc aggagatatg tttaaccgtg gtcattattt ggatttgttt
    29041 ttagattggc tagtgagtaa atatagaagg atcataatac tgctttgaca aaggcagtat
    29101 ctgagtccat gagttgcacg ggtaatgtga ctcggttttg gttaggtata ataatatttg
    29161 gaagtgttat gctgcttgtc ttcgtaggtc cattgcttat agtcagactt actttagagc
    29221 tgagctgact gtctagacaa gacgtgatgg agatgtgatt tctgaccaag tagaggtaac
    29281 cagaaaaggg acttttacga tggaattgaa tttacttgtt gcattcttgt gcatgttaag
    29341 agagaaaacc cagataaatc aggaagtaaa atggttatgt ttgattagaa ttgtccttct
    29401 ttttccttga agtcttaact tattttgatt atgatagtag tatgactatt aaggcagaaa
    29461 ttaaggcact cgccaaagaa attggtatct ctaaaattgg ttttacgacg gcagataact
    29521 ttgattattt ggaaaagtca ttgcgtgctt ctgtggaaga ggggcgcaat tcaggatttg
    29581 aacataaagt catagaggat cgtatctccc ctgaaaggct tttagaatcg gctaaaacga
    29641 ttatttcaat tggcgttgct tatcctcaca aacttcctca gcaacctcaa aaaacacctt
    29701 ataaacgtgg caaaattaca cctagttcgt gggggtttga ttatcattat gtggtcggcg
    29761 aaaagttaga aagactacca aaaggcattg aagagctgtg tcgagatttt cctttgcaac
    29821 aaaaagcaat ggtcgatact ggagctttag ttgatactgc agttgcccaa agagcaggta
    29881 ttggttttat aggaaaaaat ggtctagtta tttctaaaga atatggctct tatatgtttt
    29941 tgggagaatt aattaccaat ttagagatcg agccagacaa tcctgtcgat tatgattgtg
    30001 gtgactgtcg tcgttgtcta gatgcctgtc caacttcttg tttaattggt gatggctcaa
    30061 tgaatgccaa gcgttgtcta tcatttcaaa cccaagataa gggaatgatg gacatagagt
    30121 ttcgaaaaaa gattaaaaca gttatctatg gttgtgatat ttgccaaatt tgctgtcctt
    30181 ataacaaggg tataaacaat tcaccagcta cagagattga tcctgagttg gcccaaccag
    30241 aattaatacc atttttgagt ttatcaaatg gaaaatttaa agaaaaattt ggtatgattg
    30301 ctggaagttg gcgaggtaaa aatattttac agcgtaatgc cattattgcg ctagcaaatg
    30361 ctcatgataa aactgcagtg gtcaaattaa tagagattat tgataaaaat aataacccta
    30421 ttcatactgc aacagctata tgggcattgg gagaaattgt caaaaaacca aacgatgaga
    30481 tactggcgtt tatgagtcat ttaaccttaa aagatgaaga tagccgaaaa gagttggaat
    30541 taatccgtca taaatggcaa ttttaagcct tttatggtat ttttaagaac cttatgataa
    30601 aataaaacag attaacaaag attggagaaa tctcatggaa gtggctgaaa ttcgccaaaa
    30661 aatagtagaa aataaagaga agttgactag cttcaggagg tctctttgac ttagatcgtt
    30721 tggaagagga gattgctctt cttgaaaatc acatgactga gccagacttt tggaatgaca
    30781 atattgcagc gcaaaagaca tctcaagaac taaatgagtt aaaaggtaag tatgatactt
    30841 tccataatat gcaagaatta tctgacgaaa cagaactctt acttgagatg cttgacgaag
    30901 atgattcttt gaaagaagaa ttagaagaaa atctaatgca gctagataag ataatgggtg
    30961 cttatgaaat gacgcttctc ttatctgaac cctatgacca caataatgct atcttagaaa
    31021 tccatcctgg ttcaggagga actgaagcgc aagattgggg agatttactc ttacgaatgt
    31081 atacccgttt tggcaatgct aatggtttca aagtagaagt attggattat caagcaggag
    31141 atgaagctgg tattaaatcg gttaccctct cttttgaagg ccccaatgct tatggtttgt
    31201 tgaaatcaga aatgggagtt catcgcctcg ttcgtatatc accttttgat tcggctaaac
    31261 gtcgtcatac ctcatttgct tcagttgaag tgatgccaga gttagatgat acgattgaag
    31321 tagaagtacg tgatgatgac attaaaatgg atactttccg ttccggagga gctggtggtc
    31381 agaatgtcaa taaagtatca acaggtgttc gtttgacgca tattccaact ggaattgtgg
    31441 tatcgtctac cgttgaccgt actcaatatg ggaaccgcga tcgcgctatg aagatgttgc
    31501 aggctaagct atatcagtta gaacaagaaa agaaagcaca agaagtagat gctctcaagg
    31561 gtgataaaaa agaaatcact tggggaagtc agattcgttc ttatgttttc accccttata
    31621 cgatggtgaa ggatcatcgt actaactttg agcttgctca ggtagataag gttatggatg
    31681 gagaaatcaa tggctttatt gatgcctacc ttaagtggcg cattgaagac taaaaataat
    31741 aaaggagaaa catggcacta atagaaatgt ctggtgttac taaaaaatac cgccgctcaa
    31801 cgaccgccct cagagacgtc aatgtttctg ttaaccaagg tgagtttgtt tatctcgtag
    31861 gcccatcagg tgctggtaaa tcaactttta tcaaactcct ttaccgtgaa gaacaactga
    31921 caactggtaa gctatatgtg ggtgaattca atttaactaa actaaaagca cgtgatgttc
    31981 cgattcttcg tcgtcacatc ggagtagttt ttcaagatta caaactgcta ccaagaaaaa
    32041 cagtctttga aaatgtagct tacgccatgg aagttattgg tgaaaagcgc cgccacatta
    32101 aaaaacgcgt gccagaggta ctcgatttag ttggcttgaa acataagatg cgttcttttc
    32161 caagtcagct atcaggaggg gagcagcaac gtgtggccat tgcgcgtgcg attgttaata
    32221 atcctaaatt attgattgca gatgaaccga cagggaattt agatcctgag atttcatggg
    32281 aaattatgca gttacttgaa cgtattaatg ttcagggaac aactatctta atggcgacac
    32341 acaacagtca tattgtgaat acattccgtc atcgtgttgt tgctattgaa gatggtcgca
    32401 tagtacgtga tgaagaaaaa ggagattatg gttacgatga ttagatactt tttccgtcat
    32461 atttgggaat ccattaaaaa tcttaaacgc aacttttgga tgacatttgc ttcagttagt
    32521 atggtggctg ttacattgac tttagttggt gtttttgcgg cgacattgtt gaatatacag
    32581 cgtgttgctt cgggtgttga aaataatgtc catatcaata cttacttaca agttgattca
    32641 actgatgctg caaaagttat tcaaaatact gccggtgaac ctgttaataa cgataactac
    32701 cacagtgttt acgacaaaat tgctcagata aaaggtgtca aaaagattac attttctagc
    32761 aaggatgaac aattgaaaaa attgcaagaa accttaggtg atgtttggaa tatgtatgac
    32821 caagacacta atccgctcca agatatctat cttattgaga cccagacgcc taaacaagtt
    32881 aaggcgatca ctaaaaagat cagaacgatt gaaggcgtag aagccgcaga ttatggaggg
    32941 attaactccg ataaactatt taagttttca acattaattc aaacttgggg gctgatcgga
    33001 acagcaatgc tattatttgt agctgtcttt ctcatttcaa acactattcg tatgactatt
    33061 atgtctcgta aacgcgacat tgaaattatg cggttagttg gtgctaaaaa ttcttatatt
    33121 cgagggcctt tcttttttga aggggcttgg gttggcttgt taggagctgt tttaccatct
    33181 cttctgattt attatggata tgatcttgtt tataagcatt ttgcacaaga attacaacgt
    33241 aataatctct cgatgtatcc gcttgatcct tatgtatatt acctgattgg tgctttgttt
    33301 gtcataggta ttatgattgg ttcgcttggt tcagtgcttt ctatgagacg ttatttaaaa
    33361 ttctaaaaaa agcgctgctg acgaaacgta gcaaccctca aaagttggac ctcttatgtt
    33421 attccaagga cctcgttttg tattgcacag gactggtcct tttcattttg ttttgattca
    33481 tttgtttatt tgtaataggc aatacagttt aaaatagcag tttctaaggt ttcaagagaa
    33541 gaaaagcacc ccaaaagtta gatgtttgat gtatctaact tttggggtgt cattcaaaat
    33601 ttagtggctc ttttttagta aaatactatg atttcagttt taggataacc tcaaacagta
    33661 tctaaaatag ctatgtcaat gaaaaaaggg gttagcattt ttttcgtgac aaatggtagt
    33721 agaaggacca tgcccaggat aaactcggta atgattaggt aaggtgaata gttcttggcg
    33781 aataccagta atgaggtcct caaagttact ggtaggtaag tcagtacgac cgatagtttc
    33841 acgaaataga gcatcgccag taacgactaa ttcatctgag tggaaaacaa atgagactcc
    33901 tccccaagaa tgaccaggtg ttggtaaaac tgtgaattca aaaccattta gttgataggg
    33961 ttgctttaat ttaaaaaagt tctctgccgg tcttgctata acagtaatga tatcatcatg
    34021 acggcctaag ccagataaat tatcatctgg ggaagatagc caagcggctt ctttttctga
    34081 aacataaaca ggtggatgat caaaagcatc tctgaccaaa tctaaactaa aaatatgatc
    34141 ataatgagta tgcgttaaga ggatagccac taaaggtttt tcaaaggatt taattttagc
    34201 aatgatttct tggccgttac ttcctggatc aatgaggata acagcttgat cattaacgag
    34261 gtaataagta ttttcaccag caatgtggtt tattgtttta tagattttca taaggatagt
    34321 gtaccaaaaa atcaaggctt tgttaaaaaa agagtggcgg aaaataaatg gcaattagtt
    34381 tcagaaaata tgagatctca cagcaatttc ttgacaccgt tttcataaag gtgtatcata
    34441 aaagtaatca ataagccaag cctaaagctg aacttagttt aagaacactg actttttgag
    34501 agcaacctaa tcggttgact aaaaaatatg aggtggaaga tatgtcaaaa gttgctattg
    34561 ttactggtgc tggtcaagga attggatttg ctattgcgaa acgtcttcat gcagacggct
    34621 ttaaaatagg cattttagac tataatgaag agactgctca ggctgcggtt gataaactat
    34681 cacctgagga tactgttgca gttgtagcag atgtttcaaa acgtgaccaa gtttttgatg
    34741 ctttccaaaa agttgtagat acttttggtg atttgaatgt tgttgctaac aatgcaggtg
    34801 ttgccccaac aacccctctt gacacgatta ctgaagagca gtttgaaaag gcttttgcaa
    34861 tcaatgtcgg aggaacgatt tggggaagcc aagcagctca aaaacatttt agagaattag
    34921 gtcatggcgg aaaaattata aatgcaacgt cacaagcagg atgtgaaggg aatcctaatt
    34981 tgactgttta cggtggtaca aaatttgcag ttcgtggtat tacacagact ttggcaaagg
    35041 atttggcatc agaaggaatc acagtcaatg cttacgcacc aggtattgtt aaaacaccta
    35101 tgatgtttga tattgcccat gaagttggta aaaatgcagg caaagatgat gaatggggta
    35161 tggagcaatt tgcaaaagat atcactttga aacgcttgtc tgaaccagaa gatgttgcta
    35221 atgcagtagg cttcttagcg ggagatgatt caaattatat cactggacaa acaatagttg
    35281 tcgatggtgg tatggtattc cattaaaaat gattaatact gacactgtga gtttcactca
    35341 cagtgttttt tatatttctt aaaaaattat cctatcttgg ttattggagt gatggcacct
    35401 ttgagatata gtcatgtttt gttttataga tatagcgtgc tataatagac ttactatgac
    35461 ccagaaaaaa cttagaaaat atgcagtagt ggacttggaa gctactggag caggtcccaa
    35521 tgcttctatt attcaggttg ggattgttat tatccaagga aataaaatta ttgatagtta
    35581 tgaaacagat gttaatcctc atgaatcttt agatgagcat attgttcatt tgacaggtat
    35641 tacggataag cagttggcta aagctccgga ttttggtcaa gtggcgcatc acatttatca
    35701 attgattgaa gattgtattt ttgttgccca caatgtaaag ttcgatgcaa atttattggc
    35761 agaagctctt tttttggaag gatatgagtt aacaatacca cgtgttgata ctgttgaatt
    35821 agcccaacta tttttccctc gctttgaaaa gtataacctt ggtcacctat ctaggcagct
    35881 caatattgat ttggcagaag ctcatactgc tattgcagat gcaagagcta cagctatact
    35941 gtttctaaga cttttacaaa aaattgagag ccttccaatt gagtgcttag aaagcttatt
    36001 agtctattca gatagcctgc tatttgaaac agcaatggtc attcaagaag gattagccaa
    36061 agccaaacct tatgatccca acaaatacat taaaatcaga cagattctct taccaaaggg
    36121 ctcaaaagct ctcaagcctt atcaaatatc aaaaagcttc cctattaata tggcactatt
    36181 aggtctggaa gaaaggccta aacagactca atttgctcag ttaattgacg aagattacca
    36241 tcagggagta gctagtttta ttgaagctca gacaggtatt ggaaaaacct acggctacct
    36301 gctacccctt ttggcaaaag aagatcaaaa ccaaatcatt gtcagtgtgc ccaccaaact
    36361 tcttcaagac caattaatgg ctggtgaagt agctgctatt caagaacaat ttcacatcgc
    36421 ctgccatagt ttaaaagggc ccgccaatta cctaaagcta gatagctttg cagatagttt
    36481 ggaccaaaat gaccagaacc gtttggtgaa tcgttataaa atgcaattat tggtttggct
    36541 cttagaaact aagacaggag accttgacga aatcaaacaa aagcagcgct ttgcagctta
    36601 ttttgagcag cttaagcacg atggagacat taagcagtct tctgaatttt acgattacga
    36661 tttttggaga gttagttatg aaaaagccaa aacagcccgt ctcctgatta ccaaccatgc
    36721 ttatttttta caccgtgttc aagatgacaa ggactttgct agaaacaagg tcttggtctt
    36781 tgatgaggcc caaaagctga tgctccaatt agatcaatta tcacgtcatc agcttaacct
    36841 gacggttttt ttacaaacaa tacaggccaa gttaagcaac cctttacctc ttttagaaaa
    36901 acgcttattg gaaagcttgt cgtttgaact gggacaagtg tcaagtgatt actatcaaaa
    36961 taaagagcac cagcttgctc atgattggtc tcgtatagct ggctacgcca aagaattaac
    37021 aggagcagat tatcaagagt tacaagcctt ttttgccacc tcagatggtg actactggct
    37081 tagtagcgaa aagcaagagg agaagcgagt gacttatcta aacagtgcta gtaaggcatt
    37141 tattcatttc caacagctct taccagaaac ggtgaaaact tattttgttt ctgccacttt
    37201 aaccatcagc tcagaagtaa ccttggcaga cctattaggt tttgaagagt atctctatca
    37261 tgtcattgaa aaggataaaa agcaagacca gttggtgctt gttgatcaag aggcgcctat
    37321 cgtgacagaa gtcagtgacc aaatctatgt ggaagcaatt gcaaaacgaa tcgaaagctt
    37381 gaagcaagag ggttatccta ttttagtgct ttttaattct aaaaaacact tgctgttggt
    37441 ttcagactat ctagaccaat ggcaggtgcc tcacttagcg caggaaaaga atggaacagc
    37501 ttacaatatt aaaaaacggt ttgatcaagg agagcaaact attttgcttg gtttaggttc
    37561 tttttgggaa ggagttgatt ttattcaagc ggatcgtatg attaccctta tcgcacgatt
    37621 gccttttgat aacccagagg atttctttgt taagaaaatg agtcattatc tattggaaaa
    37681 aggtaaaaat cctttcagag attacttctt gccaatgact attttgcgat taaaacaggc
    37741 tattggccgc acgatgcgtc gacaagatca aaagtcagtg gttattattt tggatcgtcg
    37801 tctccttaca aagtcctatg gacaagttat tttggaaggt ctcggtcagg aatttttgat
    37861 ttctcaacaa aattttcacg attgtctagt agaaacggac tgttttctga tataatggaa
    37921 aggatctatt atatcagaaa aatttttaat ggcgttaagc acaatcaact aacatttaaa
    37981 ttagtttgaa cttttattat gctcttttag acaactgttc aaatgttttc aaattgtttt
    38041 tttgataagg acaataaatg aacaaatttt tggttttagt aaacccaatt actgttcttt
    38101 tcattagtgt cagttgctat caaaacagct tgtcatagtt cgtgcgatca gtagcgagta
    38161 ttggtaaaac tgaaaccgta gattatgaaa aaatgatctg ttgatcatta attaatctga
    38221 agataagaag tcgataaaaa ggagatacga tgcccaaact atcaaagcga gttttagaaa
    38281 tgaaagagag tgttactctg gctgcaggtg ctagagctaa ggctttgaaa gcgcagggcc
    38341 gcgatgtact gaatttaact ttaggagaac cagatttttt tacacctaag cacattcaag
    38401 acaaggcgat tgaatctatt caaaatggta cggctagctt ttatacaaat gcttctgggc
    38461 ttccagaatt aaaagttgcg attgccacat acctgaaaaa tcagtatggg tatcacttgt
    38521 ctcctgatca gattgtggca ggaacaggtg ccaagttcat cctttatgcc ttttttatgg
    38581 ctgttttaaa tcctggtgac caagttctca ttccaacacc atattgggta tcttattctg
    38641 accaagtaaa aatggcagaa ggtcagccga tcttcgttca aggactagaa gaaaatcaat
    38701 tcaaggtaac tgttgaccag ctggaaagag caaggacaag taagactaaa gttgtcctta
    38761 tcaattctcc ttccaatcca acaggcatga tttatggtgc tgaggaatta agggccattg
    38821 gagaatgggc ggtgcacaac gatattctta ttctggcaga tgatatttac gggtccttag
    38881 tctataacgg caatcagttt gttcctattt caacactctc agaagcgatt cgtcgtcaaa
    38941 ccattacggt caatggcgtg gctaaaagtt atgccatgac aggctggcgg gttggttttg
    39001 cagcaggtga accagagatc atttcggcaa tgagtaagat catcgggcag actacctcta
    39061 acctgacaac cgtttcacaa tatgctgcta tcgaggcttt ctgtggtagt cagtcatcac
    39121 ttgaagagat gcgattagca tttgaagagc gccttaatat cacttatcca ttgttgtgtc
    39181 aggtccctgg gtttgaggtt gttaaaccac aaggagcttt ttacttcttt ccaaatgtta
    39241 agaaagccat ggaaatgaca ggtttttccg atgtgacaag ctttgccaat gctattttag
    39301 aggaagtcgg attagctgtt gtgagtggag caggctttgg cgcaccggaa aatgttcgtc
    39361 tgagttatgc tacagatatc gaaaccctta aagaagctgt tcgtagattg catgtcttta
    39421 tggaaagtaa tgaaattaat taaataaaaa tagagagaaa cttatgtcaa aaaaacttat
    39481 ttcaattgtt gatgttaaag attatgttgg tcaagaagtt actattggtg cttgggttgc
    39541 taacaaatca ggtaaaggta agattgcgtt tgtacagttg cgcgatggtt ctgctttttt
    39601 ccaaggtgtt gcttttaaac caaacttcat tgaaaaatat ggtgaagaat caggtcttga
    39661 aaaatttgac gttattaaac gtctcaacca agaaacatct gtttatgtaa cagggattgt
    39721 taaagaggat gagcgttcta aatttggcta tgagcttgat attactaacc ttgaaatcat
    39781 tggagagtca catgaatatc ctataactcc taaagagcat gggacagact tcttaatgga
    39841 caaccgtcat ctttggttgc gttctcgtaa acaaatggct gttatgcaaa ttcgtaacgc
    39901 tattatttat gcaacttatg aattctttga caaaaatggt tttatcaaat ttgatagccc
    39961 aattttatca gaaaatgcag cagaagattc aacagagtta ttcgaaacag actattttgg
    40021 gaaaccagca tttcttagcc aatctggtca attatacctt gaagctggag caatggctct
    40081 aggccgagtt ttcgactttg gtccagtctt tcgtgctgaa aaatctaaaa cacgtcgcca
    40141 tttaacagaa ttttggatga tggatgctga gtattctttc ttgtcacatg aggaatcact
    40201 tgaccttcaa gaagcttatg ttaaagcatt gatccaaggc gttctagatc gtgcgcctca
    40261 agcacttgat attttagaac gtgatgttga ggctctcaaa cgttatatca cagagccatt
    40321 caagcgtgtt tcttatgatg atgctattac acttcttcaa gagcatgaag cagatgaaga
    40381 tacagattat gaacatttag agcatggtga tgactttggt tccccacatg aaacttggat
    40441 ttctaattac tttggagtac cgacatttgt agtgaattac ccagcaagct ttaaagcatt
    40501 ttatatgaaa ccagttcctg gaaatccaga acgcgttctt tgtgctgatc ttttagctcc
    40561 agaaggttat ggagagatca ttggcggctc aatgcgtgaa gacaactacg atgctcttgt
    40621 ggctaaaatg gatgaactag gtatggataa atcagaatat gacttttacc ttgaccttcg
    40681 taaatacggc tctgttcctc atggcggttt tggtataggt attgaacgta tggtaacttt
    40741 tgttgctggc accaaacata ttcgcgaagc tattccattc ccacgtatgt tacatcggat
    40801 tagaccctaa taatacaaaa agttcatgtc atctatgaac tttttgtatt ggtaagaagt
    40861 gagtgtgtta taaaaacatc aatatgtcct aaaggagaga taagaaatag tagagtttga
    40921 acctacatcc tttgtgaaga taaattttgg aagtttagta gatcagttag cagataagac
    40981 aatatagcct tgctcaaggg atattttata gacaagtatt tggactacga ttatcaaata
    41041 gacactctca tttgatacta aaaaggtctc gtctattaat ataataggag agctacggga
    41101 gttattatta aaattagctg atttttacag ttcaaaatgt gttaccactt tttcacttct
    41161 tagctttctt atgtatgtgg tataatgaag gtggacggtt cgatagagaa agggaaattg
    41221 taaatgtcag acaaacacat taatttagtt attgtgacag gaatgagcgg cgctggaaaa
    41281 acagttgcca ttcagtcttt cgaggatcta ggctacttta ccattgataa tatgccccca
    41341 gccttggttc caaaattttt agaattaatt gaacaaacca atgaaaatcg tagggtggct
    41401 ttggttgtcg atatgagaag tcgtttgttt ttcaaggaaa ttaattctac cttagatagt
    41461 attgaaagca atcctagcat tgattttcgg attctttttt tggatgcaac ggatggagaa
    41521 ttggtgtcac gctataaaga aaccagacgg agccatcctt tggctgcgga cggtcgtgtg
    41581 cttgatggta ttcgattgga aagagaactc ctatctcctt tgaaaagcat gagccaacat
    41641 gtggtggata caacaaaatt gacccctaga caattgcgta aaaccatttc agaccagttt
    41701 tctggaggat ctaatcaagc ctctttccgt attgaagtga tgagctttgg gttcaaatat
    41761 ggtcttcctt tggatgcgga tttggttttt gatgtgcgtt ttctacccaa tccttattat
    41821 caggtagagc ttcgtgaaaa aacaggacta gataaggacg tttttaatta tgtgatgtct
    41881 cacccagaat cagaggtgtt ttacaagcat ttgttaaacc ttattgtccc tatcttaccg
    41941 gcttaccaaa aagaagggaa gtctgtcttg acggtggcta ttggctgcac aggaggccaa
    42001 caccgcagcg ttgcctttgc ccattgcttg gcagaaagtc tggcaacaga ttggtcggtt
    42061 aatgaaagcc atcgtgatca aaatcgtcgt aaggaaacgg tgaatcgttc atgaaaaatc
    42121 ctaaaatgac tgttataggt gggggtactg gcatctccat tatcctaaaa agccttcgta
    42181 atgaagcagt tgatattact gctgtggtca ctgttgcaga tgatggtggt tcctcaggag
    42241 aacttcgtaa tgccatgcaa ttagccccgc caggagactt acggaatgtc ttgttagcga
    42301 tgagtgacat gccaaaattt tatgagcggg ttttccaata ccgttttaac gagagtgatg
    42361 gagccttggc tggtcaccct ctaggcaatt tcattattgc tggtatctct gaaatgcaag
    42421 gctcaaccta caatgccatt caaattttaa ccaaattttt ccatattaca ggtaaaattt
    42481 acccctctag cgagcaggcc ttgacccttc atgctgtttt taaagatggg catgaagtag
    42541 caggagaaag ttctattgcc aaataccaag gcatgattga ccatgtctat gtgaccaaca
    42601 cctacaacga ccaaaagcct caggccagtc gtaaggtggt tgaggctatt ctagaaagtg
    42661 acatgattgt cttgggacca ggctcactgt ttacctctat tttacctaat ttggtcattc
    42721 cagaaattaa agaagctttg cgccagacta aagcagaagt ggtgtatatt tgtaatatca
    42781 tgacccagta tggtgaaaca gaacaatttt cagatgcaga ccatgtggct gttttaaatc
    42841 agcacttagg aagagatttg attgatacgg ttttggtaaa tgtggctaag gtgccgcagg
    42901 cttacatgaa ttctaacaaa tttgatgaat acctcgttca ggttgatcac gactttgctg
    42961 gcctttgcag ggctgctaag cgtgtgattt cgtcttattt tttacggttg gagaatggcg
    43021 gagcttttca cgatggtaac ttagtggtgg aagaattaat gaatttagtg aggatagtca
    43081 agcaatgagt tttacaacca aggtcaaaga ggaattaatt cacttgtcca caggtgacaa
    43141 caatgaattg gccgccatta tcaaattatc aggcagcttg ggcttagctc accaaagcct
    43201 tcatttgtcc attaccactg aaaatgctaa aattgcccgc tacatttatt cttttattga
    43261 agatgcctat gttatcgtgc cagaaatcag gtatcatcaa aagacgaacc tgcgcaaaaa
    43321 ccgtgtttac accgtctatg ttgagcaagg tgtggaaacc attttagccg atttgaaatt
    43381 agcggactcc ttttttggtc tggaaacagg catcgaacct caggttttat cagacgataa
    43441 tgctggccgt tcttatctta aaggggcttt tttagcggca ggtagcatca gagatcctga
    43501 gtcaggcaag tatcagttag aaatctattc agtttatctt gatcacgcgc aggatttagc
    43561 tcaactcatg caaaaattta tgctagatgc caaaaccatt gagcataaaa gcggtgcagt
    43621 tacttatttg caaaaggcag aagatatcat ggacttttta attataattg gtgccatgtc
    43681 ctgcaaagaa gactttgaag ccatcaaatt acttcgagaa gctcgaaatg atattaaccg
    43741 tgccaataat gcagaaacag ctaatattgc caaaactatc agtgctagca tgaaaactat
    43801 taataatatt attaaaatca tggacacaat tggtttagaa agtttaccga ttgaattgca
    43861 acaggtagcc cagcttcggg ttaagcatcc agactattcc attcaacaag ttgctgatgc
    43921 ccttgagttc ccaatcacca agagcggggt caaccatcgc ttgcgtaaaa tcaataaaat
    43981 tgcagatgac ttatagaata tttttatcgt atgagccttt tttcatacga tttttttgtc
    44041 taaaaggaat tttcaattgc cttttgaagt gtctgatgtt ctggaatttg aaacactctt
    44101 aattaaaaca a
//
LOCUS       DATTYN010000015        41156 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.15, whole genome shotgun sequence.
ACCESSION   DATTYN010000015 DATTYN010000000
VERSION     DATTYN010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41156
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.15"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            212..1282
                     /locus_tag="VB649_000995"
     CDS             212..1282
                     /locus_tag="VB649_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669954.1"
                     /translation="MMMLRDVKVKTSSLLVGCAATLLVSLSSTVAADSVHSSDRRFGV
                     GYKEETTSQFSSDQPSQVVLYRGEANTVRFTYTNQMYLMKDIRIALDGSGKSLTAQTV
                     PGMGHVYEGFQTSARGIFTMSGVPESTVLVANPNVQTKYTRYFKVIDDMHNTMYKGTV
                     FLVQPQAWKYTMKSVDQLPVDDLNHIGVAGIERMTTLIKNAGALLTTGGSGALPDNIK
                     VSINPKGRQATITYGAGSTDIIPPAVLWKKGSVKEPTEADQSVGTPTPGIPGKFKRDQ
                     SLNEHEAMVNVEPLSHVVKDNIKVIDEKSTGRFEPFRPNQDEKEKPASDVKVRPAEVG
                     SWLEPATALPSVEMSAEDRLKS"
     gene            1375..1773
                     /locus_tag="VB649_000996"
     CDS             1375..1773
                     /locus_tag="VB649_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEP1669955.1"
                     /translation="MHRLPNRLIPEEDNNKLSRVAKEVVTEPRLNNPFLLPKKVLSLE
                     DDAAILNHLEEDRNVNKLFLEPVAAEAKREINFHPSDQQVTAKVKESSDFHQKQHQTG
                     ITYGDDTLADLTHHLLHSDGVIPSLNDKSA"
     gene            complement(2121..2390)
                     /gene="stcA"
                     /locus_tag="VB649_000997"
     CDS             complement(2121..2390)
                     /gene="stcA"
                     /locus_tag="VB649_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system protein StcA"
                     /protein_id="HEP1669956.1"
                     /translation="MTKKQFYLILAISILCFILAVSPKPPIPKHTIERKRTAMTIGHS
                     KQNPHKKEALKHKKNKNKALFLPSGDSAIKSVISMTVRLLLDDQS"
     gene            complement(3304..3372)
                     /gene="shp2"
                     /locus_tag="VB649_000998"
     CDS             complement(3304..3372)
                     /gene="shp2"
                     /locus_tag="VB649_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP2"
                     /protein_id="HEP1669957.1"
                     /translation="MKKVNKALLFTLIMDILIIVGG"
     gene            3461..4327
                     /gene="rgg2"
                     /locus_tag="VB649_000999"
     CDS             3461..4327
                     /gene="rgg2"
                     /locus_tag="VB649_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg2"
                     /protein_id="HEP1669958.1"
                     /translation="MEKELGKTLRRLRKGKQVSISFLADEYLSKSQISRFERGESEIT
                     CSRLLNLLDKLNITIDEFVSAHSKTHTHFFTLLSQARKCYAEKNVVKLTKLLKDYAHK
                     DYERTMIKAILFSIDSSIAPSQEELTRLTDYLFKVEQWGYYEIILLGNCSRFMNYNTL
                     FLLTKEMVASFAYSEQNKTNKTLVTQLSINCLIISIDHSCFEHSRYLINKIDLLLRDE
                     LNFYEKTVFLYVHGYYKLKQEEMSGEEDMRQALQIFKYLGEDSLYYSYKEHYRQIVLG
                     GKGDEDWSEADL"
     gene            4499..5326
                     /gene="mutM"
                     /locus_tag="VB649_001000"
     CDS             4499..5326
                     /gene="mutM"
                     /locus_tag="VB649_001000"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEP1669959.1"
                     /translation="MPELPEVETVRRGLETLVLGQEIVAVTLKVPKMVKTDLETFALT
                     LPGQIIQSVGRRGKYLLIDLGQLVLVSHLRMEGKYLLFPDEVPDNKHFHVFFELKNGS
                     TLVYQDVRKFGTFDLIAKSQLSAFFAKRKLGPEPKKETFKLKTFEAALLSSQKPIKPH
                     LLDQTLVAGLGNIYVDEVLWAAKVHPETASSRLNKAEIKRLHDETIRILALGIEKGGS
                     TVRTYRNALGADGTMQDYLQVYGQTGKPCPRCGQAIVKLKVGGRGTHICPKCQKKRP"
     gene            5323..5916
                     /locus_tag="VB649_001001"
     CDS             5323..5916
                     /locus_tag="VB649_001001"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEP1669960.1"
                     /translation="MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRL
                     YEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLT
                     QSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQL
                     PIEEKKPYASLVIDNSGDIAALIKQVQSALLSLANPR"
     gene            6106..7608
                     /locus_tag="VB649_001002"
     CDS             6106..7608
                     /locus_tag="VB649_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HEP1669961.1"
                     /translation="MTTMTIAKGNQPIALQLGMLNRHGLIAGATGTGKTVTLKVLAEQ
                     LSLAGVPVFLADIKGDLSNLTKAGEVTDKLAARLATIGVSDYQPQAFPVRMWDVFGQN
                     GQPLRTTISEMGPMMLSRLLNLNDTQTGVLNIVFKIADEKGWLLIDLKDLQAILKEVG
                     DHASDYSSHYGNVTKQSVGAIQRSLLTLEQEGAEQFFGEPALEVADLMQLDVASGYGA
                     INILSATKLFQSPTLYTTFLLWLLSELYELLPEVGDLDKPKMVFFFDEAHLLFKDAPK
                     VFLEKVEQIVRLIRSKGVGIFFVTQNPLDLPETVLAQLGNRIQHALRAYTPKEQKAVR
                     VAADTFRQNPDLDVARVITELEVGEALISVLNDKGQPSIVERAYIMPPKSSFAVLSDI
                     ESQQLVQSSPFASKYSQSIDRESAYEKLAAKVLEDNRLAQEAIATAQREKEAKEAIKA
                     QAATKKANRRSVGRPRKTVVEKATDAFISTTVRTIGRELVRGLLGSLRKR"
     gene            7730..8923
                     /locus_tag="VB649_001003"
     CDS             7730..8923
                     /locus_tag="VB649_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEP1669962.1"
                     /translation="MNWRQNLKVAWLGNFFTGASFSLVMPFMALYVENLGTPKELVEY
                     YAGLAVAVTALASALFAPVWGKLADRYGRKPMMLRASFVMTFTMGGLAIIPNVFWLLI
                     LRLLTGVFAGYVPNATALIASQAPKEESGYALGTLATGVTAGALIGPLLGGILAELLG
                     IRQVFLLVGVILFLCFLMTAVYVKEEFKPIRRFEMIPTKVILKQVKSPQIMLGLFVTS
                     MIIQISAQSVAPILSLYIRHLGQTHNLMFTSGLVVSAMGFSSLFSSSYLGKLGDRFGN
                     HRLLLAALCYSFIMYFSSALAQTSFQLGVLRFAYGFGVGALMPSINSLLTKLTPKEGI
                     SRVFAYNQMFSNLGQVIGPFIGSNVAVVLGYRSVFYVTSLIVFVNLIWSLIIFRKYIK
                     VKDIV"
     gene            8920..9066
                     /gene="rpmG"
                     /locus_tag="VB649_001004"
     CDS             8920..9066
                     /gene="rpmG"
                     /locus_tag="VB649_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP1669963.1"
                     /translation="MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTL
                     HVET"
     gene            9112..9348
                     /gene="secG"
                     /locus_tag="VB649_001005"
     CDS             9112..9348
                     /gene="secG"
                     /locus_tag="VB649_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEP1669964.1"
                     /translation="MYNLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLAIALVLAILSSK"
     gene            9442..11775
                     /gene="rnr"
                     /locus_tag="VB649_001006"
     CDS             9442..11775
                     /gene="rnr"
                     /locus_tag="VB649_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEP1669965.1"
                     /translation="MMKERIMTYLKEHGKSNVNDLAAALEMAGSKHFPSLIKTISKME
                     SQSLLRFSDDGSLALRKEREKKKEPTVQGVFRANKAGFGFLHVDENEDDMFIGRNDVG
                     YAIDGDTVEVVVKKPADRLKGTAAEAKVVAIVDRSLKTAVGTFILDDDKPKYAGYIRS
                     KNQKIQQKIYIKKEPVVLKGTEIIKVDIDKYPTRGHDYFVASVRDIVGHQGDVGIDVL
                     EVLESMDIVSEFPAEVLAEANAISEAPTAKDLIGRVDLRQETTITIDGADAKDLDDAI
                     HIKLLDNGNYELGVHIADVSYYVTEGSSLDKEAIARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPNVDRLTQSALMEINPQGYVVNYQICQSVIKTTYRMTYSTVNDMIAGDEEALQE
                     FASIADDVTLMVTLHRILETMRSKRGALNFDTQEAKVIVNDKGMPVDVVLRQRGIAER
                     MIESFMLAANECVAEHFAKAKLPFIYRIHEEPKVEKLQQFIDYASTFGIHIQGTANKI
                     SQEALQAFMAKVEGQPGAEVLNMLLLRSMQQARYSEHNHGHYGLAAEYYTHFTSPIRR
                     YPDLLVHRMVREYNQPSQEKRDHFAQIIPELATSSSQLERRAIDAERVVEAMKKAEYM
                     AEYVGEEFDGIVSSVVKFGFFVELPNTIEGLVHITSLPEYYHFNERTLSLQGEKSGKV
                     FKVGQPIRVKLVKADKETGDIDFEYLPSDFDVVEKIKISDKASRRDRRKSSKSSKGIK
                     KKEPKEVAKAKTKGKTKKGSKKPFYKEQAKKKSRKRS"
     gene            11778..12245
                     /gene="smpB"
                     /locus_tag="VB649_001007"
     CDS             11778..12245
                     /gene="smpB"
                     /locus_tag="VB649_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEP1669966.1"
                     /translation="MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLENELKGSG
                     MTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR"
     gene            12251..12970
                     /locus_tag="VB649_001008"
     CDS             12251..12970
                     /locus_tag="VB649_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminyl-peptide cyclotransferase"
                     /protein_id="HEP1669967.1"
                     /translation="MSIMITKGQVRLLRTYSYDSNLYTQGLEQLNNNHILLSAGRYGF
                     SKVGVYDLTQEIFSEKIAFPDTVFAEGLTVVEDYFWLLTYKEGVAYKFDKATCNCLGA
                     YPFEGDGWGLAYDKENQCLWMTSGNAFLQKRDPKDFALLDTVLVAIESVPISMLNELE
                     YVDGYLYANIWQTNTIVKLQPDSGKVVATYDISPLLKALNLDKSHYPDLNVLNGIAHL
                     DQQRFLITGKLYPLMLEVVLD"
     gene            complement(13088..13735)
                     /gene="pcp"
                     /locus_tag="VB649_001009"
     CDS             complement(13088..13735)
                     /gene="pcp"
                     /locus_tag="VB649_001009"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEP1669968.1"
                     /translation="MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVF
                     QKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAK
                     AGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH"
     gene            complement(13785..14711)
                     /locus_tag="VB649_001010"
     CDS             complement(13785..14711)
                     /locus_tag="VB649_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 family protein"
                     /protein_id="HEP1669969.1"
                     /translation="MANIANLVLETIYILIGLQLFHTAYCTFKDKTNPVYFGTALFWG
                     LLGVTFVGGAFLPNKVIGFIVIVLALLTLFKQVRIGTLPAFNEQKAEESAHRIGNWIF
                     LPVMLMAMISLLLALILPDFSKSAIGIAGILATIAILIITKQKPSALLAENNRMNQQV
                     STSGILPQLLGALGAIFAAAGVGDVIASLIREIVPADSRFFGVLAYVLGMVIFTMIMG
                     NAFAAFTVITTGIGVPFVFALGADPIIAGALAMTAGFCGTLLTPMAANFNALPVALME
                     IKDRNAVIKKQAPIALVLIITHIALMYLLAYY"
     gene            complement(14711..15394)
                     /locus_tag="VB649_001011"
     CDS             complement(14711..15394)
                     /locus_tag="VB649_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEP1669970.1"
                     /translation="MEWIKLIGIVIIVLGFILKFNAIATVVVAGLVTALVSGISFIDF
                     LDILGKEFTNQRLLTIFFITLPLIGLSETYGLKHRATQLIQRVQSLTVGRLLTLYLII
                     RELASLFSIRLGGHPQFVRPLIQPMGEAAAKANIGEELTDTEKDDIKAMAAANENFGN
                     FFAQNTFVGAGGVLLIAGTLEQLGYDGNQAKIAFSSILIAIISIIIVAIYNYLFEKKM
                     ERQHQKGDN"
     gene            complement(15605..16531)
                     /locus_tag="VB649_001012"
     CDS             complement(15605..16531)
                     /locus_tag="VB649_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP1669971.1"
                     /translation="MTLLSIIVPCFNEEANILPYFEEMHQLETSMTNQLAFEYIFIDD
                     GSKDNTLGILRELAARFPNVHYLSFSRHFGKEAGLLAGLKEAKGNYITVMDVDLQDPP
                     ELLPIMYAKLKEGYDIVGTRRQNRQGEPLIRSMCSNLFYGLIKHLSDTEMVNGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYRITYLSFENQKRKYGKSRWHFWELLRYSL
                     DGFINFSEMPLTIATWTGTFSFLISIFAILFIIIRKILFGDPVSGWASTVSIILFMGG
                     IQLFCMGIIGKYISKIFLETKKRPLYIIKEKH"
     gene            complement(16676..17053)
                     /locus_tag="VB649_001013"
     CDS             complement(16676..17053)
                     /locus_tag="VB649_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEP1669972.1"
                     /translation="MKALHTCIRVKDLDQSVAFYTSAFPFEENYRKDFPDSQFTLVYL
                     ALEGESYELELTYNYGHGDYDLGNGYGHIALGSEHFEADHKKHRQAGFPVTDIKELAD
                     KSARYYFIQDPDGYKIEVIDLNN"
     gene            complement(17064..17729)
                     /locus_tag="VB649_001014"
     CDS             complement(17064..17729)
                     /locus_tag="VB649_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEP1669973.1"
                     /translation="MDQTIHHQIQQALHFRTAVRVYKEEKISDEDLALILDAAWLSPS
                     SVGLEGWRFIVLDNKPIKEEIKPFAWGAQYQLETASHFILLIAEKHARYDSPAIKNSL
                     LRRGIKEGDGLNSRLKLYESFQKEDMDMADNPRALFDWTAKQTYIALGNMMMTAALLG
                     IDTCPIEGFHYDKVNHILAKHNVIDLEKEGIASMLSLGYRLRDPKHAQVRKPKEEVIS
                     VVK"
     gene            complement(17778..18863)
                     /locus_tag="VB649_001015"
     CDS             complement(17778..18863)
                     /locus_tag="VB649_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEP1669974.1"
                     /translation="MTKLDQIRLYLDQKGAELAIFSDPVTINYLTGFFCDPHERQLFL
                     FVYHDLAPVLFVPALEVARASQAISFPVFGYVDSENPWEKIKAVLPNTAAKTIYAEFD
                     HLNVNKFHGLQTIFSGQFNNLTPYVQGMRLIKSADEINKMMIAGQFADKAVQVGFDNI
                     SLDATETDVIAQIEFEMKKQGIHKMSFDTMVLTGNNAANPHGIPGTNNIENNALLLFD
                     LGVETLGYTSDMTRTVTVGQPDQFKIDIYNLCLEAQLAAIDFIKPGVTAAQVDAAARQ
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMAGNDLVLEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKNGFEVFTHTPKELLYFEG"
     gene            19037..20038
                     /gene="ccpA"
                     /locus_tag="VB649_001016"
     CDS             19037..20038
                     /gene="ccpA"
                     /locus_tag="VB649_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEP1669975.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
                     VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            20169..21167
                     /locus_tag="VB649_001017"
     CDS             20169..21167
                     /locus_tag="VB649_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEP1669976.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQHFTTNPRETY
                     DLVHLNTYGLKSWLLMIKAQKAGKKVIMHGHSTEEDFRNSFIFSNLLSPWFKKYLCHF
                     YNKADAIITPTLYSKSLIESYGVKSPIFAVSNGIDLEQYGADSKKEAAFRRYFDIKEG
                     EKVVMGAGLFFLRKGIDDFVKVAQAMPDIRFIWFGETNKWVIPAQVRQMVNGNHPKNL
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYYGWVDQ
                     SSAELATDIPGFIEALKKVFSGASNKVEAGYKVAQSRRLETVGHALVDVYKKVMEL"
     gene            21169..22503
                     /locus_tag="VB649_001018"
     CDS             21169..22503
                     /locus_tag="VB649_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEP1669977.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDRD
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKHYNLDIIHTQTEFSLGLLGK
                     MIGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISY
                     EKNIQAIINQMPAILAENAKIKLIIVGNGPYLQDLKHLAMQLEVDKHVTFTGMVPHDK
                     VALYYKACDFFISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTEKMFGTLYYAE
                     TDLTDAIIDAILKTPVMDKRLLAKKRYEISAQHFGKSIYTFYLDTLIARNSKEAQKLS
                     LYLNHSGKSSSLKLVQGAIHLPKRAAKVTAITSVKVVKAPIKLVHAIKDFLD"
     gene            22925..24868
                     /gene="thrS"
                     /locus_tag="VB649_001019"
     CDS             22925..24868
                     /gene="thrS"
                     /locus_tag="VB649_001019"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEP1669978.1"
                     /translation="MIKITFPDGAVREFESGVTTFDIAESISKSLAKKALAGKFNDQL
                     IDTTRAIEEDGSIEIVTPDHKDAYEVLRHSAAHLFAQAAKRLFPNLYLGVGPAIAEGF
                     YYDTDNAEGQISNEDLPRIEAEMQKIVTENYPCIREEVTKEEALELFKDDPYKVELIN
                     EHAGAGLTVYRQGEFVDLCRGPHVPSTGRIQVFHLLNVAGAYWRGNSDNNMMQRIYGT
                     AWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPDGATIRRTLE
                     RYITDKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPVMDMGDGEEFVLRPMNC
                     PHHIQVYKNHVRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHIFVTPEQ
                     IQEEFQRALQLIIDVYADFNLTDYRFRLSYRDPNDTHKYYDNDEMWENAQSMLKAALD
                     EMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFDLKYIGADGEE
                     HRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPHQITVIPISNEAHIDYAWEVAKT
                     LRDRGVRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMEDKSVNVRRYGSKATHTE
                     SVEEFVENILADIARKSRPDAQA"
     gene            25009..26001
                     /locus_tag="VB649_001020"
     CDS             25009..26001
                     /locus_tag="VB649_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP1669979.1"
                     /translation="MVMIEVSHLQKNFSKTIKEPGLKGALKSFVHPQREIFEVVKDLS
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGYCRINGKIPQDNRQDYVRDIGAV
                     FGQRTQLWWDLALQETYVVLKEIYDVPEKAFRKRMDFLNEVLDLNEFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIIMIDKGQEIFDGTVIQLKQSFGKMKSLSFELKPGQEQVVSQFMGLPDIT
                     VERHELSLDIQYDSSRYQTADIIQKTIADFAVRDLKMTDVDIEDIVRRFYRKEL"
     gene            26003..26821
                     /locus_tag="VB649_001021"
     CDS             26003..26821
                     /locus_tag="VB649_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEP1669980.1"
                     /translation="MWSFWKRYRPFLSAGIQELITYRVNFFLYRIGDVMGAFVAYYLW
                     KAVFDSSKQSLINGFTLSDMTFYIIMSFVTTLLTKSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFMEIGFRWIVLMSVGFPFLMVLSGIKVMAGLSILQVLASSCLYLVSLLLA
                     FLINFYFNICFGFSAFVFKNLWGSNLLKNALVAFMSGSLIPLAFFPKMVSIVLSFLPF
                     SSLVYTPVMIVIGKYSLSQIMVALSLQIFWLLVMVVLSQVIWKKVQYHLTIQGG"
     gene            26823..27608
                     /locus_tag="VB649_001022"
     CDS             26823..27608
                     /locus_tag="VB649_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1669981.1"
                     /translation="MAKLRRMHAIFIKQYLKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     SVLFQHIPSLEGWTFEQIAFIYGFSLIPKGIDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PISPLFHVLVETFQVDALGELLVGVILLVTTAGSIVWTLPKVLLFILVIPFATLIYTS
                     LKIATASISFWTKQSGAVIYIFYMFNDFSKYPMSIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLTGQHLLFNIGGLVVASLLVLALSLKLWKWGLDAYESAGS"
     gene            27809..27958
                     /locus_tag="VB649_001023"
     CDS             27809..27958
                     /locus_tag="VB649_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase"
                     /protein_id="HEP1669982.1"
                     /translation="MQLLDNVYGTLRSFAFMRPVKSSNDTSLADALQADTDMAFILVR
                     GINYQ"
     gene            28353..29501
                     /locus_tag="VB649_001024"
     CDS             28353..29501
                     /locus_tag="VB649_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEP1669983.1"
                     /translation="MTDVYIAAGLRTPIGLVGKQFAKEQPEILGAKLINALQNKYPVP
                     IDQVICGNTVGTGGNIGRLMTLYSHLGESVSALTVDMQCASAGAALSVGYAKIKAGMA
                     SNLLVGGIESSSLQPESVYASADWRQGAYKVAQFSPDSISPFAMIEGAERVAREYGFT
                     KEYLNHWTLRSHQKASYCQEQALLADLILDLPGASDQGIRPHLSSKVLSKVPPILGED
                     HVISAANACLTHDAAAFLQISSQPSAFKLIDVVEVAGDPQRSPLMVIKASQVLLEKHG
                     LGMADMTAIEWNEAFAVIDGLFETHYPDLLDRYNIFGGALAYGHPYGASAAIIILHLM
                     RALEIKNGRYGIAAIAAAGGQGFAVLLKYHKEFSHADKARILGKAMPK"
     gene            29458..30705
                     /locus_tag="VB649_001025"
     CDS             29458..30705
                     /locus_tag="VB649_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEP1669984.1"
                     /translation="MLTKLEYWAKQCPNKKAIVADQISLTYQELWQAVLIKDHTIKDS
                     VPYIISHSRYLNQLLSFLRGLKEGSCPIILHPNISGTFQQQIKHVDSELLKKADFAVL
                     SSGTTGKAKLFWRCLSTWTRLFDYQNKVFGMTGNSCLFLHGSFSFTGNLNLALAQLWA
                     GGCLVLSQKLSLKTWLSLWQAKKVSHLYLLPTYLNRLLPYLTKNNMTATHLLTSSQMI
                     SQELLRHYYKKFPQLEIVIFYGASELSFITWCNGRAAVKINGLVGQPFPDVSISFKDK
                     EIFVETPYSVEGMSQPYSVSDLGKMSPAGLILEGRQDDWVNQRGVKCHLPSLVELAHQ
                     APNVKEAHALKIGKGENETLILVLVLTKKDCLAPIKDFLALYLNSGQLPKYYLVIDCL
                     PLKDNGKINREVLLNKIPKQWLS"
     gene            30761..31795
                     /locus_tag="VB649_001026"
     CDS             30761..31795
                     /locus_tag="VB649_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEP1669985.1"
                     /translation="MCYNMVKKDEEKAMKQAILDRYQALKCYQNAGLSNQAFRAIAKE
                     PIIDNRLGSPTFWVIWPIEKENQSAKQLLTFLLDLVEMPFELSGQLHETQTLLTRFHP
                     SLLPDHMFWKELASLVDQAFPGKTLSQAGELEKRLHQFRYVISSQQAQSIRNHYKMIE
                     MTDAQALALFLRSKKGPCLWRQAPDYTLMDSARLHNKLRFEDNKVIFPSQEVSYNIKV
                     LLWFHTEFILDSTGFFLNEVDAEVVTEKGIVNGASFNYGTDGPRHWDLDVDPISRHDP
                     QFRRDTLKGFRTPKRVFRQWFRAQKDDFMFSYFNAKGLFAYHNKSSFARVKKSAKQFK
                     RQIHPIKGWF"
     gene            31957..32667
                     /locus_tag="VB649_001027"
     CDS             31957..32667
                     /locus_tag="VB649_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1669986.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVE
                     LTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRTVDVTVRRLREKIEDTPSR
                     PEYILTRRGVGYYMKSYD"
     gene            32660..34012
                     /gene="vicK"
                     /locus_tag="VB649_001028"
     CDS             32660..34012
                     /gene="vicK"
                     /locus_tag="VB649_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEP1669987.1"
                     /translation="MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMM
                     SHKIRDLINGRYTDIIDEKADVELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
                     VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVT
                     QLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKAR
                     SRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
                     "
     gene            34016..34825
                     /locus_tag="VB649_001029"
     CDS             34016..34825
                     /locus_tag="VB649_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP1669988.1"
                     /translation="MNESGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRKPEDLDAILITHEHSDHIKGVGVMARKYHLDVYANEKTWQLMDECNMLGKLDA
                     SQKHIFQRDKVLTFGDVDIESFGVSHDAIDPQFYRIMKDNKSFVMLTDTGYVSDRMTG
                     IIENADGYLIESNHDIEILRSGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGYNTKK
                     IYLGHLSKENNIKELAHMTMVNQLAMADLAVGTDFTVHDTSPDTACPLTDI"
     gene            35268..35960
                     /locus_tag="VB649_001030"
     CDS             35268..35960
                     /locus_tag="VB649_001030"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEP1669989.1"
                     /translation="MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNE
                     RLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKL
                     GKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKD
                     YKTCLQEFLQTKGDVVIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQD
                     AAKNALAQLSEV"
     gene            35961..39500
                     /gene="smc"
                     /locus_tag="VB649_001031"
     CDS             35961..39500
                     /gene="smc"
                     /locus_tag="VB649_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEP1669990.1"
                     /translation="MFLKEIELEGFKSFADKTKIEFDKGVTAVVGPNGSGKSNITESL
                     RWALGESSAKNLRGGKMPDVIFAGTQNRNPLNYAKVAVILDNSDHFIKTAKKEIRVER
                     HIYRNGDSDYLIDGRKVRLRDIHDLFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQIKLNQTQDNLDRLEDIIYELDTQLAPLEKQAKVAKQFLEL
                     DANRKQLQLDILVKDIDIAQERQTKDTEALAALQQDLASYYAKRQSMEEDYQKFKQKK
                     QVLSQESDQTQTTLLELTKLIADLEKQIELVKLESGQEAEKKAEAKKHLEQLQEQLDG
                     FQAEEKQRTEQLLHIDQQLCDVKKQLNELSNALERFSSDPDQLMETLREEFVLLMQKE
                     AALSNQLTALKAHLDKEKQARQHKAQEYQLLVTKLDQLNDESQKAQAHYKAQKEQVEM
                     LLQNYQEGDKRVQELERDYQLNQERLFDLLDQKKGKEARKASLESIQKSHSQFYAGVR
                     AVLQSQKKFGGIIGAVSEHLSFDSDYQTALEIALGANSQHIIVTDEAAAKRAIAYLKK
                     NRQGRATFLPLTTIKARSLSEHYHRQLATCEGYLGTAESLVRYDDSLSAIIQNLLSST
                     AIFETIDQANIAARLLGYKVRIVTLDGTELRPGGSFSGGANRQSNTTFIKPELEQISE
                     ELTRLVEQLKITEKEVASLQSDLIAKKEELTQLKLAGDQARLAEQRAQMAYQQLQEKQ
                     EDSKALLAALDQSQTTHSDESLLAEQARIEEALTAIAKKKNALTCDIDDIKENKDLIR
                     QKTQNIHQALSQARLQERDLLNEKKFEQANQSRLRTQLKQCQQNILKLESILNNNVSQ
                     DSIQRLPQWQKQLQDATEHKSGAQKRLVQLRFEIEDYEARLEETAEKITKESEKNDTF
                     IRRQTKLETHLEQVANRLRAYAKSLSEDFQMTLADAKEVTNSIDHLESAKEKLHHLQK
                     TIRALGPINSDAITQYEEVHERLTFLTSQKTDLTKAKNLLLETINSMDSEVKARFKVT
                     FEAIQKSFKETFTQMFGGGSADLVLTETDLLSAGIEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFAIIRVKTIPFVILDEVEAALDEANVKRFGDFLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGITMQESGVSKIVSVKLKEAQEMTN"
     gene            complement(39785..40636)
                     /gene="rgg3"
                     /locus_tag="VB649_001032"
     CDS             complement(39785..40636)
                     /gene="rgg3"
                     /locus_tag="VB649_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Regulator gene of glucosyltransferase 3; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg3"
                     /protein_id="HEP1669991.1"
                     /translation="MKSKLGATLRKVRKGKQISLCFVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTNSETFANLVQYIRKQYSSQNINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSSIIPSDDELLQLTDYLFKVEKWGYYEILLLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSRNKTNKRIVTQLAINCFILSINKEEFSNCSYLIDEIK
                     SLLDNELNFYEQTVFLYATGYFEFKRQLETGVEKMKQAIQVLDILNEDKLKLHYADHF
                     DKLVNKD"
     gene            40716..40787
                     /gene="shp3"
                     /locus_tag="VB649_001033"
     CDS             40716..40787
                     /gene="shp3"
                     /locus_tag="VB649_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEP1669992.1"
                     /translation="MKKISKFLPILILAMDIIIIVGG"
     gene            40856..>41156
                     /locus_tag="VB649_001034"
     CDS             40856..>41156
                     /locus_tag="VB649_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEP1669993.1"
                     /translation="MLVLYVSSKLIKRRRMKFMYSALLGNPVEHSISDELFEYLNHNI
                     GVLDEYKHKKILVDSVCLEDKIKHLINDPKCIGLNITLPYKREVMRYIDNLDRVAE"
BASE COUNT        12819 a         7203 c         8730 g        12404 t
ORIGIN      
        1 tagtttagtg taaccgattc aattaaagaa tagttcgtga caagaagata cctttgaagt
       61 ttcagaaaca atctgttttc catcctgcta tactcatctt tgccaaagct cgtcatttta
      121 tatgatttat atagaattac gagttttttg ttagtctaat atgagaaaat atagtatgac
      181 gaattcctaa ataaaaaata atgaaaggaa catgatgatg ttaagagatg ttaaagttaa
      241 aacgagcagt ttattagttg gttgtgcggc tactttacta gtcagtttga gtagtacagt
      301 tgcggcagat tcagtccatt cgtctgatag acgttttgga gttggctata aggaagaaac
      361 aacctctcag ttttcttcgg atcagccctc ccaagtggtt ttgtatcgag gtgaggctaa
      421 cacggttagg tttacctata ccaatcagat gtatctgatg aaagatattc gcattgcttt
      481 ggatggttct ggtaagtctt tgaccgctca gactgttcct ggtatgggtc atgtttatga
      541 gggctttcaa acttctgcta gagggatttt tacgatgtca ggagttcctg aaagcactgt
      601 tctcgttgct aaccctaatg tacaaaccaa atatacaagg tatttcaaag tcattgatga
      661 tatgcataac acaatgtata aaggaactgt ttttcttgtt caaccgcaag cttggaaata
      721 caccatgaaa tctgttgatc agttaccagt agatgacttg aaccatattg gcgttgctgg
      781 tattgaacga atgacaactc tcattaaaaa tgcgggtgcc cttttaacca caggaggtag
      841 tggagcctta ccggacaata ttaaagtatc tattaatcca aaagggaggc aggctacgat
      901 tacttatggg gctggctcta cggatattat tcctccagca gttttatgga aaaaaggctc
      961 cgtaaaagag cctactgaag ccgatcaatc tgtcgggaca ccgactcctg gtattcctgg
     1021 taaattcaaa cgagaccaga gccttaacga gcatgaagct atggtaaatg tcgaaccgct
     1081 gtctcatgta gtaaaagaca atataaaggt catagatgaa aaatcaacag ggcggtttga
     1141 gccttttaga cctaatcaag atgaaaagga gaagcctgcc agtgatgtta aggtaagacc
     1201 agcagaagtt ggtagctggc tagaaccagc gacagctctt cctagtgttg aaatgagcgc
     1261 tgaggacagg ttaaaaagtt agttaataat ttgccggttg ctttagacag gcaaacagga
     1321 aagggcttgg aggtttcttc tgaagtagct gtgagcgtct cacagccgga agaattgcat
     1381 cgattgccta accgtttgat acctgaggaa gacaataata aactatcacg agtagccaag
     1441 gaagtcgtta ctgagccaag gctaaataac ccctttttgt tacccaagaa ggttctttcg
     1501 ttagaagatg atgctgctat ccttaatcat ttggaggaag accgtaatgt caataagttg
     1561 ttcctcgagc cagttgcggc tgaagccaag agagaaatta attttcatcc aagtgaccag
     1621 caggtgactg ctaaagttaa ggagtcatct gattttcatc agaaacagca ccaaacaggg
     1681 attacttatg gagatgatac tctggcagat ctgacgcatc atttgcttca ttcagatggt
     1741 gttattccta gtctaaatga taagagtgct taagaattat gtgctagtaa gtctcgctaa
     1801 gaagaggagt gttacaagat aaataaagaa gaggtcaggg aactaccggc ctctttttgt
     1861 ccgaaatagc gagaatgact ctagcttacc tgtatgtagg tccgtgctac acatcttgtt
     1921 aatgataggg agctgggatc agaaaataat tggtatatcg ttttctccta actttttaag
     1981 aaagtgcggg caaagtgggc tgttagggtg atggggttgc tctttcatga tcagtttttt
     2041 agcttgaaga aagcgtggtg atgagattag cttaaaaaag aacactaccg aaatggtagt
     2101 gtccactgat tttaggagag ctaagattgg tcatctaaca ggagtctaac tgtcatgcta
     2161 ataacagatt tgatagcgct gtccccactt ggaagaaata gagccttatt tttatttttt
     2221 ttgtgtttaa gggcttcttt tttgtgaggg ttttgttttg agtggcctat ggtcatcgca
     2281 gtccttttcc tttcaatagt gtgtttagga attggtggtt tagggctgac ggcaagaata
     2341 aaacacagta tgctaatagc taagataaga taaaactgtt ttttggtcat tgtttaggcc
     2401 tttctagttg aaaaatgtag ttgttgttag tttagccttt ttggtagctg gtatttaaaa
     2461 tagcattagc caagtggttg tactggctat ctaaacggta ctcagtattc ctcacgtctt
     2521 ttccagcaag gaaatacctt gtggtgtatg ctgaatcatt ccaggtagca tcaacgtagg
     2581 aattaacacc atgaatggta acgatgtttc aagcatggtg ctcattcaat ccttttttat
     2641 cacataccaa actgataagc ctgcagcttc tgccatatct ttaaacatga cggcataagc
     2701 ttgacaaaca ccacacttgc cacgataaag agctttagga gtatgattgt tgatgctgct
     2761 tacggttttg tgattggtgc taagttattt tgtggcgtaa gtgtattcgt tgattaaatg
     2821 gttataaata accttagcct tgtcgtagtc actggtgatc ggtttatctg taatattttt
     2881 ttgacaaagg ttttatattc cttatgaagg gctaccaaat tgtctttaag agtataggta
     2941 actgtaatat cactgttaac catgatacgt tggctttgtc taccaagtgt ataagtactg
     3001 gtacgacttt gggaagtaaa tgaagtaagg gttccataat aatcacctca ttcgtcgaga
     3061 gtggcaccag gtcgttgctg gttaatggag ctgatagttt gatagtaagt gttttgttca
     3121 gacacatcat aacggtatgc ccctgctgtt tcatcagctt tgaccttgct gtcaatggca
     3181 gcaaacgcac ttaagagtaa agctgccgct aggtcgctaa cactcttttt aatatttatt
     3241 agttttcctg ttacaaacta aatataaggg tttcccaaaa gtggattgtt tttaagcgaa
     3301 aggttatcca ccaacgataa tcaggatatc catgatcaat gtaaaaagca aagctttatt
     3361 aacttttttc atgactgtct cctttctgat tttctatttt gtacttgtat tatataatgg
     3421 atttagcaga ttttaatttt ttgttgtgaa agtgggaaaa atggaaaaag aactcggaaa
     3481 aaccttaagg cgattacgta agggtaagca ggttagcatt tcttttttag cagatgaata
     3541 cctgtccaag tcacaaattt caagatttga acgaggggaa tcagaaatca cctgcagtcg
     3601 cttgcttaat cttttggata aactgaatat tacgattgac gaatttgttt cggctcattc
     3661 caagacgcat acgcattttt tcacgctctt aagtcaggcg agaaaatgtt atgctgagaa
     3721 aaacgtggtt aaattgacca aactgttgaa ggattatgcc cataaagatt atgaacgaac
     3781 gatgattaaa gctattcttt tttctattga ctcctcaatt gcacctagtc aagaagaatt
     3841 gactcgcctc acagattatt tatttaaagt ggaacagtgg ggatattatg aaatcattct
     3901 tcttgggaat tgctcgcgct tcatgaatta caatacccta tttttattga ctaaggaaat
     3961 ggtagcatct tttgcttatt cggaacaaaa taaaaccaat aaaacgttag tgactcagtt
     4021 atccattaat tgtctcatta tcagtattga ccattcttgc tttgaacata gtcgctattt
     4081 gattaacaaa attgatcttt tgctgcgaga cgagctcaat ttttatgaaa agactgtttt
     4141 cttatatgtg catgggtatt ataaattaaa gcaggaagaa atgtctggag aagaggacat
     4201 gcggcaggcc ttgcagattt ttaagtatct tggagaggac tcattgtatt atagttataa
     4261 ggaacattac cgccaaatag tgctgggagg taagggggat gaggactggt ctgaggcaga
     4321 tttatgagtt gctttctatc agatgtgttc gtaaaataag aaataagaaa ggagaaggac
     4381 atctgtgttt tttgaaacgc agtcagtagc ctagacctga gtctattgag tgactttttt
     4441 atgctgagtt tattctttgt agcagcaaag ggtctagctg tcctttaaat aacggattat
     4501 gccagaatta ccagaagttg aaacggtccg acgagggctt gagactttag tgcttggcca
     4561 agaaattgtg gctgttacgc ttaaagtgcc aaaaatggtt aaaaccgact tagagacgtt
     4621 tgccctgacc ctacctggtc aaatcattca gtcagttggc cgtcggggaa aatatttatt
     4681 aattgatttg gggcaattag tgttggtatc acatttgcgg atggaaggca aatatttgct
     4741 ttttccagat gaggtccctg ataacaaaca ctttcatgtc ttttttgaat tgaaaaatgg
     4801 ttcgaccttg gtttaccaag atgtgcgtaa atttggaacc tttgatttga tagcaaaatc
     4861 tcaattatca gcgttttttg ccaaacgaaa actaggccct gaaccaaaga aagagacctt
     4921 taagttaaaa acctttgagg ctgctctgct atcctcccaa aaacccataa aaccacatct
     4981 gttagaccag accttggttg ctggtttagg gaatatttat gtggacgagg tactttgggc
     5041 tgctaaggtt catccagaaa ctgcgtcttc taggttgaat aaggcggaga taaaacggct
     5101 gcatgatgaa accatacgaa tcctagcttt aggaattgaa aagggcggtt cgaccgtccg
     5161 tacttaccgt aatgctttgg gagctgatgg caccatgcag gactatttgc aggtttatgg
     5221 tcaaactggg aaaccgtgtc ctcgttgtgg acaggctatt gtcaaattaa aagttggagg
     5281 aagggggacg cacatttgtc caaaatgcca gaaaaaaaga ccatgattat tggcatcaca
     5341 ggaggcattg catcaggaaa atcgactgtg gttaaggtca ttagaaaagc tggttatcag
     5401 gtgattgatg cggatcaagt ggtccatgac ttgcaagaaa aaggcggtcg tctttacgag
     5461 gctcttagag aagcttttgg gaatcagatt ttaaaagcag atggtgagtt agatcgcaca
     5521 aagctgtcag aaatgctttt ttcaaaccca gataatatgg caacatcctc agccattcaa
     5581 aatcaaatca ttaaggaaga attggcggct aagcgtgacc acttaacaca gagccaagcc
     5641 atttttttca tggatattcc ccttttaatg gaattgggct accaagactg gtttgatgcg
     5701 atttggctgg tttatgtaga tgctcagaca caattgcagc gcttaatggc tagaaatcgt
     5761 ttagacaaag gaaaagcaag gcagcgaata gccagtcagt taccaataga ggaaaaaaag
     5821 ccctatgcca gtctagtgat tgataatagt ggggatattg cagccttaat aaagcaagta
     5881 caatctgcgt tgttgtcatt agccaatccg aggtagctaa gctgagagat tcgtatcata
     5941 gctttcaaaa tcaagctatt tctgtctaaa actagctggt cccttttaaa ttagcgcatc
     6001 aagggttata tgttataata gtattaagag tgagaccctt ctaaacactt taacttatgg
     6061 gtaaacacat atcgacaagt atgatcatca aaaaagagga agcctatgac tacaatgaca
     6121 attgcaaaag gcaatcaacc gatagcctta caattaggga tgctaaatcg tcacggtttg
     6181 attgctggag cgactggaac aggtaaaact gtgaccttaa aagtgctagc agagcaatta
     6241 agtttagctg gtgtgccagt ctttttggca gatatcaaag gagacctgtc taatcttact
     6301 aaagcaggag aggtgactga taaattggct gcgcgtttag ccacaatcgg ggtaagtgat
     6361 taccagcctc aggcctttcc tgtaagaatg tgggatgttt ttggtcaaaa cggtcaaccc
     6421 ttacggacaa cgatttctga aatgggacct atgatgttgt cgcgtttatt gaatcttaat
     6481 gatacccaga caggtgtctt aaacatcgtc tttaaaatcg ccgacgagaa aggttggctt
     6541 ttgattgatt tgaaagactt gcaggccatc ttaaaagaag ttggtgacca tgcctcagac
     6601 tactccagtc attacggtaa tgtgaccaaa caatctgtcg gagctatcca aagaagtctc
     6661 ttgactttgg aacaagaagg ggccgaacaa ttttttggag agcctgcttt agaggtggct
     6721 gatttgatgc aattagatgt tgcttcgggt tatggagcca ttaacatttt gtcagcgact
     6781 aagcttttcc aatcacccac actttacacg accttcttac tttggttatt atcagagctg
     6841 tacgaattat tgccagaagt tggggatttg gacaaaccta agatggtttt cttttttgat
     6901 gaagctcact tgctcttcaa agatgcccct aaagttttct tggaaaaagt tgaacagatt
     6961 gtgcgactta ttcgttcaaa gggagttggg attttctttg tgactcaaaa cccacttgat
     7021 ttgccagaaa cggttttggc tcagcttgga aatcgtattc agcatgcctt gcgcgcttat
     7081 acaccgaaag aacaaaaggc ggttcgtgtc gctgcggata ctttccgaca aaatcctgac
     7141 ttagatgtgg caagggtgat tacagaacta gaagtcggcg aagctttgat ttctgttttg
     7201 aatgataagg gacaaccatc catcgttgaa cgtgcctata tcatgccgcc taagagtagc
     7261 tttgctgttt tgtcagatat agaaagtcag cagcttgtgc agtcctcacc ttttgccagt
     7321 aaatatagtc agtccattga tcgtgaatct gcttatgaaa aattagctgc taaggtttta
     7381 gaagacaacc gactggctca agaagcgata gcgacagcac aacgcgaaaa agaagctaaa
     7441 gaagccatca aggcacaagc tgctaccaaa aaagctaatc gccgttctgt tgggcgtccc
     7501 cgcaaaacag tcgtcgaaaa agcaacagat gcgtttatta gtacgacggt tagaacaatt
     7561 gggcgagaac tggtcagagg tttactgggt agtttacgta aacgatgaag gctatcagat
     7621 gagacttagc actattatgg gacactgttt ttggcagaaa tgtgttataa taatcaaagg
     7681 cccaatggaa agaagatgat gatctattag tgataaagcg gtaacgacag tgaactggcg
     7741 gcaaaatcta aaagtggctt ggcttggtaa cttctttact ggggcaagct tttcacttgt
     7801 tatgcctttt atggctctat atgtggaaaa tttaggtact ccgaaagaat tagtagaata
     7861 ctatgctggt ctggcagttg ctgtgacggc acttgcttca gctttatttg ctcctgtttg
     7921 ggggaagttg gctgatcgtt atggccgaaa acctatgatg ctgcgagcaa gttttgtcat
     7981 gacctttacc atgggtggtt tagctattat tcctaatgtg ttttggttac tcattttgag
     8041 attattaaca ggtgtctttg cgggctatgt gccaaatgcc actgccttga ttgccagcca
     8101 agccccaaaa gaggagtcag gttatgcttt aggcacatta gcaacaggag tgacagcagg
     8161 cgctttaatt ggtcctttac tagggggaat tttggcagag ctattaggaa ttcgacaagt
     8221 tttcttatta gttggtgtga tattattttt atgtttttta atgacagctg tttatgttaa
     8281 agaagagttt aagccgatta ggcgctttga gatgatacct acaaaagtca ttttaaagca
     8341 ggtaaaaagt ccccagatta tgcttggttt gtttgtgact agtatgatta ttcaaatttc
     8401 agctcaatca gtggccccca ttttatcatt gtatattcgt catcttggtc aaactcacaa
     8461 cttaatgttt acttcaggcc tggtagtttc ggccatgggg ttttctagct tatttagcag
     8521 ttcttactta ggaaaattag gagatcgatt tggcaatcat cggttattgt tagccgcttt
     8581 gtgttatagc tttatcatgt attttagcag tgccttagcg cagaccagtt ttcaattagg
     8641 agtactacgc tttgcttatg ggtttggtgt gggcgctttg atgccaagta ttaactcttt
     8701 actaactaag ttaacaccaa aagaaggtat ttctagagta tttgcctata atcaaatgtt
     8761 tagtaacctt ggtcaagtca ttggcccttt tatcggatca aatgtggctg tagtgttagg
     8821 ctaccgttct gttttttatg tgactagttt gattgtgttt gttaatttaa tatggagttt
     8881 gattatattt cgaaaatata ttaaagttaa ggatattgtg tgagagtaaa aattaattta
     8941 gaatgtagtg agtgtggcag taacaattat ctaaccagta aaaataaaag cagtcatccg
     9001 gaaaaaataa aagttcccaa atactgcccc aaggagagaa aagtgaccct gcatgttgaa
     9061 acttgataag aattgtgtta gaatggtcat gacaatagtg gaggaaataa catgtacaac
     9121 ttactactta cgatattgct agtactgtcg gtattgcttg tgattgctat ttttatgcaa
     9181 cctcaaaaaa acccaagtag caatgttttt gatagcagcg gttcagaagc cttgtttgaa
     9241 cgtacaaaag ctcgtggctt tgaagcattc atgcaacgat tcacagcagt tctagtattt
     9301 ttttggctag cgattgcact tgtgcttgcc attttatcaa gtaaataagg agtgagcttg
     9361 acagagttag tctagctcat ttttttatca gcgaaacgga ttgatatcct ccaacaaaca
     9421 aaacagaaat agaaattagg tatgatgaaa gaaagaatta tgacttacct caaggagcat
     9481 ggcaagtcca atgtgaacga cttggctgcg gccttggaga tggctggatc taagcatttt
     9541 cccagcctta ttaaaaccat ttccaaaatg gaaagtcaga gcctgttacg gttttcagat
     9601 gatggcagtc tggctcttag aaaagagcgt gaaaagaaaa aagaacctac tgttcagggt
     9661 gtttttcgtg ccaataaagc aggctttggt ttcttacatg tggatgagaa tgaagacgat
     9721 atgtttatcg gtcgtaatga tgttgggtat gctattgatg gtgatactgt cgaagtagtg
     9781 gttaaaaagc cagcagaccg tctcaaaggc acagcggctg aagctaaggt tgttgctatt
     9841 gttgaccgtt ctttaaaaac agctgttgga acctttattt tagatgatga caaaccaaaa
     9901 tatgctggtt atatcaggtc caaaaatcaa aagattcaac aaaaaatcta tatcaaaaaa
     9961 gagcctgttg tgcttaaagg cactgaaatc atcaaggttg atattgataa atacccgaca
    10021 cgcgggcacg attattttgt agccagtgtg cgtgatatcg taggccatca aggagacgtt
    10081 ggaattgatg tcctagaagt ccttgaatcg atggatatcg tgtcagagtt cccagcagaa
    10141 gttttagctg aggccaatgc tatttcagaa gcaccaactg ctaaagattt aataggccgt
    10201 gtggatttgc gtcaagaaac caccattact attgatggtg cggacgccaa agacttagat
    10261 gatgctatcc atattaagct attggataac ggtaactatg aacttggggt acatattgcg
    10321 gatgtctcat attatgtgac agaaggatct tcccttgata aggaagctat cgcccgtggc
    10381 acttctgtct atgtcaccga tcgtgtggtt ccgatgttac cagagcgttt gtcaaatggc
    10441 atctgctctt tgaaccctaa cgttgatcgt ttgacccagt cagccttaat ggaaattaac
    10501 ccgcaggggt atgtggtcaa ttatcaaatc tgtcaatcag tgattaagac aacttaccga
    10561 atgacgtata gtacggtcaa tgacatgatt gcaggagatg aagaagcgct ccaagaattc
    10621 gctagcattg ctgatgatgt gacccttatg gtaaccttac ataggatttt ggaaacgatg
    10681 cggtcaaaac gaggcgcctt gaattttgat acgcaagaag ctaaagttat tgttaatgac
    10741 aaaggaatgc cggttgatgt ggtgcttcgt caaaggggaa ttgcagagcg gatgattgaa
    10801 tcctttatgc tagcagccaa tgagtgtgtg gcagaacatt ttgcaaaagc taagttaccg
    10861 tttatctacc gtattcacga agaaccaaag gttgaaaaac ttcaacaatt tattgactac
    10921 gctagcacct ttggtattca cattcaagga acagccaaca agatttctca ggaagccttg
    10981 caagccttta tggcaaaagt cgaaggtcaa ccaggagcag aagtgctcaa catgctgctt
    11041 ctacgttcca tgcaacaagc aagatattct gaacataatc atgggcatta cggtttggcc
    11101 gcagaatatt acactcactt taccagtccg attcgtcgtt accctgactt gttggttcac
    11161 cgcatggttc gtgagtacaa tcaacctagt caagaaaagc gcgaccattt tgctcagatc
    11221 attccagagc tggcaacatc ttcttcacag ttagagcgtc gtgctattga tgctgaacgt
    11281 gtggttgaag ccatgaaaaa agctgagtat atggcagagt atgtcggcga agaatttgac
    11341 ggtatcgttt ccagtgtcgt taaatttggt ttttttgtag aattgccaaa tacgattgaa
    11401 ggtttggttc atatcactag cttaccggaa tactatcact ttaacgagag aacgctaagc
    11461 cttcaaggtg aaaaatcagg taaggtcttt aaagttggtc aacctattcg tgtgaaattg
    11521 gttaaggctg acaaggaaac tggtgacatt gactttgagt atttacctag cgactttgat
    11581 gtggttgaaa aaatcaagat atcggataaa gctagtcgac gagatcgccg taaatcctca
    11641 aaatcatcta aagggataaa gaaaaaagaa cctaaagaag tagccaaggc aaaaaccaag
    11701 ggtaaaacta aaaaagggtc taaaaaacca ttttacaaag aacaagcaaa aaagaagagt
    11761 cgtaaaagga gttaactatg gcaaaaggtg aaggtcatat actggcgcaa aataaaaagg
    11821 ctagacatga ttatcacatt gttgaaaccg ttgaagcagg gattgtctta acgggaactg
    11881 agattaaaag tgttcgtgca gcccgtattc aactgaaaga tggctttgcc caaattaaga
    11941 atggggaagc gtggttggtc aacgtgcata ttgcaccttt tgaacaaggt aatatttgga
    12001 acgctgatcc tgaacggacc cgcaaactgt tgctcaaaaa acgtgagatt acgcatctag
    12061 aaaatgaact taaaggatct ggcatgacct tagttcctct caaagtttac ctcaaggatg
    12121 gctttgctaa agttctgatt ggtctagcta aagggaaaca cgagtatgac aaacgcgaaa
    12181 ccattaaacg ccgtgatcag gaaagagata ttaaaaaaca aatgaaacac tacaatgcaa
    12241 ggtaaggtga atgagtatta tgataactaa aggacaagtt cgtttgttac gaacttattc
    12301 ttatgatagc aacttataca cgcagggatt agaacaactc aacaacaatc atatattact
    12361 tagtgccggt cgttatggtt tctcaaaagt aggggtgtat gaccttactc aagagatctt
    12421 ttcagaaaaa atagcttttc cagatacagt ttttgcagaa gggctaacag ttgttgagga
    12481 ttatttttgg ttactaacct ataaagaggg tgtagcctac aagtttgata aggctacctg
    12541 caattgttta ggagcctatc catttgaagg agatggctgg ggattagcct atgataagga
    12601 aaaccagtgt ctttggatga ctagtggaaa tgcttttttg cagaagcgag accccaaaga
    12661 ttttgcttta ttggataccg tactagttgc tatagaaagt gtccccatct caatgcttaa
    12721 cgaattagag tatgtagatg gttatctcta tgccaatatt tggcaaacca atactattgt
    12781 caaactccaa cctgattctg gaaaggtggt agccacctat gatattagtc ctttgttaaa
    12841 agccttaaat cttgataagt cccattaccc tgaccttaat gttttgaatg ggattgctca
    12901 tttagatcaa caacgtttct taattactgg caaactatac ccgctgatgt tagaagtagt
    12961 attagattaa gatgacaatt gagaaagacc tatgaaaagt ttccctaggt ctttcatttt
    13021 tagcacaaaa aaaaacagag ttagttcata tctctgtttt tttaaaatag gtttagtagc
    13081 gtcacagtca gtgagtagcg ccccctacac gttttaaatc ggaacgatct ttgaaatcga
    13141 caatggcaaa aatagcagcc tcaattcctc ttgtaatatc atcgaggttc atggcagctg
    13201 tattaggttt atcaacaacc tgttccatca taaagggaat atgcataaac ccagctttgg
    13261 catttggaca atatttatcc actaagtaaa gggcttgata catcaaatga ttgcaaacaa
    13321 aggtaccagc tgtattagaa acagaagcag gaagcccagc ctgatgaatg gcagcaacca
    13381 tcgctttgat tggcaaggtt gaaaaataag ctgctttacc atctgcacga ataggtgtat
    13441 caataggctg attcccttcg ttatcaggaa tgcgagcatc gtcttgatta atggcaacgc
    13501 gttctggcgt tagtccagtc cggccaccag cttgcccaat acaaaggact gcatcaggtt
    13561 gaaagctttc gatatgctgc tggagcacat cggcagattt ttgaaaaacc gttggaactt
    13621 caatacattt gatttctgct ccatgaatgg ttgctggcaa tttcttgata gcttcaaggg
    13681 caggattaat agcttcgccg ccaaagggat caaagcctgt tacaagaatt ttcataataa
    13741 tgtcctttca atgaataact gacgctacta acttagcaaa aaagttaata ataagcaagt
    13801 aaatacatta aggcaatgtg agtaataatt aaaacaaggg cgataggagc ttgctttttg
    13861 ataactgcat ttcgatcttt gatctccatc aaagcaacag gcaaggcatt aaagtttgct
    13921 gccattggtg ttaataaggt accacaaaaa ccagcagtca tagctaaagc accggcaata
    13981 atagggtcag ctcctaaagc aaaaacaaaa ggaacaccga taccggttgt aataacggta
    14041 aaggcagcaa aagcgtttcc cataatcata gtaaaaataa ccatgccaag cacataagcg
    14101 agaacaccaa agaagcggct atcagcaggt acaatctccc gaatgagaga agcaatcaca
    14161 tcaccaacac cagcagctgc aaaaatagct cctaaagctc ctaagagctg tggcaaaata
    14221 ccgcttgtgg acacttgttg gttcatccga ttattttcag ctaaaagagc agatggtttt
    14281 tgcttagtga ttattaaaat agcaatagtg gctaagatac cagcaatccc aatggcactt
    14341 ttactgaaat caggaaggat caaggcaaga agtagagaaa tcatagccat taacataact
    14401 ggtaagaaaa tccagttacc aatgcggtga gcactttctt cagctttttg ttcattaaag
    14461 gctggtaatg ttccaatacg aacttgctta aacaaggtta aaagagctag gacaatcacg
    14521 ataaaaccga taactttatt aggcaaaaag gcaccgccaa cgaaggtaac acccagcaat
    14581 ccccagaaca gagctgtccc aaaatagaca gggttggttt tatctttaaa ggtgcagtag
    14641 gctgtgtgaa acagttgcaa gccgataagg atatatatcg tttctaaaac aaggtttgca
    14701 atgttagcca ttagttatct cctttctgat gttgacgttc catttttttc tcaaagaggt
    14761 aattgtaaat agcaactata ataatagaga taatagcaat taaaatagaa gaaaatgcaa
    14821 ttttagcttg gttaccatca tagccaagct gttctaaagt tccagcgata agtaggacac
    14881 ctcctgcgcc aacaaaggta ttttgggcaa agaaattgcc aaagttttca ttggcagctg
    14941 ccatagcttt gatgtcatct ttttctgtat cggtcaactc ttctccaatg ttggctttag
    15001 cagcagcttc tcccataggt tgaatcaagg ggcgaacgaa ctgtggatgt ccccctagtc
    15061 gaatcgaaaa gagacttgct aattctcgaa taataaggta gagagtcaat aaacggccga
    15121 cggtaaggga ttgaacacgt tgaatcaact gagtagctcg gtgtttcagc ccataagttt
    15181 ctgacaagcc gataagcggt aaagtgatga agaaaatggt tagcaaacgt tgattggtaa
    15241 attcttttcc taaaatatct agaaaatcaa taaacgaaat tcctgaaacc agcgcggtaa
    15301 caagtcctgc aacaactacg gtagcgatag cattaaattt taaaataaac cctaacacga
    15361 taatcacaat accgattaat ttaatccact ccataaagaa ctcctttttc aatagtatga
    15421 cgattataac attagtcgct aggatttgca aaaaggctca acctaatagt tccttttcta
    15481 cttaaagtgt taaggaaggt gatactattt tggaaaggtc attatcattt ggtataacgg
    15541 gcttaaaaag aaagcttcgc gcacagaagg agtaggaaac gattgatgag aaaaatgttt
    15601 taatttaatg tttttctttg ataatataga gaggcctttt tttagtttca aggaatattt
    15661 ttgaaatata ttttccaata atacccatgc aaaagagctg aatgcctccc atgaataaaa
    15721 taatagagac agtgctggcc caaccagaga caggatcacc aaagagtatc tttctgataa
    15781 tgataaataa gatggcgaaa atagaaatca aaaagctgaa agtccctgtc caggtagcaa
    15841 tggttaacgg catttctgaa aagttgataa agccatctaa agaatatcgg agcaactccc
    15901 aaaaatgcca acgacttttt ccatatttgc gtttttggtt ttcaaaacta agataggtga
    15961 tacgataacc aacccacgaa aagatccctt ttgaaaaacg attaacctct cccaactcaa
    16021 gaatgctatc aacgacttgt ctggtcatta accgataatc ccgaactcca ttgaccattt
    16081 cagtatctga taagtgtttg atcagtccat aaaatagatt cgaacacatt gaacgaatta
    16141 gtggttctcc ttgtctattt tgacgcctgg tgccaacgat gtcataaccc tcttttagct
    16201 tagcgtacat aattggcaaa agttcgggtg gatcttgcag atccacatcc atcacagtaa
    16261 tgtaattgcc tttggcttct tttagtccag ctaagagtcc agcttccttg ccaaaatggc
    16321 gtgaaaaaga cagataatgc acatttggaa agcgagcagc tagctcacgc aaaataccca
    16381 aggtgttatc cttagaacca tcatcaataa aaatgtattc aaaagcaagt tggttggtca
    16441 tggacgtttc tagttgatgc atttcttcaa aataagggag aatgtttgct tcttcattaa
    16501 agcaggggac aatgatagat agtagtgtca tagacttttc tttcaaatgg aattttaggg
    16561 caattgtaac acaaaagctg agatatttca aaactctgtt aataatgaga ttgtcccaat
    16621 cgtcaggtta aaaaataaaa caacagaagc tttaaagctt ctgttgttaa tagtattagt
    16681 tgtttaaatc aatgacttca attttgtagc catctggatc ctgaatgaaa taatagcggg
    16741 cagatttgtc agccagttct ttgatatcgg taactggaaa acctgcttgt cgatgttttt
    16801 tatggtctgc ttcaaaatgt tcagagccaa gggcaatatg accatagcca tttcctaagt
    16861 cgtagtcgcc atgaccataa ttgtaggtta attctaattc ataactttct ccttctaaag
    16921 ccagataaac aagagtaaat tgactatctg gaaaatcttt acgatagttt tcctcaaaag
    16981 ggaaggcgct tgtgtaaaaa gctaccgact ggtcaaggtc tttgacgcgg atacaggtat
    17041 gtaatgcttt cattttaatc tccttattta acgactgaaa tcacttcttc tttaggctta
    17101 cgaacttgag catgtttggg atctcgcaaa cgatagccta gggataacat gctagcaatg
    17161 ccttcttttt ctaaatcaat cacattatgc ttagctagga tatgattgac cttatcataa
    17221 tgaaagcctt caatagggca agtatcaatg cccaaaagag cagctgtcat catcatatta
    17281 ccaagagcga tataggtttg tttagctgtc caatcaaaga gtgcccgagg attatctgcc
    17341 atatccatgt cctctttttg gaaagattca tagagtttta ggcggctgtt gagaccatca
    17401 ccttctttga taccacgtcg taaaaggcta tttttgatag cagggctatc gtatcttgca
    17461 tgtttttcag ctattaaaag aataaagtga ctagctgtct ctagttgata ctgggccccc
    17521 caggcaaagg gcttgatttc ttctttaata ggcttgttgt ctaaaacgat aaagcgccag
    17581 ccttctaagc caacagaaga agggcttaac caagcagcat caaggataag ggctaaatcc
    17641 tcatcagaaa tcttttcttc cttataaaca cgaacggctg ttctaaagtg tagtgcttgc
    17701 tgtatttggt gatgaatggt ttgatccata cgaatacctt cctttcgcga gggtttgttt
    17761 aaccagatga taggggctta gccttcaaaa taaagcaact cttttggagt atgggtaaag
    17821 acttcaaagc catttttagt gacatggcca cagtcttcga tgcgcacacc gacctttcct
    17881 ggaatgtaaa tgcctggttc cacagagaag cacatacctt cttcaaggac caagtcattg
    17941 ccagccatga tggagggaaa ttcgtggaca tccatgccga taccatgtcc caagcggtgg
    18001 ttgaagtact caccatatcc agccttctca atcacttgac gagcagcagc atctacttga
    18061 gcagctgtta cacctggttt gataaagtca atagccgcta gttgtgcctc taggcagaga
    18121 ttgtagatat cgattttaaa ttggtctggc tgaccaacag tcacagttct ggtcatatca
    18181 ctggtgtagc ctaaggtctc aacacctaag tcaaaaagaa gtagggcatt gttttcaatg
    18241 ttatttgttc caggaatgcc atggggattg gctgcattat ttccagttaa gaccatagtg
    18301 tcaaagctca ttttatgaat gccttgtttt ttcatttcaa actcaatttg agcgatgacg
    18361 tctgtttcgg tagcatctaa ggaaatattg tcaaaaccaa cttgaacagc cttatcagcg
    18421 aactgcccgg caatcatcat tttattgatt tcatcagctg atttgatgag gcgcatgcct
    18481 tggacataag gggttagatt gttaaattgc cctgaaaaga tagtctgcaa gccatggaac
    18541 ttattgacgt taaggtggtc aaattcagca taaatggttt tggctgctgt atttggtaaa
    18601 acggccttga tcttttccca aggattttca gagtcaacat aaccaaacac aggaaatgat
    18661 atggcctggc tagctctggc cacctcaagg gcaggtacaa aaagcacagg agctaaatca
    18721 tggtagacaa acaagaacag ttgtctttca tgtgggtcac agaagaatcc agttaaatag
    18781 ttaatcgtaa caggatctga gaaaatcgcc aattcagctc ccttttggtc aagatacaaa
    18841 cgtatttggt ctaattttgt cataggctaa ccttctttct acttactatt ttttcaaaaa
    18901 aagcttaaaa aatcaagctt cgagttaatt tttgaaaact ttttcaaaaa ttaacctata
    18961 acacttgaaa gtggttacaa atcatgctaa aatacttttt gaaagcgtca ttttcaaata
    19021 gaaaggaaga taaaaaatga atacagatga taccattaca atttatgatg ttgcccgtga
    19081 agctggtgtt tcaatggcaa ccgttagtcg tgttgttaat ggcaataaaa atgttaagga
    19141 aaatacacgt aagaaagttt tagaagttat tgatcgcctt gactatcgtc ccaatgctgt
    19201 cgcgcgtggt ctcgccagca aaaagacaac aaccgttggc gttgtgattc caaatattgc
    19261 aaatagttat ttttctatct tagctaaggg tattgacgat atcgccgcta tgtacaaata
    19321 taatattgtg cttgcctcca gtgatgaaga tgatgacaag gaggttaatg ttgtcaatac
    19381 cctttttgcc aagcaagtgg atggtattat ttttatgggg catcacttga cagaaaaaat
    19441 ccgggccgag ttttcacgct ctcgtactcc agttgttttg gcaggaactg tagatcttga
    19501 tcatcaatta ccaagcgtca acattgacta tagagctgcg gtgtcaaacg ttgttgatat
    19561 tttagctgaa aatcataagt gtatcgcttt tgtgtcagga ccactcattg atgatatcaa
    19621 tggtaaagtg cgcttagcag gttacaaaga agggttgaag cacaataagc ttgacttcaa
    19681 agaaggtctt gtttttgaag cgaactattc ttataaagaa ggatttgaat tggcgcagcg
    19741 cgtcattaac tcaggagcaa cagcggctta tgtggctgaa gatgaattgg cagcaggcct
    19801 tttaaacggc ttgtttgaag caggtaaacg cgtaccagag gactttgaaa tcatcaccag
    19861 caacgattca ccagtggttc aatacactcg tcccaatttg agttctatca gtcaacctgt
    19921 ttatgactta ggtgctgtta gtatgcggat gttgactaaa atcatgaaca aagaagagtt
    19981 ggaagaaaaa gaaattcttt tgaatcatgg tattaaaaaa cgtgggacaa ctaagtaact
    20041 gtgacttatg agcaccatct aacaaaaagt atcacaatag actgtttctt caatactaaa
    20101 atcagcctta gggctgattt ttgcatgtct tagtgaaaaa tactataaaa tgagctataa
    20161 tagaacttat gaaagtctta ttgtatttag aagcagaaaa ttatctaaga aaatcaggaa
    20221 ttggtcgagc gattaagcat caggctaaag ccttgtcact tgttggtcaa cattttacga
    20281 ctaatccaag agaaacttat gatttggttc atctcaatac ctatggttta aaaagttggc
    20341 tgctgatgat aaaagcacaa aaagctggta agaaggttat catgcatggg cattctacag
    20401 aagaagattt tagaaattct tttatttttt caaatctatt atctccttgg tttaaaaaat
    20461 acctttgtca cttttacaat aaggcagatg ctatcattac ccctacccta tattctaagt
    20521 ctttgattga gagttatgga gtgaagtcgc ctatttttgc agtgtcaaat gggattgatt
    20581 tggagcagta cggagcagat tctaaaaagg aagcagcttt tcgtcgctac tttgacatta
    20641 aagagggtga aaaagtggtt atgggagcag gattattttt tctgaggaaa ggaattgatg
    20701 actttgtcaa agttgcccaa gctatgccag atattcgttt tatctggttt ggcgagacca
    20761 acaaatgggt cattcctgct caagttcgcc aaatggtcaa tggtaaccac ccgaaaaatc
    20821 ttattttccc aggatacatt aaaggggatg tttatgaagg tgccatgact ggtgcagatg
    20881 cctttttctt tccaagtcgt gaagaaacag aaggcattgt tgtcttagaa gccttggcca
    20941 gtcgccagca ccttgtttta cgtgatatac cagtttacta cggatgggtt gatcaaagta
    21001 gtgcggaatt agcaaccgat ataccaggtt ttatagaagc tctgaaaaaa gtcttttctg
    21061 gtgccagcaa caaagttgaa gctggttaca aggttgccca gagtcgtcgc ctagaaacgg
    21121 ttggccatgc cttagtagat gtctataaaa aagtaatgga gttataagat gcgtataggt
    21181 ctattcacag atacctattt tccacaagtt tcaggagtcg ctactagtat tcgtacgtta
    21241 aaagaagagc tagaaaaaga aggtcacgaa gtttatattt tcaccactac tgatagagat
    21301 gtcaaacgct ttgaagaccc gaccattatt cgactgccaa gtgttccttt tgtgtcattt
    21361 acggatagac gtgtggttta tcgtggcctc atttcgtcat acaaaattgc aaaacactat
    21421 aatcttgata ttattcatac gcaaactgag tttagcttag gcttattagg gaaaatgata
    21481 ggcaaagctt tgcgaattcc tgttgtccat acttaccata cccaatatga ggactacgtg
    21541 agttatattg ccaacggaaa aatcattcga ccaagtatgg tcaaacctct tcttaggggc
    21601 tatttgaagg atttggatgg ggttatctgc ccaagtagga ttgtcctcaa tcttctagaa
    21661 ggttacgaag ttactatccc taagcgggtt atcccaacag gcattccttt ggaaaaatat
    21721 attcgtgatg acatcacagc agaagaagta accaacttaa aagcagaatt gggcattgct
    21781 ggtgatgaaa ccatgttatt gagtttgtca cggatttctt atgaaaaaaa tattcaagct
    21841 atcatcaatc agatgccagc tattttggct gaaaatgcca agataaagct tattattgta
    21901 ggaaatggcc cctatttgca agatttgaaa cacttggcga tgcagttaga ggttgacaaa
    21961 cacgtgacct ttacaggcat ggtgcctcat gataaggttg ctctgtacta taaggcttgt
    22021 gatttcttta tctcagcatc aactagtgag actcagggct tgacctatat tgaaagtttg
    22081 gctagtggca ctcctattat tgctcatggc aatccttatt tagatgatgt ggtgactgaa
    22141 aaaatgtttg gcactcttta ttacgctgaa acagatttaa ctgatgctat tattgatgcc
    22201 atactaaaaa caccagttat ggataaacgg ttattagcaa aaaaacgtta tgaaatctca
    22261 gcacagcact ttggaaaatc tatttacacg ttctatttag atacgttaat tgctagaaat
    22321 agcaaagaag ctcaaaagct gagtctttat cttaatcatt ctggtaaaag tagttctcta
    22381 aaattagtgc aaggtgctat tcacttgcct aaacgtgctg ctaaggtcac agctatcacc
    22441 tcagtaaaag tagtcaaggc tcctatcaag ctggtccatg ctatcaaaga ttttctggat
    22501 taagacttgt aaatttttga aaacttgcta taattatctt gaagacaagt tagattggac
    22561 agaatctttt aagcgagtgc tggttggtgg aaagagcaca aggatagcta atctgatact
    22621 ccttcctggt ttttatgcaa acataaaagg gtggccccct tatcgccact agaggtgcaa
    22681 ggcatgtttt ttgtcctgca taaattaagg tggaaccacg ctgattgcgt cctttgggat
    22741 gcggtcagtt tttttgtttt ggaggggatt agccttgttt ttaaggacta gggagggtag
    22801 attcgtgaat aaggtattgt tcttctacgt ggtggtgttg agctattcac taacctcttg
    22861 tccctaattt gtcttactat ccatgtttta gtggaaatct taactgactt aaaggagaaa
    22921 gcaaatgatt aagattactt ttccagatgg cgccgtgcgt gaatttgaat ctggcgtaac
    22981 aacgtttgac attgctgagt ccatcagcaa atcattggct aaaaaagctt tagctggtaa
    23041 gttcaatgat caactcattg acaccactcg tgccattgaa gaagatggca gtattgaaat
    23101 cgtgacacct gatcacaaag atgcttatga ggtgcttcgt cactctgcag cccatttatt
    23161 tgcccaagct gcaaaacgct tgttcccaaa tctttatttg ggtgtgggcc ctgccattgc
    23221 agaaggcttt tactatgata cagataatgc agaaggccaa atttcaaacg aagatttgcc
    23281 acgtatcgaa gctgaaatgc aaaaaatcgt gacagaaaat tacccatgta tccgtgaaga
    23341 agtgaccaaa gaagaagctt tggaattgtt caaagatgat ccttacaagg tagaattgat
    23401 taatgagcat gctggtgctg gcttgacggt ttaccgtcaa ggtgaatttg tggatctttg
    23461 ccgtggccct catgtgccat caacaggccg tatccaagtc ttccacttgc tcaatgtggc
    23521 gggtgcttac tggcgtggta acagcgacaa taacatgatg caacgtatct atggaacagc
    23581 ttggtttgat aaaaaagacc tcaaagctta cttgactcgt ctagaagaag ccaaagaacg
    23641 tgatcaccgt aagcttggta aagagcttga cttgttcatg attagccaag aagttggtca
    23701 aggcttgccg ttttggttac cagatggagc gactattcgt cgtacacttg agcgctacat
    23761 cacagataaa gaattagcat caggctacca acacgtttac acaccaccac ttgcttctgt
    23821 agaattgtac aagacatcag gtcattggga tcattatcaa gaagatatgt tccctgtaat
    23881 ggatatggga gatggtgagg agtttgttct tcgtccaatg aactgcccac accacattca
    23941 agtgtataaa aatcatgtgc gttcttatcg tgaattgcct attcgtattg ccgagcttgg
    24001 catgatgcac cgttacgaaa aatcaggtgc cctatcagga cttcaacggg tacgtgaaat
    24061 gaccttgaat gatggccaca ttttcgtaac accagagcaa atccaggaag aatttcaacg
    24121 tgcccttcaa ttaatcattg atgtttatgc tgacttcaac ttgactgatt atcgttttcg
    24181 tttgtcatac cgagacccta acgatactca taaatattat gacaatgatg agatgtggga
    24241 aaatgctcaa agtatgctta aagctgcact tgatgagatg ggtgtagatt actttgaagc
    24301 agaaggtgaa gcagcctttt atgggcctaa gcttgatatt caggtgaaaa cagctcttgg
    24361 taacgaagaa accctatcaa ccattcagtt ggacttcttg ttgccagaac gctttgacct
    24421 taaatacatt ggtgcagatg gcgaagaaca ccgtccagtc atgattcacc gtggtgttat
    24481 ctcaactatg gaacgtttca ctgctatcct tattgaaact tacaagggtg ctttcccaac
    24541 ttggttggca cctcaccaaa taaccgtgat tccaatttca aatgaagccc acattgacta
    24601 tgcttgggaa gtagcaaaaa cccttcgtga ccgcggtgtt cgtgcagatg tcgatgaccg
    24661 caatgaaaaa atgcagtaca agattcgtgc gtctcaaacc agcaaaattc cttaccaatt
    24721 aattgttggg gacaaagaaa tggaagacaa atcagtcaat gttcgccgct atggtagcaa
    24781 ggcgactcac accgaatctg tggaagaatt tgtggaaaac atcttggcag acattgctcg
    24841 caagtcacgt ccagatgcac aagcttaatc aatggcaaaa agaggtcctt atgggcttct
    24901 ttttctttct taaaaaatta agcaaacggt tgcaccttct ttttcatggt gttataataa
    24961 attgtttagt aacggtgata agacgataac agaaacgagg aatggtaaat ggtcatgata
    25021 gaagtgtccc accttcaaaa aaatttttcc aaaaccatta aagagccagg attaaaggga
    25081 gccttgaagt cctttgttca tccccaaaga gaaatctttg aggtggttaa ggacttatct
    25141 tttgaggtac ccaaagggca aattttaggt tttattggag ccaatggtgc aggaaaatca
    25201 acaacgatta agatgttaac aggtatttta aagcctacat caggttactg tcgtattaac
    25261 ggaaagattc cacaagataa tcgtcaagat tatgtgagag acattggagc tgtttttggt
    25321 caacgaacac aactatggtg ggatttggcc ttgcaagaga cctatgtcgt tttaaaagaa
    25381 atttacgatg tgcctgaaaa agcctttcgc aagcgcatgg attttttaaa tgaggttttg
    25441 gacctgaatg agtttattaa ggatcctgtc cggaccttat cactcggtca gcggatgcga
    25501 gctgatattg ctgcttcctt gttgcataat cctaaagtat tgtttttaga tgaaccaacg
    25561 attggacttg atgtttctgt gaaggacaac attcggcgtg ccattactca aattaatcaa
    25621 gaagaagaga caactatttt actgacgacc catgatttga gtgatattga acagctctgt
    25681 gatcggatta tcatgattga taaagggcaa gaaatctttg atggaacggt gatccaatta
    25741 aagcaaagct ttggaaaaat gaagagtctg tcttttgagt tgaagccagg gcaggagcag
    25801 gtggtctcac agtttatggg cttacctgac atcacagtgg aacggcatga gcttagttta
    25861 gacattcaat atgacagttc gcgctatcaa acagcggaca ttattcaaaa aaccatagct
    25921 gattttgcgg tcagggattt gaagatgact gatgtagata ttgaggatat tgttcgtcgt
    25981 ttctaccgaa aggagcttta agatgtggtc attttggaaa cgttatagac cctttctcag
    26041 tgcagggatt caggaattaa taacctatcg cgttaatttc tttttgtatc gtattggaga
    26101 tgtcatgggg gcttttgtgg cttattacct ctggaaggct gtttttgatt cgtctaagca
    26161 atccttaatc aatggtttta ctctgtctga catgaccttt tacattatca tgagttttgt
    26221 gaccacttta ctgaccaaat cagacagctc ctttatgatt ggcgaagaag tgaaagatgg
    26281 ttctatcatt atgcgcctgc ttcgaccagt tcattttgca gcctcttacc tctttatgga
    26341 aattggtttt cgctggattg tgctaatgag tgtcggcttt ccttttttaa tggtcttatc
    26401 tggtattaaa gtcatggcgg ggctgtctat cttgcaagtc ctagccagca gttgtctgta
    26461 tttagttagc cttttattag cttttttaat caatttttat ttcaacattt gttttggctt
    26521 ttcagcattt gtctttaaaa acctttgggg gtctaattta ttgaaaaatg ccttggttgc
    26581 ctttatgtca ggcagtttga ttccattggc tttttttcct aaaatggttt ctatagtgct
    26641 tagttttcta ccgttttcct ctttggttta cacgccagtt atgattgtca ttgggaaata
    26701 cagccttagt cagataatgg tggccctaag tttgcaaatc ttttggttac tggtgatggt
    26761 agtcttatcg caagtcatct ggaaaaaggt tcagtaccat ttaacgattc aaggagggtg
    26821 agatggcaaa attgagacgt atgcacgcta tttttatcaa acaatacctc aaacaaatta
    26881 tggaatacaa ggttgatttt gtggtgggag tgctaggtgt ttttctcact cagggactta
    26941 atctgctctt tttatcggta cttttccaac atatcccttc tttagaaggc tggacgtttg
    27001 aacaaattgc ttttatttat ggcttttctt tgattccaaa gggaattgat cacctctttt
    27061 ttgacaatct ttgggcttta gggcaacggc ttgtccgcaa aggagaattt gacaagtacc
    27121 tcactagacc aattagtcct ttatttcatg ttttggttga gacatttcaa gtggatgcct
    27181 tgggtgaatt attggttggg gttatcttat tagtgaccac ggctggtagt atcgtatgga
    27241 ctcttcctaa ggtgcttttg tttattttgg ttattccttt tgcgaccttg atttacacct
    27301 ctttaaaaat tgcgaccgcc agcatttctt tttggaccaa gcagtctggg gcagttatct
    27361 atatttttta catgttcaat gacttttcta agtaccctat gtccatttac cattcctttt
    27421 tgcggtggtt aatcagtttt atcattccct ttgcttttac agcttattac cctgcttctt
    27481 attttttaac aggtcaacac ctgctcttta atattggagg cttggtagtg gcgtcgttac
    27541 tggttttggc cttgtcgctt aagctttgga aatggggcct ggatgcttat gaaagtgcag
    27601 gttcctagag agactcttaa acaaattgaa aatcgtttag gtcagaatat gaaaacctag
    27661 ataatgaagg aaggcagctg ttgtaaaaac ggctgctttt ttttgtgatg gtttaccaag
    27721 cgtaggcatt ggttggaacc atcatcagca gattggtcta aattaaggac ggtaaaataa
    27781 cataagcaga tatatttcaa gtggttgcat gcaattgcta gataacgttt atggaacttt
    27841 gagatctttt gcctttatga gacctgtcaa atctagtaac gatactagct tagcagatgc
    27901 cttgcaggct gatacagaca tggcttttat tttagttaga ggcattaact atcaataaat
    27961 agtaaagaca aggtttgtca ataccataaa aaagttaagt gtcacagctt agctttttta
    28021 tggtgtctaa ttctttattc tatataagat tttcttttct taggaatggt tttccagtat
    28081 aataaagtca ccctgtatca aaaacaaagg ttacagtttg aatgttaaag caacaaagta
    28141 agtgacttct acgacaatag ttgtgggact tgacatttca atgacgttag aggattttat
    28201 agattttatt gatagcacac tagcgagact aaagagattc tctaaattaa tttaggtgta
    28261 tttttagcag ttattagttc aaaaaagaaa accatcagaa ataattatat aataaccatt
    28321 taaggacatc gaaaataaag gaggtcaata taatgacgga tgtttatatt gctgcaggcc
    28381 ttagaacccc tatcggttta gtagggaaac aatttgctaa agaacaacca gaaatccttg
    28441 gagcaaagct catcaacgct ttacaaaata agtatccagt tcccattgac caagtgattt
    28501 gtggcaatac cgtcggaacg ggtggtaata ttgggcgctt gatgaccctg tattctcatt
    28561 taggagaatc tgtctctgct ttgacggttg atatgcagtg tgcatcagct ggtgcagctc
    28621 tttccgtggg ttatgctaaa atcaaggcag gtatggcaag caacctttta gtgggaggga
    28681 ttgaaagcag ctccttacaa cctgaatcgg tatatgcttc agctgattgg cgccaaggag
    28741 cctacaaggt agctcagttt tctccagata gtatcagccc ttttgcgatg attgaggggg
    28801 cagaacgagt ggcaagagag tatggcttta caaaggagta tttgaatcac tggacattga
    28861 gaagtcatca aaaggctagt tattgccagg agcaagccct gttagctgat cttattctag
    28921 acctgccagg agccagtgat caaggtattc gaccgcactt gtcaagtaag gtgttgtcaa
    28981 aggtaccccc tatcttagga gaagatcacg tgattagtgc agccaatgcc tgcctcaccc
    29041 atgatgctgc tgccttttta cagataagta gtcagccttc agcttttaaa ctgattgatg
    29101 tggtagaagt agcaggagac ccacagcgta gccctttaat ggtgattaag gctagtcaag
    29161 tccttttgga aaaacatggt ctagggatgg cagatatgac agcgattgaa tggaacgaag
    29221 cctttgccgt tattgatggt ctatttgaaa cccattatcc agatttattg gaccgctata
    29281 atatatttgg tggtgcatta gcttatggtc atccctatgg tgcctcagca gccattataa
    29341 tattgcactt aatgagggct ttagagatta aaaatggacg ctatggaata gctgctatag
    29401 cagcagctgg tggccaaggg tttgctgttt tactaaaata tcataaggag tttagtcatg
    29461 ctgacaaagc tagaatattg ggcaaagcaa tgcccaaata aaaaagctat cgtagccgat
    29521 cagataagct tgacttatca agagctatgg caagcggttt taataaagga tcatacaata
    29581 aaagacagtg taccatatat catcagtcat agtcgctatc ttaatcagtt actctctttt
    29641 ttacgaggat taaaagaagg cagttgtcct atcattttac accctaatat ctcaggtaca
    29701 tttcagcagc aaataaaaca cgtcgatagt gagcttctta aaaaagctga ttttgctgtt
    29761 ttgagttcgg gaacaactgg caaagcaaaa ttattttggc gttgtctatc aacttggacg
    29821 agactttttg attatcaaaa taaggtgttt ggtatgactg gtaatagttg tctattctta
    29881 catggtagtt ttagttttac tggcaatctt aacttagcat tagctcaact atgggccggg
    29941 ggatgtctgg ttttaagcca aaagctgtct ttgaaaacgt ggttaagctt atggcaagca
    30001 aaaaaggtga gtcaccttta ccttttaccg acctacctaa atcgcttgct accttatttg
    30061 actaagaaca acatgactgc gactcactta ttgacctctt cgcaaatgat atcacaagaa
    30121 ttactaagac attattacaa aaaatttcct cagcttgaaa ttgtcatttt ctacggggct
    30181 agtgaattat cttttataac gtggtgtaat ggcagagctg ctgtcaaaat taatggtttg
    30241 gtaggacagc cctttcctga tgtgtctatc agtttcaaag ataaggaaat ttttgtagag
    30301 actccttata gtgtagaagg aatgtcacaa ccatacagtg tctcagactt aggaaaaatg
    30361 agcccagcgg gtttaatttt agaagggcga caagatgact gggttaatca acgaggagtg
    30421 aaatgccacc tgcctagcct agttgaactc gctcaccaag cgccaaacgt caaagaagcg
    30481 cacgctttaa agataggaaa aggagaaaac gaaaccctaa tattagtatt agttttgact
    30541 aagaaggatt gcctagcacc tattaaagac tttttagctc tttatttaaa ctctggacaa
    30601 cttcccaagt actatcttgt gattgattgt ttgcctttaa aagataatgg taaaattaat
    30661 cgagaagttc ttttaaataa aatacccaaa cagtggctta gttaaccact tcaggtttcg
    30721 ttttgcttat agtgagatac aagtgacgat tcagctttag atgtgttata atatggtcaa
    30781 aaaagatgag gagaaggcca tgaaacaagc tatcttagat cgctatcagg ccttgaaatg
    30841 ctatcaaaac gcaggtttat caaaccaagc atttcgtgct atagctaaag agcctatcat
    30901 tgataatcga cttggttctc caactttctg ggtaatatgg cctattgaaa aagaaaacca
    30961 atcagctaag cagttactaa cgtttcttct tgatttggta gagatgccat ttgagctaag
    31021 tggtcagttg catgaaactc aaacgctact cacccgattc catccatctc tattgccaga
    31081 tcatatgttt tggaaagagt tggctagctt agttgatcaa gcttttcctg gcaaaacact
    31141 aagccaagca ggtgagcttg aaaagcgttt gcatcaattt cgttatgtca tctctagtca
    31201 acaagctcaa tctatcagaa accattataa aatgattgag atgacagacg cccaagctct
    31261 ggcccttttt ttgaggtcta aaaaagggcc ttgtttgtgg cggcaagcac cagattatac
    31321 cttgatggat tctgccaggt tacataataa actaagattt gaagataata aagtcatttt
    31381 tccaagtcaa gaagtttcct ataatataaa agtacttctt tggtttcata ccgaatttat
    31441 tctagatagc acaggctttt ttcttaatga agttgatgca gaagtagtga ccgaaaaagg
    31501 aattgtcaat ggtgcatctt ttaactatgg cacagatggt cctagacatt gggatttaga
    31561 tgttgatccg attagccgtc acgatcctca gtttagaaga gacaccctta aaggatttcg
    31621 aacgccaaaa agagtatttc gtcagtggtt tagagctcaa aaagatgact ttatgttctc
    31681 ttattttaat gccaaaggac tttttgctta ccacaacaag agtagttttg ccagagtcaa
    31741 aaaatctgct aagcaattca aacgccaaat tcatcctata aagggttggt tttagaaagt
    31801 actctatttg taacggtagt cgtcattgtc aattaggctg aatttttggt ataatcaggt
    31861 agaaataatt tagaaaaata tagttttgtg attttttatt aaccacaaaa atcacaaatt
    31921 gtaatatcaa ttacaagaac tttctgaggt atagacatga aaaaaatact tattgtggat
    31981 gatgaaaaac cgatttctga cattattaag tttaatttga caaaagaagg ttatgacatt
    32041 gttacagctt ttgatggacg cgaagcggta accatttttg aagaagaaaa gccagattta
    32101 attattcttg atttgatgct ccctgagttg gacggtcttg aagtagccaa ggaaattcgt
    32161 aaaaccagtc atgtcccgat tattatgttg tcggctaaag atagtgagtt tgacaaggtt
    32221 attggacttg aaattggggc tgatgattac gtgaccaagc ccttttctaa tcgggaattg
    32281 ctggcgcgtg tcaaggctca tctgcgtcgt accgaaacta ttgaaacggc tgttgcagaa
    32341 gaaaatgctt cttcaggtac acaggaactg accattggta atttacagat tttaccagat
    32401 gcgtttgttg ctaaaaaaca tggtcaagag gtagagttga cccatcgtga atttgaacta
    32461 ttgcatcatc tagctaacca tatggggcag gtgatgacac gagaacactt attggaaatt
    32521 gtttggggat atgattattt tggcgatgtg cgcacggttg atgtgactgt tcgtcgtctc
    32581 cgtgaaaaaa ttgaagacac accaagtcgt cctgagtata ttttaacaag acgtggtgtt
    32641 gggtactaca tgaaatctta tgactagaga tatcattgga aacttatcca catttgaatt
    32701 agcgatcctt atcttacttg tttttgttgc tttttacttt atccatcttg cggtgcgtga
    32761 ttaccgaaat gcacgtatta ttcggatgat gagccataaa atccgagact tgattaatgg
    32821 tcgctatact gatataatcg acgaaaaagc agacgttgag ttaatggagc tttcagacca
    32881 gttaaatgac ctgtcagatg tttttcgctt gacgcatgaa aatcttgccc aagaaaaaaa
    32941 tcgcttggca agtattttgg cttatatgtc agatggtgta cttgctacag accggtctgg
    33001 taaaatcatc atgattaacg agacagctcg caagcaatta aatttaagta aagaagaggc
    33061 actaaagaaa aacattacag atttgttaga aggtgatact tcatatacct accgtgattt
    33121 ggtatccaaa acaccagtgg taactgttaa tagccgaaat gatatgggtg agtttgtctc
    33181 attacgcttg cgctttgcgt tgaataggag agagagtggt tttatttcgg gcttggttgt
    33241 ggtgctccat gacaccacag aacaggaaaa agaagaacgt gaacgccgtc tttttgtctc
    33301 taatgtaagt catgaattaa ggaccccttt aacttcggtt aaatcctact tggaggctct
    33361 tgatgaaggt gcacttaaag aagatattgc tccaagtttc ataaaagttt ctcttgatga
    33421 aactaatcgg atgatgcgta tgatttcaga tcttttaaac ctgtctcgga ttgataatca
    33481 agtaacccaa ttagcagtag agatgactaa ttttactgct tttataactt ctattttaaa
    33541 cagatttgat ttggttaaaa atcagcatac aggtacagga aaagtctatg aaattgtaag
    33601 agattaccct attacctctg tctggcttga aattgataat gataaaatga cacaggttat
    33661 cgagaatatt ttgaacaatg ccattaagta ttctccagat ggtggaaaaa ttacagtccg
    33721 tatgaaaaca acagataccc aattaattat ttcgatttca gaccaaggac taggtatccc
    33781 taaaacagat ttgcctctta tttttgatcg gttctatcgt gtagacaagg caagaagtcg
    33841 tgcccaagga gggaccggtc taggccttgc cattgctaaa gaaatcatca agcagcacca
    33901 tggctttatc tgggctaaga gtgactatgg taaaggatcg acctttacta ttgtcttgcc
    33961 ttatgaaaaa gatgcagcca tctatgaaga atgggaggaa gatgtagact aatcaatgaa
    34021 tgagagtggt tttaaatata gtattttagc atctgggtcc acaggaaatt gtttttattt
    34081 agaaacacct aaaaaacgct tattgattga tgcagggctt actggtaaga aaattaccag
    34141 tcttcttgct gaaattgacc gcaaacctga ggatttggat gctattttga ttacccatga
    34201 gcactctgac catattaagg gtgtaggcgt tatggcccgc aaataccatt tggatgtcta
    34261 tgctaatgaa aaaacatggc agctgatgga tgagtgcaat atgctaggta agcttgatgc
    34321 ctcacaaaaa catattttcc aaagggataa agttttgacc tttggagatg ttgatatcga
    34381 aagttttgga gtcagccatg acgctattga tcctcaattt tatcggatta tgaaagataa
    34441 taagtctttt gtgatgttga cagatacagg atatgtcagt gataggatga caggtattat
    34501 tgaaaatgca gatggctact tgattgaatc caatcatgat attgaaattt tgagatcagg
    34561 ctcttatcct tggagcttga agcagcgtat tttatctgat ttaggacatt tatcaaatga
    34621 agatggagcg ggagccatga ttagaagcct ggggtacaat accaaaaaaa tatacctagg
    34681 tcatctgagt aaagaaaata acatcaaaga gttagcgcat atgacgatgg tcaatcaact
    34741 ggctatggca gatttagcag taggtacaga ctttacggtc catgatacct ctccagatac
    34801 tgcttgtcca ttaactgata tttgagataa gaaactaaaa gagaatatgc aaagtagcgc
    34861 tgattggtga tataccagtc agggctattt tttgatgtct taaagcgtat tgtcttctga
    34921 gttcaatgaa ctctcattgg tcatccttta gagcatcaat agacttaaat tagcctgtag
    34981 ttttggcttg tctgatctat ttatcaaagg tgttgaggat tataaagata aggtagtttt
    35041 ttagttgttc agactaaaaa caaaatagct ctatactatc tgtagtggga ctgtagtggg
    35101 aaattcccct cagatagtgt agagtctttt gattgtatga gaaagtttcc tttgacgggt
    35161 atttaagatg tttaataaat cacgaaaaat ccacttagag tcggttttct aggtggattt
    35221 ttggtatact aaataaggtc tactgacaaa tatgaaaggg attttttatg aaacagcttg
    35281 aagagttact ctcaacatct tttgatattc aatttaatga tttgacttta ctagaaacag
    35341 cttttaccca cacctcttac gctaacgagc atcgtctcct aaacgtttca cataatgaac
    35401 gcttggaatt tttaggagac gctgttctac aattgattat ttcagagtat ttatttgcaa
    35461 agtatcctaa aaagacagaa ggagatatgt ctaagttacg ttccatgatt gtacgtgagg
    35521 aaagcttggc aggtttttca cgattttgtt cttttgacgc ttatatcaaa ctaggaaaag
    35581 gtgaggaaaa gtcaggtggt cgccgtcgtg atactatttt aggagactta tttgaagcct
    35641 ttttaggtgc tcttttatta gataagggga ttgatgcagt acgtcgcttc ttgaaacaag
    35701 tcatgattcc tcaggtggaa aaagggaatt ttgaaagggt taaagactat aaaacttgtc
    35761 ttcaagagtt tttgcaaaca aaaggtgatg tggttattga ttatcaagtc attagtgaga
    35821 aaggacctgc ccacgctaaa caatttgagg tatcgatagt tgttaatggt gctgtcctta
    35881 gtaaaggttt aggtaagtct aaaaaattag cggagcaaga tgctgctaaa aatgcccttg
    35941 cccaacttag tgaggtttag atgtttttaa aagaaattga gttggaaggg ttcaagtcct
    36001 ttgcggacaa gactaaaatt gaatttgata agggagtaac tgcagtcgta ggaccaaatg
    36061 gttcaggtaa aagtaatatt acagaaagtt tacgttgggc tttaggagaa tcaagtgcta
    36121 aaaatctgcg tgggggcaag atgccagatg tcatttttgc tgggacacaa aaccgtaatc
    36181 ctctaaacta tgctaaggta gcggttattc ttgataattc cgatcatttt ataaaaactg
    36241 ccaagaaaga aatccgtgtc gaaaggcata tttaccgaaa tggagatagt gactatctga
    36301 ttgatggtcg caaggtaagg ctccgtgata ttcatgattt gtttatggat acagggcttg
    36361 gtcgtgattc tttctccatt atttctcaag gtcgtgtaga ggaaattttc aatagtaaac
    36421 ctgaagaaag gcgcgccatt tttgaagaag cagctggtgt tttaaaatat aaaacacgta
    36481 aaaaagaaac tcagattaaa ttaaatcaaa ctcaagataa tttagaccgt ctagaggata
    36541 ttatttatga gctagacacg cagttggccc cacttgaaaa gcaagctaaa gtagctaaac
    36601 aatttttaga acttgatgcc aatcgtaagc aactacaact agatattcta gtcaaagata
    36661 ttgatatagc tcaagaaaga cagactaaag atactgaagc tttagctgct ttacaacaag
    36721 acttagcatc ttattacgct aagcgtcaat ctatggaaga agattaccaa aaattcaagc
    36781 aaaaaaagca ggttcttagt caagagtcag atcaaaccca aacaacatta ttagaattaa
    36841 ccaagctaat agctgacttg gaaaagcaaa ttgaattggt taagctagaa agtggccaag
    36901 aagcagagaa aaaggcagaa gccaaaaaac atctcgaaca gttacaagaa caattggatg
    36961 gttttcaagc agaagaaaag cagcgtacag aacaattatt gcatattgat caacaacttt
    37021 gtgatgtcaa aaaacagtta aacgaattga gcaatgcatt agagcgtttt tcaagtgatc
    37081 ccgaccaatt aatggaaact ctaagagaag agtttgtatt attgatgcaa aaagaggcgg
    37141 ccttatcaaa tcagctgaca gctttaaaag cccatttaga caaagaaaaa caggctcgtc
    37201 aacataaggc tcaagaatat cagctacttg ttactaagct tgatcaactt aatgacgagt
    37261 ctcaaaaagc tcaagctcat tataaagctc aaaaagagca agtcgaaatg ttgctccaaa
    37321 attatcaaga aggtgataaa cgcgttcagg aattagaaag agattaccaa ctgaatcaag
    37381 aaagactatt tgacttgttg gatcaaaaaa aaggaaaaga agctcgtaag gctagcttag
    37441 aatctattca aaaaagtcat agtcaattct atgcgggagt acgagctgtc cttcaatcac
    37501 aaaaaaagtt tggagggatc ataggtgcag tcagtgaaca cctttctttt gattctgatt
    37561 accaaacagc tcttgaaatt gcattaggtg ctaatagtca gcatattatt gtaacagacg
    37621 aagctgcagc aaaaagagca attgcttatt tgaaaaaaaa tcgccaagga cgagcaactt
    37681 ttttaccttt aactactata aaggctagat cattgtcaga acactatcat cgtcaattag
    37741 cgacttgtga aggttatctg ggaactgcag aatcattggt tcgctatgat gatagtcttt
    37801 cagctattat ccaaaacctt ttatctagta ctgctatctt tgaaactatt gatcaagcta
    37861 atattgcagc gcgcttatta ggatataagg taagaattgt tactcttgat ggaacagaat
    37921 tacgaccagg tggttctttt tcaggaggag ctaatagaca aagcaataca acttttatca
    37981 aaccagagtt agaacaaatc agtgaggaat taacgcgatt agttgagcaa ttaaaaataa
    38041 ctgaaaaaga agtagcttcc ttgcaaagcg atttgatagc aaaaaaagaa gaactgacac
    38101 aattgaaatt agccggtgac caggcacgct tagctgaaca aagagctcaa atggcttatc
    38161 agcaattgca agaaaaacaa gaagattcaa aggctttgtt agctgccctt gatcaaagtc
    38221 agacgactca ttctgatgaa tctttattgg cagaacaagc tcgtattgaa gaagcattaa
    38281 cagctattgc taagaaaaaa aatgccttaa cttgtgatat tgatgatatc aaagaaaaca
    38341 aagatttgat taggcaaaaa acacaaaaca ttcaccaagc tttatctcaa gctcgtttgc
    38401 aagaaagaga tttacttaat gaaaagaaat ttgagcaagc taatcaatct cgtctaagaa
    38461 ctcagctgaa gcaatgccag caaaatattc tcaaacttga aagcatacta aacaataacg
    38521 taagtcaaga cagcattcaa agactacccc agtggcaaaa acagttacaa gatgccacag
    38581 agcataagtc tggtgctcaa aaacgtttag tccaattaag atttgaaata gaggactatg
    38641 aggcccgctt agaagaaaca gcagaaaaaa taaccaaaga aagcgaaaaa aatgacacat
    38701 ttattcgtcg tcaaactaag ttagagacac atttagagca agtggctaat cgcttacgag
    38761 cctatgctaa aagtttatca gaagattttc aaatgacact agcagacgca aaggaggtaa
    38821 caaatagtat tgatcactta gaaagtgcca aagaaaaatt acaccattta caaaagacta
    38881 ttcgtgcact aggaccaatt aatagtgatg ctataactca gtatgaggaa gtgcatgagc
    38941 gtttgacttt tttaacaagt caaaagacag atctgacaaa agctaaaaat cttttgctag
    39001 agactattaa tagtatggat agcgaagtga aggctcgttt caaagtgact tttgaggcaa
    39061 ttcaaaaaag ttttaaggaa acctttactc agatgtttgg tgggggttct gctgatttgg
    39121 ttttaacgga aacagacctc ttgtctgctg gtatagagat ttctgtgcag cctcctggta
    39181 agaaaatcca atctcttaac ttgatgtcag gcggagaaaa agctttgtca gcactggctt
    39241 tattgtttgc tattatacgt gttaaaacga ttccgtttgt gattttagat gaggtagaag
    39301 cggctcttga tgaagcaaat gttaagcgct ttggggattt cctcaatcgc tttgacaaag
    39361 atagtcaatt tattgtcgtg acccatcgta aaggaacaat ggctgcagca gatagtattt
    39421 atggaattac catgcaggaa tcgggggtct ctaaaattgt atctgtaaaa ttaaaagaag
    39481 ctcaagagat gaccaattaa aaaacagaag ggagttcctt ctgttttttt ggatgttcgg
    39541 ccatatttta tgttacaata gtaaatgtaa cccctttagt taggagattt catgattaaa
    39601 ctaatagcaa cagaaatcgg aataagctaa ttgatacaat agagtacaaa gaaagccttg
    39661 gaaatagcag tttccaaggc tttttagctt tcgataggta aaagagaaaa gttgtcagag
    39721 tagatgattt tttattgaga cacccttgat tggcatttcg ttaaaaggta aagaatgatt
    39781 tcacttaatc tttgttaact aatttatcaa aatggtcagc gtaatgtaat tttaacttgt
    39841 cttcatttaa aatatcaaga acttgtatgg cttgtttcat cttttcaact ccagtttcta
    39901 attggcgctt aaattcaaag taacctgttg catagagaaa aactgtctgt tcatagaagt
    39961 ttaattcatt atctaataat gattttatct catcaattaa ataggagcaa ttagaaaatt
    40021 cctccttatt gatactaaga atgaaacaat ttatagcaag ctgagtgaca attcgtttat
    40081 tagttttgtt ccgtgaagag taaatgtaat tatttaacat ctcctttgtc aataggaagt
    40141 aggagttgta gttaattgtt cgtacacagt tacccaacaa aaggatttca tagtagcccc
    40201 atttttcaac tttaaagaga taatctgtta gttgaagtaa ttcatcatct gatggaatga
    40261 tgcttgaatc cattgtgtgt aaaatggact ttaccattgt tttctcaaaa gaattcagag
    40321 tgtaatcaga agtgtcggaa agtaaacatg ctatattatt gatattttgt gatgaatatt
    40381 gcttacgaat atactgtacc aggttagcaa atgtttcgga attggtatag tcttcatcat
    40441 gtaaaataag aaactcatcc aaagtaatgt gtaatttgtc tagaatattg atcagtcgga
    40501 tacacgatat ctctgactcc ccgcgctcaa aacgagagat ttgtgatttt gaaaggtgtt
    40561 catctgccac gaagcacaga ctaatttgct ttccttttcg aacttttcta agtgtggcac
    40621 caagttttga tttcatattt tcccactttc ccaacaaaaa tcaattccgt ttttttttat
    40681 tgtacaataa ataaaaactg aaaggaagtc cgcttatgaa gaaaatttca aaatttttgc
    40741 cgattttaat tttagcaatg gatattatca ttattgttgg tgggtaagtt acttaggtgt
    40801 acacctaagt ctttagatac tctaaagact tataggtaat ggttagctct gtgtaatgct
    40861 tgtactttat gttagtagta aactaattaa acgtaggagg atgaaattta tgtattctgc
    40921 attgcttggt aatccagttg aacattctat atcagatgaa ttatttgaat atctaaatca
    40981 caacatagga gttctggatg aatataaaca taaaaaaatt ttggtagact cagtgtgttt
    41041 agaagataaa atcaaacatc tgataaatga tccaaaatgt attggattaa atataacttt
    41101 accttataaa agagaggtaa tgaggtatat tgacaattta gacagagtag cagaga
//
LOCUS       DATTYN010000016        35097 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.16, whole genome shotgun sequence.
ACCESSION   DATTYN010000016 DATTYN010000000
VERSION     DATTYN010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35097
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.16"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..116
                     /locus_tag="VB649_001035"
     CDS             <1..116
                     /locus_tag="VB649_001035"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEP1669994.1"
                     /translation="QAQLEIFKYSETYYNPKRLHSALGYLSPVEFEKIVTH"
     gene            245..397
                     /locus_tag="VB649_001036"
                     /pseudo
     CDS             245..397
                     /locus_tag="VB649_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(444..974)
                     /locus_tag="VB649_001037"
     CDS             complement(444..974)
                     /locus_tag="VB649_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HEP1669995.1"
                     /translation="MSNFISPVYEIKSIPIEKISPNDYNPNSVAPPEMKLLYDSIKSD
                     GYTMPIVCYYDKEEDRYSIVDGFHRYRIMLDYSDIYERESGRLPVSVIDKSLDYRMAS
                     TIRHNRARGSHDVDLMSQIVKDLHECGRSDNWIAKHLGMDKDEILRLKQITGLASLFK
                     DHEFNQSWEPEELLNE"
     gene            complement(967..2301)
                     /locus_tag="VB649_001038"
     CDS             complement(967..2301)
                     /locus_tag="VB649_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HEP1669996.1"
                     /translation="MKKYLNQNVYDALIERLHFLFNEFPIVYISFSGGKDSGLLLNIL
                     LDFRDKYYPDREIGVFHQDFEAQYSLTTKYVQETFTSLEGRKKVSLYWVCLPMATRTA
                     LSSYEMFWYPWDDKTEDIWVRPMPSQDYVINLENNSITTYRYKMNQEDLAKQFGRWYK
                     QIHGNQKTVCILGNRASESLHRYSGFINKKYGYQKECWITKQFKDVWTASPLYDWSVE
                     DIWHAYYKFSYSYNELYDLFYKAGLKPSQMRVASPFQDYAVDSLNLYRIIDQETWVKL
                     LGRVQGVNFSNIYGRTKAMGYKSIALPKGHSWKSYTQFLLSTLPVRLRNNYVRKFNKS
                     IDFWHKTGGGLAEETINELIEKGYRIARNGISNYTSFKHSRVIFLDQIPDDTDDIVTT
                     KDIPSWKRMCFCILKNDHICRTMGFGLTREQQKIVAFLKEKYKTSLKELESE"
     gene            complement(2524..2823)
                     /locus_tag="VB649_001039"
     CDS             complement(2524..2823)
                     /locus_tag="VB649_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1669997.1"
                     /translation="MFLTWENLFLTNQSRRRLKLLVVERSYNNVGNFLKEYFGGFFEI
                     INFDDLRLTMVDMVSLSSEYDVIVTDMILEQTMDSEILFFNQMAPSVVANRLTDM"
     gene            complement(2980..3447)
                     /gene="perR"
                     /locus_tag="VB649_001040"
     CDS             complement(2980..3447)
                     /gene="perR"
                     /locus_tag="VB649_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEP1669998.1"
                     /translation="MDIHSHQQALDAYENVLEHLREKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPNFPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEICGKIADFMDVDVMDIAKEAHEQTGYKVTRIPVIAYGICPDCQAKDQSDF"
     gene            complement(3499..3954)
                     /locus_tag="VB649_001041"
     CDS             complement(3499..3954)
                     /locus_tag="VB649_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEP1669999.1"
                     /translation="MIYSFQNPSEDVLKAYLESAKTIAVVGLSDRKDTAAYGVAKFMQ
                     AMDYRIIPVNPKLAGQLILGEKVYASIKAIPFEVDIVDVFRRSEFLPEVARDFLAGQA
                     KVFWAQLGLENQEVQTILRSAGKEAIVMNRCLKIDYLQLVAKPECITNH"
     gene            complement(4141..6783)
                     /gene="polA"
                     /locus_tag="VB649_001042"
     CDS             complement(4141..6783)
                     /gene="polA"
                     /locus_tag="VB649_001042"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEP1670000.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPYIREMLT
                     ALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVIEISKK
                     GVAEFEEFTLAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGS
                     LEGIYEHIDGFKASKMKENLINDRDQAFLSKTLATINTASPITIGLDDIVYNGPDVAS
                     LSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSAEDIFYFETLRDNYH
                     REDIIGFAWGHGEQIYASTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVA
                     PSYDARLANYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLA
                     RKVKVLLDSKSQMLDKLTAHEQLDLYQNIELPLANVLAKMEIEGIKVNRATLQDMAEQ
                     NKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGA
                     DIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGISDFGLSNNLGITRKQAKSYI
                     DTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTM
                     EAAVDLAVPLCVDESTGQSWYEAK"
     gene            complement(6914..8641)
                     /locus_tag="VB649_001043"
     CDS             complement(6914..8641)
                     /locus_tag="VB649_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEP1670001.1"
                     /translation="METILQTKLPVAQLVEQLTEWLTKTFSGLFDIMQVVGSFLMDWM
                     TKTLLFIHPLLFIVLVTAGMFFLAKKKWPLPTFTLLGLLFIYNQGLWKQLMNTFTLVL
                     VASLISVLIGIPLGIWMAKNATVRQIVNPILDFMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLAIRDIPTELIEASDAFGSTGKQKLFKVELPLAKNTIMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGSGFVSGLALVILAIVLDRMTQLF
                     NSKPQEKAKAGKTNKWIGLAALAVFLIAALGRGIMAMTSGMADKGETVNIAYVQWDSE
                     VASTHVIAEVLKNEGYHVTLTPLDNAVMWQTVANGNADFSTSAWLPVTHGQQYQKYKS
                     KLDDLGPNLKGTKLGLAVPKYMTDVNSIEDLSKQADQKITGIEPGAGIMAAAQKTLKE
                     YHNLSSWELVAASTGAMTTSLDQAIKKKDPIVVTAWSPHWMFAKYDLKYLKDPKETFG
                     STENINTIARKGLKKDLPNVYKIIVKFHWTQKDMEAVMLDINKGMSPEAAAKKWVEAN
                     KSKVSSWTK"
     gene            complement(8657..9853)
                     /locus_tag="VB649_001044"
     CDS             complement(8657..9853)
                     /locus_tag="VB649_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEP1670002.1"
                     /translation="METILEVKHLSKIFGKKQKAALEMVKTGKNKSEIFKKTGATVGV
                     YDASFEVKKGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGKDISTMSADQLRE
                     VRRHDINMVFQSFALFPHKTILENTEFGLELRGVRKEERQRLAEKALDNSGLLDFKDQ
                     YPNQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRREMQDELLDLQDSMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEEILTNPANDFVREFVEDVDRSKVLTA
                     QNIMIKPLTTTVELDGPQVALNRMHNEEVSMLMATNRRRQLVGSLTADAAIEARKKGL
                     PLSEVIDRDVRTVSKDTIITDILPLIYDSSAPIAVTDDNNRLLGVIIRGRVIEALANI
                     SDEDLN"
     gene            complement(10341..11432)
                     /gene="ulaG"
                     /locus_tag="VB649_001045"
     CDS             complement(10341..11432)
                     /gene="ulaG"
                     /locus_tag="VB649_001045"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEP1670003.1"
                     /translation="MTKVQDITRESWILNTFPEWGTWLNEEIEQEVVPADNFAMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKQVKDMVRGHQMANMAGARKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLNHVKFVGPYECGEVWKNWGVPKD
                     RIMILKPGDSFEFKDIKITAVESFDRTCLVTLPIQGADAQDGDLAGLAITDDDMARKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYDFHPFIWEVGGKYTYPQ
                     DQNRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(11685..13331)
                     /locus_tag="VB649_001046"
     CDS             complement(11685..13331)
                     /locus_tag="VB649_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEP1670004.1"
                     /translation="MMILDKKSYDLLSYLLKLETPETVMAISHALNQSRRKVYYQLDK
                     INQALPKGVDQIISYPRLGILLTADQKAACRLLLEEVTDYNYVMKSDERRRLSSIYIA
                     VSTERVTIDKLMQINDVSRNTILNDLTELREELEDKQYKIQLHATKARGYYFGCHPMA
                     LIQYLYKLLVDVYQGGNTSFIDIFNRKLSEIQGLSVYFSKDILTYFHEYLFLSQASLG
                     KTINTQDSQFMLQILPFMLLSYRNMRLDSETKSALKQEFHLIWKRKEYHIAQDLAREL
                     YHNFKLHLDDIEVSMVAMLMLSFRKDQDHHVESQDYDDMRATISHFIDQLESRYQLHF
                     THKQDLLKQLTTHCKALVYRKAYGIFLVNPLTDHIKEKYEELFAMTQSCATILEQDWT
                     ISLTDDDIAYLTIHLGGELRHNNTEQEKTKLVIVSDDGIGIQKLLFKQCQRYLANGQI
                     EAVFTTEQYQSVYDLLAVDMIVATTDTLKTKIPMLIVNPILSDDDIIKLIRFSKQGRL
                     SEHSRFSTELTKAIEAVVKDESDRYALVSKIEKLIHRELL"
     gene            complement(13656..14360)
                     /locus_tag="VB649_001047"
     CDS             complement(13656..14360)
                     /locus_tag="VB649_001047"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEP1670005.1"
                     /translation="MAKNLQEMRERVCAANKSLPQHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDLLTPENMVVTDLDGNVVEGDLNPSSDLPTHVELYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTKTEVDGAYEQETGNVILEEFSKRGL
                     DPMAVPGIVVRNHGPFTWGKTPEQAVYHSVVLEEVARMNRLTEQINPRVEPAPRYIMD
                     KHYLRKHGPNAYYGQK"
     gene            complement(14362..15225)
                     /locus_tag="VB649_001048"
     CDS             complement(14362..15225)
                     /locus_tag="VB649_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEP1670006.1"
                     /translation="MARPIGIYEKATPKQFTWRERLQFAKDLGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGIRIPTICFSGHRRYPLGSNDSATEAKSLKLMKQCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQSCDWAEEAQVMLSIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDAGNVSAWHNDLWSEFYNGHKSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWQELFAVLKKTNYNGPFLIEMWSENCDTVEETKAAIKEAQDF
                     LYPLIEKAGLT"
     gene            complement(15230..15892)
                     /locus_tag="VB649_001049"
     CDS             complement(15230..15892)
                     /locus_tag="VB649_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEP1670007.1"
                     /translation="MTHLPNLQVALDHSDLQGAIKAAVAVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMEAALKA
                     IKEVRGDRGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KTLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAEDPAAAARAFKDEIKRI
                     WG"
     gene            complement(16001..16486)
                     /locus_tag="VB649_001050"
     CDS             complement(16001..16486)
                     /locus_tag="VB649_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP1670008.1"
                     /translation="MNLKQAFIDNNSIRLGLSADTWQEAVQLAVQPLIDSKAVTSAYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGLGVNRNAFALITLTKPVTFSDGKEVSVLLT
                     LAATDPSIHTTVAIPQIVALFELDNAIERLVACQSPKEVLEMVEESKNSPYLEGLDLD
                     S"
     gene            complement(16609..16887)
                     /locus_tag="VB649_001051"
     CDS             complement(16609..16887)
                     /locus_tag="VB649_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEP1670009.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQEVL"
     gene            complement(16958..18391)
                     /locus_tag="VB649_001052"
     CDS             complement(16958..18391)
                     /locus_tag="VB649_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEP1670010.1"
                     /translation="MEMLLAPLNWFSQNILQNPAFFVGLLVLIGYLLLKKPIYEVFAG
                     FVKATVGYLILNVGAGGLVTTFRPILVALAKKFELKAAVIDPYFGLAAANTKLEEMGF
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQFQNA
                     FGAWAVGIICGLYWAISSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLPTFLNIFHDTVVASATLMLVFFGAILAVLGPDIMSDVDLIGPGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFAFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVTVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVLV
                     CIFLLAIPQLQFAKAKDKEAYYRGEAQ"
     gene            complement(18698..21199)
                     /locus_tag="VB649_001053"
     CDS             complement(18698..21199)
                     /locus_tag="VB649_001053"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEP1670011.1"
                     /translation="MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDTITTSDQ
                     AEVVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGNEMPVWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSGFLDGLDKASA
                     IAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANVTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALD
                     KVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEAKLFSDYVKGFVQLIAPFAPHL
                     GEELWQALTASGESISYVPWPSYDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     QEVALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK"
     gene            complement(21410..22549)
                     /locus_tag="VB649_001054"
     CDS             complement(21410..22549)
                     /locus_tag="VB649_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEP1670012.1"
                     /translation="MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHL
                     YTRFSNPTTEALEDGLACLEKATYAVAYASGMAAISTVLMLLKAGDHVIFPLEVYGGT
                     CQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELVQL
                     AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYN
                     QLKLFQKNFGAIVGVEDAWLILRGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYP
                     GLDSHPNHDTHLQQAKNGGAVLSFELASKEELMTFTHRIQLPILAVSLGGVESILSHP
                     ATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF"
     gene            23033..23311
                     /locus_tag="VB649_001055"
     CDS             23033..23311
                     /locus_tag="VB649_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670013.1"
                     /translation="MKNKLFLVALATVTVLGPSLANPHHQTVHAAEQTVTQKTATETC
                     TLDGKICYGYENINEDHTDSMVQSKSQDQGFFSWLWTQITTWFSSLTN"
     gene            23454..23621
                     /locus_tag="VB649_001056"
     CDS             23454..23621
                     /locus_tag="VB649_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670014.1"
                     /translation="MKKKLSLFMIATAAVAGLSLATLGEHQTVSANDASYSNGFYGHT
                     GPDSWLLYTVW"
     gene            24033..24233
                     /locus_tag="VB649_001057"
     CDS             24033..24233
                     /locus_tag="VB649_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670015.1"
                     /translation="MKKKLSLFMIATAAVVGLSLATPENQTVSAYEVTATRDASVCWT
                     CCPLTCLKYNVEDWYKTVTSFF"
     gene            complement(24471..24866)
                     /locus_tag="VB649_001058"
     CDS             complement(24471..24866)
                     /locus_tag="VB649_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670016.1"
                     /translation="MKQQSYQPLRFVYLLVALFAALLLIARPVMADEEQTAGDRAYSQ
                     GLEKGTEEGKKAGKEATWTDLTPTVPEVSELPKDIDDSNHEHYKDGYKDGYKEGYNEG
                     WKSQHLVLTPVKVIWDLISYWLQQFFPSN"
     gene            complement(25121..26836)
                     /gene="slo"
                     /locus_tag="VB649_001059"
     CDS             complement(25121..26836)
                     /gene="slo"
                     /locus_tag="VB649_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_095889392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin streptolysin O"
                     /protein_id="HEP1670017.1"
                     /translation="MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETT
                     TTNEQPKPESSELTIEKAGQKMDDMLNSNDMIKLAPKEMPLESAEKEEKKSEDKKKSE
                     EDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP
                     VDISIIDSVTDMTYPAALQLADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVN
                     DPTYANVSTAIDNLVNQWHDNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDG
                     TLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSVTFKDLQRKGVSNEA
                     PPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAV
                     VLGGDAAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRT
                     EYVETTSTEYTSGKINLSHRGAYVAQYEILWDEINYDDKGKEVITKRRWDNNWYSKTS
                     PFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGSTLSPYG
                     SITYK"
     gene            complement(26860..27345)
                     /locus_tag="VB649_001060"
     CDS             complement(26860..27345)
                     /locus_tag="VB649_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD glycohydrolase inhibitor"
                     /protein_id="HEP1670018.1"
                     /translation="MYKVPKGLEHYQKMFQKEVTVNDLKKYLIGSDKEYRITRRDSYM
                     GDISDPEVILEYGVYPAFIKGYTQLKANIEEALLEMSNSGQALDIYQAVQTLNAENML
                     LNYYESLPFYLNRQSIVANMTKALKDAHIREAMAHYKLGEFAHYQDTMLDMVERTIET
                     F"
     gene            complement(27350..28705)
                     /gene="nga"
                     /locus_tag="VB649_001061"
     CDS             complement(27350..28705)
                     /gene="nga"
                     /locus_tag="VB649_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotine adenine dinucleotide glycohydrolase"
                     /protein_id="HEP1670019.1"
                     /translation="MRNKKVTLAHIVAKTSVAIALAGAMGSSLLANSTTYAVSGKENK
                     KSDVKYETTKVMEANATSSKEDNHVMHTLDGSMSTVWEENSPGGGVGEVLSYKFASPM
                     HIGRILIVNGDTSSKENYYKKNRIAKADVKYYNGNKLVLFQKIELGDTYTKKPHHIEI
                     DKKLDVDRIDIEVTEVHQGQNKDILALSEVTFGNIERDIFEKKFKEIKDKWVTDKQAD
                     EFIETADKYADKAVQMSAVASRAEYYRMYVSRKYHYKKEFVEKLKQVYKESGASHVTS
                     KKDLMLAFDDAKRKSTIGRQENGLFVTSFAEDMALLFTDQGKLKSADQIENIKGVDSG
                     KYSDGVYQYEYDSELTKNIDKLGYIRTASGDTPGANSLNIPGCQTWSGKHIENSESEL
                     IFPSISVKDLKSKAVLAEIDAKGYFEIIDPTIIAPNGDHKKVTGRFKIKKMQDRMQDR
                     K"
     gene            complement(29076..29615)
                     /gene="nusG"
                     /locus_tag="VB649_001062"
     CDS             complement(29076..29615)
                     /gene="nusG"
                     /locus_tag="VB649_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEP1670020.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLML
                     NMFGSETVAEVELYQIAEL"
     gene            complement(29788..30831)
                     /locus_tag="VB649_001063"
     CDS             complement(29788..30831)
                     /locus_tag="VB649_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEP1670021.1"
                     /translation="MNKKVMSLGLVSTALFTLGGCTNNSAKQTTDNSLKIAMITNQTG
                     IDDKSFNQSAWEGLQAWGKENKLEKGKGYDYFQSANESEFTTNLESAVTNGYNLVFGI
                     GFPLHDAVEKVAANNPDNHFAIVDDVIKGQKNVASITFSDHEAAYLAGVAAAKTTKTK
                     QVGFVGGMEGDVVKRFEKGFEAGVKSVDDTIKVRVAYAGSFADAAKGKTIAAAQYAEG
                     ADVIYHAAGGTGAGVFSEAKSINEKRKEEDKVWVIGVDRDQSEDGKYTTKDGKSANFV
                     LTSSIKEVGKALVKVAVKTSEGQFPGGQITTFGLKEGGVSLTTDALTQDTKKAIEAAK
                     KAIIEGTITVPEN"
     gene            complement(31158..32450)
                     /locus_tag="VB649_001064"
     CDS             complement(31158..32450)
                     /locus_tag="VB649_001064"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEP1670022.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRA
                     HVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
                     RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPEN
                     ARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI"
     gene            32889..33767
                     /locus_tag="VB649_001065"
     CDS             32889..33767
                     /locus_tag="VB649_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670023.1"
                     /translation="MIRKYDRTSTKKKSLNWIWLIIAFFMISSFIGGSSFTESLLDIL
                     PAIAIGGTGYAIFRVRSHQKRLAKAKIAKQLEDLKAKIQLADRKVRLLDTYLADHDDF
                     QYNVLAQQLLPQLSDIKAKAITLKDQLDPKIYRRITKKANDVESDITLQLETLQIATT
                     LNPQPLKTPSPNLINKAPELKPYYDNIQTDHQAILAKIQGADNQEELLALHEANMRRF
                     EDILTGYLKIKEEPKNYYNAAARLEQAKQAIQQFDEDLDETLRRLNESDLKDFDISLR
                     IMQGTTQRRTTHHQKD"
     gene            33780..35042
                     /locus_tag="VB649_001066"
     CDS             33780..35042
                     /locus_tag="VB649_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEP1670024.1"
                     /translation="MADFNFDIDQIADNAVVKTDKTTDIISDLPTDTNGQISFFEKLS
                     ADQQTAITAKAPALVDTFLADQNALLDFGQSAVEGVNATVNHILAEQKKLQIPQVDDL
                     LKSTNRELNGFIAKYKDATPVDLDKKPNFLQKLFKQSRDTLQEFYFDSQNIEQKMDSM
                     AAAVVKQEDTLARNIVSAELLIEDNTKSIEHLVGVIAFIEASQKEASQRAAALQKDLK
                     TKDSATPDYQIKTDLLARTTEVINTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGMMQQSVKSGITADAIINANNAALQMLAETSKEAIPA
                     LEQSAQNPTLSMKSVTSLAESLVAQNNGIIAAIDHGRKERAQLESAIIRSAETINDSV
                     KLRDQNIVQALLSEGKETQKTIDKTTHA"
BASE COUNT        10501 a         7526 c         6323 g        10747 t
ORIGIN      
        1 agcaagctca gcttgagatt tttaaatata gtgagactta ctataacccc aaacgtctgc
       61 attcagcttt agggtatctc tcacctgtag aatttgaaaa aatagttact cattagctta
      121 actttatgtc tatttttctt gacaagtcca gggtatgaag tccccttata cacatacttt
      181 caaaacagct ctcaatcctc tgtccgctac aaaaatacgt caccgctgcc ctccagctgc
      241 ttcattcaac gacaaacttg aagccacaaa cagactcatc aagggcatta agtacaatgc
      301 ctttagattt cagaactttg acaactttaa aaccaaaatc ctcatcgctt tgaacatcca
      361 aaaagagaga accaatctga ttctctctcg ttgttaatga taagtcaccc actacagttg
      421 acaatgagtc tcttacttcc tgtttactca tttaatagct cttctggttc ccaagattga
      481 ttaaactcat ggtccttaaa aagagaagcc aatcctgtta tttgtttcag tcttaaaatt
      541 tcatctttat ccattcctaa atgttttgca atccagttat cacttcgccc acactcatga
      601 agatccttta caatctgact catcaaatca acatcatgac ttcctctagc tctattatgt
      661 cgaatggtag aagccattcg atagtctaat gacttatcaa taacagaaac aggtaatctc
      721 ccactttccc tttcataaat atctgaataa tctagcatta tacgatatct atgaaaacca
      781 tcaacaatac tataccgatc ctcttcctta tcgtaatagc aaacaatcgg catagtataa
      841 ccatcagatt ttatactatc atacaataat ttcatttcag gcggagcaac tgaattcgga
      901 ttataatcat ttggagaaat cttttcaatt ggaattgatt taatctcata gactggacta
      961 ataaaattac tcactttcta actcctttaa actcgtctta tatttctctt ttaaaaaggc
     1021 tactattttt tgttgctctc ttgtcaaacc aaaccccata gttcgacaaa tatgatcatt
     1081 ttttaaaata cagaaacaca ttcgtttcca gcttggtata tcctttgttg ttacaatatc
     1141 gtctgtatca tcaggaattt gatctaaaaa aataaccctt gaatgtttaa aagaggtata
     1201 atttgaaata ccatttctag caatacgata tcctttttca attagttcat taattgtttc
     1261 ctccgcaagt cctccgcctg ttttatgcca aaagtctatt gatttattaa attttctaac
     1321 ataattattt cttaacctca ctggtagcgt tgataaaaga aactgagtat acgacttcca
     1381 cgaatgaccc tttggtaaag caattgattt atatcccatt gctttagtac gtccataaat
     1441 attcgaaaag ttaactcctt gaacacgtcc caaaagcttt acccaagttt cttgatctat
     1501 tattctataa agatttaggc tatcaacagc atagtcttga aaaggagatg caactctcat
     1561 ttgtgatggt tttaaacccg ctttatagaa tagatcataa agttcgttat aagaataaga
     1621 aaacttatag taagcatgcc atatgtcttc cactgaccaa tcatataagg gagatgctgt
     1681 ccagacatct ttgaattgtt tggtaatcca gcattccttt tgataaccat actttttatt
     1741 gataaaacca ctatatctgt gtaaggattc tgaagcacgg tttcctaata tacaaactgt
     1801 tttttgattt ccgtgaattt gtttatacca cctaccaaat tgtttcgcta aatcctcctg
     1861 attcatttta taacgataag tagtaattga attattttcc aaattaataa cataatcttg
     1921 agatggcatt ggtcttaccc agatatcttc tgttttgtca tcccacggat accaaaacat
     1981 ttcataacta ctaagtgcag ttctagtagc catcggtaag cacacccaat acaaagaaac
     2041 tttttttcta ccttctaaag aagtgaatgt ttcttgaaca tattttgttg ttaaactgta
     2101 ctgtgcttca aaatcttgat gaaacacacc tatttctcta tccggataat atttatctct
     2161 aaaatccagt aaaatattaa gaagtaaccc actatctttt ccacctgaga aggaaatata
     2221 gacaatagga aattcattaa acaaaaaatg taatctttct atcaatgcat cataaacatt
     2281 ttgatttaaa tactttttca ctaaacttcc tctattatgc atttaaaaat attaatacat
     2341 agattcacta agaatctctt tttcgagctt tttgtttttt aatttttcaa gttgaataat
     2401 taaaccttgc ttttcttttt caaggtaata gactctactc cttgtaagtc taacttattc
     2461 ttaatcttat ttatcgctca ttttttaaat tccgatgctc tcacagatat tatcattgtt
     2521 tagttacatg tctgtcaatc tattcgccac cacactaggg gccatctgat tgaaaaataa
     2581 aatttcggag tccattgttt gctcaagaat catatctgtc acaattacgt catactctga
     2641 agacagtgac accatatcaa ccatggtcag cctcaagtca tcaaagttga taatctcaaa
     2701 aaatcctcca aaatactctt ttaagaagtt gccaacattg ttataacttc tctcaaccac
     2761 taatagtttc aagcgacgac gcgattgatt tgtaagaaag agattttccc aggtgaggaa
     2821 caaacaaata gaggagatga ttgatggttc tttcctttaa ttccttatga tccccagcaa
     2881 ataactcttt aacataagca acaaaggtct ggtattgaac tgggggtttt tgatttgtaa
     2941 aggcactata tttataatgc ctttatttaa gggttaactc taaaaatcag attggtcttt
     3001 tgcttggcaa tccggacaaa tcccgtaagc aataactggg atacgcgtga ccttataacc
     3061 tgtttgctca tgggcttctt tggcaatatc cataacatca acatccataa agtcagcaat
     3121 cttcccacat atttcacaaa ccacattgac gtgttgatgg cccataaagt catagtaggt
     3181 ggttaaatca ttgctgattt tcaactctga gacaaaacct tcatcaacta aaactttcaa
     3241 attattatag actgtggcaa ggctcatgtt aggaaagtta ggctgtaagt cacggtaaat
     3301 cttatcggca ctagggtgtt ctgtggactg aatcatgtaa gaaataatgg ctttacgtgt
     3361 ctctgtaatt cgaatatgtt tttcccgtag atgctctagg acattttcat aggcatctag
     3421 ggcttgctga tgtgaatgaa tgtccataag ctgctactcc tatccttttt tcctttatta
     3481 tcacgcacgt ctctagtttc aatgatttgt gatgcattct ggtttagcga ctaattgcaa
     3541 atagtctatt tttaggcagc gattcatcac aatagcctct ttgcctgccg accgtaaaat
     3601 ggtttgtact tcttggtttt caaggcctaa ttgcgcccaa aagactttgg cctgacctgc
     3661 taaaaagtct ctggcaactt ctggtaaaaa ctcacttctg cgaaagacgt ctacaatgtc
     3721 aacctcaaag ggaattgcct tgatactggc atagaccttc tctcccaaaa taagctgacc
     3781 tgctaatttg ggattgactg gaatgatccg ataatccata gcctgcataa atttggcgac
     3841 accataagct gctgtgtctt tgcggtcaga aagaccaaca accgcaatgg ttttggctga
     3901 ctccaagtaa gcttttagga catcctctga gggattttga aacgaataaa tcacttgttc
     3961 ccctatctat ttaataacct ctacagctgt tcaatatagc aggataactc ctaaagcatg
     4021 gcttcaatca cttttaacct tatccgtcaa aaagctcaaa gcagcttcat gacttctcct
     4081 acaatttttt agtttattat aacataagtt gtcaaaatga gaaataacaa gtaagaaaac
     4141 ttatttggct tcgtaccagc tctgcccagt actttcatcg acacataaag gaacagctaa
     4201 atcaacagca gcttccatgg tgtctttgac aagttttttt atagcagtca actcatcatt
     4261 tggcacttcc aaaacgattt catcatgcac ttgaagcagc attttagctc taaaaccacc
     4321 tgcttgcaag gccttatcca gattaatcat agcgattttg agaatatcag ctgcgcttcc
     4381 ttgaatgggc gagttgatgg ctgtacgctc cgcaaaagag cgaacgttga aattacgaga
     4441 gttgatatcc ggtaattcac gacgacgctt aaagagggtc tctacatagc ccttgtcttt
     4501 agcctcacgc accacatttt ccatataggc tttaatccca ggatagcgtt caaaataggt
     4561 atcaatgtaa gacttggcct gtttacgggt gataccaagg ttatttgaca aaccaaaatc
     4621 agaaatccca tacacaattc caaagttaac agccttggca ttacggcggt cattggcagt
     4681 aacatctgct gccttgtcaa tcccaaacac acgcatagcc gttgaggtat gaatgtctgc
     4741 cccttcatta aaggcagcaa tcaaatgctc atcccctgaa atatgtgcca gtacccgcaa
     4801 ttcaatctgt gagtaatctg aactcaacaa gacggcatct tcatgagatg gggtaaaggc
     4861 cttacgaatc aaacgcccct gttccaaacg aatgggaatg ttttgaagat tagggtccac
     4921 actagacaaa cgccctgtct gggtgagatc ctgcacatag cgggtatgaa tcttgccatc
     4981 agccagaata taatcctgta aaccaatcac ataagtggat tgcaatttag taatctggcg
     5041 gtaatccaaa attttagcca caattggagc aatcggtgcc aaacgttcca aaacatcaac
     5101 agctgtagaa taacctgttt tggtcttctt agtcatctca agaggtagtt gcatcttctc
     5161 aaacaagata ctgcccagct gtttaggcga attaatgtta aattcttggc cagccatatc
     5221 ataaatctct tgggtgagcg cttcaataat gaccttgttt tgctctgcca tatcttgcaa
     5281 agtcgcccta ttaaccttga tcccttcaat ttccatttta gcaaggacat tagccaaagg
     5341 caattcaata ttctgataga ggtctagttg ctcatgggca gtgagcttgt ctagcatttg
     5401 agacttgcta tctaataata ctttgacctt acgagctaag tgttctagta agacgtcttt
     5461 atcaggaaca gcccgtttag cacctttacc atagactgta tcgtcttctt ccaaagagat
     5521 gtcagtaaaa atgcgggcaa tggtgctaag ctcattgtct tctacagttg acagaaggta
     5581 attagctaat ctagcatcat agctaggtgc taccaactca attcctaagt ggctcaacaa
     5641 gaccttgcta cgtttaaaat cataagtggc aatgggtttt tggaagacct gcttaaaact
     5701 atccgtcgct aataggctaa ggtcagtgga tgcgtaaatc tgctcaccat gtccccaagc
     5761 aaaaccaatg atgtcctcac gatggtaatt atcccgaagc gtttcaaagt agaagatgtc
     5821 ttctgcgcta aacaaatcag cagacacatt ggtcacttct tgataggaaa tggcagctac
     5881 tggctcttga ggcatctggc tagcaagacc tttcttgagt tgcacaaaat ccatctcatc
     5941 gtaaaattga gagaggctag caacatctgg accattgtac acaatatcat ctaagccaat
     6001 tgtgatagga gatgctgtat tgatagtggc gagcgtttta gataggaaag cttggtcacg
     6061 gtcattgatc aagttttctt tcatttttga ggccttgaat ccatcaatat gctcgtaaat
     6121 gccttccaaa ctaccaaatt catgaaggag cttaaggcct gttttttctc caatttttgt
     6181 cactccagga atgttatccg atttatctcc catcaaggct ttgaggtcaa taaactggtt
     6241 tggcgtcaag cccatttttt ccatgaggta agccagtgtg aattcttcaa attcggcaac
     6301 ccctttttta gaaatttcaa tcacggtatt ttcgtcagtt aactggatca aatctttatc
     6361 accactgaca atggtcacat caaaaggcac ttctgtgcgc tccgccattt tatcaagcgt
     6421 cccgataata tcgtctgctt cgtagtgttc caactcataa taagcaatcc caagggctgt
     6481 caacatctca cgaatataag gaaactgctc acgaaattca tctggggttt tagcgcgacc
     6541 cgccttataa tcggcataca tttctgttcg gaaggtggtt ttgcccgcat caaaagccac
     6601 cagcacgtga gtaggctgga ctcttttcat catgtggtct agcatcaaat gaaagccata
     6661 aatggcattg gtatgaagac cgctatgatt tttaaagcgg tcaatttgat tgtagagggc
     6721 aaaaaaggca cgaaaggcaa cagatgagcc atcaattaat agtaatttat tcttgttttc
     6781 catagcctta ttataacaca gagggacagg cttttctcct ttaagccatt ggttttgctg
     6841 ataagtaaat agttaaccta aaaagcctag gaaaattcct agacttctct atttgctatt
     6901 tagacaaaag cacttatttt gtccaacttg atactttaga tttgttagcc tctacccatt
     6961 ttttggcggc agcttctggg ctcatgcctt tattgatgtc aagcatgact gcttccatat
     7021 ctttttgggt ccagtggaac ttaacaatga ttttgtagac atttggaaga tcttttttca
     7081 agcctttacg agcaatggta ttgatgttct cagtcgagcc aaaggtttct ttaggatctt
     7141 taaggtactt caagtcatac ttggcaaaca tccagtgtgg tgaccaagct gtcacgacaa
     7201 taggatcttt tttcttgatc gcttgatcca aggaagtcgt catggctcct gttgatgccg
     7261 ccactaactc ccaactagat agattatgat actcttttag agtcttttgg gctgctgcca
     7321 tgatacctgc acctggttcg atccctgtga ttttttgatc ggcttgtttg cttaagtcct
     7381 caatactatt aacatctgtc atgtattttg gaacagctaa accaagtttg gtccctttta
     7441 ggttaggtcc taaatcatct aattttgact tgtatttctg atactgttgc ccatgagtta
     7501 ctggcaacca agcactagtt gaaaaatcag cgttcccatt tgcaacggtt tgccacataa
     7561 cggcattgtc aagcggagtc aaggtcacat ggtaaccttc gtttttcaaa acttctgcaa
     7621 tcacatgagt tgaggcaacc tcagaatccc actgcacgta agcgatgtta acagtttcac
     7681 ccttatctgc cataccagaa gtcatagcca taataccgcg tcctaaagca gctatcaaaa
     7741 agacagcaag ggctgctaga ccaatccatt tattggtttt gccagctttg gctttttctt
     7801 gaggtttgct attgaacaac tgtgtcatac ggtcaagcac aatcgccaag ataaccaagg
     7861 caagaccact gacaaatcca ctaccaatat cagcgtgttg aagggctgac aagacttcac
     7921 gtcctaaacc aggagcacca atcatggaac ctgttactac catggaaagg gctaacatca
     7981 tggtctgatt aacacctgcc ataatagtat ttttagctaa aggcaattcc actttaaaga
     8041 gcttttgttt cccagttgac ccaaaggcat ctgaggcctc aatcaattct gttggaatgt
     8101 cacgaatggc caaatttgta aaacgaactg ttgggggcaa ggcaaagatg actgaagcaa
     8161 atactccagg caccatacca ataccaaaaa aggcaacggc aggaatcaag taaacaaaag
     8221 ccggcatggt ttgcataaag tccaaaatag gattcacaat ctgacggaca gtggcatttt
     8281 tagccatcca aatccccagc ggaataccaa taagtaccga aatcaaacta gctactaaca
     8341 ccagagtaaa ggtattcatt agctgcttcc ataacccttg attgtaaata aagagcaatc
     8401 ctaacaaggt aaaggttggc aaaggccatt ttttcttagc aaggaaaaac atccctgctg
     8461 ttactagaac aataaaaagt aacgggtgga taaataaaag tgttttggtc atccaatcca
     8521 tcaaaaagct accaactact tgcataatat caaatagacc tgagaaagtt ttagttagcc
     8581 actccgttag ctgctccacc agttgagcta ctggtaattt tgtttgtaat atcgtttcca
     8641 aaatgcatca ctccttttag ttaaggtctt cgtctgagat attagccaag gcttcaatca
     8701 ctcgtcctcg aataatgaca cctaacagac gattattatc atctgtcact gcaatcggag
     8761 cagatgaatc atagataaga ggcaaaatat ctgtaataat agtatctttt gagacagttc
     8821 tcacatcgcg atcaatcact tctgatagcg gtaacccttt tttgcgcgcc tctatagcgg
     8881 catcggccgt caaactaccg actaattggc ggcggcgatt cgtcgccatc aacatagaca
     8941 cctcttcgtt gtgcatacgg ttcaaggcaa cttgaggtcc atctaattca acagtagttg
     9001 ttaacggttt gatcatgata ttttgtgctg tcaagacttt agaacggtcc acatcctcaa
     9061 cgaattcacg cacaaagtca ttggctgggt tagtcaagat ttcctcacca gtaccaattt
     9121 gcataatttg tccgtctttc atcaaagcaa tccgatcacc aatacgcaaa gcttcattca
     9181 agtcatgact gataaagatg atggtttgtt tcatgctatc ttgcaaatca agtaattcat
     9241 cttgcatctc acgacgaatc aaaggatcaa gcgctgagaa tgcctcatcc attaagagaa
     9301 ttttaggact attagctagc gcacgggcta ggccgacacg ctgctgcatc ccaccagata
     9361 gttggtttgg gtactggtct ttaaaatcta ataggcctga attatcaagg gctttttctg
     9421 ccaatcgctg gcgttcttct ttgcgaacgc cacgtaattc caaaccaaat tcggtatttt
     9481 ccaaaatggt tttatgagga aagagggcaa agctttggaa aaccatgtta atgtcatgcc
     9541 ggcgcacctc acgcagctga tctgctgaca tggttgagat gtctttacct tccagcaaga
     9601 tagatcctgc tgaaggttca atcaaacgat ttagcatgcg gacaagggtt gatttcccac
     9661 ttcctgatag ccccataata acaaagattt cacctttttt gacctcaaaa ctagcgtcat
     9721 agacacctac agtagcgcct gttttcttaa aaatctcact cttatttttg ccagtcttta
     9781 ccatctcaag agctgctttt tgttttttgc caaaaatttt actgagatgt ttgacttcta
     9841 aaattgtttc cattcgtttt ttctcctagg taatcgttta tcatgtgaaa tagtgacata
     9901 gctttggcga aatattagcc aatatttaac aaagtagctc tacacaatta ataaacgtgt
     9961 ggtcactttt ttacttaaaa aaagaatctg ccgaaacaga acataactat attatcacgt
    10021 gtggtcactt tttgtcaagg acaataactc gatctggtaa tgccacaatg ataggtgatc
    10081 gctttcattc ttttagatat ggtcttttaa ccagtacaat tttttatcac aactgatgac
    10141 tatttctttg ctgattaggc tattgttaca ttagaaatcc ttcttttacc tataatatct
    10201 cttttgcggc catcgtaaat aacgaccacg gtgactctta aacatttgct catctctcca
    10261 aaaaaactca cctaagacag tatcctatga agcgagttag cttaatcagg cactatcatc
    10321 ttaggtgagt agggtgttgc ttatagtaaa gctttaaatt ggatattaga atcttctaag
    10381 aagcagtcat caaatccacg aggatgatgg tattcgatac gattttggtc ttgtggatag
    10441 gtgtacttgc caccaacctc ccagataaag ggatggaaat cgtattggag acgttctttg
    10501 cgcattttcc acagttcaag gatttcatct gttgatgcca taaagtttga ccaaatgtca
    10561 taatgaactg ggataacgac tttagcacgg agattttctg ccatacgaag aaggtcaaca
    10621 gaagtcatct tgtcttgaat cccaattggg ttttccccat agttatttaa cacaacgtca
    10681 atatcataat cacgtccatg tttagcaaag tagttcgaaa aatgagaatc cgcaccgtga
    10741 tagatggtac cacctggtgt ttcaaaaata tagttaacag ctttgcgagc catgtcatca
    10801 tctgtgatag ctaaacctgc taaatcacca tcttgagcat cagctccttg tattgggaga
    10861 gttaccagac aggtgcggtc aaacgactct acagcggtga tcttaatatc tttgaattca
    10921 aagctatcac ctggctttaa gatcataata cgatcttttg gcacacccca atttttccaa
    10981 acttcaccac attcataagg tcctacaaat ttaacatgat taagttttgg gttattgata
    11041 atggctgccg cagtattgat atcgatgtgg tcactatgat aatgagaaac caaataataa
    11101 tccaactcat taatcataaa tggatcaatc accattggtt gggccctaag attgggctgt
    11161 aatttacgag ctcctgccat attagccatt tgatgtccac gaaccatatc cttaacttgc
    11221 ttggtcgctt tcccacgatt tgaccataag tccatgacaa cattagcacc gcctggtgtc
    11281 ttaatccaga taccacagtt tcctaaccac cacatcgcaa agttgtcagc tggcacgact
    11341 tcttgctcaa tttcttcatt taaccatgtt ccccattctg gaaacgtgtt aaggatccat
    11401 gattcacgtg taatatcttg tactttagtc attagggttt cctccgaatt tgttcttcgt
    11461 ttctatactt taagtataga ctttcttgtc aatgataaaa agaccaagtg tcacacagat
    11521 ctgtgttcaa aagtggactg actttttcat tagctcagtc taatactgtc tcattttgca
    11581 cactgtatct cgcatcaata ctgtattcaa agctatatta aaaacctcag ttatattttt
    11641 ctatgtcata gaaaactgag gtactttgac gacttaacac ttactcatag cagctcgcga
    11701 tgaatgagtt tttcaatttt agaaaccaag gcataacgat ctgattcatc ttttacaaca
    11761 gcttcaatag cttttgtgag ctctgtagaa aagcgggaat gctcactcaa gcgtccttgc
    11821 tttgaaaagc gtatcaattt gatgatatca tcgtcactta aaatagggtt aacaataagc
    11881 atcgggattt tagtctttag cgtatctgta gtagcaacaa tcatatcgac tgctaaaaga
    11941 tcgtaaacac tctgatactg ttctgtcgta aaaacagctt caatctgacc atttgctaga
    12001 tacctttgac actgtttgaa caataacttt tgaatgccta tcccatcatc tgaaacaata
    12061 acgagtttgg tcttttcttg ctctgtatta ttgtgacgca gctctccccc gagatggata
    12121 gtcaagtagg caatatcatc gtctgtcaag ctaatcgtcc aatcttgttc caaaatagtg
    12181 gcacaagatt gagtcatagc aaacaattct tcgtattttt ctttaatatg gtctgttaag
    12241 ggattaacta aaaaaatccc ataagcttta cggtaaacga gcgccttaca gtgggtcgtc
    12301 aactgcttca gcaaatcctg tttatgcgtg aaatgtaact gataacggct ctccaactgg
    12361 tcaataaagt gactaatggt tgctcgcatg tcatcataat cttgactttc cacgtgatga
    12421 tcttgatctt ttcgaaaaga caacatcaac atcgctacca tactaacttc gatatcatcc
    12481 aaatgaagct taaaattatg gtaaagctct ctagctaagt cctgagcaat gtgatattct
    12541 ttacgtttcc aaatcaaatg aaattcttgt ttaagagcag actttgtttc tgaatcaaga
    12601 cgcatattac gataacttaa aagcatgaaa ggtaaaatct gcaacatgaa ttggctatct
    12661 tgggtattaa ttgtctttcc taaactagct tgagataaaa agagatactc atgaaaatag
    12721 gtcaaaatat ctttagaaaa ataaaccgat aagccttgta tctctgagag tttacggttg
    12781 aatatatcaa taaagctagt attgccacct tggtaaacgt ccactaacaa tttgtacagg
    12841 tattgaataa gagccattgg atgacaacca aaataatatc ccctagcctt tgtcgcatga
    12901 agctgaatct tgtattgttt gtcttccagt tcctccctta actcagtcag gtcatttaaa
    12961 atcgtgttac gagacacatc attgatctgc atcagtttat caatggtcac gcgctcagtg
    13021 gaaaccgcaa tataaatcga ggataggcgt ctgcgctcat cacttttcat gacataatta
    13081 taatcagtca cttcttctaa taataagcga caagcagctt tttgatccgc cgttaaaaga
    13141 atgccaagtc taggataaga gataatctga tctactccct ttggcaaagc ctgattaatt
    13201 ttgtcaagct ggtaataaac tttacgacgt gactgattta aagcatgaga aatggccata
    13261 actgtctcag gtgtttctag tttaagtaaa taagacagca agtcataact ctttttatct
    13321 aaaatcatca tgtttacaaa cctcctctct gaaaatccat ccttgcttat tttatcatga
    13381 tttcagtgac tgcgcagcca agttttgaaa aactcaccat aataagattc gcttaatatg
    13441 attcgagcta atcacctcaa ctgatccaac accaacacct tatatctggt ctctaagaac
    13501 tccacaacat acgattcatc cagtttgtgc tcattggcgt ttaaacagtt catcgaaaag
    13561 gacaagtcaa aaggacttgc ccaaacaatg attaacaaaa ccttgaactt tttggcttct
    13621 agtgagaacc tgtgctaata agccatatcg tgacctcatt tttgaccgta ataagcattt
    13681 gggccatgtt tacgcaaata atgcttatcc ataatgtatc ttggcgctgg ctctacgcgt
    13741 ggattgattt gttctgtcaa gcgattcatc ctagccactt cttctaagac aactgagtgg
    13801 taaacggctt gctctggggt tttcccccac gtaaatgggc catgattgcg aaccacgatt
    13861 cctggaaccg ccatcgggtc aagacctcgc ttgctaaact cttctaaaat cacgttgcca
    13921 gtttcttgct cgtaagcccc atcaacttct gtttttgtga gagaacgagc acacggaact
    13981 ggtccataga agtagtcagc atgcgtagtc ccataaaacg gaatatcacg acctgcctga
    14041 gcccaaccaa cagcttctgt tgaatgagtg tggacaatac cgcccacttc tggccaagct
    14101 ttataaagtt ccacatgggt tggcagatct gaagaagggt tcaaatcacc ttcgaccaca
    14161 ttcccatcaa ggtctgtaac aaccatattt tctggtgtca agaggtcgta gtccacccca
    14221 gaaggcttga tgacaatacg tcctaattca cgacaaactt cagagacatt gccccacgta
    14281 aatttgacaa gaccgtgttg tggtagagac ttgttagccg cacagacacg ttcacgcatt
    14341 tcttgcaagt ttttcgccat attatgtcaa ccccgctttc tcaataagtg ggtaaaggaa
    14401 gtcctgagct tctttgatag cagcttttgt ttcctccacc gtgtcacaat tttctgacca
    14461 catttcaatc aaaaaaggcc cattgtagtt ggttttcttg aggaccgcaa acagctcttg
    14521 ccagtccaca caaccttgac caaatggcac atcacgaaac tgcccttttg aggtttccgt
    14581 gacagcataa gtatctttca agtggagggc tgcaatggat ttgtgcccat tgtaaaattc
    14641 actccacaaa tcattatgcc aggcagaaac attgcctgca tcaggataaa caaagagata
    14701 aggcgagtca atctcttttt caactgccaa gtatttttca atagagttga taaaagggtc
    14761 atccataatc tcaatagaaa gcatcacttg ggcttcttcg gcccagtcac aagattgtct
    14821 caagtttttg ataaaacgag cacgggtttc aggcgatttt tcttcatagt aaacgtcata
    14881 accagctaat tgaatggtac gaacgcctaa gtcctgtgcc aattcaatac attgtttcat
    14941 cagtttaaga gacttggctt cagtagcaga atcatttgag cctagtgggt aacgtctatg
    15001 accagaaaaa caaatggtcg ggatgcgaat gcctgtttca taaatggctt tcactaaatc
    15061 aagccgttct tccttagtcc actctaagcg cgctaagcga gcatctgatt catcaacaga
    15121 catttccaca aagtcaaaac ctaagtcttt tgcaaattgc aagcgttcac gccaggtaaa
    15181 ctgttttggc gttgcttttt cataaatacc aataggacgc gccataaagt tacccccaga
    15241 tacgtttgat ttcatctttg aaggcacgcg ccgctgcagc aggatcttct gcttcagtaa
    15301 tgcctcgccc tgcgataaag gtaaagacat ccaccccttc aaaaagtttc aaagtgtcta
    15361 catcaagccc accagttact gagacacgaa agcccatgtc aatcaatgtt ttcaccttgt
    15421 taaggtcttt ttcaccccaa gtttctccag caagaagggc atcacgagat tggtggtaaa
    15481 tcgcttggga aatcccagcg tcaagccata attgagcttg ttcataagtc caatcaccat
    15541 aaagttcaat ttgaatctcc ccacggtctc cgcgcacttc ttttatggct ttgagggctg
    15601 cttccatggt tggaatcgtc gcacagcaaa tgcaggtcat ccagtcagca ccacgttttg
    15661 cattgttttt agcgaccgta ccgccagcgt cagcacattt ggtatctgct acgataattt
    15721 tctctgggaa gaggctgcgt aatacctcaa ctagttcgct tcccacttga agcaaacaaa
    15781 cggtaccagc ttcaatcaca tctacttcgt gacccacagc aacggctgct ttgatagccc
    15841 cctgcaagtc agaatggtct aaggcaactt gtaaatttgg aagatgtgtc atgtgttttt
    15901 cctagaactc tcagcggcta tgaaaaagct gatgaggagt tcttatcctt tcaataatga
    15961 ttgtgagtcg ttttatccgt ttaagtcagt aagctatcga ttaagagtct aaatccaaac
    16021 cttctaaata cgggctattt tttgattctt ctaccatttc tagaacctct ttaggacttt
    16081 ggcaagccac caagcgttca atggcgttat ctagttcaaa caaggccaca atttgtggga
    16141 tagccactgt tgtgtgaata gaagggtctg tagcggccaa cgtcaaaaga acagaaacct
    16201 ctttaccatc tgagaaggta actggttttg ttagtgtaat caaagcaaat gcattgcgat
    16261 taacgcctaa acctgcttct gcatggggca tagccatacc tggcatcaac acataataag
    16321 ggccgtattt ttctgttgat gcaatgatgg cgtcgtagta agctgacgtc actgctttgc
    16381 tatcaatcaa aggttgaaca gctaattgaa cagcctcttg ccaagtatca gcacttagcc
    16441 ccaatcggat ggagttgttg tcaataaagg cttgttttaa attcataaaa actatctctt
    16501 tctagtgtct tgctttgcaa cacacaccat ttttactagt tttatcctac taaagagaaa
    16561 gagctgaaaa ccttcgtcac aactccttcg ttttgattca gaattagctt atagcacttc
    16621 ttgtagtttg gttttaattt cattatcatc catcaggtta tcaagaccaa ctaagtggcc
    16681 tttggtacga ccatcaagct catgaatcaa gtggtttgat gccactacaa tatcataacc
    16741 agaagctaga cctttagctt caccaactga gcaagaagct gactgaatat ctgtcacacc
    16801 aagttgacga agcgcatttt caactttcat tttgatcacc atagatgacc ccataccatt
    16861 gccacatgct gttaagactt taaccattgt tttttcctcc gaaaatgttt tattattgtt
    16921 ttgttaaaat agcagagcta tttcttaaga tgcagtgtta ttgagcttcc ccacggtagt
    16981 aagcttcttt gtccttagct tttgcgaatt gcaattgtgg aatggcaagt aagaagatgc
    17041 atacaagcac ataccctgca ataccaagga atttgaagag gtacccaaat ggtaaccatg
    17101 gaagaaccaa gtcgatatta ccgtgataac cacctgtaag tcctaaaaga cctacagtaa
    17161 cagcaccaag tgcaacttgc aaaatacctg agataaatga tagagctacc gctgctttcc
    17221 agccaccacg tttatctgca taaaccgcaa ttgccgcatt atcaaagaat acgggaacga
    17281 atcctgtgat aattaagatt ggatttttaa agataacaag aagagcaatg gtgattaatt
    17341 gaccaatcaa accaaaggca aatcctgaaa gcaccgcatt tgaagaacca aagccatagg
    17401 aagctgcaac gtcaaccgct gggaatgacc ctggaagcaa tttgcttgag atgccttgaa
    17461 aggcattggt caattcagaa acaaacatgc gaacaccctg catcaagata aagagataaa
    17521 ctgagaaggt gagagaggtt tgcaaaatat acatgaagaa agcttgctta gctgggttga
    17581 atgctccagg tccgattaag tccacatcag acataatgtc tggaccaagg acagccaaga
    17641 tagctccgaa aaagaccaac atcaaagttg ctgacgcaac aacagtatca tggaaaatgt
    17701 ttaagaaggt tggtaatttt aggttatcaa ggttttcttc ttttttacca aagaacggtg
    17761 caaccttatc cacaaaccaa atcgcaaatt gttgttggtg accaatcgca aacccaccgc
    17821 cacctgtaag gcgttgagtt gcttcaacgg tcatgtttga gctgatagcc cagtaaagcc
    17881 cacagatgat accgactgcc catgccccaa aagcattttg gaattgaggg attaaaagaa
    17941 ggacaaagac cgaaatcgtc gctgcctgtt ggaccatgat gtgacctgtg atgaaaaggg
    18001 tacgaacttt agtgaccttg cgaagtgcaa ccaaaagaat gttgacccca aatccaatca
    18061 agagagctgt cgtagcaaca ctgatgaagc ccatctcttc taacttagta ttagcagcag
    18121 ccaaaccaaa ataaggatca ataacggcgg ctttcaattc aaatttctta gcaagagcaa
    18181 ccaagatcgg acgaaaagtc gttacaagac cgcctgctcc aacgttcaaa atcaagtaac
    18241 caacggtagc ctttacaaaa ccagcaaaga cttcataaat gggtttttta aggagtaaat
    18301 acccgattaa aaccaaaaga cctacaaaga acgctgggtt ttgcaaaata ttttgcgaga
    18361 accagtttag gggagctagg agcatttcca taagaactac ctcttttcaa agttaataaa
    18421 gataaagtgt ttatatgttc attataggta atgaaagcgt tttaaaaaag accaactatc
    18481 acacaaagaa gtgttcaata ttagacttaa gttaacttat tttaaaattt aactacactt
    18541 aataataagg agaaaatatc cctaaacaac gattaaaaac cacaagaacg aaggttcttg
    18601 tggtttttct agataaattg ctttttgaat agatcagctc tttggcatta actgtgacgt
    18661 gacgcaaata accattgaag ggctgtgtca cctcaaacta tttgataaca atattaacga
    18721 gtttgtttgg tactgcgatg actttgatga tgtctttgcc tgcgatttcg gcttggactt
    18781 tttcgttagc aagagcaact tcttgtaatt cttcgcgtga aaggtcttta gcaacgacaa
    18841 gtttagcttt gaccttacct ttgatttgga caacgatttc cacatcgttt tcaaccaatt
    18901 tgctttcatc ataacttggc catggcacgt aagagattga ctcacctgag gctgtcaagg
    18961 cttgccagag ttcctcacct aagtgcggtg caaatggtgc aatcaattga acaaagcctt
    19021 tgacatagtc gctaaagagt ttggcttcct tgttggctgc gttgacaaag accatgagtt
    19081 gagcgatagc tgtgttgaat ttcatttggt caacttgctc agtaacagcc ttaacagttt
    19141 cgttgtaaac cttgtcaagg gctccgctat tttcttcagt aatctcttta gtcgtgatca
    19201 aacggtaaac acggtccaag aacttacgtg agccttcaag accttcttca gaccaagcga
    19261 tggaagcatc aagtggtccc atgaacatct cgtaaacacg aagggtgtca gcaccgtact
    19321 gctcaacaac atcatctggg ttgacaacgt tcttaagtga tttagacatc ttagctggtg
    19381 cttgttccag ctcttcacca gtttccacat ggaagaagct gccatcacgt ttttcaacct
    19441 tgtcagtcgc tacaagcgct ccacggctgt cgcggtagct tgttcccaaa atcatccctt
    19501 ggttaaagag tttttggaat ggctctttgg ttggtacaac accgagatcg taaagaacct
    19561 tgtgccagaa gcgagcgtag agaaggtgaa gcacggcatg ctctgcacca ccgacataga
    19621 tatcaactgg caaccattgt ttgaggagtt cctcgtcagc cagtttttca gtgttgtgtg
    19681 gatcgatgta acgaagataa taccagcttg aacctgccca ttgtggcata gtgttagtct
    19741 cacgacgacc tttcacacca tcttcacgag tcacttccaa ccagtctgtc acgttagcaa
    19801 gtgggctctc accagtacct gaaggacgga tatccttcgt tactggaaga accagtggca
    19861 actcactctc aggaaccgct gttgaggtcc catcttccca gtggatgatt gggattggct
    19921 caccccaata acgttgacgg ctaaagagcc agtcacgaag acggtaagtg actttctcat
    19981 taccgacgcc ttctgcttca agccattcga ccattttggc aatagctgac gctttgtcaa
    20041 gaccatctag gaagcctgag ttgatgtgaa gaccgtcttc tgtaaaggca gcctcttcaa
    20101 cattaccacc ttcaagaaca gggatgatgt ctaggttaaa ttgttttgcg aattcccagt
    20161 cacgttcatc gtgggctgga acagccatga tagcaccagt accgtagctg gcaaggacat
    20221 agtccgcaat ccaaactggc atttcgttac cattaactgg gttaatcgca tagctacccg
    20281 tccaaacacc tgttttttct ttggcaaggt ctgtacgagc aaggtctgat ttgagacttg
    20341 cttgacgttt gtagtcagcc acgacttctg cctggtcaga tgtcgtaata gtatcaacca
    20401 aggcatgctc aggagcaaga acggcataag ttgcaccaaa aagggtgtca ggacgtgttg
    20461 taaagacagt gaagtcctta tctgtatcct taaccttgaa ggttacattg gcaccagttg
    20521 atttaccaat ccagttgcgt tgcatgtcct tgattgattc tggccagtca acttcttcca
    20581 agtcttccag caagcgctct gcataggcag tgattttgag catccattgg cgcataggtt
    20641 ttctgacaac tgggtagccg ccacgttctg atgtcccatc tggaagaacc tcttcgttgg
    20701 cgatagctgt tcccaattct tcaacccagt taacgggaac ttcagcttcg taggctagac
    20761 ctttttcata aagcttggta aagatccact gtgtccactt gtagtagtta gggtcagttg
    20821 tgttaacttc acgatcccag tcgtatgaga aaccaagagc attaatctgg cgtttgaagt
    20881 tagcgatgtt ttcagctgta aactcggctg ggtcattacc agtatccata gcgtattgct
    20941 cagcaggaag tccaaaggca tcccaaccca ttgggtggag gacattgtga ccttgggcac
    21001 gtttgaaacg gctgagaata tcagttgctg tatagccttc tgggtgacca acgtggagac
    21061 cagctcctga tgggtatggg aacatatcta gggcataaaa cttaggtttt gatgcgtctg
    21121 ttcctgtttt aaaggtgtga ttatctgccc aaaaggcttg ccatttgggt tcaatagcgg
    21181 tgtgatcgta aaatgtcatg tgaaatctcc catgtaaaaa atctagtctt cttattatag
    21241 catgagatga agcttttagg aatggtcaag acatgactag caccttggct tttgagactt
    21301 cagacgatta gctattttta aaccctgctt tagcatcaac catcctcaca aaaagctaat
    21361 aaaaaagcca gacttgctct gtaaacagag ccaatctgga caagtagact taaaaagcaa
    21421 gtgcttgctc aaaatcggcc aataaatctt cgatattttc aacaccacaa gacaagcgca
    21481 gcaaaccatc aacaacccct tgttccaacc gcgcttgtga cgataaacaa gcatgagaca
    21541 tcgttgctgg atgtgacaaa atggactcta ctccacctag actaacggct aaaatcggca
    21601 actgaatacg atgggtaaag gtcatcagct cctccttaga agccaactca aaggataaaa
    21661 cagcaccacc attcttagct tgttgcaggt gggtatcgtg attaggatga ctgtctaagc
    21721 cagggtaatg taccttaaga actttggggt gcttcgctaa atagttagcg agctgctgag
    21781 cattttttac cgcttgttcc atacggatcc ccatagtttt catgccacga agaatcagcc
    21841 aagcgtcttc gaccccaaca attgctccaa agtttttttg aaaaagcttg agctggttgt
    21901 agatagcctc attattggta gcagctaaac cagctaccac atcactatga ccattgataa
    21961 atttggtcac actttctacc acaatatcca cacccatagc taagggttct tgatacaaac
    22021 tggtcataaa ggtattatca gccacagtta gcacaccata agctttggcg agttgcacaa
    22081 gctctgaaat atcgcaaatt ttcaagagcg gatttgacgg tgtctctaga taaatcatac
    22141 gcgtattagg cctgatactt gcttttactg ttgctaaatc agccatatct acaaagcttg
    22201 tttcaatctg ataattgggt aaaatagctg tcgcaaattg acaagtccct ccatagacct
    22261 ccaatgggaa aatcacatga tctccagctt ttaagagcat caaaacagtt gaaatagcag
    22321 ccataccaga tgcataagcc accgcataag tcgctttttc taaacaggct aacccgtctt
    22381 ctaaagcttc agtcgttggg tttgaaaagc gtgtgtacaa atgtttttga ctaggacaat
    22441 acagttctga attgtggaac gtcgaagtct gatagatggg aactgaagct gctcctgtaa
    22501 actcgtcaat aaccgtatag ccatgtaata aggtcgtatt ttctctcatt tcgtgcacct
    22561 ccgcaatagc gttaactcca atgaactctc ttttagacaa tggtcccacc ccaatggtta
    22621 cacaaaccaa aaagctcttc aaaaaagcgt gatctgctaa cctataagaa aagtagtggg
    22681 caccttttaa atggataatg aatttttcca acaatatcat ttttagatcg attacgttta
    22741 ttatacaacc tttagctaag tttgcaagcc cttttatcat ctttgaccaa gctgccaaca
    22801 cctctccagc aagttaaagt atggctacct ttggccccat cgtctcaaaa gctcagatta
    22861 tcacactgac agtcctacct tgcatcgtca cctactcaat acggcaatat tgccatcaca
    22921 atttcattaa aaggtcacaa tttatttcat ttaatgagaa acagaacttg ttttcaccat
    22981 gcgtcttata gtacactgct aaagtactat ttatttttag gagagaaata tagtgaaaaa
    23041 caaattattt ttagttgccc ttgcgaccgt aactgtccta gggccgtctt tagcaaaccc
    23101 tcatcaccag accgtgcatg cggctgagca gacagtaact caaaaaacag ctactgaaac
    23161 atgtacatta gatggaaaaa tatgctacgg ttatgaaaat atcaatgaag accacaccga
    23221 tagcatggtt caatctaagt ctcaagatca aggtttcttc agttggcttt ggacacaaat
    23281 aacaacttgg ttttcttcat taacgaacta aaaccatctc gtggcggttt tctaatccta
    23341 ggtcgccaca tttcttattc agataaataa taataaaaac attaaaataa cacttgattt
    23401 attaacaaaa agttagtata atatagtcat actacaaatt aaaggagtta tctatgaaaa
    23461 agaaattatc tttatttatg atcgcgactg ctgctgttgc aggccttagc cttgcaacac
    23521 taggagagca ccaaactgtt tcagcaaatg atgctagcta cagtaacggt ttctacggac
    23581 acactggtcc tgacagctgg ttactttaca ctgtatggta aacctcatac cgtaacatag
    23641 aagctatctt cttcgtaaga ctacggttat gaaaagccta ggactgcata agcagcccta
    23701 ggctttttga ttggctaaaa tgtttttgct aatagctcct caaggtaaaa cagaaaaggc
    23761 acactgccta taaaaggaga ggagcccaaa acacaagtcg taacagttgc tagccaacca
    23821 gcaccaaaaa agctgtaata acttaaatag aatgataaac agattaatat aattagtaat
    23881 taatgtgatt tgtataagat aaagaaatgc tttagtcttg gctttctttg cctttttcag
    23941 tcaaacatat cacaaaaaga ttaaaatgtg atattgaatc attaatagaa tatgagtata
    24001 atgtagatat actataattt aaggagttac aaatgaaaaa gaaattatct ttatttatga
    24061 tcgcaactgc tgctgttgta ggccttagcc ttgcaacacc agaaaaccaa actgtttcag
    24121 catacgaagt gaccgcaact agagatgcca gcgtgtgttg gacttgttgc cctctaacct
    24181 gcttaaagta taatgtagaa gactggtaca aaacagtaac aagtttcttc taatttcaaa
    24241 cagctttaag taaaatcaac atagtctgag acagtagtct cttgattatg ctaaaaaaag
    24301 caatggcgtc aaagctattg ctttttttgt gtggccgaga gactttttca caaactcttt
    24361 ttttattgtt cattcccata tctaaaaaaa aacagccttt cacattatag cagtcaaagg
    24421 ctgtttttaa ttcgttttta ttatgacatg ctttgtgctg cggtacttga ctagttactg
    24481 gggaagaatt gctgtagcca ataagagatc aaatcccata taaccttgac cggagtcaag
    24541 acgagatgtt gagatttcca gccttcatta taaccctctt tgtacccatc tttataacca
    24601 tctttataat gctcatgatt agagtcatca atatccttag gtaattctga tacttcaggg
    24661 acagttggag tcaaatcagt ccaagtagct tcttttccag cttttttccc ttcttctgta
    24721 cctttttcta aaccttgact ataagctcta tccccagcag tttgctcctc atccgccata
    24781 actggtcttg ctataagcaa cagagcagca aatagagcca ccaagaggta gacgaagcgt
    24841 agaggctggt aagattgttg tttcatgata atagttatct ctccctttta tgttatgctt
    24901 tgcttgttaa aaagcagctt gttagtatta tagattaaaa gcagcttaga ttcaaggtcg
    24961 agatgtgaga aaaaaataac tttttgatta gtatatcaaa aaagcttgtc tatgaaggta
    25021 tctcatagac aagctttctt ctgtatttgt gaaaggagta ggcacaaggc ctcaagagat
    25081 aagcagcatc aaggtgcttg acgaacctct tgaaccagtc ctacttataa gtaatcgaac
    25141 catatgggct cagggttgat cctgagatgt tgacattgat ttctttagac agtttcacat
    25201 ctctttcgtc gatcactttt cgccaccatt cccaagctaa gccggtgcac tctctagcca
    25261 tgatacggat atttcttgaa ttagctccta gtgggataac tgtgctaaat ggtgatgtct
    25321 tactatacca gttgttgtcc caacgtcgtt ttgtaatcac ttcttttcct ttgtcatcat
    25381 aattgatttc atcccaaagg atttcatatt gagcaacata cgcgccgcga tgagacaggt
    25441 taatttttcc actagtgtac tcggtagatg ttgtttcaac gtattcagtt ctgttattga
    25501 cacccgcaat tttattattt ttaaggaaaa cactggtgta tgaaatagga taagctgggt
    25561 tttttctact gaaggtagca ttgtctttga taacgtttct aataacatca aagtcttttg
    25621 tgactacctt attgtgctct gcagcatctc ctcctaaaac gacagctgta aatgagctat
    25681 tttctaagat atcagagtat tttccattcg ttttaacatc tgttcctttt agagctgcac
    25741 taaaggccgc ttcaacatca ttacttttag aacttgtttc tagtttgaca aaaacagttc
    25801 gaccatacgc tacgttactc acaaagagtg gcggagcttc attgctgaca ccttttcgtt
    25861 gcaaatcttt aaaagtcact gatttatcaa acacatccgc aggattatta ggaagatttg
    25921 ctgatacggt gtaaaagatt tgcttgtatg ctgcaatcat caccttcttt tcaccttttg
    25981 aaatcgactt gaaatcaatg cctaaagtac catctaagat tttgctatta acatttagag
    26041 ctgcttcaat ctgtgactta gaatatacca ttgattcagt atattgtgtt ctggcaggaa
    26101 gcgtattacc accagaataa ttatcatgcc attggttaac aagattatca atagctgttg
    26161 aaacattggc ataggtaggg tcattgacct caaccgttgc tttgtctccc atacctggta
    26221 aatcaatatg gattttttgt gggtttcgct tggtgactac cgcgtctggt ttgttttcgg
    26281 taaaaccttt atcagccagc tgaagggctg ctggataggt catatcagtg acagagtcaa
    26341 tgatggaaat atcgactggt gtagtgttga tatttttttt ctttctttca atgacaataa
    26401 atttatcagc tttcttaacg ccttctttag gaacaaaatt ttcaatggtt tcaccatttt
    26461 tagcaagtac ttcaagctca ttataattta gtgaataaat cttgtcattg atttcttcag
    26521 tgtgatcttc ttcgctcttt tttttgtctt ctgacttttt ttcttctttt tctgcagatt
    26581 ctagtggcat ttctttggga gcaagcttaa tcatatcgtt agagttaagc atatcatcca
    26641 ttttctgacc tgctttttcg atagttagct cactactttc tggttttggt tgctcatttg
    26701 tcgttgtggt ttctgtacta gcagtgtttt gtttgttcga ttcagcatta gcagtaacaa
    26761 gattaccaat gataagagct gccgttagta gcccagcgac gcgactgtat tttttaaatg
    26821 tttttttatt agacatgtcc ttcatacctt tttatcattc taaaatgttt ctattgttct
    26881 ttcgaccata tcaagcatag tatcttgata gtgagcaaat tctcctaatt tgtaatgtgc
    26941 catagcctct ctaatatgcg catcttttaa cgctttggtc atattagcta ctatgctttg
    27001 acggtttaaa taaaatggca agctttcgta ataatttaat aacatgtttt cagcgtttag
    27061 ggtttgaacc gcttggtaaa tgtctaatgc ttgaccgcta tttgacattt ctaataatgc
    27121 ttcttcgatg ttagctttca attgggtata gccttttatg aaagcagggt aaaccccata
    27181 ctctaaaata acttctggat cagaaatatc tcccatataa gagtctctcc tagtgatacg
    27241 atactctttg tcactaccta tcaagtattt ttttaaatca ttaacagtta cttctttttg
    27301 aaacattttt tggtaatgtt ctaaaccctt tggcacctta tacatattgt tacttcctat
    27361 cttgcattct atcttgcatt ttcttaattt tgaagcgacc agttactttt ttatggtcac
    27421 catttggagc aatgatggta ggatcaataa tttcaaaata gcctttggca tcaatctctg
    27481 ctaagacagc tttagatttt agatctttaa cactaatcga tgggaaaatt aattcacttt
    27541 ctgaattttc aatgtgtttt cctgaccacg tttggcaacc aggaatgttg agcgaatttg
    27601 ctccaggagt atctccgcta gctgttcgga tatagcctag cttatcaatg ttttttgtta
    27661 gttcagaatc gtactcatat tgataaaccc catcactata ttttccgcta tcgacacctt
    27721 ttatattttc aatttggtca gctgatttta acttaccttg atcagtaaag agcaatgcca
    27781 tatcttcagc aaaacttgtc acaaaaagac cgttttcttg tcgaccaatc gttgactttc
    27841 ttttagcatc gtcaaaagct aacatcaaat cttttttgct tgtaacgtgg gaagctccgc
    27901 tttctttgta gacttgtttt agtttttcaa caaactcttt tttgtagtgg tatttgcggc
    27961 taacgtacat ccggtaatac tcagcacgtg acgcaacagc agacatctga acagctttat
    28021 cagcatactt gtcggcagtt tcaataaact catctgcctg tttatctgtt acccatttat
    28081 ctttaatttc tttaaacttt ttttcaaaaa tatcgcgttc tatattgcca aaagtgacct
    28141 ctgacaaggc taaaatatcc ttgttttgtc cctgatggac ctctgttacc tcaatatcaa
    28201 tacgatcaac atctaatttt ttatcaatct caatgtgatg cggtttttta gtgtaggtgt
    28261 cgcctaattc aattttttga aagaggacca atttattccc gttatagtat ttaacatcag
    28321 cctttgcaat tctatttttc ttgtagtaat tctccttgct agatgtatct ccattaacaa
    28381 ttaaaattct cccaatatgc atcggggaag caaacttgta ggaaagtacc tcaccaacac
    28441 caccaccagg tgaattttcc tcccagacag tactcattga gccgtctaat gtgtgcatga
    28501 catgattgtc ttctttagag gaagttgcgt tagcttccat aactttggtc gtttcatatt
    28561 tgacatcgct ttttttattt tctttgccac taacagcgta tgttgtgcta ttagctaata
    28621 aactgctacc cattgctcca gccaaagcaa tagcaacact tgtctttgcg acaatatgag
    28681 ctaatgttac ttttttgttt ctcatgtaaa ccaccttata ttatttttaa gtaaactata
    28741 cattagcaaa tagtttttgt caatgcgatt tattaacatc attttagact tttctatcaa
    28801 aaaaatgaac acaaaaaaac aagtagccaa ctgttacaag tttcaagggg atatttccat
    28861 cttattatca cagaaccttc acatctgttc tatttaaacc agattaaaag tactagttaa
    28921 atatttgata gtagcaccgt tatcagtaat agatctgtta attatctctg attacaatga
    28981 tgttaacgat agtcatacct ttgtttgtac acacgcttca cttccaacta aaaaaggtct
    29041 gatggtaata cttataccat cagacctttg agagcctata gttctgcaat ttgataaagt
    29101 tcaacttctg ctactgtttc agagccaaac atgttgagca tcagtttcac tttgttgttt
    29161 tcgatttcta ccacacgacc ttcttgtccc ataaaggcac cgtctatgat ctgaaccaca
    29221 tcgccttctt tgatattggt atcaaagaca tcaatggttt gacccataga caacaagata
    29281 gcacggattt cttcttcaag aagtggtgtt ggttttgatc ggttcccgtg tgatcccaca
    29341 aaacctgtaa cgtttggtgt gttacgcaca acaaaccaag cttcatctgt catgaccatt
    29401 tcaaccaaga cataccctgg aaagcgattt tcttcgattt ctttggtttg cccatttttt
    29461 tcaacgttaa ccgtttgtgt cggaatttcg acgcgcaaaa tattgtccaa catgttatag
    29521 gtttgggcac gttgcaagag gttttctttt actttgtttt cgtagcctga gtaagtttgg
    29581 aggacgaacc agcccttatc aaatgaatct agcatgatgt ttcctttcat tataaaaaag
    29641 cccttttttt ggcttttgcg ctgttttcta tcaccttcat tataataaaa gacagggctg
    29701 ctgtcaacgt atctgtggag ctacttgaca cctttattaa aaagtccaaa gtcggttcgt
    29761 gacgactctg gacggtattg tacagtttta gttttcagga actgtgatgg tcccttcgat
    29821 aatcgctttt ttagcagcct caatagcttt tttagtgtct tgtgtcagag catccgttgt
    29881 aaggctaaca ccaccttctt ttaaaccaaa agtggttatt tgaccacctg ggaattggcc
    29941 ttctgaggtt tttacggcta cttttactaa agcttttccg acttccttga tacttgaggt
    30001 caaaacaaaa ttagctgact tgccatcttt tgtggtgtat tttccatctt cactttggtc
    30061 acggtcaaca ccaataaccc aaaccttatc ttcttcttta cgtttttcgt taatagactt
    30121 agcttcgcta aagacacccg ctcctgtgcc tcctgctgca tgataaataa catctgcgcc
    30181 ttcagcgtat tgagcagctg caatcgtctt gcctttagca gcatctgcaa aagagcctgc
    30241 ataagcaact cttactttga tggtatcatc tactgatttc acaccagctt caaaaccttt
    30301 ttcaaagcgc ttgacaacat ctccttccat accacctaca aaaccaactt gcttggtttt
    30361 tgtcgtttta gctgctgcaa caccggctag gtatgccgct tcatggtctg aaaaggtgat
    30421 acttgcaaca tttttttgac ctttaatcac atcatccaca attgcaaaat ggttgtcagg
    30481 attgtttgcg gctacttttt ctacagcgtc atgtaatgga aatccaatcc caaaaacaag
    30541 attataacca ttggttactg ctgactcaag gtttgtggta aactctgatt cattggctga
    30601 ttggaaataa tcatagcctt ttcctttttc aagtttattt tcttttcccc aagcttgtaa
    30661 gccttcccag gctgactggt taaatgactt gtcatcaata cccgtctgat tagtaatcat
    30721 agcgattttt aatgaattgt cagttgtttg tttagcggag ttattggtac agcctcctaa
    30781 tgtgaatagg gcagtcgaaa caagaccaag tgacattact tttttgttca tgtgaaaatg
    30841 aacctcctaa atgtttaatc ctaaagtgat gtgtcattgt taacgttcta cttatgctct
    30901 agaacgaaaa gtttagtata tcaaaaaaat cagttttatc ctactatttt tgttgaaaaa
    30961 tctctttttc accaaaatga ccgaacgata aagtgagatc aactggtaaa acccattatc
    31021 tcctcaaaaa tcacctctta aggagataag tcaacgacaa aactcaagct actagtaata
    31081 gcatgactaa ctatacaatc caacaagcgg taaaaagagc tggaaacgct attcaactct
    31141 ttgtcatact agacacctta gatagatgcc cagaccgact caagaatatt ggtctgttca
    31201 cgtcctggac caactgagaa ggttgaaatg cgaacgccaa ccaattctcc aacacgacgg
    31261 acatagttgc gggcattttc aggcagctca tcaaggctac gaacacccgt gatgtcctct
    31321 tgccagcctg gtaattcttc atagattggt ttgcaacgtt tgagttgttc aagacttgct
    31381 gggtaatagt caatacgttt cccatcaagg tcataagcca cacaaatctt aaccgtatca
    31441 agccctgaaa gaacatcaat tgaattcaga gagaggttag taatacctga tacacgacga
    31501 ctgtggcgca taacaactga gtcaaaccaa ccgacacgac gtggacggcc ggtcgttgtc
    31561 ccgtactcat gacccacttc acgaatgcgc tcacccactt catcaaagag ttctgtaggg
    31621 aacggcccat caccgacacg gcttgtgtag gctttacaga caccaactac tttgttgatt
    31681 ttacttgggc caacaccaga accaatggtt acaccaccag caactgggtt tgaagacgtt
    31741 acaaatgggt acgttccttg gtcaatatca agcataaccc cttgtgcacc ttcaaaaaga
    31801 acacgtttac cggcatcaag tgcatcattt aaaattacag aagtatctgt cacatattgc
    31861 ttgatttctt gaccgtaagc atagtattct tcaaaaatag catcaaaatc aagaggtgta
    31921 ctgtcataca ttttttcaaa taaacggttt ttctcagcta aattaatgcg taggcgctct
    31981 gcaaagatat ccttatccag taaatctgcg atacggatac caactcgagc agctttatcc
    32041 atataagctg gaccaatccc tttaatagtt gttccgattt tattgtcacc ttttgcatct
    32101 tcttgcagtt gatccagctg gatatgataa ggtaaaatga catgagctcg gtctgaaatg
    32161 cgaaggttat ctgtcgtcac tccttcatca tgcaggtacg ccaactcttt gaccaaagat
    32221 ttggggttga ccacaacgcc attaccaata acggaaattt tttgcgggaa gaaaattcct
    32281 gatgggatca agtgaagttt aaacttctta ccatcaatca cgatcgtatg accagcatta
    32341 tcaccacctt gatagcgtgc aattacttct gcatccgctg acaagaaatc agtgatttta
    32401 cctttacctt cgtcacccca ctgggtacca acaacaacta cagatgtcat atcattgtcc
    32461 taactttctg aaacacttat tctcaataaa aatcataggc aagctaacca ctgcttaaaa
    32521 accaaaaaga aggtcagatc tgtaagatca gcaatgtagc gtcttgatat ttaaagaaaa
    32581 caggcaggaa tctcacctgc tagcatatat cttacaactt attatagcaa aaaatgattt
    32641 tttctgctag atttcttagc attattaagg aaaaagagaa actctttttt taaccatgat
    32701 aaacaatcct aaaaaaacga acattataag agaaaagctt ttaacctcgt ttctcctaag
    32761 ctttagcagg gttaaacgat tctcttaaaa cattagctct tttctttcag aaatagcggt
    32821 tttaaggtaa aataatagta agttacctct atgagatagc cagtaaaaac atatcgagga
    32881 aatatcacat gattagaaag tatgaccgca cgagcacaaa aaagaaatca ctaaactgga
    32941 tttggctaat cattgctttt tttatgattt caagctttat aggtggctct tcttttactg
    33001 agtcacttct agacattttg cctgccatag ccattggtgg tacaggttat gctatttttc
    33061 gtgttagatc tcatcaaaag cggctagcaa aggccaagat tgccaaacaa ttagaagatc
    33121 taaaagcaaa aattcagcta gctgatcgta aagttcggct gttagacact tatctggcag
    33181 accatgatga cttccaatat aacgtactag ctcagcaatt attaccacaa cttagtgaca
    33241 tcaaagcaaa agctattacg ttaaaagacc agttagatcc caaaatttat cgtcgtatca
    33301 ccaaaaaagc caatgacgtt gaaagtgata ttacccttca actcgaaaca ctgcagattg
    33361 ccacaactct taaccctcag cctttgaaaa ccccatctcc taatcttatt aacaaagcac
    33421 ctgagctcaa accgtattat gataatattc agacagatca tcaagctatc cttgctaaaa
    33481 tccaaggagc cgacaatcaa gaagaattgc ttgcgctaca tgaagctaat atgagaaggt
    33541 ttgaggatat cttaacaggc tacttaaaaa tcaaagaaga gcctaaaaat tactataacg
    33601 ctgctgctcg tttagaacaa gccaaacaag ctatccaaca atttgatgaa gatcttgacg
    33661 aaacccttcg tcgactcaat gaaagtgatc ttaaagattt tgatattagc cttcgaatca
    33721 tgcaaggtac tactcaaaga cgaacaacgc atcaccaaaa agactaaagg agtcccttta
    33781 tggcagattt taattttgac attgaccaaa ttgctgacaa tgctgttgtc aaaaccgata
    33841 aaaccaccga tattatctca gacttaccaa ctgacacaaa tggccaaatc tctttttttg
    33901 agaaactaag tgctgaccag cagacagcta ttactgccaa agccccggca ttggtagata
    33961 cctttttggc agaccaaaat gcgctacttg attttggtca gtctgctgtt gaaggggtca
    34021 atgcaacggt taatcatatc ttggcagagc aaaaaaaatt acagattcca caagtggatg
    34081 atcttttaaa atcaaccaat cgtgaactca atggttttat cgctaaatac aaggatgcca
    34141 cacctgtgga ccttgataaa aagccaaact ttcttcaaaa actctttaaa caaagccgtg
    34201 ataccctgca agagttttat tttgattctc aaaacattga gcaaaaaatg gatagtatgg
    34261 ctgcagcggt tgtcaagcaa gaagatacct tagctcgcaa tattgtctca gcagaattgt
    34321 taattgaaga taatactaag tccattgaac atttggtagg cgtcattgct tttatcgaag
    34381 ctagtcaaaa agaagctagt cagcgcgctg cggctttaca aaaagaccta aaaaccaaag
    34441 acagtgctac accagactat caaataaaaa ctgatctttt ggcaagaact accgaagtca
    34501 tcaacactct cgaacaacaa cacaccgaat acttgagtcg cctctatgtt gcttgggcga
    34561 caactccgca aatgcgtaat ctagtcaagg tctcttctga catgcgtcaa aaactaggca
    34621 tgttacgccg caataccatt ccaacgatga aactatctat tgctcagtta ggcatgatgc
    34681 aacaatcggt taaatctgga ataactgctg atgccattat taatgctaat aatgctgccc
    34741 ttcagatgct agcagaaaca agtaaagaag ccatcccagc attggaacaa tcagcacaaa
    34801 accctacttt gtctatgaaa tctgtgacaa gtctggcaga aagtttagta gcacaaaata
    34861 atgggatcat tgcggcgatt gatcatggac gcaaagaacg agcacaacta gaaagtgcta
    34921 ttatcaggtc tgccgaaacc attaacgatt ctgtcaaact acgtgaccaa aatattgtgc
    34981 aagcacttct tagtgaaggc aaggaaactc aaaaaacaat tgataaaaca actcacgcat
    35041 aagctaaaca tcacctgtca cgctacttaa aaagcaagcc atcagttagg ttaatcc
//
LOCUS       DATTYN010000017        33103 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.17, whole genome shotgun sequence.
ACCESSION   DATTYN010000017 DATTYN010000000
VERSION     DATTYN010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33103
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.17"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..1194
                     /locus_tag="VB649_001067"
     CDS             <1..1194
                     /locus_tag="VB649_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670025.1"
                     /translation="VWLVIISIIIIVSGIFLQETKASQSRINRQISQLSPWNKVRNWK
                     RLELLGIENGSINNGEINEPESQYIQIATALKKLDFIYIKPSSVYIPDYMKNTNFAED
                     FFKKLNNDGITDPEVNKEMIYINKSGANIQNKVNGTDYQLLDNKVATIYIPDKFKEKK
                     KSIENTVVAEQFTGTKYTKENLAVQIIPNEKKIFYFNENGNEHDENKEASPMANVTDS
                     KGNIVVVLDTDKMVASKDFSLASNIVNSSLFSPEAIKKINDLSLHLNFSINPVDVYQL
                     VKLNIQSLKHQIFLSKVLQKIIYGIVFLLIYQYAQLFISSKQNDYVKKIILGLSKTRI
                     AISSLKYFIMTIAIVIICTFMVTEQIELLYIGIASLVVLIISTVMSFRKLSKKYTQIL
                     KGDEQ"
     gene            1191..1814
                     /locus_tag="VB649_001068"
     CDS             1191..1814
                     /locus_tag="VB649_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP1670026.1"
                     /translation="MTIEIFNVTKKFSSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDNGKVLVDEQDIWKIKERTFFKNIIGYVFQNYSLIENKTVYDNLKLIN
                     KDKKKISAVLEKVGLSSDYLNQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDFIIDMKDIGSKK"
     gene            1811..2302
                     /locus_tag="VB649_001069"
     CDS             1811..2302
                     /locus_tag="VB649_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670027.1"
                     /translation="MKKKIYIGLIVIVGVFVVFLSGKQIIQKETSNKPEVTLTVYTIS
                     SSDTQKWSKVKQFETKEAIYLVKVKETTSSEEVFSNIIADGMAVGFGVSEEDVKQFND
                     NLCSPVEDAKNNKLIGIEFINFSSVDKGFVVANFDYGKKAFNSQKTENKKLYKKLYEA
                     YKG"
     gene            2506..3036
                     /locus_tag="VB649_001070"
     CDS             2506..3036
                     /locus_tag="VB649_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEP1670028.1"
                     /translation="MGIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNEKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDAQLAS
                     KDEQMRVKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEANQARLQVEEVQ
                     AEVGPKKGFLTRLFAK"
     gene            3085..3672
                     /locus_tag="VB649_001071"
     CDS             3085..3672
                     /locus_tag="VB649_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEP1670029.1"
                     /translation="MQHLDTYIAFDLEFNTVNDVSHVIQVSAVKYDHHKEVDSFDTYV
                     YTDVPLQSFINGLTGITSDKIAAAPKVEEVMAAFKNFVGELPLIGYNAQKSDLPILAE
                     NGLDLRDQYQIDLFDEAYDRRSADLNGIANLRLQTVATFLGIKGRGHNSLEDARMTAA
                     IYKSFLETDTNKAYLSQQEEVTTDNPFAALGDFFD"
     gene            3825..4118
                     /locus_tag="VB649_001072"
     CDS             3825..4118
                     /locus_tag="VB649_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEP1670030.1"
                     /translation="MSQFYSTGELANLAGVSIRTVQYYDQRGILIPTALTAGGRRLYT
                     DSDLEQLRMICFLRDLGFSIAGHTPRTRKLTCSHCHQKSYCLELAKEDTVSRR"
     gene            complement(4175..4474)
                     /locus_tag="VB649_001073"
     CDS             complement(4175..4474)
                     /locus_tag="VB649_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEP1670031.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFT
                     GDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF"
     gene            complement(4667..5041)
                     /locus_tag="VB649_001074"
     CDS             complement(4667..5041)
                     /locus_tag="VB649_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670032.1"
                     /translation="MSAKKTFFASNLKYLRLKKNMEQLELANLLGRKSSSSISEWEKG
                     KYTPKSGLLSDIAAIFDVSLTALMEEDLTLESKGVSYQLPQRELAMISEQLSENNYTK
                     WVDFAQILLEQQAKEDRELDNH"
     gene            5211..5432
                     /locus_tag="VB649_001075"
     CDS             5211..5432
                     /locus_tag="VB649_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670033.1"
                     /translation="MTKSTLKELRTTKKMTQQELSHLTGISVRTIARYEKDTKKLRRA
                     KYEKLKGIAQALAVSVDDIFLGIDSEFMN"
     gene            complement(5512..7794)
                     /locus_tag="VB649_001076"
     CDS             complement(5512..7794)
                     /locus_tag="VB649_001076"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEP1670034.1"
                     /translation="MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKL
                     FFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADA
                     FLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSL
                     ATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINE
                     VANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLND
                     YFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQV
                     RADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLAGDYLRHNDHYQELLNQQSQALDRQSGDYNQFWHDRNY
                     LKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSI
                     DFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELL
                     LIDNHYGEDEFKAYGKDFRASKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSS
                     ENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFRKDSYRVISKG
                     FMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNS
                     NYALTIDLSQSQLIVPIASN"
     gene            complement(7816..8475)
                     /locus_tag="VB649_001077"
     CDS             complement(7816..8475)
                     /locus_tag="VB649_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEP1670035.1"
                     /translation="MNHHILQRYIDNHNFPIIEKSYHKYLTFESLEEDFTYILKDGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMGEPYNVRIESEKASFYKVRRSAFL
                     KDINEDIELQGYVKDFYHNRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGEELPNG
                     QILINFVITNEELGKFCGISTASSVSRILKQLKEKNIIRIDKQHIIITNLDKLKDNIV
                     F"
     gene            8641..9837
                     /locus_tag="VB649_001078"
     CDS             8641..9837
                     /locus_tag="VB649_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP1670036.1"
                     /translation="MEEKLFNKHFVAITVINFIVYMVYYLFTVIIAFVATRELGAQTS
                     QAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFYMPTISMMYL
                     VRFLNGFGYGVVSTATNTIVTAYIPARKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIVLCSVLIGCVVVGAFAFPVKNMSLNAEQLAKTKSWTVDSFIEKKALFITA
                     IAFLMGIAYASVLGFQKLYTSEIHLTTVGAYFFVVYALIITITRPAMGRLMDAKGDKW
                     VLYPSYLFLAMGLFLLGSVSSGGSYLLSGALIGFGYGTFMSCGQAASIQGVDEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDLALGSGVASFRHLFWLAAVIPLICTLLYLLKTK
                     TRQVVS"
     gene            10339..11187
                     /locus_tag="VB649_001079"
     CDS             10339..11187
                     /locus_tag="VB649_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEP1670037.1"
                     /translation="MEMTWTVKYITEFIATAFLIILGNGAVANVDLKGTKGHNSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTVGLAVSGLFPWAHVLQYVVAQLLGAIFGQ
                     LVVVMVYKPYFMKTENPNHVLGSFSTISSLDNGQKDSHKASYINGFLNEFVGSFVLFF
                     GALALTKNYFGVELVGKLIEAGYDQTTAATQISPYVTGSLAVAHIGIGFLVMVLVTSL
                     GGPTGPALNPARDFGPRLLHHFLPKSVLGQAKGDSKWWYAWVPVVAPILAAIVAVAAF
                     KYLYIR"
     gene            complement(11522..12418)
                     /locus_tag="VB649_001080"
     CDS             complement(11522..12418)
                     /locus_tag="VB649_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEP1670038.1"
                     /translation="MNEMLILRLIQTLLVSAMLFIFFMLVKHLKKNKINPFKRFWTGF
                     WIGLLTDALDTLGIGSFATTTTCFKLTKLVTDDRQLPGTMTVAHVLPVLIQSLCFIFV
                     VKVEVLTLLAMAAAAFIGAYFGTHITKNWHAPTVQRILGSLLIIAAIIMIIRIIYHPG
                     EHLSDTIHGLHGIWLFVGIGFNFIVGVLMTMGLGNYAPELIFFSLMGLSPTVAMPVMM
                     LDAAMIMTASSSQFIKANRVSWDGFAGIVSGGIIGVLLAVFFLTNLDINSLKLLVIAI
                     VFFTGGMLIRSSFTSHKQQTNR"
     gene            12716..13468
                     /locus_tag="VB649_001081"
     CDS             12716..13468
                     /locus_tag="VB649_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEP1670039.1"
                     /translation="MTLMENITFKTPVLRVNDRDLNIAFYQNNLGLRLVSEENAIAIF
                     SSWGEGQECFVIEESPSVRTRAVEGPKKVNTIVIKTNQPKEIEQLLAHGAHYDTLFKG
                     QNGYAFETISPEGDRFLLHAEQDIKHLQGTDLPSLEKDATFKGLTQFKFDIIVLNVIS
                     EERSKAFYRDLFSDQLPITMDFIQEEGPDLAIDPHIAWDLEILEFQVSKDYDMKVLKA
                     TLEEDGHKVYIDKKHKVLVLSDPSQIEVWFTK"
     gene            13453..14403
                     /locus_tag="VB649_001082"
     CDS             13453..14403
                     /locus_tag="VB649_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEP1670040.1"
                     /translation="MVYEMTLAVIKCIENHLHKKVYKGASLALFQSGRWQEYHIGTID
                     GRRPVDANLVYDLASVSKVVGVATICNILLNNGTLALDDPLKVYYPSIADATVTIRQL
                     LTHTSGLDPYIPNRDVLNAQQLRKALNHLTQKENKNFYYTDVNFLLLGFMLEELFSES
                     LDQIFDKTIFTPFGMYHTSFGPRPEAVPTLKGVSDGEVHDPKAKILKKHSGSAGLFST
                     LADLESFSNHYLNDPFSDCLWRNYSQQTIERSLGWNLDGDWISHTGYTGPFLMLNKKD
                     QTAAIFLTNRTYDEDDKSKWLKERQLLYNALKHDLTTPVS"
     gene            complement(14583..16910)
                     /gene="pflB"
                     /locus_tag="VB649_001083"
     CDS             complement(14583..16910)
                     /gene="pflB"
                     /locus_tag="VB649_001083"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEP1670041.1"
                     /translation="MATVKTNTDVFEKAWEGFKGTDWKEKASVSRFVQANYTPYDGDE
                     SFLAGATERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKENELIYGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEV
                     NLQYQALGEVVKLGDLYGVDVRRPAQNVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFGRTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDQLPETFRRYCMKMSHKHSSI
                     QYEGVTTMAKEGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHRDYKVFNVVEPITSEVLEYDEVMANFEKSLDWLTDTYVDALNIIHYMTDKYNYE
                     AVQMAFLPTHQRANMGFGICGFANTVDTLSAIKYATVKTIRDENGYIYDYEVTGDFPR
                     YGEDDDRVDDIAKWLMEAYHTRLASHKLYKNAEASVSLLTITSNVAYSKQTGNSPVHR
                     GVFLNEDGTVNTSQVEFFSPGANPSNKAKGGWLQNLNSLAKLEFSHANDGISLTTQVS
                     PRALGKTFDEQVDNLVTVLDGYFENGGQHVNLNVMDLNDVYDKIMNGEDVIVRISGYC
                     VNTKYLTPEQKTELTQRVFHEVLSMDDAAEAISSK"
     gene            17119..18213
                     /gene="dinB"
                     /locus_tag="VB649_001084"
     CDS             17119..18213
                     /gene="dinB"
                     /locus_tag="VB649_001084"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEP1670042.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPALKGKPVVIGKD
                     PRETGGRGVVSTCNYEARKYGIHSAMSSKEAYERCPKAIFISGNYEKYRTVGDQIRRI
                     FKRYTDVVEPMSIDEAYLDVTDNKLGIKSAVKIAKLIQHDIWKEVGLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLKEDALCFLAKLPIEKFHGVGKKSVEKLHDMGIYTGQDLLA
                     VPEMTLIDHFGRFGFDLYRKARGISNSPVKSDRIRKSIGSERTYAKLLYQETDIKAEI
                     SKNAKRVAALLQDHKKLGKTIVLKVRYADFTTLTKRVTLPELTRNAAQIEQVAGDIFD
                     SLSENPAGIRLLGVTMTNLEDKVADISLDL"
     gene            complement(18304..18774)
                     /locus_tag="VB649_001085"
     CDS             complement(18304..18774)
                     /locus_tag="VB649_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670043.1"
                     /translation="MISYEKVRQALKTSTIAIIILNGLGVVRSLMGFAGIFYLQSQLK
                     NEAFRAQLTTEQLAQLQSSMTPFMIFLSVLNVLAIIAIIVFCAQNLSKLKQGLTVSYI
                     PYILGLTLSVIGLVNQFTTTLSMVGTILILIQAALYGFAFYKAKTLNEKGDAML"
     gene            complement(18865..21318)
                     /locus_tag="VB649_001086"
     CDS             complement(18865..21318)
                     /locus_tag="VB649_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEP1670044.1"
                     /translation="MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITG
                     TMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIKPSSSGLVNYFSSDHFKGIGKKT
                     AEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
                     LSNRFALQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFR
                     AALLHCLLEESINRGDTYVQARQLLDFTITLLEDARQVECDPAAVAEQLSELIIEGKI
                     KNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTIQAVQKDFAITYDQV
                     QQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGR
                     AARRMNELTGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLG
                     AINSTTQVIIVGDSDQLPSVGPGQVLSDLLKVNSLPQIALQKIFRQSQESTIVNLADQ
                     MRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILAPMYKGQ
                     AGINHLNQLMQELLNPLQGQTEFLFNDTYFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDELILDFDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQ
                     SGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEGDKRQTYLIERFQEQSDLASS
                     QPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTI
                     DSMIGLTESDVALFFQKKS"
     gene            complement(21376..21969)
                     /gene="lepB"
                     /locus_tag="VB649_001087"
     CDS             complement(21376..21969)
                     /gene="lepB"
                     /locus_tag="VB649_001087"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEP1670045.1"
                     /translation="MKQFIKEWGPFTLFLILFGLSRLFLWQAVKVDGHSMDPTLAHGE
                     RLIVFNQARIDRFDIVVAQEEENGQKKEIVKRVIGLPGDTISYNDDTLYINGKKTVEP
                     YLAEYLKQFKNDKLQKTYAYNTLFQQLAETSDAFTTNSEGQTRFEMSVPKGEYLLLGD
                     DRIVSRDSREVGSFKKENLIGEVKARFWPLNKMTVFN"
     gene            complement(21980..22882)
                     /locus_tag="VB649_001088"
     CDS             complement(21980..22882)
                     /locus_tag="VB649_001088"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEP1670046.1"
                     /translation="MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVL
                     LYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAV
                     VASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
                     SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLT
                     FQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYG
                     MSSLEYSAKLHFANTHKAQALLTK"
     gene            23039..23347
                     /locus_tag="VB649_001089"
     CDS             23039..23347
                     /locus_tag="VB649_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670047.1"
                     /translation="MKSINRYKFTFGEKTLTLTTDKDNLFMEEVERVAKEKYQALKNH
                     LPEADDETIAILMAINTLSTQLSREIAIEKMEAEILDLRQKTLVGLQEKANQIDVNEV
                     "
     gene            23350..23895
                     /locus_tag="VB649_001090"
     CDS             23350..23895
                     /locus_tag="VB649_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEP1670048.1"
                     /translation="MLSLLIVLVLTWNFYIGYSRGIILQSFYVLGALLSFLVANRFYI
                     GLAHKLTLWIPYSNPVEGTSVFFFKSVDIFVLDKVYYAGLAFFIIFLLGYALSRFLGI
                     FVHFLLLDYFDNQWTKCLSGGLALLVSLLFLNMLLSIFATVPMPFLQHYLHSSFLARL
                     VIEHLPPLTIIIQKLWIQAII"
     gene            24044..26383
                     /locus_tag="VB649_001091"
     CDS             24044..26383
                     /locus_tag="VB649_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEP1670049.1"
                     /translation="MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIE
                     KSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLELSTDLNIQELLAIKKVLQSSSDM
                     IHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
                     SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTV
                     YIEPRAVVTLNEEITQLRADEHHEEGRILHTFSDLLRPHVATIRNNAWILGHLDFVRA
                     KYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDQDLTAIVITGPNTGGK
                     TIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHI
                     VSILNEADHNSLVLFDELGAGTDPQEGASLAMAILEHLRLSNIKTMATTHYPELKAYG
                     IETNFVENASMEFDAETLSPTYRFMQGVPGRSNAFEIASRLGLAPFIVKQAKQMTDSD
                     SDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKELEKIYQ
                     EAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKK
                     IKAARAPRIGDDIIVTSYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFTLVRVQEEQ
                     KVKSKQINVVKKADSSGPRARLDLRGKRYEEAMQELDHFIDQALLNNMGQVDIIHGIG
                     TGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG"
     gene            26387..26887
                     /locus_tag="VB649_001092"
     CDS             26387..26887
                     /locus_tag="VB649_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEP1670050.1"
                     /translation="MESYEQFYAKLSQPFRKSPQLIILLNFLLKIVTGMMYILYPSFL
                     IFTLWQGMTFQLWLRLLIIPAVGFIALSYIRKRFDCPRPYEKWNIKPLIDKDTKGRSM
                     PSRHVFSATMISMCLLRYYVYFGIVCLILSVLLAICRVIAGIHYPKDVIVGYLIGLML
                     GLCLLI"
     gene            26968..27282
                     /gene="trxA"
                     /locus_tag="VB649_001093"
     CDS             26968..27282
                     /gene="trxA"
                     /locus_tag="VB649_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEP1670051.1"
                     /translation="MALEVTDATFVEETKEGLVLIDFWATWCGPCRMQAPILEQLSQE
                     IDEDELKILKMDVDENPETARQFGIMSIPTLMFKKDGEVVKQVAGVHTKDQLKAIIAE
                     LS"
     gene            complement(27328..27921)
                     /locus_tag="VB649_001094"
     CDS             complement(27328..27921)
                     /locus_tag="VB649_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670052.1"
                     /translation="MEIGQQIIRYRKQQALSQEELAEKVYVSRQSISNWENDKTYPDI
                     HSLLLLSQIFQVSLDQLIKGDIEKMKYTITQVDKKNFERDTKVMVTLMILLMISSYPL
                     VYFLEWLGLGIFVLLSIITMTYANRVERFKKKYDVQTYKEILAVSSGKLLDEIEKREE
                     RAKLPYQKPLIVTVFFLITVATFFASRFIFTWLFHLS"
     gene            complement(28098..29222)
                     /gene="mutY"
                     /locus_tag="VB649_001095"
     CDS             complement(28098..29222)
                     /gene="mutY"
                     /locus_tag="VB649_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEP1670053.1"
                     /translation="MWDNETIASFRRTLLGWYDQEKRDLPWRRTTNPYYIWVSEIMLQ
                     QTQVNTVIPYYKRFLEWFPQIKDLADAPEEQLLKAWEGLGYYSRVRNMQKAAQQVMVD
                     FGGIFPHTYDDIASLKGIGPYTAGAIASISFNLPEPAVDGNVMRVMARLFEVNYDIGD
                     PKNRKIFQAIMEILIDPDRPGDFNQALMDLGTDIESAKTPRPDESPIRFFNAAYLNGT
                     YGKYPIKNPKKKPKPMRIQAFVIRNQNGQYLLEKNTKGRLLGGFWSFPIIETSPLSQQ
                     LDLFDDNQSNPIIWQTQNETFEREYQLKPQWTDNHFPNIKHTFSHQKWTIELIEGVVK
                     ATDLPNAPHLKWVAIEDFSLYPFATPQKKMLETYLKQKNA"
     gene            29420..29713
                     /locus_tag="VB649_001096"
     CDS             29420..29713
                     /locus_tag="VB649_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670054.1"
                     /translation="MFQKLKNLIDRYSWFVFIMMILVLFLNYIYPFDPSLSGLQLEWL
                     IMTQVFPGLGIVCAMVAIIFKKFNLFVLALILYFALWLKLFLAFSFFTYFLGV"
     gene            29886..30176
                     /locus_tag="VB649_001097"
     CDS             29886..30176
                     /locus_tag="VB649_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEP1670055.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA"
     gene            30198..30689
                     /locus_tag="VB649_001098"
     CDS             30198..30689
                     /locus_tag="VB649_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP1670056.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRTFKSQNGER
                     EADFINCVIWRQPAENLANWAKKGALIGVTGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREGGSTGSFNGGFNNNTSSSNSYSAPAQQTPNFGRDDSPFGNSNPMDISDDD
                     LPF"
     gene            30854..31093
                     /locus_tag="VB649_001099"
     CDS             30854..31093
                     /locus_tag="VB649_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEP1670057.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(31226..31882)
                     /locus_tag="VB649_001100"
     CDS             complement(31226..31882)
                     /locus_tag="VB649_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEP1670058.1"
                     /translation="MELQELTKKNQEFIHTATNKLIQDGKSDEDIKLILEEAIPAILE
                     NQKKGVTARNLLGTPTAWAASFSQDPSQRAAETDKNTNPWLMWLDTSLLFIGIVALLN
                     GIMTFFNTNATVTGLISLLALGFGGGASMYATYYFIYRHLGKDKSLRPSWFKIIAALS
                     LAMLIWIALYSATAFLPTSLNPQLPPLALLIIGGVSLALRYYLQRKYNIQNTMSPVNK
                     "
     gene            complement(32014..32958)
                     /locus_tag="VB649_001101"
     CDS             complement(32014..32958)
                     /locus_tag="VB649_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEP1670059.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESMKIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPIYEERNNKSYYITMPLGIIVTENAVITT
                     CLHDMTLFDHFHNRRVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QNNWLPLNGLEHAFWYITLIAMLLSSFVVIYFIRKKWF"
BASE COUNT        10368 a         5692 c         6613 g        10430 t
ORIGIN      
        1 gtatggcttg taattatttc tattataata atcgtctcag gaatcttttt acaagaaaca
       61 aaggctagtc aatcaaggat aaatagacag ataagtcaac tatccccatg gaacaaagta
      121 agaaactgga aaagactaga gttgttgggg attgaaaatg gctctatcaa taatggggaa
      181 ataaatgagc cagaatcaca atatatacag atagcgacag ccttaaaaaa attagatttt
      241 atatatatca aaccctcttc agtatatatt ccagattaca tgaaaaatac taactttgca
      301 gaagattttt tcaaaaaatt aaataatgat ggtataacgg atccagaagt aaataaagag
      361 atgatttata tcaataaatc gggcgctaat attcaaaata aagtcaatgg aacagactat
      421 cagctgttag ataataaggt agcaacaatc tatattcctg ataaatttaa agagaaaaag
      481 aaatcaattg aaaataccgt tgtggcagag caatttactg gaactaagta tacaaaagaa
      541 aaccttgcag tgcagataat tcctaatgag aaaaaaattt tttattttaa tgagaatgga
      601 aacgagcatg atgaaaataa agaagcctca cctatggcaa atgtaacaga tagtaaaggt
      661 aatatagtcg ttgtgttaga tactgataaa atggtagcaa gcaaagattt ttctttggct
      721 agcaatatag taaatagctc tctttttagt cctgaagcaa taaaaaaaat taatgacctg
      781 agtctacatt taaatttttc aattaatcca gtagatgttt accaacttgt aaaacttaat
      841 attcaatcct taaagcacca aattttcctt tcgaaagttt tgcagaaaat tatttacggc
      901 attgtatttc tactaattta tcaatatgct caattattta tttcttcaaa acagaatgac
      961 tatgtgaaaa aaataatttt aggcctctca aaaacacgca tagcaatttc gagtctcaaa
     1021 tattttatta tgactattgc aatagttata atatgtacat ttatggtgac agagcagatt
     1081 gagttattat atattggtat tgcttcatta gtggttttaa ttatttcgac agtaatgagt
     1141 tttagaaaat tatcaaaaaa atacactcaa attttaaaag gagatgaaca atgacaattg
     1201 aaattttcaa cgttacaaaa aaattcagct caaaaaaaat atttacagat ttaaatttaa
     1261 cgtttgaagc tggaaaaagc tatgccttga ttggaggttc tggctctggt aaaagtactc
     1321 tgcttaacat tataggaaga ctagaaaaaa ttgataacgg gaaagtttta gttgacgaac
     1381 aagatatttg gaaaataaaa gaaagaactt tctttaaaaa tattatcggg tatgtattcc
     1441 agaattattc tttaatagaa aacaaaactg tatatgataa tttgaaactc atcaataaag
     1501 acaaaaaaaa aatatctgct gtacttgaaa aagtagggct ctctagtgac tatttaaatc
     1561 aaaaaatata tgaattgtct ggagggcagg ctcagcgtgt agctattgca agaatgttaa
     1621 tgaagccacg taaaataatt ttagcagatg agccaacagg agctttggat ggtgaaattg
     1681 gaaaagaaat tattaatttg ttgttgagcg aaacagccga aaataaatac gttattatag
     1741 caactcatga tccagctgta tataataagg ttgattttat aattgatatg aaagatatag
     1801 ggagtaagaa atgaaaaaga aaatttatat tggcttgatt gtcattgttg gagtttttgt
     1861 agtgttcttg tctggaaaac aaatcataca aaaagaaact tcaaataagc ctgaggtgac
     1921 cctaacagtt tataccatct cctctagtga tacccaaaaa tggagtaaag taaagcagtt
     1981 tgaaacgaaa gaagcaatat acctagtaaa ggtaaaagaa actacctctt cagaagaagt
     2041 cttttcaaac atcattgcag atggaatggc agttggtttt ggagttagtg aagaagacgt
     2101 taaacagttt aacgataatt tatgtagccc ggtagaagat gctaagaata ataaattaat
     2161 tggaatagaa ttcatcaatt tttctagtgt tgataagggg tttgtggttg caaattttga
     2221 ctacggcaaa aaagcgttta attctcagaa aacagaaaat aaaaaattat ataaaaagct
     2281 ctatgaagcg tataaaggat agctatttat agtttcttga gagtgatacc acttctgaat
     2341 aataaatgaa ctaacctggc ataccgtttt ctattcatct aacaatgttt tcaagaaata
     2401 attgatgcct ttggcacgac tgaaatgagg tcaaattgac agaatactcc tattatggta
     2461 ctatttttaa taagaatatt cagtgatagt gataaagagg aaaatatggg aattgaaaag
     2521 acagttagtg aactagctga tattttggga gtgagtcgtc aggccgtcaa taatcgtgtt
     2581 aagtctttac ccgaagaaga tcttgacaaa aatgaaaaag gcgttactgt ggttaagcgc
     2641 agtggtcttg ttaagctgga agagatctat aaaaaaacaa tttttgacga tgagcctatc
     2701 agtgaagaaa cgaaacaacg tgagctttta gagattctcg tggatgagaa gaacactgaa
     2761 atcacgcgcc tttatgagca actcaaagcc aaagatgctc aacttgcctc aaaagatgag
     2821 caaatgcgtg ttaaagacgt gcagatcgct gaaaaagata aacaattgga tcagcagcaa
     2881 caattaactg ctaaagccat ggctgataaa gaaaccctaa aactagaatt ggaagaagct
     2941 aaagcagaag ccaaccaagc tcgcttacaa gtcgaagaag ttcaggctga agttggccct
     3001 aaaaaaggct ttttaacccg cttgtttgcg aaataatcac aaaaaatgac gaaggcccta
     3061 tcagggtctt ttttggagga aaacatgcaa cacttagata cttatattgc ctttgattta
     3121 gaatttaaca ctgtcaatga cgttagtcat gtcattcaag tatcagcagt caaatatgac
     3181 caccataaag aagttgacag ctttgacacc tatgtttaca cagatgttcc cttacagagc
     3241 tttatcaatg gcctaacagg aatcacatct gacaagattg ctgcggcacc aaaagtagag
     3301 gaggttatgg ctgcgtttaa aaattttgtg ggagagttac cactgattgg ttataatgct
     3361 caaaaatctg acctgcctat tctagctgaa aatggcttgg atttaaggga ccaataccag
     3421 attgacctct ttgatgaagc ttacgataga cgtagcgcag acttaaatgg gattgctaac
     3481 cttcgtctgc aaacagtggc aaccttttta ggcattaagg gtcgaggtca taatagctta
     3541 gaagatgcca gaatgacagc agcaatctat aagtcttttt tagaaacaga tacaaacaaa
     3601 gcatatctca gccagcaaga agaggtaacc acagataacc ctttcgcagc tttgggagac
     3661 ttttttgact aagggctctg ctatttttaa aaaataacaa aaatccctag ggttagccct
     3721 tgcttgtaac gctaggtcat gtgataagct aggggcatat caagagggag tcgggtgcac
     3781 acgagtcgct tttgatcact aaatgataga aagaaggtgt ggaaatgtct caattctatt
     3841 cgactggaga attggccaac ttagctggcg tttctattcg aactgtccaa tactatgacc
     3901 aacgtgggat tttgattccg acagcattga cagcaggtgg acggcgactc tatacggatt
     3961 ctgatttaga acaattacgc atgatttgct ttctgcgcga tttgggattt tccattgcag
     4021 gccatacacc acgaaccaga aagttaacct gctcccattg ccatcaaaaa tcgtattgct
     4081 tggaactggc aaaagaggac actgtctcaa gaagataagc actaactcat aaaaaaacta
     4141 gcctgagatc cttctcaagc tagtttttgt ttttttagaa tggtaattta ccagcaaaag
     4201 cgcctaatgt tttcttagtt gcttcatcaa tttgcgtaag ggcatcatta atggcttgtg
     4261 tggtcatgtc ttgaagcgtt tctacatctt caggatctac aacagcttct ttgaagtcaa
     4321 tcccaaccaa ttttttatca cccgtgaaag tggcagtgac aaggtcttga gctgattttc
     4381 cagtaaattg catagcagcc aaatccgcct gcttttgctc catttgtttc tgaagctttt
     4441 gtgcttgctt catcatgttt tgcatgttca tcataagact atactctcct taatttaata
     4501 ctaactatta taacacataa aaagaggcaa taaaaacaat gtcagttagt agactagcct
     4561 gtatcagtaa gaaagtcgct atggataaga tggattagca gcaagggtct ggctaatgac
     4621 agaataagtc tagaaatgga ctatttttgt catagactag tccgacttag tggttatcta
     4681 attcacgatc ttctttagct tgttgttcta aaagaatttg tgcgaagtca acccacttag
     4741 tgtagttatt ttcggataat tgttctgaaa tcatcgctaa ctctcgttgt ggcaactgat
     4801 aagagactcc cttactttct aaggttaaat cttcttccat tagggcggtt aaactaacat
     4861 caaagatagc agcaatatca cttaatagac cagattttgg agtatatttt cctttttccc
     4921 actcactgat tgaagaagag ctttttcgtc ctaggagatt agcaagttct aattgttcca
     4981 tgttcttttt taatctaagg tactttaaat tacttgcaaa aaaagttttc ttggcggaca
     5041 tatttttctc cttttcttta tataaaatat gataccataa aagaggttaa agcaaaaggt
     5101 atcgtaaaag atggtctaaa aactctctaa aaacttgact tcataaaaac cgaagtttat
     5161 aataaactta acatgattaa ctaatctcat tttagtgtgg agggaaaatt gtgaccaaat
     5221 caactttaaa agagttaaga acaacaaaga aaatgacaca gcaggaattg tctcacttaa
     5281 caggcatttc tgtcagaacg attgctaggt atgaaaaaga tactaaaaag ctaaggcgag
     5341 caaaatatga gaagctaaaa ggtattgcac aagcattagc ggtttccgtt gatgatattt
     5401 ttttaggaat agattcggaa tttatgaact gagacgatcg ctttctgttt gctattagta
     5461 agaccaatta acaaaaaagt gcttagttat attgctaagc acttttcttt gttaatttga
     5521 tgctattggc acaatcaatt gagactgact gagatcgata gttaaagcat agttgctgtt
     5581 gtcacggaca gtatgttcaa aatcggttgt gtataagatg actcgaaggg tatctccttt
     5641 ttctagatga tagatagttg gttgcaaagg aagtctaaca gtcatccatt tattattagg
     5701 aatagtttca attgacgaca aattattgcg attttgtaaa ttcatgaaac ctttcgaaat
     5761 aacacggtaa gaatcttttc taaatggtag ctctttaagg ggttccctag agaaattttg
     5821 cccattgtca atacttgatt gggtgagagc aataggaaga tcgcccaagc gttttttctt
     5881 accatagtca aggatttgtg cagatagaag tcctttattt tcacttgatt tcacttttaa
     5941 ctgtaggaca atttcaccgt taataggtaa gtcctcttcc agtaaaatat caatcagggc
     6001 ttgattggcc ttgcctttaa agagagctgc tttggacgca cggaaatctt taccgtaagc
     6061 tttaaattca tcttcaccat agtgattatc aattaaaagc agttcctgac cgaggtcaag
     6121 ctctttgatg gttgaggttc caaagacttt acgctcctgc cagttttgtg ggcaggtgtt
     6181 atcctgccag atcatttcag gaaggctaaa atcattagcc aggcctaaga gtttttgaca
     6241 taaaagggca ttcatgcttt cgcgaaaatc aatggattgc caattatgca tgtaaacatg
     6301 ctcaccttga tgtaaaaaga ggtgcttgtt gattgtggaa ggaagcgcat tgaaaatctc
     6361 atagacctgt cttggtttga cattccagtc ttgtaagcca tgagtataaa cgacatcaca
     6421 ctttatttga tgagcatttt ttaagtaatt gcggtcgtgc caaaattgat tataatcacc
     6481 agattgtcgg tctaacgcct gagactgttg gtttagcaat tcttgataat gatcattatg
     6541 gcgaagataa tcgccagcca ataaattacg cgagtaggtg agctcagtta ggacatctag
     6601 atcctctcca ggatagccac caggactaca aactaagcca ttttcgcggt agtagttgta
     6661 ccaagaagaa atagctgatt ctgcaataat catggctaat ccgtctacgc ctgtagtggc
     6721 taaaccagta gacatagttc ccaagtagga ctttccagtc gtacaaacta gaccatttgc
     6781 ccaatcagct ctcacttggt gggtttttga gtggctggtg taggctgtgg ctcttccatt
     6841 tagccaatca ataacggctt taaagctttc aatttgagca tagtctccac tcgtcataaa
     6901 gccagtggaa ccagcagttc ccacaccgga aacatagata ttagcaaacc cacgtgcgag
     6961 gaaataatcg ttgaggctat aggagttaat gtagctaaag ctttctagat tttgacctat
     7021 aggaagtttg caaggctgtg tctcaagagg aataaaatcc ctgtcttcga cagtgatttg
     7081 tctccttttt ttaacgacta actctttttc catacgataa agttttttgt cgttggctac
     7141 ttcattgata ccttgatggt atggactagg tgtcatcaaa gttggtaatg gtttttgaga
     7201 ttgaggacga atgatattaa ccttaataag atcaagttgg ccatcttgat cggtatcaag
     7261 aggtgcttca acgtaaacaa cttctcgaat cagctgtgac gtgtcaaagg tagctaatga
     7321 tttaccgttg aagaaatggt aatcattgtc catagtaagc attccttggc tgaccaaatc
     7381 atcaatcagg gtcatgccag acttacaacg ggtcgctaat aagtggtgga tatgcttgat
     7441 aatttctgtt tcgtcaaagt ggataggaaa ggccagttta tcaaggaaag catcggcctc
     7501 tgtaaaatca actccaggaa taaagccaag gacttgcagg gccagtaaat caaaaacctc
     7561 tttggataac tcttgctctg attgaaaaaa gctcaatgcg tccatgtcat ttttggcgat
     7621 tagatgactt aaaggataat cactatcagg gtagtggaag aagagtttac gtaaaaagct
     7681 ttctaggtta gctttggcag ttttttgcag atccagatca aagcccaatt cttttaattc
     7741 ttcagccgct ctttctagac tagttggaat ataggaaaat tgattatagc gcataggagt
     7801 ttcctttcta gtggcttaga aaacgatatt atcttttaat ttatcaagat tggtaatgat
     7861 aatatgttgt ttatcaatgc gaatgatgtt tttttctttc aactgtttta gaatacggct
     7921 gacgctgcta gcggtagaaa tgccacagaa tttaccgagt tcctcattag taatgacaaa
     7981 attaattaaa atttggccat ttggtagttc ttcgccaaat agggtcatta agtcatatat
     8041 ttgagtagaa atggcaccga tacggccgtt agttaacata cattgcattt ttttcatgga
     8101 tttttgaaga cgattatggt aaaagtcctt cacatatcct tgtagttcaa tatcttcgtt
     8161 tatatctttt aaaaatgctg agcggcgaac cttgtaaaaa ctagctttct ctgactcgat
     8221 gcgaacatta taaggctctc ccatatcttt tgaataacca gtgttgagaa cagaagtaat
     8281 ttcaagtcct gtaacatatc tcaaattaaa ttccattcca tattttgaaa gaacactctg
     8341 tttcacaatg ccgtctttta aaatataagt gaagtcctct tcgagacttt caaaagtcaa
     8401 gtacttgtga taactttttt caatgatagg aaagttatga ttatcaatat accgttgcaa
     8461 aatgtgatga ttcacgcttt tctccaaata ttcttttacc aatgtataat ttgtatcttc
     8521 aagagaaatt aacatttgct aatgcccttt gatagtaaca cttatattat accattgaaa
     8581 tatattatat tctgcttttt ttgtaaaatg tttatgaaaa tagagaggag ttcattttca
     8641 atggaagaaa aattgtttaa caaacatttt gtggccatca cagtaataaa ctttatagtc
     8701 tatatggtct actatctttt tacggttatt attgcctttg tggcgactag agagctagga
     8761 gctcagacta gccaggcagg attggcaaca gggatttata ttctagggac tttattagcc
     8821 cgtttgattt ttggaaagca gttggaggtg tttggtcgtc gtttggtttt aagaggaggt
     8881 gctatttttt acctcttaac gaccttagcc tacttttata tgccaacgat tagcatgatg
     8941 tacttggttc gtttcttgaa cggatttggt tatggtgtag tatcaactgc gacaaatacc
     9001 attgtaacag cctatattcc agctcgtaaa agaggagaag gaattaattt ttatggcttg
     9061 tcaaccagtc tagcagcagc tattggccct tttgtaggaa cctttatgtt ggataatctt
     9121 catattgatt ttcgcatgat tattgtctta tgtagcgtct tgattgggtg tgtggttgtt
     9181 ggtgcttttg cttttccagt caaaaacatg tctttaaatg cggagcaatt ggctaaaacc
     9241 aaatcgtgga ctgtggatag tttcattgag aaaaaagcct tgtttatcac tgcaatcgcc
     9301 tttttaatgg ggattgccta tgcttcagtt ttaggatttc aaaaattata cacgtctgaa
     9361 attcatttga caacagtagg cgcttatttc tttgtggtct atgccttaat cattaccatc
     9421 actcgtccag caatgggacg tttaatggat gctaaaggcg ataaatgggt cttgtaccca
     9481 agttatcttt ttttagcaat gggactcttc ttgctaggta gtgtatcgtc tggaggaagc
     9541 tatttgcttt caggagcctt gattggcttt ggttatggca cttttatgtc ttgtggtcaa
     9601 gccgcctcca tacaaggagt ggatgagcac cgctttaata cggctatgtc tacttatatg
     9661 attggtcttg atttaggttt aggtgctggg ccttacctct tgggcttgat taaagatttg
     9721 gcacttggta gtggtgtggc ttcctttagg cacttattct ggttagctgc tgtgattcca
     9781 ctgatttgta ccttgcttta cttgttaaaa acaaagacaa gacaggttgt gtcttaagga
     9841 caagaaaagg agtttagtct tatacttaaa tacaaacgta tcttaacagc tgtagatagt
     9901 tcctatgagc cgggattagc tgtgggtaaa gccactacta tagcgctttg aaataattct
     9961 agtttgctat tggtacatgt caataaaaat gactcgcaaa agccattcgt gaaagagaaa
    10021 atgtggcctt atttttagta ggtacaattg gattaagcac gtttagatac atgacaattg
    10081 gattaacatc agaatatagg ctttgtcatg ttaagattga tctgttgata gtgagagcta
    10141 ataaaaaatg ttataatact atgaaataaa gtgataaaga taaggccttt tatgttcctt
    10201 ttctttaccg cttttattat tgtgtgaaaa taacacttaa tgatcatttt atttattatt
    10261 ttattacctt tacattcatc aataagcctg ttaaaatggt atttgttata ttttattatt
    10321 tggaggaaac cagaaaacat ggaaatgaca tggactgtga aatacatcac agaatttatc
    10381 gcaacggctt ttttgattat tttgggaaat ggagctgttg ctaacgtcga cttaaaagga
    10441 acaaaaggac ataactcagg ttggttagtg attgcttttg gctatggctt aggagttatg
    10501 atgccagctt tgatgtttgg taatgtatct ggaaaccata ttaatcctgc tttcacagtt
    10561 ggactagcag tatcaggctt gttcccatgg gctcacgtct tacaatacgt tgtggcacaa
    10621 ttacttggag ctatctttgg tcagttggta gtggtaatgg tttataaacc ttactttatg
    10681 aaaactgaaa atccaaatca tgttttaggc tcattctcaa cgatttcatc tcttgataat
    10741 ggtcaaaaag acagccataa agcctcttat atcaatggtt tcttaaacga atttgtaggt
    10801 tcatttgttc ttttctttgg tgctttggct ttgactaaaa actactttgg ggtagagtta
    10861 gttggtaaat tgattgaagc aggctacgac caaacaactg cagcaacaca aatttcacca
    10921 tacgtgacag gctcattggc ggttgctcac attggtattg gtttcttagt tatggtcttg
    10981 gttacttcat taggtggacc aactgggcca gcactaaacc cagcgcgtga ttttgggcct
    11041 cgtttgttac accacttctt accaaaatca gttcttggtc aagccaaagg tgattcaaaa
    11101 tggtggtatg catgggttcc tgtagttgca cctatcttag cggcgatagt agccgtagca
    11161 gcgtttaaat acctttatat cagataaaaa aagaactaaa gcttctttta gactcaagac
    11221 aagctcgctt aaggaacttg tcttttttat atgagttaag cgaaatctaa tgcaaacttg
    11281 actgtcttgt atagcgtatt ttgtaaattt tattagactt cttgtaaaaa gcctctcctc
    11341 agataagatg actaatgcct ctaaacggtg ttacaaataa acgaggcatt cctaacttcc
    11401 tttatctggt gttgaaacta ttttgcacgg actaaatcac tgacagagta aaaaacgatt
    11461 tttcattttt gttgtaaaat attaaaaacg tctctggtta gtgattccca gaaacgttat
    11521 cttatctatt tgtttgttgc ttatgagagg taaaggagga acgaatcagc attccaccag
    11581 tgaagaaaac gatagcgatg accagaagtt tcaagctatt aatatctaaa tttgttaaga
    11641 aaaacacagc tagtaaaacg ccaataatac caccagaaac aattccagca aaaccatccc
    11701 aactgacacg gtttgctttg ataaactggc tactagaagc tgtcataatc atagctgcat
    11761 ctagcatcat aacaggcata gcaactgttg ggctaagacc cattaatgaa aagaaaatca
    11821 attctggagc ataattgcct aaccccatag tcatcaagac tccaacgata aaattaaaac
    11881 caattccaac aaaaagccag atgccatgga ggccatgaat ggtgtctgaa aggtgttctc
    11941 ctggatggta aattattcta atgatcatga ttatagctgc tatgattaaa agactaccaa
    12001 gaattcgttg gacagttgga gcatgccagt tttttgtaat atgagtccca aaataagctc
    12061 caataaaggc tgctgcagcc atagcaagta aagttagaac ctcaactttt acgacaaaaa
    12121 taaagcaaag agattgaatg agcaccggaa gcacatgagc tacggtcata gtgccaggca
    12181 attgtctatc gtcagtgact aatttagtta acttaaagca cgttgtggta gtagcaaaag
    12241 accctatccc aagggtgtca agggcatctg ttagcaggcc aatccaaaac cccgtccaaa
    12301 agcgtttaaa aggattgatc ttattttttt taagatgttt tactaacata aagaaaataa
    12361 aaagcattgc cgaaactagc aaagtttgta tcagtctaag gataagcatt tcgttcataa
    12421 agactagttt acaaaaaaaa accttagccg tcaacgtgat ttacttcatt aaaacatgcc
    12481 actatgcttg gaagagcttt ggttcgatgt attttgttaa aattaagcta aaatattaat
    12541 attgcatgaa aggggacgcc ttcctttttc ccttactgag cttagctgtt attgtagtga
    12601 atgtttaaaa ggctagtttg tcgctcttta tcaaaaatct agtaggatga atacgtataa
    12661 tttcttgtca aatagaggaa ttttgtctat aatagcagag gattaggagg aaattatgac
    12721 tttaatggaa aatattacct ttaaaactcc agtattacgc gttaatgatc gcgaccttaa
    12781 tattgcattt tatcaaaata atttagggct tcgtttagta tctgaagaaa atgcgattgc
    12841 tatcttttca tcttggggag aagggcagga atgttttgta attgaagagt caccttcagt
    12901 tagaacgcgt gcggtagaag gccctaaaaa ggttaatacg attgtcatca aaacaaatca
    12961 acctaaagaa atcgaacaat tattagctca tggagcacat tatgatactc tttttaaagg
    13021 tcaaaatggc tatgcctttg agactatttc cccagaagga gaccgattct tgttgcatgc
    13081 tgaacaagat attaaacatc tccaaggtac tgatttacca tcgcttgaaa aagatgcgac
    13141 ttttaaaggt ttaactcaat ttaaatttga tattattgtt ttaaatgtta ttagtgaaga
    13201 acgctcaaaa gctttttatc gggatctgtt tagtgatcag ttacctatta ctatggattt
    13261 tattcaagaa gaaggtcccg atttggcaat tgatccccat attgcttggg atttagaaat
    13321 tttagaattt caagtctcaa aggactatga tatgaaggtc ctaaaagcaa ctttagaaga
    13381 agacgggcac aaggtctaca ttgataaaaa acacaaagta ttggtccttt ctgatccaag
    13441 tcagatcgaa gtatggttta cgaaatgact ttggcagtca ttaaatgtat tgaaaaccat
    13501 cttcacaaaa aagtatacaa aggggccagt ctggctctct ttcaatctgg tcgatggcaa
    13561 gaataccata tcggaacaat tgatggaaga cgaccagttg atgctaactt agtttatgac
    13621 ttggctagtg tttcaaaagt tgttggtgtg gccacaatat gcaatatttt attgaataat
    13681 ggtacgttag cattagatga tcccttaaag gtatattatc ctagtattgc tgatgcgact
    13741 gtcactattc gacagttatt gactcatacc agtggtcttg atccttatat tcctaacaga
    13801 gatgttttaa atgcacaaca attaagaaaa gcacttaatc atcttactca aaaagaaaat
    13861 aaaaactttt attacacaga tgtcaatttc ctcttgttag gctttatgtt agaagagctc
    13921 tttagtgaat ctttagacca gatatttgac aagactatct ttactccctt tgggatgtat
    13981 catacgtctt ttggccctcg tccagaagct gtaccaacat taaagggtgt gagtgatgga
    14041 gaagttcatg atcccaaagc aaaaatctta aaaaaacatt ctggatctgc ggggctattt
    14101 tcaactcttg cagatttaga aagttttagc aatcattatc ttaatgatcc attttcagat
    14161 tgtctgtggc gcaactacag ccaacaaaca attgagcggt cactagggtg gaatttagat
    14221 ggcgattgga ttagtcatac aggttacaca gggccatttc taatgcttaa taaaaaagat
    14281 caaacggcag ctattttttt gaccaaccgt acttacgacg aggatgataa aagtaaatgg
    14341 ttaaaagaac gtcagttgct ttacaatgca ctaaagcatg atctgacaac ccccgtatcg
    14401 taacgtctaa aggggcagtt ttagtgatct tattgctgtt tttaaagttt cttctaaaaa
    14461 atagccattt catttgtctg atgcgattag agtgattata agtgaaaaaa gaatagccat
    14521 ctcattttga atcaaatgag atggctattc ttttttataa gttattgatc atttagatac
    14581 tactatttac ttgaaatagc ttcagcagca tcgtccatgg aaagcacttc gtggaagaca
    14641 cgttgtgtca actcagtttt ttgttctggt gtaaggtatt tggtgttgac acagtaacca
    14701 gagatacgta cgataacgtc ttcgccgttc atgattttgt cataaacatc gttaaggtcc
    14761 ataacgttca agttaacgtg ctgaccacca ttttcaaagt aaccgtcaag cactgttacc
    14821 aagttgtcaa cttgttcgtc aaatgtttta ccaagagcac gaggtgatac ttgagtagtc
    14881 aatgagatac catcgttagc atgtgagaat tccagtttag caagtgagtt aaggttttgt
    14941 aaccagccac cttttgcttt gttagatggg ttagcacctg gtgagaagaa ttccacttgg
    15001 ctagtgttaa ctgtaccatc ttcgttcaag aagacgccgc ggtgaactgg agagttacca
    15061 gtttgtttag agtaagcaac gtttgaagtg atggtaagaa gtgatactga agcctcagca
    15121 ttcttgtaaa gtttgtggct tgcaagacgt gtgtggtaag cttccatcaa ccatttcgcg
    15181 atgtcatcaa cacggtcgtc atcttcaccg tagcgaggga agtcacctgt tacttcgtag
    15241 tcatagatgt agccattttc atcgcggata gttttaacag ttgcgtattt aatagctgac
    15301 aaggtatcaa ctgtgttagc gaaaccacag ataccgaatc ccatgttagc acgttggtgt
    15361 gttggcaaga aggccatttg aactgcttcg tagttgtatt tatcagtcat gtagtggatg
    15421 atgttaagcg catctacata agtatctgtc aaccagtcaa gagatttctc aaagttagcc
    15481 ataacttcgt cgtactcaag gacttctgat gtgattggtt caacaacgtt aaacactttg
    15541 tagtctctgt gaacatcatc gtaaccaccg ttaagaccag taagaagggc tttaagaacg
    15601 tttacacgag caccgaagta ttggatgtta tgacgttgtt cttcattttc tgggtcaagt
    15661 ggtgatacac aacatgaaat acatgacatt tcaccataac cttctttagc cattgttgtc
    15721 acaccttcat attggataga agagtgtttg tggctcattt tcatacagta gcgacggaat
    15781 gtttctggca gttggtcagt ccaaagaact gttaagtttg gttctggaga gttaccgata
    15841 ttatcaagag tgtttaagaa acggtagtcc atcttagtca cacggtgacg accgtcgtta
    15901 cccataccag ccatagaagt tgtgatgaat gttgggtcac ctgagtaaag ggcatcgtaa
    15961 gctttagtac gaccaaattt tacggtacgg agtttaagga caaaatcatc aacaaattct
    16021 tggatttctg attctgtaaa ggtaccgcga gcaaggtcac gttctgcaaa gatatcaaga
    16081 acgattggca cacgtccaag agaagtagca gcaccgttga tcacacgaca tacagccatg
    16141 aaagcgatgt ttacccattg gatagcttct ttaacgtttt gtgctgggcg acgaacatca
    16201 actccgtaaa ggtcaccaag tttaaccact tcaccaagag cttggtattg aaggttaact
    16261 tcttcgcgaa gacgaatgga ttcttcatcg atttcagtga tagcattcca gtcattgact
    16321 ttttcttgca tcaagtagtc agcaccgtaa agagcaagac gagcgtaaac accgatgata
    16381 cgtccacgtg agtaagcatc tggaagacca gttacagtgt gggcatgacg agcgcgacga
    16441 atatttgaag tataagcgcg gaagataccg tcgttaacag ttgtcacata cttagtaaag
    16501 atttcatgta ctgctgggtc tggttcatag ccgttttctt taagggtcgt ttccgccata
    16561 cggataccac cttttggcat gaagttcaat ttgaacaatt catcgttttg aataccataa
    16621 attaattcat tttctttatc gatgaaacca gcaggaatgt cagcaattga agttggacga
    16681 gtatcgtatg ggaaacgtgt agcttcatag tgtgcttttg tttcttcgat aacttttttg
    16741 atgtgaagtg agcgttcagt agcaccagcc aagaaagatt cgtcgccatc gtatggggtg
    16801 tagttagctt gtacaaaacg tgagacactt gctttttctt tccagtcagt tcctttaaag
    16861 ccttcccaag ctttttcgaa aacatctgta ttggttttaa cagttgccat aaatttctcc
    16921 ttaaattcta gtaacaaagc gatctgttac atttacaatt ctaagtttaa cacataggaa
    16981 acgttttccc aagcaaaatt cttgacaaaa ttaagattct tttataatac agattgttga
    17041 aacagtcaca aactgtatta gaatgtattt ttttggcttt agatagccta aaaggtataa
    17101 tagagaaagg agggacttat gcttattttt ccactgatta atgacacgtc acgaaaaatc
    17161 atccatattg acatggatgc cttttttgct gcagttgagg aaagggataa ccctgcttta
    17221 aaaggaaagc ctgttgtgat tgggaaagat ccaagagaaa caggtggtcg cggagttgtt
    17281 tccacttgta attacgaagc gagaaaatat ggcattcatt cggccatgag ctctaaggaa
    17341 gcttatgagc gttgtcccaa agccattttt atttcaggaa attatgaaaa gtatcgaaca
    17401 gttggagacc agatccgccg tatttttaag cgttatactg atgtggttga acctatgtct
    17461 attgacgagg cttaccttga tgtgactgat aataagttgg ggattaagtc agctgtgaaa
    17521 atcgctaaac tgattcagca tgatatctgg aaagaagtag gattgacctg ttcagcaggt
    17581 gtgtcttata acaaattttt ggctaaattg gctagtgatt ttgaaaaacc tcatggcctc
    17641 accctagtct tgaaagaaga tgccctgtgc tttttagcca aactccccat tgaaaagttt
    17701 catggtgttg gtaaaaaatc agttgaaaaa ctgcatgaca tggggattta tacaggacag
    17761 gatttgttgg cagttcctga aatgaccttg attgatcatt ttggtcggtt tggttttgac
    17821 ctttaccgta aagcgagagg catcagcaat tctcctgtca agtctgatcg gatacgcaag
    17881 tcaattggca gtgagagaac ctacgctaaa ctgctttatc aagaaacaga catcaaggca
    17941 gagatcagta aaaatgctaa gcgcgtggcc gctctcttac aagaccataa aaagttaggc
    18001 aagaccattg tgctcaaagt gcgttatgct gattttacca ccttgacaaa acgtgtcacc
    18061 ttgccagaat taaccagaaa tgccgcacaa attgagcaag tagctgggga tatttttgac
    18121 agcttaagcg aaaatcctgc tggtatccgc ctgttagggg taaccatgac caatttggag
    18181 gataaggtag ctgatatttc cttggaccta taggagaaag agggctctat ccgtccgcct
    18241 cattttggac caaagaagct gattagggat ttccctaatc agcttctttg gtccattatt
    18301 ttattacagc atagcatcac ctttttcgtt aagggtttta gccttgtaaa aagcaaagcc
    18361 ataaagagca gcttgtataa ggataaggat agttccaacc attgacaagg ttgttgtgaa
    18421 ctggttaacc aagccgataa cagaaagggt aagccctaag atgtaaggaa tataactaac
    18481 cgttaatcct tgttttagtt tggataagtt ttgagcacaa aagacaatga tagcaataat
    18541 agcaaggaca tttaagacag ataagaaaat cataaatggt gtcatgctgc tttgtagctg
    18601 tgccaattgc tcagttgtta attgggcccg aaatgcttca ttcttgagtt ggctttgtaa
    18661 gtagaaaatc cctgcaaatc ccattaatga ccgtacaact ccaagcccgt ttagaataat
    18721 aatggcaata gtagacgttt tgagtgcctg acgcactttt tcataagaaa tcatataatc
    18781 ctcctagagt ccttaatccg aaattgtaca atgtgtctaa tacaaaaata ttataccata
    18841 gattaatcaa aaatgtccgt ttttctagga ttttttctgg aaaaagaggg caacatctga
    18901 ctctgtaagc cctatcatcg aatcgatagt cgaataattc tcaggtgtta acctaaaatc
    18961 atcattatct gactgagagt tctcagtggg gttagagttt gttgattgag aggaagattt
    19021 ttgagagtcg tcctcaaggg ttgccgtatt agaaaaaagg gaggtctgct cttttgattt
    19081 tagctcttgg ttaggttgag aggaggctaa gtcggattgt tcttggaagc gttcgatcaa
    19141 gtaggtttgg cgtttatcgc cttcgtgttt aatagcatac tcaaaggcag tatattctcc
    19201 caacagaatt aacttacttt tagaccgagt aatggccgtg taaatcacat ttcgttgcaa
    19261 gagtcggccg ctttggcgtg tgataggtaa aatcaccact tgaaactcac tcccttgcga
    19321 tttatgaatg ctcatggcat aggccagggt taattttagc cattcatttc tagggtacgt
    19381 gacttcgcta ccgtcaaaat ctaagattaa ttcgtcttgc ttagattcgg tgtatttagc
    19441 aggaatcaaa tctgtaatat aaccaatatc tccgttaaag acattcaact gagcatcgtt
    19501 gactaagtgc aggactttat cacctttacg aaaatacgta tcattgaaca gaaattctgt
    19561 ttgtccttgc aagggattga gaagttcttg catgagttga ttaagatgat tgatgccagc
    19621 ttgtcctttg tacataggcg ctaaaatttg aatttcctca gcagggatgc cacttttaat
    19681 agcagatagg acaatttttt gaatcatgtc agggataaag gctgcttggg cttcaaaata
    19741 agaacggtca gcttttttat cacgaaagtc agcagctaag attcctcgac gcatctgatc
    19801 tgccaaattg acaatagtag attcttggga ttgacgaaat atcttttgca aggcgatttg
    19861 gggcaggcta ttgactttta aaagatctga caggacttga ccgggtccaa ccgaaggaag
    19921 ctggtcacta tctccgacaa taatcacttg agttgttgag ttaatagctc ctaacaactg
    19981 gttggcaagc caggtatcca ccattgaaaa ttcatcgaca atcagcaagt cgcagtctag
    20041 ataatcctcc atggcttggt aatcgttgtc gccattgagg cctaagtgcc tgtggatggt
    20101 tgcgctagga agtccagtca actcattcat gcgacgtgca gctcgacctg ttggagctgc
    20161 taacaagata ggaaggtctt ttttatccaa atcaatctga tgcaggttcg cgtaagcctg
    20221 caaaatgcct cgaataacag ttgtttttcc tgttccggga ccacctgtta ggagaaagac
    20281 cttgctggtt aaggccttag taatggcttc ttgctgcact tggtcatagg tgatggcaaa
    20341 gtctttttga acggcttgga tggttgtttg aatggtatca tgactaaatg actgacttaa
    20401 aggggtatct aagagacgag agatgttgtt agcaatccct tcttcagcaa aataaaggct
    20461 agcatcaaac agtttggtgt cactgttttt gattttgccc tctatgatca actcgcttag
    20521 ctgttcagcc acagcagcag gatcacattc tacttgacgt gcatcttcaa ggagtgtaat
    20581 ggtaaagtct aataattgtc gtgcttggac ataagtatct cctcgattga tggattcttc
    20641 caagagacag tgaaggaggg ctgcacgaaa acgtttcgga gagtcgcttt caatccctaa
    20701 gttttcagcg agagcatctg ccattttaaa cccaaaacct tgtagatctt cgactaactg
    20761 atagggattt tctttaacaa ggtcaagagc ctcttcttta tacttttcaa acgcttgaag
    20821 ggcaaaacgg ttgctaaggc caagttcgac gagaccagca atcagttgct ctgtgccgta
    20881 attcaatttt agtttagcga caaaggcttg acgattagcc ttagataggc cagagatagt
    20941 ttctaatttg cttgggtctt ctaaaatatg gtcaatggta ttatgaccat atagcgcaat
    21001 gattttctcc gctgtttttt taccaatccc cttaaaatgg tcgctagaga aataattaac
    21061 caaaccagat gaactaggtt tgattttttg gtaacggctt agtttgagtt gctgtccata
    21121 tttagggtgc tgggtcaatt ctccccaaaa ggtgtagtca tctccttcaa taatgtcagc
    21181 catcgttcct gtgataatga tttcaaagtc gtcaatgtca ctgtctgtat cctcaatggc
    21241 aaggaggaga atcttaaaga aattagcctg gttttcaaaa atgatacgat caacagtacc
    21301 tgtaaaaacg tattccatag taactctttc tatttataca agataactga aaacctgccc
    21361 aaaggcaggt tttttctaat taaagacggt cattttattg agtggccaaa aacgagcttt
    21421 cacttcaccg ataaggtttt cttttttgaa actaccaact tcgcgactat ccctggaaac
    21481 aatacgatca tcaccaagaa gaaggtattc tccttttgga acactcatct caaagcgtgt
    21541 ttgtccctca gaattagttg taaaagcatc agatgtttct gctaactgtt ggaatagggt
    21601 attataggcg taagtttttt ggagtttatc gtttttaaat tgttttagat actcagccaa
    21661 atacggctca actgtttttt taccattaat ataaagtgtg tcatcattat aagaaatggt
    21721 atcgcctggc aatccaataa ctctttttac gatttctttc ttttgtccgt tttcttcttc
    21781 ctgagcaact acaatatcaa agcgatcaat cctagcttga ttaaaaacga taaggcgttc
    21841 gccatgagct agagttgggt ccatagaatg gccgtctact ttaacagcct gccacaaaaa
    21901 aagacgagat agaccaaaga gaattaaaaa gagagtgaat gggccccatt ctttaataaa
    21961 ctgtttcata tgattccttt tatttagtga gaagcgcttg cgctttgtga gtgttggcga
    22021 agtgaagttt agcactatat tctaagctag acataccata agcggctaag agttggctag
    22081 caactttatc tgaagctgaa ccagcaccgc ttgggagttg gtaacctaaa tcttgaccta
    22141 attgatcgag attgtctaaa aatagatttc tagcaatgat agagctaaca gccacagcca
    22201 aatagtgact ttctgccttt tcttgaaagg ttagaggatt cgggaaatgg tttttttcct
    22261 tttttagatg cttttcataa tttgattggc tagtgaaagc atcaataaca atttgtttag
    22321 gttgaatgcc tttttgtaac aacaaaaaaa tagcttggtt atgaagagca actttgatag
    22381 aaatggcatt atatggttta cttttaccaa ccaattcgtt atatttttta ggtgatagga
    22441 gaagtgattg atgaggtatt tgtttctcta acagaggcgc aatctgttga atggttttat
    22501 ccgataattt tttagaatca tcaaccccaa gctttttcag gaaggaatga tctttaggat
    22561 cgacaaaact tgccacaaca gcaatcccac caaaataaga gccattaccc acctcatcac
    22621 tgccgattat aggtatatct tggctattgt tgcttgcttc aaaaactgtc ttagctactg
    22681 gaagattaag ctcttgagct aaagcatttg caccgtttcc ctggagaact aattttccgg
    22741 atttgtacag caaaacagta accccatttt ttttagcagc aaaggctaca taggtatttt
    22801 ggctactgat ggtgtagggg gccagctgtt tttttaaatg tttactcagt atagcatcta
    22861 ttttcaaaac taaggtattc ataataatta ttttaacata aaatagttga ctatggttaa
    22921 ttcataagtt tatttaacaa agaaaacaga gactcgaatg tttagacggg ttagggcaat
    22981 ggtgttgact attttacgaa agtttcattt tacggtataa tgctaacgag gtgaccctat
    23041 gaaaagtatt aatcgctata aattcacctt tggtgaaaaa acattaacat tgacaactga
    23101 caaagacaat ctctttatgg aagaagttga gcgggtagct aaagaaaagt atcaggctct
    23161 taaaaatcat ttaccagaag ctgatgacga gacaatcgct attttaatgg ctatcaatac
    23221 cttgtcaaca caattaagca gagagattgc cattgaaaaa atggaagctg aaattttaga
    23281 tttacgtcaa aaaaccttgg ttggtcttca agaaaaagct aatcaaatag atgtgaatga
    23341 ggtttaatca tgttatcttt attgatagtg cttgttttaa cttggaattt ttatattggt
    23401 tatagtagag gtattattct tcaatcgttt tatgtcttag gagccctact ttcttttttg
    23461 gtagctaatc gattttatat tggattagcc cataagctaa cgctttggat tccttattct
    23521 aacccggtag aaggaacatc agtctttttc tttaaatcag ttgatatctt tgttttagat
    23581 aaggtttatt atgcaggcct tgcctttttt atcattttct tattggggta tgcattgagt
    23641 cgctttcttg ggatttttgt tcatttcctt ttgctagatt attttgataa ccagtggaca
    23701 aaatgtttga gtggcggact agcgcttcta gtatcgcttc tttttttgaa catgttactg
    23761 tctatttttg caacggtccc tatgcctttt ttacagcact atttgcactc tagttttctt
    23821 gctcgtttgg tgatcgaaca ccttccacca ttgacaataa ttattcaaaa attgtggatt
    23881 caagccatta tttgatatcg ttttgtgact aatataagaa cctggagtga gtttcacctt
    23941 taggttcttt atttacgaga aactgtttag aaataaagag aacgcatggg aacttagtga
    24001 ctttcttgcc ccattttcca tcattttagg tataatgaag agtatgaata acaagatttt
    24061 agagcagtta gaatttaaca aagttaagga attgctatta ccttatctca agacagaaca
    24121 atcacaagaa gaattattag agctggagcc gatgacggag gctcctaaaa tagaaaaaag
    24181 ttttaatgaa atttctgaca tggaacagat ttttgttgaa catcactcat ttggcatagt
    24241 cagcctaagt tcaatctctg agagtttaaa acgcttagag ctttcaactg atcttaatat
    24301 tcaagaactt ttggctatca aaaaagtttt acagagttct tcggatatga ttcactttta
    24361 ttctgatttg gataatgttt ctttccaatc tttggatcgt ttgtttgaaa atttggaaca
    24421 attccctaat ctgcaagggt cttttcaagc tatcaatgat ggtggttttt tagaacattt
    24481 tgcgagtcca gaattagagc gtatccgtcg tcaattaaca aatagtgaac gacgggttcg
    24541 tcagatttta caggatatgc ttaaggaaaa agcagagctt ttatcagaga atctaatcgc
    24601 tagtcgtagt ggacgaagtg tcctaccagt aaaaaatact tatcggaatc gtatttctgg
    24661 tgtggttcat gacatctctt cttcaggaag tactgtttat attgagcctc gtgctgtagt
    24721 tacactaaac gaagagataa cgcagcttag agctgacgaa caccacgaag aaggtcgtat
    24781 tttacacaca ttttcagact tgttaagacc tcatgtcgcc actattagaa ataatgcatg
    24841 gattcttggg catcttgatt ttgtaagggc taaatatctt tttatgtctg ataataaggc
    24901 gacgatacct aagatctctg atgacagcac gttagcatta atcaatgttc gtcatcctct
    24961 tttaagtaac cctgtggcta atgacttaca ttttgatcaa gatttaactg caattgtcat
    25021 cactggtccc aatactggtg gtaagacgat tatgctaaaa acactcggtt tagcacaatt
    25081 aatgggacag tctggtttgc cagtattagc ggataaaggt agtaaaattg cagtatttaa
    25141 caatatcttt gcagatattg gcgatgagca atctattgaa caaagtctat caactttttc
    25201 tagtcatatg acgcatatag tcagtatttt aaacgaggct gaccacaata gtttagttct
    25261 cttcgatgaa ctgggagcag gaacggatcc tcaagaaggt gctagtttgg ctatggctat
    25321 tttagaacac cttaggttaa gtaatatcaa aacgatggcg accacgcact atccagaatt
    25381 aaaagcttat gggattgaga caaattttgt agagaatgcg agcatggaat ttgatgccga
    25441 aacgcttagc cctacgtatc gctttatgca aggagttcct ggacgatcaa atgcatttga
    25501 aattgcttct cgccttggtt tagctccatt tattgttaaa caagctaagc agatgacaga
    25561 ttctgactca gatgttaacc gtattattga acagttagag gcacagacac ttgagacacg
    25621 tagaagactg gatcatatta aagaagttga acaagaaaac ctcaaattca atcgtgcggt
    25681 taagaaactc tataatgaat tttcacatga gcgcgataaa gagttagaaa aaatctatca
    25741 agaagctcaa gaaattgtag atatggcttt gaatgagagt gatactatct taaaaaaact
    25801 caatgataag agtcaattaa aacctcacga aattatagat gctaaggcac aaataaaaaa
    25861 attagcacct caagttgatt tatcaaaaaa taaagtctta aataaggcta aaaaaattaa
    25921 agcagctcgt gcccctagaa ttggtgatga tattatagtg actagctatg gacagcgagg
    25981 tactttaact agtcaattaa aagatggccg ttgggaagca caagtgggaa ttatcaaaat
    26041 gacattaaca caagatgaat ttacccttgt tagagtccaa gaagaacaga aagtcaaaag
    26101 taaacagatt aatgtggtta aaaaggctga tagttctgga ccaagagctc gacttgatct
    26161 tagaggtaaa agatacgaag aagctatgca agagttagat cattttattg atcaagcatt
    26221 gcttaacaat atgggacaag ttgatatcat tcatggtatt ggtacaggcg ttatccgtga
    26281 gggagtgaca aaatatcttc gtcgtaataa gcacgttaag cattttgctt atgccccaca
    26341 aaatgcaggg ggatctggcg ccacaattgt aacgttaggg taaattatgg aatcatatga
    26401 acaattttat gccaaactat ctcaaccttt tagaaaatcc ccacagttaa taattctttt
    26461 aaatttttta ctaaaaatag tcacaggaat gatgtacata ctctatccat cttttctgat
    26521 atttactctt tggcaaggga tgacatttca attatggtta aggctattaa ttatccctgc
    26581 tgttggcttt atagctttgt cttacattag gaaacgcttt gattgtccac gaccgtatga
    26641 aaaatggaat attaaacctt taattgataa ggatacaaag ggaaggtcaa tgcctagcag
    26701 acatgttttt tcagctacga tgattagtat gtgtttgtta cgatattatg tttactttgg
    26761 aatagtttgt ttaatattat cggttctatt ggcaatttgc cgtgtgatag caggtattca
    26821 ctatcctaag gatgttattg taggttacct tattggcttg atgttagggc tttgtttatt
    26881 gatttagcga gttcgtagca aatagtttca aaaacaacta aattcttgta caataggctt
    26941 atcattaaga tgaaatggag aaaaaagatg gcattagaag taacagatgc tacatttgta
    27001 gaagaaacta aagaaggttt agtactcatt gatttttggg caacctggtg tggtccatgt
    27061 cgtatgcaag caccaatctt agaacagtta tctcaagaaa tcgatgaaga tgaactcaaa
    27121 attttgaaaa tggatgttga tgaaaatccg gaaactgctc gtcagtttgg tattatgtca
    27181 attccaacat tgatgtttaa aaaagacgga gaagtggtta aacaagttgc aggtgttcat
    27241 actaaagacc aactgaaagc tattattgct gaattgagtt aaataaaata aagcccagtg
    27301 tcacgctgag ctttatttta ttatctacta acttaaatgg aataaccatg taaaaataaa
    27361 acgacttgca aaaaaggtgg caacagtaat gaggaaaaat acagtgacaa taaggggttt
    27421 ctgataagga agttttgctc tttcttcccg tttttcgatt tcgtctaata attttccact
    27481 tgaaacagct aggatttcct tataagtttg cacatcatat tttttcttaa aacgttccac
    27541 acgattagca taagtcatag taattatcga taataaaaca aaaatgccaa gtcctagcca
    27601 ctctaagaaa tagactaatg gataacttga aatcattaat agtatcatca atgttaccat
    27661 tactttggta tctcgttcaa aattcttttt atcaacctga gtgatggtat atttcatttt
    27721 ctcaatgtct cctttaatta gttggtctaa gctcacttga aaaatttgac ttaggagtaa
    27781 gaggctatgg atgtctgggt aagttttgtc attttcccag ttagatatgc tctgacggct
    27841 tacatagact ttctcggcta attcttcttg cgagagcgct tgttgtttac ggtagcgaat
    27901 aatttgctga ccaatttcca taaatatctc ctttcataat attagtataa ggatgataag
    27961 ctaacgggtc tatcaaatgt atttgacatt agggatagac cactatttat agggtattaa
    28021 aagataatct gaggaaaact ttacagcggc gtaaaggaat tgtaaacaaa aagtgaaccg
    28081 ttatagttca cttgcgatta agcatttttc tgttttaagt aggtctctag cattttcttt
    28141 tgtggtgttg caaagggata cagagaaaag tcctcaattg ctacccactt taggtgagga
    28201 gcattaggta aatctgttgc tttgaccacc ccctctatga gttctattgt ccacttctgg
    28261 tgactaaaag tgtgcttaat atttggaaag tgattatcag tccattgggg ctttaattga
    28321 tattctcttt cgaaagtttc attttgggtt tgccagatta tggggttgga ttgattgtca
    28381 tcaaataaat ctaattgttg agaaagaggt gacgtttcga taataggaaa tgaccaaaac
    28441 cctcctagaa gtctcccttt agtatttttc tccagtagat attgtccatt ttggttacga
    28501 atgacaaaag cctgaattcg cattggttta ggctttttct ttggattttt tatggggtat
    28561 ttaccataag taccattcaa ataagcagcg ttaaagaaac gaatagggct ttcatcaggc
    28621 ctaggtgtct tagcggattc gatgtctgta cctagatcca taagtgcctg gttaaaatca
    28681 ccgggtctgt cagggtcaat tagtatttcc ataatagctt gaaaaatttt acgattttta
    28741 gggtcaccga tatcataatt aacttcaaac aaacgagcca tgacacgcat cacattgcca
    28801 tcaacagcag gctctggtaa gttgaatgag atgctggcga tagcacctgc agtataagga
    28861 ccaatccctt ttaatgaagc aatatcatca taagtgtgag gaaatatgcc accaaaatca
    28921 accatcactt gctgtgcagc cttttgcata ttacgcaccc gagaataata gcctagtccc
    28981 tcccatgcct ttagtaattg ttcttcagga gcgtctgcca aatcttttat ttgaggaaac
    29041 cactctagaa aacgtttata ataagggatt accgtattaa cttgtgtttg ttgcaacatg
    29101 atttcagaaa cccaaatata gtatggatta gtagttcttc gccaagggag atcacgtttt
    29161 tcttggtcat accaccctaa aagtgtgcga cgaaaagaag cgattgtctc attatcccac
    29221 atattaatac cataatcttt taattcaatc atgttgttat tgtaacacag gagtcttaaa
    29281 aagagtaaaa aaagatttta ggtatttgcg aaaaagaaaa ggaaatatta taataatatt
    29341 aggtttacct catctaaatg ttgatttaga ataactgaaa ttaacgatag aagcagacag
    29401 gttttaattt ggaggggaca tgttccagaa attaaagaat cttattgatc ggtattcgtg
    29461 gttcgttttt ataatgatga ttcttgtgtt atttcttaac tatatttatc catttgatcc
    29521 ttctttgagc ggactacagt tggaatggct gatcatgacg caagtttttc ctggattagg
    29581 tatcgtatgt gccatggttg ctattatttt taaaaagttt aacctttttg ttttggccct
    29641 aattttatat tttgcacttt ggttaaaact tttccttgct ttttcttttt tcacctattt
    29701 tttaggagtc tgactaagtg ccaattttta aaactcgtga aagaaaatgt ttgacaaaac
    29761 ttagtcaagt agaaaaagtt ccttgctttt aattgactat tagtgtacaa taagattctg
    29821 tgagtatacc tcacttactc actccaaaag tagtgagtca ttagaccaaa aggaggaaaa
    29881 tatcaatggc taaatacgaa attctttata tcattcgtcc aaacattgaa gaagaagcta
    29941 aaaacgcttt ggtagcacgc tttgactcta tcttgactga caacggtgca actgttgttg
    30001 aatcaaaaga ttgggaaaaa cgtcgtcttg catacgaaat caacgatttc cgtgaaggac
    30061 tttaccacat cgttaacctt gaagcgactg acgcagcagc tcttaacgag tttgaccgtc
    30121 tttcaaaaat caatggtgac attcttcgtc acatgatcgt taaacttgac gcttaattcc
    30181 aactaagagg gtagtttatg attaataatg tagtactagt tggtcgtatg accaaggatg
    30241 cagaacttcg ttacacacca agtcaagtag ctgtggctac cttcacactt gctgttaacc
    30301 gtacctttaa aagccaaaat ggtgaacgcg aggcagattt cattaactgt gtgatctggc
    30361 gtcaaccggc tgaaaattta gcgaactggg ctaaaaaagg tgccttgatc ggagttacgg
    30421 gtcgtattca gacacgtaac tacgaaaacc aacaaggaca acgtgtctat gtaacagaag
    30481 ttgttgcaga taatttccaa atgttggaaa gtcgtgctac acgtgaaggt ggctcaactg
    30541 gctcatttaa tggtggtttt aacaataaca cttcatcatc aaacagttac tcagcgcctg
    30601 cacaacaaac gcctaacttt ggaagagatg atagcccatt tgggaactca aacccgatgg
    30661 atatctcaga tgacgatctt ccattctagt cagaatggat tgaacgaata cgaaattatt
    30721 tgagttcggg ctaaaaattt agaacttaga atttagatca actccctagg aaatcaagat
    30781 ttcatgccag ttttctaaaa ttcagtcgtt ttttaagagc ccttaacatc ataatttata
    30841 aaggagaaaa tacatggctc aacaacgtcg tggcggattc aaacgccgta aaaaagttga
    30901 cttcatcgca gctaacaaaa ttgaatatgt tgattacaaa gatactgagc ttcttagccg
    30961 tttcgtttca gaacgtggaa aaattcttcc tcgtcgtgta acaggaactt cagctaaaaa
    31021 ccaacgtaaa gtaacaacag caatcaaacg tgctcgcgtt atggctctta tgccttacgt
    31081 aaacgaagac taataaacaa acagtccatt tcggactgtt ttttagttga ctaggactag
    31141 tctaggcgta taggtgagtt ttttctaaaa gagagaatga tagtaaacga aaatccttgc
    31201 gtagacagca aggatgaaat gattgttatt tgttaacagg tgacatagtg ttttgaatgt
    31261 tgtatttgcg ttgtaggtaa tagcgtaaag caagggaaac accaccaata atgagcaagg
    31321 caagaggagg caactgtggg ttaagagagg ttggtaaaaa ggcagttgca gagtacaagg
    31381 caatccaaat caacatggct aatgataagg ctgcgatgat tttgaaccaa cttggacgaa
    31441 ggctcttatc ttttccgaga tgacggtaaa taaagtaata agtagcgtac atggatgctc
    31501 ctccaccaaa accaagtgcc agtaaggaaa tcaatcctgt aactgtagcg tttgtgttga
    31561 agaaggtcat gatgccattt aaaagggcaa caattccgat gaatagtaaa gaggtatcta
    31621 gccacatcaa ccaaggattg gtgtttttgt cagtttctgc tgctctttga ctagggtctt
    31681 ggctaaaaga agctgcccaa gcagtcggag tgcctaatag atttcgagcg gtgacacctt
    31741 ttttctggtt ttctagaata gctggaatgg cttcttcgag aatcagctta atatcctcat
    31801 cagacttgcc gtcttggatt aatttgttcg tagcggtgtg gataaattct tgattttttt
    31861 tggtaagttc ttgtaattcc atgggaatcc cttctttata tgggttagtt aaagtaagtc
    31921 aatggtatta gctagttgta atgaaacttt ggagctagcc gtttgacaca gagttttgtc
    31981 aggtgttaaa cgcattctgc agcttgctcc actctagaac catttttttc taataaagta
    32041 aatcacaaca aaggaactaa gtagcatagc aatcaaggta atataccaaa aagcatgttc
    32101 taggccattt agtggtaacc agttgttttg gaaattcata ccataggcgg agaaaatcac
    32161 agttggtata tctaaagcca tggtcatcaa ggccagtgtt ttcataatag tgttctggtt
    32221 gttgttgata atagaagcag tggtttcagt catggcattc aagacatttt cataaatgcc
    32281 agccatctca atggcctgtt gggtttcaat caaggtatct tctagcaaat cctcgtcctc
    32341 aatgtatttc ttgagagagc ttgttgagct ggataatttc ttgacgatgc gttcgttgaa
    32401 tttcaaggaa gcctttaagt agacaatgga tttttcaagt tccatcatgt cgataagttc
    32461 ttcatttcga gtagctgctt caagctgagc ttccaaacgt tcgctttggc gatcaatggt
    32521 cctcaaggca gtcagaaaga gctcggcgtt gcgatataga atctgaaaaa caaaacgtgt
    32581 cttcatgaag gtatagaaat ttttgacccg gcggttgtga aaatgatcga aaagggtcat
    32641 gtcatgcaga caagttgtga taacagcatt ttccgttaca ataatgccta aaggcatagt
    32701 aatatagtaa cttttattgt tacgttcttc gtatatcgga acgtctacga taattagggt
    32761 ataatcatct tctacggcaa tacgtgaggt ttcttccacg tccaaagggg cgcgcaagtc
    32821 agaaatatca atgttaaatt gatcggcgat cttcatagac tcttcttggg aagggttaac
    32881 cagtttaatc caagctcctg gctcgaatgt ttctatttct ttgaattcaa ttgccgatga
    32941 aagaaacatt tgtttcatga caagccctcc tttttgatga ttgactggta gagattgaca
    33001 tcaaaccttg ataataaagc cttctcaagg attttctgaa aaattctcaa tacttatcta
    33061 ttataccaaa attcgcaaag tttggggcaa taggttatca gaa
//
LOCUS       DATTYN010000018        32217 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.18, whole genome shotgun sequence.
ACCESSION   DATTYN010000018 DATTYN010000000
VERSION     DATTYN010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32217
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.18"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            279..1322
                     /gene="pheS"
                     /locus_tag="VB649_001102"
     CDS             279..1322
                     /gene="pheS"
                     /locus_tag="VB649_001102"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEP1670060.1"
                     /translation="MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLT
                     ELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLP
                     GRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDQRFSEQFN"
     gene            1532..3937
                     /locus_tag="VB649_001103"
     CDS             1532..3937
                     /locus_tag="VB649_001103"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEP1670061.1"
                     /translation="MLVSYKWLKELVDIDVTPAALAEKMSTTGIEVEGIEVPAEGLSK
                     LVVGHVLSCEDVPETHLHLCQVDTGDETPRQIVCGAPNVKAGIKVIVAVPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLSDSIIPKEFSDGIQILPEEAVPGDAIFKYLDLDD
                     HIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPQKNLQESDKATSEAIEVAIASDN
                     VLTYASRVVENVKVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDK
                     FEDHKIVARVARQGESLVTLDGEKRDLTTEDLVITVADKPVALAGVMGGQATEIDANS
                     QTVVLEVAVFDGKSIRKTSGRLNLRSESSSRFEKGVNYATVLEALDFAAAMLQELAEG
                     QVLSGHVQAGQLSTEPVEVSTNLDYVNVRLGTELTFEDIQTVFDQLGFGLTGDETSFT
                     VAVPRRRWDVSIPADLVEEIARIYGYDKLPTTLPEAGGTAAELTPTQALRRKVRGLAE
                     GLGLTEIISYALTTPEKAVEFAVAPSHLTELMWPMSVERSALRQNMVSGMLDTVAYNV
                     ARKQSNLALYEIGKIFEQEANPKEDLPNEVNHFAFAICGLVAQKDFQTQAQVVDFYHA
                     KGILDTLFANLNLKVQYVPTKDLANMHPGRTALILLDEQVIGFVGQVHPGTAKAYSIP
                     ETYVAELDMAALEAALPSDQTFAEITKFPAMTRDVALLLDREVSHQAIVTAIESAGVK
                     RLTSIKLFDVYEGATIQAGKKSMAYSLTFQNPNDNLTDEEVAKYMEKITKALTEQVGA
                     EVR"
     gene            4047..4424
                     /locus_tag="VB649_001104"
     CDS             4047..4424
                     /locus_tag="VB649_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HEP1670062.1"
                     /translation="MYQTKITGNRLYHTVSKGYGDSVTLFGKTDQGETPMSLLVIALS
                     SCVTMCVQGFYHRQFQQDTLAVSVEASYEEEVFELLVRIDDVLDDKKKADLLAYIGTY
                     CRVKQLLKPEVTVTITLEGLSHV"
     gene            4417..4803
                     /locus_tag="VB649_001105"
     CDS             4417..4803
                     /locus_tag="VB649_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HEP1670063.1"
                     /translation="MSDASLKTYQKQWAYQKYWVMAHSQQHYNALRELFKGNQWSEEK
                     VLTFHCLIEEAQAIPPTVKSLRTVYQHVWGYFKKVASQEEKDHFKDLDAQLETKSEEM
                     LCFLQEMTAHYQPSYLLSCRLITKGP"
     gene            4876..5952
                     /locus_tag="VB649_001106"
     CDS             4876..5952
                     /locus_tag="VB649_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670064.1"
                     /translation="MFLALNEMKQSKLRYGLIAGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDLWKADSVLLAKDADATLTLSQVSRAQENQITADKVAPLAQLNTVAWSVKNPKDA
                     DKVKVSLFGIDSTSFIRPNIVKGRLFKTNKEVVLDQSLAKEEAFAIGKDFYTSSSSQA
                     LTIVGYTQNTRFSVAPVVYMNLEAFETLKYGEPLPKDKQVVNAFITKGSLTDYPKKDF
                     QKLDIKTFITKLPGYSAQLLTFGFMISFLVIISAIIIGIFMYILTIQKAPIFGIMKAQ
                     GIGNITIAQAVLLQTFLLSALGSGLGLLGTWLTSLVLPEAVPFQSNWLVYLAILVSMV
                     CFALLGTLFSVFSIVRIDPLKAIG"
     gene            5962..6630
                     /locus_tag="VB649_001107"
     CDS             5962..6630
                     /locus_tag="VB649_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670065.1"
                     /translation="MSVLTFKQVTKTFQDGHHEINALKATDFSIEAGEFVAIIGPSGS
                     GKSTFLTIAGGLQTPSSGQLIIDGTDYTHLSEKERSRLRFKSVGFILQASNLIPFLTV
                     QQQLELVDHLTGSKEKAKANQLFDDLGIAGLKHQLPQELSGGERQRAAIARALYHDPA
                     LILADEPTASLDTEKAYEVVKLLAKESKEKNKAIIMVTHDDRMLASCDKVYHMEDGVL
                     RREK"
     gene            complement(6724..7641)
                     /locus_tag="VB649_001108"
     CDS             complement(6724..7641)
                     /locus_tag="VB649_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HEP1670066.1"
                     /translation="MKTDDLRESQQVEDRRGQSSGSFGGGGLGGGLLLQLLFSRGGWK
                     TKLVILLLLLVMGGGGLSGVLGGNPSSSNNNAYQSSQVTRTNGDKASQEQVSFVSKVF
                     ASTEDYWTKQFKDKGLTYNKPTLVLYSGATQTSCGTGQASAGPFYCPGDQKVYLDISF
                     YDELSTKYGAKGDFAMAYVIAHEVGHHIQNEIGTMEDYASARQGRSKAEANQLNVKLE
                     LQADYYAGAWANYVQGQGLLEKGDIEEAMAAAHAVGDDTLQEEAYGRAVPDSFTHGTS
                     QQRQRWFDRGYQYGDFEHGDTFSVPYNKL"
     gene            7792..11007
                     /gene="rexB"
                     /locus_tag="VB649_001109"
     CDS             7792..11007
                     /gene="rexB"
                     /locus_tag="VB649_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEP1670067.1"
                     /translation="MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKER
                     EVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDL
                     PSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQ
                     QDYNQDSPLQSFARAIKLGLLNNQLSKTVIVIDGFSRFSAEEDYLLSLLNNNCQEVII
                     GSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPIFATSNQVFKPAFSRLTQLFE
                     ATHDFSQVDWQLQKNDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGD
                     MDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKS
                     GLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQ
                     ELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFH
                     HIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLT
                     QSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELV
                     LSVSTVINETFDDLSPYLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINR
                     QDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTLDYRLSTKPLSKEVIEVCFPKGIS
                     LKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEP
                     FDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIQVIDQE
                     KNFQLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLVTYLA
                     ALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKE
                     HLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQ
                     LKAITRFEADLDMGQARRLVTLPAKEKKECFLTLMRKEGHL"
     gene            10968..14636
                     /gene="addA"
                     /locus_tag="VB649_001110"
     CDS             10968..14636
                     /gene="addA"
                     /locus_tag="VB649_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020905049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEP1670068.1"
                     /translation="MLFNINEKGGPLVISFAPFLSPEAIKHLQENERYSDQSQKRTAQ
                     QIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRE
                     RIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQF
                     RIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPAFRALVKNFSGNCKDTSAFRELVYTCY
                     SFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDATDMEDY
                     GQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTDLIPSGNDVTV
                     SKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESA
                     FEFSDIAHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFM
                     VGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENFRSQSEVLNVSNAVFSH
                     LMDESVGDVLYDEQHQLIAGSYAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSE
                     VTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKS
                     VEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKI
                     QRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFNDRFYFDFV
                     ASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQ
                     AVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGE
                     TTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYVAMTRAEKKVYFIGKASKSKSQD
                     ITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
                     QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEP
                     LLEPIGVDIIEKSSRSLSDFTLPHFSKKVKVEASHIGSALHQLMQVLPLSKPINQQTL
                     LDALREIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKLDPISQ
                     EEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPV
                     TKRYLVLMGGGKPEIVEV"
     gene            14776..15588
                     /locus_tag="VB649_001111"
     CDS             14776..15588
                     /locus_tag="VB649_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEP1670069.1"
                     /translation="MNFKKIRFGFLLCLLLYPLAACNKSEQLNHYERIKKTRKLVVAV
                     SPDYAPFEFKALVNGKDTIVGADVQLAQAIADELDVDLELSPMSFDNVLSSLQTGKAD
                     LAISGISHTKERAKVYDFSIPYYQAENAIVMRASDAKVTKNISDLNGKKVAAQKGSIE
                     EGLVKIQLPKANLISLAAMGEAINELKAGQVYAVTLETPVAAGFLAQHKDLALAPFSL
                     KTSDGDAKAVALPKNSGDLTKAVNKVIAKLDEQERYKSFIAETIALTKNTMK"
     gene            15729..15905
                     /locus_tag="VB649_001112"
     CDS             15729..15905
                     /locus_tag="VB649_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEP1670070.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(16033..16395)
                     /gene="mscL"
                     /locus_tag="VB649_001113"
     CDS             complement(16033..16395)
                     /gene="mscL"
                     /locus_tag="VB649_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEP1670071.1"
                     /translation="MVKELKAFLFRGNIIELAVAVIIGGAFGAIVTSFVNDIITPLIL
                     NPALKAANVENITQLSWNGVKYGSFLGAVINFLIIGTSLFFVVKAAEKAMPKKEKEAA
                     APTQEELLTEIRDLLAQK"
     gene            16525..18339
                     /gene="dnaG"
                     /locus_tag="VB649_001114"
     CDS             16525..18339
                     /gene="dnaG"
                     /locus_tag="VB649_001114"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEP1670072.1"
                     /translation="MGFLWGGDDLAIDKETISQVKNSVNIVDVIGEVVKLSRSGRHYL
                     GLCPFHKEKTPSFNVVEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIIADKTGM
                     SLNISPSQAVIASQHKHPNHALMTLHEDAAKFYHAVLMTTTIGQEARKYLYQRGLDDQ
                     LIEHFNIGLAPDESDYLYQALSKKYKEGQLVASGLFNLSDQSNTIYDAFRNRIMFPLS
                     DDRGHIIAFSGRIWTAADMEKRQAKYKNSRGTVLFNKSYELYHLDKARPVIAKTHEVF
                     LMEGFMDVIAAYRSGYENAVASMGTALTQEHVNHLKQVTKKVVLIYDGDDAGQHAIAK
                     SLELLKDFVVEIVRIPNKMDPDEFVQRHSPEAFADLLKQSRISSVEFFIDYLKPTNVD
                     NLQSQIVYVEKMAPLIAQSPSITAQHSYINKIADLLPNFDYFQVEQSVNALRIQDRQK
                     RQGQIAQAVSNLVTLPIPKSLTAIAKTESHLMHRLLHHDYLLNEFRHRDDFYFDTSTL
                     EILYQRLKQQGYITSYDLSEMSEEVNRAYYNVLEENLPKEVALGEIDDILSKRAKLLA
                     ERDLHKQGKKVRESSNKGDHQAALEVLEHFIAQKRKME"
     gene            18348..19457
                     /gene="rpoD"
                     /locus_tag="VB649_001115"
     CDS             18348..19457
                     /gene="rpoD"
                     /locus_tag="VB649_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEP1670073.1"
                     /translation="MTKQKEITTFNVQVAEFIRHHKKEGTAIDDDVTEKLVIPFALDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYIVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSEEEKELAVAVAKGDLMAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            19692..20030
                     /locus_tag="VB649_001116"
     CDS             19692..20030
                     /locus_tag="VB649_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEP1670074.1"
                     /translation="MSDTPKYTQDQVIAIKNRILEALETVIDPELGIDVVNLGLIYEI
                     RFNDNGYTEIDMTLTTMGCPLADLLTDYIHDALQDVPEVTKTEVKLVWYPAWTVDKMS
                     RYARIALGIR"
     gene            20169..21023
                     /gene="rfbD"
                     /locus_tag="VB649_001117"
     CDS             20169..21023
                     /gene="rfbD"
                     /locus_tag="VB649_001117"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEP1670075.1"
                     /translation="MILITGSNGQLGTELRYLLDERGVDYVAVDVAEMDITNEDKVEA
                     VFAQVKPTLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGATLVYISTD
                     YVFDGNKPVGQEWVETDRPDPKTEYGRTKRLGELAVERYAEHFYIIRTAWVFGNYGKN
                     FVFTMEQLAENHSRLTVVNDQHGRPTWTRTLAEFMCYLTENQKAFGYYHLSNDAKEDT
                     TWYDFAKEILKDKAVEVVPVDSSAFPAKAKRPLNSTMNLDKAKATGFVIPTWQEALKA
                     FYQQGLKK"
     gene            21142..22296
                     /locus_tag="VB649_001118"
     CDS             21142..22296
                     /locus_tag="VB649_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEP1670076.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFIEELISHQSSKNIRYHVACLSD
                     TKHKVHFDYKGADCFYLNPPKLGPARVIAYDMMAITYALSYSDQHQIQNPIFYVLGNT
                     VGAFIAPFVKQIHNRGGRFFINPDGLEWKRSKWSKPVQAYLKFSEKQMTRQADLVISD
                     NIGIDRYLKQVYPWSKTCFIAYGTQTQPSRLTTADSKVRAYFQTFDIREKDYYLILGR
                     FVPENNYETAIKEFMASSTKRDLVIICNHEGNAYFKQLLAETECDKDPRIKFVGTLYD
                     KELLAYIREQAYAYIHGHEVGGTNPGLLEALAHTNLNLVLGVDFNQWVAKSAALYWSK
                     QKGQLAELINQVDAGFDSDHLGKEAKAIIQEHYTWEKIVGEYEALFLNEH"
     gene            22286..23218
                     /locus_tag="VB649_001119"
     CDS             22286..23218
                     /locus_tag="VB649_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP1670077.1"
                     /translation="MNINILLSTYNGERFLAEQIQSIQRQTVNDWTLLIRDDGSTDGT
                     QDIIRTFVKEDKRIQWINEGQTENLGVIKNFYTLLKHQKADVYFFSDQDDIWLDNKLE
                     VTLLEAQKHEMTAPLLVYTDLKVVTQHLAICHDSMIKTQSGHANTSLLQELTENTVTG
                     GTMMITHALAEEWTTCDGLLMHDWYLALLASATGKLVYLDIPTELYRQHDANVLGART
                     WSKRMKNWLNPHHLVNKYWWLITSSQKQAQLLLDLPLKPNDHELVTAYVSLLDMPFTK
                     RLATLKRYGFRKNRIFHTFIFRSLVVTLFGYRRK"
     gene            23221..24024
                     /locus_tag="VB649_001120"
     CDS             23221..24024
                     /locus_tag="VB649_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670078.1"
                     /translation="MNFLTKKNRILLREMVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRLGGNVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     IIVFSAVLGALINFLINLVVVLIFALINGVTISGYAYLSLFLFIELVVLVLGIALLLS
                     NVFVYYRDLAQVWEVLLQAGMYATPIIYPITFVLDSHPLAAKLLMLNPVAQMIQDFRY
                     LLIDRANVTIWQMSTNWFYIVIPYLVPFVILFIGIFVFKKNADRFAEII"
     gene            24024..25229
                     /locus_tag="VB649_001121"
     CDS             24024..25229
                     /locus_tag="VB649_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670079.1"
                     /translation="MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQ
                     HVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYC
                     NRAVLIEDGLVKAYGEPFDVANQYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNP
                     RITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQ
                     CQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLY
                     QRNGKWVFH"
     gene            25254..26261
                     /locus_tag="VB649_001122"
     CDS             25254..26261
                     /locus_tag="VB649_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEP1670080.1"
                     /translation="MYKVSIICTNYNKAPWISDALDSFLSQVTDFEVEIIVIDDASTD
                     DSREILKSYQKKSSGKIKLLFNETNIGITKTWIKACLYAKGKYIARCDGDDYWTDSFK
                     LQKQVDVLEASKRSRWCNTDFDFVNSQGDLLYANAFSSGHTPLTDTYEKVLALKGMTM
                     ASTWLVDADLMRQVNQKINVDTPDDTFDIQLELFQLTQLTYIKDSTTVYRMTTDSDSR
                     PTDTPKMIHRIQKLLDTQLNYLKKYNQVDTKEVSKLLLQQDAKQEIRIHELSCFIQEL
                     QQTIVDKTKQQETREVELQNVIEEQKNQLSELRQQYHAIINSRQWKYTSKLIAFIRRK
                     K"
     gene            26258..28003
                     /locus_tag="VB649_001123"
     CDS             26258..28003
                     /locus_tag="VB649_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEP1670081.1"
                     /translation="MNRILLYVHFNKYNKISAHVYYQLEQMRSLFSKIVFISNSKVSH
                     EDLKRLKNHCLIDEFLQRKNKGFDFSAWHDGLITMGFDKLEEFDSLTIMNDTCFGPIW
                     EMAPYFENFEEKETVDFWGITNNRGTKTFKEHVQSYFMTFKNQVIQNKVFQQFWQSII
                     EYENVQEVIQHYETQLTSILLNEGFSYQTVFDTRKAESSFMPHPDFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLNLIRETTNYPIDLIVSHMSQISLPDAKYLLSQKYLNCQ
                     RLAKQTCQKVAVHLHVFYVDLLDEFLTAFEDWNFHYDLFITTDSDIKRKEIKEILQRK
                     GKTADIRVTGNRGRDIYPMLLLKDKLSQYDYIGHFHTKKSKEADFWAGESWRKELIDM
                     LVKPADSILSAFETDDIGIIIADIPSFFRFNKIVNAWNEHLIAQEMMSLWRKMDVKKQ
                     IDFQAMDTFVMSYGTFVWFKYDALKSLFDLELTQNDIPSEPLPQNSILHAIERLLVYI
                     AWGNSYDFRIVKNPYELTPFIDNKLLNLREDEGAHTYVNFNQMGGIKGALKYIIVGPA
                     KAMKYIFLRLMEKLK"
     gene            28000..30474
                     /locus_tag="VB649_001124"
     CDS             28000..30474
                     /locus_tag="VB649_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HEP1670082.1"
                     /translation="MIKDTFLKTNWLNISHHIILLVFGFYFSFYSLAKELVSSTAQPV
                     NYYTHLLNVSFVGYIISLIGLSYYLSRQVSRQLFLKTSFIVISYLIVSYWVQITQHLN
                     DKRFDIWSLTKNQFYQFQALPYLLIILVMATLIKILVAYFAIEKDRFGLLGYQGNTFS
                     VALILAVVPINDIHLLKLISSRFSELVTAGNSQIALLKISGLLIVLLVIFATIIYVVL
                     NALKHLKSNKPSFSVAATTSLFLALVFNYTFQYGVKGDEALLGYYVFPGATLFQIVAI
                     TLVALLAYVITNRYWPTTFFLLILGTIISVVNDLKESMRSEPLLVTDFVWLQELGLVT
                     SFVKKSVIVEMVVGLAICIVVAWYLHGRVLAGKLFMSPVKRASAVLGLFIVSCSMLIP
                     FSYEKEGKILSGLPIISALNNDNDINWLGFSTNARYKSLAYVWTRQVTKKIMEKPTNY
                     SQETIASIAQKYQKLAEDINKDRKNNIADQTVIYLLSESLSDPDRVSNVTVSHDVLPN
                     IKAIKNSTTAGLMQSDSYGGGTANMEFQTLTSLPFYNFSSSVSVLYSEVFPKMAKPHT
                     ISEFYQGKNRIAMHPASANNFNRKTVYSNLGFSKFLALSGSKDKFKNIENVGLLTSDK
                     TVYNNILSLINPSESQFFSVITMQNHIPWSSDYPEEIVAEGKNFTEEENHNLTSYARL
                     LSFTDKETRAFLEKLTQINKPITVVFYGDHLPGLYPDSAFNKHIENKYLTDYFIWSNG
                     TNEKKNHPLINSSDFTAALFEHTDSKVSPYYALLTEVLNKASVDKSPDSPEVKAIQND
                     LKNIQYDVTIGKGYLLKHKTFFKISR"
     gene            30653..31348
                     /locus_tag="VB649_001125"
     CDS             30653..31348
                     /locus_tag="VB649_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEP1670083.1"
                     /translation="MKKLIIIPAYNESSNIVNTIRTIESDAPDFDYIIIDDCSTDNTL
                     AICQKQGFNVISLPINLGIGGAVQTGYRYAQRCGYDVAVQVDGDGQHNPCYLEKMVEV
                     LVQSSVNMVIGSRFITKEGFQSSFARRIGIKYFTWLIALLTGKKITDATSGLRLIDRS
                     LIERFANHYPDDYPEPETVVDVLVSHFKVKEIPVVMNERQGGVSSISLTKSVYYMIKV
                     TLAILVVRLKGNR"
     gene            31350..31691
                     /locus_tag="VB649_001126"
     CDS             31350..31691
                     /locus_tag="VB649_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEP1670084.1"
                     /translation="MTVTASLFISFIVLTFVFFLINLIKKDKLAIKYSLLWFILALLI
                     LLFTWLPNILNKMSHFLGIHSPTNMLFFLGFCLSLAIIFSLTNNISLQNDKVKRLTQE
                     VALMKKEKTND"
     gene            31684..>32217
                     /locus_tag="VB649_001127"
     CDS             31684..>32217
                     /locus_tag="VB649_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEP1670085.1"
                     /translation="MINPSKQNQTIFLWNMLGSLSTAVISVILLMVVTRLLTSADSDI
                     YAFAYSFANMMVVVGLFQVRNYQATDINEKYSFSQYLVARLMTCLLMLAITVIYLTLT
                     KTDSYKSTIVFLVCFYRSTDAFSDLYQGMFQQHERLDIAGKSLAYRNTLIFMVYTAII
                     LYSKNLTLALVAVCIVSL"
BASE COUNT        10481 a         5419 c         6333 g         9984 t
ORIGIN      
        1 aaagtcactg atttaagatt gtcactaagc actttttttg atagaataga actaattgaa
       61 taagtgtcta tgagactagt actaatagag aaattaacag ggagtgaggg ccgtgactgg
      121 aagccttctt aagggaacta ttaggaattc actcagctaa agacaattaa ttaaggtctg
      181 ataacatcag ataaaaacgg atggtaccgc gtgtcaacgc tccgcttatc aagtggagga
      241 gtggcatgct tttttcatcg ccaaaagaag ggaaaactat ggatttacaa gcacaattag
      301 aggaattaaa gacaaaaaca ttggagacct tacagtcttt gacgggtaat cataccaaag
      361 aactgcaaga tttgcgcgtg gctgttcttg ggaaaaaggg atctttgaca gaattactaa
      421 aggggctaaa agacttgtct aatgacttgc gtcctgtggt tggtaaacag gtgaacgaag
      481 ttcgtgactt attgacaaaa gcctttgaag aacaggctaa aattgtagaa gctgctaaaa
      541 ttcaggccca acttgatgct gaaagcattg atgtgacttt accgggtcgt caaatgactc
      601 tgggccaccg tcatgtgtta acacaaacca gtgaagaaat cgaagatatt ttcttaggaa
      661 tgggttttca gattgttgat ggctttgagg tagaaaaaga ttattacaac tttgagcgca
      721 tgaatttgcc aaaggatcac cctgcccgtg acatgcaaga tacgttttat atcacagaag
      781 aaatcttgtt acgaactcac accagtcctg tgcaggcccg tactcttgat caacatgatt
      841 tttcaaaagg gcctttaaaa atggtttctc caggtcgtgt tttccgtcga gacaccgatg
      901 atgctaccca ctcacatcaa ttccatcaaa ttgaaggttt ggtcgtgggc aaaaatattt
      961 ccatgggaga cctcaaaggg actcttgaaa tgatcatcaa gaagatgttc ggtgaagaac
     1021 gtagcattcg tttgcgcccg tcatatttcc cgttcacaga accatctgtt gaagtggatg
     1081 tttcttgctt taaatgtggt gggaaaggct gtaatgtctg caagaaaaca ggatggattg
     1141 aaattcttgg tgctggtatg gttcacccaa gtgtcttgga aatgtcaggt gttgatgcaa
     1201 aagagtattc aggctttgcc tttggtttag gtcaagagcg aattgccatg ttgcgttatg
     1261 gcattaatga cattcgtggt ttctatcaag gcgaccaacg tttctctgaa caatttaact
     1321 aaaacgagtc gtttgaagac ctctgtcagc tattttatct aagattgagt gaaagttgat
     1381 aggtaatgat aataggttaa ttgtctaagg ggaaagtccc tctcgtttca acgtcataag
     1441 ggttttgact tggaacttaa aatacgaaag gaaatgactc aaatcacggc ttgagagcct
     1501 tctctagccg agtgatttgg gcactaaaat tatgttagta tcttataaat ggttaaaaga
     1561 attagtagat atcgatgtga cgccagcagc acttgctgag aaaatgtcga caacgggtat
     1621 cgaggtagaa ggaattgaag tccctgcaga aggtttatca aaactggttg tggggcatgt
     1681 gctttcttgc gaagatgtgc cagagacaca tttgcatttg tgtcaggtag atacaggtga
     1741 tgaaacgcca cgtcaaattg tgtgtggcgc accaaatgtg aaagcaggga ttaaggttat
     1801 cgtggctgtg ccaggtgctc gtattgcgga taactataaa atcaaaaaag gcaaaatccg
     1861 cggcatggaa tctcttggta tgatttgttc cttgcaagaa cttggtttgt cagatagtat
     1921 cattccaaaa gaattttcag acggtattca aatcttgcca gaagaggctg tgccaggtga
     1981 tgccattttt aaataccttg acttggatga tcatattatt gaattgtcca ttacacctaa
     2041 ccgtgcagat gcgctttcta tgcgaggtgt ggcacatgaa gtcgcagcta tttatggcaa
     2101 gtcagtatca ttcccccaaa aaaatctaca agaatctgat aaggcaactt cagaagccat
     2161 tgaagtggcc attgcctctg ataacgttct aacttacgct agccgtgtcg ttgaaaatgt
     2221 caaagttaag ccgagtccac aatggttgca aaacctttta atgaatgctg gtattcgtcc
     2281 tattaataat gtggttgatg tgaccaacta tgtgctcttg tactttggtc aacctatgca
     2341 tgcttttgat tatgataaat ttgaagacca taagattgtg gcgcgtgtgg ctcgtcaagg
     2401 ggaaagttta gtcacacttg atggtgaaaa acgggatttg accactgagg atcttgttat
     2461 taccgtggct gacaaaccag ttgctttggc aggtgttatg ggtggtcaag ccactgaaat
     2521 tgatgccaac tctcagacgg ttgttcttga agttgctgtt tttgatggca aatcgattcg
     2581 taaaaccagt ggtcgtttaa accttcgttc ggaatcatct tcacgctttg aaaaaggtgt
     2641 taactatgca actgttttag aagcacttga ctttgcagcg gctatgttac aagaattagc
     2701 agaaggtcaa gtcttatcag gccatgttca agctggtcaa ttgtcaacag aacctgttga
     2761 agtctcaact aaccttgact atgtgaatgt tcgtttagga acagagttaa cttttgaaga
     2821 cattcaaact gtttttgatc aacttggttt tggactgaca ggagatgaaa caagcttcac
     2881 ggtagctgtt ccgcgccgtc gttgggatgt tagcatccca gctgacttgg tggaagaaat
     2941 tgcgcgtatc tatggttatg ataagttgcc gacaacctta ccagaggcag ggggaacggc
     3001 tgcagaatta acgccaacac aggctcttcg tcgtaaagtc cgtggcttag cggaaggact
     3061 gggcttgact gaaatcattt cgtatgcctt gacaacacca gagaaagctg ttgagtttgc
     3121 agtggcacca agtcacctaa cagaactcat gtggccaatg tctgtggaac gttcagcgct
     3181 tcgtcaaaat atggtttcag ggatgttaga tacggtagct tataatgtgg ctcgtaaaca
     3241 aagtaacttg gctctttatg aaattggaaa aatctttgaa caagaagcta atccaaaaga
     3301 agaccttcct aatgaagtga accattttgc ttttgctatt tgtggcttag tggcacaaaa
     3361 agatttccaa acccaagcac aggtagtgga tttttaccat gctaaaggta tcttggatac
     3421 tttatttgca aaccttaacc tcaaggttca atatgtgcca accaaagacc tagcaaacat
     3481 gcacccagga cggacagcgc ttatcctatt agatgagcaa gtgattggat ttgttggtca
     3541 agttcatcca ggaacagcaa aggcttatag tattccagaa acctatgtgg cagaattgga
     3601 tatggctgct ttagaagcag cgttgccaag tgatcaaact tttgcggaaa tcacaaaatt
     3661 ccctgctatg acacgtgatg ttgccttgtt acttgaccgt gaggtgagtc atcaggccat
     3721 tgtaacagct attgaatcag caggtgtaaa acgcttgact agcattaaac tctttgacgt
     3781 ctatgaagga gcaaccattc aggctggcaa aaaatcaatg gcttatagcc ttactttcca
     3841 aaatccaaat gacaatttaa cggatgaaga agttgccaaa tacatggaga aaatcaccaa
     3901 agcattgaca gaacaagtcg gtgctgaagt acgctaagaa aaaaactggg cctctaaggc
     3961 tccgtttttt tctgttataa tagaggaaaa aagaactcca gttcaaatga ttggagaaaa
     4021 acatcagaag gtggaggaaa atcagaatgt atcaaacaaa aataacaggc aaccgccttt
     4081 accacacggt ttcgaaaggc tacggagata gtgtaacctt atttggaaaa actgatcaag
     4141 gggaaacccc tatgagttta ctggttattg ccttgtcttc ttgtgtgact atgtgtgtgc
     4201 agggttttta ccatcgtcaa tttcagcaag acacacttgc tgtttctgtt gaggctagtt
     4261 atgaggaaga agtttttgaa ctacttgtta ggattgatga tgttttagat gacaaaaaga
     4321 aagctgattt attggcttac attggaactt attgtcgtgt gaaacaactc ctcaaacctg
     4381 aagttacggt gaccattacg ttggaaggac tgtctcatgt ctgatgctag tttgaaaact
     4441 taccaaaaac aatgggctta tcaaaagtat tgggtcatgg cacactcaca gcagcattac
     4501 aatgctttaa gagaattgtt taaaggaaat cagtggtcag aagaaaaggt gttgactttt
     4561 cattgtttga ttgaagaagc gcaagccatt cctcccacag taaaaagctt acgaacagta
     4621 tatcagcatg tttgggggta ttttaaaaag gtagcgagtc aggaagaaaa agaccatttc
     4681 aaagatttgg atgctcagtt ggaaactaaa tctgaggaga tgctatgctt tttacaagag
     4741 atgactgctc attatcagcc ctcttatctg ctatcttgcc gtttgattac caaaggtcct
     4801 taaatgctaa acagaaaagt agggatttct gggaagttat gctaagctag tgatataaat
     4861 aagggggaat gagagatgtt tttagcgctt aatgaaatga aacaatccaa attgcggtat
     4921 ggtttgattg ctggtttgct atgtttggtt gcctatttga tgttcttttt gtcaggattg
     4981 gcctttggtt tgatgcagga gaaccgctcg gcggttgatc tttggaaagc tgacagtgtt
     5041 ttactagcca aggatgctga tgctaccttg accttatcac aggtatccag agctcaagaa
     5101 aatcaaataa cagcagacaa ggtagctcct cttgctcaac tcaataccgt ggcatggtca
     5161 gttaaaaatc ctaaggatgc cgacaaagtt aaggttagcc ttttcgggat tgattctact
     5221 agctttattc gtcctaacat tgtaaaaggt cgattattta agactaacaa agaggttgtt
     5281 ttggatcaaa gccttgcaaa agaggaagct tttgcgattg gcaaggactt ttacacatcg
     5341 agttctagtc aagcattaac tatcgttggc tatactcaaa atactagatt tagtgttgca
     5401 ccagtggttt atatgaattt ggaagctttt gaaacattaa aatatggaga accactacca
     5461 aaagataagc aagttgttaa tgcttttatc actaaaggaa gtttaacaga ttatcctaaa
     5521 aaagacttcc aaaaattaga tattaaaacc tttattacta aattacctgg ttatagcgct
     5581 caacttttaa cttttggctt tatgattagt tttcttgtca ttatttcagc tattattatt
     5641 ggtattttta tgtatatttt gactattcaa aaggcaccta tttttgggat tatgaaagcg
     5701 caaggtatcg ggaatataac gattgcacaa gcagttctgc tgcaaacctt tttgttaagt
     5761 gctttaggaa gcggtttagg gttattggga acttggttga cgtctttagt gctccctgaa
     5821 gcagttccct tccaaagtaa ttggctagtt tacttagcga tattagtcag tatggtttgt
     5881 tttgctttgt taggaacctt attttctgtt tttagcattg tacgaattga tcctttgaaa
     5941 gcaattggat aggaggtagt gatgtcggtt ttaacattta aacaagtgac caaaacattt
     6001 caagatggtc atcacgaaat caacgcatta aaggcaactg acttttccat tgaagctgga
     6061 gaatttgtgg ctattattgg accatcaggt tctggaaaat caaccttttt gaccattgct
     6121 ggtggcttac agaccccaag ctctggtcag ctaatcattg atggcactga ttatacccat
     6181 ttatcagaaa aagagcgctc acgcttgcgc ttcaaatccg ttggttttat cttacaagct
     6241 tccaatctga tacctttttt aacggtccag cagcagttgg aattggtcga tcatttgaca
     6301 ggaagcaaag aaaaagccaa agccaatcag ttatttgacg atttaggcat tgcagggcta
     6361 aaacatcagt tacctcaaga attgtccggc ggagaaaggc aaagagcggc tattgcccgt
     6421 gctctttacc atgatccagc actgatattg gcagacgaac ctactgcaag tttggatact
     6481 gaaaaagcct atgaagtggt caaactgttg gctaaggaaa gtaaagaaaa aaacaaggcc
     6541 attattatgg tcactcatga tgatcggatg ctggcatctt gtgacaaggt ttatcacatg
     6601 gaagatggtg tattgcgtcg agaaaaatag gccgagttgt tattgctgtt tgaaagaaaa
     6661 ataaaaacca aacaagtgct acacttgttt ggtttttatt tgcgtaatgt tggtttttct
     6721 tagttaaagt ttattgtaag ggacgctgaa ggtgtcgcca tgctcaaagt caccatattg
     6781 gtaacctcgg tcaaaccaac gctgtcgttg ttgcgaagtt ccgtgggtaa aactatctgg
     6841 aacggctctg ccataagctt cttcttgcag agtatcatcc ccaactgcgt gagctgctgc
     6901 cattgcctcc tcaatatctc ctttttctaa aaggccttgc ccttgaacat aattagccca
     6961 agcaccagca tagtagtcag cctgaagctc taacttaaca ttgagttgat tggcttctgc
     7021 ctttgagcgt ccttgtctag cactagcgta gtcttccatg gtgccaattt cattttggat
     7081 atgatggcca acttcatgag caatcacata ggccatggca aagtcacctt tggcgccgta
     7141 tttagtagac aactcatcgt aaaacgaaat gtctaaataa actttttggt cgcctggaca
     7201 atagaaagga ccagcagagg cttgacctgt cccacaagat gtctgtgtgg caccagaata
     7261 taagactaag gttggtttgt tgtaagttaa ccccttatct ttaaactgtt tggtccaata
     7321 gtcttcggta gaggcgaaga ccttactgac aaaagaaacc tgctcttgac tagccttatc
     7381 accatttgta cgtgttactt ggcttgattg gtaggcattg ttattggagg aagaaggatt
     7441 gcctcctaaa acaccagata ggccaccccc tcccatgact aggagaagga gtagaataac
     7501 cagtttggtt ttccaacctc ctcgtgaaaa gagtaattga agtagaagac cgccccctag
     7561 gccgccgccc ccaaaagaac cagacgattg accacgtcta tcttcaacct gttgactttc
     7621 tctcaaatca tccgttttca taagtttctc ccatctattt cttgatttta ttataaaata
     7681 attctattag aattgctatt tttatgatga gattataact aaaaatagga aaagcaatag
     7741 gtatttgcta taatataaca agggtagatt cagtttgtat aaaggagtca tatgaaatta
     7801 atttacacag agatgagtta ctcgatgaca gagattttgg tgaatgaagc acgaaaagct
     7861 gctgaccaag gttatcgagt gttctatatt gctccaaatt ctctttcatt tgaaaaggaa
     7921 agagaagtct taaccttatt gcctgaacga gggacttttt cgataatagt cacccggttc
     7981 gttcaaatgt caaggtattt tacagttgag agctctcctt ctaagcaaca tctagatgac
     8041 acgactttgg ctatgatttt ttatcgggcc ttgatgcaat taaaaccaga agatttgcca
     8101 agttatggtc gtttgcaaaa taattcggtt tttattgaac aactagttga gttatataag
     8161 gaattaaaaa acgcacaatt aagcgtacat gatttaacag ggttagacca tcctcaaaaa
     8221 caagaagatc ttattaaaat tattgagctt gcagagacga tcatgattca gcaagattac
     8281 aatcaagata gtcctctaca atcttttgca agagcaatta agttaggact tttaaataat
     8341 caactatcaa aaacagttat tgttattgat ggtttttcac gtttttcagc tgaagaggat
     8401 tatttattat cacttttaaa taacaactgt caagaggtca tcattggcag ttatgtgagt
     8461 caaaaagctt atcaaaaatc ttttattaag ggaaatatct atgaggctag ccttcatttt
     8521 ttgcaagatt tggctcaaaa ataccatatc aagccgatat ttgcgacctc taatcaagtg
     8581 tttaaaccag ccttttcacg gctaacacaa ttatttgaag caactcatga tttttcacaa
     8641 gtagactggc aactccaaaa gaatgatctt gatcacttta gcctttggca atgtcatcat
     8701 caaaaagagg aaattgaaca tgtagcaaaa tccattcggc aaaagctata tgaaggttac
     8761 cgttataagg atatcttagt gttgctagga gatatggatg cttatcaatt acaaattggg
     8821 cctatctttg ataagtttga aatcccctac tatttaggaa aagcagagcc tatggctgcc
     8881 catccattag tccaatttat agaatcgctc gaacgaagtc agcgctataa ttggcgtcgt
     8941 gaagacattt taaacatgtt aaaatcagga ctttttggtt gttttgatga tagtgatatt
     9001 gatcgctttg aggaatatac tcagtttgca gatattaaag gatttactaa attttcaaag
     9061 ccttttacca ttaactcttc taggcagtat cctcttgact ttttaaatga aatgagacaa
     9121 gacatcgttt tacctttgca agaattgttt aagagtcaaa aacaacttgg tgcttcactt
     9181 gttgacaaat taatactttt tttaaaaaag attagattag ctgagaatat gcaaggttta
     9241 gcacagtccc aattagaggt ggaaaaaaac gaagaagttt ggaaaaggtt tacagatatt
     9301 ttgacttctt ttcatcatat ctttggccaa gaaaaattac ggctatcaga ttgccttgct
     9361 ttaatcaaaa cgggaatgaa atcagctcag tatcgtgttg ttccagcgac attagatgtt
     9421 gtcaccatta aatcttatga ccttgttcaa ccacattcaa aacctttcgt ttatgcaatt
     9481 ggtctaactc aatcacattt tcctaagcaa attcaccatt caggactact ttctgatcaa
     9541 gagcgtgcta gaattaatga aataagaaat tatcgtcatt ttgatattgc tagtgccgaa
     9601 aatagtaaaa aaaaccatca aactgcgtta tctctgttta atgctgctac taaggagtta
     9661 gttcttagtg tttcaacggt aatcaacgag acattcgatg atctatctcc ttatcttaaa
     9721 gaattaataa actttgggtt acctcttttg gataaaggca aaaactatct atcttatgat
     9781 aatagcgata ttggtaacta taaagctctc ttgtcacaaa ttattgctat taaccgacaa
     9841 gatcttatag aaatgtcaga tcaagataag atgttttgga ctgttgtctt acgttatctc
     9901 aggaaacagt taagaaagca acagctagag ctacctactt tagattatcg tttatcaaca
     9961 aagcctttgt ctaaagaagt tatcgaggta tgttttccaa agggaatctc tttaaagcta
    10021 tctgcaactg ctttaaccgt tttttataat aatcagtaca actatttttt gaaatatgtt
    10081 ttgaatttaa acaaaacaga atccattcat ccagattcca gaattcatgg tcaatacttg
    10141 catcgtgtct ttgagcggtt aatgaaagat cacacgcaag aaccgtttga taataagtta
    10201 aaacaagcaa tttaccatac caatcaagaa agtttttttc agcaggttta ccaagataat
    10261 gccgaggctg agtacagttt agctatacta gaagatattg ttagatcaac agcacctatc
    10321 ttgcaactta accaaaacat acaggtcatt gatcaagaaa agaactttca gctggatatg
    10381 ggaaatgaga tattagtcca cgggatcatt gatcgtattg accagctgag cgacggtagc
    10441 ttgggcattg ttgactataa atcaagcgcg aatcaatttg atattgggac cttttataat
    10501 gggttgagtc cacaactagt gacttacctc gcagccttaa aacagattgc accgcacgat
    10561 ataaaccaat tatttggggc tatgtacctt catttgcaag atcctaaatt ggatctagta
    10621 acatttaaac aaattgataa cacattagtg gagagtatct ataaagcgtt gacctataaa
    10681 ggtatttttt cagaagtcga aaaagagcat ctatctactg gtgcttacca aaccaaaaat
    10741 gctctttatt ccaatgacga attggaaaca cttttaaatt ataacaagta cctctatctt
    10801 aaagctgcta aacacattaa aaagggacat tttttgatta atccttatac aagcgatggt
    10861 aagacagttc aaggagatca attaaaagcc attacccgtt ttgaagcaga tcttgacatg
    10921 ggacaggcaa ggcgactagt gactctccct gctaaggaga aaaaagagtg ctttttaaca
    10981 ttaatgagaa aggagggcca cttgtgattt cttttgcccc atttttaagc cccgaagcta
    11041 ttaaacattt acaagaaaac gaaaggtaca gtgatcagtc tcaaaaacgc acagctcaac
    11101 aaattgaagc aatttatact agtggccaaa atatacttgt atcagcttct gctggttcag
    11161 gaaaaacctt tgtaatggtc gaacgcatac ttgataaaat tttgagaggt gtttcaattg
    11221 atcggctttt tatctcaacc tttactgtta aagcagctac agaactgcgt gaacggattg
    11281 aaaacaaatt atactcacaa attgctcaaa ctacagattt tcaaatgaaa gtttatttaa
    11341 cagaacaatt gcaatctctt tgtcaagctg atattggtac tatggatgct tttgcacaga
    11401 aagtagtaag tcgctatggt tatagcattg gcatttcatc ccaatttcgt atcatgcagg
    11461 ataaagcaga acaagatgtt ttaaagcaag aggtgtttag caaactcttt agtgagttta
    11521 tgaatcaaaa agaggcaccg gcgtttaggg ctcttgtgaa aaatttttct ggtaactgta
    11581 aagacacttc agcttttaga gagttagttt atacttgtta ttcttttagc caatcgacag
    11641 aaaatccaaa aatatggttg caagaaaatt ttctaagcgc tgctaaaact taccaaagac
    11701 ttgaagatat cccggatcat gatattgaac tcttactttt ggcaatgcaa gacactgcaa
    11761 atcagctaag agatgcgact gatatggaag attatgggca gctgactaag gcaggtagcc
    11821 gatctgctaa atacactaaa cacttaacga tcatagaaaa gttgtctgat tgggtgcgtg
    11881 attttaaatg tttgtatgga aaagccggat tggatcggtt gatcagagat gtgacagacc
    11941 ttataccatc tgggaatgat gttacagtct cgaaggtaaa ataccctgtt tttaagacct
    12001 tgcatcaaaa attaaaacaa tttaggcatt tagaaacaat tttaatgtat cagaaagact
    12061 gttttccctt attggaacag ttacaagatt ttgtgcttgc gttttcagaa gcttatttag
    12121 ctgtcaaaat acaagaaagc gcttttgaat tttcagatat tgcacacttt gcaatcaaaa
    12181 ttttagagga aaatacggat attcgccaat cctatcagca acactatcat gaggtgatgg
    12241 ttgatgaata tcaagataac aatcatatgc aagagcgact cctgacctta ctatcgaacg
    12301 gtcataatcg ctttatggta ggagatatca aacaatcgat ctatcgattt cggcaagccg
    12361 atcctcagat ttttaatcaa aagtttagag actatcaaaa aaaacctgag caggggaaag
    12421 tgattttact caaagaaaac tttcgtagcc aatcagaggt gttaaatgtc agcaacgctg
    12481 tttttagtca cttaatggac gaatcagtag gagacgtctt atatgatgag caacatcagt
    12541 taatagcagg tagttatgct caaacagtcc cctatctaga ccgtcgtgct cagttattgc
    12601 tatataatag cgataaagat gatggcaacg ccccttcaga tagtgagggt atttcattta
    12661 gtgaggttac aattgttgcc aaagaaatta ttaagcttca caatgataag ggtgtccctt
    12721 ttgaagacat tacgttactc gtttcttcaa gaacaagaaa tgatatcatt tctcatacat
    12781 tcaatcaata tggtattcct atagtaacag atggtgggca gcaaaactat cttaaatctg
    12841 ttgaagtgat ggttatgtta gatacattac gcaccattaa taacccaaga aatgattatg
    12901 cccttgtggc tttactgcgc tcaccgatgt ttgcctttga tgaggatgat ttagcaagaa
    12961 tagcacttca aaaagacaat gagctagata aagattgcct atatgacaag atacaaaggg
    13021 ctgtgattgg aagaggtgct catcctgaat tgattcacga taccttgctt ggcaagttaa
    13081 atattttttt aaagacgttg aaaagttggc gtcgatacgc taagctaggg tcgttgtatg
    13141 acttgatttg gaaaattttt aatgatcgtt tttattttga ttttgtagct agtcaagcaa
    13201 aagcagaaca agcacaagct aatctatacg cattagctct acgtgctaat cagtttgaaa
    13261 aatcgggcta taaagggcta taccgtttta ttaaaatgat tgataaggta cttgagacgc
    13321 aaaatgactt agcagatgtg gaagtggctg ctcctaaaca agctgttaat ttaatgacca
    13381 ttcacaagtc taaaggttta caatttccgt atgtatttat ccttaattgt gacaagcgct
    13441 tctcaatgac agatattcat aaatcattta ttctgaatcg gcagcacggt atcggtatca
    13501 agtaccttgc agatatcaaa ggtttacttg gtgaaacaac actcaattct gttaaagtaa
    13561 gcatggaaac cttaccttat caattgaaca aacaagagtt gcgcttagca actttatcag
    13621 aacaaatgcg cttattgtat gttgctatga cacgagctga aaaaaaagtt tattttattg
    13681 gtaaagctag taagagcaaa agtcaagata tcacagatcc taaaaagtta ggcaaacttt
    13741 tgccgctggc tttacgagaa cagttattga cattccaaga ttggctatta gcaatagcag
    13801 atatattttc aactgaagat ctttattttg atgttcgctt tattgaagat agtgatttga
    13861 cacaagagtc agtcggacga cttcaaacac cacagttatt aaatccagat gatcttaaag
    13921 ataatcgtca atcagaaaca attgcacggg ctttagatat gttagaagca gtgtctcaat
    13981 tgaatgccaa ttatgaagca gctattcatt tgccaacagt tcgaacgcct agccaactta
    14041 aggcagctta cgagccttta ttagaaccca ttggtgtaga tattatagag aaatcttctc
    14101 gatcgctatc tgattttact ttgccacatt tttcaaaaaa agtaaaagtt gaagcaagtc
    14161 atattggatc agctcttcat cagttgatgc aggtgctccc tttgtcaaaa ccgataaatc
    14221 aacaaacgct tttagacgct ttaagagaaa ttgatagtaa cgaagaggta aaaacagctc
    14281 ttgatctcaa aaaaatagag tcgttctttt gtgatacaag cctaggccaa ttttttcaga
    14341 cttaccaaaa acacttgtat cgagaagcgc catttgctat tttaaaactt gaccctatta
    14401 gtcaagaaga atatgtccta cgtggtatta tagatgccta ctttttgttt gatgatcata
    14461 ttgtattagt ggactataaa acagataaat acaagcagcc cattgagtta aaaaagcgtt
    14521 accaacaaca gttggagtta tatgcagaag ctctcactca aacgtataaa cttcctgtga
    14581 ctaagcgcta tcttgtttta atgggaggtg gaaagccaga aattgtcgaa gtttaaggtt
    14641 gttgtgacac aagggtattt tgcaaatgat aatagtatag ttgaggattt tacgaaatgc
    14701 ttgaaaagct attgaccttt gaataataat acaatataat aagttttatt agcgacaaaa
    14761 aggaataaat atactatgaa ttttaaaaaa ataagatttg gttttttgct ttgcctccta
    14821 ctttatcctt tagcagcttg taacaagtct gaacaactta atcactacga aagaattaaa
    14881 aaaacaagaa aattagtcgt tgctgtaagc cctgattatg ctccttttga atttaaagct
    14941 ttagttaatg gaaaagatac tattgttgga gcagatgttc aattagctca ggctattgct
    15001 gatgaattag acgttgatct tgagctttca ccaatgagtt ttgataatgt tttgtctagt
    15061 ttacagactg gtaaagctga tcttgctatt tcaggaatct cacatactaa agaaagagct
    15121 aaagtatatg atttttcaat tccttactat caggcagaaa acgctatagt gatgagagca
    15181 tctgatgcta aagtgaccaa aaatattagt gacctaaacg gtaagaaagt agccgctcaa
    15241 aaaggtagta tcgaggaagg tttagttaaa atacaattac caaaggccaa tctgatttct
    15301 ttggctgcta tgggagaagc cattaatgaa ctaaaagcag gacaagtcta tgcagttacc
    15361 ttagaaacac ctgtagctgc tggtttttta gcccaacata aggatctggc tttagcaccc
    15421 tttagcttaa aaaccagtga tggagatgcc aaagcagtgg cccttcctaa aaatagtggt
    15481 gacttaacca aagccgttaa taaggttatt gctaagttag atgagcaaga acggtacaag
    15541 tcatttattg cagagacaat agcactaacg aaaaatacta tgaagtaata aggttaataa
    15601 aaactttatt agtatccgtt ggaaaagtgt ttggaataaa caataaaaga ggtttgactt
    15661 ttttaaaaaa ataatgtaat ataattggga acgtgaaaat gttacaatat cttgaggagg
    15721 tgaaacacat gtcaaaaaca gtagtacgta agaatgaatc tcttgacgat gctcttcgtc
    15781 gcttcaaacg ttctgttact aaagctggta ctcttcaaga atcacgtaaa cgtgaattct
    15841 acgaaaaacc ttctgtaaaa cgtaaacgta aatcagaagc agctcgcaaa cgtaaaaaat
    15901 tctaatagta aaaaataaaa acagttctaa ttgtgagaac tgtttttatt ttttattcag
    15961 aagaagcaag ggagcttttt tgatatcaaa aaaagcagtt agacatgcct aactacttta
    16021 tcaaaaatcg ctttattttt gagccaacaa atcacggatt tctgtcaata attcttcttg
    16081 agtaggagct gcagcttctt tttccttttt aggcatagct ttttcagcgg cttttacaac
    16141 aaagaaaaga ctggtaccga tgataagaaa attaataacg gctcctaaaa agctaccata
    16201 tttaacacca ttccatgaca attgagtgat gttttcaaca tttgcagctt tcagagctgg
    16261 gtttaaaata agcggtgtga taatatcgtt cacaaaagaa gtgacaatag caccaaaagc
    16321 tcccccgatg ataactgcta cagcaagttc aataatgttt cctctaaaca aaaatgcttt
    16381 taattcttta accattaaat attccccctt ttaatatctc taagttaagc atagcataat
    16441 tagtaaacaa aatccaatgg aatcacttca gtttttaaat ttacaaaaaa gagtttcggt
    16501 ggtataataa aacgtaaaac taaaatggga tttttatggg gaggtgacga tttggcaatt
    16561 gacaaagaaa cgatttccca agtaaaaaat agcgttaata ttgtcgatgt cattggagaa
    16621 gtggtcaaac tttcccgatc agggcggcat tatctcgggc tttgcccatt tcataaggaa
    16681 aagacaccct cttttaatgt tgttgaagac agacaatttt ttcactgctt tggctgtgga
    16741 aaatcagggg atgtttttaa atttattgag gaataccgcc aagtcccctt cttagaaagt
    16801 gttcagatta ttgccgataa gactggtatg tcgcttaata tatcgccaag tcaggcagta
    16861 attgctagcc aacacaagca ccctaatcac gctttgatga cacttcatga ggatgctgct
    16921 aaattttacc atgcagtttt gatgaccact accattggtc aagaagctag gaagtacctt
    16981 taccagagag gcttggatga ccaattaatt gagcatttca atattggttt agccccagat
    17041 gagtcagatt atctttatca agctctttct aaaaaataca aggaaggtca attggttgct
    17101 tcaggattgt ttaacttgtc cgatcaatcc aataccattt acgacgcctt tcgaaatcgt
    17161 atcatgtttc ccttatcaga tgaccgaggg catattattg ccttttcagg acgtatctgg
    17221 acggcagctg atatggaaaa gagacaggcc aagtataaaa attcaagagg aacagttctt
    17281 tttaacaaat cttatgaatt gtatcatctg gacaaggcaa ggcctgttat tgccaaaacc
    17341 catgaagtgt ttctaatgga agggtttatg gacgtgattg ccgcttaccg ttccggctat
    17401 gaaaatgctg ttgcttcaat ggggacggca ttgactcaag aacatgtcaa tcaccttaag
    17461 caagtcacta aaaaagttgt tttgatttat gatggtgacg atgctggaca acatgctatt
    17521 gcaaaatcac tagaattgct taaagatttt gttgtcgaaa ttgtcagaat ccccaataaa
    17581 atggatcctg acgaatttgt acaacggcat tccccagaag catttgcaga tttgcttaag
    17641 cagtcacgga tcagtagtgt tgaatttttt attgattacc taaaacctac taatgtagac
    17701 aatttgcaat cacaaattgt ttatgtggag aaaatggcac cattgattgc tcaatcacca
    17761 tccatcacag ctcaacattc gtatattaac aagattgctg atttgttgcc aaactttgac
    17821 tattttcaag tagaacaatc agtaaatgca ttaaggattc aagataggca aaagcgtcaa
    17881 ggtcaaatag ctcaagccgt cagcaatctt gtgaccttac caataccaaa aagtttgaca
    17941 gctattgcta agacagaaag tcatctcatg catcggctct tacatcatga ctatttatta
    18001 aatgaatttc gacatcgtga tgatttttat tttgatacct ctaccttaga aatactttat
    18061 caacggctga agcaacaagg atacattaca tcttatgatt tgtcagagat gtcagaggaa
    18121 gttaaccgtg cttattacaa tgttttagaa gaaaaccttc ccaaagaagt agctcttggt
    18181 gagattgatg atattttatc caaacgtgcc aaacttttag cagagcgcga tcttcacaaa
    18241 caagggaaaa aagttagaga atctagtaac aaaggcgatc atcaagcggc tctagaagta
    18301 ctagaacatt ttattgcgca gaaacgaaaa atggaataga ggaaattatg acaaaacaaa
    18361 aagaaataac aacttttaac gttcaagttg cggagtttat tcgccatcac aaaaaagaag
    18421 gaacagcgat tgatgatgac gtgaccgaaa aacttgtcat tccatttgct ttggatgctg
    18481 atcagattga tgatttactt gagcggttaa cagatggtgg tatctcgatt acggataaag
    18541 aaggtaaccc atcatcaaaa tacattgttg aagaaccaaa accagaagaa ttaactgatg
    18601 aagaattaat tggtagtaat tcagctaaag taaacgaccc tgtccgcatg tacctcaaag
    18661 aaattggtgt ggtaccgctt ttaacaagtg aagaggaaaa agaattggct gttgcagttg
    18721 ccaagggaga tttaatggct aaacaacgtt tagcggaagc aaaccttcgt cttgttgtct
    18781 caattgcaaa acgttatgtt ggacgtggaa tgcaatttct tgatttaatt caagaaggta
    18841 acatgggact catgaaagct gttgataaat ttgattattc aaaaggattc aaattctcaa
    18901 cttatgcaac atggtggatt cgtcaagcta taacacgcgc aattgcagat caagcacgta
    18961 cgattcgtat ccctgttcat atggttgaaa cgattaacaa attagtccgt gaacaacgta
    19021 accttcttca agaacttggt caagatccaa cgccagaaca aatcgcagaa cgtatggaaa
    19081 tgactccaga caaggttcgt gaaattctaa aaattgctca agaacctgtt tctttagaaa
    19141 caccaattgg ggaagaagat gatagtcact taggtgattt tatcgaagat gaagttattg
    19201 aaaatccagt agattatacg acgcgtgttg ttcttcgtga gcaattggat gaagttttag
    19261 atacgcttac tgaccgtgaa gagaacgttc ttcgcctacg ctttggcctt gacgatggta
    19321 aaatgcgtac gttagaggac gtaggtaaag tctttaatgt tactcgtgag cgcattcgac
    19381 agattgaagc taaagccctt agaaaacttc gccatcctag tcgtagtaaa caattaagag
    19441 actttataga ggactaaaat cgtccagtgg acgattttag gtcgttcctt tgaaataaga
    19501 aaggagccaa aatcctaagt gacacttatc agcggtacat ctacaaatta gaaatcggac
    19561 cgaatgtggt gggtattttt aagattggac ttgatatctt aaacaagccc agagggcaat
    19621 tcctctaaat aggcaaagct ttagtggttt tttacttatc tacgacatat tcaaaaaatg
    19681 aaaggaaagc catgtctgat acaccaaaat atacacaaga tcaggtgata gctatcaaga
    19741 atagaattct tgaagcttta gaaactgtta ttgatcccga gctaggtatt gatgttgtta
    19801 atctaggctt gatttatgaa attcggttta atgataacgg ttatacagag attgatatga
    19861 cactcacaac aatgggttgt cctttggcag acttgttgac agattacatc catgatgccc
    19921 tgcaagatgt gccagaagtc actaagactg aggtcaaatt agtctggtac cctgcttgga
    19981 cggttgataa aatgagccgc tatgctagga ttgcgctggg tattcgctaa tcattgatag
    20041 taaagggatg aaatattccc ttttttgatg tagaataaaa ggaaatacag gtgaaagcct
    20101 ttggtgaatg ttagagaaca ctaagatact gaaaaaaagt gttctatcta tggcaaaaag
    20161 gagaactgat gattttaatt acaggaagca atggtcaatt agggacagaa cttcgatact
    20221 tattagatga acgaggtgtt gattatgtag ccgttgatgt cgcagaaatg gacatcacaa
    20281 atgaagacaa agtcgaagct gtttttgcgc aggtcaagcc aacattggtc tatcattgtg
    20341 ctgcttatac ggcagttgat gcagcagaag acgaaggaaa agccttgaat gaggctatta
    20401 atgtaacagg ctcagaaaat attgccaagg cttgtggaaa atatggggct acccttgttt
    20461 acatttcaac agactacgta tttgatggca ataaaccagt cggtcaagaa tgggtagaaa
    20521 cagatcgtcc agaccctaag acagaatatg gccgtacaaa acgtttagga gaactagctg
    20581 ttgaacgata cgcagagcat ttttatatta tccgtactgc ttgggtattt ggaaattatg
    20641 gtaaaaactt tgtctttacc atggagcagt tagcggaaaa tcactcccgt ttgactgttg
    20701 tcaatgacca acacggtcgg ccaacgtgga caagaacctt ggcagaattc atgtgttatt
    20761 tgacagagaa tcaaaaagcc tttggttact atcacttgtc aaatgatgct aaggaagaca
    20821 ccacttggta tgattttgcc aaagaaatct taaaagacaa ggctgttgaa gtggtgccag
    20881 ttgattcatc agctttccca gcaaaagcca aacgtccttt aaattcaacc atgaatcttg
    20941 ataaggcaaa agcaacaggg tttgttattc caacatggca agaagccttg aaggcatttt
    21001 accaacaagg actgaaaaag taagtattct aaaaagagtt ggctttctaa ggccaactct
    21061 ttttcatggg tttaaggtcg cattagcctt ctaattgtgg tataatatca ctgattatat
    21121 tttagaatgg ggtagtatgc aatgcaggat gtttttatca ttggtagcag agggttacca
    21181 gcgaaatacg gtggctttga aacctttatc gaagagttga ttagtcatca atcatctaaa
    21241 aacattcgtt atcacgttgc ttgtttaagc gatacgaagc ataaggttca ttttgattat
    21301 aagggggcag attgctttta ccttaatccc ccaaaacttg gtcctgctag agttattgct
    21361 tatgatatga tggcaattac ctatgccctg tcttatagcg accaacacca gattcagaac
    21421 cctatttttt atgtgttggg caatactgta ggcgctttta ttgcgccatt tgtgaagcag
    21481 attcacaatc gaggtggacg cttttttatc aatccagacg ggttagagtg gaaacggtct
    21541 aaatggtcaa aaccagtgca ggcctacctg aagttttccg aaaagcaaat gactaggcag
    21601 gctgatttgg tcatttcaga taatattggc attgaccgct accttaaaca ggtttatcct
    21661 tggtctaaaa catgttttat tgcttatgga acgcagacac aaccttcacg tttgacaaca
    21721 gcagatagca aggtcagagc ttattttcaa acctttgata ttagagaaaa ggattactat
    21781 ctcattttag gacgctttgt tcctgaaaat aattacgaaa ctgctattaa agaatttatg
    21841 gcttcctcaa ctaagcgtga tttagtgatt atttgtaatc atgaaggcaa tgcttacttt
    21901 aagcaattac ttgctgagac agagtgtgat aaagacccac gcattaaatt tgttggtacc
    21961 ctttatgata aagaactatt agcctacatt cgagaacagg cttatgccta tatccatggt
    22021 catgaggtag gagggactaa tccaggcctt ctagaagcac tagcccatac caatcttaat
    22081 ttggttttag gagttgattt taaccagtgg gtggctaagt ctgctgcgct gtattggtcc
    22141 aagcaaaaag ggcaattagc agagctgatt aaccaagttg atgcaggttt tgatagtgat
    22201 catctgggca aagaagccaa agctattatt caagaacatt acacttggga aaaaattgta
    22261 ggggagtacg aggctttatt tttaaatgaa cattaatatt ttactatcca cctacaatgg
    22321 agaacgcttc ttagcagaac aaattcaaag tatccaaagg caaacagtta acgactggac
    22381 cttattgatt agagatgatg gttcaactga tggcacccag gatattattc gcacatttgt
    22441 caaggaagac aaacgaattc agtggatcaa tgaggggcag acagaaaatc tgggagttat
    22501 taagaatttt tacaccctct taaagcacca aaaagcagat gtctattttt tcagtgacca
    22561 agatgatata tggttagaca ataaactgga agtgacctta ttggaggctc aaaaacatga
    22621 aatgacagct cctttattgg tttatacaga cctcaaagtg gtaacccaac atttagctat
    22681 ttgccatgac agtatgatta agacccaatc tggtcatgca aacacaagcc tacttcaaga
    22741 attaaccgaa aataccgtaa caggcggcac aatgatgatt actcatgctc tggctgagga
    22801 atggaccact tgtgacggtt tattgatgca tgactggtat ttagctttac tagcttctgc
    22861 tactgggaaa ttagtttacc ttgatattcc aacagaatta tatcgtcagc acgatgctaa
    22921 cgtgttggga gctagaactt ggtctaaacg catgaaaaat tggttaaacc cccatcattt
    22981 agtcaacaaa tattggtggt tgattacttc aagccaaaaa caggctcaat tactattaga
    23041 tttaccatta aaaccaaatg accatgaatt ggtaacggcc tatgtttctt tattggatat
    23101 gccttttacc aaacgcttag ctaccttgaa aaggtacggt tttagaaaaa atcgcatctt
    23161 tcacaccttt atttttcgta gtttagttgt taccttattt ggttacagga gaaagtaaga
    23221 atgaattttt taacaaagaa aaaccgtatt ttactgagag aaatggtaaa aacggatttt
    23281 aaattacgct atcaagggag cgcaattggc tatctatggt ctatcttaaa accgcttatg
    23341 atgtttacga ttatgtactt ggtatttatt cgttttcttc gcctgggtgg aaatgtacct
    23401 cattttccag tagcgctttt attggcaaat gtcatctggt cttttttttc agaagcaact
    23461 agcatgggaa tggtatctat tgtatctcgg ggagacttgt tgcgaaaatt gaacttttct
    23521 aagcacatca ttgttttttc ggcagtgtta ggagctttaa ttaattttct tattaatttg
    23581 gttgttgttt taatttttgc gttgataaat ggtgtgacta tatcagggta tgcttatctc
    23641 tctctttttc tttttataga attagttgtt ttagtgcttg gaattgcatt gttattgtcg
    23701 aatgtctttg tttattatcg tgacttagct caagtctggg aagtactatt acaagcaggt
    23761 atgtatgcca ctccaatcat ttatccgatc acttttgttt tagacagcca ccctttggcg
    23821 gcaaagttgt tgatgctaaa tccagtagca caaatgattc aagattttcg ttatttattg
    23881 attgacaggg ccaacgtaac gatttggcag atgtcaacca attggtttta cattgttatt
    23941 ccatatttag taccatttgt tatattattt attggcatct ttgtctttaa gaaaaatgcc
    24001 gatagatttg cggagattat ttaatgatta atagagaaat tgcagtaaaa gtacagcatg
    24061 ttagtaaaac atttaaactg cctacagaag caactaaaag ttttcgcacg actctggtta
    24121 atcgcctaag agggattaaa ggatttactg aacaacatgt gctaaaagat attaactttg
    24181 atgtttataa aggcgatttt tttggaattg ttgggcgtaa cggctcggga aaatcaacgc
    24241 tccttaaaat tatttcccag atctatgttc cagaaaaagg acaggttaca gtagatggga
    24301 agatggtttc ttttatagag cttggagtgg gattcaatcc agaattaaca ggacgagaaa
    24361 acgtctatat gaacggcgcc atgctgggat ttaccaaaga cgaagttgat gatatgtaca
    24421 atgatattgt tgattttgca gagttgcatc attttatgaa tcaaaaatta aaaaattatt
    24481 cttctggcat gcaggtacgt ttagcatttt cagtggctat taaagcccaa ggtgatgttc
    24541 ttattttaga tgaggtgctt gctgtaggag atgaagcttt tcagcgaaaa tgtaatgatt
    24601 attttatgga aagaaaagac agtggtaaga cgactatttt agtgacacat gatatgggag
    24661 ctgttaagaa gtattgtaac cgtgcagttc ttattgaaga tggtcttgtt aaagcatatg
    24721 gagaaccatt tgatgttgct aatcagtata gtgtagataa tacagagaca gctgaggatg
    24781 caatgaatgc tgaaaaaata tctgtatctg atattgccaa agatttgaaa gtgtcattaa
    24841 tctcaaatcc aagaataaca ccaaatgaca caatcacatt tgaagtttcc tatgaagttt
    24901 taaaagatga ttttacctac attgcctttt ctttaacgga tattgataga aacatttggg
    24961 tttacaacga caattcttta gattatccaa cacaaggtat aggtagaaaa tgcatttcct
    25021 accaatgtca actatctcaa cttaatgata taaaactaaa attagaagta actgtccgag
    25081 ataagaacgg tcagatgcta ctcttttcaa cagcagaaca atcaccccag atagtgattc
    25141 aaagaaacga tattgatcaa gatgatctgt cagctctaga ttcagcaagt ggcttgtatc
    25201 aacgtaatgg gaagtgggtt tttcattaat gagtaatagc tagaagggaa tttatgtata
    25261 aagtttcaat tatttgcacc aattataaca aagctccttg gatatctgat gcacttgaca
    25321 gttttttaag ccaagtgaca gattttgagg ttgaaattat tgttattgat gatgcttcta
    25381 cagatgactc acgagagatt ttaaagagtt atcaaaaaaa gtcttcagga aaaattaaat
    25441 tactctttaa cgaaactaat attggaataa caaagacttg gataaaagca tgcctttatg
    25501 caaaaggcaa atatattgct agatgtgatg gtgatgatta ctggacggat agttttaaac
    25561 tccaaaaaca agttgatgtc ttagaagctt ccaaacggtc acgatggtgt aatactgatt
    25621 ttgactttgt aaatagtcaa ggcgacttat tatatgctaa tgctttttca tctggtcata
    25681 cacctttgac agatacttac gaaaaagttt tagccttaaa agggatgacg atggcatcga
    25741 catggttagt tgatgctgat ttaatgagac aagtaaacca aaaaatcaat gtagatacac
    25801 cagacgatac ttttgatatt caactagagt tatttcaact gactcaactg acctatatta
    25861 aagactccac gacggtttat cgcatgacaa ccgattctga ttcaagacct actgatacac
    25921 caaaaatgat tcatcgtatt caaaaactac ttgatactca gttaaattac ttaaaaaagt
    25981 ataatcaggt agatacaaaa gaagtgtcta aactattatt acaacaagat gctaagcaag
    26041 aaatacgaat tcatgagttg agttgcttta ttcaagaatt acaacaaact atcgtagata
    26101 aaacaaagca gcaagaaaca cgtgaagtgg agttgcaaaa tgtcatagaa gaacaaaaaa
    26161 atcaactatc tgaattaaga caacaatacc atgccattat taattcacgt caatggaaat
    26221 acacgtctaa gctcattgct tttattagga gaaaaaaatg aatcgtattt tattatatgt
    26281 tcacttcaac aaatacaata aaataagtgc acatgtttac tatcaattgg aacaaatgag
    26341 atcactgttt tctaagattg tttttatctc aaatagtaaa gtgagtcacg aagatttaaa
    26401 acgtctcaaa aaccactgtc ttattgatga gtttttgcaa cgcaaaaata aaggttttga
    26461 tttttctgca tggcacgatg gcttgattac tatgggattt gacaagttgg aagagtttga
    26521 ctcattgacg attatgaacg atacttgttt tggtcctatt tgggagatgg ctccttattt
    26581 tgaaaatttt gaagaaaaag agacagttga cttttgggga attactaata atagaggtac
    26641 aaaaactttt aaagaacatg tccaaagtta ttttatgacg tttaaaaatc aagtcattca
    26701 aaacaaagtt tttcaacaat tttggcaatc gataatagaa tatgaaaacg ttcaagaagt
    26761 gattcagcat tatgaaacgc aattaacatc cattctctta aatgaaggct ttagttatca
    26821 gacggtcttt gatactagaa aagctgagtc gtcattcatg ccacatccgg atttttcata
    26881 ttataatcca acagcaattc taaaacacca tgtgcctttt ataaaagtaa aagctattga
    26941 tgctaaccag catatcgctc cttacttact gaatctgata cgagaaacaa ccaattatcc
    27001 tatagatctt attgtttcac atatgtcgca aatctctttg ccagatgcta agtacctttt
    27061 atctcaaaaa tacctaaact gccaacggtt agcaaaacaa acttgtcaaa aggtagctgt
    27121 tcatttacat gttttttacg ttgatttgct agatgaattt ttaacagctt tcgaagactg
    27181 gaacttccat tatgatcttt ttattacaac agatagtgat atcaaaagaa aagagatcaa
    27241 agaaatactt caaagaaaag gtaaaactgc tgatatacgc gttacgggaa atagaggaag
    27301 agatatttat ccaatgttat tactaaaaga taaactttct caatatgatt atattggtca
    27361 tttccatacg aaaaaatcaa aagaagctga tttttgggca ggagaatctt ggcgaaaaga
    27421 attgattgat atgctcgtga aaccagcaga tagtattctt agcgcttttg agacagatga
    27481 tattggtatt ataatcgcag atattccaag tttttttaga tttaataaga ttgtcaatgc
    27541 ttggaatgag catttaatcg ctcaagaaat gatgtctttg tggagaaaaa tggatgttaa
    27601 aaaacaaatt gattttcaag ctatggatac atttgttatg agttatggaa catttgtatg
    27661 gtttaaatac gatgctctaa aatcactttt tgatttagaa ttaactcaaa atgatattcc
    27721 aagtgaacct ttaccacaaa actctatatt acatgcgatt gagcggttac ttgtctatat
    27781 agcgtggggg aattcttatg attttaggat tgttaaaaat ccctatgagt taacaccttt
    27841 tattgacaat aaactgttaa atttacgtga agatgaagga gctcatacct acgttaactt
    27901 taatcaaatg ggcggtatca aaggagcatt gaaatatatt attgttggtc ccgctaaagc
    27961 aatgaagtat atattcttgc gtttaatgga gaaacttaaa tgattaaaga cacattttta
    28021 aaaaccaatt ggttaaatat tagtcaccat attatccttc ttgttttcgg tttttatttc
    28081 agtttttaca gtttggcgaa agaactagta agctccacgg cacaaccggt aaactattat
    28141 actcatttac taaatgtttc ttttgtggga tatattatat cactgattgg attatcttat
    28201 tatttgagtc gccaagttag tcgacagttg tttttgaaaa ctagttttat tgtgatatct
    28261 tatctaattg tcagctattg ggtacaaata acacagcacc tgaatgataa acggtttgat
    28321 atctggtcat taactaaaaa tcaattttat caatttcaag ctctacctta tttactcatt
    28381 attttagtga tggccacttt aataaaaata ttggtagcat attttgcaat agaaaaagat
    28441 agatttgggc tattaggcta tcaaggtaat actttttctg tagctctgat tttagcagtt
    28501 gtgccaatta atgacataca tctgttaaaa ctaataagtt ctcgattttc tgaattagta
    28561 acagcaggta atagccaaat tgcactgtta aaaataagtg gactgttgat agttttactt
    28621 gtcatatttg caacaatcat atacgtggtt ttaaatgctc taaaacacct taagtcaaat
    28681 aaaccttcat tttcagtagc agctactact agtttgtttt tagcattagt ttttaactat
    28741 acgttccagt atggagtaaa aggtgatgaa gcattgctag gatattatgt tttccctgga
    28801 gctactcttt ttcagatagt agctattaca ctagttgctc ttttagcata cgtgataacg
    28861 aatagatatt ggccaactac cttctttttg cttattctgg gaacaattat ttctgttgtt
    28921 aatgatttaa aagaatcaat gagaagcgag ccgttattag taactgattt tgtttggtta
    28981 caagaattag gtttagtgac aagctttgtt aaaaaatcgg tgattgtaga aatggttgta
    29041 ggacttgcta tttgtattgt ggtagcttgg tatctacatg gccgagtttt agcagggaaa
    29101 ttatttatga gccctgtcaa acgggcaagt gctgtattag gtttatttat tgtatcttgt
    29161 agtatgttaa taccattttc ttatgaaaaa gaaggtaaaa tattatctgg tcttccgatt
    29221 atttcggctt taaataatga taatgatata aactggttag gtttttcaac aaatgctagg
    29281 tacaaatctt tagcatatgt ttggacaaga caggtgacca agaaaataat ggaaaaaccg
    29341 acaaattata gccaagaaac aatagcgagt atcgctcaga agtaccaaaa attagcagaa
    29401 gatattaata aagacagaaa aaataatatt gctgaccaaa cggttattta tcttttaagt
    29461 gaaagcttgt cagatcctga tagagtatca aatgttactg ttagccacga tgttttacct
    29521 aatatcaagg caatcaaaaa tagcacaact gcgggactca tgcagtcaga ctcctacggg
    29581 ggtggaacgg ctaacatgga gtttcaaacg ttaacaagct taccttttta taatttttct
    29641 tcttcagtat ctgttcttta ttcagaagtc tttcctaaaa tggccaaacc tcatacgatt
    29701 agtgagtttt accaaggaaa aaatcgtatt gcgatgcatc ctgctagtgc taacaatttt
    29761 aatagaaaaa cagtttatag taatttaggt ttttccaaat tcttagctct atcgggttct
    29821 aaggataagt ttaagaacat tgaaaatgtc ggtttattga ctagcgataa aactgtctat
    29881 aataatattt tatctttaat taatcctagt gaaagccaat ttttctcagt tattacaatg
    29941 caaaatcata ttccttggtc atccgattat cctgaagaaa ttgttgctga aggaaaaaat
    30001 ttcacggaag aagaaaatca caacctaaca agttatgctc ggttattatc gtttactgat
    30061 aaggaaacaa gagcattttt agaaaaatta acacaaatta acaagcctat cacagtggtg
    30121 ttttacggag atcatttacc cggtttatat cctgatagtg cttttaacaa gcatattgaa
    30181 aataaatacc ttactgatta ttttatttgg agtaatggta ctaacgagaa aaaaaatcat
    30241 ccgcttatca actcaagtga ttttactgca gctttatttg agcatactga ttcaaaagta
    30301 tcaccttact atgctttgtt aacagaggta ctgaataaag ctagtgtcga taaatcacca
    30361 gatagtcctg aagttaaagc tattcagaat gatttaaaaa atatccaata cgatgtgact
    30421 ataggaaaag gttacctttt gaaacacaaa acttttttta agatatcacg ttaagaaaaa
    30481 tgctaggctg tccgagtata gacgagcatc aaggtttggt aatttgctca aatgattgtc
    30541 aacagagtgt ctaggaccag gtttaaaaga ttataattct taaggtctta ttcgtttata
    30601 aaaaatgaat actcttttaa aatcttaatt gaaatgaata ggagaagttt tcgtgaaaaa
    30661 gttaatcatt attcctgctt acaatgaaag cagtaatatt gtcaatacta tacgtactat
    30721 tgaatcagat gccccggatt ttgactatat cattattgat gattgctcaa cggataatac
    30781 gttagcaata tgtcaaaaac aggggttcaa tgttatttct ttgcccatta acctgggaat
    30841 tggcggtgcg gtgcaaactg gctatcgtta tgcacaaaga tgtggatatg acgttgcagt
    30901 tcaagtagat ggagatggtc agcacaatcc atgctatttg gaaaaaatgg ttgaggtatt
    30961 agttcaatct tcagtaaata tggtaattgg atcacgattt atcacaaaag aagggtttca
    31021 gtcatcattt gctcgacgta tcggtataaa gtattttact tggcttattg cgctactaac
    31081 aggaaaaaaa ataacagatg caacgtcagg tctaaggtta attgaccgtt cattgattga
    31141 acgttttgct aatcattatc cagatgatta tcctgaacct gaaacagttg ttgatgtatt
    31201 ggttagtcat tttaaagtga aagaaattcc tgttgtaatg aatgagcgac aaggcggtgt
    31261 gtcatctatc tcgttgacga aatcggtcta ttatatgatt aaagtgactt tagctatttt
    31321 agttgttaga ttgaaaggaa atcgttaaaa tgacggtaac agccagttta tttataagtt
    31381 ttattgtatt aacctttgtt ttctttttga ttaacttaat caaaaaagac aaactagcga
    31441 ttaagtactc tttattgtgg tttattttag ctttattaat tttactattt acgtggttac
    31501 ctaacatatt aaataaaatg tctcacttcc tgggtattca ttcaccaacc aatatgttat
    31561 tctttttagg tttttgtttg agtttagcta ttattttttc actgactaat aatatctcac
    31621 ttcaaaatga taaagtaaaa cgtctgaccc aagaagtggc ccttatgaaa aaagagaaaa
    31681 ccaatgatta atccttcaaa acaaaaccaa acgatttttt tatggaatat gttaggaagt
    31741 ttatcaacag ctgtaatatc agttatatta cttatggtgg ttactaggtt actaacttcg
    31801 gctgattcag atatttacgc ctttgcctat tcttttgcta atatgatggt agttgttgga
    31861 ctttttcagg ttcgtaatta tcaagcaaca gatattaatg aaaaatattc ctttagtcag
    31921 tacttagtgg caagactgat gacttgttta ttaatgttag ccataacagt aatttattta
    31981 acgttaacta agacagatag ctacaagagt acaattgtct ttctagtctg tttctataga
    32041 tcgacagatg ctttttcgga tttatatcag ggaatgttcc aacaacatga acggctggat
    32101 attgcaggta aatcgctagc ctacagaaat actcttattt ttatggtgta cacagcaata
    32161 atattatatt ccaaaaatct cactttagca ttagtagctg tctgtatagt ttcatta
//
LOCUS       DATTYN010000019        31973 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.19, whole genome shotgun sequence.
ACCESSION   DATTYN010000019 DATTYN010000000
VERSION     DATTYN010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31973
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.19"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            117..758
                     /locus_tag="VB649_001128"
     CDS             117..758
                     /locus_tag="VB649_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEP1670086.1"
                     /translation="MKDLLKQYQAKPLGEEKRYAVFLPLILVNDDWHVLYEVRSQHIS
                     QPGEVSFPGGQVENQETLQEAAIRETVEELTVDASQIQLWGEIDYLVQSSRTIHCFVG
                     QLVVDDWESIQPNEEVDKVFTVPLRQLLVTDPVYYHLEATPIETTDFPFDRIRNGKCY
                     QFSQEYRSIPFYENLEETIWGMTAQFTKCLTDILNDESIAKKNPLDIEKSKGR"
     gene            complement(805..1647)
                     /locus_tag="VB649_001129"
     CDS             complement(805..1647)
                     /locus_tag="VB649_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEP1670087.1"
                     /translation="MVSFISRVFKGMIIALGFILPGVSGGVLAAILGIYERMISFLAH
                     MRDNFIENVLFFLPVGIGGILGIALFSFPVEFLLKHYQVIVLWGFAGAIVGTIPSLIK
                     ESTKQSQRDKVDWLWLVLTFVISGLGLYFLNDLIGTLPANFLTFILAGALIALGVLVP
                     GLSPSNLLLILGLYGPMLIGFKSLDLLGTFLPIAIGGVLAILAFSKSMDYALQHHHSK
                     VYHFIIGIVLSSTLLILIPNSSSPESISYSHAGILTWLMAVVLFALGIWLGLWMSQLE
                     EKYK"
     gene            2064..2108
                     /locus_tag="VB649_001130"
                     /pseudo
     CDS             2064..2108
                     /locus_tag="VB649_001130"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2115..2396
                     /locus_tag="VB649_001131"
     CDS             2115..2396
                     /locus_tag="VB649_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP1670088.1"
                     /translation="MLSKSLQVPLEQLIAEDIPKMTLIIKDEEIKQCDRNTHIMLFGT
                     LLIAISIYPIMSWLGWWGYGPVAILWLIIMRSALRIERFKKTYDVQTYR"
     gene            complement(2872..3474)
                     /locus_tag="VB649_001132"
     CDS             complement(2872..3474)
                     /locus_tag="VB649_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670089.1"
                     /translation="MTTKTYFMRSFNLILYLLLIAPICYVFGWLFNLVSVQLSTVTFV
                     NLDTVKNVTDTISSVCYGFALISLLLALLSGLKMIQRLNTDSLGNYCQSIYRTFLLRH
                     FLFQRERVQKVSNFEHQTVTTINPIHNGFNRAVRKCIVDIRKDAITVFLKVPRDQQGQ
                     KILKDTGVQLKEEIVIQHTDYYFSSPVRVRNQLWFIGQKR"
     gene            complement(3471..4223)
                     /locus_tag="VB649_001133"
     CDS             complement(3471..4223)
                     /locus_tag="VB649_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEP1670090.1"
                     /translation="MAIPDLDKFSSSLQQGKIPVIKHFELNLDKGSHWAIAGNSGSGK
                     PYALTYFLSVLKPMSGLIIIDPKFDTPSQWARENKIAVIHPVENHSKSDFVSQVNEQL
                     NQCATLIQKRQAILYDNPNHQFTHLTIVIDEVLALSEGVNKNIKEAFFSLLSQIALLG
                     HATKIHLFLGSQRFDHNTIPISVREQLNVLLQIGNINQKTTQFLFPDLDPEGIVIPTG
                     HGTGIIQVVDNEHSYQVLPLLCPTYYTKRGIL"
     gene            complement(4289..5062)
                     /locus_tag="VB649_001134"
     CDS             complement(4289..5062)
                     /locus_tag="VB649_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670091.1"
                     /translation="MLYLNTQTDSDYKEIIFGDIAKFVENMFYHYFSSILFRDLETVD
                     KRMYSFSDDDLISIQSSCLRLSKTFANFNIQRKNFLASDETEMDTFHKKDDIDMTVGE
                     KSYNLARSFRTSTINELTVFNFEEMFDIIWLMLGDNLIKSFEVNVCGILFELNGNGIP
                     STFRQENIDPLINKWWYDNVSTEIIPNLIKKLKENPLFNIGFLVDDILERMYKENIPK
                     SYLTSVPLVISKKARSTLSIKSNGSQKIDKSKFAQILSL"
     gene            complement(5256..5594)
                     /gene="cadX"
                     /locus_tag="VB649_001135"
     CDS             complement(5256..5594)
                     /gene="cadX"
                     /locus_tag="VB649_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cd(II)/Zn(II)-sensing metalloregulatory
                     transcriptional regulator CadX"
                     /protein_id="HEP1670092.1"
                     /translation="MKKDSICQVNVINQQNVTTATNYLEKKKVQKSLRILSKFTDNKQ
                     INIIFYLLTVEELCVCDIACLLNLSMASASHHLRKLANQNILDTRREGKIIYYFIKDE
                     EIRDFFNQLG"
     gene            complement(5606..6220)
                     /locus_tag="VB649_001136"
     CDS             complement(5606..6220)
                     /locus_tag="VB649_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEP1670093.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGLKVLLLGDSDGEAIAKEGLRK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGEILEKYSRWFIAVVYLGLGIYILIENNSFDMLWAVLG"
     gene            complement(6501..6650)
                     /gene="rpmG"
                     /locus_tag="VB649_001137"
     CDS             complement(6501..6650)
                     /gene="rpmG"
                     /locus_tag="VB649_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEP1670094.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVT
                     FTEVK"
     gene            complement(6666..6848)
                     /gene="rpmF"
                     /locus_tag="VB649_001138"
     CDS             complement(6666..6848)
                     /gene="rpmF"
                     /locus_tag="VB649_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEP1670095.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSL
                     KGYYKGRKIAKANEAK"
     gene            7068..8348
                     /locus_tag="VB649_001139"
     CDS             7068..8348
                     /locus_tag="VB649_001139"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEP1670096.1"
                     /translation="MKLQKPKGTQDILPGDAAKWQYVESVARDTFSQYNYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGAECFGAANPATDVETIAMAYHLFEKLGIKD
                     VTLHLNSLGSPESRSAYRQALIDYLTPMRDQLSKDSQRRLDENPLRVLDSKEKEDKLA
                     VEKAPSILDYLDEESQAHFEAVKAMLEALDIPYVIDTNMVRGLDYYNHTIFEFITSVE
                     GSDLTICAGGRYDSLVGYFGGPETPGFGFGLGLERLLMIIEKQGLALPIETEMDVYLA
                     VLGDGANSKALELVQAIRRQGFTAERDYLGRKIKAQFKSADTFKAKLVMTLGESEVEA
                     GKAVIKNNRSRQEVEVSFEDMMTNFANISEQLLS"
     gene            8686..10434
                     /gene="aspS"
                     /locus_tag="VB649_001140"
     CDS             8686..10434
                     /gene="aspS"
                     /locus_tag="VB649_001140"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEP1670097.1"
                     /translation="MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTI
                     LNTAKTTPFEIKDDVEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSY
                     DVAMNSYGSDKPDTRFKMLLQDLTVTVKGIDFKVFSEAPAVKAIVVKGNADRYSRKDI
                     DKLTEFAKQFGAKGLAWVKVTDGQLAGPVAKFLTAIETELSSQLKLAENDLVLFVADT
                     LEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPT
                     PESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANAQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SENQLEELSLQIESHD"
     gene            10427..11368
                     /locus_tag="VB649_001141"
     CDS             10427..11368
                     /locus_tag="VB649_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP1670098.1"
                     /translation="MIKKTTYKKKVKYVISRGAKKVGLLHALRSISREKYAEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVFSALSHRLLGYDFPIAFAFYLINIPLLI
                     LAWYKIGHQFTIFTFITVSMSSFFIQIIPQVTLTTDPLINAIFGGLVMGMGIGTGLKS
                     RISSGGTDIVSLTLRKRTGKDVGSLSLMVNGAILAFAGILFGWQYALYSMVSIFVSSR
                     VTDAIFTKQKKMQATIVTSHPERVIHMIHKRLHRGVTSINDAEGTYKHEQKAVLITIL
                     TCEEYPEFKWLMLKTDPQAFVSVAENVRIIGRFVEDD"
     gene            11388..12266
                     /locus_tag="VB649_001142"
     CDS             11388..12266
                     /locus_tag="VB649_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP1670099.1"
                     /translation="MSIDQRLQLKKFCFIILGAAIYAFAFVYFYMANRIAANGLAGLT
                     LVGKALFEIDPSLIGYLINLPLVLLGARCFGKRVMVYTVTGVLSLYFFVWLFQRFPLV
                     VDLDHDNLVVSLMAGIIGGLGGGLVFRNGGTIGGADIIAKLLEDKLGLQLNQALLGID
                     LFVMIVSLTYISLPQMMYALIASFMYGQIVRLVQQGGYSARGIFIVSEQAEKIARFIM
                     EELGRGVTYLTGEGAYSGRRKKVIYVALGRRDIRELKAFLTQVDPNAFITYFDVNEVN
                     SPEFLTIKSKYHKKRK"
     gene            12309..13181
                     /locus_tag="VB649_001143"
     CDS             12309..13181
                     /locus_tag="VB649_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP1670100.1"
                     /translation="MAHHDKLTKLLKLFLIALGVAIYTFGFVNFNMANALAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFILGAKIFGKRSLALTIYGTVLMSAFIWMWQKVPI
                     ELGLENDMMLVAVVAGLFSGIGSGIVFRYGATTGGTDIIGRIAEEKFGAKLGQTLLLV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKHSEAAAQAI
                     LTEINRGVTYLKGQGAYSGNDYNIMYVTLNPTEVREVKRILAGLDPDAFISIIDVDEV
                     ISSDFKIRRRNYDK"
     gene            complement(13208..13516)
                     /locus_tag="VB649_001144"
     CDS             complement(13208..13516)
                     /locus_tag="VB649_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEP1670101.1"
                     /translation="MPSEKEILDALSKVYSEQVIQADDYFRQAIFELASQLEKEGMSS
                     LLATKIDSLINQYILTHQFDAPKSIFDLSRLVKTKASHYKGTAISAIMLGSFLSGGPK
                     "
     gene            complement(13604..15295)
                     /locus_tag="VB649_001145"
     CDS             complement(13604..15295)
                     /locus_tag="VB649_001145"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEP1670102.1"
                     /translation="MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFS
                     LAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSD
                     YAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLE
                     DGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEILDLLEAKNLL
                     VESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINR
                     AASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMA
                     KFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM"
     gene            15586..16023
                     /gene="argR"
                     /locus_tag="VB649_001146"
     CDS             15586..16023
                     /gene="argR"
                     /locus_tag="VB649_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEP1670103.1"
                     /translation="MNKMERQQQIKRIIQAEHIGTQEDIKNHLQKEGIVVTQATLSRD
                     LREIGLLKLRDEQGKLYYSLSEPVATPFSPEVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDILGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            16020..16372
                     /locus_tag="VB649_001147"
                     /pseudo
     CDS             16020..16372
                     /locus_tag="VB649_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
     gene            16359..18914
                     /gene="mutS"
                     /locus_tag="VB649_001148"
     CDS             16359..18914
                     /gene="mutS"
                     /locus_tag="VB649_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEP1670104.1"
                     /translation="MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAA
                     QLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
                     VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELT
                     AAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLY
                     WLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYD
                     IERLSSRVSFGKANPKDLLQLRHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEY
                     LIRTAIDPDAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQESGINNL
                     KIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFNDNHVIT
                     IQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQM
                     GSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDE
                     LGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEK
                     DGDVTFLHKIAEGPADKSYGIHVAKVAGLPKSLLKRADEVLTRLETQSRSTEIMSVPP
                     QVESSSAVRQGQLSLFGDEEKAHEIRQALEAIDVMNMTPLQAMTTLYELKKLL"
     gene            complement(19312..19923)
                     /locus_tag="VB649_001149"
     CDS             complement(19312..19923)
                     /locus_tag="VB649_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670105.1"
                     /translation="MVKKKLVMIAAFCLSMCAVSVKAEGTAVNTQFTTQGYLSEVTVS
                     PFNVGDQQISVHVGSFGYVFASVNDKKIEVPNIKHKVTCDKTKTWIYSPDCYEREWET
                     SGYRAGEDGNYTVKLKKPLVEGDKVTLSFADGGNLYFGQLVFEDEKTQNERLQKEREA
                     EEQQYAEELFKRSIEEEAKKTWHQRLSDSIQDQWWNFKGWLRG"
     gene            complement(20093..20254)
                     /locus_tag="VB649_001150"
     CDS             complement(20093..20254)
                     /locus_tag="VB649_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP1670106.1"
                     /translation="MTVGDKIKTIRLNLGETMEEFGKRFGTYKSTVNNWEKGRNLPNR
                     NSLLRLIHL"
     gene            complement(20288..20494)
                     /locus_tag="VB649_001151"
     CDS             complement(20288..20494)
                     /locus_tag="VB649_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670107.1"
                     /translation="MTQITLKAARINAGYTLKQVAGAVGKNPQTISKYEKDSSDISLG
                     LLQKLSSLYGVTIDNLFLGKKVRK"
     gene            20648..21415
                     /locus_tag="VB649_001152"
     CDS             20648..21415
                     /locus_tag="VB649_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP1670108.1"
                     /translation="MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTI
                     TGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSNNIETNSNIIPSTLQKVTSTLSQ
                     LEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
                     PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVIND
                     SGAFLHSLNDKYDDILIDRDSDFRIIGEVIGSFTSKS"
     gene            22478..23332
                     /gene="dinD"
                     /locus_tag="VB649_001153"
     CDS             22478..23332
                     /gene="dinD"
                     /locus_tag="VB649_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
                     /protein_id="HEP1670109.1"
                     /translation="MNGLQHYDELAFENIKHIDENGVEFWYARELQTVLEYAKWDNFL
                     NVIERAKIACENTGNPVAMNFPEVSKIVQLPLGDREIKDYKLSRYACYLIVQNGDPRK
                     EVIALGQSYFAIKTRQQELADNFNKLDEEHKRLAIRQEMKEHNKSLAEAAKMSGVTNY
                     GKFQNFGYKGLYGGMSMQDIHDRKELEKGQSILDYMGSAELAANLFRATQTDEVLRNR
                     QIHDENLANDTHFNVGRTIRKTMQKLGTTMPENLPTPQESIQDLKKKHKQLDKQPDDN
                     QLSLFDDM"
     gene            23588..24733
                     /locus_tag="VB649_001154"
     CDS             23588..24733
                     /locus_tag="VB649_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP1670110.1"
                     /translation="MKITEHKKKNGTIVYRASIYLGIDQMTGKRVKTSITGRTRKEVN
                     QKAKHAQLDFLSNGSTIKRKVVIKTFKELSHLWLETYKLTVKPQTYDATVTRLNRHIM
                     PTLGNMKVDKITASDIQMLINRLSKYYVNYTAVRSVIRKVLQQGVLLGLIDYNSARDI
                     ILPRKQPNAKKKVKFIDPSDLKSFLEHLETSQHKRYNLYFDAVLYQLLLSTGLRIGEA
                     CALEWGDIDLENGTIAINKTYNKNLKFLSTAKTQSGNRVISVDKKTLRSLKLYQMRQR
                     QLFNEVGARVSEVVFATPIRKYFNASVRQSALDTRCKEAGIERFTFHAFRHTHASLLL
                     NAGISYKELQYRLGHANISMTLDTYGHLSKDKEKEAVLYYEKAMNNL"
     gene            24828..26810
                     /gene="mutL"
                     /locus_tag="VB649_001155"
     CDS             24828..26810
                     /gene="mutL"
                     /locus_tag="VB649_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEP1670111.1"
                     /translation="MTKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQVTDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKITIKTATKEVTHGSLLIATGGEIETLEAISTPTGTKIKVENLFYNTPARLKY
                     MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTT
                     KKMLVISNADLDFEVSGYVSLPELTRANRNYMTILVNGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALISTAISESLKEQDLIPD
                     ALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVSEKIPETDFYSGAV
                     DNSIKVEKAELLPHSEEVIGPSSVKHASRPQNTFTETDHPNLDLKNRQKLSQMLNRLE
                     NEEKSVFPELDYFGQMHGTYLFAQGKDGLFIIDQHAAQERVKYEYYRDKIGEVDSSLQ
                     QLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEEEIASGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            26821..28041
                     /locus_tag="VB649_001156"
     CDS             26821..28041
                     /locus_tag="VB649_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP1670112.1"
                     /translation="MQEFLNLPKQIQLRQLVRFVTITLGSSIFPFMAMYYTTYFGTFW
                     TGLLMMITSLMGFVGTLYGGHLSDALGRKKVIMIGSVGTTLGWFLTILANLPNAAIPW
                     LTFAGILLVEIASSFYGPAYEAMLIDLTDESNRRFVYTINYWFINIAVMFGAGLSGLF
                     YDHHFLALLVALLLVNVLCFGVAYYYFDETRPETHAFDHGKGLLDSFRNYRQVFQDRA
                     FVLFTLGAIFSGSIWMQMDNYVPVHLKLYFQPTAVLGFQVTSSKMLSLMVLTNTLLIV
                     LFMTVVNKLTEKWKLLPQLVVGSLLFTLGMLLAFTFTQFYAIWLSVVLLTFGEMINVP
                     ASQVLRADMMDHSQIGSYTGFVSMAQPLGAILASLLVSVSHFTGPLGVQCLFVVIALL
                     GIYFTVVSAKMKKV"
     gene            28043..28639
                     /gene="ruvA"
                     /locus_tag="VB649_001157"
     CDS             28043..28639
                     /gene="ruvA"
                     /locus_tag="VB649_001157"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEP1670113.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLV
                     TIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAID
                     NSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG"
     gene            28649..29209
                     /locus_tag="VB649_001158"
     CDS             28649..29209
                     /locus_tag="VB649_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEP1670114.1"
                     /translation="MKRCSWVPKDNQLYCDYHDLEWGQPLHDDRDFFELLCLESYQSG
                     LSWLTVLKKRQAFRTVFHHYDIASVAAFTSEEMADALENLSIIRHKLKLAATVNNAIA
                     VQKIQKEFGSFSTYLWNFVGGKPINNLVNQENLVPAQTELSIRLAKDLKKRGFKFLGP
                     TTVYSFMQASGLVNDHEEACVFNRIF"
     gene            29278..30549
                     /locus_tag="VB649_001159"
     CDS             29278..30549
                     /locus_tag="VB649_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEP1670115.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFMSEKMAELGIDVYFQTAVGD
                     NEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDF
                     FAKRKPSSRTPNNERQAQVIEGSISLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
                     VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTL
                     RLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKY
                     DKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKMLGLPLEELKSHGVV
                     SAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLI
                     SGRSRLDVRYIATLHAFNMVRKTLLKLENLL"
     gene            30638..31774
                     /gene="recA"
                     /locus_tag="VB649_001160"
     CDS             30638..31774
                     /gene="recA"
                     /locus_tag="VB649_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEP1670116.1"
                     /translation="MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPQLFD
                     EIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED"
BASE COUNT         9952 a         5521 c         6538 g         9962 t
ORIGIN      
        1 tataaaaaaa taatatatat atcaaaaatc actaactagg agtaataagt tgaccaaaaa
       61 gctaggattg gttatgatga agataagatt aacagaaaga gaaattaggg aaggctatga
      121 aggacttatt aaaacagtat caggcaaaac cactaggaga ggagaagcgg tacgccgtat
      181 ttttacctct tattcttgtc aatgatgact ggcatgtctt atatgaagtc agaagtcagc
      241 atatttcaca accgggggaa gtttctttcc cagggggaca agtagaaaat caggagacac
      301 ttcaagaagc tgctatccga gaaacagttg aggaattgac tgttgatgcg tcccagatcc
      361 agctatgggg tgaaattgat tatttagtac agtcttctag aactattcat tgtttcgttg
      421 gtcaattagt cgttgatgac tgggaaagca tacagcctaa cgaagaagtt gacaaggtct
      481 ttacagtacc tttacgtcag ctacttgtca ctgatcctgt ctattatcat ttagaagcca
      541 ctcctattga gacaacggat tttccttttg accgtattcg taatgggaaa tgctaccaat
      601 ttagtcaaga gtaccgtagt attccgtttt atgaaaatct agaagaaacc atatggggaa
      661 tgactgccca gtttactaag tgtttaaccg atattctaaa tgatgaatca attgcaaaga
      721 aaaacccctt agatattgaa aaatctaagg ggagatagag cactagttta ttggcgtcaa
      781 ctttttgtca acaacctgta aaggttattt gtatttttct tctaattgac tcatccaaag
      841 tccgagccaa ataccaagag caaataacac aacggccata agccaggtta agatacctgc
      901 atgactgtag gaaatggatt cgggactact actatttgga ataagaatta atagcgtgct
      961 ggataataca ataccaatga taaagtggta aacttttgaa tgatggtgct gtaaagcata
     1021 atccatactt ttagaaaaag ccaagatggc taggactcct ccgatagcaa taggtaagaa
     1081 agtccctaat aaatccaaag atttgaatcc tattaacata ggaccataga gtcctaagat
     1141 aagtaagaga tttgacgggc ttagtccagg gaccagtact cctaaagcaa ttaaggcacc
     1201 tgctaaaata aaggttaaaa agttagctgg taaggtaccg attaagtcat ttaagaagta
     1261 aagacctagt cctgaaataa caaaggtaag gactagccat agccagtcaa ctttgtctct
     1321 ttgagactgc ttggttgact ccttaatcag actaggaata gtgccgacaa tagcgccagc
     1381 aaatccccat aagacgataa cttgatagtg cttaagcaaa aactcaacgg ggaaagaaaa
     1441 gagagcaata cctaaaatac caccaattcc tactggtaag aaaaataaga cattttcaat
     1501 aaagttatcc ctcatatgag ctaaaaagga aatcattcgc tcatagattc ctaaaatggc
     1561 tgcgagaaca ccaccggata caccaggtaa aataaaacct agtgcaataa tcatgccttt
     1621 aaaaactctt gaaataaatg aaaccattgt tgcctcctga aaagaatgat tttattgtat
     1681 cataaattta aagaattgct gacacaaagc tgcatatccc tactaaaata attgttccta
     1741 ataaataata cattataaat aatacattca attttgaaga tattttcctt aaacaccatg
     1801 tctttgtgat caagtcaagt ttgattgtca aagttgtaaa taaattttac aaagactgta
     1861 aaccttacga taattatcaa aaagataaac gaaaaaaagc ttaggtcaaa gacttttgat
     1921 agtaaactta ttgaagaagg attatagtag ctattaaaaa ggagatttat tatgggcttt
     1981 aaaaaccagt taccttatta ttgaaaaaaa ttacagatgt cacaagaaga gcttgctgaa
     2041 atgatgtatg tttcaagaag actatctcaa actgggaaaa cggtaaaagc tatccagacc
     2101 tgcaaaatct tttgatgtta agtaagtcct tacaggttcc tttagagcaa ctaatagcag
     2161 aagatatccc aaaaatgact ttaattatta aggatgagga gattaaacaa tgtgatagga
     2221 atacgcatat tatgttattt gggacactcc taattgctat cagtatttat cctataatgt
     2281 cttggttagg ttggtgggga tatggtccgg ttgctatctt atggttgata atcatgcgta
     2341 gcgccttaag aattgagcga tttaaaaaga catatgatgt tcagacttac cgataacttg
     2401 aagctatagc aaagggtgag agcttagatc agattgataa gattaaagaa aaagcaaaat
     2461 atccttatca aaaagcatgg attgttattg cgtacacagg attgacagtg ttaataaccc
     2521 tactctctat tttgtttttt catttgtttt tttaaacacg aaaaaagcct ttgaaacgtt
     2581 catttcatag gcttttctca tctcaattat tttacttctg taaaggttaa gtattttcta
     2641 ttttagctgt tataaacctt attgtatcaa tatttattga tagttgctta ataaaaggta
     2701 gagtgaatgg tagagtagtt attgcgttag ttcagcaatc ttttcaagat aaataaatac
     2761 ccacagcttc taactttcgt tgtcgtagta accccaatag gtcatgatag ataagaatat
     2821 aaaaaagggg ctgtctggct tttgcttaac gcaagccaca gccccaagga attaacgctt
     2881 ttgaccaata aaccacaatt ggttacgaac tcgaacagga gaagagaaat aatagtctgt
     2941 gtgttggatg acaatctctt ctttcagttg tactcccgta tcctttagga ttttttgccc
     3001 ctgttggtct ctaggaactt ttagaaatac agtaatggca tcttttcgta tatctacgat
     3061 acacttacgt acagctcggt taaacccgtt atggattgga ttgatagtgg taacggtctg
     3121 gtgttcaaag ttgcttacct tctgtactcg ttcacgctgg aaaaggaagt gtcttaatag
     3181 aaaggtgcga taaatagatt ggcagtagtt cccaaggcta tctgtattca agcgttgtat
     3241 catctttaat ccagataata aggctagaag taaagaaata agagcgaatc cataacatac
     3301 agaactaatg gtatcagtaa cgtttttaac cgtatccaga ttgacaaatg tgacggtaga
     3361 taattgaact gaaacaagat tgaacagcca accgaacaca tagcagattg gagcaataag
     3421 cagtaagtat aatatgagat tgaagcttct catgaagtag gttttagtgg tcataggata
     3481 cctcgcttag tatagtaggt tggacagagt aagggtagaa cttgatagga gtgttcatta
     3541 tcgacaactt gaatgatacc tgttccgtgt cctgttggaa tgacaatccc ctctggatct
     3601 aggtctggaa ataagaattg agtggttttc tgattgatat ttccaatttg caataatacg
     3661 tttagctgtt ccctcactga aatgggaata gtgttatggt caaaacgctg gcttcccaag
     3721 aatagatgga ttttagtagc atgtcccaac aaggcaattt gtgatagtag ggagaaaaaa
     3781 gcttctttga tattcttatt gactccctct gatagagcga ggacttcatc aataacaata
     3841 gttagatggg taaattgatg attgggatta tcatacaaga tagcttgtcg tttctgaatg
     3901 agagttgcac actggtttaa ttgttcattg acttgtgaaa cgaaatcaga ttttgaatgg
     3961 ttttctactg ggtggataac ggcaatttta ttttctcttg cccattggct aggggtatcg
     4021 aattttgggt caatgataat taggccggac ataggtttca ggacactcaa gaagtaagtg
     4081 agagcgtacg gtttcccaga acctgaattt ccagcaatag cccagtgact ccccttatct
     4141 aaattgagtt cgaagtgctt tatgacagga attttcccct gttgtaagct agatgaaaat
     4201 ttatctaaat caggaatcgc caagcgttct gaaatcccct ttctccaagg gaagaataat
     4261 ccacgttgaa tgtgtaagtc atccgtctct aaagggacaa aatctgtgca aattttgatt
     4321 tatctatttt ttgacttccg tttgacttaa tcgataaagt tgaccttgct tttttggaaa
     4381 taactaatgg gacggacgta aggtaagatt ttgggatatt ttctttatac attcgttcta
     4441 gaatatcatc aaccaggaat ccgatattaa atagtggatt ttctttgagt ttttttatta
     4501 ggttagggat aatttctgtc gaaacattat cataccacca tttattgatg aggggatcaa
     4561 tgttttcttg cctaaatgtt gagggtatgc catttccgtt taattcaaat aggataccac
     4621 agacattaac ttcaaatgat ttaattaaat tatcccctaa catcaaccaa ataatatcaa
     4681 acatttcttc aaaattaaag acagttaatt cattgatggt actggttcta aaacttctag
     4741 cgaggttata acttttttca ccaacagtca tgtcaatgtc atctttcttg tgaaaagtat
     4801 ccatttcagt ttcatcagaa gccaaaaaat tttttctttg aatattgaaa tttgcgaatg
     4861 tcttggaaag tctaagacag ctggattgta ttgaaattaa gtcatcgtcc gaaaaagaat
     4921 acattctttt atctacagtt tccaaatctc taaataaaat agagctgaag tagtggtaaa
     4981 acatattttc aacaaacttg gcaatatctc caaaaataat ttctttatag tccgagtcgg
     5041 tttgagtatt caaataaagc aatattgaag cggtaacttg tcgctttccc ttttcaactt
     5101 ggctaacttg acctgcatta cctaggtcac tttactttaa attatacttt tttcttaaac
     5161 atttgatacg agtaggtatt tcttgtgagt aattttcatc aaaaaatttc atagataagc
     5221 cccctacaaa catggaaaag tggtaaaaat agttgttatc ctagttgatt aaaaaaatct
     5281 ctgatttcct catcttttat aaaataatat ataattttcc cctctcttct agtgtccaag
     5341 atgttttgat tggctagttt acgaagatgg tgggaggcag atgccatact gagatttagt
     5401 aaacaggcta tatcgcagac acagagttct tcaacagtaa ggagataaaa gatgatattt
     5461 atctgtttat tatcggtaaa ctttgataaa atacgaagtg atttttggac ttttttcttt
     5521 tcaaggtagt tcgttgcggt tgtaacattt tgttgattta taacattcac ttggcagata
     5581 ctatcttttt tcataatatt ttctcctagc ctaacacagc ccatagcatg tcaaaactgt
     5641 tgttttcaat caggatatat atccccaatc ctaaataaac aacggcaata aaccatctgc
     5701 tatatttttc caaaatttct ccaacagaag ggacttgtgc caatttttgg gcagaaaaaa
     5761 ccaagagata aatcatgact agaaaggtaa gtaaagccac tatcaaattc gctaaattta
     5821 aggtagtaaa atacgggaca aagacaccaa tattgtcagc accacaactt gcaaaagtaa
     5881 tcatagcgac tagaaaaatc aggtttttat tatctttgcg caaaccttct ttggcaatag
     5941 cttctccatc agaatctcct aaaagcaaaa ctttgaggcc taggaaaatt ggaatcaaac
     6001 cgagcaaacc taaaatctct ttactaggaa tataatctaa gacaaatgca aaaagcaaac
     6061 ttagcaatat tagactaaca gagcctagaa attgtcctaa atagatgtta atgatgtctt
     6121 ttctgctttt tcttttggca aaaaataaca ttaggataat aagtaagtct acggctgtcc
     6181 cagaatacag gattattgaa gtaacaacat tttgaatcat aaaacacctc attcaaatat
     6241 atttttgaat gaattttaac attaaacttt gtagatgtca atttcagctc caccaaaata
     6301 tagataagaa gttagtgtac caaatataaa aaagccctgc catccaaatg ataacagggc
     6361 ttaacttcaa tatccaaatg atatattcat ctaaaaaagg tagagttttt attgatttat
     6421 attacaatgt aatgaacttc aaaaattcaa aaatcgctta aaatcaacgt tttgacgtct
     6481 aatgacgtgt agtgaacccc ttacttaacc tctgtaaatg taacgtgttt acgtaatttt
     6541 ggtgagtatt ttttcaattg aagacggtct ggagtgttac gtttgttttt tgaagtaagg
     6601 tacaagcgtt caccagattc tttatgttca agtgtaatat ttacgcgcat ggtatctccc
     6661 ttctattatt tagcttcgtt agctttagcg attttacgtc ctttgtagta tcctttaagg
     6721 gatacacggt gagaacgtga gtaatctcca gtagtttcgt cgaattgtac agatggagct
     6781 gtcaatttgt agtgtgtacg acgtttgttt ttcttcgctt ttgacgtgtg acgtgcaggt
     6841 actgccattt tcttgttctt cctttcgatg tgtaagtttt gattttcatc aacttcacta
     6901 tgataacata tcttttttgt aaagtaaagt tacttgacaa aactttttat ttttacaatt
     6961 tcatggtgaa aatactatca aactaaagca aatgatatat gcttgtttaa aatataagaa
     7021 aaaatggtag aatgtttaaa gagaaaacta atcaaagagg taaacttatg aaacttcaaa
     7081 aaccaaaagg aacccaggat attcttcctg gggatgctgc gaaatggcag tatgtggaat
     7141 ctgttgcgcg tgatacgttt agccaatata attatggaga aattcgtact cctatgtttg
     7201 aacactacga ggtaatctcg cggtctgtag gtgatacgac tgatattgtg acgaaggaaa
     7261 tgtatgattt ctatgataaa ggagatcgtc acattacctt gcgaccagag ggtacagctc
     7321 cagtggtacg ttcttatgtt gaaaataaat tgtttgcgcc agaggtccaa aaacctgtca
     7381 aactttatta tatcggttcc atgttccgct acgaacgccc tcaagctggt cgtttacgtg
     7441 aatttcacca aattggagca gaatgtttcg gtgctgctaa tccagcaaca gatgttgaaa
     7501 ccattgcgat ggcctatcac ctctttgaaa aattgggcat taaggatgtc acccttcatt
     7561 taaatagttt ggggagtcct gagagtcgtt cagcttatcg tcaagccttg attgactact
     7621 taacaccaat gcgtgatcaa ttatctaaag atagtcaacg tcgcttggat gaaaacccac
     7681 tgcgcgtgct tgattctaag gaaaaagaag ataaactagc cgttgaaaag gcgccttcta
     7741 ttttggatta cttagatgag gaaagtcagg cgcactttga ggcagtcaaa gctatgcttg
     7801 aagcacttga cattccttat gtgattgaca ccaatatggt gcgtggcctt gattactata
     7861 accacactat ttttgaattc atcacgtctg tggagggttc tgacttaact atctgtgcgg
     7921 gtggacgtta tgatagtttg gtaggttatt ttggtggacc agaaacccct ggctttggct
     7981 ttggtcttgg tttagaacgt ctcttgatga ttattgaaaa gcagggtctt gccttaccaa
     8041 ttgagacaga gatggatgtt taccttgctg tgctaggtga tggtgctaat agcaaagctt
     8101 tagaattggt tcaagccatt cgccgtcaag ggtttacagc tgaacgagat taccttggcc
     8161 gtaagattaa ggctcagttt aaatcagccg atacctttaa agcaaaattg gtaatgactt
     8221 taggagaaag tgaagttgaa gcaggcaaag ctgtgattaa gaataatcgt agtcgtcaag
     8281 aagtggaagt cagttttgaa gatatgatga caaactttgc gaacatctca gagcaattat
     8341 tatcttaatg attttattgt cgtcataagc ttgtgttgat atgattgttt agaagataat
     8401 cactaaaaca ggtgtaactt ctctttttag aagggagttg cacctgtttg ttttctgtaa
     8461 ggggattgat tagctttctt agtattctgt gaggacacct gatatgtcaa aatactgacg
     8521 gctcagtatt cttgctttat ctttagaaaa actcttttta aatgggtggg gtttttaagg
     8581 gctttttgct ataatagtag ggaatgaatt aattgattta tatagtgaaa ggaattggaa
     8641 acgagcaggt ttcacaggat tctgtttgtt ttagggaatt tatttatgaa acgtagcatg
     8701 tatgcagggc gtgttcgcga agaacacatt ggaacgacaa tcacattgaa aggatgggtc
     8761 agtcgtcgtc gtgacttggg tggtctcatc tttattgatt tgcgtgaccg tgagggtgtg
     8821 atgcaattag tcattaaccc tgaggaagtt tccagtgatg tgatggcaac tgctgaacgc
     8881 ttacgtagtg aatatgtgat tgaagtggaa ggttttgttg aagctcgaca acaagccaat
     8941 gataagttgg cgacaggaat ggttgagtta aaagtatctg ctttgaccat tttaaacaca
     9001 gctaaaacga cgccttttga aattaaagat gacgttgaag taagtgacga cacgcgttta
     9061 cgttaccgtt acttagattt acgacgtcca gaaatgttag aaaacttcaa gctacgtgca
     9121 aaagtgactc attctatccg taattacctt gatgatcttg agtttatcga tgtcgagaca
     9181 cctatgttga caaaatcaac tccagaaggt gcgcgtgact atctggtacc aagtcgtgtt
     9241 agccaagggc atttctatgc tttgccacaa agtccgcaaa taaccaaaca gttattgatg
     9301 aatgctggct ttgatcgcta ttatcaaatt gtgaaatgtt tccgcgatga agatctacgt
     9361 ggtgaccgtc aacctgagtt tacacaagtt gacttggaaa cgtcattcct ttctgaacaa
     9421 gaaattcaag acatcgttga aggcatgatt gctaaagtga tgaaagagac aaaagaaata
     9481 gatgtaaccc taccattccc acgtatgagc tacgatgtag caatgaatag ctacggctct
     9541 gataaaccag acacacgttt taaaatgctt ttacaagact tgacagtaac tgtcaaagga
     9601 attgacttca aggttttctc agaagcacca gctgtcaagg cgattgtggt gaagggaaat
     9661 gcagatcgat actctcgtaa agatattgac aaattaactg agtttgccaa acaatttggt
     9721 gctaaaggcc ttgcctgggt taaggtgaca gatggtcaat tggcaggccc agtagccaag
     9781 ttcttgacag ctattgagac agagttgtca agccaattaa aacttgctga gaatgattta
     9841 gttttatttg tagcggatac tcttgaggtt gctaataata cattaggtgc ccttcgtaat
     9901 cgtattgcca aggaccttga catgattgat cagtcgcagt ttaatttcct ttgggtggtt
     9961 gattggccaa tgtttgagtg gtcagaagaa gaaggacgtt atatgtcagc tcatcaccca
    10021 ttcactcttc caacgccaga atctgctcat gagttagagg gtgatttggc taaggtacgg
    10081 gctattgctt acgacatcgt tttaaatggt tacgagcttg gtggtggtag cctgcgtatc
    10141 aatcaaaaag agatgcaaga gcgcatgttc aaggctcttg gctttaccgc tgatgaagct
    10201 aacgcccaat ttggtttctt actagaagcg atggactacg gctttcctcc tcatggtggc
    10261 ttggcaattg gtcttgaccg ttttgtcatg ttgcttgctg gaaaagacaa tattcgagaa
    10321 gttattgcct tccctaaaaa taacaaagcc tctgatccaa tgacgcaagc acctagtctt
    10381 gtttctgaaa accaattaga agaactcagt cttcaaatag aaagtcatga ttaagaaaac
    10441 aacctataag aaaaaagtta aatatgtcat tagtagaggg gccaagaaag ttggcctact
    10501 ccacgctcta agaagtattt caagagaaaa atatgcagag aagatttcgg cttctctgct
    10561 ttatggcatt ctctctagta ttgctgtgaa ttttttcttc cagcctgggc atgtttattc
    10621 aagtggagca actggtctag cacaggtttt ttcagctctt agtcatcgtc ttttaggcta
    10681 tgattttccc atcgcctttg cgttttattt gattaatatt cctttgctta ttttagcttg
    10741 gtataaaatt gggcatcaat ttaccatttt tacctttatc acagtcagca tgagttcttt
    10801 ctttattcaa atcatacctc aagtgacgct gacgactgat cctcttatca atgctatttt
    10861 tggtggtttg gttatgggaa tgggaattgg tacaggtctc aaatcacgta tctctagtgg
    10921 ggggactgat attgtcagtt tgacccttag aaaacgaaca ggcaaggatg tgggcagtct
    10981 ctcattgatg gttaatggtg caattttagc ctttgcaggg attttatttg gctggcagta
    11041 cgccctttat tctatggtct ctatctttgt atcaagtcgt gttacggatg ccattttcac
    11101 caagcaaaag aaaatgcagg caactattgt taccagccat ccagagcgtg tgattcatat
    11161 gatccataaa cgtctgcatc gcggggtgac cagtatcaac gacgcagaag ggacttacaa
    11221 gcatgaacaa aaagcagttt tgattaccat tttgacatgt gaagaatacc cagaattcaa
    11281 atggctgatg ttaaaaacag acccacaagc ctttgtttca gtggctgaga atgttagaat
    11341 tatcggtcgt tttgtggaag atgattaaga aaaacacagg aggtgtcatg tcaattgacc
    11401 aacgtttaca gttaaagaaa ttttgcttta ttattttagg agctgctatc tacgcctttg
    11461 cttttgttta tttttacatg gctaatcgca ttgcagccaa tggtttagct ggtctcaccc
    11521 tagttggtaa ggcacttttt gagattgatc cttctttgat aggctatttg attaatttgc
    11581 ctttggtctt gctgggagct agatgttttg ggaaaagagt catggtttac acagtaacgg
    11641 gtgttttatc actttacttt tttgtgtggc tgtttcaacg ctttcctttg gtcgttgact
    11701 tggaccatga caatttagtc gtttccttga tggctggaat tattggtggt ctaggtggcg
    11761 gtcttgtgtt tcgcaatggt ggaaccatcg gtggagcaga tattattgct aagttattag
    11821 aagacaagtt aggactacag ctgaatcaag ctcttttagg cattgatctt tttgtcatga
    11881 ttgtctcttt gacttatatt tccctgccgc aaatgatgta tgctctgatt gctagcttta
    11941 tgtatggtca aattgttcgc ttggtacaac aaggtggtta ttcagcccgt ggcattttta
    12001 tcgtttcaga acaagcggag aaaattgccc ggttcatcat ggaagaattg ggaaggggag
    12061 ttacttatct aacaggtgaa ggagcctact ctggtcgccg taaaaaagtg atttatgtgg
    12121 ctttggggcg aagagatatt agggaattaa aagctttttt aactcaggtt gatcccaatg
    12181 cctttatcac ttattttgat gttaatgaag tcaatagccc agaattttta actattaaaa
    12241 gcaaatacca taaaaagaga aaataaatga gcattagagt tgcctgcgaa gaatagtgag
    12301 gatgaaggat ggcacatcac gataaattga ctaaactact aaaactgttt ttgattgccc
    12361 taggtgtagc catttatacc ttcggttttg ttaattttaa catggctaat gctttggctg
    12421 aaggtggtgt ggcaggaata accttgattt tacacgcgca ttttgggatt aatcctgctt
    12481 actcttctct cttatttaat cttccacttt ttattttagg ggcaaagatt tttgggaagc
    12541 gttctttggc tctaaccatc tatggaacag ttctgatgtc cgcttttatc tggatgtggc
    12601 aaaaagttcc tatcgaactt ggcttggaaa atgacatgat gttggtggct gtagtggcag
    12661 gtctcttttc agggattggg agtggcattg tttttcgcta tggtgcaacc acaggcggaa
    12721 cggatattat tggtcgcatt gcagaagaaa aatttggagc taagctaggt caaactttgc
    12781 ttttggtgga tgctcttgta ttgacagctt cgttgactta tgtggattta aaacacatgc
    12841 tttatacttt ggtggcaagc tttgttttta gccaaatgat tagtgtggtt caaaatggtg
    12901 gttacactat ccgtggaatg attattatta ccaagcattc agaggctgcc gctcaagcta
    12961 tcctaaccga aatcaatcgt ggagtgactt acttgaaagg tcaaggagct tactctggta
    13021 atgattacaa tatcatgtat gtgaccttga acccaactga agttcgggaa gtcaaacgta
    13081 ttttagctgg tttggatcca gatgccttta tctccattat tgatgtggac gaagttatta
    13141 gctctgattt taaaattcgc cgaagaaatt atgataaata aaaatacagg tcaaacagcc
    13201 tgtattttta ttttggtccc ccacttaaga aactaccaag cataatagct gatatagcag
    13261 ttcccttgta atggctagct tttgttttta ccaagcgact aagatcaaat atgcttttag
    13321 gagcatcaaa ttgatgtgtt aagatgtatt gattgataag tgagtcaatt tttgtagcta
    13381 ggagtgagct catcccctct ttttcaagtt gactggcgag ctcgaagatc gcttgacgaa
    13441 aataatcatc ggcttgtatt acttgttcgc tataaacttt actaagagca tctaatattt
    13501 ctttttctga tggcatggca ttctcctgta acatattgtg ctattattat aatataaaaa
    13561 actaagactg tcataaatgt gacagcctta gtaatgttat tacttacatt tcatttggtg
    13621 cgtcaacacc gagtaagcga agcgcttctt taagaacagt agcagttgca tagcagagag
    13681 ctaagcggtt atcacgttct gagttgtcgt caagaatgcg agtgtgagca taatatttgt
    13741 taaagctttg ggctaagtta atagcaaatt tagccataat agaaggctca aagttatctg
    13801 atgttcgctt gataatgcgt gggaaatctt ggataagttt gataatttcc cagctttcag
    13861 catcagctaa actgtaagtg gtggttgcag atggcgtaaa gtcagcttta cgtagaatag
    13921 attggatacg agcatgagca tattgaacgt aaggtccagt ttctccttca aaggaaacca
    13981 tggcttcaag gtcaaagtca tacccattca tacgatctgt tttgagatcg taaaacttga
    14041 tggcaccgac accaacagcg tgtgcaacgg cttctttgtc agcaaggttt ggatttttcg
    14101 cttcaatttg agaagctgca cggttaatgg cttcagcaac cgtaggttca agaagaataa
    14161 cattaccttt acgtgttgat aatttagcac cgccttttgt gacaagtcca aaagcaacgt
    14221 gtgtcatatc atctgaccaa tcgtaaccca tttcttttag cactgctttt aattgtttga
    14281 agtgagcagc ttgctcatta ccaacaacat aaacggattt agcaaagtca taagtgcgct
    14341 tacggtaaag tgcggcagct aggtcacggg taatgtaaag agtagcgcca tctgattttt
    14401 tgatcaaggc agggtgttca atgccgtatt tttcaaggtt aacaacttgg gcacctttag
    14461 attctacaag aaggttttta gcttctaata agtcaagaat ctcatccatt ttgtcattat
    14521 agaaggcctc accgttgtaa ctatcgaagg tgacatgtaa ttggtcataa agtcggttga
    14581 actcaagtaa actttcatca cggaaccatt gccataattc agtagcttct ttgtcgccat
    14641 cttccaattt acggaaccat tcacgagctt cttcatcaac ggtgggatca gtttcagctt
    14701 cagcattgat acgaacgtaa agttttaaga gttcatcaat aggatgtgcc tgaacagcag
    14761 cttcatctcc ccattttttg taggcaacaa tgagcatacc aaattgttta ccccagtcac
    14821 caaggtgatt gatttttaca ggtttatagc ccattttggc aaaaatgtga gcgagactat
    14881 caccaataac tgttgagcgg aggtgaccga ttgaaaatgg cttagcgatg tttgggcttg
    14941 acatgtcaat agcaacattt cgcccttgac cttcgtcttg ctgagcatag tctgaacctg
    15001 ctgtaatcac ttgttcaagg acctgtgagg aaatcttagc tttatcaagg aaaaagttga
    15061 tgtaagggcc gacagctacg actttttcaa attggctctc atcaatctgt tcagctaact
    15121 cgctagcaat catttgaggg gctttgcgaa ggacttttgc taagctaaaa gctggaaagg
    15181 caaggtctcc catgtcagaa ttttttgggg tttcaagcaa gttaaaaata gcatcttgtt
    15241 ctaattctgg aacaacttta gctatttcac ttgcgattag agttttagta tccatacagc
    15301 gtctcctaaa aattgtttgt caccctattc taacatattt ctttaaaata aacgaggaga
    15361 ggattgataa attatactga aactttcaag gaaatgaatt gcttgaggtt gttgtttttc
    15421 tgaaaatgtt ataaaaagag aaatgaggtt tcttttcaac agttttcaag tgaaattcca
    15481 gttgaatttg ataaaaaatt gctgaaaata gctgggcgaa gatgaaataa tacacttttt
    15541 ttgttataat ttgagaggat aattatacaa ttggggtgat atatcatgaa taaaatggag
    15601 cgtcaacagc agattaagcg aatcattcaa gcagagcata ttggcacaca agaagatatt
    15661 aaaaatcacc ttcaaaaaga aggcattgtg gtcacccaag caactctatc tcgggactta
    15721 agagaaattg gccttttgaa attgagagat gaacaaggca aactctatta tagtttgtct
    15781 gaacccgttg caacaccatt tagtcctgag gtgcgttttt atgttttgaa agttgatcga
    15841 gcaggtttta tgctggttct ccataccaat ttaggagagg ctgatgttct agctaatttg
    15901 attgacaatg atgccattga agatattcta ggaaccattg ctggtgcgga taccttgctt
    15961 gtgatttgca gagacgaaga gattgctaaa cgctttgaaa aagatttggc tgcaggccta
    16021 tgactagcta tcaagagtct ttgacacaat tgattcttgc tatccatgaa ttctagtatc
    16081 gttgcttata aagaagtgaa gcaatagctg tctaagctcc gtgattttaa aaagtaagct
    16141 tatcagatga aacgctatca acaagatgcc ctgcttttca aaaaaaatag ataaagaaaa
    16201 ggctgcgaca gtatctgcaa gcagggcaaa agaactagaa gataggctca gtcatcagcc
    16261 attaattgat gattatcgag aaaagatgca agatgcaagt gatgtgattc agtatatcac
    16321 caaacgtata gaagatcagt taaacaagga gttaataaat ggcaaaaact aacatttctc
    16381 ctggaatgca acagtatctg gacatcaaaa aagattatcc agatgctttt ttgcttttta
    16441 ggatgggtga cttttatgaa ttattttatg atgatgctgt caaagcagca caactcttag
    16501 aaattggttt gaccagtcgc aacaagaatg cggaaaatcc aattcccatg gcaggcgtgc
    16561 cacatcattc tgcccaacaa tacattgatg tgttaattga gttgggttac aaggttgctg
    16621 tcgcagaaca aatggaagac ccaaagcaag ctgttggggt ggtgaagcgt gaggtcgttc
    16681 aagtcataac tcctggaacg gttgtggatt cagctaagcc agatagcgcc aataactttt
    16741 tggtagctgt tgactttgat ggttgccgtt atggattggc ttatatggat gtgtccacag
    16801 gtgaattttg cgtgacagat ttggcggact ttacgagtgt tcgtagcgaa atccaaaacc
    16861 tcaaggcaaa agaagtctta ctaggttttg atttatctga agaagaacag acgattttgg
    16921 tcaagcagat gaatttgctg ctttcttatg aagaaacggt ctatgaagat aaatctttaa
    16981 ttgacggcca attgacaacg gtagaactca cagcggcagg aaaactcttg caatacgttc
    17041 acaaaacaca aatgcgagaa ctcagccact tgcaagcctt ggttcactat gagatcaagg
    17101 attatttgca gatgtcgtat gccactaagt caagtttaga tttggtagaa aatgctagga
    17161 ctaataaaaa acatggaagt ctgtattggc ttttagatga aaccaagaca gctatgggga
    17221 tgaggctttt gcgctcatgg attgatcgac ctttggtttc taaagaagct attttagagc
    17281 gtcaagaaat tattcaagtt tttctgaatg cttttattga gcgaaccgat ttaagcaata
    17341 gtttaaaagg tgtttacgac atcgaacgct tatctagtcg cgtgtctttt ggcaaggcaa
    17401 atccgaaaga tttacttcaa ttgaggcata ccttagccca agtgccttat atcaaagcta
    17461 tcttagagtc ttttgacagt ccttgtgttg acaaacttgt caatgatatt gacagtttgc
    17521 ctgagttgga atacttgatt agaacagcca ttgatccaga tgcaccagca actattagtg
    17581 aaggaagtat tatccgcaat ggttttgatg agcgcttgga ccattatcgt aaagtaatgc
    17641 gagaggggac aggctggatt gcggatattg aggccaaaga gcgtcaagaa agtggcatta
    17701 ataacctaaa aattgattac aataaaaaag atggttatta ttttcacgtt acgaattcaa
    17761 atcttagctt agttcccgag cattttttca gaaaggcaac tttaaaaaat tctgagcgtt
    17821 atggaacagc agaattggct aagattgaag gtcagatgtt agaggctagg gaagagtcat
    17881 ctagtttaga atacgatatt tttatgtgta ttcgagctca agttgaaacc tatattaatc
    17941 gtttacagaa actggctaaa actttggcaa cggtggatgt tttgcaaagt ttagcagtcg
    18001 ttgctgagac caatcattat atccgaccgc agttcaatga taatcatgtg attacaattc
    18061 aagaaggtcg tcacgcggtt gttgaaaagg tcatgggggt gcaggaatac attcccaata
    18121 gtatctcttt tgaccaacag accagtattc agctgattac aggtccaaat atgagtggta
    18181 agtcgactta tatgagacag ctggccttaa cggttatcat ggcccagatg ggttcatttg
    18241 tggctgctga ccatgttgat ttacctttat ttgatgcgat ttttacgcgt attggggctg
    18301 ctgatgattt gatttctggg caatcaacct ttatggtgga gatgatggaa gcaaaccaag
    18361 caatcaaacg cgcaagtgac aactctctta ttctatttga tgaactggga cgaggtacgg
    18421 caacttatga tggtatggct ttagcccagg caattattga atatatccat gatagagttg
    18481 gtgctaagac catatttgca acgcattatc atgaattgac agacttgtca actaagttga
    18541 caagtctagt caatgttcat gtagcaacgc ttgaaaaaga tggcgatgtt accttccttc
    18601 ataagattgc tgagggaccg gcggataaat cttacggtat tcatgttgca aaagtagcag
    18661 gactgccaaa atccctatta aagagagcag acgaagttct gacccgttta gaaacacagt
    18721 cacgatctac tgagataatg tcagtccctc cacaagttga gtcaagcagc gctgttagac
    18781 aggggcaatt atcccttttt ggtgatgaag agaaagctca tgagattagg caagcactgg
    18841 aagctattga tgtcatgaat atgaccccgc ttcaagcaat gacaaccctt tacgaattga
    18901 aaaagttgtt atagtttttc agctgaaaat gaaaaagatg ctttctatat tgaaggcatc
    18961 tttttgttct gtcaaaaacg gtccgaggcc ttcggctatt tattaagtgt gttataatag
    19021 tccataagaa tgcgaggaaa ttatgacaaa cattattgga cttggtttag cagcctttac
    19081 agggcattga cagtccttaa gtattgatat aactgtgttt ttgaaaaaat ataggtttta
    19141 agtttcctta gagtttcctc aaaagtccac aaaaaggtga acaaaaaaaa agacctttac
    19201 aggtccttta cacaatgagt tcagcaggca agaactagcg tagtttaaat actacgcttt
    19261 tagtttgccc tatggcttat tatagcacga ttagtgtcat tgaggaaaaa actaccctct
    19321 caaccagcct ttaaagttcc accactggtc ttggatgcta tcgctcaagc gttgatgcca
    19381 agtttttttg gcttcttctt cgatagaacg cttgaataac tcctccgcat attgttgctc
    19441 ttcggcttcc ctttcttttt gaaggcgttc attttgcgtt ttttcatcct caaatacgag
    19501 ttgcccgaag tatagatttc caccatccgc aaaagatagg gtaactttgt ctccttcaac
    19561 aagtggtttc tttaatttaa cagtataatt tccatcttct ccagcgcgat aaccactggt
    19621 ttcccattct ctttcatagc agtctggaga ataaatccat gttttagttt tatcgcatgt
    19681 aactttatgt ttaatattag ggacttctat ttttttatcg ttgacagatg caaaaacata
    19741 accaaaagaa cctacgtgaa cactaatctg ttgatcgcca acgttaaagg gcgaaacagt
    19801 tacctcagat aaatatcctt gagttgtaaa ctgagtgttt acggccgtcc cctccgcttt
    19861 aacactcaca gcacacattg atagacagaa ggctgctatc ataactaatt tctttttcac
    19921 catattctcc ttaaaattaa atatcgaact ccatagtacc agttaatcgg taaaaaaatc
    19981 cattctattt tttgacattt tatgtctaat ttgacctgct aagtcagctt tgcaaacgat
    20041 accaagtgat tttcttctaa tcgttatttt ttagatggat atgttaactt tgttagagat
    20101 gtattaatct taatagactg tttctattcg ggaggtttct tcctttctcc caattattaa
    20161 cagtactttt ataagtgcca aagcgttttc caaattcctc catagtttcg cctaagttaa
    20221 ggcgaatagt tttgattttg tcacccactg tcatagcttg cctgcctttt taatcaatga
    20281 agtactatta ttttcgtact tttttaccta aaaaaaggtt atcaatagtg acaccgtaca
    20341 aagatgataa tttttgcaat agtcctaaag aaatatcgga gctatctttt tcgtactttg
    20401 aaatagtttg gggatttttc ccaactgctc cagctacttg ttttaaagtg taaccagcgt
    20461 tgattcgggc agcttttagt gtaatttgcg tcatgttttc aactcctttc taaaaagcta
    20521 tggcttaata gtactattat tttcgtgcca agtcaatgat ttttgtagaa aaatattaaa
    20581 aaaatagtac ttttaggttt atttgtgtta gaattaattc agatacaaaa agaaaggggt
    20641 aagagaaatg gctaaaaata gtccccaaga tttaataaat agagaaattt tctcaacaaa
    20701 tctcaacatg cttatggcta aaaagaatat caaacagata gatattcaca acaaactagg
    20761 aatacctaag agtacgataa ctggctatgt taaaggtcgt tcactcccaa ctgctggaaa
    20821 cgttcaaaag ctggcggact tcttcggagt tctaaaatca gacattgacc cccgttttga
    20881 ttctaataat attgaaacaa atagtaatat tatcccatca accctacaaa aagtaacatc
    20941 tactttatct cagctagaac acaagcgaca attaaacgtc cttgattatg ctgaaacaca
    21001 attagaacaa caaaacacag tagaagaacc acaagccacc tactacactt acaattacta
    21061 cgaccacgca gcttcagctg gtacaggtca gtatctaaat gatgtacaag tagaaacaat
    21121 tgaattacca gtcgattatg acgctgattt tgtcataccg gtctatggcg attctatgga
    21181 acccgaatac cattctgggg actatgtatt tatcaaacta tctattaacc tgtcagatgg
    21241 tgatatagga gtttttgagt attacggtga tgcttatatc aaacaacttg ttataaacga
    21301 ttctggagca tttctgcata gtctgaacga caagtatgac gatatactca tagatagaga
    21361 tagtgatttc cgtattatcg gagaagttat tgggagtttt acatctaaat catgactatc
    21421 tgatacccac gcgccgaatt ccactatttt ccactaattt tggttgcttt acctttaagg
    21481 actcgcattt tgctctttaa gacagccgaa aagtccgatt ttctgaatac tatatgctaa
    21541 aaatgccaac tgattttaga agctgtcaca acggaaaaag taaattaata aacgaccgat
    21601 atatcaagtt ttttcaagtt ctttaagtga atttaccgag cgttttacaa ctattgaaat
    21661 aggttgacgt attatgtcag tatgtgccaa cattttccag cattccgaaa tgcgaccatg
    21721 tgttcgtgtt tgggagtaat aaccttctat tctctaagtt cgctcgaagt tcagcattat
    21781 gcgcgtggaa caaatttagc taccttacag ttaccgctca ttttatgacc tgttaaattt
    21841 ccgtgtataa atgccaactt taccatctct gtacacacgc aaactccttg atacgccttt
    21901 gattttcttt aattacaaga ccctcaaaac ttagcaaaaa ttgaggtata atcggaactt
    21961 ttcggaactt tttgtcggcg gcaattaaaa actgtctgtt ttctctttgt tcagcattat
    22021 gcgcgtggtt gtatttcaat aaaaggagat tttctatgag tataaacaaa aagcaagtat
    22081 ttttgacact gtgtggtatt tctatttcag tgacaggtat tgatatgctt ctatctggtg
    22141 agtatctaag aggagttatc aagtagattt tagcttttgg aatttttgtc atatttagca
    22201 aagatagaga tgaatagccc atagtttcta ttttaagttc gaaaatgccc actataatgt
    22261 gttaaaacag acatgaaata ctctagcagt gtaaaactat actccactgc tttaagtcta
    22321 aaaatgagct accagagtag aaaaaacgac ttataactaa aactattatc ttatctgtta
    22381 agcagttgca taaaatatca taaaaatata cataaaatta tttttattca tttttaactc
    22441 accgtacctt gaccgttaga ccatagaaag gaaaagcatg aacggattac aacattatga
    22501 cgaattagct ttcgaaaata ttaaacacat agatgaaaac ggtgtagagt tttggtatgc
    22561 ccgtgaatta caaactgttt tagagtatgc taaatgggac aattttttaa acgttattga
    22621 gcgggctaaa atagcttgtg aaaacactgg aaaccccgtc gctatgaatt ttcccgaggt
    22681 cagcaaaatt gtacagctcc ctctaggaga tagggagatt aaagattata aactatctcg
    22741 ctatgcctgc tatttgattg tccaaaatgg tgaccctaga aaagaagtca ttgcactggg
    22801 tcaatcatat tttgctatta aaacccgtca gcaagaacta gctgataatt tcaacaaact
    22861 cgatgaagag cacaaacgtt tagcgattcg ccaagagatg aaggaacata ataaatcatt
    22921 agctgaagct gctaaaatgt cgggtgtcac taactacggc aagtttcaaa actttggata
    22981 taaaggcctt tatggtggaa tgtctatgca agatattcat gatagaaaag aactagaaaa
    23041 agggcaaagt attcttgatt atatgggtag tgctgaattg gccgctaact tattccgtgc
    23101 tactcaaacc gatgaagtgt taagaaatcg gcagatacac gatgaaaatc tagctaacga
    23161 tacacacttt aacgtaggta gaacaatcag aaaaacaatg cagaaactag gcacaactat
    23221 gcccgaaaat ctccctacac ctcaagagag tatccaagat ttgaaaaaga aacataaaca
    23281 actagataaa caaccagacg ataatcaact ttcacttttt gatgatatgt aaaaaatagg
    23341 caataatatc ctcgtatagc tatttcaact ctcaatcata taattttatc aacttacccc
    23401 ccaaaaaaaa caaaaaagac cccgcaagtt ttccacgctc gcaaggtctt aaaaagccta
    23461 atattatacc atgattttct tttataatat ttcggatatt tacccgatac cattattata
    23521 ccatgatatg aactaatcta aaaccctttt aataatagct tgcctgctga tggaaaggtt
    23581 tataatcatg aaaataacag aacataagaa gaaaaacggt acaatcgttt atcgtgctag
    23641 tatttatcta ggcattgacc aaatgacagg taagagagta aaaacaagca tcacaggaag
    23701 aacaagaaaa gaagttaatc aaaaagccaa gcacgcgcag cttgacttcc tatctaatgg
    23761 atctacaatt aaaagaaaag ttgtgattaa aacatttaaa gaacttagtc atttatggct
    23821 tgaaacctat aagttaacag taaagcctca aacttatgat gctactgtta ctagacttaa
    23881 tcgacatatt atgccaactc tgggcaatat gaaggttgat aagataaccg ctagtgatat
    23941 tcaaatgctg attaatagat tatctaaata ttacgtcaat tatactgcgg tacgttcagt
    24001 catccgaaaa gttctccaac aaggagtatt gctagggcta atagattata actcagcaag
    24061 agatattatc cttccaagga agcagccaaa cgctaagaaa aaagttaagt ttattgatcc
    24121 gtctgatttg aaatcttttt tagaacattt agaaactagt caacacaaac gctataacct
    24181 ttactttgat gcagttctct accaactttt attatccact ggcttgagga taggcgaagc
    24241 ctgtgcatta gagtggggag atattgacct agaaaatggt acaatagcca ttaataagac
    24301 ttacaataaa aatttgaagt ttttgagtac agctaaaacc cagtcaggca atagagtgat
    24361 tagtgttgat aaaaagaccc ttagaagcct aaagctctat caaatgagac agcgacaatt
    24421 atttaatgag gttggtgcgc gtgtgtcgga ggtagtgttt gccacaccaa tacgaaagta
    24481 ttttaatgct tcggttagac aaagcgcttt agatactagg tgtaaggaag cagggattga
    24541 acgctttacc tttcacgctt ttagacacac tcacgctagt ttattgctga acgctggtat
    24601 tagttataag gaacttcagt accgtctagg acatgcgaat atcagcatga ctttggatac
    24661 ctatggccat ctttctaagg acaaagaaaa agaagctgtt ttatattatg aaaaggctat
    24721 gaataacttg tgagtccaca aaaaagtcca caaattaata ttttgagagg tgtaaaccta
    24781 atgaaacctt gttatatcaa cgtttagaaa gtgttaaaaa caaaattatg acaaaaatta
    24841 ttgaattacc ggaagttctc gccaaccaaa ttgcagctgg tgaagttgta gaaaggccag
    24901 cgagtgttgt caaggaattg gttgagaatg ctattgatgc taaaagtagc cagattaccg
    24961 ttgaaattga agagtctggt cttaagatga tacaggttac agacaacggt gagggaatgt
    25021 ctcatgaaga tttaccttta agtctgcgtc gccacgctac tagtaaaatt aagagtcaga
    25081 gtgatttgtt tagaattaga acacttggct tccgtggaga ggctttaccg tctgttgcct
    25141 ctatcagtaa aatcacgata aaaacagcaa caaaagaagt cactcacggt tctcttctta
    25201 tagctactgg tggggaaatt gagacacttg aagcgatctc aactcctact ggaaccaaaa
    25261 ttaaggttga aaaccttttt tacaacacgc ctgctcgtct caaatatatg aaaagtttac
    25321 aggcagaatt agctcacatt gtagatgtgg tcaaccggtt gagtttggca catccagaag
    25381 ttgctttcac actgattagt gatggtcgcc aattaactca gacatcagga actggcgatt
    25441 tacgccaagc aattgcaggg atctatggtt tgaatactac caaaaaaatg ctggttatct
    25501 ctaatgctga tttggatttt gaagtttccg gctatgttag cttgccagag ttgacacgcg
    25561 ccaaccgtaa ttacatgacg attttggtta atgggcgtta catcaagaat ttcttgctta
    25621 atcgagcaat tcttgatggt tacggttcta agctcatggt tggacgtttc ccaattgttg
    25681 tgattgatat tcagattgat ccctatttgg ccgatgtcaa tgttcacccc acaaaacaag
    25741 aggttcgtat ttcaaaagag cgtgaattaa tggctttaat tagcacggct atttcagaga
    25801 gtcttaagga acaagatttg attccagatg ctctggaaaa cttagccaaa tcaagcacac
    25861 gacatttctc taaaccagag caaacacaac ttcctttaca gtctagggga ctttattatg
    25921 atcctcaaaa gaatgacttt tttgtcaaag agtcggctgt ttctgaaaaa atacctgaga
    25981 ctgattttta ttccggcgct gttgacaaca gtataaaggt tgaaaaagca gagctgttac
    26041 cccactcaga agaagttata ggaccttctt cggttaaaca cgcaagtcgt ccccagaata
    26101 cctttaccga gactgatcat cctaatcttg acttaaaaaa cagacaaaag ttatctcaaa
    26161 tgttgaatcg cttggaaaat gaagaaaaat cagtatttcc tgaattggat tattttggtc
    26221 agatgcatgg gacttatctc tttgctcaag gtaaagatgg cttatttatt atcgatcagc
    26281 atgctgctca agagcgggtt aaatacgaat attatcgtga taagataggt gaggttgaca
    26341 gtagtttaca gcaattgttg gtgccctatt tgtttgagtt ttctggttct gatttcatta
    26401 acttacagga gaaaatggca ctcttaaatg aagttggtat cttcttagaa gtttatgggc
    26461 acaatacttt cattttgagg gagcatccta tctggatgaa agaagaagag attgcatctg
    26521 gtgtctatga aatgtgtgac atgttacttc taaccaatga ggtatctatt aaaacttacc
    26581 gagcagagtt agctattatg atgagttgta aacgatctat caaggcaaat catagcttgg
    26641 atgattattc agcaagaaat ctgctactgc aattggccca atgtcaaaat ccttataact
    26701 gccctcatgg tagacccgta ttgattaatt ttagtaaggc agatatggaa aaaatgttcc
    26761 gtcgaattca agaaaatcac actagcctgc gagagctagg aaaatattag agaggatgag
    26821 atgcaagagt ttttaaacct tcctaagcag attcagctga ggcaactggt acgctttgtg
    26881 accattacct taggcagtag tatctttccc tttatggcca tgtattatac gacttacttt
    26941 ggtacgtttt ggacaggcct cttaatgatg attaccagtt tgatgggatt tgttggaact
    27001 ttatacggtg ggcatctgtc agatgctctt ggtcgcaaaa aagtcattat gattgggtca
    27061 gtaggaacaa cactaggctg gtttctgact attttagcta atttgcctaa tgcagctatt
    27121 ccttggttaa cctttgcggg tattttattg gtagagattg cttctagttt ttatggtcct
    27181 gcctatgaag ctatgttaat tgatttgact gatgagagta atcgtcgatt tgtttacacc
    27241 atcaattatt ggtttatcaa tattgccgtc atgtttggtg cagggctatc tgggcttttt
    27301 tatgaccatc attttttagc cttgttagta gccttattac tcgtcaatgt actttgtttt
    27361 ggcgttgctt actactattt tgatgagact agaccagaaa cacacgcttt tgaccatgga
    27421 aaaggcttgc tggatagttt tcgaaattat cgtcaggtgt ttcaggatcg tgcctttgtc
    27481 ttgtttacct taggtgctat cttttctggt agtatctgga tgcaaatgga taactatgtg
    27541 ccagtacatt tgaaactgta ttttcagcca acggctgtgt taggtttcca agtaactagt
    27601 tctaaaatgt tatcattaat ggttttaact aatacattgc tgattgtcct tttcatgaca
    27661 gtagtaaata aattaacgga aaaatggaaa ctattacctc agcttgtggt tggttcttta
    27721 ctatttactc tagggatgct cttggcattt acctttacgc agttctatgc tatctggtta
    27781 tcagttgttt tgttaacttt tggggaaatg ataaatgttc ctgctagtca agtcctacgt
    27841 gctgatatga tggatcattc ccaaatagga tcttatacag gttttgtgtc aatggcacaa
    27901 cccctaggtg ctattttggc tagtctacta gtatctgtca gccattttac aggtccttta
    27961 ggcgtgcaat gcttatttgt agtcattgct ttgctaggga tttattttac ggttgtttct
    28021 gcaaaaatga aaaaggtgta atatgtacga ttatattaaa ggtcaattga ccaaaattac
    28081 ggcaaaatac attgtcgttg aagctaatgg attgggctac atgattaatg ttgccaatcc
    28141 ttatagcttt acagatagtg tcaaccaatt ggtaaccatt tatctgcatc aagtgattcg
    28201 tgaggatgct cacctgttgt ttggttttca cacggaagat gaaaaagatg tttttctgaa
    28261 attaatttct gtatcaggta ttggtccgac aacagctctt gctattgtgg cagttgatga
    28321 taatgaggga cttgtgaatg ccattgataa cagtgacatt aagtacctaa tgaaatttcc
    28381 taaaattggt aaaaaaacag cgcagcaaat ggttcttgac ttagctggca aatttgtgga
    28441 ggctccacaa gagactggta ataccaaagc gcgcagcaat aaagcaggca atactcaact
    28501 ggacgaagcg attgaagccc tccttgccct cggttataag gcaacggaat tgaagaaaat
    28561 tcgtgccttc tttgaaggaa cctctgagac ggccgaacaa tacatcaaat cagcccttaa
    28621 actattaatg aaaggctagg tgtttcacat gaaacgttgc tcatgggttc ctaaggataa
    28681 ccagctttac tgtgattacc acgatttaga atggggtcaa cccctacatg atgatagaga
    28741 tttttttgaa ttactctgcc ttgaaagtta ccagtcaggc ttatcctggc tgactgtttt
    28801 gaaaaaacgc caagctttca gaactgtttt tcatcattac gacattgcat cggttgcagc
    28861 ctttacctcg gaggaaatgg ctgacgcttt agagaatcta tccatcatcc gccacaagct
    28921 aaagctagca gcaactgtca acaacgctat cgcagtacag aaaattcaaa aagagtttgg
    28981 tagtttttca acttatctct ggaattttgt tgggggaaag ccaattaaca accttgtcaa
    29041 tcaagagaat cttgttcctg ctcaaacaga attatctatt cgcttagcta aggatttaaa
    29101 gaaaagagga tttaaatttt tagggcctac aacggtttat tcttttatgc aagcatcggg
    29161 tctggtaaat gaccatgaag aggcttgtgt tttcaataga atcttctaat tcttcgtgaa
    29221 ttggaagatt ttttgataaa atgagatcag attacgaata gataagtagg tggagaaatg
    29281 aaagctgaac tgattgcagt aggtaccgaa attttgactg gtcaaattgt gaataccaat
    29341 gctcaattta tgtcggaaaa aatggcagag ctaggtattg atgtctattt tcaaacggct
    29401 gttggggaca acgaggagcg tttactttca gtgattacaa ctgctagtca gcgtagtgac
    29461 ttggtgattt tatgtggtgg ccttggtcca acgaaagatg atttaaccaa acaaacttta
    29521 gcaaagtacc ttaggaaaga cttggtttat gatgagcaag cttgtcagaa actagatgac
    29581 ttttttgcta agcgcaagcc ttcatcacgg acaccaaata atgagcgaca ggcacaagtg
    29641 attgaagggt caatctcttt gccaaataaa actggtcttg cggttggtgg gttcatcaca
    29701 gtcgatggta ttagttatgt tgtcttaccg ggtcctccaa gtgaattgaa gccgatggta
    29761 aatgaagaat tggtaccact tctgtcaaaa caatacagta cattgtattc aaaggtacta
    29821 cgcttttttg gtattgggga aagtcagttg gtaacagtct tgtcagattt tattgagaat
    29881 caaactgatc caaccattgc tccgtatgct aagactggcg aagtgactct tcgcttatca
    29941 acaaaaactg aaaaccaagc tctggcagat aaaaagttag gtcagctaga agcgcagcta
    30001 ctatcccgaa aaactcttga aggtcaaccc ttagctgatg tcttttatgg ctatggggag
    30061 gataattcct tagcgcgtga gacatttgag ctcttagtaa aatatgataa gacaattaca
    30121 gcagcagaaa gtctaaccgc gggattattt cagtcaactt tggcgagttt tccaggagct
    30181 tctcaagtat tcaatggagg ctttgtgact tatagcatgg aagaaaaagc gaaaatgcta
    30241 ggccttcctt tagaggagtt gaaatcgcat ggcgttgtta gtgcttatac agccgagggg
    30301 atggcggagc aagcaaggtt attgactggt gctgatattg gggtaagttt aacaggtgtt
    30361 gccggaccag atatgttgga ggaacagcct gcaggtacag ttttcattgg ccttgccact
    30421 caaaataagg tagaatcaat aaaggttttg attagcgggc gaagtcgttt ggatgtgcgc
    30481 tatatcgcta ctttacatgc ctttaatatg gtccgtaaaa ctttattaaa acttgagaat
    30541 ttgctataat gttatttagt agctatagta ggatatggtt tacgattgtg tagattaatc
    30601 ctgctgacga tggtttgtta aaaaagagga gaaagtattg gcaaaaaaat taaaaaagaa
    30661 tgaagaaatc actaagaagt ttggtgacga acgtcgcaaa gcccttgatg atgctttgaa
    30721 aaatattgaa aaagattttg gtaagggcgc agtgatgcga ttaggagaac gtgcagagca
    30781 aaaagttcag gttatgagtt caggaagtct agctcttgat attgcgcttg gagctggtgg
    30841 ttatcctaaa ggacgtatca tcgaaatcta tggtccagag tcttccggta aaacgactgt
    30901 ggctttacat gctgtagcac aagctcaaaa agaaggtgga atcgcagcct ttatcgatgc
    30961 cgagcatgcg cttgatccag cttatgctgc tgcgcttggg gttaatattg atgaactcct
    31021 cttgtctcaa ccagattctg gagaacaagg acttgaaatt gcaggtaaat tgattgattc
    31081 tggtgcggtt gatctggttg ttgtcgattc agtagcagct ttagtgccac gtgctgaaat
    31141 tgatggtgat attggcgata gccatgtcgg attgcaagca cgtatgatga gtcaggccat
    31201 gcgtaaatta tcagcttcta ttaataaaac aaaaactatc gctatcttta ttaaccaatt
    31261 gcgtgaaaaa gttggtgtga tgtttggaaa tcctgaaaca acaccaggtg gtcgagcttt
    31321 gaaattctat gcttctgttc ggctggatgt gcgtggaaca actcaaatta aaggaactgg
    31381 tgaccaaaaa gatagcagca ttggtaagga gaccaaaatc aaggttgtta aaaacaaggt
    31441 cgctccgcca tttaaggtag cagaagttga aatcatgtat ggggaaggta tttctcgtac
    31501 aggggagctt gtgaaaattg cttctgattt ggacattatc caaaaagcag gtgcttggtt
    31561 ctcttataat ggtgagaaga ttggccaagg ttctgaaaat gctaagcgtt atttggccga
    31621 tcatccacaa ttgtttgatg aaatcgaccg taaagtacgt gttaaatttg gtttgcttga
    31681 agaaagcgaa gaagaatctg ctatggcagt agcatcagaa gaaaccgatg atcttgcttt
    31741 agatttagat aatggtattg aaattgaaga ttaaaaagag cccttcaggg ctttttaaaa
    31801 tgtattttta aaggttagta ggactactgt tcataggtgt gtgggtgaat agaaaccatc
    31861 atttaaaaag atgtgagaga gcagaactta ggttaactga tataaaatta aaataactaa
    31921 taattcaagg gaatacaggt gaaaaacctt attttactaa gataatatct tta
//
LOCUS       DATTYN010000020        31573 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.20, whole genome shotgun sequence.
ACCESSION   DATTYN010000020 DATTYN010000000
VERSION     DATTYN010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31573
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.20"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            5..78
                     /locus_tag="VB649_001161"
     tRNA            5..78
                     /locus_tag="VB649_001161"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Asn,seq:gtt)
     gene            158..231
                     /locus_tag="VB649_001162"
     tRNA            158..231
                     /locus_tag="VB649_001162"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:192..194,aa:Arg,seq:acg)
     gene            227..808
                     /locus_tag="VB649_001163"
     CDS             227..808
                     /locus_tag="VB649_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEP1670117.1"
                     /translation="MHNEKSNRTLVSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKV
                     KPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYL
                     KDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQER
                     MQFQALIRGERFKGRRALLRKISPYFKEFAQQL"
     gene            993..1742
                     /gene="truA"
                     /locus_tag="VB649_001164"
     CDS             993..1742
                     /gene="truA"
                     /locus_tag="VB649_001164"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEP1670118.1"
                     /translation="MVRYKATISYDGTLFSGFQRQRHLRTVQEEIEKTLYKLNNGTKI
                     IIHGAGRTDAGVHAYGQVIHFDLPQEQEVEKLRFALDTQTPEDIDVVNIEKVADDFHC
                     RYQKHLKTYEFLVDNGRPKNPMMRHYTTHYPYTLNIKLMQEAINGLVGTHDFTGFTAA
                     GTSVQNKVRTITKATVSRDEKTDFLVFTFSGNGFLYKQVRNMVGTLLKIGNGQMPVEQ
                     VKVILSSKNRQLAGPTISGNGLYLKEICYEN"
     gene            1732..2496
                     /locus_tag="VB649_001165"
     CDS             1732..2496
                     /locus_tag="VB649_001165"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEP1670119.1"
                     /translation="MKTDYIVTISGNDILSGGGLYADLATYIRYDLQAFVAVTCLTTR
                     SEEGFSLFPVAKEIFRDQLNSFTNAPISAIKIGLLPNAEMCEIVLDFIKGHLGIPVVL
                     DPVLACKEIDDVKIVPLRQEILQLLPYVTVVTPNLVEAQLLSQKEIVSLKDMQEAAKY
                     FYQLGAKQVVIKGGNRFSQKKAIDLFYDGKEIVTLECPVLEKNNIGAGCTFASSIASQ
                     LVKKKTPLEAVKNSKELVYQAILQSDRYGVKQSYAK"
     gene            2486..2956
                     /locus_tag="VB649_001166"
     CDS             2486..2956
                     /locus_tag="VB649_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP1670120.1"
                     /translation="MQNSKIRQMSLTGILTALVVVLGRFVMLPTPTGFLTLLDAGIYA
                     VSFSFGSAQGAIVGGLSGFLIDLVAGYPQWMFHSLIAHSVQGYFAGWRGRKRWLGVVI
                     GSFIMIFWYFLGSLVLGYGLSGSLAGIWGNVMQNTLGLFVGFIIFKAILRQKKR"
     gene            2970..3530
                     /locus_tag="VB649_001167"
     CDS             2970..3530
                     /locus_tag="VB649_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEP1670121.1"
                     /translation="MLNNLEKQTREIVIDVVERSAIQPGNLFVLGLSSSEILGSRIGK
                     QSSLEVGQIVVEVVLDELNKRGIHLAVQGCEHVNRALVVERHVAESKLLEIVNVVPNL
                     HAGGSAQMAAFQFMSDPVEVEEVIAHAGLDIGDTAIGMHIKRVQIPLIPCQRELGGAH
                     VTALASRPKLIGGARADYNMDIIRKS"
     gene            complement(3595..4440)
                     /locus_tag="VB649_001168"
     CDS             complement(3595..4440)
                     /locus_tag="VB649_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEP1670122.1"
                     /translation="MTFILHYLEQSHIENIGLTIFKKLVSLIILLLFFAILKRVTNYL
                     FEKTINKSFAYSRQSEARKKTLSKLTHNILNYLLYFLLIYWILSLFGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDNVTISDIEGSVFGVGIRTTQIRGFD
                     GTLHFIPNRSITVVSNKSRGNMRALIEIPLYSTVNLSQVTRIIDEVNQKELPNHPQIV
                     GKPNILGPQNNSNGQFTFRIAIFTENGEQFKIYHTFYRLYQEALLKEGIQLPTAISYS
                     ITSKS"
     gene            4761..6044
                     /locus_tag="VB649_001169"
     CDS             4761..6044
                     /locus_tag="VB649_001169"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEP1670123.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGF
                     RKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGK
                     EWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEA
                     AQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVT
                     FPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKEL
                     EAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEM
                     YFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYN
                     MPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK"
     gene            6261..6836
                     /locus_tag="VB649_001170"
     CDS             6261..6836
                     /locus_tag="VB649_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEP1670124.1"
                     /translation="MKLDVFAGQEKSELSMIEVARAILEERGRDNEMYFSDLVNEIQN
                     YLGKSDAGIRHALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEEDEDG
                     AQKRKKKRVNAFMDGDEDAIDYRDDDPEDEDFTEESAEVEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDINEEDEEDEEDEEPVL"
     gene            7093..8697
                     /locus_tag="VB649_001171"
     CDS             7093..8697
                     /locus_tag="VB649_001171"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEP1670125.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAASTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNSEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLNAPQADMTE
                     WSAMVDKVMNLRKTTKIALVGKYVELPDAYLSVVEALKHSGYANDTAIDLKWVNANDV
                     TVDNAADLLGDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGICLGMQLTCVEFA
                     RHVLNMEGANSFELEPSTKYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKPGSKAAMAY
                     NNQEVVQRRHRHRYEFNNKFRPEFEAAGFVFSGVSPDNRLVEIVELKEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAIKNSN"
     gene            8865..9791
                     /locus_tag="VB649_001172"
     CDS             8865..9791
                     /locus_tag="VB649_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEP1670126.1"
                     /translation="MKTIRIAKYLGILFLLITLISVGASFYFFHVAQIREEKSFINNK
                     KRSTNNPLYPAEQSFDALPYEKRQLTNRGLKQVGWYLPAAQKTKKTAIVVHGFTNDKE
                     DMKPYAMLFHDLGYNVLMPDNEAHGESEGNLIGYGWNDRLNVMAWTDQLIKENPESQI
                     TLFGLSMGAATVMMASGERLPAQVTSLIEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKRPTLFIHGDKDDFVPTKMVYDNYKATKGPKEI
                     LIVKGAKHAKSFETNPEQYQKKITAFLKKVEK"
     gene            9845..9930
                     /locus_tag="VB649_001173"
     tRNA            9845..9930
                     /locus_tag="VB649_001173"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9879..9881,aa:Leu,seq:aag)
     gene            10138..11019
                     /locus_tag="VB649_001174"
     CDS             10138..11019
                     /locus_tag="VB649_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEP1670127.1"
                     /translation="MAIVSAEKFVQAARENGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVCQSLITNLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKTAEVVKIAHAKGVSVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPENWEGLALDHLEKLTAAVPGFPIVLHGGSGIPDDQI
                     KEAIRLGVAKVNVNTESQIAFSNATREFARNYEANEAEYDGKKLFDPRKFLAPGMKAV
                     QGAVEERIDVFGSANKA"
     gene            11401..11589
                     /locus_tag="VB649_001175"
     CDS             11401..11589
                     /locus_tag="VB649_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEP1670128.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            11742..12107
                     /locus_tag="VB649_001176"
     CDS             11742..12107
                     /locus_tag="VB649_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP1670129.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSAIKD
                     NFQSLLRKENYAKGVVVKSTDLGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LTADMVNVYVQNIKVVGEN"
     gene            12107..13771
                     /locus_tag="VB649_001177"
     CDS             12107..13771
                     /locus_tag="VB649_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEP1670130.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQMLSKGLLMGARGNSGVITSQLFRGFGQSIKGKDE
                     LTGKDLAQAFQVGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDDAVEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVTSADFKATPANM
                     SEMINAEHHKSVVGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKTDVEKNKA
                     EVKDFGLIAVVAGEGLSEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVATRTVPQGFTSLLAFDPSKSLEDNVADMSTSLSDV
                     VSGSVTLAVRDTTIDGLEIHENDFLGMVDGKIIVSNPDMEATLKAAFEKMIDEDSEIV
                     TIFVGEEGDQDLAEELAGYLGETYEDVEVEIHQGDQPVYPYLMSVE"
     gene            14008..14898
                     /locus_tag="VB649_001178"
     CDS             14008..14898
                     /locus_tag="VB649_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEP1670131.1"
                     /translation="MLGPFIFIAFGVIIILAIVASTLYVVRQQSVAIVERFGRYQKTA
                     TSGIHVRLPFGIDKIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVTDA
                     YYKLMKPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLAESIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTPSGVEDIRTQVLSALKTK"
     gene            15128..15982
                     /locus_tag="VB649_001179"
     CDS             15128..15982
                     /locus_tag="VB649_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEP1670132.1"
                     /translation="MKSKKVVSVISLTLSLFLVTGCAKVDNNKSVNRKPATKQTYNSY
                     SDDQLRSRENTMSVLWYQRAAETQALYLQGYQLATDRLKEQLNKPTDKPYSIVLDIDE
                     TVLDNSPYQAKNVLEGTGFTPESWDYWVQKKEAKPVAGAKDFLQFADQNGVQIYYISD
                     RSTTQVDATMENLQNEGIPVQGRDHLLFLEKGVKSKESRRQKVKETTNVTMLFGDNLL
                     DFADFSKKSQEDRTALLSDLQEEFGRRFIIFPNPMYGSWEGAIYKGEKLDVLKQLEER
                     RKSLKSFK"
     gene            16175..17371
                     /locus_tag="VB649_001180"
     CDS             16175..17371
                     /locus_tag="VB649_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEP1670133.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVVFPGVTRGSKLEE
                     AINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGNGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKDLLEKSNGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAEFDQALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            17634..18185
                     /locus_tag="VB649_001181"
     CDS             17634..18185
                     /locus_tag="VB649_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEP1670134.1"
                     /translation="MKTLRKLLSNYKFDIKKFKLGMRTLKTGLSVFLVLLVFHLFGWK
                     GLQIGALTAVFSLREDFDKSVHFGFSRIIGNSIGGLLSLVFFAFNEIFHQAFWVTLLI
                     VPICTMLCIMVNVACNNKSGIIGAVAALLIITLSIPTGQTFIYVTSRVFETFCGVFVA
                     ILVNTDVELIKNKWFNKKHSDVS"
     gene            18252..18623
                     /locus_tag="VB649_001182"
     CDS             18252..18623
                     /locus_tag="VB649_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEP1670135.1"
                     /translation="MKEKELRRSMAVFPIGTVMTLTDLSARQIRYYEDQGLIKPERTQ
                     GNRRMFSLNDMDRLLEIKDFLSEGLNIAAIKREYVERQGKLMQKQKALTDADVRRILH
                     DEMLTQSGFSTPSQHIGNFRI"
     gene            18661..20007
                     /gene="glnA"
                     /locus_tag="VB649_001183"
     CDS             18661..20007
                     /gene="glnA"
                     /locus_tag="VB649_001183"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEP1670136.1"
                     /translation="MAITVADIRREVKEKNVTFLRLMFTDIMGVMKNVEIPATKEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGAVAGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMNEIGYKSFNLGPEPEFFLFKMDDKGNPTLEVNDNGGYFDL
                     APIDLADNTRREIVNILTKMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDNQGNNAFYDEADKRGMQLSEDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPEPVEANIYTMTMEERNEAGIIDL
                     PSTLHNALKALQKDDVVQKALGYHIYTNFLEAKRIEWSSYATFVSQWEIDHYIHNY"
     gene            complement(20235..21917)
                     /locus_tag="VB649_001184"
     CDS             complement(20235..21917)
                     /locus_tag="VB649_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEP1670137.1"
                     /translation="MTNISLKPNEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLDRVKALVITHGHEDHIGGIPFLLKQANIPIYAGPLA
                     LALIRGKLEEHGLWREATVYEINHNTELTFKNMSVTFFKTTHSIPEPVGIVIHTPQGK
                     IICTGDFKFDFTPVGDPADLQRMAALGEEGVLCLLSDSTNAEIPTFTNSEKVVGQSIL
                     KIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPSELKNLHASEVLIMCTGSQGESMAALARIANGTHRQVTLQPGDTVIFSSS
                     PIPGNTTSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAMDIGIPKENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGAAVLRDRRDLSEDGVVLAVATVDFSTQMILAGPDILSRGFIYMRESGDLIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDKH"
     gene            complement(21919..22149)
                     /locus_tag="VB649_001185"
     CDS             complement(21919..22149)
                     /locus_tag="VB649_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEP1670138.1"
                     /translation="MIYKVFYQETKDQSPRRESTKALYLNIDATDELDGRIKARRLVE
                     DNTYYNVEFIELLSDKHLDYEKETGVFELTEF"
     gene            22433..23131
                     /gene="tsaB"
                     /locus_tag="VB649_001186"
     CDS             22433..23131
                     /gene="tsaB"
                     /locus_tag="VB649_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEP1670139.1"
                     /translation="MKTLAFDTSNKTLSLAILDDEILLADMILNIQKNHSVSLMPAID
                     FLMTSTDLKPQDLERIVVAKGPGSYTGLRVAVATAKTLAYSLNIALVGISSLYALAAS
                     TCKQYPNTLVVPLIDARRQNAYVGYYRQGKSVMPQAHASLEVIIEQLVEEGQLIFVGE
                     TAPFTEKIQKKLPQAILLPTLPSAYECGLLGQSLAPENVDAFVPQYLKRVEAEENWLK
                     DNEIKDDSHYVKRI"
     gene            23103..23558
                     /gene="rimI"
                     /locus_tag="VB649_001187"
     CDS             23103..23558
                     /gene="rimI"
                     /locus_tag="VB649_001187"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEP1670140.1"
                     /translation="MIVTTLSESNMKTVEEQAKNIYQLLEMVYGTSPWTLEQVLIDIR
                     RDQTDYFLLYDRDKLLGFLAIQDLAGEVEMTQIAILPSHQELGLASQLMTHLDSIESD
                     IFLEVRESNHRAQGLYQKFGFKFIGKRPDYYRNPIETALLMKREGKHDR"
     gene            23548..24576
                     /gene="tsaD"
                     /locus_tag="VB649_001188"
     CDS             23548..24576
                     /gene="tsaD"
                     /locus_tag="VB649_001188"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEP1670141.1"
                     /translation="MTDRYILAVESSCDETSVAILKNESTLLSNVIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFEDALQEAGISASDLSAVAVTYGPGLVGALLVGLAAAKAFA
                     WANHLPLIPVNHMAGHLMAAREQKPLVYPLIALLVSGGHTELVYIPEPGDYHIIGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDQLAHKGQDTYHFPRAMITEDHLEFSFSGLKSA
                     FINLHHNAKQKGDELILEDLCASFQAAVLDILLAKTKKALSRYPAKMLVVAGGVAANQ
                     GLRDRLAQEITHIEVVIPKLRLCGDNAGMIALAAAIEYDKQHFANMSLNAKPSLAFDQ
                     FPDSFVIN"
     gene            complement(24747..25016)
                     /gene="rpsN"
                     /locus_tag="VB649_001189"
     CDS             complement(24747..25016)
                     /gene="rpsN"
                     /locus_tag="VB649_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEP1670142.1"
                     /translation="MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSN
                     PNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW"
     gene            complement(25236..25994)
                     /locus_tag="VB649_001190"
     CDS             complement(25236..25994)
                     /locus_tag="VB649_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP1670143.1"
                     /translation="MSTNDLTKKLKKLKHVQVYNTIFQLIQDGTYSPGMQLPSEPELA
                     RQLNVSRMTLRKSLALLQEDHLIKNIRGKGNFILKTPETKYHQGFEYLQHPIYASLSS
                     DITKVELEYRIEVPTVAITASLKQETPVVIIVDRWYHSQNKAIAYSLSFIPIEVISKY
                     AINLNQEEPLLTFLEEKIYESGKASHSCNQIGYTKTGNYTATKYTLSENSAFILIQET
                     LYNGKDILVSTKHYVPADLFDLKVQSQSCQSDTH"
     gene            26234..27013
                     /gene="udp"
                     /locus_tag="VB649_001191"
     CDS             26234..27013
                     /gene="udp"
                     /locus_tag="VB649_001191"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HEP1670144.1"
                     /translation="MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNA
                     VLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGID
                     LDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQ
                     CKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFL
                     VVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ"
     gene            27034..28236
                     /locus_tag="VB649_001192"
     CDS             27034..28236
                     /locus_tag="VB649_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HEP1670145.1"
                     /translation="MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIAL
                     ILVRIPLGQQIVSVVSTGVTSVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVF
                     LSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYL
                     GRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQ
                     TEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLS
                     GLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLD
                     YRTALVATISLCGFANLSSLGICVSGIAVLCPEKRSTLARLVFRAMIGGIAVSMLSAF
                     IVGIVTLF"
     gene            28266..28937
                     /gene="deoC"
                     /locus_tag="VB649_001193"
     CDS             28266..28937
                     /gene="deoC"
                     /locus_tag="VB649_001193"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEP1670146.1"
                     /translation="MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPAS
                     YVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNG
                     DFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFST
                     AGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEAT
                     KTDSY"
     gene            complement(29032..30201)
                     /locus_tag="VB649_001194"
     CDS             complement(29032..30201)
                     /locus_tag="VB649_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEP1670147.1"
                     /translation="MTQYDTIIIGGGPAGMMAAISSSYYGYKTLLIEKNRRLGKKLAG
                     TGGGRCNVTNSGNLDDLMAGIPGNGRFLYSVFSQFDNHDIIAFFEENGVKLKEEDHGR
                     MFPTTDKSRTIIDALEKKIKALGGQVLTSTEMVSVKKQDDLFYLKSADQTFTCQKLIV
                     ATGGKSYPSTGSTGFGHDIARHFKLTVTDLEAAESPLLTDFPHKVLQGISLDDVTLSY
                     DKHVITHDLLFTHFGLSGPAALRLSSFVKGGEIAELDFLPHLSTDDLIAYLSDQRDKN
                     IKNALKGLLPERVADFLSEDYPEKVKQLSPKQEKELLDKLKHLQIPITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLYFAGEVLDINAHTGGFNITSALCSGWIAGKSS"
     gene            30462..30800
                     /locus_tag="VB649_001195"
     CDS             30462..30800
                     /locus_tag="VB649_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670148.1"
                     /translation="MKKRFNSKAITLLAVSSLSLGFTAVTSVVSAATAHPAPSPIIDE
                     WNYGVSDNYGYSNYYVKSPNNIGSKSSITNYWGSIKASDSQKYGWALSSSKKAWNDIR
                     LNAHWNYFNF"
     gene            30868..>31573
                     /locus_tag="VB649_001196"
     CDS             30868..>31573
                     /locus_tag="VB649_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670149.1"
                     /translation="MKLKLSVIGLFFCLIAAIGVISISDTQKPVPLPIDGAFSIQGKS
                     SLSSDEVYKKISNLSKMKNVNIYKPIVRNSGQLTYINFKNTNYEQLKSAPITGMYYTL
                     GKIDSSSLKVLTASGLKLVYAAYPWYIGGILQFDGTLRLLLMLSIYLTLLVVLFVVRT
                     RQIKEGVIRHSLGLPIYNLRRDYVISFTFELVMAGLLMIAYSYFWGSGLFTYSSKLFF
                     SLILTNLIIFQIVDIIT"
BASE COUNT        10029 a         5120 c         6662 g         9762 t
ORIGIN      
        1 tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat gtcgtaggtt
       61 cgagtcctac tggcggagta gagagaggta gggagcgtcc tatctttttt tgcattttag
      121 agaagagtgt ggtaagatag aggcaagata tgcgttggca cccttagctc aactggatag
      181 agtacctgac tacgaatcag gcggttagag gttcgactcc tctagggtgc ataatgaaaa
      241 aagcaacagg acattagtgt cctgttgttt ttttgtggtt ctctttatac tagggatagt
      301 taaaaagaaa aggagactca aaatgtcgat agagacaaga gcagcgtttg aaaaagttaa
      361 gcccattatt ttgaaattaa agcgacacta ttatattcaa ttgtgggata gagatgactg
      421 gttacaagaa ggacatatta tcttattaca gttactagaa aggtacccag agttaattga
      481 ggaagaagag cgtttatatc gctattttaa aacaaaattt tcatcttatt tgaaagattt
      541 attacgccgt caagaaagtc aaaagcgtca gttccataag ttagcatatg aagagatagg
      601 ggaggttgca catgccattc catcgagagg gttatggcta gacgactatg tggcttatca
      661 agaggtaata gctagcttag agaaccaatt aaattcgcaa gagcgtatgc agtttcaagc
      721 acttatcagg ggcgaacgtt tcaagggaag acgtgctcta cttaggaaga tcagtcccta
      781 ttttaaggaa tttgcacagc agttgtaagc aagatctata aggaattggg ggtaaatcta
      841 tgaaaaaagg agagagtttg gaggaaatag ctttcttata gcttttaaat cgttagtagc
      901 ttagagtaag cttcaatacg tctttcattt gtttgggtac agtttgatta aaaatagttt
      961 ctcttacgtt taagaaatgt taaaatagta acatggtaag atacaaagca acgatttcct
     1021 atgatgggac tcttttttcg ggttttcaaa gacaaagaca tttacgtacg gttcaagaag
     1081 agattgaaaa aacactctat aaattaaata acggtacaaa aattataatt catggtgcag
     1141 gacgtacgga tgcaggagta catgcttatg gacaggtgat ccattttgat ttgcctcaag
     1201 aacaagaagt tgaaaaatta cgatttgctc ttgatacaca gactcctgaa gatattgatg
     1261 ttgttaatat agaaaaagtg gctgatgatt ttcattgtcg ttatcagaag catttaaaaa
     1321 cttatgaatt tttagttgat aatggtcgac ctaaaaatcc gatgatgcga cactatacca
     1381 ctcattaccc ttatactctt aatattaaac ttatgcaaga agctattaac ggtctggtag
     1441 gtacacacga ttttactggt tttacagcag caggaacttc ggtacaaaat aaggtgcgaa
     1501 cgattaccaa agcaacggta tctcgggatg aaaaaactga ttttttggtg tttacttttt
     1561 caggaaatgg ttttctctat aagcaggtga ggaatatggt gggaactttg ctgaaaattg
     1621 gtaatggtca aatgccagtt gaacaagtta aagtgatttt gagctccaaa aatcgtcagc
     1681 tagctggacc aacgatatct ggaaatgggc tttacttgaa ggagatttgt tatgaaaact
     1741 gattatatcg tgactatatc tgggaacgat attttaagtg gaggtggtct ctatgctgat
     1801 ttagcgactt acataaggta tgacctacag gcctttgtag cggtaacttg tttaactact
     1861 agatctgaag agggctttag tctatttccg gtagctaaag aaattttccg tgatcagttg
     1921 aatagcttta cgaacgctcc aatttctgct attaaaattg gtttgttacc taatgcggaa
     1981 atgtgtgaaa tagttttgga ttttataaag gggcatctgg gaatcccagt ggttttagat
     2041 cctgttctag catgtaaaga aatagatgat gttaaaatag ttcctctaag acaggagatt
     2101 ttacaattat tgccttatgt gactgttgtt actccaaatt tggtagaggc tcagctatta
     2161 tctcaaaaag agattgtttc tttaaaagat atgcaagaag ctgctaaata tttttatcaa
     2221 cttggggcaa aacaggtggt tatcaagggt ggtaatcgat ttagtcagaa aaaggctatt
     2281 gatctttttt atgacggtaa agagattgtt accttggaat gtcctgtact tgagaaaaat
     2341 aatattggcg caggctgtac ttttgcatct agtatcgcta gtcagttagt aaagaaaaaa
     2401 acgccactag aagctgtgaa aaactcaaaa gagttagtct accaagctat tttacaatct
     2461 gatagatacg gagtaaaaca aagttatgca aaatagtaag atacgacaaa tgagtttaac
     2521 agggatattg acagcattgg ttgttgtttt aggaagattt gtcatgctac ctactccaac
     2581 aggtttttta acgctgttgg atgcaggaat ttatgctgtc agcttttcct ttggatcagc
     2641 tcaaggagct attgtgggag ggttatcagg ttttttaatc gatttagtgg caggataccc
     2701 tcagtggatg tttcatagtt tgattgctca cagtgtccaa gggtattttg cgggatggag
     2761 agggcgcaag cgttggcttg gtgttgtgat aggttctttt atcatgattt tttggtactt
     2821 tttaggctct cttgtgcttg gttatggcct ttcgggatct ttagccggta tttggggaaa
     2881 cgtcatgcaa aatacattag ggctttttgt tggttttatt atctttaagg ccatattaag
     2941 gcaaaaaaag agataaggag agtgagaagt tgttgaataa tttagagaaa caaacaaggg
     3001 aaatcgtcat tgatgttgta gaacgctctg ctattcaacc aggtaatctt tttgttctag
     3061 gtctttcatc tagcgaaatt ttgggtagta gaattggaaa acaatctagt ctagaagtag
     3121 gtcaaatagt tgttgaagtt gtgttagatg aattaaataa gcgtggtatt catttggctg
     3181 tacaaggttg tgaacatgtc aatcgtgcct tggtagtaga gaggcatgtg gcagaatcta
     3241 agctgttaga gattgtcaat gtggttccga atcttcatgc tggtggcagt gctcagatgg
     3301 ctgcttttca atttatgtca gaccctgtcg aagtagaaga agttattgca cacgctggac
     3361 ttgatatagg tgatactgct ataggaatgc atattaagcg tgttcagatc cctctgattc
     3421 cttgtcaacg agagctagga ggtgctcatg tgacagcttt ggctagtcga ccaaaattaa
     3481 ttggtggagc tagggctgat tacaatatgg atattatccg taaatcctaa accctttttt
     3541 ctggaataaa acaattggtg ttttttctag aaaaaaggat tttttaagat tatattaaga
     3601 ttttgaggtg atagaatagc tgattgcagt cggtaattga atgccttctt tgagtaaagc
     3661 ttcttgataa agtctataaa aagtatggta aatcttaaat tgttctccat tttctgtgaa
     3721 aatagcaatt ctaaaagtga actgtccatt agagttattt tgaggcccta aaatatttgg
     3781 tttgccaacg atttgaggat ggtttggcaa ttccttttga ttcacttcat caatgattcg
     3841 agtgacttgg ctcaaattaa cagtggaata aagaggaatt tcaattaagg cacgcatatt
     3901 accacgagat ttgttgctga caacggtgat gctacggttt gggatgaaat gtagtgttcc
     3961 atcgaatcca cgaatttgag tagttctaat tccaacacca aagacactgc cttctatgtc
     4021 agagatagta acgttatctc ctacttcaaa ttgattctca aataagataa aaaagccatt
     4081 gacaacgtca gataaaaatc cctgtgcacc taacccgatt gctactccag caattccagc
     4141 tcctgctaga agactagaga caggtatgcc aaataagcta agtatccaat aaatgagaag
     4201 aaaatataat aagtaattta aaatgttgtg agtgagctta gagagtgttt ttttgcgagc
     4261 ttcactttgt cttgaataag caaacgattt gttaatggtt ttttcaaaaa gatagttagt
     4321 aacacgtttt aaaatagcaa aaaagagtaa tagaataatg agagacacta gctttttaaa
     4381 aatcgttaag ccaatatttt cgatatgaga ctgctctagg taatgtaata taaatgtcat
     4441 gagaaatcct ttctttgata gtttatcaaa aaaaaaccaa tcttgaaaag agataaatta
     4501 atattttaac caaagttatg ataattgttt tatcataaag aatgccatag tcatccgttg
     4561 tgataatgct tgaaaatagt cagttagtaa gcgaaaaagt ctaacattaa cctttataaa
     4621 ttgaaaataa ctgttagtag actaatgaca ggtagatact cttaatagcg cgtttgattt
     4681 cacgcataaa aagctttaaa aacgctttaa attatgataa aatgaactgt atcgaaatta
     4741 ttttaaggag aaatgactta atgtctacat catttgaaaa caaagctaca aatcgtggcg
     4801 tgattacatt tacaatcagt caagataaaa taaaaccagc tcttgataaa gcttttaaca
     4861 aaatcaaaaa agacttgaat gcaccaggtt tccgtaaagg acacatgcct cgtccagtct
     4921 tcaaccaaaa atttggtgaa gaagttcttt atgaagatgc tttgaatatt gtattgccag
     4981 aagcttatga agcagctgtg acggaacttg gtcttgatgt ggttgcacaa ccaaaaatcg
     5041 acgttgtgtc aatggaaaaa gggaaagagt ggacactttc tgctgaagtt gtgacaaaac
     5101 ctgaagtgaa acttggtgat tacaaaaacc ttgttgtaga agttgatgct tcaaaagaag
     5161 tttcagatga agacgtggat gctaaaattg agcgcgaacg tcaaaacctt gcggaactca
     5221 ttattaaaga cggtgaagca gctcaaggtg acactgttgt gattgacttt gttggttcag
     5281 ttgatggtgt tgagtttgat ggcggtaaag gagataactt ctctcttgaa cttggttcag
     5341 gacaatttat cccaggtttt gaagatcaac tagttggtgc taaagctggc gatgaagtag
     5401 aagttaatgt cacattccca gaatcttacc aagcagaaga tcttgcaggt aaagccgcta
     5461 aatttatgac aactattcac gaagtcaaaa caaaagaagt accagagctt gatgatgagc
     5521 ttgcaaaaga tattgatgaa gatgttgaca cacttgaaga cttaaaagta aaatatcgta
     5581 aagaacttga agcagctcaa gaaactgctt atgatgatgc tgttgaagga gctgcgattg
     5641 aattagcagt tgcaaatgct gaaattgttg atttacccga agaaatgatt catgaagaag
     5701 tcaaccgttc agtgaatgaa tttatgggca acatgcaacg tcaaggaatc tcacctgaaa
     5761 tgtacttcca attgactggt acaactcaag aagatttaca taaccaatat tcagctgaag
     5821 ctgacaaacg tgttaaaaca aaccttgtta ttgaagcaat tgctaaagca gaaggttttg
     5881 aagcaacaga tagtgaaatt gaacaagaaa ttaatgacct tgcaacagaa tataacatgc
     5941 cagctgacca agttcgttct cttctttcag cagatatgtt gaaacatgat attgcaatga
     6001 aaaaagcagt tgaagtgatt acaagtacag caagcgttaa gtaatcttat taaggaacaa
     6061 aacggacaag ccggattaga acgtctttct agtctggttt ttctttttct aaagaaataa
     6121 taaggaatta attaaacgtt attttaatga attagcttta aagatttgtc aagaagaagt
     6181 gatatgagtt gataaaagtt ttgacgaatt acttttttta gcgtaaaatg gtagagaatg
     6241 ataaaataag gagaactgcc ttgaaattag acgtatttgc aggacaagaa aaaagcgagc
     6301 tttccatgat tgaagtggcg cgtgccattt tggaagaacg cggtcgcgac aatgagatgt
     6361 actttagcga tttagtcaat gagattcaaa attacttagg aaaatctgat gcaggtattc
     6421 gtcatgcatt accatttttc tatactgact taaatacgga tggctcattt attcctctag
     6481 gtgaaaacaa atggggactt cgttcgtggt atgctattga tgaaattgat gaagaaatta
     6541 ttactctaga agaagatgaa gatggcgcac aaaaacgtaa gaaaaaacgc gttaatgctt
     6601 tcatggatgg agatgaagac gctattgatt atagagatga tgatccagaa gatgaagatt
     6661 tcacagaaga atcagctgag gttgaatatg atgaagaaga tccagatgat gaaaaatcag
     6721 aagtggagtc atatgattca gaattgaatg aaattatccc tgaagatgat tttgaagaag
     6781 ttgatatcaa tgaagaagac gaagaagatg aagaagatga agagccagtt ctctaatgtt
     6841 tttagttcag aaataaaaat gtaattatca tttgacaaat tatctattat agtttatatt
     6901 attattcggg cacctcttta agaggtcagg caaaagctct ctagttaata gggggctatt
     6961 tttgttttct agaataatgc cagtttgcct ctatatttag aaaactaagg tgatacctaa
     7021 ccaatgtgga accaactaat agggaattaa caagaaagca atgcttttat tcagcttata
     7081 taaaggagta ctatgacgaa atacattttt gtaactggtg gtgttgtatc atcaattggc
     7141 aaaggaattg ttgcggcaag tcttggccga ttgttaaaaa atcgtggact taaggtgacg
     7201 attcaaaaat ttgatcctta tattaatatt gatccaggga cgatgagccc ctatcagcat
     7261 ggagaagtat atgtgacaga tgacggtgct gaaaccgact tggatttggg tcactatgaa
     7321 cgttttattg atatcaatct taataaatat tccaatgtta caacaggtaa aatttatagt
     7381 gaagtccttc gtaaagaacg taaaggcgag taccttggag ctactgttca ggtgattcct
     7441 catatcacag atgcccttaa ggaaaaaatc aaacgcgcag cttcaacaac ggactctgat
     7501 gtaattatta ctgaggtcgg ggggactgtt ggcgatattg aaagtttacc gttcttagaa
     7561 gctcttcgtc agatgaaagc tgatgttggt tctgaaaatg tgatgtatat tcacaccacc
     7621 ttgttgccat atttaaaggc agcgggtgaa atgaaaacta agccaacgca acattccgtt
     7681 aaagaattgc gtggtttagg gattcaaccg aatatgttgg ttattcgtac ggaagagcca
     7741 gttgagcagg ggattaaaaa taaattggct cagttctgtg atgtgaattc agaagctgtt
     7801 atcgagtcac gtgatgtaga acacttgtat caaattccat tgaacttgca agctcaatca
     7861 atggatcaga ttgtttgtga tcatttgaaa ttgaatgcgc cacaagctga tatgaccgag
     7921 tggtcagcta tggttgacaa ggtgatgaat ttaagaaaaa caacaaaaat tgccttggtt
     7981 ggtaaatatg tggaattgcc agatgcctac ttatctgttg tggaagcctt gaaacattct
     8041 ggttatgcca atgataccgc aattgaccta aaatgggtca atgctaacga tgtgacggtg
     8101 gataatgcag ctgacttgtt gggagatgcg gatgggatta ttgtaccagg tggttttggt
     8161 caacgtggta cagaaggcaa gatccaagcg attcgctatg cccgcgaaaa tgatgtgcca
     8221 atgcttggta tctgtcttgg catgcagttg acttgtgttg aatttgcccg ccatgttctc
     8281 aatatggaag gtgcaaactc ttttgaatta gagccaagta ctaaataccc catcattgat
     8341 atcatgcgtg atcaaattga tattgaagat atgggaggta cgcttcgtct gggattgtac
     8401 ccatgtaaat tgaaaccagg ttcaaaagca gcaatggctt acaataatca agaggtggtg
     8461 caacgtcgtc atcgtcaccg ttatgagttc aacaacaaat tccgtccaga atttgaagca
     8521 gctggttttg ttttctcagg ggtatcacct gacaaccgct tagttgaaat tgtagaattg
     8581 aaagagaaaa aattctttgt agcagctcaa taccacccag aattgcaaag ccgtccaaat
     8641 cgtcctgagg agctatacac cgcttttgtt acagctgcta ttaaaaatag caattagtgg
     8701 ttttaagggt aagtttgtgg cattctactt ggctggcaga tactgataaa gattactagc
     8761 tattaaaggg atcttttcta taaaaatagc attagaaaaa gaaaaacgtg atatttttag
     8821 gttagcactt tctttttcag tcattttttt gtaaaatact tggtatgaaa actattcgaa
     8881 tagcaaagta tttaggaatt ctattccttt tgataactct tattagcgta ggtgctagtt
     8941 tttatttctt tcatgttgca caaataagag aagagaaatc gtttattaat aataagaaac
     9001 ggagtacaaa taatccatta tacccagctg aacagtcttt tgacgcttta ccttacgaaa
     9061 aacgtcaact aacaaatcgt gggttaaaac aagtggggtg gtacttacca gctgctcaaa
     9121 aaacaaaaaa gacagctatt gttgttcatg gttttacgaa tgacaaagaa gatatgaagc
     9181 catatgccat gctttttcat gatttgggct ataatgtctt aatgccagac aatgaggccc
     9241 atggggaaag tgaagggaac ttgattggtt atggctggaa tgatcgcctt aatgtcatgg
     9301 cttggacaga ccaactgatt aaggaaaacc ctgaaagcca aatcacactc tttggcttat
     9361 ctatgggtgc tgcaacagta atgatggcaa gtggtgagcg attgcctgcg caagtcacct
     9421 ccctcatcga agattgcggt tataccagtg tttgggacga attgaagttt caggccaagg
     9481 ctatgtacaa cttgcctgcc tttcctttac tctatgaagt ctctgcctta tctaagattc
     9541 gagcaggttt tagttacgga gaagcgagct cagtgaaaca gctggctaaa aataaacgtc
     9601 caactttatt tatccacggt gataaggatg attttgttcc tacaaaaatg gtttatgaca
     9661 attataaggc cacgaaaggt cctaaggaaa tcttgattgt taaaggggca aaacacgcca
     9721 aatcctttga aacaaaccca gaacaatacc agaaaaaaat taccgctttt ttgaaaaaag
     9781 ttgagaaata agtattgaca gttaaactca cagttgctat aataatttat gttactgatg
     9841 agtagcgggg atggcggaat tggcagacgc gcaggactaa ggatcctgtg accgctttag
     9901 gtcgtgtggg ttcaagtccc actctccgca taatgtaaga ggtgaatcat tgattcgtct
     9961 ctttttgttt ggttaaatga aggataagaa ggcatagatt taccggagaa aacttttgat
    10021 aatctgcttt tggaaaacgc tttaagcttg tgaaagacta gaaatttatg gaaaattgtg
    10081 ctagaatgaa caatgtaaac ggggagttat cccgaaaaat aagaggaggc cttacaaatg
    10141 gcaatcgttt cagcagaaaa atttgtccaa gcagctcgtg aaaacggata tgctgttggt
    10201 ggatttaaca caaacaactt agagtggact caagcaatct tgcgtgcagc agaagctaaa
    10261 caagctccag ttcttatcca aacatcaatg ggtgcagcaa aatacatggg tggttataaa
    10321 gtatgtcaat ctcttattac taaccttgtt gagtcaatgg gtatcactgt tcctgttgct
    10381 atccaccttg atcatggtca ctacgaagat gctcttgagt gtatcgaagt aggttacact
    10441 tcaatcatgt ttgacggttc acaccttcca gttgaagaaa accttgctaa aactgcagaa
    10501 gttgttaaaa ttgcacatgc taaaggcgtt tcagttgaag ctgaagttgg tacaatcggt
    10561 ggtgaagaag acggtatcat cggtaaaggt gagctcgctc caatcgaaga tgctaaagca
    10621 atggttgaaa ctggaattga cttcttggca gctggtatcg gtaacatcca cggtccatac
    10681 ccagaaaact gggaaggtct tgctcttgac cacttagaaa aattaacagc agctgtacca
    10741 ggtttcccaa tcgtattgca cggtggttct ggtattcctg acgatcaaat caaagaagca
    10801 atccgtcttg gtgttgctaa agttaacgtt aacactgaaa gtcaaatcgc tttctctaac
    10861 gcaactcgtg aatttgctcg taactacgaa gctaacgaag cagaatatga tggtaaaaaa
    10921 ttatttgacc cacgtaaatt cttggctcca ggtatgaaag ctgttcaagg tgctgttgaa
    10981 gaacgtatcg atgttttcgg atcagctaac aaagcataat ttagagtatt aaatacccta
    11041 aagccctctt gagggctttt ttagatacaa ttgacatctt aaaatggata ccagtttctg
    11101 tgaaacaatc tttgattgtg aacaaacaaa gcataattta gagtattaaa atctggaccc
    11161 tgctatctat ggtaagtctt tttgttattg ttaaagaggt taagcggaat gttaatatgt
    11221 tttagctaaa aaatgtagtg aaaaatgagt acgtagacta ttgtaatagt aattccgtaa
    11281 aattgttgaa aaagaaaatg ggaaatacct tgtcaaatta agcaccctat gatagaatag
    11341 ataggtatgt ggtgctagca catccgtaaa catattctac gtaggaggaa acagatcaaa
    11401 atggctaaag tatgttattt tacaggacgt aaaaccgttt ctggaaacaa ccgttcacac
    11461 gcgatgaacc aaacaaaacg tacagttaaa ccaaaccttc aaaaagttac tatccttgtt
    11521 gatggtaaac ctaaaaaagt ttgggcttct gctcgtgcgc ttaaatctgg taaagtagaa
    11581 cgcatctaat agaaataagc cttagggctt ttttttatta gcttatttct atccataagc
    11641 tagtcaaggt aataaacgct atcgttaact attctatctc ttttacatta cttctaaaat
    11701 atgataaaat aggatgataa aaactttttg aggtagtaac tatgactgta aaaattaata
    11761 caaaagatgg tctaatcgag ctatccgacg atgtgattgc aactgtcgtt ggaggatcag
    11821 caacggaaat ttttggtgtt gttggaatgg ccagcaaaag tgcaataaaa gacaattttc
    11881 aatcactact tcgcaaagaa aactacgcta agggtgttgt agtaaaatca acagatctgg
    11941 gtatttctgt tgatgtctac actgtgatga gttatggtgt gaaaatcagt gaagtctcta
    12001 aaaatatcca agaacgcgtg aaatttaacc ttgaaagtca gcttggtctc actgctgata
    12061 tggtcaatgt ttacgtgcaa aatattaagg ttgtaggaga aaattagtgt caaatattac
    12121 aacaagctta ttccaagaaa tggtccaagc ggcagcgact cgccttggca aacaagcaga
    12181 atatgttaat tccttaaatg tttttcctgt tccagatggt gatacaggaa caaacatgag
    12241 catgactatg gacaatggtg ccaaggaagt tgctgataaa cctgcgtcaa ctgtgggaga
    12301 agttggacaa atgttatcaa aaggtctttt gatgggagcg cgtggaaatt ctggagttat
    12361 tacttcacaa ctttttcgtg gttttggtca aagcattaag ggaaaagatg agctgacagg
    12421 taaagatttg gcacaagcct ttcaagtggg tgtagaagtt gcctacaaag cagtgatgaa
    12481 acctgttgaa ggaacaattt taactgtttc tcggggtgca gcgactgctg ccttaaaaaa
    12541 agcagacctt acagacgacg ccgtggaagt catgcaagct gctttagatg gtgccaaagg
    12601 tgcccttgct aagactcctg atttacttcc tgttcttaaa gaagttggtg tggttgattc
    12661 aggcggtcaa ggtcttgtct ttatctatga aggtttccta tctgctttga atggcgacta
    12721 tgtgacttca gcagacttta aagcgactcc tgctaacatg tctgaaatga ttaatgctga
    12781 gcatcacaaa tccgttgttg gtcatgtggc tactgaagac attacctacg gttattgtac
    12841 tgaaatcatg gttgccctta aacaaggccc aacctatgtg aaagaattca actatgatga
    12901 gtttcaaggc taccttagtg gccttggtga ctcgctgtta gtggtcaatg atgatgagat
    12961 tgttaaagtt cacgtccata ctgaagaccc cggacttgtg atgcaagaag gtcttaaata
    13021 tggttcgctc atcaagatta aagtggacaa tatgcgtaac cagcatgaag cacaggttca
    13081 aaagactgat gtcgaaaaaa acaaggctga agtaaaagac tttggcttga ttgcagtagt
    13141 agctggagaa ggtttatctg aaatttttaa ggcgcaaggt gttgattacg tgatttctgg
    13201 tggtcaaacc atgaatccat ctacagaaga tattgttaaa gctattgaag cagttaatgc
    13261 caaacaagtc attatcttgc caaacaataa aaatatcttt atggctgccc aatctgctgc
    13321 agaagtggtg gatattccgg ctgctgttgt tgcaacacgt actgttccgc aaggatttac
    13381 cagcttgtta gcctttgatc cttcaaaatc tttagaggac aatgtagcag atatgtcaac
    13441 tagtctttct gacgtggtca gtggaagcgt tactttggca gtccgtgaca ccaccattga
    13501 tggtttagaa atccatgaaa atgatttctt gggaatggtt gatggtaaaa tcatcgtttc
    13561 aaacccagac atggaagcaa ctctaaaagc tgcctttgaa aagatgattg acgaagatag
    13621 cgagattgtg actatctttg ttggtgaaga aggtgatcaa gacttagcag aagaacttgc
    13681 tgggtattta ggagagactt acgaagatgt ggaagttgag atccatcaag gagatcagcc
    13741 tgtttaccca tatctcatga gtgtagaata atagaataca ataaaaaaag aggagttagg
    13801 caaaggtctg actctttttg tctatattga tgtcgtaatg agtggtttta gtgatggtaa
    13861 gcccctaaaa aatgagggta atccatcaca aagctaatgg ttacgattta atttgacaaa
    13921 acctagaaaa acattataat tgtcttataa caataagtca agaactgaaa atggttcagc
    13981 tctaagacat gacaaggagg agattttatg ttaggaccat ttatctttat tgcttttggg
    14041 gttattataa tcctagctat tgttgccagt accctttatg ttgttcgtca acaatctgtt
    14101 gccatcgtgg aacgttttgg taggtaccaa aaaacagcca ctagtggtat tcatgtccgc
    14161 cttccgtttg ggattgacaa aattgctgcg cgtgtgcagc tgcgtctttt acagtcagaa
    14221 atcatcgttg aaaccaaaac caaggacaat gtgtttgtaa ctttgaatgt tgccactcag
    14281 tatcgtgtta acgaacaaaa tgtaacagat gcttactaca aattaatgaa acctgaatct
    14341 caaatcaagt cttatattga agatgccttg cggtcatccg tgccgaagtt gaccttagac
    14401 gaattgtttg agaaaaaaga tgaaattgcc ttggaagtac aacatcaagt ggcagaagaa
    14461 atgtcaacct atggatatat tattgtcaaa accttgatta ccaaggtgga gcctgatgct
    14521 gaagtcaaac agtcaatgaa tgaaatcaat gcggctcaac gcaaacgtgt agctgctcaa
    14581 gagttggcaa acgcagataa aattaaaatt gtgacagcag cagaagcaga ggctgaaaaa
    14641 gatcgcttgc acggggtagg gattgcccaa cagcgtaagg ccattgtgga tggtttggcg
    14701 gagtctattc aagagcttaa agaagcgaat atttccttaa acgaagaaca aatcatgtcc
    14761 attttgttga ccaaccaata cctggatacc ctcaatacct ttgcggcaaa aggaaaccaa
    14821 accctttttc taccaaatac accgagtggg gtagaggata tccgtacaca agttttatct
    14881 gcccttaaaa caaaataacg tgtaaaagct tggctaaaaa gttgctcaat actggattta
    14941 gcagaaggct atcatacctt gtgaagtggc aaacgacgaa atgaatacat tacttttatt
    15001 ggagaaatga aagtaaaaaa agcctttttc atgattaaca acatagtatt gattaaatgt
    15061 taagttgtat tgacttttaa attaaataag tttaaaatca acttaataag caaaaaggag
    15121 attttcaatg aaatccaaaa aagttgttag tgttatatca cttaccttat cccttttttt
    15181 ggtgacaggt tgtgctaaag ttgataacaa caaatcagtt aatcgtaagc ctgctactaa
    15241 acaaacctat aatagctata gtgatgacca attaagatcg cgtgaaaata ccatgtctgt
    15301 tttatggtac cagcgagctg cggaaactca agcgctttat ttacaggggt atcagttagc
    15361 aacggatcgc ttaaaagaac aactcaataa accaacggat aaaccttatt caattgtatt
    15421 agatattgac gaaacagttc ttgataatag cccttatcaa gctaaaaatg ttttggaagg
    15481 aacaggattt acacctgaaa gctgggatta ttgggtacaa aagaaagaag caaaaccggt
    15541 tgctggtgct aaagactttt tgcaatttgc agaccaaaat ggtgttcaaa tttactacat
    15601 ttcagacaga tcaactactc aagtagatgc tacaatggaa aatctccaaa atgaaggtat
    15661 tccagtacaa ggtcgtgatc atcttctatt cttagaaaaa ggcgtaaaat caaaggagag
    15721 tcgtcgtcaa aaggtcaaag aaacaactaa tgtaacgatg ctatttggtg ataatcttct
    15781 agattttgct gatttttcaa aaaaatctca agaagataga acagctttat tatcagattt
    15841 gcaagaagag tttggaagac gctttatcat tttccctaat cctatgtatg gttcatggga
    15901 aggtgccatt tataaaggtg aaaagctgga tgtgcttaag caactagagg aacgccgtaa
    15961 aagtttaaaa agctttaaat aaagtaattg aaaaagaggt gcaaaagaaa atgtaacctc
    16021 tttttaagta ctattatttt ctgaaaatag ggttaatgac tgaaaaaaat gttgattttg
    16081 tgaaatgatt attttattat tttcatattt tatctttatg ctaggaattg tggtataatg
    16141 gaggagtata aaaaatatta aggagtctat tcacatggct aaattgactg ttaaagacgt
    16201 tgatttgaaa ggtaaaaaag tcctcgttcg tgttgacttt aatgtgcctt tgaaagacgg
    16261 cgttatcact aacgacaacc gtatcactgc ggctcttcca acaatcaagt atatcatcga
    16321 acaaggtggt cgtgctatcc tcttctctca ccttggacgt gttaaagaag aagctgacaa
    16381 agaaggaaaa tcacttgcac cggtagctgc tgatttagct gctaaacttg gtcaagatgt
    16441 tgtattccca ggtgttactc gtggttcaaa attagaagaa gcaatcaatg ctttggaaga
    16501 tggacaagtt cttttggttg aaaacactcg ttttgaagat gttgacggta agaaagaatc
    16561 taagaatgac gaagaacttg gtaaatactg ggcttcactt ggaaatggaa tcttcgttaa
    16621 cgatgcattt ggtacagcac accgtgctca cgcatcaaac gtaggtattt cagcaaatgt
    16681 tgaaaaagct gtagctggtt tccttcttga aaacgaaatt gcttacatcc aagaagcagt
    16741 tgaaactcca gaacgcccat tcgtagctat tcttggtggc tcaaaagttt ctgataagat
    16801 tggtgttatc gaaaaccttc ttgaaaaagc tgataaagtt cttatcggtg gtggtatgac
    16861 ttacacattc tacaaagctc aaggtatcga aatcggtaac tcacttgtag aagaagacaa
    16921 attggatgtt gctaaagacc tccttgaaaa atcaaatggt aaattgatct tgccagttga
    16981 ctcgaaagaa gcaaacgcat ttgctggtta cactgaagtt cgcgacactg aaggtgaagc
    17041 agtttcagaa ggcttccttg gtcttgacat cggtcctaaa tcaatcgctg agtttgacca
    17101 agcacttact ggtgctaaaa cagttgtttg gaatggtcca atgggtgtct ttgaaaaccc
    17161 tgactttcaa gctggtacaa tcggtgtcat ggacgctatc gttaaacaac caggcgttaa
    17221 atccatcatc ggtggtggtg attccgcagc tgctgctatc aaccttggcc gtgctgacaa
    17281 attctcatgg atcagtaccg gcggaggcgc tagcatggaa cttctcgagg gtaaagtatt
    17341 accaggtttg gcagcattga ctgaaaaata atagccatta taatatatag taaagggcat
    17401 gctgatgcat gtcttttttt agttgatcat gtagagttat tgaactttcc ctaacttcac
    17461 ttatcattta ctagttttta gatatagtgg tatttggctg acactgcaat tttcaaaagt
    17521 ttatgacgat ttcatatcaa ttggtttata aaagatatcc taatcataaa taaaacgttt
    17581 accaaaaggg ttttatggat tgatatgtta aaatagatag tgaagggata ggtatgaaaa
    17641 cgttaagaaa attattatct aattacaagt ttgatattaa aaagtttaaa ttgggaatga
    17701 gaacattgaa aacaggctta tcggtctttt tagttttatt ggtttttcat ttatttggtt
    17761 ggaaagggct ccaaattggt gctctaactg ctgtatttag tttaagagaa gactttgata
    17821 aaagcgtgca ctttggcttt tctagaatta ttggtaatag tataggtggc ctactctcct
    17881 tagtattttt tgcattcaat gagatatttc atcaagcttt ttgggttact ttattaattg
    17941 ttcctatttg taccatgtta tgtatcatgg ttaatgttgc atgtaataat aaatcaggta
    18001 ttattggggc agtggctgct cttttgatta ttacactgtc tattccaaca ggacaaacgt
    18061 ttatttatgt gacttcgcgg gtatttgaaa cattttgtgg cgtctttgta gctattttag
    18121 ttaatactga tgttgaactt attaaaaata aatggtttaa caaaaaacac agtgatgtta
    18181 gttaatataa catatatact tgacaggtta tttttttcag cctataataa ggaagatgaa
    18241 aggagtttgt catgaaagaa aaagaactta gacgctcaat ggctgttttt cctattggaa
    18301 cggtgatgac attaacagat ctctctgcga gacaaattcg ctattatgaa gatcaaggtt
    18361 taattaagcc tgaacgaacg caagggaatc ggcgtatgtt ttccttaaat gacatggacc
    18421 gacttttgga aattaaagat tttttgtctg agggattaaa tattgcagct attaaacgcg
    18481 aatatgtcga gcgtcaaggt aagttaatgc aaaaacaaaa agctctaaca gatgcagatg
    18541 tcagacggat cttacatgat gaaatgctga cacaaagcgg tttttctact ccctcacagc
    18601 atattggtaa ttttcgtatt taagatatga attgtataaa atttaaagga gacctattta
    18661 atggcaataa cagtagctga cattcgtcgt gaagtcaaag aaaaaaatgt aacgtttctt
    18721 cgcttgatgt tcactgatat catgggcgtt atgaaaaatg tggagattcc tgcaactaaa
    18781 gaacagttag acaaagtatt gtctaacaag gttatgtttg atggttcatc tatcgaaggt
    18841 tttgtacgga tcaatgagtc agatatgtac ctttatcccg atttagacac ttggattgtt
    18901 tttccctggg gagatgaaaa tggagcagtt gcaggtttaa tttgtgatat ttatacagca
    18961 gaaggaaagc cttttgcagg agatcctaga ggaaatttaa aaagagccct gaaacacatg
    19021 aacgagatcg gctacaaatc atttaatctt ggaccagaac cagaattttt cctttttaag
    19081 atggatgata aaggtaatcc gacacttgaa gttaacgata atggtggtta ttttgattta
    19141 gcgccaattg acttagcaga caacacgcgc cgtgaaattg tgaatatttt aacgaaaatg
    19201 ggttttgaag tggaagctag tcatcatgaa gtggctgttg gtcaacatga gattgatttt
    19261 aaatatgcag atgttttgaa agcttgtgat aatattcaaa tttttaagct agttgtaaaa
    19321 acgattgccc gtgaacatgg actttatgct actttcatgg ctaaaccaaa atttggaata
    19381 gctggatcag ggatgcactg taacatgtct ttgtttgata accaaggtaa taatgctttt
    19441 tatgatgaag ctgataagcg agggatgcag ttatcagaag atgcttatta tttcttggga
    19501 ggactaatga agcatgctta taactacact gctatcacta accctacagt caattcttat
    19561 aaacgattag ttccaggtta tgaggcacct gtttatgtcg cttgggctgg aagtaatcgt
    19621 tcaccgctta tccgtgttcc agcatcacgt ggtatgggaa cgcgtttgga gttacgttcg
    19681 gttgatccga cagctaatcc ttatttagcc ttggctgttc tcttggaagc tggattagat
    19741 ggtatcatta acaaaattga agctccagaa cccgttgaag ctaacattta taccatgaca
    19801 atggaagaac gaaatgaagc aggcattatt gatttgccat caacgcttca taatgcctta
    19861 aaagctcttc aaaaagatga tgtggtacaa aaggcactag gttaccatat ctacactaat
    19921 ttcttagaag caaaacgaat tgaatggtct tcctatgcaa cttttgtttc tcaatgggaa
    19981 attgaccatt atattcataa ctattagact tatcaggacc tgctcaagtt gagtgggtct
    20041 tttggatgag ctattgtatt tgagctagca agctattatt agctgatcgg acaccaattg
    20101 attttccatt atagaaaact aaaaaccagt ccatgttcta tgaggactgg tttttagttt
    20161 gataattatc tgaactagaa ctgatatatt aaagatatag acagatagta ttaagaaatg
    20221 agtcttattt gattttagtg cttatcaggt gttaagacca tcggaattat aattggttca
    20281 cgctcagtct tttcatacaa gaatggacga agagcattga cgatagcacc gttaactgat
    20341 tggatgctag catccttatt ttttaaagca atacggatag cgttaaagag cacacgttgg
    20401 ctttcgcgga tcaagtcacc tgactcacgc atataaatga aaccacgact cagaatatct
    20461 ggtccagcta aaatcatttg tgtgctaaaa tcaacagttg caacagctaa gacaacacca
    20521 tcttctgaca aatcacggcg gtcccgtaaa acggctgctc caatatcccc gatgccatta
    20581 ccatccacgt agatgtcttg ggcattaaag tgaccagcaa tacgcgcact gtcactggtt
    20641 aaagctagaa cgtctccatt ttccataata aagatatttt cttttggaat accaatatcc
    20701 atcgccagtc ctgcatgaac tttttgcatg cgatactcac catgtactgg catgaaatat
    20761 tttggtttaa ttaaactaag catgagcttt tgttcttgct gccctccatg accagaagta
    20821 tgaatattat tgacttttcc atgaataaca tcaacaccag cttcttggat ggtattgatt
    20881 aatttattga cacttgtggt attaccaggg attggacttg atgagaaaat cacagtatca
    20941 ccaggctgta aagttacttg acgatgagtg ccattagcga tacgagcaag tgctgccata
    21001 gactcacctt gactacctgt acacataatt aaaacttcac tagcatgaag atttttaagt
    21061 tcgcttggct caatgaaggt accttttgga actttaatat agccaagttc aataccgtta
    21121 acaattgcct tttccataga acgaccaaaa acggcaattt tacgtcccgt tttaacagca
    21181 gcttctgcag cctgttgcaa acggtagatg tttgaagcga aggaagcaaa aataatacgc
    21241 ccatgaatac cttcgataat ttttaaaatg gactggccaa caactttttc agagttagta
    21301 aaggttggga tttcagcatt agttgagtct gataataagc aaaggacacc ttcttcacca
    21361 agcgctgcca tacgttgtaa atctgcagga tctcctactg gcgtgaagtc aaatttaaaa
    21421 tcaccagtac agataatctt accttgagga gtgtggataa caataccgac cggttctgga
    21481 atggaatgag tagtcttgaa gaaagtgacg ctcatgtttt taaaagttaa ctcggtgttg
    21541 tgattgattt cgtaaacagt tgcttcacgc caaagaccat gttcttccaa tttaccacgg
    21601 ataagagcaa gtgctaaagg tcctgcgtag atagggatat tagcctgttt gagaagaaat
    21661 ggaataccac caatgtggtc ttcgtgacca tgtgtaataa caagagcttt gacccggtct
    21721 aagttatcga caatgtaaga atagtctgga ataacgtaat caattcccaa aagatcatct
    21781 tctgggaatt tgataccggc atcaacgata atgatctcgt cttgatactc aataccataa
    21841 gtattcttcc caatctctcc cagaccacca atggcaaaca ccccaacttc attaggtttt
    21901 aaactgatat ttgtcatctt agaactccgt taattcaaaa acaccggtct ctttttcgta
    21961 atcgaggtgt ttgtcagaaa gtagctcgat aaattccacg ttataatagg tgttatcttc
    22021 aacgagacga cgagccttga tacggccatc gagttcatca gtagcatcaa tattaagata
    22081 gagtgcttta gtactttcac gacgtgggct ttgatccttt gtttcttgat agaaaacttt
    22141 ataaatcatt tgttttttat tcctttcgtt atgaatcaat tatccaaaca ataataaata
    22201 ggtcaaaagg taggtgttcc attttgacgg ttttatatgt tgtcattatt gtgtagtaga
    22261 ttaattcctg attctgtgca attattataa ttataccata aacttagctt ttagtaaaaa
    22321 atttaggtac atttatggta tagtctaaat caaattaaga gtcagccttt ttgtttatga
    22381 ttcttaattt gtgttataat tgatactaga acttgcagta gaaaggcata aaatgaagac
    22441 acttgcattt gatacctcaa ataaaacctt gtcccttgct atacttgatg atgagatact
    22501 tctagcagat atgatcctta acattcagaa aaatcatagt gttagcctta tgcctgctat
    22561 tgattttttg atgactagta ctgatcttaa acctcaagat ttagaaagaa tagtggttgc
    22621 aaaaggccct ggatcttaca caggtttacg agtggcagtt gctactgcaa aaacgttagc
    22681 gtacagttta aatattgcat tggtcgggat ttcgagtcta tatgctttgg ctgcgtctac
    22741 ttgtaaacag tatccaaata ctttggtggt gccattgatt gatgctagaa ggcaaaatgc
    22801 gtatgtaggt tattatcggc aaggaaaatc agtgatgcca caagcccatg cttcactaga
    22861 agttattata gaacaattag tagaagaagg acagctgatt tttgttgggg agactgctcc
    22921 ttttactgag aaaattcaaa agaaactacc tcaggcgata ctacttccaa cccttccttc
    22981 tgcttacgaa tgtggtcttt tggggcaaag tttggcacca gaaaatgtag acgcctttgt
    23041 ccctcaatat ctcaagagag tggaagctga agaaaactgg ctcaaagata atgagataaa
    23101 agatgatagt cactacgtta agcgaatcta atatgaaaac agttgaagaa caagcaaaaa
    23161 atatttatca gcttttggaa atggtttatg gcacgtctcc ttggacttta gaacaagtat
    23221 taatcgatat acggcgggat caaacagatt atttcctact atatgatcgt gataaattgc
    23281 taggtttttt agctattcaa gatttagctg gtgaagttga aatgactcaa attgctatac
    23341 tacctagtca tcaagaactt gggctagcgt ctcaattgat gacgcattta gatagcattg
    23401 aaagtgacat ctttttagag gttagagaat ctaatcatag agcacagggt ttatatcaga
    23461 agtttggttt taaatttatt ggcaaaagac cagactacta tagaaatcct atagaaacag
    23521 ctttattgat gaaacgggaa ggaaaacatg acagataggt atattttagc agttgagagt
    23581 tcttgtgatg agaccagtgt agcgatttta aaaaacgaaa gtaccctctt aagtaatgtc
    23641 attgcaagtc aggttgagag ccacaaacgc tttggtggtg tggtgccaga agtagctagt
    23701 agacaccatg tcgaagtgat tacgacttgc tttgaggatg ctttgcaaga agctggcatc
    23761 agtgcttcag atttatcagc agttgcggta acttatggcc ctggacttgt tggagccttg
    23821 ttagttggat tagcagctgc gaaggctttt gcttgggcaa atcatttacc tttgattccg
    23881 gttaatcata tggcaggtca cttaatggca gcgcgtgaac aaaagccttt agtttatcct
    23941 ttaatagcac tgttggtttc aggaggacac acagaattgg tttatatccc agagccaggg
    24001 gattatcata ttattggcga gacgcgtgac gacgctgttg gtgaggctta tgataaagtt
    24061 gggcgtgtga tgggcttaac ctatccggca ggacgtgaaa ttgaccagtt ggctcataaa
    24121 ggtcaagata cttatcattt ccctcgtgct atgataacag aagaccactt agaattttct
    24181 ttttcaggac tcaagtccgc ttttatcaat cttcatcata atgctaagca aaaaggcgat
    24241 gaactgattc tagaagattt gtgtgcatct tttcaagcag ctgttctaga tattttattg
    24301 gccaaaacaa aaaaagctct gagcagatac cctgcaaaga tgcttgtagt ggctggtggt
    24361 gtagcggcaa atcaaggatt acgagataga ttagcacaag aaattacaca tatagaagtt
    24421 gtgattccta aactaagact ctgtggagat aacgcgggta tgattgcttt agcagcagct
    24481 attgagtatg acaaacagca ttttgctaat atgagcctaa acgcgaagcc tagtttagct
    24541 tttgaccagt ttccagacag ttttgtaata aactagtcac acttgctagt tagtaagatt
    24601 tataatggat aagaatctcc ctttgaaaaa acaacccggt atcttggcat accgggttgt
    24661 catgatgata agtaattggc ttctatggtt actaataatt cagataatta cctgcaaaat
    24721 aattgtctgc ctaaggtgaa gtaagcttac cagctagctt tagtgacgcc aggaagctgt
    24781 cctttgtgag ctaagtcacg gaaattgata cggctaacac caaacttacg catgtaagca
    24841 tgaggacggc cgtcaatttt gtcgcggttc ttcaagcggt ttggatttga atcacgaggc
    24901 aatttgcgca gtgattcata atcgcccttc gcttttaagt cacgacgaag gtcagcgtac
    24961 tgttcaatca gttggagctg cttttggtat ttagcaattt ttgacttttt tgccattgct
    25021 ttctccttct taatatttaa taacctcaga gtcgttatca gcgctctgaa tcaacttaac
    25081 tggtatttaa ctggttaagt ggatatataa tcattataca ataaataaaa gcaaaagcaa
    25141 ataaaaaaat taactagtta tcttttttag ccataatatg aaaaaactcc acatctaagt
    25201 gtgggagtca ggtattaata actgtttaaa ggtgtttaat gagtgtcgct ttggcaactt
    25261 tgagattgaa cttttaagtc aaataaatca gcaggaacgt agtgtttggt tgagaccaag
    25321 atgtctttac cattgtagag agtttcttgg attaaaataa aagcactatt ttctgataga
    25381 gtatacttag ttgctgtgta attgccagtc ttggtatagc cgatttgatt gcaggaatga
    25441 gaagctttac cagattcata gattttctct tctaagaaag taagaagggg ctcttcttga
    25501 ttgagattta tagcatattt agaaataacc tcaataggga taaaagataa actataagca
    25561 atagctttat tttggctatg ataccagcga tcaacaataa tcacaacagg agtttcttgt
    25621 tttagggatg ctgtaatggc aacagtgggc acttcaatcc gatattccaa ttcaaccttt
    25681 gtgatgtcag atgataggct tgcatatatg gggtgttgaa gatattcgaa accttggtga
    25741 tatttagttt caggagtctt gagtataaaa tttccctttc ctctgatatt ttttatgaga
    25801 tgatcctctt ggaggagggc tagggattta cgtagtgtca tccgactgac attgagctgt
    25861 ctagcaagtt caggttctga tggcagttgc atgccaggac tatatgtacc atcttgaata
    25921 agttgaaaaa tagtattata tacttgcaca tgtttaagtt ttttgagttt tttggttaag
    25981 tcgttagtag acatatcact tacctcatta ataatcttta gtggagttta acttgtctaa
    26041 aaactatttt agcactaaca gtattccttg attagaattg tacccatcta tagtgttagt
    26101 atctcacact caggtacttt ttgtcaaaaa agagatgaaa aacaccttaa aaaagcgttt
    26161 acaaaataga gtgtgtgtga tactatacaa gtgtatcaaa aattagacaa gtaaaataca
    26221 ggaggttttt aacatgcaaa attattcagg tgaagtcgga ttgcaatatc acctacagat
    26281 tcgtccaggt gatgtaggtc gttatgttat catgccaggt gatccaaaac gttgtgcaaa
    26341 aattgcagaa cattttgata atgcagttct tgtagcagac agccgtgaat atgttacgta
    26401 tacaggtaca ttaaacggtg aaaaagttag tgttacttca actggtattg gtggtccatc
    26461 agcgtctatt gcgatggaag aattgaaact ttgtggcgct gataccttta tccgtgttgg
    26521 aacatgtggt ggtattgacc ttgatgttaa aggcggagac atcgttattg caactggagc
    26581 tatccgtatg gaaggtacca gtaaagaata tgctccgatt gaatttcctg ctgtagctga
    26641 cttggaagtg acaaatgctc tagttaatgc agctaaaaag cttggttata caagtcacgc
    26701 aggagtagtt caatgtaaag atgcatttta cgggcaacat gagccagaac gtatgccagt
    26761 tagttatgaa ttattaaata aatgggaagc atggaaacgt ctgggaacaa aagcgtctga
    26821 aatggaatct gcagctcttt ttgtagcagc aagtcatcta ggagttcgtt gtggatcaga
    26881 tttccttgtt gttggtaatc aagaacgcaa cgctttgggt atggataacc caatggctca
    26941 tgatacagaa gcagctattc aagttgctgt tgaagcactc cgcacactta ttgaaaatga
    27001 taaatcacaa taagcgaggt tttggaagtc atcatgcaat ttatttatag tattattggt
    27061 attttattgg tattaggaat tgtgtatgca atttctttca atcgtaagag tgtttctcta
    27121 agtttaattg gaaaagctct tatcgttcaa ttcattattg cgctaatctt agtacgtatc
    27181 ccactaggcc aacaaattgt tagtgttgtt tcaactggag ttactagcgt aatcaactgt
    27241 ggtcaagctg gtttaaattt tgtgtttggg tcattagcag atagtggcgc aaaaactggt
    27301 tttattttcg ctattcaaac gcttggtaat attgttttct tatctgccct agttagtcta
    27361 ctttattatg taggaatcct tggatttgta gtaaaatgga taggtaaggg cgttggtaaa
    27421 attatgaaat cctcagaggt tgagagtttt gttgctgtag ctaatatgtt tcttggtcaa
    27481 acagacagtc caatcttggt tagcaaatac ctaggtcgta tgactgatag tgagataatg
    27541 gttgtgttgg tatcaggtat gggaagtatg tcagtttcta ttcttggtgg ctatattgca
    27601 ttaggcattc caatggaata tctcttgatt gcttcaacaa tggttcctat tggcagtatt
    27661 ctcattgcta aaatcttatt gcctcaaaca gaacctgttc aaaaaattga tgacattaag
    27721 atggataata aaggtaataa cgccaatgtg attgatgcaa tcgctgaggg tgcaagcaca
    27781 ggtgcacaaa tggctttctc aattggtgct agtttgattg cctttgttgg tttagtttct
    27841 ttgattaata tgatgttaag tggattggga atccgcttag aacaaatctt ttcatatgtt
    27901 tttgctccat ttggttttct tatgggattt gaccacaaaa acattcttct agaaggaaac
    27961 cttcttggaa gtaagttgat tttaaatgag tttgtttcgt tccaacaatt gggtcaccta
    28021 atcaaatctt tagattatcg tacagcattg gtagcaacta tttcactctg tggttttgct
    28081 aatttatcaa gtttaggtat ttgtgtttca ggtattgctg ttctttgccc ggagaaacgt
    28141 agcaccctag ctcgacttgt tttccgtgca atgattggtg gtattgctgt aagtatgctt
    28201 agcgccttta tcgtcggtat tgtaactcta ttctaaacgt tgacaaaaga aagaaggata
    28261 gtaacgtgga agtaaaagat attttaaaaa cggtagacca tactttgcta gcaacaacag
    28321 caacgtggcc agaaatccaa acaattttag atgatgccat ggcttatgaa acagcttcag
    28381 catgtattcc agcctcttac gtcaaaaaag cagcagaata cgtttcaggt aaattagcta
    28441 tttgtactgt tattgggttc ccaaatggct atagtacaac tgcggcgaag gtttttgaat
    28501 gtcaagatgc tattcaaaat ggtgctgatg aaattgacat ggtcattaat ttgacagacg
    28561 ttaaaaatgg ggattttgat actgttgaag aagaaattcg tcaaatcaaa gccgcatgtc
    28621 aagaccatat cttaaaagtt atcgttgaga catgtcaatt aactaaagaa gaacttatcg
    28681 aactttgtgg agttgtcaca cgttcaggtg cagactttat taaaacctct actggttttt
    28741 cgacagcagg tgctacattt gaagatgttg aagtgatggc aaaatatgtt ggcgaaggtg
    28801 ttaaaattaa ggcagcaggt ggaatctcat cattggaaga tgctaaaaca tttattgctt
    28861 taggagcttc acgcttgggt actagccgta tcatcaagat tgttaagaac gaagctacaa
    28921 aaaccgatag ctattaactt aatcataccg atttagcttg agactaaaac aaaaaactca
    28981 tataatagga gttaaaaagc ctactatctt agtgataata ggctttttta gctatgaaga
    29041 cttccctgcg atccatcctg aacaaagagc tgaggtaata ttaaaccctc cggtgtgagc
    29101 attaatatct aagacctctc cagcgaaata caggccagga actttcttgc tttccaaggt
    29161 tttagggttg atttctttta aatctacgcc tcctttggtc acaaatgatt tagccaaaga
    29221 catttttcct gtaatgggta tctggaggtg tttgagttta tcaagcaatt ccttttcttg
    29281 ttttggagag agttgtttga ccttttcggg gtaatcttct gataaaaaat cagctactcg
    29341 ttcaggcagt aggcctttaa gagcattttt gatgttttta tcacgttgat cactcagata
    29401 agcgattaag tcatctgttg ataagtgtgg caaaaagtcc agctctgcaa tttccccacc
    29461 tttcacaaaa gaggacagac gaagagctgc agggcctgaa aggccaaagt gggtgaagag
    29521 taagtcgtgt gtgatgacgt gtttgtcata actaagagta acgtcgtcta gggaaatacc
    29581 ttgcaagact ttgtgaggaa aatcagttaa cagagggctc tcagcagctt ctaaatcagt
    29641 tacggtcagt ttaaaatgcc gtgcaatatc atgtccaaaa cctgttgaac ccgttgaagg
    29701 gtaggacttg cctcctgtgg ccacaatcaa tttttggcag gtaaaagtct ggtctgcaga
    29761 tttgaggtag aagaggtcat cttgtttttt aacggaaacc atttcagtgc tggttagcac
    29821 ctgaccccca agagctttga tttttttctc cagagcatca atgattgtcc ttgatttatc
    29881 tgttgtgggg aacatccgtc catggtcttc ttctttgagt ttgacgccgt tttcctcgaa
    29941 aaaggcaatg atgtcatggt tgtcaaactg ggaaaaaaca ctatataaaa agcggccatt
    30001 tccaggaatg ccagccataa ggtcatcaag gttaccacta ttagtgacat tacagcgtcc
    30061 accaccggtt cccgctaatt ttttacctaa gcggcgattt ttttcaatta agagagtttt
    30121 atagccatag tagctgctgg agatggcggc catcatacca gcagggccac ctccaataat
    30181 aatcgtatcg tattgagtca tagccttatt ttagcataaa agcgggggat ttaatagtca
    30241 ggtaaatgaa ctaacatggc ataccgtttt ttacgcattt aaacaatgcc tccatgacat
    30301 caaaaagcta gaaaaatagt ccagatgatt aaaattatct ttgtatgaaa acggttgctt
    30361 ttttatttaa ttcatgctat tatattacta aagaatgaag taatcattaa gttattttgt
    30421 aattttttaa aaattaaata attttattaa aggagaatag tatgaaaaaa agatttaata
    30481 gcaaagcgat aactttgctt gctgtaagct ctttaagttt gggatttacg gccgtaacta
    30541 gtgttgtcag tgcggcaaca gcacatccag ctccatctcc aattattgat gaatggaatt
    30601 atggagtaag tgacaactat ggttattcta attattatgt taaatctcca aacaatattg
    30661 gttcaaaatc ttcgataact aattattggg gatccattaa ggcatctgat tctcaaaaat
    30721 acgggtgggc actgtcaagt tcaaaaaaag cttggaatga tattcggttg aatgcacatt
    30781 ggaattactt taatttttag aaatggtata tgcaagctaa agacccaata attattatag
    30841 ggtcttttat aatataggaa gttgtttatg aaattaaaat tatctgtcat tggattattc
    30901 ttttgcttaa ttgctgcgat aggtgttatc agtattagtg atactcaaaa accggtacct
    30961 ttaccaattg atggtgcctt ttcaatccaa ggaaaaagta gcctttctag tgacgaagtt
    31021 tacaaaaaga ttagtaatct atcaaaaatg aaaaacgtta atatttacaa gcctatagtt
    31081 cgtaactcag gtcagttgac ttatatcaat tttaaaaata caaattatga acaattaaaa
    31141 tctgcaccga taacaggcat gtattatacc ttaggtaaaa tagattcaag tagcttaaag
    31201 gtacttacag cttcaggttt gaaacttgtt tatgcagcct atccttggta tatagggggg
    31261 attttacaat ttgatgggac tttaaggttg ttattgatgc tatcaattta cttaacatta
    31321 ttagttgttt tatttgttgt tagaacgagg cagattaaag aaggagtgat aagacattct
    31381 ttaggattgc ctatatataa cttaagaaga gattatgtca tttcttttac ttttgaattg
    31441 gttatggctg gtttattaat gattgcctac agctattttt ggggaagtgg cctctttact
    31501 tacagttcta agttattttt ctctctaatt ttaactaatc ttataatatt ccagattgtt
    31561 gacattatca ctt
//
LOCUS       DATTYN010000021        30392 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.21, whole genome shotgun sequence.
ACCESSION   DATTYN010000021 DATTYN010000000
VERSION     DATTYN010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30392
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.21"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..281
                     /locus_tag="VB649_001197"
     CDS             <1..281
                     /locus_tag="VB649_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEP1670150.1"
                     /translation="LNQAPGDAEEINHFCSLTYHTTFPRFAKIKVNGKDADPLFAWLK
                     EEKSGPLGKRIEWNFTKFLIDQNGQVIKRYSSKTDPKLIEEDLKALLG"
     gene            complement(327..710)
                     /locus_tag="VB649_001198"
     CDS             complement(327..710)
                     /locus_tag="VB649_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HEP1670151.1"
                     /translation="MNKRFKTGFLALVAMLLVACSQGTKQTQTPSVPKADHHVRLVVK
                     EDTNTIDEKVSFGKGDTVLEVLKDNYEVKEKDGFITAIDGIEQDTKANKYWLFKVNGK
                     MADKGADQITVKDGDSIEFYQEVFK"
     gene            complement(694..1197)
                     /locus_tag="VB649_001199"
     CDS             complement(694..1197)
                     /locus_tag="VB649_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEP1670152.1"
                     /translation="MSAKLMSRIAIMSALCVVLRMVFSSLPNVQPVTAFLLSYLLYFG
                     LAEAVLVMMLCLFLSAFLLGFGPWVFWQVTCFVLVLLLWRFALYPLSQQFPKYQLGCQ
                     AFLAALCGLLYGVLIDTCFAYLYSMPWWSYVLAGMPFNIAHALSTLVFFPVVMMLFRR
                     LIGEQKI"
     gene            1522..2370
                     /locus_tag="VB649_001200"
     CDS             1522..2370
                     /locus_tag="VB649_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEP1670153.1"
                     /translation="MRRKIKPIVVLVFFILLAMVLIIGKRQANHAKQKEVEDAKSHIP
                     IATSNPSKAKTSTSETEDFILNPIVDVSGWQLPEEIDYDTLSRHISGAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKTHIKEFQKRNVPVAVYSYALGRSTKEMKEEARAFYKNAAPY
                     NPTYYWIDVEEATMKDMNKGVTAFREELKKLGAENVGLYIGTYFMAEQDISTKGFDAV
                     WIPTYGSDSGYYEAAPNTTLDYDLHQYTSQGYLSGFNNALDLNQIAVTKDTKKTFEKL
                     FGNSNN"
     regulatory      2498..2594
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            2639..3202
                     /gene="thiT"
                     /locus_tag="VB649_001201"
     CDS             2639..3202
                     /gene="thiT"
                     /locus_tag="VB649_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEP1670154.1"
                     /translation="MSPNTNVKYLIEAAIFAALAMALSFIPDFAGWFSPSYGAIALVI
                     FSLRRGLKYGMLAGLIWGLLHFVLGKVYYLSMSQVFIEYILAFTSMGLAGSFSDSLIK
                     TLRRQQTFFAVFLAIMASLLAVTVRYLWHFLAGIIFWGSYAPKGMSAVWYSFSVNGTA
                     GVLTFLITCLALMIALPIHPQLFDPKD"
     gene            3292..3771
                     /locus_tag="VB649_001202"
     CDS             3292..3771
                     /locus_tag="VB649_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEP1670155.1"
                     /translation="MAKKTKLKKTLVEQILDKANIAHQGLKLNALEGDFPDDLQPSDI
                     YKTLALTGDQTGPLIGIIPLTEHLSEKQLAKVSGNKKVSMVPQKDLQKTTGYIHGANN
                     PVGIRQKHSYPIFIDQTALEKGQIIVSAGEVGRSIKISSQALADFVGASFADLKKRK"
     gene            4112..4735
                     /locus_tag="VB649_001203"
     CDS             4112..4735
                     /locus_tag="VB649_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEP1670156.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGAGGDSPLLEKAKDEIHLLGKELA
                     KVAFDAVYTSDLQRAMATAAIILDAFDQQPKLYHTDQLREWRLGKLEGAKIATIAAIY
                     PQQMLAFRENLAQFKPDQFEAESIYQTTQRVCHLIQSFKDKHYQNVLIVGHGANLTAT
                     IRSLLGFEPALLLAKGGLDNASLTILETKDYLTYDCLIWNDKSFLEV"
     gene            complement(4843..5745)
                     /locus_tag="VB649_001204"
     CDS             complement(4843..5745)
                     /locus_tag="VB649_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEP1670157.1"
                     /translation="MITAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSVMNQAYIRFR
                     HYSDVGFPRVMAGEWTTEYFRFWRCKETLLEFGYREIDEAAGVHFQEVYEHELENITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLKKVRKLGLYDYIDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPQTTLYVGDSYDNDIMGAFNGGWHSMWFNHRGRQLKPGTKPVY
                     DVAIDNFEQLFGAVKVLFDLPDNKFIFDVNDKKNPILQMGINNGLMMAAERLLESNMS
                     IDKVVILLRLTKQQEKVLRLKYAR"
     gene            5919..7412
                     /gene="lysS"
                     /locus_tag="VB649_001205"
     CDS             5919..7412
                     /gene="lysS"
                     /locus_tag="VB649_001205"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEP1670158.1"
                     /translation="MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAEL
                     KEKYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGED
                     NYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFV
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVD
                     FWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVS
                     PLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            7548..7688
                     /locus_tag="VB649_001206"
     CDS             7548..7688
                     /locus_tag="VB649_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670159.1"
                     /translation="MTKEYISYISAAIFLLYGLLAAKWIFLGLGLILVLVGLADRLNS
                     KK"
     gene            complement(7785..7997)
                     /locus_tag="VB649_001207"
     CDS             complement(7785..7997)
                     /locus_tag="VB649_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEP1670160.1"
                     /translation="MAEFTFNIEEHLLTLSENDKGWTKELNRVSFNGAEAKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRK"
     gene            complement(8207..9493)
                     /locus_tag="VB649_001208"
     CDS             complement(8207..9493)
                     /locus_tag="VB649_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEP1670161.1"
                     /translation="MSHMKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHARGAKVYVAANMVTHEGNEIGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKAMGLTRVVLAREVNMAELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGGERRSL
                     KGEIPEDYSMSSVDMCMIDHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     IESPEAFYAIKEELIDELWKVAQRELATGFYYGIPTENEQLFGARRKIPQYKFVGEVV
                     AFDSASMTATIRQRNVIMEGDRIECYGPGFRHFETVVKDLHDADGQKIDRAPNPMELL
                     TISLPREVKPGDMIRACKEGLVNLYQKDGTSKTVRT"
     gene            complement(9595..10521)
                     /locus_tag="VB649_001209"
     CDS             complement(9595..10521)
                     /locus_tag="VB649_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEP1670162.1"
                     /translation="MEKIIITATAESIEQVKALLAAGVDRIYVGEANYGLRLPHNFSY
                     DELRQITKLVHDAGKELTVACNALMHQDMMDQIKPFLDLMIEIAVDYLVVGDAGVFYV
                     NKRDGYNFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSAELFTLAENLEFPAE
                     VLVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDASSHYSIYEDNHGTH
                     IFINNDIDMMSKLGELYAHGLTHWKLDGIYCPGDDFVAITKLFIQAKTLLEAGQFTQE
                     EAEKLDQAVHAHHPAGRGLDTGFYEFDPKTVK"
     gene            10720..11004
                     /locus_tag="VB649_001210"
     CDS             10720..11004
                     /locus_tag="VB649_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEP1670163.1"
                     /translation="MPAPLKKHNSVEQDDSYQESQSKFRDFQEFNGQSAKLKELVFFA
                     RIASFSLITVLFAFVLLVMNLAPMFAFLFASIISLGITSLLAKVIKSLLM"
     gene            complement(11163..11591)
                     /locus_tag="VB649_001211"
     CDS             complement(11163..11591)
                     /locus_tag="VB649_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEP1670164.1"
                     /translation="MNKSFKNLVIGAVSGVAAAYFLSTEKGKALKNRAEKAYQAYKES
                     PDDYHQFAKEKGSEYSHLARDTFYDVKDKLASGDLTKEDMLDLLKDKTTAFVQKTKET
                     FAEVEAKEKQDDVIIDLNEDDIIIDYTEQEEPVSDTLDKH"
     gene            complement(11584..11991)
                     /locus_tag="VB649_001212"
     CDS             complement(11584..11991)
                     /locus_tag="VB649_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEP1670165.1"
                     /translation="MDLVGISLMIIALAFVALVIFLIIVLKKVSETIDEAKKTISVLT
                     SDVNVTLHQTNDILAKANILVEDVNGKVATIDPLFVAIADLSESLSDLNSQARHFGQK
                     ATNATGNVSKAGKLALVGKVASKVFGKKGEKHE"
     gene            complement(12013..12792)
                     /locus_tag="VB649_001213"
     CDS             complement(12013..12792)
                     /locus_tag="VB649_001213"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEP1670166.1"
                     /translation="MINPIALKYGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSD
                     AIFDFVLIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLL
                     AYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMF
                     IEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMR
                     TDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE"
     gene            complement(12789..13721)
                     /locus_tag="VB649_001214"
     CDS             complement(12789..13721)
                     /locus_tag="VB649_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEP1670167.1"
                     /translation="MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAA
                     KEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ"
     gene            complement(14086..14358)
                     /locus_tag="VB649_001215"
     CDS             complement(14086..14358)
                     /locus_tag="VB649_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEP1670168.1"
                     /translation="METKFYKQRKNRLVAGVIAGLADKYGWDLALARVLAALLIYGTG
                     FGVLLYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNEEEDGWFW"
     gene            complement(14422..14859)
                     /locus_tag="VB649_001216"
     CDS             complement(14422..14859)
                     /locus_tag="VB649_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEP1670169.1"
                     /translation="MTLTNYVQEVSLADFGKPFHHKAYWNKRLKTTGGRFFPKDGHLD
                     FNPRMLEEHGELIFRKIARHELCHYHLYFEGRGYHHKDRDFKDLLAQVNGLRYVPTSS
                     KSKTNHHYSCQTCGQVYQRKRRINLAKYVCGNCHGKLMEKNQS"
     gene            complement(14846..16978)
                     /locus_tag="VB649_001217"
     CDS             complement(14846..16978)
                     /locus_tag="VB649_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEP1670170.1"
                     /translation="MENNNNHNIAEALSVSLHQIEQVLALTAQGNTIPFIARYRKEVT
                     GNLDEVVIKSIIDMDKSLTTLNERKATILAKIEEQGKLTDQLRTSIEATEKLADLEEL
                     YLPYKEKRRTKATIAREAGLFPLARLILQNAQNLETAAEPFVTEGFASPQEALAGAVD
                     ILVEAMSEDAKLRSWTYNEIWQYSRLVSTLKDEQLDEKKVFQIYYDFSDQVSNMQGYR
                     TLALNRGEKLGILKVSFEHNLEKMQRFFRVRFKETNPYIEEVINQTIKKKIVPAMERR
                     VRSELSDAAEDGAIHLFSENLRHLLLVSPLKGKMVLGFDPAFRTGAKLAIVDQTGKLL
                     TTQVIYPVAPASQTKIQAAKETLTQLIETYQIDIIAIGNGTASRESEAFVADVLKDFP
                     NTSYVIVNESGASVYSASELARHEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIG
                     VGQYQHDVSQKKLSENLGFVVDTVVNQVGVNVNTASPSLLAHVSGLNKTISENIVKYR
                     EENGALTSRADIKKVPRLGAKAFEQAAGFLRIPGAKNILDNTGVHPESYPAVKELFKV
                     LGIQDLDDAAKATLAAVQVPQMAETLAIGQETLKDIIADLLKPGRDLRDDFEAPILRQ
                     DILDLKDLEIGQKLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSKTFVNHPSQVVSVG
                     DLVTVWVSKIDLDRHKVNLSLLPPRDTH"
     gene            17212..17367
                     /locus_tag="VB649_001218"
     CDS             17212..17367
                     /locus_tag="VB649_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670171.1"
                     /translation="MAITHKKNDELEKMLAGFASIPSFDKPLEVNTDGKLATKEKTTE
                     QTKPSKP"
     gene            17515..18417
                     /locus_tag="VB649_001219"
     CDS             17515..18417
                     /locus_tag="VB649_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEP1670172.1"
                     /translation="MSLFSNLPPSVLQWFAIFMSIIIEALPFVLLGTILSGCIEVFVT
                     PELVQKYLPKQKCLRILFGTFVGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLILRLVGAALVAITLGVMLAFIVDDNILKDNAQPVHFH
                     DYSHESLPKRIYLALVHAIDEFFDTGRYLVFGTLIASAMQIYVPTRVLTTIGHNPLTA
                     ILIMMLMAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMVKTFKG
                     RFIVQFIGVSVLMIAVYCLLVGVL"
     gene            18417..19232
                     /locus_tag="VB649_001220"
     CDS             18417..19232
                     /locus_tag="VB649_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEP1670173.1"
                     /translation="MIRFLILAGYFELTMYLQLSGKLDQYINVRYSYLAYISMVLSFI
                     LALVQLYTWMKNIKVHSHLTGKIARLTSPFILVFPVLIGLLVPTVTLDSTTVSAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMRQELHKYKGKKPVTITTEN
                     YMEVMELIYLYPDEFLDRDIQYTGFVYNEPGHDNYQFLFRFGIIHCIADSGVYGLLTT
                     GNQTSYPNNTWLTVKGRLHMEYDKNLEQHLPVLQLAEVHQTKEPNNPYVYRVF"
     gene            complement(19331..20755)
                     /locus_tag="VB649_001221"
     CDS             complement(19331..20755)
                     /locus_tag="VB649_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEP1670174.1"
                     /translation="MGIFPKDFLWGGAVAANQVEGAFEADAKGLSVQDVLPNGGLGEW
                     TDSPTSDNLTLEAIDFYHRYKEDIALFAEMGFKVFRTSIAWSRIFPNGDDDQPNEAGL
                     QFYDDLFDELLNYGIEPLVTLSHYETPLHLAKAYNGWTDRRLIGFFERFAQTVMERYK
                     DKVKYWLTFNEVNSILHMPFTSGGIMTEKEKLSLQDLYQAIHHELVASASVTKLAHEI
                     NPDVKVGCMILAMPAYPMTSDPRDILAAHAFENLNLLFSDIHVRGKYPSYIKSYFKEN
                     GIEIVFEDGDKELLAEHTVDFLSFSYYMSVTQAHNPEAYTSGQGNILGGLSNPYLESS
                     EWGWQIDPIGLRLVLNQYYDRYQIPLFIVENGLGAKDQLVQTADGSMTVHDDYRIDYM
                     SQHLVQVAKAIEDGVEVMGYTAWGCIDCVSMSTAQLSKRYGFIYVDRNDDGTGQLTRY
                     KKKSFDWYRQVIQTNGRYLEDNFS"
     gene            complement(20774..22636)
                     /locus_tag="VB649_001222"
     CDS             complement(20774..22636)
                     /locus_tag="VB649_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEP1670175.1"
                     /translation="MTYQETAKAILAAVGGKTNIQRVTHCVTRLRLVLKNDEKVKDQQ
                     VKAISNVIGVMRKNGQYQIILGNDVNNYYQAFLSLGHFDNQDEDHSSKAKGSILERLI
                     ETIAGVITPLIPALLGGGMLKVVGILLPMLGLASADSQTVAFINFFGDAAYYFMPVMI
                     AYSAAARFKVTPVLAATIAGILLHPAFVAMVAEGKPLALFGAPVTPASYGSSVIPILM
                     MVYLMQYIEKWVNRLVPSVMKSFLQPTLIILISGFLALVVVGPLGVIIGQGLSNTMLA
                     IYHVAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGA
                     ASLAVAFKTKQKQTRQVALAAGISALLAGITEPALYGVTLKFKKPLYAAMISGGLVGA
                     FIGFVNIASYTFVVPSIIGLPQYINPSGGANFTNALIAGAVTIVLAFSLTWFMGIDEE
                     SPEQVSVAADMSQVKSGLSTKQTLYAPMTGEMLFLSEVPDETFSSKLLGEGFAILPSE
                     GVVYAPFDGEVITFFPTKHAVALKNTPGVEVLIHVGIDTVELKGQGFEQLVSVGDVVK
                     RGQALLKMDIDFITSKGYSLISPVVVTNSAEQLEIIIQDDKKMVTKEDALLVIL"
     gene            complement(22638..23480)
                     /locus_tag="VB649_001223"
     CDS             complement(22638..23480)
                     /locus_tag="VB649_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEP1670176.1"
                     /translation="MLIKRVLNHNAAISTNHQGLDILLMGKGIAFGKKVGDSIELNAI
                     ETSFILKNSDNMNRFTELFIKVPQEVVACSERIINLGKIKLGKALDEILYINLTDHIH
                     SAIERHEQGMLIHNPLRWEIQRYYPDEYSLGVKALELIERNLGVTLAIDEAAFIAMHF
                     VNASLDTPFKEPHRLTEIVSYIEQKIKTDFKTELDDTSIDYYRFMTHIKLFAQRVLSE
                     MSYDDDDAELLLVVKTKYPKEYRCVLDISEEIKKRYNYHLNSSELLYLTVHVKRLVKH
                     LKET"
     gene            23808..25175
                     /locus_tag="VB649_001224"
     CDS             23808..25175
                     /locus_tag="VB649_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP1670177.1"
                     /translation="MSHHQQTVSKQTIMAIIAIALIGFSGILSETSMNVTFPTLMSVY
                     QLPLNSLQWMTTIYLLAVAIMMTTSATLKKNVRERPLFFMATGLFTFGTILAVLTHSF
                     AIMLLARIFQGIGTGLVMPQMFNIILERVPMHKVGLFMGFAGLIISLAPAFGPTYGGF
                     MISHFSWQWIFICILPVPLIAGILAYYYLEDSPVSEKVPFDWLAFIALSISLTSALLA
                     ITSLENGSVNLYYLGLFILSFVLFLYKNLTAKQPFLDIRILKIPSLTFGLIPFFVFQL
                     INLGINFLTPNFIVMEKIANSSQAGMVLLPGTLLGALLAPAFGKLYDQKGARLSLYLG
                     NALFSLSLIIMTLQTRHFMLLPFTLLYILFTFGRNMGFNNSLATAIRELPAEKNADAT
                     AIFQMMQQFAGALGTAMASLIANSQPEFTSGVQSVYLLFTFFALCNFAFFIAMFKHLA
                     KKGLA"
     gene            complement(25229..26779)
                     /gene="ftsY"
                     /locus_tag="VB649_001225"
     CDS             complement(25229..26779)
                     /gene="ftsY"
                     /locus_tag="VB649_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEP1670178.1"
                     /translation="MGLFDRLFGKKETPKVAEEKLEENLLTETTQKEELSEKANEQDK
                     IEVVQQEDVSSEGAGSVENGPEAASVNAQVEEETGDNSNHSSEDTNEFAADKTDLKVS
                     ELSQSTASEPKDLVDQPVVEQFPTKQAQADASNDSAKEEAVDTLKEQSSSQQVMEDYY
                     RRKAALEKSLQEKAAATVPVMPEEVPQENQASTSAEASQNKATHDTIPETDQEKYKRS
                     LKKTRTGFSARLNSFFANFRRVDEEFFEDLEEMLILSDVGVHVATTLTEELRYEAKLE
                     NAKKPDALKRVIVEKLVDIYEKDGRYNEAINYQDGLTVMLFVGVNGVGKTTSIGKLAY
                     RYKQEGKKVMLVAADTFRAGAVAQLVEWGRRVDVPVITGPEKADPASVVFDGMEKAVA
                     KGVDILLIDTAGRLQNKENLMAELEKMGRIIKRVLPDAPHETLLALDASTGQNALSQA
                     KEFSKITPLTGLILTKIDGTAKGGVVLAIRQELDIPVKFIGFGEKVDDIGEFHSEDFM
                     KGLLEGIL"
     gene            complement(26779..27603)
                     /locus_tag="VB649_001226"
     CDS             complement(26779..27603)
                     /locus_tag="VB649_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEP1670179.1"
                     /translation="MNIRILALDLDGTLYNAEKIVTDANKKALAAAREKGVKVVITTG
                     RPLKAIGNLLEELDLLDHDDYSITFNGGLVQRNTGEVLDKSSLSFDQVCQIQQALEAV
                     GLPTDIISGGDVYSIPSKDGRHSQYHLANPLLTFIEVTSVAELPKYITYNKIVTVTDP
                     DFLDQQIIKLSPSLFEDFEAFKSRDIIFEIMPKGIDKAFGLNLLCQHLGLDARHVMAM
                     GDEANDFAMLEWAGLGVAMANGVSGAKAVADAVTTLTNDESGVAEAVKTFILEEES"
     gene            complement(27607..28404)
                     /locus_tag="VB649_001227"
     CDS             complement(27607..28404)
                     /locus_tag="VB649_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEP1670180.1"
                     /translation="MIKLIATDMDGTFLAEDGTYNQEQLAALLPKLAEKGILFAVSSG
                     RSLLAIDQLFEPFLDQIAVIAENGSVVQYHGEVLFADTMTKEQYTEVAKKVLANPHYV
                     ETGMVFSGQKAAYILKGASEEYIQKTKHYYANVKVINGFEDMENDAIFKVSTNFTGHT
                     VLEGSDWLNQALPYATAVTTGFDSIDIILKEVNKGFGMEHLCQALGIKKAETIAFGDN
                     FNDYQMLEFAGRAIATENARPEIKVISDQVIGHCNDGAVLTYLKGLV"
     gene            28708..29835
                     /locus_tag="VB649_001228"
                     /pseudo
     CDS             28708..29835
                     /locus_tag="VB649_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         9121 a         6475 c         5391 g         9405 t
ORIGIN      
        1 ttttaaatca agctccagga gatgctgagg agattaatca cttttgcagt ctgacctatc
       61 acactacttt ccctcgcttt gcaaaaatca aagtgaatgg taaagacgct gatcctttgt
      121 ttgcctggtt aaaagaagaa aaaagtggtc cccttgggaa acgcatcgaa tggaatttca
      181 ctaaatttct cattgaccaa aatggtcaag tcattaaacg ctattcctca aagacagatc
      241 ctaaactaat tgaagaagac cttaaagcac ttcttggtta atataaaata gacttggcgt
      301 gccaagtcta ttttatatta tagttactat ttaaaaactt cttgataaaa ttcaatgcta
      361 tcaccatctt taacggtaat ttgatcggca cccttatctg ccatctttcc attcacctta
      421 aaaagccagt atttgttagc tttcgtgtct tgctcgatac catcaattgc tgtgataaaa
      481 ccatcttttt ctttgacctc ataattatct ttgagaacct caagcaccgt atctcctttt
      541 ccaaaagaaa ctttttcatc aatggtattg gtatcttctt tgacaactaa gcgaacgtga
      601 tggtctgctt ttggaacgct tggagtctgt gtttgttttg ttccttgcga gcaagcaaca
      661 agtagcatag caacaagcgc tagaaatcct gttttaaatc ttttgttcac cgattaacct
      721 cctaaataac atcatcacaa ctggaaaaaa gacgagagtt gataaagcat gcgctatatt
      781 aaagggcatc ccagctagaa catagctcca ccaaggcata ctatacaaat acgcaaaaca
      841 agtatctatc aacaccccat aaaggaggcc acataaggcg gccaagaaag cctgacagcc
      901 aagctgatat ttggggaatt gctgagacaa agggtacaag gcaaaacgcc ataataaaag
      961 aacaagcaca aaacaagtaa cttgccaaaa gacccaaggg ccaaatccca gcaaaaaggc
     1021 tgataaaaac aagcacaaca tcataactaa tacagcctcg gctaacccaa agtaaagaag
     1081 ataactgagt aaaaatgccg tcacaggctg cacgttaggc aggctgctaa aaaccattct
     1141 caacacaaca catagggctg acatgatagc aatgcgactc ataagcttag ctgacataaa
     1201 cttcttcctc gtttttttct ctattatgac agatttacag agcgtttacc agtttgaagc
     1261 tcacttcttt atcaaatgat aataacatga gaattaaata acaaaacagt acttgctgac
     1321 tgtcatgata tagtcaaaga ctaaactaat attgtaaaga atatagctac caactataag
     1381 agatagtgac ataaacttga catagttaga gaggatctca tttgtaactt ctaaaagata
     1441 ataccttaaa atgcaagaca atataagaaa acagttagga tattttgatt ttttttagta
     1501 attagggtac aataacagtt aatgagaaga aaaataaaac ctattgttgt gctagtcttc
     1561 tttattttac tggcaatggt attgattatc ggaaaaagac aagctaatca tgcgaaacaa
     1621 aaagaagttg aagacgctaa gagtcatatt cctattgcaa ccagtaatcc tagtaaagca
     1681 aaaactagca cttctgaaac cgaagacttt attttaaatc ctattgttga tgtttccggc
     1741 tggcaactcc ctgaagaaat tgattatgac acattgtcac gtcacatctc tggcgcaatt
     1801 gtacgtgtct atggaggatc gcaaattaca gctcataaca acgctgcttt tacaactgga
     1861 attgacaaat cttttaaaac gcatatcaaa gaatttcaaa aacgaaatgt tcctgtagct
     1921 gtttacagtt acgcacttgg tcgtagtact aaagagatga aagaagaggc ccgagctttc
     1981 tacaaaaacg ctgctcccta taatccaact tactactgga ttgatgtcga agaagccact
     2041 atgaaagata tgaataaagg cgtaacagcc ttccgagaag agcttaaaaa acttggtgct
     2101 gaaaatgttg gtctctatat tggaacttat tttatggcag aacaagatat ttcaacaaaa
     2161 ggtttcgatg ctgtatggat tccgacttat ggtagtgatt ctggctatta tgaggctgcc
     2221 cctaatacaa ccttagatta cgatttacac caatatacct cacaaggtta tctcagtggt
     2281 tttaacaatg ctttagattt aaatcaaatt gccgtaacaa aagacactaa aaaaacgttt
     2341 gagaagttat ttggcaactc caacaattaa gaggttagca tcatggctaa tcttttttta
     2401 tagtttacat cttaccaaga aaaactctag gtcaataatt taaaacccct tatccttgac
     2461 aaggagatta tctcatcata taatgaaagc actataatat ttcacaaagg agtgctttgg
     2521 ctgagatcgc aattgcgaaa tcctgaggac ctgatcttgt tagtacaagc gtagggattg
     2581 tgaccaataa tcaatgattg gaaagcgata ctctttttgt gcacaaaagg agttttttat
     2641 gtcaccaaac accaatgtca aataccttat cgaagctgct atttttgctg cattggcgat
     2701 ggccctttca tttattccag attttgctgg ctggtttagt ccttcttatg gtgctattgc
     2761 actggttatt ttctctttgc gccgtgggtt aaagtacggc atgttggcgg gtctcatttg
     2821 ggggctgctt cactttgtac ttggaaaagt ttactatctc agcatgtccc aagtctttat
     2881 tgaatatatc ttagccttta cctctatggg attagccggt agtttctctg atagtttgat
     2941 taaaacttta agaagacaac aaaccttttt tgccgttttt cttgcaataa tggctagttt
     3001 actagccgtt acagtacgtt acttgtggca cttccttgca ggaatcattt tctggggcag
     3061 ttacgcccct aaaggcatgt ccgctgtctg gtattctttt agcgttaatg gtacagctgg
     3121 tgtcctaact tttttaataa catgtttagc gttaatgatt gctttaccaa ttcatcctca
     3181 attatttgat cccaaagact aatttttagt catttgaatc ttacattaaa aaaatggtat
     3241 aataatgttg ttataccatt ttttatgttt agataaaggt aaggacttga tatggctaaa
     3301 aaaacaaaac tcaaaaaaac cttagtagaa caaatcctcg ataaggctaa tattgctcat
     3361 caaggactca agcttaatgc tctagaaggc gactttccag atgatcttca gccatcagat
     3421 atttacaaga cacttgctct gactggtgat caaacaggtc ctctaattgg cattattcca
     3481 ttaacagaac acttatcaga aaaacaattg gcaaaagtat caggtaacaa aaaagtgtcc
     3541 atggttcctc aaaaagactt gcaaaagaca acgggctata ttcacggtgc caataatcct
     3601 gttgggattc gtcaaaaaca ttcatatcct atttttattg accaaactgc actggaaaaa
     3661 ggtcaaataa tcgtttcagc tggtgaagtt gggcgttcta taaagatttc tagccaggct
     3721 ctagctgatt tcgttggcgc aagctttgct gatttaaaga agagaaaatg aacactactg
     3781 ccaactttat ctggtttctt ttttaagttt ttcgccttga ttaagctagt ctttgtttag
     3841 tattattttg atctcaactg ctttaacatt gatcctgtta atctttttct tttgtaaagg
     3901 cttgatatca cgacaaattc aggtcgattt gtcttaaatc taatatgggc tttacacttt
     3961 aatcagaacc tagctattat acacttatac tacgcttttt tactttatct tttcactata
     4021 ggtattattt ttgcttggtg atgcctaaac tttttctggt tactttttta tttttagcgc
     4081 tcgcatcagt tatctctaaa aggaggctta aatgaaatta tattttgtaa gacatgggaa
     4141 aaccctttgg aatttagaag gtcgctttca aggcgctggg ggcgattcgc cattacttga
     4201 aaaggcaaaa gacgaaattc acttacttgg caaagagtta gctaaggtgg cttttgatgc
     4261 cgtttatact agcgaccttc aaagagctat ggcaacagca gctattatct tagatgcttt
     4321 tgaccaacag ccaaaacttt accacaccga ccagcttcgg gagtggagat taggtaaatt
     4381 ggaaggggct aaaatagcaa caattgcagc tatatatccc caacaaatgc tggcttttcg
     4441 ggagaatcta gcccagttca aaccagatca gttcgaggct gaatcaattt accaaacgac
     4501 tcaacgtgtc tgccatctta tccaatcgtt taaagataaa cattatcaaa acgttcttat
     4561 tgtaggacac ggcgctaact taacagcaac tattcgctca ttattaggtt ttgaacctgc
     4621 tcttttactc gctaaaggtg gcttagataa tgccagtctt actattcttg aaactaaaga
     4681 ttatttaact tatgactgtt taatttggaa tgataaatct tttctagagg tgtaaaacca
     4741 ctagaaaata ataaaaaaag ctaacacatt gatctcttac tgacaagaca ctcactttgc
     4801 tagctttttt tattattatc tagtgggcta ttatggtttc atctatctgg catattttaa
     4861 gcgcaaaact ttttcttgtt gcttggttaa ccgaagcaag ataaccacct tgtcaatgct
     4921 catgttgctt tcaagtaaac gctctgctgc catcatcaag ccattattga ttcccatctg
     4981 taaaattgga tttttcttgt cattgacatc aaaaataaat ttattatcag gtaaatcaaa
     5041 gagtacttta acggcaccaa agagctgttc aaagttatca atagccacat cataaacagg
     5101 cttagttcct ggttttagct gacgacctct atgattaaac cacatggaat gccaaccacc
     5161 attaaaggca cccatgatat cattgtcata agagtcccca acatatagtg tggtttgtgg
     5221 gttcatgtca aattgttctg ctgccaggtt aaaaatttct ttttctggtt tttgaaagcc
     5281 tgttgcttgg ctcacaatga cacgcttagg atcaatataa tcataaagcc ctaatttacg
     5341 aacttttttc agctgatgtt ctgtgggccc attggtaata atccccatag gaacattctt
     5401 tgattttaaa aagtcaaggg tcatacgcat ctcatctaac atggtaatgt tctcaagttc
     5461 gtgctcatag acttcttgaa aatgtactcc cgcagcttcg tcgatttctc gatagccaaa
     5521 ctcaagcagt gtttccttgc aacgccagaa tcggaaatat tctgtggtcc actcccctgc
     5581 cattactctt gggaatccaa catctgaata gtgacgaaag cgaatataag cttgattcat
     5641 tactgacata tcaaaatctg ggaagcactt ttccatggcg attcgataag gcgcttgctg
     5701 gtcgtaaatt gtgtcatcca catcaaaaac aatagcagta atcatgagtc tcttttcttt
     5761 tctagtttaa tatcccaatc attatactat tttccattag gcttttcaat ttcattttca
     5821 aaaaaatgcc ccgctgcagt cgcattttcc aacgaaatat aggtgtattc tagccccttt
     5881 tatgatacaa tggaaaggaa atcgtattgg aggaaaatat gtctaatcaa cacatcgaag
     5941 aattaaatga ccaacagatt gtccgtcgtg aaaaaatgat ggctctggct gaacaaggaa
     6001 ttgatccttt cggtaaacgc tttgaccgca cagccaattc tgctgaatta aaagaaaagt
     6061 atgctgataa aacaaaagaa gaattacatg agttaaacga aacagctatt gttgctggcc
     6121 gcttgatgac aaaacgtggc aaaggtaagg ttggttttgc tcatcttcaa gaccgtgaag
     6181 gccaaatcca actttatgtt cgcaaggact ctgttggcga agacaactat gaaatcttca
     6241 aaaaagccga tttaggcgac tttatcggcg ttgaaggcga agtcatgcgt acagacatgg
     6301 gcgagttgtc aatcaaggca accaagttga ctcacctttc taaatcactt cgtcctcttc
     6361 ctgaaaaatt ccacggatta actgatattg aaaccattta ccgtaagcgt caccttgatt
     6421 taatttcaaa tcgtgaaagc tttgaccgct tcgtgacccg ttccaaaatg atttcagaaa
     6481 tccgtcgtta tttagacggt cttgatttcc tagaagtaga aacgcctgtg cttcataacg
     6541 aggctggtgg tgctgctgct cgtcctttcg ttactcacca taatgctcaa aacattgata
     6601 tggtgcttcg tatcgcaaca gaacttcatt tgaaacgttt gattgttggt ggtatggaac
     6661 gtgtctatga aattggtcgt atcttccgta acgagggaat ggatgctact cataatcctg
     6721 agttcacttc tattgaggtt taccaagcct atgcagacta tcttgatatc atgaacctga
     6781 cagaaggcat tatccaacat gctgctaaag ctgttaaagg tgatggccct attgattatc
     6841 aaggaactga aatccgtatc aatgaacctt tcaaacgtgt tcacatggta gatgctatca
     6901 aggaagtgac aggtgttgat ttctggcctg aaatgactgt cgaagaagct attgcacttg
     6961 ccaaagaaaa acaggtccca ctcgaaaaac acttcacaag tgtcggacat atcatcaatg
     7021 ctttcttcga ggaatttgtt gaagaaacct tggtccaacc aacctttgtg tttggtcatc
     7081 ctgttgaagt atcgcctttg gctaagaaga atccagaaga tacccgcttc accgaccgct
     7141 tcgaactttt catcatgacc aaagaatacg ccaatgcttt cacagagttg aatgatccca
     7201 ttgaccaatt atctcgtttt gaagcacaag cacaagccaa agaacttggt gatgacgaag
     7261 caactggcat tgactacgac ttcgttgaag ctcttgaata tggtatgccg ccaaccggtg
     7321 gactcggaat cgggattgat cgtctttgca tgttattaac aaacacaaca acaatcagag
     7381 atgtgctttt attcccaacg atgaaacctt aactttttta agatttgtat tcatatctta
     7441 aaaccgataa gtggcaatat aacataacgt tttattatct ctaaccagtc ttcattacca
     7501 tgaagactgg tttattaaca gtagcttata gaaagtgact taacaagatg accaaagaat
     7561 atatctccta cattagtgct gctatcttct tgctttatgg ccttttagct gccaaatgga
     7621 tttttcttgg gctaggctta attttggtac ttgtcggcct tgctgatcgc ctcaattcaa
     7681 aaaaataatc cttctattcg cccctgtcct cttaacctag cgatgtcatc accaggttaa
     7741 aaggacaagg gcaaacgagg gattatgttt cgattaaggt aacattactt acgaaaagcg
     7801 tctaagatgg ttttaaattc ttcattagta agagtaatgc ctttccccat tttcgtatgg
     7861 tctggactcc acgtgcggat atcccatttc gcttctgcac cattaaagct gacgcggttc
     7921 aattcttttg tccaaccttt atcattttct gataaggtga gtaaatgttc ctcaatgttg
     7981 aatgtaaatt ctgccattag ttttcctcct catctatact attcgaaatt aaagtggaaa
     8041 aaatcatctt tttttcactt tttttatgac tcattctcct attattctat caagttttga
     8101 gaaaataagc tattgtgata tccaattttc aaaaaaaaca ggctctcttc tcccaactat
     8161 ggtcgtatac catttggaaa aagagggcct ctagtatttc ttgttactat gttctaacag
     8221 ttttactggt gccatctttt tgatagaggt tgacaagacc ttccttgcaa gccctaatca
     8281 tatcccctgg cttaacttct ctcggtaaag agatggttaa gagttccatt ggatttgggg
     8341 cacggtcaat cttttggcca tccgcatcat gtaagtcctt aacaaccgtt tcaaaatgac
     8401 ggaaacctgg tccataacat tcaatccgat cgccttccat gatgacatta cgctgacgaa
     8461 tggtcgctgt catgctagct gagtcaaagg caactacttc tccgacaaat ttatattgtg
     8521 gaattttgcg gcgagcacca aataattgtt cattttcagt tgggatacca tagtaaaaac
     8581 ctgtagccaa ctcgcgctgg gcaaccttcc acaactcgtc aatcaattcc tctttgatag
     8641 cataaaaagc ttctgggctt tcaatgtaag cgtctacagc cgccttgtaa cagttggtta
     8701 cggttgagac gtagtggata gatttcattc ggccttcaat ttttaagcta tcaaccccat
     8761 tttcaatcag gtcaggaata tggtcaatca tacacatgtc aacagaggac atagaatagt
     8821 cttctggaat ttcccctttt aaggagcggc gctctcctcc aaatggcatg tcatacaaat
     8881 catacttcca gcggcaagac tgtgagcagc cgcccctgtt ggcatcacgg tgactcatgt
     8941 ggtttgacaa aacacagcgg cctgaataag aaatacacat ggctccatgg acaaaggctt
     9001 caatttccac atctgtccgc ttacggattt ctgctaactc ggccatatta acctcacgag
     9061 ctaaaacaac tcgggtcaaa cccatggctt tccaaaattc aaaggtctcg taattggtag
     9121 atgaagcttg cgttgacaaa tgaatttcca aacctggggc ttctgttgaa caaataacaa
     9181 tcaaggctgg atctgaaaca atgaccgcat caagccccat atcacgcagt tgacgaaacc
     9241 actcgcccgc accaatttcg ttcccttcgt gggtgaccat gttagcagca acatagacct
     9301 tagctccacg cgcatgtgca taatcaatgc cttcttgcaa ttcttccata gagaagttac
     9361 cagcgcggct tcttaggcca taggcctgtc ctccaacaaa aacagcatct gcgccataat
     9421 caatcgcaac ttttaatttt tcaagtgttc cagcaggtga taagacctcg ggacgttttt
     9481 tcatatgtga catgtgatat tctttctatt ttcaagatag gtagattacc tgtgtaatgt
     9541 tgtcataacc ctgtcttgcc ctgaaatagt aaactcactc aagacaagga ttacttattt
     9601 aacggttttt ggatcgaact cataaaagcc agtatctaat ccacgaccag ctggatgatg
     9661 ggcatgcact gcttgatcaa gcttttcagc ttcttcttgg gtaaattgcc cagcttctaa
     9721 taaggtttta gcctgaataa acaatttagt aatagcgaca aaatcatcac ctggacagta
     9781 aatgccatct agcttccaat gagttaagcc atgcgcatac agctcaccca atttagacat
     9841 catgtcaata tcattattaa tgaaaatatg agtgccatga ttgtcttcat aaatggaata
     9901 atggctgcta gcatctcctg gttctgccaa gaaaagtcct cgttcacgac taacctcatc
     9961 atcaatcttt gtaaaatggt aataattttc tagcaaggga cgtttcgagt gatgaatcac
    10021 cgaggcgccg taaactagca cctctgctgg aaattccaaa ttttcagcta aggtgaataa
    10081 ctctgctgat gggatttccc ttgctaaaac actttcaaca gcaccatgtt gcccccagaa
    10141 atttacctga cggctagaag tcacaaaaac agaggtatca taaatcagtt taaagttata
    10201 gccatccctt ttattgacat aaaacacacc tgcatcacca accacaagat aatcaacagc
    10261 aatctctatc attaagtcta aaaagggttt gatctgatcc atcatatctt gatgcatcaa
    10321 agcattgcaa gctactgtca actctttgcc tgcatcatgc actagtttgg taatttgtct
    10381 caattcatca taagaaaaat tatggggaag gcgtaacccg taattggctt caccaacata
    10441 aatacgatca acaccagcag ctaataaagc tttgacttgc tcaatgcttt cagctgtggc
    10501 tgtaataatt attttttcca tataagcttt attataccaa aaattttaag accgtaagca
    10561 tctttcttgc aaaagcccaa gcgttaagct agtcccctta ctgttatagc atgataagtc
    10621 acttgtcatt agtaaatctt ttcaaatctt ttaaaaaaag atgacaagaa gagactttta
    10681 tgatagaatt acttagtatg ttaaggaaag gagaggacta tgcctgcacc gttaaagaag
    10741 cataattcgg ttgaacagga tgattcttac caagaatctc aaagtaaatt tcgagatttt
    10801 caagagttca atggccaaag tgcaaagcta aaagaattag tcttctttgc tcgtatcgct
    10861 agtttcagcc ttattaccgt tttatttgca tttgtcctgc tcgtaatgaa tttagcgcca
    10921 atgtttgctt tcttatttgc aagcatcatc agcttaggca ttacttcctt attagccaag
    10981 gttatcaaat cattactgat gtaacttcca gagtccgttt tacgtgactc tttttttgtg
    11041 tcaaaaacaa aaaaagattg aagctacaat cccccccttc tttagttagc ctaaaactaa
    11101 ccatcaggac tagtgatcag atccttcaac cttttcttct tctatgtttt aggtcatttt
    11161 agttagtgtt tgtctaatgt atcactaaca ggctcctctt gttcagtata gtcaatgatg
    11221 atgtcgtctt catttaaatc aatgataaca tcatcttgct tttctttcgc ttcaacttcg
    11281 gcaaaggttt cttttgtttt ttgcacgaaa gctgttgttt tatctttgag caagtctaac
    11341 atgtcctctt tagttaagtc accagaagcc aacttatctt tcacatcata aaaagtgtca
    11401 cgtgctaaat ggctgtattc actacctttt tctttagcaa attggtggta atcatctgga
    11461 ctttctttgt aggcttgata agctttttca gcacgatttt tcaaagcctt gcctttttct
    11521 gttgataaga agtaagctgc cgctactcct gaaacagctc caatcactaa gtttttgaaa
    11581 cttttattca tgcttttctc ctttttttcc aaatactttt gaggctactt taccaactaa
    11641 tgctaatttt ccagcttttg aaacattacc tgtagcatta gttgcttttt gcccaaaatg
    11701 ccttgcttga ctatttaaat ctgaaagact ttctgacaaa tcagcaatag caacaaacaa
    11761 tggatcgatg gttgctactt taccattaac atcttcaaca aggatattag cttttgctaa
    11821 aatatcatta gtttgatgaa gtgtcacatt aacatcactt gtcaatacag aaatcgtttt
    11881 tttggcttca tcaattgttt ctgagacttt ctttaataca ataatcaaga aaatcaccaa
    11941 agcaacaaat gcgagtgcaa taatcatcag tgagattcca actaagtcca taagtttctc
    12001 ctttttctat ccttattctt gataataaga aattcctttt tgacgacgtc tttttataac
    12061 aaagattaag ccaataataa ttaataaggc agacacatat tgggagatgc gaatacctaa
    12121 aaacataaga ctatctgttc gcataccttc aatgactagt cttccactac cataccaaat
    12181 taagtaaaat gcaaagattt ctccatctaa tagacttttt ggcttacgac gccacatcat
    12241 aataatgaca aatcccaaaa gattccaaag tgattcatag agaaaggtcg gaatgcggta
    12301 acttccctct ataaacattt gcttttgaat aaagcttggt aagtaattta actggctcac
    12361 agctttacca taggcttctt ggttgataaa atttccccag cgaccgatag cttgagcaac
    12421 catgacactt ggtgcggcaa tatctaaaaa atgaatggga ttgagcacct tgttataaca
    12481 gtaagccaaa agtacaagag ctcctgtaat gagaccgcca taaatagcaa taccgccatt
    12541 ccaaatggct atgatttcat ctaaatgctt gacataataa gaccattcaa aaataacata
    12601 gtaaattctt gcaccaacaa tagcaagtgg aaaagcaatc agaacaaaat cgaaaatagc
    12661 gtcagatgat attccttttt tgggtgcttc ttttgatgct aagtaaaccg ccaaaacaag
    12721 tcctgacaag atacatagcg cataccagtg gatggctagt ggaccatatt ttaaggcaat
    12781 gggattgatc attgactcac ctcatttttg gtgattagtt gagttaaacg atcttcaaaa
    12841 gtttttgtag catcaaagcc catttcttta gcccgatgat tcatcgcagc ggcttcaata
    12901 accactgaaa catttcgacc tgtttttacc ggaatacgaa tacgagggat tctcactcct
    12961 gagaaagtta tctcctcatt accgtttccg agacgatcaa aaaccttacc agcctcaaag
    13021 ttttcaaggt aaatggccaa ttgaacttgt gatgagtcct tcacagcact agctccataa
    13081 agcgacatca catcaataat acctacccca cgaatttcaa gcaagtggcg caagatctct
    13141 gctggctctc cccaaagggt ttcttcatct ttggcataga catccacacg gtcatctgca
    13201 accaaacgat gccctcgctt aactaattct aaaccagtct cacttttacc aattccagaa
    13261 tccccttgga taagaacccc cataccataa atatccatta aaacgccgtg aacactagta
    13321 cgttcagcta aagaagcgtc aagaaaataa gacatttctc cagctaagcg gctagttgaa
    13381 acacggctac ttaaaagtga aataccttct tcttttgcag cttgaaccat ttcttttgga
    13441 atggctaaat ttctagagac aaccactgca ggagtgtcct ttttgaacat ctcttttaaa
    13501 acagaataac ggttgtgaga agtcatctgt gtaagataag accactcttt cattccaaat
    13561 agctgcaacc tttctggagc ataataatca aaataaccag tcatttcaag acctggacgt
    13621 gaaatatctg atgttgttat ctcttttgac aacaagttat ctgtagcata aaccacatca
    13681 agtttaactt tttgcactag catctttaca gtaacggtca taatttctcc tttttcaata
    13741 ttataacaca aatcgaccgt tagacccttg caaatactca ttttttcact actaaatgag
    13801 aacaacgaca ccaaaaatgg tcttagctct attaaaaact aggttttatc atttagagat
    13861 atgagtcaaa aataagacaa tggcaaacaa atactttact agtatcattg agcaattagt
    13921 gcttattatg gtatttaaaa aggtatcatc ttactaagtc aaaaagcaaa aagcctcatc
    13981 atagctgata agacccctcg cttacttaca tatcaaaaca ttttattatc atcagttaat
    14041 cacatggttg ctcttacgtg atgaattatc gttttaactg attgtttacc agaaccagcc
    14101 atcttcttct tcatttaaga catcagcgtc tttacgacga cgaggacctc ggccataacg
    14161 ttcttcaagc aagtcttcct tgtaaggtaa gaagatggcc aacaaaatat aaagcaaaac
    14221 tccaaaacca gttccgtaaa taagaagagc cgctaagaca cgcgctagag caagatccca
    14281 accatactta tctgctaaac cagcaatgac acctgcaacc aagcgatttt ttcgctgttt
    14341 atagaattta gtttccacgt ttctttacct cctcattcta tgatactagt ttacattgtt
    14401 tttcgcaaaa taaaaccagt cttacgactg atttttttcc ataagtttcc cgtggcaatt
    14461 tccacaaaca tatttagcca gattgatacg cctttttcgt tgataaacct gcccacaggt
    14521 ttggcaacta taatgatgat tagtctttga tttagagcta gttgggacat aacgaagccc
    14581 gtttacttga gctagcagat ctttgaaatc cctatcttta tgatggtacc ctcttccttc
    14641 aaaataaaga tggtaatggc agagctcatg gcgagcaatt ttccgaaaaa taagctcacc
    14701 gtgctcctca agcatcctag ggttaaaatc caaatgacca tcttttggaa aaaagcgacc
    14761 gccagttgtt tttaggcgct tgttccaata agccttgtgg tgaaatggtt tgccaaaatc
    14821 agccagggaa acttcttgga cataattagt gagtgtcacg cggtggcaat aggctgagat
    14881 tgaccttgtg gcggtccaag tcaatcttag agacccaaac agttaccaag tcacccactg
    14941 aaacaacttg actagggtgg ttgacaaagg ttttgctcat ttcagaaatg tgaataagtc
    15001 catcttcatg aacaccaatg tctacaaaag caccaaagtc aacgacgttt ctcacagttc
    15061 cttcaagctt ctggccaatt tccaaatctt ttaaatcaag gatatcttga cgtaagattg
    15121 gtgcttcaaa gtcatcacga aggtcacgac ctggtttaag gagatcagca atgatatctt
    15181 taagggtttc ctgcccaata gccaatgttt ctgccatttg gggaacttga actgctgcta
    15241 aagttgcctt ggcagcgtcg tccaagtcct gaataccaag taccttaaag agttctttga
    15301 ctgctgggta ggactcgggg tgaactcctg tgttgtctaa aatatttttg gctcctggaa
    15361 ttctgagaaa acctgctgct tgctcaaacg ccttagctcc taaacgcggc acttttttga
    15421 tgtcagcgcg tgatgtcagt gctccatttt cttcgcggta tttgacaata ttttctgaaa
    15481 tcgttttgtt caaacctgac acatgtgcta ataaagatgg actagccgtg ttcacattaa
    15541 caccgacttg gttaaccaca gtatccacaa caaaaccaag attctcactc aactttttct
    15601 gactcacatc gtgctggtac tgaccgacgc caatagattt aggatcaatt ttaaccaatt
    15661 ctgctagtgg gtcttgcaag cgacgagcaa tagaaatagc agagcgcttc tccactgtga
    15721 ggtctggaaa ctcatgacgg gctaactctg acgctgaata aaccgaagca ccgctttcgt
    15781 taacgatgac ataggacgta tttgggaaat ctttcaaaac gtctgctaca aaggcttcac
    15841 tttcccgact ggctgttccg tttccaatgg caataatatc aatctggtaa gtctcaatga
    15901 gctgagtcag tgtttcttta gctgcttgaa tcttcgtttg gctagctggt gctacgggat
    15961 aaataacctg agtagtcaac aattttccag tctgatcaac gatagccaat tttgcacctg
    16021 ttcgaaaggc agggtcaaat ccaagaacca ttttcccttt taaaggagac actaacaaaa
    16081 gatgacggag attttcagaa aagaggtgga tagccccatc ttctgcggca tcactgagtt
    16141 ctgaacgaac ccgtctttcc atagctggaa caattttctt tttgatggtc tgattgatga
    16201 cctcttcaat ataagggttg gtttctttga accgcaccct gaaaaagcgt tgcattttct
    16261 ccaggttatg ctcaaaagac acttttaaga tgcctaactt ttcgccacgg ttaagggcta
    16321 aagtacgata tccttgcatg ttagacactt ggtcagaaaa atcgtaatag atttggaaaa
    16381 cctttttctc atccaactgc tcatctttaa gcgttgatac taaacggctg tactgccaaa
    16441 tctcattgta ggtccaagag cgtaatttag catcttctga catggcctcc acaaggatgt
    16501 ccacagctcc tgctagagct tcttgtgggc tggcaaatcc ttctgtgaca aagggttctg
    16561 ctgctgtttc aaggttttgc gcattttgta aaatcaaacg tgctaatggg aacaagcctg
    16621 cttcacgcgc aatcgtcgct tttgtacggc gtttttcctt ataaggcagg tacaactctt
    16681 ccaaatcagc gagtttttcg gttgcttcaa tactcgttcg taactgatct gtcagttttc
    16741 cctgttcctc aattttagcg agaatggttg ctttgcgctc attcagggta gtgagagact
    16801 tatccatatc aataatggac ttaatcacca cttcatctag atttcctgtt acttctttac
    16861 ggtaacgtgc aataaaggga atggtattgc cttgtgctgt tagggcaagc acctgttcaa
    16921 tttgatggag actaactgac aaagcctctg caatgttgtg attattgtta ttttccataa
    16981 tattgctatt ataacacaaa ccatgttaat gcaaaaaatg atagcgaaac attgtcctaa
    17041 tataaagttg cgtaaagaat caaaaaaagc tacttttagt aaataactga cgaaacccta
    17101 aataacaata cctaatttta aaaaagaaag aagtaaacag cacttccgct ttggcattgt
    17161 tctcaaatga tagtataata gacttatctt gaatgaaaga aggtcataga tatggcaatt
    17221 acccataaaa aaaatgatga acttgaaaaa atgctagcag gctttgcatc aatccctagt
    17281 tttgataagc ctttggaagt caatactgat ggtaaactag cgaccaaaga aaaaacgaca
    17341 gaacaaacaa aaccaagcaa accatagcta gtttgtctca ttctcttaac atatcgtcca
    17401 ttcgtttaaa ctgagttgag agatttttag cgatcaggct aacaaaacgt atcagtcgag
    17461 gctgaacatt cgtgtttcag cctcctcttt tatcatctag aaaggatatg gtgaatgtca
    17521 ctcttttcca accttcctcc cagtgtcttg caatggtttg cgatttttat gtccattatc
    17581 attgaagctc ttccttttgt gctcctagga actattttat ctggttgtat tgaagtcttt
    17641 gtaacgccag aattggttca aaaataccta cctaagcaaa aatgcttgcg cattctgttt
    17701 ggaacctttg ttggatttgt ttttccttct tgtgaatgcg ggattattcc catcatcaac
    17761 cgctttttgg aaaaaaaggt gcctagttat acggccgtcc cttttctggc aacagcgcct
    17821 attattaatc ctattgtttt gttcgctact tattctgctt ttgggaattc tttgcgcttt
    17881 ctgatacttc gcttggtcgg tgctgcacta gtagccatta cacttggggt aatgttagct
    17941 tttattgtag atgataacat tctcaaggat aatgctcaac ccgtgcattt tcatgattat
    18001 tctcatgaaa gcttgccaaa acgcatttat ctagcactgg tacatgctat tgatgaattc
    18061 ttcgacaccg gtaggtatct cgtatttgga accttgattg cctctgccat gcaaatatat
    18121 gtcccaactc gtgtgttgac aacgattgga cacaatccct tgacagccat tttgatcatg
    18181 atgctgatgg ctttcattct atcattatgt agtgaagccg atgcctttat cggagcttcc
    18241 ttattatcca cctttggagt ggctccagtt cttgcctttc ttttaattgg tcctatggtg
    18301 gatattaaaa accttatgat gatggtaaag acttttaaag gacgcttcat tgtccaattt
    18361 atcggcgtat ccgttcttat gattgccgtt tattgtttac ttgtgggggt gctctaatga
    18421 ttcgcttttt aattttagct ggctattttg aactaaccat gtatctccag ctgtctggca
    18481 aactggatca gtacatcaat gttcggtatt cttaccttgc ttatatttcc atggttttat
    18541 ctttcatttt agctcttgtt caactctata cctggatgaa aaacattaag gtacatagcc
    18601 atttaaccgg aaaaatcgca agactgacca gtccttttat cttggtcttt cctgttttga
    18661 ttggtctcct tgtgccgacc gtgaccttag attccaccac ggtttctgcc aagggttaca
    18721 cttttccttt ggctgcggga gcctctaaaa cgggagtcag tgatgacggg accaccattc
    18781 aatacctcaa acctgatacc agcctttact ttacaaagtc tgcctaccaa aaggagatgc
    18841 gtcaagaact ccataaatat aaaggcaaga aaccggtcac cattaccact gaaaattata
    18901 tggaagtgat ggaattgatc tatctctacc cagatgagtt tcttgatcgt gacatccaat
    18961 acactggctt tgtttataac gaaccgggcc atgacaacta ccaattcctt ttccgcttcg
    19021 gcattattca ctgtattgcc gactcaggag tgtacggact tttgaccaca ggtaatcaaa
    19081 ccagctaccc taacaacaca tggctaacag ttaaaggtcg ccttcatatg gaatatgata
    19141 aaaacttaga acaacatcta cctgtccttc aacttgctga ggttcatcaa accaaagagc
    19201 ctaataatcc ttatgtttac cgcgtttttt aaagactaat aaaaaagcac ttgtttttta
    19261 tcaaaacaaa tgctttttga gttttatcag ttagcatagg aacagagtca ccatcttaaa
    19321 caagacctat ttaggaaaaa ttatcctcaa ggtaacgtcc attggtttga atgacttgtc
    19381 ggtaccaatc aaacgatttt ttcttatagc gtgtgagttg accagtacca tcatcatttc
    19441 ggtcaacata aataaaaccg taacgcttac ttaattgggc tgttgacata gagacacaat
    19501 caatacagcc ccaagcagtg taacccatga cctcaacgcc atcttcaatc gctttggcaa
    19561 cttgtacgag atgctgactc atgtagtcaa tgcgataatc atcgtgaacc gtcatgctgc
    19621 catctgcggt ttgcaccagc tgatcctttg cacctaagcc attttcaaca ataaacaaag
    19681 gaatctggta gcggtcatag tactgattca agaccaatcg cagaccaatt gggtctatct
    19741 gccaacccca ctccgaagat tctaaatatg gattggacaa accacctaga atatttccct
    19801 gaccagatgt gtaagcttca ggattgtggg cttgtgtgac actcatgtaa tagctaaagg
    19861 atagaaaatc aaccgtatgt tccgctaata attccttgtc tccgtcttca aaaacaatct
    19921 caatcccatt ttctttaaaa tacgacttaa tatatgaagg atacttgcct ctcacatgaa
    19981 tatctgaaaa taagagatta agattttcaa atgcatgcgc agcaagtata tcacgaggat
    20041 cagaggtcat tgggtaagca ggcatcgcca aaatcataca cccaacttta acatcaggat
    20101 tgatttcatg cgctagcttt gtgacactag cagatgctac caattcatga tgaatagctt
    20161 ggtataaatc ttgcaggctc agcttttctt tttctgtcat gatgccacca ctggtaaagg
    20221 gcatgtgtaa aatcgagttg acttcgttga aggtcaacca gtatttgact ttgtccttat
    20281 agcgttccat gactgtctga gcaaagcgct caaaaaagcc aatcagacgt ctatctgtcc
    20341 aaccattata ggctttggcc aaatgcagag gtgtctcata atgcgacaag gtcactaagg
    20401 gttcgatacc atagttcaac aattcatcga ataagtcatc ataaaattgc aaacctgctt
    20461 cattgggctg gtcatcgtca ccatttggaa aaatacgaga ccaagcaata gacgttcgaa
    20521 agactttaaa gcccatctcg gcaaaaagag caatgtcttc tttgtagcgg tgataaaaat
    20581 caatcgcctc taaagttaaa ttatcgctgg taggactatc tgtccattct cctagtccac
    20641 catttggtag aacatcttgt acggacaaac cttttgcgtc tgcctcaaat gctccttcca
    20701 cttggttggc agctactgcg ccgccccata agaaatcttt tggaaaaatt cccattctcc
    20761 ctctcctttt aggttataaa atgactaaca aagcgtcctc tttagtcacc atttttttgt
    20821 catcttgaat aataatctcc aactgctcag ccgaattggt cacgaccaca ggactgatga
    20881 gtgaatagcc ttttgaagta atgaaatcaa tatccatttt tagaagtgcc tggcctcgtt
    20941 tcacgacatc gccaacagac actaactgct cgaaaccttg cccttttaac tcaaccgtat
    21001 caataccgac atgaatcaag acttccacac caggtgtgtt ttttaaggca acagcatgct
    21061 tggttggaaa gaaagtgatg acttcaccat caaagggggc atagaccaca ccttcgcttg
    21121 gtaatatggc aaatccttct cctaataact tggaagaaaa ggtttcatca ggaacttctg
    21181 atagaaaaag catctcacct gtcattggag catacaacgt ttgtttggtt gacaagccgc
    21241 tcttaacttg tgacatatct gctgcaacac tcacttgctc tggggattct tcatcaattc
    21301 ccatgaacca agtcaaactg aaggctaaca caatcgtcac agctccggca atcaaagcat
    21361 ttgtaaaatt agctccgcct gatgggttga tgtactgtgg taaaccaata atagaaggta
    21421 cgacaaaggt ataagaagca atattgacaa aaccaataaa ggctccgacc agaccacctg
    21481 aaatcatggc tgcatagagt ggctttttaa atttcagtgt gaccccataa agtgccggtt
    21541 ccgtgatacc tgccagcaaa gctgaaatcc ccgcggcaag ggcaacttga cgtgtttgtt
    21601 tctgctttgt tttaaaggca acagccaaag atgcggctcc ttgagccaaa ttagaagcca
    21661 acattgctgg taaaatcaag acatctggtg ttgcgaccga agcggccaaa aagattggtg
    21721 caaaagccca gtgcatcccc gtcatgacaa caagcggcat aatcgctccc aaaatggcaa
    21781 gtgctagcca cggagccaca tgataaatag cgagcatggt attggataac ccttgaccaa
    21841 taatcacacc aagaggacct acaaccacta aagccaaaaa gccagaaatc aaaatgatta
    21901 aggttggctg taagaagctt ttcatcacgc ttggcaccaa gcgattgacc catttttcaa
    21961 tgtattgcat caagtaaacc atcatcaaaa tgggaataac agatgagcca tagctagcag
    22021 gagtgactgg tgctccaaat aaagccaatg gtttaccttc tgctaccatt gcaacaaagg
    22081 ctggatgcaa taaaatccct gcgatcgtcg ctgctaaaac aggtgtcacc ttaaagcgcg
    22141 ccgctgctga ataggcaatc atgacaggca taaaataata agccgcatcg ccaaagaagt
    22201 taataaaggc aacggtttga gagtccgcac tcgctaagcc aagcatagga agcaagatcc
    22261 ccaccacttt gagcattcca ccaccaagaa gggctggaat cagcggtgta atcacgccag
    22321 caatggtttc aatcaagcgc tcaaggatac ttccttttgc ttttgaagaa tgatcttcat
    22381 cttgattgtc aaaatgccct aggcttaaaa aggcttggta ataattattg acatcattgc
    22441 ctaagataat ttggtactgg ccgtttttgc gcatcacgcc aatcacattt gaaatggctt
    22501 tgacttgctg atctttaact ttctcatcat ttttcagtac taagcgtaga cgtgttacac
    22561 agtgtgtcac acgttgaata tttgttttgc caccaaccgc cgctaaaata gccttggcag
    22621 tttcttgata cgtcatatta agtctccttt aaatgtttca ctaaacgttt aacatgaacc
    22681 gtcaaataca aaagttcgct tgaattaagg tggtagttgt accgcttttt tatctcctca
    22741 ctaatatcta agacgcaccg atattcttta gggtatttcg ttttcaccac taaaagcagt
    22801 tccgcatcat catcatcgta agacatctct gataacacgc gttgagcaaa taatttaata
    22861 tgggtcataa agcggtaata atcgatggat gtgtcatcca attctgtttt gaagtctgtt
    22921 ttgatttttt gctcaatata agaaacaatc tccgtcaggc gatgtggctc cttaaaagga
    22981 gtgtccaaac tagcattgac aaaatgcatg gcaataaaag ctgcttcatc aatagctaga
    23041 gtgactccta gattacgctc aattagctct aaggctttta cccctagact atattcatca
    23101 ggataatagc gttgaatttc ccaccgtagt gggttatgaa tcaacattcc ttgctcatgc
    23161 ctttcaatag cagagtgaat atgatccgtt aaattaatat agagaatttc atctaaggct
    23221 ttgcctaatt taattttacc tagattgata attctctctg agcaagcaac aacttcttgt
    23281 ggcaccttaa taaataactc tgtgaagcga ttcatattgt cactattttt taaaataaat
    23341 gatgtttcga tagcattaag ctcaatacta tctccaactt tttttccaaa ggcaatccct
    23401 tttcccatca ataaaatatc taatccttga tggttggtcg aaatcgccgc attatggttt
    23461 aaaacgcgtt taatcaacat aaaagtccta gtcctttagt atcacaataa aaaatgacct
    23521 atccaaaagc tcgctaaaaa gcacttttcg aataggtccc tgctcacaaa actgtgataa
    23581 catcctttaa tattctgatt gttatgtctc tagcctgctt acctgaagta atcacatctg
    23641 agaacgcttt aatgttatca tctctttaag attctgtcaa gcgttttcaa aaaattctct
    23701 gaaagagcaa ctattgttat tcgtatctat tgatttagca aaaaagagtt tctgacaatt
    23761 ttaagattat atgatacaat aacaatcgat tagataaagg agttatcatg tcacatcatc
    23821 aacaaaccgt ttcaaaacaa acaattatgg cgattatcgc catagcactc attggttttt
    23881 caggaatttt gtctgaaacc agtatgaatg tcaccttccc gacactgatg tcagtctatc
    23941 agttgccctt aaatagcttg caatggatga cgaccattta tttactagca gtggcgatta
    24001 tgatgaccac ttcggctaca ctgaaaaaaa atgtgcggga aagacccctc ttttttatgg
    24061 ccacaggtct ttttacattt ggcaccatct tggccgttct gacccattcc tttgcgatca
    24121 tgttgctagc ccgcattttt caaggcattg gtactggtct ggtaatgcct cagatgttta
    24181 atataatttt agagcgtgtc ccaatgcata aggtaggtct atttatggga tttgctggtc
    24241 ttattattag cttagcacct gcttttgggc ctacttatgg gggctttatg attagccatt
    24301 ttagttggca atggattttt atctgtatac tccctgtacc actgattgca ggtattctag
    24361 cttattatta cctcgaagat tctccagtaa gcgaaaaagt accctttgac tggttggcat
    24421 ttattgcact atcgattagc ttaacttctg ccttattagc tattactagt ctagaaaacg
    24481 gaagtgttaa tttgtattac ttagggcttt ttattctcag ctttgtcctc tttctctaca
    24541 agaatctcac agctaagcaa ccctttcttg atattcgcat tctcaaaatt ccctctctaa
    24601 cctttggcct gattcccttt tttgtcttcc agctgattaa tttaggcata aattttctaa
    24661 cgccaaactt tattgtcatg gaaaagattg ctaatagttc tcaagctggt atggtgttac
    24721 tacctggtac cttactcgga gctctactag cacctgcttt tggtaaactt tatgatcaaa
    24781 aaggagcaag actttcgctt tatttaggaa atgccttatt tagtttatca ttgattatta
    24841 tgacacttca aacaagacat tttatgcttt taccattcac tcttttatat attttattca
    24901 cgtttgggcg taacatgggc tttaataata gcttagccac ggctattcga gaattgcctg
    24961 ccgagaaaaa tgccgatgcc acggccattt ttcagatgat gcagcaattt gctggcgctc
    25021 taggaactgc tatggcatca ctgatagcaa atagtcaacc agaattcaca agtggtgtcc
    25081 aatctgtcta tcttctattt accttctttg ccttatgtaa ttttgctttt ttcattgcca
    25141 tgtttaaaca tttagctaaa aaaggacttg cctaagctaa cttacttaaa aaccagcctc
    25201 gttctgttga acaagactgg tttttttctt ataaaatacc ttctaaaaga cctttcataa
    25261 agtcttctga gtggaattct ccaatatcat ccactttttc accaaatccg atgaacttga
    25321 ctggaatgtc taattcttga cggatggcta ggaccacccc accttttgca gtgccatcaa
    25381 ttttcgttaa aatcaaacct gttaatggtg ttatttttga aaattccttg gcttggctaa
    25441 gcgcattttg acctgttgac gcatctaagg ccaaaagcgt ttcatgaggg gcatctggta
    25501 gcacgcgctt aatgatacga cccatttttt ccagctctgc catgagattt tctttgtttt
    25561 gcaggcgacc agccgtgtca atcaggagaa tatctacacc ttttgccaca gctttttcca
    25621 tcccgtcaaa aacaacagac gctggatcag ccttttcagg gccagtaatg actggcacat
    25681 ctactcggcg tccccattcg actagctgag ccacagcccc tgctcggaag gtatctgctg
    25741 ccaccaacat gactttttta ccttcttgtt tgtaacggta agccagcttc ccgattgaag
    25801 tcgttttacc aaccccattg acacctacaa aaagcataac cgtcaagcca tcttgataat
    25861 taatggcttc attataacgc ccgtcttttt catagatatc taccaatttt tccacaatca
    25921 cacgtttcaa ggcatctggt tttttcgcat tttccagttt ggcttcataa cgcaactcct
    25981 ctgtcaaagt tgtcgccaca tgtacaccga catctgataa gatcagcatt tcttccaagt
    26041 cttcaaagaa ttcttcatcc actcgcctga aattggcaaa gaaactgttc agacgagctg
    26101 agaagccagt ccgcgttttt tttaagctac gcttgtattt ttcttgatct gtctcaggaa
    26161 tggtatcgtg ggttgccttg ttttgagaag cttctgctga ggtagaggcc tgattttctt
    26221 gtggaacttc ttctggcatc actggaaccg ttgccgctgc tttttcttga aggctttttt
    26281 caagagcagc cttacgacga tagtagtctt ccataacctg ttggctactg gattgctctt
    26341 ttaaagtgtc tactgcttct tccttcgccg aatcatttga ggcatcagct tgagcttgtt
    26401 ttgttggaaa ctgttccaca actggctggt caacaaggtc ttttggttct gatgccgtag
    26461 attgactaag ttcacttacc ttaaggtctg ttttgtcggc agcaaactca ttggtatctt
    26521 ctgatgaatg attactatta tcacctgttt cttcctcaac ctgtgcattt actgaagctg
    26581 cttcgggacc attttccacc gaacctgcgc cctctgaaga aacgtcctct tgttgaacca
    26641 cctcaatctt gtcttgctca ttggcttttt cagaaagctc ctctttctga gttgtttctg
    26701 tcaaaagatt ttcttctaac ttttcctcag ctaccttcgg ggtttctttt ttcccaaata
    26761 aacgatcaaa taatcccatt aactctcctc ttctaaaata aatgtcttca cagcttctgc
    26821 aactccagac tcatcattgg tcaaggtggt cacggcatcg gcaacggctt tagctcctga
    26881 aacaccatta gccatagcta ctccaagtcc tgcccattct aacatcgcaa agtcgttagc
    26941 ttcgtctccc atagccatga catgtctagc gtcaaggcca aggtgctgac aaagcaagtt
    27001 taatccaaaa gctttatcaa tgccttttgg catgatttca aaaataatat ctcgtgattt
    27061 aaaggcttca aaatcctcaa ataagcttgg ggatagcttt ataatctgct gatccaaaaa
    27121 gtctggatcg gtgactgtca caattttgtt ataggtaatg tattttggta gttccgctac
    27181 agatgtcacc tcaataaagg tcaacagtgg gttagctaga tggtactgcg aatgcctacc
    27241 gtccttactt ggaatgctat acacatcccc accactgata atatctgttg gtaagccaac
    27301 cgcctctaaa gcttgctgaa tctggcagac ctggtcaaaa ctgagagaac tcttatccaa
    27361 aacctcccct gtatttcgct gaaccaaacc cccattaaag gtaatactgt agtcatcgtg
    27421 gtcaagcaag tccaactctt ctagcaagtt accgatggcc tttagagggc gacctgtggt
    27481 aataaccacc ttaacccctt tttctctagc cgctgctaag gcttttttat tggcatctgt
    27541 gacaattttt tcagcgttgt agagggtacc gtctaaatca agcgccaaaa ttctaatatt
    27601 catgagttac actagtcctt ttaaatacgt tagtactgct ccgtcattac agtggccaat
    27661 gacttggtct gaaatcactt tgatttcagg tcttgcattt tccgtagcaa tagccctacc
    27721 agcaaactcc aacatctggt aatcattaaa attatcccca aaagcaatcg tttctgcttt
    27781 cttaatgccc aaggcttgac aaagatgctc cataccaaag cccttattca cctcttttaa
    27841 gataatatca atggaatcaa agccggtggt cactgcagtg gcataaggga gggcttgatt
    27901 caaccaatcg cttccttcta agacggtatg gcctgtgaag ttggtagaaa ctttaaaaat
    27961 ggcgtcattc tccatatctt caaaaccatt aataacctta acattagcat agtaatgttt
    28021 tgttttttga atgtactctt ctgatgcgcc ttttaaaata taggctgcct tttgcccaga
    28081 aaaaaccata cctgtttcta catagtgagg attggctaaa accttttttg caacttcggt
    28141 atactgctct ttggtcatcg tatctgcaaa tagaacctca ccatggtatt gaaccacgga
    28201 accattttct gcaataacag caatctgatc caaaaagggc tcaaagagct gatcaatggc
    28261 taagagcgag cggccactcg aaaccgcaaa taaaatgcct ttttcggcta actttggcaa
    28321 gagcgcagct agttgctctt gattataagt accatcttca gctaggaagg taccatccat
    28381 atctgttgct attagtttta tcatacaatg tctccttttt ttactctagg ggggtgcaaa
    28441 cgccatttag ggtgtgcact ttttaacgat ttaaataagc cccatcattt ctgcattctg
    28501 ttcaattttt cttattatat cataaaaagc agctttcatt ccattcgtaa aaaacagcca
    28561 gattatattt cgataacctg accgtttttg aagtgaactg ctactttttt atttttataa
    28621 atgaccactg gatgtatact ataaaagtag acaaaacttt gtgtgttaca atctgtttta
    28681 aaagacacaa aaacgaaagg acaacctatg tcaacagtta aacgctacag atgaagaatt
    28741 caaacaatcc cttgtcaact tttatcaaac tggaaaaact cagtctgatc tctgtaaaga
    28801 ctatggggta tccgcttctg cgcttgcaaa atggatcaaa cagtattccc aagtcaaact
    28861 cgaagataat tctgtactta ctgccaagca aatacaagag ctacaaaaac gtaatgcaca
    28921 gcttgaagag gagaacctta tcctaaaaaa agcaagtgcc atattcatgc aaaacttaaa
    28981 gtaagactcc tcgctgttta tcggttacgc tttgaacacg ccacaacaac cttgtatcgt
    29041 gttttacgtg tcaatcgctc cacttactat aaatttctaa aacataagcc ctcaaaaaga
    29101 gaattggata agcaagttta tagaaaacaa atacttgaga tttataccaa agcaaacaaa
    29161 agacttggtg tgaagtctat caaagtcatt cttcaaagag actacgacac aaaaatctct
    29221 gaaggaagaa tttaccgtct gatgaagaat atggcgctcc ctaacatggc aaccgttaag
    29281 ccaaaacgag ctcttaaaag gactcaaaaa acgtatcctc aaaacttact caaccagaaa
    29341 tttaatcctg acaaacctaa tcaagtctgg acaacagact tcacctacat ttctattgga
    29401 tataagaaat atgtctatct ctgcgtaata cttgatctct attctagaaa atgtattgct
    29461 tggaaactga gtcatcgtat ggatgcaaag ttagcatgtg acactctaga attagctctt
    29521 aataaaagaa agattgaagg aacacttctc tttcattccg accaagggtc acaatttaag
    29581 gccagggaat tgagaaaaat aattgatgac aacactatca tgcattcttt ttctaaacct
    29641 ggatatcctt atgataatgc cgtaacggaa gcttttttca agtatttaaa gcatagacaa
    29701 atcaaccgaa aaaagtatca aaatatcaaa caggttcaat tagactgctt tgaatacatt
    29761 gagaattttt ataacaatta caacccacat acggctaatc taggactaac ccctaatcag
    29821 aaagaagaaa attagtttaa cgtaataaaa taacacggtt ttctgtctac ttatttgaca
    29881 ttagtccaaa atacatccta atggtgtcgc tttttttatt tcactagaca ttcgttctag
    29941 tttaggatat aagaaggtct caaatttttt tcaggatgtt tattccaaac atccaatcac
    30001 ctttctatat aactgttcat ttagtggtat agacaaacag aaatactccg tttctagttt
    30061 catagaagac ggagtatttt ttagtagaga cgtctggatt gatagatagt tggtatatag
    30121 ctcatcccta ctaggctttc attatagact atggtgggtt tcgttgacaa caatatttga
    30181 ttattattct aaatgacagt atacatcaac tatcaagtat gcttttaatt ttatttttta
    30241 aagctacaga tgaaaatctg tattccatac ttccatctaa tcgaacaata atataatgat
    30301 gtctcgaata taattcatgt ttaaaaaact ttttgatttt tttataagga aactcaaaaa
    30361 cggaacaatg atacccactt aatttatttg ct
//
LOCUS       DATTYN010000022        26850 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.22, whole genome shotgun sequence.
ACCESSION   DATTYN010000022 DATTYN010000000
VERSION     DATTYN010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26850
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.22"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            477..695
                     /locus_tag="VB649_001229"
     CDS             477..695
                     /locus_tag="VB649_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670181.1"
                     /translation="MYPRIRNLREDNDFTQKFVANLLSFSHANYAKIERGEVALMADV
                     LVQFSKLYNVSIDYLLGQTDYPYRFHNK"
     gene            complement(766..909)
                     /locus_tag="VB649_001230"
     CDS             complement(766..909)
                     /locus_tag="VB649_001230"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670182.1"
                     /translation="MGISPTGLLRWQPERSEVSLSLFVVMADREPLYFIANNYRSYHG
                     VSH"
     gene            996..1216
                     /locus_tag="VB649_001231"
                     /pseudo
     CDS             996..1216
                     /locus_tag="VB649_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903600.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            1372..1593
                     /locus_tag="VB649_001232"
     CDS             1372..1593
                     /locus_tag="VB649_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEP1670183.1"
                     /translation="MKEAYDELVRIRYEFSNNLSIENDNISFENYMNTIYLRAYKQKV
                     QAVTYEIALPHHKLFIQYFGSKLLKGITA"
     gene            1918..2301
                     /locus_tag="VB649_001233"
     CDS             1918..2301
                     /locus_tag="VB649_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEP1670184.1"
                     /translation="MKVHTTLEKDENGNWYRKDQTKTPAGERLIELDDVTIVLLENWR
                     RNQVVNTDTDFIISRFGEPFCKSTICRVIKHKAQEVGVPVITGKGLRHSHASYLINVL
                     KKDILYVAKCMGHADKSTTLNTYSH"
     gene            2564..3799
                     /locus_tag="VB649_001234"
     CDS             2564..3799
                     /locus_tag="VB649_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEP1670185.1"
                     /translation="MIKRWVVLFFMVLTCSGFGKTVLAADFQVGAEHAIVVEADSGRV
                     LYEKDAKTPDAIASLTKLVTAYLVLDKVKSGQLQLSDQVNLSDYAFELTKDRSLSNVP
                     FDKKTYSVQDLLTATLVASSNSAAIALAEKVAGSEPHFVNQMREQLSHWGITSGKILN
                     ASGLPNEVLKDHRYPGSALEEENTLSAQDVAVVTMHLLEDFPEILEITKQTEVNFAGN
                     SIKSFNQLLPGMAKGRAGVDGLKTGTTDLAGHCLVVTSIENGMRVITVILNADGSDKN
                     QNTRFEQANRLLDYVARTYCRRKILKKGSLVLERSLPIQDGQVKELPVSVAEDVTIIL
                     QQGEQVPKPKQFMISETPLLAPITKGEVVAYLTSPRITDQSVRYLKEPKRIPLKASQS
                     LKKASDLQLWWRDFLEKRR"
     gene            complement(3916..4878)
                     /locus_tag="VB649_001235"
     CDS             complement(3916..4878)
                     /locus_tag="VB649_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEP1670186.1"
                     /translation="MNNRHKRRQKRKAFTLINLILLFACILGLTLIFYLYQGSNKFGL
                     SDVSQFVPKISLFHHKKTAKKETTKLKKTHFDSSKSQKKAHSKLTWTKQETPVKIPIL
                     MYHAIHVMSPEETANANLIVNPDLFDQQLQKMKDEGYYFLSPEEVYRALSNNELPAKK
                     VVWLTFDDSMIDFYNVAYPILKKYDAKATNNVITGLTEMGSAANLTLKQMKEMKQFGM
                     SFQDHTVNHPDLEQASPDVQTTEMKDSKDYLDKQLNQNTIAIAYPSGRYNDTTLQIAA
                     RLNYKLGVTTNEGIASAANGLLSLNRIRILPNMSPENLLQTMEP"
     gene            5208..6485
                     /locus_tag="VB649_001236"
     CDS             5208..6485
                     /locus_tag="VB649_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEP1670187.1"
                     /translation="MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHI
                     VGTNGKGSTVNHLQHIFTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRI
                     RPLTERLVQETDFGEVTEFEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAM
                     VVVCPSIGLDHQAILGETYADIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGA
                     SIWEWQEQFQMAENASGYRFTSPLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYS
                     RLTSDHIREGLANSLWLGRTELLAPNLMIDGAHNNESVAALVAVLKNNYNDKKLHILF
                     GAIDTKPIADMLVALEQIGDLQVTSFHYPNAYPLEKYPERFGRVADFKDFLALRKHAK
                     ADDFFVITGSLYFISEIRRYWKKHIEKSVLLTH"
     gene            6520..7104
                     /gene="folE"
                     /locus_tag="VB649_001237"
     CDS             6520..7104
                     /gene="folE"
                     /locus_tag="VB649_001237"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEP1670188.1"
                     /translation="MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKM
                     YAEMFLGLGKDPKEEFTAVFKEQHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSD
                     GRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRG
                     IKKPGSKTITTTARGLYKESRAERQEVISLMTKD"
     gene            7113..7913
                     /gene="folP"
                     /locus_tag="VB649_001238"
     CDS             7113..7913
                     /gene="folP"
                     /locus_tag="VB649_001238"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEP1670189.1"
                     /translation="MKIGKFVIEGNAAIMGILNVTPDSFSDGGAYTTVQKALDHVEQM
                     IADGAKIIDVGGESTRPGCRFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARA
                     ALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRA
                     QAALDAGVPKNNIWIDPGFGFAKSVQQNTELLKGLDRVCQLGYPVLFGISRKRVVDAL
                     LGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM"
     gene            7920..8279
                     /gene="folB"
                     /locus_tag="VB649_001239"
     CDS             7920..8279
                     /gene="folB"
                     /locus_tag="VB649_001239"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEP1670190.1"
                     /translation="MDKIVLEGCRFYGYHGAFKEEQTLGQIFLVDLELSVDLQAASLS
                     DQLTDTVHYGMVFDSVRQLVEGEKFILIERLAGAICEQLFNEFPPIEAIKVAIKKENP
                     PIAGHYKAVGIELERQR"
     gene            8276..8776
                     /gene="folK"
                     /locus_tag="VB649_001240"
     CDS             8276..8776
                     /gene="folK"
                     /locus_tag="VB649_001240"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEP1670191.1"
                     /translation="MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETT
                     AWGKTGQADFLNMACQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFG
                     EEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKFLRDYLAALDQSDITLFS
                     AQQTEF"
     gene            8926..9813
                     /gene="murB"
                     /locus_tag="VB649_001241"
     CDS             8926..9813
                     /gene="murB"
                     /locus_tag="VB649_001241"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEP1670192.1"
                     /translation="MITELHGIDIRENEPLKHYTYTKVGGPADFLAFPRNHYELSRIV
                     AYAKKENMPWLVLGNASNLIVRDGGIRGFVIMFDKLNAVHLNGYTLEAEAGANLIETT
                     KIAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEISHIFLSAKVLTPSGEIKTISAR
                     DMAFGYRHSAIQETGDIVISAKFALKPGNYDTISQEMNRLNHLRQLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMEANLKGHRIGGVEVSEKHAGFMINVADGTAKDYEDLIAYVIETV
                     ENHSGAKLEPEVRIIGENL"
     gene            9859..11013
                     /locus_tag="VB649_001242"
     CDS             9859..11013
                     /locus_tag="VB649_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670193.1"
                     /translation="MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGS
                     GKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKKEIAKRVRETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIG
                     LDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL"
     gene            10997..11791
                     /locus_tag="VB649_001243"
     CDS             10997..11791
                     /locus_tag="VB649_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670194.1"
                     /translation="MKKTSSLFSIPYFLWILFFVVAPVTLLFYKSFFDIEGRVTLANY
                     ETFFSSWTYLRMSVNSILYAGIITLVTLLISYPTALFLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGIGPQQILFTDFSFIFVASYIELPFMMLPIFNA
                     LDDIDHNVINASRDLGASEFQAFSKVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTQNWGMGSTIGVVLILTMVAIMWLTKEKSK"
     gene            11788..12564
                     /locus_tag="VB649_001244"
     CDS             11788..12564
                     /locus_tag="VB649_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670195.1"
                     /translation="MKKFANLYLASVFVLLYIPIFYLIFYSFNKGGDMNGFTGFTLEH
                     YQTMFEDSRLMTILLQTFVLAFSSALLATIIGTFGAIFIHHVRGKYQNAMLSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGMSSVLLSHIAFSIPIVVLMVLPRLKEMNQDMVNAA
                     YDLGANYFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARQGISLDINALSTIVFFFSILLVIGYYYMSQDKEEKHA"
     gene            12557..13630
                     /locus_tag="VB649_001245"
     CDS             12557..13630
                     /locus_tag="VB649_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP1670196.1"
                     /translation="MRKLYSFLAGVLGVIVILTSLSFILQKKSGSGSQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEN
                     LLNKLDKSKLVGMDNIGKEFLGKSFDPQNDYSLPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYKNSIMLIDGAREMLGVGLTTFGYSVNSKNLEQLQAAERKLQQLTPNVKAIVA
                     DEMKGYMIQGDAAIGITFSGEASEMLDSNEHLHYIVPSEGSNLWFDNLVLPKTMKHEK
                     EAYAFLNFINRPENAAQNAAYIGYATPNKKAKALLPDEIKNDPAFYPTDDIIKKLEVY
                     DNLGSRWLGIYNDLYLQFKMYRK"
     gene            complement(13685..14350)
                     /locus_tag="VB649_001246"
     CDS             complement(13685..14350)
                     /locus_tag="VB649_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEP1670197.1"
                     /translation="MNVLIIEDDPMVDFIHRNYLEKLNLFDRIISSDSMKAVQSILTD
                     YAIDLILLDIHITDGNGIQFLEKWRAQHIPCEVIIISAANDGNIIRDGFHLGIIDYLI
                     KPFTFERFQESIQQFVTHREHLANQQLEQAQIDQLKCLTSKKDTKNKQLLEKGLSEST
                     FQWIMENIKAFDQPFTIQELASACHLSHVSVRKYIAYLEENKQLNSQQIFTKVGRPYR
                     VYW"
     gene            complement(14331..15872)
                     /locus_tag="VB649_001247"
     CDS             complement(14331..15872)
                     /locus_tag="VB649_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1670198.1"
                     /translation="MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETH
                     LLTSTGKMLASHQAIKELLLNNQPNAKTTAYTNSIASIYNLDYVVVMNMKGIRLTHPN
                     PKNIGKPFQGGDEEAVLAGKKVISTAKGTLGKSLRYLVPVFDGDKQIGAIAVGIKLTT
                     LNDVALTSKRNYTLSLLLCLLISLLVTSVISFRLKRQLHQLEPSEIYQLFEERNAMLD
                     QIEAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNHLFPDFPKLSLQEGHEQ
                     LFRYGEEDYLLAISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHK
                     FMNQLHVIYGLVDIAYYDQLKIYLDSILEPENEILTSLSVLVKEPLLASFLIGEQEKY
                     QELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLRPKSLVLSIQHDQNHL
                     ISHYTLTDNWIDLERVQPIFDLPYFQQLLTDTNSQFHQHQTVTELQFSVTTPYVGGQH
                     ERFNH"
     gene            16033..17364
                     /locus_tag="VB649_001248"
     CDS             16033..17364
                     /locus_tag="VB649_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HEP1670199.1"
                     /translation="METISKKMPQKDLSEHSKAWQNRRIGSVPLPVYLVLATLILVTG
                     WLQQLPVNMLGGFAVILTLGWLLGTIGATIPGLKHFGGPAILSLLVPSILVFFNLLNP
                     NVLEATNVLMKQANFLYFYIACLVCGSILGMNRKILIQGLFRMIIPMLLGMVCAMGVG
                     TLVGVILGLDWQHTLFYVVTPVLAGGIGEGILPLSLGYSAITGVGSEQLVAQLIPATI
                     IGNFFAILCTALLNRFGEKHPSYSGQGQLVKIGHSEDMSDALKDNSGALDVKLMGAGV
                     LTACSLFIAGGLLQHLTGFPGPVLMIILAAFLKYLNVIPQETQNGAKQLYKFISSNFT
                     FPLMAGLGLLYIPLKEVVATLSWQYFIVVISVVLTVVSVGFFVSRFLNMNPVEAAIIS
                     ACQSGMGGTGDVAILSTADRMNLMPFAQVATRLGGAITVITMTAILRIIFS"
     gene            17396..18562
                     /locus_tag="VB649_001249"
     CDS             17396..18562
                     /locus_tag="VB649_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HEP1670200.1"
                     /translation="MENQLGQLALEQAKTFGGKLEVQPKVDIKTKHDLSIAYTPGVAS
                     VSSAIAKDKTLAYDLTTKKNTVAVISDGTAVLGLGDIGPEAAMPVMEGKAALFKAFAG
                     VDAIPIVLDTKDTEEIISIVKALAPTFGGINLEDISAPRCFEIEQRLIKECHIPVFHD
                     DQHGTAIVVLAAIFNSLKLLQKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDK
                     FGIINEQEAAQLAPHHLDIAKVTNREFKSGTLEDALEGADIFIGVSAPGVLKAEWISK
                     MAARPVIFAMANPIPEIYPDEALEAGAYIVGTGRSDFPNQINNVLAFPGIFRGALDAR
                     AKTITVEMQIAAAKGIASLVPDDALSTTNIIPDAFKEGVAEIVAKSVRSVVLKS"
     gene            complement(18644..19693)
                     /locus_tag="VB649_001250"
     CDS             complement(18644..19693)
                     /locus_tag="VB649_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEP1670201.1"
                     /translation="MKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTTICGTDLHI
                     LGGDVPACKEGTILGHEGIGIVKEVGDAVTNFKIGDKVIISCVTSCHTCYYCKRGLSS
                     HCEDGGWILGHLINGTQAEYVHIPHVDGSLYHAPDTIDDEALVMLSDILPTSYEIGVL
                     PSHVKPGDNVCIVGAGPVGLAALLTVQFFSPANIIMVDLSQNRLEAAKTFGATHTICS
                     GSSEEVKAIIDDITNGRGVDISMECVGYPATFDICQKIISVGGHIANVGVHGKPVDFN
                     LDELWIKNITLNTGLVNANTTEMLLNVLKTGKIDATRLITHHFKLSEVEKAYETFKHA
                     GANNALKVIIDNDIS"
     gene            19929..20660
                     /gene="aphA"
                     /locus_tag="VB649_001251"
     CDS             19929..20660
                     /gene="aphA"
                     /locus_tag="VB649_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HEP1670202.1"
                     /translation="MKKEFTSILFTVSFCGIIALPVEASGPKVPYTQEGITAISNQAT
                     VKLISIADIASSLEGQKPITVSFDIDDTLLFTSQYFQYGKEYITPGSFDFLHKQKFWD
                     LVAKRGDQDSIPKEYAKQLIAMHQKRGDKIVFITGRTRGSMYKKGEIDKTAKSLAKDF
                     KLDKPIAINYTGDKAVKPYQYDKTYYIKKNGSQIHYGDSDEDINAAKEAGARPIRILR
                     APNSTNLPLPKAGGYGEEVLENSAY"
     gene            20838..22370
                     /locus_tag="VB649_001252"
     CDS             20838..22370
                     /locus_tag="VB649_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEP1670203.1"
                     /translation="MENHKNEFTFSNKSIIAYVWRGVVVGIIAGVIVSLFRLLIEVTA
                     DWVIEWYRYAHINSLLLLPILSVSLLAVLFVGFLVKSDSDIKGSGIPHVEGELKGLMS
                     PDWWSVLWKKFLGGIMAISMGFMLGREGPSIQLGAMSAKGLAKFLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLIWITALVASLVANFISLNIFGLKPVLA
                     MSEAMPFLGLNQYWLLLLLGLFLGCLGYLYEIVILNFNKLYVILGSWLHLPAYFYGII
                     MVFLILPIGYYLPQLLGGGHGLILSLSNQQLPLMTIFFYFIIRFIVSMFSYGSGLPGG
                     IFLPILTLGALAGLLFGQIASQLGLLNQSFLSLFLILGMAGYFAAISKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVSYLVMDLLNGQPIYEAMLDKMAMKHPTNLVEPTLIELTVG
                     DKIAGKYVKELKLPENVLITTQIHHQKSQVVSGNTRLLSGATIFLVVNEADTGFVREV
                     LM"
     gene            22533..23147
                     /locus_tag="VB649_001253"
     CDS             22533..23147
                     /locus_tag="VB649_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEP1670204.1"
                     /translation="MLEIVSEELRHYQEQKLIEYRNKNQLAPKGGIVFAGDSLIEFFP
                     LKKAFGSCLPIINRGIAGIDSQWLLRHFSVQITDLEPKHIFLLIGCNDIGLGYDKCHI
                     VKTIVELISQIRSHCVYSQIYLLSLLPVSNNPRYQKTVKIRTNAMIDAINKDLAMIPT
                     IEFINLNTCLKDEKGGLSDENTLDGLHLNFPAYAKLAEIIQAYI"
     gene            23306..24454
                     /locus_tag="VB649_001254"
     CDS             23306..24454
                     /locus_tag="VB649_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEP1670205.1"
                     /translation="MIIKGVTMKFEKKQVFYLVLTFILCYGILANWRNGTAIVTTIYK
                     TSLPFFYGAAGAYIVNIVMSAYEKVYVYIFKDWSHVLKVKRGICLLLAYLTFFILITW
                     IISIVIPDLITSISTLTKFDTITIQEVVNNLEHNKLLARTIQYIGGDGKLTETIANYS
                     QQLLKQFLTVLTNILTSVTVIASAIINLFISFVFSLYVLASKEDLCRQGNTLVDTYTG
                     KYAKRIHYLLELLHQRFHGFFVSQTLEAMILGSLTASGMFILRLPFAGTIGVLVAFTA
                     LIPVIGASIGAAIGFILIMTQSMSQAIIFIIFLIILQQIEGNFIYPKVVGGSIGLPAM
                     WVLMAITIGASLKGIVGMIIAVPLAATLYQVIKDNIQKRQAIQKKQVS"
     gene            24503..25183
                     /gene="radC"
                     /locus_tag="VB649_001255"
     CDS             24503..25183
                     /gene="radC"
                     /locus_tag="VB649_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEP1670206.1"
                     /translation="MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHV
                     LELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTD
                     SVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILY
                     YACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYS
                     FREKSTLF"
     gene            complement(25185..25879)
                     /locus_tag="VB649_001256"
                     /pseudo
     CDS             complement(25185..25879)
                     /locus_tag="VB649_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
     gene            complement(25889..26533)
                     /locus_tag="VB649_001257"
     CDS             complement(25889..26533)
                     /locus_tag="VB649_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEP1670207.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHY
                     RFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERITNTDIETAILTVPSIH
                     AQEVTDQLIEAGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(26784..>26850)
                     /locus_tag="VB649_001258"
     CDS             complement(26784..>26850)
                     /locus_tag="VB649_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEP1670208.1"
                     /translation="DKFYFLMDSLVEREIFSKTVV"
BASE COUNT         8209 a         4481 c         5543 g         8617 t
ORIGIN      
        1 ctatctgatc aatcatatta ttagctatat atttagtaca ggtgtggcat taggtatttc
       61 aatggtaggt gttattgctg cagctttttg tgaaacgagc cttggtgata aggtatggtt
      121 tcttattcca tgggcatggc ttttaagaat atcagatact ctatataacc aacagaaaat
      181 ggcaattgtt ccacttattg ttatattttt tgtttcatgc acagtagctt tacttcatat
      241 acgaatattt aaaagttgga atcaagactg tttgacaagt agttaaatac atctattttg
      301 tttacctaac aatcaatatg atttttaagt tataaatact atctaacttg tttaactaaa
      361 aaatgactat aaaatttcaa tggtttacta gcttatattt aatagacttg tccaaatagg
      421 acaattaaac attttttaat caaatctcct ttatactgat attaggagaa tgttagatgt
      481 atccgcgtat taggaatttg agagaagata acgatttcac tcaaaagttt gttgcaaatt
      541 tactttcctt ctctcatgca aattatgcaa aaattgagag aggagaggtt gccttaatgg
      601 cagatgttct tgtgcagttt tctaaactct ataacgtcag tattgattat ttattagggc
      661 aaacagatta tccgtatcgt tttcataata aataaaagtc tcgccttgat ttgttcattg
      721 acaactgaat aaaccgaggt gggactttct tgtttgtcga gcaatttagt gagatacgcc
      781 gtgataggag cgataattat tagctataaa atagagtggt tctctatctg ccatgaccac
      841 aaatagggac aatgatactt ctgaacgttc aggctgccag cgtaaaaggc cagtgggtga
      901 gattcccatg agtgatttaa ccagtcatac ccacggaggt tgtaattttt ttgaaaggag
      961 tggaggtgtg aaaatagtaa catataaaaa gcttgatgaa tattggtttt ctcgaacata
     1021 ctgcaagaaa tattattaga gaagcaaaaa gaatagctat aaaaaagttg aagaagctcg
     1081 cgaacttgaa caaaatgcgg tacaattaag taaatcgccc tttgacaata gaagacttgg
     1141 tattgctcct aaagatattg tagaagagtt agtaggtgtt ctactctctg aagaaagttt
     1201 agaaagtgag aattaaagat gactataaaa aatcaaaaaa agtacaaagg tgtttattgt
     1261 gataagaatg ggaagatatt ttatcaagct gatcttggtg tagatccagt aacaggtaaa
     1321 cgagttcaaa agaaagccag aaagaattag tatggaaagc catttggtac aatgaaagaa
     1381 gcgtatgatg aactggttcg gattaggtat gagttcagta ataatcttag tattgaaaat
     1441 gacaatatat cgtttgaaaa ctatatgaat actatttacc taagagcata taagcaaaag
     1501 gttcaggctg taacttatga aatagcctta ccacatcata agttatttat tcagtatttt
     1561 ggttctaaac ttttaaaggg aataacagct tgagattgtg aatcttttag tttacatatt
     1621 attgaaaatt atgcaaagaa tttatggtcg cgattcaaag cttgcatggg gtatgctgaa
     1681 aggttagact atatttcaaa agtgccatgt aaggctttgg ataatcctaa agggaaacat
     1741 cccgacactc cattttggac ttatattgag tttcagaatt ttataaaatc gtttgatttg
     1801 caagattatg aagagctaca aagatttaca actatttggc tatattatat gacaggtgtt
     1861 cgtgtaagtg aaggtttatc attatgatgg gaaaatatcg atttcgaaca aaaattcttg
     1921 aaagttcata caaccttgga aaaggatgaa aatggaaatt ggtatcgtaa agaccaaaca
     1981 aaaacgccag caggagaacg tcttattgag ttagatgatg tgacaatagt attattggaa
     2041 aattggagaa gaaatcaagt agtcaatact gacacagatt tcattatttc acggtttggt
     2101 gaaccatttt gtaaatcaac gatttgtcga gttattaagc acaaagctca agaagtagga
     2161 gtaccagtga taacgggaaa aggcttgcga catagtcatg cttcctatct tattaatgtt
     2221 ttgaaaaaag acattctgta cgttgcaaag tgtatgggac atgctgataa gtctacaact
     2281 ttgaatacat atagtcactg atttaacgca ttagataaaa cagtatctga agaaataacc
     2341 caaaatgtaa taagttcagg attagattcc attttatacc aaaattcctg ccaaacaact
     2401 aattgatata acgaagctta ttatatcgcc catataacag gatgtgttat tgttacaggg
     2461 tacttgcttt atgagcttgt ttaagctact aaaggtgtgt gccactatac ttcattccaa
     2521 atttctgaga atttttgcta taatagtaac tatgaaagat ataatgataa aaaggtgggt
     2581 tgtccttttt tttatggtat taacttgttc agggtttggt aaaacagttc tcgcagctga
     2641 ttttcaagtg ggagcagaac atgcgattgt cgtagaggca gactctggga gagttctgta
     2701 tgagaaagac gctaagacgc cagatgctat tgcctctttg accaaattgg tgacggctta
     2761 tctggtttta gataaggtta aatcaggcca gctgcaatta tcagatcaag ttaatctctc
     2821 agattatgcc ttcgagttaa caaaagatag gtctttaagt aatgtacctt ttgacaaaaa
     2881 aacttattca gttcaagacc tgttgacagc tactttggta gcaagctcaa atagcgctgc
     2941 tattgcgttg gccgaaaaag tggcgggctc agagcctcat tttgtaaatc aaatgagaga
     3001 acagctatct cattggggga ttacttctgg taaaatcctc aacgcctcag gtctgccaaa
     3061 tgaggtgtta aaggaccatc gttatcctgg ttctgcgttg gaagaagaaa ataccttgag
     3121 tgctcaagat gttgcagttg tgacgatgca tttgttagaa gattttcctg agattttaga
     3181 gatcaccaaa caaacagaag ttaattttgc tggcaattct attaaaagtt ttaatcaact
     3241 cttaccaggt atggctaagg gtagagcagg agtggatggt ttaaagactg ggacaacaga
     3301 cttggcaggt cattgtcttg tggtaacttc tattgaaaat ggtatgcgag tgattaccgt
     3361 tattctaaat gccgatggat ctgataaaaa ccaaaacacg cggtttgagc aagcaaatcg
     3421 tttgttggac tatgtggcta gaacttattg tcgtcgtaag attcttaaaa aaggaagtct
     3481 tgtcttggag cggtcgctcc ctattcaaga tggccaagta aaagaactac cggtatccgt
     3541 tgccgaagat gtaaccatca ttttgcaaca gggtgaacaa gttcccaaac ctaaacaatt
     3601 tatgatatca gagactcctt tactagcacc gattactaaa ggtgaagtgg ttgcttattt
     3661 gacgtctcca agaataacag atcagtcagt gaggtattta aaggaaccta agcgtattcc
     3721 tcttaaagct agccaatctc taaaaaaagc ctctgactta cagctgtggt ggcgagattt
     3781 tcttgaaaaa agacgttaaa gataagaata aaataatttt aaaacaatca aaaaaagaca
     3841 gttatgaaag aattttttca taactgtctt tttagtttac agtgagtatg atttggaatg
     3901 ataaaaaaat tgatgttatg gttccattgt ttgtaaaaga ttttcaggac tcatgtttgg
     3961 gaggatacga atccggttaa gagaaagaag tccattagcc gcgctagcta ttccttcgtt
     4021 agtggtaaca cctaatttat agttaagtct agctgcaatt tgtaaggtag tgtcattata
     4081 tctaccagat ggataagcaa tggcaatagt gttttggttt aattgcttat caagatagtc
     4141 ctttgaatct ttcatttcag ttgtttgaac atcaggacta gcctgctcta gatcaggatg
     4201 attcactgta tgatcttgga aagacatacc gaattgtttc atttctttca tctgcttaag
     4261 agtcagattg gcagcgcttc ccatttcggt tagtcctgta ataacattat tggtggcttt
     4321 agcatcatat ttttttaaga ttgggtaagc aacgttgtag aaatcaatca tactgtcatc
     4381 aaatgttagc catacaactt ttttagcagg caattcatta tttgaaagag cgcggtagac
     4441 ctcttcagga ctcaaaaaat agtagccctc gtctttcatt ttttgaagtt gttgatcaaa
     4501 gagatctggg ttgacaatca aattagcatt agccgtctct tcaggggaca ttacatgaat
     4561 agcatgatac attaaaattg ggatcttgac aggtgtttct tgcttggtcc aagttaattt
     4621 agaatgggcc tttttttgag attttgagga atcgaaatga gtcttcttaa gttttgtcgt
     4681 ttcttttttt gccgtctttt tgtgatgaaa aagacttatt ttaggtacaa attgagagac
     4741 atctgacaag ccgaatttgt tagacccttg gtataaatag aaaatgaggg tcaaaccaag
     4801 aatgcaggca aataatagta taaggttaat gagagtgaag gcttttcttt tttggcgccg
     4861 tttatgtcta ttgttcatta cttgctcctt tttttgatat aagtacctct attgtaacat
     4921 tttttagaga aaagaaggct tgaagtcagc cttttttctt gttttttgga agaacgtgta
     4981 ttaaggagta aaaaaatatt gtcacagata acactttagg aggtagcaaa gactatgtgg
     5041 ggctggtatt cttatcacgt aaaaaaagca atgaagataa aagtgtagtg tactttagaa
     5101 cttatttgag tgtttggtga ggataataaa aaaagggtac tactctaggt tatctgctgt
     5161 cacttttttt tatatatggt atactaaaga tagatgtgag gtatgaaatg acttatgaag
     5221 agactctaga atggattcat gatcacttag ttttcggcat caagccaggc ttaaaacgta
     5281 tgctttgggt tcttggacag ttaggaaatc cccaaaaaaa tgtcaaggga gtgcatatcg
     5341 ttggaactaa cggaaaaggt tccacggtta atcatttaca acacatcttt acgacagctg
     5401 gttatgaagt ggggaccttt acctctcctt atattatgga tttcaaagaa cgtattagca
     5461 taaatggtcg aatgatttca gaaaaagatt tggttattgc tgctaatcgt attcgtcctt
     5521 tgacagagcg tctagttcaa gagactgatt ttggagaggt aactgaattt gaagtgatta
     5581 ctttgatcat gttcctctat tttggtgata tgcatcctgt agatattgct attattgaag
     5641 caggccttgg cggtctttat gattcgacca atgtttttca agcaatggtt gtggtctgtc
     5701 cctcaattgg tttagatcac caagctattt tgggagagac ttacgctgat attgccgccc
     5761 aaaaagctgg tgttttagaa gggggcgaga cccttgtttt tgccgttgaa aacccgtcag
     5821 ctcgagaggt ttttttaaca aaagctgagc aggttggtgc ttcaatctgg gaatggcaag
     5881 agcagtttca aatggctgag aacgcatctg gctatcgttt tactagtcct ttaggagtta
     5941 tttcagatat tcacatcgct atgccaggac accaccaagt gtctaatgca gctttagcta
     6001 ttatgacttg cttaaccttg aaagaccgct attctaggct aacttcagat catataaggg
     6061 aaggtctagc aaatagtttg tggctaggcc gtaccgaatt attagcacca aatctaatga
     6121 ttgatggggc tcataacaat gaaagcgttg ctgctttggt agccgtctta aaaaataact
     6181 acaatgataa aaagcttcat attttgtttg gtgcgatcga caccaagcct attgcagata
     6241 tgttggttgc tcttgagcaa ataggtgact tgcaggttac tagctttcat taccctaacg
     6301 cctatccatt ggaaaaatac ccagaacgtt ttggtagggt tgctgatttc aaagatttct
     6361 tggccttgcg taagcatgct aaagcagatg actttttcgt gattacaggg tcactatatt
     6421 ttatttcaga aattagacgg tattggaaaa aacatattga aaaaagcgtt cttttaaccc
     6481 attaaaaaag agaaaatgaa aaggaaaagg aaaaaactaa tgaaaaggga aagactaatg
     6541 tctattaata aggaaaaagc agaagcagcc atttatcagt ttttagaggc tattggtgaa
     6601 aatccaaatc gggaaggtct tcttgacacg cctaaacggg ttgctaaaat gtatgcggag
     6661 atgtttttgg gactgggaaa agatcctaaa gaggaattta cggctgtctt taaagaacaa
     6721 catgaggatg tggtgattgt caaagacatt agtttttatt ctatatgtga acaccactta
     6781 gttccttttt atggcaaggc tcatattgct tacttaccaa gtgatggtcg agtaacaggt
     6841 ttgagtaaat tagcgcgagc agttgaagta gctagtaaac gacctcaact ccaagagcgt
     6901 ttgacctctc aaatagcgga tgctttagtt gaagccctca atcctaaagg gactttagtt
     6961 atggtagaag cagagcacat gtgcatgacc atgcgaggca tcaaaaagcc aggtagtaaa
     7021 accattacca ccactgccag aggcttatat aaggaaagtc gtgctgagag gcaagaagtt
     7081 atttctctaa tgacaaaaga ttaggagaac ttatgaaaat tggaaagttt gtgattgagg
     7141 gcaatgcggc tatcatgggg attttaaatg tgactccaga ttctttttca gatggggggg
     7201 cttacactac tgtgcaaaaa gcattagatc acgttgagca aatgattgct gatggtgcta
     7261 aaatcatcga cgttggtgga gaatcaacac gtccaggttg ccgttttgta agcgctaccg
     7321 atgaaattga ccgggtggtt cctgtgatca aggccatcaa agaaaactat gatattctaa
     7381 tcagcattga tacctataaa accgaaacag ctagagcagc tttagaggcg ggtgccgata
     7441 ttctcaatga tgtttgggca ggtttgtacg acggacaaat gtttgcctta gcagccgagt
     7501 acgatgcgcc tatcatcttg atgcataacc aagacgaaga agtttatcaa gaggtaacac
     7561 aagacgtttg tgattttcta ggcaatagag cacaagcagc tcttgatgct ggcgtgccaa
     7621 aaaacaatat ttggattgat ccaggatttg gatttgccaa atctgttcaa cagaatacgg
     7681 agttattaaa aggattggac cgcgtctgtc agttgggcta tcctgtcttg tttggtattt
     7741 cgagaaagcg tgtcgtagat gccttgttag gcggcaacac caaagctaaa gagcgagacg
     7801 gagcgacagc agccttgtct gcttatgccc ttggaaaagg ctgtcagatt gtacgggtgc
     7861 atgatgtcaa ggctaatcaa gacattgtgg ctgtgttgag ccagttgatg tgaggactta
     7921 tggataaaat cgtattagaa ggctgccgtt tttatggcta ccatggagcc tttaaagaag
     7981 aacagaccct tgggcaaatt tttctggttg atttagaatt gtcagtcgat ttgcaagcag
     8041 cttctttgtc agaccaatta acagatacgg tccattacgg gatggtgttt gatagtgtcc
     8101 gtcagttagt ggaaggggaa aagtttattt tgattgaacg tttagcaggt gcaatttgtg
     8161 aacagctttt taacgaattt ccgcctattg aagccatcaa agtggccatt aaaaaggaaa
     8221 acccaccgat tgcaggccac tataaggcag ttggtattga attggagaga cagagatgac
     8281 cattgtttat ttaagtttag gcaccaatat gggggaccga gcagcttact tgcaaaaagc
     8341 tcttgaggct ttagctgact tacctcaaac acggttgctt gctcaatcat ccatttatga
     8401 aacgactgct tggggcaaga caggccaggc tgattttctc aatatggcct gtcaattaga
     8461 tacacaatta accgcggctg atttcttaaa agaaacacaa gctattgagc aatctcttgg
     8521 tcgtgtgagg catgaaaaat ggggatcaag aactattgac attgatatct tgctatttgg
     8581 agaagaggtt tatgacacaa aggaattgaa agtgccacac ccttatatga ctgagcgtgc
     8641 ttttgtttta atccccttat tggaattgca gccagattta aaattgcctc ctaatcataa
     8701 gtttttaagg gattatcttg cagctttaga tcaatcagat atcacactct tttcagctca
     8761 acagacagag ttctagactc tgttttcgaa gtaatgcctg ctataagcca atccataaag
     8821 ttttgccaaa ttcatcgtta ttttttctaa aatttgatat aatagtatcg gctttatgcc
     8881 gattttttta cgcgtataag aagtgataaa agaaagaaga taactatgat aactgaactt
     8941 catgggattg atattcgaga gaatgaaccc ctaaaacatt acacttacac taaggtaggt
     9001 ggcccagcag atttcttggc ttttcctaga aatcactacg agctatcacg catcgttgct
     9061 tatgccaaga aagaaaatat gccttggctt gttttgggaa atgccagcaa tctcattgtg
     9121 cgagatggtg gtattcgtgg ctttgtcatc atgtttgata agctaaatgc agtgcactta
     9181 aatggttata ccttagaagc cgaagctggt gccaatctga ttgaaacaac gaagattgcc
     9241 aaattccata gtttaacagg gtttgaattt gcatgtggca ttcctggaag cattgggggt
     9301 gctgttttta tgaatgcggg tgcttatggt ggggaaatat cacatatttt cttatccgct
     9361 aaggtgctta ccccaagtgg agagatcaaa accatttcag ctagggatat ggcttttggt
     9421 taccgtcact ctgccattca agaaacaggt gacattgtca tttctgctaa gtttgctctt
     9481 aagccgggta attatgatac gatcagccaa gaaatgaatc ggttaaatca ccttcgccaa
     9541 ctaaaacaac ctttagaatt tccatcttgt ggatctgtgt ttaagcgccc gccaggacac
     9601 tttgcaggtc aattaatcat ggaagcaaat cttaaagggc atcggattgg tggtgtggaa
     9661 gtttccgaaa aacacgctgg ttttatgatt aatgtggcag atggcacagc taaagattat
     9721 gaagatttga ttgcttatgt cattgagaca gttgaaaacc attctggtgc caagcttgaa
     9781 ccagaagttc ggattattgg ggaaaacctg taaccattat tgataattaa agaaagtacc
     9841 gtggaggatt tatgacaatt gactaagcca attatcacat ttaacaatgt ttcaaaaaca
     9901 tttgaggaca gtggaacaca ggttctaaag aacattaact ttgaccttga agaaggaaaa
     9961 ttttacaccc tgcttggagc ttctggctct ggaaaatcaa ctattttaaa tattatggcg
    10021 ggcctactag atgccagcag cggagacatt tatttagatg gggaacgtat taatgatttg
    10081 ccgattaata aacgtgacat tcataccgtt ttccaaaatt atgccctctt ccctcatatg
    10141 actgtttttg agaatgttgc ctttgctttg aagctgaaga aagtggacaa gaaagagatt
    10201 gctaagcgcg tgagagaaac cttgaaaatg gttcaattag aagggtatga aaatcgttct
    10261 atccagaagt tatctggtgg tcaacgtcaa cgtgttgcca ttgcgcgtgc gattatcaat
    10321 caaccgcgtg tggtcttact tgacgaacca ctctcagccc ttgatttgaa attaagaaca
    10381 gagatgcaat atgaattacg tgaattgcaa caacgtctag gcattacctt tgtttttgtt
    10441 actcacgatc aagaagaagc cttggccatg agtgattgga tttttgtcat gaatgaaggt
    10501 gaaattgttc agtcgggaac accagtggat atttacgatg agccaattaa tcattttgtt
    10561 gctaatttta ttggagaatc taatattatt aacggtacca tgattgaaga ctatcttgtc
    10621 tcctttaacg ggaaagaatt tgaatctgtg gacggtggaa tgcgccctaa tgagcctgtt
    10681 gaagtggtta ttcgtcctga agatcttcaa attactttgc cagaagaagg gaaattacaa
    10741 gttaaggttg atacccaatt attccgcggg gttcactacg aaattattgc ctatgatgaa
    10801 ttgggtaatg aatggatgat tcattctacc cgcaaagcta tcgagggaga agttatcgga
    10861 ttagacttta cccctgaaga tcttcatatc atgcgtctta atgagactga agaggaattt
    10921 gatgcccgta ttgaagaata tgtggaaatg gatgagcctg aagatggatt gattaatgcc
    10981 attgaggagg agcgtaatga agaaaacctc tagtcttttt tcgattcctt acttcttatg
    11041 gattctcttt tttgttgtgg caccagtcac tctcttgttt tacaagtcct tttttgacat
    11101 agaagggcgc gtgaccttag ccaattatga aacctttttt agctcttgga cttatttgag
    11161 gatgagtgtg aattctattt tatacgctgg tattatcaca ctcgtcacgc tcttgatttc
    11221 atatcctacg gctctctttt taacgcgcct aaagcacaag cagttgtggc ttatgctcat
    11281 tattttgcca acttgggtaa acttattgct aaaagcctat gcctttatgg gaatctttgg
    11341 tcaacaagga gggattaaca gctttttaac ctttatgggg attggcccgc agcaaatcct
    11401 tttcacggat ttctccttta tttttgtagc ctcttacatt gagctccctt ttatgatgtt
    11461 accgattttt aacgctttgg atgatattga ccataatgtc atcaatgcca gtcgcgacct
    11521 aggagctagt gaatttcagg ccttctcaaa agttattttt cccctttctt taaatggggt
    11581 tagggcaggt gttcagtctg tctttatccc aagtttgagt ctctttatgt taacccgttt
    11641 gattggtgga aaccgcgtga ttacacttgg tacagccatt gaacaacatt ttttgaccac
    11701 ccaaaactgg ggaatgggat caaccattgg tgtcgtcttg attttgacca tggttgctat
    11761 tatgtggctc acaaaggaga aaagtaaatg aaaaaatttg ccaatcttta tttagcgagt
    11821 gtctttgttt tactctacat tcctattttt tatttgattt tctattcttt caacaaaggt
    11881 ggggatatga atggttttac aggatttacc cttgagcatt accaaaccat gtttgaggat
    11941 agtcgtctca tgacaatctt actgcaaacc tttgttcttg cttttagtag cgctctacta
    12001 gcaacgatta ttgggacctt tggagctatc tttatccacc atgttagagg taagtaccaa
    12061 aatgccatgc tatcagccaa taatgtcttg atggtatcac cagatgtcat gattggggct
    12121 tcctttttaa ttctttttac atcattgaag tttcagctgg gcatgtcttc agttttatta
    12181 agtcatattg ctttttcgat tcctattgtg gttttgatgg tattgccgcg cttgaaagag
    12241 atgaatcagg acatggtcaa cgccgcttat gatttgggag ctaattattt ccaaatgctc
    12301 aaagaagtca tgctgccata cttaacacca gggattattg caggttattt tatggccttt
    12361 acctattcct tagatgattt tgcagtgact ttctttttga ctggaaatgg ttttactact
    12421 ttatctgttg agatttattc gcgggctcgt cagggaattt ccttggatat caatgctttg
    12481 tcaaccatcg ttttcttttt ctccatcctc ttagtgatcg gttattatta tatgtcacag
    12541 gacaaggagg aaaaacatgc gtaaacttta ttcctttcta gcaggagttt tgggtgttat
    12601 tgttatttta acaagtcttt ctttcatctt gcagaaaaaa tcaggttctg gtagtcaatc
    12661 ggataaatta gttatttata actggggaga ttacattgat ccagctttgc tcaaaaaatt
    12721 caccaaagaa acgggcattg aagtgcagta tgaaactttc gattccaatg aagccatgta
    12781 cactaaaatc aagcagggcg gaaccactta cgacattgct gttcctagtg attacaccat
    12841 tgataaaatg atcaaagaaa acctactcaa taagcttgat aagtcaaaat tagttggcat
    12901 ggataatatc gggaaagaat ttttagggaa aagctttgac ccacaaaacg actattcttt
    12961 gccttatttc tggggaaccg ttgggattgt ttataatgat caattagttg ataaggcgcc
    13021 tatgcactgg gaagatctgt ggcgtccaga atataaaaat agtattatgc ttattgatgg
    13081 agcgcgtgaa atgctagggg ttggtttaac aacttttggt tatagtgtga attctaaaaa
    13141 tctagagcag ttgcaggcag ccgagagaaa actgcagcag ttgacgccga atgttaaagc
    13201 cattgtagca gatgagatga aaggctacat gattcaaggt gacgctgcta ttggaattac
    13261 cttttctggt gaagccagtg agatgttaga tagtaacgaa caccttcact acatcgtgcc
    13321 ttcagaaggg tctaaccttt ggtttgataa tttggtacta ccaaaaacca tgaaacacga
    13381 aaaagaagcg tatgcttttt tgaactttat caatcgtcct gaaaatgctg cgcaaaatgc
    13441 tgcatatatt ggttatgcga caccaaataa aaaagccaag gccttacttc cagatgagat
    13501 aaaaaatgat cctgcttttt atccaacaga tgacattatc aaaaaattgg aagtttatga
    13561 caatttaggg tcaagatggt tggggattta taatgattta tacctccaat ttaaaatgta
    13621 tcgcaaataa gcactcaaaa aggctggtat ttctccagcc tttttaatgt atcgacagat
    13681 gacgtcacca gtacacgcga tagggacggc caaccttggt aaaaatttgt tggctgttca
    13741 gttgcttatt ttcttctaaa taagcaatgt atttacggac agagacatgg gataagtgac
    13801 aagcggaagc taattcttgg atagtaaaag gttgatcaaa ggctttgata ttttccataa
    13861 tccactggaa agtggattca gataagcctt tttctaacaa ttgtttgttt ttagtgtctt
    13921 ttttgctagt caaacatttc agttggtcaa tttgggcctg ctctagttgc tgattggcca
    13981 aatgttctcg atgtgtaaca aactgttgga tgctttcttg aaagcgttca aaggtaaagg
    14041 gcttgatgag gtagtcgata attcctaaat gaaaaccatc tcggataata ttcccatcat
    14101 ttgcggctga aataataatg acttcgcaag gaatatgctg agcacgccat ttctccaaaa
    14161 attgaatccc attgccatct gtaatatgaa tatccagtaa aatgaggtca attgcgtaat
    14221 cagtaagtat actttgaaca gctttcatag agtcgctgga tataatgcga tcaaaaagat
    14281 ttagtttttc gaggtaattg cgatggataa aatccaccat aggatcatct tcaatgatta
    14341 aaacgttcat gttgccctcc tacataaggt gttgtcactg agaactgtaa ctcggttacg
    14401 gtttgatgtt gatggaattg ggaatttgta tcggtcaaga gctgttgaaa ataaggtaag
    14461 tcaaaaatag gctgtacccg ctccaaatca atccaattgt ctgtcaaggt gtaatggctg
    14521 attaaatgat tctgatcatg ttgaatactc aaaacgagtg atttgggtct cagtgtggtt
    14581 agaagattag tatggataaa gcggtaaatc atcaaaccat tattaagttg attcttggtg
    14641 gcagaatgag gaatctcgct taaaacatca atcttgagat ggacatttaa ttcttggtat
    14701 ttctcttgct ctccaatgag aaaactagct agaagaggct ccttaacaag gacagataag
    14761 ctagtgagaa tttcattttc gggctccaaa atactgtcta aataaatttt caattggtca
    14821 taataagcaa tatccactaa gccataaata acatgcaatt gattcatgaa tttatgagtt
    14881 tgggcttgta gagcagaagc ataggcagtg gtataggcta gctgatccaa ggtatcaata
    14941 gccttaactg cttctcgcat gaaaataatg tggcctcggt gatcgttttt gacacagatg
    15001 ggtgaaatgg ctaacaagta gtcttcctca ccataccgaa agagttgttc atgcccctct
    15061 tgcaaactaa gttttggaaa atcaggaaag aggtgattga aactgttgcc agtaggtttt
    15121 cccaactggc atttccgagc aattaatttt tgtccagcct gattgcagag ctgtaagata
    15181 ccagctttat ctaccacaaa tacggcggct tcgatttgat ccaacatggc attacgctct
    15241 tcaaagagct ggtaaatttc acttggttct aactggtgca gttgacgctt gagtcgaaaa
    15301 gaaataacac tggtgaccag taaactaata agaagacaaa ggagtaaaga cagggtataa
    15361 ttgcgttttg acgttaaagc cacatcattt agggtagtta gtttaatgcc aaccgcaata
    15421 gcaccaatct gtttgtcacc gtcaaacaca ggtactagat agcgaagtga ctttcctaaa
    15481 gtgcccttgg cggtagagat aacctttttt cctgctagaa cagcctcctc atcacctcct
    15541 tgaaaaggtt ttccgatatt tttcgggtta ggatgggtga gtcgaatccc tttcatgttc
    15601 atcacgacca cataatcaag gttatagatg gaggcaatgg agttggtata ggctgttgtt
    15661 ttagcatttg gttggttgtt taggagtaat tctttaattg cttgatgact tgctaacatt
    15721 tttccagttg acgttagcaa atgggtttcc tgatttttga tggattggtg cgtatcatgt
    15781 agcataatcc cgtaaaatag agaggttgtg acaacaatca tagataccaa aatcaacgat
    15841 aaactggccc ataaacgtag tggttttttc ataaggtctc ctctttattg agtataacac
    15901 gataagaaat gacctgctag cttaaattaa ttaaataact tgaaaaaatt aaagtagtta
    15961 aacaacttaa ataaactatg cttttgacat gttctctttt atactagcct tatcactaaa
    16021 ggaggttgtt tcatggaaac aataagcaag aaaatgcctc aaaaagactt gtctgagcat
    16081 tcaaaagcat ggcaaaatag gcgaataggc tccgttccgt tgcctgttta tctggtttta
    16141 gctaccttaa ttttagtcac aggctggctc caacaattgc ctgttaatat gctgggtggc
    16201 tttgctgtta ttttaaccct tggttggcta ctaggaacca ttggagcgac cattccaggc
    16261 ctcaaacatt ttggtggccc agctatttta tcactcttag tcccttcgat tttggttttt
    16321 tttaatctcc tcaatcccaa tgtcttagaa gcgacgaatg tcttgatgaa gcaagccaat
    16381 tttctttatt tttatattgc ctgcctggtc tgcggtagta ttttaggcat gaatcgaaaa
    16441 atcttgattc aaggactctt tcggatgatt attccgatgt tacttggaat ggtttgtgct
    16501 atgggagtag ggactttggt tggcgtcatt ttaggattag actggcaaca taccctcttt
    16561 tatgttgtga cgccagtcct tgctggagga attggtgaag gtattttacc cttatctctt
    16621 ggttacagtg ccattacagg agtcggaagt gagcaattag tggctcaact gattccagcc
    16681 accattattg ggaatttctt tgctatcttg tgcacggctt tgctcaatcg ttttggagag
    16741 aagcacccaa gttattctgg tcaagggcaa ctggttaaga ttggtcacag cgaagacatg
    16801 tctgatgccc taaaagacaa ttctggagcc ctagatgtta aattaatggg ggcaggcgtt
    16861 ttaacagctt gttcactttt tattgctggt ggcttgttac agcatttaac aggttttcca
    16921 ggaccggtgt tgatgattat tctggcagcc ttcttgaaat acctgaatgt tattccccaa
    16981 gaaacccaaa atggtgccaa gcaactttat aaattcattt ccagcaactt tacttttccg
    17041 ttaatggcag ggcttggtct gctttatatc cccttaaaag aggttgtggc aacccttagc
    17101 tggcaatatt ttattgtggt gattagtgtg gtgttaacgg ttgtcagtgt cggttttttt
    17161 gtctctcgtt tccttaacat gaacccagtg gaagcagcta ttatttcagc ttgtcaaagt
    17221 ggtatgggtg gaaccggtga tgtggctatt ttgagtaccg ctgaccgcat gaatctaatg
    17281 ccgtttgccc aagtcgctac ccgtttaggt ggggctatta ccgttatcac tatgacagct
    17341 attttaagaa ttatttttag ttaatccaaa ccaataaaaa agagaggtat tccctatgga
    17401 aaatcaatta ggtcaacttg cccttgaaca agccaaaacg ttcggcggta aattggaagt
    17461 tcaaccaaaa gttgacatta aaactaaaca tgatttgagc attgcctata caccaggtgt
    17521 agcgagtgtg tcatctgcca tcgcaaaaga taaaacatta gcatatgact taaccaccaa
    17581 gaaaaataca gtagccgtta tcagtgatgg tactgcggtt cttggtctgg gggatattgg
    17641 ccctgaagca gccatgccag ttatggaagg aaaagcagcc ctttttaaag catttgcggg
    17701 tgtcgatgct attccgattg tattagatac caaagatact gaagaaatta ttagtattgt
    17761 caaggcgctt gcaccaacct ttggtggtat taatttagag gatattagtg cgccccgctg
    17821 ttttgaaatt gagcagcgct tgattaagga atgtcatatt cctgttttcc atgacgatca
    17881 gcatggaaca gctattgtgg tgttagcagc catcttcaat agtttgaaac ttcttcaaaa
    17941 atctcttgat gaggtatcca ttgtggtgaa cggtggtgga tctgctggat tatccattac
    18001 ccgtaaatta ttagcagcag gtgctacgaa agtgacagta gtggataaat ttggcattat
    18061 caatgaacaa gaagccgctc aattagcgcc acatcatttg gatatagcga aagtcactaa
    18121 tcgtgagttt aaatcaggta ccttagaaga tgctcttgaa ggagcagata tcttcattgg
    18181 cgtatcagca ccaggagtct taaaagcaga gtggattagt aaaatggcag cgcgcccagt
    18241 aatttttgcc atggccaacc ctattccaga gatttaccct gatgaagccc ttgaagcggg
    18301 ggcttacatt gtaggtactg gccgcagtga ttttcctaac cagattaata atgtccttgc
    18361 ctttccaggt atttttaggg gagcattaga tgcacgggca aaaaccatta ctgttgagat
    18421 gcaaattgct gccgcaaaag gtattgccag tcttgtccca gatgacgctt tgagcactac
    18481 taatattatt ccagatgcct ttaaagaagg agtcgctgag attgtcgcta aaagcgtcag
    18541 gtcggtagtc cttaaatcat agaatatatg aaaaaaagag aaagttatac tttaaatcac
    18601 aaaataagta gaagcatatt tctagcttct acttattttg tgattagcta atatcattat
    18661 caataataac tttcaaggcg ttatttgcac cagcatgttt aaaggtttca taagcttttt
    18721 caacttctga aagtttaaaa tgatgtgtaa taagtcttgt tgcgtcaatc tttccagttt
    18781 tcaagacatt tagtagcatt tcagttgtat tggcattaac aagtccagtg tttaaggtga
    18841 tatttttaat ccataattca tccaggttga aatcaactgg tttcccatga accccaacgt
    18901 tagcaatatg cccacctact gatataattt tttgacaaat atcaaatgtc gcgggataac
    18961 caacacactc catggaaata tcgacaccac gtccattggt tatatcgtca atgatagcct
    19021 tgacttcttc actacttcct gaacaaatcg tgtgtgtggc tccaaatgtt ttagctgctt
    19081 caaggcgatt ttgagataag tcgaccataa taatattggc tggagagaaa aattgaacgg
    19141 ttagtagggc tgcgagtcct actggaccgg caccaacaat acaaacatta tctccaggct
    19201 tgacatgtga tggcaagaca ccaatttcat atgaagttgg taaaatatca gaaagcatga
    19261 caagtgcctc atcatcaatc gtatcaggag catgatagag actaccatct acatgtggga
    19321 tatggacata ttctgcttgt gttccattaa ttaaatggcc aagaatccaa ccgccatctt
    19381 cacaatgtga cgaaaggcct cgtttacaat aataacaggt atgacatgat gtgacgcaag
    19441 aaataatcac tttatctccg attttaaagt tagtaaccgc atcaccgacc tccttaacaa
    19501 ttccaattcc ttcatgacca agaattgttc cttctttaca tgcgggaaca tccccaccta
    19561 agatatgcaa atcagttcca caaatagtgg tttttaccaa ctggacgata gcatctgtag
    19621 gctttataat gactggtttt ggtttgtcta tgagctgtag atttccggtt gaaaggtaag
    19681 ttgctgcttt catatttaat tccttataag gttgagaggt aatcaaccaa ttcattttta
    19741 cacagatatt ataatagttt aagaaagggt tttcaatatt ttttaaatcg attatgataa
    19801 ttttttagat catctttgtt gaataacttc atccttattc agaacttaaa gggtactatt
    19861 ataagaattt gaaaccgctt tacttaaacc gtgtattttt gtacaataat gattaaggag
    19921 gtttttagat gaaaaaagaa tttaccagta tcctgtttac agttagtttt tgtggaatca
    19981 tagcattgcc tgtcgaagct agtggcccta aagttcctta tacacaagaa ggtataacgg
    20041 ccatttcaaa tcaggcaaca gtaaaattga tttctattgc tgatatcgcg agcagtttag
    20101 aaggacaaaa acctataacg gttagttttg atatcgatga tactttgtta tttactagcc
    20161 aatattttca gtacggcaaa gaatatataa ctccaggctc atttgatttt ttgcataagc
    20221 aaaaattttg ggacttggtc gctaaacggg gagatcagga ttctattcca aaagagtatg
    20281 caaagcaact aatcgcaatg catcaaaaac gaggagataa aattgtcttt attactggcc
    20341 gaactcgagg atcgatgtat aaaaaaggtg agattgataa aacagctaag tcactggcta
    20401 aagattttaa gttagacaag ccaatagcta tcaattatac aggagataaa gctgtgaagc
    20461 cgtatcagta tgataaaaca tattatataa agaaaaacgg ctcacaaatt cattacggag
    20521 atagtgatga agatataaat gctgccaaag aggcaggtgc aagacctatt cgcattttaa
    20581 gagctcctaa ttcaaccaat cttcctttgc caaaagctgg aggatacgga gaagaggttt
    20641 tagaaaattc ggcttattag tcaaatattt gtgtaagaaa ggaagtaaca gtaatttctt
    20701 tcatcacccc actgagtaac caatagccca gtgggttttt tgggttacag aaatcagttc
    20761 taaaaaagaa tcactggtaa cttaaggttg tctttgatac aatggtaaca gtgtatttaa
    20821 aagaaagaga ggacaacatg gaaaaccata aaaatgaatt caccttttcc aacaaatcaa
    20881 ttattgccta tgtttggcgt ggtgttgtgg ttggtattat tgctggtgtt attgttagtt
    20941 tattccggtt gttaattgaa gtgacagctg actgggtgat tgaatggtac cgatacgctc
    21001 atatcaattc gctgttgcta cttcctatac taagtgtcag tttgttagct gttctttttg
    21061 taggtttttt agtaaagtct gattctgata taaaaggatc agggatcccc catgtcgaag
    21121 gagaactaaa ggggctaatg tccccagatt ggtggagtgt cctttggaaa aaatttttag
    21181 gaggaatcat ggctatttct atgggattta tgctcggtcg tgagggtcct tcgattcagt
    21241 taggtgctat gtcagccaaa ggattagcta agtttttaaa atcgagtcgt ttggaaaagc
    21301 gagtgctaat tgccagcgga gcagcagcag ggctatcagc agcttttaat gctccaatag
    21361 caggcctctt gtttgttgtt gaagaaattt accatcattt ttcgcgttta atttggatta
    21421 cagcgctagt ggctagctta gtggctaatt ttatttctct gaatattttt ggattgaaac
    21481 cagtcttagc aatgtcagag gcgatgcctt ttttaggact caatcaatat tggttgttgc
    21541 ttttacttgg attatttcta ggctgcttag gctatttata tgagatagtt atccttaatt
    21601 ttaataaact ttatgttatt ttagggagtt ggttacatct gccagcttat ttttacggta
    21661 ttattatggt ttttctaatt ttaccgattg gctattattt accacagtta cttggaggag
    21721 gacatggttt aatactttct ttatccaatc aacaattgcc tttgatgact atcttctttt
    21781 attttattat tcgatttatt gttagtatgt ttagttatgg aagtggctta cctggaggta
    21841 tttttttacc tattttaact ttaggtgctt tggcaggcct attatttggg caaatagctt
    21901 ctcaattagg tttattgaac caatcttttc tttctctttt tttgatatta gggatggcag
    21961 ggtattttgc ggcaatttca aaagcaccac tgacaggcat gattttggta actgaaatgg
    22021 taggtgattt gaaaccctta atggccatag ctgtagttac ttttgtctcc tatttagtga
    22081 tggatttgtt aaatggacag ccaatttacg aagctatgct agataagatg gcaatgaagc
    22141 atccaactaa tcttgttgaa ccaacattaa ttgaattgac tgttggtgat aagattgcag
    22201 ggaaatatgt taaagagtta aagcttccag aaaatgtctt aattacaacc caaattcacc
    22261 atcaaaaatc tcaagttgtg tcaggtaaca cgcgcctttt atcaggagca actatctttt
    22321 tggtcgttaa tgaagctgat acaggttttg tccgtgaggt attgatgtag gtattaattt
    22381 atcacaattc ggaaagttcg agcttgtctt ttagactaag tcttcgaacg ttttactgct
    22441 agagtttcat ctgaaccaaa gtgaaacgct tttgatgaag tcaagtaggc tttttgttat
    22501 actaacaata aagataagct aaggaggctg agatgttaga aattgtttca gaagagctac
    22561 gtcactatca agaacaaaaa ttgattgagt accgtaacaa aaatcagtta gccccaaaag
    22621 gaggcattgt atttgcaggt gattctctca ttgaattttt tcctttaaaa aaagcttttg
    22681 gttcatgttt gcctattatt aatcgaggta ttgctgggat agatagtcag tggttattgc
    22741 gccatttttc tgtccaaatt actgatttag agcctaaaca tattttttta ttaattggtt
    22801 gtaatgatat cgggcttgga tatgataaat gtcatattgt caagactatt gtagagctta
    22861 ttagccagat tcgtagtcat tgtgtctaca gtcagattta tctcttatct ttattaccag
    22921 tttccaacaa tccccgatat cagaagactg tcaaaataag aacaaatgct atgattgatg
    22981 ctattaataa agatttagca atgattccaa ctatagaatt tattaatctt aatacttgtc
    23041 ttaaagacga aaaaggtggt ttatcagatg agaatactct agatggttta catcttaatt
    23101 ttccagctta tgctaaacta gctgaaatta ttcaagctta tatctagcaa ataaatgtac
    23161 taatagcgat gaggcaagaa gtcagatagc agatggttca tcaatcaatt aagaaaaaag
    23221 ttatcaagat accattaaaa atagttgctc aaagttcttt caaatcaaaa gattatgata
    23281 tcgctatgtt gagttttagt gtataatgat aattaaagga gttaccatga aatttgaaaa
    23341 aaaacaagtc ttctatttag tccttacgtt tatcttatgc tatgggatcc tagcaaactg
    23401 gcgaaatgga acggctatcg ttacgactat ttacaaaaca agccttcctt ttttttatgg
    23461 agcagcaggt gcctatattg ttaatattgt aatgagcgct tacgaaaagg tatatgttta
    23521 tatctttaaa gactggtcac atgtcttaaa agtaaaacgg ggtatttgtt tactgttagc
    23581 gtatttgaca ttttttattt taattacttg gattatttcc attgtcattc cagacttaat
    23641 tacaagtatt agtactctaa caaaatttga tactataacg atacaagaag ttgttaacaa
    23701 tcttgagcac aataaactgt tagcacgtac tattcagtat attggtggcg atggcaaact
    23761 tacagagacg attgctaact atagtcaaca gttattaaag caatttctta ctgttttgac
    23821 aaatatttta acatctgtca cggttattgc ttctgcaatt attaatcttt ttattagttt
    23881 tgttttttcg ttatacgttt tagcaagtaa agaagatctt tgtcgtcagg gaaatacttt
    23941 agtagatact tatactggta agtacgctaa acgcattcat tacttgttag agttgttgca
    24001 tcagcgtttt cacggatttt ttgttagtca gaccttagaa gctatgattt taggttcgct
    24061 gactgctagt ggcatgttta tattaagatt accatttgca gggactattg gcgttttagt
    24121 agcttttaca gcattgattc cagttatagg tgcttcaatt ggagcagcta ttggatttat
    24181 tttaattatg actcagtcca tgtcacaggc cattattttt atcatttttt taattatttt
    24241 gcagcagatt gaaggcaatt ttatttatcc gaaagtagtt ggtggatcga ttggattacc
    24301 ggctatgtgg gtattaatgg caattacaat aggcgcttct ttaaagggaa tagttggtat
    24361 gattattgca gttcctttag cagcgacact ttatcaagtg attaaagata atattcaaaa
    24421 aagacaagct attcaaaaaa aacaagtttc ctaaaaggaa cttgtttttt tgtcgaataa
    24481 aaagatggag gtaatatgat aaatgtattc tataaaatgt gatgataata aagccatgcc
    24541 aagagaacgt ttgatgcgac taggagcaga gtctctaagt aatcaagaat tattagcaat
    24601 tttattacga acaggtaata aagaaaagca tgtcttagag ctgtcatcct atcttttatc
    24661 gcatttagac agtctggcag attttaaaaa gatgtctttg caagaattac aacatttggc
    24721 aggtatagga aaagttaaag cgattgaaat taaagctatg attgagttgg tttcccgaat
    24781 tttagcgaca gataagacat taactgatag cgtattaacc agtgttcagg tcgctgaaaa
    24841 aatgatggca gctttaggag ataaaaaaca agagcattta gtcgtattgt atttagataa
    24901 tcaaaatcgt attattgaag aaaaaactat ttttattggg actgtccgac gttcacttgc
    24961 agaaccaaga gaaattttat actatgcctg taaaaatatg gcgactagtc tcattgttat
    25021 tcataatcat ccttcaggaa atattgaacc tagttctaac gattattgct ttactgaaaa
    25081 aataaaacga tcatgtgaag atttaggcat tatctgtcta gatcacatta tcgttagcta
    25141 taaagattat tatagttttc gagaaaaatc aacccttttt taaatcagaa gtcattgacg
    25201 aataagcgga acaattgtag atcttcatct cgaacacctt ggagaagttc aggatgccac
    25261 tgaacaccta aaaaaggaat ggcatcgttg gttgatatga ctgcttcgat ggtaccatca
    25321 cgtggatctc tagcgattac ttttaaatcc ttagcaacag tttttaaact ttggcgatga
    25381 aaagaattaa ttaatgtctt atgaccgtaa ataggatata agacagagtc tggctcaata
    25441 atcatttcgt gtgataagaa atcagaaggc gcttcttgcc aatgtgagtc aatgtgttgg
    25501 ttaagatttc ctcctaaggc aacattcatt aactgtgtac cacgacaaat ccctaagatt
    25561 ggttttttaa tgttatagcc tccttgatga tagctagctc aaatgtgtct cgctctggtg
    25621 aaaaatcatc atcaaaagca gccttctctt cttgataata ttttgggtca acgttttgcc
    25681 caccaattaa aatgatttta tcaaccatag atacataagt tttagcggcg acttcatcac
    25741 caatgggtaa aagaagcggc agccccccag attgagtgac tgcctgtaca aatccagtag
    25801 gtgcatatga ccatgggaga ttatccaaag ccatatttag tctttgattt gcagttattc
    25861 caataatcgg tttggtcatt atacctcctt aatctagatg attttgattc ataaaataga
    25921 gtagtgtctg gagctcactg gtcaaatcga cagattgaac aataactcct ttaggaactt
    25981 gtaggtgaac aggagcaaaa ctcaagattc ctttgattcc tgcttcaata agttgatcag
    26041 taacttcttg agcatgaatg ctgggaaccg ttaagatagc cgtttcaatg tcagtattcg
    26101 taatccgttc tttgacagat gagataccat ggactggaat attatcagct gttttagtac
    26161 caacaagagc gttatcatcg gtatcaaaac ccatggcaat ttgcatctta ttacgatcat
    26221 ggaagcggta atgtaataga gcacgcccta tattaccgca tccaactaag ataacgtttg
    26281 ttgtagagtg atcattaagc aagtcagcaa aaaaattcat caatttggta acatcatagc
    26341 caaacccacg acgccccaat tctccaaaat aagaaaagtc acggcgtaca gtagcagagt
    26401 caattcccat tgcatctgca atttgtttag aactggcttt ttcaacttgg tcagcatgga
    26461 atcgtttaaa aatacggtaa taaagtgata agcgctttgc agtcgctttt ggaatagatt
    26521 tgtcaataac cactatttta ctccttgtag atttctcgtt aaatatgtct gtctttattg
    26581 taacaaaaag attgtgaaaa atgcaacatt ttgattgttt ttgtatgagt taaaaaagct
    26641 aaaattagtt ttagcactat ataatagtat tcattaggaa agtaagttat gacagtcaaa
    26701 atgaacaaca tgaattaata gcaatagaag cgaaatcatt tattgacatt gtgatatgac
    26761 taaaaaacaa aatttaaagt tgattagacg actgttttgc taaaaatttc acgttctaca
    26821 aggctgtcca tcaagaaata aaatttatct
//
LOCUS       DATTYN010000023        26499 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.23, whole genome shotgun sequence.
ACCESSION   DATTYN010000023 DATTYN010000000
VERSION     DATTYN010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26499
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.23"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..629
                     /locus_tag="VB649_001259"
     CDS             <1..629
                     /locus_tag="VB649_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1670209.1"
                     /translation="EMILQGIVAFLSEYDYTVITAKDGEQAIEYFKRHIIHLIILDVM
                     IPKKNGFEVLLEIKRERDIPIIVLSAKEDEETQVKAFELGADDYVTKPFSLLLLVSRI
                     KTILKRYCVVDELWQYQNTTVDFSTHCAYYKGQEVKIRPKELAVLQCLVKYKNQVLSR
                     EQILEQVARDVADLPYDRVVDVYIRKLRKNLNLDCIKTVKNVGYKISL"
     gene            1465..2862
                     /locus_tag="VB649_001260"
     CDS             1465..2862
                     /locus_tag="VB649_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEP1670210.1"
                     /translation="MACTTILVGKKASYDGSTMVARTEDSQNGDFTPKKMIVVKPEDQ
                     PRHYRSVQSSFEMDLPDNPMTYTSVPDALGKDGIWAEAGVNEANVAMSATETITTNSR
                     VLGADPLVASGIGEEDMVTLVLPYIRSAREGVLRLGAILEDYGTYESNGVAFSDGHDI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGIDHFEFNNPEDYLCSADLKDFIDTYHLDL
                     TYSHEHFNPRYAFGSQRDKDRHYNTPRAWIMQKFLNPEIVQDPRSFALAWCQKPYRKI
                     TVEDVKYVLSSHYQDTVYDPYGSEGTPVSKKVFRPIGINRTSQTAILHIRPNKPQEIA
                     AIQWMAYGSMPFNTMVPFFTQVKTIPDYFANTYENVSTDNFYWTNRLIAALADPHYNH
                     HETDLDNYLEETMAKGHAMLHAVEAQLLAGETVDLEEENQKMSDYVQGETQTLLNKIL
                     FDASNLMTNRFSLSD"
     gene            3014..4561
                     /locus_tag="VB649_001261"
     CDS             3014..4561
                     /locus_tag="VB649_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEP1670211.1"
                     /translation="MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEF
                     TKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSL
                     TSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRS
                     ITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAA
                     FGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTL
                     AKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTK
                     TVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKD
                     YYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEA
                     KEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREI
                     AQEINAH"
     gene            4709..5431
                     /locus_tag="VB649_001262"
     CDS             4709..5431
                     /locus_tag="VB649_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP1670212.1"
                     /translation="MPKEQPLYLQIVDDLEVKIKKSMTENDKLLSERELSDLYGVSRI
                     TIRLALKELELRDLIYKKQGKGTYVSGIKEPATDLSSTYSFTEQMKKMGKTPKTEILS
                     FEQYQVTPYLSGLLELDPDTEVFELERLRIADDMPLMFERSYIPAQLFQGLSIEHLKR
                     KPMYDLFAEDYQETIRLAEEDFYASIALDYEADLLGIKKGDPVLHIIRKTYNDKNILI
                     ELTFSIARADQFRYRVQHHPNG"
     gene            5450..6649
                     /locus_tag="VB649_001263"
     CDS             5450..6649
                     /locus_tag="VB649_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEP1670213.1"
                     /translation="MFTKTQEALEALGAAITTKEIKQEPRLWQETMTFFEETRDSLDS
                     FLKRVCNSANRNNVHVIFTGAGTSEYIGNTICPYLKKVGNRQCYLFESVASTDLVAAP
                     DYYLVEEETVLLVSFARSGNSPESVAAVNLVNQLVPNSYHLTITCAKDGELAKKAQQD
                     ERSYLYLMPEDANDAGFAMTGSFTCMMLAALLIFDDANSIAQKEAYVTDMILAGQAVI
                     DQERRLQELADLGFERLVYLGSAGLAKLTQEAQLKMLELTAGQVATLYESSMGFRHGP
                     KSFINDRTLVIGFVNNDAYVRQYDLDMLEEIQADGIALKTLALLQGGDINFSEDQFRL
                     DTRHLLPEAYLAFPMILVAQTLALLTAVTLGNSPDTPSATGTVNRVVKGVTIHPYPTS
                     SRQCNKA"
     gene            complement(6746..7006)
                     /locus_tag="VB649_001264"
     CDS             complement(6746..7006)
                     /locus_tag="VB649_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEP1670214.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(7121..8062)
                     /locus_tag="VB649_001265"
     CDS             complement(7121..8062)
                     /locus_tag="VB649_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEP1670215.1"
                     /translation="MITTFETILDKIKAHQTIIIHRHQNPDPDALGSQAGLKEIIAQN
                     FPDKKVLMTGFDEPSLTWISQMDQVTDKDYKEALVIITDTANRPRIDDERYTLGQCLI
                     KIDHHPNDDVYGDFYYVDTSASSASEIIADFAFSQNLTLSDKAAKLLYTGIVGDTGRF
                     LYASTTSKTLSIASQLRHFEFDFAAISRQMDSFPLKIAKLQSYVFEHLTIDESGAAYV
                     LISQETLKHFDVTLAESSAIVCAPGKIDNVQAWAIFVELTDGNYRVRMRSKEKIINGI
                     AKRHGGGGHPLASGANSANLEENQAIFRELIAVCQEI"
     gene            8456..8905
                     /locus_tag="VB649_001266"
     CDS             8456..8905
                     /locus_tag="VB649_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEP1670216.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVDIDECTTVDAS
                     EFENADIAVVATYTYGDGDLPDEIVDFYEDLQDLDLEGKIYGVVGSGDTFYDYFCKSV
                     DDFSEQFALTGAIKGAEPVKVDLAAEDEDIDRLEAFAEQLSQAVNNL"
     gene            9081..9365
                     /locus_tag="VB649_001267"
     CDS             9081..9365
                     /locus_tag="VB649_001267"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEP1670217.1"
                     /translation="MRLEEIRQEINSIDHHLVALLEKRMALVEQVTAYKLANHLPVLD
                     QARENQILDRVSYLVKDQAFEPAIHETFKTIMSLSRQYQTQRLTGGDTND"
     gene            9358..10620
                     /locus_tag="VB649_001268"
     CDS             9358..10620
                     /locus_tag="VB649_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HEP1670218.1"
                     /translation="MIKSIATLPKPSLKEALGLIGLALPIGATVGVVDVIFGKGLLFL
                     SEYRDHHLFLLLPFLALAGLVIVFLYDKLGKEVRQGMGLVFQVGHGQKDQIPPILIPL
                     ILFSTWVTHLFGASAGREGVAVQIGATISHYCQRFVTSQEAARHLLIMGMAAGFAGLF
                     QTPIAAVVFALEVLLVGMLRYCALLPSLVAACAASWTSHSLGLEKFTIVLEETLTITP
                     LTLVKLIGLGLIFGLVGNSFACLLGWFKPYLSQKLPNPYLRIAFIGVLLSICLMIGHV
                     GRYSGLGTHLIAAAFSGQTILTYDWLLKMIVTVISLSAGFQGGEVTPLFAIGASLGIV
                     LAPYLGLPVLLVAALGYVTVFGSATNTFWAPIFIGVEVFGPENALAYFVTSAAAYMVS
                     HRHSIYSYQKVVMINLKDMTVNQMDLKK"
     gene            10735..11082
                     /gene="rplS"
                     /locus_tag="VB649_001269"
     CDS             10735..11082
                     /gene="rplS"
                     /locus_tag="VB649_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEP1670219.1"
                     /translation="MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            11329..11400
                     /locus_tag="VB649_001270"
     tRNA            11329..11400
                     /locus_tag="VB649_001270"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11362..11364,aa:Arg,seq:cct)
     gene            12097..12666
                     /locus_tag="VB649_001271"
     CDS             12097..12666
                     /locus_tag="VB649_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEP1670220.1"
                     /translation="MKGMNYQDYIWDLGGTLLDNYELSTQAFVQTLAFFSLPGDHDAV
                     YQKLKESTAIAVAMFAPNEPEFLHVYRLREADKLAQPIWSLGAKEILEKIATSGSRNF
                     LISHRDCQVNQLLEQAGLLIYFTEVVTASNGFARKPNPESLFYLKEKYDINSGLVIGD
                     RLIDKQAGQAAGFNTLLVDGRKNLLEIVT"
     gene            12667..14619
                     /gene="gyrB"
                     /locus_tag="VB649_001272"
     CDS             12667..14619
                     /gene="gyrB"
                     /locus_tag="VB649_001272"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEP1670221.1"
                     /translation="MIEENKHFEKKMQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIKVFIEADNSITVVDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGQIHYQEFKRGAVV
                     ADLEVIGTTDVTGTTVHFTPDPEIFTETTQFDYSVLAKRIQELAFLNRGLKISITDKR
                     SGMEQEEHFHYEGGIGSYVEFLNDKKDVIFETPIYTDGELEGIAVEVAMQYTTSYQET
                     VMSFANNIHTHEGGTHEQGFRAALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDANQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGIDQEDQ
                     LKTALEKYSIGRSKPTVQRYKGLGEMDDHQLWETTMDPENRLMARVTVDDAAEADKVF
                     DMLMGDRVEPRRDFIEENAVYSTLDI"
     gene            14987..16711
                     /gene="ezrA"
                     /locus_tag="VB649_001273"
     CDS             14987..16711
                     /gene="ezrA"
                     /locus_tag="VB649_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEP1670222.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQAL
                     FALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFN
                     FIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASIS
                     ENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRAREENAHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKD
                     EIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSI
                     KTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFL
                     SAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQL
                     LQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYE
                     KTREHIRF"
     gene            complement(16843..17301)
                     /locus_tag="VB649_001274"
     CDS             complement(16843..17301)
                     /locus_tag="VB649_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEP1670223.1"
                     /translation="MTNLEDKLLKGAWGERRLNPEQQRYYLGTYAERVVLSALLDEAQ
                     TKTVKDYLKRELPSLQLVYQPLHLKISFKLAPQLQILYMKLAKENHLPVTIITETHMT
                     SPFAFILHTDHAINLKETRLEVILKQTKNDQLSKQTPEKTKSFWKRFLKK"
     gene            17534..18841
                     /gene="eno"
                     /locus_tag="VB649_001275"
     CDS             17534..18841
                     /gene="eno"
                     /locus_tag="VB649_001275"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEP1670224.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQV
                     DYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIK
                     ENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(19316..20345)
                     /locus_tag="VB649_001276"
                     /pseudo
     CDS             complement(19316..20345)
                     /locus_tag="VB649_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677767.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(20612..22153)
                     /locus_tag="VB649_001277"
     CDS             complement(20612..22153)
                     /locus_tag="VB649_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP1670225.1"
                     /translation="MLHLHLETKLQDKLSLLNILLDVSEVSIDQLCQETELKKQRVYN
                     LLIEMIKDLEDTLTLTICDDIVSIPYKTYQLKMPYFKKLYQTSIFLKMLCFLIEPGEL
                     SLHDFIKREYISQATAYRIRTNCRKYLKKVGLNVRQNHVVGPEYRIRFLIALLHYQFG
                     MTIYDFDKTSMNKVVSLIINSNQAITLNDASKAPYEFSYFAILISLIWKRRHDNLGIP
                     QTDAFKHLKKLSIYHDIKMTSQEIIGKWYHPDLTDEDLDYIFLCFCTTNNPFHKDKWT
                     PKKVKELFELVMTKTIGKTLKASLRPLLGNNILNSLPFKRILVSFSRLFISNLQVLLP
                     DIHLFHYLRRQQKRNKSFYNTLKTIVEEWMSAEGIVGKLPSYHLLLFTIQLEELLKTY
                     LPPIPVYLLTNNTAALDLMTNALSIYFPPAIATVMPVNVEIIPFKDIVKEKQSVIIAD
                     RQYLNLIQHLYQNQGHLFLYFLFSFRDVSEAYIHKAFLDFRQKRYDEFIVTLLDTYHK
                     NLSSP"
     gene            22625..>26499
                     /locus_tag="VB649_001278"
     CDS             22625..>26499
                     /locus_tag="VB649_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEP1670226.1"
                     /translation="MFLKHQDVKQKNWRMRKVKKLFVSSCMLLTVGLGVAVPTAFSQS
                     NGVMVVKAAEVPATDLSRQASDSERVDESSLLQKENLSVDSFKLENLNGWEAENDTAG
                     NLGKFKDPDSSGYQNILTSSGKNISVAVAPKGSGKMNIKVTKRSNFQGGYYVGGLRTQ
                     TPVLKLNDVYRYSFTTKKLSGNSSEFKTRVKPVESNNKLGKELVIRVDNKNVSTKHDW
                     LPDISDGTHTVDFTGLDKKLSVAFRFSPRQTSNVVYEFSNINIKNISPASVPAIPSKV
                     LEGTSVLSGTAISSGDTLEKRKSFDGDILRVYKDSKIIARTVIKGNKWDVKLSKPLIA
                     GEKLDFEILHPRSQNVSKKISKQVEAKPFDPASYKEKVIAKLKPVYEATSEKITNDAW
                     LDENAKDLQKQKLEEQYISGKVAISEAGTKQEAIDAAYNKYSSQTDPDSLPSQYKQGN
                     KENEQEKGRQDLIQTRDLTLKAIQEDKWLTEQEKTTQKEEALKAFETGIESVNQTVSL
                     EQLKQRLIVYKASEKDSEKKEYPESIPNQHIPGKEKEVKAAKQEELKKLHDTTLEKIN
                     QDKWLTPDQQAEQLKQAEVTFKKGQEAIKSAQTLTQLETDLADYVSENEGKGNSIPDK
                     YKSGNKDDLVNKAEVKLKEAHEATKQAIEKDPWLSPEQKKAQKENAKARLDAGLKAVE
                     TTESLDKLKEVESDFLDKEKAKSIPSQHQAGTPEVARKTFLDNFEKEAQKELESIKND
                     VTLTDAEKATAKAKVEAQLQEAKDKAKESKSFDDLKNIQDKFNSELPHTTGKPLKDQQ
                     SDAIAELEKKQQEIEKAISEDKTLSKDEKEKQIADSKAKLVAEKEKVSKAPDADAVKK
                     ALESGKQEIAKAYVPQNLEDHKKKLLAELKQKANDTEKAIDFDKTLTAKEKEEQKAKT
                     KEELQKATEAVGAIDNREELDKKVPELKKAIQDSHVKGDLEGVKNKAIEDLQKVHDET
                     VAKINGDDTLDKATKEAQVKEADKALAAGKDAITKADDADKVGAAVTEHTPKIKAAHK
                     TGDLKKVQEEANQALDKAAEKEREEINNDATLTTEDKAKQLKEVETALTKAKDNVKAA
                     KTADAINDARDKGVATIDAVHKAGQDLGARKSGQVAKLEEAAKATKDKISADPTLTSK
                     EKEEQSKAVNAELKKAIEAVNAADTADKVDDALGKGVIDIKNQHKTGDPVVARREAHG
                     KQLDRVAQETKDAIEKDPTLTTEEKAKQVKDVDAAKERGMAKLNEAKDADALDKAYGE
                     GVTDIKNQHKSGDPIEARRGLHNKSIDEVA"
BASE COUNT         8638 a         4517 c         5485 g         7859 t
ORIGIN      
        1 atgaaatgat tttgcaggga attgtggcat ttctcagtga atatgattat actgtaatta
       61 ccgctaaaga tggggagcaa gctatcgaat attttaaaag acacataatt cacttgataa
      121 tactggatgt tatgatacct aaaaagaacg gattcgaagt cttattagaa attaaacgag
      181 aacgagatat tcctattatc gtcttgagcg caaaggaaga cgaagaaaca caagtgaaag
      241 cttttgaatt gggagctgac gactatgtga cgaagccatt ttcattgcta ctcttagtaa
      301 gtcgaataaa aacaatttta aaacgttact gtgttgtgga tgaattgtgg caatatcaaa
      361 atacgacagt tgatttctcg actcattgtg cttattataa gggacaagaa gtaaaaatta
      421 ggccaaaaga attagctgta ctacaatgtc ttgttaagta taaaaatcaa gtgcttagtc
      481 gcgaacaaat tttagaacaa gttgccagag acgttgctga tttgccttat gatcgagttg
      541 ttgacgtcta tattaggaaa cttagaaaaa atctaaatct agattgtatc aagactgtta
      601 agaatgtggg atataagatt agcttataag tttcacaatt atagaatatt tacaaaaata
      661 ttcattaaaa tatttcttat tatgagagca gttaatctcg ctattcatat tgaggtatgc
      721 gtttctttca tgttaaaaga gaaataagta ctactgtacc tgcaaagtat cttgaaacaa
      781 aaacagaatc ggagatttct aatgcccttg aagatcattc taaatcaata gatgtttcgg
      841 tccatttaga gcgagatatt actaatgaat ttattgctaa agggaattgt aaaatcttct
      901 atgttctaag tatggaaaaa atatggaaga attgaaagtt tataaagtag taacggatgt
      961 cttagattat tataatgagc tggtgagaat tataaattaa aaatacagaa tatattgtct
     1021 ctatcagcag aactatggat gaattgtaaa gctttagata aagtattatc aaatataatt
     1081 gtaatgttaa caggtataca aagaatgatg gctgcattct cataaatgag aaagcaggct
     1141 acttgattat ttcaaatcga tattttttat catgctcaag taacaacttc taaacaggaa
     1201 gaggctaatt tggggctata cattttaaaa atatttttgc gagtttctca ccagaacgat
     1261 tatgtttttc ggatatctaa atataatatg gaacttaaaa taaagttaac aaagacagtt
     1321 atctaaaaca aaacactata atcttatgag cctttattca taagattttt tctgtctaaa
     1381 agtcgttttc cattgttttt ttgaagtgtc tgatgttctg tgatatgata aaagggataa
     1441 taacgtttgt aaaggagact gataatggca tgtacaacta tactcgtcgg taaaaaggca
     1501 tcttatgatg gctcaaccat ggttgctcga acagaagatt ctcaaaatgg agatttcacg
     1561 cctaaaaaaa tgattgtggt gaaaccagaa gatcaaccga gacattaccg ttcggtgcaa
     1621 tcttcctttg aaatggactt accggacaat cccatgactt acacgtctgt tcccgatgcg
     1681 cttggtaaag atggtatctg ggcagaagca ggcgtgaacg aggctaatgt ggccatgtca
     1741 gcaactgaaa ccatcactac caattctcgt gttttagggg cagatcctct agtagcttct
     1801 ggtattggtg aggaggacat ggtgacctta gtgctccctt atatccgttc tgcgcgtgaa
     1861 ggggttttgc gccttggtgc tattttagaa gactatggca cttacgagtc aaatggtgtg
     1921 gctttttcag atggacatga catttggtgg ctggaaacga ttggtggtca ccactggatt
     1981 gcaagacggg tgccagatga tgcttatgtc accaatccca atcaatttgg cattgatcat
     2041 tttgaattta acaatcctga agattacctt tgctcagctg atttaaagga ctttattgac
     2101 acgtatcact tagatttaac ctatagccat gaacatttta atccgcgcta tgcctttggt
     2161 agtcaacgtg acaaagaccg tcactataat acgccacgtg cttggatcat gcaaaaattc
     2221 ttaaacccag aaattgtgca agacccgcgc agctttgccc ttgcttggtg tcaaaaacct
     2281 taccgtaaaa taacagtaga agatgtcaaa tatgtattga gtagtcacta tcaggacacg
     2341 gtttatgacc cttacggttc agaaggaact cctgttagta agaaagtctt tcgccctatt
     2401 ggcattaacc gtaccagcca aaccgctatc ttacacattc gtcctaataa acctcaagaa
     2461 attgccgcta ttcaatggat ggcttatggg tcaatgccat ttaataccat ggtgcctttt
     2521 ttcacacagg tgaagactat tccagattat tttgccaaca cttacgaaaa tgtgtctacc
     2581 gataattttt attggaccaa tcgcttgatt gcggctttgg cagatcctca ctacaatcat
     2641 catgaaactg atttggacaa ttatttggaa gaaaccatgg caaaaggtca tgccatgtta
     2701 catgctgtgg aagcacagtt attggctggt gaaacagtcg atttggaaga ggaaaatcaa
     2761 aaaatgagtg actatgtgca aggagaaacg cagacgctgt tgaacaagat tctctttgac
     2821 gctagcaatc taatgaccaa tcgtttcagt ttgagcgatt aaaagtgaag ctaaggctga
     2881 gcaactgctt agcctttttt gcgataactt tttaggaaaa gtaatcgcaa aaagacaaaa
     2941 acttggaaaa aaaatcaaag tatgctatac ttaactggtc aatttttaac cagttaataa
     3001 caaaggagga atcatgaaaa agaaaattct tttaatgatg agtttaatca gtgtcttttt
     3061 tgcttggcaa cttactcagg caaaacaagt cttagcagag ggtaaagtga aggtggtgac
     3121 aactttctat cctgtttatg aatttacaaa aggggttatt ggtaatgatg gcgatgtttc
     3181 catgcttatg aaagcaggaa cggaacctca tgattttgag ccttctacaa aagacattaa
     3241 aaaaatccaa gatgcagatg catttgttta tatggatgac aatatggaaa cttgggtttc
     3301 tgatgtgaaa aaatcattga catctaaaaa agtgaccatc gtcaagggaa ctggtaacat
     3361 gctcttggta gcaggagctg gacatgacca tcaccatgag gatgctgaca aaaagcatga
     3421 gcataataaa catagcgaag aaggacacaa ccatgctttt gacccacacg tgtggttgtc
     3481 accataccgt agcattacgg tcgttgaaaa tattcgcgac agtctttcaa aagcttaccc
     3541 agaaaaagca gagaacttca aagccaatgc cgctacttat attgaaaaat taaaagagct
     3601 tgacaaagac tatacggcag cactttcaga tgctaagcaa aaaagctttg tgacacaaca
     3661 cgcagctttt ggttatatgg cacttgacta tggcttgaac caaatttcta ttaatggtgt
     3721 cacaccagat gcagaaccat cagcaaaacg tattgctact ttgtcaaaat acgttaaaaa
     3781 atatggcatc aaatacattt attttgagga aaatgcgtca agtaaagtcg caaaaaccct
     3841 agctaaagaa gcaggagtta aagcggctgt gcttagtccg cttgaaggtt tgactgaaaa
     3901 agagatgaaa gctggccaag attactttac ggtcatgcgt aaaaaccttg aaaccttacg
     3961 cttaaccact gatgtggctg gtaaagaaat tcttccagaa aaagacacga ctaagacagt
     4021 ttacaatggt tatttcaaag acaaagaagt caaagatcgt caattatctg actggtcagg
     4081 tagctggcaa tctgtttacc cctacctaca agatggtact ttagaccaag tttgggacta
     4141 taaggctaaa aaatctaaag gtaaaatgac agcagctgaa tacaaagatt actacactac
     4201 tggttataaa actgacgtgg aacaaatcaa aatcaatggt aagaaaaaga ctatgacctt
     4261 tgttcgtaat ggtgaaaaga aaaccttcac ttacacatac gccggcaaag aaatcttgac
     4321 ctatccaaaa ggaaatcgtg gagttcgttt catgtttgaa gctaaagaac caaatgctgg
     4381 cgaattcaaa tacgttcaat ttagtgacca tgccattgct cctgaaaaag cagagcattt
     4441 ccacctgtac tggggtggtg acagccaaga aaaattacat aaagagttag aacattggcc
     4501 aacttactat ggttcagatt tatctggtcg tgaaattgcc caagaaatca atgctcatta
     4561 atcttaactc actaagcaaa tcttctttta aggaggtttg ctttttcttt gtggagtaaa
     4621 aaaatttaat aattctcaac attaatttga cggacactta tgattataat atactataag
     4681 tggttataac aagttagagg tgaataagat gccaaaagaa caaccactct atctacagat
     4741 tgttgatgac ttggaagtga aaatcaaaaa gagcatgaca gaaaacgata agttgttgtc
     4801 agaacgagaa ttaagtgacc tttacggtgt tagtcgtatc acgattagac tggctcttaa
     4861 ggaattggaa ttacgagact taatttataa aaagcagggc aaggggactt atgtttcagg
     4921 aatcaaagaa cctgccactg atttatcaag tacttacagc tttacagagc agatgaaaaa
     4981 aatggggaaa actcctaaaa cagagattct ttcttttgaa cagtatcagg taacacctta
     5041 cttgtctggt ctcttagagc ttgatcccga tacagaagtt tttgaattag aacgcctaag
     5101 gattgcagat gatatgcctt tgatgtttga acgatcctat attcctgctc agctttttca
     5161 agggttaagc attgagcact tgaagcgtaa gccaatgtac gatttatttg cagaggatta
     5221 ccaagaaact attcgcctag cagaagaaga tttttatgct agcattgcct tggactatga
     5281 agcagacctt ttgggaatca aaaaaggaga tcctgtctta catattattc gtaaaactta
     5341 taatgataaa aatatcttaa ttgaattgac tttcagcatt gcaagggcgg atcagtttag
     5401 gtaccgggtg caacatcacc ctaatggtta aggaattgga ggttaggaca tgtttacaaa
     5461 aacgcaggaa gctttggagg ctcttggtgc agctatcact accaaggaaa ttaaacaaga
     5521 accccgttta tggcaagaaa ccatgacgtt ttttgaagaa acaagagatt ctctggattc
     5581 ttttttaaag agagtttgta acagcgctaa cagaaataac gttcatgtca tctttacagg
     5641 tgcgggtaca tctgagtaca tcggtaatac catttgccct tacttgaaga aggtggggaa
     5701 tcggcagtgc tatctctttg agagcgttgc ttcaaccgat ttggttgcgg cgccagatta
     5761 ttatcttgtt gaggaagaga cggtactatt agtctccttt gctaggagtg gtaatagtcc
     5821 agaaagtgta gcggctgtta acctggtcaa tcaactagtg ccaaatagtt atcatttaac
     5881 cattacctgc gccaaagatg gagaactggc gaaaaaagca cagcaagatg agcgttctta
     5941 cctttatttg atgcctgaag acgctaatga tgctggtttt gccatgactg gtagttttac
     6001 ctgtatgatg ctagcggctc ttttgatttt tgatgatgct aacagtatag ctcagaaaga
     6061 agcttatgtg actgatatga ttcttgctgg gcaagctgtt attgaccaag aaagacggct
     6121 acaagagcta gctgatttag gatttgaacg tttagtttat ctaggttctg ctggtttagc
     6181 caagttaacc caagaagctc aattaaaaat gttagaattg acagctggac aagttgcgac
     6241 cctctacgag tcctctatgg gctttaggca tggtccgaaa tcttttatta atgaccgtac
     6301 cttagtcatt ggatttgtca ataatgatgc ttacgtcaga cagtacgatt tggacatgtt
     6361 agaggaaatc caagcagatg gcattgccct taaaaccttg gctctattgc aaggagggga
     6421 tatcaacttt tcagaggacc aatttcgact agacacccgt cacttattgc cagaagctta
     6481 cttagctttt cccatgattt tagtcgcgca gaccttggcc ctcttaacgg ccgttacatt
     6541 aggaaattcc cctgacaccc catctgcgac aggaacggtt aatcgtgtgg tcaaaggagt
     6601 aacgattcac ccttacccga ctagtagtcg tcaatgcaac aaagcttaaa gcttttgtgt
     6661 agaagccgta aaacgaaatg attttgtgct agtaggccaa aagaaaaacc ctcctgatac
     6721 aggaaggttt tttgtattgt cttgcttatt ttgctgcgtt tgcgtctttg agaccgtatt
     6781 ttttgttgaa gcggtccaca cgtccatctg cttgagtgaa cttttgacgt cctgtgtaga
     6841 atgggtgtga atctgatgaa atttccacac ggataagtgg gtaagtttca ccttcaaact
     6901 caacagtttc tttagaagct tttgttgagc cgctaaggaa ctggtaacct gtagttgtat
     6961 caaggaaaac aactggacga taatctggat gaatgtcttt tctcatctta aaaaattcct
     7021 ttctgccatg acacttaatg catcatagtt attaaccatt ctagtgtaac aaaacttgaa
     7081 tgacttgaca aggcttttct ttccttattt tttaaaaatc ctaaatctct tggcaaacag
     7141 cgatgagttc tcggaaaata gcttgatttt cttctaaatt agctgagttg gctccgctag
     7201 caaggggatg cccccctcca ccgtgacgct tagcaatgcc attaataatc ttttctttac
     7261 tgcgcatacg cacacggtag ttgccgtcag ttaactcaac aaaaatagcc caagcttgaa
     7321 cgttatcaat tttaccagga gcacagacaa tggcagagct ttctgctagg gtcacgtcaa
     7381 aatgttttaa ggtttcttgg ctgataagga cataagcagc cccactctca tcaattgtta
     7441 aatgctcaaa gacgtagctt tgcagctttg ctattttcaa aggaaacgaa tccatttgcc
     7501 ttgaaatcgc agcaaagtcg aactcgaaat gtctgagttg gctagcaatg gaaagggttt
     7561 tactagtggt tgaggcataa agaaatcgcc ctgtatcacc aacgatacca gtgtataaga
     7621 gcttagcagc cttgtcagag agagtaagat tctgactaaa ggcaaagtct gcaatgattt
     7681 cacttgcgct agaagcgctt gtgtccacat aatagaagtc accatacaca tcatcgttgg
     7741 gatggtgatc aatcttaatt aagcactgcc ccagtgtgta gcgctcatca tcaatccttg
     7801 gtcgatttgc tgtatctgta atgatgacca aagcctcttt atagtctttg tcagtcacct
     7861 gatccatttg gctaatccaa gttaaactag gctcatcaaa accagtcatc aaaacctttt
     7921 tgtctgggaa attttgtgca ataatttctt tcaagccggc ctgactacca agagcatcag
     7981 ggtcaggatt ttgatggcga tggataataa tagtttggtg agcttttatt ttatctaaaa
     8041 ttgtttcaaa agttgttatc atgctttaat ctttcttttt caaaaagagg aaaataaccg
     8101 tttaacatag tcttcaaaaa acggtttgtg tcataaggag gtgtgcgtta tgttaagtgg
     8161 ctaatgctag aattttttaa gattgtcaaa gaccataaat tgacatttta tctgaaaatc
     8221 atatcctatt ttattatagc ataaaagtaa gctctagata atggtaaatt aatctaggaa
     8281 gaaaagaggt tagttatcag ttatgatact atcaaagcta gtcttgcaaa tgcaagtgaa
     8341 aaaatagttt ttaagtgttt taagtaatca tatcaacctt ctcgttaaac aattagtgct
     8401 tttcctaaaa aagtgtgcta aaataaacat agtttagtaa ttttgggagg aatttatggc
     8461 attagcaaaa atcgtttatg ccagcatgac gggaaatact gaagaaatcg ctgatatcgt
     8521 tgcaaataaa ttgcaagaat tgggccatga tgttgacatt gatgagtgca caacagttga
     8581 cgcttcagag tttgagaatg ctgatatcgc tgtcgttgcg acttatactt atggtgatgg
     8641 tgacttacca gatgaaatcg ttgattttta cgaagattta caagatttag atttagaagg
     8701 taaaatctat ggcgttgtcg gctctggtga cactttttat gactattttt gcaaatctgt
     8761 tgatgacttt tcagagcaat ttgcgcttac tggtgccatc aaaggtgcag agcctgtcaa
     8821 agtagacttg gcagcagaag atgaagacat cgatcgttta gaggcctttg cagagcaact
     8881 ctcacaggct gttaataatc tataaaacta tttagtaaaa atgtcaggga cttccttggc
     8941 atttttagat ttttaaccta aaataaaggg aatgtcactt caggatagga attgaaaaaa
     9001 acaatcagct tcaccttgct tctgatcctc ttattaacta taataaaaag ataatctaat
     9061 acatctagaa aaggaaagtt atgcgtttag aagagatacg acaagaaatc aatagtattg
     9121 atcaccactt ggttgcctta ttagaaaagc ggatggcact tgtagagcaa gtaacagctt
     9181 ataaactagc caatcacttg cctgtcttag atcaggcgag ggaaaatcag atcctagata
     9241 gggtttctta tctcgttaaa gaccaagcat ttgagccagc tatccatgag acttttaaaa
     9301 ccattatgtc tctttcacgg cagtatcaaa cgcaacgctt aacaggtggt gacactaatg
     9361 attaaatcaa ttgcaacact gcctaaaccc tccttaaaag aagcgttagg actaataggc
     9421 ttggcgcttc ccataggggc cacggttgga gtggttgatg tgatttttgg taaagggctt
     9481 ttgtttcttt ccgaatatcg cgatcaccac cttttcttgc ttcttccttt tcttgcccta
     9541 gcaggtcttg ttatcgtttt tctttacgat aagttaggca aagaggttcg tcaagggatg
     9601 ggattggttt ttcaggtagg gcatggtcaa aaagatcaga ttcctcctat tctcattcct
     9661 cttattttgt tctcgacttg ggtaactcac ttatttggag cgagtgcggg tcgagaaggg
     9721 gtagccgttc aaataggagc taccatctct cattattgtc agagatttgt gactagtcaa
     9781 gaagccgcac gacacctttt gattatgggg atggcagccg gttttgcagg actttttcaa
     9841 acgccgattg ctgctgtcgt atttgccctt gaggttttat tagtaggaat gcttcgctac
     9901 tgcgctttat tgccttcctt agttgctgct tgcgcggctt cttggacctc tcattctttg
     9961 ggattagaga aatttacgat tgttcttgaa gaaacattga ccataactcc cttaacctta
    10021 gttaaattaa ttgggttagg tcttattttt ggtctggtgg gaaatagttt tgcctgttta
    10081 cttggctggt ttaaacctta cctgagtcaa aagctaccaa atccttatct caggattgct
    10141 ttcattggtg ttttgttatc tatctgtttg atgattggtc acgttggaag atatagtggt
    10201 ctagggactc atttgattgc ggcagctttt tctggccaaa ctatcctaac ttacgattgg
    10261 cttttaaaaa tgatcgtgac ggtgattagc ttatctgcag gctttcaagg tggtgaagtg
    10321 acgcctctat ttgctattgg agcttcttta ggcatcgttt tggcccctta cttaggtctt
    10381 cctgtactgt tggttgctgc acttggttat gtcacggtat tcggaagtgc aacaaatacc
    10441 ttttgggccc ctatctttat tggggtagag gtctttggtc cagagaatgc cctagcatat
    10501 tttgtcacct cggctgcagc ctatatggtt agtcacagac attccattta cagttatcaa
    10561 aaagtagtca tgatcaattt aaaagacatg acggtaaatc agatggattt aaaaaaatag
    10621 ctttacaata aagaagcttt ttgttagaat aaatctcgtg tgtaatggac acacgaaaat
    10681 tacggctaat ccgctaagac aagtacttaa gattagtaag ataggagaat aaaaatgaat
    10741 ccattaatcc aaagtttgac agaaggtcaa cttcgctctg atatccctaa cttccgtcct
    10801 ggtgacactg ttcgcgttca cgcaaaagtt gtcgaaggaa ctcgcgaacg tatccagatc
    10861 tttgaaggtg ttgttatttc acgtaaaggt caagggatct cagaaatgta cactgttcgt
    10921 aaaatctcag gtggtatcgg ggtagagcgt acattcccaa tccacacacc acgtgttgac
    10981 aaaatcgaag ttatccgcca cggtaaagtc cgtcgtgcga aactttacta cttgcgtgca
    11041 ttacaaggta aagctgctcg tatcaaagaa attcgtcgtt agtttgaacc gaaacgtaac
    11101 gtaatagaat aaaaagacta gagtctctag tctttttatg tcgtcgtgac aatgtgacaa
    11161 ttggtgatta acgctatgct cgtaggacac tttgaaagtt ccttagcagt tataattagt
    11221 atattgtaat aacaaaatga agcaaaataa acttttagtt atctgatatt tcatcttgca
    11281 ttaccttatt ttctaggtta aaatagaaga caaggtgaat ataagataga ccccttagtt
    11341 caatggatat aacaactccc tcctaaggag tagttgctgg ttcgattccg gcaggggtca
    11401 ttattgtcac tgaaaaagcc tttacatcaa aggctttttt gtattactca attaatgtta
    11461 ggagcacaaa agaggcagtt cgattattaa ccaattcctc cctatttaca gttgtatggc
    11521 tataaatgga caatcttaag ttagggtctg agtgactaaa cctgtcccta accgcttttg
    11581 gtggtaattc tttttcagct aaaagcgaaa tgtgcgagtg tttgaataag tgagtatggt
    11641 aatcaccata aatttttagg cgcttattga tgtgtgcatt taaaattggt aaaccttttg
    11701 aatatggaaa gctgttagca ctctgcttgt gattaatcta tcgtatgtta aaagtgacat
    11761 ttaaattaaa tcatttttta tacatatatt tcaacaggat ttatcatatt gggaaatagc
    11821 ggtgattcta ttggcatttt actattgaca ggaatttccc tgccttttgt ctcctaaaga
    11881 agatcagctt tgatttctaa cttgattaga gtgggcttgg tactgtttat gaattatcag
    11941 tacatacttt ctggaaatca aaaaggaaag gaacagctaa agaggtgtat gtgttaccat
    12001 tagaggaata gaacatcgca agactcgttt attcagtcat tacgatacct gttttatttg
    12061 ggaaataact ataatattaa gtgaatttgt gatataatga aaggtatgaa ttatcaagat
    12121 tatatatggg atttgggagg taccttactc gataattacg agctttcaac ccaagctttt
    12181 gtccaaacgc tagctttttt cagccttcca ggagatcacg atgctgttta ccaaaaatta
    12241 aaagaatcaa ccgctatcgc tgtggcaatg tttgctccta atgagccaga atttttgcat
    12301 gtgtataggc taagagaagc agacaaattg gcacaaccca tttggagttt gggagctaaa
    12361 gaaattttgg aaaagatagc gacttcaggt tcgcgaaatt ttttaatttc tcatcgagat
    12421 tgtcaggtga accaactttt agagcaagct gggttgctaa tctattttac agaagtcgtg
    12481 acagcttcaa atggctttgc tcggaaacca aatcctgaaa gtttgtttta tttaaaagaa
    12541 aagtatgata ttaatagtgg attagtaatt ggagatcggc taattgataa acaagcagga
    12601 caagcagcgg gttttaatac cttgcttgtt gatggtagaa aaaacctatt ggagatagta
    12661 acgtagatga ttgaagaaaa taaacatttt gaaaaaaaaa tgcaagaata cgatgccagt
    12721 caaattcagg ttctagaagg gctggaggct gtccgcatgc gtccagggat gtatattggc
    12781 tcgacagcta aagagggttt gcatcattta gtctgggaaa ttgttgacaa ctcaattgac
    12841 gaagcattag caggttttgc ctctcatatt aaagtcttta ttgaagcaga taattccatt
    12901 acagtagtag acgatggccg tggaattcca gttgacatcc aagccaagac aggacgtccc
    12961 gccgttgaaa cagtttttac agtcttacac gcaggtggta aatttggtgg aggcggctat
    13021 aaggtttctg gaggactaca tggtgtaggg tcatctgttg ttaatgcttt atcaacacaa
    13081 ttagatgtgc gtgtttataa aaatggtcag atacattacc aagaatttaa acgcggggct
    13141 gttgtagcag atcttgaggt cattggaacc actgatgtga ctggcacgac cgtacacttt
    13201 acacccgatc cagaaatttt taccgaaacg actcagtttg attacagtgt tttagcaaaa
    13261 cgtattcaag agttagcctt tttgaatcgt ggtttaaaaa tttccattac agataagcgc
    13321 tcaggtatgg aacaagaaga acatttccat tatgaaggtg gaattggttc ttatgttgaa
    13381 tttttaaatg ataaaaaaga tgttatcttt gaaacgccca tctatacaga tggtgaatta
    13441 gaaggtattg cagttgaagt agccatgcaa tacacgacta gctatcaaga aacagtcatg
    13501 agttttgcta ataatattca tactcatgaa ggtggaacgc atgaacaagg ctttagagcg
    13561 gctcttactc gggtcatcaa tgactacgct aagaaaaata aaattcttaa agaaaatgag
    13621 gacaatttga caggagaaga tgttcgtgaa ggtttgacgg cggtaatttc tgttaagcat
    13681 ccaaatcctc aatttgaagg tcaaaccaaa acaaaattgg gcaactcaga agtggttaag
    13741 atcactaatc gtctctttag tgaggccttt caacgttttc ttttggaaaa cccacaagtt
    13801 gctcgtaaga ttgtggaaaa agggattttg gcttctaaag ctagaattgc agctaagcga
    13861 gcccgcgaag tcacccgcaa aaaatcaggc ttagaaattt caaacttacc tggaaaatta
    13921 gcagactgtt cgtcaaatga cgctaaccaa aacgaacttt tcatcgtcga aggagattca
    13981 gcgggtgggt cggccaaatc aggtcgtaac cgagagtttc aagctatctt gcctattcgc
    14041 ggtaaaattt tgaacgtgga aaaagcaact atggataaga ttcttgccaa cgaagaaatt
    14101 agaagtctct ttaccgctat gggtacaggt tttggtgcag actttgacgt gtcaaaagct
    14161 cgctaccaaa agctggttat catgaccgat gccgatgtgg atggcgctca tattagaacc
    14221 ttgcttttaa cattgattta ccgctttatg aggcctgttc tagaagctgg ctatgtttat
    14281 atcgcccagc cacctattta tggtgttaag gtcggtagtg agattaaaga gtatattcag
    14341 ccaggtattg atcaagaaga ccaattaaaa acagctcttg aaaaatatag tattggtcgt
    14401 tcaaaaccaa ctgttcaacg ttataaaggt cttggggaaa tggatgacca tcaactttgg
    14461 gaaactacta tggatcctga aaatcgtttg atggcgcgtg tgacagttga tgatgccgca
    14521 gaagcagata aagtatttga tatgttaatg ggagatcgtg ttgaaccaag acgtgatttc
    14581 attgaggaaa atgcggttta tagtacactg gatatttagt caccttttta gtttcacaag
    14641 gaatctgcta ccaaagagga cgaattgact aaaaatcatg atgcatgatg ccaacagctt
    14701 tgttagttag tacgtcttca tcttgaggga cagcgttaat gcataggtat tgagatcgcc
    14761 ccttaatacc tgtgttagcc cttattaaga aagccttgtg agtcgctggt acgagattgt
    14821 tgaattagtc aaatatattt tgaaatgcat tttaaagtat gttataatcg taatgttata
    14881 gtgtatttta aataaaattt taataaaagg cgattgagga atttcagttt ttagttatta
    14941 ctggaacaat gttgataaat cgtgtctaaa taataaggag attcagatgt caagcggaat
    15001 tatcttgctg attgtggcta tagtcctact agtgattatc gcctatctag tgggtgtcat
    15061 catacgaaag cgtaatgatt ccctaattac cagtctagaa gaacgaaaac aggccttgtt
    15121 tgctttgcct gttaatgatg aaattgaaga agtaaagtca cttcatttga taggacagag
    15181 ccaaacctct tttcgggaat ggaatcagaa atgggtagac ttaactgtaa attcgtttgc
    15241 agatattgaa aatcatattt ttgaagctga aaatttgaat gatacgttta attttattcg
    15301 cgccaagcat gagattaata gcgttgaaag tcagcttaat cttgttgaag aagatatcgc
    15361 ttctattcgt gaagcactta atatcttaaa agagcaagaa gaaaaaaata gtgctcgtgt
    15421 cacccatgct cttgatttat atgaaaagct ccaagcttct atttctgaga atgaagataa
    15481 ttttggttca actatgcctg aaattgacaa acagatgaaa aacattgaaa ctgaattttc
    15541 acagtttgtc gcactcaact catcaggtga tcctgtagaa gcttctgaag ttctggatag
    15601 agcagaagag catactattg ctctagggca gattacagag cagattccag ctattgtggc
    15661 caagttggaa gatgattttc cagatcagtt agatgatttg gaaacaggat atcgccgttt
    15721 acttgaagaa aactatcatt ttccagaaaa aaacattgag gcacgttttc aggagattcg
    15781 tgagtctatt cgtgccaatt catcagagtt agttacactt gacttggatc gtgctagaga
    15841 agaaaacgcg catattcaag aacgcattga ttctctttat gaagtctttg agcgcgaaat
    15901 tgccgcttat aaggtagctg ctaaaaatag taagatgtta cctcgttacc tagcacatgt
    15961 gaaacgtaat aatgaacaac tcaaagatga aattgcacgt ttatcacgta aatatattct
    16021 aagtgaaacg gaaagtctta ctgttaaggc atttgagaag gatattaaag agatcgaaga
    16081 cagtacactt gctgttgcag aacaatttgg tttacaagaa aaaccatttt cagaactgca
    16141 agtgactttt gaacgcagta taaagacgct tactaatgtc gagtcaggtc aaatggatgt
    16201 ttttgcagca gttaaagata ttgaaaaaat tgaatcacag gcacgccata accttgatgt
    16261 ttatgttact cagcttcata tgattaaacg ttatatggaa aaacgtcact tgcctggaat
    16321 tccacaagac tttcttagtg ctttctttac aacgagttca caattggaag ctttgatgga
    16381 tgagcttagt agaggacgga tcaatattga ggcagtgtca cgtttgtcgg aagttgcgac
    16441 ggttgctatt gctaatctag aagatttaac ctatcaagtg gttcaaaatg ctaccttgac
    16501 tgaacaatta ctacaatatt ctaatcgcta tcgttctttt gaagcaggag ttcaaagtag
    16561 ttttgaacat gctttgagac ttttcgaagt agaaaatgat tatcaggctt cttttgatga
    16621 aatttcttat gctcttgaaa cagttgaacc tggggtaaca gatcggtttg ttaactctta
    16681 tgaaaaaaca cgagagcaca ttcgtttttg atacttgaaa gtcgtgatat tctcacgact
    16741 ttttattagc tttttggacc aatacgtgtt tttgactaga atcttctttt taatgatcaa
    16801 acgaagaagt agtaacagtg ttttttgcta ttgagaggat agttattttt tcaaaaatct
    16861 tttccaaaag gatttggttt tttcaggagt ttgtttgcta agttgatcgt tttttgtctg
    16921 ctttaagatg acttctaaac gtgtttcctt tagatttatt gcgtggtcgg tatgaaggat
    16981 aaacgcaaaa ggtgaagtca tatgcgtttc tgtaataata gtaacaggta aatggttttc
    17041 ttttgctaat ttcatataga gtatttgaag ttgaggtgcc agcttgaaag agatttttaa
    17101 gtgtaaaggt tgatagacta actgaaggct cggtaattct cttttcaaat agtcttttac
    17161 tgttttagtt tgagcttcgt ctaataaagc acttaaaacg actcgttcag catacgttcc
    17221 tagatagtag cgttgctgct caggatttaa tcttctttct ccccaggctc cttttaatag
    17281 cttatcttct aaattagtca tagataccct cgcttcttta taataataat agtttcttta
    17341 ttatatcgat ttctacaata aaataccaat ttgaaaattt tcggtaaatg tgttaaaaaa
    17401 caagaaagaa agtgattttt cttgcaaaaa acaaaggaag cttttcatga gattgctttt
    17461 taagttgatt aaaggcctag tttgtggtat tatgaacatg taaaatatta aaactcataa
    17521 ggagagtatt acaatgtcaa ttattactga tgtatacgct cgcgaagtcc ttgactcacg
    17581 cggtaaccca acacttgaag tagaagttta tacagaatca ggtgcattcg gacgtggtat
    17641 ggttccttca ggagcttcaa ctggtgaaca tgaagccgtt gaacttcgtg atggtgacaa
    17701 atctcgttac cttggtctag gtactcaaaa agcagttgat aacgttaata acattatcgc
    17761 tgaggcaatc atcggttacg atgttcgcga tcaacaagct atcgaccgtg caatgatcgc
    17821 tcttgacggt actcctaaca aaggtaaact tggtgctaat gctattcttg gtgtttctat
    17881 cgctgttgct cgtgcagctg ctgactatct tgaagtgcca ctttacactt accttggcgg
    17941 attcaacact aaagttcttc caactcctat gatgaacatc atcaacggtg gatcacactc
    18001 agatgcccca attgcattcc aagagttcat gatcatgcca gttggtgcac ctactttcaa
    18061 agaaggtctt cgttggggtg ctgaagtttt ccacgctctt aagaaaattc ttaaagaacg
    18121 cggacttgtt acagctgtag gtgacgaagg tggatttgct cctaaatttg aaggaactga
    18181 agacggtgta gaaactatcc ttaaagctat tgaagcagct ggttacgaag ctggtgaaaa
    18241 cggcattatg atcggttttg actgtgcatc atcagaattc tacgacaaag aacgtaaagt
    18301 ttacgactac actaaatttg aaggtgaagg cgctgctgtt cgtacatctg cagaacaagt
    18361 tgattacctt gaagagttgg ttaacaaata cccaattatt actatcgaag atggtatgga
    18421 tgaaaacgac tgggatggtt ggaaagttct tactgaacgc ctaggcaaac gtgttcaatt
    18481 ggttggtgac gacttcttcg ttacaaacac tgaatacctt gctcgtggta tcaaagaaaa
    18541 tgcagctaac tcaatcctta tcaaagttaa ccaaatcggt actttgactg aaacgtttga
    18601 agctatcgaa atggctaaag aagctggata tactgccgtt gtatcacacc gttcaggtga
    18661 aactgaagat tcaacaatcg ctgacatcgc agttgcaaca aacgctggcc aaatcaaaac
    18721 aggttcattg tcacgtacag accgtattgc taaatacaac caattacttc gtatcgaaga
    18781 tcaacttggt gaagttgctc aatacaaagg tatcaaatca ttctataact taaaaaaata
    18841 gactgtaaga cagaaatcgg tcattcgtag aatgcgattt cgtcgtcgca cccccgtcag
    18901 gctgactagg ttggtcacga caaaaggagt ggacatccag tcagctacga cgcaaaagtt
    18961 aaagaataga aagcttggga aaatcccaag ctttttgctt tctaaatagt aaaaatttac
    19021 tgtgggctaa tttatcctga gctaatgtat tagcgaggta aagttattga ggaaggcttg
    19081 gatttgtact gcccccaaac agttggacac tatattttaa atacagaact aagtcctttt
    19141 ataccaattg tcaagcacat caaggtttta actgaaaaaa tgttttagac aatagcctag
    19201 gtttagctgt tgtcttactt gttgtgctct gattagcata aaaaagtgta caagaaaaaa
    19261 accttgccta gtatttttaa gatcaaggtg ttacaatgat agagcaacaa cgactttaat
    19321 gattttgggt cgaagcgtaa ttgtaaagtt tgttatgcgt tatgaggtaa agcattgtcc
    19381 tgacaaggca atgtctagag gcaatcgtat gtggcttggt tgaagctgtt tgcgattgcc
    19441 tttttcgttt ctcatagaag tctgcgatat gacaaggatt ggtatgacta gcaaaagcaa
    19501 tgtcatggat acacttgaaa agaatctttg gagcataagg attcccatgt ttggtaatgt
    19561 gctcttgagc tagatagttg ccagactcat aatgtctaaa gtcaatccca atgaaagcat
    19621 taatttgatt agcagattga aaacgacgaa tagcaccgag ttcgccaata atacttgttg
    19681 cagttgtttc tacgatactt ggaatagagc gtagaatctt gtcttctggt aaaggttgag
    19741 ccgacgccac catcttatca aaaatagctt gacgacgttc agaaagtcta agtaattctt
    19801 tggcatagta gcgaacctct tctatcatcg gagaggtttt cgtaacagta aaataagact
    19861 gcttggctaa tgagacaagt ttttccacta agtagatccc acgcttgtca gagatacgtt
    19921 tagaggtaga ttgacggatg ctagctgaca atgctttgtc agctagctct agtacaaagc
    19981 tattacatgg aaaagccgtt accacattcc agtattactc accagttggt gcaaataaga
    20041 tgtgttccag ttcaggaaaa gtgacttgta agatcttgtg aaggcgattc ttaactctcg
    20101 aacaatatta tcctcagtca agttttgata gaagcgactc aagtcacgta gcagctgata
    20161 aacttcttcc tgaacgtaag ttggttttct aactagaata aattgagact gagccaattt
    20221 ttcagtgtct aacttatccg ctttacgcac ccgtagacta tctagttttc taaaggattg
    20281 agttgtgtat aagcgtagcc atttttctca aggaaggact gaagccgacg agaatagact
    20341 cctgttgtga tggtttccct tttgcctttt aaacaatagt atagccgttt ttcaaaatgt
    20401 tattaatgat tttttccttt attctagaag aataagtctg atactgtttc ttcttaataa
    20461 tctcaatgcc ctaacaatcc atcagtcgaa cggtatttat caaattactg cagttgactc
    20521 ttgcgttcag ttccctcacc ttgtggatgc cgtttagaac aatattagct tgctgagcct
    20581 tttggtaatg tgaacaaagc atctttatca ctcaaggaga agacaggttc ttgtggtaag
    20641 tgtccaacaa ggtcacgata aactcatcgt accgtttttg gcggaagtct agaaatgcct
    20701 tatgaatgta agcctcagaa acgtctctaa aactaaacaa gaaatacaag aacaaatgcc
    20761 cttgattctg gtacaaatgc tgtatcaggt tcaggtattg cctatctgcg ataatgacac
    20821 tctgcttttc cttaacaata tctttgaaag gaatgatttc gacattgaca ggcataaccg
    20881 ttgcaatagc tggcgggaag taaatcgaga gtgcattggt catcaaatcc agcgcagcag
    20941 tgttattggt caaaagatag acaggtatcg gtggcaaata tgtttttagg agttcctcta
    21001 actgtatcgt gaagagcagt aaatgatagg acggcagttt ccccacgata ccttctgcgc
    21061 tcatccattc ctcaacgatg gtttttagag tattgtagaa gctcttgttt cgtttttgct
    21121 gtcttctgag gtaatggaac aagtgtatat caggtaacaa aacttgaaga ttactgataa
    21181 agagacgtga gaaggaaacc aaaatccgtt tgaaaggaag ggagtttagg atattattgc
    21241 ctagtagtgg acgcagggat gctttcaagg tttttccaat tgtttttgtc atcaccaact
    21301 caaacaattc tttcactttt ttaggtgtcc atttatcctt atggaaagga ttattggtgg
    21361 tgcaaaaaca taagaaaata taatccaaat cctcatcagt taaatcagga tggtaccatt
    21421 ttccgatgat ttcctgactg gtcattttga tatcgtgata gatagacagt tttttcaagt
    21481 gtttgaatgc atctgtctga gggatcccca agttatcatg tcgccgtttc catataaggg
    21541 atatcagaat ggcaaagtat gaaaattcat aaggggcttt actggcatca ttaagtgtga
    21601 tggcttgatt ggagtttata atcagcgaaa ccactttatt cattgatgtt ttatcaaaat
    21661 cataaatggt cataccaaac tgatagtgca acaaggcgat cagaaagcgg atacggtatt
    21721 ctggtccaac aacatggttt tgccgaacgt ttaaacctac ctttttcaag tatttccgac
    21781 aattggtcct gatacggtaa gcagtggctt gagaaatata ctctcgttta atgaagtcgt
    21841 gtaggcttag ctctcctggt tcaattaaaa aacataacat ctttaagaat atcgaggttt
    21901 gatagagttt cttaaaataa ggcattttaa gttggtaggt cttatagggg atagaaacaa
    21961 tgtcgtcaca aatggttaag gtgagggtgt cttctaaatc cttaatcatt tcaatgagta
    22021 agttgtagac acgttgtttt ttgagttcgg tttcctgaca caactggtct atggagactt
    22081 cggaaacgtc taacaaaatg ttgagcagtg ataatttatc ttgtaatttg gtttctagat
    22141 gaaggtgtaa cataactgaa ctcctttcat ttttatagca gaaactcgta tttatttaat
    22201 tatcacataa ttaaataaaa cagtcaaata attcaatggt gacgtgtgtt taaggagtat
    22261 tgagaatgtc agatataagc aaaatgcagc tgaatattct taattttagg tatgaaaaag
    22321 cgtcgggatt gataaaaaat ctattgaatt gggtaaattt aagttgatat aataagttga
    22381 ttagaaaaat taataattca tttaaattct aatcagatgt aacgttccgg ggcgtgttaa
    22441 actgtctgaa catagaaaat acaggtttct aaggtgacta aagtaagtta aggaggattc
    22501 cttaaattct gtgataggaa cgtaaactct ctacaagagt agagcacgtc atcagtcagt
    22561 ctgggtgtct actggctgac aacgtcaaat aagataggca tgaaaaaata agggggaata
    22621 cagaatgttt ttaaaacacc aagatgtgaa acaaaaaaat tggagaatgc gtaaggtcaa
    22681 aaaactcttt gttagttcat gtatgctttt aacagtgggc ctcggagttg ccgtacctac
    22741 tgcattcagc caatctaatg gcgtgatggt cgtaaaggct gcggaagtgc cggcgacaga
    22801 tttatcacgt caggcgtctg attcggagag ggtagatgaa tcatctttat tgcagaaaga
    22861 aaacttatca gtagattcat ttaaattaga aaatttaaat ggatgggaag ctgaaaatga
    22921 tacagcaggt aatttgggga aatttaaaga tccagatagt tcgggctatc aaaatatttt
    22981 gacatcatct ggaaagaata tcagtgtagc tgttgctccc aaaggttcag gtaaaatgaa
    23041 cattaaagta actaaaagat caaattttca gggtggatat tatgtaggtg gtcttagaac
    23101 tcaaactccg gtattgaagt taaatgatgt ttatcgatat tcttttacaa ctaaaaaatt
    23161 atcaggaaat tcttcagagt tcaaaacgag agttaagccc gttgaatcta ataataaact
    23221 agggaaagag cttgttatta gggtggataa taaaaatgta tctactaagc atgattggct
    23281 tccagacatc tctgatggaa ctcatactgt ggacttcact ggtcttgata aaaaattatc
    23341 tgttgctttc agattttctc caagacaaac ttcgaatgtt gtttacgaat tttctaacat
    23401 aaatataaaa aacattagtc ctgcatcagt gccggctatt ccttcgaaag ttttagaggg
    23461 aaccagcgtc ttgtcgggta ctgcaatatc ttctggagat acattagaaa aaagaaaatc
    23521 gtttgatggc gatatcctaa gagtttataa agatagcaaa atcattgcta gaacagtaat
    23581 aaaaggcaat aagtgggatg ttaaactttc aaagcctctt attgcaggtg aaaaattaga
    23641 ttttgagatt ttgcatccga gatctcaaaa cgttagtaaa aaaatttcaa aacaagtcga
    23701 agctaaacca tttgatccag cttcctataa agaaaaagtt atagccaaat taaagccggt
    23761 ttatgaagct actagtgaaa aaatcacaaa tgatgcttgg ttggatgaaa atgcgaagga
    23821 tttgcaaaaa caaaaattag aagaacaata tatttctgga aaagtagcga tatcagaggc
    23881 tggaactaaa caagaagcta tagatgcagc atataataaa tattcaagtc aaacagatcc
    23941 agactctctt cctagtcagt ataaacaagg taataaagaa aatgaacaag aaaaagggcg
    24001 tcaagattta atccagactc gtgatctgac gttgaaagcc attcaagaag acaaatggct
    24061 aacagagcag gagaaaacaa ctcaaaaaga agaagcatta aaagcttttg aaactggtat
    24121 agaaagtgtt aatcaaacag tatcattaga acagttgaag caacggttaa tagtgtataa
    24181 agcttctgaa aaagattcag agaaaaaaga atatcctgag tcaattccta atcagcatat
    24241 tccagggaaa gaaaaagaag ttaaagctgc taaacaagaa gaacttaaaa aattacatga
    24301 cacaactctt gaaaaaatca atcaagataa atggttgacg ccagaccaac aagctgaaca
    24361 gttaaaacaa gcggaagtta cttttaaaaa aggccaagaa gcaattaaaa gtgctcagac
    24421 tttaactcag cttgagacag acttagctga ttatgtttct gagaatgaag gtaagggaaa
    24481 ttctattccc gataaataca aatctggcaa taaagatgat ttggtaaata aggctgaagt
    24541 taaacttaag gaagctcacg aagctactaa acaagcgatt gaaaaagatc catggttgag
    24601 tccggaacag aaaaaagctc aaaaagaaaa cgctaaagca agattagatg caggtttgaa
    24661 agctgtcgaa actacagaaa gcttagataa acttaaagaa gttgagagtg acttccttga
    24721 taaagaaaaa gcaaaatcta ttccatctca acatcaagca ggaactcctg aagttgctcg
    24781 caaaactttc ttagataact ttgaaaaaga agctcaaaaa gaacttgaat caattaaaaa
    24841 tgacgttaca ttaacagatg ctgaaaaagc aacagctaaa gctaaagtag aagcacaact
    24901 tcaagaagct aaagataagg ctaaggaatc aaaatcgttt gatgatttga agaacattca
    24961 agataagttc aattctgaat taccacacac aacaggtaag ccgcttaaag atcaacaatc
    25021 tgatgctatt gcagaattag agaagaagca gcaagaaatt gaaaaagcta tctcagaaga
    25081 taagacattg tcaaaagatg aaaaagagaa acaaattgct gattctaaag cgaaattagt
    25141 cgctgagaag gaaaaagttt ctaaagcacc tgatgctgat gctgttaaga aagctcttga
    25201 gtcaggtaag caagaaattg ctaaggctta tgttccacaa aacttagaag atcacaagaa
    25261 aaaacttctt gcagagttga agcaaaaagc aaatgatact gaaaaagcga ttgatttcga
    25321 taaaactttg acagcgaaag aaaaagaaga gcaaaaagcg aaaacaaaag aagaacttca
    25381 aaaagcaaca gaagctgttg gagcaattga caatcgtgaa gaactagata aaaaagtccc
    25441 agaacttaag aaagctattc aagattctca cgttaaagga gaccttgaag gtgttaagaa
    25501 taaagctatt gaagatcttc aaaaagttca tgacgaaaca gttgctaaaa taaatggtga
    25561 tgataccctt gacaaagcta ctaaagaagc tcaagtgaaa gaagctgaca aagctttggc
    25621 agcaggtaaa gatgctatca ctaaagcaga tgatgctgat aaagtgggtg cagctgttac
    25681 agagcacaca ccaaaaatta aagcagcaca taaaactggt gatcttaaaa aagttcaaga
    25741 agaggctaac caagctcttg acaaagcagc tgaaaaagaa cgtgaagaaa tcaataatga
    25801 tgctacacta acgacagaag ataaagcaaa acaactgaaa gaagttgaga cagctcttac
    25861 taaagctaaa gataacgtga aagctgctaa gacagcagac gctatcaatg acgcacgtga
    25921 taaaggcgta gcaacaattg atgccgttca taaagcaggt caagacttag gtgctcgtaa
    25981 gtcaggtcaa gtcgctaaac ttgaagaagc agctaaagca acgaaagaca agatttcagc
    26041 tgatccaact ttgacaagca aagaaaaaga agagcaatct aaagctgtta acgctgaact
    26101 taagaaagcg atagaagctg ttaacgcagc tgacacagct gacaaggttg acgatgctct
    26161 tggtaaaggt gtcatagaca tcaagaacca acataagaca ggtgaccctg tcgtagctcg
    26221 tcgtgaggct catggtaagc aacttgatag agtcgctcaa gaaactaaag atgcgattga
    26281 aaaagaccct actttgacga ctgaagaaaa agctaaacaa gttaaagacg tagatgccgc
    26341 taaagaaaga ggcatggcta agcttaatga agctaaagat gctgatgctt tagacaaagc
    26401 ttacggtgaa ggtgttacag acatcaagaa ccaacacaag tcaggtgacc ctatcgaagc
    26461 tcgtcgtgga ttacacaaca agtcaatcga cgaagtggc
//
LOCUS       DATTYN010000024        25494 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.24, whole genome shotgun sequence.
ACCESSION   DATTYN010000024 DATTYN010000000
VERSION     DATTYN010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25494
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.24"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            31..357
                     /locus_tag="VB649_001279"
     CDS             31..357
                     /locus_tag="VB649_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEP1670227.1"
                     /translation="MYFPVSATLIEFLILAIVEKNDSYGYDISQTIKLVANIKESTLY
                     PILKKLEKAGFLTTYSQEHQGRKRKYYAVTSSGRAQLIFLKKEWQSYKFALDGIIEGS
                     LRHDKD"
     gene            344..931
                     /locus_tag="VB649_001280"
     CDS             344..931
                     /locus_tag="VB649_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEP1670228.1"
                     /translation="MTRTEYLAELDKYLRKLPREDYHEAMEYYIEYFDEAGPDRESQV
                     IDDLGNPKEAASEIISNVLGKHLATPEKTPKNRATIIGLTILSLFAAPIALPVLLALI
                     LFIIACLMLGLTAIFAAYIFGLAGILVAGVTLFESLTLIGSSIPAQAMGIGSALLCFG
                     GGLLIWIIATAILRFSGRAFVAFIKWISNKKGAQA"
     gene            928..2007
                     /locus_tag="VB649_001281"
     CDS             928..2007
                     /locus_tag="VB649_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEP1670229.1"
                     /translation="MKNISRKCFMTSVVCIILGGILLGAGYATGGLQDIKHQTAPKKV
                     IKTFDQITALDIDSSASTITVETGPVQRPTVTYYTHPKFIDPIVTTVTSKTLSLSQKP
                     KDVVITGGIEILGFTLNNSRQEKNYRSITITVPEKTSLNEVKGSNVPHTTLSNLTVQD
                     MQFDGNLTLLHTKVKKATITGMLEATKSQLTNLELKADYSFSNLTDSSVENGTISLGN
                     GQLTTKDTTLKAVNIQSLHPGGIEAERTTLENVTFTVSKSKEEEENDYYDNDAIFTAH
                     ALTLKGTNTISGGDIDVDITLTKAKAIAYRARTENGKVSLGSQLTPAKIGKESTSDVI
                     SYVAENKAATGNLTVNLNKGDITIK"
     gene            complement(2122..4395)
                     /locus_tag="VB649_001282"
     CDS             complement(2122..4395)
                     /locus_tag="VB649_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEP1670230.1"
                     /translation="MLEELKTLIKNPKLMITMIGVALVPALYNLSFLGSMWDPYGRVN
                     DLPIAVVNHDKPAKRADKSLTIGNDMVDKMSKSKDLEYHFVSAKQAQEGLKEGDYYMV
                     ITLPEDLSQRAATLLNPEPQKLTIRYQTSKGHGMVAAKMGETAMAKLKESVSQNITKT
                     YTSAVFSSMTDLQSGLKEASAGSQALASGAKTAQAGSQTLSTNLVALTGASQQFQQGT
                     GRLTSGLTTYTDGVNQVKNGLGTLSTDIPNYLNGVSRLSQGASQLNQGLSQLTQATTL
                     SDEKAKGIQSLIVGLPVLNQGIQQLNTELSTLQPPNLNADELGNSLGAIAQAAKQVIA
                     EETAAQNEELSALQATSVYQSLTAEQQGELAAALSQSDKSQTVSAAQTILSSVQTLST
                     SLQSLSQEDQSKQLEQLKEAVAQIANQSNQALPGASSALTELSTGLAKVNGSLNQQVL
                     PGSNQLTTGLAQLNRYNTAIGSGVIKLSEGTNALSSKSGELLDGSHQLSEGATKLADG
                     SSQLSQGGYQLTSGLTELSTGLSTLNGSLAKASQQLSLVSVTDKNAKAVAKPLVLNEK
                     DKDGVKTNGIGMAPYMIAVSLMVVALSTNVIFANSLSGRPVKDKWDWAKQKFVINGFI
                     STMGPIVLYLAIQSLGFEARYGMETLGFIMLSGWTFMALVTALVGWDDRYGSFASLVM
                     LLLQVGSSGGSYPIELSGAFFQKLHPFLPMTYVVSGLRQTISLSGHIGVEVKVLTGFL
                     LAFMVLALLIYRPKKTV"
     gene            4530..5063
                     /locus_tag="VB649_001283"
     CDS             4530..5063
                     /locus_tag="VB649_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP1670231.1"
                     /translation="MVNRKENTKQAILKAMVMLLKTESFDDITTVKLSKRAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKKYQNKEQAFLEVFEFLQREQLLSSLLSANG
                     TKEIQAFIINKVRLLITTDLQDKFRTEELSQTEKEYQSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTQFVLKMLTST"
     gene            complement(6073..6504)
                     /locus_tag="VB649_001284"
     CDS             complement(6073..6504)
                     /locus_tag="VB649_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEP1670232.1"
                     /translation="MTIEELKQRLEGIRWIDKEISQLYLELQYLETGLFKQTTLTQAR
                     VQTSRVNSTENQLVAQLTLKEDITSRIDRLTQDRLELVSIIDKLEIPKYRLALNLYYV
                     QHKLDIEASEIMGISRTTFFRYLRQGQAELVSLLTHAEKEN"
     gene            complement(7003..7506)
                     /locus_tag="VB649_001285"
     CDS             complement(7003..7506)
                     /locus_tag="VB649_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670233.1"
                     /translation="MKVLYIETFTRAMKKKGITQGKGELDDYSLTIDLDNLFIVMGKE
                     SFELARIPGTKGGYRYFFLCPDCGRRCRKLYKRYLFYACGNCQQIHKQTLNRSKTDCQ
                     YYWERALREARKVQPGWTPERGGYVFDGFPSRPKRMKRDRYYKHYQRFLNYVRKGDSY
                     WLRGLSR"
     gene            complement(7600..8130)
                     /locus_tag="VB649_001286"
     CDS             complement(7600..8130)
                     /locus_tag="VB649_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670234.1"
                     /translation="MTLKTISDKPQTFTFTYDFEDIDTAKVASNAVFGYMFGTYHAPV
                     IEATIKGKGQLVLEYAEDKKLSKIFKRICDGFKDYYTHQGQENEIKEDYKLERVQQLK
                     QSEDFDSLLDKLVACELELMELADSVLDDDYPDTAVNGVHGNLKALDNQAMALLKNLD
                     AEGEYKALWKYASREA"
     gene            complement(8151..8324)
                     /locus_tag="VB649_001287"
     CDS             complement(8151..8324)
                     /locus_tag="VB649_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670235.1"
                     /translation="MKIKLFYQKHKQSLEEFENQVNDFMAGVEVVDVKYTEATSGDYE
                     AMTTTLGLLVLYK"
     gene            complement(8661..10163)
                     /locus_tag="VB649_001288"
     CDS             complement(8661..10163)
                     /locus_tag="VB649_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEP1670236.1"
                     /translation="MKNLESEILEARENEQPPRTMKELENRIFQAGEQWREEHTETKI
                     NESTGDVTEKVAMPQVFTVAKMLSEIITFTFISKSNVPDYSLLYIYDLDEGIYTASND
                     LFNRFCKTFDVRIKPRKWPQIKLMVRTLTRIKKPLESAYLIPVQNGIIDLRTKELLPF
                     SPKYVITSKISTAYHAPKRIPTDREGKTFDDWLNSIACNDSELVILFWQIILEAINPN
                     HTRNKFAIFYGDGNNGKGTFQRFLINLIGESNVSALKPVQFAEKHNLETLVGKVCNIG
                     DEAPNEYLKNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGW
                     YRRIMIVPFNADFNGEKEKPWIKNDFLANKEVLEYALYKAINQKSFTHFIEPQAVKGL
                     LEEYQEDNDYLLSWVKHEYMERGWHELDVVPVFIATRSLKHYAEDMGIPKPNVYGAGK
                     ETIRHLQQLTPNKYQLKKARVKVEDYDKLDPLEFERPKLGRVNHAITKKE"
     gene            complement(10183..11052)
                     /locus_tag="VB649_001289"
     CDS             complement(10183..11052)
                     /locus_tag="VB649_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEP1670237.1"
                     /translation="MAIYEARGFQSNLVYLFDKMEPFQYIERFKPLVVPEGADLEEYK
                     RTQAPYCLSGKITAEKTGSYKRNNISLVYRDLIFLDYDEIKGPAQGFIEAVSRALFGF
                     SYILYPTIKHTPESPRFRLVVKPGGVMNEETYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPADYQKIVEHGLDYPVPKSRQNRTSGQGVKPQTYTPRASGQRSITMRVID
                     TLFNGFGDEGGRNVALTRFVGLLFNKWVDCDIETAYELTKIANSVTANPLPERELDRT
                     FESIARAEFRKRG"
     gene            complement(11187..11468)
                     /locus_tag="VB649_001290"
     CDS             complement(11187..11468)
                     /locus_tag="VB649_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEP1670238.1"
                     /translation="MFSLSKESEQDLTQGVLELVESYLEAREQTPPRLLGLITAQQVK
                     DELGIKAKTLKRWEDNGLRRCQPPLEDTRKIFYRVSDVLIFLGVENGKI"
     gene            complement(11461..11793)
                     /locus_tag="VB649_001291"
     CDS             complement(11461..11793)
                     /locus_tag="VB649_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEP1670239.1"
                     /translation="MTELEERILRLIPVGADNPRAGRYIAELLGLDIRTLRENIHRLI
                     VRHGVPIVAKRGLVSGYYIPANDTERLEGIRELKAQYDTEGKRLDVLIKADLESYKKL
                     LKGADMNV"
     gene            complement(11805..12005)
                     /locus_tag="VB649_001292"
     CDS             complement(11805..12005)
                     /locus_tag="VB649_001292"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670240.1"
                     /translation="MNELDLTPGQYLAFILITLVLLAYELYRFYNDSEIIELPDKQEE
                     PASQQLNPNYGAYIWLAGRRYN"
     gene            complement(11998..12207)
                     /locus_tag="VB649_001293"
     CDS             complement(11998..12207)
                     /locus_tag="VB649_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670241.1"
                     /translation="MTDKTNDILVDYEGLCGELNDIMEVLELASTEDGPKTFPILHTA
                     NHALKKLITEHCDIASEYRKELNHE"
     gene            complement(12204..12632)
                     /locus_tag="VB649_001294"
     CDS             complement(12204..12632)
                     /locus_tag="VB649_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670242.1"
                     /translation="MKQYFEDFEAKLQVTEEKLDILSEWHIAKGHNGASGIAEECRTA
                     ISNLWIEFYRLSERYKKTEASHEQVVQSNLDNLLGEMKRYDDECTERYEKAPDWLLFN
                     FLDKAIKENNLSNGIIDSTVSTWTYLRSLIYKDLKERGLV"
     gene            complement(13007..13195)
                     /locus_tag="VB649_001295"
     CDS             complement(13007..13195)
                     /locus_tag="VB649_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670243.1"
                     /translation="MNGKKIAEIRKIQRLSQEELAEKAQVSRSIISFLETGKEKDVKL
                     FTLTRIAKALNCKVEDFL"
     gene            13385..14005
                     /locus_tag="VB649_001296"
     CDS             13385..14005
                     /locus_tag="VB649_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670244.1"
                     /translation="MKIGDIVKEYRKRNKLTMQEFADKIGKTKGYISMLEKGENPQTH
                     KPIAPTFETLREIAKAMGIELNTLIQKLDGDQVIKVNSTRYDWDDEEENLRNWGTYDW
                     DGNFSPSLFHEDIFIGIKNTLSNIDEVTFTRSDIESFYSSCIIDNVRITDRKSLIEYL
                     KKSIKGFNELVHGISDFDEQSLDSGLLSVLARDRNKYKFYLTQLEP"
     gene            14380..15384
                     /locus_tag="VB649_001297"
     CDS             14380..15384
                     /locus_tag="VB649_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEP1670245.1"
                     /translation="MTDLTTSQIERQNILNNSLAIKQAEEILKVPGFYFEDSFYFTNS
                     QIASFFDVDIRTIERLVEAHKIELTKNGYHTLRGEQLANFKENAFATDTNVGSKVTQL
                     SISSFRTLLNFAMLLTNSDIAKQVRNTLLDIVINVLTEKTGGHVKFINQRDKNYLSTA
                     LEEDNARKIFTNAIDKYVSGSNFKYGQLTNEIYKAIFKERASEYKKILKLNKNDNTRA
                     TMYSEVLIVIASFEKGVAYEIEQKSKSLNQKITNADVIEIIQKLASHPMQEPHLMHAR
                     EKMASRDLSFRNARHEKLAQYIRPISEEDFERFIGEQSKSLSEQIDEHRQVFERLRDK
                     "
     gene            15384..15836
                     /locus_tag="VB649_001298"
     CDS             15384..15836
                     /locus_tag="VB649_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEP1670246.1"
                     /translation="MGTINYFFAEEAILLHDIEVIEKIGGLHGVKDKGRVFSVFEHLQ
                     NDDYYPDFETKLTVLVFNTVQFHMFNDGNKRSSIVFGVKFLTINHFDYLIPFFIETME
                     NIVLWVAMGLIDFKFLKEIISSILYYEELTEQVKERLVQIALTIENYK"
     gene            15925..17097
                     /locus_tag="VB649_001299"
     CDS             15925..17097
                     /locus_tag="VB649_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP1670247.1"
                     /translation="MIMKITEVKKKNGATVYRASVYLGVDQVTGKKVKTKVTGRTQKE
                     VKQKAKQEKIAFQQDGFTRFQATSIASYQELAELWWESYKHTVKPNTQDNVKKLLDNH
                     VLPLFGVYKLDKLTTPLIQSIVNKLADKTNKGEPGAYLHYDKIHALNKRILQYGVTMQ
                     AIPANPARDVVLPRNTQKAKRKKVKHFENQDLKKFLDYLGGLDLSKYRNLYEATLYKF
                     LLATGCRINEALALSWSDIDLENATISITKTLNHLGQINSPKSKASYRDIDIDQATIT
                     MLKAYQLRQIQEAWKLGRTETVVFSDFIHDYPSNKTLGTRLKTRFKRAGVPNIGFHGF
                     RHTHASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            complement(17192..17803)
                     /gene="rpsD"
                     /locus_tag="VB649_001300"
     CDS             complement(17192..17803)
                     /gene="rpsD"
                     /locus_tag="VB649_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEP1670248.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(18533..18805)
                     /locus_tag="VB649_001301"
     CDS             complement(18533..18805)
                     /locus_tag="VB649_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEP1670249.1"
                     /translation="MSDAFTDVAKMKKIKEDIRAHEGQLVELTLENGRKREKNKIGRL
                     IEVYSSLFIIEYSDSSDTPGAIDNSYVESYTYSDILTEKTLIRYLD"
     gene            complement(18822..20183)
                     /gene="dnaB"
                     /locus_tag="VB649_001302"
     CDS             complement(18822..20183)
                     /gene="dnaB"
                     /locus_tag="VB649_001302"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEP1670250.1"
                     /translation="MPEVAELRVQPQDLLAEQSVLGSIFISPDKLIAVREFISPDDFY
                     KYAHKIIFRAMITLSDRNDAIDATTIRTILDDQDDLQSIGGLSYIVELVNSVPTSANA
                     EYYAKIVAEKAMLRDIIARLTDSVNLAYDEILKPEEVIAGVERALIELNEHSNRSGFR
                     KISDVLKVNYEALEARSKQTSNVTGLPTGFRDLDKITTGLHPDQLVILAARPAVGKTA
                     FVLNIAQNVGTKQKKTVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNV
                     TIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKPEN
                     RQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADI
                     VAFLYRDDYYRKEGDDAEEAVEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSSIAQF
                     EER"
     gene            complement(20219..20671)
                     /gene="rplI"
                     /locus_tag="VB649_001303"
     CDS             complement(20219..20671)
                     /gene="rplI"
                     /locus_tag="VB649_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEP1670251.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSI
                     GELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISE
                     ELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA"
     gene            complement(20668..22644)
                     /locus_tag="VB649_001304"
     CDS             complement(20668..22644)
                     /locus_tag="VB649_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEP1670252.1"
                     /translation="MKKFRFETIHLIMMGLILFGLLALCVSIMQSKILILLAIFLVLL
                     FVVALLWYQKEAYQLSDLAHIELLNEQTEDNLKTLLDNMPVGVVQFDQETNAVEWYNP
                     YAELIFTTEEGFIQNSLIQQIITEKRREDISQTFEVSGNKYTSYIDVSSGIFYFFDSF
                     VGNRQLADASMLRPVVGIISVDNYDDITDDLSDADTSKINSFVANFIDEFMESKRIFY
                     RRVNMDRYYFFTDFKTLNDLMDNKFSVLEEFRKEAQDAQRPLTLSIGISFGEENHSQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFAGNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISVSQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFQNVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSKGSDSVEIQNISATDFEEYKQINEIILQGERLGDSIIVAAGEKNHLY
                     SNVIASKAADTILSMAHVEASFVLVETASHKIAISARSRSKINVQRVMEKLGGGGHFN
                     LAACQLTDISLPQAKHLLLKTINMTMKETGEVES"
     gene            complement(22734..24632)
                     /gene="mnmG"
                     /locus_tag="VB649_001305"
     CDS             complement(22734..24632)
                     /gene="mnmG"
                     /locus_tag="VB649_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEP1670253.1"
                     /translation="MTHEFTESYDVIVIGAGHAGVEASLATSRMGCRTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTE
                     IQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGL
                     EKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTD
                     AMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMK
                     RMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEG
                     NGKAHRKY"
     gene            complement(24756..25073)
                     /locus_tag="VB649_001306"
     CDS             complement(24756..25073)
                     /locus_tag="VB649_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEP1670254.1"
                     /translation="MIVRNGKNFLTRDAADQYYTIGGTSLVGEKTHETVLRETLEEVG
                     IRTKVNQLAFVVENHFDIDDVFWHNIEFHYLVSPLEDPKLEMIENASDRFVNGFQSIN
                     WIK"
BASE COUNT         7659 a         5263 c         4441 g         8131 t
ORIGIN      
        1 taaaattttt atatatggaa ggagcctaaa atgtattttc cagtatcggc taccttgatt
       61 gaatttctga ttttagccat tgtcgaaaaa aatgattctt acggttacga tattagtcaa
      121 accattaaac tagtggctaa tatcaaagaa tccaccctct atcctattct taaaaaattg
      181 gagaaggcag gttttttgac aacttatagt caagaacatc agggacgaaa gcgtaaatat
      241 tatgctgtca cttcttcggg gagagcacag ctgatttttc taaaaaaaga atggcagagc
      301 tataaatttg ccttagacgg gattattgaa gggagcttaa gacatgacaa ggactgagta
      361 tctagcagaa ttagataaat acttgcgcaa actacctaga gaagactacc atgaagcgat
      421 ggaatattat attgaatatt ttgatgaagc tggtcctgac agagaaagcc aggttatcga
      481 cgatttagga aatcctaagg aagctgccag tgaaatcatt tcaaatgttc taggaaaaca
      541 cttggcaact cccgagaaaa ctcccaaaaa tcgggcaaca attattggat taaccatttt
      601 gtccctcttt gctgctccga ttgctttacc cgtattgctg gcgttgattc tctttattat
      661 tgcctgccta atgctcgggc tcacagctat ctttgccgcc tacatttttg ggcttgcagg
      721 tattcttgtc gcaggagtga ctctgtttga aagcttgacc ttgattggct catctattcc
      781 tgcacaagct atgggcatcg gcagcgcctt gttgtgtttt ggtggtggtc ttcttatttg
      841 gattattgcc acagcaatcc ttcgtttttc aggacgggct tttgttgcct ttattaagtg
      901 gatcagtaat aagaaaggag ctcaagcatg aaaaatatct cacgcaaatg ctttatgacc
      961 agtgtggtat gtattattct aggaggcatt cttctagggg ctggctatgc aactggagga
     1021 cttcaggaca ttaaacacca aacagctccc aaaaaggtca tcaaaacatt tgaccaaata
     1081 actgctcttg atattgacag ttctgcctca actattacag tagagacagg acccgttcaa
     1141 agaccaacag tgacctatta cacacatcct aaatttattg accctatcgt cacaacagta
     1201 acaagtaaga ccctatctct ttcgcaaaaa cctaaagacg ttgtcatcac tggtggaatt
     1261 gaaattttag gttttactct caataatagt cgtcaagaga agaactaccg ttctattacc
     1321 attactgttc ctgaaaaaac tagcctcaat gaagttaagg gaagtaatgt cccacatacc
     1381 actttgtcaa atctaactgt ccaagatatg caattcgatg gcaatcttac tcttttacat
     1441 accaaagtca agaaagctac tatcactggt atgttggaag ccactaaaag tcagttaaca
     1501 aatctcgagt taaaagctga ttattctttt tcaaacctga ctgattctag tgtggaaaat
     1561 gggaccatca gcttaggaaa tggacaacta actactaaag ataccactct aaaagccgtc
     1621 aatattcaat cattacaccc tggtggtata gaagccgaga gaacaaccct tgaaaatgtg
     1681 accttcactg tttctaaaag caaagaagaa gaggagaacg actactatga caatgatgct
     1741 atcttcaccg ctcatgccct tacccttaaa gggactaata ctattagtgg cggtgatatt
     1801 gatgttgaca taaccttgac aaaagcaaag gccatcgcct acagagcaag aaccgaaaat
     1861 ggtaaagtct ctcttggctc acagctgaca ccagctaaga ttggtaagga atcaacttca
     1921 gatgttattt cttatgtggc tgagaataaa gcagctactg gaaatttaac ggttaatctc
     1981 aataagggag acattactat caaatgatct taacaagaca ataaaaactt gacagaaatt
     2041 gtcaagttat tgtcaaaata agacaaaaaa accgcatcta gtataactgc cttagatgct
     2101 gtttttttga ggttatttta tttagactgt tttcttggga cgataaatga gtagtgctaa
     2161 taccataaat gccagtaaga aaccagttaa gactttcact tctactccaa tatgacctga
     2221 taatgaaatg gtttgtcgta aaccagatac cacataagtc attggtaaga aaggatgtaa
     2281 cttttggaag aatgctccac ttaactcaat ggggtaagag ccacctgaag agccaacctg
     2341 aagcaataac atgaccaaag aagcaaaaga gccatatcga tcatcccaac cgaccaaagc
     2401 tgtgacaaga gccataaacg tccaaccact taacataata aatcctaagg tctccatacc
     2461 ataacgggct tcaaacccta atgattgaat agctaagtag agaacaatgg gtcccatagt
     2521 cgaaataaaa ccattaataa caaatttttg tttagcccaa tcccatttat ctttgaccgg
     2581 acgaccagat aaagaattag caaaaatgac gttggttgaa agggccacaa ccattagaga
     2641 aacagcaatc atataaggtg ccatcccgat cccattcgtc ttaacaccat ctttgtcttt
     2701 ctcatttaac acaagaggtt ttgcgacagc tttagcattt ttatcagtca cagaaacaag
     2761 cgataactgc tgagaggctt tggctaagga accatttaag gttgacaatc ctgttgataa
     2821 ttcagtcaat ccgctcgtta attgataacc accctgactc aattgagaac taccatcagc
     2881 tagtttagta gcaccctctg ataattgatg gctaccatct agtaactctc cggacttgga
     2941 tgacaaggca ttggtacctt ctgagagttt tattacccca gaaccaatgg cagtattata
     3001 cctgtttaat tgtgctaatc ctgttgtcaa ttgattactt cctggtagaa cttgttgatt
     3061 taagctacca tttacctttg ctaatcccgt tgataattca gttaaagcag aacttgctcc
     3121 cggcaaagct tgattggatt gattagcaat ctgtgcaaca gcttccttaa gttgctccaa
     3181 ctgttttgac tgatcttctt gagagagaga ctgtaaactt gttgacaaag tttgaacaga
     3241 acttaaaata gtttgggctg cagatacggt ctgactttta tcagattgac tgagggccgc
     3301 agctaactct ccttgttgtt cagcagttaa tgattggtaa acgctagtag cttggagagc
     3361 cgataattct tcattctgag cggcagtctc ttcagcaatg acttgtttgg cagcttgagc
     3421 gatagctcct aagctattac ctaactcatc agcattaagg ttagggggtt gcaatgttga
     3481 tagctctgta tttagttgct gaatcccttg atttaggact ggtagtccta caattaagga
     3541 ttgaattccc ttagctttct cgtcagaaag tgttgttgct tgtgtcaact gtgaaagacc
     3601 ctgattaagc tgagaagctc cctgggataa cctagaaacc ccgttcaaat aattggggat
     3661 gtccgttgat aatgttccta acccattctt gacttggttg acaccatctg tataggtagt
     3721 caaacctgat gtcaatcgac cagtaccttg ttgaaactgt tggctagcac ccgttaaggc
     3781 tactaagttc gtcgaaagtg tttgactccc cgcctgagcg gtcttcgctc ctgaagcaag
     3841 tgcttgactt ccagctgagg cttcttttaa tcctgattgg aggtctgtca tactgctaaa
     3901 aactgctgag gtataagtct tcgtaatgtt ttgcgaaaca gactctttca acttagccat
     3961 cgctgtttcc cccatcttag cagcgaccat tccatgtcct ttactcgttt ggtaacggat
     4021 agttaatttt tggggttcgg gatttaataa ggttgctgcc cgttgagaaa gatcttcggg
     4081 taaagtaata accatataat aatcaccttc tttaagtccc tcttgagctt gcttagctga
     4141 gacaaaatga tactctaaat ctttactttt agacatcttg tccaccatat cattcccaat
     4201 tgtcaatgac ttatcagctc tctttgcagg cttatcatga ttaacaacag caatgggaag
     4261 gtcattgacc cgaccataag gatcccacat tgagcctaga aaggataaat tatataaggc
     4321 aggcactagg gccacaccaa tcattgtaat cattaatttt ggatttttaa taagtgtttt
     4381 caattcttct aacatatttt ctcctaaaat ggacatggtg ttcaaaaatt atgataaaat
     4441 atattataca atttaaattt aaatttacaa gataaaaaat ttcacttttg gacattatgt
     4501 ctaaaagtgt tcaaaaggag agatggtaga tggtcaaccg taaagaaaat acgaagcaag
     4561 caattttaaa agcaatggtt atgttactaa aaaccgaaag ttttgacgat attaccacag
     4621 ttaaattatc taaaagagct ggaattagtc gctctagttt ttacacacac tataaagata
     4681 aatatgaaat gattgactat tatcagcaaa ccttttttca caaattagaa tatatttttg
     4741 agaaaaaata tcaaaataaa gaacaagcct tccttgaagt atttgaattt ctccaaagag
     4801 aacagcttct ctcttccctt ttgtctgcta acggtactaa agaaatacag gcctttatca
     4861 tcaataaagt tcgcctactc atcactactg atttacagga caagttccgt accgaagagt
     4921 tatctcaaac ggaaaaagaa taccaaagta tctacttagc ccatgctttt tttggtgtct
     4981 gtcaaagttg gattgctaaa ggtaaaaaag aatcacctca agaaatgaca caattcgttc
     5041 tcaaaatgct tacgagtacc taaataataa cccttacgaa agtatcattt tacaagtcat
     5101 cagccttagt gataactttt ttagaagcca tagtaaaatg aagggatcag gataaatttg
     5161 ttatgagata caaaaaaaag cctattaaat aggctttttg taagtttaat cttaaaatta
     5221 aagcattttg ttatacagtt aagattactt agctttacac gttctttaca ctccctaacc
     5281 cctgatatga taggcttcta actaaataac ttataattag acagtgttaa atactccccc
     5341 aaagttcgca aaaaggggag caaaaaaagg gcctttcagt agccctaagt tatgagttca
     5401 gcaggcaaga aactagcacc gctccaaggt gtttttttag ttccctggta tcttgctgat
     5461 actattgtat caaaaagcac gcgcttatct tccaatattg gcgaattttc caagatagcg
     5521 cgtgatcatg tattttcaga ctcgcataac cttcccaaaa cctttacatt atcaaaactt
     5581 ttaaaaaggg aaaattgtgc tcgaaaaagg tcggggttgt agccccctgg ccaaacctac
     5641 ccccgttcta aaaatgaggg gactaatcac aacctttact gtatcctact gtgttttact
     5701 gtatccacta gtattgtgtt actaatccta tgattttaca aaatcgtttg ctattcgctt
     5761 tatatgctct ttgaaactag ccaaaacgta acgctttttg ttaggattaa ccctattttg
     5821 ttaggattat gttaccattt gggaaaccta aaatactcta caaactcaat aataccaatg
     5881 gtttaagtta tttttacccc ctttagaatt tttggcgtga gaaaaaatgt acaatgacgg
     5941 cgtgaaggtc ggacgtgtac ccatggtagg ttagtccccc cgcattcaaa aaggcctcta
     6001 gctccgtttc taaaggccta attattccct ggtttattta tcggataagc tcaaacacgc
     6061 gctaaaacat agctaatttt ctttctctgc atgagttaac aagctaacta attcggcttg
     6121 tccttgtctc aaatatctaa aaaatgtcgt cctacttatt cccattatct cactagcttc
     6181 aatatctaac ttatgttgaa catagtaaag gtttaaggct aagcgatatt tcgggatctc
     6241 tagcttgtca attatgctga caagctccag gcggtcctgg gttagtctgt caattctact
     6301 tgttatatct tccttaagtg ttagctgggc aactaactga ttttctgtac tgtttaccct
     6361 gctagtctgt accctggcct gcgttagtgt tgtctgcttg aatagtccag tttccaagta
     6421 ttgaagttcc aggtaaagct gactgatttc tttatcaatc cacctaatac cctctagcct
     6481 ctgctttaac tcctctatgg tcattgttgc ccctcctatg gtaaaataag cttgttgaaa
     6541 cttcttaccc tgcgtgtgtc tcgcggggct ttttcatgcc taaaattctg taactgcctg
     6601 cgcgtgttct tttgttcgtc catggttcaa tgggctgttt tctctttgtt cgctctctgt
     6661 tcaatcacgc gccaccatgt ctaaacatta tctcttttag actgccaaaa ataccgaata
     6721 cctccccgga atctccctat ttttacttat ccaacctagc ctaaacctaa tcattttcat
     6781 tcatttaact ttaaggatta tatagcgttc agatattcgt cgttttgaaa aatcaaaaaa
     6841 cgttccgtat ttttgcaccc tttcaacact tagtgattgc aggtttttac cctgtgaatg
     6901 cttgatagta ctagcttttt agctcccaac cgttccgtca ttatttgttt tgtaaagcga
     6961 acatttgtag tatttgttcg ttttggaaat tgccaaagta cttcacctag ataaccctct
     7021 cagccaatag ctatcccctt ttctaacata gttcaaaaac ctttgataat gtttataata
     7081 tctatcacgc ttcattctct ttggacggct aggaaaacca tcaaacacat atccgccacg
     7141 ttcaggggtc caccctggtt ggaccttcct agcctccctt agtgcacgtt cccaataata
     7201 ctgacaatct gtcttactgc ggtttagcgt ctgtttatgg atctgctgac agtttccgca
     7261 agcataaaac agataccgct tatatagttt cctgcaacgc ctaccacaat cagggcaaag
     7321 aaagaaatac ctataaccgc cttttgttcc tggtattctg gccaattcaa agctctcttt
     7381 acccataaca ataaaaaggt tatctaagtc aatggtcaag gaataatcat ctaattcacc
     7441 cttaccctgg gttatccctt tctttttcat agctctggta aatgtctcta tatacaatac
     7501 tttcattcaa aaaatacccc tatactgtaa aaacccaaaa ctattggctt aagtcctaga
     7561 aacagcaaaa agaggcgggg cctctcttca ctattctagc tatgcctcac ggctagcata
     7621 tttccacaat gctttatatt cgccctcggc gtccaggttc ttcaaaaggg ccatagcctg
     7681 gttgtccaac gccttcaggt tgccatgtac gccatttact gccgtatcag gataatcatc
     7741 atctaacacg ctatcagcca actccataag ctccagctca caagctacca gcttatccag
     7801 caagctatca aagtcttctg actgtttgag ttgttgcacg cgctccagtt tgtaatcttc
     7861 tttgatttca ttttcttgcc cctggtgcgt gtaataatct ttaaacccgt cacaaattct
     7921 tttaaagatc ttacttagtt tcttatcttc tgcatactcc agcactagct gacctttgcc
     7981 cttaatagtt gcctcaatta ctggcgcgtg ataagtccca aacatataac caaagactgc
     8041 attacttgcc actttggcag tgtcaatgtc ttcaaagtcg taagtgaaag taaaggtttg
     8101 tggtttgtca gaaatagttt ttagtgtcat gttgtttgtc tcctgttctg ttatttatat
     8161 aggaccaata gccctagtgt tgttgtcatg gcctcatagt cgccactagt tgcctctgta
     8221 tatttcacgt caacaacttc aacgcctgcc ataaagtcgt ttacctggtt ttcaaattcc
     8281 tccaggcttt gcttatgttt ctgataaaat agcttgattt tcaatttttt tagctccttt
     8341 tctttaattt gttaccttct ttagtgtttt tgttaccttc taggtaacat agctccgcct
     8401 tactgccaca agggtttaga ccgctttgtt accatgttga ccttctttct aactccttac
     8461 ccttatatat ataaatactg cttttttcct atatagagag ttaaaaagaa ggtaacaagg
     8521 tcaacataac agctataaag ctatatatat caagggtcta ggtgcgttac cttctttcta
     8581 aacaaggtaa caagaagggc aacaattttt gtaaaatcct agtaactgca agggtttagg
     8641 ccatcaaaag aaggtcaact ttattctttt tttgttatag cgtgatttac tctccccagt
     8701 tttggcctct caaactccaa cggatccagt ttgtcataat cttcaacctt aacacgcgct
     8761 ttttttagtt ggtacttatt tggcgttaac tgctgtaagt gcctgattgt ctccttacca
     8821 gcaccgtaaa catttggctt aggtattccc atatcttcgg cataatgctt caaggatctt
     8881 gtagcgataa aaacgggtac tacgtccagc tcgtgccaac ctctttccat gtactcatgt
     8941 tttacccaag ataacaagta atcattatct tcctggtact cctctagcaa gcctttgact
     9001 gcctgcggtt cgataaaatg agtaaatgat ttctggttga tagctttata aagggcgtac
     9061 tctaatacct ctttattggc caaaaaatca ttttttatcc agggcttttc tttctcaccg
     9121 ttaaagtcag cattgaaggg gacaatcata atacgcctat accagccctt tgtcttattt
     9181 ccaccgttgg ggatatagtt tcctgagaag atattaaaga gtttgaaggt cgcttcaaaa
     9241 gctgggcgcc cctttggatt gactagcacg gtgtccccgc tggtaatact cattaggtca
     9301 gacggatttt ttaagtattc attaggtgcc tcgtctccaa tattgcaaac tttacctact
     9361 agcgtttcca ggttatgctt ttcagcaaac tgtacgggct tcaatgctga tacgttgctt
     9421 tctcctatca gattgataag gaaccgctga aatgtccctt ttccgttgtt accgtccccg
     9481 taaaagatag caaacttatt ccgtgtatgg ttggggttga tagcctccag gataatctgc
     9541 caaaacaata ttaccagctc actatcgttg caagcgattg agtttaacca atcgtcaaat
     9601 gtctttcctt ccctatcggt tgggatccgc ttaggtgcgt ggtaagctgt gctgatttta
     9661 cttgtaatca catatttagg gctgaaagga agtaactctt tagtccttaa gtcaataatg
     9721 ccattctgta cggggataag gtaggcgctc tccagcggtt tctttatcct tgtcaatgtc
     9781 ctaaccatta gcttaatctg gggccatttc ctgggcttaa tcctcacatc aaaagtctta
     9841 caaaatcggt taaataggtc attactagcc gtatatatgc cctcatctaa atcatatata
     9901 tagagtaggc tataatcagg tacattgctt ttgctgataa aagtaaaggt gataatttcg
     9961 cttagcattt tggcaactgt gaaaacctgg ggcatggcca ccttttcggt aacgtcccct
    10021 gtactttcgt ttattttggt ttccgtgtgt tcttcccgcc attgttcccc agcttgaaag
    10081 atacggtttt ccaattcctt cattgtcctg ggcggttgct cattttcacg cgcctctaag
    10141 atttcacttt ccaggttttt caattcttcc ttttctatgg ttctatcctc gctttctaaa
    10201 ttctgctctt gctatacttt caaaagtcct atctagctcc ctctctggta aggggttagc
    10261 tgtcacgctg ttagcgatct ttgttaattc gtaagctgtt tctatatcac aatcaaccca
    10321 cttattaaag agtagcccca caaagcgcgt gagtgccacg ttacgccctc cctcgtctcc
    10381 aaagccattg aaaagcgtat ctatgaccct catagtgata gaccgctgac cgcttgcccg
    10441 tggtgtgtac gtctgcggtt ttactccctg gccacttgtt cggttttgtc ttgattttgg
    10501 gactggataa tctaggccat gctctacgat tttttgatag tctgctgggt ctcctgttgt
    10561 gactggtaga ccttgtaact gtgaccaggt taaactggcc atatcaaaag gtagccctat
    10621 cttatccgct atctccttga ctacctgctt ataggtttcc tcattcataa cgcccccagg
    10681 ctttaccaca agcctaaaac gggggctttc tggggtgtgt ttgattgttg ggtacaagat
    10741 ataggaaaag ccaaacaaag ctctagaaac agcttctata aagccctggg ctggtccctt
    10801 aatctcatca taatcaagga aaatcaaatc acgatatacc aggctgatat tattccgctt
    10861 gtagctccct gttttctctg ctgtgatttt tccactcaaa caataaggcg cctgggttct
    10921 tttgtattcc tccaggtcag caccttcagg gactaccagg ggcttaaagc gctcaatata
    10981 ctggaatggc tccatcttat caaacagata gacaaggtta ctttgaaagc ctctagcctc
    11041 gtaaattgcc acattatcgc ccctttctac gtttcttctt cagcttttta agcctttgct
    11101 gttcctttag ctggtccagg gtcggcctgc gatctttgta aatcttttca tcatgatagt
    11161 gcccgccacc ttgtgcgggg tgcatattat atcttcccat tttccacccc caaaaatatc
    11221 aaaacatcac tgaccctata aaagattttc ctagtgtctt ctagtggggg ctggcaacgt
    11281 cttagcccat tatcttccca acgttttaag gtcttagcct ttatgcctag ttcatcttta
    11341 acctgctggg ctgtgattag ccctaacagt cttggtgggg tttgctcacg cgcctccagg
    11401 taactttcta ccagctccag cactccctgg gttagatcct gttcactttc tttacttagg
    11461 ctaaacattc atatcagccc ccttcagtaa tttcttatag ctttccaggt ctgctttaat
    11521 cagcacgtct aggcgtttac cttctgtgtc atattgggcc ttcagttctc ggataccttc
    11581 caggcgctcg gtgtcattag ctgggatata gtagccacta actaggccac gtttggccac
    11641 aatagggacc ccatggcgga caataaggcg gtgaatgttc tccctcaatg tcctaatgtc
    11701 caggcctaac aattcagcaa tataccgccc tgcgcgtgga ttatctgcac ccacgggaat
    11761 aagccttaaa attctttctt caagttcggt catgtatctc ctccttagtt gtaacgtctt
    11821 ccagccagcc aaatataagc gccatagtta gggttaagct gttggcttgc tggttcttcc
    11881 tgcttgtctg gtagctctat aatctcgcta tcgttgtaaa atcggtatag ctcataggcc
    11941 aaaagaacca acgtgatcaa gataaaggct agatattgcc ctggtgttaa atcaagttca
    12001 ttcatggttt aactccttac ggtattcact ggctatgtca caatgctctg tgattagttt
    12061 ttttagcgcg tggtttgctg tgtgtagaat tgggaaagtt tttggaccat cttcagtact
    12121 ggccaactct aaaacctcca taatgtcatt taattctcca caaagtccct catagtcaac
    12181 taggatatca ttagttttat ctgtcatact aagcctcttt ctttcaagtc tttataaatc
    12241 aaactacgta agtatgtcca agttgaaact gttgaatcga taattccatt gcttagatta
    12301 ttttctttta tagctttatc taagaaattg aatagtaacc agtcaggggc tttttcatat
    12361 cgttctgtgc attcgtcatc atatcgcttc atctctccta gtaaattatc caggtttgac
    12421 tgtactacct gttcatggct tgcctctgtc ttcttgtaac gttcggatag cctgtaaaat
    12481 tcaatccaca agttacttat agctgttctg cattcttcag cgattccact cgctccgtta
    12541 tgccctttgg ctatatgcca ctcactcaga atatccagtt tttcttcagt tacttgcaac
    12601 tttgcttcaa aatcttcaaa atactgtttc atgttgtttt tacctctgat ttattatttt
    12661 tctgtgtaat tgcctgctct ggtgcgcgtg cttgttctgt tttagtgcta ttctttacta
    12721 tacaagattt accgactgct aaacgctggg atataatcct ctaagttggc ggactcttaa
    12781 tcagtcggtg ctagttttaa ggggtagcgc cctccgtatg gtcataatgc cctagatatg
    12841 gtataatcta gctattaaat ctttactaaa acccttttaa taacagcttg cctgcttgtt
    12901 aattttgttt tagtttgaaa gtgtgaaagg ctttgctggt tggtccctgt taagcctttt
    12961 ttgttgctct cacgcgctaa aaagttaagt ctattaaact ttttggttat aaaaaatctt
    13021 cgaccttaca attaagagct ttagcaattc tggtaagcgt aaaaagtttc acatcttttt
    13081 cttttccagt ttctaaaaaa gaaataatag agcgagatac ttgcgctttt tcggctaatt
    13141 cttcttggga aagtcgctga atttttcgta tttctgctat ttttttacca ttcaaaagtt
    13201 attcctcctt tatcaaaagt taaatctatt aaacaataga ttataaataa aaggcaatgc
    13261 cttatagatt aagtttagcg cattaaacta attttgtcaa gcgcattaaa caaattaatt
    13321 gatatttttt tgaaaccgtt gtataatgta ctaaacaaaa gcccaggaaa gtaggaaata
    13381 aataatgaaa ataggcgata ttgtaaaaga gtatagaaaa cgcaataagc taactatgca
    13441 agaatttgcc gataaaatcg gtaagacaaa aggatatata tcaatgttag agaaaggaga
    13501 gaatcctcaa actcacaagc ctattgctcc aacgtttgaa actttaagag aaatcgcaaa
    13561 agctatgggg atagaactta ataccctgat tcagaaatta gatggcgacc aagttattaa
    13621 agttaattcg acaagatacg actgggacga cgaagaggaa aacttgcgaa actgggggac
    13681 atacgactgg gacggaaatt tttctccttc tttattccat gaagatattt ttattggaat
    13741 aaaaaacacc ctatctaaca ttgacgaagt cacttttaca cgtagcgata tagagtcatt
    13801 ttattcatct tgtataatcg ataatgtaag gattacagat cgcaaaagtt taatagaata
    13861 cttgaagaaa tcaatcaaag gttttaacga gttggttcat ggtatatctg attttgacga
    13921 gcaatcgtta gatagtggtc tcttgtcagt tcttgctagg gatagaaata aatataaatt
    13981 ttacctaact caattagaac cttaacccac gcgccattat attaaaaatc tgaataacat
    14041 gtttttttca tgtttagtaa attcaaaata gaggttttta gaggtttctg cgcgtgcttc
    14101 cctcgtgctt cagcaagtcc gttaaccttg ccaaaacctt gtcacttttt agggtggata
    14161 aaatggccga ttttcttttt ttaaggcgtc agcaatgtta tttttttaag gtgtctaaga
    14221 ttactatgat acattgctat taagaaatac ataataaaga aagtgttaaa atatggatga
    14281 attaatgcaa caaatggctg ataaattcgg tgatatggtc caggctgtaa tcattgaaaa
    14341 gacaaaaata taaaaaaata aatactagaa ggaaaaaaca tgactgatct aacaacttca
    14401 caaatagaac gacaaaatat tttaaataat tctttagcaa tcaaacaagc tgaagaaatt
    14461 ttaaaagtac caggtttcta ctttgaggat agtttttatt ttacaaattc tcaaatagcc
    14521 agctttttcg atgtcgatat tcggactatc gaaagactgg tagaagctca taaaatagag
    14581 cttactaaaa atggttacca cactttacgt ggggaacaac tagctaattt taaagagaac
    14641 gcttttgcta ccgacacaaa tgtcggtagc aaagttacac aattaagtat ctcatcattc
    14701 agaacgttac ttaactttgc tatgttgtta acaaatagtg acatagctaa gcaagtaaga
    14761 aataccttac ttgatattgt cattaatgtc ttaaccgaga agactggtgg ccatgtaaaa
    14821 tttataaacc aacgtgacaa aaattatctg tcgactgcat tagaagaaga taatgctaga
    14881 aaaatattta caaatgctat tgataagtat gtttctggaa gtaattttaa atatggtcaa
    14941 ttaacaaatg aaatttacaa agcaatcttt aaagaaagag cctcagaata taagaaaata
    15001 ttaaaattga acaaaaatga taatacccgt gcaacaatgt atagtgaggt tctcatagtt
    15061 attgctagtt tcgaaaaggg ggtcgcttat gagattgaac aaaagagtaa gtctttaaat
    15121 caaaaaataa ctaatgctga tgtaattgag ataattcaga aattagcaag tcacccaatg
    15181 caggagcctc atctaatgca tgctagagag aaaatggcaa gtagggatct atcttttaga
    15241 aatgctcgac atgagaaatt agcacaatat atccgtccaa tttctgaaga agactttgaa
    15301 cggtttattg gcgaacaaag taaatctctc tcagaacaaa ttgatgaaca tcgccaagtc
    15361 tttgaaagat tgagggataa ataatgggta caatcaatta tttttttgct gaagaggcta
    15421 ttttactaca tgacattgaa gtgattgaga agatcggtgg tttgcatggt gttaaagata
    15481 aagggagggt atttagtgta tttgagcact tacaaaatga cgattactat ccagactttg
    15541 aaaccaaact tacagttcta gtatttaaca cagttcaatt tcatatgttt aacgatggaa
    15601 acaaaagaag tagtatcgtc tttggcgtta aatttttaac aatcaatcac tttgattatc
    15661 tcattccctt ctttatcgaa acaatggaaa atattgtcct atgggtggca atgggattaa
    15721 ttgatttcaa atttttaaaa gaaattattt cttcaattct ctattatgag gaactcactg
    15781 aacaagtaaa agaaagactt gtgcagatag ctttaaccat agaaaactac aaataaaaga
    15841 ctttctcgta acccctggca tgatataaac ctataacatt ataaaaccct tttaataaca
    15901 gcttgcctgc tgatggaaag gtttatgatc atgaaaataa ctgaagtaaa aaagaaaaac
    15961 ggtgctactg tgtaccgcgc tagtgtatat ctgggagttg accaggtaac aggtaagaag
    16021 gtaaagacca aagtaacggg tcggacacaa aaggaggtta agcagaaagc caaacaagaa
    16081 aaaatagcct tccagcaaga cggctttacc aggtttcaag ctacgtcaat agcaagttat
    16141 caggaattag ctgaactatg gtgggaaagc tacaagcata ctgtcaaacc caacacacaa
    16201 gacaacgtta agaagttact agataaccat gttttgccac tctttggggt ctataagctc
    16261 gataagctga ctacgccact cattcaaagc atagttaaca aactggctga caagacaaac
    16321 aagggggagc ctggggctta tctgcattat gataagatcc acgcgctgaa caaacgtatt
    16381 ttacagtatg gcgtgaccat gcaagctata ccagcgaacc ctgcgcgtga tgtcgtccta
    16441 cctcgtaaca ctcaaaaggc taagagaaaa aaggtcaagc attttgaaaa tcaagaccta
    16501 aaaaagtttc tcgactacct gggagggctg gacctgtcca agtacagaaa tctgtatgaa
    16561 gccaccctat acaagttctt gctggccact ggttgccgta tcaatgaagc cctagcgctt
    16621 agctggtctg atattgacct ggagaatgca accatcagca ttactaagac actaaaccat
    16681 ctagggcaaa tcaatagccc aaaatcaaaa gcaagctatc gggatataga tatagaccag
    16741 gcgactatta ccatgctgaa agcctaccag cttagacaaa ttcaagaagc ttggaagtta
    16801 gggcgaactg aaacagttgt attctctgac tttatccatg attacccaag taacaaaacc
    16861 ctgggtacac gtctaaaaac tcggtttaaa cgtgctggag ttcctaacat tggctttcat
    16921 ggtttccgcc atacccacgc tagtttactg cttaactctg gaatacctta caaggaacta
    16981 caataccgcc taggtcattc cactctatcc atgaccatgg atatttatag ccatctctca
    17041 aaagagaacg caaaaaaagc cgtctcgttt tacgaaacag cactaaaagc cctctagggg
    17101 gagcaaaaag gggagcaaac actgaaatca acgatttaag acaaagcaaa aagcccactg
    17161 ttgtaggctt cttacagtat aaagtcttat cttaaagcat tttgttatag aattcaacga
    17221 caagtgcttc attgatttct gggttaattt catcgcgttc tggaaggcga gtcaatgaac
    17281 cttcaagttt ttcagcatca aatgatacga aagctggacg tccaagagta gcttcaacag
    17341 cttcaaggat tgcaggtact ttcattgatt tttcgcgaac tgaaatcact tgacctggat
    17401 caacgcggta tgaagggata tcaacgcgtt taccgtcaac aaggatgtga ccgtggttaa
    17461 cgaattgacg tgcttgacga cgagtagttg ctaaacctag acggtaaaca acgttgtcaa
    17521 gacgacgttc taaaagaacc ataaagttga aaccaagagt tccttctttg atttttgtag
    17581 cttgaacgaa caagttacgg aattgttttt cacctaaacc gtatgagaaa cgaagttttt
    17641 gtttctcagc taactgcaaa ccatattctg agagtttgct acggttgttt ggaccgtgtt
    17701 gaccaggaac gtagttacga cgtgccaatt ctttacctgt gcctgtaagt gataaaccaa
    17761 ggcgacgtga ttgtttccat gatggaccag tataacgtga catattacat gtcctcctct
    17821 aaattttttg aggaaataac ggtttaaaaa atcctgattc gtgcaggggg ttttcgccta
    17881 aacagcaaag gttacttgaa tagataacca cctgttgacg agcttcatat ttttctgctg
    17941 ttatttcgca caaagaacag tttaccataa gaaagttgtt ttgtaaagtc agtctatcta
    18001 tcatctgatg atcagtttaa tattttaagg tcagatatga gacgaaccac cactgatgaa
    18061 ttaagaagac tatattataa gaagttatag ttatggtaat aaagacaact gtcattaaca
    18121 aaaaataatt taaatgctaa tttgcagttc ttaaaccttg actgtttttt tcttagctct
    18181 ctatcaaaag cacttcactg gaaactctta atggctctga aatggctagt atattgtatt
    18241 tatcagggga ggtttactcg ttttttaact tcaagatagt tttaccggat acttcaagct
    18301 cctctattaa ttacacttgt gtcaaaactt tatttcacga taatctttta accttagtac
    18361 taagatcatt tgcttaacca tggtgaaaac ctcttttttc cttcaatcta acctaaaaat
    18421 attatctttt ataggaattt tttcaaaata aaaagaatac aggcagaata atcttctatc
    18481 gctaataatt atatcaattt attgtaaaga aaaagcctct atgaggcaaa aatcaatcta
    18541 aataacgaat taatgttttt tctgtcaaaa tatctgaata ggtgtatgat tcgacataag
    18601 aattatcaat tgctcctgga gtatcagagc tatcactata ctcaatgata aagagtgaac
    18661 tgtaaacttc aataagccta ccaattttat ttttttcccg tttccgtcca ttctcaaggg
    18721 ttaattctac taactgtcct tcatgggctc ttatgtcctc tttaattttt ttcatttttg
    18781 caacatctgt aaatgcatcg ctcatttttt gtctctcttt cttatctttc ttcaaactgg
    18841 gctatacttg agaatttgtt gtattctttt tggaacatca gtttgactgt tccacgcgcc
    18901 ccagctctat ttttctcgag gataacttca attgtgttat cttcaacagc ttcttcagca
    18961 tcatcacctt ctttacggta ataatcgtcc cggtataaga aggctacaat atcggcatcc
    19021 tgctcaatag atcctgattc acgaatatct gataaaactg gtcgtttatc ttgcctttgc
    19081 tcaacgccac gagaaagctg acttagggca ataactggta ctttcaattc tttagctagg
    19141 attttaagct gtcttgaaat atctgaaacc tcttgctgac gattttcggg tttagttcct
    19201 gtaatcaact gtaagtagtc aattacgata agacctaaac caccatccac ttcttgagac
    19261 aatttccgtg atcttgcgcg gatttcagta attttaatcc cgggcgtatc gtcaatataa
    19321 atcggtgctt ctgccaaagc tccctgagca attgttacat tattccagtc ctgatctgtg
    19381 agttgccctg ttcttaaact gtgcgaatca accattcctt ctgctgcaag catacgatct
    19441 actaaacttt cagcacccat ttccaaagaa aaaatagcaa cagtcttttt ttgcttagtc
    19501 cccacatttt gcgcaatatt aagaacaaag gcagtcttcc ctactgctgg ccgagcagct
    19561 aaaataacta attgatctgg gtgtaaacct gttgtaatct tgtcaaggtc tctaaaacca
    19621 gttggtaaac ctgtaacatt tgaagtctgc ttagaacgtg cttctaaagc ctcgtaatta
    19681 acttttagca catctgaaat tttgcgaaac ccactacgat tactatgttc attgagttca
    19741 attaaagctc tctcaactcc agcgataacc tcttctggtt ttaaaatttc atcataagct
    19801 aggttgacag aatctgtcaa cctagcaata atatcacgca acatagcttt ctcagctaca
    19861 attttagcat aatattctgc attagcacta gttgggacac tattaactag ttcaacaata
    19921 taggataagc caccaatact ttgcagatca tcttgatcat ctaggattgt tcttatagtg
    19981 gttgcatcaa tggcatcatt acgatcgctg agagtaatca ttgcccgaaa gataatttta
    20041 tgagcgtact tataaaaatc gtctggactg ataaattctc tcactgcaat cagcttatca
    20101 ggtgagataa agattgaccc aagaacagat tgctccgcta gtaaatcttg gggttgaact
    20161 cgtaattcag ctacttcagg caacctcata acctccaaat cttgtgatgt tttttatatt
    20221 atgcttctgt gatagccaat ttaatctcag ctgttacttc cttatgtaat ttcacaggaa
    20281 cttcaattag accaatggcg cggataggat gatctaaaac aatatgacgt ttatcaactt
    20341 ttacaccaaa ttgcttttgc aattcttctg aaatcttttt agctgtgatg gaaccaaatg
    20401 tacgtccatc tggaccaact ttttcttgaa attgaacacg tgttttgtcc tcatccaaaa
    20461 cagccttgac agcttgagct tctgctaata tttcagcttg agctttttct tcagcttttt
    20521 gttttccttt taattcaccg atgctttgac tagttgcttc tttagctaaa tttttcttaa
    20581 taaggaaatt ttgagcatag cctgttggga cctctttgat ttctcctttt ttaccttttc
    20641 cttttacatc tgctaaaaaa ataactttca tgattctact tctcctgttt ctttcattgt
    20701 catattaata gttttcaata ataagtgctt cgcttgggga agactgatat ccgttaactg
    20761 acaggcagca agattaaagt ggcctcctcc acctaatttt tccatcacac gttgaacatt
    20821 gattttacta cgacttctag ctgaaatagc aatcttatga gaagctgttt caactaatac
    20881 aaagctagcc tcaacgtgag ccattgacag tatcgtatct gcagctttac tagcaataac
    20941 attgctataa agatgatttt tttctcctgc agctacaatg atactgtcac caagacgttc
    21001 tccttgtaaa ataatttcat ttatttgctt atattcttca aaatctgttg cggatatatt
    21061 ttgaatttca acactatcac ttcctttact tcttaagtaa ctagcgacat caaaggtacg
    21121 acttgtcact cgcgtagaaa aatttttagt atcaagcata atacctgcca ttaaaacact
    21181 ggcttggatc ttatttaaac gttttttagc attttgaaat tgaattaact cagtgacgag
    21241 ctccgcagca ctacttgctc cactttcaat aaaagttaag atagcattat caggaaaatc
    21301 atcatctctt ctgtgatgat caactacaat aacattttga aactgttcat aaaattcttt
    21361 agaaagtgtt aaagatatct tagaatgatc aaccattact aaaagtgatc ttggagtcac
    21421 taaacccatt gcttgagaaa cactgattag acgagtcttt ccgtcagcct gcaatcgctc
    21481 aatagccctt tcaatatctg gactcatctc atctggattg taaacggcaa aactattttc
    21541 aataatgtta cctgcgaaaa attgcatacc aacagctgaa cctagtgcat ccatatcaag
    21601 tttcctatgt ccaacaataa aaacattgtc caccatcttg attcgatctg aaatagctgt
    21661 catcatagca cgggtacgtg ttcttgaacg tttaactgta gaaacagacc ctcccccgaa
    21721 ataaattgga ttcgtatgat ccgcattttc acgaatgaca atctgatcac caccacgaac
    21781 aagcgcaata ttaagattct caagagctac ctgtccaatc tggctatgat tttcttcacc
    21841 aaaagaaatt cctatgctga gtgttaaagg gcgttgagca tcttgagctt ctttacgaaa
    21901 ctcttctaag acagaaaatt tattatccat caagtcattt aatgttttaa agtctgtaaa
    21961 gaaatagtag cgatccatat taacacgacg gtaaaaaatc cgttttgact ccataaactc
    22021 atcaatgaag ttagctacaa atgaattaat ttttgaggta tctgcatctg ataaatcatc
    22081 agtgatatca tcataattat caaccgaaat aatgccaaca accggtctta acatactagc
    22141 atcagctaat tgcctgtttc ccacaaagct atcaaaaaaa taaaaaattc ctgatgatac
    22201 atcaatataa gaagtgtatt tattaccaga aacttcaaat gtttgagaaa tatcttcacg
    22261 acgtttttcc gtaataattt gctgaatcaa actgttttgt ataaaaccct cttcagttgt
    22321 aaaaattaat tctgcataag gattatacca ttctacagcg ttggtctctt gatcaaattg
    22381 aactactcca acaggcatat tatcaagtag cgtttttagg ttatcttctg tttgttcatt
    22441 taagagctca atatgagcta agtctgataa ttgataagct tctttttgat accataaaag
    22501 agcaacaaca aatagcaaaa cgagaaaaat agctaataat attaatattt ttgattgcat
    22561 aatactgaca caaagtgcca gtagtccaaa taaaatcaat cccatcataa tcaaatgaat
    22621 ggtttcaaaa cgaaattttt tcatcttata acctcttaag cacacattat accataaaaa
    22681 agccctgaaa tacagagctt ccacttgctt tgagattaca atttcatttc catttaatat
    22741 tttcgatgag cttttccgtt tccctctaaa taaatcatca agatactgat gtccgcagga
    22801 ttgactcctg aaatacgact agcttgtcca attgtttcag gattaatttt cttaaatttc
    22861 tgacgcgcct cagttgcaat agaatcaata gcatcccaat caatatttgc aggaatacgt
    22921 ttttcttcca tgcgtttcat cttagcaacc tgatctaaag ctttgcgaat atagccttcg
    22981 tacttgattt ctgtttctaa aagttcaatg attttagcat ctaaatcttc agccgcagga
    23041 ccaacaaaag agactgcagt cgcataatca atttctgggc gacgcataaa ttctttagct
    23101 gtcatagcat ccgtcaatgg tttaaaacca agttcctgca cacgatcgtt ggttgctttt
    23161 actggtttta atttgatact gttcagacgt tttaattcgt tatcaaattg gtttttctta
    23221 atttcgaagg ccttccaacg ctcatcatca accaacccaa tgtcgcgacc aatctctgtc
    23281 aaacgcatat cagcgttgtc atgacgtaaa atcaaacgat actcagctcg cgatgtcaac
    23341 aatcgataag gttccaaggt tcctttggta accaaatcgt caatcataac gccaatatag
    23401 gcatcgctcc gtttcaaaat aagttctggc ttaccttgaa ctttcaaagc agcattgatt
    23461 ccagcaataa gtccttggcc agcagcctct tcatacccag aagttccatt agtttgccca
    23521 gccgtaaaga gtcctgaaat tagcttggtt tcaagtgtgg cacgtagctg gtgaggtaaa
    23581 acaatatcat attcaatagc ataaccagtg cgcatcattt cagccttttc aagtcctttg
    23641 atcgaatgaa tcaaatcttt ttggacatct tctggaagac tcgttgacaa cccttgaaca
    23701 tacacttctt ctgtatcacg cccctctggc tctaagaaaa gttgatgacg ttctttatca
    23761 gcaaagcgaa caatcttatc ttcaatagat gggcagtaac gagggcctac acctttgaca
    23821 atgccagaaa acatcggtgc tctgtaaagg ttctgattaa tgatatcatg actagtttga
    23881 ttcgtataag tcaaccagca gggaatttga tctttgagat aatcagcatc ttttgacata
    23941 aatgaaaaat gattaggttt gtcatcacct ggctgaattt ccgtttgatc gtaattaata
    24001 gaagatgctt tgacacgagg aggcgttcct gttttgaatc tgccaatttc taagccgagt
    24061 ttttttaaat tatctgctaa agttactgat gccaaactat tattaggccc agaagaatat
    24121 ttaagttctc ctaaaataat ttcgccacgc agagctgttc ctgttgtcac tacaactgcc
    24181 ttagccgcaa atttttgtcc tgtggctgtt aaaacaccta caactcgtcc atcttcaact
    24241 agaatatcat caatcatcgt ttggcgaaga gtcaaattag cctgtttttc aaccgtatgt
    24301 ttcatttcac gcgcatacag ggatttatct gcttgagctc ggagagcgcg tacagctggt
    24361 cccttacctg tattaagcat tttcatctgg atataggttt tatcaatatt tttacccatt
    24421 tcgccgccaa gagcatcgat ttctcgtacc actatccctt tggcagatcc tccaatagaa
    24481 ggattacacg gcataaaagc caacatatca aggttgattg ttgccaataa agttctacaa
    24541 cccatacgac tagtggccaa actggcttca acaccagcat gacctgcacc tatgacaatg
    24601 acgtcatagc tttctgtaaa ttcatgtgtc atttttttaa aatcctttat ttcagtctat
    24661 tcatttaaaa tcatacgctt tagtttagcc ttcaatgcgg acaatatgtc ctggccattt
    24721 agccaactcg gtttgtaaaa actcaggaac aagattcatt tgatccagtt gattgattgg
    24781 aatccattca caaacctgtc gcttgcattc tctatcattt ctagtttagg gtcttctaag
    24841 gggcttacca aataatgaaa ttcaatatta tgccagaaaa catcatcgat atcaaaatga
    24901 ttctcaacca caaaagccag ttgattaacc ttagttcgaa taccaacttc ctctaaggtt
    24961 tcacgtaaaa cagtttcatg cgttttttca cctaccaaac ttgtaccacc aatggtgtaa
    25021 tattggtcag ctgcatctct agttaaaaaa ttcttaccat ttctaacaat caagcactag
    25081 ctcgtaaatt aaagttatct gacctctagt gattctaaat tccagtccta ttagccatct
    25141 catttctaga gctaaaccat aaaaagagcc aaaaccctag aagattgcag gacaaaaaaa
    25201 cctacaactt tcatgagctt tgaccatcat tccgattgtt actatctatt ttaaaaaaat
    25261 gattagtgat tgtcaatatt gatttcatca cagaccttta cagtaatgtc aatgttttta
    25321 caactctgtc aatctattgt aatgttttta aaatgattac aaaagtatca ctatgtctaa
    25381 tctagcgagg cgagaaataa aaatgtcatc agtattatca tacgattttt tgatatcttc
    25441 taaagtagta aaatacagat accgttgttt ctaagtctac aagtaagaac gccg
//
LOCUS       DATTYN010000025        25393 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.25, whole genome shotgun sequence.
ACCESSION   DATTYN010000025 DATTYN010000000
VERSION     DATTYN010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25393
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.25"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..218
                     /locus_tag="VB649_001307"
     CDS             <1..218
                     /locus_tag="VB649_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEP1670255.1"
                     /translation="KEKLYTVEIPNPNREGRGHAKFVLERQGNKVFLVKRKSKDCYYN
                     KNSNHLTEQEIRKDFEWAWQFAKEVRE"
     gene            215..436
                     /locus_tag="VB649_001308"
     CDS             215..436
                     /locus_tag="VB649_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670256.1"
                     /translation="MNNLEKIREEKGISDVQLSSVVQKILEEKYIKGLRFEQVNALTI
                     MCELGYIHFDKRLSEVYEQALNSIGDYKK"
     gene            433..825
                     /gene="ssb"
                     /locus_tag="VB649_001309"
     CDS             433..825
                     /gene="ssb"
                     /locus_tag="VB649_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEP1670257.1"
                     /translation="MINNVVLIGRLTKDVELRYTPSQVACAQFTLAVNRNFKNQDGQK
                     EADFINCVIWRKSAENLSNWAKKGQLIAITGRIQTRNYENQNGQRVYVTEVVAESFQI
                     LEKRDNTANTNSLADTMPDYGPEPDLPF"
     gene            839..1117
                     /locus_tag="VB649_001310"
     CDS             839..1117
                     /locus_tag="VB649_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670258.1"
                     /translation="MIYLQGEGIKPEDMTIDMSGVQALQSTIDYINFLESEKNRCYKE
                     LEDNEACIARLKQSNIELTQKVVDVTWKDMRRVAKARLSRRKYGVKIG"
     gene            1114..1452
                     /locus_tag="VB649_001311"
     CDS             1114..1452
                     /locus_tag="VB649_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670259.1"
                     /translation="MKLRIKYLRQALGLTQSAFAAKAHVNKNMIANYESQNSNPSLKQ
                     IEKIALAFNVEPAWLAGWDTKPQIVIKEKIVKVQDPSARIPNDWKNDECGRLIKWKES
                     RKQLYKSCGG"
     gene            1455..1703
                     /locus_tag="VB649_001312"
     CDS             1455..1703
                     /locus_tag="VB649_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670260.1"
                     /translation="MSHITITLEEDILVNLIFAAAQSSCGFDRNIIKENQMWHLDCCD
                     YNQPIYEVLKQINIDDIQDSYNKDYLKEVIEKGKEFFQ"
     gene            1888..2037
                     /locus_tag="VB649_001313"
     CDS             1888..2037
                     /locus_tag="VB649_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670261.1"
                     /translation="MNGYDFMAQHPYLTGFIAVIIGVVVISSIESITKIWRNTDEQKN
                     QEEES"
     gene            2006..2206
                     /locus_tag="VB649_001314"
     CDS             2006..2206
                     /locus_tag="VB649_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670262.1"
                     /translation="MNKRIKKKKAKQAEVKKQMEYEKLIQDLKNVGLDIEDFSDSIYQ
                     TLSVFVDKLSRAFSAFLKEFEK"
     gene            2230..2649
                     /locus_tag="VB649_001315"
     CDS             2230..2649
                     /locus_tag="VB649_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEP1670263.1"
                     /translation="MDQKIIKRLKNLRMIDTEIMSKRQEIAELRSKILKGQQYSDMPK
                     VEKLGNGNEDLNIKIIDDTRIINEDINKLYKERQVLTTAINNLDDALERNVIRLFYIN
                     RYTWNEIAAEFNCSVRTAHNIRDSGVKNLSKVLHTFT"
     gene            2744..3307
                     /locus_tag="VB649_001316"
     CDS             2744..3307
                     /locus_tag="VB649_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP1670264.1"
                     /translation="MNLVEPIRDKDDIQAMKDYLLHDSAVSYERRYRNYMIFLTGINS
                     GLRVGDIIQLKVKDVQGWHIRVKEQKTGKTRTFRMTKPLKNAMREYVKDKPLHHYIFK
                     SREGHNKPITTGQVWNIIKEAADFLGIDNIGTHSMRKTYGYHHYKQFKDVAALMETFN
                     HASPMITLRYIGIKQDELDDFQRKFAL"
     gene            3479..3772
                     /locus_tag="VB649_001317"
     CDS             3479..3772
                     /locus_tag="VB649_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670265.1"
                     /translation="MNKKLDKDIFKFLEQHKQSLDDIQQHIYDVIIINRLKNHEVAAM
                     FTSLMRQIMTTEHNAKLLDSLGLDVGKLNPEVLAKIQQILTEEWLAEQGYLDK"
     gene            3769..4098
                     /locus_tag="VB649_001318"
     CDS             3769..4098
                     /locus_tag="VB649_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEP1670266.1"
                     /translation="MNLMTPEILEHLKLLIAEDRVKEFYWTKEWRLIRKVRRKKDSNE
                     CQRCKRDGRYSQAEMVHHKNEVRYHPEQALDLDNTECLCNSCHNKEHPEKLHGYKKKK
                     FDNEERW"
     gene            4220..4567
                     /locus_tag="VB649_001319"
     CDS             4220..4567
                     /locus_tag="VB649_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEP1670267.1"
                     /translation="MAGFLEYPEFDWERDLIVQKKYVKARDDIRITLIRILQKRDKYV
                     EPFKDLVEQYTSLWETSQLLRQDIKLNGVRIAGKKNDSVSLQVNVNKQMMVMLEKLDI
                     SAAEVKSDDGEDI"
     gene            4548..6206
                     /locus_tag="VB649_001320"
     CDS             4548..6206
                     /locus_tag="VB649_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEP1670268.1"
                     /translation="MTAKTSSLCHSGTPHIDDWINDILTEKYKVCKEIKQLAELVLAA
                     IDDPEIYVDSKRADGVIEFINKYRPYELAPPQRFIHAAMNAIRYKKDDSLVFTELFLL
                     CARGFGKNSVASDEALYKTSNRNGISEYNVDIVANNEKQAKTSFKDVYNTIKDSTILK
                     KAYKFSQTLITFKKTKSELTYHTSNARTKDGLRPGLVIFDEIHEYENYKNINVFINAL
                     GKVADATVMYLTTDGYVRGAVLDDYKDIAKDILSTCDYKSGMLPILAKIDSFEEWEDP
                     TCWVKANPMLPYLPTLQKEYQKAFKRAKRSKELFIDFLTKRLNFPIEDTTHGVAEWDD
                     IVAASKPLPDDLIGMECVGAIDYADVRDFIGVGLLFKRGKMRYWLHHTFIVAEALKIQ
                     DFKMDFQIPVSEGIVTIVPGKVMDPKYVAEWFVKMAEKYKIKNIAMDDFRKSVVKEVF
                     ESYGLPIQVIRSGSYTDSKLAPIIDMMFANHEIVFGEDRMMRWYTNNVYVDIDGKGNK
                     TYKKIDPEKRKTDGFMAMVHAMAIEEQLTTPTIKINRRLRSYTT"
     gene            6405..7640
                     /locus_tag="VB649_001321"
     CDS             6405..7640
                     /locus_tag="VB649_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP1670269.1"
                     /translation="MGIMQNFLNFFGGDQSISRDGSQRRIKAYLKEVGQIIQVKEYAL
                     QLCIDKISNALSLASFEIYNKGHPVIGSPMWWLFNMEPNQNQTQNQFMSDLITQMIKN
                     SDGALVIMIDDQFVVAKNYEVIYRAFKPNIYKNVIVAGDYQLNKVFSENEVLHFVIND
                     SKIKSYMDGLYDEYGKLIAGSIRNYNRGNALKIGLKIGSMFDQQFGKNVVETDDEGNS
                     VTEADIILDEMYENRFKAVLSDKDSITPIEEGLEMAEIVKSSGNTKSGAVTTRDITDV
                     VTDVIHFAGDAFSIPRGILQGDVADAEAIRENFVNFAVRPFADVIETEVNRKLYKREN
                     YQLGNKFKIQTNTILVYSPENFAAAAEALERSGIYNPDELRMKLGEEPLNTDWSQAYY
                     VTKNYARADSPEDSEMKGG"
     gene            7644..8360
                     /locus_tag="VB649_001322"
     CDS             7644..8360
                     /locus_tag="VB649_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEP1670270.1"
                     /translation="MTKNIFLSIPKRIEASSQADGTAKLYLAGTVGAWYDGITFKEVR
                     QAMSEISSDTVEVHINSYGGDMFEGIAIKNYLKQLDKTVIVVIDGIAASAASVIAMAG
                     DTIKMPKDTQIMIHNPWTWAAGNAKELRKIADDLEKSQTSIEESYLAHFKGTRDELKA
                     LLDEETSLTAEEAVMLGLADELIEETDVVSKDELISDSEASIRENLIAKYGTEIMSEQ
                     SENESVQTTKGLERFAKLFR"
     gene            8396..9589
                     /locus_tag="VB649_001323"
     CDS             8396..9589
                     /locus_tag="VB649_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEP1670271.1"
                     /translation="MSLKNLDFTSPSMEEARAQLFNALRTDDEVAQKEAMDVFAKGLE
                     KSVNDQVKAAALQYQDGIQDEAILAERGLRRKLTSGERKFFAEAVEKQTISGLSKQFP
                     ETIIEDIYNNLVETHPLISLVDVQHGTVKTKFIYGDATKKRAFWGKIPADIKQILLDS
                     FKELDISASKLSGFIALPKGYFELGPSWLANYVVTFLQEVMAAALEEAIVNGDGQSKP
                     LGMMRKLSGDSGGVYPAKEKVTMVDLKPKTLAGIRAALAKAKTDNGIVSALANPLTYW
                     SKLFPGLAYQTQAGVWVTTQLPTGEQIITTHAVPENDMVFGVLKNYLLVVAADVEITE
                     YKETLAIEDMDLYVAKFFGKGIPKNENAFFVADVTTIEGATVPELEENPAIKPEDTIN
                     PTPEL"
     gene            9604..9891
                     /locus_tag="VB649_001324"
     CDS             9604..9891
                     /locus_tag="VB649_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670272.1"
                     /translation="MSKNVTVEVIEEFIGKVEEHHYHIGDTFETTEERSNQLTGKNDY
                     GRAFVKVIKVAEQIENVTVPQIKEKLDKAGISYDKKAPKDELLKLLQEVEG"
     gene            9911..10204
                     /locus_tag="VB649_001325"
     CDS             9911..10204
                     /locus_tag="VB649_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HEP1670273.1"
                     /translation="MSEVEKLSELDSIKKHLKITWNYEDSEIKDMIEDGKTVINSICG
                     SSDFSVGGEAYTVLKAYCRYGRSGSTAMFEENYKRQLLRLQIQNGLKKFRGDV"
     gene            10197..10583
                     /locus_tag="VB649_001326"
     CDS             10197..10583
                     /locus_tag="VB649_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEP1670274.1"
                     /translation="MCKMDKNAIRQENPELNDGLLEYGKIKTLRDDATAKKTGEGFEK
                     IGSLYFSYQTINARFDSYHVSSLSTVDLKIRCFYVVDFKETMKIKINNDFYEVEGYDT
                     DNKKVYMYIFLRKVGYFDGGSYIETT"
     gene            10555..10926
                     /locus_tag="VB649_001327"
     CDS             10555..10926
                     /locus_tag="VB649_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670275.1"
                     /translation="MVEVISKPLNLEKIVTTIKQTGIPCFDMSIGRDEVYENKTFFIY
                     IDDGELMPSLHANQYHKRFTLMFITRENSLFNELELIENLKLCRLIFDSSEVENGQLV
                     NTEEKAIVRTYYFHQLIKIER"
     gene            10935..11357
                     /locus_tag="VB649_001328"
     CDS             10935..11357
                     /locus_tag="VB649_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670276.1"
                     /translation="MANKATLDFSRSQKLADAMSKIPGKSEEVINRVLLAKGTKEIIQ
                     GIIGFMPVSKRNKKHAKFSNPLKERMFNLGFDIVAKGGAANKKGSYGYLVFPNEGRGK
                     HNPVAQQFFEKGLSEREDIVLDYVLDELIQVQEEILNI"
     gene            11368..11955
                     /locus_tag="VB649_001329"
     CDS             11368..11955
                     /locus_tag="VB649_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP1670277.1"
                     /translation="MTFDPTQQFDAYEITNGQFRKRTKGQLGEAKKLGCTGEISVEAE
                     TYKVTKKCEGKVAREVTIIDKLNITFKGHMPVDMLRESFGLTNADLKEGIYGYGRKSI
                     GAEGSLTFDVFDLGREVKKLIAFPNVAFVDGLKFALSNGGEEIAEVEMNLSGMFDEND
                     FCYYETFEDDLKDESVKTGWSKTFEPKLVKKVAEL"
     gene            11976..12347
                     /locus_tag="VB649_001330"
     CDS             11976..12347
                     /locus_tag="VB649_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670278.1"
                     /translation="MLQEQLTLINEIELTNGQTVPINTRISLLDFQRAQREGLMSKHM
                     LNDMIARRKGNSAFNANDYLNASFVAYRSAGGAMTKEEFQAVCPFDLELLGTIFGQIM
                     TGGKPVEKSKFQASFEKATKK"
     gene            12383..12541
                     /locus_tag="VB649_001331"
     CDS             12383..12541
                     /locus_tag="VB649_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670279.1"
                     /translation="MINWNDVSLNDVICYYAFVFDLDISLVLEFSVHDLDEIALCKLA
                     IENWKKSE"
     gene            12615..15851
                     /locus_tag="VB649_001332"
     CDS             12615..15851
                     /locus_tag="VB649_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEP1670280.1"
                     /translation="MAGKSEVKVTYKVLNSEFNKGISEMNAKVTTLNKEFRLQQEQLR
                     LTGSETDKLESKLSKLSSEYEIAQQKTKLTEQALKEVTRLTGENSKETQTWTNKLLDA
                     KRNEEYLKNAIEQTTNALNKEKQATSEAVRASEECKSKLAALKNEQENLAQSADKIKA
                     KYDLERAALGVNASESDKLKIKKRELAEQMENTGKQVQNLEKQLELAKAEYGESSQEV
                     NKLETELLQSKTAFQQYANEAKLASDSIGQFGEKAKQIGSKLTSVGKGLTTGLTVPII
                     AGAGIAVKAASDFESAFAGVMKTNDEVRNANGKVVISYDDLRNGIRNMAKEIPASTTE
                     ISAVAEAAGQLGIKTENVLGFTRTMIDMGQSTNLSAEEAANAMARLANITQMPQDKFD
                     ELGSTIVSLGNNFATTESEILDMGLRLAGTGHLVGLSEAQILGLSAAMSSVGINAEAG
                     GSAMSRVMQKVNTAVLEGGESLTNFASIAGASADEFATMWKERPQDAIVALLKGLGRI
                     KDEGGNVTGTLKDLGIESTQEIDAMQRLAGAGDLVSKAFDKSTEAFKANTALSEEAQK
                     RYETFQSKLQIVKNKLTDIAIEFGGPLMDALSGALDAMEPLFDFLSDLAKGFADLPKP
                     MQQTIMIITGIIAALGPILIIIGQIATGIGAIASLFGAGGALAAVGTFITGTLLPALG
                     SIITVITSWPVIIGAILATIVYYVVTHWEQIKTYLSDFFSWLHELFEPIGEWFGEKWQ
                     AVKDKTVEIWTGLTTWLSETWNSFVETATEVGETLKNVFSSVWNAIVSFLTPIWQGIS
                     ATAQTIFNAVSLFFTTTWNTISSVTKSVWDSVTSFLSGLWNSILATVSSIWTTITTTI
                     SSAWNQISSTTSTIWNTIKSTVGSIWNGIVSTISSAINSITSTISNGFNQAKGVASSI
                     FNSIKDAISNAINGAKNAVTNAISAIRGAFNFQWSLPHLALPHLSISGKFSINPPSVP
                     HFGISWYKNGGIMMNPTVFGRNGNNIMVGGEAGPEAVLPLTTKVLGDIGAGIVKAANI
                     TNKNSYGNNTINVYADVSNDYDLERMIEKIDEGLGHRHAMVARGIGGI"
     gene            15848..16558
                     /locus_tag="VB649_001333"
     CDS             15848..16558
                     /locus_tag="VB649_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEP1670281.1"
                     /translation="MMLDAIIDDFKLSDFGISLAKRPVIPIAEQEVIYHEGIDELDGA
                     LTEYGSLKNRTFDLLCNMLEDVPILAIIRQFRAKLLKDKEYTLSLSDDLGYYYLVKHF
                     KLGNIESEIAEHGEFKISVTADPYDYKVKPIEIIGINSLTVENKGTALALPVIKITGL
                     GTVSLNVGNYSLTIDDLNGEVVIDSEKLDYYDPVRPNVRIIKLHTKAFPKLTIGNNLI
                     TTKGNVTNLSVKFRERFR"
     gene            16555..18606
                     /locus_tag="VB649_001334"
     CDS             16555..18606
                     /locus_tag="VB649_001334"
                     /inference="COORDINATES: protein motif:HMM:TIGR01665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP1670282.1"
                     /translation="MISVFPSTAYTTKELAGVGYPILDLWCKSATLYATMNGEQYIKL
                     VIPHRAKGVKINLLPKDLDIIKIHDMNGDEDYYRVRRPVVTLKTTTIYAEHITYDLNN
                     NFIEDIYIYNRDGQGAMDKISKGTQYDHPFILRSNIKKLSNIRLVRVNPIQALIGSAD
                     NTFLKRYGGELKRQGFTLSINNRIGVDRTDVIRTGKNLTGFECDYDFDNVVTRIMPKG
                     PNGILLPEKYVDSPLINNYPFPLIKDVEYKVEYDGEFNNLSDAEKKQIYDQLRALAKA
                     DFEAGCDLPSAKYKVNFTTLKKTIEYKNYQALENIGLGDMQPVYEGLYDISIKGRVTH
                     IEWDLLNLKYISIELGNFDKGIIKSSLNHQASIKEKIDEAWNTATIALASADGKTTDY
                     YGTDEPKNPQKGDTWFKKNGEEEEIWHYEDVDGKLMWVYKIGTNLISDLENRINQNFE
                     DIGVQIIKINQRTDKELEEFRATLKNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKN
                     RVSETSEESRLTAEILGNNGKTRYNKNLLVGDPNRTKTYDEDYIEVEVNDGGFKRGET
                     YTISFSQTCELLKKVAITLTQINNKGVKLVLTPTKAKMEPQTFNLTKDKEVISVYPLS
                     YTAVLTGDWYKSKQIDLNALEGRELALDMSYKDVVDGNNAAITGQWSDSPQIILDGGN
                     Q"
     gene            18603..19610
                     /locus_tag="VB649_001335"
     CDS             18603..19610
                     /locus_tag="VB649_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEP1670283.1"
                     /translation="MTETIPLRVQFKRMTAEEWARSTVILLEGEIGLETDTGYAKFGD
                     GKNRFSKLKYLNKPDLDAFAQKKETDNKIAKLESIKADKDTVYLKAESKKELDKKMNL
                     TGGTMTGQLQFKPNSHIKHSSSTGGAINIDMSKSAGAAMVMYTNKDTTDGPLMILRSD
                     KDTFDQSAQFVDYSGKTNAVNIVMRQPSTPNFSSALNITSANEGGSAMQIRGIERALG
                     TLKITHENPNVDAKYDENAAALSIDIVGKRGASGNGTAAQGIFINSSAGTTGKMLRIR
                     NKNKDKFYVNPDGGFHSYADSIVDGNLTVKDPTSGKHAATKDYVDKKFDELKKLIQKT
                     D"
     gene            19620..21524
                     /locus_tag="VB649_001336"
     CDS             19620..21524
                     /locus_tag="VB649_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEP1670284.1"
                     /translation="MSRDPTLTLDESNLVIGKDGRVHYTFTAENDNPKVRLASKCLGT
                     AHFNQLMIERGDKATGYVAPVVVEGSGESTGVFKSLEEMLSGLQSINLELTDTKNSKL
                     WSKIKLTNRGMLQEYYDGTIKTEIINSAKGIATRISEETGQKLALINDTIDGIRREYQ
                     DADRRLSASYQAGIEGLKATMRDDKLDLQAEIQASAHGLSQKYDDKLKQLSAKITTTS
                     SGTTEAYENKLKGLRAEFTRSNQGMRTELESKISGLQSTQQATASQILQEIKDRQGAV
                     SRVQQDLNSYQRRLQDAEGNYNSLKETVAGYERRISNQDNTISSNFTQLKSLINQSVT
                     LEKIQSLLRLSGDSIMLAIKDKIPQSKMSGSDIISAINLNSYGVTIAGKHIALDGNTT
                     VNGTFTTKIAEAIKIRADQIIAGTLDASKARIINLNASSIVGLDANFIKAKIGYAIVD
                     MLEGKVIKARNSAMLIDLSSAKMDFNSNATINFNSRDNALVRKDGTHTAFVHFSNATP
                     KGYTGSALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVL
                     IADDFSINRGFKFRPDKMEKVLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTNAVT
                     RELSNYIGII"
     gene            21536..21964
                     /locus_tag="VB649_001337"
     CDS             21536..21964
                     /locus_tag="VB649_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEP1670285.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKIKE
                     YAKDEGDLIDLYAQKDKDGKFVIDERKNIKLADPTKIDELNDLLSELGNEDITIKGHE
                     YSKRFIDFLEYLAESEDEFTSDEIIIIDNILEEFEESKGE"
     gene            21967..22599
                     /locus_tag="VB649_001338"
     CDS             21967..22599
                     /locus_tag="VB649_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670286.1"
                     /translation="MKTLTLSGKPYPIHEGGKVVKTEVRLIGDNGLFIPIELIGDQTA
                     KGADDLIKEGLDAFVREYVTKYAVAESVQKVEELSLAQKEIEQNAEQAKLTAEAAEKQ
                     AKSLELVIAKSQKMANLQAIHLLTSGSKVEPDIYKGLLELIEPAKKGEYQAYDVFTVV
                     DESHEEQAGEGNLVFVHVNEPFTYDKQTLEELESEDKVTVIKYADLVKQD"
     gene            22609..23064
                     /locus_tag="VB649_001339"
     CDS             22609..23064
                     /locus_tag="VB649_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEP1670287.1"
                     /translation="MIINLTSLIHLFGDLVRTVEIHVFTLFVCFDIITGLTKGITNKR
                     ANSTKGLSGIIKHFLVVLLVYTVYPYLILLGAKPLAVAFVLFFIACYGISIVENWGQL
                     GLPMPSFVRSFFEKLKRDTDQFDIATIKIDKTGVKVEAPQVDLKQKEEE"
     gene            23176..24384
                     /locus_tag="VB649_001340"
     CDS             23176..24384
                     /locus_tag="VB649_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEP1670288.1"
                     /translation="MAFLDNIKQGCLDGWVKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVITDIVDRFRAYDSWDESILDHGKFLNDNSRYK
                     AVVGETDYKKACHAIKEAGYATASGYAELLIQIIKENGLQFWDAEVLKSNKEEKMISS
                     QCREVIEFFINLANAGMGVDKDSFAGWQCADVPCYAAKHWFDVDLWGNAIDLLDSAAA
                     VGWEVHRMPTDANPRTGAFFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNPDAL
                     YVGAPARFNTRDFTGVIGWFYPPYQGDTVTQPVRTEPQTSDTIVEIPKTGTFTLDVAE
                     INIRRWPSLASEVVGIYKQGDTVSFDSEGYANGYYWISYVGDSGKRSYMAIGITDKDG
                     NIISLWGKLN"
     gene            complement(24457..24660)
                     /locus_tag="VB649_001341"
     CDS             complement(24457..24660)
                     /locus_tag="VB649_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670289.1"
                     /translation="MIEVLSKEEMMNFINSHSRYQIAQFTGISEQTLANYVKGRTDIC
                     GMSFDKVIKITEYYNSLKNQSLL"
BASE COUNT         8700 a         3910 c         5350 g         7433 t
ORIGIN      
        1 aaaaagaaaa gctttacact gttgaaattc cgaatccgaa tagggaaggc agaggtcacg
       61 ccaagtttgt gcttgaaaga caaggtaata aagttttttt ggtaaaacga aaatcaaagg
      121 attgctacta caataaaaac agcaatcacc tcacagaaca agaaatccga aaagacttcg
      181 agtgggcttg gcagtttgcg aaagaggtga gggaatgaat aatttagaaa aaattaggga
      241 agaaaaagga atttcagatg ttcagttgtc atctgttgtc caaaaaatcc tagaagaaaa
      301 atacattaaa ggtttgcgat ttgaacaagt aaatgcacta acaattatgt gcgagttggg
      361 ttatatccac tttgacaaga gactatctga agtttacgaa caagcattaa atagcatagg
      421 agattataaa aaatgatcaa taacgttgtt ttgattggcc gcttaacaaa agatgttgag
      481 ctacgctata caccaagtca agtagcttgc gcacagttta ctttagcagt taatcgtaat
      541 tttaaaaatc aagatgggca aaaagaggct gactttatca attgtgtcat ctggcgaaag
      601 tctgccgaga atttatcaaa ctgggctaaa aaagggcaat tgattgcaat aacaggacgc
      661 atacagactc gtaactatga gaatcagaat ggtcaacgtg tttacgtgac agaagtggtt
      721 gccgaaagtt ttcaaatttt agagaagcgt gataatacag ctaatactaa tagcttggca
      781 gataccatgc cagactatgg accagaacca gatttaccat tttaggagta attaataaat
      841 gatatattta caaggcgaag gtataaaacc agaagatatg actattgaca tgagtggggt
      901 tcaggcatta cagtcaacca ttgactatat caacttttta gaatcagaga aaaacagatg
      961 ctataaagag ttggaagata acgaagcttg tattgccaga ctcaaacagt cgaatataga
     1021 gctaactcaa aaagttgttg atgtgacgtg gaaggatatg agaagggtag ctaaagctcg
     1081 gttatctcgt agaaaatatg gggttaaaat cggatgaaac taagaattaa atacttacgt
     1141 caagcattag gcttaactca aagtgctttt gctgctaaag ctcacgttaa caaaaatatg
     1201 atagctaact atgagtctca aaattccaat ccaagtttaa aacagattga gaaaatcgca
     1261 ttggcattta atgtagaacc agcatggctt gcaggatggg atacaaaacc tcaaattgtt
     1321 atcaaagaaa aaattgtcaa ggttcaggat ccatcagctc gtattccaaa tgattggaaa
     1381 aatgatgagt gtggtaggtt aatcaaatgg aaagaatcta gaaaacagtt atataagtca
     1441 tgtggaggat aaaaatgtct catattacta ttactcttga agaagatata ctagtaaact
     1501 taatttttgc cgctgctcaa agttcttgtg gctttgatag gaatattatt aaagaaaacc
     1561 agatgtggca cttagattgt tgtgattaca atcagcccat ttatgaggta ttgaaacaaa
     1621 tcaatattga tgatattcaa gattcttaca ataaagatta tctcaaagag gtgattgaaa
     1681 aggggaagga attttttcaa tgaaaataaa gataaacggt aagtttaacg catttctgac
     1741 attcattcta cattttattg tgattgattg gatttggaaa gcgttagaaa ttgctttttt
     1801 agggaaaatc aatggaaatg atgcagactc tattttatta atattgttgt gtttatatat
     1861 tacttggact ttggaatagg agaaggaatg aacggttatg attttatggc ccaacatcca
     1921 tacttaacag gatttattgc tgttattatt ggagtcgtgg ttatcagctc tattgaatcg
     1981 atcacaaaaa tttggagaaa cacagatgaa caaaagaatc aagaagaaga aagctaagca
     2041 agctgaagtt aaaaaacaga tggaatatga aaaactgatt caggacttga aaaatgttgg
     2101 tttagatatt gaagattttt ctgatagtat ttatcaaact ctatctgtat ttgttgataa
     2161 gttgtcaaga gctttcagtg cttttttgaa ggaatttgaa aaataaaaat agttttaggg
     2221 gttgagtgat tggatcaaaa aattattaaa aggctgaaaa acttgagaat gattgacact
     2281 gaaattatgt ctaagagaca agaaattgca gaattaagat ctaagatttt aaaaggtcaa
     2341 cagtactcag atatgcccaa agttgaaaaa ttaggtaatg gtaatgaaga tttaaacata
     2401 aaaattatag atgatacaag aatcattaat gaagatatta ataaactgta caaagaaaga
     2461 caagttctta ctactgctat taataacttg gatgatgctc tagaaagaaa tgttattcga
     2521 ctgttttata taaatcgtta tacgtggaat gagattgctg ctgagtttaa ttgtagtgtt
     2581 agaactgctc ataacattcg agattcagga gtaaaaaatc tttcaaaagt tttgcacact
     2641 tttacctaat ttgcactttt aatttgataa tatgttactg tgaaatactt aaacaaggct
     2701 agccatgttg gctagctttt ctatgtgatt ggaggtgaga gtgttgaatt tagttgagcc
     2761 aattcgtgat aaagacgata tacaagcaat gaaagattat ttgttacatg acagtgctgt
     2821 gagttatgaa cgcaggtatc gcaactatat gattttttta acaggtatta attctggctt
     2881 acgagttgga gatatcattc aactaaaagt caaggatgtt cagggttggc atatcagagt
     2941 taaagaacag aagactggca agacaagaac attcagaatg acaaagcctc tcaaaaatgc
     3001 tatgagagag tatgtcaaag acaaaccact tcaccactat attttcaaaa gtagggaagg
     3061 ccacaacaaa cctattacta ctggtcaagt gtggaacatt atcaaagaag cagctgactt
     3121 cttagggatt gataatattg gtactcattc tatgagaaag acctatggtt atcatcacta
     3181 caaacaattt aaggatgtcg ctgctttgat ggaaacattt aatcatgcaa gccctatgat
     3241 tacattacga tatataggta tcaaacaaga tgaactagat gactttcagc gcaagtttgc
     3301 gctttgattt ttattttgag aagttaagtt caatatatcg tgtaatcact gaattcattt
     3361 tctgcgtagg tttagaaagc ttatattata ggctgtttaa ctaaagcatg gaattagaga
     3421 gaatataaga tatatcgaat ttatcagtaa taaaataaag aaagcgagga aaattgttgt
     3481 gaataaaaaa ctggataaag acatttttaa gttcttggaa caacataaac aatcactaga
     3541 tgatattcaa caacatatct atgatgtcat tatcattaac cgattaaaga atcatgaagt
     3601 ggctgccatg tttacttctt tgatgagaca gattatgacc acagagcata atgctaaatt
     3661 attagacagt ttaggtttag atgttggtaa actaaatcca gaggttctag ctaagatcca
     3721 acaaatctta acagaggaat ggctagctga acaaggttat ctagacaaat gaacttaatg
     3781 actcctgaaa ttcttgaaca cttgaagttg ctgattgcag aagatagagt aaaagaattc
     3841 tactggacaa aggaatggag actcattcgt aaggtcagac gcaagaaaga tagtaacgag
     3901 tgtcaacgct gtaagcgaga cggtcggtat agtcaagctg agatggtcca tcataagaat
     3961 gaagtcaggt atcatcctga acaagctcta gacttagata acacagagtg tttatgtaac
     4021 tcatgtcata acaaagaaca ccctgaaaag ctccatggtt acaaaaagaa aaaatttgat
     4081 aatgaagaac gttggtaagc cccccggtta aaccaaatag caattccttg ggggagtctg
     4141 gcaacgggag ggggtacctc ggaaaaaata tatcgccaac ttttatcaag aacgaaaaaa
     4201 gttagcagaa aggagaaaaa tggcaggttt tttagaatat ccagaatttg actgggaacg
     4261 tgatttaatt gtccagaaaa aatatgtaaa ggctcgtgat gatattagaa ttacgttgat
     4321 acggatttta caaaaacgag ataagtatgt agaaccattc aaagacttag ttgaacagta
     4381 tacttcactt tgggagactt ctcagttgct taggcaagat ataaaactta atggtgtcag
     4441 aattgctggt aaaaagaatg attctgtttc gttacaggtt aatgtcaata aacaaatgat
     4501 ggttatgcta gaaaaacttg acatctccgc agcggaggtg aagtcagatg acggcgaaga
     4561 catctagttt atgccacagt ggaacacctc atattgatga ttggattaat gatattctta
     4621 cagaaaaata taaagtctgt aaggaaatca aacaattagc tgagcttgtt ttagctgcta
     4681 ttgatgatcc agaaatttat gtcgatagta agcgagcaga cggtgtcata gaatttatca
     4741 ataagtatag gccttatgaa ttggcacctc ctcaaaggtt cattcatgct gctatgaatg
     4801 ccattagata taaaaaagat gacagcttag tatttactga gttgtttttg ctttgtgctc
     4861 gtggttttgg aaaaaatagt gtagcttctg atgaagctct ctacaaaaca agtaatcgta
     4921 atggtatatc agaatacaat gttgatattg tagccaataa cgaaaaacag gctaagacgt
     4981 catttaaaga tgtttataat accatcaaag attctacaat ccttaagaaa gcttataagt
     5041 tttcccaaac tctgataacg tttaaaaaga ctaaatcaga acttacttat catacttcta
     5101 atgcccgtac taaggatggc ttaagaccag gtttagttat atttgatgaa atccatgaat
     5161 atgaaaatta taaaaacatc aatgttttta tcaatgcgct tggtaaagtt gcagatgcaa
     5221 ctgtgatgta tctaacaaca gatggctatg ttcgtggagc tgttcttgat gattacaaag
     5281 atattgcaaa ggatatttta tctacatgtg attacaaatc tggaatgtta ccaattttgg
     5341 ctaagataga ttcttttgaa gaatgggaag accctacttg ttgggtaaaa gcaaatccaa
     5401 tgttacctta tttgccgaca ttgcagaaag aatatcaaaa ggccttcaag cgtgctaaac
     5461 gcagtaaaga actatttatt gactttttaa caaaacgttt gaattttcca attgaagaca
     5521 caacacacgg tgttgcagaa tgggatgata ttgttgctgc tagtaagcca ttacctgatg
     5581 atttgattgg tatggaatgt gttggcgcta ttgattatgc tgatgttcgt gactttatcg
     5641 gtgttggtct attatttaaa cgtgggaaaa tgcggtattg gttacatcac acttttattg
     5701 tggcagaagc attaaaaata caagatttta aaatggattt tcagattcct gtgagtgagg
     5761 gtattgtaac gattgttcca ggtaaggtaa tggatccaaa atatgttgca gaatggttcg
     5821 tcaagatggc tgaaaagtat aaaatcaaaa acattgccat ggatgatttt agaaaatcag
     5881 tcgtgaagga agtttttgaa agctatgggt tgccaattca ggttatcaga agtggttcat
     5941 atactgattc taagttagcc cctattattg acatgatgtt tgcgaatcat gagattgtat
     6001 ttggtgagga tagaatgatg cgctggtaca caaataatgt ctatgtagat attgatggta
     6061 aggggaataa aacttacaaa aaaattgatc cagagaagcg taagacagat ggttttatgg
     6121 caatggtaca tgctatggcg atagaagagc aattaacaac accgacaatt aaaataaata
     6181 gacgcttaag gagttacact acgtgataaa tgaaaatatg aatttacttg ctaatactaa
     6241 taacacaatg ctaaatcctc caattaatcc tcttaaggaa tttattgcgt gtgcatacat
     6301 taatggttca tcaactagtt attcacggtg tgtttattgc catcaaacaa tcaaagatgg
     6361 attttgtaag aactgtcgat acatatgaaa gggggtgaga gaatatgggg attatgcaga
     6421 attttttaaa tttctttggt ggagatcagt cgattagtcg tgatggtagc caacgaagaa
     6481 ttaaagctta ccttaaagaa gttggtcaga taattcaagt taaagagtat gctttacagt
     6541 tgtgtattga taaaatttca aatgctctca gtcttgcatc ctttgaaata tacaacaaag
     6601 gacatcctgt gataggaagt ccaatgtggt ggttatttaa tatggaacca aaccagaatc
     6661 aaactcaaaa tcaatttatg agtgatttaa ttactcaaat gataaaaaat tctgatggtg
     6721 ctttagtcat catgattgat gaccaatttg ttgtagctaa gaactatgaa gtaatttata
     6781 gagcctttaa accaaatatt tataagaatg ttatcgttgc tggtgattac cagctcaata
     6841 aagtattttc agaaaatgaa gtgcttcact ttgtcataaa tgatagtaaa atcaagtcct
     6901 atatggacgg tttatatgat gaatatggca aattaattgc tggttcaatc aggaattata
     6961 accgtggaaa tgctttgaag attggtctta agattggttc tatgtttgat caacaatttg
     7021 ggaaaaatgt agttgagaca gatgatgaag gaaacagtgt cacagaagct gatattattc
     7081 ttgatgaaat gtatgaaaat cgttttaaag cggtactatc agataaagat tcaatcacac
     7141 cgattgagga aggcttggaa atggcagaaa ttgtcaagtc tagtggtaat actaaaagtg
     7201 gtgctgtaac aactcgtgat attacagatg ttgtaacgga tgtcattcat tttgctggag
     7261 atgctttttc tatcccaaga ggcattttac aaggtgatgt ggcagatgcg gaagccattc
     7321 gagaaaattt tgtcaatttt gcagttagac catttgctga tgtgattgag acggaagtaa
     7381 atcgtaaact ttataagcgt gaaaattatc aacttggaaa taagtttaag attcagacca
     7441 atacaatttt agtttatagt cctgaaaatt ttgcagcagc tgctgaagct ttggaacgta
     7501 gtggtatcta taatccagat gaattacgta tgaaactggg agaagagcca ttaaatactg
     7561 attggtcaca ggcttactat gtcactaaaa attatgctag ggctgatagc cctgaagatt
     7621 ctgaaatgaa aggaggatga tagatgacca aaaatatttt tttatcaatt ccaaaaagaa
     7681 ttgaagctag tagccaagca gatggcactg ctaagttata tttggcgggt acagttggag
     7741 cttggtatga tggtatcact tttaaagaag tccgtcaggc tatgtctgag atttcctctg
     7801 atacagttga agtacacatc aattcatacg gtggtgatat gttcgaaggg attgctatta
     7861 agaattactt aaagcaactt gataaaacgg taatagttgt tattgatggc attgcagcaa
     7921 gtgctgcttc tgttattgct atggctggtg atactattaa aatgccaaaa gacacacaga
     7981 ttatgattca taatccgtgg acttgggcgg caggaaatgc taaggaactt cgcaaaatcg
     8041 ctgacgatct tgagaagtct caaacatcca ttgaggaaag ctatttagct cacttcaagg
     8101 gaactcgtga tgagttgaag gcattacttg atgaagaaac tagcttaacc gcagaagagg
     8161 ctgttatgtt aggacttgca gatgaactta ttgaagaaac tgatgtagtt tcaaaagatg
     8221 agttaattag tgattcagaa gcaagtattc gtgaaaactt gattgctaag tatggtacag
     8281 aaattatgtc tgaacagtct gaaaacgagt ctgttcagac tacaaaaggt ttagaacgtt
     8341 ttgcaaaact attccgatag gatttattta ttattttaaa aaaaaggaga caattatgtc
     8401 attaaaaaat cttgatttta cttctccaag tatggaagaa gctcgtgctc aactatttaa
     8461 tgctcttcgt acagatgatg aagttgctca aaaagaagca atggatgtat ttgctaaagg
     8521 acttgaaaaa tcagttaatg atcaagttaa agcagctgct cttcaatacc aagatggtat
     8581 tcaagatgaa gcaattttag cagagcgtgg tttgcgacgt aaattgacta gtggtgaacg
     8641 taagttcttt gcggaagctg ttgaaaaaca aacaatcagt ggtttatcta aacaatttcc
     8701 agaaacaatt attgaggaca tctataataa tctagttgag acacaccctc tcatttcttt
     8761 ggtagatgtt caacatggta cagttaaaac gaaatttatc tatggtgatg cgactaaaaa
     8821 acgtgctttt tggggcaaga ttccagcaga tattaaacaa atccttctag attcatttaa
     8881 agagttagat atttctgctt caaaactttc tggatttatt gctttaccaa aaggttattt
     8941 tgaactagga ccatcttggc tagctaatta cgtcgtaaca tttttacagg aagttatggc
     9001 agctgctctt gaagaagcga ttgtcaatgg tgatgggcaa agtaaaccgc ttggtatgat
     9061 gcgtaaactt tctggtgata gtggaggtgt ttatcctgcg aaggaaaaag taacaatggt
     9121 tgatttgaag cctaaaacac ttgcaggtat tcgagcagct ttggcaaaag ctaaaacaga
     9181 caatggtatt gtttctgccc tagcaaatcc gctgacttat tggtctaaac tatttccagg
     9241 tctcgcttat caaacccagg ctggtgtttg ggttactact cagttaccta ctggtgaaca
     9301 aatcatcaca actcatgcag tacctgaaaa tgatatggta ttcggtgttc tgaagaatta
     9361 tttattagtt gttgctgctg atgtagaaat cacagagtat aaggaaactc ttgcaattga
     9421 agatatggat ttatatgttg ctaaattctt tggtaaaggt attcctaaaa acgagaatgc
     9481 cttttttgtt gcagatgtta caacgattga aggtgctact gttccagagc ttgaagagaa
     9541 tccagcaatt aaaccagaag atacaattaa cccaactcca gaactttaag aaaggaaaac
     9601 cttatgagta aaaatgtaac agtagaagtt attgaagaat ttatcgggaa agtggaggaa
     9661 catcattacc atatcggaga tacttttgaa acaacagaag aacgatcaaa tcaacttact
     9721 ggcaaaaatg actacggtcg tgcttttgta aaagttatta aagtagctga acaaattgaa
     9781 aatgtgactg taccacaaat caaagaaaaa ctggataaag ctggcatttc ttacgataaa
     9841 aaagcgccaa aagatgaact gttgaaattg ctccaagaag tagaaggtta atctttttta
     9901 gggagggtct atgagcgaag ttgaaaaact gtctgagctt gacagtatca aaaaacacct
     9961 gaaaataact tggaactatg aagattccga gattaaggat atgattgagg atggtaaaac
    10021 tgtcattaat agtatctgtg gttcttcaga tttttctgtt ggtggtgaag cttatacagt
    10081 cctgaaagct tattgtcgtt atggtagatc tggaagtacc gcaatgtttg aagaaaacta
    10141 taagaggcag ttgcttcgct tacagattca aaatgggctt aaaaaattta gaggggatgt
    10201 gtaagatgga taagaatgca atccgtcaag aaaatcctga acttaatgac ggtctacttg
    10261 aatacgggaa gataaaaaca ctaagggatg atgctactgc taaaaaaaca ggtgagggat
    10321 tcgagaaaat cggatctctc tattttagtt atcaaacgat taatgccaga ttcgatagtt
    10381 accatgtgtc aagcctttct actgttgatc ttaaaattcg ttgcttttat gtggttgact
    10441 tcaaagaaac aatgaaaatt aagattaata atgattttta cgaagttgaa ggctacgata
    10501 cagataacaa aaaagtgtat atgtatatat ttctaagaaa ggttggttat tttgatggtg
    10561 gaagttatat cgaaaccact taaccttgaa aagattgtca caactatcaa acaaacagga
    10621 attccttgtt ttgatatgag tattggtagg gatgaggttt atgaaaataa aacctttttc
    10681 atttatatag atgacggtga attaatgcca tcactacatg ctaatcagta tcacaaacga
    10741 tttaccctca tgtttatcac cagagaaaat agtcttttta atgagttaga gttgattgag
    10801 aatctcaaac tatgtagatt aatctttgat agctcagaag ttgaaaatgg acaattggtt
    10861 aatacagaag aaaaagctat tgttaggaca tattattttc atcagcttat taaaattgaa
    10921 aggtaaatta ttttatggca aataaagcta ctttagactt ttcaagatca caaaaattag
    10981 cagatgccat gtctaaaatt cctggaaagt cagaagaagt cataaataga gttcttttgg
    11041 caaagggaac aaaagaaatt attcagggaa ttattggttt tatgccagta agtaaacgca
    11101 ataaaaaaca tgctaaattt tctaatccat taaaagagcg aatgtttaat ttagggtttg
    11161 atattgttgc taagggtgga gccgcaaata aaaaaggttc atacggttat ttggtttttc
    11221 ctaacgaagg tcgagggaaa cataatccag tagcccaaca attttttgaa aaaggtcttt
    11281 ctgaacggga agatattgtc ttggattatg ttttggatga actgatccaa gttcaagaag
    11341 aaattttaaa tatataagga ggtcattatg acttttgatc caacacaaca atttgatgct
    11401 tatgaaatta ccaatggtca atttcgtaaa cggacaaaag gacaacttgg tgaagcaaag
    11461 aagctgggtt gtacaggtga aattagtgta gaagctgaaa catataaagt tactaaaaaa
    11521 tgtgaaggta aagttgccag agaggtcacc attattgata agcttaacat tacatttaaa
    11581 ggtcacatgc ccgttgacat gctacgtgaa tcgtttggtc tgacaaatgc tgatttaaaa
    11641 gaagggattt atgggtatgg tcgtaaatct attggtgcag aaggtagctt aacatttgat
    11701 gtttttgacc ttggtaggga agtgaaaaaa ttgattgcat ttcctaatgt tgcatttgta
    11761 gatggcctta agttcgctct gtcaaatggt ggtgaagaaa ttgcagaggt agaaatgaat
    11821 cttagtggta tgtttgatga aaatgacttc tgctactacg aaacatttga agatgattta
    11881 aaagatgaat ctgtgaagac aggttggagt aaaacttttg aacctaaatt ggttaaaaaa
    11941 gtagcagaac tataaggaaa taggagaaat aaatcatgtt acaagaacaa ctaactttaa
    12001 ttaatgagat tgaattgact aatgggcaaa ctgtgccaat caatactcgt atttcattgc
    12061 tagactttca acgtgcacag cgtgaaggtt taatgagtaa acacatgcta aatgatatga
    12121 ttgctagacg aaaaggcaat tctgctttta atgctaatga ctacttaaat gcttcatttg
    12181 ttgcttatcg ttctgctgga ggagcaatga ccaaagaaga atttcaagct gtctgcccat
    12241 ttgatttgga gctattgggc acaatttttg gacaaatcat gactggtgga aaaccagtag
    12301 agaaaagtaa attccaagct tcatttgaaa aagctacaaa aaagtaacta atggctcttc
    12361 tggaaaatct aaaaagactc caatgattaa ctggaatgat gtttctttaa atgatgtgat
    12421 ttgctactac gcttttgttt ttgacttaga tattagttta gttttagagt tttctgttca
    12481 tgatcttgat gaaattgctt tatgtaaatt agcaattgaa aactggaaaa aaagtgaata
    12541 atgcagtgct gagattgcca ttctaaggga atttcagctt tttttatgac taattatagg
    12601 agaaaggagg gaatatggca ggaaaatctg aagtaaaagt aacttataaa gttcttaatt
    12661 ctgaatttaa taaaggcatt tcagaaatga atgctaaggt aacaacacta aataaagaat
    12721 tcagactaca acaagagcaa ttacgactca ctggaagtga aactgataaa ttagagtcta
    12781 agttaagtaa gttatcctct gaatatgaaa ttgctcaaca aaagacaaaa ttgactgaac
    12841 aggctttaaa agaggtcact aggttaactg gtgaaaattc taaagaaact cagacatgga
    12901 ctaataagct tttagatgca aagagaaatg aagagtatct caagaatgct attgaacaga
    12961 caactaatgc ccttaacaaa gaaaaacaag caactagtga agcggttaga gcatcagaag
    13021 aatgtaaatc taaattagct gctttaaaaa atgagcaaga aaatttagcg caatcagcgg
    13081 ataagataaa agctaagtat gatttagaac gtgctgctct tggtgttaat gcctcagaat
    13141 ctgacaagct caaaattaag aaacgtgagc ttgcagagca aatggaaaac actggtaagc
    13201 aagtccaaaa cttagaaaaa caacttgaac tggcaaaagc tgagtatggt gaaagcagtc
    13261 aagaagttaa taagcttgag acagaattat tacagtcaaa gaccgctttt caacaatatg
    13321 ccaatgaagc taagctagct agcgatagta ttggtcagtt cggagaaaaa gccaagcaaa
    13381 ttggtagcaa gttgacatca gttggtaagg ggttaactac tggtttaaca gtaccaatta
    13441 ttgcaggtgc tggtattgcg gtaaaagcag caagtgattt tgaatctgct tttgctggtg
    13501 taatgaaaac caatgacgag gttaggaatg ctaatggcaa agttgttatt agttatgatg
    13561 atctaagaaa tggtattagg aacatggcca aggaaatacc agcaagcaca acagagattt
    13621 cagcagttgc tgaagctgct ggacaacttg gtatcaaaac agaaaatgtc cttgggttca
    13681 ctagaactat gattgatatg ggtcaatcaa caaacttatc agctgaagaa gccgctaatg
    13741 ccatggccag attagcaaac atcactcaga tgccacagga taagtttgac gaacttggtt
    13801 caactattgt gtctcttggg aataattttg caacaactga gtcagaaatc cttgatatgg
    13861 gactacgttt agcaggtact ggtcatttag ttggtctaag tgaagctcag atattaggct
    13921 tatctgctgc tatgtcatca gtagggatta atgccgaggc tggtggttca gctatgagtc
    13981 gtgttatgca aaaagttaat acggcagttc ttgagggcgg tgaatcttta acgaattttg
    14041 caagtatagc tggggcaagt gctgatgagt ttgcaaccat gtggaaagaa agaccacaag
    14101 atgctattgt tgctttgtta aaaggtttag gacgtattaa agatgaaggc ggaaatgtta
    14161 ctggaacatt aaaagattta ggaattgaat ccactcaaga aatagatgcc atgcagcgct
    14221 tagctggtgc aggtgattta gttagtaaag cctttgataa atctacggaa gcttttaaag
    14281 caaatacagc actttcagaa gaagctcaaa aaaggtatga gacatttcaa agtaagttac
    14341 agattgtcaa aaataaatta acagatattg ctattgaatt tggtggtcca ttaatggatg
    14401 ctctatcagg ggcgcttgat gccatggaac cattatttga ttttctaagt gatttagcaa
    14461 aaggttttgc cgacttacca aaaccaatgc aacagacaat aatgattatt acaggaatca
    14521 ttgctgctct aggtccaatt ttaattatca ttggtcaaat agcgactggg attggtgcga
    14581 tagctagttt atttggcgct ggcggcgctt tagctgctgt tggaacgttt atcacaggaa
    14641 cattattgcc agctcttggt agtattataa cagtgattac tagttggcca gtgattatag
    14701 gcgctatatt agcaacaatt gtctattatg tggtaaccca ttgggaacag ataaaaacct
    14761 atttatctga ctttttttca tggctccatg agcttttcga accaatagga gagtggtttg
    14821 gtgaaaaatg gcaggcagtc aaagataaga cggttgaaat ttggacaggc ttaacaacgt
    14881 ggctgtctga aacgtggaat tcttttgttg aaacagctac tgaagttggc gaaactttga
    14941 aaaatgtctt tagttcagtt tggaatgcaa ttgttagttt cctaacacca atttggcaag
    15001 gcatttcagc cacagctcaa actattttta atgccgtttc attattcttt acaacaactt
    15061 ggaataccat atcatctgtt actaagtcag tatgggattc agtaacatct ttcctttctg
    15121 gattgtggaa tagcattcta gctactgtct caagtatctg gacgactatc acaacaacta
    15181 tctcttcagc atggaatcag attagttcaa caacatcaac gatttggaat acgatcaaat
    15241 caactgttgg aagtatttgg aatgggattg tatcaactat ttcaagtgcc attaattcaa
    15301 ttactagcac tatttccaat gggttcaatc aggctaaggg cgtagctagt agtatcttta
    15361 atagtattaa agacgctatt tcaaatgcta ttaatggggc taaaaatgct gttacaaatg
    15421 ctattagtgc tatcagagga gcattcaact tccaatggag cctacctcat ctggccttac
    15481 ctcacttatc aatttctggg aaattcagta taaatcctcc aagcgttccc cattttggga
    15541 tttcttggta taaaaatggt ggcatcatga tgaatccaac tgtttttggt agaaatggta
    15601 ataatattat ggtaggcggt gaagctggtc ctgaagcggt tttaccatta accacaaaag
    15661 tactaggaga cattggtgct ggaattgtta aagctgctaa tattaccaat aagaatagct
    15721 atggtaataa tactatcaac gtttatgctg atgtatccaa tgactatgac ttagaaagaa
    15781 tgattgagaa aattgatgag ggtcttggcc atagacatgc tatggtggct cgtggaatag
    15841 gggggatatg atgttagacg caataattga tgattttaaa ttaagtgatt ttggtatcag
    15901 cctagctaag aggccggtta ttcctattgc agagcaggaa gtcatttacc atgaaggaat
    15961 tgatgaatta gatggagctt tgactgagta tggatcttta aaaaatagaa cttttgattt
    16021 actttgtaac atgttggaag atgtgccgat tttagctatc atcaggcaat ttcgagctaa
    16081 attacttaaa gacaaggaat acacactatc cttatcagat gatttgggat attactatct
    16141 tgtcaaacat tttaagctag gaaatattga aagtgaaatc gcagaacatg gtgaatttaa
    16201 aattagtgta actgctgatc catacgatta taaagttaag cctattgaaa taatagggat
    16261 aaacagccta actgttgaaa ataagggtac agcattagct ttaccagtga taaaaataac
    16321 aggattgggt acagtctctt tgaatgttgg taactattca cttactattg atgatttaaa
    16381 tggcgaagtt gtaattgata gtgaaaaact tgattactat gatccggtta gacctaatgt
    16441 gcggattatt aaattgcata caaaggcatt tcctaaatta accatcggta ataatcttat
    16501 tacaacaaaa ggaaatgtta ctaacttatc tgttaaattt agagagaggt ttagatgata
    16561 tcagtatttc ctagtacagc ttatacaact aaggaattgg ctggtgttgg gtatcctata
    16621 cttgatttgt ggtgtaaatc agcgacattg tatgcgacga tgaacggaga gcaatatatt
    16681 aaactggtta ttccacaccg agccaaggga gttaaaatta atttgttgcc taaagatctg
    16741 gatattataa agatccatga catgaatggc gatgaagatt actatcgtgt acgtcgacct
    16801 gttgtcacgt tgaagacaac gactatatat gccgaacata tcacatacga cttaaacaac
    16861 aattttattg aagatattta catttacaac cgagatggtc aaggagcgat ggataaaatc
    16921 tccaagggga cgcaatatga tcaccctttt attttgcgct caaatattaa aaaattgtca
    16981 aatattcgtt tggtaagagt aaatccaata caagctctaa taggcagtgc ggataatact
    17041 tttttaaaga gatatggtgg tgaattaaaa agacaaggat ttactttgtc cataaataat
    17101 cggataggtg tagatagaac agacgttatt cgaacaggga aaaatttgac tgggtttgag
    17161 tgtgactatg actttgataa tgttgtgact cggattatgc caaaaggccc taatggcatt
    17221 ttattgccag aaaagtatgt tgacagtcct ttaatcaaca actacccatt tccgcttata
    17281 aaagatgttg agtacaaggt cgagtatgac ggagagttta ataatcttag tgatgcagaa
    17341 aaaaagcaga tttacgatca actaagagct ttagcgaagg ctgattttga agctggttgt
    17401 gatttaccaa gcgctaagta taaggttaat tttacaactc ttaaaaaaac aattgagtat
    17461 aaaaattatc aagcattaga aaatatcggt cttggagata tgcaacctgt ttatgaaggg
    17521 ttgtacgaca ttagtataaa aggccgtgtc acccatatag aatgggatct tctaaatctt
    17581 aaatacattt caattgaact tggaaatttt gataaaggta ttattaaatc atctttaaat
    17641 caccaggcaa gtattaaaga aaaaattgat gaagcatgga atacagctac tattgcttta
    17701 gcttcagcag atgggaaaac tactgattat tatggtactg atgaacctaa aaatccacaa
    17761 aaaggagata cttggttcaa gaaaaatggt gaagaagagg aaatttggca ctatgaagat
    17821 gttgatggga agttaatgtg ggtctacaaa attggaacaa atctcattag cgacctagaa
    17881 aacagaataa atcaaaattt tgaagatatt ggtgtacaaa taataaaaat caaccaacgc
    17941 accgataaag agcttgaaga atttagagcc accctcaaaa acctagcgtt accagaggaa
    18001 gcgattaaaa aaatcacaga ggctatcaaa gttgatgaca tcccgtctat taaacaaagc
    18061 tttgatgacc tcaaaaatag agtgagtgag acaagcgaag aatctcgttt aactgccgaa
    18121 attttaggaa ataacggtaa gacccgctac aacaaaaatt tattggttgg cgaccctaat
    18181 cgtacaaaaa cctatgatga ggattacata gaagtagaag ttaatgacgg tggctttaaa
    18241 cgtggcgaga cgtacacgat tagctttagt caaacgtgtg agctactcaa aaaagtagct
    18301 atcacattga cgcaaattaa caacaaggga gttaagttag tactgacacc aaccaaagca
    18361 aaaatggagc cgcagacctt taatctaacc aaggataaag aagttatcag cgtttatcct
    18421 ttgagctata cggctgtttt aactggcgat tggtataaat ctaagcaaat agatttaaat
    18481 gcgttggagg ggcgggaatt agctctggac atgagctata aagatgttgt ggatggcaat
    18541 aatgccgcga taacagggca gtggtcagac agcccacaaa taattttaga tggaggtaat
    18601 caatgacaga aactataccg ctgcgagtcc aatttaagcg gatgactgcc gaagaatggg
    18661 ctcgcagtac tgtcatctta cttgagggtg agataggtct tgagaccgac acaggatatg
    18721 cgaagtttgg tgatggtaaa aaccgattta gtaagcttaa gtaccttaat aaaccagatc
    18781 tagatgcgtt tgcacaaaaa aaagaaactg ataataaaat cgccaaatta gaatcaatta
    18841 aagcagacaa agacactgtt tacttaaaag cagagtcaaa aaaagagcta gacaaaaaaa
    18901 tgaatttgac aggcggcaca atgacaggac aactacagtt taaacctaat agtcatatta
    18961 agcactcatc ttctacagga ggagcgatta acattgatat gtctaaatca gcaggtgctg
    19021 ctatggtgat gtatacaaat aaagatacta ctgatggacc attgatgatt ttacgctctg
    19081 acaaagatac gtttgatcag tcagctcaat ttgtggatta cagcggtaag actaatgctg
    19141 taaatattgt aatgcgccag ccaagcacac ctaatttttc ctcagcactt aatataacca
    19201 gtgccaacga aggcggtagt gcgatgcaaa ttagaggcat cgaaagagca ttgggaacac
    19261 tcaaaatcac acacgaaaac ccaaacgttg acgcaaaata cgatgaaaac gctgcagcgt
    19321 tatctattga tatcgttgga aaacggggag ccagtggaaa tggtactgct gcccaaggca
    19381 ttttcatcaa ttcgtccgca ggcacaactg gtaaaatgct cagaatcaga aataaaaata
    19441 aagacaaatt ttatgtaaat ccagatggcg gctttcactc atatgcagat tcaatcgtgg
    19501 atggtaatct aacagttaaa gatccaacat ctggaaaaca tgctgcgact aaagattacg
    19561 tagataaaaa atttgatgag ttaaaaaaac tcatacaaaa aacagattaa ggaggataaa
    19621 tgagtagaga tccaacacta acattagacg agtcaaatct cgttattggt aaggacggac
    19681 gtgtgcatta cacatttact gcagagaacg acaacccaaa agtcagacta gctagcaagt
    19741 gtctaggcac agcgcatttt aatcagctca tgattgagcg aggggataaa gcgactggct
    19801 atgtggcgcc tgtggttgtt gagggtagcg gtgagtcgac aggtgtgttt aaaagtcttg
    19861 aggagatgct tagtggtcta cagtctatta atttagagct gacagatact aaaaactcca
    19921 aactttggtc aaaaatcaag ctgactaacc gtggcatgtt gcaggagtac tacgatggta
    19981 cgattaagac tgagattatt aactccgcca aaggtatcgc tacacgcatt agtgaggaga
    20041 ctggtcaaaa gctagcgctc atcaatgaca ccattgatgg tatcagacgt gagtatcaag
    20101 atgctgatag gcgcttatcc gcaagttatc aagctggtat tgagggctta aaagccacca
    20161 tgcgtgatga taagttagat ttgcaagctg agatacaagc aagtgctcat ggcttgtctc
    20221 aaaagtatga tgataagctt aagcagctat cagctaaaat cacaacaaca tctagcggca
    20281 cgaccgaggc ctacgaaaac aagctaaagg gtttgcgtgc tgagtttact cgctcaaatc
    20341 aaggcatgcg gacagagctg gagtctaaaa ttagtgggtt gcaatcaacg caacaagcaa
    20401 ctgctagcca aatcttacaa gagattaaag acaggcaagg cgctgtcagt cgtgtgcagc
    20461 aagacctaaa cagttatcaa aggcgcttgc aagatgcaga aggcaattac aactctttaa
    20521 aagagactgt agcgggttat gagcgcagga tatccaatca ggataacact atctcctcta
    20581 actttacaca gctaaaaagc ttgataaatc agtctgtgac cttagaaaaa attcagtccc
    20641 tcttgaggct atctggtgac agtatcatgc ttgcgattaa agacaaaatc ccgcaaagta
    20701 aaatgtctgg cagcgatatt atctcagcga ttaacttaaa ctcctacgga gtaacaatcg
    20761 caggtaaaca catcgctctc gatggcaata cgactgtcaa cggcaccttt accacaaaga
    20821 tagcagaggc tatcaaaatc agagctgacc aaatcatagc aggcacttta gatgcctcta
    20881 aagctcgtat tattaatcta aacgccagca gtatcgttgg tttagacgct aactttatca
    20941 aagctaaaat tggctatgcg attgttgaca tgcttgaggg taaagtgatt aaggcacgca
    21001 atagcgctat gcttattgat cttagctcgg ctaagatgga ttttaatagt aatgcgacca
    21061 tcaactttaa cagccgagat aacgctttag tgcgtaaaga cggtacccac actgcctttg
    21121 tacactttag taatgccaca ccaaaaggtt atacaggttc ggcattatat gcctctattg
    21181 gtatcacctc atctggtgat ggggtcaaca gtgcgtcatc tggacgtttt gcagggctaa
    21241 ggtcatttag gtatgctacg ggatataatc atactgctgc agtcgaccaa accgagctat
    21301 acggtgataa tgtcttgatt gcagatgact ttagcatcaa tcgaggattt aaatttagac
    21361 cagacaaaat ggaaaaagtg ctcgacatga acgacttgta tgcggctgta gtagccttag
    21421 gccgctgttg ggggcacttg gctaacgtcg gctggaatac tgctcatagc aattttacaa
    21481 atgcggtcac tagagagttg agtaattaca ttggtattat ttaaaaggag aaaacatgga
    21541 tttaacgctt aaaaacaaag atttaaacac attatatagt gtactagaca aaatcaaggt
    21601 cacgaacatg cgagcaaacc gcggacgtgc taagctactc gcaaaagtag tcgataaaat
    21661 caaagagtac gccaaggatg agggtgacct tattgatctg tatgctcaaa aagacaaaga
    21721 tggcaagttt gtcatcgatg agcgcaaaaa catcaagcta gcagacccga ctaagattga
    21781 tgagctcaac gacttattgt ccgaacttgg taatgaggac attactatca aaggccatga
    21841 gtattctaag cgttttatcg actttttgga gtacttggca gaatcggaag atgagtttac
    21901 ctcagacgaa atcattatca tcgataacat tttagaggaa tttgaagaaa gcaaaggaga
    21961 ataactatga agacattaac actatcaggc aaaccttatc caattcatga aggcggtaaa
    22021 gttgtaaaaa cagaggttcg cttaatcggt gacaatgggc tatttatccc cattgaatta
    22081 atcggtgatc agacagctaa gggagcagat gaccttatta aagagggact agatgctttt
    22141 gtacgcgagt atgtgactaa atacgccgtg gcggaatcag tgcaaaaagt ggaagagttg
    22201 agcctcgcac aaaaagagat tgagcaaaat gcggagcaag caaagctaac agcagaagcc
    22261 gctgaaaaac aagctaaatc tctggagctt gtcattgcaa aatctcaaaa aatggctaat
    22321 ctacaagcaa tccatctact aacaagcgga agcaaagttg aacctgatat ctataaaggt
    22381 cttttagagc taatcgagcc agccaaaaaa ggtgagtatc aagcctatga tgtctttacg
    22441 gtagtagacg agtcgcacga agagcaggca ggagaaggta atcttgtctt tgtacacgtt
    22501 aacgagccat ttacttatga caaacaaacc ttagaggagc tagagtcaga agacaaagta
    22561 acagttatca aatatgcaga cttagttaag caggattgag gtggttagat gattattaat
    22621 ttaacaagtc ttattcacct tttcggtgat ttagttcgta ccgttgaaat ccacgttttt
    22681 acactttttg tttgttttga cattatcaca gggctaacaa aaggtattac aaacaagagg
    22741 gctaatagca caaagggact atctggcatt atcaagcatt ttttagttgt attgttagtt
    22801 tatactgtct atccttacct cattttgctt ggcgctaagc ctttggcagt tgcctttgtc
    22861 ctctttttta tcgcatgtta tggcatatca attgtcgaaa attggggtca gttgggcttg
    22921 ccgatgccaa gttttgtcag atcatttttc gaaaaactca aacgtgacac tgatcaattt
    22981 gacattgcca cgattaaaat tgataagaca ggtgttaaag tcgaggcgcc acaagttgat
    23041 ttaaaacaaa aagaagagga gtaagatgaa aaaagcaatc acacaaatag ccgtcatcat
    23101 agcgatcata gtgctatatt ttccactggc cgtgattgct ttgattttgg ctccctttat
    23161 aggagaggat ggtagatggc atttttagat aacattaagc aaggatgctt agatggatgg
    23221 gttaaatata aaattctacc atccttgacc gcagcgcaag caatccttga gagcggttgg
    23281 ggcaaacatg ccccacataa cgctttattt gggattaagg ctgatagctc ttggactggt
    23341 aagtcattta atactaaaac ccaagaggag tatcaaccag gtgttattac tgacattgta
    23401 gacaggttta gagcctacga tagttgggat gagtcaattc ttgatcacgg caaattttta
    23461 aacgacaatt cacgctataa ggcagtcgtt ggtgagactg attacaaaaa ggcctgtcat
    23521 gctatcaagg aggcaggtta tgccacagcg agtggctatg cggagctact tatccaaatt
    23581 atcaaggaga atggcttgca gttttgggat gccgaagtct taaaaagtaa taaggaggag
    23641 aaaatgatta gttctcaatg tcgagaagtt atcgaatttt ttattaattt ggccaatgct
    23701 ggtatgggtg ttgacaaaga tagttttgcg ggctggcaat gtgcagatgt gccttgttat
    23761 gcagcaaagc actggttcga tgtcgacctt tggggaaatg cgattgactt actagatagc
    23821 gctgctgccg taggttggga agtccatcgc atgccaacag atgcaaatcc acggactgga
    23881 gcattctttg tccaatcagt gccgtatcat caatttggac atacgggaat tgttatcgag
    23941 gatagtgacg gttacaccat gcgcactgtc gagcaaaaca ttgatggcaa tcctgatgct
    24001 ttgtatgtcg gtgcaccagc tcgttttaac actcgtgact ttactggcgt gataggttgg
    24061 ttttaccccc catatcaagg ggatacagtc acgcaaccag tcagaaccga gccgcaaacg
    24121 tctgacacta tcgtagagat accaaaaaca ggtactttta ccctagatgt cgcagagatt
    24181 aatattagac gctggccaag ccttgccagc gaagtagtag gtatctacaa gcaaggcgat
    24241 accgttagct ttgatagtga gggttacgcc aatggttact actggattag ctatgttggt
    24301 gactcgggta agcgaagcta catggctatt gggataactg acaaagatgg taacattatc
    24361 agcctttggg gtaaattaaa ttaaattaga taagacaaac gccctcgctt tgcgggggcg
    24421 gttttctgtt ataacggact ttcttcaaaa tgtcggttat aatagacttt ggttttttaa
    24481 actattatag tattcagtta ttttgataac tttatcaaaa gacatcccac aaatgtctgt
    24541 gcgacctttg acatagtttg ctaaggtctg ttctgagatg ccagtgaact gtgctatttg
    24601 atagcgtgaa tgactattga tgaaattcat catctcttcc tttgataata cttcaatcat
    24661 agatactcct tatttgaaaa ccaaccagag tatcaatgca ataagcaatg accacaccaa
    24721 gaaggctttc cagtcaaaat catgtttgtt tactttgtat tttactttca tagcattttt
    24781 tgataatatt taagtacacc cccgaagggg tggatagtga tttctcacta tccaatttcg
    24841 aagtgccatt caagtgttag gatgataagg ttaagtttga cgaccacctt gttgttcttt
    24901 atcttgattg gcttttttaa atacctaaac atttgtactc ctttctgtta gcttccttgt
    24961 ctaaggtaac ctccccttac cttatgtaac tattatacta ttatatataa tagtattcaa
    25021 gcgattttcc taagtttttg tattttttgg ggggcaaatt aggggcaaaa actttgtaaa
    25081 aatatgtttg atattggtga ggttggtttt ttatcttttt attatccttg attttgtcgc
    25141 atttcgtaac tctttgtctc ttttagttgt tataacggat gttgtgtgct ctttttttgt
    25201 gcattttaaa tgagcaaaga acttgatgtg atgagttcgg tttatttttt attgagctct
    25261 tataagctaa taaattattg tattgatata gctagttttg tcctaaatta aaattattga
    25321 gcttctttgt tataagatta atagtaatgg aatttttaaa atcattatgt tgacctagag
    25381 tctgtgagga taa
//
LOCUS       DATTYN010000026        25319 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.26, whole genome shotgun sequence.
ACCESSION   DATTYN010000026 DATTYN010000000
VERSION     DATTYN010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25319
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.26"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            209..457
                     /locus_tag="VB649_001342"
     CDS             209..457
                     /locus_tag="VB649_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEP1670290.1"
                     /translation="MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQ
                     ALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN"
     gene            494..1105
                     /gene="amaP"
                     /locus_tag="VB649_001343"
     CDS             494..1105
                     /gene="amaP"
                     /locus_tag="VB649_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEP1670291.1"
                     /translation="MLSRKEVCMSKLLKISYCLVGLVLLSVFGWVVGITGGYIYLPYS
                     YRWLSWGMDSFPNLLDSALSYYYFWTALVLFVITFLALLVIILYPRIYTEVQLRHKNK
                     KGTLLLKKSAIESYVATAIQTAGLMPNPTVTAKLYKRKFNIIVKGRLASRVAVADQIS
                     GVKEGIEKGLTEFFGINYPVNFKVYVKDIADSDRKHITRNRVE"
     gene            1116..1304
                     /locus_tag="VB649_001344"
     CDS             1116..1304
                     /locus_tag="VB649_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEP1670292.1"
                     /translation="MEFYEKFKYPIIGGLVGLIIAILLMAFGLFKTLLAIIFIILGIY
                     GGLYAKKTGIIDQFLNRK"
     gene            1317..1856
                     /locus_tag="VB649_001345"
     CDS             1317..1856
                     /locus_tag="VB649_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP1670293.1"
                     /translation="MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLG
                     VNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVE
                     EEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKA
                     SVDNGVEKLQDQKAEPRVK"
     gene            1897..2097
                     /locus_tag="VB649_001346"
     CDS             1897..2097
                     /locus_tag="VB649_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEP1670294.1"
                     /translation="MSDEKYNAKLDQAGGKLKEGFGKISGDKSLETEGKVDKVTGKIK
                     EVIADAKDTVKGLAKGLDNKDK"
     gene            2108..2596
                     /locus_tag="VB649_001347"
     CDS             2108..2596
                     /locus_tag="VB649_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEP1670295.1"
                     /translation="MEKTQIKSTLTYDDKVIEKIVGHALENVGGLLAVTGGFFSNIKN
                     NLVNSESVTDGVSVEVGSKEVAVDLAIIVEYGKDIPAIAESIKAIVSQNVDSMTHLKV
                     VEVNVNVVDIRTKEEHEDASVTVQDRVTSAASSTSQFVSEQTEKLKDTISDTVNSDEA
                     AK"
     gene            2759..3400
                     /locus_tag="VB649_001348"
     CDS             2759..3400
                     /locus_tag="VB649_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEP1670296.1"
                     /translation="MISPKKEITSSKYQKIAISVAQRIANGEYEVGEKLKSRTTIAST
                     FNVSPETARKGLNILADLKILTLKHGSGAIVLSKERAIEFINQYESTHSIAVLKEKIR
                     ETINDQGKAMEKMAVLVNDFLMQSQSVSKQYPLAPYEIICSQDSEHFGKSIGVLNIWH
                     QTGATIVAIEHAGQFIVSPGPYSVIEKGDHIYFVGDESVISRMKTFFNLRKGL"
     gene            complement(3543..4085)
                     /locus_tag="VB649_001349"
     CDS             complement(3543..4085)
                     /locus_tag="VB649_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEP1670297.1"
                     /translation="MTKRHTETKAYVKTALTTLLTEQSFETLTVSDLTKKAGINRGTF
                     YLHYTDKFDMMNHFKNDTLDDLYRLLNQAEIYTDTRQVLNQTLSYLIEHREFITALAT
                     ISYLKFPQLIKDFCYQFLTTITGFQDIVTNQYHIPYPYALEVYLASIESIISYWIANG
                     YQETTEEVADIILKAVTLDN"
     gene            4203..4904
                     /locus_tag="VB649_001350"
     CDS             4203..4904
                     /locus_tag="VB649_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670298.1"
                     /translation="MAFIELKQVSKSYQIGETTVFANHEVSFEINKGELVVILGASGA
                     GKSTVLNILGGMDTVDAGQVIIDGKDIAHYTSKALTQYRRNAIGFVFQFYNLVPNLTA
                     KENVELAVEIVADALDPVTILKEVGLSHRLDHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILTLLQDMARTKGTTVVIVTHNAAIAPIADRVIFMHDAQVTK
                     TVINKEPASIETIDY"
     gene            4919..7555
                     /locus_tag="VB649_001351"
     CDS             4919..7555
                     /locus_tag="VB649_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEP1670299.1"
                     /translation="MIKKTLWKDILRAIKNSKGRFISLFFLMALGSFALVGLKVTGPD
                     MERTASRYLERHQVMDLTVLASHQFSQADKQELDTLKGAHLEYGHLLDVSLTSNQKSL
                     RLYSVPKKVSKPVLVKGSWPKRETDLVLSSSLAKNYQIGDELAVTSPMEGLLTTTHFQ
                     VVGFANSSEVWSKSNLGSSSTGDGSLYAYAFVNPNVFKSAFNLLRIRFSNLRLTNAFS
                     KDYQKRVTQNQAHLDNLLKDNGQKRYDDLQNQYDLALKNGRAALAKETVKLAASEENL
                     TFLEVSALQEAKHQIEQGKQALAKEEKQLEQVQATKDKLEKPSYLTYNRSTLPGGEGY
                     HTYATSTTSISNVGNIFPVVLYLVAALVAFTTMTRYVDEERTSSGLLKAIGYSNKDIS
                     LKFLIYGLLASFLGTTLGIIGGTYLLSALISEILTGALTIGKTHLYSYWFYNGIAYLL
                     AMLSAVLPAYLIVKKELFLNAAQLLLPKPPSKGAKIWLEHLTFVWKALSFTHKVTIRN
                     IFRYKQRMLMTIVGVAGSVALLFAGLGIQSSLAKVVEHQFGDLTTYDILAVGSAKATA
                     TEQTDLASYLKQEPITGYQKVSYASLTLPVKGLSDKQSISILSSSATSLSPYFNLLDS
                     QEQKKVPIPTSGVLISEKLASYYKVKPGDQLVLTDRKGQSYKVTIKQVIDMTVGHYLI
                     MSDTYFKNHFKGLEAAPAYLIKVKDKDSKHIKETASDLLTLKAIRAVSQNVNHIKSVQ
                     LVVTSLNQVMTLLVFLSILLAIVILYNLTTINIAERIRELSTIKVLGFYDQEVTLYIY
                     RETISLSLVGILLGIYLGKGLHTYIMTMISTGDIQFGVKVDAYVYLVPILVIRSLLAV
                     LGIWVNRHLKKVDMLEALKSID"
     gene            7647..8243
                     /locus_tag="VB649_001352"
     CDS             7647..8243
                     /locus_tag="VB649_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEP1670300.1"
                     /translation="MENSIEAYLADSREKVTLGTVVDCFKGKAVSSKVVPGDVGLINL
                     SDMGTLGIQYHQLRTFQMDRRQLLRYLLEDGDVLIASKGTLKKVCVFHKQNRDVVASS
                     NITVLRPQKLLRGYYIKFFLDSPIGQALLDAADHGKDVINLSTKELLDIPIPVIPLVK
                     QDYLINHYLRGLTDYHRKLNRAEQEWEYIQNEIQKGLG"
     gene            8254..9210
                     /locus_tag="VB649_001353"
     CDS             8254..9210
                     /locus_tag="VB649_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEP1670301.1"
                     /translation="MGSVERTLKMTLATIVAILIAYQLHLDYAMSAGIIALLSVLDTR
                     KSSLVVARNRLLSFFLAFGIAMMCFSLFGFTTVGFMCYLLIIIPLLYHFQIEAGLVPI
                     TVLVTHLIAKKSIALPILSNEFMLFFVGTSVALLFNAYMGPQDQQIRYYHQKVESDLK
                     GILYRFESFLLEGKGQNEGLLIKNLDKILDEALKLVYRERHNQLFQQTNYQVHYFEMR
                     RQQNRLLGQMVINVNTLMRQSKESILLSHLFHETACQLSEQNPALTLIDDIEQLLETF
                     RHGDLPQTREEFERRAVLFQLLQDLERFILLKVEFYQDYQND"
     gene            9307..10647
                     /locus_tag="VB649_001354"
     CDS             9307..10647
                     /locus_tag="VB649_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEP1670302.1"
                     /translation="MNEIKCPHCHTLFTINESEYSQLLEQVRGQAFDEELQKRLINEI
                     ALLEEKAKHQLHEVVAKKETAITSLTNQLEQIEKEQAYLRQEELAKKDQLIASLEAKL
                     DKLASQNALELANQLAEKDKEVVSLTNQLDKLALEKDATFQSKLATIEKERDGIKNQL
                     ALQAKESELSLASVRSDYEAQLKAANEQVEFYKNFKAQQSTKAIGESLELYAETEFNK
                     VRSYAFPNASFVKDNQLSSRGSKGDYIYREVDANGVEILSIMFEMKNEADTTKTKHKN
                     SDFFKELDKDRREKDCEYAVLVSMLEADNDYYNTGIVDVSHEYQKMYVVRPQLFIQLI
                     GILRNAALNSLHYKQELALIKEQNIDITHFEEDLDQFKNAFAKNYQSASNNFKKAIDE
                     IDKSIKRMEEVKRFLTTSENQLRLANNKLEDVSVKKLTRQNPTMREKFEALKDQ"
     gene            10763..11647
                     /gene="truB"
                     /locus_tag="VB649_001355"
     CDS             10763..11647
                     /gene="truB"
                     /locus_tag="VB649_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEP1670303.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMIEAGKVYEGQVTLGYSTTTEDASGEVVARSSLPAVLTEELVD
                     QTMTTFLGKITQTPPMYSAVKVNGRKLYEYARAGESVERPRREVTISLFERTSPLNFT
                     EDGLCRFSFKVACSKGTYVRTLAVDLGRALGVESHMSFLQRSASAGLTLETAYTLGEI
                     ADMVSKQEMSFLLPIEYGVADLPKMVIDDTELTEISFGRRLSLPSQEPLLAAFHGEKV
                     IAILEKRDQEYKPKKVLI"
     gene            11676..12608
                     /locus_tag="VB649_001356"
     CDS             11676..12608
                     /locus_tag="VB649_001356"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEP1670304.1"
                     /translation="MEIEYIKDYRDINQEDDTVLVLGYFDGLHRGHKALFDKAREVAN
                     KEGLKVVVFTFTESPKLAFSRFSPELLLHITYPKKRYEKFADYGVNKLYLVDFTSKFS
                     KVSSDHFITHYIKNLKAKHIVVGFDYKFGHNRTDSDYLTRNFEGQVYTIEEIKEDHRK
                     ISATWIRKLIQEGNVVKANHLLGYDLSTRGRVVHGDARGRTIGFPTANLAPIDNTYLP
                     ADGVYVTNVIVANKIYRSMTSLGKNVTFGGKELRLEVNIFDFDEEIYGEIIEIVWLDK
                     IRDMEKFEGIEDLTDRLEYDKRTALNWKKDSKLS"
     gene            12651..13055
                     /locus_tag="VB649_001357"
     CDS             12651..13055
                     /locus_tag="VB649_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEP1670305.1"
                     /translation="MVTLFLSPSCTSCRKARAWLVKHEVDFQEHNIITSPLSRDELMS
                     ILSFTENGTEDIISTRSKVFQKLDIDVEELSISDLIDLIAKNPSLLRRPIIMDQKRMQ
                     IGFNEDEIRAFLSRDYRKQELRQATIKAEIEG"
     gene            13057..13335
                     /locus_tag="VB649_001358"
     CDS             13057..13335
                     /locus_tag="VB649_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEP1670306.1"
                     /translation="MSGNYYYPLDLSWSTEEISSVLHFLNKVELAYEKKVDAKQLLDS
                     YKTYKTIVKSKAQEKQIDRDFQKVSGYSTYQVVKKAKAIEKGFFSLGN"
     gene            13325..14113
                     /locus_tag="VB649_001359"
     CDS             13325..14113
                     /locus_tag="VB649_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEP1670307.1"
                     /translation="METKYAFARQIIKEAGLFIKSKMSEQLDIQVKTQFDDLVTNVDQ
                     ETQQLLMDRIHQTYPCDAILAEENDVRHPINQGNVWVIDPIDGTVNFIVQGSQFAVMI
                     AYYEQGIGQFGLIYDVMADQLLAGGGDFEVTLNGDKLPAYQEKPLERSLIGCNAGMFA
                     RNDRNLAHLIAKTLGVRVYGGAGICMVKVMKQELLAYFSFIQPWDYAAAKVLGDKLGY
                     VLLTIDGYEPDFQTRQKIMFVPKCQLTRIASFLTKDSAVTLEDQ"
     gene            14116..15426
                     /locus_tag="VB649_001360"
     CDS             14116..15426
                     /locus_tag="VB649_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEP1670308.1"
                     /translation="MMSLPKEFINTYQAILGKELEDFLASFNQEPVNAFRINPLKNQL
                     KTFEHPIPNTLWGYYGKLSGKSPEHVSGLVYSQEPAAQMVAQVAAPQKGSRVLDLAAA
                     PGGKSTHLLAYLDNTGLLVSNEISKKRSKVLVENIERFGARNVVVTNESADRLAKVFS
                     HYFDTIVFDGPCSGEGMFRKDPDAIQYWHHGYPAECAKLQKSILEDALTMLKPGGELI
                     YSTCTWAPEENEDVVQWFLETYTFLELVDVPKLNGMVSGIGLPETARMYPHRYQGEGQ
                     FVAKLKDKRQEGQSTKLKAPKSNLTKDQLRLWKMFEKDHLNLTLSGTLQTFGDYLYLL
                     PDGLPALDGLKIARNGLELGVFKKKRFEPSYALGLALKPDEVRSSIELREEDFKPYVS
                     GNVITLPQSYPTGWYQLLINGNGLGFAKVVDKTIKNNFPKGLRF"
     gene            15565..16431
                     /locus_tag="VB649_001361"
     CDS             15565..16431
                     /locus_tag="VB649_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEP1670309.1"
                     /translation="MKMKKKFFLLSLLALSTFFLSACSSWIDKGESITAVGSTALQPL
                     VEAVADEFGSSNLGKTVNVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIANPKVKVSNLSSQQLQKIFSGEYTNWKQVGGEDLAISVINRAASSGS
                     RATFDSVIMKGVNAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLQLNGFK
                     ANAKNVATNDWPIWSYEHMYTKDKPTGLTKEFLDYMFSDEVQQNIVTHMGYISINDME
                     VVKSHDGKVTKR"
     gene            16442..17377
                     /gene="pstC"
                     /locus_tag="VB649_001362"
     CDS             16442..17377
                     /gene="pstC"
                     /locus_tag="VB649_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEP1670310.1"
                     /translation="MENQELAKKLASPSKNSRLETFGRTITFLCLALIVFIVAMILIF
                     VAQKGLSTFFVDKVNLFDFLFGKEWQPSVKNAAGIPYLGALPMITGSFLVTILSAIIA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVIVPFMRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPSSLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            17367..18254
                     /gene="pstA"
                     /locus_tag="VB649_001363"
     CDS             17367..18254
                     /gene="pstA"
                     /locus_tag="VB649_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEP1670311.1"
                     /translation="MNAKKVDKVATGTLYTIAGIIVAILASLILYILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLIVTLIISIPLSTGAGIYLAEYAKKGPVTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFYVVIPEALPGMVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NFSARFIGKKLHSKMTAAK"
     gene            18270..19073
                     /gene="pstB"
                     /locus_tag="VB649_001364"
     CDS             18270..19073
                     /gene="pstB"
                     /locus_tag="VB649_001364"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEP1670312.1"
                     /translation="MTEYNWNERHIITFPEETLALATKDLHVYYGAKEAIKGIDMQFE
                     KHKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVKDKKVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNYTIIIV
                     THNMQQAARASDYTAFFYLGNLIEYDKTRNIFQNAQCQSTNDYVSGHFG"
     gene            19086..19844
                     /gene="pstB"
                     /locus_tag="VB649_001365"
     CDS             19086..19844
                     /gene="pstB"
                     /locus_tag="VB649_001365"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEP1670313.1"
                     /translation="MTEPILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTG
                     FFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG"
     gene            19912..20565
                     /gene="phoU"
                     /locus_tag="VB649_001366"
     CDS             19912..20565
                     /gene="phoU"
                     /locus_tag="VB649_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEP1670314.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLAQINKTVRAFVSHDRELAK
                     EVIEEDDTINNFETKLEKKSLEIIALQQPVSNDLRMVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPVVEEQINLMGKAVKQMVEEALNAYINADDTKAYEIAASDEIIDQY
                     FRNIQTLAVEEIRKSPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            20770..23307
                     /locus_tag="VB649_001367"
     CDS             20770..23307
                     /locus_tag="VB649_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEP1670315.1"
                     /translation="MKTVEHLIETFVPENYNIFLDINRQTKTFTGNVAINGEALDNHV
                     AFHQKDLDIKSILLDNEAVIYQVDNDNEVVRVELPETGMMTLVIEFSGSITDNMTGIY
                     PSYYTKNGEKKEVISTQFESHFAREAFPCIDEPQAKATFDLSLTFDQEIGEIALSNMP
                     EVNIDRREETGLWTFDTTPRMSSYLLAFALGELHGKTVESKKGTTVGVYATTAHPLSS
                     LDFSLDIAVRVINFYEDYFGVHYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDE
                     NSTVQSRQQVALVIAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVSIEAIEPSWK
                     IIEDFQTGGIPLALKRDATDGVQSVHVEVNHPDEINTLFDPAIVYAKGSRLMHMLRRF
                     IGDRDFAIGLHHYFEKYQYRNTVGRDLWNILSDTSGKDVAAFMDAWLEQPGYPVLTAR
                     LENDQLILSQKQFFIGKGEEKGRLWPIPLNTNWHGLPETLTEAEMVIPNFSQLAAENE
                     VALRFNIDNTAHYITDYQGSLLDALVTELTQLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDSKSYMVAEAVQQVVSGLKRFIDEGSLAEKSFNRLVTTIYQEDFNQHGFE
                     KKADESDEDEMVRQVALGRLWLAENQTIIDGLRTIFEAYQNNIASIPAAVRRLVLANQ
                     MKYFETDSLVDIYFETYVATTDNNLRSDLTVAFSQTKQPTTIRRILVSLKDKDIIKPQ
                     DLSYWYNALLGQSFTQDIIWEWARENWDWIKSALGGDMSFDKFVIYPASNFKTPKHLA
                     EYKSFFEPKLDDMAISRNITMGINEIEARVALITKEKEAVIAALSHY"
     gene            23654..24328
                     /locus_tag="VB649_001368"
     CDS             23654..24328
                     /locus_tag="VB649_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1670316.1"
                     /translation="MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTAKEGLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
                     LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGY
                     ILKNNE"
     gene            24321..>25319
                     /locus_tag="VB649_001369"
     CDS             24321..>25319
                     /locus_tag="VB649_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1670317.1"
                     /translation="MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYS
                     SVDSSLVSVSNNASSYANRTMARISSFYFDTENNIIKALPDSDSSKLLGTPAANTDII
                     LFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
                     PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILENSEHLASSLDEVRNMRILTTNL
                     LNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQNQVNRSLRMDKALL"
BASE COUNT         8048 a         4177 c         5199 g         7895 t
ORIGIN      
        1 gtggtcactt tataaaatat tatcaaaata acattttata ggattttgaa atatcggtat
       61 tcaaacaaaa aataaactaa cactttatta tttagtttat atagtcactt tttgaaagtc
      121 gactattaaa agactattgc ttgaagaatg acagctgtta ttcttccttg gacaaaaggt
      181 acaggagtat ctaaaaagga gaattatcat gggacttatt tggactttaa tcgtcggtgc
      241 gcttattggt gtgattgctg gagcacttac taaaaaaggt ggttcaatgg gctggattgc
      301 aaacatcgct gctggtctag ttggttcttc cgttggtcaa gctttacttg gttcatgggg
      361 cccttcttta gcaggaatgt ctttgatccc gtcagttatt ggtgccgtta tcgttgttat
      421 gatcacttct tttgtactaa acaaaactaa caactagttt cctctttatt tagtaagtac
      481 ttacaaatag agaatgttaa gtagaaaaga ggtctgtatg tcaaaattgt taaagattag
      541 ttattgtctt gtcggacttg ttctattgtc tgtttttgga tgggtagttg gaataaccgg
      601 aggctatata tatttacctt atagttatcg ttggctaagt tggggtatgg atagttttcc
      661 caatctctta gattcagctt tatcctatta ttacttctgg acagcccttg tattatttgt
      721 tataacattt cttgccttat tagttattat tttataccca agaatttata ctgaggtcca
      781 gttacgccat aaaaataaaa aaggaacact tttattaaaa aaatcggcta ttgaaagtta
      841 tgttgcgacc gctattcaaa ctgcaggttt gatgccaaac ccaacagtca cagctaaatt
      901 atataagcgg aagtttaaca ttatcgttaa aggacgttta gcttctcgtg tagcagtggc
      961 agatcaaatt agtggcgtga aagaagggat cgaaaaaggt ttaaccgagt tcttcggaat
     1021 taattatcct gttaatttca aagtttatgt taaagatatt gctgattctg atcgtaaaca
     1081 tattaccaga aatcgtgtag aataggagat ctatcatgga attttatgaa aaattcaagt
     1141 accctattat tggtggcttg gtggggctaa ttattgccat attgctcatg gcttttggtt
     1201 tattcaaaac gctactagca attattttca ttattttagg aatatatggt ggcctgtatg
     1261 ccaaaaaaac aggtattatt gatcaatttc ttaatcgtaa ataaaggaga cttattatga
     1321 ctgaaactta tattaaaaac acatctaaag acttaacttc agcaattcgt ggccaattaa
     1381 catatgatga taaagtaatt gaaaaaattg ttggtttagc acttgaaaat gttgatgggt
     1441 tactgggtgt aaatggtggt ttttttgcta acctaaaaga taaattagta aacaccgaat
     1501 ctgtacgtga tggcgtgaac gtggaagttg gaaaaaaaca agttgccgtt gatcttgata
     1561 ttgtcgctga atatcaaaag catgtgccga ctatttatga ctctattaaa tcgatcgttg
     1621 aagaagaagt gaagagaatg accgatctgg atgtgattga agttaatgtt aaagtagtcg
     1681 acattaaaac aaaagaacaa tttgaagctg aaaaagtaag tttacaagac aaagtttcag
     1741 acatggcacg ttcaacatct gaatttacga gtcatcaagt tgagaatgtt aaagcttcag
     1801 tggataacgg tgttgaaaaa cttcaagatc aaaaagctga gccacgtgta aaataatcat
     1861 atgtcgtcaa ttaggtaagc taaaggaggg tttattgtgt cagatgaaaa atataatgcg
     1921 aaattagatc aagctggtgg caagttaaaa gaaggatttg gtaagatttc tggagataaa
     1981 tctttagaaa ctgaaggtaa agtagataaa gttactggaa aaattaaaga ggttattgca
     2041 gacgccaaag atactgtaaa aggattagct aaaggcttag ataataaaga taaataaagg
     2101 ggacatgatg gaaaaaactc aaattaaaag cactcttact tatgacgata aggtcatcga
     2161 aaaaattgtc ggtcatgctt tggaaaacgt tggcggatta ctagctgtaa caggtggatt
     2221 tttctcaaat atcaaaaata atttggtgaa ttctgagtct gtaactgatg gtgtttcagt
     2281 tgaagttggt agcaaggaag tagcagttga tttagcaatc attgtagaat acggtaaaga
     2341 tattcctgct attgcagaat ctattaaagc tattgtttct caaaacgttg acagtatgac
     2401 acatttgaaa gttgttgaag tcaatgtgaa cgttgttgat attcgtacta aggaagaaca
     2461 tgaagatgct agcgttactg ttcaagatcg tgtcactagt gcagcttcaa gtacttcaca
     2521 atttgtatca gaacaaacag aaaaattaaa agatactatc tctgatactg taaatagtga
     2581 tgaggcagct aaataagcaa tcgtctaggg agtattattg actagtggtg ataagtttga
     2641 gctggtattt accagctctt tttgtcacgg ttaaaaagat acggactatt gtcatctctc
     2701 taaaaatatg atttaattag atataaattt ttcaaattgt tagaaaggag taaattaagt
     2761 gataagtcct aaaaaagaga taacaagttc aaaatatcaa aaaattgcta tttcagtagc
     2821 tcagcgtatc gcaaatggcg aatatgaagt gggcgaaaag ttaaagtcaa gaactactat
     2881 cgcctcgaca tttaatgtat caccagaaac ggctcgtaaa ggcctgaata ttttagctga
     2941 cttgaaaatt ttgactttaa aacatggtag tggagctatt gtgctgtcaa aagaaagagc
     3001 tattgagttt ataaatcaat acgaatcaac ccattccatc gctgttttaa aagaaaaaat
     3061 acgtgagact attaatgatc agggaaaagc aatggaaaaa atggctgttt tggtcaatga
     3121 ttttttaatg caaagtcaat ctgttagtaa gcaataccca ttagcacctt atgagattat
     3181 ttgtagtcaa gattcggaac attttggcaa atctatcggt gtgttaaata tctggcacca
     3241 gacaggagca actatcgtcg ctattgaaca tgctggtcag tttatcgttt caccaggtcc
     3301 ttattctgtt attgaaaaag gcgatcatat ttatttcgtt ggtgatgagt cagtcatttc
     3361 acgaatgaag acctttttta atttacgaaa aggattataa gtttgagggc ccacctcaaa
     3421 ctttttttgt tgctgttgag cattattaaa agaggcagat catcatggtt tgtctttcca
     3481 aaatatctgt ttagacagtt gttttggatt gggagcatga tttcagactc ttttgatgtt
     3541 ttttaattgt ctagagtaac tgctttgaga ataatatcgg caacctcttc agtggtttct
     3601 tgatagccat tagcaatcca atagctgata atgctctcaa tactggcaag gtaaacttct
     3661 aaagcatagg gataaggaat atggtattga ttggtcacaa tgtcttggaa accagtaata
     3721 gtagtcaaaa attggtaaca gaaatccttg atgagttgcg gaaatttgag gtaagaaata
     3781 gtagcgagtg cggttataaa ttctctatgt tctataaggt aggacaaggt ttgattgagg
     3841 acttgtcgag tgtctgtgta gatttcagcc tgatttaaca aacggtacaa atcatccaga
     3901 gtgtcatttt tgaagtgatt catcatgtca aatttatcag tgtagtggag gtagaaggtt
     3961 cctctattga taccagcctt tttagtaagg tcagagacag taagagtttc aaaagattgt
     4021 tcagttagta aggtggttaa ggcggtcttt acataagctt tggtttcagt atgtcttttg
     4081 gtcattctca ggtgctcctt aaatcaacag ttgcgtcaga tttgttcttg ttaaatactt
     4141 agggccatta tataataagg ctataattaa atcaacacta tgttcaaata atggaggggc
     4201 agatggcttt tattgaatta aaacaggttt caaaatctta tcagatagga gagacgactg
     4261 tttttgccaa ccacgaagtg tcttttgaga ttaataaagg agaactagtg gttattttgg
     4321 gagcatccgg agctggtaaa tcgacagtcc tcaatatttt ggggggcatg gacacagtag
     4381 atgcaggtca agtaattatt gatggcaaag acattgctca ttacacgtct aaggccttaa
     4441 ctcagtatcg tcggaatgct attggtttcg tttttcaatt ttataatttg gttcctaatt
     4501 tgacagctaa agaaaatgtt gaattagcag ttgaaattgt agcagatgct ttagatcctg
     4561 taaccatttt aaaggaagta ggactcagtc atcgtctgga tcattttcct gctcagctct
     4621 caggtggtga acagcaacgg gtttcgatag cacgtgcctt agctaaaaac cctaaattgc
     4681 ttctttgtga tgaacctaca ggtgcccttg actaccaaac aggaaagcaa attctaaccc
     4741 tcttacagga tatggcacga actaagggga ccacggtagt tattgtaacc cacaatgctg
     4801 ctattgctcc gatagctgat cgtgtcattt ttatgcatga tgcacaggtt accaagacag
     4861 tcattaataa ggaacctgca agcattgaga caattgatta ttaagaggaa ggtgtcgtat
     4921 gataaagaaa accttatgga aggatatttt gagagctatc aagaatagta aagggcgatt
     4981 catttcctta tttttcctaa tggccttagg ctcctttgct ttagttggac ttaaagtcac
     5041 cggtccagat atggaacgaa cagccagccg ttacctcgaa agacaccagg tgatggacct
     5101 aacggtactg gcttctcatc aattttccca agccgataaa caagagttag atacgttaaa
     5161 aggggctcat ttagaatatg gtcatttact tgatgtcagt ctaactagca accagaaatc
     5221 tcttaggctc tatagcgtgc caaagaaagt gtctaagcca gtcttggtta aagggagttg
     5281 gccaaagcga gagacagatt tggttttatc ctcctcactt gctaaaaact atcagattgg
     5341 agatgaacta gcagtcacct cacctatgga aggtttgctg acgacaaccc attttcaagt
     5401 ggttggtttt gcgaattctt cagaagtttg gtccaagtcc aatttaggaa gttcctcaac
     5461 cggagatgga agtctctacg cttatgcttt tgttaatcca aacgttttta aaagtgcctt
     5521 taacctgctg cgcatccgtt ttagtaatct tcgtctgaca aacgcttttt ccaaagacta
     5581 tcaaaaaagg gtaacccaaa accaagctca tttggataat ctacttaaag ataatggcca
     5641 gaagcgttat gatgacctcc aaaatcagta tgaccttgcc ttaaaaaatg gcagagcagc
     5701 acttgcaaag gaaacagtga aactagctgc gagtgaggag aacttaactt ttttagaagt
     5761 ctctgcttta caagaagcta agcatcagat tgaacaaggc aaacaagcat tagccaagga
     5821 ggaaaagcag ttagagcagg tgcaggctac aaaagataag ctagaaaaac ccagttacct
     5881 gacttataat cgctcgaccc taccaggagg agaaggatat catacttatg caacttcaac
     5941 gacctccatt tcaaatgttg gaaatatttt tcctgttgtt ctttatctcg tagctgctct
     6001 agtagccttt accaccatga cacgttatgt tgatgaagaa agaacaagct ctggtctatt
     6061 aaaagccatt ggttattcta acaaggatat cagtttaaag tttcttatct atgggctttt
     6121 agccagtttt ttagggacaa ctttaggtat tattggggga acttacctct tatctgcctt
     6181 gatttcagag atcttaacag gagctttgac tattggaaag actcaccttt atagttattg
     6241 gttttataat ggcatagctt acttgctggc tatgttatct gctgttttac cagcctactt
     6301 aattgtcaaa aaggaattat tcctcaatgc agctcagtta ttgctgccca aacctcctag
     6361 taagggggca aaaatctggt tggaacacct tacttttgtc tggaaagccc tgtcctttac
     6421 tcacaaggtg accatacgta atatttttcg ctataaacaa agaatgctga tgaccattgt
     6481 aggcgttgca ggctcagtag cccttttatt tgcaggctta gggattcagt cgtcattagc
     6541 caaagtagtt gagcatcaat ttggtgattt aacgacttat gatattttgg ctgtcggttc
     6601 ggccaaagcg acagcgacag agcaaactga cttagctagc tatcttaaac aagaacctat
     6661 tacagggtac caaaaggtat cttatgccag cttaactctt cctgtaaagg gattatctga
     6721 taagcaaagt atttccattt tatcaagttc agctacttct cttagcccct attttaatct
     6781 gctggatagt caggagcaaa agaaggttcc cattccaacc tctggtgttt tgatttctga
     6841 gaaattagcc tcctattaca aggtaaaacc aggtgatcag ttggtattga ctgatcggaa
     6901 aggacagtct tataaagtga cgattaaaca ggttattgac atgacagttg gccattacct
     6961 gataatgtct gatacctatt ttaagaatca ttttaaagga ttggaggctg ctcctgccta
     7021 tctgattaag gtaaaagaca aagatagcaa gcacataaag gagacagcca gtgacttgtt
     7081 aaccttaaaa gcgattagag cagtttcaca aaacgtcaat catattaaat ctgttcagct
     7141 agtagtcacc tctcttaatc aggtcatgac cctccttgtc ttcttgtcta ttttattagc
     7201 aatcgttatc ctttataact taacgactat taatattgct gagcgtattc gagaattatc
     7261 cactattaaa gttctgggat tttacgatca ggaggtcacc ttatatattt atcgagaaac
     7321 tatttcgcta tccctagtag gcattctttt aggtatctat ttaggaaaag gcctgcatac
     7381 ttatatcatg acaatgattt caactgggga tattcaattt ggtgtaaagg ttgatgctta
     7441 tgtttatcta gtgccaattc tagtaatccg tagcttgtta gcggtattag gtatctgggt
     7501 taatcgccat ttaaaaaagg ttgatatgtt agaagctttg aaatccatag attgattggt
     7561 gaaaagacag atatagacag cacttgaaaa gttaatcata ttatgatagt atctaaatac
     7621 tataattcaa tagaaagata ctatgtatgg aaaatagcat tgaggcctat ctagcagata
     7681 gcagagaaaa ggtaacatta ggtacagttg ttgattgttt taaaggaaaa gcagtctcaa
     7741 gtaaggttgt gccaggtgat gtgggattga ttaatttatc tgacatgggc accttaggga
     7801 ttcaatatca ccaattaaga actttccaga tggatcgtag gcagctcttg cgttaccttt
     7861 tggaagacgg agatgtctta atcgcctcta agggaaccct aaaaaaagtc tgtgtttttc
     7921 ataagcaaaa tcgagatgtg gtggcatcat caaatatcac tgtcttacgc cctcaaaaac
     7981 tgttaagggg ctactatatc aagttctttt tggactcacc tattggtcaa gcgctcttgg
     8041 atgcagcgga ccatggcaaa gatgtgatca atctctcaac gaaagaattg ttggatattc
     8101 caattcccgt tattccttta gtgaaacagg actatttgat taatcactac ttgagaggat
     8161 taacagatta tcatcgtaaa ctcaatcgag cagaacaaga gtgggaatat attcagaatg
     8221 aaattcaaaa aggattaggt taggagtctt gtcatgggtt cagttgaacg tacattaaaa
     8281 atgaccttgg ctaccattgt tgccatttta attgcttacc aacttcatct ggattatgca
     8341 atgtcagcgg ggattattgc cctgttaagt gttttagaca cccgtaagtc cagtttggtg
     8401 gtcgctagga atcgcttgct atcttttttt ctggctttcg ggattgcgat gatgtgcttt
     8461 agcttgtttg gttttacgac agtaggtttt atgtgttatt tgttaattat tattcctttg
     8521 ctctatcact ttcagataga ggcaggactg gttcctataa cagtacttgt gacacatttg
     8581 attgctaaaa aaagtattgc attacctatt ttatcgaatg agtttatgct cttttttgta
     8641 gggactagtg tcgctttact atttaatgct tatatgggtc cacaagatca gcaaattcgg
     8701 tactatcacc aaaaagttga atcggatctg aaaggtatct tataccgttt tgaaagtttt
     8761 ctactggaag gaaaaggtca aaatgaaggg ctcttgatca aaaaccttga taaaatatta
     8821 gatgaagctc taaaactagt ttatcgagaa aggcataatc aactatttca gcagaccaat
     8881 tatcaagttc attattttga gatgcgacga caacaaaata gactattggg acaaatggtt
     8941 atcaacgtaa acacgttaat gagacaaagt aaggaaagta ttcttttgtc acatcttttt
     9001 cacgaaactg cttgtcagct aagcgaacaa aatccggctt taaccttgat tgatgacatc
     9061 gaacaattgc ttgaaacctt tcgtcatggt gatcttcctc aaactcggga ggaatttgag
     9121 cgacgtgcgg ttttatttca gctcttacaa gacttggaac gttttatctt attaaaggta
     9181 gagttttatc aggattatca aaatgactaa atctctattg cacacttctt atctatgaca
     9241 gcttgggact taacttcctg agcttttttg ctataataaa aacaagaatc tcagaatgga
     9301 gacaagatga acgaaataaa atgccctcat tgtcataccc tatttactat caatgagtca
     9361 gagtatagtc aattattgga acaagtcaga gggcaagcct ttgatgaaga attgcaaaaa
     9421 cggttaatca atgagatagc cttgctggaa gaaaaagcga agcatcaatt gcatgaggtt
     9481 gtcgcaaaaa aagaaacagc tattaccagc ttgacaaacc aattagagca aattgaaaaa
     9541 gaacaagcct acctcagaca agaagaactg gctaaaaaag accagcttat tgcttcttta
     9601 gaagcgaaac ttgataaatt agcctcgcaa aatgctttgg aactggccaa tcaattagct
     9661 gagaaggaca aagaagtggt tagtttgacc aatcagctgg acaaattagc acttgaaaaa
     9721 gatgccacgt tccagtcaaa acttgctaca atcgaaaaag aacgcgatgg aatcaaaaac
     9781 caattggcgc ttcaagctaa agaaagtgaa ttgtcgttgg cttcggtgcg cagcgactac
     9841 gaagcacagt taaaagcggc taacgagcaa gttgaatttt ataaaaattt caaagcgcag
     9901 caatctacca aagcaatcgg agagagtcta gaactctatg ctgaaacaga gtttaacaaa
     9961 gtaagaagct atgctttccc caatgctagc tttgtcaaag ataaccaatt gtctagtcgt
    10021 gggtcaaaag gggactatat ttaccgagag gttgatgcca atggtgtaga aatcctctct
    10081 atcatgtttg agatgaagaa cgaggcagac accaccaaaa caaaacataa aaatagtgat
    10141 tttttcaagg agttagataa agaccgtcgc gaaaaagatt gtgagtatgc tgttttggta
    10201 agcatgttag aagctgataa tgattactac aatacaggga ttgttgatgt cagtcatgag
    10261 tatcaaaaga tgtatgtggt tcgtcctcaa ctctttattc agttgatagg gattctgcga
    10321 aatgcagccc tgaatagttt acattataag caagagttgg ccttgattaa ggaacaaaat
    10381 attgacatca ctcacttcga agaggatttg gatcaattta agaatgcctt tgctaagaac
    10441 tatcagtctg ccagcaacaa ctttaaaaag gctattgacg agattgataa atcgattaaa
    10501 cgcatggagg aagtgaaacg ctttttaacc actagtgaaa atcagttacg cttagctaat
    10561 aataaattag aggatgtttc agttaaaaaa ctgacccgcc aaaacccaac catgcgagag
    10621 aaatttgaag ccctcaagga ccagtaagcc tgaaagtgag tctttccctg ctaaaattgg
    10681 ttaagcgttt attttggcaa aactgatgat aaagcggtag aatagaatca gtaataatta
    10741 ctaattagag agaaaaatag acatgataaa tggaatcatt aatttaaaaa aagaagccgg
    10801 catgacctct catgacgcag tttttaaatt acggaagtta ttacaagaaa aaaagattgg
    10861 acatgggggg accttagatc ctgatgtggt cggtgttcta ccaattgcag ttggtaaggc
    10921 tactcgtgtg atcgaataca tgatagaagc tggtaaagtt tatgaagggc aagtgactct
    10981 cggttactca acaacgactg aggatgctag tggagaggta gttgcgaggt cctctttgcc
    11041 agctgtgcta acagaagaac tcgttgatca aacgatgacg actttccttg ggaaaatcac
    11101 acagacccca cctatgtatt cagccgtaaa ggttaatggc cgtaaattgt acgagtatgc
    11161 gcgtgctggt gaaagtgtgg aacgtcctag aagagaagtg actatttctc tgtttgaacg
    11221 caccagccct ttgaatttta ctgaagacgg tctttgccga ttctctttta aagttgcttg
    11281 tagcaagggg acttatgtgc ggaccttagc agttgattta ggtcgagctc taggggtaga
    11341 gagtcatatg tccttcttgc agcgatcagc ttcagcagga ttaaccctcg agactgccta
    11401 tactttggga gaaattgctg atatggtttc taaacaagag atgtcttttt tgttaccgat
    11461 cgagtatggc gttgctgatc ttcctaaaat ggttattgat gatactgaat tgactgaaat
    11521 ttcatttggt cgccgtctta gtctccctag tcaagagcca ctgttagctg cttttcatgg
    11581 cgaaaaagta attgctattt tagaaaaaag agatcaagaa tacaaaccca aaaaagttct
    11641 tatttaaata gtttgagtaa gtagaatgga taattatgga aattgaatat atcaaagatt
    11701 atcgtgatat taaccaagaa gatgatacag tcttggtatt gggatatttt gatggattac
    11761 accgtggtca taaagcctta tttgacaaag caagagaggt tgcaaataaa gaagggttaa
    11821 aagtagtcgt ttttacgttt acagagtctc cgaaattggc tttttcgcgt ttttctcctg
    11881 agttattgct tcatattact tatccaaaga agcgttatga aaaatttgcc gattacggtg
    11941 taaataaatt atatttggtt gattttactt ctaaattctc taaggtctca tctgatcatt
    12001 ttataactca ttatattaaa aacctgaaag caaagcatat tgttgtcggt tttgactata
    12061 agtttgggca taatcgtaca gatagtgatt atttaaccag aaattttgaa ggacaagttt
    12121 ataccattga ggaaataaaa gaagatcatc gaaaaatttc tgctacatgg ataaggaagc
    12181 ttattcaaga aggtaatgta gttaaagcaa accacttgtt aggctatgac ttatcgacaa
    12241 gggggagagt cgttcacggg gatgcgcgtg gccgtactat tggtttccca acagccaatt
    12301 tagctccaat tgacaacaca tacttaccag ctgatggagt ctatgttaca aatgttattg
    12361 ttgctaataa aatctatcgc tctatgacga gtttaggtaa aaatgtgaca tttgggggga
    12421 aagagttgcg tctagaagtt aacatttttg actttgacga agagatctat ggagaaatta
    12481 ttgagattgt ttggttagat aagattcgag acatggaaaa attcgaggga atcgaagatt
    12541 tgactgatag attggaatat gataaacgaa cagcattaaa ttggaaaaaa gatagcaaat
    12601 tatcttaaat ttttgtataa taaggtaagt aaatttgata gaggaaaaat atggttacct
    12661 tatttttatc acctagctgt accagttgtc ggaaagcaag ggcatggtta gtaaaacacg
    12721 aagttgactt tcaagagcat aatattatta caagtccatt aagccgtgat gaattaatgt
    12781 caatcctctc ttttacagag aatggaacgg aggatattat ttcaacacgt tcaaaggttt
    12841 ttcaaaaact tgatattgat gtagaagagc tttctatttc agatttaatt gatttaattg
    12901 ctaaaaatcc aagtcttctt cgtcgcccta ttatcatgga tcaaaaacgc atgcaaattg
    12961 gttttaatga agatgaaatt agagcgtttt tatcgagaga ttatcgcaag caagaactac
    13021 gtcaagcaac gataaaagca gaaattgagg ggtgatatgt caggtaatta ttattatcca
    13081 cttgacttaa gttggagcac tgaagaaata tcctcagtgc ttcatttttt gaataaagtg
    13141 gagttagcat atgaaaaaaa agtagatgca aaacaactcc tagatagtta taagacttat
    13201 aaaaccattg tcaaaagtaa agctcaggaa aagcaaatcg accgtgattt tcaaaaagtt
    13261 agtggttatt cgacctatca agttgttaaa aaagcgaagg caattgagaa aggattcttt
    13321 tcccttggaa actaaatacg catttgcaag gcaaatcatt aaagaagcag ggctttttat
    13381 caagtcaaaa atgtcagagc agctagatat tcaggtgaaa acacaatttg atgatctggt
    13441 taccaatgtt gatcaagaaa ctcaacagtt actgatggat cgtattcatc agacctatcc
    13501 ttgtgatgcc attttagctg aagaaaatga cgttcgtcac cccattaatc aaggaaatgt
    13561 ttgggtcatc gatcccattg atggaacggt taactttatt gtgcagggat cacagtttgc
    13621 agtgatgatt gcctattatg aacaaggaat tggccaattt gggcttattt atgatgtgat
    13681 ggcagatcaa ttactagctg gtggtggtga ttttgaagtt actttaaacg gtgataagct
    13741 tccagcttac caagaaaaac ctttagagcg tagcttaatt ggctgcaatg caggcatgtt
    13801 tgccagaaat gatcgtaacc ttgctcatct aattgcaaag actttaggtg taagggttta
    13861 tggtggtgca ggtatctgca tggttaaggt catgaagcag gaattactgg cctatttttc
    13921 atttatccaa ccatgggatt acgcagcagc aaaagtacta ggcgataaac tgggttatgt
    13981 tttactaact attgacggat atgaacctga ttttcaaaca cgtcaaaaaa tcatgtttgt
    14041 tcctaaatgc caactcacta ggatagcgtc ttttctaaca aaggactctg ccgtcacact
    14101 tgaagatcaa tagaaatgat gtcattacca aaagaattta ttaacactta tcaagcaata
    14161 ctaggcaaag aattagaaga tttcttggca agttttaacc aagaaccggt caatgctttt
    14221 cggattaacc ccttaaagaa tcaactaaaa acctttgaac accccattcc aaatacctta
    14281 tggggatatt atggtaaact atctggcaag tctccagagc atgtgtcggg gttggtttat
    14341 tcccaagaac cagcggctca aatggtggca caagtagcgg ctcctcaaaa ggggagtcgt
    14401 gttttagact tggcagctgc accaggagga aaatcaactc atttattagc ttatttagac
    14461 aatacaggtc ttttagtcag caatgaaatt tctaagaagc gcagcaaggt tttagttgaa
    14521 aatatcgaac gttttggcgc tagaaatgtt gtggtgacta atgaatccgc agatcgttta
    14581 gccaaggtat tttctcatta ttttgatact atcgtctttg atggaccatg ttctggtgaa
    14641 ggaatgtttc gcaaggaccc tgatgctatt caatattggc atcacgggta tcccgcagaa
    14701 tgcgccaagt tgcaaaaatc tattttagaa gacgccttaa ccatgttaaa accaggagga
    14761 gaattgatat actccacctg tacttgggct cctgaagaaa atgaagatgt tgtgcagtgg
    14821 ttcttagaga cttatacctt tttagaattg gttgatgttc caaaactaaa tggaatggtt
    14881 agtggtatcg gacttccaga gactgctaga atgtaccctc atcgttatca aggggaaggg
    14941 caatttgtgg ccaagctaaa agataagcgt caagaaggac aaagcactaa actaaaagca
    15001 cctaaatcca atttgaccaa agaccagtta cgtctttgga aaatgtttga aaaagaccat
    15061 ctaaacctta ccctatcagg aacactacaa acctttggtg attacctata cctcttgcca
    15121 gatggtcttc ctgctttaga tggccttaaa attgctcgga acggtttaga attaggcgtc
    15181 ttcaagaaga aacgctttga accctcttac gccttgggat tagctttaaa gcctgatgag
    15241 gtccgatcat ctattgagct tagagaggaa gactttaaac cttatgtgtc aggtaacgtc
    15301 attactttgc cccaatctta tccaacaggc tggtaccaat tactcattaa tggcaatggt
    15361 ctaggatttg ccaaggtcgt tgacaagacc atcaaaaata atttccctaa agggttaaga
    15421 ttttagcgta aaaaataaga ttaaaaagtt aaatatttaa agaaaaaatg ctttcaaagc
    15481 ataggtagat atgttactat aaagaatatg tggcacttag tttctacata tatacccttt
    15541 atttttacga ataggaaata aataatgaaa atgaaaaaaa aattcttttt gttaagtctt
    15601 ttggccctat caactttctt tttatccgca tgttctagct ggattgataa aggtgagtca
    15661 ataaccgctg taggatcaac agcactacaa cccttagtag aagcagtagc tgatgaattt
    15721 ggaagcagta acctaggcaa gactgtcaat gttcaaggtg gtggttcagg tacagggttg
    15781 tctcaagttc aatcaggagc tgtccaaatt ggaaatagtg atgtctttgc ggaagaaaaa
    15841 gatggtattg atgcttctaa attagttgat catcaagtag ctgttgcagg acttgcagtt
    15901 attgccaatc ctaaagtcaa ggtttccaat ctcagtagtc agcagttgca aaagattttt
    15961 tcaggagaat ataccaattg gaaacaagtt ggaggagaag atcttgcgat ttcagtgatc
    16021 aaccgagcag caagttctgg ctcacgagca acctttgaca gtgttatcat gaaaggggtc
    16081 aacgctaaac aaagtcaaga gcaagactcc aatgggatgg ttaaatcgat tgtttcacaa
    16141 acaccaggtg ccatttctta cctttccttt gcctacgttg attcatctgt taaatctttg
    16201 caattaaatg ggtttaaggc aaatgctaag aacgtggcta caaatgattg gccaatctgg
    16261 tcctacgaac acatgtatac caaagataaa ccaacagggt tgaccaagga atttcttgat
    16321 tatatgtttt cagatgaagt acaacagaac attgttacac atatgggata tatttcgata
    16381 aatgatatgg aagtggtcaa atctcatgat ggaaaagtaa caaaaaggta atggaggaat
    16441 tatggaaaat caggaattgg ctaaaaaatt agcctcacca tcaaagaatt caagacttga
    16501 aacctttggc cgcaccatta cgtttttgtg tctggctttg attgttttta tcgttgcgat
    16561 gattctgatc ttcgttgctc aaaaagggtt gtcaaccttc tttgttgaca aggttaatct
    16621 ttttgatttc ttgtttggaa aggagtggca accaagtgtg aaaaatgcgg ccggcattcc
    16681 ttatcttggt gctctgccaa tgattacagg atcctttttg gttaccattt tatctgctat
    16741 tattgccacc ccatttgcca ttggcgcagc cgtttttatg actgaaatct cacctaaata
    16801 tggtgctaaa ttattacagc ctgcggttga gcttttggtt ggaattcctt cggttgttta
    16861 tgggtttatc ggtttgcaag tgattgttcc ttttatgcgc tctatctttg gtggcacagg
    16921 ttttggaatc ctatctgggg tctgtgtctt gtttgttatg attttaccaa cagtgacttt
    16981 tatgacaaca gacagtctgc gggcggtgcc tcgtcattac cgcgaagcgt ctatggctat
    17041 gggagcaaca cgttggcaaa ccatttggcg tgttgtcctt aatgcagctc gtccaggaat
    17101 ttttaccgct gttatttttg gaatggcgag agcttttgga gaagccttgg ctatccaaat
    17161 ggtagtcggt aactctgctg taatgccaag ttcactaacg acaccagccg caaccttaac
    17221 gtctgtcttg acaatgggta ttggtaacac ggttatggga acggtccaaa ataatgtgct
    17281 ttggtccctt gccctagtct tattattaat gagtctggcc ttcaattccc ttgtcaaatt
    17341 aatcacgaaa gaaagaaaga gaaattatga acgctaaaaa agtcgataaa gtagcaactg
    17401 gtactcttta taccattgct ggaattattg tagctatttt agcttcctta attctatata
    17461 tccttgtccg tggcttgcca cacatcagct ggtccttttt aacaggaaaa tcgtcttcgt
    17521 acgaagctgg tgggggaatt ggtatccagt tgtataattc cttcttccta ttgattgtta
    17581 ctttaattat ttccattcct ttatcaactg gagcggggat ttacttggct gaatatgcca
    17641 aaaaagggcc tgttaccaac tttattagaa cctgtattga gattctgtct tccctaccat
    17701 ctgtggttgt ggggctcttt ggttacttga ttttcgttgt gcagtttgaa tatggctttt
    17761 ctattatttc aggggctctt gctttgacgg tctttaatct tcctcaaatg acccgtaatg
    17821 ttgaagatag tttactgcat gttcatcata cccaaagaga agcaggatta gctttaggcc
    17881 tgtcacgctg ggaaacggtt ttttatgtgg ttatcccaga agctctcccg ggaatggtaa
    17941 caggtattgt cttagcttca ggtcgtattt ttggtgaagc ggcagcgctt atctatactg
    18001 ctggtcaatc agcaccagct ctggattggt caaattggaa tccacttagt gttactagtc
    18061 caatctctat tttccgtcaa tctgagaccc ttgctgttca tatttggaaa gtcaatagcg
    18121 aagggacaat tccagatgct actcttgtat ccgcaggaag tgcagcagtg ctattaattt
    18181 ttatccttat tttcaacttt tcagctcgct ttattgggaa gaaacttcat tctaaaatga
    18241 cagcagcgaa ataagatatt ggagaaatca tgacagaata caattggaat gaacgtcata
    18301 tcatcacttt tcctgaagaa acgcttgctc tagctaccaa ggatttacat gtttactatg
    18361 gtgcgaaaga agctatcaaa gggattgata tgcagtttga aaaacataaa ataacagcct
    18421 tgattggtcc atctggttgt ggcaaatcaa cttatcttcg tagtcttaac cgcatgaacg
    18481 ataccattga tattgctcgg gttacaggtg agattcttta tcagggcatt gatgttaatc
    18541 gaaaagacat gaatgtttac gagattcgca agcacttagg aatggttttt caaagaccca
    18601 atcctttcgc taaatccatt tataaaaaca ttacctttgc ccatgaaaga gctggtgtga
    18661 aagacaaaaa agttttagat gaaattgttg agacttcact gaaacaagcc gcgctttggg
    18721 atcaagttaa agatgacctt cacaaatcag ccttcacctt atcagggggt cagcaacaac
    18781 gcttgtgtat tgctagagcc atttctgtca aacctgatat tctattaatg gatgaaccag
    18841 cctctgccct tgacccgatt gcaacgatgc agctggaaga aaccatgttt gaattgaaga
    18901 agaattacac gattattatt gtgacccaca atatgcaaca agcagctcgt gccagtgatt
    18961 acactgcctt cttctattta ggcaacctca ttgaatatga taagacacgt aatattttcc
    19021 aaaatgcgca atgtcagtca acaaacgact acgtttcagg gcactttggt tagaaaggta
    19081 atatgatgac agaacctatt ttacagatca gagacctttc tgtttactac aatcaaaaga
    19141 aaacgttaaa agatgtctct ttggaccttt atccaaatga aataacagct ttaattggtc
    19201 cttctggatc tgggaaatca acgctcttgc gttctatcaa ccgtatgaat gatttgaatc
    19261 ctgaagtaac cattacaggc tctatcgtct ataacggaca caatatttat agtccaagga
    19321 cagatacggt tgatttacgc aaagaaattg gtatggtatt ccaacaaccc aacccatttc
    19381 cgatgtctat ttatgagaac gtggtttacg gccttcgctt aaaaggtatc agagataaat
    19441 caatcttaga ccatgctgtt gaaagctctc ttaaaggggc ttccatttgg aatgaagtca
    19501 aagatcgttt acatgattct gcggttggct tatcaggcgg acagcaacag agagtttgca
    19561 tagctagagt tcttgctacc agccccagaa taatcctttt agatgaacct acctcagctc
    19621 ttgatcctat ctcagctggg aaaattgaag aaacattatt gttattaaaa aaagattata
    19681 cactggctat tgtgacccgc tcaatgcagc aagcctcacg tttatcagat cgaacaggtt
    19741 ttttcttgga gggtgactta cttgagtgtg gtcctacaaa agccatgttt atgaatccta
    19801 agcgcaaaga aaccgaagac tatatttctg gtaaatttgg ttgagaaaga cgtatatggt
    19861 tgacccctct gtgtttttat tataatgact agattgtagg aagaaaaaat catgttaaga
    19921 acgaaatttg aagaagaatt agataaattg cataaccagt tttattcaat gggaacggaa
    19981 gtattggcac aaatcaataa aactgttcgt gcctttgtta gtcatgatcg tgaattggcc
    20041 aaagaagtta tcgaagaaga tgacactatt aataattttg agacaaagct tgaaaagaaa
    20101 tcgctggaaa ttattgccct acaacagcca gtttcgaatg atcttagaat ggttattact
    20161 gttttaaagg catcaagtga tattgaacgc atgggtgacc atgctgcttc gattgccaag
    20221 gccactattc gtatgaaagg agaggagcgt attccagtgg ttgaagaaca aatcaacctt
    20281 atgggaaaag ctgtgaaaca gatggtagaa gaagccctta atgcatatat caatgctgac
    20341 gatacaaaag cttatgaaat cgcagcttct gatgagatta tcgatcaata tttccgtaat
    20401 atccaaacct tagctgttga agaaatccgt aagtctccag atgctgtttt tgcaggaaaa
    20461 gaatattttc aagtattaat gtatttggaa cgtattggtg actatgctcg caacatttgt
    20521 gaatggattg tttatcttaa aactggaaaa attattgaat tataagaaat tatgctataa
    20581 tgagactggg aaacagcttg ccagtccctg gttttatacg aaattgtgca agttagaaaa
    20641 tgaactaaca agaaaagttt tctttgctga atctgatttt gttaggttaa caaatatatg
    20701 tagacagaga tgatacttag gtatcatctg ttgatctatt atgatttgtt attagaatta
    20761 aggagttata tgaagacagt agaacatctc atcgaaacat ttgtgcctga aaattataac
    20821 atctttttag atattaatcg tcagactaaa acatttacgg ggaatgttgc gattaatggt
    20881 gaagctttag ataatcatgt ggctttccac caaaaagatt tggacattaa gtctattttg
    20941 ctcgataatg aagctgttat ttatcaagtg gataacgaca atgaagttgt gcgtgttgaa
    21001 ttacctgaaa caggaatgat gacgcttgtc attgaatttt caggtagcat tacagataat
    21061 atgacaggta tttacccttc atattacact aaaaatggtg agaaaaaaga agtcatttca
    21121 actcagtttg aaagccattt tgcacgtgaa gctttcccat gtatcgatga accacaagca
    21181 aaagctactt ttgatttaag cttgaccttt gatcaagaaa ttggtgagat agcgttatcg
    21241 aatatgccag aagtcaatat tgaccgtcgc gaggagactg gtctttggac atttgatacg
    21301 acaccaagaa tgtcatctta cttgctagcg tttgcgctag gagaacttca tggaaagact
    21361 gtagaaagca aaaaaggaac aactgttggt gtgtatgcga caacagcgca tcctcttagc
    21421 tcgcttgatt tttcattgga tattgcagtt cgtgttatca acttttatga agactatttt
    21481 ggagtacatt acccaatccc gcaatctctt aatattgcgc ttccagattt ttcatctggt
    21541 gctatggaaa attggggttt aatcacttat cgtgaaattt atttattagt agatgaaaat
    21601 tcgactgttc aaagccgaca acaagttgca cttgtaatcg cccacgagat agcacaccaa
    21661 tggtttggaa acttggttac aatgaaatgg tgggacgatc tgtggttaaa tgagagtttt
    21721 gccaacatga tggaatatgt ctctatcgag gctattgagc cgtcttggaa aataatagaa
    21781 gatttccaaa caggcggtat tcctcttgct ttaaaacgtg atgctactga tggtgttcaa
    21841 tcagtgcatg ttgaagtcaa tcatccagat gagataaata cattgtttga tcctgctatt
    21901 gtctatgcaa aaggtagtcg tttgatgcat atgttacgcc gttttattgg tgatcgtgat
    21961 tttgccattg gcttacatca ctactttgaa aaatatcaat atcgaaatac tgtcgggcgt
    22021 gatttatgga atattttatc agatacttca ggcaaagacg tagctgcttt tatggatgct
    22081 tggcttgaac aaccaggtta tccagtttta acagctcgcc ttgaaaacga tcaattgatt
    22141 ttgagtcaaa aacaattttt tattggaaaa ggtgaagaaa aaggtcgcct ttggccgatt
    22201 cctttaaaca ctaattggca tggccttcct gaaactttga cagaggcaga aatggtcatt
    22261 ccaaacttta gtcaattggc agcagaaaat gaagtagctc tacgtttcaa tattgataat
    22321 acagctcatt acattacaga ctaccaagga tcattattag atgccttagt cactgaactt
    22381 acccaacttg ataatacttc tgctttacaa gttattcaag aacgtcgttt attggcagat
    22441 agtggcttga tttcctatgc tgaattggtt gacttaattg ctcaattgga cgattctaag
    22501 tcttatatgg tagcagaagc ggttcagcaa gtggtctctg gtttgaaacg cttcattgat
    22561 gaaggaagct tagcagaaaa atcctttaat cgcttggtaa ccaccatcta tcaagaagac
    22621 tttaatcagc atggttttga gaaaaaagct gacgaatcag atgaagatga gatggtacgt
    22681 caggttgcct tgggccgctt gtggctagca gaaaatcaga cgattattga cggattgaga
    22741 actatttttg aagcatatca aaacaatatt gcaagtattc cagcagctgt tcgtcgcttg
    22801 gttttagcca accaaatgaa atattttgaa acagatagct tggttgatat ttattttgag
    22861 acttatgtag caactactga taataattta cgcagtgatt taacggttgc ttttagtcaa
    22921 acaaaacaac caactactat tagacgtatt cttgttagtt taaaagataa agatattatt
    22981 aaacctcagg atttatctta ttggtacaat gctttgcttg gacaaagctt tactcaagat
    23041 atcatttggg aatgggctag agaaaattgg gattggatta aatctgcact tggtggagat
    23101 atgagctttg ataaatttgt tatttatcca gcaagtaact ttaaaacacc aaaacatcta
    23161 gcagaatata aatctttctt tgaacctaag ctagatgata tggctattag ccgtaatatt
    23221 accatgggaa ttaatgaaat tgaagcacgt gttgctttga tcactaaaga aaaagaagca
    23281 gttattgcag ctctcagtca ttactagacc ataagcaaaa gagttggggg gactttccag
    23341 ctcttttttg tagtgagcta gcttcctttc ttagttccgt ctataactaa atgattatcc
    23401 atagtttaat tcaaaaggag attgcacttt aaagcgaagg ctattagcct cttaaatact
    23461 tttttaccag gtggtgaata agaacaatta taaatgattt aatcattatg ctttaaatgc
    23521 cttaaaggag tattaatatt ttagtaaacc ttaagctttt tgtagtatag tctcgttaga
    23581 aattgttatc agaaatgaga ctaagttaaa tgaagtgata gttactttat ttaagaacaa
    23641 ttgaggtaga gacatgataa aaatattatt agtagaagat gacttgagct tatcaaattc
    23701 catttttgat tttttagatg attttgcaga cgtcatgcaa gtttttgatg gcgatgaagg
    23761 tttatacgaa gcagaaagtg gtatttatga tttgattttg ttagacctta tgttgccgga
    23821 gaaaaatggc tttcaagtct taaaagaatt gcgagaaaaa gatattaaaa ttcctgtgtt
    23881 gatcatgaca gctaaagagg gtttagatga taaaggtcac ggatttgaat taggtgctga
    23941 tgattatctg accaagccgt tctatttaga agagttaaaa atgcgaattc aagcactgtt
    24001 aaaaagaaca gggaaatttg cagataaaaa tattagtttt ggcaatttag tggttgactt
    24061 agctcgaaaa gaggtgaagg ttgaagggaa agtagttgaa ttacttggca aagaatttga
    24121 tttgttggtg tatcttttgc aaaatcaaaa cgttatttta ccaaagacac aaatttttga
    24181 tcgtttatgg ggattcgata gtgatactac gatttcggtt gttgaagttt acatttctaa
    24241 aataaggaaa aaattaaaag gtacccgttt tgttaacagg cttcaaactt taagaagcgt
    24301 agggtatatt ctaaaaaaca atgaataaat taaaaaaaga gattttatca gataactata
    24361 accacttttt tcattttttt gcggttttta caggtatttt tgtcattatg actattatta
    24421 tcttacagat tatgcggttt ggcgtttatt cgtcagttga cagtagttta gtttctgtta
    24481 gtaataatgc aagtagctat gctaatcgta cgatggctag aatatcttct ttttactttg
    24541 atactgaaaa taacattatt aaggcgctgc ctgattcaga tagttctaag ttattaggaa
    24601 cgcctgcagc taatacagat atcattttgt ttagtgctaa tggaacaatt ttaaatgctt
    24661 ttgatgcgtt ttctaactat caaaattttc atttagataa acgccggttg gggagtattg
    24721 aaaccaccag tttaatgaat ttttatggac aagaagaaaa ataccatacg ataactgtaa
    24781 gggttcatat caaaaattat cctgcagttg cctatatgat ggcagtagta aatgtggaac
    24841 aattagaccg cgctaatgaa cgttacgagc gcattattat tatagttatg agtgtttttt
    24901 ggctaatttc tattttagca agtatttatt tagccaagtg gagcagaaaa cctattttag
    24961 aaagctatga aaaacaaaaa atgtttgttg aaaatgctag tcatgaacta aggacccctt
    25021 tggcggtctt acagaatcgt ctggaatcgc tttttcgtaa gcccaacgaa acgatattag
    25081 aaaatagtga gcatctcgct tctagtttag acgaggttcg caacatgcgc atcttaacaa
    25141 ctaatttatt aaatttagca agacgagatg atggcattaa tccacagtgg actcatttag
    25201 atacagattt ttttaatgct atttttgaga attatgaact agttgctaaa gaatatggaa
    25261 aaatatttta ttttcagaac caagtcaata gatcgttaag aatggataag gctttacta
//
LOCUS       DATTYN010000027        25287 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.27, whole genome shotgun sequence.
ACCESSION   DATTYN010000027 DATTYN010000000
VERSION     DATTYN010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25287
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.27"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(545..931)
                     /gene="rplQ"
                     /locus_tag="VB649_001370"
     CDS             complement(545..931)
                     /gene="rplQ"
                     /locus_tag="VB649_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEP1670318.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(946..1884)
                     /locus_tag="VB649_001371"
     CDS             complement(946..1884)
                     /locus_tag="VB649_001371"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEP1670319.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            complement(1930..2313)
                     /gene="rpsK"
                     /locus_tag="VB649_001372"
     CDS             complement(1930..2313)
                     /gene="rpsK"
                     /locus_tag="VB649_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEP1670320.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(2331..2696)
                     /gene="rpsM"
                     /locus_tag="VB649_001373"
     CDS             complement(2331..2696)
                     /gene="rpsM"
                     /locus_tag="VB649_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEP1670321.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDIR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNMNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(2714..2830)
                     /gene="rpmJ"
                     /locus_tag="VB649_001374"
     CDS             complement(2714..2830)
                     /gene="rpmJ"
                     /locus_tag="VB649_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEP1670322.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            complement(2856..3074)
                     /gene="infA"
                     /locus_tag="VB649_001375"
     CDS             complement(2856..3074)
                     /gene="infA"
                     /locus_tag="VB649_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEP1670323.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(3192..3830)
                     /locus_tag="VB649_001376"
     CDS             complement(3192..3830)
                     /locus_tag="VB649_001376"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEP1670324.1"
                     /translation="MNLLIIGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTE
                     MGRLAKSYIDKGELVPDEVTNGIVKERLAEDDIAEKGFLLDGYPRTIEQAHALDATLE
                     ELGLRLDGVINIKVDPSCLVERLSGRIINRKTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNMAQGEPILEHYRKLGLVTDIEGNQEITDVFADVEKALLELK"
     gene            complement(3980..5284)
                     /gene="secY"
                     /locus_tag="VB649_001377"
     CDS             complement(3980..5284)
                     /gene="secY"
                     /locus_tag="VB649_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEP1670325.1"
                     /translation="MFLKILKDALKIKTVRNKIFFTIFIILVFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSNVALVKTPDIKTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPSAIATIREDYFVNVKASDLHSSYLI
                     VGILIIAVLAIVFFTTYVQQAEYKIPIQYTKLMQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFVQNGRDLPWLNRLQEIFNYQTPVGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEQFMSALLKKLATVGAIFLAFISLAPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNTAE"
     gene            complement(5301..5741)
                     /gene="rplO"
                     /locus_tag="VB649_001378"
     CDS             complement(5301..5741)
                     /gene="rplO"
                     /locus_tag="VB649_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEP1670326.1"
                     /translation="MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIV
                     RAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI"
     gene            complement(5956..6138)
                     /gene="rpmD"
                     /locus_tag="VB649_001379"
     CDS             complement(5956..6138)
                     /gene="rpmD"
                     /locus_tag="VB649_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEP1670327.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIR
                     GMVTAISHLVTVEEVK"
     gene            complement(6153..6647)
                     /gene="rpsE"
                     /locus_tag="VB649_001380"
     CDS             complement(6153..6647)
                     /gene="rpsE"
                     /locus_tag="VB649_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEP1670328.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGR
                     VGFGTGKAQEVPEAIRKAVEAAKKNMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            complement(6666..7022)
                     /gene="rplR"
                     /locus_tag="VB649_001381"
     CDS             complement(6666..7022)
                     /gene="rplR"
                     /locus_tag="VB649_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEP1670329.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(7127..7663)
                     /gene="rplF"
                     /locus_tag="VB649_001382"
     CDS             complement(7127..7663)
                     /gene="rplF"
                     /locus_tag="VB649_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEP1670330.1"
                     /translation="MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIK
                     VEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            complement(7866..8264)
                     /gene="rpsH"
                     /locus_tag="VB649_001383"
     CDS             complement(7866..8264)
                     /gene="rpsH"
                     /locus_tag="VB649_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEP1670331.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEVIEDDKQGIIRVFLKYGKNGERVITNLKRISKPGLRVYAKRDDMPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(8415..8600)
                     /locus_tag="VB649_001384"
     CDS             complement(8415..8600)
                     /locus_tag="VB649_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEP1670332.1"
                     /translation="MAKKSMIAKNKRPAKHSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            complement(8616..9158)
                     /gene="rplE"
                     /locus_tag="VB649_001385"
     CDS             complement(8616..9158)
                     /gene="rplE"
                     /locus_tag="VB649_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEP1670333.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            complement(9182..9487)
                     /gene="rplX"
                     /locus_tag="VB649_001386"
     CDS             complement(9182..9487)
                     /gene="rplX"
                     /locus_tag="VB649_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEP1670334.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKH
                     QKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD"
     gene            complement(9566..9934)
                     /gene="rplN"
                     /locus_tag="VB649_001387"
     CDS             complement(9566..9934)
                     /gene="rplN"
                     /locus_tag="VB649_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEP1670335.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            complement(9959..10219)
                     /gene="rpsQ"
                     /locus_tag="VB649_001388"
     CDS             complement(9959..10219)
                     /gene="rpsQ"
                     /locus_tag="VB649_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEP1670336.1"
                     /translation="MERNQRKTLYGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEKAVII"
     gene            complement(10245..10451)
                     /locus_tag="VB649_001389"
     CDS             complement(10245..10451)
                     /locus_tag="VB649_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEP1670337.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     EKTARLDEVKKQIARVKTVQSEMK"
     gene            complement(10461..10874)
                     /gene="rplP"
                     /locus_tag="VB649_001390"
     CDS             complement(10461..10874)
                     /gene="rplP"
                     /locus_tag="VB649_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEP1670338.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(10878..11531)
                     /gene="rpsC"
                     /locus_tag="VB649_001391"
     CDS             complement(10878..11531)
                     /gene="rpsC"
                     /locus_tag="VB649_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEP1670339.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELADASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRGQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(11544..11888)
                     /gene="rplV"
                     /locus_tag="VB649_001392"
     CDS             complement(11544..11888)
                     /gene="rplV"
                     /locus_tag="VB649_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEP1670340.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            complement(11904..12182)
                     /gene="rpsS"
                     /locus_tag="VB649_001393"
     CDS             complement(11904..12182)
                     /gene="rpsS"
                     /locus_tag="VB649_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEP1670341.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            complement(12321..13154)
                     /gene="rplB"
                     /locus_tag="VB649_001394"
     CDS             complement(12321..13154)
                     /gene="rplB"
                     /locus_tag="VB649_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEP1670342.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKSKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLANIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATIGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(13172..13468)
                     /locus_tag="VB649_001395"
     CDS             complement(13172..13468)
                     /locus_tag="VB649_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEP1670343.1"
                     /translation="MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(13468..14091)
                     /gene="rplD"
                     /locus_tag="VB649_001396"
     CDS             complement(13468..14091)
                     /gene="rplD"
                     /locus_tag="VB649_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEP1670344.1"
                     /translation="MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            complement(14115..14741)
                     /gene="rplC"
                     /locus_tag="VB649_001397"
     CDS             complement(14115..14741)
                     /gene="rplC"
                     /locus_tag="VB649_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEP1670345.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAG
                     RMGGNRVTVQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            complement(14989..15297)
                     /gene="rpsJ"
                     /locus_tag="VB649_001398"
     CDS             complement(14989..15297)
                     /gene="rpsJ"
                     /locus_tag="VB649_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEP1670346.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(15496..16785)
                     /locus_tag="VB649_001399"
     CDS             complement(15496..16785)
                     /locus_tag="VB649_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEP1670347.1"
                     /translation="MIYNRRKIFSLALPSMIENILQMLMGMVDNYLVAQIGLLAVSGV
                     SIANNIISIYQSLFIALGAAVSSLIARSIGENNQNKQLNYMAGVLQVTLLLSVGLGLL
                     SVVGHHQVLEWLGAEASVTLVGGQYLSIVGGMIVSLGLLTSLGAIVRAQGYPKIPMQV
                     SLLINVLNAIFSALSIYVWGFGLLGVAWATVLSRLVGVFLLCQFIPIKQVAKRLMRPL
                     DKIIFDLSLPAAGERLMMRAGDVLIIGIIVRFGTTALAGNAIGETLTQFNYMPGLAMA
                     TATIILVARQLGGGKVTEIRYIIREAFILSTLMMLVMGALTYLLGPSLLPLFTQNTDA
                     QRSAMVVLLFSLLGAPATAGTLVYTAVWQGLGKAKLPFYATTVGMWVIRIGLGYVIGV
                     VWQYGLIGVWMATVLDNTSRWFILSKQFKKYQEITFH"
     gene            complement(17173..18189)
                     /gene="adhP"
                     /locus_tag="VB649_001400"
     CDS             complement(17173..18189)
                     /gene="adhP"
                     /locus_tag="VB649_001400"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEP1670348.1"
                     /translation="MKAVVVNQASTGVEVVEHDLPKVGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEEIGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPEGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADILVNGKEIE
                     DVPGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVDTAPEVFDEMERGLIQGRKVL
                     DFIS"
     gene            complement(18441..21083)
                     /gene="adhE"
                     /locus_tag="VB649_001401"
                     /gene_synonym="adhC"
     CDS             complement(18441..21083)
                     /gene="adhE"
                     /locus_tag="VB649_001401"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEP1670349.1"
                     /translation="MTEGHNTVETTSVSVTINALVQKGLAALEEMRKLDQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPENCVQWVETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIVDKEIYDDFVAEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPATWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKSESREDGVEKARQMVEFNGLGHSAAIHTAD
                     AELAKEFGTRIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNAVGDNVSAIN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFAEVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFDNLEKSVKTADFEAREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEAVESYAKAVYDLGCRVGIQMNFKAQGIDENEWKEHSRELAYLAYEDQCSPANPRLP
                     MVDHMQEIIEDAYYGYAERPGRRK"
     gene            complement(21392..23167)
                     /locus_tag="VB649_001402"
     CDS             complement(21392..23167)
                     /locus_tag="VB649_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEP1670350.1"
                     /translation="MRIKWFSFVRVTGLLLVLLYHFFKNVFPGGFIGVDIFFTFSGYL
                     ITALLIDEYTKKESIDIIGFLKRRFYRIVPPLVLMILLTIPFTFLIKKDFIANIGSQI
                     TAVLGFTTNIYEILTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGVFVWLLARRKETQ
                     KQLRGLLFLISLGIFAISFLSMFIRSFMTSNFSLIYFSSLSHSFPFFLGAMFATITGI
                     NETTVRFQKNVRLWPRQYVLAAMVGAFTLLLVLTVTLDFNHITTYLFGFALASLFASI
                     MIYAARVLHEQTPDVQEPKAITYIADISYGIYLFHWPFYIIFSQLMSHILAVILTVFF
                     SILFATVSYYIVEPLVQGRKPNLLGLEIDCSPYYKWIVGGTLALALLTLGTCMIAPKV
                     GKFEKQLLVSSLQQAQSNMERTHTLAAGDANALSDVGIIGDSVALRSSAAFSKIMPQA
                     QLDAAVSRNFKEAFDLFNNQIKSKSLSKTVVLAVGVNSLDNYSQAVQSFIEALPKGHR
                     LVLVSPYNAKNASQVAEARDYGLKLSKKYKYVTIADWYKVAVGHPDIWYGSDGVHYSE
                     DSQGAELYVSTIQTAVEKSAKKPAK"
     gene            complement(23164..23565)
                     /locus_tag="VB649_001403"
     CDS             complement(23164..23565)
                     /locus_tag="VB649_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670351.1"
                     /translation="MIDMQDIVKKWSITRAKLEIVSVIVILVCAISVFSVRISNKTSL
                     TYDKGRMHYTGYVINHKMNGEGKLVYPNGDIYEGTFKNGLFEGKGTFTAKTGWLYNGE
                     FHKGQANGKGVLKAKNNKVYKGIFKQGIFQK"
     gene            complement(23588..24025)
                     /locus_tag="VB649_001404"
     CDS             complement(23588..24025)
                     /locus_tag="VB649_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEP1670352.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHG
                     NPIHSGTQSILKTYQINYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWD
                     SKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY"
     gene            complement(24163..25161)
                     /gene="ruvB"
                     /locus_tag="VB649_001405"
     CDS             complement(24163..25161)
                     /gene="ruvB"
                     /locus_tag="VB649_001405"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023079556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEP1670353.1"
                     /translation="MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEA
                     AKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELE
                     PGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPR
                     IANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGG
                     PVGLGTLSVNIAEERNTVEEVYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT"
     gene            complement(25208..>25287)
                     /locus_tag="VB649_001406"
     CDS             complement(25208..>25287)
                     /locus_tag="VB649_001406"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEP1670354.1"
                     /translation="YYFIFAALLSFKVVQELSAVDWWRL"
BASE COUNT         7467 a         5335 c         4455 g         8030 t
ORIGIN      
        1 ttttttgtac ttttttacaa ttttgttgga aacggcttaa agtgacagat tttaaaagta
       61 aaaaagatat tttcacctcc aaattaaaag aggattttag aatacttatt aataaaatat
      121 tgaatagggg ataaaactaa caatatagtt tgagcatctg tttgcgatgc aagttttttt
      181 cggacattta aacgagggga ttacaccgtt tatttgccca tgagagattt ttaaacacct
      241 gcataaggtt ttcttattct gatgacctta ttgtctctga gaaaacttta taaacgcatc
      301 agaagaggct tctgtgttat tgttttgctc agcttaaaag cggggggtgt tcacctcata
      361 atacaacaaa acgcctgctt ataaaaagtt tctatagctt agataccttt cataaacaag
      421 cgttacatat taacaatatg atgagtgttc ccgctaggaa aaatcctagc ggtagaccag
      481 agctagacta agaataatct ctcgattact ccatcatcat aacactcaac aaaattgata
      541 aaaattaaac taattcaata attgccattg gagcagcatc tccacggcgt ggttctgttt
      601 taagaatacg agtgtatcca ccgttacgtt ctgcataacg aggtgcaatt tctgagaaaa
      661 gtttttgaag agctgtcgtt gatgtgtatt tatcggtagc ttcatcataa ttttctgatg
      721 cgatttcgtt acgaacgtat gcagctgctt ggcgacgagc atgaagatca ccacgtttac
      781 caagagtaat cattttttca actgttttac ggatttcttt tgcacgtgct tctgtcgtta
      841 caattgattc gttgatcaaa agatctgtcg tcaaatcacg aagcattgct ttacgttgtg
      901 agctagtgcg tcctagttta cggtaagcca ttttgtcctc ctatattatt tatcgttttt
      961 tagtccgaga cctaagtcag caagtttaac cttaacttct tcaaggctct tacgtccaag
     1021 attacggact ttcatcattt caggctcaga tttttctgtt aagtcgaaga cagtgttaat
     1081 gcctgcacgt tttaaacagt tatatgagcg tacggataaa tcaagctcct cgatggtgcg
     1141 gtcaagtacc ttttcatcgt tcactttttc agtttctttc attacttcgg tagcttttgc
     1201 aacctctgtt aaatcagtaa acaggtttaa gtgttcgatc aaaactcgag cagatagacc
     1261 taaagcatct tcaggaataa ttgttccgtt tgtcatgatt tcaatcgtta atttatcaaa
     1321 gccatcattg ctacctacac gggcaggttc aacttgataa ttaacttttt taactggcgt
     1381 atagattgaa tctactgcca atgtacccac aggtgcatca tcttttttgt tgccttctgc
     1441 tggcacataa ccacgttttt tagcaacagt cattgttgca cgtagagaat gtccttcagc
     1501 gattgtaaaa agataatgat ccgggttaac aagttcgata tcactgtcag taagaatatc
     1561 accagctgtt acctctgctg gtccttctac ttcaagttcg ataatctttt cgtcttcgac
     1621 gtatgatttc acagcaagtc ccttaacatt aaggataatt tgcatgacat cttcacgtac
     1681 acctgggatt gtatcaaatt cgtgtagtac tccatcaatt ttaattgatg ttactgctgc
     1741 acctggaagt gaagacaaga gtacacgacg aagagaatta cctagagttg ttccgtagcc
     1801 acgttcaagt ggttcgatga caaatctacc gtaatcttta ttttcatcaa tttttgttat
     1861 tattggtttt tcaaactcaa tcattttttc acccctcgaa acgaaacttg tgtactattt
     1921 gttatatgat tatacacgac gacgttttgg aggacgagca ccattatgtg gcacaggggt
     1981 cacatcacga attgcagtta cttcaagacc tgcagctgct agagcacgaa tagctgattc
     2041 acgacctgaa ccaggacctt ttacagtcac ttcaacagtt tttagtccgt gttcttgtgc
     2101 agattttgca gcagcttctg cagccatttg agcagcaaat ggagtagatt tacgagaacc
     2161 tttgaaacca agagcaccag ctgatgacca tgcaagagca ttaccatgca catctgtaat
     2221 cataacaata gtgttattaa atgtagcgtg aatgtgtgca acaccagatt cgatgttctt
     2281 tttcacacga cgtttacgtg ttggtttagc caattgtttt acctcctatt ttattttttc
     2341 ttacctgcaa tcgcaacagc tttcccttta cgagtgcgag cattgttttt agtattttgt
     2401 ccacggacag gaagtccacg acgatgacgg attccacggt atgaaccgat ttccatcaaa
     2461 cgtttaatgt tcatgtttac ttcacgtcga aggtcacctt caactttgat tgcatccact
     2521 tcacgacgga tagcatcttc ttgatctgat gttaaatctt taacacggat atcttcagaa
     2581 atacctgcag ctgctaagat ttttttagat gttgcaagac caattccgta aacataagta
     2641 agtgaaatta ctacgcgttt atcatttgga atatcaactc cagcaatacg agccattttt
     2701 tctcctttct attttatcct tgacgttgtt tgtgttttgg atttgtcgga caaattacca
     2761 taacacgacc attacggcga ataactttac agtattcgca aattggttta accgatggtc
     2821 ttaccttcat gttttaatcc ctccaattat ttcgattatt taaagcggta tgtgatgcgt
     2881 ccacgtgtca agtcataagg actcatttct actgtaacac ggtcacctac taaaatacga
     2941 atgtaatttt tgcggatttt tcctgataca gttgctagaa tttgatgtcc attttccaat
     3001 tcaacagtaa acattgcatt tggcatcgtt tctactactt tgccttcaat ttcaatcacg
     3061 tcttcttttg ccacgcaaaa gtacccccta aatttcgatt tgatgtcctc tgagcacaga
     3121 ggtaacaatt ataagtcaga ctaaactagt atatcattac taatctactt atgcaagtag
     3181 attagtataa tttatttgag ttctagcaac gctttttcaa catctgcaaa aacgtctgtt
     3241 atttcttgat taccttcaat atctgtaaca agaccaagct tacgatagtg ttcaagaata
     3301 ggttctcctt gagccatatt gacgtccaaa cgacgtttaa cagtttcagg cttatcatct
     3361 tcacgttgat agtaatcttc ttctttataa tctactggtg ggttgaacac tttatggaac
     3421 gtttcaccag ttttacgatt gataatacga ccactcaaac gctctacaag acatgatgga
     3481 tccactttaa tattaataac accatctaag cggagtccta gttcttcaag tgttgcatct
     3541 aaggcgtgtg cttgttcaat agtacgtgga tacccatcaa gcaaaaaacc tttttctgcg
     3601 atatcatcct cagctaagcg ctcttttaca atcccgtttg tgacttcatc aggaaccaat
     3661 tcacctttat caatataact tttagctaaa cgtcccattt cggtttgatt agccattgcg
     3721 gcgcggaaca tatcccctgt tgagatgtga gcaacaccaa attcttcaac aatcttagct
     3781 gcttgggtcc ctttaccagc tcccggcaaa cctatgatta aaagattcat cttttcctcc
     3841 tcttttaaaa taaatacata gtaggaaatt attttccttg gtttttgttt tcaaatggca
     3901 acaagaaatc gtttgatgat aaccaagtct tattgtcatt taaaaacaaa atagaaggtt
     3961 gacaatgtca acctgtattc tattctgctg tattcataaa tccgacatat tttctcttta
     4021 gaagatatcc ctcaagctgt ttcatacctt cgataccagt tgaaatcaaa atgagcaaac
     4081 tagttccacc taaagcaata ctagaagaaa ggttgagagc ttgttgtgct gctattggcg
     4141 ctaaagagat aaatgctaag aagatagctc ctacggttgc tagttttttt agcaatgcgg
     4201 acataaattg ttctgtctca cgtccagggc gaacacttgg tatatatgag gaattcttct
     4261 gaagattttc tgctgtcttc tcaggattaa cttgtacaaa agtatagaag aatgagaaca
     4321 atataatcaa caaggcgtaa actatcattc cgactggagt ttgataatta aaaatttctt
     4381 gcaaacggtt taaccacggt aaatctctac cattttgaac aaaaggaata atcgtacttg
     4441 ggatagttgt aatcgagcta gcaaagataa cgggaataac gccggctgga tttactttta
     4501 atggaagata tgaacttgta ggtgcacctt gcattagctt tgtgtattgg attggaattt
     4561 tatattccgc ttgttggaca tatgttgtaa agaaaacaat agcaagaaca gctatgatta
     4621 aaatcccaac aatgagataa gacgagtgta aatcacttgc cttaacattt acaaaatagt
     4681 cttcacgaat tgttgcaatt gcacttggaa tagacgaaat aatacccgca aagataatca
     4741 ttgatacgcc attaccaaat cctttatctg tgatttgttc tccaagccag gtaacaataa
     4801 cgctacctgt tgtcagtaat gccccgatca gtaaatatgt tttgatgtct ggtgtcttaa
     4861 caagtgcaac gttcgacaaa gtattaaacc ctgcagtgat accaatggat tgggcaaaag
     4921 ccaaaacaag tgaaatatag cgcgtcgctt gatttaattt acgacgtcca acctcacctt
     4981 gtttgcccca ctcaacaaac ttaggtaaaa tatccatctg caataactga acaacgatag
     5041 aagcagtaat atatgggcta acccccattg aaaatactga gaaatttctc atcgcattac
     5101 cactaactaa gtttaacata tttaagaaag ggagttcact taattgctct aaactcttgg
     5161 catttacacc aggtacggta atatgtgtcc caattcggaa tacaagaatg ataaatatag
     5221 taaagaaaat tttattccgt acagtcttta tctttaacgc gtcttttagt atttttaaga
     5281 acataatgag tatcccctca ttagatgact tcgatcgaac cacctttagc aataatagct
     5341 gcttcagcag attttgagaa cttagctgct tttacagtca attttttagt caattcaccg
     5401 ttaccaagca ctttaacgcc tgatttttca gctcggacaa taccagcatc ttttaaaata
     5461 gccggagtca cttctgtacc atcatcaaaa acattcagtt gatcaagatt cacaagtgca
     5521 tattctttag tattaatatt tgtaaagcca cgttttggaa tacgacggaa caatggtgtt
     5581 tgtccacctt caaaacctaa acgtacaccg ccaccgctac gagctttttg acctttttga
     5641 ccgcgaccag atgttttacc attacctgat gatgtcccac gaccaacacg gttacgtact
     5701 ttacgtgagc cttcagcagc ttttaattca tgaagtttca ttttttctcc tttttttgta
     5761 aaatgctagc gcctctatga gggaaaagga ctccctatag aaactcgcct atacattaat
     5821 gatacttaag ttatccaaaa taacttaata cagatacgca ctaaccgact actgtttgtt
     5881 gccaaaaaag caaactacaa gagtcggttt tgtgctcgtt tttaattatg aaatcagaga
     5941 tttcacagtt ataatttatt taacttcttc aacggtaacc aagtgagaaa tagctgtcac
     6001 cataccacgg atagcagcat tatcttcttt gactactgaa gagtttaatt taccaagtcc
     6061 aagagcaaca acagttttac gttgttctgg cttacgtccg ataggagact tagtcaaagt
     6121 aattttaatt tgagccatga tgatcccctt tcttatgcta agtcagaaac tgagatgcca
     6181 cgaagtgcgg caacttcttc tgcacgttta agttgtttca atccttcaac agttgcacga
     6241 acaatgttga ttggagtgtt tgaaccaaga gattttgaag taatatcagc aacacctgct
     6301 aattcgatga cggcacgaac tgcaccacca gcagcaactc cagaaccttc tacagctggt
     6361 ttcaataata ctttagctcc accgaagtta gtgtaaactt cgtgagggat tgttgtacca
     6421 accattggta cttcgatcat gtttttctta gcagcttcaa ctgctttacg gatagcttct
     6481 ggaacttctt gagctttacc agtaccaaat ccaacacgac catttccatc accaacaact
     6541 acaagagctg caaagcgaag acgacgtcca cctttaacaa cttttgtaac gcggttaatc
     6601 gcaacaacgc gttcttcaag ttcaactgca ttatctttaa atgccattat tttgtgtcct
     6661 ccctattaga atttcaatcc gttttcacga gctgcatcag ccaaggcttt aacacgtccg
     6721 tgatagagat atccaccgcg gtcaaacacc acttcagaaa tacctttagc cactgcacgt
     6781 tcagcaacaa gtttgccgac tacaacggct tgttctgttt ttgttccttt agaaacgtct
     6841 ttatcaagag ttgatgcact tgcgagcgtt acacccgcta cgtcatcaat aacttgagcg
     6901 tagatgcctg tattagaacg gaatacgttc aaacgtgggc gatcagcagt tccagagagt
     6961 ttaccgcgga cgcgacggtg gcgtttttgg cggattttgt ttttatctgg tttcgaaatc
     7021 acaattttca cctcttaatt ttaatcaatt tgtctcattg acaagttgtc gattgaactt
     7081 atcgagcatg ttaaggtgca atacttccca tacccgacta agaacattat ttacctgttt
     7141 taccttcttt aaggcgtacg tattcaccaa cgtaacggat ccctttgcct ttgtaaggct
     7201 ctggtgaacg caagctacgg atgtaagcag ctgtttgacc aacaacttct ttgttgattc
     7261 cttcaactga gattgaagtt gggttagcaa cagtgaaagt aattccttct ggagcttcaa
     7321 cttcgtcttg gtgagattta cctactgaaa ggacaagttt agtaccttga agttgagcac
     7381 ggtaaccgac acccttcatt tcaagatctt ttttgaaacc ttcagaaaca cctacaacca
     7441 tgttattcaa gttagcacgg gttgtaccat ggattgtttt catttctttt gagtcgttag
     7501 gacgtacaac tgtgatttca gtcccttcaa ctttgatttc aatatttttg ttgaactcac
     7561 gagtgagttc gcctttaggg cctttaacag taataacatt gttgttattt gttaattcaa
     7621 cacctgcagg catagtaatt actttattac caatacgtga catgtttgtt ttctcctgtt
     7681 aaattgtcaa gccgcatagc gactagtttt cacgggggtt tgatagaatg atatacttca
     7741 atttatattt caaaattgaa cacgagctgt ggcctgtgtg aaaaagataa atcctccttg
     7801 agtgtaaaca cgctacgtca gatttcctat tttcactttg tccacgacgc tcttagtatc
     7861 ttaaattacc aaacgtaagc gatcacttct ccaccaacat tcttttggcg agcttctttg
     7921 tcagtcaaaa gaccttctga tgttgaaatg attgcaattc caagtccgtt aagaacttta
     7981 ggcatgtcat cacgttttgc gtaaacgcga agacctggtt ttgaaatacg ttttaagtta
     8041 gtgataacac gctcaccatt ttttccgtat tttaagaaca cacgaatgat accttgttta
     8101 tcatcttcga taacttcaac attttttaca aaaccttcac gtttaagaat ctcagcaatc
     8161 ccttttttaa tgtttgaagc aggtacttct aacacttcgt gttttacttg attagcatta
     8221 cggatacgtg ttaaaaagtc tgcaattgga tcagtcataa ccatttttta tattctcctc
     8281 ttactagcag tttgatgcta tcacttacta gttaatgttg tccttaaagg actttggtat
     8341 cagcttatgc tcacaccgtt ttaattaagc acaagactca atctgaagaa caaattaagt
     8401 tttgtgtcat atttttacca agaagctttg acaacacctg gaatttgacc tttgtaagcc
     8461 aattcacgga agcaaacacg acaaagttta aacttgcggt aaactgaatg tggacgtcca
     8521 catttttcac agcgagtata agcttgtgta gagtgttttg caggacgttt gttcttagca
     8581 atcatagatt ttttagccaa tttatttacc ccctattatt ttgcaaaagg cattccaagg
     8641 cccttaagca attcacgtga ttcttcgtca gtatttgcag tagtgacgat tacaatatca
     8701 agaccacgta ctttatcaac atcatcaaag ctgatttctg ggaagataag ttgttctttc
     8761 acaccgagag tgtagtttcc gcgtccatca aacgattttg ttggaacgcc atggaagtca
     8821 cgtacacgag gaagtgaaac gctaaccaat ttgtctagga attcgtacat acgttcgcca
     8881 cggagggtaa cttttgcacc gatcgctaca ccttcacgaa gacggaagcc agcgattgat
     8941 ttcttagctt tagtaataag tggtttttga cctgagataa gtgctaattc agctgcagct
     9001 ttctctaggt tttttgcgtt ggatacagca tcaccaacac ccatattgag aacaattttc
     9061 tcaacttttg gcacagccat aactgatgtg taattgaatt tctctgtcaa cgcaggaatt
     9121 acttcgttag tatatttttc ttttaaacga tttgccatta tgcttctcct ttccttcgtg
     9181 attaatcaag cacttcgcct gattttttgc tgtaacgtac ttttttaccg tcaacaactt
     9241 tataaccaac acgtccagct acaccatttt tatctaatac ttgaacatta gagacatgga
     9301 taggtgcttc tttttcgacg atagctcctt gaggattttc agtgttaggt ttttggtgtt
     9361 ttttaatcat tccaacacct tcaacaataa ctttgttaac ttttggaagt gctttaagaa
     9421 ctacagcttc agtgcctttg tccttgccag caattacgcg aactttgtcg ccttttttta
     9481 caaacattct ggtttctcct attatttctt acgccccgat gggcacccta ggaaaaccta
     9541 ggggactacg tttgttaacc tgagattaaa gtacttctgg tgcaagtgat acgattttca
     9601 tgtagccacc ctcacgcaat tcgcgtgcaa ctgggccaaa gatacgagtt ccgcgaggag
     9661 ttttatcatc acggatgatt acagcagcat tgtcgtcaaa tttgatgtat gaaccgtctg
     9721 gacggcgtgc accagttttt gtacgaacga taacagcttt aaccacatca ccttttttaa
     9781 ctgctccacc aggagtagct tgttttacag aagcaacgat tacgtcaccg atgttagcga
     9841 atttacgtcc tgaaccacca agtactttga tagtcaagat ctcacgagca ccgctattat
     9901 cagcaacttt caagcgagtt tcttgttgaa tcatttcaat tttctccttt tagtttgatt
     9961 agataataac agctttttcc actacttcca caagacggaa acgttttgta gctgaaagtg
    10021 gacgagtttc catgatacga acgatatcgc cttctttagc aacgttgttt tcgtcatgtg
    10081 ctttatattt tttagaatag ttgatacgtt taccatagac tgggtggtta cgtttagttt
    10141 caactacaac tgtgattgtt ttgtccatct tgtcagacac tacgcgtccg taaagagttt
    10201 tacgttgatt acgttccatt tagaatttct cctttcccaa tctattattt catttctgat
    10261 tgcacagttt taacacgtgc aatttgtttc ttaacttcgt caaggcgagc agtcttttca
    10321 agttgacctg ctgcagcttg gaaacgaaga tcaaacaatt cttttttgag ttcgttttct
    10381 ttcttagcaa gttcttcttg agacaatcca cgaagctctt taacaaaatc tttaatttct
    10441 tgaagtttca tgtcttctcc ttattctgct tcacgtttta cgaatttgca cttaactggt
    10501 aatttgtggc tagcaagacg taatgcttcg cgagcaattt cttcagaaac accagcaatt
    10561 tcaaacatca ctttaccacg tttaactggt gctacccaac cttcaggtgc ccctttacca
    10621 gaacccatac gtacaccgat agcttttgca gtgtatgatt tgtgtgggaa gattttaatc
    10681 caaactttac caccacgttt catgtaacga gtcatcgcaa tacgggcagc ttcgatttga
    10741 cggtttgtaa tccagtggct agttgtggct tgaagtccgt attcaccgaa tgaaacttct
    10801 ttaccacctt tagcctcacc gcgcattttt ccacggaatt cgcgacggtg tttaacacgt
    10861 ttaggtacta acatttgtta tttgcctcct ttagtgtttt tacgagctgg aagaacttct
    10921 ccacggtaaa tccaaacttt aacgccaagt ttaccataag ttgtgtcagc ttcttcccaa
    10981 gcatagtcga tatcagcgcg aagcgtgtga agtggaacag ttccttctga ataaccttca
    11041 gcacgagcga tatcagcacc gttcaaacga ccagaaactt gagttttaat ccctttagct
    11101 cctgcacgca ttgtacgttg gattgcttgt ttttgagcac gacggaaagc aacacgttgc
    11161 tcaagttgac gagcaatgtt ttcaccaaca aggtgagcat ctaaatcagg ttgtttgatt
    11221 tcgatgatgt tgatgtgtac ttgttttcca gttaatttgt taagttgacc acgaagagcg
    11281 tcaacgtttg cgccaccttt accgataacc atacctggtt tagcagtgtg aagtgaaaca
    11341 ataactttgt ttactgcacg ttcaatttca atagttgaaa ctgatgcgtc agctaattct
    11401 ttattaatga atttacggat tgcaagatct tcatgaaggt aatccgcgta ttctttttca
    11461 gcataccatt tcgcatccca gtcacggatg attccgacac gcataccaat tggatgtact
    11521 ttttgaccca cgattttacc tccttatttt tctgatacaa ctacagttac gtgagttgta
    11581 cgtttgttga ttggtgaagc tgaacctttc gcacgtggac ggaaacgttt cattgttggt
    11641 ccttcgttag cgaatgtttc agatactacc aagtttgctt tttccaaacc aaagttgttt
    11701 tctgcgttag caattgctga gttaagagtt ttctcaataa cacgagctgc tttgtttgga
    11761 gtgaatttta agattgcgat tgcgtcagca actttcttac cacggataag atcaagtact
    11821 aaacgtgttt tacgaggtga aacacgcact gtacgagcca ttgctttagc tgaagtaatt
    11881 tctgccattg tgtcctcctc ctattaacga cgtgttttct tgtcgtcagc tgcgtgacct
    11941 ttgtaagtac gcgttggtgc aaattcacca agtttgtgac ctaccatgtc ttcttggatg
    12001 taaacaggta catgtttacg tccgtcataa actgcgattg tatatccgat gaaacttggg
    12061 aaaatcgttg aacgacgtga ccaagttttg attacttttt tcttttcgtc gtttgcttga
    12121 gcttcaactt ttttcatcaa atgctcatcg acgaaaggtc cttttttaag actacgtccc
    12181 attttgtagt tttctccttt aaataatgta ccacagcggc ttgaattcaa gagcaagact
    12241 ccaaactcta ccgagttggc ggaataaata gcaaagctat tgtaacgcta tttcagcaag
    12301 ttttaagcaa cttactaaga ttatttttcg ttacgacgac gaacgataag tttgtctgat
    12361 ttagctttct tgttacgagt tttaagacca agcgctggtt taccccatgg agttgatggc
    12421 gctttacgtc caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc
    12481 attacagaac cacgaactgt tgggcggata cctttccaac ggctacgtcc tgccttacca
    12541 atattaacaa gtgattgttg ttcgttacca acagtaccga tagttgcacg gcatgtacca
    12601 agaatcatac gaacttcgcc tgattgaaga cgaacaagaa cgtatttacc ttcttgacca
    12661 agtacttgag cagaagctcc agctgcacga acaagttctc cacctttacc aggtttcaac
    12721 tcaatattgt gaacaactgt accgacagga atgtttgcta atggaagtgc gttaccaact
    12781 ttgatatctg catctggacc agaaacaata cgttgaccta cttcaagacc tttaggtgca
    12841 atgatgtaag ctttcacacc gtcagtgtaa tgtacaagtg cgatgtttgc agtacggttt
    12901 ggatcgtatt cgattgtttt aacaactgct tcaacgccat ctttgttacg tttgaagtcg
    12961 atcaaacggt aatgacgttt gtgtccacca ccttggtgac gaactgtgat gcgaccattg
    13021 ttgttacgac cagctttgct cttaagagaa acaagcaatg atttctcagg cgtgcttgtt
    13081 gtgatttccg cgaaatccaa agaagtcatg ttacgacggc catttgtcgt tggtttataa
    13141 actttaatac ccacgttatt tcctccttag attattcagc ttcagctgcg aacaactcga
    13201 ttgctttaga atcagctgta agagtgatga tagctttttt agtttttgaa gtgaaacctg
    13261 tgtaacgacc aacgcgtttt gcttttggtt taacgttaac agtgtttaca cttgcaactt
    13321 taactccgtc aaaagcagct tcaacagctt gtttgatcaa aagtttgtgt gcacgagtat
    13381 caacttcgaa agtgtatttg cctgcttcaa gagcaatcat tgacttctca gtgataactg
    13441 gttttttgat tacgtcgtac aaattcatta tgcaagaacc tcctcaattg tagagattgc
    13501 ttctttagta acaagaagtt tgtctgcgtt cacgatatca agaacacttg cagttgctgc
    13561 agttgcaaca gttacgtttg gaaggttacg tgcagaaagt gctgcaaatt catttccttc
    13621 ttcaacaaga acaagtactt ttgtatcaat gctaagagct gaaagcactt ttgcaaattc
    13681 agcagttttt ggtgctgcaa atgaaaggcc ttctacagct acaaatttat cttcagcaac
    13741 ttttgctgag taaactgatt tcaacgcaag gcgacgaact ttttgtggaa gtttgtatcc
    13801 gtatgaacgg ggagttggtc caaagacaac accaccacca cgccattgtg gtgagcggat
    13861 agaaccttga cgagcgcgtc cagttccttt ttgacgccat ggtttacgtc caccacctga
    13921 tactgctgaa cggtttttaa ccgcatgagt accttggcga aggctagcgc gttggctaat
    13981 tacaacatca aaaacaactg attcgtttgg ttcgataccg aagatagcgt cgtttaattc
    14041 aactgagcta acttctttac cagtttggtc aaatagtttt acgtttgcca ttttaactgt
    14101 tttctccttt cttattattt agcagcttta actgctgact tgatagtgat aagagatttc
    14161 ttagcacctg gtacgttacc tttaataagg ataacgttct tttctgggat aacttgtaca
    14221 atttcaaggt tttgaactgt tacacggtta ccacccatac gtcctgccaa gcgtttgttt
    14281 ttgaaaacgc ggttaggcgc aacaggtccc atagaacctg ggcgacgatg gtaacgagaa
    14341 ccgtgagcca taggaccacg tgattgacca tggcgtttga taacaccttg gaaaccttta
    14401 ccttttgatg tccctgtgac gtcaacaaca tcaccagctt caaattgttc tacagataat
    14461 tctgcaccaa cttctaagcc ttcaatgttt ttgaattcac gaatgaagcg cttaggagct
    14521 gtgtttgctt ttgcaacatg gcctttggca ggtttgttac tcaagacttc acgtttgtca
    14581 tcaaaaccaa cctgaactgc ttcataaccg tctgtttcaa cagttttaac ttgaagcaca
    14641 acgtttggag ttgcttcaat gacagtaaca gggatgaatt cgcctgattc agtgaagatt
    14701 tgagtcattc ccactttttt ccctaagatt ccttttgtca tgagaaaata tttccttttc
    14761 ttaataatat ttcaaaaagt tttttatgag cgttttttgt gctcaaaaaa gttttttacg
    14821 agcgtttttt gtgctcatag caagatacaa agagcgtcaa actcaaaata aaaatagaaa
    14881 atctaacaca aaaacttctg tttcgaggaa gatttatctt tttcatgtag agtttagctc
    14941 gtgttcaagt tccatcaaac actaactgta cttgcaaaat ctcaccgatt aaagtttgat
    15001 ttctacgttg acaccacttg gaagatcaag tttcatcaaa gcatcaacag ttttttgtgt
    15061 tggattgatg atgtctacca aacgtttgtg tgtacgcatt tcaaattgtt cgcgagaatc
    15121 tttgtatttg tgagtcgcac gaataattgt gtaaagactg cgttcagttg gaagtggaac
    15181 tggtccagca actgtagcac ctgtacgtgt tgcagtttca acgatttttt ctgccgctgt
    15241 atcaagtgta cggtgttcgt acgctttcaa acggatacgg atttttttgt ttgccatctt
    15301 ttctcctctc gtctatttac gataataggc tagctcctca agaaaaccga cacctgttgc
    15361 gtggcaatgc aaccgagcgt gtcgcaacct cttgtatcat tgctaaagct gtatttttac
    15421 agcaccacaa tataataaca gaatcattta gtcattgcaa gctttttagg cattttttca
    15481 aaaaaaacta ccttcctaat gaaaggtaat ttcttggtac tttttaaatt gtttagaaag
    15541 aataaaccac cgactggtat tatctaacac tgtcgccatc cagaccccta tgagtccata
    15601 ttgccaaacc acaccaatca cataaccaag gccaatgcga attacccaca ttcctacggt
    15661 tgttgcatag aaaggaagct ttgcttttcc caaaccctgc cagacggctg tataaactaa
    15721 agtgcctgcc gttgcgggag ctcctagtaa agaaaaaagt aaaacaacca tggcggacct
    15781 ttgagcatca gtattctgag taaatagcgg caagagacta ggacctagca gataggtcaa
    15841 ggctcccata accagcatca tgagggtgga taaaataaaa gcttctctaa taatatacct
    15901 tatctcagtc accttaccgc cccccagttg cctagccact agaataattg ttgccgttgc
    15961 catggctaag ccaggcatgt aattaaactg agtcaaggtt tctccaatag cattacctgc
    16021 caaggccgtt gtcccaaagc gaacaataat gccaataatt aggacatctc ctgctctcat
    16081 catcaaacgt tcaccagcag caggtagtga taaatcaaaa ataattttgt ccaaaggtct
    16141 catcaatcgt ttcgcaacct gtttaatagg aataaactga caaagtaaaa acacacccac
    16201 taaacgagat aaaaccgtcg cccaagcaac accaagaaga ccaaatcccc atacatagat
    16261 agacaaggca gaaaaaatgg cattgagtac gtttattaat aagctcactt gcataggaat
    16321 cttaggatac ccttgagctc gaacaatagc tcctaagcta gttaaaagtc ctagactaac
    16381 aatcataccg ccgacaatgg atagatattg ccctccaacc aatgttacag aagcttcagc
    16441 tcctagccat tctaacacct gatgatgtcc aacaactgat aacaacccta agccgaccga
    16501 aaggaggagt gttacttgca agacacctgc catatagttt aattgtttgt tctgattatt
    16561 ttctccaata cttcgagcaa tcagactaga tacagcagct cccagcgcga taaagaggga
    16621 ctgataaata ctgataatgt tgttagctat ggagacacca gagactgcta aaagtccaat
    16681 ttgagccacc aggtaattat caaccattcc cattaacatc tgtaaaatat tttctatcat
    16741 agaaggcaga gctaaagaga aaatttttct tctattatat atcatttatg tcccctaata
    16801 aaaaattctt gatcaaacga ttttttaaaa cacagtcact ggactcattc agttattttg
    16861 gtccattaat gaattcataa agtctatctt aatagcagag gcccaagata cacgacactt
    16921 agtgttacag taacaattga ccacatgcca atccttaaca tttacctaac gtttataact
    16981 aagaagacga agaacaaaag gactccaaac gaattttttc tattatataa tatattcttc
    17041 atttagcaac tttcaatgta tcaaaatagc actctcgagt caaaaatgtt ttctgatact
    17101 cgagagtgct attttatttg gaaccaagtt taagcaactt aggcttatct catatttaat
    17161 acatttgtat gtttagctga tgaaatctaa gaccttgcgc ccttggatta aaccacgttc
    17221 catttcatca aagacttctg gagcagtgtc aactggaact ttttcgacaa ccggaacaac
    17281 cagaccttct gcaccaaagg caaaggcttc ttccaagtct ttacgtgtcc ctacaagtga
    17341 tccgaccact ttgataccat ctaaaacagt ttttacgata gacagttcca tgtattctga
    17401 tggaagacct acggctacaa ctgttccacc ggcacggaca ctatcaattg cttggttaaa
    17461 agcaacttta gaaacagccg ttaccacaac accatgtgct ccaccggttt tttcttgaat
    17521 atagcctgga acatcttcaa tttctttgcc gttaactaaa atatctgcgc caacttcttt
    17581 agctaactca agtttatcat tattaatgtc cactgcgaca acatgtgcat taaagacttt
    17641 tttagcgtat tgaacagcca gatttccaag gccaccagcc ccaaagataa caatccattg
    17701 gcctggagca gcacctgcct ctttaatagc tttataagtt gttacaccag cacaagtaat
    17761 ggaagaagct tgagccgggt ctaaaccttc tggaacttta actgcataat cagctgttac
    17821 tactgcatat tcactcattc ctccatcaac actgtatcca gcatttttaa cactacgaca
    17881 aagtgtctca cgtcctgtag tacagtattc gcaatgacca catccttcaa agaaccatgc
    17941 aatagagaca cgatcaccaa cctttaagga tgttacgcct tctccaattt cttctactat
    18001 accaatgcct tcgtgcccca aaatacgtcc tggtacctga ccaaaatcgc catgtgcaac
    18061 gtgtaaatca gtatgacaaa cgccacagta ttctacttta acaagcgctt caccatgacc
    18121 aacttttgga agatcatgct caacaacttc gacacctgta ctagcttgat taacaactac
    18181 ggctttcata tcagtcctcc atctaataat gacttatttg taatcggtta caaataaatt
    18241 gtacatcttt tcacaataaa agtcaacaga aacctgaaaa gtttctgaaa cttaaccggt
    18301 taatcttgta gctgtttgcc tatctgcaaa atacttaact acattttctg acactggata
    18361 taaatgatat atttagaaaa taaaatgatt tcttatgact ttaatcataa gaaatcattt
    18421 cctggtatca acattaaaaa tcacttacgt cgtcctggac gttcagcata accatagtaa
    18481 gcatcttcaa taatttcttg catgtgatca accattggaa gacgtgggtt agcaggtgaa
    18541 cattggtctt cataagcaag gtaagccaat tcacgagaat gttctttcca ttcgttttcg
    18601 tcgatacctt gagctttgaa gttcatttga ataccaactc ggcaacccag atcataaaca
    18661 gctttcgcat aagattccac tgcttcttct ggtgtagaag ctggaagccc taacaatttc
    18721 gcaatgtctt ggtatttttc atccgcacgg tagtaattat acttaggcca tgttgctgtt
    18781 ttagctggac gagttccatt atagcggata acatacggca aaagaattgc atttgtacgt
    18841 ccgtgtacgg tatggaattg tgcgccaatt ttatgtgcca ttgagtgaga aatacctaag
    18901 aaagcattgg cgaaagccat acctgccata gttgacgcat tatgcatctt ttcacgtgct
    18961 tcaaaatcgg ctgttttaac tgatttttca agattatcaa aaacaatttt aatggcttga
    19021 agagctaaac catccgtaaa gtcattggcc atttgtgaca cgtaagcttc ggttgcgtgt
    19081 gtcaaaacgt ccataccagt atcagcagca ataaagcctg gaacagtcaa taccaaagct
    19141 ggatcaacaa tggctacagt tggtgttaat gagtaatcag cgattggata tttacgatta
    19201 tttgctttgt cagagataac ggcaaatggt gtcacctctg aacctgttcc agaagttgtt
    19261 ggaatagcaa caaattttgt tttcttacca agttctggga atttgaacgc acgtttgcgg
    19321 atatccatga atttttgaac gaggtcatgg aaatcaactt ctggttgttc ataaaagagc
    19381 cacataactt tggctgcatc cataggagat cccccgccaa gggcaataat ggtgtctggt
    19441 ttgaaggtac gcattaattc agtacctttc ataacagttg taatgtctgg atctggttct
    19501 acttcagcaa agatctgata aacaacttta ttgcgacgaa gatcaagttg ttcaatgata
    19561 cgatccaaga aaccaagctc aaccatagcg tgatctgtaa caatcatgac acgttcaacg
    19621 tcacgacatt tttgcaaata ttgaattgaa tcacgttcga agtatgtttt tgaaggaact
    19681 ttaaaccatt gcatattatt tctacgtctt cctacttttt tgatgttcaa gagatttata
    19741 gcactaacgt tatcaccaac tgcgttacgt ccatacgaac cacaaccaag agtcaatgat
    19801 ggcaagaaag cattgtaaac atccccgata ccaccaaatg tagaaggtga attccagatg
    19861 acgcggatag cacggattct agttccaaat tcttttgcca actctgcatc tgctgtatga
    19921 atggcagctg agtgaccgag tccattaaat tcaaccattt gacgagcttt ttcaacaccg
    19981 tcttcacgtg attcagattt caaaacagca atgactggag ataatttttc acgtgttaaa
    20041 ggctcatttt ctgaaacttc tttacattct gcagcaagaa tattggttcc ttctggaaca
    20101 gtaaatccag cttgttctgc aatccaagta gctggtttcc caacaatgtt tggattcaat
    20161 ttagcgccag cacagttttt actgttagct tttgcaccaa aacagaattc ttcaagaagg
    20221 gctttttctt ttttatttac aaaataagta tggtaagatt tgaactctgc aacaaaatcg
    20281 tcatagattt ctttgtccac gataacagct tgttcagacg cacagaccat accgttatca
    20341 aatgatttag acatcacaat atcatgagcg gcttggcgga tgttagcaga tttttcaaca
    20401 taagctggaa cgttaccagc acctacccca agggcaggtt tcccacatga gtatgccgct
    20461 ttaaccatcg catttccacc tgtcgcaagg atagtggcaa tgccgtcatg attcatcaaa
    20521 gcatttgttg cttcaagtga tggtgtttca acccactgaa cacaattttc aggagcacca
    20581 gcggcgatag cagcgtctct aacaatccga gcggcatgcg ctgatgattc ttgtgctgat
    20641 gggtgaaagg caaaaataat tggattacgt gtttttaacg agatcaaaga tttaaagata
    20701 gctgttgaag ttgggttagt tgttggtgta atcccacaga taacacccac cggctcagca
    20761 attaatgtca aacctgtcac atcatcttct tcaataattc ctactgtttt ttgatggcgc
    20821 atgttattaa ccacatgctc acaagcaaat agattttttg ttgctttatc ttcaaagaca
    20881 ccgcgacctg tttcttcata agcatgttta gcaagttcac cgtgagcatc caaggcagca
    20941 acagaagctt tggctacgat ataatcaact tgttcttggt caagcttacg catctcttca
    21001 agagcagcta aacctttttg aacaagagca ttaattgtca cagaaacaga ggttgtttca
    21061 acagtattat gtccttcagt catttgagac tcctttatct tgttaaaagt ttcacaattt
    21121 tgtttacaaa attattatag cactttttga aattttgtaa atcatttcac aataaatttg
    21181 tgaagttttt ttcaaattat ttctgaaatc ctatggtatc aatattattc attaactctt
    21241 tttcagaaat atatctaaaa aaagccgttt tatttctgaa atcgctttct tttaaaaacc
    21301 tcaaagtact actattttac catcatcatt tgttcacaag aaaaagccag agcacaatgg
    21361 atctgactta tctcttagac atttcttaac tttatttagc tggtttttta gctgacttct
    21421 caacagcagt ctggattgtg gagacatata gttctgctcc ttgactatct tcactataat
    21481 ggacaccgtc actgccatac caaatatctg gatgtccaac agcaacttta taccagtctg
    21541 caatagtgac atacttgtat tttttggaca atttaagacc atagtctcta gcttctgcaa
    21601 cctgactggc atttttggca ttatatggag aaaccaaaac taaacgatgt ccttttggca
    21661 atgcctcaat aaaagactga actgcttgag aatagttgtc aagcgagtta acacctactg
    21721 ctaagacaac agtcttagat agactcttag acttaatttg gttattaaat aaatcgaaag
    21781 cttctttaaa attccgactg accgctgcat ccagttgcgc ttgtggcata atttttgaga
    21841 atgccgcact agagcgtaat gctacagaat caccaataat acctacgtca ctcaaagcat
    21901 tagcgtctcc tgcagctagt gtatgtgtcc gctccatatt actttgagcc tgttgtaggg
    21961 aactaaccaa caattgtttc tcaaacttac caactttagg cgctatcata caagttccta
    22021 aagttaataa tgctaaggcg agagtccctc ctacaatcca cttatagtaa ggagaacagt
    22081 caatttctaa accaagcagg tttggttttc tcccttggac caaaggttcc acaatatagt
    22141 aagacacagt ggcaaacaag attgaaaaga aaactgttag aataactgcc aaaatatgag
    22201 acattaattg gctaaaaata atgtaaaatg gccaatggaa gaggtaaatc ccatagctaa
    22261 tatcagctat ataagtgata gctttaggct cttgtacatc tggtgtttgc tcatgaagaa
    22321 cacgcgctgc ataaatcata attgatgcga ataggctagc caaagcaaag ccaaatagat
    22381 aggtcgtaat atggttaaaa tccaatgtga ccgttagcac aagcaaaagt gtaaatgctc
    22441 caaccatagc agcaaggaca tactggcgcg gccataaacg tacatttttt tgaaatcgaa
    22501 cagtagtctc gttaatacct gttatcgtgg caaacatcgc ccctaaaaag aagggaaaac
    22561 tgtgagaaag actcgaaaaa taaatcaggg aaaaatttga ggtcataaaa gatcttataa
    22621 acatgctcaa gaaactaata gcaaatattc ccaaagaaat caaaaacagt agtcctctca
    22681 gttgtttctg agtctccttg cgtctagcta ataaccaaac aaatacaccc cacaacaagt
    22741 aaaaatgaac ttcaatagct aagctccacg tatgaacaaa gagatgtgga ataaattggc
    22801 tttcataact acttcccgtc aatatttcat aaatattagt ggtaaatcct aaaacagctg
    22861 taatctgact tcctatatta gcaatgaaat ccttcttaat taaaaacgta aaaggaatgg
    22921 tcaataaaat cattaacacc aaaggaggaa caattcgata aaagcgtctt tttaaaaaac
    22981 cgataatatc gatagactct ttttttgtgt attcatcaat caagagggct gtgattagat
    23041 atcctgaaaa ggtgaagaaa atatcaacac caataaaacc tcctggaaat acatttttaa
    23101 aaaagtggta gagtaaaacc agtaaaagtc ctgttaccct aacaaacgaa aaccatttta
    23161 ttctcatttt tgaaatatcc cctgtttaaa aatcccttta tagactttat tattctttgc
    23221 ttttaacaca cctttgccat ttgcttgtcc tttatgaaac tccccgttat ataaccagcc
    23281 cgtcttagca gtaaaagttc cttttccttc aaataggcca ttcttaaaag taccctcata
    23341 gatatcaccg ttggggtaga caagcttccc ttctccattc attttatggt taatcacgta
    23401 accagtatag tgcatacgcc ctttatcata ggtcaaactt gtcttattcg aaattcttac
    23461 gctaaaaaca gaaattgcac aaaccaatat gacaatcacc gagacaattt ccaacttcgc
    23521 ccgtgtaata ctccattttt ttactatatc ttgcatatct atcatttctt ttactcaact
    23581 tctaatatca atactcttta ctcattaaac gagaaagcca atcctggcat ccttttctaa
    23641 ctaattggta ggtttcttca aaatcgttag tgtaccaagg atcaggaaca cccccttctc
    23701 taaacaggta gattttagag tcccattgat gttgcgacat ctctttgaga tttttcacat
    23761 tatcgctatc cataccaata atatagtcaa aggtgttaaa atcagttata gttatctgct
    23821 tggagcattt agttatatca tagttaattt ggtaagtttt taatatggac tgtgtacctg
    23881 agtgaatagg gtttccatgc tcccaatcag aagtagcacg actttctatc atcataacat
    23941 cacttgatac tattgacttc attacaaact cagccatggg gcttcgacaa atattaccca
    24001 gacagacaaa acatactttt ttcattaaat actcctttga attattatat caaatttcta
    24061 actgatatcg gagaaatcaa tctaataatt ttctgtcaac ttatcaaaaa atccgaacac
    24121 aaaaagcagg ttcagattaa ttttcttaga tttgaaaaat cattaagtgt tttgataggg
    24181 atagccaaga tgacgataag ccttttgcgt cgctacacga cctgttcgtg ttcgcatgag
    24241 aaagcctttt tgaattaagt agggttcata cacctcttca actgtattac gctcctcggc
    24301 aatattcaca gataatgtcc ccaaaccaac tggtcctccc tgatacatct caatcatcgt
    24361 tcgtaaaatt ttctgatcaa tgtaatcgag accttcgcgg tcaacatcta acatagtcaa
    24421 agctctatca gttatttgag ccgttatgat gccatcacca ataatttgag cataatcacg
    24481 cactcgtttt agtaatcgat tagcaatgcg gggcgttcct ctactgcgac aagctaattt
    24541 ccgtgcagct tcatggtcta tttttatttc aaaaatagta gctgtacgct ccacaatctc
    24601 tgtcaaatcc ttttcttgat agtattccat gtgaccagtg ataccaaaac gagctctgag
    24661 gggattagat aacatgcctg cacgtgtagt agcaccaatc aatgtaaatg gaggcagatc
    24721 caaatgaata ctacgactag tatctccagc gccaatcata atatcaatat agaagtcttc
    24781 catagcacta tatagtactt cctcgacaga cattggcatg cggtgaattt catcaataaa
    24841 caaaatatcc cctggttcta attcatttaa aatagctacc aaatctccag ctttctcaac
    24901 ggcaggacct gaagtttgct ttaaattaac tcccaattca ttggcaatca caaatgccat
    24961 tgttgttttt cccagtcctg gaggtccaaa taataaaaca tggtctaaag attcgtcacg
    25021 tcttttagct gcttctataa aaatagcgaa ttgttcctta actttatctt gtccaatata
    25081 ttcgtgtaga tattgagggc gaagagtccg atccgaaaac tcctcatttc ccattacatt
    25141 attgtctaaa attctagcca taggactatt ataacataaa gtaaaagaga gcagtggcct
    25201 acttttatta taatcgccac cagtcaacag cactaagctc ttgaactact ttaaaagata
    25261 gtagagctgc gaatataaaa tagtact
//
LOCUS       DATTYN010000028        25220 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.28, whole genome shotgun sequence.
ACCESSION   DATTYN010000028 DATTYN010000000
VERSION     DATTYN010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25220
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.28"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            204..365
                     /gene="sagA"
                     /locus_tag="VB649_001407"
     CDS             204..365
                     /gene="sagA"
                     /locus_tag="VB649_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOMM family cytolysin streptolysin S"
                     /protein_id="HEP1670355.1"
                     /translation="MLKFTSNILATSVAETTQVAPGGCCCCCTTCCFSIATGSGNSQG
                     GSGSYTPGK"
     gene            587..1537
                     /gene="sagB"
                     /locus_tag="VB649_001408"
     CDS             587..1537
                     /gene="sagB"
                     /locus_tag="VB649_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S biosynthesis dehydrogenase SagB"
                     /protein_id="HEP1670356.1"
                     /translation="MSFFTKEKQPKENCPPITVEKARQLFEFNTNHLSLSDYHHQTVL
                     KTSKQLVAQHLMPNATDNLSQHFLMNYKANNNYLGFQASIVDFFTDSAVANFSSSYVY
                     ESQEKIIRLPKPTKISTALSTCIIKRRSHRQFSDRQMPLQDLSNILYYACGVSSQASI
                     RDGASDKITLRNCASGGGLYPIHLVFYARNISKLIDGFYEYLPYQHALRCYRHSSEEN
                     VRDFAEYGAINAENCNIIIIYVYHYMKNTRKYGNQATAYAFIESGEIAQNIQLTATAL
                     TYGSIDIGGYNKEYLQELLDLDGLGEHVIHMTLVGTKESQ"
     gene            1534..2592
                     /locus_tag="VB649_001409"
     CDS             1534..2592
                     /locus_tag="VB649_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEP1670357.1"
                     /translation="MKYQLNSNVRVVTFQDTFCFRKGIWDFNEAILDLTQEPQNLKIV
                     YQEIVSQLVKGVAIDTETYENTLEPETFANLMEVISGLYYNDMLMLEDDYNLEENVMK
                     ILMGNFRFMAQAGHMVSNAPVLFISDSTYVNESAELLAEQLHLQLQVASDDLKMLIQQ
                     TDVSSRLDALEHRRNMNCLSEALCDYQSIIICQERLNIMMLRHLNEVSVAMKKQLVIG
                     FVDGPFLHTCTLNPPHSADFDSLERRVLARLQDSTLYQHFANQILPATQDVSQAYLPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSIYLPTLEIQVQDILKMSNSQTQGALAKLK
                     YEDQQISTREIVKKLLDE"
     gene            2612..3970
                     /locus_tag="VB649_001410"
     CDS             2612..3970
                     /locus_tag="VB649_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEP1670358.1"
                     /translation="MLYYYPSFNHIFDELKSLSGNRTGILNQSQVPVCNHPHDVYLKS
                     ITGQMPDYHKQFIGELSQVSYHIIGYGSYYEEALIKYLGESIERYATVIAGDLLSDRI
                     VYASYNELKLLHKVMPLEYLQVFTQEQIALSCDLQMMMCDKMVTENDVLGWVRCPMFF
                     EDAEMYVPAQMLCVGYKTNETVGERRIIPGFSTGTASHKTLEAAMCNSLIEYIQIDSM
                     MLSWYTKKPCPKIIVDDPDIEVILEEARLGKDSLYDIIPIDMTVGEDNPLYTFGIILK
                     NKYDEGPYLLFGVQAGLDPKHALLRGIMEASAISYSYYYNLLYQKASLANIECEEPLF
                     LDLDSNVFYYAHPKDQDHKWKAFEPLISGEVLLSDLEDHSGKDKKEDLKTLLAYAKKV
                     SPNAVFLDITPPEALEKGWYVTRVLMPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            3945..4616
                     /locus_tag="VB649_001411"
     CDS             3945..4616
                     /locus_tag="VB649_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEP1670359.1"
                     /translation="MPLSIQCLNLCFLLVTFCPSIPMQAIFGKEDSGYAFNLIGFLRA
                     TLIYDILALVSIYVLSPQITLSLESIDSKTFFMGLVFCVLIVLIELVFLHGLRCWQKK
                     QWLPATFSFVGTTNDWSKIGYPLLLALFEETIYRFLWFNILAFQWHLPTIIVLIVTSF
                     CYALNHLLMGKSIFYAKLVTGIIYGSIYMLTSQLWLVVIMHVGGNLLVECLSHLQTKK
                     KKEVT"
     gene            4613..5296
                     /locus_tag="VB649_001412"
     CDS             4613..5296
                     /locus_tag="VB649_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEP1670360.1"
                     /translation="MMLLVLLSFLGLTTLWLTSYRRRCLARWHLQWLMALSYQDFLDV
                     LLSLFQFVVIILVLFFYSATINLGEVLTFLTQTSWHWQILCYLVLYLMAVIEMTLLVL
                     ILIFDVLLQKDSRLLFKKITWLPFRQDKPVLSILLLGIVILVDSLFYLGLLILLGEQS
                     LTSLATLILGYGIVKACRYSGWLNVLLAFCLFTIVGLWAVTATLLYGWLVGVMILTVT
                     YLMISCKEY"
     gene            5319..6242
                     /locus_tag="VB649_001413"
     CDS             5319..6242
                     /locus_tag="VB649_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670361.1"
                     /translation="MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKS
                     TLINLILGLIPLSSGKITVLGQSQKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGAQLKKQVLKSLEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPK
                     FELEKRYVANLANQIIVTLTDSRHLELADKPDWSLIEDGEKLMLKIDNSDMTSVVHQL
                     TQANITFSEIRHNHLNLEEIFLHLTGKKLRD"
     gene            6251..7378
                     /locus_tag="VB649_001414"
     CDS             6251..7378
                     /locus_tag="VB649_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670362.1"
                     /translation="MVLFHLIKKESLQIFRNRTALLMMVIFPILMIVILSFAFKSSFN
                     TATTVPKLTIRYQLEGEKTDYQKNFLAFLKVLNQKLHLEAKPSNSLEKDRQRVSEGAL
                     TAVLEVKKNQTIKVITNNINQQNADLINMLVKNYVDNAKTYDSIAALYPQQLNHIRKR
                     SVDYVKVSSIQTSKGMTSADYYAISMFTMITFYSMMSAMNLVLSDRQQRITNRIHLTG
                     VSPSLLVFGKLIGAMLATTVQLSLLYIFTRFVLRVNWGTNEWMLIGITASLVYLSVAI
                     GIGLGISIKNEAFLTVASNTIIPIFAFLGGSYVPLTTLHSSIINQLSNISPIKWVNDS
                     LFYLIFGGQYNPIPVTLIVNISIGTIFIILSLIGMRKQVTT"
     gene            7375..8493
                     /locus_tag="VB649_001415"
     CDS             7375..8493
                     /locus_tag="VB649_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670363.1"
                     /translation="MICFIKTLFVKIKRKKTSYVTFFLMPILTTLLALSLSFSNNNQA
                     KIGILDKDNSQISKQFIAQLKQNKKYDIFTKIKKEHIDHYLQDKSLEAVLTIDKGFSD
                     KVLQGKSQKLNIRSIANSEITEWVKAQTNYLLENYNIIGDVALGNEDTFNRILQKNQQ
                     LNYDVKQVTLTDRSRSKAVSSTTTGFLLILMLGSTSVIYSGILADKSSQLYHRLMLSN
                     LSRFRYMVSYVCVGFVAFTIQIVIMLSLLKVFNISFFVPTSLLLIIFFLFSLLAIGFG
                     LLIGAITQNSQQSSQLANLIVMPTSMLAGCLWPLSITPSYMQAIGKLLPQNWVLSAIA
                     IFQSGGTLSQAWPYLLALMGTALALIIFSSLLLKPTRL"
     gene            9064..11796
                     /locus_tag="VB649_001416"
     CDS             9064..11796
                     /locus_tag="VB649_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnA family nuclease"
                     /protein_id="HEP1670364.1"
                     /translation="MINKKCIISVSLLTLAITLTSVEEVTSRQNLTYANEIVTQRPKR
                     ESVISDKSNFPVISPYLASVDFGERKTPLPTPDKGVKVTTEQSIAQVRKGPEERTYTV
                     TGKITSVINGWGGYGFYIQDSEGIGLYVYPQKDLGYSKGDIVQLTGTLTRFKGDLQLQ
                     QVTAHKKLELSFPTSVKEAVISELETPTPSTLVKLSHVTVGELSTDQYNNTSFLVRDD
                     SGKSIVVHIDHRTGVKGADVVTKISQGDLINLTAILSIVDGQLQLRPFSLEQLEVVKK
                     VTSSNSDASSRNIVKIGEIQGASHTSPLLKKAVTVEQVVVTYLDDSTHFYVQDLNGDG
                     DLATSDGIRVFAKNAKVQVGDVLTISGEVEEFFGRGYEERKQTDLTITQIVAKAVTKT
                     GTAQVPSPLVLGKDRIAPANIIDNDGLRVFDPEEDAIDYWESMEGMLVAVDDAKILGP
                     MKNKEIYVLPGSSTRPLNNSGGVLLPANSYNTDVIPVLFKKGKQIIKAGDSYKGRLAG
                     PVSYSYGNYKVFVDDSKNMPSLMDGHLKPEKTNLQKDLSKLSIASYNIENFSANPSST
                     KDEKVKRIAESFIHDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLIDAIKKLGGP
                     TYRYVDIAPENNVDGGQPGGNIRTGFLYQPERVSLSDKPKGGARDALTWVNGELNLSV
                     GRIDPTNAAWKDVRKSLAAEFIFQGRKVVVVANHLNSKRGDNALYGRVQPVTFKSEQR
                     RHVLANMLAQFAKEGAKHQANIVMLGDFNDFEFTKTIQLIEEGDMVNLVSRHDISDRY
                     SYFHQGNNQTLDNILVSRHLLDHYEFDMVHVNSPFMEAHGRASDHDPLLLQLSFSKEN
                     DKAESSKQSVKAKKTSKGKLLPKTGDSLVYVITLLGTASLLVPILLLTKGKKES"
     regulatory      11961..12076
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            12074..12574
                     /locus_tag="VB649_001417"
     CDS             12074..12574
                     /locus_tag="VB649_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEP1670365.1"
                     /translation="MTKLTVHDYVHIGLVAALYVVLTITPPLNAISYGMYQFRISEMM
                     NFLAFYHRKYIIAVTLGCMIANFYSFGLIDVFVGGGSTLIFVTLGVILFSKYQKDYLF
                     NGIFNKAFVYFSFFFATSMFTVAIELYFFGAPFLLTWFTTALGELVSLLIGSLIIDKL
                     SQRISF"
     gene            12768..14726
                     /gene="ligA"
                     /locus_tag="VB649_001418"
     CDS             12768..14726
                     /gene="ligA"
                     /locus_tag="VB649_001418"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEP1670366.1"
                     /translation="MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQ
                     SYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNA
                     TYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTIT
                     VRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTAVVAKRELATFLYQE
                     ASPTAINQQNEVLAELADLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVV
                     IKVNSLAMQEELGVTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIP
                     KLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFL
                     AGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGS
                     KVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAG
                     VNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVI
                     AGSDAGSKLEKAKSLGIRIEDEDWLRQL"
     gene            14740..15762
                     /locus_tag="VB649_001419"
     CDS             14740..15762
                     /locus_tag="VB649_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEP1670367.1"
                     /translation="MKKQLRARLIYNPTSGQELMRKSVPEVLDILEGFGYETSAFQTT
                     AQKNSALNEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLKKRPKMAIIPTGTTNDFA
                     RALKVPRGNPSQAAKLIGKNQTIQMDIGRAKKDTYFINIAAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDKGVFEGQVSMIFAAITNSVGGFEMIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLILDGGKHITDRRVEYIKTSKIVIEPQCGKRMMI
                     NLDGEYGGDAPITLENLKNHITFFADTDLISDDALVLDQDELEIEEIAKKFAHEVEDL
                     EQELEE"
     gene            16154..16351
                     /locus_tag="VB649_001420"
     CDS             16154..16351
                     /locus_tag="VB649_001420"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEP1670368.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKAASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            16386..17102
                     /gene="atpB"
                     /locus_tag="VB649_001421"
     CDS             16386..17102
                     /gene="atpB"
                     /locus_tag="VB649_001421"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEP1670369.1"
                     /translation="MEEAKIPMLKLGPITFNLTLLAVCIVTIAVIFAFVFWASRQMKL
                     KPEGKQTALEYLISFVDGIGEEHLDHNLQKSYSLLLFTIFLFVAVANNLGLFTKLETV
                     NGYNLWTSPTANLAFDLALSLFITLMVHIEGVRRRGLVAHLKRLATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRVYWWPIAFLVNMAWTAFSVFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            17120..17614
                     /gene="atpF"
                     /locus_tag="VB649_001422"
     CDS             17120..17614
                     /gene="atpF"
                     /locus_tag="VB649_001422"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEP1670370.1"
                     /translation="MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQ
                     ISRDIDQAEQSRLSAQQLEAKSQANLDASRLQASKIISDAKEIGQLQGDKLVAEATDE
                     AKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDD
                     LGEA"
     gene            17614..18150
                     /locus_tag="VB649_001423"
     CDS             17614..18150
                     /locus_tag="VB649_001423"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEP1670371.1"
                     /translation="MTKKEQALIEQYAKSLVEVASEHHSLDTLQADVLAILETFVTTN
                     LDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIA
                     IVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            18166..19674
                     /locus_tag="VB649_001424"
     CDS             18166..19674
                     /locus_tag="VB649_001424"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEP1670372.1"
                     /translation="MAINAQEISTLIKKQIENFQPNFDVTETGIVTYIGDGIARARGL
                     DNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS"
     gene            19690..20565
                     /locus_tag="VB649_001425"
     CDS             19690..20565
                     /locus_tag="VB649_001425"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEP1670373.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVRSEQAARDFQ
                     IYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSV
                     MDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVD
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRHDI
                     LDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            20727..22133
                     /gene="atpD"
                     /locus_tag="VB649_001426"
     CDS             20727..22133
                     /gene="atpD"
                     /locus_tag="VB649_001426"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEP1670374.1"
                     /translation="MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDHLPEDAF
                     RSVGPIEDVIKKAEKMGF"
     gene            22146..22562
                     /locus_tag="VB649_001427"
     CDS             22146..22562
                     /locus_tag="VB649_001427"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEP1670375.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAP
                     LQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK"
     gene            22828..23085
                     /locus_tag="VB649_001428"
     CDS             22828..23085
                     /locus_tag="VB649_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEP1670376.1"
                     /translation="MVCYNNPMELLMKIIAFSCHLFFIGLSYQLLISVIDWTKFSHYH
                     PENLGRLRLFVFLLATALGYLVSHCMLELLQISQTLFFEFR"
     gene            23150..24421
                     /gene="murA"
                     /locus_tag="VB649_001429"
     CDS             23150..24421
                     /gene="murA"
                     /locus_tag="VB649_001429"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEP1670377.1"
                     /translation="MDKIIIEGGQTRLEGEVVIEGAKNAVLPLLAASILPSKGKTILR
                     NVPILSDVFTMNNVVRGLDIRVDFNEAANEITVDASGHILDEAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPINLHLKGLEAMGATITQKGGDITAQADRLQGAMI
                     YMDFPSVGATQNLMMAATLADGVTTIENAAREPEIVDLAQFLNKMGARIRGAGTETLT
                     ITGVTHLRGVEHDVVQDRIEAGTFMVAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VTEEEYGIRVQANTPKLKPVTVKTLPHPGFPTDMQAQFTALMAVVNGESTMVETVFEN
                     RFQHLEEMRRMGLQSEILRETAMIHGGRQLQGAPVMSTDLRASAALILTGIVAQGVTI
                     VNNLVHLDRGYYQFHEKLAKLGATISRSSEV"
     gene            24425..24613
                     /locus_tag="VB649_001430"
     CDS             24425..24613
                     /locus_tag="VB649_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEP1670378.1"
                     /translation="MTNGLKYVLEQMLLLLVIAALACLFLAIGLMIGYSFMGDGHSPW
                     HILSMDKWAELVNKFTGK"
     gene            24649..25186
                     /locus_tag="VB649_001431"
                     /pseudo
     CDS             24649..25186
                     /locus_tag="VB649_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
BASE COUNT         7831 a         4174 c         5166 g         8049 t
ORIGIN      
        1 tttgataata ttaaaaagaa agggtttaca tattaatcat tttttactat aataaaagtg
       61 ataagaacta gatagttgtt gtgttacaat ggtacaattg agctagcctt gtccttgttg
      121 tgttaacttt atttttaaaa taaggttaaa aataaacgac tcgtgttctt atcagttact
      181 tattagataa ggaggtaaac cttatgttaa aatttacttc aaatatttta gctactagtg
      241 tagctgaaac aactcaagtt gctcctggag gctgctgttg ctgctgtact acttgttgct
      301 tctcaattgc tactggaagt ggtaattctc aaggtggtag cggaagttat acgccaggta
      361 aataatctat ttagcatctc tatgtgatag tgatattagg gtaatgagtt tgctagcaac
      421 taagttatct ttggtaactt ctgattatag atgaatggca tagaggtgtt agaaaacatg
      481 agacaaaagt aatcttcttg atgctaacgt ctcaggtaat tagcaggtac tagacagtac
      541 ctgctaatta ctatatgttt agtaaaatga gataggaaag atagttatgt cattttttac
      601 aaaggaaaaa caacctaaag agaattgtcc gccaataact gttgaaaaag caaggcaatt
      661 gtttgaattt aatacaaacc acttgtcctt atcggattac catcatcaaa cggtgctaaa
      721 aacgtcaaag cagctagttg ctcaacattt aatgcctaat gcaaccgata atcttagtca
      781 acattttttg atgaactata aagctaataa taattattta ggcttccaag ctagtattgt
      841 cgactttttt acagattctg ccgttgctaa tttttcaagt agttacgttt atgaaagtca
      901 ggaaaagata attcgtttac caaaacctac caagatatca actgctctgt cgacatgtat
      961 tataaaacga agaagtcatc gtcaattttc agatagacaa atgcctcttc aagatttatc
     1021 aaacattctt tattatgcat gtggtgttag ttcacaagca tcaattagag atggagcatc
     1081 agataagatt acactcagaa actgtgcttc aggtggaggt ttatacccta ttcatttagt
     1141 tttttatgct agaaacatca gtaaattaat agatggtttc tatgaatatc taccctatca
     1201 gcatgcacta aggtgttatc ggcatagctc tgaggaaaac gttagagatt ttgcggaata
     1261 cggtgctatt aatgctgaaa attgtaatat tattattatt tatgtctacc attacatgaa
     1321 aaatacacgt aaatatggga atcaggcgac tgcctatgct tttattgaat caggagaaat
     1381 agcccagaat attcaattga ctgcaactgc cttaacttat ggaagtattg atattggtgg
     1441 ttataataag gaatatctcc aagaattatt agatttagat gggctaggag agcatgtgat
     1501 tcacatgaca ctcgtaggaa ctaaggagtc tcaatgaaat atcaacttaa tagtaatgtt
     1561 cgtgtcgtga catttcaaga tacattttgt tttagaaaag gaatctggga ctttaatgaa
     1621 gccattctag atttgacaca agaacctcaa aatttaaaga tagtttatca agaaatagtt
     1681 tcacagttgg ttaagggagt agccattgat actgaaactt atgaaaatac tttagaacct
     1741 gagacgttcg ctaatttaat ggaagtcatt tcaggcttgt attacaatga tatgctgatg
     1801 cttgaggatg actacaatct tgaagaaaat gtcatgaaaa ttttaatggg taatttccgt
     1861 tttatggcgc aagcaggtca tatggtaagc aatgctcctg ttttgtttat cagtgattcg
     1921 acttatgtta atgaatctgc tgagttgcta gctgaacaac tgcatttaca attgcaagtg
     1981 gctagcgatg acttaaaaat gttaattcag cagacagatg ttagttcgcg tttagatgct
     2041 ttggagcatc gccgtaacat gaattgttta tcagaagcct tgtgcgatta ccaaagtatt
     2101 attatttgtc aagaacgctt gaatattatg atgttgcgac acttgaatga agttagcgta
     2161 gctatgaaaa aacaattagt gattggtttt gtagatggac cattcttgca cacttgtact
     2221 ttgaatcctc ctcatagtgc tgactttgat agcttagaaa gaagagtttt ggcacgttta
     2281 caagactcaa ctctctatca acattttgct aatcagattt taccagcaac acaagatgtg
     2341 agccaggcct atttaccatt gttaaatgtt ttaatgaatt tagtcgttag cgaagctttc
     2401 attattgctc aaacaggtag ttctaaattt gagggacgtt tattaagcat ttacttaccg
     2461 acgcttgaga ttcaggtcca agatattttg aaaatgtcta attcacagac acaaggagct
     2521 ttggcaaaat taaagtatga ggatcagcag atatcaacac gtgagattgt taaaaaactc
     2581 cttgacgagt aacctataag gagaatctat tatgttatac tattatcctt cttttaatca
     2641 tatttttgat gaattaaaaa gtttaagtgg caatcgaaca ggtatcttaa atcaatctca
     2701 agttccagtt tgcaaccatc ctcacgatgt ttacttaaaa agtattactg gccaaatgcc
     2761 agattatcat aaacaattta taggtgagtt gagtcaagtt agttatcaca ttattggtta
     2821 cggcagttac tatgaagaag cacttatcaa gtatttagga gaaagtattg aacgctatgc
     2881 tactgtaatt gccggagact tactatcaga tcggattgtc tatgcttctt ataatgagtt
     2941 aaaactgtta cataaagtga tgcctttaga atacttgcaa gtgtttactc aagaacagat
     3001 cgcattatct tgtgacttgc aaatgatgat gtgcgataaa atggtaactg agaacgatgt
     3061 attgggctgg gttagatgtc ccatgttctt tgaggacgca gagatgtatg ttccagctca
     3121 aatgctttgt gttgggtata aaacaaatga gactgtagga gaaagacgga taataccagg
     3181 attttctacg ggaacagctt ctcacaaaac gttagaagcg gctatgtgca acagtttgat
     3241 tgaatacatc cagatcgatt caatgatgct tagctggtat actaagaagc cttgccccaa
     3301 gattattgtt gatgatcctg atattgaagt gattttagaa gaagctagac tgggaaaaga
     3361 cagtctatac gacattattc ctatcgatat gactgtagga gaagataatc ctctttatac
     3421 gtttggaatc attctcaaaa ataaatatga tgaagggcct tacctcttgt ttggagtgca
     3481 ggctgggtta gatcctaaac atgctttgct aagagggatc atggaagctt cagctattag
     3541 ctatagttac tactataatc ttttatatca aaaagcttcc cttgcaaata ttgaatgcga
     3601 agaacctttg tttttagatt tagatagtaa tgttttctat tatgcacatc ccaaggacca
     3661 agaccataaa tggaaggcct ttgaaccttt gatttcagga gaagttctgt taagtgattt
     3721 ggaagatcat tctggtaaag ataaaaaaga agatttgaag actttattag cttatgctaa
     3781 gaaagtcagt cctaatgctg tctttttaga tattacacct cctgaagctc tagaaaaagg
     3841 ctggtacgtc acgcgagttc tgatgccaga acttcttgaa atgtgtatac cagcatttcc
     3901 ttttgctaat catccacgaa tgagacagtt tggaggtgta acaaatgcct ttgtccatcc
     3961 aatgccttaa tctttgtttt ttgttggtaa ctttttgtcc ttcaattcct atgcaagcta
     4021 tttttggaaa agaagatagt ggttatgcat ttaatttaat tggttttcta agagcaactc
     4081 tgatttatga cattttggct ttggtaagta tttatgtttt gtcacctcaa ataaccttgt
     4141 ctcttgaaag tattgatagt aagacgttct ttatgggact tgtattttgc gtcttgatag
     4201 tactgattga actcgttttc ttacatggtt tacgttgttg gcaaaaaaag caatggcttc
     4261 ctgcaacttt ctcgtttgta ggaacgacaa atgattggtc taagattggc tatcctttat
     4321 tactagcttt atttgaagag acgatttatc gttttttgtg gtttaatata ttagcttttc
     4381 aatggcattt accaacaatt attgttttaa ttgtaactag tttttgctat gctttaaatc
     4441 acttattgat ggggaaatcc attttttatg ctaagttggt aacaggtatc atttatggta
     4501 gtatttacat gctgactagt caattgtggt tggttgtgat aatgcatgta ggaggtaact
     4561 tgctagttga gtgtcttagc catcttcaaa caaaaaagaa gaaggaggtg acatgatgct
     4621 attggttttg ctgtcgtttt taggtctaac tactctttgg ttgaccagtt atcgaagacg
     4681 gtgtttggct agatggcatc ttcaatggtt aatggcctta tcctatcaag attttttaga
     4741 tgtcttactg agtctgtttc aatttgtcgt tattatactt gttttgttct tttactcagc
     4801 tactattaat ctaggagagg ttctgacctt tttgacacaa actagctggc attggcagat
     4861 tctttgttat ttagtgttat atcttatggc cgtcatagag atgacgcttt tagttttaat
     4921 tcttatcttt gatgttttgc tccagaaaga cagtcgattg ctctttaaaa aaataacttg
     4981 gctgcctttt agacaagata aaccagtctt aagtatactt ttactaggca tagttattct
     5041 agtagacagt ctcttttatt tgggcttgct tatattatta ggagaacagt cgctaacaag
     5101 tttagcaacg cttattttag gttatgggat agtcaaggct tgtcgctatt caggttggtt
     5161 aaatgtacta ttagcttttt gtcttttcac tatagttgga ctatgggcag ttacggctac
     5221 tttattatat ggttggctag taggtgtgat gatattaacg gtgacttatt tgatgattag
     5281 ttgcaaagag tattagcaat attaaaaagg agtgatatat gagttttgta caattaacaa
     5341 atgttgtaaa gtcctacaaa aacggcaaga aagctgtcaa tgatgtttcc ttgtctattg
     5401 aagcaggtaa tatttatggt ctgttaggac caaatggtgc tggtaagtct accttgatta
     5461 atcttatctt aggcttgatc cctttgagtt ccggtaaaat tactgtttta gggcaatccc
     5521 aaaagactat tcgaaaaata agttcgcaga taggttatgt tcctcaagac attgctgttt
     5581 atccagacct aactgcttat gaaaatgtag aactatttgg gtcactttat ggcttaaagg
     5641 gagctcagct taaaaaacaa gttctaaaaa gtttagaatt tgtggggcta cactcccaag
     5701 ctaagcagtt tccaagtcaa ttctcaggag gaatgaagag acggttaaat atcgcttgtg
     5761 cgctagttca ttcacctaaa ttaatcattt ttgacgaacc gactgtaggg attgatcctc
     5821 aatcacgtaa tcatatttta gagtcgattc gtttgctaaa caaagaaggt gccacagtta
     5881 tttatacgac ccattacatg gaagaagtag aggctctttg tgattatatt tttattatgg
     5941 atcatggtca agttattgaa gaaggaccta aatttgaact ggaaaaacgt tacgttgcaa
     6001 atctagcaaa ccagattatt gtaactctaa cagattcacg tcatttggaa ctggcagata
     6061 agcctgattg gtctttgata gaagatggag aaaaactcat gttgaagatt gataatagtg
     6121 atatgacatc agttgttcat cagctcacac aggccaatat tacttttagc gagattagac
     6181 ataaccattt gaatttagaa gaaattttct tacacttaac aggtaagaag ttacgagatt
     6241 agaggttact atggttttat ttcatttaat caaaaaagaa agtttacaga tttttagaaa
     6301 ccgaacagcc ttattgatga tggtgatttt tccaattttg atgatcgtta ttttaagttt
     6361 tgcctttaaa tcaagtttta atactgcgac aacagtccct aaattgacca ttcgttacca
     6421 attagagggt gaaaaaacgg attaccagaa aaattttctt gcttttttaa aagttttaaa
     6481 ccaaaaactt catttagagg ctaaacctag taattctctt gaaaaagatc gacaaagggt
     6541 cagtgaagga gccttaacgg ctgttttaga agtgaagaag aatcagacca ttaaggttat
     6601 tactaataat attaatcagc aaaatgcaga tttgatcaat atgctagtaa aaaattatgt
     6661 agataatgct aaaacttatg actcgatagc agctctttat cctcaacaat taaatcatat
     6721 cagaaagcga agtgtggact atgttaaggt cagttcaata cagacaagta aaggaatgac
     6781 atcagctgat tattatgcta tttccatgtt taccatgatt actttttata gtatgatgtc
     6841 tgcgatgaac cttgttttgt cagatcgtca acaacggatt acaaatcgta ttcacttaac
     6901 aggagtttct ccaagtcttt tggtctttgg gaaattaata ggtgctatgt tagcaacaac
     6961 tgttcaattg agtcttttat acatttttac aaggtttgtt ttacgagtta attggggcac
     7021 taatgagtgg atgcttattg gtataacagc ctccttagtc tatctctctg tagctatagg
     7081 tatcgggcta ggtataagca ttaaaaatga ggctttttta acggttgcat ccaatactat
     7141 tattcctata ttcgcctttt taggaggcag ttacgttcca ttgacaacat tacacagctc
     7201 tattattaat caattgtcga atatatctcc tattaaatgg gttaatgata gtttgttcta
     7261 tcttattttt ggtggtcaat ataatccgat tcctgtaact ttgatcgtta atattagtat
     7321 cggaacaatt tttataatat tgtcattgat aggtatgaga aagcaggtga cgacatgatt
     7381 tgttttataa aaactctatt tgttaagata aagcgcaaaa aaacaagtta tgtgacattc
     7441 tttttaatgc ctattttaac gacacttttg gctttatctt tgagtttttc aaataataat
     7501 caagctaaaa ttgggatatt agataaagat aatagtcaga tatctaaaca atttattgct
     7561 caactaaagc aaaacaaaaa gtacgacatt tttaccaaaa tcaaaaaaga gcatattgat
     7621 cactaccttc aagataaatc tctagaagcg gtattgacta ttgacaaagg gttctcagat
     7681 aaagtgttgc aaggaaaatc tcaaaaactc aatatacgtt cgattgctaa tagcgaaatt
     7741 acagagtggg taaaggcaca gaccaattat ctattggaaa attataatat tataggggat
     7801 gtggctctag gtaacgaaga tacttttaat agaattctcc aaaaaaacca acagttaaat
     7861 tatgatgtta agcaagtaac tttgacagac cgatcacgta gcaaagcagt atcttccaca
     7921 acgacaggat ttttgcttat tctaatgtta ggtagtacga gcgtgattta cagtggtatt
     7981 ttggcagata aatctagtca gttataccat cgattaatgt tatcgaactt atctcgtttt
     8041 cgctatatgg tgagttacgt ctgtgtagga tttgttgctt ttacgattca aattgtcatt
     8101 atgctgagtt tgttaaaagt atttaatatt agtttttttg ttccgacatc acttcttttg
     8161 attatttttt tcctttttag tttattagcg ataggctttg gcctgctgat tggagctatc
     8221 acacaaaatt cccaacaaag tagccagtta gctaatctta ttgtaatgcc gacttcaatg
     8281 ttggctggct gtttatggcc attgtctatt acgccttctt atatgcaagc aattggtaag
     8341 ttattaccac aaaattgggt tttatcagcc atagctattt ttcaaagtgg agggacctta
     8401 tctcaggctt ggccatactt gttagctcta atgggaacag cactagcttt gattattttt
     8461 tcaagtttat tattaaaacc taccagacta taattagtct tttgttaaaa aatactttcc
     8521 taattagcta actaccaggt agccctttta ttggcttata tgcaataaaa gggttgcttt
     8581 ttgcttatat tttctctagt gcacttatct tttgttaaaa gcgattgcga tgttactgtt
     8641 gttactgtgt tttttagaga gcatattatc aaaagcgacc cctctataaa gttcgttttt
     8701 gttgataaat gggttgtcaa agtattttaa aaaacgtttt caataaacat aaaaactaat
     8761 gttattaaaa aaagttttga aaacgtattt attttatgaa atgtttttgt tacaataagc
     8821 atgtatcgaa tgctataaag ctgtcttgtt cgctatcagg ggtgcttgtg atgttatgtc
     8881 agatcaaaca agtctttaat tgggtgactt aacagattaa aagaaaagat ctaatcgtgt
     8941 tacttgatag tataattaat gcaaacagaa agtgtatccc aattcatagt ctcaggtgga
     9001 ggttaatatt caaaaataaa atcttgttgt tgtcttaaac taatcacatt aaaaggagat
     9061 atcatgatta acaagaaatg tataatatct gtttcattgt tgacactagc tattacgctt
     9121 actagtgttg aagaagttac ttcacgtcaa aatttgactt atgccaatga aatcgtaaca
     9181 caaaggccaa agagagaatc tgttattagt gataaatcga attttcccgt catatcacct
     9241 tacctagcaa gtgtggattt tggtgagaga aaaacacctt tgccaacacc tgataaagga
     9301 gtaaaagtaa ctactgaaca gtctattgct caagtaagaa aggggcctga agaaagaacc
     9361 tatactgtta ctggcaagat tacgagtgtg atcaatggct ggggaggcta tggcttttat
     9421 attcaagata gtgaaggtat tggactttat gtttatcctc aaaaagattt aggatacagt
     9481 aagggagata ttgttcaatt aacaggtaca cttactcgct ttaaaggtga tttacaactc
     9541 caacaggtga ctgcacacaa aaagttagag ttatcttttc cgacttctgt taaagaagca
     9601 gtaatatcag aattagaaac accaacaccc tcaacattag ttaagttatc tcacgtgaca
     9661 gttggagaat tatcaactga tcaatataac aacacatctt tccttgtaag ggatgatagt
     9721 ggtaaaagta tagttgttca tatagatcat cgtacagggg ttaaaggggc tgatgttgtt
     9781 actaaaataa gtcagggtga tttgattaac ctcacagcca tattgtctat tgttgatggt
     9841 cagttacaat taagaccgtt ttctcttgaa caattggaag tggttaaaaa ggtcacaagc
     9901 tcaaatagtg atgcttcatc tcgtaatatt gtgaaaatag gcgagattca aggagctagt
     9961 catacgtcgc cacttctcaa aaaagcggtc accgtagaac aggttgttgt cacttattta
    10021 gacgattcca ctcattttta tgttcaagat cttaatggtg atggtgattt ggcgacttca
    10081 gatggtattc gtgtttttgc taaaaacgct aaggttcaag tcggcgatgt tttgaccatt
    10141 tcaggtgaag tggaagaatt ctttggtcgt ggttatgagg aacgtaagca gactgacctt
    10201 accatcaccc aaattgtggc taaagcagtg accaaaacag ggacagctca agttccatca
    10261 ccgcttgttt tagggaaaga tcgtatcgcg ccagccaata ttattgataa tgatggcttg
    10321 cgtgtgtttg atccagaaga agacgctatt gattattggg aatcaatgga aggcatgtta
    10381 gtggcggttg atgatgctaa aatccttggt ccaatgaaaa ataaagaaat ttatgtctta
    10441 cctggctcta gtacaagacc gttaaataat tcaggtggag tattacttcc agctaattct
    10501 tataacacag atgtgattcc tgttcttttc aaaaaaggca aacaaattat taaagcagga
    10561 gactcttaca aaggaagatt agctgggcca gtatcttata gctatggtaa ttacaaggtc
    10621 tttgttgatg acagcaaaaa catgccaagt ttaatggatg gtcatctaaa acctgaaaaa
    10681 acaaacttgc aaaaagacct tagcaagtta agcattgctt cttacaatat tgaaaacttc
    10741 tcagccaatc cttcttcaac taaagatgag aaggtcaaac ggattgccga atcttttatt
    10801 catgatctga atgctccaga cattattgga ttaattgaag tccaagataa taatgggccg
    10861 actgatgatg ggacaacgga tgcgacacaa agcgcgcaac gcctcattga tgctattaaa
    10921 aaactaggtg gcccgactta tcgttatgtt gatattgctc cagaaaataa tgttgacgga
    10981 ggtcaaccag gtggtaatat tcgaacagga ttcctttatc aaccagagcg cgtcagcctt
    11041 tctgataagc caaaaggcgg tgctcgtgat gctctaactt gggttaatgg agaattaaac
    11101 cttagtgttg gtcgaattga tccaactaac gccgcttgga aagatgttcg taaatcacta
    11161 gcagcagaat ttatcttcca aggtcgtaaa gtcgttgttg ttgcaaatca tttgaactct
    11221 aagcgtgggg ataatgctct ttatggtcgt gtgcaaccag tcacttttaa atctgagcaa
    11281 agacgtcacg tcttggctaa tatgctagca caatttgcga aagaaggggc aaaacaccaa
    11341 gctaatattg tgatgctagg tgactttaat gattttgaat tcacaaagac gattcaatta
    11401 atcgaagaag gtgatatggt taacttggtg agccgacatg atatttcaga tcggtattct
    11461 tattttcacc aaggcaataa tcagaccctt gataatatat tagtttcacg ccatttactt
    11521 gatcactacg aatttgacat ggttcatgtg aattccccat ttatggaagc tcacggacgc
    11581 gcatcagatc atgatccatt gttacttcaa ttatcatttt ccaaagaaaa tgataaggca
    11641 gagtcttcta aacaaagtgt aaaagctaaa aaaacttcaa aaggaaaact gttgccaaaa
    11701 acaggagata gtcttgttta tgtgataacg ctactaggaa cggctagttt attagtgcct
    11761 attttattat tgactaaagg caaaaaggaa tcatagcgat ttgaagaatt ggagttcata
    11821 aagagtcgtt aaaggcttga tatacttacg ttagacctta agctaaaatg gatgactata
    11881 taaaaactaa tattgataac aaaagaagat aacaataaga cagctttact tgctaaagac
    11941 ttttgtcaag ctaattgttt tatggtacaa tgtaaccgtt gctttgcaac ccttggtgct
    12001 tagttccctt tcaccaagca tattagaaac gtagatagct tttgagagtt atccagacgt
    12061 taaaggagaa aaaatgacaa aattgactgt acacgactat gttcacattg ggctagtagc
    12121 tgccttgtat gttgtcttaa ctattacccc gcctttaaat gcgatttctt atgggatgta
    12181 tcaatttaga atatctgaaa tgatgaattt cttagctttt tatcatcgca agtatattat
    12241 tgcggtgact cttggatgta tgattgctaa cttttatagt ttcggactga ttgatgtctt
    12301 tgtaggcggc ggttcaactc ttatttttgt gaccttgggt gttattttgt ttagtaagta
    12361 tcaaaaagat tatcttttta atggcatttt taataaagct tttgtttact tttctttctt
    12421 ttttgcaact tccatgttta ctgtagcaat cgaactttac ttctttggag ctccattttt
    12481 attaacatgg tttacaactg cgttgggaga attagtatct ctgctcatag gatcacttat
    12541 tattgataag ttgtctcaaa gaatttcctt ttagtaatgc atcatactca aaagagttgg
    12601 gtcaataccc ttctcttttt tatgttgttt gtaatgttaa aatcgttcta gatagaaata
    12661 tttaacactt tagctaatag taccatatgg agtggccaac gattactttt gatgttgtta
    12721 tgatatagaa atagctcatt tgttatcttt tatgataaaa taaaagtatg aaaaaacgca
    12781 taaaagaatt aacagatctt cttaaccgtt accgttatga ctattatact aaagatgccc
    12841 catcagtttc tgacagtgac tatgataagc tttatcgtga actggtgact ttagagcagt
    12901 catatcccga gtatgtcttg caagatagcc caacgcagca ggttggaggg actattttaa
    12961 aggggtttga aaaatatcga catcagtatc cgctttttag tttgcaggat gctttttcac
    13021 gtgaggagct ggatgctttt gataagcgcg tcaaggccga atttccgaat gccacctatc
    13081 tagcagagtt aaaaattgat ggtttatcta tttccttgag ttatgagaat ggcttcttac
    13141 aggttggagc aacacggggt gatggcaata tcggtgaaaa tatcacagaa aatatcaaaa
    13201 aaataaagga tattcctcac caattgagtg agcctttaac catcaccgtt cgaggagagg
    13261 cttacatgtc tcgtcagtcc tttaaagcga tcaatgaagc acgccaagaa aatggggaga
    13321 ctgaatttgc taatcctaga aatgctgccg ctgggacact aaggcagcta gatacggcag
    13381 tggttgctaa gcgtgaacta gccacttttt tgtatcaaga agctagtccg acagctataa
    13441 atcaacaaaa tgaggtctta gcagaattag cagatctagg tttttcagta aatccgtatt
    13501 atcaactcac atcgtctatg gatgagattt gggattttat caaaactatt gaggcaaaaa
    13561 gagatcaatt agcttatgac atagatggcg ttgttattaa agttaatagc ctagccatgc
    13621 aagaagagct aggggttacg gttaaagctc cacgctgggc cattgcttac aaatttccag
    13681 cagaagaaaa agaggcagaa atcctttcgg ttgactggac agtgggacga acaggcgtgg
    13741 tcacacctac agcgaatcta actcctgtgc aactagcggg gacaaccgtg agtcgtgcaa
    13801 ccctacataa tgtggattat attgccgaaa aagatatccg tattggcgat acagtgattg
    13861 tatataaggc aggggacatt attcctgctg tcttaaatgt cgttatgagt aagcggaacc
    13921 agcaagaagt catgcttatt cctaaactat gcccatcttg tggtagtgaa ttagttcatt
    13981 ttgaagatga ggttgctttg cgttgtatta atccgttgtg tcctagtttg attcagcgaa
    14041 gtttggagca ttttgcaagt cgtgatgcca tgaacattac tgggctggga ccagctattg
    14101 tggaaaaact atttttagcg gggtttgttc atgatgttgc tgatatttac cagttgacca
    14161 aagaggattt catgcaatta gatggcatca aagaaaagtc agctgataaa ttgctcgctg
    14221 cgattgaggc ttctaaatca aattcagctg aaaaactgtt atttggtcta ggaattcgtc
    14281 atattggctc taaagttagt cgcttaattt tagaggtata cggagatatt tctgctcttt
    14341 taaccgctaa agaagaggaa atcgcaagga tagatggtct tggctcaacg attgctcaat
    14401 cacttactca atactttgaa caaaaaacgg ctgcgatttt agtagacgag ttaaagacag
    14461 caggtgtcaa catgcattac tcaggtcaaa aagttaatag tgacgcagcg ctttttggtc
    14521 taactgttgt tttaactggc aaattaaatc agctgaaccg aaatgaggcc aaagataaat
    14581 tagaggcatt aggtgccaaa gttactggaa gtgtatctaa gaaaacagat ttagttattg
    14641 caggtagtga cgctggttct aagctagaaa aagcaaagag cttaggaatt cggattgaag
    14701 atgaagattg gctacgccag ctttaagtga ggtaatgtta tgaaaaaaca attgagagca
    14761 cgtctcattt ataatccaac gtcaggacaa gaacttatga gaaaaagtgt tcctgaagtt
    14821 ttagacatat tagaagggtt cgggtatgaa acatctgcct ttcaaacaac agcccaaaag
    14881 aactctgctc taaatgaagc aagaagagcg gcaaaggcag gttttgactt attgattgct
    14941 gctggaggtg atggcactat taacgaagtg gtcaatggaa ttgctccctt gaaaaagcgc
    15001 cctaaaatgg ccattattcc aacaggtacc actaatgatt ttgctagagc gttaaaagta
    15061 ccaagaggaa atccgagcca agcagcaaaa cttatcggaa aaaatcagac tatccagatg
    15121 gatattggta gagctaagaa agatacttat ttcatcaata ttgctgcagc aggaagtttg
    15181 acggaattaa cttacagtgt accaagtcag ttaaaaacga tgtttggata cttggcttat
    15241 cttgctaaag gagtagaact gctcccaaga gttagcaatg tgcctgttaa aattacgcat
    15301 gacaaaggcg tctttgaagg tcaagtttct atgatttttg cagctattac caattctgtt
    15361 gggggatttg aaatgattgc tcctgatgca aaactagatg acggtatgtt tacgctcatt
    15421 ttaataaaga cagcaaatct ttttgaaatt gtacatcttt tgcgtttgat tttggatggt
    15481 ggtaagcata ttacagatcg ccgtgtcgaa tacattaaga ccagtaaaat agtcattgaa
    15541 ccccaatgtg gtaagcgaat gatgattaat ttagatggcg agtacggagg agatgctcca
    15601 attacattag agaacctaaa aaatcatatc actttttttg cagatactga tttgatttct
    15661 gatgacgctt tagtcttaga tcaggacgaa ttggaaattg aggaaatcgc aaagaaattt
    15721 gctcatgaag tagaagactt agaacaagaa ttagaagaat aatacaatag ttattagcta
    15781 ctgacagttt agtcaaatgc actactatta gaatctaaga tttttaaatc aattgaggta
    15841 gtgttttttg atgcgctcaa agagtcaatt tattcatatg aggggcccat ttgaggtctc
    15901 tcttttttga tcatatgcaa gaaaatgcca tgttttaggg gtgttattat accctttttg
    15961 gaatcttgtt gcctttttgt tataataaga gtgtaattct atttttaaaa agatcttaac
    16021 aaagacagac tcgtttatca aaaaggttag tattagtcta agaaagcgta ctcagtctaa
    16081 agaaatctgt tgacattctt aattttaagg aatagaatag caaagtaaaa aaaaattaaa
    16141 ggagtattct actatgaatc ctattttcgc attggctttg gcctgttttg gtgtttctct
    16201 tgccgaaggt ttcttgatgg caaatctttt taaagcagca tctcgccaac cagaaatcat
    16261 tggtcaatta cgttcattaa tgatcttggg tgttgccttt atcgaaggta ctttctttgt
    16321 tacccttgtt atggccttca ttcttaaata acagcctatt tgataataga aaaggagggt
    16381 gttagatgga agaagctaaa atacccatgc taaagcttgg tccaataacc tttaatttga
    16441 ccctacttgc tgtttgtatt gtcacaattg ctgttatctt tgcctttgtt ttttgggcaa
    16501 gtcgccaaat gaaattgaaa ccagaaggga agcaaactgc tttagaatat ttaatcagtt
    16561 ttgtggatgg tattggagaa gagcacttag atcataatct acaaaaatct tattcgctgt
    16621 tactctttac catttttctc tttgtggccg tcgctaataa tttagggtta tttactaagt
    16681 tagagacagt taatggctat aacctatgga cctcgccaac agccaacctg gcttttgacc
    16741 ttgctctatc tctttttatt accttaatgg tacacattga aggggttaga cgtcgtggct
    16801 tggttgccca tttgaaacgt ttggctacac cgtggccaat gactccgatg aatttattag
    16861 aagagttcac aaatttctta tcacttgcca ttaggttatt cggtaatatc tttgccgggg
    16921 aagttgttac aggtttgatt gttcaactgg ccaattatcg agtttattgg tggccgatcg
    16981 ctttcctagt caatatggcg tggacagcct tttcagtctt tatttcctgc atacaggctt
    17041 ttgttttcac aaaactaaca gcgacctatc taggaaagaa agttaatgaa tcagaagaat
    17101 aaggaaggag aacaaacgaa tgtcaatcac atttggtgaa ctcgttggga attttattct
    17161 agtaacaggt tctgtaatcg tcttgttact cttgatcaaa aaattcgctt ggggtgcaat
    17221 tgaatcgatt ttacagacac gctcacaaca aatctctcga gatattgatc aggctgagca
    17281 atcacgtcta agtgctcaac agttagaggc aaaaagtcaa gctaacctag atgctagtcg
    17341 tttacaagca agtaaaatca ttagtgatgc caaagaaatt ggtcaattac aaggtgataa
    17401 attggtggca gaagctactg atgaagcaaa acgcttgaaa gaaaaagcgt tgacagatat
    17461 tgaacaaagc aaatcagacg ctatttcagc agtcaaaaca gaaatgtctg atttaacggt
    17521 tcttttagcg gaaaaaatta tgggagccaa tcttgataag acggcgcaaa gccagcttat
    17581 tgacagttat cttgatgact taggagaagc ttaatgacca aaaaagaaca ggctcttatc
    17641 gagcaatatg caaaaagcct tgttgaggta gcaagtgaac atcattctct tgatacctta
    17701 caagctgatg tgcttgcgat tttagagacg tttgtaacaa ctaatcttga tcaaagtcta
    17761 tcaagtctag ctgttccgca tgctgaaaaa ataaaattgc taaccttatt aaagggaaat
    17821 aattctgttt atatgaataa tttcttgaat ctcattttac aaaacgaacg tgaagcttat
    17881 ttgtatcaaa tgcttcaggc tgttttaaat gaaattgcaa tagtttcaaa tcagtatgat
    17941 gtgactgtta cctcatcact acctttgact gaggagcaaa aaagccgtgt tcgagcagtt
    18001 gttgcaaaga aatttgctgt aacagcgggt cgtttaattg aaaaagtaga tccttcgctt
    18061 attggaggat ttattatcag cgtcaataat aaagtaattg ataccagtat tcgtcgtcaa
    18121 ttgcaagcat ttaaaatgaa tttaaaatag aaagtggtgt gacttttggc aattaatgca
    18181 caagaaatta gcactttaat taaaaagcaa attgagaact tccagccaaa tttcgatgtc
    18241 acagaaactg ggatcgttac ctatattggt gacggtattg cacgtgcccg tggattagat
    18301 aatgccatga gtggtgaact tcttgaattt gaaaatggtg cctacgggat ggctcaaaac
    18361 cttgagtcaa atgatgtggg tattattatt cttggtgatt tttcagcaat ccgtgaagga
    18421 gatgtggtta agcgcaccgg taaaatcatg gaagtaccag ttggtgaagc tctcattgga
    18481 cgtgtggtaa acccacttgg acaaccagtt gatggcttgg gagatattga aacaactggc
    18541 tttagaccag tagaaacgcc agctcctggt gttatgcagc gtaaatccgt ttctgaaccc
    18601 ttacaaactg gattaaaagc aattgatgct ttggttccaa ttggtcgtgg gcaacgtgag
    18661 ttgattatcg gagaccgtca aacaggaaaa acatccgtag ctattgatgc gattttgaac
    18721 caaaaaggtc aagacatgat ttgtatctat gtggctattg gtcaaaaaga atcaaccgtt
    18781 cgtacacaag ttgaaaccct tcgccgttac ggtgccttgg attatactat tgttgtgaca
    18841 gcgtcagcct cacaaccatc accattgctc ttcatcgctc cttatgcggg tgttgccatg
    18901 gctgaagaat ttatgtacca aggcaagcat gtcttgattg tctatgatga tttatcaaaa
    18961 caagcggtgg cttatcgtga attgtctctc ttgcttcgtc gtccaccagg tcgtgaagct
    19021 tacccagggg atgttttcta cttgcatagc cgtcttttgg aacgctctgc aaaagtttct
    19081 gatgacttag gtggaggttc tatcacagct ctaccattta tcgaaacaca ggccggagat
    19141 atctctgcat atattgcgac taacgttatt tcgattacag acggacaaat cttcttgcaa
    19201 gagaacctct ttaattcagg aattcgtcca gcgattgatg caggatcatc tgtctcacgt
    19261 gtaggtggtt cagctcaaat taaagcgatg aaaaaggttg ctggtactct tcgtttggat
    19321 ttggcttcct atcgtgaatt agaagccttt acccaatttg gttcggacct tgatgctgca
    19381 acacaagcaa aacttaatcg tggtcgccgt acggttgaaa tcttgaagca accattgcat
    19441 aaaccgttac ctgttgaaaa gcaagtcgtt attctttatg cccttactca tggtttctta
    19501 gatgatgttc ctgtagatga tattttggct tttgaagaag ctctttacga ctactttgac
    19561 gttcattaca atgatttatt tgaaactatc cgtaccacaa aagaccttcc tgaagaagct
    19621 gcccttgatg cggctattaa agcgtttaaa gaacactcaa actttaagtc atagagggag
    19681 gatactagta tggcaggctc tctaagtgaa attaaagcta aaattatttc aactgagaaa
    19741 acaagtaaaa tcactagtgc catgcgtatg gtttcttctg caaaacttgt tagatctgag
    19801 caagcagctc gtgattttca aatttatgcc tcaaaaattc gccagattac cacagattta
    19861 ttgaaatcag aattaaccat aggatctgat aatccgatgt tggtgtctcg tcctgtcaaa
    19921 aaaacaggct atattgtcat cacgtctgat aaaggacttg ttggaggtta caattcaaaa
    19981 atcttgaaat ctgttatgga tatgattaca gagtaccatg ctgatggtga ctatgaaatc
    20041 atttctattg gtagtgttgg ttcagacttc ttcaaagcaa gagggatgaa tgtggctttt
    20101 gaacttcgtg gacttgcgga tcaaccaagt tttgaacaag tgagacaaat catttcacaa
    20161 tccgttgaca tgtttgtcaa tgagattttt gatgagttat atgtctgtta caatcaccat
    20221 gtgaatagct taaccagcca agtccgtgtt caacagatgt tgccaatttc tgacttggtt
    20281 gctgatgaag cagcagaaga aggtgttact gggtttgaat tggaacctaa tcgtcatgat
    20341 attttagatc aattgttacc tcaattcaca gaaagtttaa tttatggggc tatcattgat
    20401 gctaaaacgg ctgaacatgc agcaggtatg actgctatgc agacagcgac agataacgct
    20461 aagaatgtca ttaacgattt gaccatccaa tataaccgag ctcgtcaagc agcaattaca
    20521 caagaaatta ctgaaattgt tgcaggagca aatgcactag aataaaaaat aacgctgact
    20581 agcgattagg ttattgtcag cattcaattt tatcaatcga gataaaatga cttatgggac
    20641 ttttctattg aaagactgct cttttcagta taaaagaagt tagcaagact aactaagccc
    20701 tgactatcga atataaggag aaatgaatga gctcaggcaa aattgctcag gttgttggtc
    20761 cagtagtaga cgtcatgttt gctagtgggg acaaacttcc agagattaat aatgcattga
    20821 ttgtttataa agatagtgat aaaaagcaaa aaatcgtcct tgaagttgct ctggaacttg
    20881 gtgacggtat ggtgcgaaca atcgctatgg aatcaactga tgggcttaca cgtgggttag
    20941 aagttcttga cactggtcgt gcgattagcg taccagtagg taaagaaact ttgggacgcg
    21001 tctttaatgt acttggagaa accattgatt tggaagaacc atttgcagaa gatgttgacc
    21061 gtcagccgat ccataaaaaa gcaccatcgt ttgatgaatt atcaacatca tcagaaattc
    21121 ttgaaactgg tatcaaggta attgaccttc ttgcccctta ccttaaaggt ggtaaagttg
    21181 gacttttcgg tggtgccgga gttggtaaga ctgtccttat ccaagaatta atccacaata
    21241 tcgcccaaga acacggaggt atttcagtat ttaccggtgt tggtgagcga acacgtgaag
    21301 gaaatgacct ttactgggaa atgaaagaat caggcgttat tgaaaaaacc gccatggttt
    21361 ttggtcagat gaatgagccg cctggggcac gtatgcgtgt agcccttact ggtttaacca
    21421 ttgctgagta tttccgtgat gtagaaggcc aagatgtttt gctctttatt gataatatct
    21481 tccgtttcac tcaggcaggt tcagaagtat cagccctctt aggccgtatg ccttctgctg
    21541 ttggttacca accaacactt gctactgaaa tggggcaatt gcaagaacgg attacatcaa
    21601 ctcaaaaagg ttctgttaca tctatccaag cgatttatgt accagcagat gattatactg
    21661 accctgcgcc agcaacagca tttgctcacc tggattcaac aactaacctt gaacgtaaat
    21721 tgactcaaat gggtatttac cctgcggttg atccattggc ttcaagttca cgggctttat
    21781 cacctgagat tgttggtgaa gagcactatg ctgtggcaac agaagttcaa cgtgtgcttc
    21841 aacgctaccg tgaattacaa gacatcatcg ctattttggg gatggatgaa ttatcagatg
    21901 aagaaaaaac attggttgga cgtgcgcgtc gtatccagtt cttcctctca caaaatttta
    21961 acgttgctga acaatttacc ggtcttcctg gttcttacgt gccagttgct gagacagttc
    22021 gcggatttaa agaaattctt gaaggaaaat acgatcacct tccagaagac gcctttcgtt
    22081 cagttggtcc aattgaggat gtgattaaaa aagccgaaaa aatgggcttt tagtgaggtg
    22141 atgccatgac acaaatgact gttcaagtgg taacgccaga tggaatcaaa tatgatcacc
    22201 atgctaaatg tatttctgta acaacaccag atggggaaat ggggatttta cctaatcaca
    22261 tcaatttaat tgcacctttg caagtccatg aaatgaaaat tcgccgaggt ggtgaagatg
    22321 aaaaagtgga ctggattgca atcaatggtg gtattattga aatcaaagat aatgtggtta
    22381 ccattgtcgc tgattctgca gaacgtgacc gtgatatcga tgtcagccga gcagagcgag
    22441 caaaactaag agcagaacgt gaaattgcac aggctgaaac gacccacaac attgatgaag
    22501 ttcgtcgtgc caaggttgcc ttgcgccgcg ctttgaatcg tatcaacgtt agtaaaaaat
    22561 aagtggtgtt gataaaagac aaggataagt aagaaaggtt tttaacctat tattttgttt
    22621 gctgattctt tttaacatca gtttctgaga gtttgaccat actaccttct ctaaacacgt
    22681 tattattgtt gagaggagtt atatggggga actctttttt gtgtccacgt tgttagtaga
    22741 aactcagtaa tgacgcttaa tgtattttta ggctatcaac ttagtcagag aagatgtcaa
    22801 cttaattgat aagttggacg gatcaagatg gtatgttata ataatcctat ggaattatta
    22861 atgaagatca ttgccttttc gtgtcattta ttttttattg gccttagtta ccaattattg
    22921 attagtgtga ttgactggac aaaatttagt cattatcatc cagaaaatct tggccggcta
    22981 cgactttttg tctttttatt agctactgcc ctagggtatt tggtgagcca ttgtatgctg
    23041 gaattgcttc aaattagcca gacgctcttt tttgagttcc gctaatactg gaataaaaga
    23101 agtatggtat aattttacta cgactaagag atagataagg gagaaaattg tggataaaat
    23161 aatcattgaa ggtggtcaaa cacgcttaga aggagaagtt gttattgagg gtgctaaaaa
    23221 cgcagttctt cctttactgg cagcatctat tttaccttca aaaggaaaaa caattcttag
    23281 aaacgttcct attctatctg atgtttttac catgaataac gtggtacgtg gtttagatat
    23341 tcgtgttgat tttaatgaag cagctaacga aatcacagtt gatgcctcag gacacatttt
    23401 agatgaagcc ccttacgagt acgtgagcca aatgcgtgcc tctattgttg ttttaggacc
    23461 aattttggca cgtaatggcc acgcaaaagt atcaatgcct ggaggttgta cgattggcag
    23521 taggcctatt aatttgcact taaaaggatt agaggctatg ggggcaacga ttactcaaaa
    23581 aggtggagat attaccgctc aagcagatcg actgcaaggt gccatgattt atatggactt
    23641 cccatctgta ggagctaccc aaaacttgat gatggctgcc actttagctg atggtgtgac
    23701 cactattgaa aatgctgctc gtgagcctga aattgttgat ttagctcaat ttttgaataa
    23761 aatgggagct agaattcgtg gtgctggaac agagacgtta acgataacag gcgtcacgca
    23821 tttacgaggc gtagaacatg atgttgttca agatcgtata gaagccggta catttatggt
    23881 tgcagcggcg atgacttcag gcaatgtttt gattagagat gctgtttggg aacataatcg
    23941 tccattgatt tcaaaattaa tggaaatggg tgtttctgta acagaagaag aatacggtat
    24001 tcgcgttcaa gcaaacacgc caaagctcaa acctgtaacg gttaaaacct tgcctcatcc
    24061 aggttttcca acagacatgc aagctcaatt tacagcttta atggcagtgg tcaatggaga
    24121 gtctactatg gttgaaactg tctttgaaaa tcgatttcaa catctggaag aaatgcgacg
    24181 catgggctta caatctgaaa tccttaggga aactgccatg attcatggtg gaagacaact
    24241 gcaaggtgct cctgtgatgt caacagattt acgtgccagt gctgccctta tcttgacagg
    24301 gattgttgct caaggagtta caatagttaa taatttggtt catttagatc gtggctacta
    24361 tcaatttcat gaaaaattag caaagcttgg agctactatt agtcgtagca gtgaggtcta
    24421 gcttatgaca aatggtttaa aatatgtctt agaacaaatg ttattacttt tagtaattgc
    24481 tgccttggcg tgtctttttt tagccattgg acttatgatt ggttatagtt ttatgggaga
    24541 tggccatagt ccatggcata ttttatctat ggataagtgg gcagagttag tgaataaatt
    24601 tactggaaag taggccttgc ctacttttta tagcatctga gaggaagtat gttaacaagg
    24661 aaaaaacgaa aaagggtgca agagcaaaag gttcctaaaa gagctaatgc cttacttact
    24721 aagtcgacac gacagtatcg aaatcgctat caaacggaca atgcttatcg taactttaag
    24781 ccagtaggtt ggcaccgatt gcaccactta aaaggaagtt atgatcacgc ggttgataga
    24841 gggcatttgc taggttatgc tttagttggt ggactgaaag gttttgatgc ttaccagtaa
    24901 tcctgataat attgccactc aactaagttg ggctaatcaa gcaaataaac cctactcgac
    24961 aggtcagaat tactatgaag gtttagtacg tcgtgctttg gataaggggc atcgcgtccg
    25021 ctaccgtgtc accctacttt atgatggtga taatctacta gccagcggta gccatttgga
    25081 ggctaaattc tctgatgaca gcttgacttt taacgtgttt gttccaaatg tccaaccagg
    25141 attgaccgtt gactatcgga cgggacaaat agctatcaat ctctaagcga aaagtcactc
    25201 acgccaaacg catgaagaaa
//
LOCUS       DATTYN010000029        24755 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.29, whole genome shotgun sequence.
ACCESSION   DATTYN010000029 DATTYN010000000
VERSION     DATTYN010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24755
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.29"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..268
                     /locus_tag="VB649_001432"
     CDS             <1..268
                     /locus_tag="VB649_001432"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670379.1"
                     /translation="LFAIALASGLIFSSSQAYAAEIQQETFKTKIEAIYQALLTIENA
                     PFNQYYTIKEIPGSDGQPSKFVYEVSIVEKVGSIGPKDSSEINE"
     gene            917..2266
                     /locus_tag="VB649_001433"
     CDS             917..2266
                     /locus_tag="VB649_001433"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEP1670380.1"
                     /translation="MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSD
                     FLGWLDLPENYDKDEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEP
                     SLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDN
                     PRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEF
                     TLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL"
     gene            complement(2615..4123)
                     /locus_tag="VB649_001434"
     CDS             complement(2615..4123)
                     /locus_tag="VB649_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP1670381.1"
                     /translation="MLDYYLESDIIDQKILLAILLTEKELTMAAACSQTTLTALKIKQ
                     YLRQFNALFKGYLRIELIKSRIYCEVLNDKREAFFYDIFALSDTLKMLTFLLLDNPKH
                     KSIAVYTRKQGISQSKAYRLIHKLKHYLQDIGLNIVDNTVIGDELKIRYLIALLHKEY
                     GIILYDIQPADIETIHAFIFAAQKNLQPSAFLDRRFLFFDVLLMLTWKRHRYPVHLPH
                     LALFEHLKSLPIFDNIKTIAVDELAPRTRVTFSSDDFDYLFLIYLTTDNSFLSGYWTS
                     HQRQQLYHLITKDPDYHLLIHRLQALVGKYSDIHEHIPNLIPFFKRTLYNLQTLITFD
                     GYYFDQYQGNMLLLDKLETVIKDWLYDTGRQGSISSGHLHLMCLYLEQILESSIAPIN
                     ITVIESQETVGNVIANFITSTIPSYKVELSRVNILSDNIYPYDKPVDLVVTSQKLLPF
                     LKELGVFPKETRLVGLSLDCIQQQREDLIKTILALHQNHYQKRLEELWRVPS"
     gene            4628..4783
                     /locus_tag="VB649_001435"
     CDS             4628..4783
                     /locus_tag="VB649_001435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670382.1"
                     /translation="MMKKEILKELFQSLRTMDVDLKRQNDQALLVDVVSNQAYQRANT
                     IAKSNDL"
     gene            4811..5482
                     /locus_tag="VB649_001436"
     CDS             4811..5482
                     /locus_tag="VB649_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEP1670383.1"
                     /translation="MTRLLKRYPITIFLLGLTGLIFIAMQVVYGHLATGAQAIYQVGG
                     MFGLLVKAMPDQLWRLVTPIFIHIGFGHFFVNGLTLYFVGQIVEDLWGSSRFLLLYVL
                     SGVMGNAFTFWLTPETVAAGASTSLFGLFAAIVVLSFLGKNQALKDLGKSYQTLIVVN
                     LLMNLFMPNVSMAGHIGGVVGGALLSIVFPTKMRVITVKKTKRMLALVSYGIILVGVL
                     VLGFL"
     gene            complement(5582..6481)
                     /gene="galU"
                     /locus_tag="VB649_001437"
     CDS             complement(5582..6481)
                     /gene="galU"
                     /locus_tag="VB649_001437"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEP1670384.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQAKGKIELLKLVDETTSINLHFIR
                     QSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
                     AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIF
                     SILEKQEPGAGNEVQLTDAIDTLNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKH
                     PQVKDDLKAYIIQLGKALEKTKP"
     gene            complement(6514..7530)
                     /locus_tag="VB649_001438"
     CDS             complement(6514..7530)
                     /locus_tag="VB649_001438"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEP1670385.1"
                     /translation="MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINT
                     KHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVV
                     VMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKD
                     IEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIE
                     RNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWH"
     gene            7826..8275
                     /locus_tag="VB649_001439"
     CDS             7826..8275
                     /locus_tag="VB649_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEP1670386.1"
                     /translation="MSQVIGDLRELIHQIEQISDEIAKKYDVEHLAGPQGYVLVFLAK
                     HQNQEIFVKDIEKQLRISKSVASHLVKRMVKNGFINVMPSQVDKRYKQVVLAQVGRDK
                     LPLLRECRKDIEHYFLKEITKEELLTAKKVIEQLKQNMLTYKGDNDA"
     gene            8268..9974
                     /locus_tag="VB649_001440"
     CDS             8268..9974
                     /locus_tag="VB649_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670387.1"
                     /translation="MLKDAILRYKWYALGSFFMVIGVVASSLLQPHYLKSVLSAVIQN
                     NQEKIYEVGKPLLIIALLGLMSGAINTVLAAKIAQGVSADMREKTFRKIQDFSYANIE
                     AFNAGNLVVRLTNDINQIQSLVMMMFQILFRLPFLFIGAFIMAVQTFPQLWWVIVVMV
                     ILIALIMGLVMRQMGPRFGKFQRLMDKINRIAKENLRGVRVVKSFVQEQQQYTKFKET
                     SNDLLALNLSIGYGFSLMQPALMLVSYLAVYVSINVVSTMVETDPTVIGNIASFMTYM
                     MQIMFSIIVVGSMGMQVSRAFVSMARIRQILSTEPAMTFENEKEETISGSIVFDDVSF
                     TYPNDDEPTLKHISFAIEPGQMVGIVGATGSGKSTLVQLIPRLFDPQDGQILLGGKPI
                     KTLSQTTLRQSVSIVLQKAILFSGTIADNLRQGSAKADIDAMQKAAQIAQAKEFIDRM
                     NSRYESQVEERGSNLSGGQKQRLSIARGVINHPKILILDDSTSALDAKSEKRVQEALS
                     HKLEGTTTVIVAQKISSVVKADKILVLDQGQLIGEGTHAELVANNAIYREIYETQKGR
                     EE"
     gene            9977..11761
                     /locus_tag="VB649_001441"
     CDS             9977..11761
                     /locus_tag="VB649_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670388.1"
                     /translation="MKTGRFFWFYFKRYRFSFTVIAVAVILATYLQVKAPVFLGESLT
                     ELGKIGQAYYVAKMSGQTHFSPDLSAFNAVMFKLLMTYFFTVLANLIYSFLLTRVVSH
                     STNRMRKGLFGKLERLTVAFFDRHKDGEILSRFTSDLDNIQNSLNQSLVQVVTNIALY
                     IGLVWMMFRQDSRLALLTIASTPVALIFLVINIRLARKYTNIQQQEVSALNAFMDETI
                     SGQKAIIVQGVQEDTVTAFLKHNERVRQATFKRRLFSGQLFPVMNGMSLINTAIVIFV
                     GSTIVLSDKSMPAAAALGLVVTFVQYSQQYYQPMMQIASSWGELQLAFTGAHRIQEMF
                     DETEEVRPQNAPAFTSLKEAVAINHVDFGYLPGQKVLSDVSIVAPKGKMIAVVGPTGS
                     GKTTIMNLINRFYDVDAGSITFDGRDIRDYDLDSLRQKVGIVLQESVLFSGTITDNIR
                     FGDQTISQDMVETAARATHIHDFIMSLPKGYNTYVSDDDNAFSTGQKQLISIARTLLT
                     DPEVLILDEATSNVDTVTESKIQRAMEAIVAGRTSFVIAHRLKTILNADHIIVLKDGK
                     VIEQGNHHELLHQKGFYAELYHNQFVFE"
     gene            11879..12646
                     /locus_tag="VB649_001442"
     CDS             11879..12646
                     /locus_tag="VB649_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEP1670389.1"
                     /translation="MIDLQEILANMNPNQKINYDRVMQQMAKVWEKESVRPSILMHVC
                     CAPCSTYTLEYLTQFADITVYFANSNIHPKDEYHRRAYVTQQFVSEFNAKTGNTVQFL
                     EADYVPNEYVRQVRGLEEEPEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAAKM
                     QGIDLVQVKKDAKAFMADKDLDNDFTHIRFSYRGDEM"
     gene            12756..13202
                     /locus_tag="VB649_001443"
     CDS             12756..13202
                     /locus_tag="VB649_001443"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEP1670390.1"
                     /translation="MTKIRGFELVSSFTNPDLLPKRETTHAAGYDLSVAEAVTIAPGE
                     IKLVPTGVKAYMQDGEVLYLYDRSSNPRKKGIILINSVGVIDADYYGNEANEGHIFAQ
                     MQNITDHPVTLAVGERIVQGVFMPFLIADGDQARGERTGGFGSTGQ"
     gene            13283..14644
                     /gene="radA"
                     /locus_tag="VB649_001444"
     CDS             13283..14644
                     /gene="radA"
                     /locus_tag="VB649_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEP1670391.1"
                     /translation="MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKN
                     ARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKS
                     TLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
                     NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGE
                     IGLTGEIRRVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLNA
                     VFS"
     gene            14833..15330
                     /locus_tag="VB649_001445"
     CDS             14833..15330
                     /locus_tag="VB649_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEP1670392.1"
                     /translation="MSYFEHFMAANQAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFTNEGF
                     AKHIHEHLGVDVSGQDFLPFQDVEDSVREDMAKLRASSLIPDDVVINGAVYDVDTGKM
                     TQVME"
     gene            15461..16171
                     /locus_tag="VB649_001446"
     CDS             15461..16171
                     /locus_tag="VB649_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEP1670393.1"
                     /translation="MVDNRMRFTIDQNMQFPLVEIDLEHGGSVYLQQGSMVYHTENVT
                     LNTKLNGKGSGLGKLVGAIGRSMVSGESMFITQAMSNGDGKLALAPNTPGQIVALELG
                     EKQYRLNDGAFLALDGSAQYKMERQNIGKALFGGQGGLFVMTTEGLGTLLANSFGSIK
                     KITLDGGTMTIDNAHVVAWSRELDYDIHLENGFMQSIGTGEGVVNTFRGHGEIYIQSL
                     NLEQFAGTLKRYLPTSSN"
     gene            16353..17798
                     /locus_tag="VB649_001447"
     CDS             16353..17798
                     /locus_tag="VB649_001447"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEP1670394.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARRHGGTFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGMDWDESPETHENYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEFIGMSADEKAKYIAEREAAGIVPTVRLAV
                     NESGIYKWTDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVVDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEEEIFSREQLIALFDENRLSKSPAAFDQKKMDWMSNEYLKH
                     ADFETVYALCKPFLEEAGRLTEKAEKLVELYKPQLKSADEIIPLTDLFFSDFPELTEA
                     EKEVMAGETVSTVLQAFKAKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGRDKSIEHIKNML"
     gene            18193..19539
                     /locus_tag="VB649_001448"
     CDS             18193..19539
                     /locus_tag="VB649_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1670395.1"
                     /translation="MANSEYMFLLLSIIVYYMTKIYIFSFLSDITLPVWKQLTILALA
                     LFFNQFPYLSPLLIDPLLFLVVLRQETKQLFSLKALFLAVAPSVLVDLLSRFMGTIVI
                     PYLFLSSGIYLGHIIFDLLAYLLIFPSFAIINYMIGKDYKMICQSGYSKRSHNFYQTL
                     LIFVLVYYVDIFVILGFTDPFLHFHHSLFVPTPYKLLFLMFILLLVYLLSYFNHSSKE
                     YLKNELRREQQAYMTNLEIYGKHLEKLYRDVRAFQSDYLSRIERLGQAIKSESITQIQ
                     DIYAQTVHEANDYWDDKHYNISKLRKINISSIKSLLSAKIISAEKSGIDLNVEVPDNI
                     KETYIPELDLLLLMSIFCDNAIEAALEAQQPHMSIAYFLLDDYQMFVVTNTTKKKVDI
                     NKIFEEGYSSKGSERGIGLSNAQRILKKYPYLSLRTKSFDKEFSQTLTMPKEEVDR"
     gene            19536..20819
                     /locus_tag="VB649_001449"
     CDS             19536..20819
                     /locus_tag="VB649_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1670396.1"
                     /translation="MMVIYSMALFYATIFINSWVIFAKVSAIKLSWKRVSIIGISFVI
                     ANMIFDKVILIDQLFFIIVSLLSAPKKKLFEHMFNGFFTILIVELLFRVIGSFFLPAV
                     LGFSIGQINNNLKLLELCYLFVLPIFYLFSYIFSIDLSLIRFISEDKMKKWVFWMNTA
                     MFSYYFFAHFLVTVQSGFLALYFQYRSILVFIYLAIFIWVIVKLDRFAKDQLSQKLTQ
                     AQNERIAYLENYNQSIEQLYREIRTVKHDSENILISLKDSIDSGDIDLITRVYDTVIQ
                     QSATSMMRTNYEISSLDNIKEAVIRSIMNSKLLEAQYLGIELYIEIPDVIDHLPIKLI
                     DLIVLFTGLVDNAIETAKGSRRPFLSIAYFKQDNKQLFIIENSTKTNRVDIAKRFDAQ
                     QQNSAHFLTVLDSYPQITLSTKSDHYRLRQLLEMR"
     gene            20823..21563
                     /locus_tag="VB649_001450"
     CDS             20823..21563
                     /locus_tag="VB649_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1670397.1"
                     /translation="MMNIFILEDDFIQQTRIESIVVGILKETRIPCNQLEVFSTPQKL
                     FESIQERGDHQLYFLDIEIGEYTRCGLELAAAIRQKDPNAVIVFVTTHSEFAPISFKY
                     KVSALDFIDKAGGQKQFKEQIEECIRYTYDMMSSRESKDMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQ
                     LLYFENGDSCMVSRLKMKCLFERWEALR"
     gene            22103..22462
                     /gene="rnpA"
                     /locus_tag="VB649_001451"
     CDS             22103..22462
                     /gene="rnpA"
                     /locus_tag="VB649_001451"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEP1670398.1"
                     /translation="MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGI
                     SVGKKIGNAVTRNAVKRKIRHVIMALGYQLKSEDFVVIARKGVESLEYQELQQNLHHV
                     LKLAQLLEKGFESEEKH"
     gene            22428..23255
                     /locus_tag="VB649_001452"
     CDS             22428..23255
                     /locus_tag="VB649_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEP1670399.1"
                     /translation="MRKVLRVKKNIKIARIVPLVLLLVACGRGEVTAQSSSGWDQLVY
                     LFARAIQWLSFDGSIGVGIILFTLTIRLMLMPLFNMQIKSSQKMQDIQPELRELQKKY
                     AGKDTQTRMKLAEESQALYKKYGVNPYASLLPLLIQMPVMIALFQALTRVSFLKTGTF
                     LWVELAQHDHLYLLPVLAAVFTFLSTWLTNLAAKEKNVMMTVMIYVMPLMIFFMGFNL
                     ASGVVLYWTVSNAFQVVQLLLLNNPFKIIAERQRLANEEKERRLRERRARKKAMKRK"
     gene            23267..24181
                     /locus_tag="VB649_001453"
     CDS             23267..24181
                     /locus_tag="VB649_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEP1670400.1"
                     /translation="MVLFTGKTVEEAIETGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGISDKTVYKADKKATRGVPEDINQKNAPAVNSADVEPEEIKATQKLEAED
                     TKVVPLMSEDSPAQTPSNLAETVTETKAQQPSIPVEESEVPQDAGNDGFSKDIEKAAQ
                     EVSDYVTKIIYEMDIEATVETSNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNF
                     LHDRYSKNFSVSLNVHDYVEHRTETLIDFTQKVAKRVLESGQDYTMDPMSNSERKTVH
                     KTVSTIEGVESYSEGNDPNRYVVVSLQR"
     gene            24496..24630
                     /gene="rpmH"
                     /locus_tag="VB649_001454"
     CDS             24496..24630
                     /gene="rpmH"
                     /locus_tag="VB649_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEP1670401.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLAARRRKGRKVLSA
                     "
BASE COUNT         7626 a         4332 c         5117 g         7680 t
ORIGIN      
        1 attattcgca atagctttag cttcaggtct tatctttagc agttctcaag cttatgcagc
       61 tgaaatacaa caagaaactt tcaagacaaa aatagaagct atttatcaag ctttactaac
      121 tatagagaat gctcctttta accaatacta cacaataaag gaaattccag gatctgatgg
      181 ccagccttct aagtttgttt atgaagttag cattgtagag aaagttggaa gtatcggtcc
      241 aaaggatagt tctgaaatta atgaataaac ttttgaaatt tttaaaatca tgcaaatcta
      301 tattttgcat gattttttat agaaatgctt ctagcatttg caaaatctac tcctattttc
      361 tatataaaaa atttatatat tggaatgcgt atatcgctta aaataatagc tctgccgtat
      421 gtaaaataat gttcaataca tggcacaaag catcttttgg cgagttttta aaagggcttg
      481 ctttttaagt attcaaatga ttgccatttt tagataatga gaataagtaa tgttaagaag
      541 atagcatgag aaagtattta caggtgattg gggcttcaat tgcctttgtg ggtgtggctt
      601 tatgcattga tcatatgcat gatggggtta ttacccgtat tgaaatgata aaatccttaa
      661 aataagttat taaggtaaag cggcctcagg gccttttttc atgatatttt taggaaatat
      721 gaaatcctat tttctcttaa aaaaccacta tgatgagaat atgcttgcat tgacacatgt
      781 tttatgtctg aaaaaacgaa aaccttttca aaaaacctag ctttttcaca ggtgaaaacc
      841 actaaaaacc attgaaatat tagatagaaa aggttatcat actaatgaaa cttaaaattt
      901 taagggagcg aaactcatgt cacatattac atttgattat tcaaaagtcc tcgagtcatt
      961 tgcgggacaa catgaaattg atttcttaca aggccaagtc acagaagctg acaagttatt
     1021 gcgtgaagga actggaccag gttcagattt cttgggctgg cttgatcttc cagaaaacta
     1081 tgataaagat gaatttgcac gtatcttgac tgctgctgaa aaaattaagt cagacagcga
     1141 agttcttgtg gtgatcggta ttggtgggtc ataccttggt gccaaagctg ctatcgattt
     1201 cttaaaccat cactttgcta acttgcaaac tgccaaagag cgcaaagcgc cacaaattct
     1261 ttacgctgga aactctattt catcaactta cttagctgac cttgtagagt acgttcaaga
     1321 caaagagttc tcagtaaacg tgatttctaa atcaggaaca actactgagc cagctattgc
     1381 tttccgtgtc ttcaaagaac ttttggttaa aaaatatggc caagaagaag ctaacaaacg
     1441 tatctacgct accacagaca aagtgaaagg tgctgttaag gtagaagctg acgctaacaa
     1501 ctgggaaaca tttgtggtgc cagataatgt tggtggtcgt ttctcagtct tgactgctgt
     1561 tggtttgctt ccaattgctg catcaggtgc agatatcaca gctcttatgg aaggtgcaaa
     1621 tgcagcgcgt aaagaccttt cttcagacaa aatctctgaa aacattgctt accaatacgc
     1681 tgctgttcgt aatgtgcttt accgtaaagg ctacatcact gaaatcttgg ctaactacga
     1741 gccatctctt cagtactttg gcgaatggtg gaaacaatta gccggtgaat cagaaggaaa
     1801 agaccaaaaa gggatttacc caacttcagc taacttctca acagaccttc actcacttgg
     1861 tcaatttatc caagaaggtt accgtaacct ctttgaaaca gttattcgtg ttgataaccc
     1921 tcgtaaaaat gttatcattc ctgaattagc agaagaccta gatggtcttg gttaccttca
     1981 aggtaaagac gttgattttg ttaacaagaa agccacagat ggtgtgcttc ttgcccacac
     2041 agatggtggc gtgccaaaca tgtttgtcac tcttccagct caagacgaat ttacccttgg
     2101 ttacactatt tacttctttg agcttgccat cgctgtttca ggctacatga atgctgtcaa
     2161 cccatttgat caaccaggtg ttgaagctta caaacgtaac atgtttgcgc ttcttggaaa
     2221 accaggtttt gaagcattat cagcagagct taacgctcgc ctctaatcaa cagatagtca
     2281 aaaagacttc ttccttgtac aagagcttaa aagttagcca agcaatctaa gaattggggc
     2341 ggcacttcca tcatcaagtg gatacaaggt taagtaaaag cgataataaa gtgcgcttcc
     2401 agaacatggg agcgcacttt attatgccaa atttcagata agaccttcaa aaaagggaag
     2461 aagatcctac aagaggagtt gaaccgctaa aacagttcca gtgctgtttc taggcgaata
     2521 gcaatggtta aaaagagagc ttatcaaggt tgcaagtgac aaccttaaag acccccctag
     2581 actgtgaaag tatctaggag ggactgtcaa aaaattaaga aggaactctc caaagttctt
     2641 ctaaacgttt ttggtagtgg ttctggtgca aggctaagat ggttttgatt aaatcttcgc
     2701 gctgctgttg gatacagtcc aaacttaaac caactaagcg ggtctctttg ggaaaaacac
     2761 cgagttcttt taagaaaggc aagagcttct gactggtcac aaccagatct acaggtttat
     2821 catagggata aatattatca gataagatat tgacccgtga cagttcaact ttgtaagaag
     2881 ggatagttga ggtgatgaaa ttagctataa cgttaccaac agtttcttgg ctctcaataa
     2941 cagtaatatt gattggagca atagagcttt ccaagatctg ctcaaggtat aaacacatca
     3001 agtgtaagtg accagaacta atactgcctt gacggcctgt gtcataaagc caatctttga
     3061 taacggtttc aagcttatct agtagtagca tgttgccttg atattgatca aaataataac
     3121 catcaaaggt aattaaagtt tgtaaattgt agagagttct tttgaaaaaa ggaattaagt
     3181 tagggatatg ctcatgaata tcggaatact ttccaactag tgcctgaaga cgatggatta
     3241 gtaaatgata atcgggatct ttggtgatta aatggtaaag ttgttgtcgc tgatgacttg
     3301 tccagtaccc actcaagaag gagttatcag tcgttaaata aattaaaaag agatagtcaa
     3361 aatcatcaga cgaaaatgtg acacgagttc gaggtgctag ctcatccacg gcaatggttt
     3421 tgatattgtc aaaaataggc aaggatttga gatgttcaaa aagagctaaa tgaggcaaat
     3481 gaacaggata gcgatggcgc ttccaagtca acatcaacag cacatcaaaa aacaagaagc
     3541 gtctatctaa aaaggcagaa ggttgtaagt ttttttgtgc tgcaaagata aaagcatgaa
     3601 tcgtttcaat gtctgcaggt tgtatatcat ataatataat gccgtactct ttatgtaaaa
     3661 gagcaatcaa ataccgtatt ttaagttcat ctccgataac agtattgtct acaatattta
     3721 aaccaatgtc ttgtaaataa tgttttaatt tatgaataag acgataagct tttgactggg
     3781 atatcccttg ttttcgtgta taaacagcga ttgatttgtg tttgggatta tctagtaata
     3841 agaatgtcaa catttttaga gtatctgata aggcaaaaat atcataaaaa aatgcttctc
     3901 gcttatcatt taatacctca caataaatac gagatttaat aagctcaata cgtaagtacc
     3961 ctttaaataa ggcgttaaat tgtcgaagat actgctttat ttttaaagca gtcaaagttg
     4021 tttgagaaca agctgctgcc atcgtcagtt ctttttctgt caacaaaata gccagtagga
     4081 ttttctggtc aataatatcg gattccaaat aataatctaa caatgtaatt tttctctcct
     4141 taaattaaat tgtataatcc tatatattgt agcgaatcta ccgtaaaagt caactaaaat
     4201 caataggatt accagtatag tcacaataaa gatcatcaaa aagcagcaaa cttcatcaat
     4261 agattgattg atgcgtgctt ttagctcata attgagagag ctaagaacac gcgggtgata
     4321 tcatattttt gctgttgact ttttaaattt aaaaacctaa ccagccggtt aactggtcag
     4381 gtttaaacaa gggagggcac ctacgaagat aggtgcccag gagatttatg aaaagggaaa
     4441 acaaggggaa aacctattct cccaacggtt taggtaaacc gctttttagg atgttttcat
     4501 tctacgatag taaccttaaa gttttcttaa atgattcttt agaatgcctt tatttttaat
     4561 cttttttgag agagctagtt tcttgtcagc cttgaacctt tttcctaatt tatggtatga
     4621 taagaagatg atgaaaaaag agattctcaa agaactcttc cagtctttac gaactatgga
     4681 tgtagactta aaacgtcaaa atgatcaagc tttattagtg gatgttgtta gcaatcaagc
     4741 ttatcagcgg gccaatacga ttgccaaatc aaacgattta tgatattgct gtttaggagg
     4801 tttatcttag atgacacggt tattaaaacg atatcctatt actattttcc ttttagggtt
     4861 aacaggctta atttttatag caatgcaagt ggtatatgga catttagcaa ctggtgctca
     4921 agctatttat caagttggag gtatgtttgg attactagta aaagcaatgc cagatcagtt
     4981 gtggcgattg gtgactccga tatttattca tatcggtttt ggtcattttt ttgtcaatgg
     5041 attaacacta tactttgttg gtcaaatcgt cgaagacctc tggggctcaa gccgtttttt
     5101 attactttat gttttatcag gtgttatggg caatgccttt actttttggt tgactcctga
     5161 aacagtagct gcaggagcat cgacgtcgtt atttggactt tttgctgcta ttgtagtatt
     5221 gagttttttg ggtaagaacc aagcgttgaa agatttgggc aagtcatacc aaacgttaat
     5281 tgtagtcaat ttactgatga atctttttat gccaaacgtg agtatggcag gccatattgg
     5341 cggtgtcgtg ggtggtgcgt tactgagtat agtatttcca actaagatga gagtgataac
     5401 agtgaagaaa accaagcgaa tgttggcttt agtgagctat ggtattattt tggttggtgt
     5461 gttagtgctt gggtttttat aaaaataagt gagtggttag cactgttact tctcagatgg
     5521 ctagtaggat gaaatgactc aaaaaccata aaaaataagg agggattttc cctccttatt
     5581 tttatggttt tgttttctct agtgctttgc ccagttggat gatgtaggct ttcaagtcat
     5641 ctttgacttg agggtgtttc agggcataat ccaaagaagt tttcataaac ccaaatttat
     5701 cgccaacatc atagcgtttc cctttaaact cacgagcaaa gacacgctgt gtcttattga
     5761 gggtatcaat agcatcagtc agttgaactt cattgcctgc accaggttct tgtttttcta
     5821 aaatactaaa aatttctggt gtgagcaagt aacgtccaat aattgccaaa tcactaggtg
     5881 catcttgagg ttgtggtttt tcaacaaaag tatccacact atagagtcct tttactgctt
     5941 ttgcttgagg agcaatgata ccgtagttag agacatcctc gtgaggaacc ctcatgacgg
     6001 caatagttgc agcatgagtt tcttcatagt catcgatcaa ttgtttggtt aatggtttta
     6061 catttggatt tgtaatatcc atcagatcat cacctagcat gacaacaaaa ggctcattgc
     6121 caacaaaggt ctttgcttga agaactgcgt ctcctaatcc tcttggatga ctctgtcgaa
     6181 taaagtgaag gttaatagaa gtggtctcgt ctactaactt tagaagttcg atttttcctt
     6241 tagcctgtaa attatattct aattcaaaat tagaatcaaa atgatcttct atggagcgtt
     6301 tggattttcc agtaacgata agaatttctt cgatacctga ttttagagct tcttcaacga
     6361 taaattgaat agttggttta tcaacaatag gtagcatctc cttggcaagg gccttggttg
     6421 caggtaaaaa acgtgtgcct aaacctgctg cgggaataat agcttttctg actttggtca
     6481 tcagcacctc ctcttatttt agtgacgcat ggcttaatgc cattcatttt cagaacgaaa
     6541 ttcatttgac atcatgccga ggatgctttc tttgatatca gcgccctcgt agatggactt
     6601 ataaatagct gttgtaattg gcatgtaaac tccgaggtct tgggcaattt cataggctac
     6661 cttagttgtt gcgatgcctt cgataaccat acccatgttg cgttcaatat cttctaattt
     6721 ttcaccacgt ccaagggcag ctccagctcg ccagttacgt gaatggacag aagtacctgt
     6781 tacaattaga tcaccaacac cagataaccc actgtaggtt aacgggtcag caccaagctt
     6841 gacgcctaga cgggtgattt cagctaaccc acgagtaatt accgctgctt tggcattatc
     6901 tccataccca agtccatgga gagctcctgc tccaacagca ataatgtttt tgagggcacc
     6961 agctgtttca actccgatga cgtcggtatt ggtataaagt cggaagtagt ggttactaaa
     7021 gagggactga acatactttg cagcttcaat atcttttgag gctgccgtga tgagagtaat
     7081 atcgcgaacg atagtttctt cagcatgact aggacctgat acaacgacca cttcactacg
     7141 aaaatgagct ggaatttctt cttctaggat agttgataaa cgttcgtggg tctctggttc
     7201 tagacctttt gaggcatgca tgaccactac tttatgatct aaaatggcgg caacttgtct
     7261 agcaactaat cgtgttactt tagttggcac aacaaaaagc accgcatcaa catctgatag
     7321 ggcttgacct aaatcaagag ttgccgtaat gtttttgtct aacacaatgt ctttgaagta
     7381 gtgtctattg gtatgcttgg tatttatctc ttcaatttga tcaggaatat ttccccataa
     7441 acggacgtca tggccattgt cattaagaac ctgagaaagg gcagttcccc aagaaccagg
     7501 tcctaaaata gctacttttt gttttgtcat tctaaattct ccttcaagag ctagtcactc
     7561 tattataaca taacaccttg attagctcta ttagaaaagg tatatggtct tggctaataa
     7621 ggcgttccca agagagctag ctatatttaa tgttgtttaa taagcttcat caggtgagct
     7681 gttgtcatgg ctttgccctg ttctttttag ttatttaagt tcggaaactt atttttaaaa
     7741 ataaagatat tttaattgac aatagttatc tagagaacta aaatacttat catagaaact
     7801 attaaggaaa agaaggaggg aagagatgtc acaagtgata ggtgatttac gtgaattgat
     7861 acatcaaatc gaacaaatta gtgatgagat tgcaaaaaaa tatgatgtag agcatctagc
     7921 aggtcctcaa ggttatgttc ttgttttttt agctaaacac caaaatcaag aaatatttgt
     7981 caaagatatt gaaaaacaac ttcgtatctc aaagtcagtt gctagtcatt tagtgaaacg
     8041 tatggtcaaa aatgggttta tcaatgtgat gccttcccaa gtggataagc gttataagca
     8101 agtagtgtta gcgcaggttg gtagagataa attgcctttg ttgcgggagt gtcgtaagga
     8161 tatcgagcac tattttttaa aagaaattac aaaagaagag ttgctgacag cgaaaaaagt
     8221 aattgaacag ctcaagcaaa atatgctaac ttataaagga gacaacgatg cttaaagacg
     8281 caatcttacg ttataaatgg tatgctttag gctcattttt tatggttatt ggggttgttg
     8341 caagtagtct cttgcaacca cattatctta aatctgtgct aagcgctgtg attcaaaata
     8401 atcaagagaa aatttatgag gttgggaaac cattacttat tattgccctt ttagggttaa
     8461 tgtctggagc gattaatacg gttttagctg ctaaaatagc tcaaggtgta tctgctgata
     8521 tgagggagaa gacctttcga aaaatccaag acttttcata tgccaatatt gaagctttta
     8581 atgctggtaa tcttgtggtt aggctaacta atgatatcaa tcaaatccaa agtttagtca
     8641 tgatgatgtt tcaaattctc tttcgtttgc cgttcctttt tattggcgcg tttatcatgg
     8701 cagttcagac attccctcaa ttatggtggg tcattgttgt aatggttatc ttaattgccc
     8761 tcatcatggg tttggtgatg cgtcaaatgg gtcctcgttt tggtaaattt caacggttaa
     8821 tggataagat taatcgcatc gctaaggaaa atctccgtgg cgttcgcgtg gttaaatcat
     8881 ttgtacaaga acaacaacaa tacactaaat ttaaagaaac gtccaatgat cttttggcgt
     8941 taaatttatc tattggttat ggtttttcac taatgcagcc ggctttaatg ttggtgtctt
     9001 atttggcagt ttatgtttct ataaatgttg tttcgaccat ggtcgaaaca gatccaacag
     9061 tgattgggaa tattgcctct ttcatgactt atatgatgca aattatgttt tcaattattg
     9121 tggttggttc catggggatg caagttagtc gtgcttttgt ttctatggct agaattaggc
     9181 aaatattgtc tacagaacct gccatgacat ttgaaaatga aaaggaagaa accatctcag
     9241 gaagcattgt atttgacgat gttagtttta catatcctaa tgatgatgag ccaaccttga
     9301 agcacatttc ttttgctatt gaacctgggc aaatggtcgg catcgttggt gcaacaggat
     9361 ctgggaaatc aacgcttgta cagctcatcc ctcgcttatt tgatcctcaa gatggccaaa
     9421 ttttgttagg aggaaagccg attaaaaccc taagtcaaac aaccctgcgc caatcggttt
     9481 ccatcgtgtt gcaaaaggct attctctttt caggaacgat agctgataac cttcgccaag
     9541 gctcagcaaa agctgatatt gatgctatgc aaaaagccgc tcaaatcgcg caagcaaaag
     9601 aatttattga tcgcatgaat agccgttatg agagccaagt tgaagagcga ggtagtaact
     9661 tgtctggcgg acaaaagcaa cgtctgtcta ttgcacgtgg tgtcattaat catcccaaaa
     9721 tccttatatt agacgattcc acttcagctc ttgatgcaaa atctgaaaaa cgcgttcaag
     9781 aagccttaag tcataaatta gaaggtacaa ctacagttat tgttgctcaa aaaatttcat
     9841 cggtagttaa ggcagataag atcttagtcc ttgaccaagg acagttaatt ggagaaggaa
     9901 cacacgcaga gttggtggct aataatgcga tttatcgtga aatttatgag acacaaaaag
     9961 gaagggagga gtagtgatga aaacaggacg ttttttctgg ttttatttta aacgctatcg
    10021 tttctcattt actgtcattg ctgttgccgt tatcttagca acttatttac aagtaaaagc
    10081 tcctgtcttc ttaggagagt ccttgactga gttgggaaaa atcggtcagg cttattacgt
    10141 tgctaagatg agtggtcaga cacattttag ccctgattta tcagctttta atgccgtgat
    10201 gtttaagctt ttgatgactt atttctttac tgttttagct aatctaatat atagtttctt
    10261 acttacacgt gttgtctcac attcgactaa tcgcatgcgc aagggcttgt ttggtaaatt
    10321 agaacgttta accgtcgcct tttttgaccg ccataaagat ggggagattc tttctcgttt
    10381 cacgagtgat ttggataata ttcaaaactc gctgaaccaa tccttggttc aagtggtgac
    10441 taatattgcc ctttacatcg gcctggtctg gatgatgttt aggcaagata gccgtttagc
    10501 tttgttaacc atcgcatcaa ccccagttgc tctcattttt ttagtgatta acatccgttt
    10561 ggcaagaaaa tacaccaata ttcaacagca agaagtcagt gctttaaatg cttttatgga
    10621 tgaaaccatt tcaggacaaa aggctattat tgtacaaggt gtccaagaag atacggtgac
    10681 agccttttta aaacataacg aaagggttcg acaagccacc ttcaaacgcc gtctgttctc
    10741 aggacaatta tttccagtca tgaatggaat gagccttatt aacacggcta tcgtgatttt
    10801 tgtcggttca acaattgtcc tcagtgacaa atctatgcca gcagcggcag cgcttggttt
    10861 agtggttact tttgtacaat attcccagca atattaccaa cccatgatgc aaatcgcgtc
    10921 tagttgggga gaattgcagc tggcctttac cggtgctcat cgtattcaag aaatgtttga
    10981 tgaaaccgaa gaagttcgtc cacaaaatgc accagcgttc accagcttaa aagaagcagt
    11041 ggcgattaac cacgtcgatt ttgggtatct tcctgggcaa aaagttttat cagatgtgtc
    11101 aatcgttgca cccaagggca aaatgattgc cgtggttgga ccgacaggtt ctggaaagac
    11161 cactattatg aacttgatta accgtttcta cgatgtggat gcaggttcga ttacctttga
    11221 tggccgtgat attcgtgact acgatttgga tagtcttcgt caaaaggtag ggattgtgtt
    11281 gcaagagtca gttctttttt caggaaccat tacggataat attcgttttg gtgatcagac
    11341 cattagtcaa gacatggttg aaactgctgc gcgtgcgacc catattcatg actttatcat
    11401 gtccttacca aaagggtaca atacctatgt ctcagatgat gacaatgcct tttcaacagg
    11461 tcaaaagcag ttgatttcta ttgctaggac gctactgaca gaccctgaag tgttgatttt
    11521 ggatgaggcc acttcaaatg ttgatacggt taccgaaagt aaaattcaac gggccatgga
    11581 agctatcgtg gcaggtcgaa ccagctttgt cattgctcac cgcctcaaaa ccattttaaa
    11641 tgccgatcac attattgtgt tgaaagatgg caaggtcatt gagcaaggaa atcatcatga
    11701 gctattgcat caaaaaggct tttacgccga attgtatcac aatcaatttg tctttgaata
    11761 gatggtatca gctccgcgtc ttagcggagt tttttggtga acaataaagc agtcaagctt
    11821 tctttcctga tatggtataa tagcaagcaa gagaaaaaac aattagaaag tagccacaat
    11881 gattgattta caagagattc tcgctaacat gaatcccaat caaaagataa attatgacag
    11941 ggtcatgcaa cagatggcca aggtttggga gaaggaatcc gtgcgtccca gtattttaat
    12001 gcatgtctgc tgcgccccat gctccactta caccctagaa tacctgacgc agtttgctga
    12061 cattacggtt tactttgcca attctaatat tcaccctaag gacgaatacc atcgcagagc
    12121 ttatgtgaca caacagtttg tctccgagtt caacgctaaa acaggcaata ctgttcagtt
    12181 tctcgaagcg gactatgtcc ccaatgagta cgttcgacaa gtgcgaggct tagaagaaga
    12241 accagaaggt ggggaccgtt gccgtgtctg ttttgattac cgactagaca agaccgctca
    12301 aaaagcagtg gaactaggtt ttgactactt tgccagtgcc ctaaccatca gtcctcataa
    12361 aaattcgcaa accattaatg atgtgggcat cgatgtgcaa aaggtttaca ccaccaaata
    12421 cctgccaagt gatttcaaga aaaacaatgg ttatcgcaga tccgttgaaa tgtgtgagga
    12481 gtatgatatt taccgccaat gctattgtgg ctgtgtctat gctgccaaaa tgcaaggtat
    12541 tgacttggtt caagtgaaaa aagatgccaa agcttttatg gcagacaagg atttggataa
    12601 tgatttcacc cacatccgct ttagttatcg tggggatgag atgtgatggc atgattaaaa
    12661 gtggtccgtt taaagttgac cgcttttttg ctattctttt acgaatagtc tataataaga
    12721 ggatatgatt gacttgaaag gatataccta tcataatgac aaaaattcgt ggtttcgagc
    12781 ttgtttcaag ctttactaat cctgatttac taccaaaacg tgagacgact catgcagctg
    12841 gttatgacct gtctgttgct gaggctgtaa ccattgcccc aggggagatt aagttggtac
    12901 caacaggggt taaggcctat atgcaagatg gcgaggtgct ttacctctat gatcgttcgt
    12961 caaatccacg aaaaaaaggg attatcctga ttaattcagt aggtgtgatt gatgcagatt
    13021 attatggtaa tgaggctaat gaaggacata tttttgcaca aatgcaaaac attacagatc
    13081 accctgtgac attagctgtg ggtgagagga tcgttcaggg ggtttttatg ccttttttaa
    13141 ttgctgatgg tgaccaagcc agaggtgaac gaacaggtgg ttttggttcg acagggcagt
    13201 aaagcgattt aacaaaaatg cttatgacag cagacctatt ctttaagagt gggtttgtct
    13261 tgtctagggg agggagatta ctatggcaaa gaaaaaagca acctttatct gtcaggagtg
    13321 tggctaccag tcgccaaagt atttagggcg ctgtccaaat tgctcggcct ggtcttcttt
    13381 tgtggaagaa gtagaggtca aagaagtcaa aaatgcccgt gttagtctag ctggagaaaa
    13441 gtccagaccg gttaaactaa aagatgtgga taatattagt tatcacagaa cacagactga
    13501 catgtctgaa tttaatagag ttcttggagg gggtgtggtt cctggaagct tgattttaat
    13561 tggtggtgat ccaggtattg gaaaatccac cttactcttg caggtatcca cgcagctcgc
    13621 taataaggga acggttctct atgtgtctgg ggaagaatca gcagagcaga ttaaactgcg
    13681 gagtgagcgt ctgggggata ttgacaatga attttacctc tatgccgaaa ccaatatgca
    13741 agctattcgc acagaaattg aaaatattaa accagatttt ttaattattg actccattca
    13801 gaccatcatg agccctgata ttacaggtgt tcaaggatca gtcagtcagg tgagagaagt
    13861 cactgcagaa ttgatgcagc ttgcaaagac gaacaacatt gcaaccttta ttgtgggtca
    13921 tgtcaccaag gaaggaacct tggctggacc tcgtatgtta gaacacatgg tggataccgt
    13981 tctctacttt gaaggggaaa ggcatcacac ctttcgcatt ctgcgggctg tgaaaaaccg
    14041 ctttggctcc actaatgaga ttggcatctt tgaaatgcag tctggcggct tggtagaggt
    14101 cttaaatcct agtcaagtct ttttagagga acgcttagat ggggcaacag gatcggctgt
    14161 cgttgtaacg atggaaggaa gtcgtcctat cttagcagag gtgcaatctt tagtgacacc
    14221 aaccgttttt ggcaatgcca gacgaaccac tacgggactt gatttcaatc gcgtaagcct
    14281 aataatggca gttttagaaa agcgctgtgg tttactctta caaaatcaag atgcctacct
    14341 caagtcggct ggtggtgtca aactagacga acctgccatt gatttggcag tcgctgtggc
    14401 tatcgcatcc agttataagg aaaaaccaac cagccctcaa gaagctttct taggcgagat
    14461 cgggttaaca ggtgagattc ggcgagtgac ccgtattgag caacggatta atgaagcagc
    14521 aaagcttgga tttaccaagg tctatgctcc taaaaatgcc ttgcaaggca ttgatatccc
    14581 tcaaggtatt gaggttgtcg gagtgactac ggttggtcag gttttaaatg cagtttttag
    14641 ctagaggatc agaaactaag agcaaatgag gaggaaattt gtcaagaaag tatcccaatc
    14701 atttgttttt ttaacttttc gaacgatacc gaccgtctaa gaggttaatc cagctatttt
    14761 ccataaaaga tgttaagata agacaaacta acagcaaaaa tagctctgct gtttctcaaa
    14821 aggagtttat tgatgtctta ttttgaacat tttatggctg ccaatcaggc ttatgtggcc
    14881 ttgcatggga cagctcattt gcccttaaaa cccaagacta aagtagcgat tgtgacttgt
    14941 atggattcac ggctacatgt ggcccaagct ctggggctgg ctctaggaga tgctcatatt
    15001 ttaaggaatg ctggcggacg tgtcaccgaa gacatgattc ggtcgctggt tatttctcag
    15061 cagcaaatgg gaacgcgaga gattgtggtt ctccaccata cagattgtgg cgcgcagact
    15121 tttactaatg aaggctttgc caagcatatt catgagcact taggtgtgga tgtttcaggg
    15181 caagatttcc ttcccttcca agatgtggaa gacagtgtcc gcgaggatat ggctaagcta
    15241 agagcctcct ctcttatccc tgatgatgtc gttattaacg gtgccgtcta cgatgtggat
    15301 actggaaaga tgacacaagt aatggaataa tgagtagcca agttgcagag ctgaattcag
    15361 ctctttttta tttttaaaaa ttattgaaaa tattagacaa agaaataggg aagcgttata
    15421 ataattgtat caagttattc atacaaacaa ggagagtaag atggtcgaca atagaatgag
    15481 atttacgatt gatcaaaaca tgcaatttcc actagttgag attgatctgg aacatggggg
    15541 atcagtttac ttacaacaag gaagtatggt ttaccatact gagaatgtaa ccttgaatac
    15601 caaattgaat ggtaagggat ctggtttagg aaaattagtt ggagccatcg gccgttccat
    15661 ggtttctggt gaatcaatgt tcattacaca agctatgtca aatggagatg gtaaattggc
    15721 attagcaccc aatacaccag gacagattgt tgctttagaa ctaggtgaaa aacaatatcg
    15781 tctaaatgat ggtgcctttc tagccctaga tggttcagca cagtacaaaa tggaacgtca
    15841 aaatattgga aaagcacttt ttggtggtca aggcggactt tttgtcatga caactgaagg
    15901 ccttggtacc ttacttgcta actcgtttgg atctatcaag aaaatcacac ttgatggtgg
    15961 cacaatgact attgataatg cccatgttgt agcatggagc agagaacttg attatgatat
    16021 tcatttagaa aatggcttta tgcagtcaat tggtacaggt gaaggagttg ttaatacctt
    16081 tagaggtcat ggtgagattt atatccaaag tcttaacctt gagcaatttg ctgggactct
    16141 taaacgttat ctaccaacta gttcaaatta gtcaaaataa cataaaatca gctttttggg
    16201 gctgattttt ttcgcctaag caagtaaaat atgctataat aagaaagatt ttagaagaag
    16261 tctgaaaagg tcttggcaag ctcaaatcat catttgttgc ttgtttttcg tgccacaggt
    16321 ttctgagtga tatatgtaac aggagaagaa gcatgtctaa accaattcgt gtgcgttatg
    16381 caccaagtcc aacagggctt ttacatatcg ggaatgcccg cacagcccta tttaattacc
    16441 tttatgcccg tcgtcacgga ggtactttta tcattcgtat tgaagatact gaccgtaaac
    16501 gtcatgttga agatggtgaa cgttctcaac ttgaaaacct aaaatggtta ggaatggatt
    16561 gggatgaaag cccagaaacg catgaaaatt accgccagtc tgaacgtcta gcactttatc
    16621 aacaatatat tgatcaattg ttagctgaag gaaaagccta caagtcttac gtgactgagg
    16681 aagaattggc agcagagcgt gaacgccaag aagcagctgg cgaaacgcct cgctatatca
    16741 atgaatttat tggtatgtca gctgacgaaa aagctaagta cattgctgag cgtgaagcag
    16801 caggtatcgt tccaacagtc cgtcttgctg ttaatgagtc cggtatttac aaatggactg
    16861 acatggttaa aggcgatatc gagtttgaag gtggcaacat cggtggtgac tgggttattc
    16921 aaaagaaaga tggctaccca acttataact ttgccgttgt tgttgatgat catgatatgc
    16981 aaatttctca cgttatccgt ggcgatgacc atattgccaa tacgccaaaa caattgatgg
    17041 tctatgaagc tcttggctgg gaagcgccag agtttggtca tatgactctt atcatcaatt
    17101 ctgaaacggg taaaaaatta tcaaaacgcg acaccaatac cctccaattc attgaagatt
    17161 accgcaaaaa aggttatatg cctgaagctg tctttaactt catcgccctt cttggctgga
    17221 atcctggcgg agaagaggaa atcttctctc gtgagcaact gattgccctt tttgatgaaa
    17281 atcgccttag caagtcgcca gctgcctttg accagaagaa aatggattgg atgagcaatg
    17341 agtatcttaa acatgcggat tttgaaacag tttatgccct ctgcaaacca ttccttgaag
    17401 aggcaggccg tttgacagaa aaagctgaga agctagtaga attatacaaa cctcaattaa
    17461 aatctgcaga tgagattatt ccattgactg accttttctt ttctgatttc cctgaattaa
    17521 cagaagccga aaaagaagtg atggcaggtg aaacagtttc gacagtcttg caagctttca
    17581 aggctaagtt ggaagctatg tcagatgaag acttcaaacc agaaaatatt ttcccacaaa
    17641 ttaaggctgt tcaaaaagaa acaggaatca aagggaaaaa cctctttatg cctattcgta
    17701 ttgcagtatc tggtgaaatg catggcccag aattaccaaa tacgatttat ttattgggac
    17761 gtgataaatc cattgagcac atcaaaaaca tgctataagg ctgtatcgtt cacctttatt
    17821 tttaaacgct ttaaggagtt aaaaagtcac gacaacgaaa gattgaagat taagttcttc
    17881 agtctttttt atcgttatct gagcttgcta ccttggtaaa gtaaaaaata gtatagttta
    17941 tttctatttt ggagattgga tttgaaagag aggtggtgag atgcttacgt gataatgaca
    18001 gcaaacggtg aggttttgat tagtgtgatt taaagaaatg gtttttatga atcaattagt
    18061 gtacaatatt tttttggtat atgctgaaag agactagttt agtattcact tagctaatca
    18121 attgtaatca aataatattg taatcattgt cataaaatat gctaaaataa taaagttgga
    18181 aaggagaaaa aaatggctaa tagcgaatat atgtttttat tattatcaat tattgtctat
    18241 tatatgacaa aaatttatat tttttccttt ctatctgata tcacattacc agtttggaaa
    18301 caactaacga ttttggcttt agccctattt ttcaatcagt tcccgtattt gtcgccattg
    18361 ctaattgatc ctctattatt tttagttgtt ttaaggcaag aaaccaagca attattttct
    18421 ttgaaagctc tttttttggc tgttgcacct agtgttttgg tggatttgct atctcggttt
    18481 atgggtacaa tcgttatccc ctatcttttt ttgtcgagtg gtatttatct gggtcatatt
    18541 atttttgact tacttgctta tctgctgatt tttccaagtt ttgctattat taattatatg
    18601 attggaaaag attacaagat gatatgccaa tccggatatt cgaaacgatc gcataatttt
    18661 tatcaaacat tgctgatttt tgttttggtt tattatgtgg acatttttgt cattttagga
    18721 tttacggacc cctttttaca ttttcatcat tctctttttg ttcccacacc ttataagtta
    18781 ttgtttttga tgtttatact tcttttagtt tatcttctat cttattttaa tcatagttct
    18841 aaagaatacc ttaaaaatga gttgagaaga gaacaacaag cttatatgac taacttagag
    18901 atttatggga aacatcttga gaaactctat cgagatgtaa gagcttttca aagtgattac
    18961 ctgagccgta tagagcgttt aggtcaagcc attaagagtg aatccattac tcagattcaa
    19021 gatatttatg cccaaacggt tcatgaagct aacgactact gggatgataa acactataat
    19081 atctcgaagc ttaggaaaat taatatctca tcgattaaga gcttattgtc agctaaaatt
    19141 atcagtgcgg aaaaatcagg tattgatttg aatgtggaag tgccagataa tataaaagag
    19201 acttacattc ctgagttgga cttactattg ttgatgtcta ttttttgtga taacgccatt
    19261 gaggcagctc ttgaagcaca acaacctcat atgtcaattg cttacttttt gttagatgac
    19321 tatcagatgt ttgttgtgac aaatacgact aaaaaaaagg tagacattaa caagatcttt
    19381 gaagaaggct attcttcaaa aggttcagaa cgtggtatcg gcctttctaa tgcgcagcgt
    19441 attctcaaaa agtatcctta tttatccttg cggactaaaa gttttgataa ggaatttagc
    19501 caaaccttga ccatgccaaa ggaggaggtg gatagatgat ggttatatac agtatggctt
    19561 tattctatgc taccatcttt attaacagct gggtcatttt tgcaaaggtt tctgctatta
    19621 aactaagctg gaaacgggtt agcattatag gcattagttt tgtaattgct aatatgatat
    19681 ttgacaaagt cattttgatt gaccaactgt tctttattat tgttagtttg ttaagtgctc
    19741 cgaaaaagaa attatttgag catatgttta atggtttctt tactatcttg attgtcgaat
    19801 tactgtttcg cgtcatcgga tctttctttt taccagctgt cttaggattt agcattggtc
    19861 aaattaataa taaccttaag cttttagagt tatgttatct ttttgtatta ccaatatttt
    19921 atctgtttag ctacattttc agtattgact taagcttaat aaggtttatc agtgaagata
    19981 agatgaaaaa gtgggtattt tggatgaata ctgccatgtt ttcttactac tttttcgccc
    20041 attttttggt aactgtgcaa agcggatttc ttgcactata tttccagtac cggtctattt
    20101 tagtatttat ttatttagct atttttattt gggttattgt gaaattagat cgatttgcta
    20161 aagatcagct gtcacaaaaa ttaacacaag cacaaaatga acgtattgcg tatcttgaaa
    20221 attacaatca atcgattgag caactttacc gagaaatcag aacagttaaa catgattctg
    20281 aaaatatttt aattagttta aaagatagta tcgatagtgg tgatatagat ctgattacta
    20341 gagtttatga cacggttatt cagcaatcgg caacttctat gatgcgcaca aattatgaaa
    20401 tatcttcttt agacaatatc aaagaggctg tgattcgcag catcatgaat tccaaattgc
    20461 ttgaagctca gtatttgggt attgaacttt atattgagat tccagatgtt atcgatcatt
    20521 tacctattaa gttaatcgac ttaattgtac tttttactgg actagtggac aatgctattg
    20581 agacagccaa aggcagtaga cgtccttttt tatctattgc atactttaaa caagataaca
    20641 agcaattatt tattattgaa aatagcacaa aaaccaatcg tgtggatata gccaaacgct
    20701 ttgatgctca gcagcagaac tcagcccact ttttgactgt tttagatagt tacccccaaa
    20761 taacgctttc gactaaaagt gaccattatc gattaagaca attgttagaa atgagataaa
    20821 gtatgatgaa catttttatt cttgaggatg attttatcca gcagacacgc atagaatcta
    20881 tcgtagtagg catcttaaaa gagactagaa taccatgtaa tcagcttgaa gtgttctcga
    20941 ctcctcaaaa attatttgag agtatccaag aaagaggaga ccatcagctg tattttttag
    21001 atattgaaat tggtgaatat actcgttgtg ggcttgaatt agctgcagct attcgacaaa
    21061 aagatcctaa tgccgttatt gtgtttgtca ccactcattc agaatttgct cctatttctt
    21121 ttaaatataa ggtatccgct ctagatttta ttgataaagc aggtggtcaa aaacagttta
    21181 aagaacaaat cgaagaatgt atccgatata cttacgatat gatgtctagt cgtgagtcaa
    21241 aggacatgtt tttatttgag actccacaga caagattaaa attgccttat aaggatattt
    21301 tatactttgc tacagccaca actcctcaca aagtttgttt atggactcag acagaaagat
    21361 tagagtttta tggtaatcta tctgagattc aagcagtagc accgaaactt tttttgtgcc
    21421 atagatccta ccttgtgaat ctagataagg ttgttcgaat tgataagagt aagcagctcc
    21481 tttatttcga aaatggtgat tcttgtatgg tatcacggtt aaaaatgaaa tgtctgtttg
    21541 aacggtggga ggctcttcgc taaagttaag agagcaataa cattttagga tgaaaaagca
    21601 acatttcagg aaatgatgct cttattgaaa catttttcgc tataataatt agtgtaaata
    21661 aagatttacg aagtcatgag tttatcgagc aatcaatccc caattcaatc aaaatattgt
    21721 tttctctctc tccataaaca aatagtattt ttgatatgat ggctcggcag acaaaatgac
    21781 gatgtcagtt gtctttgttt ggatatcaca ttagctggtt gtaaaatcag tattaaagcc
    21841 cggcttgccg ggttttttga taggtaaata cagggataag tagctgacgt cttgtggatt
    21901 ctgacttttt atggttgttt tctgaaggtt attcctttgt cgaaagaaga actatactac
    21961 gaaaagatgg agtgacaaga ggcagttgaa gcacaaaaac tagaaatagt acagaaagag
    22021 gcttaatctg aaagggttag ggctttttaa ttttttaggg gatgtggtat aatggtaata
    22081 atttagatat tggagttaaa ttttgaagaa gacctatcgt gtcaagcgtg agaaagattt
    22141 ccaagccata tttaaggatg gaaaaagtac agcaaatcga aaatttgtca tttatcattt
    22201 aaatagaggc caagaccatt tccgtgtggg tatttctgtc ggtaaaaaaa taggaaatgc
    22261 agtcaccaga aatgcagtca aacgaaagat acgtcatgtt atcatggcat tagggtatca
    22321 gctgaagtca gaggatttcg tggtgattgc ccgtaagggt gtcgagtctt tggagtatca
    22381 agagcttcaa caaaatttac atcatgtttt aaagttagca caattgcttg agaaaggttt
    22441 tgagagtgaa gaaaaacatt aaaattgcaa gaatagtccc cttagttcta ttattagtgg
    22501 cctgtggtcg tggtgaggta acggcacaat catctagtgg ttgggaccag ttggtttact
    22561 tatttgccag agcaattcaa tggctttcct ttgatggttc aattggtgtt ggcattattc
    22621 tttttaccct tactatccgt ctcatgctca tgcctttgtt taatatgcaa atcaaatcaa
    22681 gccagaagat gcaagacatc caacctgagc ttagagaatt gcaaaagaaa tacgctggta
    22741 aagacacaca aacgcggatg aagttggctg aagaaagtca agccctttac aaaaaatatg
    22801 gggtcaaccc ttatgctagc ctcttacccc tcttaattca gatgccagtt atgattgccc
    22861 tattccaagc cttgacacgg gtatctttct taaaaacagg gactttcttg tgggtggaat
    22921 tggcacaaca tgatcatttg taccttttac cagttttggc agctgtcttc actttcttgt
    22981 ccacttggtt gaccaatcta gcggctaaag aaaaaaatgt catgatgact gttatgattt
    23041 atgtgatgcc gctaatgatc tttttcatgg gctttaactt ggctagtgga gtagtgctct
    23101 attggacggt ctcaaacgcc tttcaagtgg tacaactact gttattaaac aatcctttta
    23161 agattattgc cgaaagacag cgtcttgcca atgaagaaaa agaacgccgt cttcgtgaac
    23221 gtcgtgctcg taaaaaagca atgaagagaa aataggagtt taggttatgg tattatttac
    23281 aggaaaaaca gtcgaagaag ctatcgaaac aggacttcaa gagttagggt tatcacgcct
    23341 taaagcgcat atcaaagtca tttcaaaaga gaaaaaaggt ttcctcgggt ttggtaaaaa
    23401 gccagcccaa gttgatatcg aaggtatcag cgacaagacg gtttataagg ctgataaaaa
    23461 agccactcga ggtgttccag aggatattaa tcaaaaaaat gctcccgcgg tcaattctgc
    23521 tgatgtagaa cctgaagaaa taaaagccac tcaaaagtta gaagcagaag ataccaaagt
    23581 tgttcctctc atgtctgaag atagtccagc gcaaacccct tctaatcttg ctgagacagt
    23641 cactgaaaca aaagcacaac aaccgtcaat cccagtcgaa gaatcagaag tgccccaaga
    23701 tgctggtaat gatggtttca gcaaagatat tgaaaaagct gctcaggaag tgtccgatta
    23761 tgtgactaaa atcatctatg aaatggatat cgaagccacc gttgaaacca gcaacaatcg
    23821 tcgccaaatc aatttgcaga ttgaaacgcc agaggcggga cgtgtgattg gttaccatgg
    23881 taaggttttg aaatccttgc agttgttagc tcaaaatttc ttgcacgacc gctattcaaa
    23941 aaatttttca gtatccttga atgtccatga ttatgtggaa catcgaacag aaaccttgat
    24001 tgactttacg caaaaagttg ccaaacgcgt cttggaatct ggtcaagatt acactatgga
    24061 tcccatgagt aacagtgagc gtaaaaccgt tcataaaacc gtttcaacca ttgaaggggt
    24121 tgaaagttat tctgaaggca atgatcctaa ccgttatgtg gtagtcagtc ttcaacgtta
    24181 gatcctaaaa agaatcttcg gtagttagtt caactatcga agattttttg tatagccagc
    24241 ttaaccgttt gttttactga tctcattgat tattgttgct attgataagg tttcaacggt
    24301 aaggcaaagg aacagtgtca aagaagacac actttatgaa atgagcggcc tcttaaatga
    24361 gagagaaact gttgaaaaac gaaaataaat cttgacagta gaccctcttt aagatagaat
    24421 attatagtat gtttagtaac tgatatcaca aatagccggc taaacgaata caaaatctat
    24481 gaggaggtat tcactgtgaa acgtacttat caaccaagta aaatccgtcg tcaacgtaaa
    24541 cacggattcc gtcaccgtat gtcaactaaa aacggacgtc gcgtgcttgc tgcacgtcgt
    24601 cgtaaaggac gtaaagtatt atcagcttaa ttgcaaaaaa tacaactaaa gtaaaccaag
    24661 agtgctcgag gctcttggtt ttttaacgtt ttctaatcgg aaatttgtaa tgtataagta
    24721 tggtgtcaac tccttacctt cttatttgtt gtatg
//
LOCUS       DATTYN010000030        24665 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.30, whole genome shotgun sequence.
ACCESSION   DATTYN010000030 DATTYN010000000
VERSION     DATTYN010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24665
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.30"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            89..1633
                     /locus_tag="VB649_001455"
     CDS             89..1633
                     /locus_tag="VB649_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP1670402.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNTSTNIYLFAFMFITY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGIMIDKTDTKFGKYRPILIAGNIITAL
                     SLILLLALNNVSEGMRFPLFILVLIVHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAVMLTTLMTGGQFVVSGFLVPKFGNFTLEFFNVLIYGTIVISAILGLLAVIGIWSKD
                     NKEYFGLGENTQKTELKDYMKVIKGNKPLQVLSIAAALVKFSVQFFGDSVVMVMLYGI
                     VFGNYALSGQFSLLFVIPGVLINILISSVARKKGLRFSYVASLQFGLIALAAFGVVLY
                     FGKVGDLSLSNINLYTICFIITYMLARYITQAPAGLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVVGAVLATIGFAKAFPTMETPLTPELKMATIILLVGIPF
                     VALSVALFLMRFYKLDKEEMVRIQEKIQVMKAASSKERVKDIARNVPLSDMDYVDVTK
                     YPVDKD"
     gene            1786..2814
                     /locus_tag="VB649_001456"
     CDS             1786..2814
                     /locus_tag="VB649_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEP1670403.1"
                     /translation="MKTVVSLGEILLRLSPPQYQTLTQATSLECQFGGSELNVLSTLA
                     QLGHKVSLISAIPANDLGRMTKTFLFSRQISQDYIIEKGQRLGIYYYQKGFSLRASRV
                     TYDRKYSAFWESELADYELADVFAGADWFHVSGITPALTDKLYHLTHYLMTKAKTEGL
                     KVSFDLNFRASLWDSFQEARELLSPLVALADVCIGIEPLVLAGDGEKDLKDQLGLSRP
                     YEDQALLENVLSKLAKTYGVTSFAFTQREMGHTNEYLLKGYLYQDGNLYQTDKSGIQV
                     LDRVGTGDAFTAGLIHGMLQKEAPDKALAIAMASFKFKHTIEGDSNIITPADIDYLIT
                     DASHEIKR"
     gene            2838..4628
                     /gene="uidA"
                     /locus_tag="VB649_001457"
     CDS             2838..4628
                     /gene="uidA"
                     /locus_tag="VB649_001457"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEP1670404.1"
                     /translation="MLYPTLTKTRSLYDLSGLWQFKLGDHNPEDCLSTEDVMVVPTSF
                     NDVVVDTDKRNYIGDFWYERLVDLPKLAKDDELILRFGSVTHNAIVYVNGRELASHKG
                     GFTPFEVVVPEDLYQDHQIRISVRANNILDYSTLPVGNYSEERQEDGSMKKVVKENFD
                     FFNYAGIHRPVKLVARPKTHISDITITSDLSDDLKTADLSIAVETSAAVDAIQVTILD
                     EERQVVGQTNDGHVKLDCVHLWEVLDAYLYTARIEISVDGKIVDTYEEPFGVRSVHVA
                     DGQFFVNHKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKEIGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEIPAVGLFQNFTASLDLTPKDMGTWSVMETKEAHEQAIQELVK
                     RDKNHPSVVMWVVANEPASHEAGAHDYFEPLVALYKELDPQKRPVTLVNIFMATPDRD
                     EVMDLVDVICLNRYYAWYVDHGDLAKGEAGLRKELLEWQSKFPDKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCDFYAMTHGVFDEIPNLVGEQVWNFADFETNLMIFRVQGNHKG
                     LFSRNRQPKQVVREFKKRWTAIPNYNYKKK"
     gene            4670..5341
                     /locus_tag="VB649_001458"
     CDS             4670..5341
                     /locus_tag="VB649_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEP1670405.1"
                     /translation="MARPLVEKTAERLLQLILERGYDVGAKLPNEYELAQDLDVGRST
                     IREAVRSLATRNVLEVRQGSGTYVSSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALAAQNATPKEIKELEKIVVEIEEAVTAGDPKHLQLDVTFHSMMAKFSGNIAMD
                     SLLPVINKSIHLINANYTNRQMKEDSLQAHRDILTAIKERNPIAAHDAMLLHIMTVKR
                     TAFLP"
     gene            5469..6086
                     /locus_tag="VB649_001459"
     CDS             5469..6086
                     /locus_tag="VB649_001459"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HEP1670406.1"
                     /translation="MLTQLKENYFFAVVRGKTAEDAIEIAKYAVLGGIRNIEITYSTP
                     NASEVISKLSDDFKDDTSVVIGAGTVMTTELAKEAIAAGAKFLVSPHFSKEIADIANQ
                     EGNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPSFIKDIHGPIPEVDLMPSGGVS
                     VDNVKEWKNAGAVAVGVGSALASKVATEGYDSVTRIAQSFVSALD"
     gene            6116..7513
                     /gene="uxaC"
                     /locus_tag="VB649_001460"
     CDS             6116..7513
                     /gene="uxaC"
                     /locus_tag="VB649_001460"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEP1670407.1"
                     /translation="MTFNDANFMLKNEAAKKLYQQIQDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLERSYGNPVYHWS
                     AMELKNVFGVEELLTQDNAEEIYHRLNAYLVDHKISPRKLIADSKVTFIGTTDHPLDD
                     LEWHQQLADDSTFETVVAPTFRPDEAFVEHRNFAQFVVRLGTSTGSRITDFTTFMAAM
                     EKRIAYFAEKGCKASDISFAEIVFEKATPEALNQIMAQVLAGDTPSQLDINQWQTAVF
                     ADLCRLYKQYGFVTQVHFGALRNNHSDIFKRLGADVGVDSLGDQTALTSNMNRLLDNL
                     VQTDSLPKMIWYNLNPSYNIAVANTLANFQANEAGVASYLQFGAGWWFADTKLGMISQ
                     MNALAEQGMLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQAIGQ
                     MTKDIAYDNAVRYFN"
     gene            7608..8702
                     /locus_tag="VB649_001461"
     CDS             7608..8702
                     /locus_tag="VB649_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEP1670408.1"
                     /translation="MKMSFRWYGKQDPVSLEEIKAIPGMQGIVTAIYDVPVGQAWPHE
                     NILALKKMVEDAGLEISVIESIPVHEDIKQGKPTRDALIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNHPLPDGSTSLAFLKADLEGVDPVADDLNLPGWDSSYSKEEMKA
                     IIENYRNNISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQD
                     AVERFLNLYDSPNNGITMCVGSYASDPKNDVIAMTEYALKRNRINFMHTRNVTVGAWG
                     FQETAHLSQAGDIDMNAVVKLLVDYDWKGALRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKTPDFGITVKTVGDK"
     gene            8717..9556
                     /locus_tag="VB649_001462"
     CDS             8717..9556
                     /locus_tag="VB649_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEP1670409.1"
                     /translation="MTRVIDFKDKVVIVTGAGGVLCGYMAKEFAKAGAKVALLDLNQE
                     AAQAFVTEIEAEGGVAKAYKANVLSKENLEEVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHEVGLPEETKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRGLLF
                     TEEGQPTARAEKILNNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            9825..10628
                     /locus_tag="VB649_001463"
     CDS             9825..10628
                     /locus_tag="VB649_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEP1670410.1"
                     /translation="MTTKKEAFVFCVDSDGCAMDTMTYKHQLFFGPIAAEVFGVTNRE
                     VFLKEWDHVNLYSRTRGVNRFVGLVMGLDYAGLKGIDRLKDWVANTKSLSNASLEAEL
                     AKEASDDLQKALEWSNEVNRQIKAYEGEALAFPGAESGLEKLHQLGKVFVVSSANKEA
                     VEEEWHDQGLMAHVDDLYCQDCGKKEDVIAELLQKGYQKERLMMVGDSPGDLAAAEQN
                     QVAFFPILVGKEAQSWADLKEAVADAFVTGELSDLDFNSLKETFWHNLD"
     gene            10745..12535
                     /locus_tag="VB649_001464"
     CDS             10745..12535
                     /locus_tag="VB649_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEP1670411.1"
                     /translation="MTHLVDLRKKPYHLDDQAIAWVEETIASMSLEEKIGQLFVNMGA
                     SRTEEYLTQVLNDYKIAAVRYNKGMADEVWEQNYILQTKSKIPLLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGIEAAAVGCNASFAPIVDLTRNWCNPIIAS
                     RNWGSNVDQIITFSKEYMRGIMEHGIMPFAKHFPGDGIDERDHHLSFASNPMTKDEWM
                     STFGRIYGELTEAGLPGIMAGHIHLPNVEKEMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLMLPTAVEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILTEERLHDALRRTLGLKARLGLHLYEGRREEIMLPKEEAMTLINTKEAQAIADEVAD
                     KAITLVKDKQKDIFPVTPERYKRILIVNVEGYKGGFGAMIAGQKKRASDVVKELLEAR
                     GHDVTVWESTEERIMQLPESERAAAIANIYAQKQPISNLTDHYDLILNLVDVNSGGTV
                     QRIVWPAAKGTPDQPFYVHEIPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     EKLASESNFTGVSPVDAFCGLIDTHLWREY"
     gene            12581..13644
                     /locus_tag="VB649_001465"
                     /pseudo
     CDS             12581..13644
                     /locus_tag="VB649_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137776.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13908..14321
                     /locus_tag="VB649_001466"
     CDS             13908..14321
                     /locus_tag="VB649_001466"
                     /inference="COORDINATES: protein motif:HMM:NF013537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670412.1"
                     /translation="MGTAVAYTEEIPTTPILTLEVTERREAINKINRLSDQYPNDPEI
                     QATLEDTTNKILAFESADITEALIAEVNSEVTRLNEEKIARDAVDTAEKADAEKRHDF
                     LKQQDAVVIAIQELANIPAEKAFRQYANDNGVDDV"
     gene            14442..14633
                     /gene="grab"
                     /locus_tag="VB649_001467"
                     /pseudo
     CDS             14442..14633
                     /gene="grab"
                     /locus_tag="VB649_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G-related alpha2-macroglobulin-binding protein
                     GRAB"
     gene            14871..15413
                     /locus_tag="VB649_001468"
     CDS             14871..15413
                     /locus_tag="VB649_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEP1670413.1"
                     /translation="MDIWTKLAVFAFFETPKVILRPFRYEDHWDFYSMVNDTKNLYYV
                     FPEQKTKAASDYLLVHSFIKFPLGQWAIEDKATHQVIGSIRIEHYDAKTRCADIGYFL
                     NYAFWGQGIMTEVVIKLVYLSFHEFGLKTLRIITHLENKASQKVAKKAGFQLKTCFKG
                     SDRNTHKICIYKMYQLTNDR"
     gene            15422..16705
                     /locus_tag="VB649_001469"
     CDS             15422..16705
                     /locus_tag="VB649_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEP1670414.1"
                     /translation="MSKHQDILDYLEKLAIGKKVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYSEIARISDSEVLAGHAGLGHEFSRFSIGA
                     MTQQNIRRYLVKGGLLIVGDRETIQLLALENHNAILVTGGFPVSKRVIEMANSQRIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVEQVMIPITDYGYLCEDSSVEEFNTLIKK
                     TRQVRFPVLDYKRKVIGVVSMRDVVDQLPTTKLTKVMSKNPITARPNTSLANISQKMI
                     FEDLNMLPVTDEENNLLGMITRRQAMENLPNHQPNNPYTYSEQILSNLEETVDYYQVV
                     VEPTMIDSAGNMSNGVISEFLKEISIRALTKKHQKNIIIEQMMVYFLHAIQIEDELKI
                     YPKIITENRRSSTIDIEIFVDDQVIAKAIITTKIN"
     gene            16721..17581
                     /locus_tag="VB649_001470"
     CDS             16721..17581
                     /locus_tag="VB649_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEP1670415.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRDIIKPGVDMWEVEAYV
                     RRRCKEDNVLPLQIGVDGHMMDYPYATCCGLNDEVAHAFPRHYILKEGDLLKVDMVLS
                     EPLDKSIVDVAALDFDNVPEMKKWTGSYTGGLADSCWAYAVGTPSDEIKQLMDVTKEA
                     MYRGIEKAVIGNRIGDIGAAVQEYAESFGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEIDTDIKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            17583..18548
                     /locus_tag="VB649_001471"
     CDS             17583..18548
                     /locus_tag="VB649_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEP1670416.1"
                     /translation="MAEKKWFDKVLSKWQYEPIQVFMRHLQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDIADLLRLMKQNLPKDIFRPTSAIVENIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAINKAYGASQHRDFFIGHLVGLLTSLIILFLLAFALIFSTF
                     SKAAIQVLDKHYHLSDNITTIFLLLIQPITVLIIFVGLMLLYFLLPNVKIKKIRYILP
                     GTLFTSFVMTFLSNLVGNYVVYNVERMVDIKMFGSVMIFIIMLWFIFLARILILGAIF
                     NATYQEMSLGKLEGRSGDMIAILKKTLGNDSDLSPSQSIEDSHTD"
     gene            18659..19942
                     /gene="aroA"
                     /locus_tag="VB649_001472"
     CDS             18659..19942
                     /gene="aroA"
                     /locus_tag="VB649_001472"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEP1670417.1"
                     /translation="MKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGKTRVKGLLK
                     GEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLTAPCQTLNMGNSGTSMRLIAGLL
                     AGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITY
                     TLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVG
                     PQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQI
                     VYEDMNKKEQVTSIRVVYSHLKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQ
                     ELRVKETDRIQVVTDTLNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAI
                     AALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD"
     gene            19935..20426
                     /locus_tag="VB649_001473"
     CDS             19935..20426
                     /locus_tag="VB649_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEP1670418.1"
                     /translation="MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFE
                     QHGEIAFRTIESQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFE
                     TLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANII
                     EDY"
     gene            20634..22085
                     /locus_tag="VB649_001474"
     CDS             20634..22085
                     /locus_tag="VB649_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEP1670419.1"
                     /translation="MTKYPMGGLSHHEELRYFYLLRNLSYLSENEKKEFAFLKSKLEI
                     GRAYAPSKQHYRKSKRQEPYFEDDYYNDYSPNDLLEDDDVNHDSSFVPYGLPIYPKED
                     RYLNKKTKLTARRPIDAPQPIDEDDAFLTESVARCALPRSQKRKHKKKGCMKWFFNIL
                     GLLLMTVLMGLGLMFAKGVFDISTNKANYKPAVSQAFDGQETQDGTNILVLGSDQRVT
                     QGSTDARTDTIMVVNVGNHAKKIKMVSFMRDTLINIPGYSYNDNSYDLKLNSAFNLGE
                     QEDHHGAEYVRRALKHNFDIDIKYYVMVDFETFAEAIDTLFPNGVKIDAKFATVGGVA
                     VDSVEVPDDLRMKNGVVPNQTIEVGEQRMDGRTLLNYARFRKDDEGDFGRTVRQQQVM
                     SAVMSQIKDPTKLFTGSAAIGKIYALTSTNVSFPFVVKNGVSVLGSGKNGVEHVTIPE
                     NGDWVDEYDMYGGQALYIDFDKYQKTLAKLGLR"
     gene            22167..23798
                     /gene="rlmD"
                     /locus_tag="VB649_001475"
     CDS             22167..23798
                     /gene="rlmD"
                     /locus_tag="VB649_001475"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEP1670420.1"
                     /translation="MLKKNDIIQVAISDLSHEGAGVAKHDGLVFFVDNALPEEVIDMR
                     VLKVNKNSGFGKVEAYHYLSSARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDS
                     LYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYY
                     IQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPK
                     VFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTITDSMLGNNYAI
                     SAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEV
                     IEAAVRDAQQNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFI
                     QASVAMGPQKITYVSCNPATMARDIKRYQELGYKLTKVQPVDLFPQTHHVETVALLSK
                     LDVDKHINVEIELDELDLTSAESKATYEQIKEYVLKKFGFKVSTLYIAQIKKKCGIEL
                     RENYNKSKKEKKVIPQCIPEKEDAIMDALRHFKMI"
     gene            23817..24097
                     /locus_tag="VB649_001476"
                     /pseudo
     CDS             23817..24097
                     /locus_tag="VB649_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24134..24652
                     /locus_tag="VB649_001477"
     CDS             24134..24652
                     /locus_tag="VB649_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEP1670421.1"
                     /translation="MRTYENKEQLKAEIDKTFEKYISEFDIIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDGRKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINFIYIMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIYVNTVAPFGTF
                     RTKIRKWKKIVL"
BASE COUNT         7761 a         4299 c         5371 g         7234 t
ORIGIN      
        1 tgacaaatca tcagatgaat agtaagataa acatgtaaaa aataaaaacg ctttcaacta
       61 aagtgttagg atataagggg ggtctctaat ggagaaaacg attgatcaaa gggttgagga
      121 agttacctat aaccgagcta aagtttggca acttgtattg tttgcgttaa acaatacatc
      181 taccaacatt tacctatttg ctttcatgtt tatcacctat ttttcaacag gtgttcttgg
      241 gctagcagct atctttgtta gccaaatcat gggttatatt cgtatctttg atggttttat
      301 tgacccagct atcggtatca tgattgataa aacagatact aagtttggaa aataccgccc
      361 aattttaatt gctggtaata ttattacggc tctatcgctt attctattac ttgctttaaa
      421 taatgttagc gaagggatgc gcttcccact ctttattttg gtattgattg ttcacaaaat
      481 tggttattct atgcaacaaa ccatcacaaa agcaggtcaa actgccttga cgaatgatcc
      541 aaaacaacgt ccaattttca acattgtgga tgccgtcatg ttaacaacct tgatgactgg
      601 tggacagttt gtggtttcag gattcttggt tcctaaattt ggcaacttca cgttggaatt
      661 cttcaatgtg cttatctatg gaacaatcgt tatttcagct attttaggat tattggctgt
      721 tatcggtatc tggtctaaag acaacaaaga atacttcggt cttggtgaaa atacgcaaaa
      781 aacagaatta aaagactaca tgaaagtcat taaaggcaac aaacctcttc aagtcttgtc
      841 aattgcagca gcactcgtta agtttagcgt gcaattcttt ggagactcag ttgtcatggt
      901 tatgctttac ggtatcgtgt ttggtaacta tgccttgtca ggtcaattct cactactttt
      961 tgtgattcca ggtgttttga ttaacatttt gatttcaagt gttgctcgta aaaaaggtct
     1021 tcgtttctca tatgtggcgt cacttcaatt tggtttgatc gccttggctg cttttggggt
     1081 tgtcctttat tttggtaaag ttggtgattt gagtttaagc aacattaacc tttacactat
     1141 ctgctttatc attacttaca tgttggctcg ttacattact caagcgccag ctggtttggt
     1201 tttaacaatg ggggcagata tttcagacta tgaaacatct gaatcaggtc gttatgtgtc
     1261 agggatgatt ggaacaatct tctcattgac agactctatc gcttcttcat ttgcaccgat
     1321 ggttgttgga gctgttcttg caacaattgg ttttgccaaa gctttcccaa caatggaaac
     1381 acctttaaca ccagaactta aaatggcaac cattattctt ttagttggta ttccgtttgt
     1441 cgccttgtca gtcgccttgt tcttgatgag attctacaaa ctggataaag aagaaatggt
     1501 tcgtatccaa gagaaaattc aagtcatgaa agctgcaagt tcaaaagaac gcgtgaagga
     1561 tatcgctcgc aatgtgccat tgtcagatat ggactacgtt gatgtaacga aatatccagt
     1621 tgataaagat tagtcgtttg gaaggagttg ggcaagatgt gctcaactct tttaacttag
     1681 agaaaaagtg atttttagtc atcaaaggac tctttgccta ggtttttaaa atgtcactac
     1741 aatcaggtat aatatcctta tcatcattaa tagaggagat tttgagtgaa aacagttgtt
     1801 tctttaggcg aaattttgtt acgattatca cctccgcagt accagaccct aactcaggca
     1861 accagtctgg aatgtcaatt tggtgggtcg gaattaaatg ttttgtcaac gttggcgcag
     1921 ttagggcata aggtctctct catctcagca ataccagcca atgatttggg acgaatgaca
     1981 aagacctttc ttttttctcg tcaaatcagt caagattata ttattgaaaa aggtcaacgt
     2041 ttagggattt attactatca aaaagggttt tccttacggg ctagtcgcgt gacctatgac
     2101 cgaaaatatt ctgctttttg ggaatcggag ttagccgatt atgagttagc agatgttttt
     2161 gcgggggctg attggtttca tgtgtctggt attaccccgg ctttgaccga taagctttat
     2221 cacttgaccc attatctgat gacaaaggca aaaacagaag gattaaaggt ttcctttgat
     2281 ttaaacttta gggccagcct ttgggactct tttcaagagg ctagagaatt attgtcccct
     2341 ttagttgctt tggcagatgt ttgtattgga attgaaccct tggttttagc aggcgatggg
     2401 gaaaaagatt tgaaagacca attgggattg agtcgaccgt atgaagatca agcgctattg
     2461 gaaaatgttc tttctaagtt ggcaaaaact tacggtgtga ctagctttgc ttttacccaa
     2521 agggaaatgg ggcataccaa tgaatacctc ctgaagggtt atttatatca agatggtaat
     2581 ctttaccaga cagacaagtc tggcattcag gtgctggacc gtgttggtac tggagatgct
     2641 ttcactgctg gcttgattca tggtatgtta caaaaggaag cgcctgacaa ggccttagcc
     2701 attgcaatgg cgagttttaa attcaaacac acgattgagg gtgacagcaa tattattacc
     2761 ccagcagata ttgattattt aataactgat gcatcgcatg agattaaacg ttaacaatga
     2821 gaaaaaagga gaaaaagatg ctatacccaa ctttaaccaa aacaagaagt ttatatgacc
     2881 ttagtggttt gtggcaattc aaattaggag accataaccc agaagattgt ttgtcaacag
     2941 aagacgttat ggttgtgccg acttctttta atgatgtggt ggtcgatacg gataaacgca
     3001 attatatcgg tgatttttgg tatgagcgtt tggttgatct tccaaagtta gctaaagatg
     3061 atgaattgat cttacgtttt ggctcagtga ctcacaatgc tatcgtgtat gttaatgggc
     3121 gtgagctggc ttctcataag ggaggattta ctccttttga agtcgtggta ccagaagatc
     3181 tttaccagga ccatcagatt agaatttctg tccgtgccaa taatatttta gattacagta
     3241 cacttcctgt gggtaattat agcgaagaac gtcaagaaga tggcagcatg aaaaaagtgg
     3301 tcaaagaaaa cttcgatttc tttaattatg cgggtattca tcgtccagtc aaattagtgg
     3361 cgcgtcctaa aacccacatt tcagatatca ccattaccag tgatttatca gatgatttga
     3421 aaacagcaga cctttccatt gctgttgaaa cctcagcggc tgttgatgcg attcaggtga
     3481 ctatccttga tgaggagcgt caagtcgttg gtcaaacgaa cgacggccat gtcaaacttg
     3541 attgcgtgca tctctgggaa gtcctggatg cttaccttta cacagctcgt attgaaatta
     3601 gtgtagatgg taaaattgtt gatacttatg aagaaccttt cggagtgcgt agtgtacatg
     3661 tagcggatgg tcagttcttt gtcaatcata aacctgttta ctttaaaggt tttggcaaac
     3721 acgaagatac ctttatcaat ggtcgtggcc tcaatgaggc ggctaacttg atggatatga
     3781 acttgttgaa agagattggc gctaattcgt tccgtacctc acattaccct tactctgaag
     3841 aaatgatgcg ccttgcagac cgtatgggga ttttggtgat tgacgaaatc ccagcggttg
     3901 gtttattcca aaatttcacg gcttcccttg acttaacacc taaagatatg ggaacttggt
     3961 ctgtgatgga aacaaaagaa gcccacgaac aggctatcca agaattggtg aaacgcgata
     4021 aaaatcaccc atctgttgtc atgtgggtag tggccaatga acctgcaagc catgaagcgg
     4081 gagcgcatga ctattttgaa cctctggtgg ctctttacaa agaattggac cctcaaaaac
     4141 gcccagtgac attggtcaat atttttatgg caacaccaga ccgagatgaa gttatggatt
     4201 tggtggatgt gatttgtttg aaccgttatt acgcttggta tgtggatcac ggtgatctgg
     4261 ctaagggaga agctggccta cgcaaggaat tgttagaatg gcagagcaag ttcccagaca
     4321 aacccatttt gatgaccgag tatggggcag ataccttgcc tggcttgcat tcgatgtggg
     4381 atattccgta tacggaagaa ttccaatgtg atttttatgc gatgacgcat ggagtttttg
     4441 atgagattcc taaccttgtt ggtgaacaag tttggaactt tgcagacttt gagaccaatt
     4501 taatgatttt ccgtgtgcaa ggtaaccata aaggactctt ctcgcggaac cgtcagccta
     4561 aacaagtggt cagagaattt aaaaaacgtt ggacagctat tcctaactac aattacaaga
     4621 aaaaatagtg taaaatagga gatagtagaa acaggaagag gacgatacga tggctagacc
     4681 attagttgaa aagacagcag aacgtttatt acagcttatt ttagaacgtg gatatgacgt
     4741 aggggctaag ctccctaatg agtacgaatt agctcaagac ttggatgtag gacgtagcac
     4801 tatccgagag gctgtcagaa gtttagcaac ccgcaatgtc ttagaagtga gacagggttc
     4861 tggaacctat gtgagttcta aaaaaggggt atcagaagac ccgcttggtt tttcattggt
     4921 gaaagatacg gcaaaattga cagcagattt gtttgaatta cggttgttat tagaacctcg
     4981 gattgctgcc ttagctgctc agaacgcaac accgaaagag attaaagagc ttgaaaagat
     5041 tgtcgtagag attgaagaag ctgtaacagc aggtgatcct aagcacttac agttagatgt
     5101 gaccttccat tcgatgatgg ccaaatttag tggtaatatt gcgatggaca gtttattgcc
     5161 tgtcattaac aagtcaattc atctgataaa tgctaactac acaaatcgtc agatgaaaga
     5221 agattcttta caagcccatc gcgacatttt gacagctatt aaggagagaa accctatcgc
     5281 agcgcatgat gctatgcttt tacatattat gaccgtaaaa cgaacggctt tcttgcctta
     5341 ataaaatatc ggcgaagaac aaacagcaat tgtgagaatt gctgtttttt tagacttttt
     5401 cttgacaagt catcagacga tttgtataat aataacaaga taacggtttc atagaggagg
     5461 aaaaatggat gttaacccaa ttaaaagaga attacttttt cgctgttgtg cgtggaaaaa
     5521 ccgcagaaga tgcgattgaa atcgctaaat atgcggtttt aggtggaatt cgtaatattg
     5581 aaattactta ctccactcca aatgcttctg aggtcattag caaattatca gatgacttta
     5641 aagatgacac aagtgttgtt attggagctg gtacggtaat gactactgaa ctcgcaaaag
     5701 aagcgattgc agcaggtgcc aaattcttag taagcccgca tttttccaaa gaaatcgctg
     5761 acattgctaa ccaagaaggc aatctttact tcccaggttg cgccacagca actgaaattg
     5821 tgactgccat gaatgcttct tgtcctatta ttaaggtttt cccaggaggg gttgttggcc
     5881 caagttttat caaagatatt cacggtccaa tccctgaggt tgatttgatg ccttctggag
     5941 gggtttcagt tgataacgtg aaagagtgga aaaatgctgg agcagtcgct gtaggtgttg
     6001 gttccgccct tgctagtaag gtggcgacag agggttatga cagtgtcact cggattgcgc
     6061 aatcatttgt atcagccctt gactaagtgt ggaagttatc acagaggaga cgaacatgac
     6121 atttaacgat gcgaacttta tgttaaaaaa tgaagctgct aaaaaactgt atcaacagat
     6181 tcaagatcaa ccgatttttg actatcactg tcacttagat ccaaaagaaa tttttgaaga
     6241 taaggtctat gacaatattg ttgacttatg gttaggtggg gatcactaca agtggcgatt
     6301 gatgcgtgct aatggcatct cagaagaaga aattactggt tcagcgtcta aacttgataa
     6361 atttaaagct tttgcaagaa ccttagaacg ttcctacggt aaccctgttt atcattggtc
     6421 agctatggag ttgaaaaatg tttttggcgt ggaagagctg ttgacacagg acaatgcgga
     6481 agagatttac catcgtttga atgcttatct ggttgaccat aagattagcc cgcgcaaatt
     6541 aatcgcagac agcaaggtga cttttattgg aactactgat caccctcttg atgacctcga
     6601 atggcatcaa caacttgcgg acgatagcac tttcgagaca gttgtagcac caacctttag
     6661 accagatgag gcttttgtag agcaccgcaa ttttgcacag tttgtggtgc gtttaggaac
     6721 ttcaactggc agccgcatta cagactttac gacgtttatg gcagccatgg agaaacgcat
     6781 tgcttacttt gctgaaaaag gctgcaaggc aagtgatatc agctttgcag aaattgtttt
     6841 tgaaaaggct acaccagaag ctttaaatca gattatggcc caggtgctag cgggtgatac
     6901 accaagccag cttgacatca accaatggca gactgctgtt tttgcagacc tttgtcgatt
     6961 gtacaagcaa tatggttttg taacccaagt tcattttggt gctctgcgca acaaccattc
     7021 tgatattttc aaacgtttag gagcagatgt aggggtggat tctctaggag accaaacagc
     7081 cttaaccagc aatatgaacc gtttattgga taacttggtg cagactgata gcttaccaaa
     7141 aatgatctgg tataacttaa acccaagtta caacattgca gtagccaaca ctttggctaa
     7201 tttccaagct aatgaagccg gtgtggcaag ttaccttcaa tttggagcag gttggtggtt
     7261 tgcagatacc aaacttggaa tgattagcca gatgaatgct cttgctgaac aaggaatgct
     7321 tgctaatttt gtaggcatgt taacggattc tcgttccttc ttgtcttatc aacgccatga
     7381 ttacttcaga cgtattctgt caacttatct tggagaatgg attgaagaag gggaagtccc
     7441 agaagattat caagccattg gtcagatgac taaagacatc gcttacgaca acgctgttcg
     7501 ctattttaat taaaactgta tcaatagaga agcgcagcct tctcaataaa tgaaaatcgt
     7561 gtggaaatga aaggaaaaag gagcctatca gctctaggta attgtatatg aaaatgtcat
     7621 ttcgctggta tggtaaacag gacccagtca gcttagaaga aatcaaagcc atcccaggca
     7681 tgcagggaat tgttacggcg atttacgatg ttccggttgg tcaagcttgg ccacatgaga
     7741 acattcttgc cttgaagaaa atggtcgaag atgctggttt agagatttca gttattgaat
     7801 ctatcccagt tcatgaagac atcaaacaag gcaagccaac gcgtgatgca ttgattgaaa
     7861 actataaaac ctctattatc aacgttggta aagcaggtat tccggtggtt tgttacaatt
     7921 ttatgccagt ttttgactgg acacgttcag atcttaacca tccactaccg gacggatcca
     7981 catcgcttgc tttcttaaaa gctgatttag agggtgttga tccagtagct gacgacttga
     8041 atctaccagg ttgggattct tcttattcta aggaagaaat gaaagccatc atcgagaatt
     8101 accgcaacaa tatctctgaa gaagatttat gggcaaatct agactacttc atcaaagcta
     8161 ttatgccaac cgcagaagca gctggtgtga aaatggcgat ccaccctgat gacccaccat
     8221 atggtatctt tggtttgcca cgtattataa caggtcaaga tgcagttgag cgcttcttga
     8281 atctctatga ttctccaaac aatgggatta ccatgtgtgt agggtcgtat gcttctgatc
     8341 ctaaaaatga tgtgattgcc atgactgagt acgctcttaa acgtaaccgt atcaacttta
     8401 tgcacacgcg gaacgtgaca gtcggcgctt ggggcttcca agaaacagct cacctatcac
     8461 aagctggtga tattgatatg aatgctgttg tcaaattatt ggttgactat gattggaaag
     8521 gggctcttcg tccagaccat ggtcgtcgta tctggggaga tcaaaccaaa acacctggtt
     8581 atggcttgta tgaccgtgct ttgggagcta cttactttaa tggtctttat gaggctaata
     8641 tgcgtgctgc tggtaagaca ccagactttg gcattactgt caaaacagtt ggtgacaaat
     8701 aagaaagagg aataatatga ctagagtaat tgattttaaa gataaggttg tgattgtaac
     8761 aggtgctggt ggcgtgcttt gcggctacat ggccaaagag tttgctaaag caggtgccaa
     8821 ggtagctctt ttagatttga accaagaagc agcacaagct tttgtaactg agattgaagc
     8881 agaaggtggt gtggctaaag cttacaaagc aaatgtcctc tcaaaagaga atttagaaga
     8941 ggtacgtcag gctgttttag ctgattttgg tccagcagac attctggtca atggagctgg
     9001 tggaaacagt ccaaaagcga ctactgataa tgaatttcat gaggttggtt tgcctgaaga
     9061 gaccaaaact ttctttgatt tagatgaagc gggaattagt tttgtcttta acttgaacta
     9121 cctaggaaca ttgcttccta cgcaagtttt cgctcaagac atggttgggc gaaaaggggc
     9181 taacatcatt aacatttcat caatgaatgc tttcacacca ttgacaaaaa tcccagctta
     9241 ttcaggagct aaggcagcta tttccaactt tacgcaatgg ttagctgttc acttctcaaa
     9301 agtgggaatc cgttgtaatg ctatcgcccc aggcttcttg gtgactaacc aaaatcgagg
     9361 tcttttgttc actgaagagg ggcaaccaac agcacgtgct gaaaaaatcc ttaacaatac
     9421 gccaatggga cgtttcggag aagcagaaga attgattggt ggtctcttct tcctagctga
     9481 tgaacaatca gcaagcttcg ttaacggcgt tgttctccca attgatggag gctttgcagc
     9541 ttactctggc gtttaatcct tagtaactaa ctcactcaag aaaacgtgat gccttgggtg
     9601 agtttttgtt tagaggttag ttgctattat cataagtgat atgatgactt tgctaacttt
     9661 agaatgatcg ttaagagaga ataatttggc aaaaatttat aaattcatct taaaataaag
     9721 gatattaaga aaaatgaacc taatgttagt tttctaattg acagcgtttt ctagctatgt
     9781 tacaattaag tcatcagatg aattataatt gattggagga aaacatgacg actaaaaagg
     9841 aagcctttgt cttctgcgta gactcagatg gctgtgcgat ggatacgatg acctataagc
     9901 atcagctatt ctttggtcca attgctgcag aggtctttgg ggtgacaaat agagaagtat
     9961 ttttaaaaga atgggaccat gttaatctgt actcacgcac gcgtggggtt aatcgttttg
    10021 ttgggcttgt catgggactt gactatgcag gattgaaagg cattgaccgt ttgaaagatt
    10081 gggttgccaa caccaaatcc ctctccaatg cttcactgga agcagagctt gctaaagaag
    10141 ctagtgatga ccttcaaaaa gctttggaat ggtctaatga agtgaaccgt caaatcaaag
    10201 cttatgaagg tgaggctttg gcttttccag gagctgaatc aggccttgag aaattgcatc
    10261 agctagggaa agtattcgtt gtgagttcag ccaataaaga agctgtcgaa gaagagtggc
    10321 acgatcaagg attaatggca catgttgatg acttgtattg ccaagactgt ggtaaaaaag
    10381 aggatgttat tgcagagctt cttcaaaaag ggtatcaaaa agaacgcctc atgatggttg
    10441 gcgattctcc aggagatttg gccgcagcag agcaaaatca agtggctttc ttccctatat
    10501 tagtcggcaa agaggcgcaa tcttgggctg acttaaaaga agctgtggca gatgcctttg
    10561 tgacaggaga actgtctgac ctagatttta atagtttgaa agaaaccttc tggcataact
    10621 tagattagat caatagcaga gctactaatt agattgacta gtccaaaagg atgagaaaag
    10681 aagtaagtag agggatttgg taagaaggta ttaaaaaacc gagaccctct tgaaaggaaa
    10741 agaaatgaca catttagtag atttacgcaa aaaaccttat caccttgatg accaagccat
    10801 cgcttgggta gaagaaacca ttgcctccat gtccttggag gagaaaattg ggcagttatt
    10861 tgttaacatg ggagctagtc gtaccgaaga gtatttgacc caagtgctta atgattataa
    10921 aattgcggcg gttcgctaca ataaaggcat ggccgacgaa gtttgggaac aaaactacat
    10981 tttacaaacc aaatcaaaaa ttccactctt aattgctgct aacaccgaag cgggtggcga
    11041 tggcgcagtt aatgatggca caaaggttgg ggacgagatt aaggttgccg caacaaatga
    11101 tccaaagtat gcttacgaaa tgggccgcat tgcagggatt gaagcagcag cagttggctg
    11161 taacgcttcc tttgctccta ttgttgacct gacacgcaac tggtgcaacc caattattgc
    11221 tagccgtaac tggggctcaa acgtggacca aatcattacc ttttctaaag agtacatgag
    11281 agggattatg gagcatggca ttatgccatt tgccaaacat ttcccagggg acgggattga
    11341 tgaacgtgac catcacctct cttttgcatc aaacccaatg acaaaagacg agtggatgtc
    11401 taccttcggt cgtatctatg gagaactgac agaagctggt cttccaggta ttatggcggg
    11461 tcatatccac ttgccaaatg tggagaaaga aatgcatcct gagcgtgaat tggatgacat
    11521 gctaccagct tcactcaaca aaacgttgtt ggatgaattg ctgcgcgggg agcttggtta
    11581 caatggggct attgtcacag atgcttctca catggttgcc atgacagctt ctatgccacg
    11641 tcgtttgatg ctaccaacgg ccgtggaagc gggatgtgac ctcttcttat tctttaatga
    11701 tccagatgaa gacttgcaat ggatgaaaga aggctatgag gctggtattt tgacagaaga
    11761 acgactccat gatgcccttc gccgtacgct tggcttgaaa gcacgtctag gacttcattt
    11821 atatgaaggt cgtcgtgaag agattatgct accaaaagaa gaagcgatga cactgattaa
    11881 taccaaagaa gctcaagcca ttgctgacga ggtagctgac aaagccatta ctcttgttaa
    11941 agataagcaa aaggatattt tcccagtcac gcctgaacgc tacaaacgca ttttgattgt
    12001 caatgtagaa ggttacaaag gtggttttgg tgcgatgatt gcagggcaga aaaaacgagc
    12061 atccgatgtg gtcaaagaat tgctagaagc gcgtggccat gacgtcacag tgtgggagtc
    12121 aacggaagaa cgtatcatgc aattgccaga aagtgaacgt gccgcagcca ttgccaatat
    12181 ttatgcccaa aaacaaccga tttccaattt gacagaccat tacgatttaa tccttaacct
    12241 tgttgatgtc aactctggtg gaacagttca gcgtattgtc tggccagcag ctaagggtac
    12301 accggatcag ccattttatg tgcatgaaat cccaacaatt gtggtatcag ttcagcatgc
    12361 ctttgcccta gcagacatgc cacaagtagg gacttatatc aatgcttacg acggtaagga
    12421 caataccatg aaagctttgg tggagaaatt ggctagcgaa tccaacttca ccggtgtttc
    12481 accagtagat gctttctgtg gccttattga cacgcattta tggagagaat attaggaaag
    12541 tcattgtttg agtaagtgag agtagtaaag gacgtaaggc atgccaaaaa cagttgactt
    12601 aaggcaaaaa acctatcagc ttgacgatca gcaagttgct ttggtagaag ataccttagc
    12661 aggattaagt gatgaagaga aaattggaca actttttgta aatctttttt tctttggtga
    12721 agatgcgttt agaagcaatc aattaagcaa caaagatatc ttggcaaact atcatatcgg
    12781 tggcgctcgt taaatgaacg gcacccctga acagatgcaa ggacttctaa atgagttgca
    12841 gagccacagc aagattccct tgctagtcgc agccaattgt gactctggtg gagatagtgc
    12901 ggtaaaaggt gggacctaca ttgcttcacg agctcaatcc gaggctagcc atgacccttg
    12961 gcttgtttac tatgcagggc ttgtttctgc tagggaagaa acaagctcta ggcgtcaata
    13021 ttaactttga tggcagtctt cttaaatctc ctgaagacct tgctatcact ggctgtgaag
    13081 agcattagtt tggcaaaaag aagctgcaca aaaaaccatt atccttttaa aagatactca
    13141 agaaaacctc ccgattagcc cagaaactca cagacgtatt cgcctctatt gcttagaggg
    13201 gggaaaggag gaattatgag tgccaatgat caagtggtcg gaaaccttaa acaggcccta
    13261 gaggcaagag gttacgaggt gacgattaat gatggcacga gtcgcgtcaa gggagagatc
    13321 ttggcctatc gtaatgacgt ggatttggcc ttgacggtgg tcaatgttgt tgactatgaa
    13381 gctcaaaata attaccgtat ccaatgggag acagccatgt ttaatgaggt gccttggtac
    13441 gtttatgaag ttccaactgt ctttatttcc cttaattaca agacgcatct gcacgatgcc
    13501 actatggtca aaacagcgat taatgcttat caccataata ctaatacgat tgcagccctt
    13561 ttggattgtc tagaaggcaa agcagctttt aaaggccaac ctaatgagtt agtttgggcc
    13621 aataagtggc aagccaagct gtaataaaga tgatgatgga aaagttagaa ggatcttcta
    13681 actttttttg tttctcaaaa acgaaaaccc ctgactataa aatgagttaa taaaactata
    13741 aaatgaaaat ataatctttt tgaaattaat aagtcgctcg cttataaaat aattatctaa
    13801 aaaattaaat taaggtagct atatactaat gatattattg taataataat ttgattaact
    13861 aatagtaaaa gttaactgtt taactttaat cgtctgctgc gtttgtagtg gggacagcag
    13921 tagcatacac agaagaaatc cctactactc caatactcac tttagaggtg actgagcgaa
    13981 gagaagcgat taataaaatt aacagattaa gtgatcagta tcctaacgac cctgagattc
    14041 aggcaacttt agaagatacg actaataaaa ttttagcatt tgaatcagct gatattactg
    14101 aagcacttat tgctgaagta aattctgaag ttactcgatt gaatgaagaa aaaatagcac
    14161 gtgatgcagt agatacagct gaaaaagcag atgcagaaaa acgtcacgac ttcttgaaac
    14221 aacaagacgc tgttgttatt gctattcaag aattggcaaa tattcctgct gaaaaagcct
    14281 tcagacaata tgctaatgat aatggtgttg acgatgtttg atcttacgac gacgctacta
    14341 agacgtttac agtaacagaa atagttactg aaattcctgg agatgctcta gttgaaccag
    14401 aaaaactaaa agcagaaatt ccttttgttc cattaacacc agcaactcca atcgctttag
    14461 atattaggaa aactaaagat acaaaacctg tagttaaaaa agaagaaaga caaaacgtta
    14521 atacccttcc tacaactggt gaagagtcta acccattctt tacagctgct gcgcttgcaa
    14581 taatggtaag tacaggtgcg ttagttgtaa gttcaaagtg caaagaaaat tagttgctat
    14641 ttgttctagc aaatgaaaca agggaatcga aagattctct ttttctgata tttaaaaatg
    14701 ctacagttta taatagcttg aaagactaaa tgttctcaaa ctcattagaa caagctttaa
    14761 taaaactaac ccagttgtat caaaggatag ataaagacta agactgttat agaatatttg
    14821 caaaagattt gttataatgg acccaataca ggtattgtga aaggtataat atggatattt
    14881 ggacaaagct tgcagtgttt gctttttttg agactccgaa agtaatatta cggccttttc
    14941 gctatgaaga tcattgggat ttttacagca tggttaacga cactaaaaac ctttattatg
    15001 tttttccaga acaaaaaact aaggcagcaa gtgactatct tttagtacat agttttataa
    15061 agtttccttt aggtcagtgg gcaatagaag ataaagcaac ccaccaagta ataggttcta
    15121 ttagaattga gcattatgat gctaaaacgc gttgtgctga tattggctat tttttaaact
    15181 atgccttttg gggacaagga attatgacag aagtcgtaat aaaacttgtt tatttatctt
    15241 ttcacgaatt tggtctcaaa acgttgcgta ttataactca tttagaaaat aaggccagcc
    15301 agaaagtagc taaaaaagca ggttttcaac taaaaacctg ttttaaagga agtgatcgta
    15361 atactcataa aatctgcatt tataaaatgt accaactaac taatgatagg tgataatcat
    15421 tatgagcaaa catcaagata ttttagatta tttagaaaaa cttgctattg gtaaaaaagt
    15481 gagtgttaga agcatttcaa accacttaaa agtaagcgat ggaacagcct accgtgctat
    15541 taaagaggca gaaaatcgag gtattgtcga aaccaaacca agaagtggaa ctgttcgtat
    15601 tgaaaaaaaa ggacgggttc gtattgaccg tctgacctat tccgaaattg ctcggatcag
    15661 tgattcggaa gtgctagcgg gacatgctgg tttaggacat gaattcagta ggttttcaat
    15721 tggtgctatg actcaacaaa atattcgtcg ttacttggtc aaaggagggt tattaatagt
    15781 tggggatcgt gaaacgattc aactcttagc tcttgaaaac cataatgcca ttttggtgac
    15841 gggcggattt ccagtatcca aacgtgttat tgaaatggca aatagccaac gaatcccagt
    15901 tatggtaact cattatgata cctttactgt ggcaacaatg attaatcacg cgctatctaa
    15961 tattcgtatt aaaacagatc tcaaaacagt tgaacaggta atgataccta ttacagatta
    16021 tggttacctt tgcgaagaca gctctgttga agaattcaat acattaataa aaaaaacacg
    16081 acaagtcagg tttcctgtat tagattataa aagaaaagtg attggtgtag ttagtatgcg
    16141 tgatgtggtg gatcagttgc caacaactaa gcttaccaag gtcatgtcta aaaatccaat
    16201 aacggctaga ccaaatacta gtcttgctaa tattagccag aaaatgatct ttgaagattt
    16261 aaacatgtta cctgtcactg acgaagaaaa caatttactt ggtatgatta ctcgtagaca
    16321 agcaatggaa aatttgccaa atcaccaacc aaataacccc tatacttata gtgagcaaat
    16381 actttctaac cttgaagaaa cggttgatta ttaccaagta gtagttgagc caacaatgat
    16441 tgatagtgct ggtaacatgt caaacggtgt tatttcagag ttcttaaagg aaattagtat
    16501 cagagccctc acgaaaaagc accaaaaaaa tatcattatc gaacaaatga tggtatactt
    16561 tttacatgct attcaaattg aggatgaatt aaaaatatat cctaaaatca ttactgaaaa
    16621 tagacgaagc agcaccattg atattgaaat ttttgtggat gatcaagtga ttgctaaagc
    16681 tattattaca acgaaaataa attagaggag taacaaaaca atgataacat taaaatcagc
    16741 ccgtgaaata gaagcgatgg atagagcagg agacttctta gcaggtatcc atattggctt
    16801 aagggatatt attaagcctg gtgtggatat gtgggaagtg gaagcatatg ttcgtcgccg
    16861 ttgtaaagaa gacaacgttc ttcctttgca aataggggtt gatggtcaca tgatggacta
    16921 tccttatgcg acctgttgtg gtctaaatga cgaagtagca catgcctttc cccgtcatta
    16981 cattctgaaa gaaggggatt tgcttaaagt tgacatggta ctcagtgagc ctttggataa
    17041 atcaattgtt gatgtagcag ctttagattt tgataacgtg cctgagatga agaaatggac
    17101 aggatcttat actggtggtt tagctgactc ttgttgggct tatgctgttg gaacaccgtc
    17161 tgacgaaata aagcaattaa tggatgtcac caaagaagcc atgtaccgtg gtattgaaaa
    17221 agcagtaatt ggcaatcgta ttggtgatat tggcgcagct gttcaagaat acgctgaaag
    17281 cttcggttat ggtgtcgtgc gtgatcttgt tggtcacggt gttggtccta caatgcatga
    17341 agagccaatg gtaccaaact atggaacagc aggtcgtgga cttcgtctaa aagaaggcat
    17401 ggtcttgact gttgagccaa tgattaatac aggaacttgg gaaattgata ccgacatcaa
    17461 gacaggttgg gctcataaaa ccctagatgg tggtttatct tgccaatacg aacaccaatt
    17521 tgtgattact aaagatggtc ccgttatttt aacaagtcaa ggagaagaaa gaacttacta
    17581 aaatggcaga aaaaaaatgg tttgataagg tactgtccaa gtggcagtat gaacccattc
    17641 aagtctttat gaggcattta caaagtgcag aaatggattt atctgccatt gcggttgcgt
    17701 attaccttat cttaacggcc tttccattaa ttgttattgc agccaatatt tttccttacc
    17761 tcaatattga tattgctgat ttgttacgtt taatgaagca aaatttgcct aaagatattt
    17821 ttagaccgac ttctgcaatt gtagaaaata ttttctctaa accgtctgga agtgttttgg
    17881 gagtagcgac tttgacagga ttgtggacaa tgtctcgaag tttgacatcg ctgcaaaaag
    17941 ctattaataa agcctatggc gcttctcagc atcgagattt ctttatcgga cacttggttg
    18001 gtttgttgac cagtttaatt attttatttt tattagcctt tgccttaatc ttttcaacat
    18061 tttctaaagc tgctattcaa gtgctggata agcattacca tttgagtgat aatattacaa
    18121 cgattttctt actcctcatt caacctatta cagttttaat tatttttgtt ggcttgatgc
    18181 tactatattt tttattaccc aatgttaaga ttaaaaaaat tcgctacatt ttaccaggaa
    18241 ccctatttac atcttttgtg atgacatttt tgagtaatct ggttggcaat tacgttgtgt
    18301 ataatgttga gcggatggta gatattaaaa tgtttggttc agttatgatt tttatcatca
    18361 tgctatggtt tattttctta gcaagaatcc tgattttagg agctatattt aatgcgacct
    18421 atcaagaaat gtccttgggg aaattagaag gtcgtagtgg tgatatgatc gctatcctta
    18481 aaaaaacact tgggaatgat tcagatctat ctccttcaca gtctatcgaa gatagtcaca
    18541 ctgattgata caaaaaagat aataagtcgt ggagtgagaa actattttct tgcttcattt
    18601 tttatgagga tgaatagaaa atcattgatc ttagcaaata gaaaggcaga tgaaacggat
    18661 gaaattgcga acaaatgcag gaccattaca gggaacgatt caagttccag gagacaagtc
    18721 cattagtcac cgggcagtca tattaggagc cgttgctaaa gggaaaacac gagtaaaagg
    18781 actcctaaaa ggagaagatg tgctttccac gattcaagcc tttaggaatt tgggggtccg
    18841 tatcgaagaa aaagatgacc agcttgtgat agaaggtcaa ggttttcaag gattgaccgc
    18901 tccttgtcag acacttaata tgggaaattc tggaacctct atgcgtctca ttgctggatt
    18961 attggcaggt caacctttta gtgtcaaaat gattggcgat gaaagcttat ccaaacgtcc
    19021 tatggatcgg attgtttatc cgttaaagca aatgggggtt gagatatctg gagaaacaga
    19081 taggcaattt cctccactac aattgcaagg taatcgtaat ttacaaccaa tcacatatac
    19141 cttgcctatc tcttctgctc aggttaagtc agctatttta ttagcagctt tgcaagcaaa
    19201 aggaacaaca caggttgttg aaaaagagat tactcgaaac catacagaag aaatgattca
    19261 acaatttggt ggacgattga tagttgatgg taaacgcatt actttggtgg gaccccagca
    19321 gctcactgct caagagataa ctgtccccgg agatatttct agtgcagctt tttggcttgt
    19381 cgccggctta attattcctg gttcggagct ccttttaaag aatgttggag tcaatccgac
    19441 acgaacaggg attcttgaag tggttgaaaa aatgggagca cagattgtct atgaagatat
    19501 gaataagaaa gagcaagtaa ctagtattcg agtggtatat tctcacttga aaggaactat
    19561 catatcagga ggtcttatcc ctcgattgat tgatgaactt cccatcattg cacttcttgc
    19621 aacccaagca caaggaacaa cctgtattaa agatgctcaa gaactacgag tcaaagaaac
    19681 agatcgtatt caagtagtaa ctgatactct taacagtatg ggagctaata tcaaagcgac
    19741 agcagatggc atgattatca aaggccctac ggtactatac ggggctaaca caagtaccta
    19801 cggagatcat cgtattggta tgatgacagc aattgcagcc ttgcttgtta aacaaggaca
    19861 ggtccatttg gataaagaag aagccatcat gacgtcttat ccaacgtttt tcaaagattt
    19921 agaaaggctg tgtcatgact aaagtgttat tgggatttat gggagtgggg aaaacaacgg
    19981 tttcgaaaca cctaagtatg cactgtaaag atatggatgc tattattgaa gctaaaatcg
    20041 gtatgtctat tgcagctttt tttgaacagc atggagaaat agcatttcga acaattgaaa
    20101 gtcaagtgtt aaaagatcta ttgtttgcaa atgataatag tgtcatcgta acaggtggcg
    20161 gtgtagtggt tttacaagaa aatcgacaat tactgagaaa aaatcaccag cataatattt
    20221 tattggtagc ttcttttgaa actttgtacc agcgtttaaa acatgataaa aagtctcaaa
    20281 gacctctatt tcttaagtac tctaaggaag cattttatga attttatcaa caacgtatgg
    20341 tattttatga gggactttca gatttagtaa tcagagttga ccatcgtacg cctgaagaag
    20401 ttgccaacat cattgaggat tattagtagg tcattgtcgt aatctgatat ttatggtttt
    20461 aaacaggtat ctgtctaaag cacttcttat ggcaagttgg ctttattaaa tattaggaaa
    20521 taatcttgat tattctataa tgattaaaat tttgagagga caatctggct aatataggtt
    20581 ataatggtag tattcgttaa aagtgcaatt gtaatactaa gagatgataa gatatgacaa
    20641 aataccccat gggtggcctt agtcaccatg aagaattacg ttatttttat ctcctaagga
    20701 atttgagtta ccttagtgag aatgaaaaaa aagagtttgc ttttttaaaa tctaaattgg
    20761 aaattggtcg agcttatgct ccttctaagc agcattatag gaagtcaaaa cggcaagaac
    20821 cttactttga agatgactac tataacgact actcaccaaa tgatttacta gaagatgatg
    20881 acgtcaacca tgactcttct tttgttccat atggtttacc gatatatcct aaagaagaca
    20941 gatatttaaa caaaaaaaca aaacttacag ctcgtagacc tatagatgct ccgcagccta
    21001 ttgatgaaga cgatgctttt ttaacagagt ctgttgctcg ttgtgctctt cctagatctc
    21061 aaaaaagaaa gcataagaaa aaaggatgta tgaaatggtt ttttaacatt cttggcttat
    21121 tgctaatgac tgtgcttatg gggttagggt tgatgtttgc aaaaggggtt tttgatattt
    21181 ctactaataa agctaattac aaaccagctg tttcccaagc ttttgatggt caagaaactc
    21241 aagatggtac gaacattctg gttttgggtt ctgaccaacg agttactcaa ggttctacag
    21301 atgctcgcac agataccatt atggttgtca atgtcggcaa ccatgctaaa aaaataaaaa
    21361 tggtctcttt tatgcgtgac actttgatta acattccagg atacagttat aatgataatt
    21421 cgtatgatct taaattaaat agtgcattta atcttggaga gcaagaagat caccacggag
    21481 cagagtacgt tcgacgggcc ttaaaacata attttgatat cgacattaag tattatgtga
    21541 tggtagattt tgaaacattt gcagaagcta ttgacacctt gtttccaaat ggtgttaaga
    21601 ttgatgccaa atttgcgaca gtaggtggtg tagctgttga ctccgtagaa gttccagatg
    21661 acctgcgaat gaaaaatggg gttgttccca atcaaaccat cgaagttgga gaacaacgca
    21721 tggatggtag aaccttgctc aactatgctc gtttccgtaa agatgacgaa ggagatttcg
    21781 gacgaaccgt ccggcagcaa caggttatgt cagctgttat gtcccaaatc aaggacccaa
    21841 ctaaactctt tacagggtct gcggctattg gtaaaatcta tgcgctgact tcgaccaatg
    21901 tttcttttcc atttgttgtt aaaaatggtg tttctgtttt aggaagtggg aaaaatggag
    21961 ttgagcacgt gaccattcca gaaaatgggg attgggttga cgaatacgat atgtatggag
    22021 gacaagccct ttacatagat tttgataagt atcagaaaac gttagccaaa ttaggtctgc
    22081 gctaagatat ggtataatgg agagtaacta aagttgctct tcttttttga gcaatggtta
    22141 gccctagaaa aggaaaaaga ataagaatgt tgaaaaaaaa tgatattatc caagttgcta
    22201 tttcagattt aagccatgag ggagcaggtg ttgctaaaca cgatggtttg gttttctttg
    22261 ttgataatgc cttgccagaa gaagtgattg acatgcgtgt cttaaaggtc aataaaaaca
    22321 gcggttttgg caaagtagaa gcctatcatt acctgtcgtc agctagaaat gcagatgtca
    22381 atttaactta tttgcgaaca ggcattgcag accttggaca tctaacttat gaagaccaac
    22441 tgactttcaa aaagaaacaa gttcaggaca gcctctataa aattgctgga atcagtgacg
    22501 tgacagtcga aagcacgatt gggatgacag aacctttagc ttaccgaaat aaggctcaag
    22561 ttcctgttag acgtgttaat ggtcagctag aaacaggctt tttccgcaag cattctcatg
    22621 acttgattcc tatttcggat tattatattc aggacaaaga gattgatcgt ctcattaatt
    22681 ttacccgtga tttattacgc cgctttgata ttaaaccgta tgacgaaaca gaacaaacag
    22741 gtctcttgag aaatattgtt gttcgccgag gccattactc tggagaaatg atgctggtct
    22801 tagtgactac acgcccaaaa gttttccgtg ttgaccaagt cattgaaaaa atcgttgaag
    22861 cttttccagc agtggtgtct attattcaaa atattaatga taagaacacc aatgcaatct
    22921 ttggtaaaga tttcaaaacg ctttacggca aggataccat tactgatagc atgctgggaa
    22981 acaactatgc catttctgct cagtctttct accaagtgaa tacggttatg gcagaaaaac
    23041 tctatcaaac agctatagcc ttttcagacc tttctaaaga tgatattgtg attgatgcct
    23101 actcaggtat cggaaccatt ggcctatcat ttgctaaaac agttaaagct gtttatggtg
    23161 ttgaagtgat tgaagcagct gttagagatg ctcaacagaa tgccgctctt aatggcatca
    23221 ccaatgccta ctttgtcgca gataccgcag aacatgccat ggcaacatgg gcgaaagatg
    23281 gcattaaacc aagtgttatt ctggtagacc cgccacgaaa aggcttaaca gaaagtttca
    23341 tccaagccag cgtggcaatg ggaccacaaa aaatcaccta tgtttcctgc aacccagcca
    23401 ccatggcgcg tgacatcaag cgttatcaag agttgggtta caaactgacc aaagtgcagc
    23461 ccgtagattt gtttccgcaa acgcatcacg tcgagacggt agctcttttg tccaaacttg
    23521 atgtcgataa gcacataaac gttgaaattg agctggatga gcttgatttg acaagtgctg
    23581 aaagtaaggc tacttatgag caaattaaag agtatgtact gaagaaattt ggatttaagg
    23641 tttctacact gtatatcgca caaatcaaaa agaaatgcgg tatagagttg agagagaatt
    23701 ataataagtc aaaaaaagaa aaaaaagtta tcccacaatg cataccggaa aaagaagatg
    23761 ctattatgga tgcattaagg cactttaaaa tgatttaata aagagggagg gtatttatga
    23821 gattgataat aaaaataatc ttgttttcaa tgggactttt attaagtatc ctaactgcct
    23881 tttttacatt catgctcggc ataggaacag gaatactata tttactgatg atattttgta
    23941 tatttggagc catagcatct tttttacaaa aagaagttag cattggtata gaagcattga
    24001 ttattggatt tttagttagt ccttacggaa taccgatggt gggagcagct gttatagctt
    24061 cttagaaggt gtaaatagaa aaataaggtc aatttaaatc aaaacattga tgaatcagaa
    24121 agaaggtgaa tttttgcgaa catacgaaaa taaagaacaa ctaaaagctg aaatagataa
    24181 aacatttgag aagtatattt cagaatttga tattattcca gaaaatttaa aagataagag
    24241 agctgatgaa gttgatagaa ctccagcaga aaaccttgct tatcaggttg gctggaccaa
    24301 cttggttctt aaatgggaag aagatggaag aaaggggctt caagtaaaaa caccatcgga
    24361 taaatttaaa tggaatcaac ttggtgaatt atatcagtgg ttcacggata cctacgctca
    24421 tttatctctg caagagttga aagcaaaatt aaatgagaat attaatttta tttatattat
    24481 gattgattcg ttgagtgagg aagaattatt tgaaccgcat atgagaaagt gggctgatga
    24541 agcgactaaa acagcgactt gggaagtgta taagtttatt tatgtaaata cggttgcacc
    24601 ttttggaact ttcagaacta aaatcagaaa atggaagaag atagtattat aaattatatt
    24661 tttaa
//
LOCUS       DATTYN010000031        24447 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.31, whole genome shotgun sequence.
ACCESSION   DATTYN010000031 DATTYN010000000
VERSION     DATTYN010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24447
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.31"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(16..927)
                     /gene="rgg4"
                     /locus_tag="VB649_001478"
     CDS             complement(16..927)
                     /gene="rgg4"
                     /locus_tag="VB649_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Rgg4/ComR"
                     /protein_id="HEP1670422.1"
                     /translation="MLEHFGGKVKVLRLEKRISREDLCGDESELSVRQLARIELGQSI
                     PSLSKVIFIAKALNVSVGYLTDGADLELPKRYKELKYLILRTPTYMDDGKLQVREEQF
                     DEIFEDYYDKLPEEEKIIIDCLQATLDTLLSENTNFGIDLLQEYFNQIKTKVRFRQND
                     LILLELYLAYLDIEGMDGQYSDKIFYDSLLDNLSEQFEQFELDELFIVNKIIIDISSL
                     SLKNNRLDNLEKAIEMSQKIMAKIQDWNRMPILKLIEWKYFLIKQKDIIKAEQSFMKA
                     CLFAQMTADQYLENKLIQEWEKDVKSY"
     gene            complement(1062..2354)
                     /gene="purB"
                     /locus_tag="VB649_001479"
     CDS             complement(1062..2354)
                     /gene="purB"
                     /locus_tag="VB649_001479"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEP1670423.1"
                     /translation="MIERYSRPEMAAIWTEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIREKADFDIDRILEIEQDTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVADKAREHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEQYVCDKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVSLWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMMRNMESTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPL
                     LEEDIKVTSCLTQEEIDELFNPIYYTKRVDDIFKRLGI"
     gene            complement(2374..3792)
                     /locus_tag="VB649_001480"
     CDS             complement(2374..3792)
                     /locus_tag="VB649_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670424.1"
                     /translation="MYLKYIFKIKDRNLVSDYESLVRNLTINLQKLVIKDITALIGDK
                     QLPITIYYRGENEKFPTGIVKVESDSVEGLELFDKTIKEIVGNESRFGKFTCIYDGIS
                     TYYSTEIYSELHEIERRTQEFLREAFFLSDKSGELKEYQATIKKMDSSDFSFSKLINE
                     IFKASDITDTFIDHVRACVEFGTVPNGDLLPKSFWDSLDNSLLDDKEQGLEINNLLNE
                     IRSTRNTIAHCKEFKKKDYINCIEQVKKLKQALDKIIASIESTDISKMSREVSRINNS
                     LQADNDYIKQKYFIEYDIFEKDILARTGLLEIDWENVSDDIEPLKIHRNFYESISEKT
                     DSEVIEEIKNLEDINFTDEKGNDLDDLTIIVPAQDEGFKRVFLGQREWYDIRIGKSKS
                     NRIKYIAGYEVAPESGVKYWAEVDKIVPSDNYVGYWKVIFKGEVKEYSEYKRLGNTWP
                     PQNSRYVSKKALDEAKYLSDVF"
     gene            complement(3794..4867)
                     /gene="purK"
                     /locus_tag="VB649_001481"
     CDS             complement(3794..4867)
                     /gene="purK"
                     /locus_tag="VB649_001481"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEP1670425.1"
                     /translation="MNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPTNDCPASRV
                     SEVIVAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNR
                     IFEKDFLANKAGVTVAPYKVVTSSLDLGGLDFTKTYVLKTATGGYDGHGQKVIRSAED
                     LPEAQQLANSAQCVLEEFVNFDLEISVIVSGNGEDVTVFPVQENIHCNNILSKTIVPA
                     RISDQLADKAKKMAVQIAKKLQLSGTLCVEMFATADDIIINEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPTIHLHAPAVMLNVLGQHVQQAIDYVAQNPSAHLHMYGKLE
                     AKHNRKMGHVTVFSDLPDEVEEF"
     gene            complement(4854..5345)
                     /gene="purE"
                     /locus_tag="VB649_001482"
     CDS             complement(4854..5345)
                     /gene="purE"
                     /locus_tag="VB649_001482"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001875905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEP1670426.1"
                     /translation="MKTPIISIIMGSKSDWATMQKTAEVLDNFGIAYEKKVVSAHRTP
                     DLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRVLSGLDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSG
                     ELI"
     gene            complement(5623..6888)
                     /gene="purD"
                     /locus_tag="VB649_001483"
     CDS             complement(5623..6888)
                     /gene="purD"
                     /locus_tag="VB649_001483"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEP1670427.1"
                     /translation="MKLLVVGSGGREHAIAKKLLASKGVDQVFVAPGNDGMTLDGLDL
                     VNIVVSEHSRLIAFAKENEISWAFIGPDDALAAGIVDDFNSAGLRAFGPTKAAAELEW
                     SKDFAKEIMVKYNVPTAAYGTFSDFEKAKAYIEEQGVPIVVKADGLALGKGVVVAETV
                     EQAVEAAQEMLLDNKFGDSGARVVIEEFLDGEEFSLFAFVNGDKFYIMPTAQDHKRAF
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVETIVKPVLEGMIAEGRPYLGVLYAGLILT
                     ADGPKVIEFNSRFGDPETQIILPRLTSDFAQNIDDIMMGIEPYITWQKDGVTLGVVVA
                     SEGYPLDYEKGVPLPEKTDGDIITYYAGVKFAENSELLLSNGGRVYMLVTTEDSVKAG
                     QDKIYTQLAQQDTTGLFYRNDIGSKAIRE"
     gene            7141..8265
                     /locus_tag="VB649_001484"
     CDS             7141..8265
                     /locus_tag="VB649_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEP1670428.1"
                     /translation="MKKFHRFLVSGVILLGFNGLVPTMPSTLISQQENLVHAAVLGDN
                     YPSKWKKGNGIDSWNMYIRQCTSFAAFRLSSANGFQLPKGYGNACTWGHIAKNQGYPV
                     NKTPSIGAIAWFDKNAYQSNAAYGHVAWVADIRGDTVTIEEYNYNAGQGPERYHKRQI
                     PKSQVSGYIHFKDLSSQTSHSYPRQLKHISQASFDPSGTYHFTTRLPVKGQTSIDSPD
                     LAYYEAGQSVYYDKVVTAGGYTWLSYLSFSGNRRYIPIKEPAQSVVQNDNTKPSIKVG
                     DTVTFPGVFRVDQLVNNLIVNKELAGGDPTPLNWIDPTPLDETDNQGKVLGDQILRVG
                     EYFTVTGSYKVLKIDQPSNGIYVQIGSRGTWVNADKANKL"
     gene            complement(8323..9870)
                     /gene="purH"
                     /locus_tag="VB649_001485"
     CDS             complement(8323..9870)
                     /gene="purH"
                     /locus_tag="VB649_001485"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEP1670429.1"
                     /translation="MTKRALISVSDKSGIVDFAKELKNLGWDIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDADSHLQAAKDNNIELIDLVVVNL
                     YLFKETILRPDITYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADA
                     GQTTFETRQRLAAKVFRHTAAYDALIAEYFTTQVGEAKPEKLTITYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVVLKHM
                     NPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSY
                     SEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQV
                     VTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQA
                     KDHLDGAVLASDAFFPFADNIEEIAAAGIKAIIQPGGSVRDQDSIDAANKHGLTMIFT
                     GVRHFRH"
     gene            complement(10054..10608)
                     /gene="purN"
                     /locus_tag="VB649_001486"
     CDS             complement(10054..10608)
                     /gene="purN"
                     /locus_tag="VB649_001486"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEP1670430.1"
                     /translation="MKIAVFASGNGSNFQVIAEQFPVSFVFSDHRDAYVLERAQNLAI
                     PSFAFELKEFENKVAYEQAIVDLLDKHEIDLVCLAGYMKIVGETLLLAYEGRIINIHP
                     AYLPEFPGAHGIEDAWEAGVDQSGVTIHWVDSGVDTGQVIQQVRVPRLADDSLESFET
                     RIHETEYQLYPAVLDSLGVERKVI"
     gene            complement(10776..11798)
                     /locus_tag="VB649_001487"
     CDS             complement(10776..11798)
                     /locus_tag="VB649_001487"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEP1670431.1"
                     /translation="MSEKNAYAKSGVDVEAGYEVVERIKKHVARTERAGVMGVLGGFG
                     GMFDLSKTGVKEPVLVSGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNNPVKFEEVVSGVAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAV
                     GVAEKSQIIDGSKVKEGDILLGLASSGIHSNGYSLVRRVFADYTGKELLPELEGKQLK
                     DVLLEPTRIYVKAALPLIKEELVNGIGHITGGGFIENIPRMFADDLAAEIDEDKVPVL
                     PIFKALEKYGDIKHEEMFEIFNMGVGLMLAVSPENVNRVKELLDEPVYEIGRIIKKAD
                     ASVVIK"
     gene            complement(11826..13280)
                     /locus_tag="VB649_001488"
     CDS             complement(11826..13280)
                     /locus_tag="VB649_001488"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEP1670432.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     VSNDNGKLYGYRNVGLLSEVFKNQSELDNLTGNAAIGHVRYATAGSADIRNIQPFLYK
                     FHDGQFALCHNGNLTNAISLRKELEKQGAIFNASSDTEILMHLIRRSHNSSFMGKVKE
                     ALNTVKGGFAYLLMTENKLIAALDPNAFRPLSIGQMQNGAWVISSETCAFEVVGAKWV
                     RDVEPGEVILIDDSGIQCNRYTDETQLAICSMEYVYFARPDSTIHGVNVHTARKNMGK
                     RLAQEFKQDADIVIGVPNSSLSAAMGFAEESGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMIDDSIVRGTTSRRIVGLLREAGASEVHVAIASPELKY
                     PCFYGIDIQTRRELISANHAVDEVCDIIGADSLTYLSLDGLIESIGLETKAPNGGLCV
                     AYFDGHYPTPLYDYEEEYLRSLEEKTSFYIQKVK"
     gene            complement(13441..17166)
                     /locus_tag="VB649_001489"
     CDS             complement(13441..17166)
                     /locus_tag="VB649_001489"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEP1670433.1"
                     /translation="MNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKDLRIVQVYDV
                     FNLAEDLLARAEKHIFSEQVTDRLLTEAEITAELDKVAFFAIEALPGQFDQRAASSQE
                     ALLLFGSDSQVKVNTAELYLVNKDIAEAELEAVKNYLLNPVDSRFKDITLPLEEQAFS
                     VSDKTIPNLDFFETYKADDFAAYKTEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKESWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITTPIAETRAGKFPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPSDVDAFIA
                     ACNKENIDAVVVATVTEKPNLVMTWNGETIVDLERRFLDTNGVRVVVDAKVVDKDLTV
                     PEARATSAETLEADTLKVLSDLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTES
                     SVQKLPVQHGVTTTASVMAQGYNPYIAEWSPYHGAAYAVIEATARLVATGADWSRARF
                     SYQEYFERMDKQAERFGQPVSALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLV
                     AFGVTTADSRKVLSPEFKAAGENIYYIPGQAISEDIDFDLIKANFSQFEAIQAQHKIT
                     AASAAKYGGVLESLALMTFGNRIGASVEIAELDSSLTAQLGGFVFTSAEEIADAVKIG
                     QTQADFTVTVNGNDLAGASLLAAFEGKLEEVYPTEFEQTDVLEEVPAVVSDTVIKAKE
                     TIEKPVVYIPVFPGTNSEYDSAKAFEQVGTSVNLVPFVTLNEVAIAESVETMVANIAK
                     ANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRAAIDSFIEKGGLIIGICNGFQALVK
                     SGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRIANTNSPWLAGVEVGDIHAIPVS
                     HGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSKYNPNGSVNAIEGITSKNGQI
                     IGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK"
     gene            complement(17290..17994)
                     /locus_tag="VB649_001490"
     CDS             complement(17290..17994)
                     /locus_tag="VB649_001490"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEP1670434.1"
                     /translation="MTNQLIYKGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDG
                     KGALNNQISSLIFEKLNKAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVIAGSFSK
                     RFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHVKFLGIVNDEEIAYLKGETRRINEL
                     LKGWFAQIGLNLIDFKLEFGFDQEGTIILADEFSPDNCRLWDKNGNHMDKDVFRRDLG
                     NLTDVYQVVLEKLIAL"
     gene            complement(18136..18387)
                     /locus_tag="VB649_001491"
     CDS             complement(18136..18387)
                     /locus_tag="VB649_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677191.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEP1670435.1"
                     /translation="MTRQEIFERLINLIQKQRSYLSVAITEQTHLKNDLAVDSIELVE
                     FIINVEDEFHIAIPDEDVEDMVFMGDVLDYLVQRLTQLE"
     gene            complement(18380..19387)
                     /gene="plsX"
                     /locus_tag="VB649_001492"
     CDS             complement(18380..19387)
                     /gene="plsX"
                     /locus_tag="VB649_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEP1670436.1"
                     /translation="MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKIN
                     SYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTG
                     ALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSF
                     YAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVA
                     DVIVSDGFTGNAVLKSIEGTAVSIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLD
                     YSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVN
                     D"
     gene            complement(19490..20245)
                     /gene="recO"
                     /locus_tag="VB649_001493"
     CDS             complement(19490..20245)
                     /gene="recO"
                     /locus_tag="VB649_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEP1670437.1"
                     /translation="MQLTESLGIVLFNRNYREDDKLVKIFIEVAGKQMFFVKHISRSK
                     MSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAI
                     ADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDL
                     PLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKL
                     RQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK"
     gene            complement(20431..21393)
                     /locus_tag="VB649_001494"
     CDS             complement(20431..21393)
                     /locus_tag="VB649_001494"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEP1670438.1"
                     /translation="MSYSDLKLFALSSNKELAEKVASAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGEDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGNVSGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQRSAIEKLIVL
                     DTIYLPKERLIDKIEQISIADLVAEAIIRIHEKRPLSPLFEMGN"
     gene            complement(21646..22842)
                     /locus_tag="VB649_001495"
     CDS             complement(21646..22842)
                     /locus_tag="VB649_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEP1670439.1"
                     /translation="MKKRILSAVLVSGVTLGAATTVGAEDLSTKIAKQDSIISNLTTE
                     QKAAQNQVSALQAQVSSLQSEQDKLTARNTELEALSKRFEQEIKALTSQIVARNEKLK
                     NQARSAYKNNETSGYINALLNSKSISDVVNRLVAINRAVSANAKLLEQQKADKVSLEE
                     KQAANQTAINTIAANMAMAEENQNTLRTQQANLEAATANLALQLASATEDKANLVAQK
                     EAAEKAAAEALAQEQAAKVKAQEQAAQQAASVEAAKSAITPAPQATPAAQSSNAIEPA
                     ALTAPAAPSSRPQTSYDSSNTYPVGQCTWGAKSLAPWAGNNWGNGGQWAYSAQAAGYR
                     TGSTPMVGAIAVWNDGGYGHVAVVVEVQSASSIRVMESNYSGRQYIADHRGWFNPTGV
                     TFIYPH"
     gene            23591..23872
                     /locus_tag="VB649_001496"
     CDS             23591..23872
                     /locus_tag="VB649_001496"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP1670440.1"
                     /translation="MTVLNYVNAGDAKSIHNHLFHYTRQVRRHVKVITIGILSAHYYE
                     ITMLFLQAKIILDCFHIPQRLRQAITRFRIRIINTSAIKPIAYRTLKLY"
     gene            complement(24353..24440)
                     /locus_tag="VB649_001497"
     tRNA            complement(24353..24440)
                     /locus_tag="VB649_001497"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24404..24406),aa:Ser,seq:gct)
BASE COUNT         7230 a         5442 c         4289 g         7486 t
ORIGIN      
        1 gacatttttg tcctgttaat aacttttaac atctttttcc cactcttgaa ttaacttgtt
       61 ttccaaatac tgatcagctg tcatttgggc gaacaaacat gccttcataa atgattgttc
      121 tgcttttatt atatcttttt gtttgattaa aaaatatttc cattctatta gttttaaaat
      181 aggcattcta ttccaatctt gaattttcgc cataattttt tgactcattt caatcgcttt
      241 ttctaaatta tcaagtcggt tattttttaa gcttagtgat gaaatatcaa tgataatctt
      301 attaactata aataattcat ctaattcaaa ttgttcaaat tgttctgata gattatctaa
      361 taaagaatca taaaaaatct tatctgaata ttgtccatcc attccctcaa tatcaagata
      421 agctaaatat aattctagaa gtattaaatc attttgccta aagcgtacct tagtctttat
      481 ttgattaaaa tattcttgaa gtaagtcaat gccaaagtta gtattctcac tcaataaagt
      541 atctaaagtt gcctgtaaac aatcaatgat tattttctct tcctctggta atttatcata
      601 ataatcctca aaaatttcat caaactgctc ttctcgtact tgtaattttc catcatccat
      661 gtaagttggt gtccttaaga taaggtattt taattctttg taacgcttag gtagttctaa
      721 atcagcacca tcagttaagt aaccgacact aacgtttaag gcttttgcaa taaaaataac
      781 cttacttaaa cttggtatgg attgacctag ttctatccgt gctaattgac gaacagaaag
      841 ttcagactca tccccacaca agtcctcgcg actaatcctc ttttcaagtc ttaacacttt
      901 tacttttcca ccaaaatgtt ctaacatggt ttctctccaa caactgtttt ctttattata
      961 tcacagcgtc taatcaaaaa aactaacctt tttaatattt ttaaagaaaa tattcgtttt
     1021 tttaaacaaa aaaagaaggg aatcaccttc ttttttttat attaaatccc taaacgctta
     1081 aaaatatcat caacacgttt tgtgtaataa atcggattaa atagttcatc aatttcttct
     1141 tgtgtaagac aagaggtaac tttgatgtct tcttctaaaa gtggtttgaa atccacttga
     1201 ttgtcccagg aataagctgt cttaggttga actaagtcat aagcttcttc tcgtgtcatt
     1261 cctttttcaa tcaatttgag cataacacgt tgactataaa tcaaaccaaa agttgattcc
     1321 atattgcgca tcatattttc cgggaagaca gtcaagttct taacgatatt gccaaagcgg
     1381 ttgagcatgt agtcaatcaa gatagttgtg tcaggtgtga tgatacgctc agctgatgag
     1441 tgtgaaatat cacgctcatg ccaaagtgac acgttctcat aagctgtcac catgtgacca
     1501 cgaatcacgc gcgctagccc tgtcatgttc tctgaaccga ttgggttgcg tttgtgaggc
     1561 atagcagagc tacctttctg acctttggca aagaattctt caacttcacg ttgttctgac
     1621 ttttgcagac ctcgaatctc tgttgccata cgttcgatag atgttgcaat acttgcaagc
     1681 actgcaaaat attctgcgtg aaggtcacgt ggaagaactt gtgttgaaat ttcttgcgga
     1741 cgaatgccta atttgtcaca gacatattgt tccacaaaag gtgggatgtt ggcaaagtta
     1801 ccaacggcac ctgaaatctt accagcttcc acacctgcgg cagcatgttc aaaacgctca
     1861 atattacgtt tcatctcgct gtaccaagtc gccaacttaa gaccgaaagt cgttggctcg
     1921 gcgtgaacac cgtgggtacg acccatcatg atggtcattt tgtgctcacg cgccttgtct
     1981 gccacgatat tggtgaaatt ctcaagatcg cgacggataa tgtcgttagc ttgcttgtag
     2041 aggtaaccgt aggcagtgtc caccacgtca gttgacgtca aaccgtagtg cacccacttg
     2101 cgctcctcac caagcgtttc agaaaccgca cgcgtgaaag ccaccacatc gtgacgtgtg
     2161 tcctgctcaa tctcaagaat gcggtcaatg tcaaaatccg ccttctcacg aatcttagcc
     2221 acatcctcct taggaatctc acccaactct gcccatgcct cgtcagccag aatctcaacc
     2281 tccaaccaag cacggtattt attttcctct gtccaaattg ccgccatctc agggcgtgaa
     2341 taacgttcga tcattttgtt ttttctcctt taattaaaaa acatccgata aatatttagc
     2401 ttcatctaaa gcctttttag atacgtatct actgttttga gggggccaag tatttcctaa
     2461 tcttttatat tctgaatatt ccttcacctc tcctttaaaa attactttcc agtaaccaac
     2521 atagttatct gaaggaacta ttttatccac ttcagcccag tactttacac cactctctgg
     2581 tgcaacttca tatcctgcga tatatttaat cctattgctt ttcgattttc ctatccgtat
     2641 atcataccat tctcgttgac ctagaaagac tcttttaaat ccttcgtctt gcgcaggaac
     2701 aataatggtt aagtcatcca aatcattacc cttttcatca gtgaaattta tatcttctaa
     2761 atttttgatt tcttctataa cttcagaatc tgttttttca ctaattgatt cataaaagtt
     2821 acgatgtatc tttaagggct ctatgtcatc agaaacgttt tcccaatcaa tttctaataa
     2881 ccctgtccta gctaatatat ccttttcaaa aatatcatat tctataaaat atttttgttt
     2941 gatgtagtca ttatcggctt gtaaggagtt atttatgcgt gacacttctc gtgacatttt
     3001 agaaatatct gtagactcta tagaggctat tattttatcc aatgcttgct ttaatttttt
     3061 aacttgttct atacaattaa tataatcctt ctttttaaac tctttacagt gagctattgt
     3121 atttcttgtt gaacgaatct catttaataa attattaatc tctaaacctt gctctttatc
     3181 atctagtaaa gagttatcta aactatccca aaaacttttt ggtaataaat ctccatttgg
     3241 aactgttcca aattcaacac acgctctaac atgatcaata aatgtatcag ttatatcgct
     3301 tgctttaaaa atttcattaa ttaatttgct gaatgagaaa tcactactat ccattttttt
     3361 gatagttgcc tgatattctt tcaattctcc acttttatcg ctcagaaaaa atgcttctct
     3421 taaaaactct tgtgttcgac gctcaatttc atgaagttca gaataaattt ctgttgaata
     3481 atatgtactt attccatcgt atatacatgt gaactttcca aatctacttt cattcccaac
     3541 tatttccttt atcgttttat caaataactc taatccttca actgagtctg attcaacttt
     3601 tactattccc gtaggaaact tttcattctc cccacgataa tatatcgtaa ttggaagttg
     3661 tttatcccct attaatgcag ttatatcttt aataactagt ttttgaagat tgattgtcaa
     3721 atttcgaact aaagattcat aatccgatac taaattccta tcctttattt taaatatata
     3781 ctttagatac atcctaaaac tcctccacct catcaggcaa atcactaaac accgtcacat
     3841 gtcccatttt gcggttatgt ttcgcttcta gtttaccata catgtggagg tgggcgctag
     3901 ggttttgggc aacatagtca attgcctgct ggacgtgttg tccgaggaca ttgagcatga
     3961 cggctggagc atggaggtgg atggttggga gcggcgctcc tagcacgccc aaaatgtggg
     4021 tgtcaaactg tgaaaagtcg caagcctcga ttgagtagtg ccctgagttg tggggacgtg
     4081 gggcaatttc attgataatg atatcatctg cggtcgcaaa catttccaca cagagagttc
     4141 ctgacagctg gagtttcttg gcaatctgca ccgccatttt cttagcctta tcagccagtt
     4201 gatctgagat acgagctggc acgatagttt ttgacaggat attgttgcag tggatatttt
     4261 cctgaacggg aaagaccgtc acatcctctc catttccaga cacgatgact gagatttcaa
     4321 ggtcaaagtt gacaaactct tccaagacac actgagctga gttagctaat tgctgcgcct
     4381 ctggcaaatc ttctgctgag cggataacct tttgcccatg accgtcataa ccacctgtcg
     4441 ctgtcttgag gacataggtc ttggtaaaat caagtccccc taggtcaagg ctagacgtca
     4501 ccaccttata gggagcaaca gtcacaccag ccttatttgc cagaaagtct ttttcaaaga
     4561 tacggttttg ggaaatgcgg agcagatcgg tcccctgcgg tagctgacaa gctgacacaa
     4621 cggcatccaa accgtccgca tcaacattct caaactcata agtcaacaca tcgcaacgcg
     4681 cagccaattg tcccaaagcc tcaacatcat cgtaaggcgc cacaattacc tcgctaacgc
     4741 gggaggcagg gcagtcgtta gtaggatcca gcgtgatgac cttgtggccc atatagatgg
     4801 ccgcaattgc catcatctgc cctagctgac caccaccaat aatcccaata gtcttaaatg
     4861 agttcaccac ttgactcctc tgcgattttt ccttgttcct catggaaatg agctagcgca
     4921 tcagccagat tttggtcctc gatagaaagg atacggaggg ctgtcagggc agcgttagtc
     4981 gctcccgctt ctccgatagc catggttgcc acaggcacac cgccaggcat ctgcacaatg
     5041 gaatagagcg aatccaaacc tgaaaggaca cgtgatttga ctggcacacc gataacaggc
     5101 agcgttgttt tagctgccac cataccaggc aagtgagctg ccccacctgc tcctgcgatg
     5161 atgattttga tgccacgacc acgtgcttcc tcagcatgct tgaacatgag gtcgggcgta
     5221 cggtgagcag agacgacttt cttctcgtaa gcaatgccaa agttgtctag aacttcagcc
     5281 gttttttgca tggttgccca gtcagatttg gagcccatga taatagaaat aattggagtt
     5341 ttcataatta agatacaaag gggcgtttcg acttgtcgaa actttccgta gaaaaatatg
     5401 cggtaagtcc gaaatctttg atttcgaaga cgaacccacg tcagggcgac taggtgcttt
     5461 agcatcagac gcctacgacg cagaaaacta acgatgacgc ttgcgtccag gtagttttat
     5521 ttttttccta ggaaattagt cccgtgttca gttcctttct tctttctttt tggagcgacc
     5581 ttcggtcgtt gattgctgac gctaatattt gaatggttag tcttattctc ttatagcttt
     5641 gcttccgatg tcatttcggt agaagagacc tgttgtgtct tgttgggcca gttgggtata
     5701 gattttgtcc tgccctgctt tgacgctgtc ttctgtggtg acgagcatat agacacgtcc
     5761 tccgtttgag agaagtagct cgctattttc cgcaaactta actcctgcgt agtaggtgat
     5821 gatatcgccg tcggtctttt caggcagtgg cacacctttc tcataatcga gtggatagcc
     5881 ttctgatgca acgacaacgc caagagtcac gccgtccttc tgccaagtga tgtaaggctc
     5941 aatgcccatc atgatgtcgt cgatgttctg agcgaaatca gaagtcaggc gagggaggat
     6001 aatctgagtt tcagggtcac cgaaacgtga gttgaactcg ataaccttag ggccatcagc
     6061 tgtcaggata agccccgcat agaggacacc tagataagga cgcccttcgg caatcatacc
     6121 ttcaaggaca ggcttaacga tggtctcaac cgctgtatcc accacgctct gaggcaggtg
     6181 gggaacaggc gcataggcac ccataccacc agtgtttggc cccttgtctc cgtcaaaggc
     6241 acgcttgtga tcctgagctg tcggcatgat gtagaactta tcaccattaa caaaggcaaa
     6301 gagggaaaac tcctcgccat ccaagaattc ctcgataacc acacgcgctc ctgaatcgcc
     6361 aaacttattg tccagaagca tctcttgcgc cgcctctacc gcctgctcaa cggtttcagc
     6421 cacgaccaca cccttaccta gcgccaagcc atcagccttg accacgatag gtacgccctg
     6481 ctcttcgatg taggctttgg ctttttcaaa gtctgaaaat gtgccatagg ctgctgttgg
     6541 gacattgtac ttgaccatga tttccttggc aaagtctttt gaccactcta gctccgctgc
     6601 tgcctttgtt ggaccaaaag ctctgagtcc agcactgttg aaatcatcaa cgataccagc
     6661 tgctagcgca tcatcaggac caataaaggc ccaagaaatc tcattctcct tagcaaaggc
     6721 aatcaacctg gaatgttcgg aaactactat attcaccaag tccagaccat ccaaggtcat
     6781 accatcatta ccaggtgcca caaaaacctg atccacaccc ttagacgcta acaacttctt
     6841 agcaatcgca tgttcacgac cacctgaacc aacaacaagt aatttcaaaa catccacctc
     6901 tttcgtatta taattagata ttatatcata aacgttcgct tttttacata atgtattagt
     6961 tatcaataat tgaaacattg taaaaatgtg atagtagacc acaattcttg aaataaggaa
     7021 cactctatta gctaatcaaa cagttattta atatcaagta aagccaattt tcaaaataat
     7081 catctaaaaa taacattttt tgtttcttgc tttcgaataa taagttacag gaggtaatta
     7141 atgaaaaaat ttcatcgttt tttggtctca ggagtaatcc ttttaggttt taatggtcta
     7201 gtacctacta tgccatctac acttatttcg caacaggaaa atcttgttca tgcagctgtt
     7261 ttaggcgata actatccgag taagtggaaa aaaggcaatg gaatcgattc gtggaacatg
     7321 tatatccgcc aatgcacttc ttttgcagct tttcgtttaa gctctgctaa tggttttcag
     7381 ttacctaaag gctacggtaa tgcctgcacg tggggacata tcgcgaaaaa tcagggttat
     7441 cctgtgaata agacaccaag cataggggct atcgcttggt ttgataaaaa cgcttatcag
     7501 tcaaatgctg cttacggtca tgtagcatgg gtagctgata tccgtggaga cactgtcact
     7561 atcgaagagt ataattacaa cgctggacaa ggccctgaaa gataccataa gcgtcaaatt
     7621 ccaaaatctc aggtaagtgg ttatatccat tttaaagact tatcatctca gacaagtcat
     7681 tcctacccaa gacaactaaa acacatttct caagcttcat ttgacccctc tggaacttat
     7741 cactttacaa ccagattacc agtcaaagga caaaccagta tcgatagccc tgatcttgct
     7801 tactatgaag caggtcaatc tgtttattac gataaagtcg tgactgctgg aggttacaca
     7861 tggcttagct acctcagttt ttctggaaac cgacgctata ttcccattaa agagcccgca
     7921 cagtctgtgg ttcaaaatga caatacaaaa ccttccatta aggtcggtga tactgttacc
     7981 ttccctggcg tttttcgtgt agatcagctt gttaataatt tgatcgttaa taaagaatta
     8041 gccggaggag acccaactcc actaaactgg attgatccca caccattaga tgaaacagat
     8101 aaccaaggaa aagttttagg agatcaaatt ctccgtgtgg gtgaatattt taccgtcact
     8161 ggtagttata aagtattaaa aattgatcaa ccaagtaatg gtatttatgt tcaaatcgga
     8221 tctcgtggaa catgggtaaa tgctgataaa gctaacaaat tatagttaac ttatattttc
     8281 ttttaataaa aaatgtggtt ttaattagac cacatttttt tattaatgcc taaaatgtct
     8341 cacacctgtg aagatcatgg tcaagccatg tttgtttgcg gcgtcaatag agtcttggtc
     8401 acgaactgaa ccacctggtt ggatgattgc tttgatccct gcggcagcga tttcttcaat
     8461 gttgtccgca aatgggaaga aggcatctga tgctagaacg gcaccgtcaa ggtggtcttt
     8521 agcctgctcg atagcaatct tgactgagcc gacacggttg gtttgacctg caccgagtcc
     8581 aagcgtcatg tgatcgttag taataataat cccgttagac ttaacatact tgatagcctt
     8641 ccaggcaaac tcaagggcag tcgcctcttg ttctgttggt tggcggtctg tcaccacttg
     8701 ccagtcagat ggattttcag ccacaacgtc ttggttttgc accaaaagtc caccaactac
     8761 gccagtgtac tcagcttcca cttcgctggc agcttgggca tcaaacggca actcaaggat
     8821 tcgcaagttt ttctttttat ttgtgagaat agctagcgct tcttctgagt atgatggtgc
     8881 gatgatgatt tccaagaaga tagggtgcat cttcttagct gtcgctgcgt caacttcacg
     8941 gttaaggacg acaattccac caaagattga aactgggtca gcttcataag cgtaatccca
     9001 agctgtctca atatcatcag cctgtccgat accacatggg ttcatgtgtt tgaggacaac
     9061 aacagttgga cgatctttga aatcacggat aatacggatt gctgcatcgg catcacggat
     9121 attattgaag gacaattctt ttccgttgag ctgtttagca gaagcaattg agtagtctgt
     9181 tggcaaggct ttttgataga aatcagcgtc ttgttgtgga ttttctccgt aacgcatagc
     9241 ctgtttaagg tcgtaagtga tggttaattt ttcaggctta gcctctccca cttgagttgt
     9301 gaagtactca gcaatcaaag cgtcgtaggc tgctgtgtga cgaaagacct tagctgccaa
     9361 gcgttgacgc gtttcaaatg tcgtctgacc agcgtcagcc aattctccca aaacagtcgc
     9421 ataatccgct gggtcaacca caacggtcac gctagcgtga tttttagcgg ctgagcgaag
     9481 cattgatgga ccgccgatgt cgatgttttc caccgccaaa tcataggtta tgtctggacg
     9541 aaggatagtc tccttgaaga gatagaggtt gacaaccacg aggtcaatca gctcgatatt
     9601 gttgtcctta gcagcctgaa ggtggctgtc agcgtcgcga cgagccaaaa gcccaccgtg
     9661 aatgtttggg tggagggtct taacacgacc gtccatcatc tctgggaatc cagtcacatc
     9721 gtcgatggca atggtctcaa cgccagcatt atcaagggca accttagtcc caccagttga
     9781 gataatatcc caacccaagt ttttcaattc ttttgcaaag tcaacaattc ctgacttgtc
     9841 agacactgag attaaagcac gtttagtcat atttaagata ccaagtccga ctagaaggcc
     9901 aaggaaaaat aggaaactcg acgaagacgc ttgcgcctag gagatgttta tcttttttct
     9961 gtgccttcca gacgggttca attcctttct ttttggaacg ttaattcttc tttactatct
    10021 ttcctaactt tacctaaaat tttaagataa aggctagatt actttcctct ccactcccaa
    10081 gctatctaag acagctgggt agagttgata ttcggtttca tggatacggg tttcaaagct
    10141 ttctaggcta tcgtctgcta ggcgtggtac gcgcacttgt tggatgacct gaccggtatc
    10201 cacaccagag tcaacccagt ggatggtcac gccagactgg tcaacaccag cttcccaagc
    10261 atcctcgata ccgtgggcac ctggaaattc aggcaggtag gctgggtgaa tattgataat
    10321 acgcccctca taggccaaga gtaaggtttc tccaacaatc ttcatatagc ccgccagaca
    10381 gactaagtca atctcgtgtt tgtccaacaa atcaacgatg gcttgctcgt aagccacctt
    10441 attctcaaac tccttgagtt caaaagcgaa gcttggaatg gctaaattct gagcacgctc
    10501 taaaacatag gcatcacgat gatctgaaaa gacaaaacta actggaaact gctctgctat
    10561 gacctgaaag ttggaaccat taccagaagc aaaaacagcg attttcatat tcgatacaaa
    10621 gggatgattc ggcttgccga aaaatttcgt agaaaaatag gaaaacgaac aacgacgctt
    10681 gcgtctaagt cattttatct tttttcctag aaatttaatc ccgtgttcag ttaggcaaac
    10741 taactaaaca ctcctttctt ataaaattta gtgacttatt taatcaccac actagcgtct
    10801 gctttcttga tgatacgacc gatttcataa actggttcat ccaagagctc tttgacgcgg
    10861 ttaacatttt caggactaac agctagcata agaccgacac ccatattgaa gatttcaaac
    10921 atttcttcgt gcttgatgtc accatatttt tcaagcgcct tgaaaatcgg aagcactggc
    10981 accttgtcct catcgatttc cgcagccaaa tcatccgcaa acatacgagg aatattctcg
    11041 ataaagccac cacccgtgat gtggccgata ccgttgacta gttcttcctt gattaatggc
    11101 agagctgctt taacatagat acgagttggc tcaaggagga catccttaag ttgtttgcct
    11161 tcaagctctg gaagcagctc tttaccagta tagtcagcaa agacacgacg taccaaagaa
    11221 taaccgtttg aatggatacc acttgaagca agtcccaaaa gaatatcgcc ttcttttact
    11281 tttgaaccgt cgatgatttg agatttttca gccacaccaa cagcaaagcc tgcaaggtca
    11341 taatcatctt gaccatacat tccaggcatt tcagcggtct cacctccaat gagtgctgct
    11401 cctgcttgaa cacaaccttc tgcaacgcca gaaacaactt cttcaaattt gactggatta
    11461 ttttttcctg tcgctacgta gtcaaggaag taaaggggct cagcacctgc tgcaataata
    11521 tcattgacac acatggcaac acagtcttga ccgattgtgt cgtgcttgtc gtacttgata
    11581 gcaagcataa gttttgttcc gacaccgtca gtccctgaaa ccaagacagg ctctttaact
    11641 cctgttttac tcaagtcaaa catcccacca aagccaccta gaactcccat aactcccgca
    11701 cgttctgtac gagcaacgtg tttttttatt ctttcaacca cttcataacc agcttcaaca
    11761 tcaacaccag attttgcata agcatttttt tcagacatgt tttctcctta tataattagc
    11821 agagcttatt tcactttttg aatataaaaa cttgttttct cttctaaact tctgaggtat
    11881 tcttcttcat aatcataaag cggtgttgga taatgcccat caaagtaagc tacgcataaa
    11941 ccaccatttg gtgcttttgt ttcgagtcca attgattcaa tcaacccatc cagtgagaga
    12001 taggtcagac tatctgcgcc aataatatca cacacttcat caacagcgtg atttgctgaa
    12061 atcaactcac gacgagtctg aatatcaata ccataaaaac aaggatactt taattctgga
    12121 ctagctatag caacatgtac ttcactagct cctgcttctc ttaataatcc gacaatcctt
    12181 ctagaagtcg ttcctcttac aattgagtca tcaatcataa caacgcgctt tcctttgaca
    12241 acaccagata ccgctgatag tttcattcga acaccttgtt cccttaattc ttgtgtcggt
    12301 tgaataaagg ttcgctgcgt atactgattt tttacaagac ccatctcatt tggtaatccg
    12361 gattcttcag caaagcccat agcagccgat aaggacgaat ttgggacacc aattacaata
    12421 tcagcatcct gtttaaattc ttgtgcaaga cgctttccca tattttttcg agccgtatga
    12481 acattaacac catgtatagt tgaatccggc cttgcaaaat agacatattc catcgaacaa
    12541 attgccagtt gcgtttcatc agtataacga ttacattgaa taccactatc gtctataaga
    12601 ataacttcgc caggttcaac atctctaacc cattttgcgc ctaccacctc aaaagcacag
    12661 gtctcactgg aaataaccca ggcaccattt tgcatttgtc caattgacaa aggacgaaag
    12721 gcattagggt caagagcagc aatgagttta ttttctgtca tcagtagata ggcaaagcca
    12781 ccctttactg tatttagagc ttcttttacc tttcccatga aacttgagtt atggcttcga
    12841 cgaatcaagt gcatcaaaat ttcagtatct gaggaggcat tgaaaattgc accttgcttt
    12901 tctaattctt tccttaagga aatagcattt gtcaaattac cattatggca taaagcaaat
    12961 tgcccgtcat gaaatttata aagaaaaggc tgaatattgc gaatatctgc agaacctgca
    13021 gtagcatacc gaacatgtcc aatagccgca ttcccagtta aattatctaa ttcagattga
    13081 ttcttaaaaa cttcagaaag gagcccaaca tttcgataac catagagttt cccattgtca
    13141 tttgaaacaa taccagctcc ttcttgaccg cgatgttgaa ggctatgaag cccaaagtaa
    13201 gtgacttgag ctgcctgagg atgtccccag ataccaaaga ctccacattc ttcatttaga
    13261 gattttactt cgtatgtcat ttttacctcg atacaaaggc tgtcaagtaa agcgaaaata
    13321 gaaagttttt cgcacaactt atcgcccgtg tttactattt ctcaaaaatt aagcgagatt
    13381 ctttctaacc tcgcccttca ctaattcaag gcgaaggcta aaaaggttca ctgaaccttt
    13441 ttacttccct gtaaagtatt ttacagcact tgcaaagagg gtttggtctt tgttaccagg
    13501 gatattttgg aagagtccgt cttcccagcg ttctgagtgt cccatcttac cgatgatttg
    13561 accattcttg ctggtaatcc cttcgatggc attgacagag ccgtttggat tgtatttaga
    13621 atccatagat ggttgtccgt caaagtccac atattggctc cagatttgac cattgtctct
    13681 tagctctgca aattcagaag cgctgacaac aaatttacct tcaccatgtg aaactggaat
    13741 ggcatgaata tcgccgacct caactcctgc caaccaaggt gagttggtat ttgcgatacg
    13801 agtctcaacc atcttggcaa catgctgatt agcatcgtta tagaagagag ttggacttgt
    13861 ctcaccagct tcctcgaagt ttccgtatgg aagaagacct gatttaacaa gggcttggaa
    13921 accattacag ataccgatga taaggccacc tttttcgatg aagctgtcaa tagctgcgcg
    13981 gaccttctcg ttaagcaaga tattgacgat aaacttagca gagccatctg gttcatccgc
    14041 tgctgagaaa cctccagcaa agaagatgat atttgcctta gcaatattag caaccatagt
    14101 ctcaactgac tcagcaatag caacctcatt caaggttaca aatggtacca agttgacact
    14161 agttccaacc tgttcaaagg ccttagctga atcgtattct gagttggtac cagggaagac
    14221 tggaatgtaa accactggtt tttcaattgt ttccttagcc ttgataacag tatctgatac
    14281 cacagcagga acttcttcaa gaacatctgt ctgttcaaat tctgttgggt aaacctcttc
    14341 caatttgcct tcgaaggctg ctagaaggct agcgccagca aggtcatttc cattgacagt
    14401 gactgtaaag tctgcctgag tttgaccgat tttcaccgcg tcagcaattt cctcagctga
    14461 tgtaaagaca aaacctccga gttgagctgt caagctgctg tcaagctctg caatttcaac
    14521 agaagcaccg atacggttac caaaagtcat gagagcaaga ctttctagga caccaccgta
    14581 tttagcggct gaggcagctg taatcttatg ttgagcttga atagcctcaa actggctaaa
    14641 gttagccttg ataagatcaa aatcaatatc ttctgaaata gcttgacctg ggatatagta
    14701 aatgttttcg ccagccgctt taaactcagg agagagaacc ttgcggctgt ccgctgttgt
    14761 cacgccgaaa gctaccaagg ttggtggtac tgtcaagtct tcgaaagtac cagacataga
    14821 gtccttaccg ccgattgatg gcaaaccaag ttgaatctga gcctcaatag aaccaagaag
    14881 agctgatact ggctgaccaa aacgctctgc ctgtttatcc atacgctcaa agtactcttg
    14941 gtaagagaaa cgtgcacgag accagtcagc acctgttgct accaagcgag ctgtcgcttc
    15001 aataacagca taggcagcac cgtgataagg tgaccactct gcaatataag gattgtaacc
    15061 ttgagccata acagatgcag ttgttgtcac accatgttga actggcaatt tttgaacaga
    15121 actttctgtc ggtgtgattt ggtaacgacc accgattggg tggttaacgg ttgaacgacc
    15181 aacagatgag tcaaagatgg tttggagacc tttttgacta gcgtggttga ggtcagacaa
    15241 gaccttaagc gtatctgctt caagtgtctc tgctgatgtt gcgcgtgctt ctggaactgt
    15301 caagtccttg tcaacgactt tagcatcaac aacgacacgg acaccattgg tatcaaggaa
    15361 acggcgttcc aaatcaacaa ttgtttcgcc attccaagtc atgacaagat ttggtttttc
    15421 agtaacggtc gcaacaacga ctgcatcgat attttccttg ttgcaggctg cgatgaaggc
    15481 atccacatca cttggacgaa caacgactga catacgctct tgagattctg agattgcaat
    15541 ttcagtacca ttaagacctt ggtatttaag aggcaccttg tccaaatcga tttcaagacc
    15601 gtcagccaat tcaccgatgg caacacagac accacctgca ccgaagtcat ttgatttctt
    15661 gatcagacga gtgacattgc catcacggaa aagacgttga atcttacgtt cttcaatggc
    15721 attccctttt tgtacctctg cgccagctgt ttccacagat tcaaccgttt gaaccttaga
    15781 tgaacctgtc gcaccgccga caccatcacg ccctgtttta ccaccaagca agatgaccac
    15841 atcacctgct tctggttttt cacgaaccac attttcctta ggtgcagcac caaccacagc
    15901 tccaagctcc atacgtttgg ctacgaagcc agggtggaag tactcacgca cataagttgt
    15961 cgcaagccca atttggttac catatgaaga atagccgtgc gccgcagttt tagaaataac
    16021 ttgttgtgga aatttaccag cacgtgtttc cgcaatcgga gtcgtgatat cgcctgcgcc
    16081 tgaaatacgc atagcctgat aaacgtatga acgtcctgac aatgggtcac gaatagcacc
    16141 accgatacaa gtcgccgctc caccgaatgg ctcaatttct gttgggtgat tgtgagtctc
    16201 gttcttaaac atgaggagcc aagactcttt cacaccatca acatctactt caatctcaac
    16261 tgagcaggca ttgatttcat ctgagacttc catatcgtcc agacgaccgt tggcacgctc
    16321 ataacgacca aaaatagtcg ccatatccat aagtgtttgt ggcttttcag aacgaccaag
    16381 ctcatcacgc atggcgatat atttgtcata agttgtctgc aattgttttt ggaatttaga
    16441 agctgaaaaa tcaatgttct tcaattcagt ttcaaaggtt gtgtgacggc agtggtctga
    16501 ccagtaagta tccaaaactt tcaactcagt ctcagttggc acacgtccga ttgatttgaa
    16561 ataatcttgg atgaagagaa ggtcatcgac ctccatagcc aagccctgct ctgtcttata
    16621 ggccgcaaaa tcgtcagcct tataagtctc gaagaaatca agattaggga tcgtcttatc
    16681 agatacagag aaagcctgct cttcaagcgg caaagtaatg tccttgaaac gcgaatcaac
    16741 agggttcaaa agatagttct taacggcttc aagctctgct tctgcaatat ccttattgac
    16801 caagtatagc tcagctgtat tgaccttaac ctgactgtca cttccaaata atagcaaagc
    16861 ttcttgcgaa ctagcagcac gttggtcaaa ttgaccagga agcgcctcaa tggcaaagaa
    16921 ggcaacctta tcaagctccg cagtgatttc agcttccgtc aaaagacggt ctgtcacctg
    16981 ctcagagaaa atatgcttct cagcacgcgc cagtaaatcc tcagccaaat tgaagacatc
    17041 atagacctgc acaatacgca agtccttcaa agaagtcagt tgtagattat gtgtcaactc
    17101 tttcacaagg ctagccgatt taatgccaaa gtcagccttt ttctcaacaa aaatacgttt
    17161 attcatataa gataccaagt ccgacaaggg agcgactgga aaataggagg acatctgaaa
    17221 ttgagatttc agtaagttcc atcttttttt cggagtttcc cgaacggatt caattccttc
    17281 ctcttctagt tacaatgcta tcaacttctc aagtacaact tgatagacat ccgtcaggtt
    17341 gccaaggtct cttctaaaaa catccttgtc catatggtta ccattcttat cccataggcg
    17401 acagttatca ggcgaaaatt catctgctaa gataattgta ccttcttgat caaatccgaa
    17461 ctccaacttg aagtcaatca agttaagccc aatctgagca aaccaacctt tcaagagttc
    17521 attaatacgg cgagtctctc ctttcagata agcaatctcc tcatcattaa caatacccaa
    17581 aaacttcaca tgctcatcat tgataaaagg atcattcaga tcatcatttt tgtagtaaaa
    17641 ttccacaatt ggcgtttcaa gaacacgtcc ttcttccact ccaaaacgtt ttgaaaatga
    17701 gcctgctatc acattccgta acaccacctc aagtggaata atatcaactt ttttattcaa
    17761 ttgttcgttt tttgaaattt gctcaatata atgtgtcacc acaccagcct tatttaattt
    17821 ctcaaaaata agagatgaaa tctgattatt tagtgctccc ttgccatcaa tagtctcctt
    17881 acgagctcca ttcaacatag tagcttggtc tttatagacc gttctaatca cattttcatc
    17941 ttttgtacta taaatatctt tcgcttttcc tttataaata agctggttag tcacttgatt
    18001 attcgccttt ctttctgttt tcatttaaga gtaacatact ctataaaaat attcaagata
    18061 ttgtttacgt ttataagttt ttttaaaaaa aggttcgttt ttaaagaata ataaaaagag
    18121 cttacgctct ttttattatt ctaactgagt caaacgctga actaaataat ctaaaacgtc
    18181 tcccataaat accatatcct caacatcttc atcaggaata gcaatatgaa attcatcttc
    18241 aacattaata ataaattcaa ctagttcaat agagtcaacc gctaaatcat tttttaaatg
    18301 tgtttgttct gtaatagcta cactcaaata gcttctttgc ttctgaatta agttaatcag
    18361 cctttcaaaa atctcctgtc tagtcattta cttgagtctc cttagcaaat tcttctacta
    18421 attgtccgac cacgttagtg tctagcatcg tacgtacttg ttttatcgtt gaaaaaatag
    18481 cttttacatc actagaacca tgagacttta caacaggtgc ctttaaacca aataaaactg
    18541 cacctccagc actagagtag tcaagagtct tcttcatctc gtaaagacta cttttaagta
    18601 gactagctcc aattttagtc ttaataccgc cgctattaat tatctgtttc agttgcccca
    18661 taatgctaac agctgttcct tctattgatt tcaacactgc gtttcccgtg aaaccatctg
    18721 atacaataac atctgcaaca cctgacataa gttctcgcgc ctcgacatta ccaacaaaag
    18781 atattgtatt atctgctgtt aaaagttcat aagtggcctt acgaagggga tctccttttg
    18841 tttcttctgt accattgttt aatagaccaa cacgtggatt agcaatccca cgtacattct
    18901 tagcatagaa agagcctaaa atagcatatt gatgtaaatg ttttgccgta ttttcagcat
    18961 tagctccaag atccaacata tcaaatccta atccggttac tgtgggaata gttgataata
    19021 gtcctggacg atcaactccc ttgatacgcc ccacaacaaa caaacctaca gctaaaagag
    19081 cacctgtatt acctgctgaa ataatggcat ctgcttttcc ttctttcact gccttagctg
    19141 ctaaaaccat tgaagccttc tttttacggc gaacagcttt tgcaggttca tcatctgaca
    19201 taattttttc atctgtatga ataatagcaa cacgatctga ttgaataaga taggagttaa
    19261 tctttgtctg atcaccgtaa agttgaattt cgatatctga aaatgcttct attgcttgat
    19321 taacaccctc aacaatagct ttaggagcgt tatctccacc catagcatct attgcaattc
    19381 tcttcatttc cactccttta attatatctt gtgttcttac acaatctatt aatagtattt
    19441 ttattatagc atattctgaa accaattccc ataaacgaaa gagaccctat catttcataa
    19501 tatctcccca cttaactaaa ttatcaatga atgttttact ttttaatttg attcctacat
    19561 agtcgtgata caactcatca atgaactgac gaagcttctt tttgatgtct ttattcaatg
    19621 aaatagttct caaatcatca aatgtgattt tttgaaatcg actcaacaag tagataacat
    19681 ttggatctaa atgattacgt cggttgtctt tgtaataatg ttcagaacaa agtacagctg
    19741 aaaaacgatg ggaaaaatca agcggtaaat cagtgcgatg acaaatggca cactcatgaa
    19801 agtttagact aataccaaaa cgatctaata tctgaatttc aaaaatattt gtcaaaattt
    19861 cataatctag gccctcttcc atcaaatcaa gtgttttttt caaaaacgta aacaaatgcg
    19921 aatctgattc attatctgca atcgcagcat cagctaatgc taagacataa ctagcatagg
    19981 ctaatcgaaa aatatcatta ttaatatacc gataagtgtt aacgttacta tagtcaacaa
    20041 cataagacaa gcctgtatca tttaacttga aaataaaatc agcaatcgtt agtggttgaa
    20101 tgattgagga cattttggaa cgactaatat gtttcacgaa aaacatctgc ttacctgcta
    20161 cttcaataaa tattttgact aatttatcat cttctcgata attcctatta aaaagaacaa
    20221 tgcctagtga ttctgttagt tgcatattac ctcgtcgtat ttttctctta ccttttatct
    20281 tagtttacaa taaactgttg ttatctttct tattataccc aaaatccttt agaattgcat
    20341 agttcatccc acaataatta ataccacatt acccttacat tttattcaag tcaaaaagcc
    20401 cgagatctat tatctcaggc ttcgttaagt ttaattgccc atctcaaata aaggtgacaa
    20461 cggacgtttt tcatgaatac gaataatcgc ttctgcaacc aaatcagcaa ttgaaatttg
    20521 ttcaatttta tcaataagac gttcttttgg cagataaata gtatcaagaa caattagttt
    20581 ttcgatagcc gaacgttgaa tattatcaag tgctggtcca gaaagaacgg gatgcgtaca
    20641 tgacgcatac acagcagttg cccccgcttc agcaagcgca tctgctgcat ggcaaatagt
    20701 ccctgcggta tcaatcatat cgtcaatcaa gatacatttc ttgcccgaaa catttccgat
    20761 aatattcatc acttcactgg tgttcatctt atccacacta cgacgcttat cgataattgc
    20821 aattggtgtt tggaggaatt gtgctaattt acgcgcacga gtcacaccac catggtcagg
    20881 actaacaacg acaacatctt cacccactaa accatgacga tcaaaatagt ctgcaattaa
    20941 aggtgcaccc atcaagtgat caactggaat atcaaagaac ccttgaattt gagcagcatg
    21001 taaatcaacc gttaataagc gatctacacc agcaacttct aacatattag caactaattt
    21061 tgaagtaata ggttcacgag aacgcgcttt acggtcttgg cgtgcatagc cgtagtaagg
    21121 catcacaact gaaatttttt cagcactagc acgctttaaa gcatcgacca taatcaaaat
    21181 ttccattaaa ttgtcattga caggtgagct agttgattgc aaaataaaga catgatgacc
    21241 acgaattgat tcttcaatat ttacttggat ttcaccatct gaaaactggc gaaccgtaga
    21301 ctttccaagt tgaataccca ttgcagacgc aactttttct gctaattcct tgtttgacga
    21361 taaagcaaac aattttaaat cagaataaga cattttttcc tccaaagttt taatcctata
    21421 ccattttaac gcttttcaag tgaattatca aatgaaattg aaaaaccgtt aaagaatgta
    21481 ttaaatatac cttttatcga ctttatatac ttctcttata ttatacataa gcgattggcc
    21541 aaacaactct cttataaatt aactatatcg tcaatactct cagaactatt ccacaatagg
    21601 aataatcaaa aaggttagaa caactgttct aacctaaata atatgttagt gtggataaat
    21661 aaatgtaaca cctgttggat taaaccaacc acggtgatca gcaatgtact gtctaccact
    21721 gtagttagac tccatcacac gaatacttga ggcactttga acctcaacta caacggcgac
    21781 atgtccataa ccaccatcgt tccaaacggc aatcgcacct accatcggcg ttgaaccagt
    21841 acgataacca gctgcttgag cactataagc ccattgacca ccatttcccc aattatttcc
    21901 tgcccaagga gctaaagatt tagctcccca tgtgcattgt ccaactggat aagtattaga
    21961 agaatcatat gatgtttgtg gtcttgaaga aggagctgcc ggagccgtga gtgcagctgg
    22021 ttcaatagca ttactacttt gcgctgccgg agtagcttgt ggtgctggag taatagcaga
    22081 ttttgctgct tcaacagatg ctgcttgttg tgcagcctgt tcttgtgcct taactttagc
    22141 agcctgttct tgtgctaagg cttcagcagc agctttttct gcagcttctt tttgagctac
    22201 caaattagct ttatcttcag tagcagatgc taattggaga gctaaatttg cagttgcagc
    22261 ttccaaatta gcttgttgag tacgtaatgt attttggttt tcttcagcca ttgccatatt
    22321 agcggcaatg gtattaatag ctgtttggtt agctgcttgc ttttcttcaa gggaaacttt
    22381 atcagctttt tgttgttcta acaatttagc gttagcagag acagctctat taattgctac
    22441 taaacggttt acaacatcag aaattgattt agaattcaaa agtgcattaa tgtaaccaga
    22501 agtttcattg tttttataag cactacgagc ttgatttttt aatttttcat tacgagcaac
    22561 aatttgactt gttagagcct taatttcttg ctcaaatcgc tttgaaagcg cctcaagttc
    22621 tgtatttctt gcggtcagtt tatcttgttc agattgtagt gaacttactt gagcctgtaa
    22681 cgctgaaact tgattctgtg cagctttttg ctctgtagtc agatttgaga taatagaatc
    22741 ttgcttagca atcttagtac ttaaatcctc cgctcctaca gttgtagctg ctccgagggt
    22801 aacaccactt acaagaactg ctgataaaat tctttttttc ataataaaaa aactactcct
    22861 tttcgataag acatcttata ttttaccaaa aaaaaaagta tttaatatta cgcaattgtt
    22921 acagttatat gtaataaaca ataaaaatat tttagggatt atcttataaa agtaaagcag
    22981 ccaaaaagat atatctttca tttaaaatag aatacagtga aatcaattta aatacataaa
    23041 actgtataaa attacacaaa aattttgtat tacttatatc ttaataacgc tataagtaat
    23101 acaaaattgt ttatcttcac tcagacacct tatccttctt agaatgaatt tttagttact
    23161 tatccacagg ttaataactt tttttcgcct aaaacattat ccacaatagt gacattttct
    23221 attatcagtt tatgcctttc cattttccaa ttagaatatt agacatcttt tttgacctta
    23281 tcattattaa tataagtata gttagacctt gtttttttat aagctaacta tcgaaaactg
    23341 gtcatctata aatcttagta ttccatcact caatcacaat tcataaagac tcgcaaactt
    23401 tcacaacttt taattctata ctttctgtag tgggtaaatc cacctcaaag attatagagt
    23461 ctttttaaac atatgtaaaa agttccatat gacgatctat aatgaaaagc gaccaaacta
    23521 tcatttcaga aagactcata taaaatcatc cgattatagt ataatttcat taggaatcta
    23581 aaaccttagc atcacggttt taaattatgt aaatgctggg gacgcaaaaa gcattcataa
    23641 tcatctcttt cattatacca gacaggttag aaggcatgtc aaagttatta ccataggcat
    23701 actcagtgcc cactactatg agattactat gctttttcta caggctaaaa ttatcctcga
    23761 ttgttttcat atcccccaac gtcttagaca agctataact cgctttcgta tccgaatcat
    23821 aaatacttct gctataaaac ctatcgcgta tagaactctc aaactttact gaaaactcat
    23881 acagcatgat tcacggaagc tcatcaataa taaatagctt tattgcccaa tttttcgtac
    23941 gcccataact aacatctaga aaagaaaagc tcttactcac aagatctctg aatttcaata
    24001 attattccta actctatcaa ctcttgctct tcccattttt cagacaattt ttaaaatttt
    24061 tctaaaagaa aagaaaacaa gattagcaat atacttaaac tcaactactc taaggccaaa
    24121 ttagaaacag tcaacaacct tatcaaagcc atcaagttaa acgttttact cctctacagt
    24181 agtcaaagag cctatcattt tagttatcga aataatgaac gatttaaata ttctatttag
    24241 ttggttttga agattacaaa aaaaagacga taaccgtctt ctttcccctt tatttataat
    24301 tcatccttta atatgtttca tttaacatat taaccaaaat atctttacaa aacggagaat
    24361 aagggattcg aacccttgcg ccagttaccc gacctaacga tttagcaaac cgtcctcttc
    24421 agcctcttga gtaattctcc aaatata
//
LOCUS       DATTYN010000032        24279 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.32, whole genome shotgun sequence.
ACCESSION   DATTYN010000032 DATTYN010000000
VERSION     DATTYN010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24279
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.32"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..456
                     /locus_tag="VB649_001498"
     CDS             <1..456
                     /locus_tag="VB649_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEP1670441.1"
                     /translation="AWQQRELVIACGKKHGFNNAYPLYFTKKSSPQVLKANMKIVGAV
                     EEATVLYRDKLPKFNNGGAMILNHAPWEKDSSYPVIHPTQKPIPVLKRLIEIFTDPDD
                     VVIDPVAGSGSTIRAAIEMNRNAYGFEIKKDFYKRAKEEMLSTFQTSLF"
     gene            547..840
                     /locus_tag="VB649_001499"
     CDS             547..840
                     /locus_tag="VB649_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670442.1"
                     /translation="MNTNEKVIDTICHIRHCGDRYDMCQDMRSWVAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            complement(873..1094)
                     /locus_tag="VB649_001500"
     CDS             complement(873..1094)
                     /locus_tag="VB649_001500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670443.1"
                     /translation="MFPFLKISLYNYVTIIPRYAAEYLQKASRVSLTSIPARRPTEPL
                     QALERLRGNLIAQLTDINVGQTRLLSACV"
     gene            1296..1733
                     /locus_tag="VB649_001501"
     CDS             1296..1733
                     /locus_tag="VB649_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEP1670444.1"
                     /translation="MGNIPTTKANNFLEELKTIPHLIETLERDANLMSRSLVKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            1895..3061
                     /locus_tag="VB649_001502"
     CDS             1895..3061
                     /locus_tag="VB649_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEP1670445.1"
                     /translation="MEFVDKKLSEITPYKNNPRNNDEAVGPVAESIKEFGFKVPIVVD
                     KNGEIVNGHTRYKAAQKLGLETVPVIVADDLSEEQIKAFRLADNKVGEIAVWDLDLLN
                     EELNDILDLDMSAFGFDVLDNLDDLIEDEKDLDDFTETVPDEPKSKLGDIYQLGSHKL
                     MCGDSTNGADVKKLMNGELADLLLTDPPYNVAYEGKTKDSLTIKNDSMDNDSFRQFLV
                     NAFSSANEVMKPGAVFYIWHADSEGYNFRGACFDIGWTVRQCLIWNKNSMVLGRQDYH
                     WKHEPCLYGWKDGAGHLWASDRKQTTVIDYEKPQRNGVHPTMKPVGLFDYQIKNNTKG
                     SDIVLDLFGGSGTTLIACESNGRHARLMEYDPKYVDVIIKRWEELTGESVIQLN"
     gene            3404..3880
                     /locus_tag="VB649_001503"
     CDS             3404..3880
                     /locus_tag="VB649_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670446.1"
                     /translation="MANEDNLIPNSKRTPSELREIAKKGGIASGKARREKANLRKAVE
                     LVLGSTVPSALLREQLEQLDISPTNQSAIALKLVENALKGDVRSAELLAKITTTEVKD
                     SLDRKEQRQRIKAAELATDEQRTRIELLKVKLDAEKGAKPDTSLMRALLDAVEGGD"
     gene            3963..5174
                     /locus_tag="VB649_001504"
     CDS             3963..5174
                     /locus_tag="VB649_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEP1670447.1"
                     /translation="MTPRSGKTTAGHFRYARYLIESEDENHLVTAYNQEQAYRLFIDG
                     DGTGLMHIFDGNCEIKHDERGDHLLITTPKGNKRVYYKGGGKVNSVGAITGMSLGSVV
                     FCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVFDVQNTRWTHWTMD
                     DNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDTEKNVLDALIGEPV
                     EMYFCADGGQSDATSMSCNIVTRVRDNGRISFRLNRVAHYYHSGADTGQVKAMSTYAL
                     ELKVFIDWCVKKYQMRYTEVFVDPACKSLREELHKLGVFTLGAPNNSKDVSSKAKGIE
                     VGIERGQNIISDGAFYLVNHSEEEYDHYHFLKEIGLYSRDDNGKPIDKDNHAMDEFRY
                     SVNVFVHRYYN"
     gene            5188..6690
                     /locus_tag="VB649_001505"
     CDS             5188..6690
                     /locus_tag="VB649_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP1670448.1"
                     /translation="MGVIQKIKNLVTRSKYVMTTQSLTNITDHPKIAISKLEYDRITT
                     NLKYYKSDWDSVLYLNTDGETKKRDLNHLPIARTAAKKIASLVFNEQAEIKVDDDAAN
                     EFISETLKNDRFNKNFERYLESCLALGGLAMRPYVDGDKVRVAFVQAPVFLPLQSNTQ
                     DVSSAAVVIKSVKTINGKEVYYTLIEFHEWQSSDDYVISNELYRSDDKAKVGSRVPLS
                     EVYKDLKDEAKVTDVTRPIFTYLKTPGMNNKDINSPLGLSIFDNAKTTIDFINTTYDE
                     FMWEVKMGQRRVAVPESLTALTVRTADGDVVPRPRFESDQNVYIRMGGRDLDSSAIQD
                     LTTPIRADDYIKAINEGLSLFEMQIGVSAGLFSFDGKSMKTATEIVSENSDTYQMRNS
                     IVTLVEQSLKELVISIFEIAKAYDLYQSEVPSMDNISISLDDGVFTDRDAELDYWIKV
                     VNAGFGTREMAIQKVLNVTEEKAQEIAAEINTGIVDEINQQRTDTHLYGE"
     gene            6695..8188
                     /locus_tag="VB649_001506"
     CDS             6695..8188
                     /locus_tag="VB649_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HEP1670449.1"
                     /translation="MKKKPIKLNDEQLLLEASQLSDMYHQLTLDLFDQVIERIKARGS
                     ASLADNPYLWQANKLHDVGLLNADNIKLIAKYSGIAEAQLRYIIKNEGFKIYKNTSEQ
                     LEEALGRESGVNSTIQDDLSNYARQAIDDVHNLTNTTLPFSVIGAYQGIIQDAVAGVV
                     TGLKTPDQAINQTVIKWFKKGFYGFTDKAGRKWRADSYARTVINTTTWRVFNEAKEAP
                     AREFGIDTFYYSKKATAREMCAPLQHQIVTTGEAREEGGIKILALSDYGHGEPDGCLG
                     INCKHTKTPFVVGVNSKPELPEHLKNTTPAQAKANANAQAKQRAIERSIRKSKELLHV
                     AKQLGDKELIRQYQSDVRSKQDALNYLINNNAFLHRNQAREKRYNNPYTKTQSEVEVR
                     KEKAKLDKRRDVESAIIGIETSEGIPLKITKHLAERAVLRNIAPIDIVDSIKEPLKIA
                     PIKYDNLDRPSQKYIGKCVSTVINPIDGNIVTVHATSTRIRKKYGGN"
     gene            8188..8415
                     /locus_tag="VB649_001507"
     CDS             8188..8415
                     /locus_tag="VB649_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670450.1"
                     /translation="MKLKSILNDSQIDFVKNELPGLPVDIDVNSEKYDVFCEGIETYY
                     QTESFDEKYNITAKGKLAESIIDLLTDKGYW"
     gene            8502..8768
                     /locus_tag="VB649_001508"
     CDS             8502..8768
                     /locus_tag="VB649_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670451.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQVEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            8894..9508
                     /locus_tag="VB649_001509"
     CDS             8894..9508
                     /locus_tag="VB649_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670452.1"
                     /translation="MHMENVTNENVDQETTDLENNQQEDKAFTQDDLNRVGTKEHSKG
                     YNKAVKDLGFDDVESAKDALKAFQEWQESQRSESEKQTEILNAKDKELEEARANNKAL
                     NAKLAAMSLGVNAESIDDVIALSERLVTDETSIEDAIKTVLGKYPHFGQTKDKAPKIT
                     VAGNPSADNGQGSVSKEDFAKMSYQEKLDLKLKNKNLYDQLKGN"
     gene            9512..10330
                     /locus_tag="VB649_001510"
     CDS             9512..10330
                     /locus_tag="VB649_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEP1670453.1"
                     /translation="MAVGTTKMAQMLDPEVLADMIDAEVGKAIRFAPLAEVDTTLEGQ
                     PGTTLTVPKWDYIGDAEDVAEGEAIPMTQLGFKKTTMTIKKAGKGVEITDEAILSGYG
                     DPVGQAAKQIVEAIDHKVDADVLDALSKSTQTVEATATVDGVSKALDIFNDEDDAETV
                     IVMNPADASTLRLDAAKEWLGATEVGANRVVSGVYGEVLGVQIVRSRKCPKGTAYMVR
                     KGALRIMLKRNTMVETDRDITKAINQIVANKHYGVYLYKAEKAVKITLKDAAKK"
     gene            10384..10800
                     /locus_tag="VB649_001511"
     CDS             10384..10800
                     /locus_tag="VB649_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670454.1"
                     /translation="MEVVIIAFLTQKEFEDLGFDEVEDFEKMEKRASHAVNLYCRNRY
                     DYKDLKKEIALVQKAVKRAIAYQIAYLNDSGVMTAEDKQSFAGISLGRTSISYTVGHG
                     QGSQQKTLADRFNLCLDAENELLAVGLGYTGISYDR"
     gene            10790..11122
                     /locus_tag="VB649_001512"
     CDS             10790..11122
                     /locus_tag="VB649_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP1670455.1"
                     /translation="MIDKRLLIDELQVKLVKDKGDYGGFVYDEPFTLSPVRFDRNLAT
                     AGKDNARQETKPSVIFIYPKYCKTVADRSWVDAVVIDGDTEYTVDKVIPVYHPLTNKI
                     FCFEVEVI"
     gene            11122..11478
                     /locus_tag="VB649_001513"
     CDS             11122..11478
                     /locus_tag="VB649_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP1670456.1"
                     /translation="MAKVVVELGGIKRKVSPQALAKGKLIMNNQVMMSMNPYVPYRDG
                     ALRGSSRANSVGVTWSGPHARAQFYGGAYNKYKSFKFKKYTTPGTGKRWDKRALANAT
                     IVKDWEKSLLRGMGFK"
     gene            11475..11873
                     /locus_tag="VB649_001514"
     CDS             11475..11873
                     /locus_tag="VB649_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEP1670457.1"
                     /translation="MTNDFATVLRQFVEGLDLGIKPRLDYLTRQEDLAIYPMPGGKVN
                     NEYMDGTREISLPFEIAIKTKNQELASTVMWTINSALSNFDLKLPSLNHSYTFISLDV
                     EKPFLNDLSDQGFYIYVLDITAHLEIEGNN"
     gene            11873..12358
                     /locus_tag="VB649_001515"
     CDS             11873..12358
                     /locus_tag="VB649_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP1670458.1"
                     /translation="MRQKNALRGHFIAPYVKGEEKTEVTKEKLLELARWIKDISDDTD
                     ERTEDEAYYDGDGTEETTVVGVKGAYTFEGTYDPEDKAQAHIASLKYKLGDERKVWHL
                     IVSADGKTQWLGVATVTEIIAGSGAAADFEAFGCKITYNSLPKESKEIIPKKNELSVA
                     M"
     gene            12397..12831
                     /locus_tag="VB649_001516"
     CDS             12397..12831
                     /locus_tag="VB649_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670459.1"
                     /translation="MSGIVVDLKRTGFPVKIGQVELWFDTSQERLIEFFDIETEVNRR
                     LNEYEKQVIEANLDNEIEDKGVTKDVAQSALDLEAKYLEINYDLLFGEGTFAQLYAEY
                     PDKEALENTLEIVCREIEVKLKELAIEREKIVKQKTKKYKKE"
     gene            12835..13416
                     /locus_tag="VB649_001517"
     CDS             12835..13416
                     /locus_tag="VB649_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage Gp15 family protein"
                     /protein_id="HEP1670460.1"
                     /translation="MKLNDPLVESFEFRGEIYPIDLSFNKVLDVFDVIDDDFLNEAEK
                     CFLCLDILLDRTDLPFTYAVDLWVYIKTNFIDAERPEKPQLDIKGNPMPVVKEKEDNK
                     KVIDLSLDAEFIYASFRQAYQINLLKEQNRLSWIEFKALLNALPDDTVMQRIIAIRQW
                     EDDGEGSKKYRDNMRKLKAKYSLDEREEEDDGS"
     gene            13406..16666
                     /locus_tag="VB649_001518"
     CDS             13406..16666
                     /locus_tag="VB649_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015967413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEP1670461.1"
                     /translation="MAADGKVTILVDVDGKQVKVLNSELDKVAKHGDKGSSSLKKFAV
                     GAGVFKLASAAVDLVSQSLGKAITRFDTLEKYPRVMKAMGHSAEYVARSTDKLANGID
                     GLPTTLDEVVGTAQRLTSITKDINKSTNLTLALNNAFLASGASSEAASRGLEQYAQML
                     SAGKVDMQAWKTLQETMPYALQQTAEAFGFAGASAQKDFYEALKNGQITFDQFSNKLI
                     ELNDGVGGFAELAKENSKGIETSFNNIKNAIAKGVANSIKALDDLSKAATGKGIADHF
                     DSLKVVINASFSAINASIKASTPLFKLLFSVIGAGISVVKALSPALVGVASGLAAMRA
                     VNETITMIKALNRAWVMASASMSIGATTIKTVTAVQAVSTTMTKADMVARLSQLGVLK
                     ASTVIYGVMTGAISLSTAATIASTAAVTALKAALVALTGPVGWVVGAIGALVAVGVSL
                     WSWLTKESDETKKLKKEQEGLVESNKQLRDSVREGVQERKKGLESVKESTAAHQKLAD
                     EIIKLAAKENKTAGEKQNLKNKIDQLNGSIDGLNLAYDKNSNSLSHNADQIKSRISAM
                     EAESTWQTAQQNLLNIEQKRSEVSKKLAENAELRKKWNEEANVSDSVRKEKIAELTEE
                     EGKLKNMQTQLQEEYNKTSATQQAAADAMAAAEESGSARQVIAYENMSEAQRTAIDNM
                     RTKYSELLETTTSIFDAIEQKTALSVEQMNANLEKNRAATEQWATNLEILAQRGVDQG
                     ILEQLRRMGPEGATQTQVFVDATDAELAPLQENFRAATETAKNAMGSVLDSAGVEMPE
                     KVKGMVTNVSTGLQAELQAANFAQLGQEIPNGVSQGISQGAGKASDASVKMGQEVKRS
                     FQGELGIHSPSRVFTEYGGHITDGLSNGVTNGTSKVMQTMQSLAQQMSQKGQQIVNDM
                     RSKSNQITDAFSTMSGPMHSHGVNAMQGLANGIYAGSGAALAAAQSIAARITATIQSA
                     LDIHSPSRVMRDEVGRFIPQGIAVGIDADRKVIDSSMQKLKESMTINATPEIASGFGG
                     GVAGIANQTTNNSNNSFTLNVKVDESDDNSREKYQRLFREFSWYIQQQQGRLGDVK"
     gene            16663..17379
                     /locus_tag="VB649_001519"
     CDS             16663..17379
                     /locus_tag="VB649_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEP1670462.1"
                     /translation="MTAFIKFDGKKSSDFDLRIINDVEHDSSFYDVDQVKVPGRDGVV
                     LKDNKRLEAIERSYPLRLYSKRRLTEVETDISNWLNVKGWKDLELSWEPDYIYKATHI
                     TPFSIKEVLRNFGRLKINFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKG
                     TGNGILTINDFETGLENVQSELVIDMERHLVYKDVLSAWDNIVRTERHRMPLFDVGQN
                     KISWTGSFTITAVPNWGVKV"
     gene            17376..19523
                     /locus_tag="VB649_001520"
     CDS             17376..19523
                     /locus_tag="VB649_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP1670463.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGVFASVFKEEMKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVNGASVGAESALEIWKKNLVGDDKFDVKSDILTLGSFNWEIDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEETPGKPHVGEHKQPEEQLVTLPEFILDGQYLSLYAQRRIQMVDLSSHFN
                     DDKNKKEPTIEEIRKLAQKYLKDNNVGAPKVSIEVDYIDLSQTLDYQDFRVMEEVELC
                     DIVPLYYPKFGITTESEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVSERINAL
                     ENNQKVITNNQKQFELNLPKYLNDINGNRVWYEKPDDNIEHKIGDYWFEKNGKYQRTW
                     IWDGNRWVKVLDTEDLNPNQRAFDEAMAEIEKAKKAQEEINQRTDKELEEFRATLKNL
                     ALPEEAIKKIKEAIKVDDIPSIKQSFDDLKNKVSETSETSRLNAEILGNNGKTRYNKN
                     LLVGDPNRVKTYDQDYIEVEANDGGFKRGETYTISFSQTCEPLNKVTITLTQANNKGL
                     KLVLTPTKAKMAPQTFDLTKDKEVINVYPLSYKGVLTGDWYKSKQIDLTASEAQILAL
                     EMAYKEVVDGKNADLVLDWAENPDIIFDGNGGI"
     gene            19523..20635
                     /locus_tag="VB649_001521"
     CDS             19523..20635
                     /locus_tag="VB649_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEP1670464.1"
                     /translation="MSKEVASARIQHRGMTTQGWESSPDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPTGERGPIGPTGPIGKTGTTDYNQLQNKPNLDAFAQKK
                     ETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKPSSS
                     VGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYSGKTNAVNI
                     AMRQPSTPNFSSALNITSGNENGSAMQLRGSEKALGTLKITHENPNVEANYDENAAAL
                     SIDIVKKQKGGKGTAAQGIYINSTSGTAGKMLRIRNENKDKFYVNPDGGFWSCANSTV
                     TGNLTVKDPTSEKHAATKKYVDEKIAELKKLIQKTD"
     gene            20645..22660
                     /locus_tag="VB649_001522"
     CDS             20645..22660
                     /locus_tag="VB649_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEP1670465.1"
                     /translation="MSRDPTLTLDESNLTIGSDGRAYYTFTADDNTKSVKIANDKCIG
                     TTRFNQLMIERGDKPTNYVAPVVVEGTGNPTGLFKDLKELNLELTDTANSQLWAKIKL
                     NNHGMLQTYFDTTIKNEILTTAQGIRETISDTKRGLRSEFLKTVQGQRIQLESLLEQK
                     TAQLGLTVDGLKLDLNKANKQTASLQASINGLRQDYQDADRRLSASYQSGINGLKAQL
                     ANDKIGLQAEIQATAQGLSQKYDNELRQLSAKITTTSSGTTEAYESKLAGLRAEFTRS
                     NQGTRTELESQISGLRAVQQTTASQISQEIRNREGAVSRVQQGLDSYQRRLQSAEGNY
                     NSLRETVAGYERRISNQDNTISSNFTQLKTLIDQSVTLEKVQSLLRQSGDSIMLAIKD
                     KLPKSKMSGNEIISAINLNSHGVQIAGKNITLDGNTTVNGAFTTKIANAIKIKADQII
                     AGVIDAAKIRVINLNASSIVGLDANFIKAKIGYAIVDMLEGKVIKARNGAMLIDLSSA
                     KMDFNSNATINFNSRDNALVRRDDTHTAFVHFSNATPKGYTGSALYASIGITSSGDGV
                     NSASSGRFAGLRSFRYATGYNHTAAVDQTEIYGDNVLIADDFNINRGFKFRPDKMTKM
                     IDMNDLYAAVVALGRCWKHLANVGWNTVHGNFVSAVNGELNNYITKI"
     gene            22672..23103
                     /locus_tag="VB649_001523"
     CDS             22672..23103
                     /locus_tag="VB649_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEP1670466.1"
                     /translation="MQLTIKNKDLNTLYCVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPTKLDEFSGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDSILEQFEESKKGE"
     gene            23106..23717
                     /locus_tag="VB649_001524"
     CDS             23106..23717
                     /locus_tag="VB649_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEP1670467.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQDLNS
                     TNDTEIIKAALEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQKMINLQTIHMLTSGGKIDPDIYKGLLELIEPAKQGEYQAYDVFTVVDESHEEQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            23728..24024
                     /locus_tag="VB649_001525"
     CDS             23728..24024
                     /locus_tag="VB649_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670468.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANEFAMAQLKD
                     SIKELAYELKNLDRDREITKKIIDRHEERLGRVEDEVIINKERIVTLFKKGEEK"
     gene            24021..24206
                     /locus_tag="VB649_001526"
     CDS             24021..24206
                     /locus_tag="VB649_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670469.1"
                     /translation="MNKWFKKVAIKTIKTMAQTAVGLIGSSMLITDINWPTMLSAVLL
                     SGLTCVLMNVSQIKEEE"
BASE COUNT         8216 a         4324 c         5513 g         6226 t
ORIGIN      
        1 gcttggcagc agcgagagct ggtcattgca tgcggtaaaa aacacggttt caataatgcc
       61 tatccactat attttacaaa gaaatcaagc cctcaagtac taaaagctaa tatgaaaatt
      121 gttggtgctg tcgaggaggc aacggtttta tacagagata agttaccaaa attcaataac
      181 ggtggagcta tgatccttaa tcatgcaccg tgggaaaagg atagctctta tccagttatc
      241 cacccaacac agaaaccaat cccagtttta aaaagattaa ttgagatttt cacagatcct
      301 gatgatgtgg ttattgatcc tgttgctgga agcggatcaa caattcgtgc agcaatcgaa
      361 atgaatagaa atgcttatgg atttgaaata aaaaaagatt tttataagag agcgaaggaa
      421 gaaatgctta gtacgtttca aaccagtctt ttttgaaaga gaaattgtag atgtagatct
      481 gttaatagag cttgcagaag ataatccgtt ttggatgagt gcattaaatt ttaagcgagg
      541 tacaaaatga acactaacga aaaagtaatc gatactatat gtcacatcag acattgcggt
      601 gacagatacg atatgtgcca agacatgcgg tcgtgggtag ctgagagaaa tggattaatc
      661 caggacttac tcaaagcaaa aaaacaaatt gatcgcaatc gtatcgctaa acgtctggat
      721 cgtgcgcaga aaaacatcag tgacattatc acaaaagtga caggcgactt atggcaaggc
      781 agtgatcaag tcattgctga gcagtgtttt ttaaaagtat tagaggagat gcaaaaatga
      841 acattgaaga agcgaaaaga gcgataagag aactagacgc aagcgctcaa gagcctagtc
      901 tgaccaacat tgatgtcggt cagttgagca attaaattcc cacgcaagcg ctcaagagcc
      961 tgcaatggct ctgtgggtct acgagctgga atactcgtta aacttaccct agaagctttc
     1021 tgtaagtatt cagctgcgta gcgtgggata atcgttacgt agttatagag cgaaattttt
     1081 agaaagggaa acattctcct tttttcataa aaatctaaag tctgttatcg ctcacagatg
     1141 attatacaag gcgtcgctaa tgctttaaca cgacatcgta cgcctgtgtc aaaaaacaaa
     1201 ggaaagagag gacttttctc cacaaaaaaa gacgtccatg cgaacgcctc catgattaaa
     1261 tacccaacaa tattatatca tgaatggaga gttagatggg caacattccg acaacaaaag
     1321 ctaataattt tttggaagaa ttaaagacta tcccacatct catagagacc cttgaaagag
     1381 acgctaacct aatgagtcgg tcgcttgtta agtctcctca gtggtctgat atgcgagtgt
     1441 ctggtggggt taaacaatca caggaagaca aaaacataaa gatgctgcat atggttagct
     1501 attatagtga tcagattgag cgtttaaaag accgtcgaca agaaatggct aatttgattg
     1561 tgcaaagcat gggcatttgt gagagtcacg ttttactcac gacttatctt gactgtgatg
     1621 gagactatga gagagccaga gaacgcttaa acataggaaa tcgtaataaa tactttatgt
     1681 ttgttaggcg aggaaaggaa agtctggaat tgatactaaa aaatactaat tagatacaaa
     1741 ttgatactac ataatactaa tagctgtgtt aatattgtag tatagcaaaa tagcaagaag
     1801 agataacctt ttaaccaatt ggctatttat ctatggttaa ccaattagtc atcacattgt
     1861 ggtgactttt tattatgtaa aaaaggaata aaacatggag tttgtggaca aaaaattaag
     1921 tgaaataaca ccttataaaa ataaccctag aaacaatgat gaggctgttg gaccagttgc
     1981 tgaatctatt aaagagtttg gttttaaagt gcctattgtc gttgataaaa acggcgaaat
     2041 cgtaaacggc cacactcgtt ataaagcagc ccaaaaatta gggctagaaa cagttcctgt
     2101 tattgtcgca gatgacttat ctgaagagca aattaaagcg ttcagacttg ctgacaataa
     2161 agttggtgag attgcggttt gggatttaga tttgttaaac gaagaattaa acgacatttt
     2221 agacctcgat atgtctgctt ttggatttga cgttttagat aatttagatg atttaatcga
     2281 agatgaaaaa gatttagacg attttacaga gactgtgcca gatgagccaa agtcaaaact
     2341 tggtgacatt tatcaacttg gtagtcacaa gttgatgtgc ggcgacagta caaatggagc
     2401 cgatgttaaa aaacttatga atggagaatt agctgattta ctacttacag acccaccata
     2461 caacgtggct tatgagggta aaacaaaaga tagtttaact ataaaaaacg acagtatgga
     2521 taatgacagt tttagacagt tcttggttaa tgcttttagt tctgcaaatg aagttatgaa
     2581 gccaggcgct gttttttata tttggcatgc tgattcagaa ggctataatt ttagaggtgc
     2641 ttgttttgat atcggttgga cagtacgtca atgcttaatt tggaataaaa actcaatggt
     2701 tctcggtcgc caagattatc attggaagca cgaaccttgt ctttatggct ggaaagatgg
     2761 cgctggtcac ttgtgggctt cagacagaaa gcaaacaaca gttattgatt atgagaaacc
     2821 tcaacgaaat ggcgttcatc caacaatgaa acctgtcgga ctttttgatt accaaatcaa
     2881 aaacaacaca aagggaagcg acattgtcct tgatttgttt ggtggctctg ggacaacgtt
     2941 aattgcttgt gagtcaaatg gtcgtcacgc tagattaatg gaatatgacc caaaatatgt
     3001 agatgtcatt ataaaacgct gggaagaatt aactggagaa agtgttatac aactaaacta
     3061 aaaacccctt aaaaccgttg acttaacagt gtttcagagc tatcatgtga tcacaaagac
     3121 aaagaggtaa ataacatgct agtaacaaaa gtaattcaca aaatctaaaa tattgaacca
     3181 agcgaaaaag attcggcctt aaaatataga tacgccaacg aacttgagta tctcgtttac
     3241 aatctgtttt atagcgcaat taaagaaata actgcaaaag atatcaaaaa taactttttt
     3301 tatcaagatg atcaagcctt tattattaat tggctaggac tataaaataa ttttaaaagg
     3361 gcgaaagcct tttttttata tttaaaagta aggaagtgag gcgatggcaa atgaagataa
     3421 tttgatacca aactccaaac gaaccccgag cgaactccga gaaattgcaa aaaaaggagg
     3481 catagcttcc ggcaaagcta ggagggaaaa agcgaatttg agaaaagctg tggagctggt
     3541 gttaggatca actgtaccaa gcgccttgct tcgagaacaa ttagaacaat tggatatttc
     3601 ccccacaaat caatcagcta ttgcactcaa gcttgtggaa aatgctttaa agggtgatgt
     3661 tagatctgca gagctattag ctaaaattac aactaccgag gtcaaagata gcctggatag
     3721 aaaagaacaa agacagcgaa ttaaggccgc ggagctcgcc acagacgagc aacgaacgcg
     3781 catcgagctg cttaaagtca aacttgacgc agagaagggc gctaagcctg atactagctt
     3841 aatgagagcc ttgttagatg ctgtggaagg aggtgattag ccttggagat tatcttttca
     3901 aataaacaaa aagacgtcat tagacgccct tttaactacg aattagaggt caacgagggc
     3961 acttgacccc tcgtagcgga aagaccacag ctgggcattt tcgttatgct aggtatctga
     4021 ttgagtcaga agatgaaaat caccttgtga ctgcttataa tcaagaacaa gcttatcgtt
     4081 tgtttatcga cggcgatggc acgggtttga tgcatatatt tgacggtaac tgcgaaataa
     4141 aacacgacga gcgtggagat cacttgttaa tcacgacacc aaaaggcaat aagcgcgttt
     4201 attataaagg cggcggtaaa gttaacagtg ttggtgctat tacaggtatg tctttaggat
     4261 cagtagtatt ctgcgagatt aacttactgc acatggattt tatccaggag tgttttaggc
     4321 gtacttgggc ggctaagcta cgttatcatc tagcagattt aaatccccca gcacctcaac
     4381 atccagtaat taaagatgtc tttgatgttc agaacacgag gtggactcat tggaccatgg
     4441 atgataaccc aatactaacc gcagagcgta aacaaaacat tatcaacagt cttaaaaaaa
     4501 atccatatct atacaaacga gatgtacttg gacagcgggt catgcctcag ggagttattt
     4561 atggcctttt tgacacggaa aaaaatgttt tggatgcttt gattggcgaa ccagtagaga
     4621 tgtatttctg tgcagatgga ggtcaatcag atgccacctc tatgtcttgt aatatcgtaa
     4681 caagagttag agataacggt aggataagct tcagacttaa tcgtgtagct cactactacc
     4741 acagcggagc tgacactggc caagtaaaag ctatgtcaac ctacgcttta gagttaaaag
     4801 tttttataga ctggtgcgtt aaaaagtatc agatgcgcta tacagaggta tttgtggatc
     4861 ctgcctgtaa atctttgaga gaggagctgc ataagttagg agtatttact ctgggagctc
     4921 cgaacaattc taaagatgta tctagcaaag caaaaggtat tgaggtcggt atcgaacgcg
     4981 gccaaaacat tatctcagat ggcgcttttt atcttgttaa tcatagcgaa gaagagtatg
     5041 accactacca ctttttaaaa gagatagggc tgtacagtcg tgacgacaat ggcaaaccta
     5101 ttgataaaga taaccatgcc atggacgagt ttagatacag cgtcaacgtg tttgtgcatc
     5161 ggtattacaa ctaaaggagt tgcttaaatg ggagtaatcc aaaaaataaa aaatcttgtt
     5221 acaaggagta aatacgtgat gacaacgcag agtcttacaa atataactga tcatcctaaa
     5281 atagctatca gtaagctaga gtacgatcgt ataacaacca atctaaagta ttataagagc
     5341 gattgggata gtgttttata cttaaacacg gacggcgaga ctaaaaaaag agatcttaac
     5401 catctaccaa ttgcacggac agctgctaaa aagattgcca gtctagtctt taacgagcag
     5461 gcagagatta aggttgatga tgatgcggct aacgaattta ttagtgagac actaaaaaac
     5521 gacaggttta ataaaaactt cgagcggtat ctggagagtt gtttagcgtt aggcggatta
     5581 gctatgaggc cttatgtgga tggtgataaa gttagggtag catttgttca agcgcctgtt
     5641 tttttgccac tgcagagtaa tacgcaagac gtttcgagtg ccgccgtcgt cattaagtcc
     5701 gttaagacaa tcaacggcaa agaggtctac tataccttga tagagttcca tgagtggcag
     5761 agctctgatg attatgttat ctcaaatgag ttatatcgct cggatgataa agccaaagta
     5821 ggtagccgag tgccgttatc tgaggtatac aaggacttaa aagacgaggc aaaagttaca
     5881 gatgtgacta ggcctatctt tacttatctc aagacccctg gaatgaataa caaggatatt
     5941 aatagcccac ttgggctatc tatctttgat aacgccaaga caacgattga ctttatcaat
     6001 acgacctatg acgaatttat gtgggaagtt aagatgggtc aacgtcgagt tgctgtgcca
     6061 gagagtttga ccgctttaac tgttcgtacc gctgatggcg atgttgttcc aaggcctcgg
     6121 ttcgagtctg atcaaaacgt ttatatccgt atgggcggca gggatttaga ctcaagcgca
     6181 atacaggacc taacaacccc tattagagct gatgactata tcaaggctat caacgagggc
     6241 ttgtcgttgt ttgaaatgca aataggcgta tccgctgggt tatttagttt tgatggcaaa
     6301 agcatgaaga ctgcaacaga aatcgtctct gaaaactcag acacctacca aatgcgtaac
     6361 agtattgtta ctttagtaga gcaatcgcta aaagagttag ttatctctat ttttgagatt
     6421 gctaaagctt atgatttgta ccaaagcgaa gttccaagca tggataacat cagcataagt
     6481 cttgatgacg gtgtttttac agatcgagac gctgagttag actactggat aaaagttgtt
     6541 aatgctggct ttggcactcg tgagatggcc atccaaaaag tgctaaacgt gacagaggaa
     6601 aaagcccaag aaatagctgc agaaattaat actggaatcg ttgacgaaat caatcaacag
     6661 cgcactgata cacatttata cggagagtga ttagatgaaa aagaagccta ttaagttaaa
     6721 tgacgaacag cttcttttgg aagctagtca gttatctgat atgtatcatc agctgactct
     6781 tgatttattt gatcaagtga ttgagaggat aaaagccaga ggctcagcga gcttagccga
     6841 taatccttat ctttggcaag ctaataagtt acatgacgtt ggactgctta atgcagataa
     6901 catcaagctt attgcaaagt attctggcat tgcggaagct caacttcgct atattatcaa
     6961 gaatgaagga tttaaaattt ataaaaacac gtctgagcag ctagaagagg ctctaggtag
     7021 agagtctggg gtaaacagta ctatccaaga cgacctatct aactatgcta gacaagctat
     7081 tgatgatgtg cataatttga ctaacaccac cttgccattt agtgttatag gagcttatca
     7141 agggataatc caagacgctg ttgctggtgt ggtgacaggc ttaaaaacgc ctgaccaagc
     7201 tatcaatcaa actgtgatta aatggtttaa aaaggggttt tatggtttta cagataaagc
     7261 tgggagaaag tggagagcag actcttatgc tcgtaccgtt atcaatacta cgacttggcg
     7321 agtctttaac gaagccaaag aagcccctgc tagggagttt ggcattgata ccttctatta
     7381 ctcaaaaaaa gctacagcta gagagatgtg tgcacctttg caacatcaaa ttgtcactac
     7441 tggcgaagcg agagaagaag gagggataaa aatcttagct ttatctgatt acgggcatgg
     7501 tgagcctgat ggatgcttgg gaatcaactg caagcacact aaaacgccgt ttgtcgtcgg
     7561 tgtgaatagt aagccagaat tgccagagca tctaaaaaat accactcctg cacaagctaa
     7621 agctaatgcg aatgcgcaag ctaagcaaag ggcaatcgag agatcaatac gtaagagtaa
     7681 agagctactg cacgttgcga agcaattggg tgataaagag ttgattaggc aatatcaatc
     7741 ggatgttaga agtaaacaag atgcactcaa ttatctgata aacaacaatg cctttttaca
     7801 tcgcaatcaa gccagagaaa agcgttacaa taatccttat accaaaactc aaagtgaagt
     7861 cgaagttaga aaagaaaaag ctaaattaga taaacgtagg gatgttgaaa gtgctataat
     7921 aggaatagaa actagtgaag ggataccgct aaaaataaca aagcatttag ccgaaagggc
     7981 ggtgctgaga aatatagcac ctattgatat tgtcgattct ataaaagaac cgttgaagat
     8041 agctcctatt aagtacgata accttgatag accttcccag aaatacattg gtaagtgtgt
     8101 ctcgacagta ataaacccga tagacggaaa tattgttaca gttcatgcta ctagcacgag
     8161 aatccgcaaa aaatatggag gaaattgatg aaattaaaaa gtattttaaa tgatagtcaa
     8221 atcgattttg tcaaaaatga acttccggga ttacctgtgg atatagatgt taattccgaa
     8281 aagtatgatg ttttttgtga aggtatagag acttactacc agacagaaag ctttgatgaa
     8341 aagtacaata taacagctaa aggtaaacta gctgagagta ttattgattt actgactgat
     8401 aaaggttatt ggtgactagt acaccaaact acgacttatt aaatctagag catttagcta
     8461 aaagctaggt gcttttttgt acttaaaaaa taggagggaa catgaataaa cgcattaaga
     8521 aaaaacgtaa actagaaaca gcagttgtga tgcttgttgc agaaaatgcc atgcaggttg
     8581 aagcaattaa aaatcaaaac aaacaaatca tggagctaaa atcaatcgtt caacgaaacg
     8641 ctctggcaac aaacgaagag ttagcgactg ttaaagctgc tactttagat aaccaatcag
     8701 ttatcaaggc aattggtgac acggttgact atattaagaa aaactacaaa cggaagtggg
     8761 ggaaataaag tttaaccgtg tcgaattcga cccctttaga aatcaaagtc gtagcaatac
     8821 ggctttttat tatgccttta tccgcaggcg ttaaagaacg gaaatcagcg acctatcgca
     8881 tttataggag ggaatgcaca tggaaaatgt gacaaacgaa aatgtcgacc aagagactac
     8941 tgacttggaa aataatcaac aagaagataa agcatttaca caagatgatc tcaaccgagt
     9001 gggaactaaa gagcattcta aaggctataa caaagcagtt aaagacttgg gttttgatga
     9061 tgtagagtct gccaaggatg cactaaaagc cttccaagag tggcaagagt cacaaagaag
     9121 cgagtcagaa aaacaaacag aaatcttgaa tgctaaagac aaagagcttg aggaagctcg
     9181 ggcaaacaat aaggctctta atgcaaagct agcagcaatg tctttaggtg tgaacgctga
     9241 atctattgat gatgtgattg cactatctga gcgtcttgtc actgacgaga caagcataga
     9301 ggatgcaatc aaaacggttt tgggtaagta tcctcacttt ggccaaacaa aggataaagc
     9361 tcccaaaatc acagtggcag gcaacccgtc tgctgataac ggacaaggtt cggtgtctaa
     9421 ggaagacttt gcaaagatgt cttaccaaga aaaactggac ctaaaactaa aaaataagaa
     9481 tctttatgac caattgaaag gaaattaaaa aatggcagta ggaacaacta aaatggcaca
     9541 aatgctagac cctgaggttc tagcggatat gattgacgca gaggtaggga aagcgattcg
     9601 ctttgctcct cttgctgaag tagatacaac tttagaagga caaccaggta caactttaac
     9661 agtgcctaaa tgggattaca ttggtgacgc agaagatgtt gccgagggtg aagctatccc
     9721 aatgactcaa cttggcttca aaaagactac tatgaccatt aaaaaagccg gaaaaggtgt
     9781 agaaatcact gacgaagcta tcttatctgg gtatggggat cctgtaggtc aggcagcaaa
     9841 gcaaatcgtt gaggctattg accacaaagt cgatgcagac gtgcttgatg cgttaagtaa
     9901 atcgactcaa actgtggaag ctactgctac ggttgatggt gtatctaaag cgctagatat
     9961 ttttaatgac gaagatgacg cagagacagt cattgtcatg aatccggcgg atgcctctac
    10021 cctacgttta gatgccgcga aggagtggtt aggtgctacc gaggttggag caaatcgtgt
    10081 tgtctctggt gtttatggtg aagttttagg ggtacaaatt gtgcgttctc gcaaatgccc
    10141 taaaggaact gcctacatgg ttcgcaaagg tgcactacgt atcatgctta aacgtaacac
    10201 aatggttgaa acagaccgag atatcacaaa agcgattaat caaatcgtag ctaataagca
    10261 ttatggtgtt tatctttata aggcagaaaa agccgtcaaa attacactta aagatgccgc
    10321 aaaaaagtag ctaaggctaa ggctgccaag agagaggaag atgacgctct cgagtcttag
    10381 ccgatggagg tggttattat cgctttttta acgcaaaaag aatttgaaga tttgggtttt
    10441 gacgaggtag aagattttga aaaaatggaa aaacgtgcta gccacgctgt caatctttac
    10501 tgtcgtaatc gctatgatta caaagattta aaaaaagaaa tagccctagt gcaaaaggct
    10561 gtaaagcggg caatcgctta tcagatagca tatttaaatg actcaggagt aatgacagca
    10621 gaggataaac aatcctttgc tggaatatct ctaggacgga caagtattag ctacactgtc
    10681 gggcatggcc aaggcagcca acaaaaaact ctggcagaca ggtttaatct ctgtctagat
    10741 gcagagaatg agttactagc tgttgggttg ggatatacgg gtattagcta tgatcgataa
    10801 aagactgctt attgacgaac tgcaggtaaa acttgtcaaa gataaaggtg attatggagg
    10861 gtttgtctat gacgaacctt ttacactctc tcccgttagg tttgaccgta atcttgcaac
    10921 cgcaggtaaa gataatgcaa ggcaagagac taagccgtcg gttatcttta tttatcctaa
    10981 atactgtaag acagtagccg ataggtcatg ggttgatgct gttgtcattg atggtgatac
    11041 tgagtacacc gttgataaag tgataccagt ctaccaccca ctaacaaaca aaattttttg
    11101 ttttgaagtg gaggttatct aatggctaag gtagtggtag agttgggagg catcaagcgt
    11161 aaagtatctc cgcaagcatt agctaaagga aagctcatca tgaacaacca agtcatgatg
    11221 tccatgaacc cttatgttcc ttacagagac ggagctttga gaggaagctc gagagctaac
    11281 agtgtaggtg taacgtggag cggaccacac gccagagccc agttttatgg tggtgcttac
    11341 aacaagtaca agtcctttaa atttaaaaag tacacaacac caggtacagg caaacgttgg
    11401 gataaacgtg cgttagctaa tgcaacaatt gtcaaggatt gggaaaaatc cttactgaga
    11461 ggaatgggat ttaaatgaca aatgactttg caactgtttt gaggcaattt gtcgaaggat
    11521 tagacttagg cataaagccc agacttgact atctaacaag acaagaagat ttagccattt
    11581 atccaatgcc aggtgggaag gtaaataacg agtacatgga cggtactcgt gagataagcc
    11641 tgccttttga gattgcaatc aaaactaaaa atcaggagtt agcaagcact gtgatgtgga
    11701 ctattaacag tgctttgtct aactttgact taaaattacc aagtcttaat cattcgtaca
    11761 catttattag ccttgatgtc gaaaagccgt ttttaaatga cttaagcgat caaggttttt
    11821 atatttatgt gctggatatt acagcacact tagaaataga agggaataac taatgagaca
    11881 aaagaacgcc ctacgtgggc attttatcgc accttatgta aaaggtgagg aaaagacaga
    11941 agttacaaaa gagaagcttt tggaattggc tagatggatt aaagacatct cagacgatac
    12001 cgacgaaagg acagaagatg aggcgtacta tgacggagat ggaacagaag aaacaaccgt
    12061 tgtaggagtt aagggcgcgt acactttcga agggacgtat gatccagaag acaaagctca
    12121 agctcacatt gcaagtctta agtataagct aggagatgag cgaaaagttt ggcatttgat
    12181 tgtatcggct gatgggaaaa cccagtggct aggggttgca acagtgacag aaattattgc
    12241 tggttctggt gctgccgccg attttgaagc ctttggttgc aagattactt ataactctct
    12301 gccaaaggaa agcaaggaaa ttatacctaa aaaaaatgaa ttgagcgtag cgatgtgaga
    12361 caagggtggg ctaaaccacc cttttaagga ggaattatgt ctggaattgt agttgaccta
    12421 aagcgcacag ggtttccggt caaaattggg caggtagagc tttggtttga tacaagccaa
    12481 gagcgattga ttgagttttt tgatattgag acagaagtaa atcgtcgcct caatgaatac
    12541 gaaaaacagg ttatcgaagc caacttagac aacgaaattg aagataaagg ggttacgaaa
    12601 gatgttgccc aaagtgcttt agatttggaa gctaaatact tagaaatcaa ttatgatcta
    12661 ctattcggag aaggtacatt tgcacagctc tacgcggagt atcccgacaa agaagcactc
    12721 gagaatactc tggaaattgt ttgcagggaa atcgaggtca aactcaaaga gttagctatc
    12781 gaaagagaaa aaatcgttaa gcagaaaacg aaaaagtaca aaaaggagta gcctatgaaa
    12841 ctaaacgatc cattagtaga gtcgtttgag tttagaggtg aaatctatcc tattgatttg
    12901 agctttaaca aggttttaga tgtctttgat gttattgatg atgatttttt aaacgaggcg
    12961 gaaaagtgtt ttttgtgcct tgatattttg ctagatagga cagatttacc ttttacttac
    13021 gcggtggatc tttgggttta tatcaaaacc aattttatcg atgcagaaag gcccgagaaa
    13081 cctcagctcg acatcaaagg gaatccaatg cctgtagtaa aagaaaaaga ggataacaaa
    13141 aaagtcattg atttgagttt agacgctgag tttatctatg cgagctttag gcaagcctac
    13201 caaatcaatc ttttaaaaga gcaaaacaga ttgtcttgga ttgaattcaa ggctctttta
    13261 aatgctcttc cagacgatac tgtcatgcag cgtatcatag ccattagaca gtgggaagat
    13321 gatggtgaag gcagtaaaaa atacagagat aacatgcgta agctaaaggc taagtacagt
    13381 ttagatgaaa gagaggagga ggacgatggc agctgatggt aaggtaacga tacttgttga
    13441 cgttgatggt aagcaggtaa aggtactcaa tagtgagtta gataaagttg ccaagcacgg
    13501 tgacaaaggc agctcctctc ttaaaaaatt tgcggttggt gcaggagtct ttaaattagc
    13561 ttcggctgca gttgatttgg ttagtcaatc tcttggcaag gctatcacaa gatttgacac
    13621 gcttgaaaaa tatccaaggg tcatgaaagc tatggggcat agcgctgagt atgttgctag
    13681 atcaactgat aagttagcga acggaattga tggactacca acaactttag acgaggttgt
    13741 cggaaccgct caacgtttga cctctattac taaggatatc aataaatcaa ctaatctcac
    13801 actagcatta aataatgcct ttttagcttc aggagcttca tcagaggctg caagccgagg
    13861 gctggagcag tatgcccaaa tgctatcagc tggtaaggtt gatatgcaag cttggaaaac
    13921 cctccaagaa acaatgcctt atgccttgca acaaactgcg gaagcttttg gatttgcagg
    13981 ggcatcagct caaaaggatt tttatgaggc attaaaaaac gggcaaataa catttgacca
    14041 attttctaat aagttgattg agttaaatga tggtgtcggc ggttttgcag aactagccaa
    14101 agaaaatagt aaagggattg aaacctcttt taacaacatc aagaacgcta ttgcaaaagg
    14161 tgtggccaac agcattaagg ctttggatga tttatctaag gctgcaacag gtaagggcat
    14221 agctgatcat tttgatagtt tgaaagttgt tatcaatgcc tcttttagcg ccatcaatgc
    14281 aagtattaaa gctagtacac cgctatttaa acttttgttt agtgttattg gtgctggaat
    14341 atcagtcgtc aaagctctgt cgcctgcctt agttggtgta gcatctggtc tagctgccat
    14401 gagggcagtt aatgagacta taacaatgat taaagcgcta aatagagctt gggttatggc
    14461 atctgcatca atgagtattg gagcaacaac cattaagact gtgactgcgg tacaagcggt
    14521 aagtaccacg atgactaaag cagatatggt tgcaagacta tctcagttag gtgtcttaaa
    14581 agccagtacc gtgatttatg gtgttatgac aggcgctatc agtttatcta ctgctgcaac
    14641 catagccagt actgctgcgg taactgcgtt aaaagcagca cttgtagcct taacaggtcc
    14701 cgttggttgg gtagttggag ctatcggtgc tttagttgct gtcggagtaa gcttatggtc
    14761 atggctaact aaagagtcag acgagaccaa aaagctgaaa aaagagcagg aggggctagt
    14821 cgaaagcaac aaacagctaa gagattctgt ccgtgagggc gtgcaagagc gtaagaaggg
    14881 ccttgagtcc gtcaaagaga gcactgcagc tcatcaaaaa ttagctgacg aaatcattaa
    14941 gttagccgcc aaagaaaaca aaactgcagg cgaaaaacaa aacttaaaaa ataagattga
    15001 tcagcttaat gggtctattg atggcttaaa cttggcctat gacaaaaact ccaattctct
    15061 ttctcacaat gcagatcaaa ttaagtcacg cattagtgcc atggaagcag aaagcacatg
    15121 gcaaacagca caacaaaacc tgttaaatat tgaacagaaa cgtagtgagg ttagtaaaaa
    15181 gctagctgaa aatgccgagc tacgtaaaaa gtggaatgaa gaagctaacg tctccgactc
    15241 tgtccgaaaa gaaaagattg ccgaactcac agaagaagag ggtaagctta aaaatatgca
    15301 gactcaattg caggaggagt ataacaagac atcagctact caacaagctg ctgcagacgc
    15361 tatggctgcc gctgaagaat caggatcagc aagacaggtt atagcgtacg aaaatatgtc
    15421 agaagctcaa cgaactgcca tagacaatat gcgcactaag tactctgaac ttttagagac
    15481 aacgacatct atttttgatg ctatcgaaca aaagactgct ctgtcagtgg agcaaatgaa
    15541 tgccaacctt gaaaaaaata gagctgctac tgaacaatgg gctacgaatt tggaaatttt
    15601 ggctcagcgt ggtgtggatc aaggtatttt ggagcaacta aggcggatgg gacctgaggg
    15661 ggcaacacag acacaggttt ttgtggatgc cacagatgcc gagctagcac ccttgcagga
    15721 aaactttaga gcagccacag aaactgctaa aaatgcaatg gggagcgttt tagactcagc
    15781 aggtgtggaa atgccagaga aagtcaaagg catggtcaca aatgtttcta cgggattaca
    15841 ggctgaactg caagctgcta actttgctca acttggccaa gaaatcccta atggggtttc
    15901 tcaaggtata agtcaagggg caggtaaagc aagtgacgca agtgtcaaaa tgggtcaaga
    15961 agttaaacgc tctttccaag gagagttggg tatccactcg ccatcgcgag tatttactga
    16021 gtacggtggc catattactg atggcttgag taatggtgtg acaaatggaa cgtcaaaagt
    16081 tatgcaaacc atgcagagct tggctcaaca gatgtctcaa aaaggacagc agattgttaa
    16141 tgacatgcgt agcaagtcga accaaatcac agatgctttt agcacgatga gtggtccaat
    16201 gcactctcat ggtgttaatg ccatgcaagg tttggccaat ggtatttatg cagggtcggg
    16261 ggcagcttta gcggcagctc aaagcattgc ggcacgtatc accgcaacaa ttcaaagtgc
    16321 cttagatatc cactcgccat ctcgtgttat gagggatgag gttggacgtt ttatccctca
    16381 gggtatcgct gtaggtattg atgcggatag aaaagtcatt gactcatcta tgcaaaagct
    16441 aaaagagtca atgacgatta atgcgacccc agaaatagcc tctggatttg gcggaggagt
    16501 tgcggggatt gctaatcaga ccacaaataa ctcaaataac agttttaccc ttaatgtcaa
    16561 ggttgatgaa tccgacgata atagccgcga gaaatatcaa cgcttattca gagaatttag
    16621 ctggtatatt caacaacaac aaggaaggtt aggtgatgtt aaatgacagc ttttatcaag
    16681 tttgatggta aaaaatcttc agattttgat ttgagaatta ttaatgacgt tgagcatgac
    16741 tcgtcctttt acgatgttga tcaagttaag gtacctggtc gtgatggtgt ggttttaaag
    16801 gacaataaaa ggcttgaggc tattgaacgg tcttaccctt tacgtctata tagcaaaaga
    16861 cgactcaccg aagtagaaac tgacataagc aattggctga atgtaaaagg ttggaaagac
    16921 ttagagttgt catgggagcc tgattatatc tataaagcaa cacatatcac cccttttagc
    16981 ataaaggagg ttttaaggaa tttcggcaga ctgaaaatca acttcttaat ccaccctatc
    17041 aaatatttaa aaacaggtaa gcaagaggtg cctctcgtta atggcggtac tctacaaaat
    17101 cccggcaatg ttcaagctaa acctatccta aaaatcaaag gcacaggcaa tggtatttta
    17161 accattaatg actttgagac aggacttgaa aatgtgcaga gcgagcttgt tatagatatg
    17221 gaaaggcacc tagtctataa agatgtccta tctgcttggg ataatatcgt aagaacagaa
    17281 cgccaccgca tgccgttatt tgacgttgga caaaataaaa tctcgtggac tggtagcttt
    17341 acaattaccg cagtgccaaa ctggggggtt aaagtatgat accagttttg tatgaggcta
    17401 aggaaaccaa gtttaggact tttggtctcg gtgagattgc ggatgcttat gaggttaaag
    17461 ccactcgtga gcgcaatggt aattactcac tgtacatcaa atatccgcta gatggtgtct
    17521 ttgcctcagt ttttaaagag gaaatgaaga ttaagtctga cgctggtcgt agaaccaaat
    17581 ggcagacttt tgagattaat cgggtactac gaaatagtaa agaccacatc gagatttttg
    17641 cgcgtcatat ctctatgcgc acacaggata ttgctttaaa accgtttgta aacggtgcga
    17701 gcgtaggagc cgaatcagct ttagaaatct ggaagaaaaa ccttgtcggt gatgataagt
    17761 ttgacgttaa aagcgacatc ttaacgcttg gtagctttaa ctgggaaatt gataaaatcg
    17821 gcaatgcccg tggtgctcta ggaggtgtcg ctggctctat cctagatgtc tacggtggtg
    17881 agtatgaatt tgacaatcgc accatcatct tacataagca gatgggtcgt aaagctccta
    17941 cggtgcttga gtatggccgt aatatcgtca gcgtagagga ggagcgattg ctagatggca
    18001 attacacctc tatctatcct tacgtaagat atacgccaca accaaaaccg caagaggaaa
    18061 cccctggtaa gccgcatgta ggcgagcata aacaacccga agaacagcta gtgacattgc
    18121 ctgaatttat cctagatggt cagtatctca gcttatatgc tcagcgcaga atccaaatgg
    18181 ttgatttatc aagtcatttt aacgatgaca aaaataaaaa agagccaacg atcgaagaaa
    18241 tccgaaagct ggctcagaaa taccttaagg ataataacgt tggtgcacca aaagtcagta
    18301 tcgaggttga ttatattgac ttgtcacaaa cgcttgacta tcaagatttt agagtcatgg
    18361 aagaggttga gctttgcgac attgtaccac tttattatcc aaagtttggc atcacaactg
    18421 agtctgaaaa agttgttgag attgtctatg acgtctatac agatagcaac catacaataa
    18481 aacttggcac gattggtcag tccatctcta aaagtttgac tggtggtgtt tccgaacgta
    18541 tcaatgcgtt ggaaaataat caaaaggtta ttactaacaa ccaaaaacag tttgaactca
    18601 atctgcctaa atacctcaat gacatcaatg gtaaccgtgt ctggtacgaa aaaccagatg
    18661 acaatattga gcacaagata ggtgattact ggtttgaaaa aaatgggaag tatcagcgca
    18721 catggatttg ggatggcaat cgatgggtta aagtactaga tacagaggat ttaaacccca
    18781 atcaacgagc ttttgatgag gcgatggcgg aaatcgaaaa agctaaaaaa gcgcaggaag
    18841 aaattaacca gcgtactgac aaagagctag aggaattccg agccaccctc aaaaacctag
    18901 cgttaccaga ggaagcgatt aaaaaaatca aagaggctat caaagttgat gacatcccat
    18961 caattaaaca aagctttgat gacctcaaaa acaaggtcag tgaaacgagc gagacatccc
    19021 gtctaaacgc cgaaatttta gggaataacg gtaagactcg ctacaacaaa aacctcttgg
    19081 ttggcgaccc taaccgtgta aaaacctatg accaagacta tatcgaggta gaagctaatg
    19141 atggcggctt taagcgtggc gagacctaca cgattagctt tagccagaca tgtgagccac
    19201 tcaataaagt gactatcacg ctaacacagg ctaataataa aggccttaag ttagtgctga
    19261 caccgaccaa agcaaaaatg gcgccacaga cctttgacct cactaaagat aaagaggtca
    19321 tcaacgttta tcctttgagc tataaaggcg ttttaacagg cgactggtat aaatctaagc
    19381 aaatagattt aaccgcgtca gaggcgcaaa ttttagctct ggagatggct tataaagagg
    19441 ttgtggatgg taaaaatgct gatttagttt tggattgggc ggaaaaccca gatattattt
    19501 ttgacggaaa cggaggtatt taatgtcaaa agaagttgca tcagcaagga tacagcatag
    19561 aggcatgacc acacaagggt gggaatcaag tcccgatatt ttaatggagc gagaaattgg
    19621 aattgacatg actacgggtt acccaaaagt tggcgatggt aaaaataagt tcaaggactt
    19681 aaaagacttg cgtggtccta tgggacctca aggtcctaca ggagaaagag gcccaattgg
    19741 cccaacaggt ccgattggca agactggaac gacagattat aatcaactcc aaaataaacc
    19801 aaatctagat gcgtttgcac aaaaaaaaga aactaatagt aaaatcacca aattagaatc
    19861 aagcaaagca gataaaagcg ctgtttactc aaaagcagag tcaaaaatag agctagacaa
    19921 aaaattgagt ttgacaggcg gcatagtgac aggacaacta cagtttaaac ctaataaaag
    19981 tggtattaaa ccctcatctt ccgtaggagg agcgattaac attgatatgt ctaaatcgga
    20041 aggtgctggt gttgttgtct attctaacaa tgataccagt gatgggccgt taatgagctt
    20101 gcggacgggt aaagagacct tcaataaatc ggcgcttttt gtcgattaca gcggtaagac
    20161 taatgccgtt aatattgcga tgcgccagcc aagcacacct aatttttcct cggcgcttaa
    20221 tattactagc ggcaatgaaa atggtagtgc gatgcagcta cgagggtcag aaaaagcgct
    20281 aggaacgctc aaaatcacac acgaaaaccc aaacgttgag gcaaattacg atgaaaacgc
    20341 tgcagcgtta tctattgata tcgttaaaaa acagaaaggc ggaaaaggta ctgctgctca
    20401 aggaatctac attaactcaa catcaggcac agctggtaaa atgctcagaa tcagaaatga
    20461 aaataaagac aaattttatg taaatccaga tggtggcttt tggtcatgtg caaattcaac
    20521 tgtaactggt aatctaacag ttaaagatcc aacatctgaa aaacatgctg cgactaaaaa
    20581 atacgtagat gaaaaaattg ctgagttaaa aaaactcata caaaaaacag attaaggagg
    20641 ataaatgagt agagacccaa cactaacatt agacgagtca aatttaacga tcggctcaga
    20701 tggacgtgct tattatacat ttacggctga tgataacaca aaaagcgtta aaatagccaa
    20761 cgacaaatgt atcggtacaa ctcgctttaa ccagctcatg attgagcgag gagataagcc
    20821 aactaattac gtggcgcccg tggttgtcga ggggacaggt aatccgactg gactatttaa
    20881 agacctcaaa gagcttaatt tagagctgac agatactgct aactctcagc tctgggcaaa
    20941 aatcaagcta aacaatcatg gtatgttaca gacatacttt gatacgacta ttaaaaatga
    21001 gattttaaca acggctcaag gtatcagaga gactatctct gacactaaga gaggtcttag
    21061 atccgagttt ttaaaaacag tgcaaggtca gcgtatccag cttgagagtt tgctagagca
    21121 aaagaccgct caactcggct tgacggtcga tggtctaaaa cttgatttaa acaaagcaaa
    21181 caaacagaca gctagtttac aggctagtat caatggtttg cgacaagact atcaagatgc
    21241 tgataggcgc ttatccgcaa gttaccagtc tggcattaac ggcctaaaag ctcaactagc
    21301 caatgataaa atcggtttac aagctgagat acaagcaacc gctcaaggat tatcacaaaa
    21361 gtatgataac gagctaagac agttatcggc taagatcaca acaacctcaa gcggcactac
    21421 agaggcctac gagagtaagc ttgcgggctt acgtgctgag tttactcgct caaatcaagg
    21481 cacgaggaca gagctcgagt cacaaattag cggactaaga gcggtacaac agacaaccgc
    21541 tagccaaatc tcacaagaga tacgtaaccg tgaaggtgct gtcagtcgtg tacaacaggg
    21601 cctagacagt tatcaacgac gattacagtc cgcagagggt aattacaaca gtttgagaga
    21661 gactgtagcg ggttatgagc gcaggatatc caatcaggat aacactatct cctctaactt
    21721 tactcagcta aagactttga tagatcagtc tgtgaccttg gagaaggtcc agtcgctctt
    21781 gcggcaatct ggtgatagta tcatgctcgc gattaaggac aagttgccta agagcaagat
    21841 gtctggtaat gagataatct cagcgattaa cctaaactcc cacggtgtgc aaatagctgg
    21901 taaaaacatc actcttgatg gcaataccac tgtcaacggc gcttttacca caaagattgc
    21961 caacgctatc aaaatcaagg ctgaccagat tatcgcagga gtgattgacg ctgctaagat
    22021 tagagtgatt aatctaaacg ccagcagtat cgttggttta gacgctaact ttatcaaagc
    22081 taaaattggc tatgcgattg ttgacatgct tgagggtaaa gtgattaagg cacgcaatgg
    22141 cgctatgctt attgatctta gctcggctaa gatggatttt aatagtaatg cgaccatcaa
    22201 ctttaacagt cgtgataacg ctctggtccg cagggacgac acacacactg cctttgtaca
    22261 ttttagtaat gccacaccaa aaggttatac agggtcagcg ttgtatgcat cgatcgggat
    22321 aacctcatct ggtgacggtg ttaactcggc ttcttccggt cgttttgcag ggctaaggtc
    22381 atttaggtac gctacgggat ataaccatac tgctgcagtc gaccagacag aaatttatgg
    22441 tgataatgta cttattgcag atgactttaa catcaatcga ggatttaagt ttagaccaga
    22501 caagatgaca aaaatgattg atatgaacga cttgtatgcg gctgtagtag ccttaggacg
    22561 ttgttggaag cacttagcta acgttggctg gaataccgtt catggcaatt ttgtaagtgc
    22621 tgtgaatggg gaattgaata actacatcac aaaaatttaa caggagataa tatgcaatta
    22681 actattaaaa acaaagattt aaacacacta tattgtgtac tagacaaaat caaagtcacg
    22741 aacatgcgag caaaccgcgg acgtgctaag ctactcgcaa aagtagtaga taaattcaaa
    22801 gagtacgcca aggatgaggg tgaccttatt gatctgtatg ctcaaaaaga caaagatggc
    22861 aagtttgtca ttgatgagca caaaaacatc aagctagcag accccactaa actcgacgag
    22921 ttcagcggcc tactcaacga gctagctgat gaagaaattg tgattaaagg gggtgagtac
    22981 tctaagcgat ttattgactt tttaaacttt ttagaagagt gtgaagatga atttacatca
    23041 tctgaaatca ttcttatcga cagcattttg gaacaatttg aagaaagtaa aaaaggagaa
    23101 taaccatgag aaattggaaa gtgacaggaa aatatccaca atttgacagc acaggagcag
    23161 tcgcaagcac acatattatt atcacagcag aagatggctc agtcatctct caaccaatca
    23221 agcaggactt aaactcaact aatgacacag agattatcaa agccgctttg gaagaattta
    23281 aaaaatctga atacgttgaa attgcaatgg gcgaagccgt gcaaaaagta gacgaccttg
    23341 aaaaaatctc acaggaaacc gctaagactg ctaaaacagc ccaaacagct gctggactag
    23401 ctaaggtgtc cgcagagcgc acgcaaaaga tgattaactt acaaacgatc cacatgttaa
    23461 cgagcggcgg caagattgat cctgatatct ataaaggtct tttagagctt attgagcctg
    23521 ctaaacaagg tgagtatcaa gcctatgatg tctttactgt tgtagacgag tcgcacgaag
    23581 agcaggcagg agaaggtaat cttgtctttg tacacgttaa cgagccattt acttatgaca
    23641 aacagacgct taaagagcta gaggaagagg ataaagtcac agtcattaaa tatgcggatt
    23701 tggttaaaca agattagagg tggttagatg atagattttg tacaaattgg tgctttttgt
    23761 ggcgctgctt tgtctatctt gggtgtttgg ggatttatcg tcaatccctt taaaaaagcc
    23821 atggaagcta atgagtttgc catggctcaa ctcaaggact caattaagga gttagcttat
    23881 gagcttaaaa atcttgatcg tgaccgtgag attaccaaaa aaattatcga ccgccacgaa
    23941 gagcgtttag gtcgtgtcga agatgaagtc attattaata aggagcgtat tgtcacgctg
    24001 tttaaaaaag gagaagaaaa atgaacaaat ggtttaaaaa agtagcaatc aaaacaatta
    24061 agacaatggc acaaactgcg gttggtctta tcgggtcaag catgttgatt acggatatta
    24121 actggcctac tatgctatca gcagtgttgt tgtcaggact tacttgtgtc ctcatgaatg
    24181 tgtcacaaat caaggaagag gaataagcca tgcgagcagt cacacgatta gcattagtta
    24241 tagcaatcgc aatactgtat gttccgctgt ctgtgattg
//
LOCUS       DATTYN010000033        23989 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.33, whole genome shotgun sequence.
ACCESSION   DATTYN010000033 DATTYN010000000
VERSION     DATTYN010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23989
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.33"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(223..1365)
                     /locus_tag="VB649_001527"
     CDS             complement(223..1365)
                     /locus_tag="VB649_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEP1670470.1"
                     /translation="MTINRVLKDDNLLQYTEKEFIEDMKILVAIDSFKGSVTSPELNT
                     SVAQALLSVDKQLVIETRAIADGGEGSLAALSQTVAGRWHQVKTIDLLRRPIKVAYYR
                     HAKQAFIESASIIGIDKITPNSVTYAQATSYGLGLAVKDAIQKGATQIEIMLGGTGTS
                     DGGKGFLESLNYDFMTGRSYLDTLASPVTLLGLTDVTNPYHGPQGFAAVFGPQKGGSL
                     SQIEETDQIASNFAKKVFYQTTIDLQTIPGSGAAGGLGGAIVLLGGTLTSGFSRIAEL
                     LNLDNSLQSCDLVITGEGCLDTQSQSGKVPVAIARMAKKYQVPTIALCGSVKIETGLA
                     AEDFLAVFSIQQQPISLEAAIDKTTTLSNIKILAANLMLLIAQFNK"
     gene            1646..4624
                     /locus_tag="VB649_001528"
     CDS             1646..4624
                     /locus_tag="VB649_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEP1670471.1"
                     /translation="MGNQTKTELELEKELIHLLETGESQWTYRKELKTEDALWDNFFK
                     ILAQNNTQYLNEEPLTASEKEQIKNQLNFVNYYEAAKWLAGENGIAKVQVQREDAKLG
                     TIRLEVVKADNVAGGTSVYEIANQVAFSGSRDRRGDVTLLINGLPMIQIELKSQNHQC
                     IEAFNQVKKYDKEGQFRGIFSTLQMFVVSNKTDTRYIAAAKENKLNPNFLTQWVDQNN
                     KPQKDLFAFAKEVLSIPRAHQMVMTYSVIDDDKKALILLRPYQIHAIEAVAEASRHRQ
                     SGYIWHTTGSGKTLTSYKVARNILQIPAVEKSIFVIDRKDLDNQTTSAFQSYAQNDIF
                     DVDETEDTRQLIKNLESSDRRVVVTTIQKLNAMISQMESYDTPKFKKLKERLEHLNVV
                     FVVDECHRAVTPERQRHLTNTFRNSRWYGFTGTPIFMENKRAQLGDLAQTTEQQYGKC
                     LHQYTVKEAIHDKAVLGFQVEYKTTIPDMPEDSIPEEAYDHEEHMLAVLNSIINQSRK
                     KLGFNNGIGQTFEGLLTVKSIARAQAYYDLIQKVKAGETDLVISKKVKEKLPDFPKVA
                     ITYSITENDNASISRQDKMTKNLEDYNHLFGTNFTIDNLQGYNRDLNDRLARKKDKFK
                     DRHEQLDLVIVVDRLLTGFDAPCLSTIFIDRQPMKPQHIIQAFSRTNRIFESRKHYGQ
                     VVTFQTPLRFKEAVDKALSLYSNGGENDVLAPSWEEEKARFFEKVTVLKNIVPDPDAF
                     PTIESAQTAFLKQYAKAFQAFDKLFASVQVYSDFNETLLSEVGLSDEVIDTYKGTYQN
                     VIAEIRKRREDDEAIPEINIDYELESVQMDDINYHYILTLIQAFVDQEQEALQERLND
                     NPMDQYIQDLAKSNPAMADSLAELWQDIQKEPKAYEGKSIAYELDNLIGDKIQRAIKH
                     FADQWKADPDKLAFVATNYHSANSTKQVGMSTLKESLDYQAYKEKQGDSAMNKLKYKS
                     QFERELVQFIRDQIQPLKGH"
     gene            4637..5836
                     /locus_tag="VB649_001529"
     CDS             4637..5836
                     /locus_tag="VB649_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEP1670472.1"
                     /translation="MTKSKQPQYRFDSFEGEWEEKELGDIVQITMGQSPSSQNYTTNP
                     SDYILVQGNADIKNGYVFPRVWTTQITKQADKGDIILSVRAPVGDVGKTNYHVIIGRG
                     VAAIKGNEFIFQILKYLKEIGYWKRISTGSTFDSISSSDIKYAKIQIPSLPEQEAIGE
                     LFQTVDQLIQLQDQKLATLKEQKQTFLRKMFPPQGQKVPEIRLQGFDGEWEEKKLGEI
                     STHRSGTAIEKYFDSEGEFKVISIGSYGTNNLYVDQNIRAVSNELTNSKLVASGELTM
                     VLNDKTANGAIIGRCLLITENNKYVVNQRTEIIRPDINISSYYLFHYLNGEFRNGIIK
                     IAQGGTQIYVNYSSVEQLKINIPTLKEQEAISNFFQTLDQQIAQSEEKLTELKALKQT
                     LLNRLFV"
     gene            5849..7429
                     /locus_tag="VB649_001530"
     CDS             5849..7429
                     /locus_tag="VB649_001530"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEP1670473.1"
                     /translation="MAEKTTSLRQALWHSADQLRGQMDANDYKNYLLGLIFYKHLSDK
                     LLLAVCDNLEKHFNTFTEAQKIFEDAYQDEGLKDDLISVVTGDLGYFIEPTLTFEKLI
                     QDVYHNTFQLESLAQGFRDIEQSGEDFENLFEDIDLYSKKLGSTPQKQNQTISNVMKT
                     LNEIDFEAVDGDTLGDAYEYLIGEFASESGKKAGEFYTPQAVSHLMTQIVFLGREDQK
                     GMTLYDPAMGSGSLLLNAKKYSNQSDTVSYYGQEINTSTYNLARMNMMLHGVAIENQH
                     LSNADTLDADWPTDEPTNFDGVLMNPPYSLKWSATAGFLTDPRFSSYGVLAPKSKADF
                     AFLLHGFYHLKNTGTMAIVLPHGVLFRGAAEGKIRQKLLGQGAIDTIIGLPSNIFYNT
                     SIPTTIIILKKNRTNKDVFFIDASKEFDKGKNQNTMTDDHIKKILDAYKSRDNSDKFS
                     YLASFDEIIENDYNLNIPRYVDTFEEVPVKPLPELAKQLSDIDQEIAKTNAKLDQLMK
                     QLVGTTKEAQDELDTFRN"
     gene            complement(7981..8586)
                     /locus_tag="VB649_001531"
     CDS             complement(7981..8586)
                     /locus_tag="VB649_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1670474.1"
                     /translation="MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLS
                     KYDIILLDINLTNISKENGLEIAKELIQSTPYLKVVMLTGYVKSIYRERAKKVGAYGF
                     VDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
                     TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF"
     gene            complement(8567..10129)
                     /locus_tag="VB649_001532"
     CDS             complement(8567..10129)
                     /locus_tag="VB649_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670475.1"
                     /translation="MIRIKNITKSKFFGTAIILLQQLIALLILVYNRENLSLLFSEKV
                     ALVMTLIDTAFIWLATILRQKQGDIFKRIISIISLTIWQYLVSVLTRGTPLFLSSGLQ
                     IILLYCYTVEITNLILYGHKQFKDKLDKGLLIIIFVSITSLFVNRILFNFLFLIVFTI
                     LHLYPLLVIVLYYRSFRQQISVVRRSLILFSLLLLVILGSEFYGEMLDVNQAFNNLGW
                     YLFPLIMSVIYYFKTIHDKLSFVTQRWLGNYKARIELLFLLLILCWIVLMKVLVKDFL
                     LFFIVVDASTLFCLVVISCIFYYLKDSKQNFDYENRRLNYFMKSEENMRVEFSNYLHD
                     DVLQNIIAIKNLLSLENSNITHGFIVSELNDLVSGIRDEMDTYHPIVPANQTMKENIQ
                     SLFDDIVKSRKSNTLLYFNCSDNMVVPSPYGDIVYRFIKELINNAIKYGDGKDIRLSL
                     TIQSDIIIIEESNQVVEKVHSISYGRGLKSFQETLAAFDGDLELQMDTKQFTIRILLP
                     IDWKLCYEDFIN"
     gene            complement(10169..12076)
                     /locus_tag="VB649_001533"
     CDS             complement(10169..12076)
                     /locus_tag="VB649_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEP1670476.1"
                     /translation="MIWSITKSNIKKNFSLYRIYFLATIGLLSIFIAFLNFISDKIIT
                     EKIGDSGQALVIANGSLIFLIVFLVVFLIYFNNFFVKKRSQELGVLAILGFSKKELTQ
                     LLTLENLVILVLSYLVSLLLGPTLYFLAVLVITHLLELTLEVQWFITANEIIESLGIL
                     VVVFLINVITNGLIISKQSLIEFVNFSRKAEKKIKIRKVRAITAITALLLSYILCLAT
                     VFSFTRNMLLSIGMVPVSLLIIVLVVLGTVFTIRYGLAFVVSLLKENKKRLYRPLSNI
                     IYPKFNYRIATKNKLLTVLGGLLTITVSVAGMMVMLYAYSLNGIERLTPSAIEYNVKS
                     ENGRVNVTTILENDQVSLVDVGLLRLNTIPEVTITDSGQTIPYFDIINYSDYKELMKA
                     QGRTNSIEGSKSLPLLINYYPTEISLGKTFNLGNAYDVTVKQVSTHNVFSFSTSVTTL
                     VVSDKLYAKLSSCFPEKEMTIRTFNGNSIRSSEAFYNQFSMVPDVISSYSKEYTVKTA
                     NIATYIFITFLSILFIICTGSILYFTSLIEIMENKEEYGYLSKLGYSKKMIHRILRYE
                     TGILFLIPVFIGIVNGGMLLIYYKYLFMDTLVAGNIIMLSLLLCLLFFLIIYGTFYVL
                     TLRSVTSIIKN"
     gene            complement(12078..12815)
                     /locus_tag="VB649_001534"
     CDS             complement(12078..12815)
                     /locus_tag="VB649_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000812013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670477.1"
                     /translation="MKQLVLKDVCKKYPNQLNYALDHINLIVEKGEFVAVMGRSGSGK
                     TTLLNVTSIIDKIDSGNIYCADKEISTFSDKEATNFRKNDIGFVFQDYMLLDSLTIRE
                     NISVALSLKNIDSSKIDDLINSYAKRFNLYEQLKKYPYQLSGGQRQRVSIIRAIIKEP
                     EIIFADEPTGALDLKSSEETMMILSEINKTEKVTILMVTHDVLSASYADRVILLKDGK
                     LHMEIDKKDCGESFYDVISQALSDRGE"
     gene            complement(12812..13345)
                     /locus_tag="VB649_001535"
     CDS             complement(12812..13345)
                     /locus_tag="VB649_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670478.1"
                     /translation="MDKTDFRNISAFVSQDSPIFDGDVMYNISLGRESVTEKQVIETC
                     KRVSLYEDIRSMPMKFHTPLFRDNPSLSGGQKQRISLARELVTTPRILVLDEPTSDLD
                     VKTERIIQKSVEALHCTRVLVTHRLNTVEKADKILIMDNGKIIDYGNHHYLYKNNKDY
                     CDLYDSYMNKYQEEEVK"
     gene            complement(13347..14972)
                     /locus_tag="VB649_001536"
                     /pseudo
     CDS             complement(13347..14972)
                     /locus_tag="VB649_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561003.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
     gene            complement(15055..15210)
                     /locus_tag="VB649_001537"
     CDS             complement(15055..15210)
                     /locus_tag="VB649_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A2 lantipeptide"
                     /protein_id="HEP1670479.1"
                     /translation="MSFMKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCP
                     NSVFVCC"
     gene            complement(15713..17119)
                     /gene="lacG"
                     /locus_tag="VB649_001538"
     CDS             complement(15713..17119)
                     /gene="lacG"
                     /locus_tag="VB649_001538"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEP1670480.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFAEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKNGGYSGEIGVVHAL
                     PTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDL
                     REEDFAALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     KAPVDVPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVISDAISDGVNVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(17207..18904)
                     /locus_tag="VB649_001539"
     CDS             complement(17207..18904)
                     /locus_tag="VB649_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEP1670481.1"
                     /translation="MNGLIAQIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIENLLMTPYNYSMGILGLFVAGTTAKALTDSMNRSLPSTNQ
                     INFMSTMLAAIVGFLLMAANPAKEGGFLTGFMGTKGLLTAFIAAFITVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTLSVVLLYVIELIVHSTLGVNVAESIGKLLAPLFQ
                     AADGYVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAETNLQLLQAGEHADKIL
                     TSGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPL
                     VLNPIFFIPFILAPIVNVWIFKFFIDTLGMNSFTANLPWTTPAPLGLILGTNFQVLAF
                     ILAALLIVVDVIIYYPFLKIYDEQILAEEAAGTNSSDALKEKVAANFDTKKADAILEK
                     SAAKETKEITDQTNVLVLCAGGGTSGLLANALNKAAKEYGAPVTAAAGSYGAHREILP
                     QYQLVILAPQVASNYEDMKVETDKLDIKLAKTEGAQYIKLTRDGQGALDFVKAQFEN"
     gene            complement(18904..19221)
                     /locus_tag="VB649_001540"
     CDS             complement(18904..19221)
                     /locus_tag="VB649_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEP1670482.1"
                     /translation="MNREETTLLGFEIVAYAGDARSKFLEALKAAQEGDYAKAEELIA
                     AGSDCLNDAHNAQTSLLQKEAAGDDLAYSVTLMHGQDHLMTTILLQDLMKHMIELYKR
                     GAK"
     gene            complement(19245..20228)
                     /gene="lacD"
                     /locus_tag="VB649_001541"
     CDS             complement(19245..20228)
                     /gene="lacD"
                     /locus_tag="VB649_001541"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEP1670483.1"
                     /translation="MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKE
                     PTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTT
                     SRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDINEQKKAYIERIGSECRAEDIP
                     FYLEILTYDEKISDNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEG
                     FADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVL
                     CGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM"
     gene            complement(20232..21158)
                     /locus_tag="VB649_001542"
     CDS             complement(20232..21158)
                     /locus_tag="VB649_001542"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEP1670484.1"
                     /translation="MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSR
                     VLNEFGETVKATGCIGGESGDFIINHLPDSILSFYKISGDTRTCIAILHEGNQTEILE
                     KGPMLSVDEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIGIANLNGKKTVL
                     DCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTRDFDALKEVLQDKLFDGIEWII
                     VSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKAN
                     VLGMLNAQEKTTGHVNMANYDKLYQSIKIKEV"
     gene            complement(21204..21719)
                     /gene="lacB"
                     /locus_tag="VB649_001543"
     CDS             complement(21204..21719)
                     /gene="lacB"
                     /locus_tag="VB649_001543"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEP1670485.1"
                     /translation="MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPI
                     FGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNAN
                     VIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEF
                     LEKWDRGEYHD"
     gene            complement(21754..22182)
                     /gene="lacA"
                     /locus_tag="VB649_001544"
     CDS             complement(21754..22182)
                     /gene="lacA"
                     /locus_tag="VB649_001544"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEP1670486.1"
                     /translation="MAIIIGADKAGQELKEVIKDYLKEGKHEVVDVSENEVRDFVDTT
                     LAVAKEVNASEDNLGIVIDAYGVGSFMVATKIKGMVAAEVSDERSAYMTRGHNNARII
                     TLGSEISAPGIAKNIIKGFVEGKYDGGRHQVRVDMLNKMC"
     gene            22627..23400
                     /locus_tag="VB649_001545"
     CDS             22627..23400
                     /locus_tag="VB649_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004270277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEP1670487.1"
                     /translation="MKKKERHEKILDILKVDGFIKVKDIIDEMNISDMTARRDLDTLA
                     DKGLLIRTHGGAQYLDYSSAKDEGHEKTHTEKKVLQTTEKKQIAQRAKNIIKDGETVF
                     IGPGTTLEHLAVELKNRNIRVITNSLPVFLILHPSTTIDLILIGGECREITGAFVGAI
                     AINNLESLTFSKAFVSANAVYNNSIATYSDLEGEVQRVGLNNAVEKILLVDSTKFESY
                     DFYNFYQLDQVDLIVTDKNVTTDIIEKYKKFSKIIIADK"
BASE COUNT         7941 a         4518 c         3768 g         7762 t
ORIGIN      
        1 atggcctgtc aactactttt tcatcttttt tcaataagtg tgttacaaga acctctctga
       61 cagctttatt agtatacgat atctttactg tcattgtcaa ctcttttttt acaaaatgtt
      121 tctgtttttc atactatgct aatgagttag ctcgtgcgtc tccttcttca taggttactt
      181 ttaaccgcca aatgaatgct acacaatcga aaatagatga gtttacttat taaactgagc
      241 tatcaatagc ataaggttag ctgctaatat tttgatatta gaaagtgttg ttgttttatc
      301 tatcgctgct tctaaggaaa ttggctgctg ttgtattgaa aaaacagcca aaaagtcttc
      361 tgctgctagt cctgtctcaa tctttacaga accacataga gcaatcgttg gaacctgata
      421 ttttttagcc attcttgcaa tcgcaacagg taccttgcca gattgtgatt gtgtatccag
      481 gcatccttct ccagtaataa ctaaatcaca agactgaagg gaattatcca gatttagtag
      541 ctctgcaatc ctgctaaaac cactagttaa ggtgcctcct aataggacaa tggcacctcc
      601 taatcctcca gctgctccac ttcctggtat tgtctgtaaa tcaatggttg tttggtaaaa
      661 aactttttta gcaaagttac ttgcaatttg atcagtttct tcaatttgac taagactccc
      721 acctttttga gggccaaaga ccgcagcaaa tccttgaggg ccatgatatg gattggtcac
      781 atcagtcaga cctaatagcg taacaggtga tgctaaagta tcaaggtaag atcttcctgt
      841 catgaaatca tagtttaaac tttccaaaaa ccctttgcca ccatcagaag tgcctgttcc
      901 tcctagcatg atttcgattt gagtagctcc tttttgaatg gcatctttaa ctgccaaacc
      961 caaaccatag gaagtggctt gtgcataggt tactgaattg ggggtgatct tatcaatacc
     1021 aataatactc gcagattcaa taaaagcttg ctttgcgtga cgataataag cgactttaat
     1081 cgggcgtctt aatagatcaa tggtttttac ttgatgccac ctccccgcca cggtttgtga
     1141 gagggctgct aaacttcctt ctcctccatc agcgatagct cttgtttcaa taactaactg
     1201 cttatcgaca gaaagaaggg cttgagctac actagtgtta agttctggag acgttaccga
     1261 tcccttaaaa gaatctatgg ctaccaaaat tttcatatct tcaataaatt ccttttctgt
     1321 atattgtagc agattatcgt cctttaaaac cctattaata gtcaagctag atctgtctta
     1381 agttttttat ctattttgag aactcgacct ttttactagt gttgtcttat tactttcttc
     1441 accttaaatt attgtcaagc aaactcaaaa atacaagaac tttctcgatt gcatttacat
     1501 agtcatagct ttgtttagtt gctaggatct taagcattca actaatcaga aaaagactgt
     1561 ttggaaggtt tcaatagctt tgccattcta aaaaggatcc gccaatgata taatactact
     1621 atatcatgtc gaatggggat taaaaatggg aaatcaaact aaaacggaac ttgaacttga
     1681 aaaagagttg atccatctct tagaaacagg tgaaagtcaa tggacatatc gtaaagaatt
     1741 aaaaactgaa gatgctttat gggataattt ctttaagatc ttagcgcaaa ataacacgca
     1801 atatctgaat gaggagcctt taacagctag tgaaaaagag cagattaaga atcaacttaa
     1861 ctttgtcaat tactatgaag cggctaaatg gttagctggt gaaaacggca ttgctaaagt
     1921 acaagtgcaa cgcgaagatg caaaactagg aacgattcgt ttagaagtcg ttaaagcaga
     1981 caatgtggct ggtggaactt ctgtttatga gattgccaat caagttgctt tctctggttc
     2041 tcgtgataga cgaggtgatg tgacacttct catcaatggc ttacctatga tccaaattga
     2101 attaaaatct cagaatcatc aatgcattga agcttttaac caggtcaaaa agtatgataa
     2161 agaaggccag tttagaggta tcttttcaac cttacaaatg tttgtggtct caaataaaac
     2221 agatacaagg tatatcgctg cagctaaaga aaataaatta aaccctaact tcttgaccca
     2281 atgggtagat caaaataaca aaccacaaaa agatctcttt gcctttgcca aagaagtcct
     2341 atctatccct cgtgctcacc aaatggtcat gacttactct gtcatcgatg atgataaaaa
     2401 agcactaatt ctccttcgtc cttatcagat tcatgcaatc gaagccgtcg ctgaagcgag
     2461 tcgtcaccgc cagtctggct atatctggca cacaacaggt tctggaaaaa ccttaacttc
     2521 ctataaagtg gctcgcaata tccttcaaat accggccgtt gaaaaatcca tctttgtcat
     2581 tgaccgaaag gatttagata atcagaccac ttctgctttt caatcttatg cgcaaaatga
     2641 tatctttgat gtcgatgaga cagaagatac gagacaactc atcaaaaatt tagaatccag
     2701 tgatcgtcgt gttgtggtca ccaccattca aaaactcaat gctatgatca gtcagatgga
     2761 aagttatgac actccaaaat tcaagaaact aaaagagcgt cttgaacacc taaatgttgt
     2821 ctttgttgta gacgaatgcc accgtgctgt cacaccagaa cgtcaacgtc atctcacgaa
     2881 tacttttcga aacagtcgct ggtatggctt tacaggtact cctatcttta tggaaaataa
     2941 gcgtgctcaa ttaggtgatt tagcccaaac aacggaacag caatacggca aatgtctcca
     3001 tcaatacact gtcaaagaag ccattcacga taaagcggtt ctaggcttcc aagttgagta
     3061 taagacaacc attcctgata tgcctgaaga cagtattcct gaagaagctt atgatcatga
     3121 agaacatatg ttagctgtct taaatagtat cattaatcaa tcacgtaaga agcttggctt
     3181 taataatggg attggtcaga cattcgaagg cttattaacc gttaagagta ttgctcgtgc
     3241 ccaagcctat tatgatctga ttcagaaagt taaagctggt gaaacggatt tagtcatttc
     3301 taagaaggtc aaagaaaaac taccagactt tccaaaggta gctattactt attctatcac
     3361 tgaaaatgac aatgcgtcta tcagccgaca agataaaatg accaaaaatc tagaagacta
     3421 taatcacctc tttggcacta actttaccat cgataactta caaggctata acagagattt
     3481 aaatgatcgc ttagcccgta aaaaagataa attcaaagac cgtcatgaac aattagacct
     3541 cgtgattgtg gttgaccgtc tcttaacagg ttttgatgcg ccttgtttat caacgatctt
     3601 tattgatcgc cagcctatga aacctcagca cattattcaa gctttctcac gaaccaaccg
     3661 tatctttgaa agtagaaaac attacggtca ggttgtgact ttccaaacac cacttcgttt
     3721 taaagaagct gtcgacaaag cgcttagcct ctactctaat gggggtgaaa acgacgtttt
     3781 ggccccttct tgggaagaag aaaaagcaag attctttgaa aaagtaacag tattaaaaaa
     3841 tatagttcct gatccagacg ctttcccaac tattgagagc gcacagacag cttttctcaa
     3901 acaatacgcc aaagcctttc aagcatttga taaactcttt gcatctgtac aagtctatag
     3961 tgactttaat gaaacactat tgagtgaggt tgggttatca gatgaagtga ttgatactta
     4021 taaaggcact taccaaaatg tcattgcaga aatacgaaaa cgaagagaag atgacgaagc
     4081 catcccagag atcaatatcg actatgagct agaaagtgtt cagatggatg atatcaacta
     4141 tcactatatc ttgaccttaa ttcaagcctt tgtcgatcaa gaacaagaag ctcttcaaga
     4201 aaggctcaat gacaatccca tggatcaata catccaagat ttggcaaaat caaaccctgc
     4261 tatggctgac tcactagctg agttatggca agatatccaa aaagaaccca aagcctatga
     4321 agggaaaagc attgcttatg agttggataa cctcattggt gataagatcc aaagggccat
     4381 caaacacttt gcggaccaat ggaaggcaga tcctgacaaa ttagcctttg tggcgactaa
     4441 ttatcatagt gctaactcta ccaaacaagt aggcatgtca accttaaaag aatccctaga
     4501 ctaccaagcc tataaagaaa aacaaggtga ctcggccatg aataaactca aatacaagag
     4561 ccaatttgaa cgggagttag ttcaattcat tagagatcaa atccaaccct taaaagggca
     4621 ctaggaaagg aaagagatga caaaatctaa acagcctcaa tatcgctttg acagttttga
     4681 aggggagtgg gaagagaagg aactaggtga tattgttcaa attacaatgg gccaatctcc
     4741 atcaagtcaa aattatacta caaatccttc tgattatatt ctagtacaag gaaatgccga
     4801 tataaaaaat ggatatgttt ttccgcgtgt ctggacaaca caaattacaa aacaagctga
     4861 caaaggtgat attattctta gtgttagggc tccagttggt gatgttggaa agacaaatta
     4921 tcatgttatt attgggcgtg gagttgctgc tataaaaggt aatgaattta tctttcaaat
     4981 attaaaatac ttgaaagaaa ttggttattg gaaaagaatt agtacaggtt caacttttga
     5041 tagcattagc tctagtgata tcaaatatgc taaaattcaa attccctccc tccctgaaca
     5101 agaagccatt ggcgaacttt tccaaacggt tgatcaattg attcagttgc aggatcaaaa
     5161 gctagcaact ctaaaagaac aaaagcaaac cttcctcaga aagatgttcc cacctcaagg
     5221 acaaaaagtc cctgaaatcc gtttacaagg ttttgatggt gagtgggaag agaagaaatt
     5281 gggagaaata tctactcata gaagtggaac ggcaattgaa aaatattttg attcggaagg
     5341 tgaatttaaa gtcatttcaa taggtagtta tggaactaat aacctctatg tagaccaaaa
     5401 tattagagca gtctcaaatg aacttactaa ttctaaatta gttgcctccg gtgaattaac
     5461 aatggtactc aatgataaga cagcgaatgg ggcaataatc ggaagatgtc tacttattac
     5521 agaaaataat aaatatgttg ttaatcaaag aacagaaatt attagaccag atattaatat
     5581 ttcctcttac tatcttttcc attatttaaa tggtgaattt cgtaatggta tcattaaaat
     5641 tgctcaaggt ggcactcaaa tctatgtaaa ttattcatct gttgaacaat taaagataaa
     5701 tatacctaca ttaaaagaac aagaagccat tagtaatttc ttccaaactt tagaccaaca
     5761 aattgctcaa tctgaagaaa aactaacaga actcaaagca ctcaagcaaa cattactcaa
     5821 tcgtttattc gtataagaaa ggactcacat ggcagagaaa acaacttcac tccgtcaagc
     5881 actatggcat tcggccgacc aattacgtgg ccaaatggat gccaatgact ataaaaacta
     5941 tcttcttgga cttatttttt acaaacactt atctgataaa ttactcttgg ctgtttgtga
     6001 taatctagaa aaacacttca atacctttac agaggctcaa aaaatctttg aagatgctta
     6061 tcaagatgaa ggcctaaaag atgacctcat ttctgttgtt actggtgatt taggttactt
     6121 tatcgaacca acactgacct ttgaaaaact catccaagat gtttatcaca atactttcca
     6181 attagaatca ttagctcaag gttttcgcga tattgaacaa agtggtgaag actttgaaaa
     6241 cttatttgaa gatattgacc tctactctaa aaaattaggc tctactcctc aaaaacaaaa
     6301 tcaaaccatt tctaatgtca tgaaaacatt aaatgaaatt gactttgagg cagtagatgg
     6361 ggatacttta ggcgatgctt atgagtactt gattggtgaa tttgccagtg agtcaggaaa
     6421 aaaagcaggt gagttctata ccccacaagc tgtctctcac ttgatgactc agattgtctt
     6481 tttaggtcgt gaagatcaaa aaggaatgac cctctatgac cctgctatgg gatctggatc
     6541 actcctttta aatgctaaga aatatagtaa ccaatccgat accgtttctt actatggtca
     6601 agaaatcaat acttctactt ataacttggc tcgtatgaac atgatgcttc atggcgttgc
     6661 catcgaaaac caacacttaa gtaacgctga taccttggat gcagactggc caacagatga
     6721 gccaaccaac tttgatgggg tgttgatgaa cccaccttat tctttgaaat ggtcagcgac
     6781 tgctggtttc ttaacggatc cacgtttttc aagttatggt gtattagcac caaaatcaaa
     6841 agctgacttt gcctttttac ttcatggttt ctatcattta aaaaatacag gaactatggc
     6901 aattgtctta ccacatggtg ttcttttccg tggagctgca gaaggcaaga ttcgccaaaa
     6961 actactcgga caaggggcta ttgatactat catcggactc ccatcaaata tcttttataa
     7021 tacaagcatc cctacgacta ttatcatatt aaagaagaac agaaccaata aagatgtctt
     7081 ctttatcgat gcctcaaaag agtttgataa gggcaaaaat caaaacacaa tgacagatga
     7141 ccatatcaag aagattcttg acgcttataa gagtcgtgat aattctgata agttttcgta
     7201 cttagcctca tttgatgaaa tcattgaaaa tgactataac ttaaatatcc cacgctatgt
     7261 tgataccttt gaggaagtcc cagttaaacc actgccagaa ttagctaaac agctcagtga
     7321 cattgatcaa gaaattgcca aaacaaatgc caaactagat caactcatga aacaactagt
     7381 cggaacaacc aaagaagcac aagacgaatt ggatactttt agaaactaaa agacaaaaaa
     7441 acaccacagt agatgattac tactgtggcg ttttatttaa aattgagtag tgaaccttta
     7501 ttgagtactt atcatacaag attctccttc ttcacctata aatcaaaata gaatcatctc
     7561 atctaacttt gtccgttttc tttgttttat ttaaaatagt tatttgaagt tacaatgatt
     7621 tctcaaacgt ttagaaagct taaacacggt taagagaaat tttcaggaca acttttgatc
     7681 cttccacaaa aaccatggtg cgaaccataa agtagttcca atcgttgata tataagcata
     7741 tattaacgtt ctgggagttg tgaagcttta cgagtttttt tagacctggt ttaaacaact
     7801 ttgtttgact aaatttaaaa agcttttcat atcaggcatt gccctacttt ttataaaagc
     7861 gttatctcaa tcaatttcaa tcaaaaagaa cttaaaaaca atgagtttaa atctgggtat
     7921 ttaacaggaa acccctagca acgacacaag taaaacttat gtcgtttgat tatctgcaac
     7981 tcagaaatcc ataaaatacc ctaattgttc agctttgtag atagcctctt gcttgttatt
     8041 taccaaaagc tttgagtaga tgtgggtcaa atgattaaat actgttctcc tactaatttg
     8101 taacgtttcc tctatttctt ttatagagaa tcctttctta ctcaaattta agatagctat
     8161 ttcctggtca gttaaagatt caacataatc ctgagattcg atttgttcaa aatacttttt
     8221 tccagaatcc acttttttta agatagaaat gagttgttta gggtctatat ttttatctac
     8281 aaaaccgtat gctcctactt tttttgccct ctctctatag attgatttaa catatcctgt
     8341 caacataaca actttcaaat aaggagtaga ctgtatgagt tcttttgcta tctccaatcc
     8401 attttcttta gaaatatttg ttaaattaat atcaagcaat ataatatcgt acttagacaa
     8461 atcaatcgtc acatcgttaa aatgagaagt aatcgtatct atgacatcta cttcatcata
     8521 ctgttggaat aacagttgga tactctttgc aaatagtctg tggtcatcaa ttaataaaat
     8581 cttcataaca caatttccaa tctatgggaa gtaatattct gatagtaaat tgtttagtat
     8641 ccatttgtag ttctagatct ccatcaaaag ctgctagtgt ttcttgaaat gatttcaatc
     8701 ctctgccata acttatagag tgtacttttt ccactacttg attgctctcc tcaatgataa
     8761 taatatcaga ttgaatcgtt aaagataaac gaatgtcttt tccatctcca tattttatag
     8821 cattgtttat tagctctttt ataaacctat aaacaatatc tccatatggg gatggcacta
     8881 ccatattatc tgaacagtta aaatacaata aggtattact ttttctactt ttaacaatat
     8941 catcaaaaag agactgtatg ttttctttca ttgtttgatt agcgggaact attgggtggt
     9001 aagtatccat ttcatctctg ataccagaaa ctaaatcatt caactcacta acaataaaac
     9061 catgtgttat attactattt tctagagaaa gcaagttttt tatcgctatg atattttgta
     9121 aaacatcatc atgcaaataa tttgagaact ccactctcat gttttcctct gatttcataa
     9181 aatagttcag tcttctattt tcatagtcaa aattttgttt ggagtctttt aaataataaa
     9241 agatgcaaga aattaccact agacaaaaca atgtgcttgc gtcaacaact ataaaaaata
     9301 gcaaaaaatc tttaactaat accttcatga gtacaatcca acaaaggata agaagtagaa
     9361 ataatagttc tatacgagct ttgtaattac ctaaccatct ttgagtaaca aaactcaatt
     9421 tatcatgtat ggtcttaaaa tagtatatta cactcattat aaggggaaac agataccatc
     9481 ccaaattatt aaaggcttga ttaacatcta gcatttctcc ataaaattca ctaccaagta
     9541 ttaccagcaa aagtaaagaa aatagtatca atgaacgtct aacgactgat atttgttgcc
     9601 taaaagacct ataatatagc actataacta gtaacggata caggtgtaaa atagtaaaaa
     9661 caatcaggaa taaaaaatta aataaaattc tattaacaaa aaggctagtt atagaaacaa
     9721 aaataattat taacaagccc ttatctaact tatctttaaa ttgtttgtgc ccatataata
     9781 ttaaattagt aatctcaacg gtataacaat agagcaatat aatctgtagt ccactgctta
     9841 aaaagagagg agttcctctt gtcagcacag atactaagta ttgccaaatt gttaaggaga
     9901 tgatagaaat aatcctttta aaaatatcac cttgtttttg gcgtaatatt gttgccagcc
     9961 aaataaaagc tgtatcaata agggtcatta caagagctac tttttcagag aaaagaagag
    10021 acaggttctc tcgattatag accaaaatta acaaggctat taattgttgc aacaagatta
    10081 ttgcagtccc aaagaactta ctctttgtta tgttttttat tcttatcata ttatttactt
    10141 aatcgttaaa gttaaaagat ttttaaaatt aatttttgat tatggatgtc actgaccgca
    10201 atgtcaatac ataaaatgtg ccatatatta tcaagaagaa aagcagacaa agcaataaag
    10261 ataacattat gatattgcct gctaccaatg tatccatgaa taaatattta tagtaaataa
    10321 gcaacatacc accatttaca atcccaatga atacaggaat aaggaaaagt atacctgttt
    10381 catatcgaag aatccgatga atcatttttt tactataacc tagcttactt agatagccat
    10441 attcttcttt attttccatg atttcgatga ggcttgtaaa gtacagaata ctacctgtac
    10501 aaataataaa gagtatggat aggaaagtta taaagatata agtcgcaata ttagcagtct
    10561 ttactgtgta ttccttacta taactactga taacatcagg aaccatacta aactgattgt
    10621 aaaatgcttc acttgaccta atcgaatttc cattaaaagt cctaattgtc atttctttct
    10681 ctggaaaaca agaactaagt ttagcatata atttatcaga aacaaccaag gtcgtgacac
    10741 ttgtagaaaa actaaaaaca ttatgcgttg atacttgttt tacagtaaca tcatatgcat
    10801 ttcctaagtt aaaggttttt ccaaggctaa tttctgttgg ataataattt attaacaatg
    10861 ggagtgactt actaccttca atagaatttg ttctgccttg agctttcatt aactctttgt
    10921 agtcactgta gttaattata tcaaaataag gtattgtttg cccagagtct gtgatagtca
    10981 cctctgggat agtattcaat cgcaacaggc caacatcaac caagctcacc tggtcgttct
    11041 ctaaaatagt tgtaacatta acgcgaccgt tttctgattt aacattatat tctatggcag
    11101 atggagtcaa cctctctatc ccattaagag aataagcata gagcattacc atcattccgg
    11161 caactgaaac agttattgtt aaaagacctc ccaagactgt taataattta ttttttgttg
    11221 caatacgata gttaaattta ggatagatga tattagagag aggacggtat aacctttttt
    11281 tattttcttt taacaacgaa actacaaaag ccaatccata tctgatggta aacactgttc
    11341 ccaaaacaac taagacaatt atcaatagag aaaccggtac catccctatg cttaatagca
    11401 tatttcgtgt gaatgaaaat actgtcgcca aacataaaat atatgataat agcaatgcag
    11461 taatagcagt aatagctctg acttttctta tcttaatttt tttctcagcc tttcttgaga
    11521 aattaacaaa ttcaatcaaa gactgtttac taatgataag tccatttgtg atgacattaa
    11581 tcagaaaaac tacaactaat attcctaaag actctataat ctcattagct gtaataaacc
    11641 actgaacttc caatgttaat tccaatagat gagtaattac cagtaccgct aaaaaatata
    11701 aggtcggtcc caatagtaaa cttaccaagt aacttaaaac tagaataaca agattttcta
    11761 aagtcagtaa ttgtgttaat tctttttttg aaaaccctag tattgctaag actccaagct
    11821 cttgactacg tttttttaca aagaaattat tgaagtaaat taagaatacc accaaaaata
    11881 caatcaaaaa aatcaatgac ccattagcga taactagagc ttgaccacta tccccaattt
    11941 tttctgtaat gattttatct gagataaaat ttagaaaagc tataaaaata cttaataaac
    12001 caatcgtagc tagaaaatag atacgatata acgaaaaatt ttttttaatg ttagattttg
    12061 taattgacca aatcatatta ctctcctcta tcggataaag cttgactaat tacatcgtaa
    12121 aacgactctc cacaatcttt tttatcaatc tccatgtgaa gtttcccatc tttgaggagt
    12181 ataactctgt cggcataaga agctgataaa acgtcatgag taaccattaa aatagttacc
    12241 ttttctgttt tattgatttc actcaaaatc atcattgttt cctcagaaga tttcaagtca
    12301 agtgctccag ttggttcgtc agcaaaaata atctctggtt ctttaatgat tgctctgata
    12361 atactgaccc tctgtctttg acctccagaa agttgatacg gatatttctt caactgttca
    12421 tataaattaa atctttttgc atagctattt atcaaatcat caatctttga agaatcaata
    12481 ttttttagag acaaagcaac agaaatattc tccctaatgg ttagactatc taacagcata
    12541 taatcttgaa aaacaaaacc aatatcattt tttctaaaat tagttgcctc cttatcagag
    12601 aatgtgctaa tctctttatc cgcacaataa atattcccac tatcaatttt atcaataatt
    12661 gaagtaacat ttaaaagcgt cgttttccca ctaccgctac gccccatgac agctacaaat
    12721 tctccttttt ccacaatcaa attgatatgg tctagagcat aattcagttg attgggatat
    12781 tttttgcaaa catcttttaa tactaattgt ttcattttac ctcttcctcc tgatatttat
    12841 tcatatacga gtcatataag tcacaataat ccttattatt tttgtacaaa taatgatggt
    12901 ttccatagtc aataattttg ccattatcca ttattaaaat cttatcagct ttttcaactg
    12961 tattaagtct gtgggtaacc aaaaccctcg tacaatgtaa agcctcaaca cttttttgga
    13021 ttattctttc agtttttaca tctaaatctg atgtaggttc atcaagaact aagattctag
    13081 gggtagttac taactctctt gctagagaaa ttcgttgttt ttgcccccca gatagtgatg
    13141 gattgtctcg aaaaagtggg gtatgaaact tcattggcat actcctgata tcctcatata
    13201 gtgataccct tttacaggtt tcaataactt gtttttctgt aacagattct cttcctagcg
    13261 aaatgttata catcacatcc ccatcaaata ttggagaatc ttgagataca aaagccgata
    13321 tattcctaaa atcagtttta tcaattttag agaaggtaat gttctgagga gattgataaa
    13381 aactgataag atttgccctt ttccctctcc caatgcttaa tcggtttttt ctagactatt
    13441 tcaagcaatt cacaagtgaa cttcaatctt tcatcgttca aaatagttat actatcaaat
    13501 aacgaggttg tatctcctag atttccaatt aatgtcccta cagaattata gacgtttcct
    13561 ctggtatcca ttgaaaagta aggaatatca ccattcatca aatctttaat ttcattatca
    13621 acaataaaat gttcaatatg ttttgcctca tatagtatcg aaaataaatt ctccctcttt
    13681 ttttctgaga aaagatattt tggattcgta gaggcttgta aaaattttcc atagtcggaa
    13741 gtatttctga atatggctct agttttcaat tttgggaaat cttctaaaat ttttttaacc
    13801 tttgcacgtt gcgacatgag aaatgtatag cattctctaa aacctgcaat tacctcatta
    13861 gcatagtcga gaggttccac cactttccca tttaatgtcg gaatattata accatcttcc
    13921 tgaaaatagt cagttttcac taacttcata tctccacgat ttttatttat cagttcatac
    13981 tttccctttt ttcttttccc accttttcca cttatcccag aaacgttagg agcgctgttt
    14041 ttctcaaatt gtacaggaaa taaaccattt gaaagtgatg tcttataaat tctctgatag
    14101 gtgtctacag taatcccttc aaaattctga ttttgtacat tcaactttct ttgaaaaaag
    14161 gtttcaacgt caattaaata taaatctccg cctgaaacaa tcacattttc catatgtaag
    14221 tccgtaatag aaaatatttc agaaaatgct gctaaaacac catacttaaa gtaaattttc
    14281 gctacttcat ctttattgga acttgtataa gctacaccaa gttgccaaca ataatccgct
    14341 ttaattaagc tttcaggaag actgaacgaa ggtatattat tagatttcaa tagactaata
    14401 agttccaaca agatgttgta tgaatcatag cttttaggct tgtagtaaac ggatttccct
    14461 ttaaattcaa tcttaacgac tgtttgtttt tgggaatgac tgtctccaag tgaaaattca
    14521 acattactta aggactcagt aatattaaag catgacctta tttcagacaa atcttttaaa
    14581 aacctatcaa atagcaaaga gtatgattcc actaccaatc caacttctct attgatttgt
    14641 tttagcaaat atggatatct gtcaaaaaaa ttacttatcc cattttcttc ccttatctgc
    14701 tgtatatatt gttcatatgc ctttgacttg ttttcaattt ccttggaaaa atgatttata
    14761 tctagaacta gtgttttcat tgaaagaaac attatagttt caaataactg attttcaaac
    14821 tcactataaa ataacttatg tgtcttttcc cttaacaaat aaatattttc actaatagaa
    14881 gtatctaata tgtcatagtc aaaaattgag ttaacgtatt cgtaaaactg atggttctga
    14941 tattctaact ttaattcatc tctttttatc attttttcct accactactt aaaaatcctg
    15001 cctagactga gtctaaacag gaaattttta gtctgcttgt ccagattgtt ttaattaaca
    15061 acaaacaaat actgagttcg gacagtcatc agtaatagtt gcaaaccaac cggaaccttt
    15121 tttaccacca gctacttcca taagttcttt ttcagaaact tcttcgatag cattagtcaa
    15181 aatatccttt gaatttttca taaaactcat tctcctttct atcagtatgt agtgactatt
    15241 ttctacactt ttattgtaaa taatacgtct tcattttcaa tgagtaaaaa gtgcaaaaat
    15301 gacttttttc atatttttta gtaagatttt tgagatgtca cataagaggt cactttataa
    15361 caaatagccc tctgatataa aaaacaaaac tcgttcttta cagctatttt acaatctaat
    15421 cgcttctcgt tataacatca atctctaatc agaaaatggt tactttactt atttaatcag
    15481 gtcaggagtt tgaatgacag aagtcaaata tctgaaaaag gatgttaaat aaaactttca
    15541 aaacccattt ccatcaacta aaaacactta taacccgatc ttacaactaa tggattacca
    15601 tcaacagcaa ataatactat gcttgaaaaa tgtcaacatc atctactttt tgtgactata
    15661 attcagtaaa cgaacatgac gtgtaaaaat gtattaaaaa agtatctcaa aatcattcaa
    15721 tcacttgagt ttctgctact tttttatacc agtaggcact cttcttagga taacgctctt
    15781 gagtttcaaa atcgacatag aagagaccgt aacgtttttc atagccattt gaccatgaaa
    15841 agacatccat taatgaccac atgaagtatc ctttaacatt tacaccatca gaaatagcat
    15901 cagaaataac ttctaagtgt tttttcacat aatcgatacg tccatcatca tagacagtat
    15961 tatctacaaa ctcatctttg taaccaagac cattttcagt gatataaatt ttcttgtagt
    16021 taggataatc agctttaaca cgcatgattt gatcatataa gccttgtggg aagataatcc
    16081 aatcccagtc cgtttttgga acatcaacgg gagcttttct tcgaccaaca cccttgattt
    16141 ggtatttaga gctgcctttt tcccctttac cattatgaat gatttcagtc tcaccatcaa
    16201 aggcttgcat ccaatcactc atataatagt taataccaag gaagtcattc aaatcttttg
    16261 cagcgtctag tgcagcaaaa tcttcctcac gaagatcaag ttcaccacca ttcacttcaa
    16321 ggatatggtt aacaccttcc attgttttat ctgaatactt accaagataa gttgcatcaa
    16381 ggataaattt attatggatg atatcttcaa gttcagctgc tctaacatca tcaggattgt
    16441 tagcgtcaaa tggatactta gttggaagag catggacaac accaatttca cctgaatagc
    16501 caccattttt aaagagtttc acagcgcgag catgagaaac catcatgtta tgatgtgatt
    16561 ggaaaacttt agcaagatca tattggatac ctggagggaa tttaccaacc aagtattggc
    16621 catcaccaat aggcccaatt tcgttaaatg ttgtccaata gttaacttct gcgaattctt
    16681 taaaacaaaa ttctgcataa tttacaaaat gttcaatgtt ctcacgattg aggaaatcac
    16741 catccgagtg gagagcttct ggtgtatcaa aatggtgaag tgtaacaaaa ggctcaacat
    16801 gacgcttatg acactctgca aagagattgt ggtagtattc aactccttta gggttaactt
    16861 ctccttttcc tgttggaaaa atacgagacc aggcaataga gatacggatg ccgttgacac
    16921 caaattcttc actaagtttc aaatcgacag ggtaacgatt ataaaaatca cttgctggct
    16981 cagctgtgta ccaatagttg tcttctaagt atttatccca agctactggt cctttaccat
    17041 ctgtgtgggt agcgccttca gcctggtaag cagctgtagc accaccaaaa ataaaatctt
    17101 taggtaatgt tttagtcatc tcagtttctc cttgaatatc tttcaaaaat aaagttccca
    17161 aaacaatttt tgtgtttgag aactttacga catttaaact gttttcttaa ttttcaaact
    17221 gtgcttttac aaaatcaaga gctccttgac catcacgggt caatttgatg tattgagccc
    17281 cttctgtttt agctaattta atatcaagtt tatcagtttc cactttcata tcttcatagt
    17341 tagaagctac ttgaggtgca aggataacaa gttgatattg tggtaaaatc tcacggtgag
    17401 caccataact tcctgctgct gcagtgacag gtgcaccata ttctttagct gctttattca
    17461 aagcatttgc tagtagtcca cttgtaccac caccggcaca aagaacgaga acattagttt
    17521 gatcagtgat ttctttggtt tctttagctg ctgatttttc aagaatagca tcagcttttt
    17581 tagtatcaaa gtttgctgct actttttctt tgagggcatc tgatgaattc gtacctgctg
    17641 cttcttcagc aagaatttgc tcatcataaa ttttcaagaa tgggtagtag ataatcacat
    17701 caacaacgat taacaaagct gccaaaatga atgctagcac ttggaagttt gtcccaagga
    17761 taagacccaa tggagctggt gttgtccaag gtaagtttgc agtgaaactg ttcattccaa
    17821 gtgtgtcaat gaagaatttg aaaatccata cgttgacaat cggtgccaag ataaatggaa
    17881 taaagaaaat tgggttcaaa acaagtgggg caccgaacaa gataggttcg ttaactccaa
    17941 agaaagtagg aacaacagat gcacgtccaa tggctttgtt acgttttgat tttgttaacc
    18001 acatgaacat gaatggaacg acgagagttg caccagtacc acccatggta acgatgaaca
    18061 tttgagtccc tgaagtcaag atcttatcag catgttcacc agcttgaagt aattgaaggt
    18121 tggtttcagc atttgcgtaa gtaatcgctg caatggctgg ttcaacaata gaaggtccat
    18181 gaataccaac aaaccagaag aaagcaaatg caccgaagat aatagtgatt ccaacataac
    18241 catctgctgc ttggaacaat ggtgcaagaa gtttaccaat tgactcggca acgttaacgc
    18301 ctaaagtact atgaacaatc aattcaatca cataaagcag tacaactgat aatgtaaatg
    18361 gaatcaaatc cttaaatact tgagagatat ttggtggcac ctcttctggc atgcgaatag
    18421 taacattgtt ttttacacag actttataga catttacggt aataaaagct gcgatgaagg
    18481 ctgtcaacaa accttttgtt cccataaatc cagttaagaa accaccttct tttgctggat
    18541 tggctgccat aagtaaaaaa cctacaatag cagcgagcat ggtagacatg aagttgattt
    18601 ggtttgtgct tggtaatgat cgattcattg aatcggttaa tgctttggct gtcgtaccag
    18661 ccacaaacaa acctaaaata cccattgagt agttgtatgg cgtcatcaag agattctcaa
    18721 tatccttact ccaatggaag ccccatgcat ttggaacata ggcaatcaag ataaagatac
    18781 ttgaaaacaa gataacaggc ataccagcga tgaaaccatc acgaatagca cgaagataga
    18841 tgttacgaga tattttctcg aagaaaggtt tccctttctc aatctgagca attaatccat
    18901 tcattatttt gctcctctct tataaagttc aatcatgtgt ttcattaaat cttgtaataa
    18961 aatggtcgtc attaaatgat cttgaccatg cattaaagtg acactataag ctaagtcatc
    19021 tccagctgct tctttttgta atagacttgt ctgagcgtta tgagcatcat tcaagcagtc
    19081 actacctgca gcgattaatt cttctgcttt agcataatct ccttcttgcg ctgctttaag
    19141 cgcttccaaa aattttgaac gggcatcacc agcataggct acgatttcaa aacctaaaag
    19201 agtagtttct tctctattca ttgtagtttc ctccgaaaat aatgttacat tttttcagtc
    19261 caaggacttg cagttttatc tagtactttg tttaattcgt caatattttt gaaaccttct
    19321 gtacgcaacc attcacgagc tgcttgtggt ccttcttcga tatagacttt tacagaacct
    19381 gcccaggtag cacgtccaca taagacaccg ttgaatttag cacctgattc tgctgcaaac
    19441 accaaagtat cttggaacaa tttggcagaa acaccagcac tcaaataaat gtatggtaaa
    19501 tcagtagaag cttcttggtc acggaaagct tgagctgctt cttcttttgt aaagagaacc
    19561 tcaccatctg caaagccttc tacaaatttc atatttactg gaacttcaac tttcaacacg
    19621 tcaactccaa agcgctcttt tgagaaaact ttcattgctt cgttaacttt atgagcttta
    19681 acttttgcaa actcagggct agcattgtca gagattttct catcataagt tagaatttct
    19741 aagtagaatg gaatatcttc tgcacggcat tcagaaccaa tacgttcaat gtaagctttt
    19801 ttctgctcgt tgatatcttg atctccatca atatcatagt aaagaaggaa tttaactgct
    19861 tctgctccag cttctttaat acgttttgca gaccaaacat ctaagcaatc aggtaagcga
    19921 ctagttgttg ttgcatcgta tcctgttttc tcatatgcta acaacaagcc tgcttcttct
    19981 gaacgaacac gacttgctgg caagccatat tcaggatcaa gtagaattga ggatgcaaat
    20041 ggtgttagtt cttcagaaac taaactttta agctcttcaa tttgttctac tgttggctct
    20101 tttgtttgat gttgagccat catacgtttg agagctccac gttggtcaaa agctaaggca
    20161 gaaataacac catctacact tagtttttcc atgcttttac gtttgttttc agttaaagta
    20221 attgtcattt tttatacctc tttgatttta atagattgat ataacttatc gtaatttgcc
    20281 atgttaacat gcccagttgt tttttcttgc gcatttaaca tccctaagac atttgctttt
    20341 gttaataaag ctcgatcatc ttcatcattc gctaaacctg aagcaatacc tgccactgta
    20401 gaatcccctg aacctacagc gcttacaatt ttaattttag gaatgtcaac gttataaaac
    20461 gtatccttgt gctttgcaaa tacaccatca gcaccgagag aaacgattat ccattcaatt
    20521 ccatcaaata acttatcttg taagacttct tttaaggcat caaaatctct tgtcatttct
    20581 ttacctagaa gttgagaaag ttcttcaaga ttaggcttga taactgttgg tttactatca
    20641 ccttttagta ctgcttctaa agcatttcca gaacaatcta gaacagtctt cttaccatta
    20701 agattggcaa taccgattaa cttctgatag taatcatctg gcataccagc aggcagactg
    20761 cctgagagcg tcactacgtc aacatcattc agtaaatact taaaatgatg agtaaatcca
    20821 tcaatttcat ctacacttaa catcggtcct ttttctaaaa tctccgtttg attaccttcg
    20881 tgtaaaatgg ctatacaagt tctagtatca cctgaaattt tatagaagct taaaatcgaa
    20941 tcaggaagat gattaatgat aaaatcaccg ctttctccac ctatacaacc agtagctttg
    21001 actgtttcac cgaattcatt aagaactcgg gaaacattca agcctttacc accgggtgtc
    21061 tttgtaacgt ctacaactcg attgacagta tcgcatttta gctcatccaa agggtaggag
    21121 acgtcaatag ctggatttaa agtaactgtt aaaatcacaa tagctccttt ttctatatat
    21181 ccttatcata attctttcaa atattagtcg tgatattcac cacggtccca tttttctaga
    21241 aattcatcaa agaagtgtgg gttgttttga tcttggctag catgttgcaa gctatccatt
    21301 ttttcaatcc attttttatt ttcttcagtt ggtttgtatt ccgcggctaa gaaagcatcg
    21361 ataatatcat tcatcaataa accaccgatg atttttccac caaaaccaat aacgtttgcg
    21421 tttagctctt cttttgagta gatagcagat gtcatatctc taacgagtgc tgaacgaatt
    21481 ccaggaactt tgtttacggc atttgtaata ccaacaccag taccacagat aacaacacct
    21541 agttctgctt caccacttgc tactgcttca ccaacttttt taccaaaaat tggatagtgt
    21601 gtgcgaacat tatcatacgt accacaatca ataactttat gaccttgtga ttttaggtaa
    21661 tccacaacag cgattttttc ataagtaaca atatggtcac aacctacagc aattttcatt
    21721 tttgttctcc ttgttttaac ctatttcaat caattagcac attttattaa gcatgtcgac
    21781 acgaacttga tgacgtccac catcatattt accttcgaca aagcctttga taatgttctt
    21841 tgcaattcct ggagcactaa tttcagaacc aagcgtgatg attcgagcat tgttgtgtcc
    21901 tcttgtcatg tatgctgaac gctcatctga tacttcagct gccaccattc ctttgatttt
    21961 agtagctacc atgaaagaac caacaccata tgcatcaatg acaataccta agttatcttc
    22021 ggatgcatta acttcttttg caacggctaa agttgtatct acaaagtcac gtacttcgtt
    22081 ttcactaaca tcaacgactt cgtgtttacc ttctttaagg taatctttga taacttcttt
    22141 aagttcttga cctgctttgt cagcaccgat aataattgcc attttatttc tcctatgatt
    22201 tagaataagt gaatgtggaa aacctacgta gatagttaat taacgatttg caacatcttt
    22261 tgaaataacg ctttcattat ttctatgacc taatcataca cccaccaaac ataaaagtca
    22321 acatattttg tttattttta taaaaaataa acaaaatatg tttatttttt tcatttttac
    22381 gttattatcc taatgtttct tgtgtttctt tttcatttca taaatccctt tgacagccac
    22441 tcgtaaccta tcatatatta cgaaaccctt atctctattt attgtaaacg ttttatttaa
    22501 aacattttct attttgttaa tttttgtttt ttccaatgtt tatatttgtt ttgtttgatt
    22561 tttttattga tattatgtta tgataccttt aatagttata ccctaagaca ctgataggag
    22621 ataagaatga aaaagaaaga gcgtcatgaa aaaattctcg atatcttaaa agttgacggt
    22681 tttataaaag taaaagatat tattgatgaa atgaacatct cagatatgac cgctagacga
    22741 gatctcgata cattggcaga taaaggatta cttatcagga cccatggtgg tgctcaatat
    22801 ttggattatt cttcagcaaa ggacgaaggt cacgagaaaa cacacactga aaagaaggtc
    22861 ttacagacta ccgaaaaaaa acaaattgca caaagagcta aaaacattat taaagatggc
    22921 gaaactgtct ttataggtcc agggacaaca ttagagcatc tagctgtcga attgaaaaat
    22981 agaaatatca gagttattac aaatagcctt cctgtttttt taattttgca cccgagcact
    23041 actattgatt tgattttaat tggtggtgaa tgtcgtgaaa ttactggagc ttttgttggt
    23101 gctattgcca ttaataatct agaatcacta actttttcaa aggcttttgt tagcgcaaat
    23161 gctgtttata ataattctat tgcaacgtac agtgacctcg aaggagaagt tcaaagagtt
    23221 ggattgaata atgctgttga gaaaatcctt ctagttgata gtaccaagtt tgaaagttat
    23281 gacttctata atttctacca actagatcaa gtggacttaa ttgtgactga taaaaatgtg
    23341 acaactgata tcatagaaaa gtacaagaaa ttctcaaaaa tcataatcgc tgacaagtaa
    23401 aggacctact catattaaaa agcacttcag ggtttagata tatcccctgt caagtaaaca
    23461 gggagcatat ctgaaagtag tgtttgtatt ataaagaagt ttcttgctaa cttattttct
    23521 ggtttttttc agacttatca gtcttgtact gttccttttt ctgatgaata acgtggaaat
    23581 aggcagacag ctatatattt cacctctaga atggttgcca ttactgtcat caagacatgc
    23641 ttgttcttta tcgtatggag taaagctttc ttttagccat caacatacct cttaagtaga
    23701 ttttggttcg ttaccatgtc tacttaagag gtgtcttcaa agcgctttaa aacgttgata
    23761 taacagtata ttaacgtttt gagaattgtg aagctttacg agctttttta agacctggtt
    23821 tttggttcac tccattattt aaagtcaaat ccctttaaaa tcaatgtttc taaaatgaaa
    23881 aatcactaaa aatcttattt atagacaaat atttaaacct aaacggtatc aaaaataagt
    23941 ttcggagctt atcaaataat gaaaatctgt ctcaattacc gagtctttt
//
LOCUS       DATTYN010000034        23197 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.34, whole genome shotgun sequence.
ACCESSION   DATTYN010000034 DATTYN010000000
VERSION     DATTYN010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23197
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.34"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(219..1532)
                     /locus_tag="VB649_001546"
     CDS             complement(219..1532)
                     /locus_tag="VB649_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEP1670488.1"
                     /translation="MTIIIMDSNSAHETDNLSVSFLNFCYNSLMKRHFLLLTFYLFLT
                     GLTAGLVAFILTKAIHLIQSLSFGFSQGSFSTMIASVPPQRRALSLLFAGLLAGLGWH
                     LLAKKGKDIQSIQQIIQDDISFSPWTQFWHGWLQLTTVSMGAPVGREGASREVAVTLT
                     SLWSQRCNLSKADQKLLLACASGAALGAVYNAPLATILFILEAILNRWSLKNIYAACL
                     TSYVAVETVALLQGRHEIQYLMPQQHWTLGTLIWSVLAGLILSLFAHAYKHLLEHLPK
                     ADAKSQWFIPKVLIAFNLIAGLSIFFPEILGNGKAGLLFFLHEEPHLSYISWLLVAKA
                     VAISLVFASGAKGGKIAPSMMLGGASGLLLAILSQYLIPLSLSNTLAIMVGATIFLGV
                     INKIPLAAPVFLVEITGQSLLMIIPLALANLIFYFSYQFYRFILK"
     gene            complement(1507..2466)
                     /gene="nrdF"
                     /locus_tag="VB649_001547"
     CDS             complement(1507..2466)
                     /gene="nrdF"
                     /locus_tag="VB649_001547"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEP1670489.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINDIYANGDALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFR
                     DWMYDLLYQLYENEEKYTKTLYDGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL"
     gene            complement(2799..4958)
                     /gene="nrdE"
                     /locus_tag="VB649_001548"
     CDS             complement(2799..4958)
                     /gene="nrdE"
                     /locus_tag="VB649_001548"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEP1670490.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVL
                     PNTMSFTSITEKIEYLISNDYIESAFIQKYRPEFITELDSIIKSENFRFKSFMAAYKF
                     YQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLDITNMYDELVANPKI
                     TKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPT
                     IKHGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLLNYWTLVESNNIAR
                     ERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQASDWEALRDAVQ
                     KDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYISAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(4978..5196)
                     /locus_tag="VB649_001549"
     CDS             complement(4978..5196)
                     /locus_tag="VB649_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin NrdH"
                     /protein_id="HEP1670491.1"
                     /translation="MITVYSKNNCMQCKMTKKFLEQHGANFQEINIDEHPEKVDYVKS
                     LGFTSAPVIEADNLVFSGFQPAKLKELI"
     gene            5589..5852
                     /locus_tag="VB649_001550"
     CDS             5589..5852
                     /locus_tag="VB649_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEP1670492.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTISAEGADAEDAIAAIEETMTKEGLA"
     gene            5857..7590
                     /gene="ptsP"
                     /locus_tag="VB649_001551"
     CDS             5857..7590
                     /gene="ptsP"
                     /locus_tag="VB649_001551"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEP1670493.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVADTNAEEARL
                     DVALQAAQDELSVIRENAVESLGEEAAAVFDAHLMVLADPEMISQVKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATINEESIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     VIAVNGITGEVIIDPSEDQVLAFKEAGAAYAKQKAEWSLLKDAHTETADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGDAMFRTQMRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAIFDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMEEYANRALTECSTAEEV
                     LELSKEYVSED"
     gene            7775..9202
                     /locus_tag="VB649_001552"
     CDS             7775..9202
                     /locus_tag="VB649_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEP1670494.1"
                     /translation="MAKQYKNLVNGEWKLSENEITIYAPATGEELGSVPAMTQAEVDA
                     VYASAKKALSDWRVLSYVERAAYLHKAADILVRDAEKIGAILSKEVAKGHKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPVNLA
                     GSKIAPALIAGNVVALKPPTQGSISGLLLAEAFAEAGIPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGEGIGKLAGMRPIMLELGGKDSAIVLEDADLVLAAKNIVAGA
                     FGYSGQRCTAVKRVLVMDKVADQLAAEIKTLVEKLSVGMPEDDADITPLIDTSAADFV
                     EGLIKDATDKGATALTAFNREGNLISPVLFDHVTTDMRLAWEEPFGPVLPIIRVTTVE
                     EAIKISNESEYGLQASIFTTNFPKAFGIAEQLEVGTVHLNNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTTVKSVVFDIQ"
     gene            9297..10571
                     /locus_tag="VB649_001553"
     CDS             9297..10571
                     /locus_tag="VB649_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEP1670495.1"
                     /translation="MKKLNVILVGLLSILMLSLAIVFINRWKLNEDSQRIVLAEKKKN
                     TSDLVIKAVKHIKKDQKDYYYFSPIKQADDFFVDNLPVSLYKKKNSDKELILVKPKLQ
                     SSHLRSVNTLTISKIVYQKKFFHLAKKSEKVISTYHVTDDLKPFQVKDLVSGHLERIQ
                     EEVEKKYPNAGFNSDKYNGLKESNSLLSDGFEVKSGNLIFDKKLTIPLTTLFDVINPD
                     FLANSDRAAYDNYRTYKEQHPKKLVALTFDDGPDPTTTPQVLDILAKYQAKGTFFMIG
                     SKVVNNENLTKRVSDAGHEIANHTWDHPNLTNLSVSEIQHQVNMTNQAIEKACGKKPR
                     YLRPPYGATNATVQQSSGLTQMLWTVDTRDWENHSTDGIMTNVKNQLQPGGVVLMHDI
                     HQTTINALPTVMEYLKAEGYECVTVSELYAHQ"
     gene            complement(10681..11766)
                     /locus_tag="VB649_001554"
     CDS             complement(10681..11766)
                     /locus_tag="VB649_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEP1670496.1"
                     /translation="MITKFPPQWQEKLDQVAFTHLTPIQEQAFQPIVDGKNFLGISPT
                     GTGKTLAYVFPSLLALTPKKSQQLLILAPNTELAGQIFEVTKDWAQPLGLTAQLFISG
                     TSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMSVNTIVLDEYDELLGDSQYDFV
                     QKISHYVPRDHQMVYMSATNKVDQTSLAPNTFCIDLSEQTNDAIQHFYLMVDKRERTD
                     LLRKFANIPHFRALVFFNSLSDLGATEERLQYNGAAAVSLASDINVKFRKTILEKFKS
                     HQLSLLLATDLVARGIDIDNLDYVIHFDVARDKENYTHRAGRTGRMGKSGIVITFVSH
                     PEDLKKLKKFAKVSEISLKNQQLHFIN"
     gene            11864..12490
                     /gene="udk"
                     /locus_tag="VB649_001555"
     CDS             11864..12490
                     /gene="udk"
                     /locus_tag="VB649_001555"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEP1670497.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILDSFPNARIAMIQHDSYYK
                     DQSHMSFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKKHTRSNTTFRQ
                     DPQDVIIVEGILVLEDERLRDLMDIKLFVDTDDDIRIIRRIKRDMMERGRSLESIIDQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDVINSKIASILGEV"
     gene            12570..12833
                     /locus_tag="VB649_001556"
     CDS             12570..12833
                     /locus_tag="VB649_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEP1670498.1"
                     /translation="MLLIWLGLLFVWNELVFVIYAFDKRKAIKKKRRISERKLLVITV
                     LFGGFGALLAAKKYHHKTRKWYFVITWYTSILLTLLVTYIFMK"
     gene            complement(12886..13695)
                     /locus_tag="VB649_001557"
     CDS             complement(12886..13695)
                     /locus_tag="VB649_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEP1670499.1"
                     /translation="MKQITQQKWLRYGLFIALVLNGIELELLGLTANNLSFKEAFALI
                     LTISLLGIYLIPFAAAIFYLSKKFHMNLNVIIVSCLSGLYISGFLASCGNHLVGQFWS
                     YIIPSKDALKLWGDALTAPIVEEPIKASSAILVITLFPRLTLKEKLVVALLSGMGFQL
                     AEDIRYLIQAKSIDSLVPTAIERISTAVTSHWVHTAIFTIGAYLLLKGSNLFSKQQQI
                     FWLLSPLVLHFIWNSPLTSIPGMTVLLGTLILLIFGDLFQKINTLDDDVLF"
     gene            13840..14337
                     /locus_tag="VB649_001558"
     CDS             13840..14337
                     /locus_tag="VB649_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEP1670500.1"
                     /translation="MNKSKKIEQYQLMIAQAKELFANESNALANLSNASALLNMTLPN
                     SVFAGFYLFDGQELILGPFQGRVSCVHIKLGKGVCGESAQSRRTIIINDVKQHANYIS
                     CDAAAMSEIVVPMVKEGHLIGVLDLDSSLVADYDEVDQEYLEAFVDLFLEKTTFTFNM
                     FGVKN"
     gene            14337..16007
                     /gene="dnaX"
                     /locus_tag="VB649_001559"
     CDS             14337..16007
                     /gene="dnaX"
                     /locus_tag="VB649_001559"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEP1670501.1"
                     /translation="MYQALYRKYRSQTFDEMVGQSVISTTLKQAVESGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVDGEPCNQCDICRDITNGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKAIKQKAIREHLAWVLDKEGIAYEVDALNLIARRAEGGMRDALS
                     ILDQALSLSPDNQVTIAIAEEITGSISMLALGDYVRYVSQEQATQALAALETIYDSGK
                     SMSRFATDLLTYLRDLLVVKAGGDNQRQSAVFDTNLSLSIDRIFQMITVVTSHLPEIK
                     KGTHPRIYAEMMTIQLAQKEQILSQANLSGELISEIETLKNELAQLKQQLSQLQSRPD
                     SLARSDKTKPKTASYRVDRVTILKIMEETVRNSQQSRQYLDALKNAWNEILDNISAQD
                     RALLMGSEPVLANSENAILAFEAAFNAEQVMSRNNLNDMFGNIMSKAAGFSPNILAVP
                     RTDFQHIRKEFAQQMKSQKDSVQEEQEVALDIPEGFDFLLDKINTIDD"
     gene            16102..16305
                     /locus_tag="VB649_001560"
     CDS             16102..16305
                     /locus_tag="VB649_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEP1670502.1"
                     /translation="MTIRQFLFMAFVCAFETYFFNDLLLSGNYLFALFWGLLLFRDLR
                     RVYTINQLTKTILKTANSPKKKD"
     gene            complement(16280..17221)
                     /locus_tag="VB649_001561"
     CDS             complement(16280..17221)
                     /locus_tag="VB649_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEP1670503.1"
                     /translation="MKTSEKIYQLLSQTDDFVSGEYLADQLSISRTSVWKSIKSLENQ
                     GIQIDSLKHKGYRMVQGDILLPKTISQGLGMPVTYTPHSQSTQLDAKQGIEAHNSAPR
                     LYLAPSQEAAKGRLDRQFFSASTGGIYMSMYLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTEIKWVNDIYLGNHKVAGILTEAITSVETGLITDVIIGVGLNFFVTDFPEAIA
                     QKAGSLFTEKPTITRNDLIIDIWKLFLSIPVKDHVKVYKEKSLVLNKQVTFIENSQEK
                     RAIAIDLTDQGHLIVQFENGDLQTLRSGEISLSSWEN"
     gene            17425..19791
                     /locus_tag="VB649_001562"
     CDS             17425..19791
                     /locus_tag="VB649_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEP1670504.1"
                     /translation="MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTS
                     NKIKPIKKSKKINKTHKGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIF
                     YADLKGSPFEYLIPKGASLAKPAVAQQAASQGTSKVADPHHHYEFNPADIVAEDALGY
                     TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSPVSTVTANGIPGLHFPTSDGFQ
                     FNGQGIVGVTKASILVNHDGHLHPISFADLRQGGWAHVADQYDPAKKAETHHTPELSE
                     REKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIP
                     DPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDALTPFPSNEKDPNMMKEWL
                     ATVIKLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGV
                     TDYRFLDNMPQLEGIDISQNNLKDISFLSKYKNLTLVAAADNGIEDIRPLGQLPNLKF
                     LVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLSRNADVDLATL
                     QAPNLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQ
                     IKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVT
                     NIDISHNNIPLADLKLNEQHIPEAIAKNFPAVYEGSMVGNGTAEEKAAMATKAKESAQ
                     EASESHDYNHNHAYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD"
     gene            20328..21524
                     /locus_tag="VB649_001563"
     CDS             20328..21524
                     /locus_tag="VB649_001563"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEP1670505.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYIDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSG
                     DIAQGVNEALESREGDTDDLSHIGAGDQGLMFGFAINETPELMPLPISLSHQLVRRLA
                     ELRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEATNDQIRQDVIEKV
                     IKAVIPADYLDDDTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLATKAEVQLAYAIGVAQPVSVRVDTFGTSTVPE
                     AVLEAAVRQVFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWERLNKVDALVE
                     AVKTVL"
     gene            21698..22957
                     /locus_tag="VB649_001564"
     CDS             21698..22957
                     /locus_tag="VB649_001564"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEP1670506.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGV
                     PAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
                     DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQ
                     GVQKLHGTRHQVIPDRIEAGTYIALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMT
                     VEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADGRGTIIDTIYEKRIN
                     HVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLMAEGKTEITN
                     IEFILRGYASIIAKLTALGADIQLIED"
BASE COUNT         7388 a         4053 c         4842 g         6914 t
ORIGIN      
        1 catttttaca ggctgctctt cctcaaggat gagttttaca gcagagagtt tgaaggcttt
       61 atcaaaggtt tttcttggca taatgacttt tcctcgtttc cacttaattt tgtgtctact
      121 ttattatacc aagtccaact ttgcttaaaa tataatgtcc aacttttggg gtgcagttca
      181 ttcatccgaa gctttttatt aaaaaagtaa ttaactaatc atttaaggat gaaacgataa
      241 aactgatagc taaaataaaa aatgaggtta gctaatgcta aagggataat cattagtaac
      301 gattggcctg taatttcaac cagaaaaact ggtgccgcca agggtatctt attgatcaca
      361 cctaaaaaga ttgttgcacc aaccataatg gctaacgtat ttgatagaga caagggaata
      421 aggtactgac taaggatagc tagtagtaag ccactagcac ctccaagcat catagaagga
      481 gcaattttac ccccttttgc tccagaagca aaaactaaag agatagcgac agctttggca
      541 acaagtagcc agctaatata gctcagatgt ggttcttcat ggagaaaaaa gagtaatcca
      601 gctttgccat ttcctaaaat ctctgggaag aaaatgctga gtcctgcgat aaggttaaaa
      661 gcgatgagaa ctttcggaat aaaccactga cttttggcat cagccttagg aaggtgttcc
      721 agaagatgtt tgtaagcgtg agcaaagagg gaaaggataa gaccagccag gacggaccaa
      781 ataagggttc ctagcgtcca atgttgctga ggcattaggt attgaatctc atgtcggcct
      841 tgtaataaag caactgtttc cacagccaca tagctcgtta ggcaggcagc gtatatattt
      901 ttaagggacc aacggttaag aatagcttct aagataaata aaatagtggc taagggagca
      961 ttgtagacag caccaagggc agcgccagaa gcgcaggcta ataaaagttt ttgatcggct
     1021 tttgacaagt tgcatctttg gctccaaaga gacgtcaagg taacagcgac ttcccttgaa
     1081 gctccttctc ggccgacagg agctcccata gatacggtcg ttaattggag ccaaccatgc
     1141 caaaactgtg tccagggact aaatgagatg tcatcttgaa tgatttgctg aatagattga
     1201 atgtcctttc cttttttagc caataggtgc cacccaagac ctgcaagaag tccagcaaag
     1261 aggagtgaaa gagctcgtct ttgtggtgga acactagcaa tcatagtgct aaaagaacct
     1321 tgactgaatc caaaactgag ggactgaatc aggtgaatgg cttttgttaa gataaaagca
     1381 acaaggccag ctgttaaacc tgttaaaaag aggtaaaagg tcaagagtaa aaagtgtcgt
     1441 ttcataagac tattataaca aaagttaaga aaagagactg atagattatc agtctcgtga
     1501 gcactattag agtccataat tataatcgtc atcagacata gcttctacag aaccaagaag
     1561 atagccattc cctacctgtg agaaaaagtc atggtttgat gttcctgttg aaataccatt
     1621 cataacaatt gggttaacat cgtttgcagt atctgggaat aaaggatctt gtcctaaatt
     1681 cataagagct ttgttagcat tgtagcgtaa aaaggtcata acttcttcag tccaccctac
     1741 gccatcataa agcgttttgg tgtatttttc ttcattttca tatagctgat aaaggaggtc
     1801 atacatccaa tcacgaaaat tctcttgctc atcttctggt agttcgttaa aaccaagctg
     1861 gaatttgtaa ccgatataag taccatgtac agattcatca cgaataatta gtttaatgat
     1921 ttcagcaaca tttgctagct tattatttcc caaatagtaa agaggggtga aaaagccaga
     1981 ataaaaaaga aaagtttcga gatatgttga ggcaactttc ttttgtaagg catctccatt
     2041 agcgtaaatg tcattgataa tacgtgcttt ttcttgaaga aactcattat tattagtcca
     2101 ctcaaagatc tcttcaattt cttttttggt gtttaaggtt gaaaagatag acgaataaga
     2161 tttagcgtga acagattcca tgaattgaat attgtttaag acagcttctt cgtgaggagt
     2221 gcgaacatca gcacgaatag cttcgacacc agtttctgat tgcatggtat caagtagggt
     2281 taatcctcca aaaactttgc caacaagatc tttttcttga agagaaagtt tgcgccaatc
     2341 gtctaagtca tttgataaag ggatacgggt atcaagccaa aattgttcgg tcaacttttc
     2401 ccaagttgac ttgtcaatga cgtcttcgat ttcattccag ttaattgctt cataatatgt
     2461 agtcatagaa aaatgatctc ctaaagagta gtaaagtgcg ttaaggatat cgagataaac
     2521 cagtagaacc gaccaaagtt ctaccggtaa taataagttt aaatagattc aaaagggtaa
     2581 cgaatgagtt agtgagtggt ttaggcggaa cgcctaaagc gattgcccaa gaagtaatag
     2641 atgctttagc atcattaggg catatcgagg aattacgaca cggagtaagg aaagtcgata
     2701 atactttcct tacgtagtta gtgagtggtt taggcagatc gcctaaagcg actgccgtag
     2761 aagtaataga tgctttagca tcattacttc ttaaccaatt aaatgacaca agattcacat
     2821 tggtttgcgc ccacttcttc cccatcatcc gtaaaggtac ggatatagta gatagattta
     2881 atgcctttat tgaaagcgta gtttcgtaag atggataaat cacgagtggt ttgtttgctt
     2941 tgtgttttcc actcataaag ctccataggc aactcactac gaaggaatag agttaatgac
     3001 aagccttggt ccacatgttc ggtcgcagcg gcatagacat caataacttt gcgcatgtcc
     3061 atatcgtaag cagatatata gtaaggaatg gtatccgtag acaaaccatt tgcaggatag
     3121 tagattttac caattttctt ttcttgacgc tcttcgatgc gttgtgtgat tgggtgaata
     3181 gaagcagagc agtcattgat ataagaaata gagccatttg gagcaactgc tagacggttt
     3241 tgatgataaa gaccatcttt ttgaacggcg tcgcgaagag cctcccaatc agaagcttgc
     3301 ggaataaaat ggtctttaaa gagacttttg accaaatcag attttggaac aaagtgtcct
     3361 gtaacgtatt tatcaaagta actaccatta gcgtacttag agttctcaaa gccaacaaag
     3421 gtagtttggc gctcacgagc gatgttattg gattcgacca aggtccaata attcaggagc
     3481 ataaagtaaa tatcagtaaa ctcgatggat tctggactgc catattcaat atgatgttga
     3541 gcaaggtaag aatgtagtcc catagctcca aggccaaaag tatgagcttg gctattgcca
     3601 tgtttaatgg ttggaacagc ttcaatgctt gatgaatcag taacaaaagt tagggcacgt
     3661 gtcatggtct taatagaacg gccaaagtct ggtgaggtca tcatgttcag gatattagtg
     3721 gaacctaagt tacatgaaat atcagttccc atttctacaa actcttgcgc atcattgata
     3781 aggctaggtg tttgaacttg taaaatttca gaacacaagt tgctcatgat gatttttcca
     3841 tcgataggat tagctttatt agctgtatca atattgatga tataagggta accagattct
     3901 tgttgtaatt ttgaaatctc tgtttcaaga tcacgagctt taattttagt cttagtaatt
     3961 ttagggttcg ccactaactc atcgtacata ttggtaatgt cgagatagtt aaagggaatg
     4021 ccatattctt tttcaacatt gtaaggacta aagagataca tgtcctcgtt tttacgagct
     4081 aattcgtaga atttatcagg aacggtaatc cctagtgaca aggttttaac acgcaccttt
     4141 tcatcggcat tttctttttt agtagataag aaagcaatga tatcaggatg aaaaacattt
     4201 aggtaaacaa caccagctcc ttgacgttgc ccaagttgat ttgaataaga aaaactatct
     4261 tcaaataatt tcataacagg aacaactcct gaggctgcac cagcatagcc tttgattggt
     4321 gcgccagctt cacggaggtt agacaaggta atcccaacac ctccaccaat acgggataat
     4381 tgcaaggcag agttaatgga acgtccgata gaattcatgt catcagttac ttgaatcaag
     4441 aaacaagaga ccaattcacc acgacggctt cgaccagcat ttaaaaagga aggagtagcc
     4501 ggttggtaac gttggttaat catttcaacg gctaaatctt ttgctaagtc ttcttgacca
     4561 tctgcaaaat acaaagcatt aaacaagaca cggtcttcaa ggttttctaa ataatgctct
     4621 ccatcatttg tttttaaggc gtattgctgg tagaacttgt aggctgccat aaatgattta
     4681 aagcgaaaat tttctgattt gattatgcta tctaattcag taataaattc aggacggtat
     4741 ttctgaataa aagctgattc aatgtaatca tttgagatta aatactcaat tttttccgta
     4801 atggaagtaa aagacatggt gtttggcagc acattttcag cgaaaaaagc ttttaaagct
     4861 tctttgtctt tatgaagtgg aattttacca ttaacaggac ggttaatttc attatttagg
     4921 cgaaaatatg aaatatcgcc aagatctttg agactcatat tatttttcct tgtcttatta
     4981 aatcaattct tttaactttg caggttggaa gccagaaaat acgaggttat ctgcttcgat
     5041 aacaggagca gatgtgaagc caagactttt cacataatcc actttttcag gatgttcatc
     5101 gatattaatt tcctggaagt tggctccgtg ttgttctaaa aatttcttag tcattttgca
     5161 ctgcatgcaa ttatttttgg aatatactgt aatcatgtct tgtccttcta aaattagtaa
     5221 tggttccatc ttaaatggaa ttactataat agcatataaa aaataaagct aaaaagcaag
     5281 ctataaactt atctgaaaca caacatattg tgttgaaata aaaaacagaa acctaaatat
     5341 tgtgtcaatc tggattctta tggttagagc tctagcgttt tggtgataga agctaagcag
     5401 ttttaataaa gcattaaagt ctgaaaaata aattgtgaaa aacgtgaaaa taaaagaaaa
     5461 taatttcaca ttttttgtcg tttaaatatt taatcttgaa aataaaaaag cattgtgcta
     5521 taatcggttg ttgtaagggt tatcatgtga tggctcaaaa atacacaact taaaaggaga
     5581 accatactat ggcttcaaaa gactttcaca ttgttgcaga aacaggtatt catgcgcgtc
     5641 cagcgacttt gcttgttcaa acagctagca aatttgcttc agacatcact cttgactaca
     5701 aaggtaaagc agtaaatcta aaatcaatca tgggtgttat gagtcttggt gttggtcaag
     5761 gtgcagatgt tactatctca gctgaaggtg cagatgctga agatgccatt gcagcaattg
     5821 aagaaacaat gactaaagag ggattggcat aagactatga cagaaatgct taaaggaatt
     5881 gcagcctcag acggcgttgc tgttgctaaa gcatatctac tagttcagcc ggatttgtca
     5941 tttgagactg ttacagtcgc agatacaaat gcagaagaag ctcgccttga tgttgcactc
     6001 caagctgcac aagacgagct ttctgttatc cgtgaaaatg cagtagaaag cttaggtgaa
     6061 gaagcagcag ccgtttttga tgcccatttg atggttcttg ctgatccaga aatgatcagc
     6121 caggttaaag aaacgattcg cgcaaaacaa acgaatgcag aaacaggtct taaagaagtg
     6181 actgacatgt tcatcaccat ctttgaaggc atggaagata acccatacat gcaagaacgt
     6241 gcagcggaca tccgcgacgt tgcaaaacgt gtgttggctc accttttagg tgtaaaactt
     6301 ccaaatccag ctacaatcaa tgaagaatca atcgttatcg cacacgattt gacaccttca
     6361 gatactgctc aacttaacaa acaatttgta aaagcatttg ttacaaatat cggtggtcgt
     6421 acaagtcact cagctatcat ggcacgtaca cttgagatcg ctgcggtact tggaacaaat
     6481 gatattacaa aacgtgttaa agatggtgat gtgattgccg ttaatggtat cactggtgaa
     6541 gtgattatcg atccaagcga agatcaagta cttgctttta aagaagctgg tgcggcttat
     6601 gccaaacaaa aagcagagtg gtctctcctt aaagatgcgc atactgaaac agctgatggc
     6661 aaacactttg aattggctgc taatatcggt acgcctaaag acgtcgaagg tgttaatgac
     6721 aatggcgctg aagctgttgg cctttaccgt actgagttct tgtacatgga ttctcaagac
     6781 ttcccaactg aagacgaaca atacgaagct tacaaggcag tgcttgaagg catgaatggc
     6841 aaacctgttg tggttcgtac gatggatatt ggtggcgaca aggaacttcc ttactttgac
     6901 cttccaaaag aaatgaatcc attccttggt ttccgtgcac ttcgtatttc catctctgaa
     6961 actggggatg ccatgttccg cacacaaatg cgtgcgcttc ttcgtgcctc tgttcacgga
     7021 caacttcgta ttatgttccc aatggttgcg cttcttaaag aattccgtgc tgcaaaagca
     7081 atctttgatg aagaaaaagc aaacttgctt gcagaaggcg ttgcggttgc tgatgacatc
     7141 caagttggta tcatgattga gattcctgca gctgctatgc ttgcagacca atttgctaag
     7201 gaagttgatt tcttctcaat tggaacaaac gaccttatcc aatacactat ggcagcagac
     7261 cgtatgaacg aacaagtatc atacctttac caaccataca acccatcaat attacgtttg
     7321 atcaacaatg tgatcaaagc agcgcacgct gaaggtaaat gggcaggtat gtgtggtgag
     7381 atggcaggtg accaacaagc tgttccactt cttgtcggaa tgggcttgga tgagttttct
     7441 atgtcagcaa cttcagtact tcgtacgcgt agtttaatga agaaacttga ctctgctaag
     7501 atggaagaat atgcaaatcg tgcgcttaca gaatgttcaa cagcagaaga agttcttgaa
     7561 ctttctaaag aatacgtttc tgaagattaa agggttaaag agttggttta aaccagctct
     7621 tttttgctag ctaaaaatac aattactttt tggtgtgaaa tcatttgagt tatcaaataa
     7681 ttatcagaat tttcagatat ttagcgtagc caaatcttga attatatcgg aaaagtgata
     7741 gaataagatt actaccataa aaggagataa aacgttggca aaacaatata aaaatttagt
     7801 gaacggtgaa tggaaactat cagaaaacga gattaccatt tacgcaccag caacaggtga
     7861 agagttagga tcagttccag cgatgacgca ggcagaggta gatgctgttt acgcttcagc
     7921 taaaaaggct ctatcagatt ggcgcgtctt gtcttatgtg gaacgtgcag cttaccttca
     7981 taaagcggct gatattttag tacgtgatgc tgaaaagatc ggcgcgattc tttcaaaaga
     8041 agtagccaaa ggtcacaagg cagctgtcag tgaagttatt cgtaccgctg aaatcattaa
     8101 ttatgcagca gaagaagggc ttcgtatgga aggtgaagtt cttgaaggtg gtagcttcga
     8161 agccgcaagt aagaagaaga ttgctattgt tcgtcgtgaa ccagttggtt tagttcttgc
     8221 catctcacct tttaattatc ccgttaactt ggcaggttct aaaattgctc cagcccttat
     8281 tgcaggaaat gttgttgctc ttaaaccacc aacacaaggc tctatttctg gtttgttact
     8341 agcagaagct tttgcagaag ctggtattcc agcaggtgtc tttaatacca ttacagggcg
     8401 aggttctgtt atcggtgatt acatcgttga gcacgaagcg gttaacttta tcaactttac
     8461 aggttctact ccaattgggg aaggaatcgg taaattagcg ggtatgcgac caattatgct
     8521 tgagcttggc ggtaaggatt ctgctatcgt tttggaagat gcagatcttg ttttagcagc
     8581 gaaaaatatt gtagccggtg cttttggtta ctcaggacaa cgttgtacag cggttaaacg
     8641 cgttcttgtg atggacaagg tggcggatca attggcggct gagattaaaa cacttgttga
     8701 aaaactaagt gtcggaatgc ctgaagacga tgctgatatt acaccattaa ttgatacatc
     8761 agctgctgat tttgttgaag ggttgattaa agatgcaact gataagggag ctactgcttt
     8821 gacagccttt aatcgtgaag gcaatcttat ttcacccgtt ctctttgatc atgtgacaac
     8881 tgacatgcgt ttggcatggg aagagccgtt cggcccagta ttaccaatta ttcgtgtaac
     8941 cactgtagaa gaagccatca agatttctaa tgagtctgaa tatggtttgc aagcttctat
     9001 ttttacaact aatttcccaa aagcttttgg cattgctgag caattagaag ttggaactgt
     9061 tcaccttaac aataaaacac aacgtggaac agataatttc ccattcttag gcgctaaaaa
     9121 atcaggtgca ggggtacaag gagttaaata ttctatcgaa gctatgacaa ctgttaaatc
     9181 tgttgtattt gatatccagt aataaaaaaa ataaacaaaa agttaggtta acttaacttt
     9241 ttgtttattt ttttaatgtt ttttgttaca atagtctata cagatggagg caactattga
     9301 aaaaattaaa tgttattctt gttggtttat taagcattct gatgttgagt ttagctattg
     9361 tgtttattaa tcgttggaaa ctaaacgaag atagtcagcg tatagttttg gctgaaaaga
     9421 aaaaaaacac gtcagattta gtgatcaaag ctgtaaaaca tattaaaaaa gatcaaaaag
     9481 actattatta tttttccccg ataaaacaag cagatgattt ttttgtagat aatttacctg
     9541 tttcattata caaaaaaaag aattcagata aagaattgat tttagtaaag cctaaactgc
     9601 aatcttctca cctaagatca gttaacactt tgactatttc taaaatagtt tatcagaaaa
     9661 aattttttca tttggctaaa aaatcagaaa aagttataag tacatatcac gttacagacg
     9721 acttgaaacc gtttcaggta aaggatctag tatcaggaca tttagaaaga atacaagaag
     9781 aagttgaaaa aaaatatcca aatgctggtt ttaatagcga taagtacaat ggcttaaaag
     9841 aatctaattc tttattaagc gatggctttg aggtaaaatc gggaaacctt atttttgata
     9901 aaaagctaac gatacctttg acgacattat ttgatgttat taatccagat tttttagcaa
     9961 atagcgatag agctgcgtat gataattata ggacctacaa agaacagcat cccaaaaaac
    10021 tagttgcatt aacgtttgat gatggtccag atccgacgac gactcctcaa gttttagata
    10081 ttttggcaaa ataccaggct aagggaactt tctttatgat aggttcaaaa gttgtgaata
    10141 atgaaaacct tactaaacgt gttagcgacg ctggccatga aattgctaat catacttggg
    10201 atcatcccaa tctgactaat ctttcagtca gcgagattca acatcaagtt aatatgacga
    10261 accaggctat tgaaaaagct tgtggcaaga aacctcgcta tttacgccct ccatacggag
    10321 ctacaaatgc aactgttcag caatcctcag gattaacaca gatgctttgg acggttgata
    10381 caagagattg ggaaaatcat agcactgatg gcattatgac taatgtcaaa aaccaattgc
    10441 aaccgggagg agttgtttta atgcatgata ttcatcaaac aactatcaat gctttgccga
    10501 cagttatgga atatctaaaa gcagaaggat acgaatgtgt gactgtatca gaactctatg
    10561 cgcatcagta agtaatatcg ttatgtttct ttagaattga tatactaaac aatccaatta
    10621 ctttgaagta attggattgt tgtttttagt agcccttgat taagttttgt tttttaacaa
    10681 ctagttgatg aaatgaagtt gttgattttt gagggagatt tcagagactt tagcaaattt
    10741 tttcaatttt ttgaggtctt cagggtggct aacaaaggta ataacgatac cagattttcc
    10801 catacggccg gttcgtccag ctctgtgagt ataattttcc ttatcacgag caacatcaaa
    10861 atgaatgaca tagtcaagat tatcaatatc aatgccccga gcaacaagat ccgtagctaa
    10921 caataaggag agttggtggg atttgaattt ttcgagaatg gttttacgga atttgacatt
    10981 gatgtcactc gctaaggaaa ccgcagcagc tccattatat tggagacgtt cttccgtagc
    11041 acccaaatca gataaactgt tgaaaaagac taaggctcta aaatgaggaa tattagcaaa
    11101 ttttcgtaat aaatcggtac gttcgcgctt gtcaaccatg aggtaaaaat gctgaatagc
    11161 atcgttggtt tgctctgaaa gatcgatgca gaatgtattt ggagctaagg aagtttgatc
    11221 caccttatta gtagcactca tgtataccat ttgatgatct cgaggaacat agtggctaat
    11281 tttttgaaca aaatcatatt gggaatcacc taataattcg tcatattcat ctaaaacaat
    11341 ggtgttgaca gacatcatct tgattttttt caatttaatg agttcaaaaa tgcgtccagg
    11401 ggttccaatc aggatttcag gacctttttt gaggcgttcg atttgacgtt tttgactggt
    11461 tccagaaata aagagttgtg ccgttaagcc tagtggctgt gcccaatcct ttgtgacttc
    11521 aaaaatttgg ccagctaatt cggtattagg ggctaaaatg agtagttgtt gggacttttt
    11581 aggcgtcagt gccaatagac taggaaagac ataagctaag gtcttgcccg tcccagtagg
    11641 gctaatacca aggaaatttt taccatcaac aataggttga aaggcctgtt cttggattgg
    11701 cgttaaatgg gtaaatgcaa cttggtcaag tttttcttgc cattgagggg gaaatttagt
    11761 gatcatgcgt cttcctttta ctattgtttc tatattcatt atagcattat agtctcaatt
    11821 ttggtaaaat agtgagaaag actttttaga tttggagttt aaaatgctta aaaaaccgat
    11881 tattattggt gtaactggtg gttcaggtgg cggtaaaaca agtgtgtcac gcgctatttt
    11941 ggacagtttt ccaaatgctc gtattgcaat gattcaacac gattcttact ataaagatca
    12001 gtctcacatg agttttgaag aaagggtcaa aaccaattat gaccatcctc tagcttttga
    12061 tacagatttt atgattcagc aactaaaaga attattagct ggtagacctg tagatattcc
    12121 tatctatgat tacaaaaagc atacccgcag taatacgacc tttcgtcagg atcctcagga
    12181 tgttattatt gttgaaggta ttcttgtcct agaagatgag cgtttgcgag atttgatgga
    12241 tatcaagctc tttgtagaca cagatgacga tattcgtatt attcgtcgta ttaagcgtga
    12301 catgatggaa cgtggcagaa gcttagaaag tattattgat cagtacacaa gcgtggtaaa
    12361 gcctatgtat catcagttta ttgagccaag taaacgctat gctgatattg ttattccaga
    12421 gggagttagt aatgtcgttg ctattgatgt tattaatagt aaaattgcga gtattcttgg
    12481 agaagtatag tggaagtggc tgagtagatt atttaaatct gctcttttat tgttgtgctc
    12541 ttcatagaga aagggatcat aaaatagaaa tgttattaat ttggcttgga ttactatttg
    12601 tttggaatga actcgtgttt gtcatatatg cctttgataa aagaaaagcc ataaaaaaga
    12661 aacggcgtat tagtgaaaga aaattattag tgataacagt tttgtttgga ggttttggag
    12721 cattacttgc agctaaaaag taccaccata aaaccagaaa gtggtacttt gtcatcactt
    12781 ggtatactag tattttgttg acattactag taacttatat ctttatgaag tgagtcactt
    12841 aaaagaccct taatcagtat tatttagtca aggctctttt atagtttaaa aaagcacatc
    12901 atcgtcaagg gtgttgattt tttgaaaaag atcaccgaag attaaaagga ttaatgttcc
    12961 tagtaaaact gtcatgccag gaatgcttgt tagaggagag ttccagatga aatgtagcac
    13021 cagaggactt aataaccaga aaatttgttg ctgttttgaa aaaaggttag aaccctttaa
    13081 taataagtat gctccaatgg taaaaatagc tgtatgtacc caatgtgaag tcacagcagt
    13141 gctaatacgt tcaatagcag tcggtacgag actatctata gattttgctt gaatcaaata
    13201 acggatatct tctgctagtt gaaagcccat gccagaaagt aaagcaacaa ctaatttttc
    13261 tttaagagta agtctaggaa ataaagtaat tactaaaata gccgaagaag ccttaatggg
    13321 ctcttcgaca ataggggcag ttaaagcatc tccccaaagc tttaaagcgt ctttagaagg
    13381 gatgatgtat gaccaaaatt gtcctacgag atggttccca caagaagcta aaaaacctga
    13441 aatataaagt ccgctaagac agctaacaat aataacattc aggttcatat gaaatttttt
    13501 acttaaataa aaaatagctg ctgcaaatgg aattaagtaa atgcctaata gactaatggt
    13561 tagtattaga gcaaaagctt ctttaaagga aaggttgtta gctgtcagtc ctaacaattc
    13621 aagttcaata ccatttaaaa ctaaagcaat aaaaagaccg tatcgtaacc atttctgttg
    13681 agtgatttgt ttcacgaaaa cctcctaata ttaagatgat attaataata ttgaaaatta
    13741 tatcataaac aacctcaaaa accattttaa aaactgactg aagcgaaaga tagtcgtaaa
    13801 aaatactcga atagacccag atatgctata ataaaaggta tgaataagtc taaaaaaatt
    13861 gagcaatacc aactaatgat agcacaggca aaagagctgt ttgcgaatga atcaaatgct
    13921 ttggctaatt tgtcaaatgc cagcgccctg ttaaacatga cactacccaa ttctgttttt
    13981 gcgggatttt acctttttga tgggcaggaa ttaattcttg gcccttttca aggtagggtt
    14041 tcttgcgtcc atatcaagct tggtaaaggt gtttgtggcg aatcagctca gtctcgtcga
    14101 accattatta taaatgatgt gaagcagcat gccaactata tttcctgtga tgcggcagcc
    14161 atgagtgaaa ttgttgtgcc tatggtgaaa gaaggccatt tgattggggt gctggacttg
    14221 gattctagcc ttgtagctga ttatgatgag gttgatcaag aatacttaga ggcctttgtg
    14281 gacctatttc ttgaaaagac cacgtttacc tttaacatgt ttggagttaa aaactgatgt
    14341 atcaagctct ttatcggaaa taccggagcc aaacgtttga cgaaatggtg ggacaatcgg
    14401 ttatttccac aactttaaag caggcagttg aatctggcaa gattagccat gcttatcttt
    14461 tttcaggtcc tagagggact gggaaaacaa gtgcggcaaa gatttttgca aaggccatga
    14521 attgtcctaa ccaagtcgat ggtgaaccct gtaatcaatg cgatatttgc cgagatatca
    14581 cgaatggaag cttggaagat gtgattgaaa ttgatgctgc ctcgaataat ggtgttgatg
    14641 aaattcgtga cattcgagac aaatcaacct atgcgccaag tcgtgcgact tacaaggttt
    14701 atattattga tgaggttcac atgttatcaa caggggcttt taatgcgctt ttgaaaactt
    14761 tggaagaacc gacagaaaat gttgtcttta tcttggcaac aacggaattg cataaaattc
    14821 cagccactat tttatctcgt gtgcaacgct ttgaattcaa agctattaag caaaaagcta
    14881 ttcgagagca tttagcctgg gttttggaca aagaaggtat tgcctatgag gtggatgctt
    14941 taaatctcat tgcaaggcga gcagaaggag gcatgcgtga tgctttatct attttagatc
    15001 aggctttgag cttgtcacca gataatcagg tcaccattgc aattgccgaa gaaattacag
    15061 gttctatttc catgcttgct ctgggtgact atgttcgata tgtctcccaa gaacaggcta
    15121 cgcaagctct ggcagcctta gagaccattt atgatagtgg gaagagcatg agccgctttg
    15181 cgacagattt attgacctat ctgcgtgatt tattggtggt taaagctggc ggcgacaatc
    15241 agcgtcagtc agctgttttt gataccaatt tgtctctctc gatagatcgt atattccaaa
    15301 tgataacagt tgttactagt catctccctg aaatcaaaaa gggaacccat cctcggattt
    15361 atgccgaaat gatgaccatc caattagctc agaaagagca gattttgtcc caagcaaact
    15421 tgtcaggaga gttaatctca gagattgaaa cgctcaaaaa tgagttggca caacttaaac
    15481 aacaattgtc gcagctccaa tcgcgtcctg attcactggc aagatctgat aaaacgaaac
    15541 ctaaaaccgc aagctacagg gttgatcggg ttaccatttt gaaaatcatg gaagaaacgg
    15601 ttcgaaatag ccaacaatct cgacaatatc tagatgctct aaaaaatgct tggaatgaaa
    15661 ttctagataa catttctgcc caagacagag ccttattgat gggctctgag cctgtcttag
    15721 caaatagtga gaatgcgatt ttggctttcg aggctgcctt taatgcagaa caagtcatga
    15781 gccgaaataa tcttaatgat atgtttggta acattatgag taaagctgct ggtttttctc
    15841 ccaatattct ggcagtacca aggacagatt ttcagcatat tcgtaaggaa tttgctcagc
    15901 aaatgaaatc gcaaaaagac agtgttcaag aagaacaaga agtagcgctt gatattccag
    15961 aagggtttga ttttttgctc gataaaataa atactattga cgactaaaac tgaaatacat
    16021 aagggtaagg ttttgccctt acccacgttt tatctcgtta cttttcttca tagtacagta
    16081 tttttttgtt ataataaagc tatgactatt cgacaatttc tttttatggc ctttgtatgt
    16141 gcctttgaaa cctatttttt taatgacctg ttgctctctg gaaattatct cttcgcctta
    16201 ttttggggct tgttgctctt tagggattta agaagagtgt ataccattaa ccaattgact
    16261 aaaaccattt taaaaacggc taattctccc aagaagaaag actgatttca ccgcttcgca
    16321 aggtttgaag gtcaccattt tcaaactgta caatgaggtg tccttgatct gtgagatcaa
    16381 tcgcgatagc acgtttttct tgactatttt ctataaaggt cacttgttta ttaagaacaa
    16441 gtgatttttc tttgtaaact ttgacatggt ccttgacagg aatagataag aataatttcc
    16501 agatgtcaat gataaggtca ttgcgcgtga tagtcggttt ttcggtaaag agagaacctg
    16561 ccttttgagc aatcgcttct gggaagtcgg tgacaaaaaa gttgagacca accccaataa
    16621 tgacatcggt gattaaacca gtttcaacag aagtaatggc ttctgtcaga atccctgcaa
    16681 ctttatggtt acctagatag atgtcgttta cccatttgat ttctgtatca atgcctgtta
    16741 atcgcgagat agctttgaca atactggaag caaccatcat cgtataagga ggcatatcag
    16801 cataagggac attgggtttt aggtacatgg acatgtaaat accaccggtg ctagctgaaa
    16861 aaaattgccg atcgaggcgt cctttggcag cttcttggct aggagctagg taaagccttg
    16921 gagcgctgtt atgagcttcg attccttgtt tggcatctaa ttgggtagat tggctgtgag
    16981 gggtataggt gactggcatc ccaagccctt ggctaatggt tttgggtaat aaaatatcac
    17041 cttgtaccat gcggtagccc ttgtgtttta aagaatcaat ttgaatcccc tgattttcga
    17101 gacttttgat ggatttccaa acggatgtac gagagatact gagttgatct gctagatatt
    17161 ccccactgac gaagtcatcg gtttgtgaca gtaattgata aattttttct gatgttttca
    17221 tatgtatagt atattataaa agatcttatt ttcaaaggaa aagacaagtt agtttttttg
    17281 tgtaatgcta ctaacaacag aaactattgt ttgttgaagc ttcagagctc caactcgtca
    17341 acaactaata gttatcctaa aaagagcttg aggaaaaaca agtgatgcga tatacttaac
    17401 cagttaaata aaaaggaggg ttgaatgaaa acgaaaaaag ttattatttt agttggtcta
    17461 ttgttatcat ctcagttgac tttgatagct tgtcaatcac gaggtaatgg tacatatccc
    17521 attaaaacga aacaatcacg taagggaatg acgtcaaaca aaattaaacc gattaaaaaa
    17581 agcaaaaaga taaacaagac tcacaaaggt gtggcgggtg tcgattttcc tacagatgat
    17641 gggtttattt taaccaaaga ctcaaaaatc ttatcaaaaa cagatcaggg aatcgttgtt
    17701 gaccatgatg gacattcgca ttttattttt tatgccgatt taaagggaag tccatttgaa
    17761 taccttattc caaaaggagc aagtttagct aagccagctg ttgctcagca agcagctagt
    17821 caagggactt ctaaagtagc agatcctcat caccattatg aatttaaccc agcagatatt
    17881 gtggctgaag atgctttagg ctacacggtt cgccacgatg atcacttcca ttatattttg
    17941 aagtcaagct tatcaggtca gacacaggca caagctaaac aggttgctac tcgcttgcca
    18001 caaaccagta gccctgtttc aacagttaca gctaatggta ttccaggctt gcatttccca
    18061 acctcagatg gttttcaatt taacggtcaa ggtattgttg gggtaacaaa agccagtatt
    18121 ttagtgaacc acgatggtca cttacatcct atttcttttg cggaccttcg tcagggtggc
    18181 tgggcacatg tggcagatca atacgatccc gctaaaaaag cagaaaccca tcacacacca
    18241 gagctatctg aacgtgaaaa ggaataccaa gaaaaattag cttatttggc agaaaaattg
    18301 gggattgatc catcaactat taaacgtgtg gaaacacaag acggtaaact tggtttggaa
    18361 taccctcacc atgaccacgc acacgtattg atgttatctg atattgaaat cggaaaagac
    18421 attccagatc cacatgctat tgagcatgcc cgtgaattgg aaaaacataa ggttggaatg
    18481 gataccttgc gtgccttagg gtttgatgaa gaagtgattt tggatatcgt tcgcactcac
    18541 gatgctctaa ccccattccc atcaaatgaa aaagatccga atatgatgaa agaatggtta
    18601 gcaacggtta tcaaacttga cttgggcagc cgtaaagatc ctttgcaacg taaaggactt
    18661 tcactgttac ccaacttaga aactttagga attggcttta caccaatcaa agatatctca
    18721 cctgttttgc aatttaaaaa attgaaacag ttgttaatga caaaaacagg ggtgactgat
    18781 tatagatttt tggataatat gccacagtta gaaggcattg atatttcaca aaacaatctc
    18841 aaagatatta gtttcttgag caaatataaa aacttaaccc tagtagcggc tgctgataat
    18901 ggtattgaag atattaggcc gcttggtcaa ttaccaaatc tcaaattcct cgtattgagt
    18961 aacaataaga tttctgattt aagcccattg gcatcgttac atcaattgca agaattgcac
    19021 attgataata atcagattac agatttaagc cctgtttctc ataaagaatc attgacggtt
    19081 gttgatttat caagaaatgc tgatgttgac ttagcaacac ttcaagcacc caacttagaa
    19141 acgttaatgg tcaatgatac caaggtttct catttggatt tcttgaaaaa taatcctaat
    19201 ctatctagcc tatctattaa ccgtgcgcaa ttgcaatctc ttgaaggtat tgaagcaagt
    19261 agcgtcattg tcagagtaga agcagaaggt aaccaaatta aatcgcttgt gcttaaagac
    19321 aagcaagggt cacttacttt cttggatgtg acaggcaacc agttgacttc tctagaaggt
    19381 gttaataatt ttacagcact tgacatttta agcgtgtcta aaaaccaatt aacaaatgtc
    19441 aacctatcta aacccaataa gacagttact aacattgata ttagtcataa caatatccca
    19501 ttagcagacc ttaaattgaa cgagcaacat attccagaag ccattgcgaa aaacttccca
    19561 gcggtttacg aaggttctat ggtaggtaat ggaacagctg aagaaaaagc agctatggct
    19621 actaaggcga aagaaagtgc tcaagaagca tcggaatcac atgactacaa ccataatcat
    19681 gcctatgaag atgaagaagg tcatgctcac gagcacagag acaaagatga tcacgaccat
    19741 gaacatgagg atgaaaatga agctaaagat gagcaaaacc atgctgacta aactaatcta
    19801 agaataaccc tatccaactg aatcgtccta atgacaccat tgttgactat caagaaaacc
    19861 tcaagaataa ccttgaggtt tttttgaaat aaataggata atgagtgaaa agaatggcac
    19921 ctaaatggct aaaacatgtt ataatagatt gttattgagt cccgataaga cggtctgttg
    19981 aacgaaatgt ttttgagacg ttgttgactt catttgggga acagtcgttc tccctttaga
    20041 taaattactt cgtctaaggc ttattttgtg gtgacatcct ctcaacaagg agaccggatt
    20101 ctttgtaact caacgctatt gtcagacatt ctttgtctgg ttaatggacg ctagccacta
    20161 ggtggactag ctagttgcct tactagtaaa accgtaactg attagctaag ttggttttgg
    20221 ccacttgact tgctcaatca gctaggaaga aaggggtagg caacttcttg ctttgtggtc
    20281 aatgtgactg aaaaaggaag aatcaacata ttagggggga catttttatg tcagaacgta
    20341 aacttttcac gtctgagtcc gtatctgaag ggcatccaga taagattgca gaccaaattt
    20401 cagatgctat tttagatgcc attttagcag aagatccaga agcccatgtg gctgcagaaa
    20461 cttgtgttta cacaggttct gttcatgttt ttggagaaat ctcaacaaca gcatacattg
    20521 atattaaccg tgtggtccgc gacaccattg cagaaattgg ttatacagaa gcagaatatg
    20581 gcttttcagc agaatcagtg ggagtacatc catcacttgt agaacaatct ggagatatcg
    20641 ctcagggggt taatgaagct ctcgaaagca gagaaggtga tactgatgac cttagccata
    20701 ttggagcggg tgaccaaggg ctcatgtttg gttttgccat caatgaaaca ccagaattga
    20761 tgcctttacc aatttcctta tctcaccaat tagtgcgtcg cttggcggaa ttacgtaagt
    20821 caggtgagat tagttatcta cgtccagatg ctaaatctca agtgacagtt gagtacgatg
    20881 aacacgataa acctgttcgt gtggatacag tcgttatttc tactcagcat gatccagaag
    20941 ctactaatga ccaaattcgt caggatgtga ttgaaaaagt gatcaaggct gtaattccag
    21001 cagattattt agatgatgac acaaagttct tcattaatcc aacaggacgt tttgttattg
    21061 gaggtccgca aggagactct ggattgaccg gacgtaagat tattgtggat acctatggag
    21121 gctattcacg tcatggtggc ggtgcttttt caggaaaaga tgcgacaaaa gtggaccgtt
    21181 cggcttctta cgctgctcgt tatattgcta aaaaccttgt ggcagcaggc cttgcgacca
    21241 aagctgaagt ccaactagct tatgcgattg gggtggctca gcctgtgtct gttcgcgtgg
    21301 atacatttgg aacctcaacg gttcctgaag ctgttttaga agctgctgtt cgtcaagtct
    21361 ttgatttacg gccagcaggc attattcaaa tgcttgattt aaaacgcccg atttacaaac
    21421 aaacagctgc ctatggtcac atggggagaa cagatattga tttgccatgg gagcgtttaa
    21481 ataaggttga tgctttagta gaagctgtaa aaacagtatt ataaacgaca actttattaa
    21541 aaaagtagag tgagtgaaaa aatcttactc tgcttttttg ttattaaata agcctttaaa
    21601 agggatgatt aaaaattaag acgtcaataa ttgtcaggct tcatgattta tgataaaatg
    21661 aaaaggttga attctagtat aagaaagttt tgaatgtatg cgtaaaatta ttattaatgg
    21721 cggaaaagcc ttatctggag aagtggcagt ttcaggggca aaaaacagtg ttgttgcgct
    21781 tattccagca atcatcttag ccgatgatat tgtgattctt gatggtgtac ctgctattag
    21841 tgatgtagat agtctgattg aaatcatgga gcttatggga gcaacagtaa actatcatgg
    21901 tgatacttta gaaattgacc ctagaggggt gcaagacatc ccgatgcctt acggaaagat
    21961 taatagtctt cgagcttcct attatttcta cggtagtctt ttaggtcgtt ttggacaagc
    22021 agttgttggc ttacctggtg gttgcgattt aggaccaaga ccaattgact tgcatttgaa
    22081 ggccttcgag gctatgggag ttgaagtgtc ttatgagggt gaaaatatga atttatcgac
    22141 aaatggtcaa aaaattcatg gcgctcatat ctatatggac accgttagtg tcggtgctac
    22201 aattaatact atggttgcgg caacaaaagc tcaaggtaaa acggttattg aaaacgctgc
    22261 acgcgagcca gagattattg atgtggctac tcttttgaat aacatgggtg cgcatattcg
    22321 tggagcaggt acagatatta ttacgataca aggtgttcag aaattgcatg gtactagaca
    22381 ccaagttatt cctgatcgta ttgaagcagg gacttatatc gctttggcgg cagctattgg
    22441 aaaaggtgtt aagatcacta atgttcttta tgagcattta gagagtttca ttgctaagtt
    22501 agaagaaatg ggtgtccgta tgacggtaga agaggatgct atctttgttg aaaagcaaga
    22561 atccctcaag gctattacaa ttaaaacatc tccttaccct ggctttgcca ctgatttgca
    22621 acagccatta acgcccttgt tgttaaaagc agatggtcgt ggaacgatta ttgacactat
    22681 atatgaaaag cgcattaacc atgtgccaga gttgatgcgc atgggagcag atatctcagt
    22741 tattggtggt cagattgttt atcaagggcc gtctcgcctg acaggagctc aggtcaaagc
    22801 cactgattta cgtgccggag cggctctagt gactgctggt ctaatggctg aaggcaagac
    22861 agaaattact aatattgaat ttatcttacg tggctatgct agtatcattg caaaattaac
    22921 agcactaggg gcagatattc aattaatcga agactaaaga gaagctaacg cttctctttt
    22981 tttggtactc tgacctcatg gaagaatttc tttggctgat aagttgatga agaataagca
    23041 gaggttgtgc tggttctttt tagaaaagaa tgccccaaca gaagtggcag tttgctgaag
    23101 aggtttggta aaagaaatcg ctaacgcgtc atttttactc ataagcgttt aattgtctga
    23161 tgattagtac taaagacgca ttggttatca gatgatt
//
LOCUS       DATTYN010000035        21024 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.35, whole genome shotgun sequence.
ACCESSION   DATTYN010000035 DATTYN010000000
VERSION     DATTYN010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21024
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.35"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(28..99)
                     /locus_tag="VB649_001565"
     tRNA            complement(28..99)
                     /locus_tag="VB649_001565"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(64..66),aa:Glu,seq:ttc)
     gene            complement(295..1069)
                     /locus_tag="VB649_001566"
                     /pseudo
     CDS             complement(295..1069)
                     /locus_tag="VB649_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            1234..1307
                     /locus_tag="VB649_001567"
     tRNA            1234..1307
                     /locus_tag="VB649_001567"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Arg,seq:tct)
     gene            complement(1464..1943)
                     /gene="rlmH"
                     /locus_tag="VB649_001568"
     CDS             complement(1464..1943)
                     /gene="rlmH"
                     /locus_tag="VB649_001568"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEP1670507.1"
                     /translation="MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTP
                     DKASFADNQLIMSKEAQRIHKKIGERDFVIALAIEGKQFPSETFSELISGVTVKGYAT
                     ITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITKGSPYHK"
     gene            2154..3377
                     /locus_tag="VB649_001569"
     CDS             2154..3377
                     /locus_tag="VB649_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEP1670508.1"
                     /translation="MPSMKHILKSLSILLIGFLGGLIAIITFNNLYPHSPSKINSGKA
                     TTSNMVFNNTTNTTKAVKAVQNAVVSVINYQDNPSSSLSNPYTKLFGEGRSKENKDAE
                     LSIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
                     VVKISSDKIKTVAEFADSTKLNVGEVAIAIGSPLGTQYANSVTQGIVSSLSRTVTLKN
                     ENGETVSTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSNGNSGAVEGI
                     GFAIPSTDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALSQINIPTSVTGGIVVA
                     EVKEGMPASGKLAQYDVITEIDGKTVNSISDLQSSLYGHDINDTIKVTFYRGTTKKKA
                     DIKLTKTTQDLTKTQ"
     gene            3436..4242
                     /locus_tag="VB649_001570"
     CDS             3436..4242
                     /locus_tag="VB649_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEP1670509.1"
                     /translation="MFLILSRNSLMTKELLIDLPIEDIVTNPYQPRIQFNQRELQDLA
                     TSIKSNGLIQPIIVRKSDIFGYELVAGERRLKASKMAGLKKVPAIIKKISTLESMQQA
                     IVENLQRSNLNAIEEAKAYQLLVEKKHMTHDEIAKYMGKSRPYISNTLRLLQLPTPII
                     KAIEEGKISAGHARALLTLSDDKQQLYLTHKIQNEGLSVRQIEQLVTSTPSSKLSKKT
                     KNIFATSLEKQLAKSLGLSVNMKLTANHSGYLQISFSNDDELNRIINKLK"
     gene            4475..5830
                     /gene="dnaA"
                     /locus_tag="VB649_001571"
     CDS             4475..5830
                     /gene="dnaA"
                     /locus_tag="VB649_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEP1670510.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLLKVDKHIATI
                     YLDQMKELFWEKNLKDVILTAGFEVYNAQISVDYVFEEDLMIEQNQTKINQKPKQQAL
                     NSLPTVTSDLNSKYSFENFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTH
                     LLNAIGNSVLLENPNARIKYITAENFINEFVIHIRLDTMDELKEKFRNLDLLLIDDIQ
                     SLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNI
                     TPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQI
                     DTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQNIVLAR
                     QVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMISQDESLRIEIETIKNKI
                     K"
     gene            5985..7121
                     /gene="dnaN"
                     /locus_tag="VB649_001572"
     CDS             5985..7121
                     /gene="dnaN"
                     /locus_tag="VB649_001572"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEP1670511.1"
                     /translation="MIQFSINRTLFIHALNATKRAISTKNAIPILSSIKIEVTSTGVT
                     LTGSNGQISIENTIPVSNENAGLLITSPGAILLEASFFINIISSLPDISINVKEIEQH
                     QVVLTSGKSEITLKGKDVDQYPRLQEVSTENPLILKTKLLKSIIAETAFAASLQESRP
                     ILTGVHIVLSNHKDFKAVATDSHRMSQRLITLDNTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSPSQILFRSEHISFYTRLLEGNYPDTDRLLMTEFETEVVFNTQSLRHAME
                     RAFLISNATQNGTVKLEITQNHISAHVNSPEVGKVNEDLDIVSQSGSDLTISFNPTYL
                     IESLKAIKSETVKIHFLSPVRPFTLTPGDEEESFIQLITPVRTN"
     gene            7196..7393
                     /locus_tag="VB649_001573"
     CDS             7196..7393
                     /locus_tag="VB649_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEP1670512.1"
                     /translation="MYQIGSFVEMKKPHACVIKETGKKANQWKVLRVGADIKIQCTNC
                     QHVIMMSRYDFERKLKKVLQP"
     gene            7723..8838
                     /gene="ychF"
                     /locus_tag="VB649_001574"
     CDS             7723..8838
                     /gene="ychF"
                     /locus_tag="VB649_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEP1670513.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASRGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTEDEAKVVKGLFLLTTKPVLYVANVDEDKV
                     ANPDGIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDKEEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            8908..9477
                     /locus_tag="VB649_001575"
     CDS             8908..9477
                     /locus_tag="VB649_001575"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEP1670514.1"
                     /translation="MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIIKNLDVTFTDDKNF
                     KAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKL
                     RLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVINHVMGQFNTEDNIAI
                     SLTLDRVVNAVKFYLQENDFEKTMQKFNG"
     gene            9480..12983
                     /gene="mfd"
                     /locus_tag="VB649_001576"
     CDS             9480..12983
                     /gene="mfd"
                     /locus_tag="VB649_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEP1670515.1"
                     /translation="MNILELFSQNKKVQSWHSGLTTLGRQLVMGLSGSSKALAIASAY
                     LDDQKKIVVVTSTQNEVEKLASDLSSLLDEELVFQFFADDVAAAEFIFASMDKALSRI
                     ETLQFLRNPKSQGVLIVSLSGLRTLLPNPDVFTKSQIQLTVGEDYDSDTLTKQLMTIG
                     YQKVSQVISPGEFSRRGDILDIYEITQELPYRLEFFGDDIDSIRQFHPETQKSFEQLE
                     GISINPASDLIFEASDFQRGIEQLEKALQTAQDDKKSYLEDVLAVSKNGFKHKDIRKF
                     QSLFYEKEWSLLDYIPKGTPIFFDDFQKLVDKNARFDLEIANLLTEDLQQGKALSNLN
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDQMHQLTQYAMQEFFNQFPLLIDEIKRY
                     QKNQTTVIVQVESQYAYERLEKSFQDYQFRLPLVSANQIVSRESQIVIGAISSGFYFA
                     DEKLALITEHEIYHKKIKRRARRSNISNAERLKDYNELAVGDYVVHNVHGIGRFLGIE
                     TIQIQGIHRDYVTIQYQNSDRISLPIDQISSLSKYVSADGKEPKINKLNDGRFQKTKQ
                     KVARQVEDIADDLLKLYAERSQQKGFSFSPDDDLQRAFDDDFAFVETEDQLRSIKEIK
                     ADMESMQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVAVLVPTTVLAQQHYENFKA
                     RFENYPVEVDVLSRFRSKKEQAETLERIRKGQIDIIIGTHRLLSKDVVFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLVREAIIREMDRGGQIFYVYNKVDTIEKKVAELQELVPEASIGFVHGQM
                     SEIQLENTLIDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYRPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFEMYSQLLEQAIASKQGKTTVRQKGNTEINLQIDAYLPDDYIADERQK
                     IDIYKRIREIQSREDYLNLQDELMDRFGEYPDQVAYLLEIALLKHYMDNAFAELVERK
                     NNQVIVRFEVTSLTYFLTQDYFEALSKTHLKAKISEHQGKIDIVFDVRHQKDYRILEE
                     LMLFGERLSEIKIRKNNSVFK"
     gene            13145..13417
                     /locus_tag="VB649_001577"
     CDS             13145..13417
                     /locus_tag="VB649_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEP1670516.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTNIKLN
                     DHIEISFGNKLLTVRVIEIKDSTKKEDALKMYEIISETRITLNEEA"
     gene            13404..13775
                     /locus_tag="VB649_001578"
     CDS             13404..13775
                     /locus_tag="VB649_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEP1670517.1"
                     /translation="MKKPSIVQLNNHYIKKENLKKKFEEEESQKRNRFMGWILVSMMF
                     LFILPTYNLVKSYVDFEKQNQQVVKLKKEYNELSKSTKKEKQLAERLKDDNFVKKYAR
                     AKYYLSREGEMIYPIPGLLPK"
     gene            13910..15196
                     /locus_tag="VB649_001579"
     CDS             13910..15196
                     /locus_tag="VB649_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEP1670518.1"
                     /translation="MRKLLAAMLMTFFLTPLPVISTEKKLIFSKNAVYQLKQDVVQST
                     QFYNQIPSNPNLYQETCAYKDSDLTLPAGRLGVNQPLLIKSLVLNKESLPVFELADGT
                     YVEANRQLIYDDIVLNQVDIDSYFWTQKKLRLYSAPYVLGTQTIPSSFSFAQKVHATQ
                     MAQTNHGTYYLIDDKGWASQEDLVQFDNRMLKVQEMLLQKYNNPNYSIFVKQLNTQTS
                     AGINADKKMYAASISKLAPLYIVQKQLQKKKLAENKTLTYTKDVNHFYGDYDPLGSGK
                     ISKIADNKDYRVEDLLKAVAQQSDNVATNILGYYLCHQYDKAFRSEIKALSGIDWDME
                     QRLLTSRSAANMMEAIYHQKGQIISYLSNTEFDQQRITKNITVPVAHKIGDAYDYKHD
                     VAIVYGNTPFILSIFTNKSTYEDITAIADDVYGILK"
     gene            15193..16479
                     /gene="tilS"
                     /locus_tag="VB649_001580"
     CDS             15193..16479
                     /gene="tilS"
                     /locus_tag="VB649_001580"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEP1670519.1"
                     /translation="MMTYQEIFNEIKNKAYFKNHRHVLIAVSGGVDSMNLLHFLYLFQ
                     DKLKIRIGIAHVNHKQRSESDSEEAYLKCWAKKHDIPIYVSNFEGIFSEKAARDWRYA
                     FFKSIMLKNNFSALVTAHHSDDQAETILMRLIRGSRLRHLSGIKSVQPFANGQLIRPF
                     LTFSKKDFPEIFHFEDSSNRELSFLRNRVRNNYLPLLKQENPRFIQGLNQLALENSLL
                     FQAFKELTNHITTTDLTEFNEQSKSIQYFLLQDYLEGFPDLDLKKSQFTQLLQIIQTA
                     KQGYYYLKKDYYIFIDKFSFKITKIVPKTELVKDEKMLEYDSNLCYRDYCFSFMPKSN
                     EDQGQVSIPLFSLSSIKLRSRQSGDYISFGHFSKKIRRLFIDEKFTIAERQNAIIGEQ
                     DEQIIFVLIGNKTYLRKACKHDIMLAKLYIDKLEKG"
     gene            16484..17026
                     /gene="hpt"
                     /locus_tag="VB649_001581"
     CDS             16484..17026
                     /gene="hpt"
                     /locus_tag="VB649_001581"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEP1670520.1"
                     /translation="MLEQDIQKILYSENDIIRKTKKLGEQLTKDYQEKNPLMIGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYHGGTSSSGEVKILKDVDTNIEGRDIIIVEDII
                     DTGRTLKYLRDMFKYRKANTIKIATLFDKPEGRVVKIEADYVCYNIPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            17048..19027
                     /gene="ftsH"
                     /locus_tag="VB649_001582"
     CDS             17048..19027
                     /gene="ftsH"
                     /locus_tag="VB649_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEP1670521.1"
                     /translation="MKNNKNNGFVKNSFIYILMIIVVITGFQFYLKGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIIEVKGKYEKPQKVTVNSGLSFLGGRASTQVTEFSSL
                     VLPSDTILKEMTAAADKNGTELTVKQESSSGTWITFLMSFLPIVIFAAFMMMMMNQGG
                     GGARGAMSFGKNKAKSQSKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKSLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNENIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLANDVNLKVVAQQTPGFV
                     GADLENVLNEAALVAARRNKIKIDASDIDEAEDRVIAGPSKKDRTISQKEREMVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDLKEQLAGLMGGR
                     VAEEIVFNAQTSGASNDFEQATQIARAMVTEYGMSEKLGPVQYEGNHAMMPGQISPEK
                     AYSAQTAQMIDDEVRELLNQARNQAADIINENRDTHKLIAEALLKYETLDAAQIKSIY
                     ETGKMPVDLETDDNEAHALSYDEIKNKMTESESAE"
     gene            19353..20744
                     /locus_tag="VB649_001583"
     CDS             19353..20744
                     /locus_tag="VB649_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEP1670522.1"
                     /translation="MTIFRKKKKYSNKTEMQRHFKVIDLVFLGLGSMVGTGIFTVTGI
                     GAAKYAGPALTISIIISAIAIGILALFYAEFASRMPSNGGAYSYVYATLGEFPAWLVG
                     WYIIMEFLTAISSVAVGWGSYLKGLLANYNIVLPNALNGTFNLKNGTYIDILPVLVMF
                     FVTGIVLMNSKLALRFNSFLVILKFSALALFIFVGIFFIDHNNWSHFAPYGVGQITGG
                     KTGIFAGASVMFFAFLGFESISMAVDEVKEPQKTIPKGIILSLIIVTALYIVVTTILT
                     GIVHYTKLNVPDAVAFALRNIRLYWAADYVSIVAILTLITVCISMTYALARTIYSISR
                     DGLLPKSLYTLTKKNKVPQNATLVTGLLAMICAGIFPLSSLAEFVNICTLAYLIILSG
                     AIIKLRRIEGEPKANEFKTPLVPFLPMLAIIICLSFMSQYKAFTWIAFAIATIIGTLI
                     YLAYGYTHSIENK"
BASE COUNT         7246 a         3250 c         3795 g         6733 t
ORIGIN      
        1 aaaaaattgc caaaatgaca attgcgatag tccgtacggg attcgaaccc gtgttaccgc
       61 cgtgaaaagg cggtgtctta accccttgac caacggacca gaagttttgg aggatatctc
      121 cttaacactc ttactattat agcagattga ttttttttgt ctatactttt tttaaaaaaa
      181 atttgatttt ttttaaaccg caagttgtca agtcaagtgc aatcagttca tcgataacta
      241 gagttccaga ggttaagctg ttcgggatag ctcaaacagg aatgttgagg attgctattg
      301 aagaagtcgt cttgggcgct cattgatggc tgtaagataa ttgtcaagtt cttcagaggt
      361 tagtggatta agtgagattc ctttagggac atattctctg aggaggccat tgaagttctc
      421 gtttgttcct ctctcatgtg aagaataggg atgtgcaaag taaacgtcaa cagcttctaa
      481 ggttgagagt aaactaaact cagaaccatt atccgctgtg atggatgcaa taggatactg
      541 actgatgaga tgcgtgacag cgcggttaat ggtttgggac tgcttgtctt ctagcttaac
      601 tcctagtgca tagcgtgtct ggcgctctac caaagtcaac ataacagctt cacctttggt
      661 tttcttgccg agaatcaaat caatctccca atgcccaaat tcagaatgat cattaatata
      721 ttctggacgt tcttcgatag atttacctaa agtcttctta ttcgtcttca tgactttctt
      781 agaacgtttt ctgatactaa ccatcttagg caaatcgatt ggtttaatag acacgttgcc
      841 cactatcagc gaaataggcg ttgaagaagg tttgttttcc attcttatcc tttacctgat
      901 ctactgaacc acgttttatt tctcggcaga ttgtagaaca gtgacgcccc agaagtcgag
      961 caatctcaac gggtttcttt cccattttaa gataagcagc aatttcaccg cgttctgtgg
     1021 ctgaaagatg agaataggat gattttctgg tagaattaat attagacatg ttcatctgct
     1081 ttccatactg aattggggaa ttctagtata tcagacgaac atgtcttttt tgttgcactt
     1141 cattttacaa cgcgggatat aatgttattt tctagttttt tcaaaataaa tattgacagt
     1201 tttagataat ttttgttaaa atgatgtggt taaggtctca tagctcagct ggatagagca
     1261 ttcgccttct aagcgaacgg tcgcaggttc gaatcctgct gggatcaaag ataaaaaagc
     1321 actgttttag tgcttttttt gtatttacct tagtgtattg aaaagatagg atttagtctg
     1381 tcttttttta atatttgctt ttaattatac cgaactatta tctaataaag tggtaagagt
     1441 tagttattcc agttcacact ctcttactta tgataaggac tgccttttgt aatcataaaa
     1501 gcacgataaa tttgctcagt aagaactaga cgcattaact gatgaggtaa ggttaacaat
     1561 ccaaaactca ttagcatatt agctcttttt ttaataattg aatctaaccc aagacttcca
     1621 ccaataataa acgtgatagt tgcatatccc ttaacagtaa cccctgatat taattcacta
     1681 aatgtctctg aaggaaactg ttttccttca atagctaatg caattacaaa atcacgttct
     1741 ccaatttttt tatggattcg ctgagcttct ttactcataa tcaattgatt atcagcaaaa
     1801 cttgctttat ctggtgttct ttcatcagtt aactcaatca tttcgaattg acaaaaacgg
     1861 gaaagtcttt tttgatattc tgaaatacca tctttgaggt atctttcttt tagttttcca
     1921 acacaaatta gttttacttt catagcttaa ttgtatcaca agaacattac tttttacaca
     1981 atttatccac aagttatttt tttcaactac taataaaaac ctttgtacaa aggtctttat
     2041 tagtaaaaag aaaagtaatc cacagcctgt ggattacttt tctttttttt atttttaagg
     2101 tataattaag caaagttcta taagctatgg acaaataatt cggaggacaa aacatgccaa
     2161 gtatgaaaca tatcttaaaa tccttaagta ttttactaat tggattttta ggaggattaa
     2221 tagcaattat tacattcaat aatctctacc cacattctcc ttcaaaaata aattcaggta
     2281 aggcaacaac tagtaatatg gtttttaaca acacaaccaa tactactaaa gctgtcaaag
     2341 ctgttcaaaa tgcagttgta tcagttatta attatcaaga taacccttct tcatcccttt
     2401 ctaaccctta tacaaaactc tttggagaag ggcgttcaaa agagaataag gatgctgaat
     2461 tatctatttt tagtgaagga tctggggtca tttatcgaaa agatggcaac tccgcttacg
     2521 ttgttactaa taaccatgtt atcgacggag ctaaacggat tgaaattctt atggcagacg
     2581 gatctaaagt tgttggtgaa ttagttggag ctgatactta ttcggattta gctgttgtta
     2641 agatctcttc agataagata aaaacagtag ctgaatttgc agactctaca aaactaaatg
     2701 ttggagaagt tgctattgct atcggcagcc cactaggaac acaatacgct aattctgtta
     2761 ctcaaggaat cgtctctagt ttaagtcgta ctgtaacttt aaaaaacgag aatggtgaga
     2821 ctgtctcaac aaatgctatt cagacagatg ctgctattaa tcctggaaac tctggtggac
     2881 cactaattaa tattgagggg caagtaatcg gaattaattc aagtaaaatt tcttctaccc
     2941 caactggtag caacggtaat agtggtgctg ttgaaggaat tggttttgct atcccatcta
     3001 ctgatgttat taaaattatt aaacagctag aaactaatgg tgaagttatc agacctgctc
     3061 ttggaatatc catggtcaat ttaaatgatt tatccacaaa tgctcttagc caaattaata
     3121 ttccaactag tgtaactggt ggtattgtag tagcagaagt taaggaagga atgccggcat
     3181 ctggcaaact tgctcagtac gatgtgatta cagaaattga tggcaaaaca gttaattcaa
     3241 ttagtgattt acaaagtagt ctatacggac acgatattaa tgatactatt aaagtaactt
     3301 tttatagagg aactacaaag aaaaaagcag atatcaaatt aacaaaaact actcaagatt
     3361 tgactaaaac gcagtaaaca agctacctaa atactattac attttatcac ataaaacagt
     3421 ccaaaggact gttttatgtt tcttattcta tccaggaact cccttatgac aaaagaatta
     3481 ttgatagacc taccaattga agatattgtt acaaatccct atcagccaag gatacaattt
     3541 aatcaaagag aactccaaga cctagcaact tctattaaat caaacggcct cattcaacct
     3601 attattgttc gaaaatctga catttttggc tatgagttag ttgctggaga acgacgactt
     3661 aaagcttcaa aaatggctgg tctaaaaaaa gttccagcta tcatcaagaa gatctctaca
     3721 ctcgagagca tgcaacaagc tatagttgaa aatttacaac gttctaacct taacgctatc
     3781 gaagaagcta aagcctatca gttattggtt gaaaaaaaac acatgactca cgatgagatt
     3841 gctaaatata tgggaaaatc aagaccttat attagcaata ccttacgtct gttacaactc
     3901 ccaacaccta tcattaaagc aattgaagaa ggaaaaatta gtgcgggaca cgcgcgtgct
     3961 cttttaactt tgagtgatga taagcaacaa ctgtacctca ctcataaaat acaaaatgaa
     4021 ggcctaagtg ttaggcaaat tgagcaactg gttacttcta ctccaagttc gaagctatct
     4081 aaaaaaacta aaaatatttt tgccacttct ttagagaaac aattggctaa atcattggga
     4141 ctctctgtca atatgaagct gacagcaaac catagtgggt accttcagat atctttttcc
     4201 aatgatgatg aattaaacag aattatcaac aagctaaagt agcttgttga tattctgttt
     4261 tttctttttt agttttccac atgaaaaata gttgaaaaca atagcggtgt caccttaaaa
     4321 tagcttttcc acaggttgtg gagaactcaa gttaacagtg ttaatttatt ttccacagat
     4381 tgtggaaaaa ctaactatta tccattgttc tgtggaaaac tagaatagtt tatggtagaa
     4441 tagttctaga attatccaca agaaggaacc tagtatgact gaaaatgaac aaattttttg
     4501 gaacagggtc ttggaattag ctcagagtca attaaaacag gcaacttatg aattttttgt
     4561 tcatgatgcc cgtctattaa aggtcgataa gcatattgca actatttact tagatcaaat
     4621 gaaagaactc ttttgggaaa aaaatcttaa agatgttatt cttactgctg gttttgaagt
     4681 ttataacgct caaatttctg ttgactatgt tttcgaagaa gacctaatga ttgagcaaaa
     4741 tcagaccaaa atcaatcaaa aacctaagca gcaagcctta aattctttgc ctactgttac
     4801 ttcagattta aactcgaaat atagttttga aaactttatt caaggagatg aaaatcgttg
     4861 ggctgttgct gcttcaatag cagtagctaa tactcctgga actacctata atcctttgtt
     4921 tatttggggt ggccctgggc ttgggaaaac ccatttatta aatgctattg gtaattctgt
     4981 actattagaa aatccaaatg ctcgaattaa atatatcaca gctgaaaact ttattaatga
     5041 gtttgttatc catattcgcc ttgataccat ggatgaattg aaagaaaaat ttcgtaattt
     5101 agatttactc cttattgatg atatccaatc tttagctaaa aaaacgctct ctggaacaca
     5161 agaagagttc tttaatactt ttaatgcact tcataataat aacaaacaaa ttgtcctaac
     5221 aagcgaccgt acaccagatc atctcaatga tttagaagat cgattagtta ctcgttttaa
     5281 atggggatta acagtcaata tcacacctcc tgattttgaa acacgagtgg ctattttgac
     5341 aaataaaatt caagaatata actttatttt tcctcaagat accattgagt atttggctgg
     5401 tcaatttgat tctaatgtca gagatttaga aggtgcctta aaagatatta gtctggttgc
     5461 taatttcaaa caaattgaca cgattactgt tgacattgct gccgaagcta ttcgcgccag
     5521 aaagcaagat ggacctaaaa tgacagttat tcccatcgaa gaaattcaag cgcaagttgg
     5581 aaaattttac ggtgttaccg tcaaagaaat taaagctact aaacgaacac aaaatattgt
     5641 tttagcaaga caagtagcta tgtttttagc acgtgaaatg acagataaca gtcttcctaa
     5701 aattggaaaa gaatttggtg gcagagacca ttcaacagta ctccatgcct ataataaaat
     5761 caaaaacatg atcagccagg acgaaagcct taggatcgaa attgaaacca taaaaaacaa
     5821 aattaaataa catgtggaaa agaatatctt ttatgaaata gttatccaca agttgtgaac
     5881 aaccatttag tcttggattc tctcgtttat ttagagttat ccactatata cacaagacct
     5941 actactacta cttattatta tacttattaa ataaaggagt tctcatgatt caattttcaa
     6001 ttaatcgcac attatttatt catgctttaa atgcaactaa acgtgctatt agcactaaaa
     6061 atgccattcc tattctttca tcaataaaaa ttgaagtcac ttctacagga gtaactttaa
     6121 cagggtctaa cggtcaaata tcaattgaaa acactattcc tgtaagtaat gaaaatgctg
     6181 gtttgctaat tacctctcca ggagctattt tattagaagc tagttttttt attaatatta
     6241 tttcaagttt gccagatatt agtataaatg ttaaagaaat tgaacaacac caagttgttt
     6301 taaccagtgg taaatcagag attaccttaa aaggaaaaga tgttgaccag tatcctcgtc
     6361 tacaagaagt atcaaccgaa aatcctttga ttttaaaaac aaaattattg aagtctatta
     6421 ttgctgaaac agcttttgca gccagtttac aagaaagtcg tcctatttta acaggagttc
     6481 atattgtatt aagcaatcat aaagatttta aagcagtagc gactgactct catcgtatga
     6541 gccaacgttt aatcactttg gacaatactt cagcagattt tgatgtggtt attccaagta
     6601 aatctttgag agaattttca gcagtattta cagatgatat tgagaccgtt gaggtatttt
     6661 tctcaccaag ccaaatcttg ttcagaagtg aacacatttc tttttataca cgcctcttag
     6721 aaggaaatta tcccgataca gaccgtttat taatgacaga atttgagacg gaggttgttt
     6781 tcaataccca atcccttcgc cacgctatgg aacgtgcctt cttgatttct aatgctactc
     6841 aaaatggtac tgttaagctt gagattactc aaaatcatat ttcagctcat gttaactcac
     6901 ctgaggttgg taaggtaaac gaggatttgg atattgttag tcagtctggt agtgatttaa
     6961 ctatcagctt caatccaact taccttattg agtctttaaa agctattaaa agtgagacag
     7021 taaaaattca tttcttatca ccagttcgac cattcaccct aacaccaggc gatgaggaag
     7081 aaagttttat ccaattaatt acaccagtac gaacaaacta agtaagaaaa agctcccttt
     7141 taggagtttt tttgttatta taaatattaa cgataatata agtggagaaa agggaatgta
     7201 tcaaattgga tcatttgttg aaatgaaaaa acctcatgct tgtgtaatta aagaaactgg
     7261 taaaaaggct aatcaatgga aggtactgag agtaggagct gatattaaaa ttcagtgtac
     7321 taactgtcag catgtgatta tgatgagtcg ttatgatttt gagcgaaaat taaaaaaagt
     7381 actgcaacca tgaaagtcct tttaaataaa taattctagc tatatttgca accaatactt
     7441 tcctaaaaaa ttgctagtat gccgttggaa aattagctat tctaatgtta tcgaaagaag
     7501 aaagatggcc attgacaatg acgaaagttg tagcacagtt acttagtttc tcggcaaact
     7561 atatcaaaat gagaataata caccaaactt tgataattta aatgaaggtg aaagagtggc
     7621 ataatgataa gcaaatctga aattttcttc ttattcatac cgctttttct tctatttttt
     7681 ggtataataa tcttgattga aatttgaatg gagattcgct aaatggcttt aacagcaggt
     7741 attgtaggct taccaaatgt tggtaaatca accttattta acgcaattac aaaagcagga
     7801 gcagaagctg ctaattatcc ttttgcgact attgatccca atgttggtat ggtagaggtt
     7861 ccagatgagc gtctgcaaaa attgacagaa ttgattacac ctaaaaaaac agttccgaca
     7921 acctttgaat ttactgatat tgcaggtatc gttaaaggtg cttctagagg ggaaggtcta
     7981 ggaaataaat ttttagctaa tattcgtgaa gtcgatgcta ttgttcatgt ggtacgtgct
     8041 tttgatgatg aaaatgtcat gcgtgaacaa ggtcgtgagg atgctttcgt tgatcctata
     8101 gcagatattg acactattaa tcttgaatta atcttagctg atttagagtc aatcaataaa
     8161 cgttatgcgc gtgttgaaaa aatggcacga actcaaaaag ataaagaatc agtagcagag
     8221 tttaatgttt tgcaaaagat taaacctgtt ttggaagatg ggaaatcagc taggacaatt
     8281 gagtttacag aagatgaagc aaaagttgtt aaaggtctct ttttattaac aactaaacct
     8341 gttttatatg tagctaatgt cgatgaagat aaagttgcta atccagatgg tattgattat
     8401 gtcaaacaaa ttcgtgactt tgcagctact gaaaatgctg aagtagttgt tatctcagcg
     8461 cgtgcagaag aagaaatttc agagcttgac gatgaggata aagaagaatt tttggaagct
     8521 atcggtctta ctgaatcagg cgttgataaa ttaaccagag cagcttatca tctcttaggc
     8581 cttggaacct attttacagc aggtgaaaaa gaggttcgtg cttggacgtt taagcgtggt
     8641 ataaaagctc cacaagctgc tggtattatc cattcagatt ttgaaagagg ttttattcgt
     8701 gcagtaacca tgtcttatga tgatctaatg acctacggtt cagaaaaagc cgtcaaagaa
     8761 gctggacgct tgcgtgaaga aggaaaagaa tatgttgtcc aagatgggga catcatggaa
     8821 ttcagattta atgtgtaatt atattaaaac aatatcagaa ggttggaaga acattccagc
     8881 ccttttggca ttttagaaag agaaaatatg gtaaaaatga ttgttggtct gggaaatcca
     8941 ggctctaaat atgaaaaaac aaagcacaat attggtttta tggctattga caatattatc
     9001 aagaaccttg acgttacctt tacagatgat aaaaatttta aagcacagat aggaagtact
     9061 tttattaatc atgaaaaagt ttactttgtg aaacctacta cttttatgaa taatagcggc
     9121 atagcagtaa aagcattact aacctactat aatattgaca taacagattt aattgttatc
     9181 tatgatgatt tagacatgga agtcagtaaa ttacgtttac gtagtaaggg ttcagcagga
     9241 ggacataatg gcattaagtc aatcattgcc cacattggaa ctcaggaatt taaccgaatc
     9301 aaagttggta ttggacgacc tttaaaaggt atgactgtta ttaaccatgt gatgggtcaa
     9361 ttcaataccg aagataatat tgctatttcg ttaactcttg acagagttgt caatgctgtc
     9421 aagttttatt tacaagaaaa tgattttgaa aaaacaatgc agaaatttaa tggataatca
     9481 tgaatatttt agaattattt agtcagaata agaaagtcca atcctggcac tctggattaa
     9541 ccaccttagg aagacaactg gtaatggggt tatcgggttc aagtaaagca ttggctatag
     9601 cttccgctta tttagatgat caaaaaaaaa tagttgtggt tacatcaact caaaatgagg
     9661 ttgaaaaatt agccagcgat ttatctagtt tacttgatga agaacttgtt ttccaatttt
     9721 ttgcagacga tgtggctgca gcggaattta tctttgcgtc aatggataaa gctctatcaa
     9781 gaatagaaac cctgcaattt ttaaggaatc ctaaatctca gggcgtttta attgttagtt
     9841 tatcaggctt aagaacttta ttgccaaacc cagatgtttt tacaaagagt cagattcaac
     9901 taacagttgg agaagattat gatagtgata ctcttactaa acaactgatg acaattggat
     9961 atcagaaggt ctcacaggtt attagtccgg gagaatttag ccgtcgaggg gatattttag
    10021 atatctatga gattacacaa gaattgcctt atcgattgga attttttggt gatgatattg
    10081 atagtattag gcaatttcat ccagaaactc aaaaatcttt tgaacaacta gaaggtattt
    10141 ctattaatcc agcaagtgat cttatttttg aggctagtga ttttcaacgt ggcattgagc
    10201 aattagaaaa ggctctacaa acagcacaag atgataaaaa atcttattta gaagatgtat
    10261 tagctgtttc aaaaaacggt tttaaacata aggatatccg taaatttcaa tcattatttt
    10321 atgaaaaaga gtggtcatta ttagattata ttcctaaggg aacgccaatc ttttttgatg
    10381 attttcaaaa actagttgat aaaaacgcaa gatttgattt agagattgct aatctcttga
    10441 cagaagattt acagcaagga aaggctcttt ccaatcttaa ctactttgca gataattatc
    10501 gagagcttag gcactataag ccagcgacct tcttttcaaa ttttcataag ggacttggaa
    10561 atatcaaatt tgatcagatg catcagctaa ctcagtatgc catgcaggaa ttttttaatc
    10621 aatttccttt gttgattgat gagattaaac ggtatcaaaa aaatcaaaca acggttattg
    10681 tacaggtaga gtctcagtat gcttacgaac gacttgaaaa atcttttcaa gattaccaat
    10741 ttcgccttcc tttagtgagt gctaatcaaa ttgtttcacg tgaatcacaa attgtaattg
    10801 gagctatctc cagtggtttt tattttgctg atgaaaagtt agcgttaatc acagagcatg
    10861 aaatttatca taaaaagatc aaacgacgcg ctagacgatc taatattagc aatgctgagc
    10921 gtttgaaaga ttacaatgag ttagcagtag gtgattacgt ggttcataat gtccatggta
    10981 tcggtcgctt tcttggaatt gaaacgattc agattcaggg aatccatcga gattatgtta
    11041 ctattcaata tcaaaattca gaccgtattt ctcttccaat tgaccaaatt agtagcttat
    11101 caaagtacgt ttctgctgat ggaaaagaac ctaaaattaa taaactcaat gatggtcgtt
    11161 ttcaaaagac aaagcaaaag gtcgctagac aagtagagga tattgctgat gaccttctaa
    11221 aattatatgc tgaaagaagt cagcaaaaag gattttcatt ttcaccagat gatgacttgc
    11281 agcgcgcttt tgatgatgat tttgcttttg tagaaacaga agatcaactt aggtctataa
    11341 aggaaattaa agctgatatg gagagcatgc agcctatgga tcgtctttta gtaggcgatg
    11401 taggatttgg taagacagaa gtagctatga gggcagcctt taaagcggtg aatgatcaca
    11461 aacaagtagc tgtcttagtt ccaaccacag tcttggccca gcagcattat gaaaacttca
    11521 aagcacgctt tgaaaattac cctgttgagg ttgacgtctt aagtcgtttc cgtagtaaaa
    11581 aagagcaagc tgaaacacta gaacgtatac gaaaaggtca aattgatatt attatcggaa
    11641 cccatcgact cctatcaaaa gatgtggtct tttctgattt aggattgatt gtgattgatg
    11701 aggaacaacg gtttggtgtt aagcataaag aaactttaaa ggaattaaaa actaaggttg
    11761 acgtcttaac cttaacagct actccgattc ctagaacctt acacatgtct atgttaggta
    11821 tccgagattt atcggttatt gagaccccac caaccaatcg ttatcctgtt caaacctatg
    11881 ttttggaaaa taatccaggt ctcgttagag aagctatcat tcgtgaaatg gatcgtggag
    11941 gacaaatttt ttacgtttac aataaagttg acactattga aaagaaagtt gcagagctac
    12001 aagaattagt cccagaagct tctatcggtt ttgttcatgg gcaaatgagt gaaattcaac
    12061 ttgaaaatac cttgattgac tttataaatg gtgattatga tgtccttgtg gctacaacaa
    12121 tcatcgaaac aggagttgac atttctaatg taaacacttt gtttattgag aatgctgatc
    12181 atatgggatt gtcaacttta tatcaactac gagggcgcgt cggaagaagt aatcgtattg
    12241 cttatgctta cctgatgtat cgtcctgata aggtcctaac agaagtctct gaaaagcgtt
    12301 tagaggctat taaaggcttt actgaattag gttcaggctt caagattgct atgcgagatt
    12361 tgtctatacg aggagcaggt aatattttag gagcttctca aagtggcttt attgattcgg
    12421 tcggttttga aatgtattct cagttattgg aacaggctat tgctagcaag caaggaaaaa
    12481 cgactgttcg ccaaaaaggt aatactgaaa tcaatcttca gattgatgcc tatttaccag
    12541 atgattatat tgcagatgag cgccaaaaaa ttgacattta caagcgtatt cgagaaattc
    12601 aatcaagaga agattatctc aatttgcaag atgagcttat ggatcgtttt ggagagtatc
    12661 ctgatcaagt tgcctatttg ttagagatag ctctgctaaa acattatatg gacaatgcct
    12721 ttgcggaatt agttgaacgc aaaaataatc aggtcattgt tcgatttgaa gtaacttctt
    12781 taacttattt cttgactcag gattatttcg aagccttatc gaaaacccat cttaaagcta
    12841 aaattagtga acatcagggg aaaatcgata tcgtctttga cgttcgccat caaaaagatt
    12901 atagaatttt agaagaattg atgctatttg gagaaaggct tagtgagata aaaatcagaa
    12961 aaaacaattc agtttttaaa taataatttg aaacaacttt tagactgaat agtattaatg
    13021 acaatggaac gaactagctc tttatacttt tgtcaaaaat ctaagatctt tgctgcgaaa
    13081 ttaggatctt ttctaccatt taaaaaataa aaatgataaa atgaagagga ttgtaggaga
    13141 aattatgaga ctagataaat atctaaaggt atcgcgcctt attaaacgtc gttcagtagc
    13201 aaaagaagtt gcggataagg gacgaattaa agttaatggg atacttgcta aaagttcaac
    13261 gaatataaaa ctaaatgatc acattgaaat tagttttgga aataaattac tgacagtaag
    13321 agtcattgaa ataaaagata gtacaaaaaa agaagatgct cttaagatgt atgagataat
    13381 cagtgaaaca aggataacat taaatgaaga agcctagtat tgttcaatta aataatcatt
    13441 atattaagaa agagaatctc aaaaaaaaat ttgaagaaga agaatctcaa aaaagaaatc
    13501 gttttatggg atggatcctt gtaagtatga tgtttttatt tattttgcca acttataatc
    13561 ttgtcaaaag ttatgttgat tttgaaaagc aaaatcaaca ggtggttaaa ttaaaaaaag
    13621 agtataatga attgtcaaag agtacaaaaa aagaaaaaca attagcagaa cgactaaaag
    13681 atgataattt tgtcaaaaaa tatgctaggg caaaatacta tttatcgcgt gaaggagaaa
    13741 tgatttatcc tattccagga ctattaccaa aatgatgatg gacaatattg taaaaaaaat
    13801 agaagcattt cttgcttttt ctgataaaaa attagcagag ctgcaacagg aaaatcaaaa
    13861 agttaaagaa gaaagtcagt atattcaaaa aaactagaaa ggagtcaata tgagaaaatt
    13921 attagcggct atgttaatga ctttttttct gactccttta ccagtgatta gtacagaaaa
    13981 aaaacttata ttttcaaaaa atgctgttta tcaattgaaa caagatgtcg ttcaatcaac
    14041 acaattctat aatcaaatac cctctaatcc aaatctttat caagaaacgt gtgcctataa
    14101 agacagtgat ttaactctac cagcaggaag attaggtgta aatcaaccat tacttattaa
    14161 atcgcttgtg cttaacaaag aatctttacc ggtttttgag ttagctgatg gtacctatgt
    14221 tgaggctaat cgacaattga tttatgacga tattgtactt aatcaagtag atatagatag
    14281 ctatttttgg acacaaaaga aacttaggct ttattcagcc ccttatgttt taggtacgca
    14341 aacaattcct tcttcttttt catttgctca aaaagttcat gccactcaaa tggcacaaac
    14401 aaaccatgga acttattatc ttattgatga taagggctgg gcatcacaag aagatctagt
    14461 tcaatttgat aaccgcatgt taaaagtcca ggaaatgctc ttacaaaaat ataataaccc
    14521 aaattattca atttttgtaa agcaactcaa cacacaaaca agtgctggta ttaatgctga
    14581 taaaaaaatg tatgctgcaa gtatctcgaa gttagcacca ctttatattg ttcaaaaaca
    14641 attacaaaaa aagaaattag cagagaataa aactttgact tatactaaag atgttaatca
    14701 tttttatgga gactatgatc cattgggaag tggtaaaatt agtaaaatag ctgataataa
    14761 agattatcgt gttgaagacc tactgaaagc tgtagcacaa caatcggata atgtagcaac
    14821 taatatttta ggttattatc tatgtcatca gtatgataaa gctttccgct cagagataaa
    14881 agctttatca ggtatcgatt gggatatgga gcagcgctta ttaacttctc gttcagctgc
    14941 aaatatgatg gaagctattt atcatcaaaa aggccaaatt atttcttacc tttcaaatac
    15001 cgaatttgat caacaacgta tcacaaaaaa tattactgtt ccagttgcac ataaaattgg
    15061 tgatgcttat gattataaac atgacgttgc tattgtttac ggtaatactc catttatttt
    15121 gtctattttt acaaataaat caacctatga agatattacg gctattgcag atgacgttta
    15181 tggtatttta aaatgatgac ctatcaagaa atttttaatg aaataaaaaa taaagcctac
    15241 tttaaaaatc atagacatgt gttaatagcc gtatctggtg gagtagattc aatgaattta
    15301 ttgcactttt tatacctgtt tcaagacaaa ttgaaaattc gtattggtat tgctcatgtt
    15361 aatcacaaac aaagatcaga atcagattca gaagaagctt atttaaagtg ttgggctaaa
    15421 aaacatgaca tacctattta tgtttctaat tttgaaggaa tattttcaga aaaagcagca
    15481 cgtgattggc gctatgcttt ttttaagagt attatgttaa aaaataactt ttcagcttta
    15541 gtaacagctc accattcaga tgatcaagca gaaactattt tgatgaggct aattagagga
    15601 agccgattga ggcacttgtc gggtataaaa agcgtgcaac catttgccaa tggtcaactt
    15661 ataagacctt ttttaacttt ctcaaaaaag gactttccag aaatttttca ttttgaagat
    15721 tcttcaaata gggaattatc atttttaaga aatagagtta gaaataatta tttaccattg
    15781 ttaaagcagg aaaatcctag gttcattcag ggattaaatc aattagcact tgaaaatagc
    15841 ttactttttc aagcttttaa ggagctaaca aatcatatta ctaccactga tttaacagaa
    15901 tttaatgagc aatctaagtc tattcaatac tttttgttac aagattattt agaaggtttt
    15961 ccagatttag atttaaaaaa atctcaattt actcaattat tgcaaattat ccaaactgct
    16021 aaacaaggct attattatct caaaaaagac tattatatat tcattgataa attctctttt
    16081 aaaattacaa aaatcgttcc taagactgag ttagttaaag atgaaaaaat gttagaatac
    16141 gatagtaact tatgctacag agattattgt ttttcattta tgccaaaaag taacgaagat
    16201 caaggacagg taagtatacc tttatttagt ttatcgtcta ttaaattaag aagtcgccaa
    16261 tctggagatt atatttcttt tggtcacttt tcaaaaaaaa taagacgttt atttatagat
    16321 gaaaaattca caatagctga acgccaaaat gctattattg gagagcaaga tgagcagatt
    16381 atatttgtat tgataggtaa taaaacttat ttgagaaaag cttgtaaaca tgatataatg
    16441 ttggctaaac tgtatattga taaattagaa aaagggtgac agcatgctcg agcaagatat
    16501 tcaaaaaatt ctttactctg aaaatgatat tattcggaaa actaaaaaat taggagaaca
    16561 attaacaaaa gattatcaag aaaaaaatcc gcttatgatt ggtgtattaa aaggatcagt
    16621 tccttttatg gcagaactaa tgaaacacat cgatactcat gttgaaattg attttatggt
    16681 agtatcaagt tatcatggcg gtacatctag cagtggtgaa gttaaaattt taaaagatgt
    16741 agataccaat attgaaggaa gagatatcat aattgttgaa gatattattg acaccggtcg
    16801 caccttaaaa tatttacgag atatgtttaa gtaccgtaaa gctaatacta tcaaaattgc
    16861 aacactgttt gataaacctg aaggtcgtgt tgttaaaatt gaagcagatt atgtttgtta
    16921 caatattcca aatgaattta tcgtaggctt tggtttagat tacgcagaaa attatcgcaa
    16981 tcttccttac gtaggtgtat taaaagaaga agtctattca aaatagaaaa aggtcaatgt
    17041 ttactgtatg aaaaataata aaaataatgg ttttgttaaa aattctttta tatatatatt
    17101 gatgattata gttgtcatca caggatttca attttatctt aagggaacca gcacacaaag
    17161 ccaacagatt agttattcca aattaattaa acatcttaag gctggagata taaaatcttt
    17221 aagttatcag cctagcggta gtattattga agttaaaggg aaatacgaga aacctcaaaa
    17281 agtgacagtt aattcaggac tatcattttt aggtggaaga gcttcaacac aggtaacaga
    17341 gttctcatct ttagtattac ctagtgatac catcttgaaa gaaatgacag cagcagctga
    17401 taaaaatgga acagagctta cagttaagca ggaaagttca agtggtactt ggattacctt
    17461 cttaatgagc tttttaccta ttgttatttt tgctgctttc atgatgatga tgatgaatca
    17521 aggtggtgga ggagctcgtg gtgctatgag tttcggcaaa aataaggcaa aatctcaatc
    17581 aaaaggtgat gttaaagtga gatttacaga cgttgctggt gccgaagaag aaaaacaaga
    17641 attagtagaa gttgttgatt ttttgaaaaa tcctaaaaaa tataaatcac taggagcacg
    17701 gattccagcg ggagttcttc tagaggggcc tccaggtact ggtaaaacat tactagctaa
    17761 agctgtagca ggtgaagctg gagtgccatt tttcagtatt tcaggttcag attttgtcga
    17821 aatgtttgtc ggtgtaggtg ctagtcgtgt tcgttcttta tttgaggatg ctaaaaaagc
    17881 tgagcgtgcg atcatcttta tcgatgaaat tgacgctgta ggtcgtcgtc gtggtgctgg
    17941 catgggaggc ggtaacgatg aacgagaaca gacccttaac caattactca ttgaaatgga
    18001 tggttttgag ggtaatgaga acattatcgt tattgctgca actaaccgta gtgatgtttt
    18061 agatccagct ttactaagac caggtcgttt tgatcgtaag gttttagttg gtcgccctga
    18121 tgttaaagga cgtgaagcca ttttacgtgt tcatgctaaa aataaaccac ttgcaaatga
    18181 cgttaatttg aaagtagtag cccaacagac tccaggtttt gtaggtgctg atcttgaaaa
    18241 tgttttaaat gaagctgcgt tggttgctgc tcgcagaaat aaaattaaaa ttgatgctag
    18301 tgatattgat gaagctgaag atcgtgttat tgctggacca tcaaagaaag atcgcactat
    18361 ttcgcaaaaa gagcgagaaa tggttgctta tcacgaagct ggtcatacta ttgttggttt
    18421 agttttatct aatgcgcgtg tagttcacaa ggtaactatt gtacctcgtg gacgagcagg
    18481 tggttatatg atcgctcttc caaaagaaga tcaaatgctt ctttctaaag aagatctgaa
    18541 agagcaatta gcaggattga tgggtggtcg tgttgctgaa gaaattgttt ttaatgctca
    18601 aacatcaggt gcgtcaaatg actttgagca agctactcag atagcaaggg ccatggttac
    18661 ggaatatggt atgagtgaaa agcttggacc agttcaatat gaaggtaacc atgcgatgat
    18721 gccaggacag atctctcctg aaaaagctta ctctgcccaa acagctcaaa tgattgatga
    18781 tgaggttcgt gaactcttaa atcaagctcg taatcaagca gctgatatca tcaatgagaa
    18841 tcgagatact cataaattga ttgctgaagc tcttctcaaa tatgaaactc tagacgctgc
    18901 acaaattaaa tcaatttatg aaactggtaa aatgccagtt gatttagaaa ctgatgataa
    18961 tgaagctcat gcgttatctt atgacgaaat taaaaataaa atgacagaat ctgaatctgc
    19021 agaatgatat aaaaaagctg aacttaatct ataagttcag cttttttatc aacacaatat
    19081 ccttgtaaac gttatgaatt gtaataggtg cctaattgct agaaatgaga agatgacata
    19141 ctttttttct ttattactta aagtgagaaa gactttggta tttaaaacta gaaaattgtt
    19201 aaagccattt gaaaaaatct attagtgttt tcttagaata atagaagaac agaagatagc
    19261 aaaagtttca gtcaaccaat aagatgaaat ttacaatcat tactaactat gatacactta
    19321 gtagaaaatc atttactata gaaggtgata acatgactat ttttcgtaaa aaaaagaaat
    19381 attccaataa aacagaaatg caaaggcact tcaaagttat tgatttagtt tttttaggcc
    19441 taggttcaat ggttggaaca ggtatcttta cagttactgg cataggcgct gctaagtatg
    19501 caggtcctgc tttaacaata tcgattatca tttccgcgat tgctattgga attttagcct
    19561 tattttatgc agaatttgcg tctcgtatgc cttctaacgg tggtgcttat agttatgttt
    19621 atgcaacctt gggagagttt ccagcatggc ttgttggctg gtatattatt atggaatttt
    19681 taacagctat atctagtgtt gctgttggct ggggaagtta tttaaaagga ttacttgcca
    19741 attataatat agtattacca aacgctttaa atggcacgtt caatcttaag aatggaactt
    19801 acatagatat tcttcctgtt ttagtgatgt ttttcgtgac agggattgtc ctaatgaatt
    19861 cgaaattagc cctgagattc aatagttttt tagttatttt aaaattttca gcactggctt
    19921 tatttatctt tgtaggcatt ttttttattg atcacaataa ttggtctcat tttgctccat
    19981 atggtgtagg acaaattact ggaggtaaaa caggtatctt tgctggtgct tctgttatgt
    20041 tctttgcatt tttaggattt gaatctattt caatggcagt tgatgaagtg aaagaaccac
    20101 aaaaaacaat tcctaaaggt atcattttat ctttgattat tgtaacagca ctctatatag
    20161 ttgtcaccac tattttaacg ggaattgtac actacactaa attaaatgtt ccagacgcgg
    20221 tggcttttgc tttaagaaat attagacttt attgggcagc tgactatgtg tcgatagttg
    20281 ctattttgac tcttattacg gtatgtattt ctatgaccta tgcattagct agaacaattt
    20341 acagtattag tagagatggt ttattaccta aatcacttta tactctcact aaaaaaaata
    20401 aagtgcctca aaatgctact cttgtcactg gactacttgc tatgatttgt gcgggaatat
    20461 ttcctttatc gagtctagca gagtttgtta atatttgtac tttagcatat ttaattattc
    20521 tgtcgggtgc aattattaaa ctcagaagaa tagaaggaga accaaaagca aatgaattta
    20581 aaactcctct agtaccattc ctaccaatgt tggcaattat catttgtcta tcatttatga
    20641 gccaatataa agcttttact tggattgctt ttgctattgc cacaattatt ggaacattaa
    20701 tctacttagc ttatggttat actcattcaa tagaaaataa ataatgtttt gataataaga
    20761 tttgacatta cattatagac tataatgttt agaagtaaat gagtagtaaa atcaatacct
    20821 acttacttat caaagttgta atatttaaaa ttacccaacc cctagagaat tgattagtct
    20881 ctaggggttg attggcacaa tgacatagac tctaaaacga ttttaatact aaaatatata
    20941 gatataaatt tcaaaaaaga aaattagttc atttttgtta cacaataaaa tttgttattt
    21001 agcagtaata taattgaaaa acag
//
LOCUS       DATTYN010000036        20894 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.36, whole genome shotgun sequence.
ACCESSION   DATTYN010000036 DATTYN010000000
VERSION     DATTYN010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20894
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.36"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..327
                     /locus_tag="VB649_001584"
     CDS             <1..327
                     /locus_tag="VB649_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP1670523.1"
                     /translation="KDGQPGKPAPQTPEVPQKPDTAPHTPKTPQIPGQSKDVTPAPQA
                     PSNRGLNKPQTQGGNQLAKTPVAHDTHRQLPATGETTNPFFTAAAVAIMTTAGVVAVA
                     KRQENN"
     gene            513..950
                     /gene="msrB"
                     /locus_tag="VB649_001585"
     CDS             513..950
                     /gene="msrB"
                     /locus_tag="VB649_001585"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEP1670524.1"
                     /translation="METSDELKQRIGDLSYEVTQHAATESPFTGEYDDFFEKGIYVDI
                     VSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHV
                     FSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET"
     gene            1080..2099
                     /locus_tag="VB649_001586"
     CDS             1080..2099
                     /locus_tag="VB649_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEP1670525.1"
                     /translation="MSTHLRKLPGLLLCLLLALPAWCLGHLFPIIGAPVFAILLGMLL
                     ALFYEHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIISTIATALL
                     VAYGSHKWLRIDVNTATLVGVGSSICGGAAIAATAPVIKAKDDEVAKAISVIFLFNML
                     AALLFPSLGQLLGLSNEGFSIFAGTAVNDTSSVTATATAWDALHHSNTLDGATIVKLT
                     RTLAILPITLGLSLYRAKKEHDIVTEENFSLRKSFPRFILFFLLASLITTLMTSLGVS
                     ADVFYSLKTLSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLAMQL
                     SLGIW"
     gene            2306..2731
                     /locus_tag="VB649_001587"
     CDS             2306..2731
                     /locus_tag="VB649_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEP1670526.1"
                     /translation="MKRKFLIGSHGRLASGLQSSIDILAGMGQALETIDAYVDDSDYT
                     SQIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLV
                     FLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD"
     gene            2758..3249
                     /locus_tag="VB649_001588"
     CDS             2758..3249
                     /locus_tag="VB649_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEP1670527.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVN
                     VANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQ
                     LVN"
     gene            3266..4075
                     /locus_tag="VB649_001589"
     CDS             3266..4075
                     /locus_tag="VB649_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEP1670528.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIIYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFYLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITRGAISKQTTFDSKESEEEDFFA"
     gene            4072..4899
                     /locus_tag="VB649_001590"
     CDS             4072..4899
                     /locus_tag="VB649_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEP1670529.1"
                     /translation="MTSQDNLTKEDRKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINRFYKTDKDKAEALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPDFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASAGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGLMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQDYLDQLFIGIVPLMVTLAAFWLLRKKVNINWIMFGIMFLGIILGLLGIC"
     gene            5035..6684
                     /locus_tag="VB649_001591"
     CDS             5035..6684
                     /locus_tag="VB649_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEP1670530.1"
                     /translation="MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAP
                     QQLGLYRDINATATRYHRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHS
                     SQTSPELLLFSPNQGLLFASNPHLGNAFSKSVYIQEVLRAAHPPKTLFKVAMDSEDGH
                     YLMIIKPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIAS
                     SLDKINSQYLHHYFVFQDNRAFITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVI
                     FVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQ
                     MVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIV
                     IQLTKLLRYSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLAVPK
                     LFLLPLIENAIKYGLKERHDVKINIACYYQDDHIIFSVRDNGSGIDAHHQKVIREQLE
                     AGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE"
     gene            6688..7476
                     /locus_tag="VB649_001592"
     CDS             6688..7476
                     /locus_tag="VB649_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1670531.1"
                     /translation="MYKLVIIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLI
                     KESQPDIVLTDINMPIMTAFDMFESTKDQTYAKIILSGYADFPNARSAIHYGVLEFLT
                     KPIEKAALWECLQTIIAKIEKQKGSNQKTDACVYIPLPQMTDQIPEVVKDILEWVHVH
                     FQDKISTSRLAHDLGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVY
                     EIAQAVGIYDYRYFDRVFKKYLGQTVKAFKEEHFMKDTDRSKPC"
     gene            7470..8516
                     /locus_tag="VB649_001593"
     CDS             7470..8516
                     /locus_tag="VB649_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEP1670532.1"
                     /translation="MLKLKRKWLLSFLLVIIILAIVNVAMCILSSSKKDSAKELVILT
                     PNSQTILTGTIPAFEEKYGVKVRLIQGGTGQLIDQLGRKDKPLNADIFFGGNYTQFES
                     HKDLFESYVSPQVSTVISDYQLPSHRATPYTINGSVLIVNNELARGLHITSYEDLLQP
                     ALKGKIAFADPNSSSSAFSQLTNILLAKGGYTSSEAWEYVKRLLLSMNSIRATSSSDV
                     YESVAEGKMIVGLTYEDPCINLQKSGANVSIVYPDEGTVFVPSSVAIIKKAKAMKEAK
                     QFINFILSSDVQNAFGQSTSNRPIRRDAQTSHEMKPLDEIITLKEDYGYVTRHKKKIL
                     NTYNRLHEALERGK"
     gene            8631..10028
                     /locus_tag="VB649_001594"
     CDS             8631..10028
                     /locus_tag="VB649_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HEP1670533.1"
                     /translation="MTYQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKKWRKEDH
                     LEERKAQLHQVANILRRDRDKYAEIMTKDMGKLFTEAQGEVDLCADIADYYADKADEF
                     LMSMPLETDSGQAYYLKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASIC
                     PRSAQSFEELVLEAGAEAGSITNLFISYAQVSQVIADKRVVGVCLTGSERGGASIAEE
                     AGKNLKKTTLELGGDDAFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDY
                     DRFKELLTKVFKTAKWGDPMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEA
                     IDHPGHFVMPTIIAGLTKDNPIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTI
                     FSSNQEHAKAVAAKIETGMSFINSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEH
                     LIYIPNKTNNSNTKV"
     gene            10130..11926
                     /gene="uvrC"
                     /locus_tag="VB649_001595"
     CDS             10130..11926
                     /gene="uvrC"
                     /locus_tag="VB649_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEP1670534.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSY
                     FRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFL
                     KITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCF
                     YYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNL
                     FPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKK
                     QLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLI
                     IVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEF
                     FLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASA
                     TSEEIQALGIPKTVVEAIQQQITDNKNDRSSP"
     gene            12109..12711
                     /locus_tag="VB649_001596"
     CDS             12109..12711
                     /locus_tag="VB649_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEP1670535.1"
                     /translation="MKFLELNKKRHAIKTFNDQPVDYEDLRTAIEIATLAPSANNIQP
                     WKFVVVQEKKAELAKGLPLANKVQVEQAQYVVALFSDTDLALRSRKIARIGVKSLPDD
                     LIGYYMETLPPRFAAFNEVQTGEYLAINAGIVAMNLVLSLTDQKIASNIILGFDKSMT
                     NEILDIDPRFRPELLITVGYSDEKPEPSYRLPVDEVIERR"
     gene            12836..14245
                     /gene="pepV"
                     /locus_tag="VB649_001597"
     CDS             12836..14245
                     /gene="pepV"
                     /locus_tag="VB649_001597"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEP1670536.1"
                     /translation="MTTIDFKAEVDKRKEAMLADLVDLLRINSERDDRLADDQHPFGP
                     GPVKALEHFLAMAERDGYKTRNIDNYAGDFEFGQGDEVLGIFGHLDVVPAGSGWDTDP
                     YEPVIKDDRIYARGSSDDKGPTMACYYALKIIKELGLPVSKKVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFAGDNKGAFVLHRFQGGLREN
                     MVPESATAVITAPHDLDVLEAALEQFLSEHGVKGSMKATDGKIEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFTFEGAAKDYLHVAGEVLHEDFAAEKLGLAYTDDRMGALSMNA
                     GVFTFDSQSADNTIALNFRYPKGTDAATLKAGLEKLPGVIKVSLSEHEHTPHYVPMDD
                     ELVATLLAVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     ENIYRSAAIYAEAIYELIK"
     gene            complement(14313..15689)
                     /gene="mnmE"
                     /locus_tag="VB649_001598"
     CDS             complement(14313..15689)
                     /gene="mnmE"
                     /locus_tag="VB649_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEP1670537.1"
                     /translation="MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKN
                     LEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEIF
                     QLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLS
                     QLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQGSNRI
                     ILLNKTDLEQKIELEQLPDDYIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLS
                     NARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     misc_feature    15861..15996
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            16025..16525
                     /locus_tag="VB649_001599"
     CDS             16025..16525
                     /locus_tag="VB649_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEP1670538.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDVFVGPSAVAFSNEDVIAPAKVINDFTK
                     TADALEIKGGAIEGAVSSKEEIQALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     NKEGAA"
     gene            16590..16955
                     /gene="rplL"
                     /locus_tag="VB649_001600"
     CDS             16590..16955
                     /gene="rplL"
                     /locus_tag="VB649_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEP1670539.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAAAAA
                     GGAEEAAKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANVKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            17254..17838
                     /locus_tag="VB649_001601"
                     /pseudo
     CDS             17254..17838
                     /locus_tag="VB649_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein"
     gene            18018..18343
                     /locus_tag="VB649_001602"
                     /pseudo
     CDS             18018..18343
                     /locus_tag="VB649_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            18334..18608
                     /locus_tag="VB649_001603"
                     /pseudo
     CDS             18334..18608
                     /locus_tag="VB649_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001883480.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            18657..18866
                     /locus_tag="VB649_001604"
     CDS             18657..18866
                     /locus_tag="VB649_001604"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670540.1"
                     /translation="MTDRVMKKPIRGRQLSKRDLYDEEFFRTHFAKIEIESRLEFLLN
                     RANSLEELLLKAKEVNLTIDLKQKM"
     gene            19132..19827
                     /locus_tag="VB649_001605"
     CDS             19132..19827
                     /locus_tag="VB649_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic (srt) production protein"
                     /protein_id="HEP1670541.1"
                     /translation="MEHQIERLIAEDIYIKVSFGVKQSGLIFIPNYQLDIKEEENHKK
                     YKVYIRETAQFFIYNKEAYKLNRYMRGRELICQLTNDSKSIPKRRRQTIDTLKKKIEE
                     ISLLIELDTENKPYQDIKDDIVKDMAQLDLTITKLQDHIAHLNKVAEVLLNLNNNDIE
                     NRRLARYDYAKMNLTAAIKIEEVEKEIETSQNELNISIDEYEYLVRRLEKFGEILSDS
                     KIIDTSRNEIQWE"
     gene            19978..20664
                     /locus_tag="VB649_001606"
     CDS             19978..20664
                     /locus_tag="VB649_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1670542.1"
                     /translation="MYKILAIDDDKEILKLMKTALEIENYHVITCQEIELPIVFDDFK
                     GYDLILLDIMMPNISGTEFCYKIREEVHSPIIFVSALDGDNEIVQALNIGGDDFIVKP
                     FSLKQFVAKVNSHLKREERAKIKNEAEERVKRSFPPIEIYLEERMLYIDKQPLFLTYR
                     EYEILELLSRHPYKVFTKEEIYEQVYSDEASALFHSISEYIYQIRMKFSSFGINPIKT
                     IRGIGYKWDV"
BASE COUNT         6602 a         3650 c         4330 g         6312 t
ORIGIN      
        1 aaggacggtc aaccaggtaa accggctcct caaacaccag aggtccctca aaaaccagat
       61 accgcaccac atacaccaaa aacccctcag atccctggcc aatcaaaaga cgtgacacct
      121 gcccctcaag ccccttctaa tagaggtcta aacaaaccac aaacacaagg tggtaatcag
      181 ctcgcaaaaa caccagtagc tcacgacaca cacagacaat tgccagcaac aggcgaaaca
      241 accaatccat tctttacagc agctgctgta gctatcatga cgacagctgg agttgtagct
      301 gttgcaaaac gtcaagaaaa caactaatcc tctttttgct acctaactga tggaaagtaa
      361 aactcagaga gaacctcaag gttctctctt ttttgaatca agatagtagc tctaggtata
      421 acgtcttgtc tgaggtgctg tgaacaaatc agttaccgct cacctctttt tttggtaaaa
      481 tgtaagcact aagacatcaa aaggagtttt ccatggaaac atcagatgag ttaaaacaac
      541 gcattggtga tctttcttac gaggtcaccc agcatgcagc aacagaatct ccctttacag
      601 gggaatatga tgattttttt gagaagggta tctatgtcga tattgttagt ggtgaggtct
      661 tgttttcatc actggataaa tttaattctg gctgtggttg gcctgccttt tcaaaaccca
      721 ttgaaaatcg tatggtcaca aaccacgatg actcttcata tgggatgaga cgagtcgagg
      781 ttaaaagccg tgaagcagga tcgcatttgg ggcatgtctt tagtgacggt cccaaagaag
      841 ctggaggctt acgttactgt atcaattcag cagctcttaa atttattcct tatgaccaga
      901 tggaaaaaga aggctatgcc cagtggctca cattgtttga tgagacataa cagggtttca
      961 aaatgactaa aaaagaagcg tcagtgattc ccacaagcac tggattggtg aggcgtacgg
     1021 gtcaatttta caagcctttg taaaaggtct ataataagga atgaaaaaag gaggttagta
     1081 tgtcaactca cttaagaaaa cttccaggcc tgttactttg cttattgtta gctcttccag
     1141 cctggtgttt agggcacttg tttcctatta ttggagcacc tgtttttgct attcttttag
     1201 gaatgttgtt agccttgttt tatgaacatc gtgacaagac taaagaggga attagtttta
     1261 catccaagta tattttacaa acagcagtgg ttttgcttgg ttttggatta aacctaaccc
     1321 aagttatggc agtaggcatg cagtctttac cgattatcat ttcaactatt gcgacagctc
     1381 ttttggtagc ttatggctca cataaatggc tgcgcataga tgtcaataca gccaccttgg
     1441 tgggtgtagg gtcttccatt tgtggggggg ctgctattgc agcgacggct cctgtcatta
     1501 aggcaaagga tgatgaggtt gctaaggcaa tttcagtcat ttttctcttt aatatgttag
     1561 cagctttgct atttccaagt ttaggacaat tactaggctt atctaatgaa ggtttttcta
     1621 tttttgctgg gacagctgtt aacgacacct cttccgtgac tgcaacggcg acggcctggg
     1681 atgcccttca ccattccaat acactagatg gcgcaaccat tgttaaattg actcgcacct
     1741 tggctattct tccaattact ttaggcttat ctctttaccg agcgaaaaaa gagcacgaca
     1801 tcgttacaga agaaaacttt agccttagga agtcattccc tcgtttcatc ctcttctttt
     1861 tattagcttc cctcatcacg acattgatga ccagtttggg agtttctgcc gatgttttct
     1921 attccctaaa aaccttatca aaattcttta tcgtgatggc tatggcagcg attggtttaa
     1981 acacaaactt ggttaaactg attaagacgg gcggtcaggc tatcctttta ggagctattt
     2041 gctgggtagc tatcaccctt gtcagtttag ccatgcaatt aagtttgggc atttggtaat
     2101 cagacacgag aaatcagttt gactgatttc tttttttgta tcttatttgt gtagaattgt
     2161 ctacatttta aagagaatag tgcattttaa aaacgttttc ctttgataaa ataaacctat
     2221 cgttacacca gttcagtaaa gacaactggt tgagataagc aattaccgtt tactcagcgg
     2281 tttttgttaa tagaggagga taggaatgaa acgaaaattt ctcattggga gtcacggcag
     2341 actagccagt ggtttgcaaa gctctattga cattttagca ggtatgggac aggcacttga
     2401 aaccattgat gcttatgttg atgatagtga ctacactagc cagattgatg actttatcgc
     2461 tggggtagca gcagatgagc agggcctcat ttttactgat ttgttaggcg gcagtgtgaa
     2521 tcagaaaatg gtaaccgctg taatgaacag tggcaaagac aatatctttt taatcacaaa
     2581 cagtaactta gccactttat tgtcgttggt gtttttaaaa ccaggcgaag cgcttactaa
     2641 agatgaaatt gtaaccgtta tcaatgaatc gcaagttcag ttagtggatt tggtccctga
     2701 gacaaattca gaagatgact tttttgatta atatcttaat atctaggagg aagacaaatg
     2761 attactcaaa ttcgtgttga cgaccgtttg attcacgggc aagtggcagt tgtatggacc
     2821 aaagagttaa atgcgccgct tttagtagtg gctaatgatg aagctgcaaa aaatgaaatc
     2881 acacaaatga cgcttaaaat ggctgtgcca aacggcatga aactgcttat tcgttcagtt
     2941 gaagactcga ttaagctctt taatgatcca cgcgcaactg acaagcggat ttttgtgatt
     3001 gtcaattctg ttaaagatgc ctgcgccatt gctaaagaag ttccagactt agaagctgtt
     3061 aatgtggcta atgtggggcg ttttgacaaa tcagacccag caagcaaagt caaagtgaca
     3121 ccaagtcttt tacttaaccc agaggaaatg gcagccgcaa aggaattagt cagtttacca
     3181 gaacttgatg tctttaacca agtcttacca tcaaatacca aggtccattt gagtcaatta
     3241 gtcaactaaa gagaggtaaa aaagtatgtt agtaccagca acaatggcag ctttagctgt
     3301 attgatttgt tttgggggaa attatttaac cggtcaaagc atgatggaaa gacccctagt
     3361 agttggactg gtcacaggtc ttcttttagg agatatgaag gtcggtatct taatgggggc
     3421 ctctctagaa gctcttttcc taggaaatgt gaatattggg ggtgttattg cagctgagcc
     3481 tgtaacagcg actgccatgg caacaacctt taccattatt tcacatattg accaaaaagc
     3541 agccatgacc ctagctgttc caattggaat gttggcagcc tttgtggtta tgtttttgaa
     3601 aaacgtcttc atgaatatct ttgctccaat ggttgataaa gctgcagcag ctaaccatca
     3661 aggtaaacta gtgatgctcc actatggcac ttggattatc tattacttaa tcattgcctc
     3721 tatttctttc attggtattt tagtaggtag tggacctgtt aatgcctttg tggaacacat
     3781 tcctcaaaat ctcatgaatg gcttgagtgc tgcgggaggc cttcttccag ctgtcggttt
     3841 tgccatgctg atgaaattat tgtggaccaa caaattagct gttttttacc tattgggctt
     3901 tgtcttaaca gcttatttga aattaccagc ggttgcagtt gctgccctag gagcagttat
     3961 ttgcgtcatt agttcccaac gtgatctaga attagacgca attactagag gtgcaattag
     4021 taaacaaaca acctttgact ctaaagaatc agaagaggag gacttcttcg catgacatca
     4081 caagataatt tgactaaaga agaccgtaaa atgcttcgct cagtcttttg gcgctcatgg
     4141 acgatgaatg ctagtcgtac tggggcaaca caataccacg cagtaggggt tatttacact
     4201 ttactaccag tcatcaatcg tttttataag actgataagg ataaagcaga ggcactggtc
     4261 cgtcatacaa catggttcaa tgccaccatg cacatcaata actttatcat gggtcttgtg
     4321 gcatcgatgg aaaagaaaaa cagtgaagat cctgattttg atgctagtgc tatcaccgct
     4381 gttaaggctt cgttgatggg acctatatct ggagttggag attccttctt ctggggaatt
     4441 ttaagggtta ttgcggcagg tatcgggatt tccttggcaa gtgcaggctc agccatggga
     4501 gctgttgtct tcttactctt gtacaatatt cctgctttta ttattcacta ctatagcctt
     4561 tatggtggtt attctgtagg tgcaggattt atcaaaaaac tttacgaatc tggtggtata
     4621 aaaatcgtca ctaaaacctc aagtatgctt gggttaatga tggtaggctc aatgactgct
     4681 tcaaatgtaa aatttaaaac gattcttaca gttgctgcga aaggtgccaa agaagcagct
     4741 tctattcaag attaccttga ccaattgttt attggtattg taccattaat ggtaacacta
     4801 gcagcttttt ggcttctacg aaagaaagtg aatatcaact ggattatgtt tggtatcatg
     4861 ttccttggca ttatccttgg acttttaggt atttgctaat aatctcctag caataaaggt
     4921 aagtaagaca agttttcttg ttttgcttac ctttttcctt ttaagatgat gagacttgtt
     4981 ttgatgaaaa acgtagtagc attaagaaat ttgttataat gaagggagct taagatgcga
     5041 ggtgaacagg tggaagaaca ttttaaaaaa caattacaag atgatatttc tagacatttt
     5101 tcgtaccaat cgttaatgtt atcattgttg ctaattggtc tttttattat tttttcatta
     5161 gcgccacaac aattaggcct ctatcgtgat atcaatgcca ctgcaacccg ttatcaccgt
     5221 ttgattagca aacaagaagc cttgctggat gacttaggga aaaatagctt actacctttt
     5281 ttaaataaaa acctcagcac tgctgattta agcaagcact attttcattt gcgccatagc
     5341 agccaaacgt caccagaact tttactattt tcacctaatc aaggcctttt atttgctagt
     5401 aacccacatt taggaaatgc ttttagtaaa tctgtttata ttcaagaagt cttgagagca
     5461 gctcatcctc caaaaacctt gtttaaagtt gctatggata gtgaagatgg tcactacttg
     5521 atgatcatta agccaatgat tgatcaaaac caactaaagg gatatgcttt tttagtgatg
     5581 agtggcaaag attttcttca tcctacaaaa acattgacgt cagagttggt cattgctgat
     5641 aagctggaca acacgtttac gttttccaat cgtgagttta tagcatctag tctagataag
     5701 atcaatagcc agtatttaca ccattatttt gtttttcaag ataatcgagc ctttatcaca
     5761 agaaaggttg ccttacaagg aggtctttgg ctttacatgt ataggccctt gattccaatg
     5821 gtatcggtga tgttattttc acttatttca tcagctgtta tctttgtgat cttgcaacgt
     5881 aaatcaagtg gtttagctaa ccgaattgca gctaaaaatt caagagcaat caatcaaatg
     5941 gttagagata tgagtgcgat ctctcggcaa gaaaaaagac gtattgacct tgagagtcaa
     6001 gatgaatttc aatatttatc tgatcaaatc aatcaaatgg tagagcgatt gcaacagtta
     6061 catgataaaa cgttagattt ggaaactcaa aaattattat ttgaaaaacg gatgttagaa
     6121 gctcaattca atccgcattt cctctacaat acgctagaaa ccattttgat tacgagccat
     6181 tatgattctg ccctaacaga aaaaattgtt atccaattga caaaattgtt gcggtatagt
     6241 ctcacggatt ctagcaaacc tgtcttgctc aaagatgatt taagtgtcat cgagtcttat
     6301 ttagtgatta atcaggtgcg gtttgaagaa ttgcaatata gcattaacct atccccagac
     6361 cttgatagtc ttgcagtgcc taaattgttc ttgttacctt tgatagaaaa tgccatcaaa
     6421 tatggcttga aagaacgaca cgatgtcaag attaacattg cttgttatta tcaagatgac
     6481 cacattattt tttctgtgcg agataatggt tcgggaattg atgctcatca ccaaaaagtg
     6541 attcgagagc aattggaagc tggagagtca caccatgggt taattaactc ttatcgtcga
     6601 cttaagtatc atttttcaga agtatccttg gtttttgatc aaggtgataa acagtttaat
     6661 gttagctacc atgttaagga gtagtctatg tacaaattag tcattattga agatgaacat
     6721 attattagga aatggttgcg atacgctatt gattataaag ctttagatat tttggtcatt
     6781 ggcgaggcta aagatggcaa agaaggagct gttttaatca aagagagtca accagatatc
     6841 gttttaaccg atattaacat gcccatcatg acagcttttg acatgtttga atcaacaaaa
     6901 gatcaaactt acgccaaaat tattttatct ggctatgccg attttccaaa tgcaaggtct
     6961 gccatacact acggtgtact tgaattttta acaaaaccga ttgaaaaagc agctctttgg
     7021 gaatgtcttc aaaccattat tgctaaaata gaaaagcaaa aggggtctaa tcaaaaaaca
     7081 gatgcttgcg tctatattcc cttaccccag atgactgatc agattcctga agtagtcaaa
     7141 gatattttgg agtgggtaca tgttcatttt caagacaaga tcagcacgag ccgcctagct
     7201 catgacttag ggtatagtga gagttatatc tatcaaaata tcaaaaagca tcttcagatg
     7261 cctttaagtg attacattaa tcaatatcgg attaatcagg caattcaatt gatgcaacaa
     7321 gaaccagatt taatggtata tgaaatagca caagctgtag gtatttatga ctatcgctat
     7381 tttgataggg tttttaaaaa gtatctagga caaactgtaa aggcttttaa agaagagcat
     7441 tttatgaaag ataccgatag gagtaagcca tgttaaaact caaacgcaaa tggctattaa
     7501 gctttttgtt agtaataatt attctagcaa tcgttaacgt tgcaatgtgt atattatcat
     7561 cgtcaaaaaa agatagtgca aaagaattag ttatcttgac tcctaatagc caaactattt
     7621 taacagggac tattccagcc tttgaggaaa agtatggggt taaagtaaga ttaatccaag
     7681 gtgggacggg ccaacttatt gatcaattag gtcgaaaaga taagccatta aacgctgata
     7741 ttttctttgg gggcaattac actcaatttg aaagccataa agatttattt gaatcctatg
     7801 tttctccgca ggtttctact gtcatttcag attaccaatt gcctagtcat cgtgcaaccc
     7861 catatacgat caatggcagt gtactgattg ttaataacga attagcaaga ggacttcata
     7921 ttaccagtta tgaggatttg ctacaaccag ctttaaaagg caaaattgct tttgctgacc
     7981 caaatagctc atctagcgct ttttcccaat taacaaacat cttactggct aaaggaggct
     8041 atacgagctc agaagcttgg gagtatgtga aacgtttatt actgtctatg aattctatca
     8101 gagcaacaag ttcttcagat gtttacgaat ctgttgcaga aggtaaaatg attgttggtt
     8161 tgacctatga agatccttgc atcaatctgc aaaaaagcgg tgcaaacgtt tcgattgttt
     8221 atcctgatga ggggacagta tttgttccgt catcagtcgc tattatcaaa aaagcaaagg
     8281 caatgaaaga agctaagcaa tttattaatt ttattttatc atcagatgta caaaatgcct
     8341 ttgggcagtc aactagtaat agacctatcc gacgagatgc tcaaacaagt catgaaatga
     8401 aaccattaga tgaaattatt actttaaaag aagattacgg atatgttact agacataaga
     8461 aaaaaatatt gaatacctat aatcgactac atgaagcatt agaaagagga aagtagactc
     8521 taggcttgtt gttgctatac tagtagtgtt acaaaatagc gtagtcattt tttgaaatcg
     8581 atttcataat ctggtagact aaggttatca cgaaaaggag gctatatgtg atgacttatc
     8641 aaactattta cccttataca aatgaagtcc ttcatacatt tgataatatg accgatcaag
     8701 gtttggcaga tgtccttgaa agagctcacc ttctctataa aaaatggcgc aaggaagatc
     8761 atttagaaga acgtaaagcc cagcttcatc aagtggctaa tattcttcgc cgtgaccgcg
     8821 ataaatacgc tgaaatcatg accaaagaca tgggaaaatt gttcacagaa gcccaaggtg
     8881 aagtagatct ttgtgccgat attgctgatt actacgctga taaggcagat gaattcttga
     8941 tgtctatgcc actagaaacg gattcaggtc aagcttacta tttgaaacaa tcaactggtg
     9001 ttatcctagc tgttgagcct tggaattttc cttactatca aatcatgcgg gtctttgcgc
     9061 caaactttat tgttggaaac ccaatggttt taaaacacgc gtccatttgc ccacgctctg
     9121 cccaatcctt tgaagaatta gttcttgaag ctggtgctga agcaggtagt attaccaatt
     9181 tgtttatttc ttatgcccaa gtatcacaag tgattgctga taaacgtgtg gttggtgtct
     9241 gcttgacagg ttccgaacgt ggaggagcta gcattgcaga agaagctggt aaaaacttga
     9301 aaaaaacaac ccttgaattg ggtggagatg atgcctttat tatccttgat gacgcggatt
     9361 gggatcaatt agagaaggtg ctttacttct ctcgtctcta caatgcaggt caagtatgta
     9421 cctcatcgaa acgttttatc gtgcttgaca aagactatga ccgtttcaaa gaattattaa
     9481 caaaagtctt caaaacagct aaatggggtg acccaatgga tcccgaaacg acgttggcgc
     9541 cattatcatc agctcaagct aaagcagatg ttcttgacca aattaagttg gccttggatc
     9601 atggtgcgga gttggtttat ggtggtgaag cgattgatca tccaggtcat tttgtcatgc
     9661 caaccattat tgctggcctc acaaaagaca accctattta ctatcaagaa atctttggcc
     9721 cagtcggtga aatctacaaa gtgtcttctg aagaagaagc gattgaagtg gcgaatgatt
     9781 ctaactatgg ccttggaggt actatcttta gtagcaatca agaacatgcg aaagccgtag
     9841 ctgctaaaat tgaaactggt atgtctttta tcaactcagg ttggacaagt cttccggaac
     9901 tcccatttgg cgggattaaa cattcaggct atggccgtga attgagtgag cttggcttta
     9961 catcttttgt gaatgaacac cttatctata ttccgaataa aacgaataat agcaatacta
    10021 aggtttgatc tagattgtta aaggggatct gctcgcctta ataaacaatc aaggcgttac
    10081 actcttcttt tttaaagtca aaattttaaa aatttgataa actagtaaca tgaacgaact
    10141 gattaaacat aaactagaac tcttaccaga cagccctggc tgttacttac ataaagataa
    10201 agaaggaact attatctatg tcggtaaggc caagaatttg aaaaaacgcg tccggtccta
    10261 ttttcgtggg agccatgata ccaaaacaga gttactagta tctgagattg tagatttcga
    10321 atatattgta acagagtcag ataccgaagc gcttttgttg gaaattaact tgattcaaaa
    10381 aaatatgcct aagtacaaca tcaagttaaa agatgataaa tcttatccct ttctcaaaat
    10441 cacaaatgag tcttttcctc ggttagtgat tacaagatat attaagaaaa atgatggatt
    10501 gtactttggg ccctacccag attcttacac tgctaatgaa gttaaaaagt tattagatag
    10561 gatttttcca tttaaaaagt gtaaaaatcc tatcaataag gtctgttttt attaccattt
    10621 aggccagtgc tgtgctcata ccatttgtca tacagacaag gcctattggg atcgtttaat
    10681 tgatgatgtt aagcactttt taaatggtaa agatgacaaa attattgaag atcttcgttc
    10741 taagatgtta gcagcttctg aagaaatggc atttgaacgt gccgctgaat atcgagattt
    10801 gatttcaggt attgccacca tgcgcaccaa gcagcgggtg atgagcaagg atttgcaaga
    10861 tagagatatc tttggctatt atgttgataa gggatggatg tgtgtccaag ttttctttgt
    10921 gcgtcaaggg aaattaattc agcgtgatgt taaccttttt ccctattata acgatgcaga
    10981 agaagatttc ttaacttata tggggcaatt ttaccaagat aaacagcatt tcatccctaa
    11041 agaagtcttt attccagaag ctattgatga agaactggta gccgctattg tgccaaccaa
    11101 aatcatcaaa cccaaacgcg gtgaaaaaaa acaactggta gctttggcta ctaagaatgc
    11161 tcgtgttagt ctgcaacaaa aatttgattt attagaaaaa gatatcaaaa aaacgagtgg
    11221 tgctatcgaa aatttaggtc agttacttag gattgacaag cctgtgcgca ttgaagcctt
    11281 tgataattct aacattcaag ggacaagtcc agttgcggct atggttgttt ttgttgatgg
    11341 caaacctagt aagaaagatt atcgtaaatt taagattaaa acagtggtgg gaccagatga
    11401 ttatgccagt atgagagaag tgctttttcg aaggtacagt cgggtgaaaa aggagggact
    11461 gcaagctcct aacttgatta ttgttgatgg aggcgttgga caagtcaatg tggccaaaga
    11521 tgtgatagaa aaacaacttg gactcactat tcctgttgcg ggacttcaaa aaaacgataa
    11581 gcaccagacc catgatttgc tttttggaaa cccacttgaa gttgtaccgt tgccgcgccg
    11641 ttctgaagaa tttttcttac tgcatcggat tcaagacgaa gtgcatcgct ttgcagttac
    11701 atttcataga caagtgcgac gtaaaaattc tttttcatca acattagatc atatttcagg
    11761 gcttggccca aagcgaaaac agttattact aagacacttt aaaaccataa cagcgattgc
    11821 atcagctacc tctgaggaga ttcaagcttt aggtatacct aaaacagtag ttgaagcaat
    11881 acagcaacag ataacagaca ataaaaatga tagatcgtct ccttaaataa gtgttatgtt
    11941 ttcagtactg atgaggtaaa aaggcgctac ttgttacgca cgacatttca gttcgttatt
    12001 ttgaaacttt cagaaagttg cgaagtgtag tgagtttatg attttaaaaa ctattttatg
    12061 gtaaaataaa atggtataaa aaaacagatt tagataggaa gttttgaaat gaaatttcta
    12121 gagttaaaca aaaaacgcca tgccattaag acctttaatg accagccagt tgactacgag
    12181 gatttgcgaa cagccattga gattgcaacc ttagcaccta gtgccaataa cattcaacct
    12241 tggaaatttg tagtcgttca agagaaaaaa gctgagttag caaaagggtt acctctagca
    12301 aataaagtgc aggttgaaca ggctcaatat gtagtggcgc tattttcaga cactgattta
    12361 gctttacgtt ctcgtaaaat tgcccgtatc ggtgtcaaat cgttaccaga cgacttaatt
    12421 ggttattata tggagacttt gccaccacgt tttgctgcct ttaatgaggt tcaaaccggt
    12481 gagtacttag ctattaatgc aggcattgtg gctatgaact tggtgttatc cttgacggat
    12541 caaaagattg cttccaatat tatccttggt tttgataagt caatgaccaa tgaaatttta
    12601 gacatcgatc cgcgttttcg tccagaatta ttgattactg ttggctatag tgacgagaaa
    12661 ccagaaccaa gttatcgttt gcctgttgat gaagtcatcg aaagaagata gagtcaggac
    12721 aattagttaa atgtaatgtc cagatgcgct acggagcgac cactattgtt agactgatac
    12781 tattttggct tattttaagt taaacattat ccctaaaacg aataaggaga gtataatgac
    12841 aaccattgat tttaaagcag aagttgacaa acgtaaagaa gctatgctag cagatttagt
    12901 tgacctatta cgcattaatt cagaacgcga tgacagattg gccgatgatc agcatccctt
    12961 tgggccaggc ccagttaagg ctttggagca tttcctcgca atggctgagc gtgatggcta
    13021 caaaacgcgt aatattgata actatgcagg tgactttgaa tttggtcaag gtgatgaagt
    13081 actaggaatc tttggtcacc ttgatgttgt gccagctggt agcggttggg atacagaccc
    13141 ttatgagcca gtgattaaag acgatcgcat ctatgcgcgt gggtcttcgg atgataaagg
    13201 accaaccatg gcgtgctact acgctctgaa aatcattaaa gaattgggtc ttcctgtgtc
    13261 taaaaaagtt cgtttcattg ttggtaccga tgaagaatct ggctgggggg atatggatta
    13321 ttactttgct cacaatggct tgaaaaatcc agactttggt ttctcaccag atgctgaatt
    13381 tccaattatc aatggtgaga aaggaaatat caccgaatac ctccatttcg ctggtgacaa
    13441 caagggcgct tttgtgcttc atcgcttcca aggtgggttg cgtgaaaaca tggtaccaga
    13501 atctgccaca gctgtcatta cggcaccgca tgaccttgat gtgctagaag cagctttgga
    13561 gcaattttta tcagaacatg gtgttaaagg ttctatgaag gctactgatg gtaaaattga
    13621 agtaactatt attggtaagt ctgctcacgg atcgactcca gaagcgggtg ttaatggtgc
    13681 caccttgttg gctaaattcc tgaatcaatt tacctttgaa ggggctgcta aggattattt
    13741 acatgtggca ggtgaggtgc ttcatgaaga ctttgcggca gaaaaactag gccttgctta
    13801 taccgatgac cgtatgggag ccctgagcat gaacgcaggt gttttcacct ttgatagtca
    13861 atcagctgac aataccatcg ccttgaattt ccgctatcca aaaggaactg atgcggcaac
    13921 cctaaaagca ggcttggaaa aattaccagg agtaattaag gtaagccttt ctgagcatga
    13981 acatacacct cattatgtgc caatggatga tgaattagta gctaccttac ttgctgttta
    14041 cgaaaaacaa acaggtctta aaggttacga acaagttatc ggcggaggaa cctttgggcg
    14101 cttgctagaa cgtggtgtgg cctttggagc gatgttccca ggtgatgaaa acactatgca
    14161 ccaagctaat gaatatatgc ctttagaaaa tatttatcgc tcagcagcta tttatgctga
    14221 agcaatctac gaattaatta aataagatgc ttatgacagc aaaaagagct ggaacactgt
    14281 tccagctctt ttgtgatgat tagagactgt tgttatttac caagacaaaa ttggctaaag
    14341 agttgggtaa tgagttcatc aggagcagca tcccctgtga tttctccgag aatttcccaa
    14401 gttctggtta aatcaacctg tagtaaatca actggcatgc caagcgccaa gccgtcattg
    14461 acagcttcta aactctggac tgccttttca atcaaagaaa tgtggcgggc atttgacagg
    14521 taagtggcat cttgctctac caaaccagcg ttgtcaaaga aaagctggtt gatacgatct
    14581 tcgattagat taatgttctg gttggttaaa acggaaatgg gaatgtagtc atctggtaat
    14641 tgctctaatt caatcttttg ttccaaatcc gttttattca acaatataat acggttactg
    14701 ccctgactga gatttaacaa agcccggtct tggtcagtca gtttttcaga agcattcagc
    14761 acaagaagaa caaggtcagc ttcttgaaga gcttttttag accgttcaac tccgatttgt
    14821 tcgaccagat catctgtctc acgaataccg gccgtatcga caagttttag aggaactccc
    14881 ttgatattaa cgtattcttc aatgacatct cgggtggttc ctgcaatatc agtcacaata
    14941 gccttgtctt ctcgcaacaa attattaagt aagcttgact taccgacgtt tggacgacca
    15001 ataatagctg ttgataagcc ctcacgcaga attttaccgc gtttagctgt tcgaaggaga
    15061 ttttccaaaa ggctttggaa ttcttgtgtt ttctcacgta gcagagcagt ggtcatttct
    15121 tccacatcgt cgtattcagg gtagtcaata ttaacttcga cttgagctaa ggtgttgaga
    15181 atttcttgtc gggtgtcatt gataagctgg gaaagggagc catccagttg cttgactgca
    15241 atcgtcatag ccttgtctgt tttggcacga ataatgtcca tgacagcctc agcttgagtc
    15301 aaatcaacac gaccatttaa gaaggcacgt ttggtgaatt cgccaggctc tgccattcta
    15361 gcgccttggc gaatcaatag ttggaagatt tcatttgtca cagcaatacc accgtgcgta
    15421 ttgatttcaa ccacattttc acgggtaaag gttttggggg ctagcatgac tgacaccata
    15481 acttcatcga taatagttcc tgtcttagga tcaatgatat ggccatagtt aatggtgtgt
    15541 gaggcgactt gctctaagtt ctttccctta aaaacagatt gtgcaatggc aagcgcatct
    15601 gtccctgata gacgaacaat gccaatagct ccttcaccaa gaggggttga aatggcggta
    15661 attgtatcaa attctttagt tatactcatg ccctctattt taaatcaagt cctagtagaa
    15721 agcaaggtat tattttgtat agaaaatagg actagcacca ttttgagttt agctaatact
    15781 aaaaaagaat aaatgtaaaa aaatcatttt tttaataatt tttattgaca atagtattat
    15841 aaaagaatat aatgatatag gttttgataa aaaactgacc taagacagca ggggagcatg
    15901 ctcataatat tcctgccgag gcacaaaacg tgattaaaga aaataacgta tttgtacttt
    15961 cgtgtctagg tttaggtgcg atttttttgt acctagccca aaaataaaaa cggaggtaaa
    16021 actaatgagt gaagcaatta ttgctaaaaa agctgaacaa gtcgaactta ttgctgagaa
    16081 aatgaaagca gcagcaagta tcgttgttgt tgattcacgt ggtcttacag ttgatcaaga
    16141 tactgttctt cgtcgttcac ttcgtgaaag tggcgttgag ttcaaagtta tcaaaaactc
    16201 aattttgact cgtgcagctg aaaaagcagg tcttgatgag ttgaaagatg tattcgtagg
    16261 accatctgca gtagcatttt ctaacgaaga tgttatcgca ccagctaaag ttatcaacga
    16321 ctttactaaa actgctgacg cacttgaaat caaaggtggt gcaatcgaag gcgctgtttc
    16381 ttcaaaagaa gaaatccaag cacttgcaac attgccaaac cgcgaaggaa tgctttctat
    16441 gcttctttct gtacttcaag ctccagtccg caacgttgca tacgctgtca aagctgttgc
    16501 agaaaacaaa gaaggcgctg cttaagacgt ctcagagtag cttaaggcta cgcttaacat
    16561 tttaaattaa ttatttggag gaaatcacaa tggcattgaa cattgaaaac attattgctg
    16621 aaattaaaga agcttcaatc cttgagctta acgatcttgt aaaagctatc gaagaagaat
    16681 ttggtgtaac tgcagctgct cctgtagctg ctgcagctgc tggtggtgct gaagaagctg
    16741 ctaaagattc attcgacgtt gaattgacat ctgctggcga caaaaaagtt ggcgttatca
    16801 aagctgttcg tgaaatcaca ggtcttggtc ttaaagaagc taaaggtctt gttgatggag
    16861 cacctgctaa cgttaaagaa ggcgttgctg ctgcagaagc tgaagaaatc aaagctaaac
    16921 ttgaagaagc tggagcaaca atcactctta aataagaagc agatagcaat ttgagagcga
    16981 aatcccgatt tatcagtctt ttagagttta tagcgatttg aagaaactga taaattgatt
    17041 tggtttcttg ccaaaaatcc tgcccaaaaa atctttggca ggatttttat tttctataaa
    17101 aattaagctg agtagagtgg ttattctatc tatatgtgtc tagtaataat ttttttatgt
    17161 gaacgagaac attttaataa gtgttctcat ttttttactt ttaggaggaa aatcatgcaa
    17221 atgaatgaac agtcatcacg acaaatggtg attgccatct atctcattta ttccaactca
    17281 aaatgatagt actccttggc tgttccgagt cgaaattgtt agtgattaag aaaacctacg
    17341 agactatggt ttgatcgatg aagtccaaca gtctcccagt gaaaaagggc gtttggctaa
    17401 taagatttat ttaggaaagt tggaacatga ttccacccca gtcttaagtt cagacggggc
    17461 cagtctcaaa aacagaccag ccccgtgtta aattcagccc ctagtgagac tgaaaagagt
    17521 gaaactaaag agagtaattt agtcattgag gacgaggagg aaagaaagga gtgcactagt
    17581 gtgaaaaaga ctgagggtca ctttatccgt caagttgatc aggtcaccaa atatgacaaa
    17641 gattatattt ggagtttggt tcattcccaa ttacgtgaag gtggtttatc acaagctgct
    17701 agtgacttag tcatgagcta ttttgaagaa cgctatgctt atgcgctgga acacatacgg
    17761 ttcgcaagaa cagctgaagc tattgcggaa tatgtcttta atggtgtctt atccgaatgg
    17821 accaagcaac taaggtgaca agaagcgaag tgaggtgagt aagatgtttt ggtggctatt
    17881 attaggtgtt tggggactaa ggacaatttg gttgattatt gaagttatca ctgcaccaga
    17941 aatggaagat tatagttgag taaggacgtt acataagcag taaggtcctt ttattttgtc
    18001 agaaaggaat gagagatatg aagtttttag atttgtttgc aggaattgga ggctttcgat
    18061 tgggtttaat taatcagtgc catgagtgta ttggcttttg tgagattgat aagtttgtga
    18121 ggcaatctta caaagccatc tatgagaccg aaggagaaat agaatttcat gacattagac
    18181 aagtcacaga ccaagacttt agaaaactta gagggcaagt ggatatcatc tgcggtggtt
    18241 tttcccttgt caagcatttt cactcgcagg cagacgactg ggatttgagg gcactaggag
    18301 aactctcttc tttgagatta ctcgagcgac caaacagata aaaatcatac ccataatcac
    18361 atccaatcag cgccattgac cgtaattcag ataaaaaatt gatatggaat tataccttgg
    18421 aacgaaatct ccgtatgatc tcagaccgta tttctaaaat ggcgggggca aaaattatcg
    18481 agaagcgtta ttcctaccgt gactatcaaa aatataggca gtctagtcat aaatttgaat
    18541 tgaaacaacg tctttatttt ttgattcagc agtcaaagtt ctttgatgat tttttagaaa
    18601 aagcagagta attacatgtt catattgatt ttagtcagaa gcatagcaga ttcatgatga
    18661 cggatcgagt aatgaaaaaa ccaattcgag gccgtcaact cagtaaacga gatttatatg
    18721 atgaagaatt ttttcgtaca cattttgcca agatagaaat tgaaagtcga ttagaatttt
    18781 tgttgaaccg tgccaattca ttagaggagc tactattaaa agcaaaagaa gtgaatctaa
    18841 ccattgactt aaaacaaaaa atgtaacttt tatcctagaa gaagatactc aaaagataag
    18901 tttaggtcat aaaaaaataa tcgataagaa attatatgat gtcaattttt tcaagattac
    18961 tttaaaaata aggaagtcgg tgtttcagat cgattagaaa gtctacagaa acagtaccat
    19021 gcttttcaag aagaacgaga taaagagaag gtatccactg aagagagtaa ggaagtcttc
    19081 aagaaataca aggggcaacg agatgccatc catgagtttg aagttgaact tgtggaacat
    19141 caaattgaga ggttaattgc tgaggacatt tatatcaagg tgtcttttgg tgtaaagcag
    19201 agtggtctta ttttcattcc taactaccaa ttggatatta aggaagaaga aaatcataaa
    19261 aaatataaag tctatatccg tgagaccgca caattcttca tttacaacaa ggaggcgtat
    19321 aaacttaatc gctatatgcg agggcgtgag ctcatttgcc agttaaccaa tgatagcaag
    19381 agtattccaa aaagaagacg acaaaccatt gatacactta agaaaaagat tgaagaaata
    19441 agtctcctca ttgagttaga tacggagaat aagccttatc aagatattaa agatgacatt
    19501 gttaaagata tggctcaatt agatttgacc attacaaagt tgcaggacca tattgctcat
    19561 ctcaataagg ttgcggaggt cttgcttaat ctgaacaaca acgatataga gaaccgccgt
    19621 ttggccagat atgactatgc caagatgaac ttgactgcag ctataaaaat agaagaagtt
    19681 gagaaagaga ttgaaacttc tcaaaatgaa cttaatatat ccatagatga gtatgaatat
    19741 ctagtaagaa ggttggaaaa gtttggagag atcttgagtg atagcaaaat tatcgatact
    19801 tctcgaaatg aaatacaatg ggagtaatta tgatataatt tgggtggtag caatttttat
    19861 atcagatatt aaaatctagt tgatgtttcg taaataacta tattaaagaa atgattcctg
    19921 ccgcttacat taagaatagt ttatttgtaa gtatttcatt atttaaaagg ggtaataatg
    19981 tataagattt tagccataga tgatgataaa gaaattctga agcttatgaa gactgctttg
    20041 gagattgaaa attatcatgt tataacctgt caagagatag aattaccaat agtttttgat
    20101 gattttaaag gatatgattt gatcttattg gatatcatga tgcctaatat aagtggaact
    20161 gagttttgtt ataaaattcg ggaagaagtt cattctccaa ttatttttgt tagcgcttta
    20221 gatggcgata atgaaattgt ccaagcttta aatatagggg gagacgattt tattgtgaaa
    20281 ccatttagct taaaacaatt cgtagctaaa gttaactctc atttgaagag agaagagaga
    20341 gcaaagataa agaatgaggc tgaggagaga gtgaagcgta gttttccacc tatagaaatc
    20401 tatctagagg aacgtatgtt atatattgat aaacagccgt tattcctgac ttatagagag
    20461 tacgaaattt tagaattact gtcacgtcat ccgtataaag ttttcacaaa agaagagata
    20521 tatgaacaag tatatagcga tgaagcttca gcattgtttc attctatttc agaatatatc
    20581 tatcagatta gaatgaaatt ttcaagtttt ggaattaatc caataaaaac tattcgcggg
    20641 attggttata aatgggatgt ttaaaaaata ttcaataaaa aatcgtgttt ggcgcgccgt
    20701 cgttgaaatt gtctttggag tttgtatcac tgttttaatg attgcgataa tatcgctttc
    20761 tttttcaaag ttaaatatag tgacatctca taatgtggga gaagaatttt atattaaaga
    20821 taaacagtca atcaaacagt tgaacaatta tatgaagaca ttgggattag attatgttgt
    20881 ttttgataga aaaa
//
LOCUS       DATTYN010000037        20838 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.37, whole genome shotgun sequence.
ACCESSION   DATTYN010000037 DATTYN010000000
VERSION     DATTYN010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20838
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.37"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..218
                     /locus_tag="VB649_001607"
     CDS             <1..218
                     /locus_tag="VB649_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEP1670543.1"
                     /translation="KEKLYTVEIPNPNREGRGHAKFVLERQGNKVFLVKRKSKDCYYN
                     KNSNHLTEQEIRKDFDWAWQFAKEVTE"
     gene            215..466
                     /locus_tag="VB649_001608"
     CDS             215..466
                     /locus_tag="VB649_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670544.1"
                     /translation="MKPRKYPYSGKIRIIKKELPRFVRLGDFAFNSNLVKHIDKIRQV
                     KPNETLIRFKIPKLFMTYEEETFKVRLRIDKVVKILNQY"
     gene            541..960
                     /locus_tag="VB649_001609"
     CDS             541..960
                     /locus_tag="VB649_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEP1670545.1"
                     /translation="MSKAKAILKDLRNLDLYIASLIRRRDKIEASLLSSPKWSSDKVN
                     GGIKRKQDDVYVELIATAKDIEKKTAEAIRKQRELQNLIDSLENTDSQTILSMVYIDK
                     MTRWQVIDELNCSESTYFRLLRVATKELNNLTVNDSD"
     gene            1067..1411
                     /locus_tag="VB649_001610"
     CDS             1067..1411
                     /locus_tag="VB649_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEP1670546.1"
                     /translation="MAQLRADKKGTHRVAFDRNKKKLLKVATVCGICGKPVDKSLKYP
                     HPLSAAIDHIVPIAKGGHPSALENLQLTHWQCNRQKSDKLFANQASNEPKTIGNRNLP
                     QSRDWSSFAFKK"
     gene            1560..1916
                     /locus_tag="VB649_001611"
     CDS             1560..1916
                     /locus_tag="VB649_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670547.1"
                     /translation="MKKKCLICKKNFQAKTNRTLYCSEECRKKGNREKQRKLMKQKRA
                     EQRKEKKKVLNPNTDVTEKPKKIRNLAQHYKKLKKEILANESEFGFTGITLIEGIDVH
                     EENFVDLVMQKIKEQK"
     gene            1913..3181
                     /locus_tag="VB649_001612"
     CDS             1913..3181
                     /locus_tag="VB649_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP1670548.1"
                     /translation="MNYMGMGYLRRKLALFKTGVDKRYRYYAMDDRDDTRSIVMPNNV
                     REMYRSVLEWTAKGVDSLADRIIFREFANDDFNAWEIFKANNPDIFFDTAIQSALIAS
                     CCFVYIMPGAEDGLPKMQVIEASKATGILDPTTFLLTEGYAILESDSNGNPTLEAYFT
                     DKDIWYYPKKGKPYNIKNPTGHPLLVPIIHRPDAVRPFGRSRITKAGMYHQKAAKRTL
                     ERAEVTAEFYSFPQKYVLGMDPDAEPMEKWRATVSTLLEISKDEDGDKPTVGQFTTAS
                     MSPFMEHLKMYASLFAGGSGLTLDDLGFPSDNPSSVEAIKAAHENLRAAGRKAQRSFA
                     SGFLNVAYIAVCLRDEFPYLRNQFMDTEIKWEPLFEADANMLTLVGDGAIKLNQAIPG
                     FMDADVIRDLTGVKGSDNPTPKATEVTTDG"
     gene            3174..4667
                     /locus_tag="VB649_001613"
     CDS             3174..4667
                     /locus_tag="VB649_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670549.1"
                     /translation="MADDVLPKILKSVQQDFEKHFGKSEVVAKAFADLKSKKATYKTV
                     NEFGIEVGKLLSLALTGSITSDKLPDGKMYYNIAKRLLDETMGRNYKLISGYAGDVQR
                     LLNENAQIGLKVQRPPLNRDKINGMVNRLDSENTFDDVKWLFGEPIVNFSQSIVDDTI
                     KANADLQYKTGMTPQVVRTESGNCCEWCREVVGTYSYPKVPKDVWRRHQRCRCTLDYD
                     PKNGKVQSAWSKIWRKKEKTQESIERVEKFKESALVESIKNDIAKLDMTKVGPSDIID
                     IGKRINYHFRVSEHIGDKEKLKEIFSNFREIGGEIPKNTWAKGSSKLVKDQLQEAFQN
                     YPTEWAAVPDGIGKKLKAIKRKRGYFDGYDEDLVIATNGTRKTTPYHEIGHMIELVNP
                     DLVRLEKAWVDKRTANEAEVRLKDIFPSSNYGIGEVTKKDDFISPYIGKYYSDAAEVF
                     TMGLQGIFVPEERFAKSFDKKTWKYDYKTINDDPEFLNFIIGLFVKV"
     gene            4673..4897
                     /locus_tag="VB649_001614"
     CDS             4673..4897
                     /locus_tag="VB649_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670550.1"
                     /translation="MEPKLHRQLRQKYDDAEKQYLEKFGEDSLDRVFFWEPDVYFDEW
                     KKVLPDATLELNKAINSGVAIDPDPENAIY"
     gene            4947..5126
                     /locus_tag="VB649_001615"
     CDS             4947..5126
                     /locus_tag="VB649_001615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670551.1"
                     /translation="MNKISLNVEMTWENKDEFQQIMNKVNETKEAYEKALEAAESFVP
                     KMSCATKLNKGEGNE"
     gene            5119..5385
                     /locus_tag="VB649_001616"
     CDS             5119..5385
                     /locus_tag="VB649_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670552.1"
                     /translation="MNKRIKKKRKLETAIMLLIAENALQAEAIKNQNKEIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRKWGK"
     gene            5387..5623
                     /locus_tag="VB649_001617"
                     /pseudo
     CDS             5387..5623
                     /locus_tag="VB649_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106704.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5705..7120
                     /locus_tag="VB649_001618"
     CDS             5705..7120
                     /locus_tag="VB649_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEP1670553.1"
                     /translation="MVTKTKTKLGNQRPTQSVNLHFAKSLAHEAINYYKKTGLSCYPW
                     QENMLIPIMAVDEDGLWVHQKYGYAIPRRNGKTEVVYIVELWALHKGLKILHTAHRIS
                     TSHASFEKVKKYLEMSGYVDGEDFISNKAKGQERIEFKASGAVIQFRTRTSNGGLGEG
                     FDLLIIDEAQEYTSEQESALKYTVTDSDNPMTIMCGTPPTMVSTGTVFEAYRKDCLKG
                     NKRYSGWAEWSVPEMVKINDVSSWYISNPSMGFHLNERKIEAELGEDEIDHNIQRLGY
                     WPSFNQKSVISEKEWAKLKVEQVPELKSKLFVGIKFGQDGNNVSLSIAARTSENKVFV
                     ETIDCLSVRNGTQWIINFLKSADIAKVVIDGASGQELLAQEMKDQGLKKPELPKVAEI
                     ITANMMWEQGIMQETICHSDQPSLTAVVTNCEKRQIGSNGGFGYKSLYDDRDISLMDS
                     ALLAHWICYTTKPKRKQRTSC"
     gene            7200..7661
                     /locus_tag="VB649_001619"
     CDS             7200..7661
                     /locus_tag="VB649_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEP1670554.1"
                     /translation="MSEFKVIETQEELDTIVKARIAREREKYQDYDQLKTRVEELETE
                     NSSLQTALNDAKSNTDSYTEEISTLKNQIADYETANLRTKVALQYGLPIDLADRLQGD
                     DEDGLKVDAERLASFIKPSQPQPPAKSNEPNIDSNADANYRALVQGLSTED"
     gene            7686..8597
                     /locus_tag="VB649_001620"
     CDS             7686..8597
                     /locus_tag="VB649_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEP1670555.1"
                     /translation="MGTETSKASLFDKHLVSDLINKVKGHSSLAKLSSQKPIPFNGSK
                     EFTFTLDSDIDVVAENGKKTHGGLSLEPVTIVPIKVEYGARLSDEFLYATEEEKIDIL
                     KAFNEGFAKKLARGIDLMAMHGINPRTKKASDVIGTNHFDSKVTQVVKFTESEDADAN
                     IEAAVNLIQGAEGVVTGLAMDTEFSTALAKVTNGEMGPKMYPELAWGADPDSINGLKS
                     SVNTTVGAGADEAESKDLVIIGDFESMFKWGYAKQIPMEIIKYGDPDNSGKDLKGYNQ
                     IYLRAEAYIGWGILDAKSFARVTKGEV"
     gene            8597..8797
                     /locus_tag="VB649_001621"
     CDS             8597..8797
                     /locus_tag="VB649_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670556.1"
                     /translation="MLYVNSKTGASFYSSVPVCGGDWTLVEQQTGEKAKTVAEIKRQL
                     DAAGIKYSSKAKKPELEALLPG"
     gene            8807..9229
                     /locus_tag="VB649_001622"
     CDS             8807..9229
                     /locus_tag="VB649_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage Gp19/Gp15/Gp42 family protein"
                     /protein_id="HEP1670557.1"
                     /translation="MGNFATTDDVILLWRPLSVDELKRANALLKVVSDTLRMEADKVG
                     KDLDKTMVDKPYFVNVIKSVTVDIVARTLMTSTQGEPMSQESQSALGYTWSGTYLVPG
                     GGLFIKDNELKRLGLKKQRYGGIELYGEIKRDNDYFDR"
     gene            9189..9527
                     /locus_tag="VB649_001623"
     CDS             9189..9527
                     /locus_tag="VB649_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670558.1"
                     /translation="MGKLRGITITLIDKVTIDIDPFGNPIKKDKEISVDNVLVSPATS
                     DDITSQLSLSGKKAVYTLAIPKGDNHDWGDKEVRFFGKKWRTVGIPLEGIEELIPLDW
                     NKKVMVERYE"
     gene            9520..9756
                     /locus_tag="VB649_001624"
     CDS             9520..9756
                     /locus_tag="VB649_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670559.1"
                     /translation="MSKFKFKLNRAGVAELMKSSEMQQVLTTKATAIRERCGDGYVQD
                     IHVGKNRANAMVSAKTIKAKKDNSKNNTLLKAVR"
     gene            9757..10092
                     /locus_tag="VB649_001625"
     CDS             9757..10092
                     /locus_tag="VB649_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670560.1"
                     /translation="MIEVIIKKYLDEHLDVPSFFEHQKDEPTRFVILEKTSGAKKNHI
                     LSSTFAFQSYGKSMYEAALLNEQVKQVVEQLEGLPEIAGVHLNADYNFTDTETKRYRY
                     QTVFDINHY"
     gene            10108..10683
                     /locus_tag="VB649_001626"
     CDS             10108..10683
                     /locus_tag="VB649_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003693359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP1670561.1"
                     /translation="MANDTKNVTSAKPKAGGAIYTAPLGTKLPTDAVTELDKAFKGLG
                     YVSEDGVTNEDTRSSENIKAWGGDVVGAVQTEKEDKFTYKLIESLNVEVLKEVYGSSN
                     VTGDLDKGIHIKSNSKELEAHAIVVDMIMNGGILKRIVLPNAKVDEVGEIVYVDGEVV
                     GYETTLKCFPDENGDTHHEYIVKPRARSLEM"
     gene            10694..10957
                     /locus_tag="VB649_001627"
     CDS             10694..10957
                     /locus_tag="VB649_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670562.1"
                     /translation="MEILKGKTTSGFEYEIPKKRLKNFELVEAIAEEETDPTAVVKIV
                     NLLLGDAAKSLKEHVRDADGIVDVEAIGVEIKEIFESQKDLKN"
     gene            10972..11343
                     /locus_tag="VB649_001628"
     CDS             10972..11343
                     /locus_tag="VB649_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5361 domain-containing protein"
                     /protein_id="HEP1670563.1"
                     /translation="MIVKDDDALTCDLAETYGIYDYKQLPAYQVAVFAVGLRSNSRIK
                     MALSGETEALDTVLLAGIYDNTNLLFWSKTKDGQSGQNKPKSMVEAISGSKSQKANEV
                     ISFASGEDFANARKQLLGGDG"
     gene            11343..13700
                     /locus_tag="VB649_001629"
     CDS             11343..13700
                     /locus_tag="VB649_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670564.1"
                     /translation="MATELGQAYVQIMPSARGISGAISKQLDPEARSAGLSAGSLIGG
                     NLVKMIGGAIAAAGIGKMISSALSAGADLQQSFGGIDTLYKGAETAVKGFAKEAYKAG
                     ISANTYAEQAVSMGASLKQSLGGDAVAAAKAANMAIMDMADNSAKMGTDITSIQMAYQ
                     GFAKQNYTMLDNLRLGYGGTKEEMKRLLSDAEKLPAAMGKKFDLSNYADVVEAIHLVQ
                     DNMGIAGVAAEEAKTTFSGSLAAMKSSFTNVLAGLSLGDDIRPALRRLAETTSNFLFG
                     NFIPMVANIFKGLPSAIGTFIGAATPIIASQFKGLMSSLGISIDLSPITAKFAQIGQN
                     LQPVFDGLKTAFGQLPSFFTSIGDAVAPVIDTIISGLARLDFSGFEALISAILPAIQT
                     GFQTFMSIVGPAISQLVNSFVNLWNACQPLVTILSSALMPAFQILGAFLGGVLQGILG
                     SISFAFDALKVVIEFLTPIIDWLVQGFNAISPALQTVAQWVGNVIGIFTSLGASGQGL
                     SSMLSSAWGNIQTVVSTAKNMITLAIDGIKLVFSNLGNAGNILKGLLSAAWSAMQNAV
                     VIAKGIINSAISAIKTAFSSFGNLVSSVSGTIKSVIGSLKNAFYSLASIDLVGAGRAI
                     MQGFLNGLKSMWGAITGFVGGIADWIRKHKGPISYDRVLLKPAGKVIMQGFNNSLMDG
                     FKEVKSNVSGMADDLAGTMTGKSLSLGIDAKPSVTADDLLSSNISAKTTLDSGTNDLS
                     LFFVRVLALLQDILDKDTDVYLDKEKVSAILYEEFAKIMAREGIA"
     gene            13697..14392
                     /locus_tag="VB649_001630"
     CDS             13697..14392
                     /locus_tag="VB649_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670565.1"
                     /translation="MIPKVIIDGFDTSTIPNCVLTGYDVGDVLSPRFVENEVYGMNGT
                     SRGLESYNESKPTLTWHLSTFDDAVNLVNHLDGLGKTIEFWHIPKSFYYYDCLSVKIN
                     AVTMKSWRVTLKLALYPFRYAKGISDVTIAGNGSINNPGNVFSEPKIVVEGTGKGTLT
                     IGKQVMELNLSGKATIECKHGQQCVYDTGGNVKNSIRIRGSFFEIQPGTQGIAVSGGI
                     TRLTISPRWRYKV"
     gene            14374..16353
                     /locus_tag="VB649_001631"
     CDS             14374..16353
                     /locus_tag="VB649_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEP1670566.1"
                     /translation="MEVQSLISIKDDNTPLVAAFEDEISQEANSDYKLSFKYPAKHDY
                     RPLIKKGIILEADDLHGTQLFRVFEITKRHGYINVYANQIADDLNGYAINSISVDRVQ
                     GMKVMSELAGSIKRDHPFSFFSDIDGRHTFNQSDVSVMDALANGKHSVMGQWGGELVR
                     DKYQVNLLKKAGKDTEALFMYKKNLKSYEETDTIKGLISILHLVAEVEEEHEGEAREA
                     SDGNIGHSESPKKKTIRATVESKLKDTHPIIVEKSIKVQDQDVKTEEDLLAYGKKYFE
                     STLCDIPGNSLKIDVTNNYEGNVRLFDTAIVFHELYDRDLRMQITGYKFAPMANRLKS
                     ISFGEIKTNLAKQISSQIDNKVAEATAQHDAAFEAKLQKQIENADRVFDTKEAKLRKE
                     IEDGIKKAEANAEVKVAEVNAKVLEAEKIAKEVDERLKKFLASADAKEQDFDKKLEEF
                     RKSLKDLEVDEKQIDDALAKAGFSKDSLADIKAKLEDTSETATVTANIVGSTGGTFYN
                     RNRLEGDTDKVITFEQGYIDIAHNGEGFEEGKTYTISFEATCELLKKVAVTLTQANNK
                     GVKLVLTPTKAKMEPETFTLTKDTEVISVYPLSYTAVLTGDWYKSKQIDLNALEGWEL
                     ALDMSYKDVVDGNNADLVLDWAENPDIIFDGNGGI"
     gene            16353..17375
                     /gene="hylP"
                     /locus_tag="VB649_001632"
     CDS             16353..17375
                     /gene="hylP"
                     /locus_tag="VB649_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase HylP"
                     /protein_id="HEP1670567.1"
                     /translation="MSGEVISARVRHKGMTKSEWESSDVILLESEIGFETDTGFARAG
                     DGHNRFSDLGYISPLDYNLLTNKPNIDGLATKVETAQKLQQKADKETVYTKAESKQEL
                     DKKLNLKGGVMTGQLKFKPAATVAYSSSTGGAVNIDLSSSRGAGVVVYSNNDASDGPL
                     MSLRTGKETFNQSALFVDYKGTTNAVNIAMRQPTTPNFSSALNITSGNENGSAMQIRG
                     IERALGTLKITHENPSANAKYDENAAALSIDIVGKRGASGNGTAAQGIFINSSAGTTG
                     KMLRIRNKNVDKFYVGPDGGFWSCANSTVAGNLTVNDPTSSKHAVTKDYVDKEIAKLK
                     ELIQKK"
     gene            17390..19174
                     /locus_tag="VB649_001633"
     CDS             17390..19174
                     /locus_tag="VB649_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670568.1"
                     /translation="MSRDPTYTINEHDLSFKDGRFYVTFRADKSSETVRLNSSCLGNT
                     VIKKLQVEDDNTMHDFVKPKVTTQQAFGLAQQVKELDLQLKDPNSDLWGRIKLNNKAM
                     LVEYGNKEMASAIAQSAEQILLQVKSIDDERYSKFEQTLNGIKQTVKSESVESARTQL
                     ASMFDSRISGLDGKYSRLSQTIDSLSSRLDDGIGNYSTLSQKVSGIDLRVSNAAKDVS
                     RLSQTAQGLQLQITNANQNYSSLSQTVGGLQTTVHDNQSNATSRINQLSDLISTKVTK
                     GDVETTIAQSYDKIALAIKDKLPKSKMTGNEIISAINLDRSGVKITGKNITLDGNSYI
                     SNAVIKNAHIANMDAGKINTGYLSANRIAAEAITGDKIKMDYAFFNKLTANEGYFRTL
                     FAKNIFTTSVQAVTTSASKITGGVLSATNGASRWDLNSANIDFNRDATINFNSKNNAL
                     VRKDGTHTAFVHFSNATPKGYTGSALYASIGITSSGDGVNSASSGRFAGLRSFRYATG
                     YNHTAAVDQTEIYGDNVLVVDDFNITRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGH
                     LANVGWNTAHSNFTSAVNRELNNYITKI"
     gene            19186..19614
                     /locus_tag="VB649_001634"
     CDS             19186..19614
                     /locus_tag="VB649_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEP1670569.1"
                     /translation="MQLTIKNKDLNTLYRVLDKIKITNMRANRGRAKLLAKVEGKLSE
                     YAKDEVDIIDQYVAKNDDGKWITDDKGNSKIEDTSKLAELNDFLDELASEPIVIKGGE
                     YSKRFIDFLEYLAESEDEFTAQEIIIVDSILEQYEGSKGE"
     gene            19617..20243
                     /locus_tag="VB649_001635"
     CDS             19617..20243
                     /locus_tag="VB649_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670570.1"
                     /translation="MKTLTLSGKPYPIHEGGKVVKTEIRLIGDNGLFIPIELIGDQTA
                     KGADDLIKEGLDAFVREYVTKYAVAESVQKVEELSLAQKEIEQNAEQAKVTAEAAEKQ
                     AKSLELVIAKSQKMANLQAIHLLTSGSKVEPDIYKGLLELIEPAKKGEYQAYDVFTVV
                     DESHEEQAGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVK"
     gene            20261..20536
                     /locus_tag="VB649_001636"
     CDS             20261..20536
                     /locus_tag="VB649_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670571.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLTDDVKDLKDMMRGEIK"
     gene            20533..20760
                     /locus_tag="VB649_001637"
     CDS             20533..20760
                     /locus_tag="VB649_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEP1670572.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKK"
BASE COUNT         7059 a         3473 c         4653 g         5653 t
ORIGIN      
        1 aaaaagaaaa gctttacact gttgaaattc cgaatccgaa tagggaaggc agaggtcacg
       61 ccaagtttgt gcttgaaaga caaggtaata aagttttttt ggtaaaacga aaatcaaagg
      121 attgctacta caataaaaac agcaatcacc tcacagaaca agaaatccgc aaagattttg
      181 attgggcttg gcaatttgcg aaagaggtga cggaatgaaa cctagaaagt atccgtattc
      241 aggaaagata agaattataa aaaaagaatt accaaggttt gtaagattgg gagattttgc
      301 ttttaatagc aacctagtta aacatattga taaaatcaga caagtaaaac caaatgaaac
      361 gctaattcgt ttcaaaatcc ctaagttgtt tatgacatat gaagaagaaa cttttaaagt
      421 aagacttcgg attgataaag tcgtaaaaat attgaaccaa tactaaacaa aaaagccagc
      481 tcacagctga ccattggtta ataattcgat aaatctatta taccaaaaag gagttaggaa
      541 gtgagcaaag ctaaggcaat tttaaaagac ttacgcaatt tagatttata tatcgctagt
      601 ttaattagac gtcgggataa gattgaggct tcgttgcttt ctagccctaa atggtcgtct
      661 gataaggtga atggtggtat aaaacgtaag caagatgatg tttacgtaga gttgattgca
      721 actgccaaag atattgaaaa gaagactgct gaagccataa gaaagcagag agagcttcaa
      781 aacctaattg atagcttaga aaatacagac agtcaaacaa ttttaagcat ggtctatatt
      841 gataagatga ctagatggca agtgattgat gagttaaatt gcagcgaaag cacctatttc
      901 agactgttaa gagttgccac aaaggagtta aacaatctga cagtaaatga cagtgattga
      961 cagtgaataa cagtgcatga cagttttaaa gtgataatat agtattatca agaaatgagg
     1021 gacaggtaca aaaatacccc ctcttttaaa tttagaaagg ccccctatgg ctcaattaag
     1081 agcggataag aaaggtaccc accgggtagc atttgacaga aataaaaaga agttactaaa
     1141 ggtagccact gtctgtggta tctgtggcaa gccagtggac aagtctctta agtatccaca
     1201 tccattaagc gcagcaatag atcatatagt tcctatcgca aaaggtggtc atccatcagc
     1261 gcttgagaac ttacagttaa ctcactggca gtgcaatagg cagaagtctg ataagttgtt
     1321 tgctaaccaa gcaagcaacg agccaaagac aattggcaac agaaaccttc ctcaaagtcg
     1381 agactggtca tcttttgcat ttaaaaagtg attttaggca aatatattga tttatgctaa
     1441 aagctcttag aagcgaaatg gggggtatct ccctacccgg tcggtcggcc gagcttcacg
     1501 ccgtcactgt acattttttc tcacgttagg atttagaaaa ttttggaggt tgaatttttt
     1561 tgaaaaagaa atgcttaatt tgcaaaaaaa acttccaagc aaaaaccaat agaactttat
     1621 attgctctga agaatgccgt aagaaaggca atcgtgagaa acaacgtaaa ttgatgaaac
     1681 aaaaacgggc tgaacagagg aaagaaaaaa agaaagtcct aaatcctaac acagatgtga
     1741 cagaaaagcc taaaaaaata cgtaatttag cgcagcacta taaaaaacta aaaaaggaaa
     1801 ttttggcaaa tgaatctgaa tttggtttta ctggaataac acttattgaa ggaatagatg
     1861 tacatgaaga aaactttgta gatttagtca tgcaaaaaat aaaggagcag aaatgaatta
     1921 tatgggtatg ggctatcttc gtaggaagtt agctcttttt aaaactggag ttgataaaag
     1981 atatcgttat tatgccatgg atgacagaga cgacacacga agtattgtca tgccaaataa
     2041 tgtgcgtgaa atgtacaggt ctgtgttaga atggaccgct aaaggggttg atagccttgc
     2101 ggaccgtatt attttcaggg agtttgccaa cgatgatttt aatgcttggg aaatttttaa
     2161 agcgaataac cctgatatct tttttgatac agccatacag tcagcattaa ttgcatcttg
     2221 ttgctttgtg tacatcatgc caggagcgga agacggctta cctaaaatgc aagttatcga
     2281 agctagtaaa gcgacgggga tacttgaccc aactacattt ttattaacag agggttatgc
     2341 aattttagag tctgactcaa acggtaatcc tacgttagag gcctatttca cagacaaaga
     2401 catctggtat tatccaaaaa aagggaaacc atataatatt aaaaatccaa caggtcaccc
     2461 cttgcttgta cctatcattc acagaccaga cgcagttaga ccatttggtc gcagtcgcat
     2521 taccaaggct ggaatgtatc atcaaaaggc agcgaagaga acgcttgaga gagcagaggt
     2581 tacggctgag ttttactcat tcccacaaaa atatgttttg ggaatggatc cagacgctga
     2641 accgatggaa aagtggcgtg ccacggtatc cacattgttg gaaatctcaa aagatgaaga
     2701 cggagataag ccaactgttg gtcagtttac tacagccagt atgtctcctt tcatggagca
     2761 tttaaaaatg tatgcttccc tattcgctgg tggttctgga ctcactcttg atgatcttgg
     2821 ttttccatct gacaatccat catcagtaga agctattaaa gcagcgcatg aaaatttaag
     2881 agcagcagga cgtaaagctc aacgctcttt tgcttctgga tttctaaatg tggcgtatat
     2941 tgctgtttgt ttaagggatg agtttcctta tttacgcaat cagttcatgg atactgaaat
     3001 taaatgggaa cctctttttg aagctgatgc aaatatgctt actttagtcg gtgatggcgc
     3061 tattaagctt aatcaagcta ttcctggttt catggatgca gatgttatcc gtgacttaac
     3121 tggggtaaaa ggttctgaca atccaactcc aaaagcgacg gaggtgacaa ctgatggctg
     3181 atgatgtctt acctaagatt ttaaaatcag ttcaacagga ttttgaaaag cattttggta
     3241 aaagcgaggt cgttgctaag gcttttgcag atttgaagtc taaaaaagca acatataaaa
     3301 cagtcaacga gtttggtatt gaagttggaa aacttttatc tttggctctg acaggctcta
     3361 ttacctcgga taaattacca gacggtaaaa tgtattacaa tatcgctaag cgtctcttag
     3421 atgagactat gggacggaat tacaaattga tttcaggtta tgctggtgat gttcagcggc
     3481 ttttaaatga gaatgctcag attggtctaa aggtgcaacg tccaccgcta aatcgagaca
     3541 agattaacgg gatggtaaat cgtttggata gcgagaatac atttgatgat gtaaaatggc
     3601 tgtttggtga accgattgtt aatttttcgc agtccattgt ggatgatacc atcaaggcaa
     3661 atgcggattt acaatataaa acaggtatga cgccacaggt tgtcagaaca gaaagtggca
     3721 actgttgtga atggtgtcgt gaggttgttg gcacttatag ttatccaaaa gtccctaagg
     3781 acgtatggag aagacatcag cggtgtcgat gtacgcttga ctatgacccg aagaatggta
     3841 aagttcagag tgcttggagt aaaatctggc gaaagaaaga aaaaactcaa gaatctatag
     3901 aaagggttga aaaatttaag gaaagtgctc tagtagaatc tatcaaaaat gatatcgcta
     3961 agttagatat gacaaaggtt ggtccgagtg atataattga tatagggaaa cgtatcaatt
     4021 atcactttag agtttcagaa catataggag ataaagagaa attaaaagaa attttctcaa
     4081 attttcgtga aatcggtgga gaaataccta aaaatacttg ggcaaaaggt tcatctaaac
     4141 ttgttaaaga ccagttacaa gaggcttttc aaaattatcc aactgagtgg gcagctgttc
     4201 cggacggtat tggtaaaaaa ctaaaagcta taaaaaggaa gcgcggttac ttcgatggat
     4261 atgatgaaga tttagttatt gctacaaatg gaacaagaaa aacaacacct taccatgaga
     4321 taggacatat gattgaactg gttaatcctg atttagtaag attagagaaa gcctgggtag
     4381 ataaaagaac tgctaatgaa gctgaggttc gcttgaaaga tatttttcca agttcaaatt
     4441 atggtattgg ggaagttact aagaaagatg actttatatc accatatatt ggtaaatact
     4501 acagcgatgc agctgaagtt ttcactatgg gattacaagg tatttttgtt cctgaagaac
     4561 gatttgctaa gtcctttgac aaaaaaacat ggaaatatga ctacaagaca atcaatgacg
     4621 accctgaatt tttgaatttt attattggat tatttgtgaa agtgtgataa atatggaacc
     4681 aaaattacat cggcaactgc gtcaaaaata tgacgacgct gaaaaacaat atcttgaaaa
     4741 gtttggagaa gactcgcttg atagagtatt tttttgggag ccagacgttt actttgatga
     4801 gtggaaaaag gttctaccag atgcaacact ggaattaaac aaagctatta atagcggggt
     4861 ggcgattgat ccagatccag aaaacgcaat atattaagca cctagagcaa tctggtgctt
     4921 ttcttatgcc caaaaaggag aaaaatatga ataaaatatc attaaatgtc gaaatgactt
     4981 gggaaaacaa agacgaattt caacaaatca tgaataaagt caatgaaaca aaagaagctt
     5041 acgaaaaagc cttagaagct gcggaaagtt ttgtccctaa aatgtcgtgt gcaacaaagt
     5101 taaataaagg agaaggtaat gaataaacgt atcaagaaaa aacgtaaatt ggaaacagct
     5161 atcatgctat tgattgcaga aaatgccttg caggctgaag caattaaaaa tcaaaacaaa
     5221 gaaatcatgg agttgaaatc aattgttcag cggaacgctc tggcaacaaa cgaagagtta
     5281 gcgactgtta aagctgctac tttagataac caatcagtta tcaaggcaat cggtgacacg
     5341 gttgactaca tcaagaaaaa ctacaaacgt aagtggggga agtgatatga aatatcgtaa
     5401 gaaaccggtc gtagttgaag caattcaatt tacgggtaca aactatgaaa aaatcaaaga
     5461 gtttattggt taaaatacct tatgttcgac tttgagtatt gtaatcccca ctcttgaagg
     5521 cgacatggtc gctcaaaaaa gcgactacat catcaaaggc atcgctggtg aattttattc
     5581 atgtaaacct gatgtttttg aacagactta tgaatcaact taaaccaaag tcgtagcaat
     5641 acggcttttt attgtgccct gtcgcatggc taaaaactag gcagtacgat tgaaaggaat
     5701 aagtatggtt actaagacga aaacaaagct tggcaatcag cgacctactc aatcggtaaa
     5761 tttacatttt gctaaatctc tagcgcatga agctattaat tactacaaaa aaacagggct
     5821 aagctgctat ccatggcaag aaaatatgct tataccaatt atggccgtcg atgaagatgg
     5881 cttatgggtg catcaaaagt atggatatgc tattccacgg cgtaatggta agacggaagt
     5941 agtctatatt gttgagctgt gggctttgca taaaggttta aaaatcctac atactgccca
     6001 tcgcatcagc acatctcacg catcatttga gaaggtgaaa aaataccttg agatgtcagg
     6061 ttatgttgat ggagaagact ttatatcaaa taaagccaag ggtcaagagc gtatagagtt
     6121 caaagccagc ggcgctgtta tccagttccg aactaggaca tcaaacggtg gacttggtga
     6181 gggatttgac ttacttatca ttgacgaggc acaagaatac acatctgagc aagaatcagc
     6241 attgaagtac acagttactg atagtgataa tccaatgact attatgtgtg gaacgccgcc
     6301 aacgatggta tctactggta cagtatttga agcatatcgg aaagattgct taaaaggcaa
     6361 taagcgttat tctggttggg ctgaatggtc agttcctgag atggttaaga ttaacgatgt
     6421 atcttcctgg tatatttcca acccatctat gggattccac ctcaacgaga ggaaaatcga
     6481 agctgaatta ggtgaagatg agattgatca caacatccaa cgcttaggtt attggccatc
     6541 ctttaaccaa aaatcagtta tatccgaaaa agaatgggca aaactcaaag ttgagcaagt
     6601 gccagaactc aaaagcaagc tttttgtcgg tatcaagttt ggtcaagatg gcaacaacgt
     6661 atcactatca attgcagcaa gaacatcaga aaataaggta tttgttgaga ctattgactg
     6721 tttatcggtc agaaatggaa ctcaatggat tattaatttt ttgaaatcgg ctgatatcgc
     6781 taaggttgtc attgatggtg caagtggtca agaattactt gctcaggaga tgaaagatca
     6841 aggtctaaag aaaccagaat tgcctaaagt tgctgaaatt atcacagcta acatgatgtg
     6901 ggagcagggg atcatgcagg aaaccatttg tcatagtgat cagccatctt tgacagcagt
     6961 agtcacaaac tgtgaaaaga ggcaaattgg ctctaatggt ggttttgggt ataaatcgct
     7021 ttatgatgat agagacatta gcttaatgga cagtgcattg cttgcgcact ggatttgtta
     7081 cacaacgaag ccaaaaagaa agcaaagaac cagctgttaa aaacgacatc cgaaagggtg
     7141 tttttttact gctaaaaaat ctaccgaact gccgggaaag caggagaaag gacgttaata
     7201 tgtcagaatt taaagttatt gaaacacaag aagagttgga cacgattgtg aaagctcgca
     7261 ttgctcgaga acgtgagaaa tatcaagatt acgaccaact gaaaactcgt gttgaagaac
     7321 tagaaaccga aaacagcagc ttacaaactg ctttgaatga tgctaaatca aacactgata
     7381 gctatacgga agagattagc accctgaaga atcaaattgc cgattatgag acggcaaatt
     7441 tacggacaaa ggtagcgtta cagtatggct taccaattga tttagctgat cgtttgcaag
     7501 gagatgatga agatggactc aaagtagatg cagaacgctt agcatcgttt attaagccat
     7561 cccaaccaca accgccagca aaatcaaacg aaccaaatat cgatagtaat gcagacgcaa
     7621 attacagagc gttagtgcaa ggattaagta cagaagatta gaagattaat taaaggagaa
     7681 aaaatatggg aacagaaaca tcaaaagcga gcttatttga caaacattta gtatcagatc
     7741 ttatcaataa agttaagggg catagctcac tagctaaact atctagccaa aaacctattc
     7801 cgtttaacgg atctaaagaa tttacgttta cattagattc tgatattgat gtggttgctg
     7861 aaaacggtaa aaaaacacac ggtggcttat cgctagagcc tgttactatc gtaccaatca
     7921 aggttgagta tggcgctcgt ctttctgatg aatttttata tgcaacagaa gaggaaaaga
     7981 ttgatatttt gaaagctttt aacgaagggt ttgcgaaaaa actcgctcgt ggtattgacc
     8041 taatggcgat gcatggtatc aatccacgta caaaaaaagc gtctgacgtt atcggcacaa
     8101 atcactttga tagtaaagtg acgcaagtgg ttaaatttac agagagcgaa gacgctgatg
     8161 caaatatcga agcagctgtt aatctaattc agggggctga aggtgtagtg acagggcttg
     8221 cgatggatac agagttttca acagcactgg cgaaagttac caatggggag atggggccta
     8281 aaatgtaccc tgaacttgct tggggagcgg atccagatag catcaatggc ttgaaatcgt
     8341 ccgtcaatac tactgttggt gctggagctg atgaagcaga atccaaagat ttagtaatta
     8401 ttggcgattt tgaaagcatg tttaagtggg gttatgcaaa acaaattcca atggaaatca
     8461 ttaaatacgg tgatcctgat aattcgggga aagaccttaa agggtataac caaatttact
     8521 tacgtgctga ggcgtatatc ggctggggta ttttggacgc taagagcttt gctcgtgtca
     8581 ctaaaggaga agtataatgt tatacgttaa cagtaagact ggagctagtt tttatagctc
     8641 cgtccctgtt tgtggtggag attggacttt ggttgaacag cagacaggcg aaaaagcaaa
     8701 aacagtagca gaaattaaac gtcagttaga tgctgctggg ataaaatata gctctaaagc
     8761 taagaaacct gaattagagg cactcttgcc tggttaggag gtaaaagtgg gcaattttgc
     8821 aacaacagat gacgtcattt tgttatggcg tcccttatct gttgacgaat tgaaacgtgc
     8881 aaatgcactc ttgaaagtcg tatcagatac attaagaatg gaagctgaca aagttggcaa
     8941 agacttagat aaaacaatgg ttgataagcc ttattttgtt aatgttatta aatcggttac
     9001 ggttgacatt gtagctagaa cactcatgac atctactcaa ggtgaaccga tgtcgcaaga
     9061 aagtcaatcg gcacttggct acacttggtc tggaacttat ttggttccag gagggggact
     9121 gtttataaaa gacaatgagc ttaaacggct tggtctaaaa aagcagaggt atggaggtat
     9181 tgagctttat ggggaaatta agagggataa cgattacttt gatagataaa gtaactatcg
     9241 atatagaccc tttcggaaat ccaataaaaa aagataaaga aatatctgtc gataatgtcc
     9301 ttgtatcgcc agcaacaagc gatgacataa caagccagct tagcctttca ggaaaaaaag
     9361 ctgtttacac tttagctatt ccaaaaggag acaaccacga ttggggagat aaggaagtta
     9421 gatttttcgg caaaaaatgg cgcacagtag gaattccact agaaggtatt gaagagctta
     9481 taccactaga ctggaataag aaagttatgg tggaaagata tgagtaagtt taaattcaag
     9541 cttaatagag ctggtgttgc cgaattgatg aaatcatcag aaatgcagca ggtattaacc
     9601 actaaggcca cagccatcag agaacgttgt ggtgatggtt atgtccaaga tatccatgtg
     9661 gggaaaaata gggccaatgc catggtcagt gctaaaacca taaaggccaa gaaagataac
     9721 tcaaaaaata acacactgtt aaaggcggtg cgctaattga ttgaagtaat tatcaaaaaa
     9781 tatttagacg agcacttaga tgtgccgtct ttttttgaac atcaaaaaga tgaacctaca
     9841 cgatttgtca ttttggaaaa aacaagcgga gctaagaaaa atcatatctt aagctccact
     9901 tttgcttttc agagttatgg caagtcaatg tatgaggctg ccttgcttaa tgagcaagtg
     9961 aagcaagttg ttgagcaatt agaaggattg cctgaaatag ctggtgtcca tctaaatgct
    10021 gactacaatt ttacagatac agaaacgaag cgttatcgct atcaaactgt atttgacatt
    10081 aatcactatt aacaaaagga gataataatg gcaaatgata ctaaaaatgt gacatctgca
    10141 aagccgaaag caggaggagc aatttacaca gcacctcttg gtacaaaatt gcctactgac
    10201 gccgttacag aattagataa agctttcaaa ggtcttggct atgtgtctga agatggcgtt
    10261 acaaacgaag atacacgatc ttcggaaaac atcaaagctt ggggtggaga tgttgttgga
    10321 gctgttcaga cggaaaaaga agataagttt acttataagc tgattgagtc actaaatgtg
    10381 gaggttctca aggaagttta tggttcttct aacgttactg gagatttaga taaaggtata
    10441 cacatcaagt caaactcaaa agagttagaa gctcatgcaa ttgttgttga catgattatg
    10501 aatggcggca tccttaaacg aattgtctta ccaaatgcaa aagttgatga agtaggtgaa
    10561 attgtctatg tcgatggcga agtcgttggt tatgaaacaa ccttaaaatg tttcccagat
    10621 gaaaatgggg acactcacca cgaatatatt gttaagccaa gggcacgaag tcttgaaatg
    10681 taaggggtat tgaatggaaa tcttaaaagg aaaaacaaca tcagggtttg aatacgaaat
    10741 ccctaaaaaa cgattaaaaa actttgaact tgtcgaagct attgcagaag aggaaactga
    10801 tccaacagca gtagttaaaa tcgttaattt gttacttggt gatgctgcta agtctctaaa
    10861 agaacatgta cgagatgcag atggtatcgt agatgttgaa gctatcggag tagaaatcaa
    10921 agaaattttt gaaagtcaaa aagatttaaa aaactagcaa tcctcgctca gatgatagta
    10981 aaagatgatg atgcgttaac ttgtgattta gctgaaacct acggcatata tgattacaaa
    11041 cagctacctg cttatcaggt ggctgttttt gctgtcggtt tgaggtctaa ctctaggata
    11101 aaaatggcat tatctggaga gactgaggct ttggatactg ttttgttagc tggtatttac
    11161 gataatacta atttgctgtt ttggtctaaa actaaggatg gtcaatctgg tcaaaacaaa
    11221 cctaaatcaa tggttgaagc tatatctgga tctaaatcac aaaaagctaa tgaagtcatt
    11281 tcttttgcgt ctggcgagga ttttgcaaat gcacgtaaac aattactagg aggtgatggc
    11341 taatggcaac agaacttggt caagcgtatg tgcaaattat gccatccgct cgtggaataa
    11401 gtggagcaat ctcgaagcaa cttgatcccg aagcaaggtc ggctggtttg agcgctggtt
    11461 cgctcattgg tggtaatctc gttaaaatga ttggtggtgc cattgcagct gctggaatcg
    11521 gtaagatgat ttcgtctgcc ttgtccgctg gtgctgattt gcagcaatct tttggtggta
    11581 ttgacacatt gtataagggc gctgagactg ctgtcaaagg gtttgctaaa gaggcataca
    11641 aagctggaat atcagcaaat acttatgcag agcaagcagt ttcaatgggt gcatctctaa
    11701 agcaatcact tggaggtgat gctgtcgcgg ctgccaaggc tgctaacatg gcaatcatgg
    11761 atatggccga caactcggct aagatgggta ctgatatcac atcaatccaa atggcttacc
    11821 agggatttgc taagcaaaac tatacaatgc ttgataacct aagacttggg tacggcggca
    11881 caaaagaaga gatgaagcgt cttttatcag acgctgaaaa gttacctgcc gctatgggca
    11941 agaagtttga tttgagtaat tatgctgatg tggttgaggc tatacacttg gtacaggata
    12001 acatgggtat cgctggagtt gctgctgaag aagcaaaaac tacattttca ggctcactag
    12061 ctgctatgaa gtcctctttt acaaatgtac tggcaggttt atcactagga gatgatataa
    12121 gacctgcttt acgaagactg gctgaaacaa cttctaattt cttatttggt aactttattc
    12181 cgatggtggc aaatatcttt aaaggattac catcggcaat tggtactttt attggagcag
    12241 caactcctat tattgccagt caatttaaag ggctaatgag tagccttggg attagtattg
    12301 atttaagtcc tattactgct aaatttgcgc agattggtca aaacttacaa cctgtttttg
    12361 atggtttaaa aaccgctttt gggcagttgc catcattttt tactagcatc ggtgatgcag
    12421 ttgcaccagt gatagacact attatcagcg gattagctag attagacttt agtggttttg
    12481 aggctttgat ttcagcaatc ttaccagcaa ttcaaacagg gttccaaacg ttcatgtcta
    12541 ttgtaggtcc agcgattagt cagcttgtaa atagttttgt taatctttgg aatgcttgcc
    12601 aacctctagt aacaatatta agtagcgcat tgatgccagc ttttcaaatt ttaggagctt
    12661 ttctcggcgg agtcttacaa ggaatccttg gcagtattag ctttgcattt gatgctttaa
    12721 aagttgttat tgagttttta acgccaatta ttgattggct tgtacaaggc tttaatgcta
    12781 tttcaccggc attacaaacc gttgcccagt gggttggtaa tgtcattggt atatttacta
    12841 gcttaggtgc atctgggcaa ggtttaagta gtatgctaag cagtgcttgg gggaacatcc
    12901 aaacagtagt ttcgacagct aaaaatatga taactttggc gattgatggt attaaattgg
    12961 tatttagcaa tctagggaat gctggaaata ttttaaaagg attactttcg gcagcgtggt
    13021 cagctatgca aaatgcagta gtgatagcta aaggtattat caacagtgcg ataagcgcta
    13081 taaaaacagc atttagcagc tttggtaatc ttgtatctag cgtaagtgga actataaaat
    13141 ctgttattgg cagtttaaaa aatgcgtttt acagtttagc aagtattgac ttagttggtg
    13201 caggacgtgc aatcatgcaa ggatttctaa atggactaaa atcgatgtgg ggggcaatca
    13261 ccggctttgt tgggggtatt gctgactgga tccgtaagca caaagggcct atctcatacg
    13321 atagggtttt gctaaaaccc gcaggtaaag taatcatgca agggttcaac aatagcttga
    13381 tggatggctt taaagaggtt aaatcaaatg tatctggcat ggctgacgat cttgcaggca
    13441 ccatgacagg taaaagtcta tctctcggta ttgatgctaa accaagtgtt actgctgatg
    13501 atttattatc aagcaatatt agtgctaaga ccacactaga ttctggcaca aacgacttgt
    13561 cattattttt tgttagagtg cttgctctat tgcaagacat tcttgacaag gatacagatg
    13621 tttatttgga taaagaaaaa gtcagcgcta ttttatacga agaatttgcc aaaatcatgg
    13681 ctagagaggg gattgcatga taccaaaggt tattattgat ggttttgata cctctacaat
    13741 ccctaattgt gtcctaactg gttatgatgt aggggatgtt ttatcccctc gctttgtcga
    13801 aaatgaagtg tatgggatga atggtactag caggggatta gagtcataca atgagtcgaa
    13861 acccactcta acatggcatt tgagcacttt tgatgatgca gttaatttag tgaatcattt
    13921 agacggactt gggaaaacca ttgaattttg gcatattccg aagtcatttt attattatga
    13981 ttgcctatct gtcaaaatca atgcggtaac tatgaagtcg tggagagtca cacttaaact
    14041 tgcactatat ccatttaggt atgcgaaagg tatctcagat gtaacgattg caggcaatgg
    14101 aagtataaat aatccaggaa atgttttcag tgaacccaag atagttgttg agggtactgg
    14161 aaaaggaacg ctaacaatcg gcaaacaagt tatggaatta aatttgtcag gtaaagcaac
    14221 gatcgaatgc aaacatggtc aacaatgtgt ttatgatact ggaggcaatg tgaaaaactc
    14281 aatccgaata agaggcagtt tttttgagat acaacccggt acgcaaggta tcgctgttag
    14341 cggtggcatt actaggttaa caatcagtcc aagatggagg tacaaagttt gatatcaatt
    14401 aaagatgata atacccctct tgtggctgcc tttgaggacg aaatcagcca ggaagctaat
    14461 agtgattaca aactaagttt taagtatccc gctaaacacg attaccgtcc tttgatcaaa
    14521 aaaggaataa tcctagaagc tgatgatcta catggaactc agctctttag ggtttttgaa
    14581 attactaagc gtcatggcta cattaatgtt tatgctaatc agattgccga tgacttaaat
    14641 ggctatgcaa ttaactctat tagtgttgat agagtacagg gcatgaaagt tatgtccgag
    14701 cttgcaggca gcatcaagcg agatcaccca tttagctttt ttagtgatat tgatggccgg
    14761 catacattta atcaatcaga tgtatctgtt atggatgctc tggccaatgg caagcactca
    14821 gttatgggtc aatggggtgg cgaacttgta cgtgataagt accaggttaa tttactcaaa
    14881 aaagctggca aagataccga agctcttttt atgtacaaga aaaacctcaa atcttatgag
    14941 gaaacggata ctatcaaagg acttatctca atactgcacc ttgttgcaga agtagaagaa
    15001 gagcatgaag gagaagccag agaagcttca gatggaaaca ttggtcatag tgaatcaccg
    15061 aaaaagaaaa cgattagggc gactgttgag agtaagctca aagacactca tccgataatt
    15121 gtcgaaaagt ctatcaaggt gcaggatcaa gatgtcaaaa cagaagagga cttgcttgca
    15181 tatggtaaga aatactttga aagtacactc tgcgatatac caggcaatag tttaaaaatt
    15241 gatgttacta ataactacga gggcaatgtt aggctatttg atacagcaat tgttttccac
    15301 gaactctatg atagagactt acggatgcaa attaccggat acaagttcgc ccctatggct
    15361 aatcggttga aatctattag ttttggagag attaaaacta atttagcaaa gcaaattagc
    15421 agtcaaattg ataataaggt ggctgaagca actgctcaac atgatgcagc atttgaagct
    15481 aaattacaaa agcaaatcga aaacgctgat cgtgtctttg atactaaaga agctaaactc
    15541 cgtaaagaaa ttgaagatgg tatcaaaaaa gctgaagcta atgctgaggt caaagttgct
    15601 gaggttaatg ctaaagtgct ggaagccgag aagatagcca aggaagttga tgagcggctc
    15661 aaaaaatttt tagctagtgc tgatgctaaa gagcaagatt ttgataaaaa acttgaagaa
    15721 tttagaaagt cactcaaaga cctcgaagtg gacgaaaagc agattgatga cgctttggct
    15781 aaagctgggt ttagcaagga cagcttagct gacattaaag ctaaactgga agacacgtct
    15841 gaaactgcca cagttacagc taacattgtt ggatcaactg gcggtacttt ttacaaccgc
    15901 aaccgactag aaggtgatac tgacaaagtt atcacttttg aacagggcta tattgacatt
    15961 gctcataacg gtgaaggttt tgaagaaggt aagacttata ctatcagctt tgaagctaca
    16021 tgtgagctac tcaaaaaagt ggctgtcacg ctgacacagg ctaataataa gggagttaaa
    16081 ctggtactga cacctactaa ggcaaaaatg gagcctgaga cttttactct aactaaggac
    16141 acagaggtta tcagcgttta tcctttgagc tatacggctg ttttaactgg cgattggtat
    16201 aaatctaagc aaatagattt aaatgcgttg gaggggtggg aattagctct ggacatgagc
    16261 tataaagatg ttgtggatgg caataatgct gatttagttt tggactgggc ggaaaaccca
    16321 gatattattt ttgatggaaa tggaggtatt taatgtcagg agaagttata tctgctagag
    16381 tcaggcataa aggcatgaca aaaagcgagt gggaatctag tgatgtaatc ttactggaga
    16441 gcgagatagg ctttgagaca gacacaggtt ttgccagagc aggtgatggc cacaatcgat
    16501 ttagtgacct tggatacatt agtccactcg attacaatct actgactaac aagccaaata
    16561 tcgatggatt agcgacaaaa gtcgagaccg ctcagaaact acaacaaaaa gcagataaag
    16621 agaccgtcta tacaaaagct gaatcgaagc aagagcttga caagaaatta aatctcaaag
    16681 gtggcgttat gacaggtcaa ctaaaattta agccagccgc cactgttgct tattcctcgt
    16741 caacgggtgg agcggtcaat attgacttgt cgtctagcag aggtgctggt gttgttgtct
    16801 attctaacaa tgatgcaagt gatgggccgt taatgagctt gcggacgggt aaagagacct
    16861 tcaaccaatc ggcgcttttt gtcgactaca agggaacaac aaatgccgtt aatattgcga
    16921 tgcgtcagcc aaccaccccc aatttttcat cggcgcttaa tattactagc ggcaatgaaa
    16981 atggtagtgc gatgcaaatt agaggcattg aaagagcatt gggaacgctc aaaatcacac
    17041 atgaaaaccc aagcgctaac gcaaaatacg atgaaaacgc tgcagcgtta tctattgata
    17101 tcgttggaaa acggggagcc agtggaaatg gtactgctgc ccaaggcatt ttcatcaatt
    17161 cgtccgcagg cacaactggt aaaatgctca gaatcagaaa taaaaatgta gacaaatttt
    17221 atgtaggtcc agatggtggc ttttggtcat gtgcaaattc aactgtagct ggtaatctaa
    17281 cagttaacga tccaacatct agcaaacatg ctgtgactaa agattacgta gataaagaaa
    17341 ttgctaagtt aaaagaactc atacaaaaaa aatagattaa ggaggataaa tgagcagaga
    17401 tccaacttat acaatcaacg agcacgactt atcttttaaa gatggtcgtt tttatgtgac
    17461 ttttagagca gataagtcta gcgagactgt cagacttaat agtagctgtc ttggcaatac
    17521 tgtcatcaaa aagctacagg tcgaggatga caatacaatg cacgactttg taaagcctaa
    17581 agttaccact caacaagctt ttggactagc tcagcaggtc aaagagcttg atttacagct
    17641 aaaagaccca aactctgatc tatggggtag aatcaagctt aataataagg caatgctagt
    17701 cgaatatggc aataaagaga tggccagtgc cattgcacag tcggctgagc agatattgtt
    17761 acaagtcaag tctattgatg atgaacgata ttccaaattt gagcaaactc tgaatggtat
    17821 caaacaaact gtcaaaagtg aatcggttga atctgcacgt actcagctag catcaatgtt
    17881 tgatagtcgt attagtggac ttgatggcaa atacagtcgt ttaagccaaa caattgatag
    17941 tcttagcagt cgtcttgatg atggtattgg taactactca acgctatctc aaaaggtaag
    18001 tggcattgat ttacgagtta gtaatgcagc taaagatgtc tctcgattgt ctcagacagc
    18061 acaaggattg cagttacaaa tcacaaatgc caatcaaaat tacagcagct tgtctcagac
    18121 tgtagggggt ctacaaacaa ctgtacatga taatcaatca aatgctacaa gtcggattaa
    18181 tcaattaagt gacttaatca gcactaaagt gactaagggt gatgttgaga caactattgc
    18241 tcaaagttac gacaagatag ctttggcgat taaggacaag ttgcctaaga gcaagatgac
    18301 tggtaatgag ataatctcag cgattaacct tgataggtct ggtgttaaaa tcactggtaa
    18361 aaacatcact cttgacggta atagctacat cagcaatgcc gtgatcaaaa atgctcatat
    18421 tgctaacatg gacgccggta agattaacac agggtacttg agtgctaata ggattgcggc
    18481 cgaggctatc actggtgaca aaatcaagat ggactatgcc ttttttaata agctaactgc
    18541 caatgaggga tattttagga ccttatttgc taaaaatatc tttaccacat ctgtacaggc
    18601 tgtcactacg tctgcgagta agattacagg tggtgtgctt tctgccacga atggtgcgag
    18661 taggtgggat ttgaatagtg caaatattga ttttaatcga gatgccacaa ttaattttaa
    18721 tagcaaaaac aatgccttag tacgtaaaga tggcacacat actgcctttg tacattttag
    18781 taatgcgacg cccaaaggtt atacagggtc agcgttgtat gcatcgatcg ggataacctc
    18841 atctggtgac ggtgttaact cggcttcttc cggtcgtttt gcagggctaa ggtcatttag
    18901 gtacgctacg ggatataatc acactgcggc agtcgaccag actgaaattt acggtgataa
    18961 tgttttagtt gtggatgatt ttaatattac tcggggattt aagtttagac cagacaagat
    19021 gcaaaaaatg cttgacatga acgacttgta tgcggctgta gtagccttag gccgctgttg
    19081 ggggcacttg gctaacgtcg gctggaatac tgctcatagc aattttacaa gtgctgtgaa
    19141 tagggaattg aataactaca tcacaaaaat ttaacaggag ataatatgca attaactatt
    19201 aaaaacaaag atttaaacac actatatcgt gtactagaca aaatcaaaat cacgaacatg
    19261 cgagcaaacc gcggacgtgc taagctactt gcaaaagtcg agggcaagct aagcgagtat
    19321 gccaaagatg aggttgatat tattgaccag tatgttgcaa aaaatgacga tggcaagtgg
    19381 attacagatg acaaaggtaa ttcaaaaatt gaggacacct caaagttagc tgagcttaac
    19441 gactttttag acgagttagc aagcgagcct atcgtcatca aaggtggcga gtactctaag
    19501 cgctttatcg attttttgga atatctagcc gaatctgaag atgagtttac agctcaagaa
    19561 atcattattg ttgacagcat cttagagcaa tacgaaggaa gcaaaggaga ataactatga
    19621 agacattaac actatcaggc aaaccttatc caattcatga aggcggtaaa gttgtaaaaa
    19681 cagagattcg tttaatcggt gacaatgggc tatttatccc cattgaatta atcggtgatc
    19741 agacagctaa gggagcagat gaccttatta aagagggact agatgctttt gtacgcgagt
    19801 atgtgactaa atacgccgtg gcggaatcag tgcaaaaagt ggaagagttg agcctcgcac
    19861 aaaaagagat tgagcaaaat gcggagcaag caaaggtaac agcagaagcc gctgaaaaac
    19921 aagctaaatc tctggagctt gtcattgcaa aatctcaaaa aatggctaat ctacaagcaa
    19981 tccatctact aacaagcgga agcaaagtgg aacccgatat ttacaaaggt cttttagagc
    20041 taatcgagcc agccaaaaaa ggtgagtatc aagcctatga tgtctttacg gtagtagacg
    20101 agtcgcacga agagcaggca ggagaaggta atcttgtctt tgtacacgtt aacgagccat
    20161 ttacttatga caaacagacg cttaaagagc tagaggaaga ggataaagtc acagtcatta
    20221 agtatgcgga cttagttaag taggattagc gaggtaagct atggcaacag agttgatatt
    20281 tggcctcggc ggctttattt tagctatagt aacgacttac aatattttta atgcaaaatc
    20341 catcaagcat gcgacagata ttactttgtt gcagtctgag gtagagcatt taaaaattgt
    20401 cactcggcaa aatgctaggc gtcttgagga gcatgatgag caaaacaaaa cgctcatcac
    20461 aatgacagag caaattaaaa atttaacaga tgatgttaaa gatttaaaag atatgatgag
    20521 aggagaaatc aaatgatcaa tttaaaatta cgactacaaa acaaagtaac cttgatggct
    20581 attttgggag ctatcttttt gttagcgcaa caattaggta ttaaattacc atcaaacatc
    20641 gcggatattg caaacacagc tgtaacgctt ttggtattgc ttggcgttgt cacagatcct
    20701 actacaaaag gcttatctga cagcgaacaa gcattgactt accatgagcc caaaaaatag
    20761 gaggagccat gcgagcaatc acacgattag cattagttat agcaatcgca atactgtatg
    20821 tgccattatc tgtggttg
//
LOCUS       DATTYN010000038        13025 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.38, whole genome shotgun sequence.
ACCESSION   DATTYN010000038 DATTYN010000000
VERSION     DATTYN010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13025
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.38"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(<1..947)
                     /locus_tag="VB649_001638"
     CDS             complement(<1..947)
                     /locus_tag="VB649_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670573.1"
                     /translation="MLTSKHHNLNKLVWRYGLTSAAAVLLAFGGGASSVKAEAPAAPL
                     TSEQRQKEIDKIKREIQAKYPKASEEKYWESSFWGRKYFNEQEYLKSLQTFTEQRLQD
                     IVNLIEKGATKGDKGEAGPAGPAGPRGERGPAGEAGKQGERGEQGIQGPKGETGAVGA
                     QGPKGDKGDTGERGEKGDTGATGAQGPQGEAGKDGAPGEKGEKGDRGETGAQGPVGPQ
                     GEKGETGAQGPAGPQGEAGKPGEQGPAGPQGEAGKPGEKAPEKSPEVTPTPETPEQPG
                     EKAPEKSPEVTPTPETPEQPGEKAPEKSPEVTPTPEMPE"
     gene            1328..1810
                     /gene="nrdI"
                     /locus_tag="VB649_001639"
     CDS             1328..1810
                     /gene="nrdI"
                     /locus_tag="VB649_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEP1670574.1"
                     /translation="MPQITLVFISLSGNTLSFVKRLSLYLADKYDYHVKQINIKDLKH
                     ETFPVKEEFVAILPTYLEGGNGVDSGEVEILTTPLGEFIAAHGNAQRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
                     "
     gene            complement(2203..3021)
                     /locus_tag="VB649_001640"
     CDS             complement(2203..3021)
                     /locus_tag="VB649_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEP1670575.1"
                     /translation="MTKVLTLNTHSWMQANTLKKLVALAEHILAEKYDIMCLQEINQL
                     IESELATDLPRYQALSGTPSIHKDHFALLLIHYLQKRGQHYYWSWAYNHIGYDIYQEG
                     VAILSKQPIYVSDILVSAMDDETDYHTRRSLIAKTRLDGKEVAVVNVHLSWFDKGFLG
                     EWEKLEKELLTLNCPLLLMGDFNNPTDQDGYQVMMGSPLNLQDSHKVADHVFGDHSIV
                     ADIDGWQGNKEALKVDHVFTSKDFIIRSSKITFEGGDAPVVSDHYGLEVTLGWR"
     gene            complement(3104..5290)
                     /locus_tag="VB649_001641"
     CDS             complement(3104..5290)
                     /locus_tag="VB649_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEP1670576.1"
                     /translation="MKTSFKQLFSFEFWQKFGKCLMVVIAVMPAAGLMISIGNSIPMI
                     NHDSAFLASLGNIIAQIGWAIIVNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAFYGVSGAMLADPEAKITSLLGTQMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPEVLTFFNGKRFVPFVVILRSILVALVLVVVWPVIQSGINGFGMWIA
                     SSQDSAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVHLKGSDASAYSHLMDSVTPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHTYKMMFISAAAAVFLTGVTEPLEYLFMFAAMPLYIVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMALKAGLGMDVINFVWVSILFAVIMYFIADMMIKKMHLATAGR
                     LGNYDADILGDHNTQATPTQVADSNSQVVQIINLLGGAGNIDDVDACMTRLRVTVKDP
                     AKIGAEDDWKKAGAMGLIQKGNGVQAVYGPKADILKSDIQDLLDSGALIPEVNMAKVA
                     DKPMPAKDFRHVTEKVLSVADGMVLPITGVKDQVFAAKMMGDGFAVEPTNGNIYAPVA
                     GLVTSVFPTKHAFGLLTNNGLEVLVHVGLDTVALNGVPFSVKVSEGQRVHAGDLLVVA
                     DLAAIKSAERETTIVVAFTNTTEIQDVTLTSLGNQPAKTKVATVEL"
     gene            complement(5647..6396)
                     /locus_tag="VB649_001642"
     CDS             complement(5647..6396)
                     /locus_tag="VB649_001642"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEP1670577.1"
                     /translation="MQQYFIKGKAEKEVTITDKDTIKHMFQVMRLADEAEVILVFDDG
                     VKYLAKVTNSMAHELEIIEALPDHVELPVKVTIASGFPKGDKLDTIAQKVTELGASAL
                     WGYPADWSVVKWDGKKLAKKEDKLAKIVLGAAEQSKRNRVPEVHLFEQKAEFLKSLSS
                     FDHIFIAYEETAKAGQLATLAREVKEVKPGAKLLFIFGPEGGISPVEITQFEAAGAIK
                     VGLGPRIMRAETAPLYALSALSYALELQASK"
     gene            complement(6396..7349)
                     /locus_tag="VB649_001643"
     CDS             complement(6396..7349)
                     /locus_tag="VB649_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEP1670578.1"
                     /translation="METWQEVTVHVHRDAQEAVSHVLIETGSQGVAIADSADYIGQKD
                     RFGELYPDVEQSDMIAITAYYPSSTNLADVIATINEQLAELASFGLQVGQVTVDSQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYDASTGEKVIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKTIYAYDLDDVAVRVAQENIDLNQ
                     GTDNIHVAAGDLLKGVSQEADVIVANILADILVLLTDDAYRLVKKEGYLILSGIISEK
                     LDMVLEAAFSAGFFLETHMVQGEWNALVFKKTDDISGVIGG"
     gene            complement(7420..7890)
                     /locus_tag="VB649_001644"
     CDS             complement(7420..7890)
                     /locus_tag="VB649_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEP1670579.1"
                     /translation="MAKYGFLSVLEEEMDKHFQYDYAMDWDKKNHAVEVTFVLEAQNK
                     EAIKTIDDSGEMTQDDIVFEDYVLFYNPAKSQFDAADYLVTIPFDAKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKVDFFLEWNAQAFEEGQQGLEEAASYPYPRY"
     gene            8090..9847
                     /gene="pabB"
                     /locus_tag="VB649_001645"
     CDS             8090..9847
                     /gene="pabB"
                     /locus_tag="VB649_001645"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEP1670580.1"
                     /translation="MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQ
                     QLGYYVVGYLSYETAAFFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIP
                     NQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTIQLTQELNAADSLAIYNKLVVEQA
                     AGYNAYITHDEFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNTWLDQQEHDWLQAD
                     GKNRSENMMIVDLLRNDMGKICQTGSVRVDKLCEVERYSTVWQMTSTIVGDLKADCDL
                     MDILKALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTI
                     QLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFL
                     EQHLNRLKEAATYFAYPYNEKALQKQLSTYLENKDNAAYRLMIRLSKDGKISLSDQPL
                     EPLSADFLTAQLSLQKKDVTASPFTYFKTSYRPHIEQKSYEQLFYNQAGQLLETSIGN
                     LFVQLGQTLYTPTVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGGNAVRGL
                     YPLNLELTHLDALLAKSQA"
     gene            9880..10446
                     /locus_tag="VB649_001646"
     CDS             9880..10446
                     /locus_tag="VB649_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEP1670581.1"
                     /translation="MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANA
                     LVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQ
                     STIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
                     FGLQFHPESIGTPDGMTMIANFIAAIPR"
     gene            10479..11747
                     /locus_tag="VB649_001647"
     CDS             10479..11747
                     /locus_tag="VB649_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEP1670582.1"
                     /translation="MPDHLALRMRPKTISEVIGQKHLVGEGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTRYAFRTFNATIDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLENDTIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKTAIQ
                     LAISDKERGFPFLVTIDDEALDFIVTATNGDLRSAYNSLDLAVMSTSPNEDGSRHISL
                     ETMENSLQRSYITMDKNGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLAR
                     RLTIIAYEDIGLANPDAQVHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYL
                     AMDAALADLRTSGNLPIPRHLRDGHYAGSKDLGNAKDYLYPHAYPEKWVKQQYLPDKL
                     VGHHYFEANETGKYERALGSNKERIDKLSD"
     gene            11836..12032
                     /gene="ssrS"
                     /locus_tag="VB649_001648"
     ncRNA           11836..12032
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="VB649_001648"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            12033..12105
                     /locus_tag="VB649_001649"
     tRNA            12033..12105
                     /locus_tag="VB649_001649"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12066..12068,aa:Lys,seq:ctt)
     gene            12320..13021
                     /gene="smeZ"
                     /locus_tag="VB649_001650"
     CDS             12320..13021
                     /gene="smeZ"
                     /locus_tag="VB649_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal mitogenic exotoxin SmeZ"
                     /protein_id="HEP1670583.1"
                     /translation="MKKTKLIFSFTSIFIAIISRPVFGLEVDNNSLLRNIYSTIVYEY
                     SDTVIDFKTSHNLVTKKLDVRDARDFFINSEMDEYAANDFKAGDKIAVFSVPFDWNYL
                     SEGKVTAYTYGGITPYQKTSIPKNIPVNLWINGKQISVPYNEISTNKTTVTAQEIDLK
                     VRKFLISQHQLYSSGSSYKSGKLVFHTNDNSDKYSLDLFYVGYRDKESIFKVYKDNKS
                     FNIDKIGHLDIEIDS"
BASE COUNT         3647 a         3025 c         2533 g         3820 t
ORIGIN      
        1 tgctctggca tttctggcgt tggtgtcact tctgggctct tttctggagc tttttcgcct
       61 ggttgctctg gcgtttctgg tgttggtgtc acttctgggc tcttttctgg agctttttca
      121 cctggttgct ctggtgtttc tggcgttggt gtcacttctg ggctcttttc tggagctttt
      181 tcacctggtt tgcctgcttc accttgtggg cctgctggac cttgctcacc tggtttgcct
      241 gcttcacctt gtgggcctgc tgggccttgt gcgccagttt cacctttttc accttgtggg
      301 cctactggac cttgagctcc ggtttcaccg cggtcacctt tttcaccctt ttcgcctgga
      361 gctccatctt taccagcttc accttgtggg ccttgtgcgc cagttgctcc ggtgtcacct
      421 ttttcaccgc gctcgccggt atcacctttg tcgcctttag gtccttgggc accaactgcg
      481 ccggtttcac ctttaggacc ttgaattcct tgctcaccgc gttcaccctg tttaccagcc
      541 tcaccagctg gtccgcgttc gcctcgaggt ccggctgggc cagcaggacc agcttcaccc
      601 ttatcgcctt ttgttgcacc tttttcaatc agatttacaa tatcttggag tctttgctca
      661 gtaaaagttt gtaaagattt tagatactct tgttcattaa agtactttct tccccaaaag
      721 ctactctccc aatatttttc ctcagacgct tttggatatt tagcctgaat ttcccgttta
      781 atcttgtcga tttctttttg tctctgctcc gatgtcagag gagcagctgg agcctcagcc
      841 ttaacgctgc ttgccccgcc tccaaaggct agaaggacgg cagcggctga ggttagcccg
      901 tagcgccaga ccagtttgtt gagattatgg tgttttgatg tcaacatatg ttgttctctc
      961 tttctttatt agatggtgtg ttttagataa aataacatgg tagctggacc tgattattta
     1021 taatagtatt ataatagagt gtgaaaacga ttgtaaagtt ctcttttgtt gttcatcttt
     1081 tagattttga ctgatcactc ttttgtggag atcagagggc tactttggca cttgcctgcc
     1141 tcgtttttaa gtcgagggca tccggatctt ttctttaagg tcactctttt ttgaaatgtt
     1201 actttttttg actgcttata ccttcttgtc tggttggata ccgctaggtt tcttctttac
     1261 ttgtttgttg gttttgattg tggtaagctt atgaggacac cttataggat taaaaaagga
     1321 gacacctatg cctcagatta cccttgtttt tattagcctc agtggcaaca cccttagctt
     1381 tgtcaagcgt ttatcccttt atctagcaga caagtatgat taccatgtca aacagattaa
     1441 cattaaagat ttgaagcacg agacttttcc cgtcaaagaa gagtttgtgg cgattctacc
     1501 cacttatcta gaaggcggaa atggcgttga ctctggtgag gtggagatcc tcaccactcc
     1561 tttgggagaa tttattgctg cccatggcaa cgcccagcgt tgtcttggga ttattggctc
     1621 aggcaacaaa aactttaacc atcagtattg cctgacagcc aaacaatacg ccaaacgctt
     1681 tggctttcca ctgctaggtg attttgagct gcgagggact cctgatgaca tttcgcggtt
     1741 agcccaggtc atcatggagg ccagctccag acactcgtct aacgacacac agacattgcc
     1801 taacagctag accgtctata gatgatcata gctgttttaa aaagagcgct tttaggacac
     1861 caactacaga ggtctcctac cccacgcctt gtgatttctc agcctttgaa aagagcgatc
     1921 acagtgcttc ttggggcttg ggatcacacc aagcactcct agaaataccc ctatgcagac
     1981 tttagcaagg caactatacg cttggtggta ctttctgtga agctcagatg gttggtgaca
     2041 aaaaagccct ggttttctaa ggtcactgat atgactaaag aggtctaacc agctctacct
     2101 tgagctcgtt agacctcttt gtgttctcct aatcccccta gacgatcgca gtttcttatg
     2161 tgtcttggct tctcctatgt ggtgtgcctg ttagcacatg ctctaacgcc agcctaatgt
     2221 cacttctaaa ccgtagtggt cactgacgac tggcgcatct ccgccttcaa aggtaatctt
     2281 agaagaccgg atgatgaagt ccttgctggt aaagacatgg tctaccttga gggcttcttt
     2341 gttaccttgc cagccatcaa tatcagccac gatgctatga tcaccaaaca catggtcagc
     2401 aaccttatgg ctatcttgta ggtttagggg gctacccatc atcacttgat aaccgtcttg
     2461 atccgttgga ttgttaaaat ctcccataag tagcaaggga cagtttagtg tgagcagttc
     2521 tttttctaat ttctcccact cccctaaaaa ccccttgtca aaccaagata ggtgcacatt
     2581 gacaacagcg acttctttgc catctaacct ggttttggct atgagtgagc gtctggtgtg
     2641 gtagtctgtt tcatcatcca tcgctgacac gagaatatct gaaacataaa taggttgttt
     2701 tgataagatt gccacgcctt cctggtaaat gtcatagcca atatggttat aagcccaaga
     2761 ccaataatag tgctgccctc gtttttgtaa ataatggatc aagagaagag caaaatggtc
     2821 tttatgaatg cttggtgtcc ctgaaagagc ttgatatctt ggtaaatctg tggccagctc
     2881 gctctcgatt aactgattga tttcttgcaa gcacatgata tcgtattttt cagctaaaat
     2941 atgctcagcc aaagcaacta attttttaag agtgttggct tgcatccacg aatgggtatt
     3001 cagtgttaat accttggtca ttaatcctcc tttataagac aagaatagcc atagggccta
     3061 aaccagctat ggctattacc tatcactatc tcgtgatgtt ttgttaaagt tctacggtgg
     3121 ctactttagt cttagcaggt tgattgccta aagaagtcaa ggtcacatct tggatctctg
     3181 ttgtgttggt aaaagcaaca acaatggttg tttcacgctc tgctgattta atagcagcaa
     3241 ggtctgctac gactaatagg tcacctgcat gaacccgttg cccttctgag actttgactg
     3301 aaaaaggcac accatttaag gcgacggtat caagtcccac gtgcaccagc acttcaagac
     3361 cattatttgt cagtaaacca aaggcatgct tggtcggaaa gacactggtc acaaggccag
     3421 ctacgggtgc atagatattg ccatttgttg gttcaaccgc aaacccatct cccatcatct
     3481 tagccgcaaa cacctggtct ttcacacctg tgattgggag aaccatcccg tctgccactg
     3541 atagcacttt ttctgtcacg tgtctaaaat ctttggctgg cattggtttg tcggctactt
     3601 ttgccatatt gacttctgga ataagagcac ctgagtccag caaatcttga atatctgatt
     3661 tcaaaatatc tgctttaggc ccatagaccg cttgaacgcc gttgcctttt tggatcaagc
     3721 ccatagcgcc agcttttttc caatcgtcct cagcgccaat cttagcgggg tctttgaccg
     3781 tcactcgtaa gcgcgtcata caagcatcaa catcatcaat attgcctgcc ccaccaagga
     3841 gattaatgat ttgtacgact tgagagttgc tatctgctac ttgggtcggt gttgcttgag
     3901 tattatggtc acccagtata tcagcatcgt agttgcctaa acggccagct gttgcgagat
     3961 gcattttctt gatcatcata tccgcaataa agtacatgat aactgcaaag aggatagaaa
     4021 cccaaacaaa gttaatcaca tccatgccta ggcctgcttt aagagccata ggggtacggg
     4081 tcaataattc aatgttccca aatgagtgaa cacggagatt cacaaggtca gccatggcaa
     4141 atgaagctcc ttgaacaagg gcatagacga tgtaaagtgg cattgctgca aacataaata
     4201 ggtactcaag tggctcagtt acccctgtca aaaagaccgc tgccgctgct gagatgaaca
     4261 tcattttgta tgtgtgtttt ttatcggcat ccacattacg gtacatggct aaggcaaccc
     4321 ccatcaatgt tccggtagct ccaatcattt gtcctacctt aaagcgagct ggagtcacac
     4381 tatccattaa gtgactatag gctgaagcgt ctgatccttt aaggtgaaca aggtcagtta
     4441 cccaagcaag ccacaaaggg tcttgaccaa atacttttgt tcccgctgct gcacctgtca
     4501 tgacctcata agttccacca agagctgtat agttcattgg gatcgtcaac atgtggtgaa
     4561 gaccaaatgg caacaagaga cgttccaagg taccatatag gaatggggct aggattggag
     4621 ctgaatcttg tgaagaggca atccacatcc caaaaccatt gattccagat tggataaccg
     4681 gccaaacaac cactaagaca agcgctacta ggatagaacg caagatgacc acaaaaggta
     4741 caaaacgttt cccgttaaag aaagtcaaaa cttcaggaag tttacggtaa ttatagtatt
     4801 tgttataggc tgttgcccct acgaaccctg cgataatccc aacaaaaacc cctgtgttta
     4861 gggctggaga ttccaagaca ctggtgaaat aatctttaac aatcatttga gtgccaagga
     4921 ggcttgtgat ttttgcttct ggatcagcta gcatagcacc agacactcca taaaaagcac
     4981 ctgtaattcg attgatcaag acaaaagcaa gacctgaggc aaaggctcct cctgcacgtt
     5041 ctttagccca actaccacca atggccaagg caaatagcaa gtgaaggtta acaatgatag
     5101 cccaaccaat ctgagcaata atgtttccta gagatgccaa aaatgctgag tcatggttaa
     5161 tcattggaat ggagtttccg atactgatca ttaaaccagc cgctggcatg acagcaataa
     5221 cgaccataag acatttaccg aatttttgcc aaaactcgaa actaaacagt tgcttgaatg
     5281 atgttttcat tctatctctc ctttattatc cccttttagc catagctgcc cttaaggtgc
     5341 ttttgtgaca caatgatata gactacaact cagcgatgca atcgcttgca ttgatctgat
     5401 acctttatta tactagcctc gcagcaattt gtaaagcgtt ttcttagaca gatgttagtc
     5461 gtttttcttc attaaatggt agtgtaactt accaaaaaga tgacaagagc ccatttcctt
     5521 ttttggtgat gagcccatca acgctcttca aaaaaacaag aagcaataaa aaaaggccgt
     5581 tgacacaatc gtgaactgcc tgttcgtttc tttagcctct tctttctaaa gtaagcaaca
     5641 gcttacttat tttgatgcct gcaattccaa agcataacta agagcactta aggcatatag
     5701 cggcgctgtc tctgctcgca taatgcgagg acccaaaccc accttgatgg cacctgctgc
     5761 ctcaaactga gtgatttcaa ctggggaaat tcccccttct ggtccaaaga taaagaggag
     5821 ttttgcccct ggcttaactt cttttacttc acgcgccaag gtcgctagct gacctgcctt
     5881 agctgtttcc tcataagcaa tgaagatatg atcaaagcta gaaaggcttt ttagaaactc
     5941 tgctttctgt tcaaaaaggt gaacttcagg caccctattt cgtttgctct gctcagccgc
     6001 tcctaataca atcttagcca atttgtcttc ttttttagct aattttttgc catcccattt
     6061 gaccactgac cagtctgctg ggtagcccca aagcgcactg gctcccaatt cagtcacttt
     6121 ctgggcaatc gtatctaact tatctccttt aggaaatcca gaagcaatag tcaccttaac
     6181 aggcaattcc acgtgatctg gcaaagcctc tataatctct aactcatgag ccatactatt
     6241 ggtcaccttg gctaaatact tcaccccatc atcaaagacc aagataactt cagcctcatc
     6301 agccaagcgc atcacttgaa acatgtgctt gatggtatct ttatcggtaa ttgttacctc
     6361 tttttctgct ttgcctttaa taaaatactg ttgcattagc caccgatcac tcctgagata
     6421 tcatctgttt ttttaaagac aagggcgttc cactcgcctt gaaccatgtg agtttctaag
     6481 aaaaagcctg cgctaaaggc agcttccaga accatatcca atttctcaga aatgatgcca
     6541 gataagataa ggtaaccttc ctttttgacc aaacggtaag catcatcagt caataagacc
     6601 aaaatatctg ccaaaatatt agccacaatc acatccgctt cttggctaac cccttttaaa
     6661 aggtcgccag cagccacatg aatgttgtct gttccttgat tcaaatcaat gttttcttga
     6721 gccactcgaa cagccacatc atctaaatca taagcataga tggttttggc acctagtaag
     6781 gaactggcaa tcgagaggac acctgaaccg gtccctacat cgataactgt ctcaccacca
     6841 cgaaggactt gttccaaggc aaaaaggctc atcttagttg tgggatgtgt ccctgtccca
     6901 aatgccattc caggatctaa tttaatcact ttttccccag tagaagcgtc ataatccgtc
     6961 caactaggga caatggttaa atcatgcgtg atacgagctg gttcatagta ttttttccaa
     7021 ttgtctgccc agtcttcctc agccaattcc tgactatcca cagtaacctg accaacctgt
     7081 aacccaaaac tagctaactc cgctaactgt tcattaatgg tcgcaataac atccgccaaa
     7141 ttagtgctac ttgggtaata ggctgtgata gctatcatat cagactgctc cacatctggg
     7201 tataactccc caaagcggtc cttttgccca atatagtctg cgctatctgc gatagcaacc
     7261 ccttgactgc ctgtctcaat caacacatgt gaaacagcct cttgcgcatc acgatgcaca
     7321 tgaaccgtca cttcttgcca cgtttccata agtatgtcct ttctattttg accttttggt
     7381 tattgtccta atagtgttag caccatctcg tgtgtcacct tagtaccttg ggtaagggta
     7441 acttgctgct tcttctagtc cttgttgacc ttcttcaaaa gcttgcgcat tccactccaa
     7501 gaagaaatca accttgctgt catctgctaa gaaatccatc aaatcgctgt gcccttcaat
     7561 agcaacatcg ttgagaaatt gcgcaaagta agctaagaat tcacgagaaa agcccttttt
     7621 agcgtcaaaa ggaatagtaa ccaaataatc tgctgcatca aattgagact tggcagggtt
     7681 gtaaaagagc acatagtcct caaagacaat atcatcttgg gtcatttcgc cactgtcgtc
     7741 aatggttttt atggcctctt tattttgagc ttctaacaca aaagtcactt caaccgcatg
     7801 atttttcttg tcccaatcca tagcatagtc atactgaaaa tgcttatcca tttcttcttc
     7861 taatactgat aaaaagccat attttgccat cttttttata cctaatcttt ctaactgttg
     7921 ctgtataagg ctttgtaaga cctcattagt ttacttactt tgacatgctg agcgtactgt
     7981 tataactttt attaactgaa ttataacata tttgactaat attgaccata agagaaggtc
     8041 ttaatggctg gatcacctct agcaaccgct tttatgatat aatttgggta tgcatagaaa
     8101 aacgattatt gatttcaaag agctcgggca acgctatctt tttgatgagc cattagtaga
     8161 attggtagcc aagtccttag atcaggtcgg tccagtcatt gaaaaagtac aacactacca
     8221 acagctgggc tattacgtgg tgggctatct cagttatgaa acagctgctt tttttgacaa
     8281 tgccttacaa acccataatg acagactagg caacgagtac cttgcctatt ttacagtgca
     8341 caaaacctgt caaaaaaaag acctacctct tgattatgac agcattacta tccctaacca
     8401 atgggtcagc gcaactcaaa aagaagccta tcaaaaagcc attgaaacca ttcaccgtga
     8461 gatgcaacag ggcaatactt atcaggttaa ctataccatt caattaactc aggaactcaa
     8521 tgcagctgac agcttagcca tttacaataa actcgtcgtt gaacaggctg ctggctacaa
     8581 tgcctatatc acccatgatg agtttgccgt tatttcagct agtcctgagt tgttctttaa
     8641 acaagagggc aacaggttaa ctactaggcc tatgaaaggc accactaagc gcggggttaa
     8701 cacctggctg gatcaacaag aacatgactg gctccaagct gacgggaaaa atcgctctga
     8761 aaacatgatg attgtggatt tgctccgtaa tgacatgggg aaaatttgcc aaacaggcag
     8821 tgttcgtgtt gataagctct gtgaggtcga gcgatactct accgtctggc aaatgacctc
     8881 aactattgtt ggtgacctca aagcggactg tgacctgatg gacattctca aagctctctt
     8941 tccttgtggc tctatcacag gggcaccaaa agtctccacc atggcaatta tcacatctct
     9001 ggagccaaaa ccaaggggga tttattgtgg aagtattggc atttgtttac ctgacggtcg
     9061 ccgtttcttc aatgttccca ttagaaccat ccagctcagt cataatcaag ctacttatgg
     9121 tgtcggaggc ggtatcactt ggcaaagcaa gtgggaagac gaatacgagg aagtccatca
     9181 aaaaacagct tttctctatc ggcacaaaca aatctttgac ctcaaaacaa ccgccaaggt
     9241 ggaacacaaa aaaatagcct tccttgagca acacctcaat cgccttaaag aagcagccac
     9301 ttattttgct tacccttaca atgaaaaagc tttgcagaaa caactgtcaa cctatttgga
     9361 aaataaggat aatgctgcct accgcttgat gattcgttta tccaaggatg gaaagattag
     9421 cctctctgat caacccttgg aacctttgtc agccgatttt ctgacagctc aactctcttt
     9481 acagaagaag gacgtgacag cttcgccttt tacctacttt aagaccagct accggcctca
     9541 tattgagcaa aaatcttatg aacagctatt ctataaccaa gcggggcaat tattggaaac
     9601 gtccattggc aatctctttg ttcagctggg tcagaccctc tacacaccaa cagtggctgt
     9661 ggggatttta ccaggacttt ttcgccaaga gctgctagct actggtcaag ctcaggaaaa
     9721 agaggtgaca ctagctgatt taaaagaggc tagcgctatt tttggaggaa atgctgtccg
     9781 tggcctctat cctctcaacc ttgagcttac tcaccttgat gccctcttag ctaagagtca
     9841 agcctaaact gccactcatc ttttgttatt aaggaaccta tgatactctt aattgataat
     9901 tacgattcat ttacctacaa cctcgcccaa tatttaagtg aatttgacga gacgattgtc
     9961 ttgtataacc aagacccaaa cttatatgac atggccaaaa aagctaacgc tctagtcctc
    10021 tcacctggtc ctggttggcc caaggaagcc aaccaaatgc caaaactcat tcaagacttt
    10081 taccaaacaa aacctatctt aggagtgtgt ctgggacacc aagctatcgc tgaaacttta
    10141 gggggaacct tacgcttggc caaacgcgtc atgcatggga gacaaagcac cattgaaacg
    10201 caaggccctg ctagtctttt tcgctccctg ccacaagaga tcaccgtcat gcgctaccat
    10261 tccatcgttg tggatcagtt accaaaaggt tttagcgtaa ccgctagaga ctgtgacgat
    10321 caagaaatca tggcatttga acaccacacc ctgccacttt ttgggctaca atttcaccca
    10381 gaaagcatcg gaactcctga tggcatgacc atgattgcta acttcatcgc agctattcca
    10441 cgttaatccc atcccccaaa agaaagaagg acagttacat gcccgatcat ttagcgctca
    10501 gaatgcgccc caaaaccatt tcagaggtca tcggacaaaa acaccttgtt ggcgaaggca
    10561 aaatcatccg tcgcatggtg gaagcaaata gactatcgtc tatgatcctc tatggaccac
    10621 caggaatcgg taaaacttcc attgcttctg ctattgctgg tactactaga tatgcctttc
    10681 ggacctttaa tgccaccatt gacagcaaaa aacgtctcca agaaattgcg gaagaagcta
    10741 aattttctgg tggcttggta ttattactag acgagattca tcgccttgac aagacaaaac
    10801 aagattttct tttaccttta cttgagaacg acaccattat catgattggc gcaaccactg
    10861 agaatccctt cttttcagtg acacccgcta tcagaagcag ggtccagatt tttgaattgg
    10921 aaccactttc taacgaggat attaaaacag ccattcagct agcaatttcc gacaaagaac
    10981 ggggatttcc ttttttagtg acaattgatg atgaggcgct agatttcatt gttaccgcca
    11041 caaatggaga cctacgatct gcttataatt ccttggatct agcagtcatg tctacttctc
    11101 ctaatgaaga tggtagccgt catattagtc tagagacaat ggaaaatagt ctgcagcgta
    11161 gttatattac catggataaa aacggggacg ggcattatga tgttttatct gccttacaaa
    11221 aatccattag aggttctgat gtcaatgcta gcctgcacta cgccgctcgt ttagtagaag
    11281 ctggagactt gcctagttta gcaagacgat tgaccattat tgcttacgaa gatattggct
    11341 tagccaaccc tgacgcccaa gttcataccg tcaccgcact agatgccgct caacgcattg
    11401 gttttccaga agctcgtatt cttatcgcta acgtggtcat tgatttggct ctatcaccta
    11461 aatccaattc agcttattta gctatggatg cagctttagc tgatttgaga acatcaggta
    11521 acctccccat tccaaggcat cttagagacg ggcattatgc tggcagcaag gacctaggca
    11581 atgccaaaga ttacctctac ccacacgcct accctgaaaa atgggtcaaa caacaatacc
    11641 taccagataa attagtagga catcattatt ttgaagccaa tgaaaccggt aaatacgaac
    11701 gcgcacttgg ttcaaataaa gagcgtattg ataagctctc agactgactg ctagttttaa
    11761 aaatcgcaac cgatttcaaa aatcgataat tttgcttgaa aaaattttaa aaagtggtat
    11821 tataaaagta cagaaacatt gctgtggcat acgaatccac atctaagtgt tgaccgacta
    11881 tttctttgta ttttcgggaa acaaagactc tttctagtct gcaagccgtt tcacgcggac
    11941 gcaacttcca agaaagagcg cgttacccac ctgcttatac tgcgcgggct caatacaaaa
    12001 acgtggatca ccggtgccaa tacagcattc ttgcctcctt agctcagttg gtagagcagt
    12061 agactcttaa tctatgggtc acaggttcga gccctgtagg gggtatcata ctatacataa
    12121 aaaagccttt atttaaaggc ttttttgctt gtttcataac taatcggctt aattaaaagc
    12181 gtcaatccac ttttagtatc atgtctcaat tttcatttga tagtcagcaa gtatatctac
    12241 aaaattgtta atgattattt cttttgaaag tgttatatta aaacataata aaataataac
    12301 tcctgaaaag aggctattta tgaaaaaaac aaaacttatt ttttctttta cttcaatatt
    12361 cattgcaata atttctcgtc ctgtgtttgg attagaagta gataataatt cccttctaag
    12421 gaatatctat agtacgattg tatatgaata ttcagataca gtaattgatt ttaaaaccag
    12481 tcataactta gtgactaaga aacttgatgt tagagatgct agagattttt ttattaactc
    12541 cgaaatggac gaatatgcag ccaatgattt taaagctgga gataaaatag ctgtgttctc
    12601 cgtcccattt gattggaact acttgtcaga aggaaaagtc acagcatata cgtacggcgg
    12661 aataacaccc taccaaaaaa cttcaatacc taaaaatatc cctgttaatt tatggattaa
    12721 tggaaagcag atctctgttc cttacaacga aatatcaact aacaaaacaa cagttacagc
    12781 tcaagaaatt gatctaaagg ttagaaaatt tttaatatca caacatcaat tatattcttc
    12841 tggttctagc tacaaaagtg gtaaattagt ttttcataca aatgataatt cagataaata
    12901 ttctctcgat cttttctatg taggatatag agataaagaa agtattttta aagtatacaa
    12961 agacaataaa tctttcaata tagataaaat tgggcattta gatatagaaa ttgactccta
    13021 attca
//
LOCUS       DATTYN010000039        12144 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.39, whole genome shotgun sequence.
ACCESSION   DATTYN010000039 DATTYN010000000
VERSION     DATTYN010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12144
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.39"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..264
                     /locus_tag="VB649_001651"
     CDS             <1..264
                     /locus_tag="VB649_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEP1670584.1"
                     /translation="SDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGIYKQGDTVSF
                     DSEGYANGYYWISYVGGLGMRDYLAIGQTDKDGNRISIWGKLN"
     gene            404..928
                     /locus_tag="VB649_001652"
     CDS             404..928
                     /locus_tag="VB649_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEP1670585.1"
                     /translation="MHALFVANYIIEYSNKKGYKINNLKLQKLLYFVNVRNILENGAP
                     LFEESMEKWKYGPVVPDVYHEYKRFGAFSISTDEMIMEYVEFSVSPFGELSDLEITEY
                     DSQKVENTQLIENTVDALHGFGPFELVDITHDHTPWKKYEDRIMDGVQGIKYTIEEIK
                     DFFGHNPGAKIWVQ"
     gene            916..1782
                     /locus_tag="VB649_001653"
     CDS             916..1782
                     /locus_tag="VB649_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HEP1670586.1"
                     /translation="MGTIAPAFMELLLDANFCKAPVNNQDTLLKVYHREMAKDNVTIP
                     YEIIAEYVYSHEDSVEENEKLNSNIDFIISEFSGTDTQKDILIKNLDKIKSNYSLAQT
                     QKKFILKNSQEAKDVLEKIIPELNTLAKETSNLAATNDELKKQSAETDGVLQKVKQGV
                     DDVRNTKSSIYTDFIAILGVFSAFVFVMFGGIDVARAIFDIGNDLQTLDLSRMITVSS
                     LMLIGVLTLMYSLLLWVARITGKNFGNCYSSKCDNGCRHKWRHFLMRHSFYFSLMFLL
                     VLTTVVSHCLFK"
     gene            complement(1832..2266)
                     /locus_tag="VB649_001654"
     CDS             complement(1832..2266)
                     /locus_tag="VB649_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670587.1"
                     /translation="MKRSKKASLLSVIVGMALAVIPIYIVNYDNELIVLLMSIFFNGI
                     IVSAFELIKTYDGLQEEYKKLTVDRWKNTILLAFNSLYFASILTNSLSNNLSTILSTN
                     RSDKVSAIFLTGCSILALLPFLLHRLIKREIEIENERKKLKK"
     gene            complement(2538..3338)
                     /gene="sda3"
                     /locus_tag="VB649_001655"
                     /gene_synonym="mf3"
     CDS             complement(2538..3338)
                     /gene="sda3"
                     /locus_tag="VB649_001655"
                     /gene_synonym="mf3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptodornase Sda3"
                     /protein_id="HEP1670588.1"
                     /translation="MSKSNRRTWQGLVVILIAILTTFTTSTVTAARKIRNFPDTTEIL
                     LGTKATETPGILPFTGSYQLVLGDLDNLQRPTFAHIQLKDQDEPNIKRKGLKFNPPGW
                     HNYKLTDANGKTTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDSWLALHPNFWLDYKVTPVYHKNELVPRQVVLQYVGIDENGDLLQIKLGSEKES
                     VDNFGVTSVTLDNVSPLAELDYQTGMMLDSTQNEEDSNLETEEFEEAA"
     gene            3576..3758
                     /locus_tag="VB649_001656"
     CDS             3576..3758
                     /locus_tag="VB649_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEP1670589.1"
                     /translation="MLTYDEFKQAIDRGYITGDTVMIVRKNGQIFDYVLPHEKVKNGE
                     VVTEEIVEEVMVELDK"
     gene            complement(4025..5179)
                     /locus_tag="VB649_001657"
     CDS             complement(4025..5179)
                     /locus_tag="VB649_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP1670590.1"
                     /translation="MPISYLKISTPQRKERGKTMIEKYTKKDGTTAYRLRAYLGVDPV
                     TGKQVRTTRQGFKTEREAKRAEVKLIDDFQRQGAWKSNDKTTFDDVAKLWFEQYQNTV
                     KPSTFLVNQNYYKTILKPHLGQLQMTKITVMICQKFVNCLSRYSGYTLYLSLANRIFK
                     FAVNLGIIDNNPMNKTLRSKCTYKNVDTLTKKYYTKEELNTFLRLVEAEETLEMRLIY
                     RLLSYGGFRIGELIALKDTDFDFRNNTISITKTIAYTKEGWAVQSPKTKKSNRTISMD
                     AETMSLAKLYIKQSIKPLHGSFKLFNFSCDTVRNRLDKLILKHGLKRITPHGFRHTHA
                     SLLFEAGIPAKIAQERLGHAKIAITMDLYTHLSKKSKDDVADKLAELVAV"
     gene            complement(5298..5819)
                     /locus_tag="VB649_001658"
     CDS             complement(5298..5819)
                     /locus_tag="VB649_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670591.1"
                     /translation="MKKIVYLFTLSVLIVCLGACTGGSKKDTTSKTPSSDTSKVSGDM
                     SEKEYFDTLISKIDKVTTDNYKSDEYLFYDYKTILRDPKKYFSLKVRINNLKIIQISD
                     KDKYTKMLANTPNGDLYMLFIETKRLETKLLETDNITINGRYLLSYEYTTTSGSENSV
                     PLIYIDGYLLLDK"
     gene            complement(5830..6210)
                     /locus_tag="VB649_001659"
     CDS             complement(5830..6210)
                     /locus_tag="VB649_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEP1670592.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNIPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQ
                     FMEKYELTSIADEVMVKEEFKNLI"
     gene            complement(6224..6583)
                     /locus_tag="VB649_001660"
     CDS             complement(6224..6583)
                     /locus_tag="VB649_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670593.1"
                     /translation="MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTA
                     NTDPIEKIANYFNVSTDYLLGRTDNPKMAQDGHTSVAIDLKKDAEETFFFDGHELNDE
                     DIDLITSILETRIKNRK"
     gene            7379..7570
                     /locus_tag="VB649_001661"
     CDS             7379..7570
                     /locus_tag="VB649_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670594.1"
                     /translation="MPDNAIAIEKIKKYLLDNNLKQVDLAVTYGKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            7581..8309
                     /locus_tag="VB649_001662"
     CDS             7581..8309
                     /locus_tag="VB649_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEP1670595.1"
                     /translation="MNNLITVTLNENQEPIVSGRDLHQALEIKTQYTKWLERMSDYGF
                     EENEDYVAISQKRLTAQGNQTEYTDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKD
                     FNSPEKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQN
                     GVNIGQNKLFQWLRANGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNV
                     TPKVTGKGQQYFINKFLNQEYLPV"
     gene            8342..8491
                     /locus_tag="VB649_001663"
     CDS             8342..8491
                     /locus_tag="VB649_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670596.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGIRLVETKEFHPVS
                     GTLLD"
     gene            complement(8488..8688)
                     /locus_tag="VB649_001664"
     CDS             complement(8488..8688)
                     /locus_tag="VB649_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEP1670597.1"
                     /translation="MQRQYVSSSNAQSVDWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            8677..8931
                     /locus_tag="VB649_001665"
     CDS             8677..8931
                     /locus_tag="VB649_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670598.1"
                     /translation="MTLHNFSSFRNDSFIIARRRNYTDRKENHMRPKRYPYSGKKNRK
                     AKDISLKLMSKEELSDFSRQIAEATRDSVEPFREPQSMMS"
     gene            9177..9434
                     /locus_tag="VB649_001666"
     CDS             9177..9434
                     /locus_tag="VB649_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670599.1"
                     /translation="MQSQLTYDLLKKQIAEELFDEFKKLIQEKDLANQWVNQTTLVNE
                     YGYSWQTIKRMESYGLKSFKNGKDKMYCLADVNEIKHLMKQ"
     gene            9463..9648
                     /locus_tag="VB649_001667"
     CDS             9463..9648
                     /locus_tag="VB649_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670600.1"
                     /translation="MNKLELFLLTTTIILAIIARIQYEVIKKHNSPENKRRIFREVAL
                     ENSKGWNEKRSRGGVIS"
     gene            9742..9999
                     /locus_tag="VB649_001668"
     CDS             9742..9999
                     /locus_tag="VB649_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEP1670601.1"
                     /translation="MLLTILRNKEEWRVYPEELAKRHSDGLASVRAGLKELEQAGYVR
                     TYKKIIRRSDGLQHYRFCSDCKISDETYKQLVEQIERELSD"
     gene            10121..10531
                     /locus_tag="VB649_001669"
     CDS             10121..10531
                     /locus_tag="VB649_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEP1670602.1"
                     /translation="MMKKKGEPVDKKELFDNFQNNWMRLLSPFEIEDINKWIDEEKMP
                     VEVVNEALKSTILYNAPNLRYLNRVLNNWKRQGIDTVEKVEFARLQFENKKLSQGKGQ
                     LSNVPSWSNPDYRDPTYDDLKVNPSEVSDGSGDF"
     gene            10512..10724
                     /locus_tag="VB649_001670"
     CDS             10512..10724
                     /locus_tag="VB649_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670603.1"
                     /translation="MDQEIFNGFNILLKKMYGKQASIETFNQFIEYCQRGKEVNGVRP
                     VLNPVNLYAFGLSITTLEAMKIYRER"
     gene            10879..11085
                     /locus_tag="VB649_001671"
     CDS             10879..11085
                     /locus_tag="VB649_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670604.1"
                     /translation="MTPEQAEKAKIRAKQELETFSIYLDQAIDELGGVLTSREVFLAA
                     GITYLGAGQTDIHAAVEGLCEQIQ"
     gene            11141..11470
                     /locus_tag="VB649_001672"
     CDS             11141..11470
                     /locus_tag="VB649_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670605.1"
                     /translation="MNIKEKIVVLRNTEDGSFLKSFKNRDGALAYNVELTDSIQLASF
                     LPEEFYNMQKDKIDNLAETFGYDVVVIEASYDLKFIDGESVPELTKEQKVKSMVNGMF
                     EQIFGGE"
     gene            11473..>12144
                     /locus_tag="VB649_001673"
     CDS             11473..>12144
                     /locus_tag="VB649_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEP1670606.1"
                     /translation="MANQLSTYTHKQFFNAPTVQKAFDDVWKGAGTQFAVSILSVLQG
                     SQSLKSASNKSIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLFNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIDEDNQDST
                     ISTPKD"
BASE COUNT         4083 a         2008 c         2229 g         3824 t
ORIGIN      
        1 tctgacacta tcgtagagac agcaaaaaca ggcaccttta cccttgatgt tgcagagatc
       61 aatatcagac gctggccaag tctagccagc gaggttgtag gtatctacaa gcaaggtgat
      121 actgtcagct ttgatagcga gggctacgct aatggctatt attggattag ctatgttgga
      181 ggcttaggta tgcgtgacta cctagctatt ggacagactg ataaagacgg gaaccgcatc
      241 agtatttggg gtaaattaaa ttagataaga caaatgccct cgctttttgc gggggctgtt
      301 ttttggtatc ctaatcaaga tgtagtgtta gctaactttt tagctaacaa gatatagtac
      361 ttgacaaata tgttataatt aagaaaaagg aggtgtaatt gagatgcatg cgttatttgt
      421 tgcaaattat ataattgagt attcaaataa aaaaggctac aaaattaata accttaaatt
      481 gcaaaaatta ttatacttcg ttaatgtaag aaacattctt gaaaatggag ctccgctttt
      541 tgaagagagt atggaaaagt ggaagtatgg accggttgtt cctgatgtct atcatgaata
      601 taaacgtttt ggagcttttt ccatttctac agacgagatg attatggaat atgttgaatt
      661 cagcgtcagc ccattcgggg agttatctga cttagagata actgaatatg actcacaaaa
      721 agtagagaat actcaattga ttgagaatac agttgatgct ctgcatgggt tcggtccgtt
      781 cgaacttgtt gatattactc acgaccatac accttggaaa aagtatgagg atagaataat
      841 ggacggtgtc caaggaatta aatatacaat cgaagaaata aaagactttt ttggacataa
      901 tccaggggct aaaatatggg tacaatagct ccagcgttta tggaattatt actagatgct
      961 aatttttgca aagcaccagt aaataatcaa gacactttat taaaggttta tcatagggaa
     1021 atggctaaag ataatgtcac aattccttat gaaataattg ctgaatatgt gtatagtcac
     1081 gaagatagcg ttgaagaaaa tgagaaatta aactcaaata tcgactttat tatttcggaa
     1141 ttttcaggga ctgatacaca aaaagatatt ttgataaaaa acctcgataa aataaaaagc
     1201 aattattcat tagctcaaac tcagaaaaaa tttatactta aaaactctca agaagctaaa
     1261 gatgttctgg agaagattat ccctgagcta aacacattag caaaagaaac ttctaacctt
     1321 gcagctacaa atgacgaatt aaaaaaacaa tccgcagaga ctgacggtgt tttgcaaaaa
     1381 gttaagcaag gagtggatga tgttcggaat acaaaatctt caatctacac agactttatt
     1441 gctatcttag gagtgttttc agcttttgtt tttgttatgt ttggtggtat agatgtagca
     1501 agggcgatat ttgacattgg taatgatctt cagactcttg atttatcaag gatgattact
     1561 gtctcaagtc taatgctaat cggtgtattg acattgatgt attctttgtt gctgtgggta
     1621 gctagaatta caggtaaaaa ttttggtaac tgctattcgt caaaatgtga taatgggtgt
     1681 cggcataaat ggcgtcattt tctcatgaga cattcatttt atttttcttt aatgttctta
     1741 cttgttttaa caactgtagt tagtcactgt ctctttaaat aaaaagccaa ccgctctctt
     1801 gattgagggc ggttttttgt gttataagta attatttttt taattttttt ctttcatttt
     1861 caatttctat ttctcgtttt attaacctat gaaggaggaa tggaagtagt gctaaaatag
     1921 aacaacctgt aagaaatatt gcacttactt tgtcagaacg attagttgat aaaatggtcg
     1981 ataaattatt tgatagacta tttgtcaaaa tagaagcaaa atataatgaa ttgaaagcca
     2041 gtaaaatagt attcttccat ctatctacag ttagcttttt atattcttcc tgcaaaccat
     2101 catatgtttt aataagttca aaagcggaaa caattatccc attaaaaaaa atactcatta
     2161 aaagaacgat aagttcattg tcataattaa caatataaat tggtatcaca gctaaagcca
     2221 ttccaacaat aacactaagt aacgatgctt ttttggacct tttcataaaa tcaccctttt
     2281 tctttcaatc tactatacat attactcgat tcaatcatcc tcaacaaagg ccgttaaaac
     2341 agactaattt ctcaaagtcc tatttaaggg actttctaaa tagacgttgt ttttttaaaa
     2401 aatagcacag atagtagcct atactaattt ttcttcaaaa tttaacttta tacaaattac
     2461 cccaaatatt aaataaataa tctaacattt gggataatgt tcacaatcta gatattttta
     2521 ttaagtataa gtttatgtta agccgcttct tcaaactctt cggtttctaa attactatct
     2581 tcttcgtttt gagttgaatc tagcatcatt cctgtttggt aatccaattc agctaaagga
     2641 gatacgttat ctaatgtaac tgatgttact ccaaagttgt ctacactttc tttttcacta
     2701 cctaacttaa tttgaagtag atctccattt tcatcaattc caacatactg tagaactact
     2761 tggcgaggaa ctaactcatt tttatgataa acaggagtaa ctttatagtc tagccagaag
     2821 ttagggtgta gagctaacca gctatctaat ctattttcat aatagagcat tcctaaagga
     2881 tttttgtcac taaagccagt attaagatat tttgtcattg taactaggtt tttaggctcg
     2941 tcatttaagc cgctaaattg gtaaccaact aaatggccac ggtccattaa ccaagttgtt
     3001 tttccattag cgtcagtcaa tttgtaatta tgccagccag gaggattgaa tttaagtcct
     3061 tttcgtttaa tattaggctc atcttgatct tttagctgga tgtgtgcgaa ggttggcctt
     3121 tgcagattgt caagatcgcc caaaactaat tggtagctac cagtgaatgg taagattcct
     3181 ggtgtctcag tcgccttcgt tcctaacaaa atttccgtgg tatcagggaa atttctaatt
     3241 tttctggctg ccgtaacagt acttgtggta aaagtggtga gaatagctat taaaataaca
     3301 actaaacctt gccaagtacg acgatttgat ttagacatat ccatgtcctc cttttattat
     3361 ttacaggtta attatatcac tttaaattaa aaaaacttaa aattaataaa attgatttat
     3421 caataatatt acgctaaaat ttctttttat ttaatattcg ctaacaatca atattttagt
     3481 ttgtaacaaa aaagatgtta attaaattta aacgaccttt aaatttaatt atattatttc
     3541 ctgtaaaata cgaataaata agtaggaggg taaaaatgct aacatacgac gagtttaaac
     3601 aagcgattga ccgtggatat atcacaggag acacagttat gatcgtgcgt aaaaacggac
     3661 agatttttga ttatgttttg ccacatgaga aagtaaaaaa tggagaagtt gtgaccgagg
     3721 agatagtgga agaagtgatg gtggaattag acaaataaaa aagacttttc caagtccaaa
     3781 atcagatgct ccccagcgga aaattactac gttatttact acgttatttt aaaaatcagt
     3841 gtaattgact agataatgta aggttgtaaa atgttgattt atcaagtgat tgggcaatga
     3901 tagcaaatga taccatatta aggttctttt ttgttataat ataaggttac ctctcagaac
     3961 cattgatacc aaggcttttt aaaagtctaa aacccgactt actacgtttt ccgctacgtt
     4021 tgtgttaaac agcgacaagt tcagccaatt tgtcagcaac atcatccttt gattttttgg
     4081 acaagtgagt atataaatcc attgtgattg ctattttagc gtgacctaac ctctcttgtg
     4141 caatcttagc gggaatccca gcctcaaaca gtaacgaagc gtgggtgtgt ctaaacccgt
     4201 ggggagtaat cctttttaat ccatgcttca atataagttt atccagtctg tttctcacag
     4261 tgtcgcaaga aaaattaaac aatttaaacg atccgtgtaa aggtttgata ctttgcttaa
     4321 tatataattt ggctaacgac atggtctcag cgtccattga tatagtgcga ttgctttttt
     4381 tggttttagg agattgtaca gcccatcctt cttttgtata agcaatggtt tttgtaatgc
     4441 tgatagtatt gttgcggaaa tcaaagtcgg tatcttttaa agctattaat tcaccaatcc
     4501 taaaaccgcc ataactcagc aatctataaa tcagacgcat ctctagagtt tcttcagctt
     4561 ccacaagcct caagaaagta ttcaattcct cttttgtgta atattttttg gtgagtgtat
     4621 ccacgttttt gtaagtgcac tttgatctca acgtcttgtt cattgggttg ttatcaataa
     4681 tacctaagtt gacagcaaat ttaaaaattc tgtttgctag acttagataa agcgtatatc
     4741 cgctatatcg agacaggcaa ttcacaaatt tttgacaaat catgacagtt atcttcgtca
     4801 tttgcagttg ccctaaatgt ggctttaaaa ttgttttata gtaattttgg ttaaccagaa
     4861 atgttgacgg tttgactgta ttttggtact gctcaaacca cagtttagct acatcgtcaa
     4921 atgtagtttt atcattactt ttccaagcgc cttgacgctg gaaatcatca ataagtttta
     4981 cctcggctct tttagcttct ctttctgttt taaaaccttg cctagttgtc ctgacttgtt
     5041 taccagtcac gggatcaacc ccaaggtatg ctcttaagcg ataggcagtt gtgccatctt
     5101 ttttagtgta tttttcaatc attgtttttc ctctctcttt gcgctgggga gtgctgattt
     5161 tgagatagga tattggcatc acctcctttg tgtgatataa ttcagagtat aagaaaatga
     5221 gctatttaaa gcttacttct tattgattgc atattgcctt acgctctcct cgaccaaaat
     5281 ttgagcgtgg ggctttttta tttatctaaa agtaagtagc catctatata aattagaggg
     5341 acactattct cagaaccact tgttgtcgta tattcataag ataataaata tcttccattg
     5401 atagtgatat tatcagtttc taaaagttta gtttctagtc gcttggtttc gataaacaac
     5461 atatacaagt ccccgttagg ggtgtttgct agcattttag tatatttatc tttatcagag
     5521 atttgtatta tttttaaatt attgattctg accttaaggg aaaagtactt tttagggtct
     5581 cttaaaattg ttttgtagtc ataaaataga tactcatctg atttgtagtt atctgttgtt
     5641 actttatcaa tcttagatat tagagtatca aagtattctt tttcgctcat atctccagat
     5701 actttactag tatccgatga gggagtcttt gatgttgtat ctttttttga gccaccagtg
     5761 caagctccga gacatactat taagactgat aaggtaaaca aatatactat ttttttcaca
     5821 ataaatcccc taaattaaat ttttaaattc ttctttaacc atcacttcgt cagcgattga
     5881 ggtcagttca tacttttcca tgaattggat gtagttgaaa tcctccatat tatcccaata
     5941 ggatagctct tcttttaaga gatgatgtat catacaccta tcagcttgta gctctgcttt
     6001 ttctttgttt agcttgtaat aactcgcagt atgttctcta tgtcctagtt cgtgatagat
     6061 gactttgtgt ttatatatac cgtcaagata agtgtcaatc gcaatgacgt tgtgtttttt
     6121 attaaacatt ccagggatat ttgtacccct accgtcaaag taaactaaat cgattccttt
     6181 ttcctggcag actgtttctg gtgtcatcat agagctgccc tctctatttt ctatttttga
     6241 tgcgcgtttc caatatagat gtgataaggt ctatatcctc gtcgttgagt tcgtgtccgt
     6301 cgaagaagaa ggtttcttct gcatcttttt ttagatcgat tgcgaccgaa gtgtgcccat
     6361 cttgagccat cttaggatta tctgtcctgc caagtaaata gtcggtagaa acattaaagt
     6421 agttagctat tttttctatt gggtctgtat tagccgtttt tttacttttt aaattataaa
     6481 tgtagttttc actcagccct atatcagttg cgaccttttg gagagatact cctctttttt
     6541 tagctaaggc ttcaattctt gaatacacct caaacattgt catatcaacc tttctgaaag
     6601 tatgacaaaa aaaatttaac tttttcgagt aaaaaatatt gacttagttt acacgataga
     6661 gtaaaatagt ttttgtaaga tagttagtta gtaaaaaacg aagttaaact ttttacaaat
     6721 cttttaaaag tagttgggga actgcgcaat ataaaagagt tataaaggtt ataactaggt
     6781 ttttcttatg ccttcatttt acattaacgt gtaaaataag tcaacacaaa aatgttattt
     6841 ttttactaac tttcttgctt acaaaaataa aacaccacct agctgctatc tagatggtgc
     6901 tacggaaatt attctgctca ataaaaaaca ctctccgtta ttacacattg gaaagtgttt
     6961 acaagttttt attaagactg agcaacaggt gtaaactgtt ggctgaaact tcgtcggtcc
     7021 tgcttccgac actgctttca gcatgtataa gctagtcctt ggacgccact cggcagttat
     7081 ctgacaggcc tgctataagt cgcgctgcag tcgcccttat agtcagcgtc aggctccgtg
     7141 tgttaaacgt cttcgataaa aaacattgtt gttacctagc ttatataact catctagtca
     7201 cagtaccttt caaaaatttt gccaatttac atcaactcct tttttgtaat aaaggtactt
     7261 tcattataag gttgtaagtc aaaaaaatca agatggttac aaaaatcatt gagcagaata
     7321 acgatttccg tatattttat taatattttc tacttatttt tgaaaaggag gtatataaat
     7381 gccagataac gcaatcgcca tcgaaaaaat aaagaagtat ttgcttgata acaatcttaa
     7441 acaagttgat ctagcagtta cttatggcaa agaaccgcaa gatgtggcga atattcttgc
     7501 tggacgaaaa aaagacccag catcaaatcg ctttgtctta aaagttattt cggatttaaa
     7561 aatcagatag aaggaataat atgaataatc ttatcacagt aacactaaac gaaaaccaag
     7621 aacctattgt ttctggtcga gatttgcatc aagcattaga aattaaaact cagtacacaa
     7681 aatggttaga acgaatgtct gattatgggt ttgaagaaaa tgaagactat gtagctatta
     7741 gtcaaaaaag actaacagct cagggcaatc aaacagaata tacagaccac gttctaaaac
     7801 tagacatggc taaagaaatt gcgatgcttc aacggaacga aaagtctaaa caagtccgca
     7861 aatactttat ccaaatcgaa aaagacttca acagccctga gaaaatcatg gcaagggcgt
     7921 tgctgatggc ggataagaaa gtgcataaac ttgaagcaca aatcgaggca gaccgtccca
     7981 aagtactatt tgctgatgct gtaagtgcta gcaaatcatc ttgtctgatt ggtgagttag
     8041 ctaaaatcct gaaacagaat ggagtcaata ttggtcagaa taagctattt cagtggttac
     8101 gagccaacgg ctacctaatc agtcgccgtg gtgagtcttg gaatcagcca acgcaaaaaa
     8161 gtatgcagct tggattgttt gaactcaaaa aaacagccat caatcactct gacggtcaca
     8221 ctacaacaaa tgtaacccca aaagttactg gtaaagggca acaatacttt attaataaat
     8281 tccttaacca ggaatatctg ccagtttaga aacgtaacaa aactaacgaa gggagaaaag
     8341 tatgccagag gatttaatca aacaactaga agctggttca gaatttctag caaagacatg
     8401 tttacatagc aagattatta tcacggtgga tggtattcgg cttgtggaaa caaaagagtt
     8461 ccacccagtg agcggaactc tactagatta gacaatacgt gtataagtgt gtatcttagc
     8521 taatctatga atatttgagc caacagaccc aacaagaaca gaacggtatt ccgtttggct
     8581 tacattgtga taatggtaaa tagaaccatt attaaactca acttccaaag tgttattttc
     8641 ccaatcaaca ctttgggcgt tactagatga aacgtattga cgttgcataa cttttcctcc
     8701 tttcgtaatg atagctttat tatagcacgc aggaggaact acacagatag aaaggaaaac
     8761 cacatgagac caaaacgata tccgtatagc gggaagaaaa acagaaaagc aaaagacatc
     8821 agtctcaagc tgatgtctaa agaggagtta tctgatttta gtcgtcagat tgctgaagcc
     8881 actcgtgata gtgtcgaacc atttcgagag ccgcaaagta tgatgagcta agtattaact
     8941 tttcaaggtt tacagatccc ccttcgcttt ctttcgcata tctattgtaa tggtactcaa
     9001 taacttccag aatttcttcg gttttaccat tgcttagaga ttgggcgaaa ttgttgaaat
     9061 ctttattcat ataatcacct cctttcgaga tgattatatc aaaaaaagtc cgacggcaat
     9121 cggactctaa agaatactat ttacttagat tataccacga aaggggtgat aaatctatgc
     9181 aatcacaact tacttacgat ttactaaaaa agcagatagc agaagagctt tttgatgagt
     9241 ttaagaaact catacaggaa aaagatttag cgaatcagtg ggtcaatcaa acaacgctcg
     9301 tcaatgaata cggctactca tggcaaacta taaaacgcat ggagagctat ggccttaaat
     9361 cttttaaaaa cggtaaagac aaaatgtatt gtcttgctga tgtcaacgaa atcaaacact
     9421 taatgaaaca ataagcgctg gggagtgcta gaggagcgta acatgaacaa attagaacta
     9481 tttttattaa caacaacgat tatcttagca atcattgcaa gaattcagta tgaagtcata
     9541 aaaaaacata attcaccaga gaataagcga agaattttta gggaagtagc tttagaaaac
     9601 agcaaagggt ggaacgagaa gcgctctaga ggaggggtga tcagctaatg cagtacattt
     9661 ttcaagacgc tacgaggtaa ttttactagt gttagcaatg aatttataga tgacaataac
     9721 ttgtcatata aagcagtagg tttgttattg acgatattga gaaataaaga ggaatggaga
     9781 gtatatcctg aggagcttgc aaaaaggcac tcagatggac ttgcatcggt tagagcaggt
     9841 ctaaaagaac ttgagcaagc tggatatgtc agaacctata agaaaatcat caggcgatca
     9901 gatggtttac aacattatcg tttttgctca gattgtaaaa taagtgatga aacctacaag
     9961 caattagttg agcagataga aagagaactt tctgactaaa atgcgatttt ctaaagttag
    10021 aaaatctaaa gttagaaaat ctaaagttag aatttcgcac actaataaat actaacatta
    10081 aataaatact aaataacaat aaatactaac agacaataag atgatgaaga agaaaggaga
    10141 gccagtggac aaaaaagaac tgtttgataa tttccaaaat aattggatgc gtctcttatc
    10201 cccgtttgag attgaggata ttaacaagtg gattgatgaa gagaaaatgc ctgttgaagt
    10261 agttaatgaa gcactaaaat cgacaattct atataatgca ccgaacctca gatatttaaa
    10321 cagagtgcta aataactgga aacgacaagg gattgataca gtcgagaaag tcgaatttgc
    10381 taggttgcaa tttgaaaata aaaagctaag tcaaggtaaa ggtcaacttt ccaacgtccc
    10441 aagctggtcg aatccagact atcgagaccc gacgtatgat gatttaaaag taaatccaag
    10501 cgaggtatca gatggatcag gagattttta acggatttaa tatcttactt aaaaaaatgt
    10561 atggtaaaca agctagcata gagaccttta accaatttat cgagtattgc caaagaggaa
    10621 aagaggtaaa cggggttagg cctgtattaa atcctgtcaa tctatacgca ttcggtctta
    10681 gcattacaac gctagaagct atgaaaattt atcgcgagag gtaattgaca tgacaaaaca
    10741 acatagagag acgcttatct ggtacagagc aagccatcaa gagcgtgaga gattgcttga
    10801 tttcgggctt gttgataaat cacagtacat gacactattg cggcaattgc gcaagaaata
    10861 tgcgatttag gaggaaatat gacaccagaa caagcagaaa aagcaaaaat cagagctaaa
    10921 caagaacttg aaacgtttag catatacctt gatcaggcaa ttgatgagct cggtggagtt
    10981 ctaacttcac gagaagtctt tttagcagcg ggaataacat atcttggcgc aggtcagaca
    11041 gatatacatg ctgcagtcga gggattatgt gagcaaatcc aatgatttta aatttagtga
    11101 agactgggag agcaactaaa acacaaaaag aggaaatgaa atgaacatca aagaaaaaat
    11161 tgtagtgcta agaaacactg aagacggaag ttttttaaag agttttaaaa atagagatgg
    11221 agcgcttgct tataatgtgg aacttacaga tagcattcag ctggcatcat ttctaccaga
    11281 agaattttac aacatgcaaa aagataaaat cgataattta gccgaaacgt ttggatatga
    11341 tgttgtagtt attgaagcat cttatgacct aaaatttatt gatggcgaat cagtgccaga
    11401 gttaacaaaa gagcaaaaag ttaaaagtat ggtaaatgga atgtttgagc agatttttgg
    11461 aggtgaatag agatggcaaa tcaattatca acatacacac acaaacaatt ttttaacgca
    11521 ccaacagttc aaaaagcttt tgatgacgtt tggaaaggcg ccgggacaca gttcgcagta
    11581 agcatcttgt cagtactaca aggtagtcaa agtttgaaat cggcatctaa taaatctatt
    11641 tatgcagcag ctatgaaagc agccgtgtta aatctgccta ttgagccaag cttaggaagg
    11701 gcctatttag ttccgtacaa aggtcaagca caattccaat taggctataa agggttgatt
    11761 gagttagcgc agcgcagcgg acaatacaaa aatattaatg caggtatcgt ctataaatca
    11821 caattaattt cttacaaccc tttgttcgag gaattaatcc ttgactttag caagccacaa
    11881 gatgaaattg tagggtattt tgccgctttt aaacttttca atggattcga gaaagtttct
    11941 ttttggacag tagaaaaagt aactgcacat ggaaagaaat tttcaaaatc gtttgctagc
    12001 ggtccttgga aaacagactt tgatgcaatg gctcaaaaaa ctattttaaa agatattttg
    12061 agtaaatatg gtccgttatc agttgagatg cagaaagcta tcgatgaaga caatcaagat
    12121 tcaacgattt ctactccaaa agac
//
LOCUS       DATTYN010000040         9968 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.40, whole genome shotgun sequence.
ACCESSION   DATTYN010000040 DATTYN010000000
VERSION     DATTYN010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9968
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.40"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            28..2040
                     /locus_tag="VB649_001674"
     CDS             28..2040
                     /locus_tag="VB649_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HEP1670607.1"
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGAL
                     DNTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANS
                     ALLQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEH
                     EASHQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQ
                     NYEHYQFLDVAETIAKYAKELQEQHVHAIVVLAHVPATSKDGVVDHEMATLMEKVNQI
                     YPEHSIDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFMTTPSAN
                     VVTVAPGIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNL
                     VTTAQLTIAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQM
                     TGQHIYDVLNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLT
                     TTYTVVVNDFLYGGGDGFSAFKKAKLIGAINTDTEAFITYITNLEASGKTVNATIKGV
                     KNYVTSNLESSTKVNSAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSLGKKE
                     TTTNKNTISSSTLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     gene            complement(2122..2532)
                     /locus_tag="VB649_001675"
     CDS             complement(2122..2532)
                     /locus_tag="VB649_001675"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEP1670608.1"
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGM
                     AANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITV
                     EYLDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            3249..3326
                     /locus_tag="VB649_001676"
                     /pseudo
     CDS             3249..3326
                     /locus_tag="VB649_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(3424..5301)
                     /locus_tag="VB649_001677"
     CDS             complement(3424..5301)
                     /locus_tag="VB649_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEP1670609.1"
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTT
                     LLDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDAASVLDTVLSADVKAIQLIRQ
                     YELLMANYTEDKQESLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGM
                     RRRVQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHV
                     ATRIFELDKAGLTEYQGNYQDYVRLKAEQDERDAANLHKKKQLYKQELAWMRTQPQAR
                     ATKQQARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLFKD
                     FNLIIQNKDRIGIVGDNGVGKSTLLNIINGDLKPTSGKLDIGDTIRVGYFSQQLKDMD
                     ETKRVINYLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLK
                     LLIEKPNVLLLDEPTNDLDIATLTVLENFLANFVGPVITVSHDRYFLDKVATKILAFE
                     EGDIRIFYGNYSDYLDEKAFEKETVEADLAKAIVTEEVPLPPKEEKKRMSYLEKQEWA
                     QIEDKIATIEANIEEIENQMLTVVSDYDQLAQLQKELDQHNNDLLLAYERFEYLSRLD
                     I"
     gene            complement(5298..6506)
                     /locus_tag="VB649_001678"
     CDS             complement(5298..6506)
                     /locus_tag="VB649_001678"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEP1670610.1"
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLGRPIH
                     DVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDA
                     LRIMRGFRFAASLDFDIEATTFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGIS
                     AMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDYHQAWAYVMISLAIEDPKSFLK
                     AWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEDLRKAQSLSVDMDR
                     INTLDQALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTI
                     EAFVREELAT"
     gene            complement(6631..7479)
                     /locus_tag="VB649_001679"
     CDS             complement(6631..7479)
                     /locus_tag="VB649_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEP1670611.1"
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLS
                     IDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQF
                     LAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEIL
                     NDLIADGQYNVFIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAF
                     GVTPRL"
     gene            complement(7479..7859)
                     /locus_tag="VB649_001680"
     CDS             complement(7479..7859)
                     /locus_tag="VB649_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEP1670612.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDE
                     QQKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGIHLEFKN"
     gene            complement(8087..8263)
                     /locus_tag="VB649_001681"
     CDS             complement(8087..8263)
                     /locus_tag="VB649_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006532627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670613.1"
                     /translation="MIKPYGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDE
                     ALVINLFILDLKLT"
     gene            8764..9789
                     /locus_tag="VB649_001682"
     CDS             8764..9789
                     /locus_tag="VB649_001682"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922160.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEP1670614.1"
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIRYSEVT
                     PYHVTSVWTKGVIPPAKFTQGEDVFHTPYVANQGWYDITKTFNGKDDLLCGAATAGNM
                     LHWWFDQNKEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKA
                     FPGLSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGD
                     QSKLLTSRHDFKEKTLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSN
                     GNLKAIYVTDSDSNASIGMKKYFVGVNSAGKVAISAKEIKEDNIGAQVLGLFTLSTGQ
                     DSWNQTN"
BASE COUNT         3195 a         1979 c         1621 g         3173 t
ORIGIN      
        1 gattacgtta acttattagg agattttatg aaaaaatatt ttattttaaa aagtagtgta
       61 ttgagtatcc tgactagttt tactctatta gttacagacg ttcaagcaga tcaagttgat
      121 gtgcaattcc ttggcgtcaa tgattttcac ggcgctcttg ataataccgg aacagcttac
      181 acaccaagtg gtaaaatacc aaatgctggg acggctgctc aattaggtgc ttatatggat
      241 gacgctgaga tagatttcaa gcaagcaaat caagacggaa caagtatacg tgttcaagct
      301 ggagatatgg tcggagccag tcctgctaac tctgcacttt tacaagatga gcctactgtg
      361 aaagtcttta acaaaatgaa atttgaatat ggcactcttg gtaatcatga atttgacgaa
      421 ggactagatg aatttaatcg tatcatgaca ggtcaagcgc ctgatcctga atcaacaatt
      481 aatgatatca ccaaacaata tgagcacgaa gcttcgcatc aaaccatcgt cattgctaat
      541 gtcattgata aaaaaaccaa tgatatcccc tatggttgga aaccttatgc tataaaagac
      601 atagccatta atgacaaaat cgttaaaatt ggcttcattg gtgttgtgac tacagagatt
      661 ccaaatctcg ttttaaagca aaactatgaa cactatcaat ttttagatgt agctgaaacc
      721 attgccaaat atgctaaaga actacaagaa caacatgttc atgctattgt ggttttagct
      781 catgttcctg caacaagtaa agatggtgtt gttgatcatg aaatggctac gcttatggaa
      841 aaagtgaacc aaatctatcc cgaacatagc attgatatta tttttgcagg acataatcat
      901 caatacacta atggaactat cggtaaaaca cgtatcgttc aagccctctc tcaaggaaaa
      961 gcttatgcag atgtccgtgg aacgctagat actgatacca atgattttat gacaactcca
     1021 tcagcaaatg ttgttactgt agcaccaggt atcaaaacag aaaattcaga tatcaaagct
     1081 ataataaatc atgctaatga tattgttaaa acagttactg aacgaaaaat cggaactgca
     1141 actaattctt caactatttc taaaacagaa aatattgata aagaatctcc tgtcggtaac
     1201 ttagtaacaa cggctcagct tactattgct aagaaaactt ttccaactgt tgactttgct
     1261 atgaccaata atggtggtat tcgaagtgac ctagttgtca aaaatgaccg gaccatcacc
     1321 tggggagctg cacaggctgt acaaccattt ggtaatatcc ttcaagtcat tcaaatgact
     1381 ggtcaacaca tttacgatgt cctaaatcag caatacgatg aaaaccagac ctattttctt
     1441 caaatgtcag gtttaacata cacttataca gataatgatc ctaagaactc tgataccccc
     1501 ttcaagatag ttaaggttta taaagacaat ggtgaagaaa ttaacttaac aactacttac
     1561 accgttgttg tcaacgactt tctttatggt ggtggtgatg gcttttcagc atttaaaaaa
     1621 gctaaattaa tcggagctat taacacagat actgaagctt tcatcacata tatcacaaat
     1681 ttagaagcat caggtaaaac tgttaatgct actataaaag gggttaaaaa ttatgtaact
     1741 tcaaaccttg aaagttcgac aaaagttaat agtgctggta aacacagtat cattagtaag
     1801 gtttttagaa atcgtgatgg caatatagtg tctagtgaag tcatttcaga ccttttgact
     1861 tctactgaaa acactaataa cagccttggc aaaaaagaaa caacgacaaa caaaaatact
     1921 atctctagtt ccactcttcc aataacaggg gacaattata aaatgtctcc tattatgaca
     1981 atccttgcct tgataagctt aggtggacta aacgctttta ttaaaaaaag gaaatcctag
     2041 cgtttactag taatcgatca cccttatata atcaggcatc tttgccaaaa aaacctaaag
     2101 cgtcctactc taggtttttt gttaaattaa aataccttct agatgatcta attcgtgctg
     2161 gcatatttga gcagttaagc ctgttaagct taatcgcttt ggtcgccaat tatggtccaa
     2221 atactcaaca gtaatcttat cataccgctg tgttttgcga tagccagata acgacaaaca
     2281 agattcttta gtttggtaaa ttcccttttt agaaaccatc acaggattaa acataaccaa
     2341 atcaataaat cccatactca caataacaat gcgcttttgt tcaccaatca tattggcagc
     2401 catcccaaga cattcctgtc tataaaaggc taaggtatct tgtaaatctt ggccaatcca
     2461 tagatcttct ttcttggcga cttgcgcttt ttgctgtaat aaaaaatgat ctgttatgat
     2521 ttctctaatc attcttatct ccttaaacct tctttttaat tcataaacta catgttcaat
     2581 ggactattat caccatagga tagacttagt atcatctgtt taaaacatca ggtgattcct
     2641 tatttcaaga tatcttgggc aactttatga aattctgcaa tatgagtacc aaataaaaat
     2701 tgacctgcat cagcagattg ttgctaagtt ctcatcacaa tattatcgaa tttactgtct
     2761 gcttcttcaa atgtctaaga gagatagtta ttgctttgtg agattttcaa accagatact
     2821 gctttctctt gcatttgcag ccttaacagg tccaaataaa acacctgctg tttgaaatgc
     2881 tttaatagct gatatgttgt taatagttag tattataaat tttctgaata tttctgtcaa
     2941 gtttttcagt tgacttaact tttttacttg atttttcctc acgtaataat agaaaagaag
     3001 cgccataatg taaactacac cccaaacgtt agataaaaaa atctaacgtt tggggtgttt
     3061 ttgtatgaca ttaagctatg aagataagct agatatttag cgctaaaaaa accgagggaa
     3121 ctccgtttga aagaagcatc tctgcaaaga agaagacaaa aaaccattat aaagaatgga
     3181 caaagacgag ttctgattag attttctttt aagaacggct aaagtgactc gttctaccta
     3241 ctattatcat cgattattgc aacaataaac gtatcaaaat aaaacgaaaa ggacttagtc
     3301 ctctacaaca cagaactaaa tcctttactt caaatagagt agccaacttt tggggctcag
     3361 tgcaagagca cttcttttct attatcactt gtttattata aacataacat taccatagta
     3421 ttcttatatg tctagtctac tcaaatactc aaaccgttca tacgccaata ataaatcatt
     3481 attgtgctga tcgagttcct tttgtaattg agctaactgg tcataatcgc taactacagt
     3541 taacatttgg ttttcaattt cttcaatatt agcctcaata gttgctattt tatcttctat
     3601 ctgagcccat tcttgttttt caaggtagga catgcgcttt ttctcctctt tcggaggaag
     3661 tggcacttct tcagtgacta ttgctttagc taagtctgcc tcaactgttt ctttttcaaa
     3721 agctttttca tcaaggtaat cactgtaatt gccataaaaa atacgaatat cgccttcttc
     3781 aaaagctaaa atcttagtgg ctactttgtc taggaaataa cgatcgtgac taaccgtaat
     3841 gactggtcct acaaagttag ctaaaaagtt ttctaagacc gtcaaggtgg caatgtctaa
     3901 atcatttgtt ggctcatcaa ggagaagaac atttggcttt tcaatgagca gttttagcaa
     3961 gtagagccgt tttttctccc caccagataa tttagcaatc agcgtgccat gacttgatct
     4021 cggaaaaaga aattgctcta aaagctcact gatactcgtt gttcccacgc ttgttttaac
     4081 ctcatcagcc acttcttgaa ggtaattaat gacccgtttg gtctcatcca tatctttgag
     4141 ctgctgagag aaataaccta cacgaatagt atctccaata tcaagcttcc cagaagttgg
     4201 tttgagatca ccgttaatga tatttaacag ggtagatttt ccgacgccgt tatctccaac
     4261 aattccaata cgatctttat tttgaataat caagttaaaa tccttaaaca actgtcggtc
     4321 gccataagca aaagaaaggt cttcaaagtg aatcaccttc ttcccaattc ggctcgtttc
     4381 aaaagccatc tccaatttat ctgcagaact gtcttggtga acttcttttt tcaagtcagt
     4441 gaaacgattg attctagcct gctgtttggt tgcacgcgcc tgtggctgcg tcctcatcca
     4501 agctaattct tgtttataga gttgcttctt cttgtgtaaa ttagcagcat ctcgttcgtc
     4561 ttgttctgct tttaagcgca catagtcttg gtaattgcct tgatattctg tcagtcccgc
     4621 tttatccaat tcaaaaatac gggtagccac atgatcaagg aaataacggt catgggtaat
     4681 aaaaaggacg gtttttttag ctgtcttgag ataggttgtt aaccaagcga tggtgtcaat
     4741 atcgagatgg ttggtcggct catccaacaa gagtaagtca gcagctccta gcaacacttg
     4801 agctaactgg acacgtcttc tcataccacc tgataggtct cccacttttt gttccaaatc
     4861 cgtgatgcct aattttgata ggactgtttt gacatcactt tcaatagacc aagcatctaa
     4921 gcgatccatt tcagacatga gggactctaa gctttcttgt ttatcctcag tataattcgc
     4981 catcaatagt tcgtactgac gaatcagttg aatagcttta acatcagctg ataataccgt
     5041 atctaaaaca gaagctgcat cgttaaattc agggtcttgt gttaagtaag cgattttgta
     5101 atcattggct ttagaaaatg gtgaatggtc tccgtcaaaa ccaagccttc ccgacaacac
     5161 atctaaaaga gttgtttttc ctgttccatt aaccccaata atcccaatac ggtcaaagtc
     5221 atgaataata aaggaaatat cttgaaagac ggtcttatct cccaccgttt ttgttaattt
     5281 ctccaccaaa aaatggctca tgttgctaat tcctctctaa caaatgcttc aattgtagtg
     5341 aaatcattat ctaggcgccc ctctacaatc gctaattcaa ctttctcaag cataagccct
     5401 agctgaggac ctggtttcat cccaaaatcc ttaatcaggt gagaaccatt aaggacgata
     5461 tcgtgtttgt catgaataac cagtgcctga tctaaagtat taatacgatc catgtcaacg
     5521 gataagcttt gagcttttcg gaggtcttcc actagactcg ccattttctt gccgtactgg
     5581 taaatatcca atttttcaaa agatctttcc tgacgaattc tataaagagc aatcaacttt
     5641 gtgacataac gctgaaaatc atttgaagtc ttccatgctt ttaggaagct tttaggatcc
     5701 tcaatggcta aactaatcat cacataagcc caagcttggt gataatcact aaaggtaaag
     5761 ttatctttca aagaaactat cagatgattc aagcctgctt cctgctgctt caagcctggt
     5821 aaatagtcgt aagcctgaca agcaatcatg gcagaaatcc cttttcgcca gtgcggtgcc
     5881 atcaataatt tatcaaattc agtaaaagaa cgttccacag aaattttttc caatagaggt
     5941 gaatggctcc tcatagcttc aaaagttgta gcttcaatgt caaaatccag actcgccgca
     6001 aatcgaaagc ctctcataat gcgtagtgca tcttcttcaa aacgttcctc tgctttaccc
     6061 actgctcgta accgtttttg ctttaaatca atgagtcctc taaatttatc aataacttga
     6121 ccattttcat ccaaggccaa ggcattgacg gtaaagtctc ttcgttttaa gtcttcctct
     6181 aaagagcgca caaaagaaac ctgactagga cgacgataat caacatagac atcttctgtc
     6241 ctaaaggttg tgatttcata ctcaccgcca ttttcaagca cgagcactgt accatgttca
     6301 atgccaacat cgacagttct gttaaaaatc gctttagtct cttcaggata ggaactagtt
     6361 gcaatatcta catcatgaat gggacgcccg agtaaaacat ctctgacgct tcctcccaca
     6421 aagtaggctt cataaccagc ttcttttatt ttagtcaata tgggtaaagc cttctgaaac
     6481 tcagaaggca ttgtcattaa tttcatacgt tgttttctaa cctatcatcc aactagccca
     6541 atctaaagtg tgattaggct acttgggttc tatcacattt tgttattgtt ttagtgattc
     6601 ttgcaattaa ctattttttc taatcgacaa ttaaagcctc ggtgttacgc caaatgcaat
     6661 ggctccttct cctaaatgag tagcaatcac cgctccaaaa tgaacctctt caatgtcata
     6721 ttgataacca ctgtcttgta agagtcgttt caaataatca gctttgtctt gtgcttttga
     6781 gtgaataata aacacattat actgaccgtc tgctatcaag tcatttaaaa tctcaaccaa
     6841 gcgtttcatg gctttctttt ctgttctcac tttttcataa acaacgattt ttccctcttc
     6901 atcaaagcgt aaaataggtt taatactcaa aagatttcca agaagagcag acccatttga
     6961 caggcgtccg cctttaacca gatgattaag gtcatcaacc ataataaagg ctgtcgtccc
     7021 atcaatctgt tcttgcagct tgtttaaaat agcttgaaat gtcattcctt gacgtgacca
     7081 atctagcaca ttttttacca tactacctaa aggagcagat gtgatcttac tgtctggaaa
     7141 tgccatttca atctcaggat gttcttcagc taaaaattga atattttgcc aaaagcctga
     7201 gattcctcca gctaagaaca agccaataac atgtgtataa cccttagaag acaaaagtcc
     7261 taaaagatta tctagttcag ataaacttgg ctgacttgtc ttgggaagat tttgggagtc
     7321 agccatcttt tgataaaaat catctatact caaatttcga ccttcaaaat aggtctcatc
     7381 gtcaatgata actggtatat caaggctaaa aatagcttta tcttgtttca gatctgttgg
     7441 tagtgttgct gtactgtcag taattactgc taatttcatt aatttttaaa ctccaaatga
     7501 atacctggac gatccaaggc aatttctgtg acttcataag tcaatcgctt aaccatgtct
     7561 agcaaaggag cagctaagga ttcaacttcc tcttgcgtaa attcgcttgg tttatccact
     7621 aaacgatcta aaatgcgaac catttgtgag atgaccccac taataacaaa ttcttctttg
     7681 acaataacaa attgcaatac agatacaatt actgtttctt tttgctgctc atctttatca
     7741 atcaactgaa aagtcacttc aaaattggtc tctggtgttc cgttttcttt ttcccactct
     7801 aaatttctag catcataatg gtactggttg acaaattctt tttcacgaac taattgcatt
     7861 ttttattctc cttggtatca atatgatcca ttatagcata gatttgaaga ttattaaagt
     7921 agcccctaaa ctactatttt cgcataacgt tttaaacagt gctatctctc gaacagatat
     7981 ctattttttc acctatttat atttagtcgt tcttatactg acattatatc aaaaaaacac
     8041 ccgttagtgg tcttgtactg cacctcaatt aaaacagaaa cactggtcag gtaagtttta
     8101 agtccaggat aaaaaggttt atcaccaagg cctcatcatg cttagccaag tatttcgaac
     8161 tagcttgtct tagctctagt cgctcaaacg taaatcctag gcgttcaatc cgtcgcaaaa
     8221 cctctccaac taacccatac ttaaacccat agggcttaat catcgctccg cccttcttct
     8281 ccttttatcc attataaaat aaaaacgttt taacagacaa aaaataggaa agtaccagac
     8341 tattggattt atttttttat ctcaaactcc attaacgatg ttgagttaaa ggcattcaaa
     8401 acaacataga tcgtaaacta acaagatttt ttatcaattg aacctatcgt ccccagttat
     8461 acacgacctc ttctggatga ggtctttttt tatttgtcta atttcatcaa cgcttcttcc
     8521 cctctttctt ctatcacaac tctcctattg ctcacttcct catgcggcaa catatcatca
     8581 aaaaaccgtc cattttaagc acaaccacta ctgtatctct tgtgatatct ccattgtcaa
     8641 tcgcttgttt aagtttatta aaaattattt aaaaaattaa atattatttt aaaaacttgc
     8701 aataatatat gtctatatta tataatttat ttataataaa attatataga aaaaggtact
     8761 cttatgagaa aaagatgcta ttcaacttca gctgcagtat tggcagcagt gactttattt
     8821 gctctatcgg tagatcgtgg tgttatagca gatagttttt ctgctaatca agagattaga
     8881 tattcggaag taacacctta tcacgttact tccgtttgga ccaaaggagt tattcctcca
     8941 gcaaaattca ctcaaggcga agatgttttt cacactcctt atgttgctaa ccaaggatgg
     9001 tatgatatta ccaaaacatt caatggaaaa gacgatcttc tttgcggggc tgccacagca
     9061 gggaatatgc ttcactggtg gttcgatcaa aacaaagaaa aaattgaagc atatctaaaa
     9121 aaacacccag ataaacaaaa aatcatgttt ggtgatcaag aattattgga tgtaagaaaa
     9181 gttattaata ctaaaggtga ccaaacaaat agcgagcttt ttaattattt ccgagataaa
     9241 gctttccccg gtttgtcagc acgccgaatt ggagttatgc ctgatcttgt tttagatatg
     9301 tttatcaatg gctattactt aaatgtttat aagacacaga ctactgatgt caatagaacc
     9361 tatcaagaga aagatcgccg aggtggtatt tttgacgccg tatttacaag aggtgatcaa
     9421 agtaagctat tgacaagtcg tcatgatttt aaagaaaaaa ctctcaaaga aatcagtgat
     9481 ctcattaaga aagagttaac cgaaggcaag gctctaggcc tatcacacac ctacgctaac
     9541 gtacgcatca accatgttat aaacctgtgg ggagctgact ttgattctaa cgggaacctt
     9601 aaagctattt atgtaacaga ctctgatagt aatgcatcta ttggtatgaa gaaatacttt
     9661 gttggtgtta attccgctgg aaaagtagct atttctgcta aagaaataaa agaagataat
     9721 attggtgctc aagtactagg gttatttaca ctttcaacag ggcaagatag ttggaatcag
     9781 accaattaaa gcgtatcaat aagaaaaatt acatttaata ataactataa tttagtatac
     9841 tgattaagtt aatgaattaa gatattagga gaaaaaatgg aaaaaaagtt ttgacgttgt
     9901 tcattcttat gtgctcatca attattttat atactactaa gggtatcttt tcaaatacgt
     9961 atattacg
//
LOCUS       DATTYN010000041         9697 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.41, whole genome shotgun sequence.
ACCESSION   DATTYN010000041 DATTYN010000000
VERSION     DATTYN010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9697
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.41"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            132..665
                     /locus_tag="VB649_001683"
     CDS             132..665
                     /locus_tag="VB649_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670615.1"
                     /translation="MKKTILTSLTLFSTLLLVACSSDKVTKSKTEINSDKSTKTVEKP
                     KNKVDNSKYDSVVSKLNNELNQDNSTKMESKIENNVVEGDYPNGHTVIRLLVKDDAKK
                     MFSEMLNAEDANTATADQKNALNMLRMSISQIAKELPDDTTTIDFGYEMSADNYRLIA
                     KSSKIKDIIPIGDLVME"
     gene            792..1934
                     /locus_tag="VB649_001684"
     CDS             792..1934
                     /locus_tag="VB649_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP1670616.1"
                     /translation="MWIEEQSNGKLRYVERYKEHYTGKYKRAYELIERDTPQGRKKAA
                     TALRLKIEKLVHIRPKKEKVTFGEVYQNFYSSWSLGVKQSTIYSTKNIDRIILKKIPN
                     DYLISKIDRRFLQKIFDDLLSEGRSHNYVKKVKWKLNRIFKYALRMDYIDVNEMIHVE
                     LPKEILTAEQAKKKKEKFLDQKEFKLFAQNLREEVYRDYRVKKYLRIAIVLYLTGMRY
                     GELAGLNISKDIDFKKKTIHIQHTFNFRTKQRTTPKTKGSDRIIEVSDTVLKNIQEQL
                     AENIRAGFETDYLFINTLGYPTTPERVIGAFKRHGQKAGIEKNITTHIFRHSHISLLA
                     EIGIPLPAIMERVGHSDSKTTLEVYSHVTLQMTTNLAKKLNEVKLF"
     gene            complement(2012..2110)
                     /gene="ffs"
                     /locus_tag="VB649_001685"
     ncRNA           complement(2012..2110)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VB649_001685"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            2310..3542
                     /locus_tag="VB649_001686"
     CDS             2310..3542
                     /locus_tag="VB649_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEP1670617.1"
                     /translation="MGVMMKQKIKILTVIGLMTVGMSACHNTSKPSNTDSVFSLTGKK
                     RQQIVKQVRQRYYFQQLSKTEQENYLTLYDSLAQFREIISLTPASKKSLIKTIDAFVM
                     DNPEFYWITSADYRFEFSDQTVFVTFPIPEDAKNVYQDLQAIGNDIVANTPSKDRYEQ
                     VKYFYEVIIRDTDYNKKAFEAYQSGSQAQVASNQDIKSVFIDHLSVCNGYAQAFQFLC
                     QKAGIPVAYIRGTGTSQQPQQSFAHAWNAVQINNTYYGVDVTWGDPVFDNHLSHQKQG
                     TINYSFLCLPDYLMALSHQPSKDIAFNTKERFENVWTIPSCTDDSLLYSKRHQSYIST
                     FDSDAILASLENQLLNRQEQLSLQFAHQDDYQQMVTDLTTNQTGYHNLFNQYWNNYTG
                     FTYGLLPETLSISFASRN"
     gene            complement(4152..4667)
                     /locus_tag="VB649_001687"
     CDS             complement(4152..4667)
                     /locus_tag="VB649_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEP1670618.1"
                     /translation="MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRG
                     HNAREESNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     IYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
                     HLIKEQSDPFD"
     gene            complement(4667..5446)
                     /locus_tag="VB649_001688"
     CDS             complement(4667..5446)
                     /locus_tag="VB649_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEP1670619.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTSYLVTGPDGFQLLMDAGSRALNEL
                     EKEISPLDLDAVIISHYHPDHVADLGVLRHYFQLYPKHLWQPKVLPIYGHDEDRHEFA
                     KLSIPDVSEGRAYDVTGVERIGPFDITFLKTVHPVVCYASRIVERATGQVLVFTGDSG
                     YFEGLADFAKEADLFLADVYLYEGNENHMAHLTSKEAGLMASQAGVKKLVLTHMPPVP
                     PDGINSKNHLEVLRQETQVYAGNIPVDLALPHKSWNLGSLS"
     gene            complement(5586..6125)
                     /locus_tag="VB649_001689"
     CDS             complement(5586..6125)
                     /locus_tag="VB649_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEP1670620.1"
                     /translation="MFTTKELVKVAMMTTLIIILGFIPAIPLGFIPVPIVLQNLGVML
                     AGLMLGGKKGTLSVFLFLVIGLFLPVFSGSRTTIPVLMGPSAGYVIAYLLVPIVFSLL
                     YRNWFSKSTPLAFLALLISGVVLVDVLGAIWLAAYTGMSLVTSLLSNLVFIPGDTIKA
                     IIATIIAVKYKDSFLNTKQ"
     gene            complement(6129..6440)
                     /locus_tag="VB649_001690"
     CDS             complement(6129..6440)
                     /locus_tag="VB649_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670621.1"
                     /translation="MTDCFGIDLDQEYRCLHYHTPLDIVGLKCAFCQTYYACYHCHDQ
                     LTDHAFVPTGHQETSPVICGHCRKLLSLAEYGCGCCPYCQSPFNPACHRHKDIYFLKE
                     S"
     gene            complement(6657..7799)
                     /gene="tgt"
                     /locus_tag="VB649_001691"
     CDS             complement(6657..7799)
                     /gene="tgt"
                     /locus_tag="VB649_001691"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEP1670622.1"
                     /translation="MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSI
                     GGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIR
                     LTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF"
     gene            8017..8880
                     /locus_tag="VB649_001692"
     CDS             8017..8880
                     /locus_tag="VB649_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEP1670623.1"
                     /translation="MSIKAIKGQARDTLKNLSGKYLLFLIPTLLFMFHFGIEIHQGYV
                     LSSGIEVSLAASYFPLLLGLILSLFILSASFTMIDVVRHFRQKVSFAESTTAFSKEFF
                     GNLLVLAITKWLFFLIWSLIWFFGLFIFLSGLSAFLVNAKSGGSTVISLIFLLFGAVL
                     SLIGFGIYINRYYAYSLSEYLLYDEVKEGTYLGAIAVIETSVAMMKGYKWKLFFLQLS
                     FTGWFLLNIVTFGLLNIYLLPYFTTANVIFYDQLKKRFKDKDDPIEGEHLSLHQLNKK
                     PTPMMYDDQKD"
     gene            9077..9697
                     /locus_tag="VB649_001693"
                     /pseudo
     CDS             9077..9697
                     /locus_tag="VB649_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3179 a         1907 c         1762 g         2849 t
ORIGIN      
        1 ttatctttat gggatgactt agaaaatttt aattacactc attttatgga aaagtacgaa
       61 ctgacctcgc ttgctgacga gtctatggtt attgaagaat tttataattt agttggataa
      121 aggggattta tatgaagaaa acaattttaa catcacttac tctattttca accctcttac
      181 ttgttgcctg ttcatctgat aaagttacta aaagtaaaac tgaaatcaat agtgataaat
      241 ctactaaaac agttgaaaaa cctaaaaata aagtggataa tagcaaatac gattccgttg
      301 tgagtaaact taacaatgaa ttaaatcaag ataattcaac taaaatggaa tcaaagattg
      361 aaaataacgt tgttgaaggc gactatccga atggtcatac tgtaattaga ctactcgtaa
      421 aagatgatgc caaaaaaatg ttttctgaaa tgttaaatgc tgaagatgct aatacggcta
      481 ccgctgatca gaaaaatgcc cttaatatgc taagaatgtc tatctcacaa attgcgaaag
      541 aattaccaga tgatacaaca actattgatt ttggatatga aatgtcagca gataattacc
      601 gcttaattgc aaaatcttca aaaattaaag atattatacc tattggtgat ttagttatgg
      661 aataaaataa aaaagcccta cgctcaaatt ttggtcgagg agagcgcaag gcgaatcatg
      721 tatagtaaaa acctgctttg cagtaggtct ctttactgta cccattttaa caggaaatga
      781 ggtaaaaatc aatgtggata gaagaacaaa gtaatggaaa attgcgatat gtagagcgtt
      841 acaaagagca ttatacagga aaatataaaa gagcctatga acttatcgaa agagatacac
      901 cgcagggaag aaaaaaagct gctacggctc tacgattgaa aatagaaaaa ctggttcata
      961 tcagacccaa aaaagaaaaa gttacctttg gagaggtcta tcaaaacttt tatagttcat
     1021 ggtcattagg tgtcaaacaa tccaccattt attctactaa aaatattgat aggataattc
     1081 ttaagaaaat tccgaatgac tatctcatta gtaaaattga ccgccgattt ttacagaaaa
     1141 tatttgacga tcttttgtca gaaggacgct cacataacta cgttaaaaag gtaaaatgga
     1201 aattgaaccg aatcttcaag tacgctcttc gtatggacta catcgatgtt aatgagatga
     1261 tccatgttga actaccaaaa gaaattctga cggctgaaca agcaaagaaa aagaaagaaa
     1321 aattcctaga tcagaaagaa tttaaactat tcgctcaaaa tttacgagag gaagtttata
     1381 gagattatcg tgttaagaag tatttacgta ttgctattgt actttattta acaggtatgc
     1441 gttatggtga gcttgctgga ttaaatatat ccaaagacat agactttaag aaaaagacaa
     1501 ttcacattca acatacattt aatttccgta caaaacaaag aacaacacct aaaaccaaag
     1561 gttctgatag aatcattgag gtttctgaca ctgtcttgaa gaatatccaa gaacagttag
     1621 ctgaaaacat ccgagctggt tttgagacag actatctttt cattaatact cttggctatc
     1681 caacaactcc cgagcgtgtc ataggagcat ttaagcgcca cggacaaaaa gctgggattg
     1741 aaaaaaatat taccactcat atttttagac actcacatat ctcattacta gccgaaatcg
     1801 gtattcctct acctgctatt atggaacgtg taggtcactc tgattctaaa actacattag
     1861 aagtatatag ccatgttact ttacagatga caacgaatct agctaaaaaa ctcaacgaag
     1921 ttaaactttt ttaaagttgc ccctaatttg cccctatttc actaaaatac cacagataaa
     1981 ccctttgaaa gcttgatttc aaagggtttt ctaaatgtac aaaaaaagag cacacacccg
     2041 aaaatcgctt agggctgctg gattcctccc ctgacccact tcacgcacaa gtgttgctcc
     2101 gcctattatt atatcatatt acggacagtt tgcaagtttt ccaactaagt aaaatcactt
     2161 tcaagtgagc atagcttcat tttgggacaa gatggactga atacctagaa aaatcatgac
     2221 cctttccaaa cacgattttg ctttttgaaa atctttccct ctccccattc cagctattct
     2281 ctatgttata ataagattat tagattagaa tgggagttat gatgaaacaa aagattaaaa
     2341 tcttaacagt aattggcctt atgacagttg gtatgtctgc gtgtcacaac actagcaaac
     2401 cttctaatac cgattctgtt ttttctttaa ccggaaaaaa gcgccaacaa atcgtcaaac
     2461 aagtaagaca acggtattat ttccaacaat tatccaaaac cgaacaagaa aattacctca
     2521 ctttatacga tagtctagca caatttcgtg aaatcatcag tttgacgccg gcttctaaaa
     2581 aaagcttaat taaaacgatt gacgcctttg tgatggataa tcccgaattt tactggatta
     2641 catctgccga ttatcgattt gagttttctg atcaaacggt ctttgtcacc tttcctatcc
     2701 cagaagatgc caagaacgtt tatcaagact tgcaagcaat cggtaatgat atcgtcgcaa
     2761 acacgccatc aaaggatcgc tatgagcagg tcaaatattt ttatgaggtc atcattcgag
     2821 acacagacta caataaaaaa gcctttgaag cctatcaatc aggcagtcaa gcccaggtcg
     2881 cttctaatca agacattaaa agtgttttta ttgatcattt atctgtttgt aatggctatg
     2941 cccaagcctt tcagtttctt tgtcaaaaag ctggcattcc agtcgcctat atccgtggaa
     3001 ctggtacatc tcagcaacct cagcaatctt ttgcacatgc atggaatgct gttcaaatta
     3061 ataacactta ttatggcgtt gatgtcactt ggggtgaccc tgtttttgat aaccatctct
     3121 cacatcaaaa gcaaggaact atcaattaca gttttctatg cctaccagat tatctaatgg
     3181 ccttatcaca tcagccaagc aaagacattg cttttaatac taaagaacgt tttgaaaatg
     3241 tttggactat accttcttgt acagatgatt ctttgcttta ttctaaacgt catcaaagct
     3301 atatctcaac gtttgacagt gacgccatcc ttgcaagcct tgaaaatcag ttgttaaata
     3361 gacaagagca actgtctcta caatttgctc atcaagatga ttatcaacag atggtaactg
     3421 atttaacgac gaatcaaaca ggttatcata accttttcaa tcagtattgg aataattata
     3481 cgggctttac ctatggactc ttaccagaga ctcttagtat ttcatttgct agtaggaact
     3541 aggtttagac acatgaaaca caaagttaag atgattatct ttgtcaaaca ttacaagaaa
     3601 ttgatatact aacacaattg aaggcgatta ttattctaac cgtcttcaat agatataacc
     3661 ttttcagatt gagcacatct aatgtaacat tagcaacagt gatgagctct tttttaatgc
     3721 tttagcaaaa tatatcagct aagacaaaag attaaataac tcaagccatg cctataagtc
     3781 acttgttttt aatccctgtg tcagtgtcaa tctacgccac agataactga cagctctgaa
     3841 ccttagaagt ctaagcttga taagtttact aaaaacaaaa ataaggtgag ccattactat
     3901 ctgtttttag atagtaaatc tttttaagaa tgactaactc atctagtcat cacgtgtttt
     3961 atttttcgat tgttttcacc tcgattgggt ctgaaaaaga gcgcttctag tacttggaaa
     4021 cgcccttttg tatattctat cttcgtatgt tgaatctaac aaccattgga aaaatggtct
     4081 aacgtttcac tcattatttt gacaggctac ccttcaccaa aaatgcatgt gataacaaac
     4141 tccttaaaac tctagtcaaa gggatctgac tgttccttga tcaaatgctt agctattttt
     4201 ttgcgctctc gcccttggcg gaaaaaggtt tgcatgatgt tagcacagtc tgctgctagc
     4261 aggcctcgtt caacttgcac gcggtggttt aagcgctcat ctgtcaaaat ctggtaaagg
     4321 ctgtctgctc caccaaattt ttgattgctg gctccataaa taacatgcgg aatccttgct
     4381 agcccaatgg caccactaca catcacacaa ggctcgatgg tcacaaagag tgtggtgtct
     4441 aataaacgcc agttgccttc atgagcgtta gcctcgttaa tagccatgat ttcagcgtgc
     4501 ataatggctt ggttactctc ttcacgcgca ttgtgcccac gaccaataat ctcaccatcc
     4561 ttgacaatga cacagccaat ggggatttca gctttctgta aggatttttc ggcttctttt
     4621 aaagcctctt gcatgaaata agtttgctct tctaaactat atggcatcaa gaaagactcc
     4681 ccaagttcca agatttgtgt ggtaaggcaa ggtcaacagg aatattacct gcatagacct
     4741 gtgtttcttg cctcaacact tctaaatggt ttttggaatt aataccatct ggaggaaccg
     4801 gtggcatgtg ggtcaagaca agcttcttaa cacctgcctg gctagccatt agtcctgctt
     4861 ccttactggt caaatgggcc atatgatttt cattgccttc gtataagtaa acatccgcta
     4921 agaaaaggtc tgcttctttt gcgaagtctg ccaatccttc aaaataacca ctgtctccag
     4981 taaagacaag tacctgacca gtcgctcttt ctacaattcg agaggcatag cacacaactg
     5041 gatgaaccgt tttaagaaag gtaatgtcaa aaggaccaat ccgttcaact ccagtgacat
     5101 cataggctct accttctgaa acatcaggaa tgcttaactt agcaaattcg tgtcggtcct
     5161 catcatgccc ataaatgggc aatactttag gctgccacag gtgtttagga taaagttgaa
     5221 aataatggcg caacacgcct aagtcggcta cgtgatcagg atggtagtgg ctaataatca
     5281 ctgcatccaa atcgagagga ctgatttctt tttccagctc attgagcgct cgactaccag
     5341 catccatcaa taactgaaag ccgtcaggtc ctgtgaccaa ataagaggtt gtgcctgcat
     5401 cttgataggg ataggctccc caagacccta aggtggttaa tttcatctca aacccttctt
     5461 tcttgcttta actcttatta taacaaaaat tagtgtcaaa gaggattgag acccaccaaa
     5521 aacaggtcct agcagataaa tctgccaaga cctgttcaac acaacttaac tatttgatga
     5581 ttagattact gttttgtatt caaaaaacta tctttgtatt taacagcgat aatggtcgca
     5641 atgattgctt tgatggtatc tcctggaata aagaccaagt ttgacaaaag cgatgtcaca
     5701 agagacatgc cagtgtaggc tgccaaccag atagcaccca gaacatcaac cagtacaact
     5761 cctgagatta aaagagctag gaatgccaat ggcgtgcttt ttgagaacca gttgcggtaa
     5821 agtaatgaaa agacaatagg cacaagaagg taggcaataa catagccagc agatggcccc
     5881 atcaatactg gaatggttgt tcttgagcct gagaaaacag gtaagaaaag gccaatcact
     5941 aaaaataaga aaacagataa ggttcccttt ttaccaccca gcatcaatcc agccaacatg
     6001 acacctaagt tttgtaaaac aatagggact gggataaagc ctagcgggat agcaggaata
     6061 aagcctaaaa taataatcaa agtggtcatc atagccacct taacaagttc tttggttgta
     6121 aacatctgtt acgactcctt taaaaaatag atatccttgt gcctatgaca ggctggatta
     6181 aagggacttt gacaataagg acagcatcca caaccatact cagctaggct caagagcttt
     6241 cgacaatgcc cacaaataac aggagatgtt tcttgatgtc ctgttggcac aaaggcatga
     6301 tctgttaact ggtcatggca atggtagcaa gcataataag tctgacaaaa agcacatttg
     6361 agcccaacaa tatcaagcgg ggtatgataa tgtaggcacc gatactcttg gtcaaggtca
     6421 attccaaaac agtccgtcat atctcatcct cttgtaacag tttaatcaaa agcatatgat
     6481 ttgtcaactc tatttttaca aaagggtaac tgttttctga aaaagaacac gtaaaacaag
     6541 aacttccctt taaagaggga cctatcagtt gaaagcaata ggacatccgt ctatacaaaa
     6601 aaactgaaac caaagacgat agatcgccct cagttccagg atcatagcat ttttaattag
     6661 aaattacggt ttgatttatt ataaccatac cgttcaagaa aatcttggcg gaattcaagt
     6721 aagttatcgt ccataatagc ctgacgtact tttttcatca agttaaccaa gaaataaagg
     6781 ttgtggtagc ttgtcaaacg aataccaaaa gtttcgtccg cttttagcaa gtgacgaatg
     6841 taggcacggc tatagttttg acaagtgtag cagtcacagt catgatcaag tggggtaaaa
     6901 tcttcagcga atttggcatt tttaaccaca agacgcccct cactagtcat acaagttccg
     6961 ttacgggcga tacgcgttgg caagacacag tcaaacatat ctacaccacg aatcacacca
     7021 tcaatcaagc tatctggtgc tcccactccc atcaggtaac gaggtttatt ttctggtaag
     7081 aggggagtcg taaagtcaag gacggcattc atttcttcat ggctctcccc aacagctaaa
     7141 ccaccaatag aataacctgg gaaatccata gccaccaaat ctgccgcaga ctgacgacga
     7201 aggtcctcaa atccagctcc ttgcacaatt ccaaataatc cttggtcatg aggacgacga
     7261 tgggctttta agccacgttc tgcccaacgg ctagtacgtt caatggattt tttcacgtaa
     7321 tcataaggtt ggtaaaattg cgggcactcg tcaaaactca tcatgatgtc tgagccaagg
     7381 ttattctgaa tggaaatggc tttttcgggt gatagaaaca tttttgagcc attcaagtga
     7441 tttttgaaag tcactccttc ttcagtgatg tttcgtgaat cggctaaaga gtaaacttga
     7501 aaaccacccg aatcggttaa gattggctga tcccagttca taaacttgtg cagaccacca
     7561 gagcgagcaa tcaactcatc tcctggacgc aaccagaggt gataagtgtt tgataaaata
     7621 atccctgatc caattgcttt taactcttct ggagactgtg ttttaacagt agcctgagtt
     7681 cccactggca taaacattgg tgtcggaaag gtcccgtgag gggtgataat ttcgcccaag
     7741 cgtgcaccgg tgtgcttttc tgttttgata aggcgatact taatcggata atctgtcatg
     7801 tgctttcttc cttgctatca agataaacag tcttgagctt ttttgatctg cctgagtttc
     7861 catcataatg aagggcttca agatgacatg ttgttctagc gcctatcatt ttatcaaaaa
     7921 atccataatt tgtcatgctt tcccaaaaag tatagtcaaa ataatggtta gctgtctcat
     7981 tttgttttat ggtataatga aataaaggag tctgttatgt caattaaagc aatcaaaggc
     8041 caggctagag acacgttaaa aaatctttct ggcaagtatt tactattttt aattccaacc
     8101 cttctcttta tgtttcattt cggtattgag attcatcaag gttacgtcct atctagtggt
     8161 attgaagtct cgctagcggc tagttatttc ccattactac taggacttat ccttagcctt
     8221 ttcattttat cagcatcctt tacgatgatt gatgttgtta ggcattttcg tcagaaagtt
     8281 tcttttgccg aatcaacaac agccttctca aaagaattct ttgggaacct gctggtttta
     8341 gcgatcacta agtggctatt ctttctcatc tggtcactaa tttggttttt tggcctcttt
     8401 attttccttt ccggactttc agcgtttttg gtcaatgcta aatcaggtgg ctcaacagtc
     8461 atttcactga tctttttact atttggagca gttttgtcct taattggttt tggtatttat
     8521 atcaaccgtt attacgctta tagtctatca gaataccttc tctacgatga ggttaaagag
     8581 gggacttatc taggagctat agccgtcatt gaaacaagtg tagctatgat gaaaggttat
     8641 aaatggaagc tttttttcct acaacttagc ttcaccggtt ggtttctact gaatattgtt
     8701 acttttgggt tacttaatat ctatctttta ccatatttta caacagccaa tgtcattttt
     8761 tatgatcaac tcaagaaacg tttcaaagac aaagatgacc caattgaagg agaacattta
     8821 agccttcatc agcttaataa aaagcctact cctatgatgt atgacgatca aaaagactaa
     8881 ataaatcctc catccataaa aatagccctt gaactgcacc ccaaaagtta gacacaaaat
     8941 ctaacgattg gggtgctatt tttttatgaa atttaatcaa gaaacgaaag ttaagattta
     9001 tgagttacgg caaatgggag agtccattaa atccatatca aaaaagtttg atatggcata
     9061 atccgatctc aaatatatga ttcgcttgat tgataggtat ggggtaacca ttgttcaaaa
     9121 atgtaagaat cattattatt ctctagaact gaagcaagag ataataaata aagttctgat
     9181 tgacggccaa tctcagaaac aaacatcctt agattatgct ttaccaactt ctagtatgct
     9241 ctcaaggtgg atagcgcaat acaagaaaaa cggttatact attcttgaaa aaccaaaagg
     9301 gaaaccgagt aagatggggc gtaaacgtaa gaaaaatttg gaagagatga cagaggttga
     9361 acgtcttcag aaggaattag aataccctag agcggagaat gctgtgctaa aaaagctgag
     9421 agaataccgc ttgagagacg aagcaaaact caaagagcaa cagaaatcat tcaagcatta
     9481 aggaatcaat ttccctagag atgctacttg aaatccttga tttaccgcgc tccacctatt
     9541 actatcaagt gaagcgacta gctcaaggag ataaagatat agaactaaag catgtgattc
     9601 gagagattta tgatgagcat aaaggtaatt acggttatcg tcgtattcat atggagttgc
     9661 gtaaccgagg atttgtggtc aatcataaga aagttca
//
LOCUS       DATTYN010000042         9636 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.42, whole genome shotgun sequence.
ACCESSION   DATTYN010000042 DATTYN010000000
VERSION     DATTYN010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9636
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.42"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            129..4235
                     /gene="cas9"
                     /locus_tag="VB649_001694"
     CDS             129..4235
                     /gene="cas9"
                     /locus_tag="VB649_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922251.1"
                     /note="Cas9, originally named Csn1, is the large,
                     multifunctional signature protein of type II CRISPR/Cas
                     systems. It is well known even to general audiences
                     because its RNA-guided endonuclease activity has made it a
                     popular tool for custom editing of eukaryotic genomes;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR RNA-guided endonuclease Cas9"
                     /protein_id="HEP1670624.1"
                     /translation="MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIK
                     KNLIGALLFDSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDDSFFHRLE
                     ESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKVDLRLIYLALAH
                     MIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASRVDAKAILSARLSK
                     SRRLENLIAQLPGEKRNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLD
                     NLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTL
                     LKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAK
                     LNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPY
                     YVGPLARSNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVL
                     PKHSLLYEYFTVYNELTKVKYVTEGMRKPAFLSGEQKKAVVDLLFKTNRKVTVKQLKE
                     DYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLT
                     LFEDKEMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKQSGKTILDF
                     LKSDGFANRNFMQLIHDDSLTFKEDIQKAQVSGQGDSLHEHIANLAGSPAIKKGILQT
                     VKVVDELVKVMGRHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSDILKE
                     YPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKV
                     LTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKA
                     GFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQF
                     YKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQEIG
                     KATAKYFFYSNIMNFFKTEITLANGEIRKRPLIETNGETGEIVWDKGRDFATVRKVLS
                     MPQVNIVKKTEVQTGGFSKESILPKRNSDKLIARKKGWDPKKYGGFDSPTVAYSVLVV
                     AKVEKGKAKKLKPVKELVGITIMERSSFEKDPIDFLEAKGYKEVRKDLIIKLPKYSLF
                     ELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYEKLKGSPEDNEQKQLFVEQH
                     KHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNLGA
                     PAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQLGGD"
     gene            4235..5104
                     /gene="cas1"
                     /locus_tag="VB649_001695"
     CDS             4235..5104
                     /gene="cas1"
                     /locus_tag="VB649_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CRISPR-associated endonuclease Cas1"
                     /protein_id="HEP1670625.1"
                     /translation="MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLE
                     TTDIVLSTMLVKRLVDENVLVIFCDDKRLPTAMLMPFYGRHDSSLQLGKQMSWSETVK
                     SQVWTTIIAQKILNQSCYLGACSYFEKSQSIMDLYHGLENFDPSNREGHAARIYFNTL
                     FGNDFSRDLEHPINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDI
                     MEPFSPLVDKIVYENRNQPFSKIKRELFTLFSDTFVYNGKEMYLTNIISDYTKKVVKA
                     LNNEGRGVPEFRI"
     gene            5101..5442
                     /gene="cas2"
                     /locus_tag="VB649_001696"
     CDS             5101..5442
                     /gene="cas2"
                     /locus_tag="VB649_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HEP1670626.1"
                     /translation="MSYRYMRMILMFDMPTDTDEERKAYRKFRKFLLSEGFIMHQFSI
                     YSKLLLNNTANNAMIGRLREHNPNKGNITLLTVTEKQFARMIYLHGERNNCIANSDER
                     LVFLGEAFDES"
     gene            5432..6094
                     /gene="csn2"
                     /locus_tag="VB649_001697"
     CDS             5432..6094
                     /gene="csn2"
                     /locus_tag="VB649_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II-A CRISPR-associated protein Csn2"
                     /protein_id="HEP1670627.1"
                     /translation="MNLNFSLLDEPIPLRGGTILVLEDVCVFSKIVQYCYQYEEDSEL
                     KFFDHKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVA
                     TITELIVFECLENELDLEYDEITILELIKCLGVKVETQSDTIFEKCLEILQIFKYLTK
                     KKLLIFVNSGAYLTKDEVASLQEYISLTNLTVLFLEPRELYDFPQYILDEDYFLITKN
                     MV"
     gene            6345..6751
                     /locus_tag="VB649_001698"
                     /pseudo
     CDS             6345..6751
                     /locus_tag="VB649_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480713.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
     gene            6875..8707
                     /gene="lepA"
                     /locus_tag="VB649_001699"
     CDS             6875..8707
                     /gene="lepA"
                     /locus_tag="VB649_001699"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEP1670628.1"
                     /translation="MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQ
                     VRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVAD
                     TRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDEDMIE
                     VSNPSEFPDPTRVAFIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYDMSEYRRSQLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDAKK"
     gene            8990..>9636
                     /locus_tag="VB649_001700"
     CDS             8990..>9636
                     /locus_tag="VB649_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEP1670629.1"
                     /translation="MLTFGGASAVKANQQQAIKETQERLLALREGFPDVKEIYKSNSV
                     NQTTPYYQYLEKLDKSLRSYLKELDENLHQLKGDQGEPGPRGEMGPAGPRGPVGPAGQ
                     DGQDGQNGAKGEVGPQGPRGAQGPTGPKGERGERGEAGPAGKDGEAGAQGPMGPAGPQ
                     GPRGDKGETGDKGDQGPAGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQDGKDGL"
BASE COUNT         3178 a         1558 c         2078 g         2822 t
ORIGIN      
        1 ttgaagagat gttttgaaaa agaaaaatta aagcatatta aactaatttc ggaggtcatt
       61 aaaactatta gtgaaatcat caaactcatt atggatttaa tttaaacttt ttattttagg
      121 agacaaaaat ggataagaaa tactcaatag gcttagatat cggcacaaat agcgtcggat
      181 gggcggtgat cactgatgat tataaggttc cgtctaaaaa gttcaaggtt ctgggaaata
      241 cagaccgcca cagtatcaaa aaaaatctta taggggctct tttatttgac agtggagaga
      301 cagcggaagc gactcgtctc aaacggacag ctcgtagaag gtatacacgt cggaagaatc
      361 gtatttgtta tctacaggag attttttcaa atgagatggc gaaagtagat gatagtttct
      421 ttcatcgact tgaagagtct tttttggtgg aagaagacaa gaagcatgaa cgtcatccta
      481 tttttggaaa tatagtagat gaagttgctt atcatgagaa atatccaact atctatcatc
      541 tgcgaaaaaa attggcagat tctactgata aagtggattt gcgcttaatc tatttggccc
      601 tagcgcatat gattaagttt cgtggtcatt ttttgattga gggagattta aatcctgata
      661 atagtgatgt ggacaaacta tttatccagt tggtacaaac ctacaatcaa ttatttgaag
      721 aaaaccctat taacgcaagt agagtagatg ctaaagcgat tctttctgca cgattgagta
      781 aatcaagacg attagaaaat ctcattgctc agctccccgg tgagaagaga aatggcttgt
      841 ttgggaatct cattgctttg tcattgggat tgacccctaa ttttaaatca aattttgatt
      901 tggcagaaga tgctaaatta cagctttcaa aagatactta cgatgatgat ttagataatt
      961 tattggcgca aattggagat caatatgctg atttgttttt ggcagctaag aatttatcag
     1021 atgctatttt actttcagat atcctaagag taaatagtga aataactaag gctcccctat
     1081 cagcttcaat gattaagcgc tacgatgaac atcatcaaga cttgactctt ttaaaagctt
     1141 tagttcgaca acaacttcca gaaaagtata aagaaatctt ttttgatcaa tcaaaaaacg
     1201 gatatgcagg ttatattgat gggggagcta gccaagaaga attttataaa tttatcaaac
     1261 caattttaga aaaaatggat ggtactgagg aattattggc gaaactaaat cgtgaagatt
     1321 tgctgcgcaa gcaacggacc tttgacaacg gctctattcc ccatcaaatt cacttgggtg
     1381 agctgcatgc tattttgaga agacaagaag acttttatcc atttttaaaa gacaatcgtg
     1441 agaagattga aaaaatcttg acttttcgaa ttccttatta tgttggtcca ttggcgcgta
     1501 gcaatagtcg ttttgcatgg atgactcgga agtctgaaga aacaattacc ccatggaatt
     1561 ttgaagaagt tgtcgataaa ggtgcttcag ctcaatcatt tattgaacgc atgacaaact
     1621 ttgataaaaa tcttccaaat gaaaaagtac taccaaaaca tagtttgctt tatgagtatt
     1681 ttacggttta taacgaattg acaaaggtca aatatgttac tgagggaatg cgaaaaccag
     1741 catttctttc aggtgaacag aagaaagccg ttgttgattt actcttcaaa acaaatcgaa
     1801 aagtaaccgt taagcaatta aaagaagatt atttcaaaaa aatagaatgt tttgatagtg
     1861 ttgaaatttc aggagttgaa gatagattta atgcttcatt aggcacctac catgatttgc
     1921 taaaaattat taaagataaa gattttttgg ataatgaaga aaatgaagat atcttagagg
     1981 atattgtttt aacattgacc ttatttgaag ataaggaaat gattgaggaa agacttaaaa
     2041 catatgctca cctctttgat gataaggtga tgaaacagct taaacgtcgc cgttatactg
     2101 gttggggacg tttgtctcga aaattgatta atggtattag ggataagcaa tctggcaaaa
     2161 caatattaga ttttttgaaa tcagatggtt ttgccaatcg caattttatg cagctgatcc
     2221 atgatgatag tttgacattt aaagaagaca ttcaaaaagc acaagtgtct ggacaaggcg
     2281 atagtttaca tgaacatatt gcaaatttag ctggtagccc tgctattaaa aaaggtattt
     2341 tacagactgt aaaagttgtt gatgaattgg tcaaagtaat ggggcggcat aagccagaaa
     2401 atatcgttat tgaaatggca cgtgaaaatc agacaactca aaagggccag aaaaattcgc
     2461 gtgagcgtat gaaacgtatt gaagaaggaa taaaagaact aggaagtgat attctaaagg
     2521 agtatcctgt tgaaaacact caattacaaa atgaaaagct ctatctctat tatctccaaa
     2581 atggaagaga catgtatgtg gaccaagaat tagatattaa tcgtttaagt gattatgatg
     2641 tcgatcacat tgttccacaa agtttcatta aagacgattc aatagacaat aaggtcttaa
     2701 cgcgttctga taaaaatcgt ggtaaatcgg ataacgttcc aagtgaagaa gtagtcaaaa
     2761 agatgaaaaa ctattggaga caacttctaa acgccaagtt aatcactcaa cgtaagtttg
     2821 ataatttaac gaaagctgaa cgtggaggtt tgagtgaact tgataaagct ggttttatca
     2881 aacgccaatt ggttgaaact cgccaaatca ctaagcatgt ggcacaaatt ttggatagtc
     2941 gcatgaatac taaatacgat gaaaatgata aacttattcg agaggttaaa gtgattacct
     3001 taaaatctaa attagtttct gacttccgaa aagatttcca attctataaa gtacgtgaga
     3061 ttaacaatta ccatcatgcc catgatgcgt atcttaatgc cgtcgttgga actgctttga
     3121 ttaagaaata tccaaaactt gaatcggagt ttgtctatgg tgattataaa gtttatgatg
     3181 ttcgtaaaat gattgctaag tctgagcagg aaataggcaa agcaaccgca aaatatttct
     3241 tttactctaa tatcatgaac ttcttcaaaa cagaaattac acttgcaaat ggagagattc
     3301 gcaaacgccc tctaatcgaa actaatgggg aaactggaga aattgtctgg gataaaggac
     3361 gagattttgc cacagtgcgc aaagtattgt ccatgcccca agtcaatatt gtcaagaaaa
     3421 cagaagtaca gacaggcgga ttctccaagg agtcaatttt accaaaaaga aattcggaca
     3481 agcttattgc tcgtaaaaaa ggctgggatc caaaaaaata tggtggtttt gatagtccaa
     3541 cggtagctta ttcagtccta gtggttgcta aggtggaaaa agggaaagca aaaaaactaa
     3601 aacccgttaa agagttggtt ggcatcacaa taatggaaag aagctctttt gaaaaagatc
     3661 cgattgactt tttagaagct aaaggatata aggaagttag aaaagactta atcattaaac
     3721 tacctaaata tagtcttttt gagttagaaa acggtcgtaa acggatgctg gctagtgccg
     3781 gagaattgca aaaaggaaat gagctagctc tgccaagcaa atatgtgaat tttttatatt
     3841 tagctagtca ttatgaaaag ttgaagggta gtccagaaga taacgaacaa aaacaattgt
     3901 ttgtggagca gcataagcat tatttagatg agattattga gcaaatcagt gaattttcta
     3961 agcgtgttat tttagcagat gccaatttag ataaagttct tagtgcatat aacaaacata
     4021 gagacaaacc aatacgtgaa caagcagaaa atattattca tttatttacg ttgacgaatc
     4081 ttggagctcc cgctgctttt aaatattttg atacaacaat tgatcgtaaa cgatatacgt
     4141 ctacaaaaga agttttagat gccactctta tccatcaatc catcactggt ctttatgaaa
     4201 cacgcattga tttgagtcag ctaggaggtg actgatggct ggttggcgta ctgttgtggt
     4261 aaatacccac tcgaaattat cctataagaa taatcatctg atttttaagg atgcctataa
     4321 aacggagctg atccatttat cagaaattga tattttgtta ttagaaacga ccgatattgt
     4381 cttgtccact atgctggtaa aacggctagt ggatgagaat gtccttgtca tattctgtga
     4441 tgataaacga ttaccaacag ctatgctgat gcctttttat ggtcgtcatg attcgagttt
     4501 acagcttggg aaacaaatgt cctggtcaga aacagtcaaa tcgcaggttt ggacgacgat
     4561 tattgctcaa aagattttga atcaatcttg ctatctagga gcatgctcct attttgaaaa
     4621 atcccaatct attatggatt tatatcatgg tttggaaaat tttgatccga gtaatcgaga
     4681 agggcatgca gcgagaattt attttaatac actttttggg aacgatttct caagagattt
     4741 ggagcatcca atcaatgcag gtctggatta tggttatact ttattattga gtatgtttgc
     4801 gcgtgaagtg gttgtgtctg gatgtatgac tcagtttgga ctcaaacacg ccaatcagtt
     4861 taatcagttc aattttgcta gcgatattat ggaaccattt agtcctttgg tggataagat
     4921 tgtttatgaa aatcgaaatc agccattttc caaaataaag agagagttat ttaccttgtt
     4981 ttcggacacc tttgtataca acggtaaaga gatgtatctc acgaatatta ttagcgatta
     5041 tactaaaaaa gttgtcaaag ctctgaataa tgaagggaga ggagttcctg aatttaggat
     5101 atgagttata gatatatgag gatgatactt atgtttgata tgccgacgga caccgatgag
     5161 gaacgaaaag cctatcgaaa atttcggaaa tttttactta gtgaagggtt tatcatgcat
     5221 caattttcta tttatagtaa gttgctgttg aataatacag ctaacaatgc catgattggt
     5281 cggctgaggg agcataatcc taataaagga aatattactt tattaacagt cacggaaaaa
     5341 cagtttgcac gaatgattta tttacatggt gaaagaaata attgtattgc aaactccgat
     5401 gaaagacttg tatttcttgg ggaggctttt gatgaatctt aatttttcct tactagatga
     5461 accgattcca ttaagaggcg gtacaattct tgtgctcgaa gatgtctgtg tattttcaaa
     5521 aatagtgcaa tattgttacc aatatgagga agattctgaa cttaaatttt ttgatcacaa
     5581 gatgaaaaca atcaaagaat cagaaatcat gcttgtaaca gatattttag gatttgatgt
     5641 taactcctca accattttaa aattgattca tgcagattta gaatctcaat ttaatgagaa
     5701 acccgaagtg aaatcgatga ttgacaaatt ggttgctacg attacagaac tgattgtctt
     5761 tgaatgctta gaaaatgaat tagatttaga gtatgatgaa attacaattc tggaattgat
     5821 taaatgttta ggagtaaaag tagaaacaca aagtgatact atttttgaaa aatgtctaga
     5881 aatacttcaa attttcaaat atctcactaa gaaaaagttg ctcatttttg tcaatagtgg
     5941 agcttatcta acaaaagatg aagtggctag tttacaagag tatatatcat tgacaaattt
     6001 aacagttctc tttttagaac cacgtgaact atatgatttt ccgcagtata ttttagatga
     6061 agattatttc ttaataacta aaaatatggt ataatactct taataaatgc agtaatacag
     6121 gggcttttca agactgaagt ctagctgaga caaatagtgc gattacgaaa ttttttagac
     6181 aaaaatagtc tacgaggttt tagagctatg ctgttttgaa tggtctccat tcaacattgc
     6241 cgatgataac ttgagaaaga gggttaatac cagcagtcgg atacctttct attctttctg
     6301 ttaaagcgtt ttcatgttat aataggtaaa agaagagtag agtgatggaa caaacatttt
     6361 ttatgattaa gccagatggg gttaagcgag ggggttagtt ggagaggttt tgcggcagat
     6421 tgaacgccta agacttacgt ttgagcgatt cgagctaaga caagctagtt cgaaatactt
     6481 ggctaagcac gacgaggcct tggtgataaa ccttttgatc ctaaacttaa agcttacatg
     6541 acaagtggtc ctgttttaat tgggacactt cttggggact aaggtggttt tgtctttttg
     6601 aaccatgatg agagtaacca atcctacgga tgctctttgc ggaaccattc gtgggaattt
     6661 tgctcaggct cctggtgatg atggaggtgt ttttaacatg gcgtatgggc ctcattcaag
     6721 agactctgct aggcgtgaga tcgctctttg atctcatcaa agtaatcatg gtagctccgc
     6781 tattctcttg caagataatc cgtaagaaaa gataggcaaa ggcctacctt ttttgttata
     6841 atagaaggaa agactaaatg tataggaaaa tagaatgaac agtcaagatt taaaaaaacg
     6901 tcaggagaag attcgtaatt tctccattat tgcacatatt gaccatggaa aatctactct
     6961 cgctgaccgc atcttggaaa agacagagac ggtttcgtct cgtgaaatgc aggctcagtt
     7021 attggactcc atggatttgg agcgcgagcg tgggatcacc atcaagttaa acgccattga
     7081 gcttaattac acggctaaag atggggaaac ctacattttc caccttattg ataccccagg
     7141 gcatgtggac tttacttatg aagtatcgcg ttcgttggca gcctgtgagg gagcgattct
     7201 agttgtggat gcagcgcagg gcattgaagc gcagacattg gctaatgttt acctagccct
     7261 cgacaatgat ttggaaattt tacctgttat caataaaatt gacttgcctg ctgctgaccc
     7321 tgagagagtc cgccatgaag tagaagatgt gattgggctt gatgcttctg aggctgttct
     7381 ggcgtcagcc aaggctggta tcgggatcga agagattctt gagcaaattg ttgagaaggt
     7441 tcctgctcct acgggtgatg tggatgcgcc tttacaagcc ttgatttttg actctgttta
     7501 cgatgcttat cgaggcgtta tcctgcaagt tcggattgtg aatggtattg tcaagcctgg
     7561 cgataaaatc cagatgatgt cgaatggaaa aacctttgat gttacagaag ttgggatttt
     7621 cactcctaag gcagttggac gagatttcct tgcgacggga gatgttggtt atgttgcggc
     7681 ctctatcaaa acggtagcag atacccgtgt gggggatacg gtgactttag ctaataaccc
     7741 tgctaaggaa gccttgcatg gctacaagca gatgaacccg atggtctttg cagggattta
     7801 tccgattgaa tcaaataaat acaatgactt gcgtgaagcg cttgaaaaat tacaactgaa
     7861 cgatgccagt ttacagtttg aacccgaaac gtcacaagcg cttggctttg gttttcgatg
     7921 cggtttttta ggcttgcttc acatggatgt gattcaagaa cgtttggaac gtgaatttaa
     7981 cattgatttg atcatgacag caccgtccgt ggtgtatcac gttcacacaa cagatgagga
     8041 catgattgaa gtgtctaacc cttcagaatt tccagaccca acccgtgtgg cttttattga
     8101 agagccttat gttaaagcgc aaatcatggt gccacaagag ttcgtagggg ctgttatgga
     8161 attatcgcag cgcaagcgtg gtgattttgt gaccatggat tacattgatg ataaccgtgt
     8221 caatgtgatt taccaaatcc cgctggctga aattgtcttt gatttctttg ataaattgaa
     8281 atcctcaacg cgaggttatg cgagttttga ttatgacatg tcagaatatc gcaggtcaca
     8341 attggtgaaa atggacattc ttttgaacgg tgataaggtc gatgcgctca gctttattgt
     8401 tcataaagaa tttgcttatg aacgcgggaa aattattgtt gaaaaattga aaaaaatcat
     8461 tccacgtcaa cagtttgaag tgccgatcca agccgctatt ggtcaaaaaa ttgttgcgcg
     8521 ttcagacatc aaggcccttc gtaaaaacgt tttagcgaag tgttatggcg gtgacgtgtc
     8581 tcgtaaacgt aaattgctcg aaaaacaaaa ggctggtaaa aaacggatga aggctattgg
     8641 ttctgtcgaa gtccctcaag aagccttctt gagtgttctt tcaatggatg atgatgccaa
     8701 gaaataacca agcttaaccg cttagtcttc agaggagaac tcttgtgggt ctgcatgacc
     8761 aaaaaattga ttatctcata aaaaaagaac tttacaatct ctttcacata acactataat
     8821 ggtattatag tgttatctca ttattaggtg agcctgcatt taatcttatt aaagagaaag
     8881 aggaaacaaa aactgtgaac aaaacaaaac aaaacaaaac aaaacaaaac aaaacaaaac
     8941 aaaacatagc cttctttgtc gctatggctt aacctcagcg gctgctcttt tgctgacctt
     9001 tggaggtgca agtgcagtta aggcgaatca acagcaagct atcaaagaga cacaggaacg
     9061 ccttttagca cttcgggaag gctttccaga tgtaaaagaa atttacaaga gtaatagtgt
     9121 taatcaaact accccgtatt atcaatattt agagaaactt gataaaagtt taagaagcta
     9181 tcttaaagaa ttagatgaaa acttgcacca gcttaaaggt gaccaaggag aaccaggtcc
     9241 acgaggcgaa atgggtcccg ctggtccacg aggtccagta ggtcctgctg gtcaagatgg
     9301 tcaggacggt caaaacggtg ccaaaggtga agtaggtccg caaggtccac gtggtgccca
     9361 aggccccact ggtccaaaag gagaacgtgg tgagcgaggc gaagccggtc ccgccggaaa
     9421 agatggtgag gctggagccc agggtccaat gggtcccgct ggcccacagg gtccacgtgg
     9481 tgacaagggc gaaactggtg acaaaggaga tcaaggtccc gccggaaaag atggtgaacg
     9541 tggtccagta ggtccagctg gcaaggacgg ccaaaacggc aaagatggcc tcccaggtaa
     9601 agacggcaag gacggccaag acggtaaaga tggtct
//
LOCUS       DATTYN010000043         9091 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.43, whole genome shotgun sequence.
ACCESSION   DATTYN010000043 DATTYN010000000
VERSION     DATTYN010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9091
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.43"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            69..142
                     /locus_tag="VB649_001701"
     tRNA            69..142
                     /locus_tag="VB649_001701"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:103..105,aa:Asn,seq:gtt)
     gene            complement(639..3215)
                     /locus_tag="VB649_001702"
     CDS             complement(639..3215)
                     /locus_tag="VB649_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEP1670630.1"
                     /translation="MKNNNKWIIAGLASFLFPLSIIFIILLSMGIYYNSDKTILASDA
                     FHQYVIFAQNFRNIMHGSDSFFYTFTSGLGINFYALMCYYLGSFFSPLLFFFNLTSMP
                     DAIYLFTLIKFGLIGLAACYSFHRLYPKISAFLMISISVFYSLMSFLTSQMELNSWLD
                     VFILLPLVVLGLNKLITENKTRTYYLSISLLFIQNYYFGYMIALFCILYALVCLLSLN
                     DFNKMFIAFVRFTAVSICAALTSALVILPTYLDLSTYGENLSPVKQLVTNNAWFLDIP
                     AKLSIGVYDTTKFNALPMIYVGLFPLMLSVIYFTLESIPLKIKLANACLLTFIIISFY
                     LQPLDLFWQGMHSPNMFLHRYAWSFSIVILLLACETLSRLKEVTQIKAGFAFIFLIIL
                     TSLPYSFSQQYNFLPLTLFLLSVFLLLGYTISLFSFRNSQIPSTFISAFILIFSLLES
                     GLNTYYQLQGINKEWGFPSRQIYNSQLKDINNLVNSVSKNSQPFFRMERLLPQTGNDS
                     MKFNYYGISQFSSVRNRLSSSLLDRLGFQSKGTNLNLRYQNNTIIMDSLLGIKYNLSE
                     GPLNKFGFTKLKTSGNTTLYQNHYSSPLAILTRNVYKDVNLNVNTLDNQTKLLNQLSG
                     KSLTYFNLQPAQLISGANQFNGQISAQASDYQNSVTLNYQINIPKHSQLYVSIPNIIF
                     SNPDAKEVRIQTDNHNFIYTTDNAYSFFDLGYFADAKVATFSFVFPKNKQISFKEPHF
                     YSLSIESYLEAMNSIKQKNVHTYAKSNTVITDYNSKTKGSLIFTLPYDKGWSAQKDGK
                     NLPVKKAQGGFLSVTIPKGKGRVILTFIPNGFKLGLSLSCVGIIAYMLLYKYIDIKSK
                     LL"
     gene            complement(3298..4917)
                     /locus_tag="VB649_001703"
     CDS             complement(3298..4917)
                     /locus_tag="VB649_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP1670631.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYNIMKEKDAI
                     YMKADFSEEDGVRAAELEGIFAELGGWEAESEASQLLQNLNIPEDLHYQNMSELANGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREMGNDFLTVENLSVTIDGEKI
                     IDNISFILRPGDKAAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSK
                     DFATEESILEWLRQFASKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLILDDPTNHLDLESISSLNDGIKDFKESVIFASHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLDNPEVQARVAELWK"
     gene            complement(4996..5868)
                     /locus_tag="VB649_001704"
     CDS             complement(4996..5868)
                     /locus_tag="VB649_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEP1670632.1"
                     /translation="MKKRGIDLLLVTIGSFITAIGFNTMFVDNHIASGGMVGIAVVIK
                     ALFGISPSLFLMASNIPLLLMCYFFLGKQNFIKTLYGSWIYPIAIRSTNSLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLFVIGYVISVMENGFDSSKNVMIISKDYQAIREYITTVMDRGV
                     TKLPIRGGYTTSDKIMLMAIVSSHELPTLQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KQYKREDKDVLLPM"
     misc_binding    5991..6232
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6287..7309
                     /gene="trpS"
                     /locus_tag="VB649_001705"
     CDS             6287..7309
                     /gene="trpS"
                     /locus_tag="VB649_001705"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEP1670633.1"
                     /translation="MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNQNKYKMFVFLA
                     DQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIE
                     QTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRERRLEYAKDMGEVFHMLQEGSQKARTVAAKTLSEVKSA
                     MGINYF"
     gene            7587..9068
                     /gene="guaB"
                     /locus_tag="VB649_001706"
     CDS             7587..9068
                     /gene="guaB"
                     /locus_tag="VB649_001706"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEP1670634.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTL
                     NIPIITAAMDTVTGSKMAIAIARAGGLGVIHKNMSITEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNR
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGDIQELHENAQFVEMSGAGLIESHPHDVQITNEAPNYSVH"
BASE COUNT         3047 a         1470 c         1716 g         2858 t
ORIGIN      
        1 cggcggtaac acgggttcga atcccgtacg gactatcgca attgtcattt tggcaatttt
       61 tttctttttc cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta
      121 ggttcgagtc ctactgccgg agtgataaga tatttcctaa gataatctta ggattttttt
      181 atttagtaaa acagatactc aggtcaaata ctcaatttac taattattaa accactaaat
      241 acagcattgt gaactaacag gattgtattt tgcattaaaa tagaagttct gttctttaat
      301 tgtatagatg ataacattaa gtttaattac aaacattaac tgaagcttaa ttttttacat
      361 tttgaaagca tgtctcccat ttaatactga tgaatataag attattgtaa ggagtcaaaa
      421 gattgaaatc gtatcagcga tgattattgt catttcaatc tttgaaagag agtagtttaa
      481 cattaaccct cacgaaaaat ctgaccttta tattatttga gtttattagt aaaatcgata
      541 aaagcatctc aagtattaga atatttgtct agctcttgag atgcttttag tatattgact
      601 catttgccaa attgataaaa aaatctgatt tttttggact aaagtaattt agactttata
      661 tctatgtact tatacaaaag catataagcg ataattccta cgcaagatag agataaccct
      721 aatttaaaac cattaggaat aaaggtaagg ataacacgtc cctttccttt aggaatagta
      781 actgatagaa atcctccttg tgcttttttg actggaagat ttttcccatc tttttgtgct
      841 gaccaacctt tatcgtaagg aagtgtaaaa ataagagaac ctttcgtttt tgaattataa
      901 tcagtgatta ccgtattact tttagcgtaa gtatgaacat ttttttgttt aatactattc
      961 attgcttcaa ggtaagattc aatagacaaa ctataaaaat gaggttcctt aaaactaatt
     1021 tgtttatttt ttggaaaaac aaacgaaaat gtagcaactt tggcatcggc gaaatatcct
     1081 aaatcaaaaa aagagtaagc gttatctgta gtatatatga aattatgatt atctgtctga
     1141 atacgcacct ctttagcatc aggatttgaa aatataatat tgggtatgct aacatagagc
     1201 tgactatgtt tagggatgtt aatttgataa ttaagggtaa cggagttttg ataatcagaa
     1261 gcttgtgcag atatttgtcc gttaaattga ttagcaccag aaataagttg agctggctgt
     1321 aagttaaaat aggttaaaga tttcccactt agttggttaa gtaatttggt ttggttatca
     1381 agggtattga catttaggtt gacatctttg taaacattac gtgttaatat agctaaaggg
     1441 ctactatagt gattttgata aagagtagta ttcccgctag tttttagttt tgtaaatcca
     1501 aatttattta gaggtccttc gctaagatta tattttatac caagtagact gtccataata
     1561 atagtattgt tttggtatct aaggtttaaa tttgtgcctt tagactgaaa tcccaatcga
     1621 tccaataaag aactagatag tctatttctt acagaggaaa attgtgaaat gccgtaataa
     1681 ttaaatttca tgctatcgtt ccctgtttgg ggaagtagcc tttccattct aaaaaaaggt
     1741 tgactatttt ttgacacaga gttgacgagg ttgttaatat cctttaattg actattatat
     1801 atctgtcgtg atgggaatcc ccactcctta ttaattcctt gaagctggta gtaggtgttt
     1861 aaccctgatt caagaaggct aaagataagt atgaaagcag aaataaaagt agatgggatt
     1921 tgagaatttc taaacgaaaa tagtgaaata gtataaccta ataataaaaa aacactaagt
     1981 aaaaaaagag ttaaaggtag aaaattatat tgttgagaaa agctataagg aagagatgtc
     2041 agtataatga ggaaaataaa agcaaaacct gcttttattt gagtcacttc ttttagtcga
     2101 gagagagtct cacatgcgag taataggata actatggaaa aagaccaagc gtagcgatgc
     2161 aaaaacatat ttggtgagtg catcccctgc caaaaaagat caagtggctg taggtaaaaa
     2221 cttattataa taaaagttaa caagcaggca ttggctaatt ttatttttaa agggatactt
     2281 tctaaagtaa aataaataac actaagcatt aggggaaata atcctacgta aatcataggc
     2341 agagcattaa acttggtagt atcgtacact cctattgaga gcttagcagg tatatccaaa
     2401 aaccaagcat tgttcgtaac taactgtttt accggggata gattctctcc ataagttgac
     2461 aaatctagat aggtaggaag tattactaga gcacttgtta aagcagcaca tattgacaca
     2521 gctgtaaacc taacaaaagc gataaacatt ttgttaaaat cattgagact taaaagacaa
     2581 actaaggcgt aaagaataca aaaaagagca atcatgtagc caaagtagta attttgaatg
     2641 aataataatg atatcgaaag ataataagtt ctggttttat tttctgtgat aagtttattt
     2701 aatccaagta caacaagtgg aagaagaatg aaaacatcta accaagaatt tagttccatt
     2761 tgacttgtca agaagctcat taagctataa aaaactgaga tggaaatcat caagaaagca
     2821 ctgatttttg gatataatct atgaaaagaa tagcatgcag ctaatcctat taacccaaat
     2881 tttatcaagg taaacaaata gatagcatct ggcatagagg ttaaattaaa aaagaaaagt
     2941 aatggagaaa agaaactgcc aagataataa cacattaaag cataaaaatt tatccctagt
     3001 ccgcttgtaa aggtataaaa aaaactatca gaaccatgca tgatgttacg aaagttctgc
     3061 gcaaaaataa catactgatg aaaagcatca ctagctagaa ttgttttatc actattataa
     3121 taaatgccca tcgatagaag gatgataaat ataatactaa gagggaacaa aaaactagca
     3181 agtccagcaa ttatccattt attattattt ttcataaatt atatggtctt tcgtttacaa
     3241 attttaaaaa agaggctagg aagagatctt cttagccacc tcatttatca taaggtttta
     3301 tttccaaagt tcagcaactc gggcttggac ttctggattg tcaaggaatt cgtcataagt
     3361 ttcatctata cggtcgataa caccattttt tgaaataaca acgatgtggt tagcaatcgt
     3421 ttgaataaat tcatggtcat gactggcaaa gataacagat tctttgaagt ctttgattcc
     3481 atcattaaga cttgaaatag attccaaatc taagtgatta gttgggtcat caagaataag
     3541 aacgtttgat ttcaatagca tcaacttaga aagcatgaca cgcacttttt cgccaccgga
     3601 aagaacgtta acagattttt taacttcgtc tccagagaaa agcatccgtc ctaagaaccc
     3661 acgtaaaaag gtatcatcat cttcaccttt tgaggcaaat tgacgtaacc attcaagaat
     3721 agattcttcc gtggcaaaat cttttgaatt gtctttaggc aagtaagaac gacttgttgt
     3781 cactccccat ttaatggttc cttcgtagtc aatatcatct gctaaagcac gcataagagc
     3841 ggttgtttga atatcatttt gaccaataat agcagctttg tcacctggac gtaaaatgaa
     3901 actgatatta tcaatgattt tctctccatc gatcgttaca gaaagatttt caacagtgag
     3961 gaagtcattc cccatttcac gctctgcttt aaaattaata aatgggtatt tacggcttga
     4021 gggaacaatt tcttctaatt caatcttatc aagcattttt ttacgagagg ttgcttgttt
     4081 tgatttagat gcgtttgctg agaaacgggc aacgaattct tgtagttctt tgattttttc
     4141 ttcggcttta gcattgcggt cagcttgtaa acgagcggcc agctcagaag attgtttcca
     4201 gaaatcgtag ttacccacaa agagtttgat tttaccaaag tcaaggtcgg ccatgtgagt
     4261 acatacttta ttcaagaagt gacggtcatg ggaaacaacg atgactgtat tttcaaaatc
     4321 aatcaagaaa tcttccaacc atgaaataga ttgaatatca agaccattgg ttggctcgtc
     4381 aagtaataaa acgtcaggct taccaaagag cgctttagca agaaggactt tcactttatc
     4441 tccattagcc agttcactca tattttggta gtgaaggtct tctggaatat ttagattttg
     4501 gagaagttga gaagcttcac tttctgcctc ccagccacct aattcagcaa agataccttc
     4561 tagctcagca gcacgaacac catcttcttc tgaaaagtca gctttcatat agatagcgtc
     4621 tttttctttc atgatattgt agagttgttc attacccatg attacaacat caatcgcacg
     4681 ttcttcttca taatcaaaat gattttggcg aagaacagat aagcgttcgt caggacctaa
     4741 agagatatga ccagtacttg gttcaatatc tccagcaagg attttaagaa aagttgattt
     4801 tccggcacca ttcgcaccga ttaagccgta agtattgccg gctgtgaatt tgatattaac
     4861 atcatcaaat agttttcgat cactaaagcg tagtgataca tcagaaactg taagcaattt
     4921 gtcacctcat tttatttatc taagcttcat tgtacctaaa atagtcccct ttttcaatca
     4981 gaaaagggct aatcactaca taggcaataa aacgtctttg tcttcacgtt tgtattgttt
     5041 agtcaaacta aatcctcttc ccataacttg agctgctggc atgacaacaa taaaggctgt
     5101 atcgtcaatt tcgaggattt tttcttggag agtaggtaat tcgtgacttg atacaatagc
     5161 cattaacata attttatcag aagtagtata accaccgcga ataggaagtt tagtcactcc
     5221 acgatccata acagttgtga tatattctcg aatagcttga taatctttgg aaataatcat
     5281 aacatttttg gatgagtcaa agccattttc cataacgcta atcacataac caattacgaa
     5341 aagtccaatc gtagaataca tcacgtcatc tgcagaaagt gcaataaatc ccataaggac
     5401 actaatacca tctacaattg tcattgcaac tccaagagat aaaggagagt atttatgaag
     5461 tatttgtgtt agaattccag ttcctcctgt cgaagagttt ccccaaaaaa ccattcctaa
     5521 accaatgcca cagataatac caccaaaaat agctgctaac aactgattgt gtgtcagagt
     5581 aggtaatgaa ttggttgaac ggatggcaat aggatatatc caagaaccat aaagtgtttt
     5641 aataaaattt tgttttccaa gaaagaagta acacattaat aataagggaa tattactagc
     5701 cattaaaaaa agcgacggac taatgccaaa tagagctttt ataacaactg caataccaac
     5761 cataccccct gatgcaatat gattgtcgac aaacattgta ttgaaaccaa tagctgttat
     5821 gaatgagcca attgtgacaa gtagtaaatc aatccctcgt tttttcatgc ttttaatctc
     5881 ctttataact ggttaaaaat agtagactca ttatctccta aatgtactga gaccgtcaag
     5941 tcatattttc aaaaaatctg gtgaacttga caagaagttt aaaatttcat agaataaatc
     6001 taaattagaa gagtattctt ttcatgtttt tagagagtta gtggttggtg caagctaaca
     6061 acagaaaagg tgaaatggac taatgattat ttgaaaggaa accataactt tcaggttggc
     6121 accccttacc gtgcagcttc tttcattgag aagattgaga tagtatctcg ttttggtaaa
     6181 gcagatgcta attgaggtgg taccgcgtat tacttgtaat aacgccctca cgttttaata
     6241 gcgtggggac tttttgctat atcaagagat agttagggag aaaatgatga caaaacctat
     6301 tattttaact ggagatagac caactggaaa attacattta ggtcattatg tcggaagtct
     6361 taaaaatcgt gtctttttac aaaatcaaaa caagtataag atgtttgttt tcttggccga
     6421 tcaacaggca ctgacggatc atgctaaaga atccgaatta attcaagaat ctattggaaa
     6481 tgttgccttg gattacctct ctgtcggttt ggatccgaag caatcaacga tttttattca
     6541 aagtcagatt ccagagctag ctgaattgag catgtattat atgaatctgg tatcattagc
     6601 acgtttggaa agaaatccca ctgttaaaac cgaaattgct cagaaaggtt ttggcgaaag
     6661 tattccatct ggttttttgg tttatccagt atcacaggcc gctgatatta cagcatttaa
     6721 agcgaattta gtacctgtag gtaacgacca gaaaccgatg attgaacaaa cacgtgaaat
     6781 tgtgagaagt tttaatcata cttaccatac agactgttta gtagaacctg aaggtattta
     6841 tccagaaaat gaaaaagctg gacgcttacc tggtcttgat ggcaatgcca aaatgtctaa
     6901 atcattggga aatggaatct atctttcaga tgatgcagat accgttcgca aaaaagtgat
     6961 gagcatgtat actgatccaa atcatattaa aatagaagat cctggtcaaa ttgaagggaa
     7021 tatggtcttt cattatttgg atatttttgc tagaaaagaa gatcaagctg atatcgaagc
     7081 aatgaaagag cattatcaaa gaggtggttt aggagatgtg aaaacgaaac gctaccttct
     7141 agatatttta gaacgtgaat tagcacctat tcgtgaaaga cgtttggagt acgctaaaga
     7201 tatgggagag gtgttccata tgttacaaga aggtagtcaa aaagcaagaa ctgtggcagc
     7261 caagacttta tcagaagtga agtcagcaat gggtattaat tatttttaat gttttagaga
     7321 aaaagctaag ttagtaatga taagataatt actattatca aagcaggacc taatttgtca
     7381 tttctttaca ggatagtaga gattatgttt tatatagtct tatttttgat taataaaaaa
     7441 cggataatac tgatatatta tgctgatagt gacttcagct gtaggaatat tttattgaca
     7501 aatgatttta gcgtgatatg atagtaacaa taaaaaatag accagggtaa tattccctaa
     7561 aaataaaaga aaagaggatt atctggatgt caaattggga cactaaattt ttgaaaaaag
     7621 gctacacttt tgacgatgtc ttgcttattc cggcagagag tcatgttctt ccaaatgaag
     7681 ttgatttaaa gacaaagctc gcagacaatt tgacattaaa tattcctatt attacagcag
     7741 ctatggatac ggttactggt agtaaaatgg ctattgcaat tgcgcgtgcg ggtggtttag
     7801 gtgttattca taaaaacatg tctattactg agcaagcaga agaagttcgc aaggtaaaac
     7861 gttctgaaaa tggtgtcatc attgatccat tcttcttaac acctgaacac aaggtttcag
     7921 aagctgaaga attaatgcag cgctaccgta tcagtggtgt gccaattgtt gaaactttag
     7981 caaaccgtaa gttggtcggt atcattacta atcgtgatat gcgttttatt tctgattaca
     8041 atgcaccaat ctctgaacat atgactagtg agcacctcgt tacggctgct gttggtacag
     8101 atcttgaaac tgcagaacgt attcttcatg aacaccgtat tgaaaaactt cctttggttg
     8161 ataatagcgg tcgtctgtct ggtttaatca ctatcaaaga tattgaaaaa gtaatcgaat
     8221 tcccacatgc tgctaaagat gaatttggtc gtcttctggt cgctgctgcg gtaggtgtta
     8281 cctcagatac ttttgagcgt gccgaggcct tgtttgaagc tggtgcagat gcgattgtta
     8341 ttgacacagc tcatggtcat tcggctggtg ttcttcgtaa aattgctgag attcgtgctc
     8401 atttcccaaa tcgtactttg attgctggaa atattgccac tgctgaaggt gcgcgtgctc
     8461 tttatgatgc aggtgttgat gttgttaaag tgggtattgg tcccggatct atctgtacca
     8521 ctcgtgtggt tgcaggtgtc ggtgttcctc aagtgactgc tatttacgat gctgctgctg
     8581 ttgctcgtga atatggcaaa acgattattg ctgatggtgg tatcaagtat tctggcgata
     8641 ttgttaaggc tcttgcagcc ggtggtaatg ctgttatgct tggatcaatg tttgcaggta
     8701 ctgatgaagc tccaggtgaa actgaaatct accaaggccg taagttcaaa acttatcgtg
     8761 gaatgggttc cattgcagct atgaagaaag gatcaagcga tcgttacttc caaggttccg
     8821 taaatgaagc taataaacta gttccagaag gtattgaagg ccgtgttgct tataaaggag
     8881 ctgcttcaga tattgtcttc caaatgttag gtggtatccg ctcaggtatg ggctatgttg
     8941 gcgcaggtga cattcaagaa ttacatgaaa atgctcaatt tgttgaaatg tcaggtgcag
     9001 gcttgattga aagtcatcca catgatgtcc aaatcacaaa cgaagcacca aactattctg
     9061 tgcactgata atttaattta gtaactttaa g
//
LOCUS       DATTYN010000044         9089 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.44, whole genome shotgun sequence.
ACCESSION   DATTYN010000044 DATTYN010000000
VERSION     DATTYN010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9089
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.44"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            284..1204
                     /gene="lmb"
                     /locus_tag="VB649_001707"
     CDS             284..1204
                     /gene="lmb"
                     /locus_tag="VB649_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/laminin-binding adhesin Lmb"
                     /protein_id="HEP1670635.1"
                     /translation="MKKGFFLMAMVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYA
                     MTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNL
                     KKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKE
                     LGHLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGL
                     KQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKT
                     LSPLEAAPSGNKTYLENLRANLEVLYQQLK"
     gene            1217..3688
                     /locus_tag="VB649_001708"
     CDS             1217..3688
                     /locus_tag="VB649_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEP1670636.1"
                     /translation="MKKTYGYIGSVAAILLATHIGSYQLGKHHMGPATKDNQIAYIDD
                     SKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAII
                     SEELLMTDPNYRFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVA
                     KGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVP
                     HGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPGPGRRKAPIPDVTPNP
                     GQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGL
                     IFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSDHSK
                     PSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHY
                     IGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVG
                     YMMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLP
                     MHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHE
                     ESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETF
                     VWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQAD
                     KSNEKQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINRLAQKANIDPKYLIFQP
                     EGVQFYNKNGELVTYDIKTLQQINP"
     gene            3857..4057
                     /locus_tag="VB649_001709"
     CDS             3857..4057
                     /locus_tag="VB649_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEP1670637.1"
                     /translation="MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGK
                     ELADDAKEAVEGAVDAVKEKLK"
     gene            complement(4138..4764)
                     /locus_tag="VB649_001710"
     CDS             complement(4138..4764)
                     /locus_tag="VB649_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670638.1"
                     /translation="MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTS
                     LSRVLAGFLQPKSGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYP
                     SQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQA
                     SVWKSLLEIVKDRNLGLIIISHDFDMLEKLCDACYMIEENRTQLFKHT"
     gene            complement(4748..5551)
                     /locus_tag="VB649_001711"
     CDS             complement(4748..5551)
                     /locus_tag="VB649_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEP1670639.1"
                     /translation="MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLA
                     IIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVN
                     YLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTC
                     ISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITI
                     FKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG"
     gene            complement(5563..6384)
                     /locus_tag="VB649_001712"
     CDS             complement(5563..6384)
                     /locus_tag="VB649_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670640.1"
                     /translation="MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNL
                     APSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLID
                     KIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKN
                     KAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAE
                     QPSVGIILSEAAKHISLGNWWLVIFPGLYLILVVNAFDTIGESLKKLFYPQTDHF"
     gene            complement(6381..7358)
                     /locus_tag="VB649_001713"
     CDS             complement(6381..7358)
                     /locus_tag="VB649_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670641.1"
                     /translation="MKRTTIIIIWKIIRCVTLIFGVSVLTFVLLKQSPVDPVMASVNY
                     DTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGDLGTSLVYRQPVSDIIRSRAGA
                     SFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIF
                     SVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVL
                     SSEYVLFARARGETQWQIFKHHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGL
                     GSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKA"
     gene            complement(7471..8961)
                     /locus_tag="VB649_001714"
     CDS             complement(7471..8961)
                     /locus_tag="VB649_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001869156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEP1670642.1"
                     /translation="MGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKT
                     YHLSEDGLTWSFDLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGK
                     NQVNIHLTEAHSTFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVR
                     NPYWHGKKPYFKKWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLLDIPSN
                     DVRGLSLPYVKKGVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKP
                     AYSIIDKTPFWNPKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTN
                     DQLRANLAVEVAEQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHH
                     PSLAGKGWTNITFYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPN
                     VWLVSLNHTYIGDKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK"
BASE COUNT         2977 a         1768 c         1821 g         2523 t
ORIGIN      
        1 agtgatggta tttcctaaaa aagacctcag ttatcgtcgc aaacaacggt atatttctgt
       61 ccatttggaa gattatttag tccaattatt tggagaaaga ggctaagcag atgattgatt
      121 taaaaaggaa tcttttcaaa attgatgtcc gggcacaaaa ggatgaagag aaagttttca
      181 tgcgtacggc gtgtaaaaga tggtagttgc cattgacaaa gcattgataa aggagtaaaa
      241 ttaactggtt aataactggt taaattataa ttgaggaggt actatgaaaa aaggtttttt
      301 tctcatggct atggtcgtga gtttagtaat gatagcaggg tgtgataagt cagcaaaccc
      361 caaacagcct acgcaaggca tgtcagttgt aaccagcttt tacccaatgt atgcgatgac
      421 aaaagaagta tctggagacc tcaatgatgt gaggatgatc caatcaggtg caggcattca
      481 ttcctttgaa ccgtctgtaa atgatgtggc agctatttat gacgcggatt tgtttgttta
      541 ccattcacat accttagaag cttgggcaag ggatctagac cctaatttaa aaaaatcaaa
      601 ggttgatgtg tttgaagcgt caaaacctct gacactagat agagtcaaag ggctagaaga
      661 tatggaagtc acacaaggca ttgaccctgc gacactttat gacccacata cctggacaga
      721 tcccgtttta gctggtgagg aagctgttaa tatcgctaaa gagctaggac atttggatcc
      781 taaacacaaa gacagttaca ctaaaaaggc taaggctttc aaaaaagaag cagagcaact
      841 aactgaagaa tacactcaaa aatttaaaaa ggtgcgctca aaaacattcg tgacgcagca
      901 cacggcattt tcttatctgg ctaaacgatt cggcttgaaa caacttggta tctcgggtat
      961 ttctccagag caagagccct ctcctcgcca attgaaagaa attcaagact ttgttaaaga
     1021 atacaacgtc aagactattt ttgcagaaga caatgtcaat cccaaaattg ctcatgctat
     1081 tgcgaaatca acaggagcta aagtaaagac attaagtcca cttgaagctg ctccaagcgg
     1141 aaacaagaca tatctagaaa atcttagagc aaatttggaa gtgctctatc aacagttgaa
     1201 gtaaaggaga ttattagtga agaaaacata tggttatatc ggctcagttg ctgctatttt
     1261 actagctact catattggaa gctaccaact tggtaagcat catatgggtc cagcaacaaa
     1321 ggataatcag attgcctata ttgatgatag caaaggtaag gcaaaagccc ctaaaacaaa
     1381 caaaacgatg gatcaaatca gtgctgaaga aggcatctct gctgaacaga tcgtagtcaa
     1441 aattactgac caaggctatg tgacctcaca cggtgaccat tatcattttt acaatgggaa
     1501 agttccttat gatgcgatta ttagtgaaga attgttgatg acggatccta attaccgttt
     1561 taaacaatca gacgttatca atgaaatctt agacggttac gttattaaag tcaatggcaa
     1621 ctattatgtt tacctcaagc caggtagcaa gcgcaaaaac attcgaacca aacaacaaat
     1681 tgctgagcaa gtagccaaag gaactaaaga agctaaagaa aaaggtttag ctcaagtggc
     1741 ccacctcagt aaagaagaag ttgcggcagt caatgaagca aaaagacaag gacgctatac
     1801 tacagacgat ggctatattt ttagtccgac agatatcatt gatgatttag gagatgctta
     1861 tttagtacct catggtaatc actatcatta tattcctaaa aaagatttat ctccaagtga
     1921 gctagctgct gcacaagcct actggagtca aaaacaaggt cgaggtgcta gaccgtctga
     1981 ttaccgcccg acaccaggcc caggtcgtag gaaagcccca attcctgatg tgacgcctaa
     2041 ccctggacaa ggtcatcagc cagataacgg tggctaccat ccagcgcctc ctaggccaaa
     2101 tgatgcgtca caaaacaaac accaaagaga tgagtttaaa ggaaaaacct ttaaggaact
     2161 tttagatcaa ctacaccgtc ttgatttgaa ataccgtcat gtggaagaag atgggttgat
     2221 ttttgaaccg actcaagtga tcaaatcaaa cgcttttggg tatgtggtgc ctcatggaga
     2281 tcattatcat attatcccaa gaagtcagtt atcacctctt gaaatggaat tagcagatcg
     2341 atacttagct ggccaaactg aggacaatga ctcaggttca gatcactcaa aaccatcaga
     2401 taaagaagtg acacatacct ttcttggtca tcgcatcaaa gcttacggaa aaggcttaga
     2461 tggtaaacca tatgatacga gtgatgctta tgtttttagt aaagaatcca ttcattcagt
     2521 ggataaatca ggagttacag ctaaacacgg agatcatttc cactatatag gatttggaga
     2581 acttgaacaa tatgagttgg atgaggtcgc taactgggtg aaagcaaaag gccaagctga
     2641 tgagcttgct gctgctttgg atcaggaaca aggcaaagaa aaaccactct ttgacactaa
     2701 aaaagtgagt cgcaaagtaa caaaagatgg taaagtgggc tatatgatgc caaaagatgg
     2761 caaggactat ttctatgctc gtgatcaact tgatttgact cagattgcct ttgccgaaca
     2821 agaactaatg cttaaagata agaagcatta ccgttatgac attgttgaca caggtattga
     2881 gccacgactt gctgtagatg tgtcaagtct gccgatgcat gctggtaatg ctacttacga
     2941 tactggaagt tcgtttgtta tccctcatat tgatcatatc catgtcgttc cgtattcatg
     3001 gttgacgcgc gatcagattg caacaatcaa gtatgtgatg caacaccccg aagttcgtcc
     3061 ggatgtatgg tctaagccag ggcatgaaga gtcaggttcg gtcattccaa atgttacgcc
     3121 tcttgataaa cgtgctggta tgccaaattg gcaaattatc cattctgctg aagaagttca
     3181 aaaagcccta gcagaaggtc gttttgcaac accagacggc tatattttcg atccacgaga
     3241 tgttttggcc aaagaaactt ttgtatggaa agatggctcc tttagcatcc caagagcaga
     3301 tggcagttca ttgagaacca ttaataaatc tgatctatcc caagctgagt ggcaacaagc
     3361 tcaagagtta ttggcaaaga aaaacgctgg tgatgctact gatacggata aacccaaaga
     3421 aaagcaacag gcagataaga gcaatgaaaa gcaacagcca agtgaagcca gtaaagaaga
     3481 agaaaaagaa tcagatgact ttatagacag tttaccagac tatggtctag atagagcaac
     3541 cctagaagat catatcaatc gattagcaca aaaagctaat atcgatccta agtatctcat
     3601 tttccaacca gaaggtgtcc aattttataa taaaaatggt gaattggtaa cttatgatat
     3661 caagacgctt caacaaataa acccttaacc aaaagaagat ctcattgtta aagcactgct
     3721 ttgttaaagc aagttacggt gattttgaag tcattttatg taacgagtag tgataaaagt
     3781 tggataatag cggttttctt ttgcaaagaa atggtatcca tgttagaata ataaaaaaaa
     3841 gaggaggatt ctaatcatgt cagaagaaaa attaaaatca aaaattgagc aagcatctgg
     3901 tggcctaaaa gaaggtgctg gtaagttgac aggtgataaa gagctagaag caaaaggatt
     3961 tgttgaaaaa acaattgcta aaggcaaaga acttgcagac gatgcaaaag aagcggttga
     4021 aggtgctgta gatgccgtta aggaaaaatt aaaataatta aaaaaaccag ctgtaagctg
     4081 gttttttaat ggtgtgattt tgttaggaaa agactcaata ggtaataacc gtaggtgtta
     4141 ggtatgcttg aacagttgag tacgattctc ttcaatcata tagcacgcgt cacagagttt
     4201 ttctaacata tcaaaatcat gactaataat gatgagacct aaatttctat cctttacaat
     4261 ctccaacagg cttttccata cactagcttg tgtaatgcta tccaacatag tagtcatttc
     4321 atctgcaata aggtatttcg tctctggatg taatgaacgc acaatcgaaa agcgttgcaa
     4381 ttcccctccc gagagttcac taggacgacg ctttagccat ttttcttgaa tgccaaaagc
     4441 atctcgcaaa tcttgacttg gatagtaggc ttcttccaaa ctttttttca taggccataa
     4501 aggattcatg gtttgttcag gatgttgttg gataagttgt acaggtctaa atgctttgtt
     4561 aggcaaatga ctgccatcaa ctaatacttc accagattta ggctgcaaaa aaccggcaag
     4621 cactctggat aaactcgttt ttccacaccc actttgtcca aatatcccta agatttgacc
     4681 aggtgctacc tctaaatcaa tctccttaaa aagccattga tcttttttat gataaaagcc
     4741 aagcttttta gcctctaagg tcatgagtaa ctcctttcaa aaagtcttgc tgagggagtg
     4801 tgcgccataa acgtctcgca aattctgttt gtaattgctc cccacctccg ctaaaaaagc
     4861 tagctggggc tgtttcaata gcttttccct ctttaaaaat agttatacga tccgcaattt
     4921 gactagctgc tacaatatca tgagtgataa atatgacgct tattccttta tctgcaaagg
     4981 agcgtagttg atctaaaacc atttgcagag catctggatg taatccaggg gtgggctcat
     5041 ccgcaataat caaagaaacc gtatcactaa tacacgttgt aaacaaaaca cgtcggagca
     5101 ttccgccaga aagttggaaa ggatacaagt caccatcact ttcttttaat ccaaactgtt
     5161 gaaataatcc ttcttgagta gccttagcat tttctgagat acccaagcgc acctgatgct
     5221 tgactttcat agatggatct aaataattaa cggattgtgg aatcaacgtc atttcttttc
     5281 ctcgcaactg tttgatgcgt ttagaagtta gtgattgacc acgataaatc atatctcctg
     5341 ttacagctgc atttttagga agaatatcca taatagcatg tgctaataaa ctcttgcctg
     5401 aaccactagc acctataata gctaataact cacctttttt aacttctaaa ttcagcgctt
     5461 ggatcggtgt ggattgaaat ggttttaaaa atcttccgta ttgagtgaag gtgatggaga
     5521 ggtctttaat gcttaataat gtttctgtca tatctctacc tcctaaaaat gatccgtttg
     5581 agggtaaaag agtttcttta aagattctcc gatagtatca aaggcattga caactaaaat
     5641 aagataaagg cctggaaaaa tcaccaacca ccaattgcca agagagatat gcttagctgc
     5701 ttctgacaaa atgataccaa ccgaaggttg ttcggcagaa aggccaaatc ctaagaaagt
     5761 catggatgct tcatgcaaga tgacgtgcgg aaataagagg ataaacccaa tgaaaatttg
     5821 agaagcaatc aaaggcagga tatgatgcct cacaatataa taaggcgttt ttcccatgct
     5881 tttagagagc tggacaaagg ctttattctt tagatcatag acttcattgc ggataagcct
     5941 tgctagagag ggccaatggg taacagccgt tgcaatgata accccttgag cccctttccc
     6001 aacaacaaaa gaaatgagaa tcataaaaat caaatgaggc ataccaataa acaaatcaac
     6061 caaccaggct attattttat caataaggct atttcctaga cctgcaagca ctccaaaaac
     6121 ggtcgcaaga aagactccca taagggcacc taataagccg acttgtaaag agaaataaag
     6181 ccctttaatc gttctgacaa acatatccct acctaaacca tctgtcccaa aaagatggtt
     6241 taatgaagga gcgaggttgc gtaaagctgc attggtttct aaaggcgtcc tatagaaata
     6301 aagatttaag gctagaatac taagaatgag agaaatggcg atacctagtt gccataaaac
     6361 catcgttcga cgtttcaata tcatgctttt ctccttaact gtggattgat gatgctattt
     6421 aaaatatccg caataagatt gcccgcaaaa acaaataatg tccctatcat cacaatagct
     6481 agaaggagcg gtgtatcact tttaagtcct gcttcagtga gggtagaccc taagccagga
     6541 tatgagaaaa cttgctcagc aagaacagat cctccaaaca attctccaaa ataggaaaaa
     6601 tgcagtgtaa tagctggtac gatagcattt ctaaggcaat gatgtttaaa aatttgccac
     6661 tgtgtttccc cacgcgctct ggcaaataag acatattcac tagaaagcac cgacatcatt
     6721 ttagttctcg tatgaagggt gacattggca atgcctagaa tacttagtgt gaaaacaggt
     6781 aacataaggt gcttaatccg atcagctaac gtaatatctt gactcaaagt gcctatcggg
     6841 gaagaaatac caatcgggaa ccaccccaac tggacagaaa agattaataa aaaaatgagg
     6901 ccaatccaaa acgttggtac tgatatctga aggtatgaaa accacctgac aactcggtca
     6961 agtaatttcc cttgatggaa agcggataac gttcctaaga taaatccaat aagacccgat
     7021 aagatccaag agagtcccat aagtatgaaa gaagcacctg cccgtgatct aataatatca
     7081 ctaacaggtt gccgataaac gagcgaggtc cctaaatctc cctgtatcac atttttcaac
     7141 caaataaaat attggactag agctggctta tccaagccat agtggtgagc aatcgctttg
     7201 tactgagcag gggttagtga tgtgtcataa ttgacacttg ccatgactgg atctactgga
     7261 gattgtttta acaaaacgaa ggtcaaaaca gataccccaa aaataagcgt gacacatctg
     7321 atgattttcc agatgataat aatggtagta cgtttcacaa tgaaatctcc ttaatcgata
     7381 agaaaaggag ccgaggaaac gatcagcaca gttttgtgta tcttgttttc tcagactcca
     7441 aacttaaagt cgctgtatta actaaacgcg ttacttagtt gattcatccc aagtccactc
     7501 ggcaatgtta gtcaataatg accaatcatg accatgactg tggacgcctt gtttacctac
     7561 attgatacgt ttatcaccaa tataagtatg gttaaggctc accaaccata catttggcaa
     7621 atctccaaga gtagaagcac ctgttttgcc atcccactgc gctaacttcc aatattcgtt
     7681 agctttgtca aggtcagaag atgtcattgc tttgtcaagg tacttagtca cggtaggatt
     7741 gttataaaac gtaatattgg tccaaccttt acctgctagg cttggatgat gtgattcata
     7801 aaattgctgc gcgtgatgac gtcctccggc ataaagtaag gctgagtcat gtgacttcgt
     7861 tgccatttca tcccagttac tagctttgag tttaatagta attcctaggg ctttggcttg
     7921 ctctgctact tcaacggcta agttcgctcg caattgatca ttagtagggt agtacagatc
     7981 aaacgctgca tcaaggtcac cttttttacg gctaccgtct gcttgttctt tccatcccgc
     8041 ttttgtcaac aattgcttag ctttagctac tttattatct ttaatggctg tttttggatt
     8101 ccaaaatggt gttttatcaa taattgaata agctggttta ccataaccat ttaaaaccgt
     8161 atcgagaact ttttgcctat ttaaaccaat agtcaaggct tttcggattg ctggatcact
     8221 agtgacatca tttcctacag gataaccatc aggagaatca gtgatgacgc cttttttcac
     8281 ataaggtaat gataagccgc gcacatcatt tgatggaatg tcaaggaggc gggtgccttt
     8341 gactttcttg ctagcaagtt ctggtgtcgc gtagatcata tcaacatcac cagattctaa
     8401 agcagctagt gctgtgtttt catcaagtaa gacccaagtc cattttttaa agtatggttt
     8461 tttcccatgc caataagggt tacgaacaaa aatagcttgt tctccagcct tatattcttt
     8521 taccatgtaa ggtcctgaac cgataggatt gctcttatac ttatcattgt aatgtttttt
     8581 agggacgatt gggatttcag tcaactgtgc tgtaaatgtc gaatgcgcct cagtcaaatg
     8641 gatattgacc tgatttttcc caactacttc aacgttcttg atgaaggtta gatcccaagc
     8701 ctttccatct gctttcaaca tatcataagt aaacttaaca tcatcagcag taacaggctc
     8761 accatttgag aatttaaaat catcatgcaa gtcaaacgac caagtcagcc catcttcaga
     8821 gagatggtat gttttagcaa gctctccttt tatatctagt tcaggagaac gtttcaatag
     8881 agtgctatga gtgatattcc cttcattgtg gactccataa cggtcctttg gatcgaattc
     8941 atgagggagc tttgccccca tagaaacgac aagttcgtct tttggacgtt gtttgcgctg
     9001 acgttctttt gtttgaggct tttgttgttg acatgcaact aaaataagcc cagtcaaaaa
     9061 taacgtgata atagagaagt attttaggt
//
LOCUS       DATTYN010000045         7208 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.45, whole genome shotgun sequence.
ACCESSION   DATTYN010000045 DATTYN010000000
VERSION     DATTYN010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7208
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.45"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..227
                     /locus_tag="VB649_001715"
     CDS             <1..227
                     /locus_tag="VB649_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP1670643.1"
                     /translation="PSTSRKGNSPDNGMMESFFGILKSEMFYGLETTYQSLDKLEEVI
                     TDYIFYYNNKRIKAKLKGFSPVQYRTKSFQ"
     gene            complement(276..1007)
                     /locus_tag="VB649_001716"
     CDS             complement(276..1007)
                     /locus_tag="VB649_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEP1670644.1"
                     /translation="MRLDKFLVATGVGTRSQVKLLLKKKAIFVNQKVETSAKAHIDEY
                     KDLVTYQGTPLVYESFVYYLLNKPSGYVSATQDRQQATVMELLDDTARQKAVFPVGRL
                     DKDTRGLLLLSNNGQLAHDLLSPKKHVTKEYLAKVAGIMTEADKDYFARGISLKDHQC
                     LPAHLEVLASDLQQQTSLVKITIQEGKFHQVKRMVAACGKGVLDLQRLSMGPLKLDPS
                     LAEGEFRRLTPEELQSLAPYCQSSL"
     gene            1122..1487
                     /locus_tag="VB649_001717"
     CDS             1122..1487
                     /locus_tag="VB649_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEP1670645.1"
                     /translation="MTIYSHTYETRPNHSAKAMGSGTLNVLATPALVAFMENASYLFA
                     QEQLDSDFTTVGSEIAIQHLAASAIGDPVTIIITALKEEGRKYDFRLEAFVGEQLIGK
                     ACHTRVRVNSKHFMAKVAE"
     gene            complement(1607..2827)
                     /locus_tag="VB649_001718"
     CDS             complement(1607..2827)
                     /locus_tag="VB649_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP1670646.1"
                     /translation="MSTLSLDTTNKRALVAAIAASGTDDLNVMFLAFSMSSIMTDLGL
                     SGTQGGWIATITNLGMLVGGLLFGLLADRHHKFKVFKWTILLFSVATGLIYFTQSLPY
                     LYLMRFIAGIGVGGEYGVAIAIMAGIVPPEKMGRMSSLNGIAGQLGSISSALLAGWLA
                     PSLGWRGLFLFGLLPILLVIWMTLAIDDQKIWDHYGQEEEECSQPIKINELFKTKSLT
                     AQTLALMVMTTVQIAGYFGMMNWLPTIIQTSLNLSVKSSSLWMVATIVGMCLGMLCFG
                     QLLDCFGPRLIYSLFLLASSICVYLFQFANSMASMVIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNVILNVGRALGGFSSVAIGSILDASGISMVMIFLASLYVISFGAMW
                     SIGQLKAERYQQLR"
     gene            3200..4684
                     /locus_tag="VB649_001719"
     CDS             3200..4684
                     /locus_tag="VB649_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEP1670647.1"
                     /translation="MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHA
                     ARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKF
                     NTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMND
                     IGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTL
                     AKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKE
                     LGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK"
     gene            complement(4789..5190)
                     /locus_tag="VB649_001720"
     CDS             complement(4789..5190)
                     /locus_tag="VB649_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEP1670648.1"
                     /translation="MSDLTQEMTLNVISIFDNYQIELAEKGHLILSTEVTETALNYYG
                     NAHGGYLFTLCDQVGGLVARTTGVESVTLQANANYLKAGHKGDKLMVEGRLVHGGRTT
                     QVVDVTIHNQTGALLTKTSLTMFVTGRRHNG"
     gene            complement(5275..6052)
                     /locus_tag="VB649_001721"
                     /pseudo
     CDS             complement(5275..6052)
                     /locus_tag="VB649_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060407.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
     gene            complement(6399..7046)
                     /locus_tag="VB649_001722"
     CDS             complement(6399..7046)
                     /locus_tag="VB649_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEP1670649.1"
                     /translation="MAMISVQNVSKKYGSRVIFKDLSFDVEEHEFVALVGPSGTGKST
                     LLNMIGLLDSFDSGSILINGKILPKVNSRAAVTYRKNVINYLFQSNALISTASVKDNL
                     MLAMTFTDFSKQEKEKMIKDTLQFVNLENRLNSLVNELSGGEQQRIAIVRAILKPGNI
                     ILADEPTGSLDPDMAQKSFDLIRSLRDKFGKTIVIVTHNFEHAKQCDRVISLVSD"
BASE COUNT         2311 a         1538 c         1256 g         2103 t
ORIGIN      
        1 tgccatccac gtcccgcaaa gggaatagcc cggataacgg catgatggaa tccttctttg
       61 gcattctcaa atctgaaatg ttttatggac tcgagacaac ttatcaatca cttgacaagc
      121 ttgaagaagt tattacagat tacatttttt actacaacaa caaacgaatt aaagcaaaac
      181 taaaaggatt tagtcctgtc caatacagaa ctaaatcctt tcaataatta tttgtccaac
      241 tttttggggt cagtactgac aggggaggtt tctttttata gtgagctctg acaataaggt
      301 gccaggcttt gcaattcctc aggcgtcagg cgcctaaact ccccttctgc aaggctaggg
      361 tctagtttta atggtcccat gctgagacgc tgcaagtcaa gcactccctt cccacaggct
      421 gctaccatgc gtttcacctg atggaatttt ccttcttgta tggtaatttt aaccaaactt
      481 gtttgctgct gtaaatcact agcaagcact tctaaatgag caggtaggca ctggtgatcc
      541 tttaaggaaa tacctctagc aaaataatct ttatcagctt cagtcatgat gcctgctact
      601 ttagccaagt actctttcgt aacatgtttt ttaggggata aaaggtcatg ggctagttgt
      661 ccattattgg acaagagcaa aagtccacgg gtatccttat ctaacctacc cacaggaaaa
      721 actgcttttt gcctagccgt gtcatctaac aactccataa cagtagcctg ctgtctgtcc
      781 tgggttgctg acacataccc tgacggcttg tttaacaggt aataaacaaa ggattcatag
      841 accaagggcg tgccttgata cgtcaccaaa tccttgtatt catcaatgtg tgctttggca
      901 gaggtttcaa ccttttgatt gacgaaaata gccttctttt ttaagagaag tttgacttga
      961 ctcctagttc caacaccagt tgccactaaa aatttatcta agcgcatcat aaccctttca
     1021 aagaaaattc attattaagt ataacataaa aaaacagtag tttcatgact gtaagcgctt
     1081 aatatattat aataggctta tagaaacgag gagattaact tatgactatt tattctcaca
     1141 cttatgaaac ccgtcccaat cattcggcta aagccatggg ctcaggaacg ctgaatgtcc
     1201 tagctactcc tgctcttgtt gcttttatgg aaaatgcttc ttacttattt gcccaagaac
     1261 agctcgacag tgactttaca acggttggca gcgagatagc tatccaacat ttggcagctt
     1321 cagccattgg agatcctgtt acaatcatca ttacagccct taaagaagaa ggccgaaaat
     1381 acgatttccg cttggaagct tttgtgggag aacaactcat tggaaaagcc tgtcatacta
     1441 gagttagggt gaacagtaaa cattttatgg ccaaagtagc ggagtaaaac aaaagaaaag
     1501 aaccaaaaag gtaagcaatc cctaagtgct tacctttttg gttatctcaa tcaataaaat
     1561 agttttgtga gtgaaagtaa ctcaaatact aacacccatc tctttgctaa cgcaattgtt
     1621 ggtagcgttc tgcttttaac tgaccaatag accacatggc tccaaaacta atcacataca
     1681 gagaagctag gaaaatcatg accattgaaa tacctgaggc atctaaaata ctaccaatag
     1741 caacggacga aaatcctcct agagcacggc caacattcaa aataacatta ttagccgtgg
     1801 atcgaatgtg atggggataa agtctggtaa tcatagcccc gtagccagca aacatcccat
     1861 tgacaaaaaa accgacaatg gcacctccaa taaccatact cgccatggaa ttggcaaatt
     1921 gaaaaaggta aacacaaata gatgatgcta ataaaaagag ggaataaatc agacgtggac
     1981 caaagcaatc taaaagctga ccaaaacaca gcatccccaa acacatgccg acaatagtag
     2041 ccaccatcca caaggacgaa ctttttactg aaaggtttaa gcttgtttga ataatggttg
     2101 gcaaccaatt catcattcca aaatagcccg caatctgcac agtcgtcatg accattaaag
     2161 caagggtttg agctgttaag gattttgttt tgaatagttc attgatttta attggttgac
     2221 tgcattcttc ctcctcttgc ccataatgat cccaaatttt ttggtcatct atggctaaag
     2281 tcatccaaat caccaagaga atcggaagta atccaaagag aaaaaggcca cgccagccta
     2341 gacttggagc cagccaccct gctaaaagag ccgaactaat ggagccaagc tggccagcaa
     2401 taccatttaa agaagacatc cgacccattt tttctggtgg tacaatccct gccattatgg
     2461 caatggctac accatactca cctccaactc ctatgccagc aataaatcgc atcaggtaca
     2521 ggtagggcaa agactgggta aaataaatta atcctgttgc tactgaaaac agtaaaatcg
     2581 tccatttaaa gaccttaaac ttgtggtgcc tatcagccag caacccgaat aagaggcctc
     2641 ccaccaacat tcctaaattg gtaatggtcg caatccagcc accctgagtg ccactaagac
     2701 ccaagtctgt cataatggaa gacatggaaa aggcaagaaa catgacattc aagtcatccg
     2761 ttcctgaagc tgcaatagct gccactaaag ctcgcttatt tgtagtgtcc aatgataatg
     2821 ttgacataat tgtctccttc ttaatagtag ctcactgact accttaatta attgaatacc
     2881 ctttgtccaa aggtcaaaaa agacttggaa acaagtccgc aagtccatca aagttcacta
     2941 aataataaga gatgacaaaa aaactctctt tactgttaag actttcatgc ttcacggaac
     3001 atgtttaaag tagtatttaa ttgttactag tatagtaaag ctcattttaa ttgtcaagtt
     3061 cttttgaaca tagcagatac atttttattc taagaaccaa gcctaagttt ttttaaaaag
     3121 tcacaaaatg aggtatccct gcaaaaaacc ttttctttct tggaatttct ttgttataat
     3181 gctttacaga ggtgaaaaaa tgaagactat tgcttttgat tctaacaagt atttaaactt
     3241 gcaaagagat catattttag aacgtatcag ccaatttgat ggcaaacttt acatggaatt
     3301 tggtggtaaa atgttagaag attaccatgc tgcccgtgta cttcctggct atgaacctga
     3361 caataagatt aaattactca aagagctcaa agaacaagtc gaaattgtaa ttgccattaa
     3421 cgctaataat attgaacatt ctaaagcgcg tggtgattta ggcatttctt atgaccaaga
     3481 agtctttcgc ttaattgaca aatttaacac gttagatatt tacgtaggtt ctgtcgttat
     3541 tacccaatac aataaccaac ccgctgcaga tgcctttcgc aagcaactcg aaaaaaatgg
     3601 cattgcttct tacctgcatt atcctatcaa gggctacccg acagatatta atcatattat
     3661 ctcatctgag gggatgggga aaaatgatta catcaaaacg agtcgtaacc ttatcgttgt
     3721 tacagcacca ggccctgggt ctggaaaatt agccacttgc atgtcccaaa tgtatcacga
     3781 ccaaatcaat ggggttaagt ctggctatgc taaatttgaa accttcccag tttggaatct
     3841 tcctcttcat caccctgtca atctggctta tgaggcagcc acggcagacc tagatgatgt
     3901 gaatatgatt gaccccttcc atttggaaac ttatggcaaa acggccgtta attacaaccg
     3961 tgatatcgag gtctttcctg tcttaaatcg gaccttcgag cgtattttga gcaagtctcc
     4021 ttatgcctca ccaaccgata tgggtgttaa catggttggt ttttctatcg tcaatgaaga
     4081 agctgctatc gaagcttcta aacaagaaat catccgtcgt tattaccaaa ccctcgtgga
     4141 ttttaaggca gagcgggtca cagaatctgc tgtcaaaaaa attgagctct tgatgaatga
     4201 tatcggtgtc acccctgacg atcgtcacgt tactgtagct gctcatcaaa aagcagagca
     4261 aacaggccaa cctgcccttg ctctccaact accaaatggg cagattgtga caggtaaaac
     4321 atctgaactc tttggaccaa ctgcagctgt tatcatcaat gcgattaaaa ccttggcaaa
     4381 gattgataaa accactcatt tgattgaacc cgaatacgta aaacctattc aaggactcaa
     4441 agtgaaccac ttaggcagtc acaatccgcg gcttcattcc aatgaaattc tgattgcgtt
     4501 agccattact gctatgacta gtgaagaagc taatctagcc atgaaagaac tcggcaattt
     4561 gaaaggtagt gaagcccatt ctaccgttat cttaaccgaa gaagataaaa atgtactccg
     4621 aaaacttggg gtcaatatta cctttgaccc tgtttaccaa catcacaaac tttaccgtaa
     4681 ataaaccgta accacccgtc taacggatga tttatggtat ctctcaataa aggaaaaaag
     4741 tcccaattct cagagagttg ggactttttt cctttattga ttcattaatc acccgttatg
     4801 acgtcggcca gtcacaaaca tggtcaagct tgtttttgtt agaagagctc ctgtttggtt
     4861 atgaatcgtc acatcaacca cctgcgtggt tcgacctcca tgaaccaatc gaccttcaac
     4921 catcagcttg tctcccttgt gccctgcttt taaatagtta gcattggcct gtaaggtgac
     4981 agattctacg ccagtagttc tagcaaccaa accacctact tgatcacata gggtgaaaag
     5041 ataaccacca tgggcattcc cataataatt caaagccgtc tcagtcactt cagtacttaa
     5101 aataaggtgt cctttttcag caagttcaat ttggtaatta tcaaaaatac taataacatt
     5161 taaggtcatc tcttgtgtta aatctgacat tgtttttctc ttttctaagc ttagtctaaa
     5221 agcaatacaa gcctcattat actacaaata ggaacagaag gcagagctca tgtttcaaaa
     5281 atcagtagcc tttccatcct tttctagcgt attgagcact tccaagcata aatggagcgc
     5341 aaaactaaag gaatcagcgc cccagttgcg ttgatcgtaa acctctacat ctgctagagt
     5401 atctgctgta aataagagtt gcccccaaag gatgcctctt aattgagcta ctgctgctaa
     5461 ggcagaacat tccatctcaa caaccgaaca cccttcttcc tggcgataag ccactttttc
     5521 tttggtttct cggtaaaaac catctgttga ccaggtgatg acctcttgat aagctaaccc
     5581 ctgtgctaaa agcttttctc aatcagtcta agcatcttag gatcaatatc aatataatga
     5641 gatggtgcca cgtaatgata acttgttcct tcatctcgca aagccttaac tgggactaaa
     5701 aaacggtttt ctgcgatagg aaccaaaacg ccacaggttc ctgtactgat catttcttta
     5761 accccataac caatcagcca gtccatgaat tgcgccgcag gagctgagcc aacgggagct
     5821 tgagctaggc aaatgtcttg gcttttataa gatatctgat aaacagggta aacctttgtg
     5881 gctgaaatga attctgctac ttttttacct tgatggtcta aagcaaaagc ttcaatctcg
     5941 tcttctaaga aagcgtagac acacttagct ggaagctaaa tagctagata atgacggctg
     6001 atggattact atcacattct aaaaggggaa tctcgtgttt ggtaataggc attcgtttct
     6061 ccttattttt gtcatgtgga ggcagctacc ttactccttg attagcaaca ctacgcactc
     6121 cacacggtaa gtagccaaaa atacattagc taaagtatac attttctagc tctgttaagt
     6181 ttaattcttc gtcaagttgt atagttaaat tacccaataa tattgcagga aggttaatat
     6241 atttttttgt aaagaatgta ataagactac tgcaactaat atctcatcgg agtaaacaga
     6301 aatctgaaaa atatcattta ctaaattttg tatgataagt atttgttttt cgtctctttt
     6361 aatgatataa aactcgatat cattcattca atctctcctt aatcagatac taaagaaata
     6421 actctatcac attgttttgc atgttcaaaa ttatgtgtaa caattacaat tgtttttcca
     6481 aatttatctc tcaacgaacg gattaagtcg aatgattttt gtgccatatc aggatctaat
     6541 gatccagttg gttcatcagc taatataata ttaccgggct ttaagatagc tctaacaatg
     6601 gcaattcttt gttgttcacc ccccgataat tcattaacaa gactatttaa tctattctct
     6661 aggtttacaa attgtaaagt atcctttatc atcttttctt tctcttgttt tgaaaagtca
     6721 gtaaatgtca tagcaagcat aagattatct ttgacactag ctgttgagat aagagcattt
     6781 gactgaaaca aataattaat gacattttta cgataagtaa cagctgcacg tgaattaact
     6841 ttaggtaaaa ttttcccatt tatcaaaatc gatccactat caaaactatc taatagacct
     6901 atcatattga gtaaagtaga ctttccagtt ccagatggac caactaaagc tacaaattca
     6961 tgttcctcaa catcaaaact taagtcttta aaaattactc ttgaaccata cttctttgac
     7021 acattttgta ctgaaatcat agccatcata tcacccctta aatgattgta aaatacttcc
     7081 tctttctttg cggaacacat tgaaataaag aaagaacatt tggaaagtag ttgtaattag
     7141 agttaaaact atccctagtt tagaacccaa aattatagaa gttaaaagtt ctataataga
     7201 gacaccaa
//
LOCUS       DATTYN010000046         6993 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.46, whole genome shotgun sequence.
ACCESSION   DATTYN010000046 DATTYN010000000
VERSION     DATTYN010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6993
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.46"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            129..1373
                     /locus_tag="VB649_001723"
     CDS             129..1373
                     /locus_tag="VB649_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEP1670650.1"
                     /translation="MKIVQGVQLHLIKTKQFKTNHITFRFSGDLNQKTVAKRVLVAQM
                     LATANECYPTVRQFREKLARLYGASLSTNVLTKGLVHIVDIDITFIQDRYACNGEKIL
                     DEMIQFLKDILFSPLLSIAQYQPKVFETEKNNLINYIESDREDSFYYSSLKVKELFYC
                     NKNLQMSEYGSPELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRVVQLIHQFPL
                     DNRNKNLNFFHLQNSVNIIKESIEKRAVHQSILQLAYHFPSVFGQRDYYALVLLNGLL
                     GSFAHSRLFIKIREEEGLAYSIGCRFDSYTGLFEIYTGIDSQHRTKTLQLIIQELNAI
                     KMGRFSEQLIKKTRSMLLNNALLSEDYNKNIIERIYTSSYINSSYSIKNWIKGVNEVN
                     KADIIKVANLLKLQTVYFLEGI"
     gene            1375..2664
                     /locus_tag="VB649_001724"
     CDS             1375..2664
                     /locus_tag="VB649_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEP1670651.1"
                     /translation="MTKLVKINYPNIDEDLYYVKLENGLTVYFIKKIGFLEKTAMLTV
                     GFGSLDNKLTVDDESRDAPAGIAHFLEHKLFEDESGGDISLKFTQLGAETNAFTTFNQ
                     TSFFFSTASKFQENLELLQYFVLSANITDESVSREKKIIGQEIDMYQDDADYRAYSGI
                     LRNLFPKTSLANDIAGSKESIQKITKILLETHHTYFYQPTNMSLFIVGDIDIDETFLA
                     IQRFQTTLSYPDRKRVTVDPLHYYPVIKSSSVDMDVTTAKLVVGFRGYLTLTQHSLLT
                     YRIALKLFLSMLIGWTSKIYHTLYEDGKIDDSFDVDVEIHHNFQFVLISLDTPEPIAM
                     SNYIRQKLATIKISKEFTNEHLNLLKKEMYGDFIQSLDSIEHLTHQFSLYLSDSDKET
                     YFDIPKIIERLTLKDVVTIGKAFFEKADASDFTVFPK"
     gene            2714..3739
                     /locus_tag="VB649_001725"
     CDS             2714..3739
                     /locus_tag="VB649_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEP1670652.1"
                     /translation="MSEKSLGEVLRESRVGKNITLDDIELKTGISSHYLLAMELDQFK
                     IIPEEKFDQFLKEYADIVELDFNTLKRRYCYQVNSKKDSDIKSVTEIVEEKLSKKRLQ
                     EKLLSHQSMGYGQPLEVSKNKETLVIPVKTVGLDSKSPLKTISPVSQFKSDNRLIPKK
                     NVSRMRRNSTDSRSKTSLFPIAILGTIAFAIISVIILGVWQQFEKSQRAKEAEVALLK
                     ASEQSTNGLKNNSNDRKTQVTTEGSGNYLIATVTKSKETVDISVSLTEAQSSWISLTN
                     SEIGEGGITLTQDSPTYTATLPAEITESLLTLGVTNGVSVTIDGQPVDLSPLTSTDLS
                     YITFKIQ"
     gene            3753..4295
                     /gene="pgsA"
                     /locus_tag="VB649_001726"
     CDS             3753..4295
                     /gene="pgsA"
                     /locus_tag="VB649_001726"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEP1670653.1"
                     /translation="MIKKENIPNLLTLVRIAMIPFFLFITSSSNKVGWHIFAAVIFAI
                     ASFTDYLDGYLARKWHVVSNFGKFADPLADKMLVMSAFIMLVGLGLVPAWVSAVIICR
                     ELAVTGLRLLLVETGGKVLAAAMLGKIKTATQMLSIILLLCHWIFLGNVLLYIALFFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            4297..5136
                     /locus_tag="VB649_001727"
     CDS             4297..5136
                     /locus_tag="VB649_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEP1670654.1"
                     /translation="MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGS
                     GKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPK
                     IIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQV
                     ESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPIDYGYLTEKELENQLCQLI
                     SKM"
     gene            5112..5954
                     /locus_tag="VB649_001728"
     CDS             5112..5954
                     /locus_tag="VB649_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEP1670655.1"
                     /translation="MSINLQNVSYTYQAGTPFEGRALFNINLDILDGFYTAFIGHTGS
                     GKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKPIRKHVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGIL
                     AMQPKVLVLDEPTAGLDPKGRKELMIIFKKLHQSGMTIVLVTHLMDDVANYADFVYVL
                     DKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELREV
                     LKHG"
     gene            5947..6747
                     /locus_tag="VB649_001729"
     CDS             5947..6747
                     /locus_tag="VB649_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEP1670656.1"
                     /translation="MDKLILGRYIPGDSLIHRLDPRSKLLAMIIYIVIIFWANNVVTN
                     LLMLTFTLAVVFLSKIKLSFFLNGVKPMIGIILFTTLFQMFFSQGGKVIFSWWFISIT
                     DLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVESLLKPLTRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQRARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGEGRTKYRQLDWQLKDSLAIGIVSLLGLLLFFLKTSL"
BASE COUNT         2344 a         1092 c         1249 g         2308 t
ORIGIN      
        1 atattgtaga aaactatatt ttactaacac tagaatcccg acaattaagt caaaaaaagt
       61 tatcactcac ctaacctgaa taaaaatggt ataatcgtaa ggatcacact atttattaag
      121 gaaacattat gaaaattgtt cagggagtac aacttcatct gattaagacc aaacagttta
      181 aaaccaatca tattaccttt cgtttttcag gtgatttgaa ccaaaaaaca gtagcaaaaa
      241 gagtcttagt ggcacagatg ttagcaacag ctaatgagtg ttatccaact gttaggcagt
      301 ttagagaaaa attagcacga ctttatggag ctagcttgtc aactaacgtg ttaacaaaag
      361 ggttagttca tattgtggat atcgatatta cttttattca agatagatat gcttgcaatg
      421 gggaaaaaat actagatgaa atgattcagt ttttaaaaga tatcttgttc tcacccctat
      481 tatccatcgc ccagtatcag cctaaagttt ttgagactga aaaaaataat ttgattaact
      541 acatcgagtc agatagagag gattcttttt actacagctc tcttaaggta aaagaattgt
      601 tttattgtaa taagaatcta caaatgtcag aatatggtag cccagaacta attgcaaaag
      661 agactgccta tactagctat caagaatttc ataaaatgct caatgaagat cagattgata
      721 ttttcatttt aggagatttt gatgattatc gcgttgttca gctaattcat caatttccac
      781 ttgataaccg aaataaaaac ctaaatttct ttcatttaca aaattctgtc aatattatta
      841 aagaatctat tgaaaaaaga gcagttcatc aatctatttt acaattagct tatcacttcc
      901 cttcagtttt tggacaacgt gactattatg ctttagttct tttaaatggg ttgttaggct
      961 cttttgcaca ttcccgtctc tttataaaaa ttagagaaga agaaggactt gcttatagta
     1021 tagggtgtcg ttttgatagt tatacaggtt tatttgaaat ttatactgga attgacagtc
     1081 aacatcgcac taaaacgtta caactaatca tccaagaatt aaatgccatt aaaatgggac
     1141 gattctcaga acaattgatt aaaaagacca gatcgatgtt gttgaataac gccttattat
     1201 cagaagatta taataaaaat ataattgaaa gaatatacac atcttcttac attaattctt
     1261 cttattctat taaaaattgg attaaagggg ttaatgaagt taataaagca gatatcatta
     1321 aagtagctaa tcttttaaag cttcaaactg tctatttttt agaaggaata taaaatgaca
     1381 aaattagtaa agataaacta tcctaatatt gacgaagacc tttactatgt aaaattagaa
     1441 aatggtttaa ctgtttattt tataaaaaaa ataggttttt tagaaaaaac agctatgttg
     1501 acagtaggtt tcggttctct tgacaataag ttgacagtcg atgacgaatc acgagatgct
     1561 ccagcaggta ttgcacactt tttagaacat aaactctttg aagatgaatc aggtggagat
     1621 atttcattaa agtttacaca gctaggagca gagacaaatg cctttacaac tttcaaccaa
     1681 acgagtttct tcttttcaac agctagtaaa tttcaggaaa atttggaact ccttcaatat
     1741 tttgttcttt ctgctaatat aacagatgaa tctgttagta gagaaaaaaa aataatcggg
     1801 caagaaattg atatgtatca agatgatgct gactaccgtg catatagtgg aatccttcgg
     1861 aacttatttc caaaaacaag tttagctaat gatattgctg gctcaaaaga atccattcaa
     1921 aagatcacaa aaatattatt ggaaacgcat catacttatt tttaccaacc tactaatatg
     1981 agtctattca ttgtcggtga tattgatatt gacgaaactt ttttagctat tcaaaggttt
     2041 caaaccacat tatcctatcc agatagaaaa agggtaactg ttgatccttt acactactat
     2101 cctgtcatta aatcatcttc tgttgacatg gatgttacta ctgccaagct ggttgttggt
     2161 tttcgagggt atctgacctt aactcagcat tcactattaa cgtatcgtat tgccttgaag
     2221 ctatttttat caatgcttat aggttggact tctaaaatct atcatacgtt atatgaagat
     2281 ggtaaaatag acgattcatt tgatgtggat gttgaaattc atcataattt tcaatttgta
     2341 ttaatatcac ttgatacacc agagcctatc gcaatgtcta actatatccg tcaaaaatta
     2401 gccactataa agatatcaaa agagtttaca aatgagcact taaatctatt aaaaaaagaa
     2461 atgtatggtg actttattca gagtttagac tctatagaac atttaaccca tcagttcagt
     2521 ctatacctgt ctgattctga caaagaaaca tattttgata ttccaaaaat tatagaaaga
     2581 ctcactctaa aagatgttgt tacaattgga aaagcatttt ttgaaaaagc tgatgcttca
     2641 gacttcacag tcttcccaaa atagatgaaa atctgttata atagggttac tatattattt
     2701 ttgaggtacc tgtatgagtg aaaaaagtct tggtgaagtg ttaagagaat cgcgtgttgg
     2761 aaaaaatatc acactagatg atatagaatt gaagacagga atttcttccc attacttgct
     2821 ggcaatggaa ttggatcagt ttaaaattat tccggaagaa aaatttgatc aatttttaaa
     2881 agaatatgct gacattgttg agttagattt caatacttta aaaagacgat actgttatca
     2941 agttaattcc aaaaaagaca gtgatataaa atctgtaact gagattgttg aagagaagtt
     3001 aagtaagaaa cgattacaag agaagttgtt gtcacatcag agcatggggt atggtcaacc
     3061 gttagaagtt tctaaaaaca aagaaacctt agttatccct gtaaagactg ttggtttaga
     3121 tagcaaatcg ccactaaaaa cgatatcgcc tgttagccaa tttaaatcag ataacaggtt
     3181 aattcctaaa aaaaatgtgt cacgtatgag gcgaaatagc actgacagtc gttctaaaac
     3241 gtcactattt cccatagcta tattaggaac gattgctttt gcaattatca gtgttatcat
     3301 tttaggtgtt tggcaacaat tcgaaaagag tcaaagagct aaagaagctg aagttgcttt
     3361 gcttaaagcc tctgagcagt ctactaacgg tttaaaaaat aattcaaatg atcgcaaaac
     3421 tcaagtcaca actgaggggt cgggtaatta tttaatagcg actgttacta aatctaaaga
     3481 gaccgttgat atcagtgtgt ctttaaccga ggcacaaagt agttggattt ctctaacaaa
     3541 ttcagaaatt ggtgaaggtg gtataacatt gactcaagac tcgccaactt atacagcgac
     3601 tttacctgca gaaataacag aatcattgtt gacgcttggt gtgacaaatg gtgtatctgt
     3661 aacaattgat ggacaacctg ttgatctatc acctttaaca agtactgact taagttatat
     3721 cacgtttaag atccaataat taaggtagac taatgataaa aaaagaaaat attcctaatc
     3781 tattaactct tgttcgaatc gcaatgattc ctttctttct ttttattact tcctcatcta
     3841 ataaggtggg gtggcatatt tttgcagctg tgatttttgc aattgccagt tttaccgatt
     3901 atctagatgg gtatcttgcg cgtaagtggc atgtagtcag taattttgga aagtttgccg
     3961 atcctctagc agataagatg cttgtcatga gtgcctttat catgttagtt ggacttggct
     4021 tagttcctgc gtgggtatca gctgttatta tttgccgaga attggcagta actggtcttc
     4081 gattactact tgttgaaacc ggaggaaagg tccttgcagc tgctatgctg ggaaaaatca
     4141 aaacagcgac acaaatgttg tctattattt tattactttg ccattggata ttcctaggaa
     4201 acgtcttact ctatattgct ctttttttca ctatttattc tggatatgat tattttaaag
     4261 gagcaagctt tctttttaag gatacgttta aataacatgt cagctattat tgaacttaaa
     4321 aaagttacat ttaattacca taaagaccaa gaaaaaccaa cattagatgg cgtatcgttt
     4381 catgtgaaac aaggtgagtg gctgtctatc attggccata acggatctgg taaatcaacg
     4441 actattcggt taattgatgg attattggaa ccagaatcag ggtctattat tgttgatgga
     4501 gatctactaa ccataactaa tgtttgggaa attcgtcata aaattggtat ggtctttcaa
     4561 aaccctgata atcagtttgt tggagcaact gttgaagatg atgttgcttt tgggcttgaa
     4621 aataaaggta ttgcacatga agatataaaa gagagggtta atcatgcttt agagttagtc
     4681 ggcatgcaga actttaaaga aaaagaacca gcccgtttat ctggtggcca aaaacagcgc
     4741 gtagctattg caggtgcagt tgctatgaag cctaaaatta ttattttaga tgaagctact
     4801 agtatgcttg accctaaagg acgattagag ttaattaaaa ctataaaaaa catccgcgac
     4861 gactaccagc tgactgttat ttccattact catgacttag atgaagttgc tcttagtgat
     4921 agagttttag tgatgaaaga tggtcaagtg gaatcaacat caacaccaga acaattattt
     4981 gcaagagggg atgaactact ccaattaggt cttgatatcc cttttacaac atctgttgta
     5041 cagatgcttc aagaagaagg ttatcctatt gactatggat atctcacaga aaaggaatta
     5101 gaaaatcagt tatgtcaatt aatctccaaa atgtaagtta tacttatcaa gcagggactc
     5161 cttttgaagg gcgtgccctt tttaacatta atttagatat tttagatggt ttttatacgg
     5221 cttttatcgg acatactgga tccgggaaat cgaccattat gcaattgcta aatggtttac
     5281 acgttccgac aacgggaatt gtcagcgtag ataaacaaga tataacgaat cactctaaaa
     5341 ataaagagat taaacctatt cgaaaacatg taggattagt ttttcaattt ccagaaagtc
     5401 aactatttga agagacagtt ttgaaagatg ttgcttttgg ccctcaaaat tttggggtct
     5461 ctccggagga agcagaagct ttagcgcgtg aaaaactagc tcttgttggg atttcagaaa
     5521 atctttttga aaagaatcca tttgaactct cagggggtca aatgcgtcgt gttgctattg
     5581 cgggtatcct tgctatgcag ccaaaggttt tagttttaga tgaaccaact gctggtcttg
     5641 atcctaaagg gcgtaaagaa ttaatgatta tttttaaaaa gttacaccaa tctggcatga
     5701 ctattgtttt agtaacccat ctgatggatg atgtggccaa ttacgcagat tttgtatatg
     5761 tacttgacaa aggtaaaatt attttatcag gaaaaccaaa aacaattttt caacaagtca
     5821 gtttgcttga gaaaaaacag ttaggagttc ctaaggtgac taaacttgct caaaggcttg
     5881 ttgatagagg aatacctatc tcttctttgc ctattacctt agaggagcta agagaggtac
     5941 taaaacatgg ataagctgat tcttggtcgt tatattcccg gagattctct cattcatcgt
     6001 cttgacccaa gaagtaaatt attagcgatg attatttata ttgtcattat cttttgggct
     6061 aacaatgttg tgacaaattt gttgatgttg acttttactt tagcagttgt ttttttgtca
     6121 aaaatcaagt tgtctttctt tttaaatggg gttaaaccaa tgattggtat tatcctcttt
     6181 acgactttat ttcagatgtt tttctcacaa ggaggaaaag taatttttag ttggtggttc
     6241 attagcataa ctgatttagg attgagccaa gctattttaa tttttatgcg tttcgttcta
     6301 attattttct tttcaacgct gttaacgttg acgacaacac ctttaagcct atctgatgca
     6361 gttgaatcat tattaaaacc tttaacaaga tttaaagttc cagctcacga gatcggacta
     6421 atgctttctt taagtttacg ttttgtgcct actttaatgg atgataccac gcgtattatg
     6481 aatgcacaaa gggcccgtgg agttgatttt ggagagggaa atttaattca aaaagttaaa
     6541 tccattattc ctattttaat ccctcttttc gcttcaagct ttaaaagagc cgacgcatta
     6601 gctattgcta tggaagctag aggttatcag ggaggagaag ggcgaactaa atatcgtcaa
     6661 ttagactggc agctaaaaga tagtttagct attggaatag tttctttatt gggtttgcta
     6721 ctttttttct tgaaaacctc tttgtaatat tttttagcac aaaacttttc tttattataa
     6781 gaagtgaatt gtacctcaaa agttagatac aacatctaat gattgaggta cttttcttca
     6841 tttgaggaat tgaaaaccgc tatctcaact atattaatcc tcccaataat aacaaatcga
     6901 acgaaatcta aaaggactga gtcctgttca atacagaact aaattcttag tttaatgata
     6961 ttatctcgct ttttaatgtt gctaagaaga aga
//
LOCUS       DATTYN010000047         6768 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.47, whole genome shotgun sequence.
ACCESSION   DATTYN010000047 DATTYN010000000
VERSION     DATTYN010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6768
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.47"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            70..843
                     /gene="cfa"
                     /locus_tag="VB649_001730"
     CDS             70..843
                     /gene="cfa"
                     /locus_tag="VB649_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_149017463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAMP factor pore-forming toxin Cfa"
                     /protein_id="HEP1670657.1"
                     /translation="MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNNQA
                     NLQRDALVQKLDEGHQQLEAIKHEAKGTDIEATINKAIDAVDHMKSSIRFNTEMIYDF
                     SSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKA
                     QVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNR
                     LNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS"
     gene            complement(1213..2448)
                     /locus_tag="VB649_001731"
     CDS             complement(1213..2448)
                     /locus_tag="VB649_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HEP1670658.1"
                     /translation="MTQDPIANLKLARKGPIVSIIVYLSLSVAKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLI
                     HTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLAD
                     AVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLK
                     KYEKAILEIPKIVAVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQ
                     FSIYDIDIHVEPAMILEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLVDANGQ
                     TVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQHTSIWRRHESWSLLFHQ
                     ITPIAKRQLHHTHYHIVKM"
     gene            complement(2568..3890)
                     /locus_tag="VB649_001732"
     CDS             complement(2568..3890)
                     /locus_tag="VB649_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEP1670659.1"
                     /translation="MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAF
                     KLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIG
                     TFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYI
                     LSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLT
                     QSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILM
                     VGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK"
     regulatory      complement(4018..4104)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            4419..6737
                     /gene="pcrA"
                     /locus_tag="VB649_001733"
     CDS             4419..6737
                     /gene="pcrA"
                     /locus_tag="VB649_001733"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEP1670660.1"
                     /translation="MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKFVNPWNILAITFTNKAAREMKERALALNPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQA
                     ADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVL
                     LEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVAST
                     ISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIA
                     YLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKG
                     KAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIE
                     EFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLF
                     GKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQAR
                     KAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLE
                     VSGSGKTMELKIKFPEVGLKKLLASVAPIEKK"
BASE COUNT         2267 a         1265 c         1328 g         1908 t
ORIGIN      
        1 aagcgcttat aaattaattt aacttcactt aactatttaa ataggtttat tatattcagg
       61 aggaataata tgaaacccaa acaccttctc tgtctttcaa cagttgttgc tggattagct
      121 ttattttcaa ctatgacgca ctcagtttta gctgatgatg cttcaaatcc cgatactatt
      181 ttaatgaata acaaccaagc gaatcttcaa agagatgctc tagtgcaaaa gcttgatgag
      241 ggacatcaac aattagaagc tattaaacat gaagctaaag gtactgatat tgaggctact
      301 attaacaaag ctatcgatgc tgttgatcac atgaagagtt ctatacgctt caatactgaa
      361 atgatctatg attttagttc aattggggca agagtagaag cattatcaga tgctatcaaa
      421 gcaatcgtat tttccacaac ccaattaact cataaagtag aaaaagcgca tactgatatg
      481 gggtttgcta ttactaaatt agtcattcgt attatagatc catttgcatc tgttgacgct
      541 atcaaagctc aagtacaaga aattaaagca cttgaggaaa aagttatcaa ttatcctgat
      601 ttacagccaa cagaccgtgc tactatctat actaaagcta aactaaataa agctatttgg
      661 aacactcgtt tagaaagaga taaaaaggtt ttaggtatca aaccatttga tgtttacaat
      721 agacttaaca aagctatcac acatgcggtt ggtgtccaac taaatccgac aaccactgtt
      781 caacaagttg acgatgaagt tattgctgtg caaaatgctt tggaaacagc tcttaagtca
      841 tagagtgtat aagtaatgtg ttgtataggt agatgattat attaggatat agaataggta
      901 aatattttaa atatcttacc attgtagagt ttgaggtgat gttctcataa acaatgagtc
      961 acctgtagcc ctttttgcct ttaacatgat gtaccaattt aaggtattgt tcaaccgtca
     1021 ctattgaatc ttgtttaacc tcctaaacta ataagattca atatgaaaac gtgtattctt
     1081 aaaaaaatcc ctatgatctg tttaaaaaca aattgtaggg atttttttaa ctatttaact
     1141 tattattttg ggactaggaa tcgctttagg aatatcatga agtatagtta tgttataaga
     1201 taagtaatgt ttttacattt ttacaatatg atagtgtgtg tgatgtaatt gtctcttagc
     1261 gataggggta atttggtgga agagtaagga ccaagattca tgacgtctcc aaatactggt
     1321 atgttgattg ccatttaatt ggtaagttac caacatcgtt ttttgactaa tggattcaat
     1381 ctgaaaatgg ttgaagttac ttggataata aatttcttgg ttcaaaaatt gttcatagtt
     1441 aactgtttgg ccattcgcat caaccagttg gaaagactta gcaatgtagt ggtcatagtc
     1501 aggaacctta ctcaaaatta atttttcgta gcggtagagc tttttggcga cattatcaaa
     1561 aatctcttct tcgagaatca tggcaggttc aacgtgaatg tcaatgtcat aaatagaaaa
     1621 ttggtcactc aataactgct ccactttctc tgtaatagag tgactttcat agactgaaag
     1681 atcaggattc atttcaagta caatatcaag atagacattg ctaccatagg tcctagctcg
     1741 ttgagactta acggcgacaa ttttagggat ttctaaaatg gctttttcgt attttttcaa
     1801 atgacggcta tcaaatccat cagataaact aaacgaactt tccataaaga tatcaaaagc
     1861 tgttttaaga ataaagaacg taatgatcat agcagctata tgatcgataa ctggtaaatg
     1921 caaagaagct gctataatag caattgatgt tccgatagaa gtaacagcat cagctagatt
     1981 atccttagaa gcagcgacta aggcactgga ttttacacgt ttggaaagac gtttgttaaa
     2041 gacataaacc cctaacataa caaaagctga aacgataccg acaatagctc caagagggtc
     2101 aatatcaact tgctgaccac taaagatact tttaattgtg tgaatcagta cttggaaacc
     2161 tacaagaaac ataataaaag aagtgacaag gctggataag tcttcaattt tccaatgacc
     2221 aaatttatga ttggcatcgg ctggttggct agctaagtga agaccaataa gcagggctac
     2281 atttcccaca atatccgata aattgttaaa tccatcagca ataagggaac ttgcatttaa
     2341 caaataacca gctaataatt tggcaacact aagcgacaag tagacaataa tactaacgat
     2401 tgggcccttt ctggctagtt ttaaatttgc aatcggatcc tgtgtcataa taactccttt
     2461 gatttcaact ttatattata ccataaaaag gggcttaaga aaaaagccta gcgtcttgaa
     2521 cttggcagaa gaagactagg tataactggg tagtactaac gtcatgttta cttaataaag
     2581 taatgcttgg tttctaaaat aacaactggc gagagagcta ggagggcaat caggttagga
     2641 agtgccatta aaccattgac aatatcagcc aaaacccaaa ttagttctaa cttaaggaag
     2701 cctcctaggc ctaccattaa gataaagaca atacggaagt aggtgagatg tgtaatgcca
     2761 aagaggaatt caaagcagcg ttctccataa taactccatc ctaaaatcgt tgtaaaggcg
     2821 aagagaacta gggaaaaggt taggccaaaa gtccctaaat ttccaaacac agtggcaaag
     2881 gcagattggg tcagaggagc cccttcgagc tgcccagtcc attggcctgt tactaaaata
     2941 gataggccgg ttagggtaca gataataatc gtatcaataa aagttcctgt catggagatc
     3001 agtccctgct ccacgggttc attggtttta gctgctgctg cagcaatagg tgcagatcct
     3061 agtccagact cattggagaa gacaccacgt gcaattcctt tttgaatggc atccttcatg
     3121 agacttccag caaagcctcc aatagcagct gtcggagtga aggctgattg aaagactaaa
     3181 cgaataacag gaagtagctg ttggtagtga ctaaaaataa ctgctaaact agatagaata
     3241 taaaaaatag ccataaaagg aacgactttt tcagccactt tggaaatgga atgaatgcca
     3301 ccaaaaataa tggcagccac aaagatagct aaaacaatac tgaccatttg tggggataag
     3361 ccaaagctat gacctaaaga cgaggtgatc gagttcactt gagcaaaggt tcctattcca
     3421 aatagggcaa ctaggatccc tgaacccgca aaaagaatgg ctaagggttt ccattttgtc
     3481 cccatgccat taacaatata gtacatagga ccaccagaaa tatgaccgtt ggcatccttt
     3541 gtacggtatt taatcgctag taccccttca gcgtacttag tggccattcc aaaaaaagcg
     3601 gcaacccaca tccaaaagag cgctccagga ccaccagact tgatagcagt ggcaacccca
     3661 acaatgttac cagttccgac agtagcggca agggcagttg caagagcagc aaaggatgaa
     3721 atatctccat gtccttcgtc atctgaaaaa atgagtttaa aggctcttgg tagttttaag
     3781 atttgaatta atcctaaacg actggtaagg taaatccccg tcccaaccaa taaaattaag
     3841 aggggcggtc cccaaacaag gttatcaatt aatttaacga gtgctatcat ctttctctcc
     3901 taaaagtcat cgaagacgcc aaaagaaaaa agctatctct ttctttgaga caacttctga
     3961 agcaatgata aaacagcaaa cacaaaaaag actaagactg ttcttaatgg tgtttgtatt
     4021 ttaccttctg tccttttgcc tgagagattg agcagtatgc cttgcccctt cggcgcctaa
     4081 taaggtctct ccagaagtcc gtccatcaaa cagtcccgtt caaaaactga acacctgaga
     4141 gtataactcc ttcggcgaaa aaaattcttc tcctgcatga catcattcgg tttattaaat
     4201 taggactatc ataccttaaa aaacgaatga agtcaaccaa aatagcaaaa aaataaggaa
     4261 tgctttaaga aatcgctatt atttttaaat atctgatcct aaactagaaa aaaggaatct
     4321 ctttactttt ggggtcttct ttgctatttt tcttggaaac atgatataat tttaaggttg
     4381 ataaaagaga tgtcactgaa cgagattaag gagaaagcat gaatccttta ttaaatggaa
     4441 tgaatgatcg gcaggcacaa gctgttcaaa caactgaagg ccccttattg attatggcgg
     4501 gggctggttc tggtaaaaca agggtactga cccatcgtat tgcctattta attgatgaaa
     4561 aatttgtcaa tccttggaat attttagcta ttacctttac taataaggct gcgcgtgaaa
     4621 tgaaagaaag ggccttggcc ttaaatccag ctactaaaga taccttaatt gctacctttc
     4681 actccatgtg tgtacggatt ctgcgtcgtg aggctgatca cattggttac aaccgaaact
     4741 tcacaatcgt ggatccaggt gagcaacgaa cgttgatgaa gcgcatttta aaacaattaa
     4801 atatagaccc taaaaagtgg aatgaacgtt ctattttagg aactatttca aacgctaaaa
     4861 atgatttgct tgatgaaaag ggatacgagg cacaggctgc tgatatgtat agtcaaatcg
     4921 tagcgaggtg ttacaaagct tatcaggaag aattacgacg tagcgaagca cttgactttg
     4981 atgatttaat catgatgacg ctacgcctgt ttgacgctaa tcctgacgtg ttagcttatt
     5041 accagcagcg ttaccaatac attcatgtgg atgagtacca agataccaac catgctcaat
     5101 atcagctaat taaattacta gcttctcgct ttaaaaatat ttgcgttgtt ggagacgctg
     5161 atcagtctat ctatggttgg cggggagctg acatgcaaaa tattcttgat tttgaaaaag
     5221 attacccaga tgctaaggta gtgcttttag aagaaaacta tcgctctacc aagaaaattc
     5281 tgcaagcagc taacgacgtg attaacaata accgtaatcg ccgtcctaag aaactttgga
     5341 cacaaaatgc ggatggtgaa caactggttt attaccgggc aaatgatgag cgagatgagg
     5401 cagtatttgt ggcctcaacc attagcaata tgagtcaaga gcttggaaaa aacttcaaag
     5461 atttcgctgt tttataccgt accaatgccc aatctcggac cattgaagaa gcactcttaa
     5521 aatccaatat tccttacacc atggttggag gcaccaagtt ttacagccgt aaagaaattc
     5581 gggatttgat tgcctattta accattgttg ctaaccctgc tgataatatt tcttttgagc
     5641 ggattgtgaa tgagcctaaa cgaggtgttg gtccaggaac gcttgataaa ctgcgtcagt
     5701 ttgcctatga gagtgaccag tctttattag aagcagcttc aaatctattg atgtccccct
     5761 tgaaaggtaa agcagcacaa gctatcatgg acttggccaa tattctcggt cagctacgtc
     5821 aagacctaga tcagatgagt atcaccgact tagcagaagc tttgttagaa aaaacaggct
     5881 atttagatag cttacgcctg caaaatacat tggaaagcca agcccgtatc gaaaatatcg
     5941 aagaattctt atctgttacc aaaaattttg acgagtcaag tgcctctcaa gaagaagacg
     6001 aaaccggtgt tgatcgcttg ggacgttttt taaacgattt agcactgatt gctgatacag
     6061 atgattccca agcagaagct gctgaagtaa ccttaatgac cctacatgct gccaaaggct
     6121 tggagttccc tgttgttttc ttaattggta tggaagaagg tgtcttcccc ttatcacgtg
     6181 cctctgaaga tccagatgaa ttggaagaag aaagacgttt agcttatgtc ggaatcacaa
     6241 gagctgaaga agttctcttt atgaccaatg ccaacaccag aaccctcttt ggtaaaagta
     6301 gttataaccg tccaacacgc ttcttgaaag aaatttcaga ggaactactc tcttataaag
     6361 gattggcaag accagcacaa tcttcatttg gtgtgcgttt ttctactgaa acacacacac
     6421 agtttggaca agggatgagc ctatcagaag ccttacaagc tcgaaaggcc caggctcaag
     6481 taagacaatc agcacagcca atgcaggcac atacgatacc atcagcttca actagctcag
     6541 ttttaccgtt tggttctaat agctctgtag aagaggtcac ttggcagatt ggcgatatcg
     6601 ctcaccataa aaaatgggga gacgggactg tgcttgaggt ttcaggctcc ggaaaaacga
     6661 tggaattgaa aatcaaattt ccagaagttg gtttaaagaa attactagca agtgttgctc
     6721 ctattgagaa aaaataagaa aaaaatgagc ttcctactat ataagtga
//
LOCUS       DATTYN010000048         6670 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.48, whole genome shotgun sequence.
ACCESSION   DATTYN010000048 DATTYN010000000
VERSION     DATTYN010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6670
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.48"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(20..1477)
                     /locus_tag="VB649_001734"
     CDS             complement(20..1477)
                     /locus_tag="VB649_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEP1670661.1"
                     /translation="MAEKRKVAVYCRVSSMHQAIEGYSIEQQRDSLTKYCEAMEWNIY
                     DIYIDAGFSGGKLERPAMDKLIREAEAGKFDTVAVYKLDRLSRSVQDTLHLIRDVFKE
                     HDIDFVCLQENIDTKSAMGNLFLTLLSAIAEFEREQITERMAMGRHGRAKSGKSMMWA
                     RPAYGYRYDRESQTVSVVQSEAMIVKRIYKEYLEGKSVSQIKNDLNSEGHITKEKPWV
                     YKRITYILQSRVYTGVNEYKGEIYDGKHEAIIDTETFELTQMEFAKRQQQTKDKKNNP
                     RPFQAKYMLSGLARCGYCKAPLKLRLGAVRKDGTRAMVYDCHNRWNRKVTYLTIYNDN
                     KQCTESGRYQKADLEAYVLDKIKELQLNPDTIREKMDLNEKPTANTEEIKKQIAKTNQ
                     QIDKLNDLYLNDLITVEKLKERANKLKKERELLEAELSKNSDHLFKAKKKQLNDLLMN
                     KDIDSMTYEEQRNLVKMLIYKVDVTKEDINIIFDF"
     gene            complement(1609..2127)
                     /locus_tag="VB649_001735"
     CDS             complement(1609..2127)
                     /locus_tag="VB649_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HEP1670662.1"
                     /translation="MAKVIFQDNFLLMGTNYHEKEANKVMAEIGKKSPYWDKDKDFIS
                     DYIKSNFKDIYKYYRVSTKDVEIVREPLNRHDPNAIKVMVNKTFVGYFPADLAKRLTP
                     YVKKSSHYQMEATLTGRGGQYKTLKNDLKTVVTKKKNITYKLRLTILKVDRVSKSKNA
                     GLLESIASWFLN"
     gene            complement(2139..2894)
                     /locus_tag="VB649_001736"
     CDS             complement(2139..2894)
                     /locus_tag="VB649_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670663.1"
                     /translation="MEQLGDRVRKLREGRNMTQTELSEILGMKTYTTVSKWEKNENFP
                     KGKDLKKLAEIFNVTSDYLLGLTDSKLGKITIQNEQPEIVSIYNQLEQPRQEKVLNFA
                     NEQLEEQNKTVSIFDKKSEETEDYITDYVEGLVAAGLGAYQEDNLHMEVKLRADDVPN
                     EYDTIAKVAGDSMKPLIQDNDLLFIKVSSQVDMNDIGIFQVNGKNFVKKLKRDYDGAW
                     YLQSLNKSYEEIYLSKDDDIRTIGEVVDIYREY"
     gene            3096..3308
                     /locus_tag="VB649_001737"
     CDS             3096..3308
                     /locus_tag="VB649_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670664.1"
                     /translation="MVTIAELRAKHNKMSQRELAKELGVTQTSISNWEKDQTKISGEY
                     LISLALFFDVSTDDILGINKQATQKF"
     gene            complement(3477..3659)
                     /locus_tag="VB649_001738"
     CDS             complement(3477..3659)
                     /locus_tag="VB649_001738"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670665.1"
                     /translation="MAKDLLEVTSEIIIGNHESFYREFRAAKNEGKIKDATFAEYLGL
                     EYKKLYQYVSNVNSID"
     gene            3892..4077
                     /locus_tag="VB649_001739"
     CDS             3892..4077
                     /locus_tag="VB649_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670666.1"
                     /translation="MNKLELFLLATTVILAIITRLQHEVIKKHNSPENKRKIFREVAL
                     ENSKGWSEKRSRGEVVS"
     gene            4611..5000
                     /locus_tag="VB649_001740"
     CDS             4611..5000
                     /locus_tag="VB649_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEP1670667.1"
                     /translation="MTKKELFENFQKNWMRLLSPFEIEDIDKWIDEDNMPIEVVNEAL
                     KETILYNAPNLRYLNRVLNNWKRQGIDTVEKVEFSRLQFENKKLSQNKNQQSNVPSWS
                     NPDYKEPDLKEFALGSMDGIEDGSGDF"
     gene            4981..5214
                     /locus_tag="VB649_001741"
     CDS             4981..5214
                     /locus_tag="VB649_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670668.1"
                     /translation="MDQEIFNFFNKQIKKDFGKTASKETFAKFASYCAEGIEKNGVKP
                     IFNWINLYAFGTGMTTAEADRLRIERYKQENAL"
     gene            5211..5351
                     /locus_tag="VB649_001742"
     CDS             5211..5351
                     /locus_tag="VB649_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670669.1"
                     /translation="MTKQHRETLIWYRASHQERERLLDFGLVDKARYVTLLRQLRKKY
                     AI"
     gene            5360..5566
                     /locus_tag="VB649_001743"
     CDS             5360..5566
                     /locus_tag="VB649_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670670.1"
                     /translation="MTPEEAEKAKIRAKQELETFSIYLDQAIDDLGGVLTSREVFLAA
                     GITYLGAGQTDIHAAVEGLCEQIQ"
     gene            5622..5951
                     /locus_tag="VB649_001744"
     CDS             5622..5951
                     /locus_tag="VB649_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670671.1"
                     /translation="MNIKEKIVVLRNTEDGSFLKSFKNKKDVLAYNVELTDSIQLASF
                     LPEEFYNMQKDKIDNLAETFGYDVVVIEASYDLKFIDGEDVPELTKEQKVKSMVNGMF
                     EQVFGGE"
     gene            5954..>6670
                     /locus_tag="VB649_001745"
     CDS             5954..>6670
                     /locus_tag="VB649_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014334626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEP1670672.1"
                     /translation="MATTELTELTQKQVTSNVANRIEAMKSEGLLIAPNYSVSNALSS
                     AYYALKNSNSGNLLEKCTHESIYNALLDMVTQGLSPAKTQCYFIPYGNSVKLNRSYFG
                     TMKVVKQLSEVKDIYVKVIYEGDDFQAENTETGWKFVKHDSNWKNQDNPIEGAYCIIK
                     KNDGEEVMTIMTKKEIDKSWGQSRNGSVQKNFPQEMAKRTVINRAAKQFFNTSDDNDL
                     FVDAVNRTTENEYDNDRQVKD"
BASE COUNT         2180 a         1204 c         1226 g         2060 t
ORIGIN      
        1 atgcaagaca ctaaaaacgc taaaaatcaa aaataatatt gatgtcttct ttcgtgacat
       61 ctactttgta tataagcatt ttgacaaggt ttcgctgctc ttcataagtc atactatcaa
      121 tatctttgtt catcaataag tcattcagct gtttcttttt tgctttgaac aagtggtctg
      181 agttcttgct gagttcagct tctagcagct cacgctcctt ctttaatttg ttagcacgtt
      241 ccttgagttt ttcaacagtt atcaggtcat ttaggtatag gtcattcaac ttgtcaattt
      301 gttggtttgt tttcgcaatt tgttttttga tttcttcagt gttggcagta ggtttttcgt
      361 tgaggtccat cttttctctg attgtgtctg ggttgagctg taactctttt attttgtcta
      421 acacataagc ttctagatct gctttttgat accgtcctga ctcggtacat tgtttattgt
      481 cattgtatat ggttaaatat gtaactttcc tattccagcg attgtggcag tcatacacca
      541 ttgctcttgt tccgtctttt ctgacagctc caagtcttaa tttgagagga gctttgcagt
      601 agccacatct ggcaagacct gacaacatat attttgcctg aaaaggtcgt ggattgtttt
      661 tcttatcttt cgtttgttgt tgcctttttg cgaactccat ctgagtcaat tcgaatgttt
      721 ccgtatcaat gatagcttca tgttttccat catatatttc ccctttgtac tcatttactc
      781 cggtgtacac tcttgactga agtatatagg ttattcgctt atagacccac ggcttttcct
      841 ttgtgatatg cccttcacta ttcagatcat tcttgatttg ggaaaccgat ttcccctcaa
      901 gatactcttt gtatattctc ttgacaatca ttgcttcaga ttggactaca gaaacagtct
      961 ggctttctct atcgtatctg taaccatagg ctggtcttgc ccacatcatg gactttcctg
     1021 attttgctct tccatgtctt cccattgcca ttcgctcagt tatttgctca cgttcaaatt
     1081 cagcaatagc agaaagcagc gtcaagaata aattgcccat ggctgactta gtgtcgatat
     1141 tttcttgaag gcaaacaaaa tcaatgtcat gttctttgaa cacatcccta atcaagtgaa
     1201 gagtgtcctg aacgcttcta gagagtcggt caagcttata tactgccaca gtgtcgaact
     1261 tcccagcttc agcttctctg ataagtttat ccatagctgg gcgttctaac ttaccaccac
     1321 tgaaaccagc atcaatgtat atgtcgtaga tattccattc catagcttca cagtattttg
     1381 tcaaactgtc tcgttgttgt tcgattgaat aaccttctat tgcctggtgc atggatgaaa
     1441 ccctgcaata tacggctact tttctttttt cagccatgct gcacctcttt tcttatttcc
     1501 taaaaaatga taaaatgggt acaagaaaaa gggcctttta atgcctgatt tcttgtacta
     1561 gattcgcctc acgctctcct cgccaaaatt gagcgtgggg cttttttgtt agttgagaaa
     1621 ccaagatgct atcgactcta ataatccagc atttttactt tttgatactc tatctacttt
     1681 taaaatagtc aatcgtaact tataagttat atttttcttt ttagtaacca cggtctttaa
     1741 atcgtttttg agtgttttgt attgtccacc acgaccagta agcgttgctt ccatttggta
     1801 atgactagat ttttttacat aaggggttaa tcgtttagct aagtctgctg gaaagtagcc
     1861 aacaaaagtt ttgtttacca tgacttttat ggcatttgga tcgtgacgat taagaggttc
     1921 tctgacaatc tctacatctt ttgttgagac cctgtaatac ttgtagatat ccttgaagtt
     1981 tgattttatg tagtcagaaa taaaatcttt atccttatcc cagtatggtg atttcttacc
     2041 aatttcagcc ataactttat tagcttcttt ttcatgataa tttgttccca ttaagagaaa
     2101 gttatcttgg aatatgactt ttgccataac agcctccttt aatattccct ataaatatcc
     2161 acaacttcac cgattgtgcg gatgtcgtca tcctttgaaa gatagatttc ctcatagctt
     2221 ttatttaagc tttgcaagta ccaagcgcca tcataatcac gcttgagttt ttttacaaag
     2281 tttttaccat tgacttggaa tatccctata tcattcatat cgacttggct agataccttg
     2341 atgaatagca aatcgttgtc ttgaataagt ggtttcattg aatcgccagc tacttttgca
     2401 atagtatcat actcattggg gacatcatca gcacgtagtt taacttccat atgtaaattg
     2461 tcttcttggt atgccccaag accagcggca accaatccct caacgtagtc agtgatataa
     2521 tcttctgtct cctcagattt tttatcgaat atagaaacgg ttttattttg ttcttctaat
     2581 tgttcgttag cgaagttgag gactttttct tgtctaggtt gttctagttg gttgtagata
     2641 gaaacgattt caggttgttc gttctgtatt gtgattttcc caagtttact atctgtgagt
     2701 cctaaaagat agtcagaggt aacgttgaaa atctctgcta gtttttttag gtctttacct
     2761 tttggaaaat tttcattctt ctcccacttt gaaacagtag tataggtttt catgcccaat
     2821 atttctgaaa gttcagtctg agtcatgttg cgcccttctc tcaactttct tactcggtcc
     2881 cctaattgct ccataggata cctccttttt aattttgata agtaaattat atcaaaacta
     2941 tgattataaa tcaactatat aagaaaaaag ttttaaataa actatatgat ttacgatttt
     3001 tttaaaaaaa cagaaaataa atcatataaa acacttgaca caagatttaa aatcatatag
     3061 aatgtaatca tcatcaagaa aggagcgact cagctatggt aactattgca gaattaagag
     3121 ctaaacataa taagatgtca cagcgtgaat tagcaaaaga attaggtgtt actcaaacat
     3181 ctatcagcaa ctgggaaaaa gaccagacaa agatttcagg tgagtatctt attagtctag
     3241 ctttgttttt cgatgtatct accgatgaca ttcttgggat aaacaagcaa gcaacacaaa
     3301 aattttaaac actatatgat tttaaatcat atagtagaaa ggacacatat gaacgaaata
     3361 acatttaccc tatattgcac aacatctgaa gaagcaatca cggaagtaaa gaaactaaaa
     3421 gaagcccatc caaaggatag acttcaattt aatgtaaaca ttaagtctga gttttactag
     3481 tcaatagaat tgacgttaga aacgtattga taaagtttct tatactcaag acctaagtat
     3541 tccgcaaaag tagcatcctt aattttacct tcgttttttg cagctctaaa ttcacgataa
     3601 aaactttcgt gatttccgat gataatttct gatgttactt ccaacaaatc tttagccata
     3661 taatcacctc ccttcgagat gattataaca aaaaagtccg acggcaatcg gactctgaac
     3721 aaaaatatta caaaggaatt ataccatgaa acgacaaaaa ggacaatggc agccaagggt
     3781 caattgcttc ctgaaggata tgaccccagt ttcccccagt aacatatctg taccagataa
     3841 tcacccagtt tacagattac taactaaaat caaccaagaa aggctctctg catgaacaaa
     3901 ctagaattat ttttattagc aacaaccgtc atcttagcaa tcattactag gcttcaacac
     3961 gaagtcatta aaaaacataa ttcacccgag aataagcgaa aaatttttag ggaagtggct
     4021 ttagaaaaca gtaaagggtg gagcgagaag cgctctagag gagaggtggt cagctgatgc
     4081 agtacatttt tcaagacatt aacaggtagt tacacagctg ttagcaatga atttattcag
     4141 gacaaagaac tttttaataa ggaaaaagga ctgctgctaa ccattttgag taatgcagac
     4201 gagtggagag tctatcctga agagctcgct agacgttgta aggatagcga atctgcaatc
     4261 agaagccagt tgaaagcgtt agagaatgcc aagtatatca gaacttatag aaaatcattt
     4321 ggcgggcgat atggtaccga aacctataga ttctgttctg acagaaaaat aagcgacgag
     4381 gcgttcaata ctttgaaggc agaacaggac ttagaactag aaaaaattgc taatacctaa
     4441 tttgctaatg tgcaatttgc taatgtgcaa tttgctaatg tgcaatttgc taatgtgcaa
     4501 tttgctaatc aacaaattag ccaactaata aatactaaca ttaaataaat actaaataac
     4561 aataaatact aacagataat aagctactgc tgctagaagg gagtcgataa atgactaaaa
     4621 aagaactttt tgaaaatttt cagaagaatt ggatgaggct tctttcgccg tttgaaatag
     4681 aggatatcga taaatggata gatgaagaca atatgcctat agaagttgtt aatgaagcgt
     4741 tgaaagaaac gattctatac aacgcaccga acctcagata tttaaacaga gtcctaaata
     4801 actggaaacg acaagggatt gatacagtcg agaaagtcga attttctagg ttgcaatttg
     4861 aaaataaaaa gctcagtcaa aataaaaatc aacaatccaa cgtcccaagc tggtcgaatc
     4921 cagactacaa agaaccagat ttaaaagaat ttgctctagg aagcatggac ggtatagaag
     4981 atggatcagg agatttttaa tttttttaac aaacaaatca aaaaagattt tggtaaaacg
     5041 gcgagtaaag agacttttgc taagtttgct agttactgcg ccgaaggaat cgaaaaaaat
     5101 ggagttaagc caatttttaa ttggataaac ctatacgctt ttggaactgg tatgacaaca
     5161 gcagaagcag accggttgag aatagagcga tataaacagg agaatgcgtt atgacaaaac
     5221 aacatagaga aacgcttatc tggtaccgag caagtcatca agagcgtgag agattgcttg
     5281 attttggact agttgataaa gcacggtacg tgacactatt gcggcaattg cgtaagaaat
     5341 atgcgattta ggaggaaata tgacaccaga agaagcagaa aaagcaaaaa tcagagctaa
     5401 acaagaactt gaaacgttta gcatatacct tgatcaggca attgatgatc tcggtggagt
     5461 tctaacttca cgagaagtct ttttagcagc gggaataaca tatcttggcg caggtcagac
     5521 agatatacat gctgcagtcg agggattatg tgagcaaatc caatgatttt aaatttagtg
     5581 aagactggga gagcaactaa aacacaaaaa gaggaaatga aatgaacatc aaagaaaaaa
     5641 ttgtagtgct aagaaacact gaagacggaa gttttttaaa gagtttcaaa aacaaaaaag
     5701 atgtacttgc ttataatgtg gaacttacag atagcattca gctggcatca tttctaccag
     5761 aagaatttta caacatgcaa aaagataaaa tcgataattt agccgaaacg tttggatatg
     5821 atgttgtagt tatcgaagca tcatatgacc taaaatttat tgatggcgag gatgttccag
     5881 agttaacaaa agagcaaaaa gttaaaagta tggtaaacgg aatgtttgag caggtttttg
     5941 gaggtgaata gagatggcaa caacagaatt aacagaatta acgcaaaagc aagtaacttc
     6001 aaacgtggca aaccgtattg aagccatgaa aagcgaaggc ttgctgatcg caccaaatta
     6061 cagtgtaagc aatgcactaa gttctgctta ctacgccttg aaaaactcaa atagcgggaa
     6121 cttgcttgaa aaatgcacgc acgaaagcat ttataacgct ttgcttgaca tggtaactca
     6181 gggactaagc ccagcgaaga cacagtgcta cttcattcct tacggaaatt ccgttaagct
     6241 taatcgctca tacttcggaa ccatgaaagt tgtaaagcaa ctgtcagaag taaaagacat
     6301 ttacgtaaag gttatttacg agggggacga tttccaagca gagaatacag aaactggatg
     6361 gaaatttgtt aagcatgatt ccaactggaa aaaccaagac aatccaatcg agggagctta
     6421 ttgcatcatc aaaaaaaacg atggagaaga ggtcatgact attatgacca aaaaagaaat
     6481 cgataaatct tgggggcagt caagaaatgg tagcgtacaa aagaatttcc ctcaagaaat
     6541 ggcaaaacgg acagtcatta atcgggcagc taaacaattc tttaatacga gtgatgacaa
     6601 tgatttgttt gtagatgcgg taaaccgtac cacagaaaac gaatatgaca acgacagaca
     6661 agtcaaagat
//
LOCUS       DATTYN010000049         6371 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.49, whole genome shotgun sequence.
ACCESSION   DATTYN010000049 DATTYN010000000
VERSION     DATTYN010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6371
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.49"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            10..1197
                     /gene="hasA"
                     /locus_tag="VB649_001746"
     CDS             10..1197
                     /gene="hasA"
                     /locus_tag="VB649_001746"
                     /EC_number="2.4.1.212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronan synthase HasA"
                     /protein_id="HEP1670673.1"
                     /translation="MYLFGTSTVGIYGVILITYLVIKLGLSFLYEPFKGNPHDYKVAA
                     VIPSYNEDAESLLETLKSVLAQTYPLSEIYIVDDGSSNTDAIQLIEEYVNREVDICRN
                     VIVHRSLVNKGKRHAQAWAFERSDADVFLTVDSDTYIYPNALEELLKSFNDETVYAAT
                     GHLNARNRQTNLLTRLTDIRYDNAFGVERAAQSLTGNILVCSGPLSIYRREVIIPNLE
                     RYKNQTFLGLPVSIGDDRCLTNYAIDLGRTVYQSTARCDTDVPFQLKSYLKQQNRWNK
                     SFFRESIISVKKILSNPIVALWTIFEVVMFMMLIVAIGNLLFNQAIQLDLIKLFAFLS
                     IIFIVALCRNVHYMIKHPASFLLSPLYGILHLFVLQPLKLYSLCTIKNTEWGTRKKVT
                     IFK"
     gene            1233..2441
                     /gene="hasB"
                     /locus_tag="VB649_001747"
     CDS             1233..2441
                     /gene="hasB"
                     /locus_tag="VB649_001747"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase HasB"
                     /protein_id="HEP1670674.1"
                     /translation="MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSP
                     IQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIK
                     EVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYF
                     NELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIP
                     QTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDV
                     IDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNK
                     VYSRDIFNRD"
     gene            2623..3537
                     /gene="hasC"
                     /locus_tag="VB649_001748"
     CDS             2623..3537
                     /gene="hasC"
                     /locus_tag="VB649_001748"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     HasC"
                     /protein_id="HEP1670675.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
                     AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIF
                     DILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEH
                     PEVKEDLKNYIIKLGKALEKSKVPTHSK"
     gene            3845..4258
                     /gene="yaaA"
                     /locus_tag="VB649_001749"
     CDS             3845..4258
                     /gene="yaaA"
                     /locus_tag="VB649_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEP1670676.1"
                     /translation="MIYKLFTEFITLQALLKELGIIQSGGAIKGFLAETTVLFNGEDE
                     KRRGKKIRVGDKISLPDQDLIITIVEPSQEEKEQFAEEMAEKTRVAALVKQMNQANKK
                     TSSKHNNRQSTTKKSLRATKKTKGKPTAPVRFPGI"
     gene            4260..5366
                     /gene="recF"
                     /locus_tag="VB649_001750"
     CDS             4260..5366
                     /gene="recF"
                     /locus_tag="VB649_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEP1670677.1"
                     /translation="MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIY
                     FLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQA
                     KLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQR
                     NSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESL
                     SLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFA
                     SQGQHRSLILSLKIAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQT
                     FITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH"
     gene            complement(5422..6285)
                     /locus_tag="VB649_001751"
     CDS             complement(5422..6285)
                     /locus_tag="VB649_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEP1670678.1"
                     /translation="MEGIFYALIPMFTWGSIGFVSNKIGGKPSQQTLGMTFGALLFSL
                     AVWLIVRPEMTLQLWIFGILGGFIWSIGQTGQFHAMQYTGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTRPMQFVVGSLALLLLIIGFYFSSKQDDANAQVNHLHNFSKGFRALTYS
                     TIGYVMYAVLFNNIMKFEVLSVILPMAVGMVLGAITFMSFKISIDQYVIKNSVVGLLW
                     GIGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVVTGIICFI
                     VGAMLLGVVKS"
BASE COUNT         2214 a         1133 c         1089 g         1935 t
ORIGIN      
        1 tatctaaata tgtatctatt tggaacatca actgtaggaa tttatggagt aatattaata
       61 acctatctag ttattaaact tggattatct ttcctttatg agccatttaa aggaaatcca
      121 catgactata aagttgctgc tgtaattcct tcttataatg aagatgccga gtcattatta
      181 gaaactctta aaagtgtgtt agcacagacc tatccgttat cagaaattta tattgttgat
      241 gatgggagtt caaacacaga tgcaatacaa ttaattgaag agtatgtaaa tagagaagtg
      301 gatatttgtc gaaacgttat cgttcaccgt tcccttgtca ataaaggaaa acgccatgct
      361 caagcgtggg catttgaaag atctgacgct gacgtttttt taaccgtaga ttcagatact
      421 tatatctatc caaatgcctt agaagaactc ctaaaaagct tcaatgatga gacagtttat
      481 gctgcaacag gacatttgaa tgctagaaac agacaaacta atctattaac gcgacttaca
      541 gatatccgtt acgataatgc ctttggggtg gagcgtgctg ctcaatcatt aacaggtaat
      601 attttagttt gctcaggacc attgagtatt tatcgacgtg aagtgattat tcctaactta
      661 gagcgctata aaaatcaaac attcctaggt ttacctgtta gcattgggga tgatcgatgt
      721 ttaacaaatt atgctattga tttaggacgc actgtctacc aatcaacagc tagatgtgat
      781 actgatgtac ctttccaatt aaaaagttat ttaaagcaac aaaatcgatg gaataaatct
      841 ttttttagag aatctattat ttctgttaaa aaaattcttt ctaatcccat cgttgcctta
      901 tggactattt tcgaagtcgt tatgtttatg atgttgattg tcgcaattgg gaatcttttg
      961 tttaatcaag ctattcaatt agaccttatt aaactttttg cctttttatc catcatcttt
     1021 atcgttgctt tatgtcgtaa tgttcattat atgatcaaac atcctgctag ttttttgtta
     1081 tctcctctgt atggaatatt acacttgttt gtcttacagc ccctaaaact ttattcttta
     1141 tgcaccatta aaaatacgga atggggaaca cgtaaaaagg tcactatttt taaataatat
     1201 gtgcatcgag tagttagaga aggagtaatt ttatgaaaat agcagttgct ggatcaggat
     1261 atgttggatt atcactagga gttcttttat cacttcaaaa cgaagtcact attgttgata
     1321 ttcttccctc taaagttgat aagattaata atggcttatc accaattcaa gatgaatata
     1381 ttgaatatta cttaaaaagt aagcaattat ctattaaagc aactttagat agcaaagcag
     1441 cttataaaga agcggaactg gtcattattg ccacacctac aaattacaac agtagaatta
     1501 attattttga tacacagcat gttgaaacag ttatcaaaga ggtactaagc gttaatagcc
     1561 atgcaactct tatcatcaaa tcaacaattc caataggttt cattactgaa atgagacaga
     1621 aattccaaac tgatcgtatt atcttcagcc ctgaattttt aagagaatct aaagctttat
     1681 atgacaactt atatccaagc cgaattattg tttcttgtga agaaaacgat tctccaaaag
     1741 taaaggcaga cgcagaaaaa tttgcacttt tattaaagtc tgcagctaaa aaaaataatg
     1801 taccagtact tattatggga gcttcagaag ctgaagcagt aaaactattt gccaatactt
     1861 atttagcgtt aagggtagct tattttaatg agttagacac ttacgcagaa tcgagaaaat
     1921 taaatagtca catgattatt caaggaattt cttatgatga tcgaatagga atgcattata
     1981 ataacccatc atttggttat ggaggttatt gtctacctaa agatacgaag caattattgg
     2041 caaattacaa taatattccc caaacgctaa ttgaagctat cgtttcatca aataatgtgc
     2101 gcaagtccta tattgctaag caaattatca acgtcttaga agagcgggag tccccagtaa
     2161 aagtagtcgg ggtttaccgt ttaattatga aaagtaactc agataatttt agagaaagtg
     2221 ctatcaaaga tgttattgac attcttaaaa gtaaagacat taagataatt atttatgagc
     2281 caatgttaaa caaacttgaa tctgaagatc aatctgtact tgtaaatgat ttagagaatt
     2341 tcaagaaaca agcaaatatt atcgtaacta atcgctatga taatgaatta caagatgtta
     2401 aaaataaagt ttacagtaga gatattttta atagagacta gccatgtctt catctataac
     2461 aataatattc atttttactt taaaagaact gcagttggtg gtatgattga gcactatgaa
     2521 atagtcgaaa aatcatatga aaacgtaaca tgatgtcaaa tgaattccgt tctgaaaacg
     2581 aatgtcacta agccatagat tataaaaagt gaggagttac tgatgaccaa agtcagaaaa
     2641 gccattattc ctgctgcagg tctaggaaca cgttttttac ctgctaccaa agctcttgcc
     2701 aaagagatgt tgcccatcgt tgataaacca accatccagt ttatcgtcga agaagcgcta
     2761 aaatctggca tcgaggaaat ccttgtggtg accggaaaag ctaaacgctc tatcgaggac
     2821 cattttgatt caaactttga attagaatac aacctccaag ctaaggggaa aaatgaactg
     2881 ttgaaattag tggatgaaac cactgccatt aaccttcatt ttatccgtca aagccaccca
     2941 agaggactgg gagatgctgt cttacaagcc aaagcctttg tgggcaatga accctttgtg
     3001 gtcatgcttg gagatgactt aatggacatt acaaatgcat ccgctaaacc tctcaccaaa
     3061 caactcatgg aggactatga caagacgcat gcatccacta tcgctgtgat gaaagttcct
     3121 catgaagatg tgtctagcta tggggttatc gctcctcaag gcaaggctgt caagggcctt
     3181 tacagtgtag acacctttgt tgaaaaacca caaccagaag atgcgcctag tgatttggct
     3241 attattggtc gttacctcct aacccctgaa atttttgata ttttggaaag acagacccct
     3301 ggagcaggta acgaagtgca actcacagat gctatcgata ccctcaataa aactcagcgt
     3361 gtctttgcac gagaatttaa aggcaatcgt tacgatgttg gggataaatt tggattcatg
     3421 aaaacatcta tcgactatgc cttagaacac ccagaggtca aagaggactt gaaaaattac
     3481 attatcaaac taggaaaagc tttggaaaaa agtaaagtac caacacattc aaagtaatgt
     3541 gttggtactt tacttttttc cttgtttata gcaacttaag tttatatctt gaaaattgtc
     3601 aacgttccaa aatataaaag ttttgtgtta tacaacttta ctagagggac atattaataa
     3661 taggatttat acgtagaaaa atgataaaca taagtacagc ttttgttaaa actaattaac
     3721 aagaacttca aaactaaata gttatttgga cgagtatgat actttataaa tagctcttat
     3781 tcagctatta ttatttattt ctgttttatg ctataatgac ttgaatgaca aaatggagat
     3841 gacaatgata tacaaattat ttacagaatt tatcacccta caagcccttc ttaaagaatt
     3901 aggaattatt caaagtggtg gcgctatcaa gggatttctc gctgaaacaa ccgttctatt
     3961 taatggtgaa gatgagaaac gtcgaggcaa aaaaatcaga gtaggggata agatttctct
     4021 acctgaccaa gacttaatta tcactattgt tgagcctagt caagaagaaa aagaacaatt
     4081 tgccgaagaa atggctgaaa agacacgtgt agcggctcta gtgaaacaaa tgaaccaagc
     4141 taacaaaaag acttcttcta aacataacaa tcgtcaatct actaccaaaa aatcactaag
     4201 agcaactaag aaaactaaag gtaaaccaac tgcacctgtc cgcttcccag gtatctagta
     4261 tgtggattaa agagttagag ttaaaacatt atcgcaatta tgaccacctg cttgcctcat
     4321 tttcgtcggg tttaaatgtc tttatcggta ataatgctca aggaaaaacc aattttctcg
     4381 aggcaatcta ttttctatca cttactagaa gtcatcgcac gagggctgat aaagaattga
     4441 ttcattttga tcactcaact gtttctctta ctggtaagat tcagcgtatt agtggtactg
     4501 ttgatttaga aatcaatcta tcagataaag gacgtgtgac aaagattaat gcgctaaagc
     4561 aagcaaaatt atctgattat attggaacga tgatggttgt gctttttgca ccagaagatt
     4621 tgcaactagt taagggagca cctagccttc gtcgcaaatt tatcgacatt gaccttggtc
     4681 aaattaagcc tgtttactta tctgagttat cccattataa ccacgtgctt aaacagcgta
     4741 atagctattt aaaaagtgcc caacaaattg atgccgcttt tctagctgtt ctagatgagc
     4801 aattagctgg ctatggagcc cgtgtcatgg aacatcgtat tgattttatc aatgcgttag
     4861 agaaagaagc aaatactcat caccaagcca tctcaaatgg tttagaaagt ctctctctct
     4921 cctatcagtc gtcagttgtc tttgacaaaa aaactaatat ttaccaacaa tttttacacc
     4981 aacttgaaaa aaatcatcag aaagatttct tccgtaaaaa cactagcgtt ggtccacatc
     5041 gcgatgactt agccttttac attaacggga tgaatgctaa ctttgctagt caaggtcagc
     5101 accgcagcct tattctttcc ttaaaaatag ctgaagttag tttaatgaag gccttgactg
     5161 gagataatcc cattctttta ctagacgatg tcatgagcga gctagacaat acacgacaaa
     5221 caaagttact tgaaacagta attaaagaaa atgtccaaac ctttatcaca acaacaagtt
     5281 tggatcacct gtcacagttg ccagaaggta tccgtatttt tcacgtgaca aaaggaaccg
     5341 ttcaaattga ttctgatatt cactaataac atcaaaaaag ggttcagtta aactgagcct
     5401 ttttttgata ttatgtggcg attaagattt gaccacacct aataacatag cacctacgat
     5461 aaaacaaata attcctgtga caacccaacg catttctttt ttggttttgg tttcgcctag
     5521 gaataaaatg cctccgacaa tcgaaatgat agcacctaat tgtgagaaac taaaggcaat
     5581 agcaagtcct gcttttgatg cagctaaaag cataaaaata ttcccaatgc cccaaagtaa
     5641 tccaacaacg ctatttttaa tcacatactg gtcaatggaa attttaaatg acatgaaagt
     5701 tatggctcct aaaaccatac ctactgccat gggtaaaatg actgacaaaa cttcaaattt
     5761 catgatgtta ttaaataata cagcatacat cacgtaacca attgttgaat aagtgagcgc
     5821 cctaaatcct tttgaaaaat tatgaaggtg attgacttgt gcattagcat catcttgttt
     5881 actagaaaag taaaaaccaa taatcagaag taatagtgct agacttccta ctacaaattg
     5941 cataggtctt gtccattcat gaaaaacgag cacaccaatc aaacttccca gaacaagttg
     6001 agagccactt gacaaaggat tggcaacgga gactcccgta tattgcatgg catgaaattg
     6061 accagtttga ccaattgacc agataaaacc gcctaaaatc ccaaaaatcc aaagttgcag
     6121 tgtcatctca ggtctaacaa ttaaccaaac agctaatgaa aataataaag ccccaaaagt
     6181 cattcctaga gtttgttgcg aaggttttcc tccaattttg ttactaacaa atccaatgct
     6241 tccccatgta aacatgggaa taagtgcata aaaaatacct tccaaaatgt tatctccttt
     6301 atagtaaatc tttaaagatt ataataattc tatcataaaa tggtttcatg taaagactaa
     6361 ttatagctta t
//
LOCUS       DATTYN010000050         6303 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.50, whole genome shotgun sequence.
ACCESSION   DATTYN010000050 DATTYN010000000
VERSION     DATTYN010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6303
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.50"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(244..552)
                     /locus_tag="VB649_001752"
     CDS             complement(244..552)
                     /locus_tag="VB649_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670679.1"
                     /translation="MTRLISQQILSEYVKSLEVEADKVVIPGQNTPVFSWDRDGNLSI
                     DTPLLKVRGESLATQADLTTISLTPGPKGELWQTSVERLDIKVDKHISLTFKNGVRID
                     "
     gene            complement(618..1070)
                     /locus_tag="VB649_001753"
     CDS             complement(618..1070)
                     /locus_tag="VB649_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEP1670680.1"
                     /translation="MGLLDLIERKRARDKPQNSYEGQDFSYLFGRTTSGENVDEFKAM
                     QTTAVYACVRILAEAVASLPIHIYERTENGKEKKLDHPLYFLLHDEPNPEMSSFIFRE
                     TIMSHLLIWGNAYVQIIRDKSGMVSLLLKQKASVLIRKLLLIIWQRMP"
     gene            complement(1175..1447)
                     /locus_tag="VB649_001754"
     CDS             complement(1175..1447)
                     /locus_tag="VB649_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670681.1"
                     /translation="MELVKTIQIGDDIYLPIPDPFGIQENQEFNLYKSTDGTLVLSPS
                     DSKLSADHQSISSDEQMTTAVEQARLDEIATSVLSRHLDAFKELTE"
     gene            complement(1466..1771)
                     /locus_tag="VB649_001755"
     CDS             complement(1466..1771)
                     /locus_tag="VB649_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP1670682.1"
                     /translation="MKEYQVTMSDDAKADLLSIYHYVRDELCAPQAADNLLERLSQAM
                     LSLSIFPERCAIIEDLIGKGYTFRQLIVKKYRIVYHVLEDEVIIVAVVYGSRHMNNW"
     gene            complement(1771..2073)
                     /locus_tag="VB649_001756"
     CDS             complement(1771..2073)
                     /locus_tag="VB649_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEP1670683.1"
                     /translation="MAKTGTLNLRVDDSVKSAADDILKRLGIPMSTAIDMFLNQIILT
                     GGIPFDVSLPEAPQRVNVDYMSQEKFYDKLITSFEDAKTGNRQDVREFLFQLKENA"
     gene            complement(2128..2304)
                     /locus_tag="VB649_001757"
     CDS             complement(2128..2304)
                     /locus_tag="VB649_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HEP1670684.1"
                     /translation="MGQNVVIRQAPAGNIKPDKEKSVEKIDGIVGLILVLDRCIRRQG
                     DEASVYDERGILSF"
     gene            2329..2970
                     /locus_tag="VB649_001758"
     CDS             2329..2970
                     /locus_tag="VB649_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670685.1"
                     /translation="MLDFPFHHEFIEFLGRWTHILITLPKRHHGQVDTAIPRYLLVTI
                     REKTGIVKLTTVQNTAFTTQSNQLKKQYGQFLLTESNNCCACPSCDRPLILTSGNLAA
                     ENYEVSAIEKDKDAEPLNLIALCPDCFLTYQADSRKKVVTTLKNVKKILVSAHNSQQA
                     ISDMKLDSGIVSVLTSLNKLKCDEYDISMATLQDIYFCQMIVSYFIQKCEVLE"
     gene            2970..3194
                     /locus_tag="VB649_001759"
     CDS             2970..3194
                     /locus_tag="VB649_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670686.1"
                     /translation="MQLPNKLYSYQKSTLAYLPRVLNEIKSGNSNVKDIFLAISEELD
                     DPTDFLSIMDCLYALNAIEMSNEGEVKLCL"
     gene            3185..4357
                     /locus_tag="VB649_001760"
                     /pseudo
     CDS             3185..4357
                     /locus_tag="VB649_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991604.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            4370..4843
                     /locus_tag="VB649_001761"
     CDS             4370..4843
                     /locus_tag="VB649_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2326 domain-containing protein"
                     /protein_id="HEP1670687.1"
                     /translation="MKRSTEDILLDLEVKINSKMREVNNILYPDIRKAPQINLNAHNS
                     YSFYTPDDDGTGTKFKGMIVFDLVMLYLTNLPALAHDSLLLSTVSYQTTEALLKLYDQ
                     SRSLNKQVFLAFDKASSYSPDANQLLSENTVLRLSSNGNELYGISWNKGENSDEI"
     gene            4833..5042
                     /locus_tag="VB649_001762"
     CDS             4833..5042
                     /locus_tag="VB649_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670688.1"
                     /translation="MRFSYNKLWKLLIDKGWTKTKLRQEAGISSSTIAKLGKGENITT
                     DILLKICIALDCKIEDIVEIVDNNI"
     gene            complement(5144..6283)
                     /locus_tag="VB649_001763"
     CDS             complement(5144..6283)
                     /locus_tag="VB649_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEP1670689.1"
                     /translation="MFDFANNTFLAGLNPASLSLVAVYQSLESVIGVLFNLFGGVIAD
                     SFKRKKIIITTNILCGTACLVLSFLTKEQWLVYAIVLTNVILAFMSAFSGPSYKAFTK
                     EIVKKDSISQLNSLLETTSTVIKVTVPMVAIFLYKLLGIHGVLLLDGLSFLIAALLIS
                     FILPVNDEVVIKEKVTIREIFNDLKIGFKYVYSHKSIFIITVLSALVNFFLAAYNLLL
                     PYSNQMFGEISTGLYGTFLTAEAIGGFIGAILSGFVNKELSSMRLILFLSLSGLMLML
                     APPFYIMFHNAIILALSPALFSLFLSIFNIQFFSLVQKDVDNDFLGRVFGIIFTITIL
                     FMPIGTGFFSVALNPNNSFNLFIIGSCITILSLVFRILFKKYNIR"
BASE COUNT         2121 a         1275 c         1040 g         1867 t
ORIGIN      
        1 tattaaaact cccactcaaa ctcctagtcc ctttgtttca agctatttag aacttttatt
       61 gtattatcca ctttattcct atttctgttg ctattagttt tatcatacaa tctaaccttt
      121 acccttttta gggagtgcaa aattcaaatg aatcgtgcat ctcaactccc aatataactt
      181 ctttcattat accacagata aactaaaaaa ggacgtgccg aattgatacg cccttgcctt
      241 ttatcaatca atccgtacgc catttttgaa ggttaggctg atgtgcttgt ctacttttat
      301 atccaacctt tcaacacttg tctgccagag ttctcccttt ggaccaggag ttaaagagat
      361 ggttgtaagg tcagcttgtg tcgctagact ttcccctctc acctttagga gcggtgtgtc
      421 aatggaaaga ttcccatccc tatcccaact aaagactgga gtattctgtc ctggaataac
      481 gaccttatca gcttcaactt ctaggctctt cacatactct gatagaatct gttgggagat
      541 aagccttgtc atccatgctg aactagagac ggtcaactca tcaatcttag ctttttgaag
      601 tgctgcaact cgtgcttcta aggcatccgt tgccagataa tcaagagcag ctttcttatc
      661 aaaacgctcg ccttctgctt tagcagtagc gataccatac cacttttatc tcgtataatc
      721 tgtacatagg catttcccca tatcaaaaga tggctcatga ttgtctctcg aaagataaag
      781 gaggacatct ctggattggg ttcatcatga agaagaaagt acagtgggtg gtccagcttt
      841 ttctccttcc cattttctgt ccgttcatag atgtgaatag gaagtgacgc caccgcttca
      901 gcaagaatac gcacacaggc atagactgcc gtcgtctgca tagccttaaa ctcatccaca
      961 ttctcgccac tagtcgtgcg accaaagagg taggaaaagt cctgaccttc ataactgttt
     1021 tggggcttat ctctagccct ttttctttca attaaatcaa gtagtcccat aagccctcct
     1081 tattttgggg tacaaaaaaa gcacctcctt tgaagtgctt tcggtatatt tctttcaaag
     1141 taatcaacag tctttcttac aaaacctagt attctcattc tgtcaattcc ttaaatgcgt
     1201 caagatgtcg tgataatact gaagtcgcaa tctcatctaa ccttgcttgt tcaacagctg
     1261 ttgtcatctg ctcatcactg cttatacttt ggtgatccgc tgatagtttg ctatcagatg
     1321 gacttaacac caaagttcca tcagttgatt tataaaggtt aaactcctga ttctcttgaa
     1381 tgccaaatgg gtcaggtatc ggaagataga tgtcatcacc aatttgtatc gtctttacga
     1441 gttccataca tcactctccc ttactttacc aattattcat atgacgtgat ccatagacga
     1501 ccgcaacaat tataacttca tcttccagaa catgatatac aatgcgatat tttttgacaa
     1561 tcagttgtct gaaagtatag ccttttccaa tcagatcctc aatgatggca caacgttcag
     1621 gaaaaatgga tagtgataac attgcttggg ataacctctc aagaagatta tccgctgcct
     1681 gtggtgcaca gagttcatca cgaacatagt gatagatgct cagcaaatct gctttagcat
     1741 catccgacat ggtgacctga tactctttca ttaagcattt tccttcaatt gaaatagaaa
     1801 ttctctgaca tcctgacggt tgccagtttt cgcatcttca aagctggtga taagcttatc
     1861 ataaaacttc tcctgactca tgtaatcaac attaactcgt tgaggcgctt caggtagaga
     1921 aacatcaaat gggatacccc cagtcaaaat aatctgattc aaaaacatat caatcgcagt
     1981 tgacatagga atacctaagc gtttcaaaat atcatctgcc gcacttttta ctgaatcatc
     2041 aactcgtaaa ttcaaagttc ccgttttagc catggttatc ctcctttttt gtaacgacat
     2101 tgtatcacat tttgggagtt gactcaacta aaaactcaat atccctcgct catcatagac
     2161 gctagcttca tcaccttggc ggcgaatgca acggtcaaga accaggataa gacctacaat
     2221 accgtcaatc ttctcaacag atttttcctt atctggcttg atgttgcctg caggggcttg
     2281 tcgtatcacc acgttttgtc ccatccattt aagaactggg tgaccaccat gttagatttt
     2341 cccttccatc atgagtttat agagttcctt ggacggtgga ctcatatcct tataaccctg
     2401 cccaaaaggc accatggtca agtcgacacc gcaattccaa ggtatcttct agtaaccatc
     2461 agagagaaga cagggattgt aaaattaacc actgtgcaaa atacagcgtt cactacccag
     2521 tcgaatcaac tcaaaaaaca atacgggcag ttcttgttaa cagaatctaa taactgttgt
     2581 gcatgcccaa gctgtgatag accactcatt ctaaccagtg gcaacttagc agcagaaaat
     2641 tacgaggttt cagccattga aaaagataag gacgctgaac cactgaatct gatagccctc
     2701 tgcccagatt gttttttaac ctatcaagca gatagtcgca aaaaagttgt aacaactcta
     2761 aaaaatgtta aaaagattct agtctctgca cataacagcc aacaagcgat ttctgatatg
     2821 aagttagaca gtggaattgt ttcagttttg actagtctca ataaactaaa atgtgatgaa
     2881 tatgatatct ccatggctac actacaggac atctacttct gccagatgat tgtctcttac
     2941 tttatccaaa aatgcgaggt acttgaataa tgcaattacc aaataaactt tactcctatc
     3001 aaaaaagcac tctggcctat ttacctagag tgctaaatga aatcaaaagt ggaaactcaa
     3061 acgtcaaaga tatctttctc gctatctcag aagagttgga tgatcctaca gattttctat
     3121 ccataatgga ttgcttgtat gcattgaacg ctattgaaat gtctaatgaa ggagaagtaa
     3181 aattatgctt atagaaatgt ggtctccagt atttaagaaa cacggagaaa ttcgggaacc
     3241 aatctgcttc caccatgggt taaacgtgat tatggggatg gatttagctg ataactctat
     3301 cggcaaatcc tcctcactat tagtcattga tttcatcttt ggaggtaata gctatctaaa
     3361 atcaattgcg gttaaaaaat taggtgatca tcctatctac ttctgctttc aatttgagaa
     3421 aaagttttat ttttcaagag atacggccaa cccagatatc attctagtgt gtgacaagag
     3481 ctactctcca accggtgaaa caatggacct aggaattttt cttaacaaac ttaagaaacg
     3541 atatcattta gattctccag agctatcatt ccgattagct atgagtggct tctttaggat
     3601 tgcaggaaaa agtaatcaaa ataccgattt ccccttacaa gtttattcga gccaaaaatc
     3661 ttctgaatct attactactc tcatccaact gtttaatttg tatgataaca ttgcacgata
     3721 caaagaacgt ctgaaagata agagcgacca gttaacaact tttcgtaatg ctcgaaagta
     3781 taccttcatc tccaacctgg ttggcggtaa aaagcaattt gaagcaaatg tctcagaaat
     3841 aaaaagattg gaatatgatt tagcacatct ccaagatact cagcaagata aaattgactc
     3901 tgatgatatt taaaaaaatc aacaaaaact ccaacttaga aatactaagc tggagttaga
     3961 aagcagtctt cgggacaagc aaagacgtct taagctattg gacatcagta tcgaatttgg
     4021 cttatatcct actgaatctg acttaacaga gcttcaacaa tacttcccag atactaatct
     4081 caaaaaatta tatgaagttg aagcttacca caaaaaattg gaaactattt tagattccga
     4141 attctcaact gaacgtgaat ccctaatagc tgagatcgac gaattagaga gtcaattaac
     4201 aactctaaac caagaacttc aagaactagg aaacatccca aatctttcaa gtgagtactt
     4261 agaaaactac tctaaactaa cagctacaat caatgcacta aaagaacaaa acgaggccta
     4321 cttaaaggag tctggtctat ccaaagaaaa atcataagcg gacactgact tgaaacgcag
     4381 tacagaagat atccttctag atctagaagt aaaaatcaac agtaagatgc gtgaagtcaa
     4441 taacattcta tatccagata ttcgcaaagc tcctcaaatt aacctaaatg ctcacaatag
     4501 ctactccttc tatacaccag atgatgatgg tacaggaact aagtttaaag ggatgattgt
     4561 attcgactta gtaatgctct accttactaa tctgccagca ctcgcacacg attcattact
     4621 cttgagtact gttagctacc aaacgactga agcacttttg aagctgtatg accagtcaag
     4681 gtcattgaac aaacaagtct ttttagcctt cgataaagcc agctcttatt ctccagatgc
     4741 taatcaactc ttgtcagaaa atacggtatt gagactctct agtaacggaa atgaactcta
     4801 cggtatttca tggaacaaag gagaaaactc agatgagatt tagttacaat aaattatgga
     4861 aacttcttat tgataaaggt tggaccaaaa caaagctcag gcaagaagct gggattagtt
     4921 cttccacgat cgcaaaattg ggaaaagggg aaaatatcac tactgatatt ttattgaaaa
     4981 tttgtattgc acttgattgt aagattgaag atatagtaga aattgtagat aataatatct
     5041 agaaataaaa aaagcactga gttgataaga tgtgtaagtc agatcaactt agtgccttta
     5101 ctttgaaaaa aataattttc tcaataatac ttagtactaa ctgttaacga atattatact
     5161 ttttaaataa tattctaaat actaatgaca atatagtaat gcacgaacca ataataaaaa
     5221 gattaaagct attgttagga tttaatgcca ccgagaaaaa gccagtccca ataggcataa
     5281 aaagaatagt tattgtaaag ataataccaa acactctccc taaaaaatcg ttatcaacat
     5341 ctttctggac aagagaaaaa aattgaatat taaagatgga aagaaataaa ctgaataaag
     5401 ctggtgacaa agctaaaata attgcattat gaaacataat ataaaatggg ggagctaaca
     5461 ttaacatcag tcctgataaa gatagaaaca atatcaatct catacttgat aattctttat
     5521 tcacaaaacc acttaatatt gccccaataa atccaccaat tgcttctgct gttaaaaaag
     5581 tgccataaag tccagttgaa atttctccaa acatttgatt actatagggc aacaataaat
     5641 tataagcggc tagaaaaaaa ttaacaagtg cagaaagaac ggtaataata aagatggact
     5701 tatggctgta aacatattta aatcctattt ttaaatcgtt aaatatttct ctgattgtca
     5761 ccttctcctt tatcaccact tcgtcattaa caggtaaaat aaaggaaatt agtaaagcag
     5821 ctattagaaa tgatagtcca tccaatagta atacaccgtg tataccaagt agcttatata
     5881 agaaaattgc taccatagga actgttactt tgattacagt acttgttgtc tctagcaatg
     5941 aattaagttg tgatatacta tcttttttaa caatttcttt tgtaaatgct ttataggatg
     6001 gaccagaaaa agcactcata aatgccaaga taacattagt tagtacaatg gcataaacca
     6061 accattgctc ttttgttagg aacgagagta ctaagcaagc tgtgccacat aagatatttg
     6121 tagtaataat aatttttttc cgcttgaaac tgtctgcaat gactccacca aataaattaa
     6181 atagaacacc tatgacactt tctagagact gatatactgc aactaatgat agagacgctg
     6241 gattaagccc agcaagaaaa gtattgttag caaaatcaaa cataacatcg ccaattcgat
     6301 ata
//
LOCUS       DATTYN010000051         6239 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.51, whole genome shotgun sequence.
ACCESSION   DATTYN010000051 DATTYN010000000
VERSION     DATTYN010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6239
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.51"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            185..349
                     /locus_tag="VB649_001764"
     CDS             185..349
                     /locus_tag="VB649_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670690.1"
                     /translation="MGIGSMTVTVKVTNIDKFVELSKEFNKKARELEELAHELQTFHF
                     EGDVASVDSN"
     gene            391..594
                     /locus_tag="VB649_001765"
     CDS             391..594
                     /locus_tag="VB649_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEP1670691.1"
                     /translation="MSKELKAIKAQVKVRLIELDMTQTQLANSVNVTKSVISDLLTYG
                     KGSSNVKANVAAVLGINNPWEGM"
     gene            727..1095
                     /locus_tag="VB649_001766"
     CDS             727..1095
                     /locus_tag="VB649_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670692.1"
                     /translation="MNNIRDMTIMEINVLNAIRNSASYDLPIQASELRTHFGLSKRTL
                     EEIIENLRVTYRHPIVAKKKRPSGYYLPRTEEERNDGLAPYRRQILTEQKNLSAVMSV
                     NLDDYWKEAKKPDGNQAQNK"
     gene            1135..1398
                     /locus_tag="VB649_001767"
     CDS             1135..1398
                     /locus_tag="VB649_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670693.1"
                     /translation="MEAMEVIRIRDVIIEKISACDEELAHIFGYSKRQATERRREMQK
                     LPSQQEHLRDGGQLVTIKGFDAYLKYRGTQAWKKEMEKIKKSK"
     gene            1413..1601
                     /locus_tag="VB649_001768"
     CDS             1413..1601
                     /locus_tag="VB649_001768"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670694.1"
                     /translation="MTENPLSAVIFLVILFLIAFLCRDDSEEQPKSVTKSRDDIVAER
                     YGRVMQIEHHEGSHYGRF"
     gene            1588..2928
                     /gene="dnaB"
                     /locus_tag="VB649_001769"
     CDS             1588..2928
                     /gene="dnaB"
                     /locus_tag="VB649_001769"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEP1670695.1"
                     /translation="MEDFKILPHDIQTEQAVLGSIFINPEKIIEVAEYLKPDDFYKPA
                     HRILFKAMLSISSNAEPIDVVTVKSVLESQDNLATIGGITYLLDVVNAVPTSSHAEHY
                     AKIVAKKAQLRSIIDNLSDSIGNAYDENMDIDEIIAKTERSLIEVSQSSNKSSFRPIH
                     DVLAENYQKIEERSNNNTQITGIATGFYDFDKLTTGLHADQLIILAARPAMGKTAFAL
                     NIAQNVATKSNKAVAVFSLEMGAESLVERMLASEGTIESHHIRTGQLTVEEWQRLIYV
                     QGELAEAPIFIDDTAGVKITDIRARARRLSQENDGLGLIVIDYLQLIQGSRSDNRQQE
                     VSEISRQLKIIAKELKVPVIALSQLSRSVEQRQDKRPIMSDLRESGSIEQDADIVAFL
                     YRDDYYTDKSDDQPESNLTELIIKKNRHGSLGTVNLYFHKEYTKFSSVREEKHD"
     gene            2921..3730
                     /locus_tag="VB649_001770"
     CDS             2921..3730
                     /locus_tag="VB649_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HEP1670696.1"
                     /translation="MIKKSEVTGFLAFFKFPKPFIYDEKYKVLSNNAKMLYMLLFDRL
                     ELSLKNGWHDKEGNVFQYYTNDQLMIDLNCNSNKTIIKIKKELKNAGLMTEVRQGMNL
                     PNRIYLEALNGSVENTFQEVQKVHLGSVENTFQEVQKVHLGSVENTLSEVQKVHTIKT
                     ENTKTENNNNKLLICKEVISYLNLKAKKNFKVDTASHHRFIKARLKEGYTLEDFKKVV
                     DVMSARWIGTEYEQYLQPQTLFGNKMDNYLNTTMPRRPELLASAVDERLGF"
     gene            3730..4542
                     /locus_tag="VB649_001771"
     CDS             3730..4542
                     /locus_tag="VB649_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEP1670697.1"
                     /translation="MKFQTKEVLDDLCEVHGCQLWMTLVPIKGKLEQLKQCPECTKAA
                     IGIFEKKLNAESEVNSKLADTYAVFNRDSLISDKLRAKSLDNYEIKSEIDQKAINFVK
                     RMEQFYRQDKTGNAIVTGPSGVGKSHLTYGFAKWLNEQFKAYDNPKSVLFVSVVSLFN
                     KIEESFTVDNGFSKAKMVDLLTRVDYLFLDDLGKESRKDGNKAKNEWRHQVLYEILDN
                     RGNTIINTNLTSKDIKQLYADDFGNGALSSRILEGVTGNSFVYPQETEDRRY"
     gene            4542..4769
                     /locus_tag="VB649_001772"
     CDS             4542..4769
                     /locus_tag="VB649_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670698.1"
                     /translation="MFKLQHIVNGFYPVNLGNFDNVQDAVDAIKAHVRANSAIINPRY
                     VKSMSGETIRIDYGAKDCYYLLTLINEANGC"
     gene            4783..4989
                     /locus_tag="VB649_001773"
     CDS             4783..4989
                     /locus_tag="VB649_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670699.1"
                     /translation="MTVKELIAKLQEFPDFMNVKISLIDVDLLEVLEFEEFPTKAKII
                     TEDINSIDVERTDISEITISAIGC"
     gene            5006..5440
                     /locus_tag="VB649_001774"
     CDS             5006..5440
                     /locus_tag="VB649_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670700.1"
                     /translation="MIPKYRAFNKKTKKMYGVDGFRAFERKIYRCSLADDEFRHGHME
                     IIHFVEDSLDDYILMQSTDLEDKNGIEIFEDDVVKLKYTIASDLEFFRVTRFRGGSWR
                     IDNRRRGSELWLRNKDCEVCGNVYQNPDLMDIIQETLESVKE"
     gene            5437..5721
                     /locus_tag="VB649_001775"
     CDS             5437..5721
                     /locus_tag="VB649_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670701.1"
                     /translation="MTTDELLQNLRDDLNKIINVLKNDWKALLFLAIAIFGIMVTVSY
                     FSYRDAQQYYEPQITGLRTQLSRTQKQLKRASEQNQRQTKRIAELTGNGG"
     gene            5724..6206
                     /locus_tag="VB649_001776"
     CDS             5724..6206
                     /locus_tag="VB649_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP1670702.1"
                     /translation="MSDIRILDACCGSRMFWFQKDEPHTTYIDRREEQFEIYRKHINV
                     RPDIVADFRDMPFDDETFNLVVFDPPHLLWAGQNSIMRAQYGQLDKENWKEDISKGFE
                     ECMRVLKVGGTLVFKWSDCQINVKEVLSAIPFKPLFGQQRGTTHWMTFVKFELTGNGG
                     "
BASE COUNT         2174 a         1008 c         1390 g         1667 t
ORIGIN      
        1 tagttagcga acaagacaac taaaaaaata aaacatagaa aactgattgg cgtccgtttt
       61 tctaagggaa taacttacat tttagtaggt cttttctcta tggtttgatt ttaataaatt
      121 tatttataaa tgtcaataag ttcgctaact ttttagttaa ttttttaaaa aggaggaaag
      181 acaaatggga attggctcaa tgactgtaac tgtaaaagtt actaatatag acaaatttgt
      241 tgaacttagt aaagaattta acaaaaaagc tcgtgagcta gaagaacttg ctcacgaact
      301 tcaaacattc cattttgaag gtgatgttgc atcagttgat agcaactaac tcaaaatcat
      361 catcttcttt aaaaacatag aaaggcaatt atgagtaaag agttaaaagc aattaaagct
      421 caagttaaag tacgtttaat tgagctagat atgacacaga cacagctagc aaacagcgta
      481 aatgtgacta agtctgttat atctgactta ctgacatacg gtaaaggcag tagtaatgta
      541 aaggcaaatg tcgctgccgt attaggtatt aataatcctt gggaggggat gtgaaatgac
      601 agctaaaatt atttcaaatt ggcaaaagaa aaatcaccag cttagtcaac tgatgataga
      661 tagtcttgaa ggactagata tttgggagac tgtcctagct ttgggaagat taaggaagaa
      721 acaagtatga ataatatccg agacatgacc atcatggaaa tcaacgtgct caatgctatc
      781 agaaatagtg ctagctatga ccttcctatc caggcaagtg agctgagaac tcattttgga
      841 ctgagtaagc gaacacttga agaaatcatt gaaaatctaa gggtgactta tcggcatccc
      901 attgtggcca agaaaaaacg gccaagcggt tattatctgc cacggacaga ggaggagcga
      961 aacgacgggc ttgcaccgta tcgcagacaa atcctaaccg agcagaaaaa tctatctgcg
     1021 gtgatgtcgg tcaacttaga cgattactgg aaagaagcaa aaaagcctga cggcaatcag
     1081 gctcaaaata aataatattt acttgaatta tagcatgaaa cggaggtttt ggctatggaa
     1141 gcaatggaag ttattcgtat tcgtgatgtg attattgaaa aaatttcagc ttgtgatgaa
     1201 gagttagctc atatatttgg atatagcaag agacaggcta cagaacgtcg tcgtgagatg
     1261 caaaaattac cgagccaaca ggaacatctg agagatggtg ggcagttagt aactatcaag
     1321 ggctttgatg cctatttaaa atatagagga actcaagcct ggaaaaagga aatggaaaaa
     1381 ataaaaaaat ctaagtagag tagaggaaaa acatgacaga aaatccacta agcgcagtta
     1441 tctttttagt catcctattt ttaatagcat ttctatgtag agatgacagc gaagaacaac
     1501 cgaagtcagt aacaaaatcc agagatgata ttgtagctga gcgatacgga agagtaatgc
     1561 agattgagca tcacgaagga agccactatg gaagatttta aaatattgcc ccatgatatt
     1621 cagacagagc aggcagttct tgggtctatc tttatcaatc ctgaaaaaat cattgaggtg
     1681 gctgagtatc ttaagccaga tgatttctat aaaccagcac acagaatatt attcaaggcc
     1741 atgctaagta tttctagcaa tgctgagcct attgatgtcg tcacagttaa atcagtgcta
     1801 gaaagtcaag acaatcttgc tactattggc ggaataacct atctgctaga tgtagtcaat
     1861 gcagtaccaa caagctcaca cgctgaacat tatgcaaaga ttgtggctaa aaaagcacaa
     1921 cttagatcta tcattgacaa tctttctgat tctattggca atgcctatga cgagaacatg
     1981 gacattgacg agattatagc aaaaactgag cggtcgttga ttgaggttag tcaatctagt
     2041 aataagagta gttttagacc tatccatgac gtgctagcag aaaactatca aaaaattgaa
     2101 gagcgatcaa acaataatac tcagattaca ggtattgcta caggcttcta tgactttgac
     2161 aagttaacaa cgggattaca tgcagaccaa ttaattatct tagcagctag acctgccatg
     2221 ggtaagacgg catttgctct taatatcgct cagaatgtgg caactaagtc taataaggct
     2281 gtggccgtct tctcgcttga aatgggtgcc gaaagtctag ttgagcgtat gcttgctagc
     2341 gagggaacta ttgagagtca ccacatcagg actggtcaat taactgttga ggagtggcaa
     2401 cggcttatct atgtgcaagg agagcttgct gaagcaccta ttttcataga tgacacggct
     2461 ggcgtcaaaa ttactgacat tagagcaaga gccagaagac tatcgcaaga aaatgatggt
     2521 ttagggctca ttgtcattga ctatcttcag ttaatacaag ggtcacgttc agacaatagg
     2581 caacaagaag tctctgagat ttctagacag ttaaagataa ttgctaagga attaaaagtg
     2641 cctgtcattg ctcttagcca actatcacgc agcgttgagc aaaggcagga caagagacct
     2701 atcatgtcag acttaaggga gtcaggaagc attgagcaag atgctgatat tgtcgccttt
     2761 ttatatcgtg atgattacta tactgacaaa tctgacgatc agccagaaag taatctgact
     2821 gagttgatta tcaagaaaaa taggcatggc agtcttggca ctgttaacct atattttcat
     2881 aaagagtaca ctaaattttc tagtgtaagg gaggaaaaac atgattaaaa agagtgaagt
     2941 cacaggattt ctagccttct ttaaatttcc gaagccattc atctatgatg aaaaatataa
     3001 agtattgagc aataacgcta aaatgctcta tatgcttctg tttgatagac tagaactatc
     3061 tttaaaaaat ggctggcatg ataaagaagg caatgtcttt cagtattaca caaatgacca
     3121 gctgatgatt gacttgaatt gcaacagtaa caaaacaatt atcaaaatca aaaaggaatt
     3181 aaaaaatgct ggtctaatga cagaagtcag acaaggaatg aacttgccaa accgtattta
     3241 tcttgaggct cttaatggaa gtgtagaaaa tacatttcag gaagtgcaaa aagtacacct
     3301 tggaagtgta gaaaatacat ttcaggaagt gcaaaaagta catcttggaa gtgtagaaaa
     3361 tacactttcg gaagtgcaaa aagtacacac aatcaagact gagaatacta agactgagaa
     3421 taacaataat aaattgttga tttgtaagga agttatctca tatctgaact tgaaagctaa
     3481 gaagaatttc aaggttgata ctgctagcca ccatagattc attaaggcac gtctcaaaga
     3541 aggctacacg ttggaagatt tcaagaaggt ggtggatgtc atgtctgcta gatggattgg
     3601 gacagagtat gagcaatatc tacagcctca gacccttttc ggaaacaaga tggacaacta
     3661 tcttaataca acaatgccaa gacggccaga gttgttagct agtgcagtag atgaaaggtt
     3721 gggattctga tgaaatttca aacaaaggaa gtgttggatg atctttgtga agtgcatggc
     3781 tgtcagctat ggatgacact ggtacccatc aaaggtaaac tggaacagct caagcagtgt
     3841 ccagagtgta ccaaggcagc gattggtatt tttgagaaaa agctcaatgc tgagtctgag
     3901 gtcaatagca agctggctga tacttatgcg gtctttaatc gtgatagctt gatcagcgat
     3961 aagctgaggg ctaagagtct ggataactat gagattaagt ctgagattga tcaaaaggcc
     4021 attaactttg tcaagcggat ggagcaattt tacagacagg ataaaactgg caatgccatt
     4081 gtgactggtc catctggtgt cggtaagagc catctgacct atggttttgc caaatggctg
     4141 aatgagcaat tcaaagccta cgataatcca aagagcgttc tttttgtgtc ggtggtgagc
     4201 cttttcaaca aaatcgaaga gagcttcacg gtggacaacg gcttttcaaa ggctaagatg
     4261 gtggacttgc tgacgagggt ggattatctt tttctggacg atcttggcaa ggagagtaga
     4321 aaagacggca ataaagctaa gaacgaatgg cggcatcaag tactgtacga aatcttggac
     4381 aatcggggca acaccatcat caacacaaat ctgacaagca aggacatcaa acaactctat
     4441 gcggatgact ttggcaacgg tgctctgtct agtcgtattc ttgagggtgt gactgggaat
     4501 agctttgtct atccgcaaga gacggaggat aggagatatt gatgtttaaa ctacaacata
     4561 ttgttaatgg gttttatcca gttaaccttg gcaactttga caatgttcaa gacgcagttg
     4621 atgccatcaa ggcgcatgtt agagctaact ccgcaatcat aaatccacga tatgtaaaga
     4681 gtatgagtgg cgaaactatc agaattgatt atggtgctaa ggattgctat tacttgttaa
     4741 ccttgataaa cgaggctaat ggatgctaga acaggtggaa acatgacagt aaaagaactg
     4801 attgctaaat tacaagaatt tcctgatttc atgaatgtca aaatttctct aattgatgtt
     4861 gatttgttgg aggttctaga gtttgaggaa tttccgacaa aagcaaaaat aatcacagaa
     4921 gatatcaatt ctattgatgt tgaacgtaca gacataagcg aaataacaat atcagctatt
     4981 ggatgttaga aagcgtggaa gtggaatgat accaaagtat agagcattta ataaaaagac
     5041 caaaaaaatg tatggcgttg atggatttcg agcatttgag cgcaaaatat acagatgcag
     5101 cttagcagat gatgagtttc gccacggaca tatggagata atccattttg tagaagatag
     5161 ccttgacgat tatatcctca tgcaatcaac agacctcgag gataaaaatg gcattgagat
     5221 ttttgaggat gacgtcgtta aattaaaata tacaattgct agcgatttgg aattttttag
     5281 agtaacccga tttagaggtg gatcttggcg gattgataat agacgacgag ggtcggagtt
     5341 gtggctgaga aacaaggatt gcgaagtttg cggtaacgtg tatcaaaacc cagacctaat
     5401 ggatattata caagaaactc tagaaagcgt gaaagaatga caacagatga attattacaa
     5461 aatttacgtg atgatttgaa taaaataatt aatgtcctaa aaaacgactg gaaagcacta
     5521 ttgtttcttg caatcgcaat atttggaatc atggtaactg tgtcgtattt tagctaccgc
     5581 gacgcacaac aatattacga accgcaaatc acaggactac gtacacagct aagcagaaca
     5641 caaaagcagc ttaaacgtgc gagtgagcaa aatcagagac agacaaagcg gattgcggaa
     5701 ttgacaggaa atggggggta aggatgtcgg atataaggat attagatgca tgttgcggga
     5761 gcaggatgtt ttggtttcaa aaagatgagc cgcacacaac atatatcgac cggcgtgaag
     5821 aacagtttga aatctacagg aaacatatta atgttaggcc agatatagta gcagatttta
     5881 gagatatgcc atttgatgac gaaacattta acctggttgt cttcgaccca ccacatttat
     5941 tatgggctgg acaaaactca attatgaggg ctcagtatgg ccaacttgat aaagaaaact
     6001 ggaaagaaga tatttcaaaa ggtttcgaag aatgtatgcg agttttaaaa gtcggtggca
     6061 ctttagtttt taaatggtct gattgtcaga taaatgtaaa ggaagtttta tcagcaatac
     6121 catttaagcc actatttggc cagcaaagag gtactacaca ttggatgaca tttgttaaat
     6181 ttgagcttac tggaaatggg ggatagtgat gtgaaatgcg aattgtataa tgatcattt
//
LOCUS       DATTYN010000052         5637 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.52, whole genome shotgun sequence.
ACCESSION   DATTYN010000052 DATTYN010000000
VERSION     DATTYN010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5637
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.52"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            16..303
                     /locus_tag="VB649_001777"
     CDS             16..303
                     /locus_tag="VB649_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-damage-inducible protein J"
                     /protein_id="HEP1670703.1"
                     /translation="MTTVKKNRAVTFQANKELVSEAMTVLNKKNLTLSSALRLFLQNV
                     VVTNEVDLLTEEELEKEKLFKQFQAEINKNIEDVRQGKFYTSEEVRAELGL"
     gene            293..628
                     /locus_tag="VB649_001778"
     CDS             293..628
                     /locus_tag="VB649_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEP1670704.1"
                     /translation="MDYKKYQIIYAPDVLEKLKEIRDYISQNYSSTSGERKMEQIISD
                     IEKLEVFPEVGFDADEKYGSKISHYHSTKGYTLSKDYIVLYHIEGEENRVVIDYLLPT
                     QSDYIKLFK"
     gene            780..1229
                     /locus_tag="VB649_001779"
                     /pseudo
     CDS             780..1229
                     /locus_tag="VB649_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            1265..1765
                     /locus_tag="VB649_001780"
     CDS             1265..1765
                     /locus_tag="VB649_001780"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEP1670705.1"
                     /translation="MDFQSETLSVNKSLGRLDGKTIEKSTKNDFSVRKIKLDSETISI
                     LQEWKAVSQKEKTQLAVAPLSIKSDFIFTYCTREGSIEPLHADYINNILSKVIKQHSL
                     KKISPHGFRHTHATLMIEIGVDPVNTAKRLGHANSQITLDTYSHATAVGEDKSIKQFA
                     NYLKNN"
     gene            complement(2063..2392)
                     /locus_tag="VB649_001781"
                     /pseudo
     CDS             complement(2063..2392)
                     /locus_tag="VB649_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366816.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            2767..>5637
                     /locus_tag="VB649_001782"
     CDS             2767..>5637
                     /locus_tag="VB649_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEP1670706.1"
                     /translation="MTIPSILNYQGNKSSLIPFLKQNIEKYLEPGEIFFDIFSGSGSV
                     GASFQQENIIFSNDAELYSTIISSSLLNTPEETLLQEIADQFQTQLKKNINKNSIEYI
                     DYIKQEREFLLSQDNDKLINLYKNFPTIWNKLRGVTVNKLSKQRKYNLFTHYYSGTYF
                     GIEQSIIIDSVIETIHSFQNESVTDTLYSCLFFAMKEIVFAKDGHMAQPLNPSKNITR
                     HFKQRSKNLIDLLNKKLEEFILYSSKKVSNKQFQHQIYNLDIREITNNNLLANSNIKM
                     IYADPPYTDMQYSRYYHLLNVAARYDFPEPTINHGKYTSGLYTEGRNQSDLSKKSTAK
                     NRIEDLCLYCKENNIILTLSYAYPEDQINQKIDRYTVSIEDLIDLTKKIFGSSNVTIA
                     EENYKHANHRNSSTKKVIEYLIICGPPSTENDHPNSLLNLKYDIKTTIPTSKNPIYNT
                     HLYWSQKSFNIIDKLIQHLSKEGDTIFDPFMGSGVTILETIKNSLNRKAIGCDVNEMP
                     RFIVTNIINNFQKKELVEVFNKLEKKLDELTSYYTTTCTSCNSEKAIISKIVFDKPSR
                     TINDYNIKAVNYTCPNCGKNTKQADINDENKMLSLVCSDHIFDEQLLKNSKIAVGDND
                     HLSDLFTPRNFSLLNEIVGYISSSGDPDILNYLLMSCIHLCKITDLHSNSQWPLWIPK
                     KNCVEKNIIDLLKKRIKNIIKATNFVEKNYLNSHIVSDYTKLTTNSALVLTKGSQYIT
                     EYEVPDNSIDLIITDPPYKDQVLYSEYMQLYKPIIGLDFNLEDEIVVSPSPIRKRAES
                     EYFNLLNQVFELCSKKLKQGSFMCLFFHDSNLSVWAELITILEHNGFKYISQEHIKKS
                     KTVKNIISPKKSLSGDAILFFENTKHEIKSYDTNISADEIAHYIYLESKKLLESKGEL
                     STPELYDFGLMEILINNGWLEILSSKYKTLVDIFEEKFIWNSV"
BASE COUNT         2126 a          984 c          868 g         1659 t
ORIGIN      
        1 aaggggttac ataaaatgac tacagtaaaa aaaaacagag cggttacctt tcaagctaat
       61 aaagaattgg taagcgaagc aatgacagta ttaaacaaaa aaaatttaac cttatcatct
      121 gctttaagat tattcctaca aaatgtcgtt gtcacaaacg aggttgactt attgacggaa
      181 gaggagttag agaaagaaaa acttttcaag caatttcaag ctgaaatcaa caaaaatatt
      241 gaggatgttc gtcaagggaa gttttatacc tctgaagaag tgagggctga acttggacta
      301 taagaaatat cagattatct atgctcctga tgttttagag aagctaaaag aaattcgtga
      361 ttatatttct caaaactact cctcaacatc aggtgagcgt aaaatggagc aaatcattag
      421 cgacatagaa aaactcgagg ttttcccaga agttggtttt gatgccgatg aaaaatatgg
      481 ttcaaaaatc agtcattatc acagcactaa aggttatacc ttaagtaaag attatattgt
      541 cctataccat atcgaggggg aagaaaatag ggtcgttatt gattacttgc ttcctactca
      601 aagcgactat ataaagttat tcaaataaca cgttaaaagc cttagcagtc ttgctagggc
      661 ttttttggta gattaccaat taactaggag caaaatgagt tcgggctgtt tagtagatat
      721 tccacaaaga agccaaagac tacgaagcta ggctaatcta ccttaaggct tcaggaaact
      781 tggaggagtt caccaagcca actcataaaa cttatagcga gatattcgag aaatggtatc
      841 aagcttatca agatatggta gagccaacca cggcttctcg tactcttgat ctgtttcgac
      901 ttcacatttt gccagtcatg ggagaattgc ccattaacaa aacctcccct ttagactgct
      961 agaacttcat caccgataaa gcaaagacct ttaagaatat caagcaaatc aagtcctaca
     1021 ctgaaaaggt ctttgatttt gccatcaaga tgaaactgct caagcataac cctatggctg
     1081 aaatcattat gccaaagcgg aaaaaaatac ggatagaaaa ctattggacg gttcaagaac
     1141 ttcaggagtt tttagccata gtacttcaga aagagcctta caagcactac gcactatttc
     1201 ggctactagc ttatagcggc cggccttaag gaaaggcgag ctatgcgctc ttaaatgggt
     1261 tgatatagac tttcagagtg agacactaag cgtcaataag agcctaggac gattagacgg
     1321 aaagacaatc gaaaaaagca ctaaaaatga tttctcagta agaaagatta agctagacag
     1381 cgaaactatt tctattctgc aagaatggaa agccgtcagc caaaaagaaa agacacaact
     1441 agcagttgca cctctttcaa ttaagtctga ctttatattt acatactgta ctagagaagg
     1501 gagtattgaa ccacttcatg cagactatat taacaatatc ttatcaaagg tcattaagca
     1561 acatagtctt aaaaaaataa gtcctcacgg cttcaggcat acccatgcaa ccctgatgat
     1621 tgagattgga gttgacccag taaatacagc caaaaggtta ggacatgcta atagtcaaat
     1681 aactcttgat acatacagtc atgctactgc agtcggagaa gacaaatcaa tcaaacaatt
     1741 tgctaactat ctcaaaaata actaaataaa cgtattaaac caagtcaaaa gttttccgaa
     1801 acggtatcaa aaaaaggtat caaaagcaaa aaacgacaaa aaagcacctt gcaagagact
     1861 tgcaaaatgc ttgtaatcgt tgatgtaaag ctgttcttaa cgttttgaga attgcgaagc
     1921 tttacgagct ttcttaagac ctggttgcat agctccctat ctcatatagt ttcaaaacgt
     1981 tgtgtttatt acactttacc aaagtgccgt catcaattat ttcactgaat ttgtatgaat
     2041 ttcaagtcaa acacggaaac tgttattctc ccttttggcc aatttcatca atcaatctat
     2101 ccaaaactcc ttgattgatg aagcactcta aatacgataa ctataccttt atcgaaacga
     2161 taatagatcg aatagttctt cactaacggt cgcctagcct tgattcccaa tacgagaact
     2221 caacgattga acatctatct gagaaaactt ctaaggtttg aatagcctct gcaatgttat
     2281 taaatagttt caatgcaacc tgagaggata gaggttcatc cgcaatataa caatagacat
     2341 catcaatgta ttcctcagca cgttttaaaa tatttaaaat gactttactc atgtgtgtcg
     2401 tttcctaaat tccttaaaac tgacagaagg tttccttact atccgtcttg tatttccgaa
     2461 aatgatgatt ttggaaaaat attacactca ttcctactaa agattttaat tgggtgatat
     2521 aaatagcagt gaactattga tacaaaatcc caaaaaattt cgaatagact tatgaggcaa
     2581 tagtctgctc gagataatga atcctcaaag ttttgctttc aaaagtataa aagtttttga
     2641 gctgatatct gttttaaaaa caacgtaatt ctaaaattcc cgatgcgcgt ttttttgacc
     2701 taatttttta tttgtaattg tagtacttca ctaaaaatga tagaatatag tagttaagga
     2761 gaaaaaatga caataccatc tatactcaat taccaaggaa ataaatcttc cttgatacca
     2821 tttttaaagc aaaatatcga aaaatattta gaaccaggag aaatattttt cgatattttt
     2881 tcagggtctg gaagtgttgg tgcaagtttc caacaagaaa atataatttt ttctaatgac
     2941 gctgaactgt attcaaccat tatttcttca tctcttttaa atactcccga agaaaccctt
     3001 ttacaggaaa ttgcagatca atttcagact caactaaaaa aaaatattaa caaaaattcg
     3061 attgaatata tagactatat aaaacaagag agagaattct tattatccca agataacgat
     3121 aaactaataa atctatataa aaatttccca acaatttgga ataagctaag aggagtcact
     3181 gtcaacaagt taagtaagca aagaaaatat aatttattta ctcattacta ctctggtact
     3241 tattttggaa tagagcaatc tatcattatt gatagtgtta ttgagacgat tcactctttt
     3301 caaaatgaat ccgtcacaga taccttatac agctgcttat tttttgcaat gaaagaaata
     3361 gtatttgcta aagatggaca catggcacaa ccattaaacc cctcaaaaaa tattacaaga
     3421 cattttaagc aaagatctaa aaatctcatt gatttactaa ataagaagct ggaggaattt
     3481 attctttata gctctaagaa ggttagtaat aaacaattcc aacatcaaat ctacaattta
     3541 gatattagag aaataactaa taataatctt ctggcaaact caaacataaa aatgatttat
     3601 gctgatcctc catacactga tatgcaatat tccagatatt accatttact caatgtagca
     3661 gcaagatatg actttccaga accaacaatt aatcacggta aatatacttc tggtctatac
     3721 accgaaggaa ggaatcaatc agacctaagt aaaaaaagta cggccaagaa tagaattgaa
     3781 gacctatgct tatactgtaa agaaaataat ataattctta cactaagtta tgcgtaccca
     3841 gaagaccaaa taaatcaaaa aatagataga tatactgttt ctatcgaaga tcttattgat
     3901 ttaacaaaaa aaattttcgg aagtagtaat gttaccattg ccgaggaaaa ttataagcac
     3961 gctaatcata ggaacagttc tacaaagaaa gttattgaat atttaatcat ttgtggtcct
     4021 ccttctacag aaaacgatca cccaaattcc ttgttaaatt taaaatatga cataaaaact
     4081 actatcccta cttcaaaaaa cccaatttat aatacacatc tatactggtc tcaaaaatca
     4141 tttaacataa tcgataaact tattcaacat ttatctaaag aaggggatac tattttcgat
     4201 ccgttcatgg gctcaggtgt tacaatctta gaaacaatta agaactcgct aaatcgtaaa
     4261 gcaattggat gtgacgtcaa cgaaatgcca agattcatag taacaaatat tattaataat
     4321 tttcaaaaaa aagaattagt tgaggtattc aataaactag aaaaaaaact ggatgaattg
     4381 acttcctact acactacaac ttgtacatca tgtaattccg aaaaagccat catctcaaaa
     4441 atagttttcg ataaaccttc aagaacaatc aatgattata atattaaggc ggttaactat
     4501 acctgtccaa attgcggtaa gaatactaag caggcagata ttaacgatga aaacaagatg
     4561 ctaagtctag tttgcagcga tcatattttc gatgaacaac tactaaaaaa cagtaaaata
     4621 gctgtgggag ataacgatca tctatctgac ttattcactc cccggaactt ctcgcttctt
     4681 aacgaaatcg ttggatatat ctcttcatca ggtgaccccg atatcctaaa ttatttgctc
     4741 atgtcgtgta ttcacctatg caaaattact gatttacact caaactctca atggccatta
     4801 tggattccga aaaaaaattg tgttgaaaaa aatatcattg atctactaaa gaaacgaata
     4861 aagaatatta ttaaagctac taactttgtt gaaaaaaatt atttaaactc ccatattgtt
     4921 tcggattata caaagcttac aacaaattct gctttagttt taacaaaagg tagtcaatat
     4981 attaccgaat acgaagtccc tgataactca attgacttaa ttatcacaga tcctccctac
     5041 aaagatcaag tattatattc tgagtatatg caattgtaca aacctattat tggtttggac
     5101 ttcaatttag aagacgaaat cgtagtctct ccttccccaa ttagaaaaag agcagaatca
     5161 gaatatttca atctactaaa ccaagtcttt gaattatgca gcaaaaaact aaaacagggt
     5221 tcattcatgt gcctattctt tcatgatagt aatttatctg tttgggctga attaataact
     5281 attctggaac acaatggctt taaatatatt tcacaggagc acattaaaaa atcaaaaacc
     5341 gtcaagaata taattagccc caaaaaatca ttatctggag atgctatcct attttttgaa
     5401 aatacaaaac acgagattaa aagctatgat accaatatat cagctgatga aatagcacac
     5461 tatatatact tggaatctaa aaaattacta gaatcaaaag gagaactctc tacacctgaa
     5521 ttatacgatt ttggtctgat ggaaatccta ataaataatg gttggttaga aatcctttct
     5581 agtaaatata aaaccttggt agatattttt gaagaaaaat ttatttggaa tagtgta
//
LOCUS       DATTYN010000053         4177 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.53, whole genome shotgun sequence.
ACCESSION   DATTYN010000053 DATTYN010000000
VERSION     DATTYN010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4177
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.53"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..641
                     /locus_tag="VB649_001783"
     CDS             <1..641
                     /locus_tag="VB649_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEP1670707.1"
                     /translation="LVGNYVHSYFESKEAHEEFKAQNGSEMISTRGTTKGQLKKDYLV
                     AEQMIGALKSDSNFMAIYQGEKEAAITGFLGGVEFKGKIDCLNVKRGYFVDIKTTKGP
                     IDDTIWNGEERVRWFEAYGYILQMAAYKTMLEAKYNKPFEPIIYAVTKETPPDTRAIR
                     IQNVDAMQIELDSLAQSIKRLDDVKKGIEKPKPCGKCEYCRQNKLSVRVEIF"
     gene            818..1159
                     /locus_tag="VB649_001784"
     CDS             818..1159
                     /locus_tag="VB649_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670708.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGSLTMQWDFISDFKKIDDE
                     PSLDEDGELFETAYDLILEAKPKTKINLTSSYFAKEHKKDTDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
     gene            1156..1668
                     /locus_tag="VB649_001785"
     CDS             1156..1668
                     /locus_tag="VB649_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670709.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLYQSGVLKHNSDSYFERGRY
                     MASQLRLIQSRALKKYDCRFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVA
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKEKALEYCGKTVKDDEADAILIGSYYVNQGY
                     LDGLETHDYY"
     gene            1845..2114
                     /locus_tag="VB649_001786"
     CDS             1845..2114
                     /locus_tag="VB649_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670710.1"
                     /translation="MTEEQMIDCLLYELVKKDKAIKKKSIIIAALTVMLIVVSGLCVS
                     LKSHYEKQIYGLRTQLSRTQKQLKRASEQNQRQTKRIAEMTGNGG"
     gene            2118..2600
                     /locus_tag="VB649_001787"
     CDS             2118..2600
                     /locus_tag="VB649_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP1670711.1"
                     /translation="MTDIKILDACCGSRLFWFDKNEPHTIFMDVRQEKFEMHGKKINV
                     NPDIIGDFRDMPFESNSFNLVVFDPPHLKYVGQNSIMKAQYGQLDKENWKEDISKGFQ
                     ECMRVLKVGGTLVFKWSDCQINVKEVLSAIPFKPLFGQQRGTTHWMTFVKFELTGNGG
                     "
     gene            2590..3354
                     /locus_tag="VB649_001788"
     CDS             2590..3354
                     /locus_tag="VB649_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEP1670712.1"
                     /translation="MGDSDVKCELYNDHFENAKRYNIPRAQLIIADIPYNLGNNAYAS
                     DPRWYENGSNKNGESKLAGKSFFDTDNDFKINNFFDFCSRLLRKEPKEKGKAPAMIVF
                     HSWQQREMVIQCGKKHGFKKAYPLYFIKKSSPQALKANMRIVGAVEEATVLYRDKLPK
                     FNNNGAMVLNHLPWEKDSFYPVIHPTQKPIPVLKRLIEIFTDPDDVVIDPVAGSGSTI
                     RAAIEMNRNAYGFEIKKDFYKRAKEEMLSTFQTSLF"
     gene            3402..3695
                     /locus_tag="VB649_001789"
     CDS             3402..3695
                     /locus_tag="VB649_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670713.1"
                     /translation="MNTNEKVIDTICHIRHYGDRYDMCQGMRSWIAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            3692..>4177
                     /locus_tag="VB649_001790"
     CDS             3692..>4177
                     /locus_tag="VB649_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEP1670714.1"
                     /translation="MNIKEAKIGDKVWVEGIINSSFSNGGVHVNHAGVDAFYDLERTK
                     IKPDGYAGQSPKYLKNIIAKMRELPEHDRAVWIKGIFKEFGIENDISYYLGHKQGVLQ
                     AKDSLKPEVPQYVADYIEKCKKRGDTLYLALKVEKSVKQSVYKWLWDGSGDESFIKFA
                     KA"
BASE COUNT         1500 a          688 c          901 g         1088 t
ORIGIN      
        1 tgctcgtcgg gaactatgtc cactcttact ttgagagtaa agaagctcat gaagaattca
       61 aagcccaaaa cggctctgaa atgatttcga ccagaggaac gacaaaaggt caattaaaaa
      121 aggactactt agtcgctgaa caaatgattg gcgctcttaa aagtgacagt aactttatgg
      181 ctatctacca aggggaaaag gaggcggcaa tcacaggatt tcttggcggt gtggaattta
      241 aaggtaaaat cgactgccta aacgtcaagc gtggctattt tgtagatatc aaaacaacaa
      301 aagggccgat tgacgacacg atttggaatg gcgaagagcg tgtcagatgg ttcgaggcct
      361 acggatatat cttgcagatg gccgcttaca aaaccatgtt agaagccaaa tacaataaac
      421 cgtttgaacc gattatttac gcagttacta aagagacacc accagataca agagccatca
      481 ggatccaaaa tgtagatgct atgcagatag agttagatag cctagcacaa agcattaagc
      541 gattagatga cgttaaaaaa ggcatagaaa agcctaagcc ttgtggaaaa tgcgaatatt
      601 gcagacaaaa taaattgtct gtaagggtag agatttttta ataacctatt gcaaagtgaa
      661 gctcggcctt tgcaagttta aattttccga gcgagaaagg aaagttggaa tatcgtcaag
      721 tcaacaggat tgatgatatg aagaattgct acactcgtcc ttgccaatgc tcacacacaa
      781 ttttagggcg agtgtggatt ttaaaaaggt gaaaaatatg gaacaaatca aaattacagg
      841 aacaggaaca gcactaattt tagatagagt aaaccgaatc tttgccatct ctggcagttt
      901 gactatgcaa tgggatttta ttagtgattt taaaaagatt gacgacgaac cgtcacttga
      961 tgaagatgga gagttattcg aaacagccta cgacctcatt cttgaagcta aacccaaaac
     1021 taaaatcaat ctaacatcat catattttgc taaagagcat aagaaagata cagacgaaat
     1081 cataaaagta ttctcattta tcgaagataa caagagaaat atctttgaaa cccttggcat
     1141 tcgcggggtg cttgaatgag caatctagtt ttatcgttag acatctcaac atctggaaca
     1201 gggtgggcct tatttaaagg ctcagacctg taccagagtg gtgtcttaaa acataatagc
     1261 gactcttact ttgaacgtgg gcgctacatg gctagtcaat taaggttgat ccagtcacga
     1321 gcattaaaaa aatacgattg ccgctttagc acaatcgcag ttgaaaaaaa ctcggttatg
     1381 ggacctaacc agcaatccat gcttaaaatc ggtattgtaa ctggtatcat cttaggacga
     1441 ttaatagctg ataatgtcgc ctttataaat gtatcaacat ggcgtaagca ctggaagttt
     1501 agctacaaag accgctctaa aaaagcgatg aaagcacaat cgaaagaaaa agctctcgaa
     1561 tattgcggaa aaacagtaaa agatgatgaa gcggatgcta ttttgattgg ctcatactat
     1621 gtcaatcaag gctatcttga tggattggag acacatgact actactaaaa aacacgttgt
     1681 gagagtttac aacaaaggta ttacagcgac ttacgcgatc tatgacaaaa aactgtttaa
     1741 ggagcacgag ttcgcaacca aaaacgaagc gatgcggttt attagacagc tagagttagc
     1801 tagcggcaag cgcgtaaacg agtattacat gaaggggtaa acggatgact gaagaacaga
     1861 tgattgattg cttgctttat gagttagtaa aaaaagacaa agcaatcaaa aagaaaagca
     1921 tcattatcgc tgcactaaca gttatgctga ttgtcgtatc agggctttgc gtatcactta
     1981 aaagtcacta tgaaaagcaa atatacggac tacgtacaca gctaagcagg acacaaaagc
     2041 agcttaaacg tgcgagtgag caaaatcaga gacagacaaa gcggattgcg gaaatgacag
     2101 gtaatggagg atagagaatg acagacatca agattttaga tgcttgttgt ggaagtcgcc
     2161 tattttggtt tgataaaaac gaacctcaca caatttttat ggacgtcaga caagaaaaat
     2221 ttgagatgca cggcaaaaaa atcaatgtca accctgatat aattggtgat tttcgtgata
     2281 tgccttttga aagtaatagc tttaaccttg ttgtcttcga tccaccacac ttaaaatatg
     2341 ttggacaaaa ctcaattatg aaagctcagt atggccaact tgataaagaa aactggaaag
     2401 aagatatttc aaaaggtttc caggagtgta tgcgagtttt aaaagtcggt ggcactttag
     2461 tttttaaatg gtctgattgt cagataaatg taaaggaagt tttatcagca ataccattta
     2521 agccactttt tggccagcaa agaggcacta cacactggat gacatttgtt aaatttgaac
     2581 ttactggaaa tgggggatag tgatgtgaaa tgcgaattgt ataatgatca ttttgagaac
     2641 gctaaacgtt acaacatacc aagagcgcaa ttaattattg cggatattcc ttataactta
     2701 ggcaataatg cctatgcgag cgacccgcgt tggtacgaaa atggaagcaa caaaaatggc
     2761 gaaagtaaac tagcaggtaa atcatttttt gatacagaca atgattttaa aatcaataat
     2821 ttctttgatt tttgtagccg tctcttacga aaagagccaa aggaaaaagg aaaagcgcca
     2881 gcaatgattg tttttcattc atggcaacaa agagaaatgg ttatccaatg tggtaaaaag
     2941 catggtttca agaaagctta tccgctttat tttatcaaga agtccagtcc acaggccttg
     3001 aaagcgaaca tgaggattgt tggagcggtt gaggaggcga cagtattata tcgggataaa
     3061 ttacctaaat ttaataataa tggcgcaatg gttttaaatc atttaccatg ggaaaaagat
     3121 agcttctatc cagttattca tccaacacaa aaaccaatac ccgttttaaa aagattaatt
     3181 gagattttca cagatcctga tgatgtggtt attgatcctg ttgctggaag cggatcaaca
     3241 attcgtgcag caatcgaaat gaatagaaat gcttatggat ttgaaataaa aaaagatttt
     3301 tataagagag cgaaggaaga aatgcttagt acgtttcaaa ccagtctttt ttgaaaaagg
     3361 aattcaaact gatatttata attttttaag cgaggtacaa aatgaacact aacgaaaagg
     3421 taatcgatac tatatgtcac atcagacact acggtgacag atacgatatg tgccagggca
     3481 tgcgatcgtg gatagctgag agaaatggat taatccagga cttactcaaa gcaaaaaaac
     3541 aaattgatcg caatcgtatc gctaaacgtc tggatcgtgc gcagaaaaac atcagtgaca
     3601 ttatcacaaa agtgacaggc gacttatggc aaggcagtga tcaagtcatt gctgagcagt
     3661 gttttttaaa agtattagag gagatgcaaa aatgaacatt aaagaagcga aaataggcga
     3721 taaagtgtgg gttgaaggta ttatcaattc gtccttttca aatggtggag tacatgtaaa
     3781 tcatgctggt gttgacgcct tttatgatct tgagcgaaca aaaataaaac cagacggata
     3841 cgcagggcag tcacctaaat atcttaaaaa tattattgct aaaatgcgag aactaccaga
     3901 gcacgacaga gccgtctgga ttaaaggtat ttttaaggaa tttggtattg agaacgacat
     3961 tagctattat cttggccaca agcaaggcgt attacaagca aaggattcgc taaaaccaga
     4021 agtaccgcag tatgtggctg actatataga aaagtgcaag aaaagaggcg acacattata
     4081 cttagcgtta aaagtcgaaa aatctgtaaa acaatctgta tataagtggt tatgggatgg
     4141 cagcggtgat gagagtttta ttaagtttgc taaagct
//
LOCUS       DATTYN010000054         4047 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.54, whole genome shotgun sequence.
ACCESSION   DATTYN010000054 DATTYN010000000
VERSION     DATTYN010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4047
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.54"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            122..460
                     /locus_tag="VB649_001791"
     CDS             122..460
                     /locus_tag="VB649_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HEP1670715.1"
                     /translation="MKPPFTVTNTMLNKVVEISKIIGNLELQVQKDLKLRKENRIQSI
                     HSSLAIEQNSLTVEQITAIIDGKRVLGNPREIREVKNAYEAYEEILTLTPYDESHFLK
                     MKEFQQYIYR"
     gene            484..1308
                     /locus_tag="VB649_001792"
     CDS             484..1308
                     /locus_tag="VB649_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine ligase"
                     /protein_id="HEP1670716.1"
                     /translation="MGLGSDSLPVKISLFDVDTYLADSMQFHLEYILRLFPKSGVHYL
                     MPTFRGEAVDHRHLLQFYHSECEIEGDLHYVMNLVDRYIKFLVSEILRECRDSIFAIT
                     KDVSHLESFIDRKIPIITFEEACTILENEIDSLEYNDEHHFYVLTDVGEKKLMEHFEG
                     VVWVKNYPCKSVPFYQRFSTDHLFAYNADLLLGIGETVGCGERCETYEEVVENMNYLQ
                     VDASEYSWYLEMKKTRPMKSSGFGLGVERLIAWILKCDDVRKVQLISRENGIDYLP"
     gene            1322..2569
                     /locus_tag="VB649_001793"
     CDS             1322..2569
                     /locus_tag="VB649_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit family protein"
                     /protein_id="HEP1670717.1"
                     /translation="MKKNILIVGGGPEITICYDLINNSTEYNFFSVSEIPTMYPELFV
                     ETIETSFRNFGKTIEQIKELKYSIDAVACWDEALTHIADDISKELGLNPISSLDSQSF
                     RFKDRMRMVCEAGGLKMPKYKIINQFSDTNKIINWKYPLIVKPTSFLASIGVKKVYNF
                     SELQQAVSQMLNVKFPVYIASGVYELGELYNLEPRVLVEEFIDGEEYSLESVVRNGIY
                     TPLGITKKIVDEKLFMDEIGHIFPSNLNKEEKSRVYSWAEKLHQILQLNHITTHTEFR
                     IGRNGDIILIEIGARIGGDCIPNLMKNSFIVKGFDFYNTYLKARLGLQEELNTDTNKF
                     SGIVFFRLNPENYGKIFNGVSYDAPKTSLIFEEKIYKKEGTVLPNPINWSNERVGYIC
                     LENKEYAVLEKEMKEILKSLSIE"
     gene            2494..3513
                     /locus_tag="VB649_001794"
     CDS             2494..3513
                     /locus_tag="VB649_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEP1670718.1"
                     /translation="MFGKQGIRCARKGDERNIKIIVNRVNSERNIKSIGICSPSYPGT
                     FHYQKRYKRGVEFLQNKGFTIVEGNLTGKEGYRGEISGGVQDRAEELNQLIPRVDVIM
                     TSIGGYNSNSVLKYIDYDLFKQKSPIFIGYSDTTALALALYKKTGCITYLSQSVISNF
                     GEFEPFNELNYFYFDFMLQSKCETLMVQIPDVWTDEWINWETYERTKKTNKNEWIIFN
                     KGEFNGTLIGGNLDTIVGIIGTEYMPKITEDTILLLEDVYTDLGRLYRNFTTLALHGI
                     FDKIGGLIISKFETIGENSDVINDIINEFVGHRKIPILLNFDCGHTHPSCLMPIGGKI
                     TLSLS"
     gene            3588..>4047
                     /locus_tag="VB649_001795"
     CDS             3588..>4047
                     /locus_tag="VB649_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HEP1670719.1"
                     /translation="MNHIHNVFVEESEKFGFQQMKTAMVEHRKKYLDATDVHYTKIFE
                     VHRVKEESVYALQSDLALSMSRCIANLPQQIPVKWIQEGVLFRDRIPTYKGYRRQFNQ
                     ILLGAWGIESAYVDAEIIVATWRGLQRFKGIKVEFIQLSNKNIFDVLEKDL"
BASE COUNT         1517 a          470 c          796 g         1264 t
ORIGIN      
        1 gtaatcgtta aagaatttaa aataaattgt aatagtttat cgcttgtttt atcgcttgaa
       61 gaacgagcga taaatttatt tttatggtat aaataagaaa aaagattgta aggagaaaat
      121 gatgaaacca ccttttacag ttacgaatac catgttaaat aaggtagtag agatttctaa
      181 aattattggt aatttagaat tacaagtaca gaaagattta aaattaagaa aagaaaatcg
      241 tattcagtct attcactcat cactcgctat tgaacaaaat tctttaacag tagaacaaat
      301 aacagccatt attgatggga aaagagtgtt agggaacccc cgtgagataa gagaagtaaa
      361 aaacgcttat gaagcttatg aagaaatttt aacgctaact ccctatgatg aatcacattt
      421 tttaaaaatg aaggaatttc aacagtacat ttaccgataa caacatcgtc aatcacaagt
      481 cctatggggt tggggagtga ttcgctacct gtaaaaattt ccttatttga tgttgatacc
      541 tatcttgcag attcgatgca gtttcactta gagtatatac ttagactttt tccaaagtca
      601 ggagttcatt acttaatgcc tacttttaga ggagaagcag tagatcatcg acatttattg
      661 caattttatc atagtgagtg tgagatagag ggagatttac actatgtgat gaatttagtg
      721 gatagatata ttaagtttct ggttagtgaa attcttagag agtgtcgaga tagtattttt
      781 gctataacaa aagatgtaag tcatttggaa agttttattg atcgaaagat accaattatt
      841 acgtttgaag aggcttgtac tatattggaa aatgaaatag attcattgga atataatgat
      901 gaacatcatt tttatgtgtt aacagatgtt ggggaaaaga aattaatgga acattttgag
      961 ggagtagttt gggtaaaaaa ttatccctgt aaaagtgtcc ctttttatca aaggttctca
     1021 acagatcatc tatttgccta taatgcagat ttgttgttag gaataggcga aactgtaggt
     1081 tgtggagaaa gatgcgaaac atatgaagaa gttgtagaaa atatgaatta tttacaagta
     1141 gatgcttctg aatatagttg gtatttagaa atgaaaaaaa caagacctat gaaatcttca
     1201 ggatttggtt taggagtaga gcgtttaata gcgtggatat tgaagtgcga tgatgttcga
     1261 aaagttcaat taatcagtag agaaaatggg attgattatt taccataaag gaggaagaaa
     1321 aatgaaaaag aatattttaa ttgtaggtgg aggtccagag ataactatat gttatgattt
     1381 aattaacaat agtacggagt ataatttctt ttcagtatca gaaattccta cgatgtatcc
     1441 agagttgttt gtagaaacaa ttgaaaccag ctttagaaat tttggaaaga cgattgaaca
     1501 aattaaagag ctcaaatatt ctattgatgc tgttgcttgt tgggatgaag ctttaacgca
     1561 tatagctgat gatatttcaa aagaattagg attgaaccct atttcatcgc tagattctca
     1621 atcattcagg tttaaagatc gaatgagaat ggtatgtgaa gctggtggac taaaaatgcc
     1681 caaatataaa attatcaatc aattttcaga tacaaataaa ataatcaatt ggaaatatcc
     1741 attaatagtg aaaccaacct cttttttagc aagtatagga gtgaaaaaag tttataattt
     1801 ttcagaatta caacaagcag tttctcaaat gcttaatgta aaatttccgg tttacatagc
     1861 ttcaggggta tatgaattgg gggaattata taatttagaa cctagagttt tggtggaaga
     1921 gtttattgat ggagaagaat atagcttaga gagcgtggta agaaatggaa tctatacacc
     1981 tctagggata actaaaaaaa tagtggatga aaaattattt atggatgaaa taggccatat
     2041 tttcccttca aatttaaaca aagaagaaaa aagtagagta tattcctggg cagaaaaatt
     2101 acatcaaatt ttgcaattaa atcatattac gactcataca gaatttagaa ttggaagaaa
     2161 tggagatatt attttaatag aaattggagc aagaatcggt ggagattgta ttccaaactt
     2221 aatgaaaaac agctttatag tcaagggatt tgatttttat aatacttatt taaaagctag
     2281 actaggttta caagaagagt taaatacaga cactaataag ttttcaggaa ttgtattttt
     2341 cagactcaat ccagagaatt acggaaaaat atttaatgga gtgagttacg atgcacctaa
     2401 aacttcacta atatttgaag aaaagatata taaaaaggaa ggaactgtat tgccaaatcc
     2461 gattaattgg agtaatgaga gagtaggata tatctgtttg gaaaacaagg aatacgctgt
     2521 gctagaaaag gagatgaaag aaatattaaa atcattgtca atagagtaaa tagtgaaaga
     2581 aacatcaaat ctataggtat ttgttcaccc tcctatccgg ggacatttca ttatcagaaa
     2641 cgatataaga gaggagtaga atttttacaa aataaaggat ttactatagt agagggaaat
     2701 ttaacaggaa aagaaggtta tagaggggaa atttcaggag gagttcaaga cagagctgaa
     2761 gaattaaatc aacttattcc gcgtgtggat gtcatcatga cttccatagg tggctacaat
     2821 tctaattctg tattaaagta tatagactac gatctattta aacagaaatc tcctatcttt
     2881 attggatatt ctgacacaac agctcttgct ttagccttat ataaaaagac tggatgtata
     2941 acttacctgt ctcagagcgt tatctctaat tttggagagt ttgaaccgtt taatgaatta
     3001 aattatttct attttgactt catgcttcag agtaagtgcg aaaccttaat ggtacaaata
     3061 ccagatgttt ggacggatga gtggataaat tgggaaacct atgaaagaac caaaaaaaca
     3121 aataaaaatg agtggattat ttttaacaaa ggtgaattta atggtacttt gatcggagga
     3181 aatctcgata ccattgtagg aataatagga actgagtata tgccaaaaat aacagaggat
     3241 accatactct tgttagaaga tgtatatacg gatctaggaa gactatatag gaatttcaca
     3301 acgcttgcct tacatggtat ttttgataaa ataggaggac ttattatttc aaaatttgaa
     3361 acaatagggg aaaatagcga tgttattaat gatatcatta atgaatttgt agggcataga
     3421 aagattccta ttttattgaa ttttgattgt ggtcatactc atcctagctg tttaatgcct
     3481 attggtggta aaattacgtt gagtttaagc taaaagaggt ggtatatgaa caatagagaa
     3541 agtaaattaa cgggtttcta tgatgttttg aggaagaagt agaaaaaata aatcatattc
     3601 ataatgtttt tgtagaggag tcagaaaaat ttggctttca acagatgaag actgctatgg
     3661 tagagcatag aaaaaaatac ttagatgcaa ccgatgttca ttatacaaaa atatttgaag
     3721 ttcatagagt aaaagaagag tcagtatacg ccctccaatc agatttggca cttagtatgt
     3781 cgcgttgtat agctaactta ccacaacaaa tacctgtaaa gtggattcaa gagggagtgt
     3841 tatttagaga tagaattcct acatataaag gttatagaag acaatttaat caaatattat
     3901 taggtgcatg gggaatagaa tcagcttatg tggatgcaga aataatagtt gcaacttggc
     3961 gaggcttgca gcgatttaaa ggaattaaag tagaatttat tcaactgtct aacaaaaata
     4021 tatttgatgt tttggagaaa gatttat
//
LOCUS       DATTYN010000055         4023 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.55, whole genome shotgun sequence.
ACCESSION   DATTYN010000055 DATTYN010000000
VERSION     DATTYN010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4023
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.55"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            101..1649
                     /locus_tag="VB649_001796"
     rRNA            101..1649
                     /locus_tag="VB649_001796"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1701..1773
                     /locus_tag="VB649_001797"
     tRNA            1701..1773
                     /locus_tag="VB649_001797"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1734..1736,aa:Ala,seq:tgc)
     gene            2072..>4023
                     /locus_tag="VB649_001798"
     rRNA            2072..>4023
                     /locus_tag="VB649_001798"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1166 a          819 c         1155 g          883 t
ORIGIN      
        1 agacgaacca aacgtgaggg tgatatggag acatattacc cgtcaagaaa cgagaaataa
       61 atctgtcagc gacagaagga acgagtaagt tcaaacgcaa attaaagaga gtttgatcct
      121 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gagaactggt
      181 gcttgcaccg gttcaaggag ttgcgaacgg gtgagtaacg cgtaggtaac ctacctcata
      241 gcgggggata actattggaa acgatagcta ataccgcata agagagacta acgcatgtta
      301 gtaatttaaa aggggcaatt gctccactat gagatggacc tgcgttgtat tagctagttg
      361 gtgaggtaaa ggctcaccaa ggcgacgata catagccgac ctgagagggt gatcggccac
      421 actgggactg agacacggcc cagactccta cgggaggcag cagtagggaa tcttcggcaa
      481 tgggggcaac cctgaccgag caacgccgcg tgagtgaaga aggttttcgg atcgtaaagc
      541 tctgttgtta gagaagaatg atggtgggag tggaaaatcc accaagtgac ggtaactaac
      601 cagaaaggga cggctaacta cgtgccagca gccgcggtaa tacgtaggtc ccgagcgttg
      661 tccggattta ttgggcgtaa agcgagcgca ggcggttttt taagtctgaa gttaaaggca
      721 ttggctcaac caatgtacgc tttggaaact ggagaacttg agtgcagaag gggagagtgg
      781 aattccatgt gtagcggtga aatgcgtaga tatatggagg aacaccggtg gcgaaagcgg
      841 ctctctggtc tgtaactgac gctgaggctc gaaagcgtgg ggagcaaaca ggattagata
      901 ccctggtagt ccacgccgta aacgatgagt gctaggtgtt aggccctttc cggggcttag
      961 tgccggagct aacgcattaa gcactccgcc tggggagtac gaccgcaagg ttgaaactca
     1021 aaggaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg aagcaacgcg
     1081 aagaacctta ccaggtcttg acatcccgat gcccgctcta gagatagagt tttacttcgg
     1141 tacatcggtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa
     1201 gtcccgcaac gagcgcaacc cctattgtta gttgccatca ttaagttggg cactctagcg
     1261 agactgccgg taataaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat
     1321 gacctgggct acacacgtgc tacaatggtt ggtacaacga gtcgcaagcc ggtgacggca
     1381 agctaatctc ttaaagccaa tctcagttcg gattgtaggc tgcaactcgc ctacatgaag
     1441 tcggaatcgc tagtaatcgc ggatcagcac gccgcggtga atacgttccc gggccttgta
     1501 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gtcggtgagg taacctatta
     1561 ggagccagcc gcctaaggtg ggatagatga ttggggtgaa gtcgtaacaa ggtagccgta
     1621 tcggaaggtg cggctggatc acctcctttc taaggaaatg gaacacgttt atcgtcttat
     1681 ttagttttga gaggtcttgt ggggccttag ctcagctggg agagcgcctg ctttgcacgc
     1741 aggaggtcag cggttcgatc ccgctaggct ccatcaggat acaatcctac taaacttaat
     1801 acaagtgaag ttgaacacgc aactcacttc ctaggaaaat agacaatctt cgcttgtgtg
     1861 caaggcccac atggtcagat tcctaatttt ctacagaagt ttcgctaaag cgagcgttgc
     1921 ttagtatcct atataatagt ccattgaaaa ttgaatatct atatcaaatt ccacgatcta
     1981 gaaatagatt gtagaaaagt aacaagaaaa taaaccgaaa acgctgtgat tatttaataa
     2041 gttttctagt ttaaaaaaac taggttaata aggttaagtt aataagggcg cacggtggat
     2101 gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt ggggagctgt
     2161 aagtaagcgc tgatccagag atgtccgaat gggggaaccc actaactaat ggttagtatc
     2221 cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta agtagctgca
     2281 ggaagagaaa gcaaacgcga ttgccttagt agcggcgagc gaaacggcag gagggcaaac
     2341 cgaagtgttt acacttcggg gttgtaggac tgcgacgtgg gactttaaaa ggatagaaga
     2401 attacctggg aaggtaagcc aaagagagta acagcctcgt atttaaaatt cttttgagcc
     2461 ctagcagtat cctgagtacg gcgagacacg tgaaatctcg ttggaatctg ggaggaccat
     2521 ctcccaaccc taaatactct ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg
     2581 aaaagcaccc cgggagggga gtgaaataga acctgaaacc gtgtgcctac aacaagttcg
     2641 agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt acgatatgat
     2701 gcgaggttaa gttgaagaga cggagccgta gggaaaccga gtcttaatag ggcgatttag
     2761 tatcatgttg tagacccgaa accatgtgac ctacccatga gcaggttgaa ggtgaggtaa
     2821 aactcactgg aggaccgaac cagggcacgt tgaaaagtgc ttggatgact tgtgggtagc
     2881 ggagaaattc caaacgaact tggagatagc tggttctctc cgaaatagct ttagggctag
     2941 cgtcgatgtt aagtctcttg gaggtagagc actgtttggg tgaggggtcc atctcggatt
     3001 accaatctca gataaactcc gaatgccaac gagatatcat cggcagtcag actgcgagtg
     3061 ctaagatccg tagtcgaaag ggaaacagcc cagaccacca gctaaggtcc caaaataact
     3121 gttaagtgga aaaggatgtg gggttgcaca gacaactagg atgttagctt agaagcagct
     3181 attcattcaa agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc
     3241 ggggctaaaa cagtttaccg aagctgtgga tgacacaaaa gtgtcatggt aggagagcgt
     3301 tctatgtgtg aagaaggtgt accgtgagga gcgctggaac gcatagaagt gagaatgccg
     3361 gtatgagtag cgaaagacag gtgagaatcc tgtccaccgt aagactaagg tttccagggg
     3421 aaggctcgtc cgccctgggt tagtcgggac ctaaggagag accgaaaggt gtatccgatg
     3481 gccaacaggt tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa
     3541 ctaaaccgga cgattggaag agtccggcta agcagtgagg tgtaagatga gtcaaatgct
     3601 tatctttata acattgagct gtgatgggga gcgaatttta gtagcgaagt tagtgatgtc
     3661 acactgccaa gaaaagcttc tagcgtttaa tgatactcta cccgtaccgc aaaccgacac
     3721 aggtagtcga ggcgagtagc ctcaggtgat cgagagaact ctcgttaagg aactcggcaa
     3781 aatgaccccg taacttcggg agaaggggtg ctgacttagg tcagccgcag tgaataggcc
     3841 caagcaactg tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg
     3901 tgacgcctgc ccggtgctgg aaggttaaga ggagggttta gcgcaagcga agatctgaat
     3961 tgaagcccca gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt
     4021 cgg
//
LOCUS       DATTYN010000056         3564 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.56, whole genome shotgun sequence.
ACCESSION   DATTYN010000056 DATTYN010000000
VERSION     DATTYN010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3564
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.56"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            59..2212
                     /locus_tag="VB649_001799"
     CDS             59..2212
                     /locus_tag="VB649_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEP1670720.1"
                     /translation="MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKT
                     NKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDVPYPFIVHVNKEGKFQHYYVVYQ
                     NKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
                     IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYIL
                     QQMMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANAII
                     DALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIVIIFIFMHPFEKMNN
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQS
                     SLKQGAQLILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQS
                     AKVANNRLNEVYLVDSEFQEAGTLVNQELLHGDIQFEELSYKYGFGRDTLSNINLTIK
                     QGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHINYLPQQ
                     AYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISA
                     RTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS"
     gene            2223..>3564
                     /locus_tag="VB649_001800"
     CDS             2223..>3564
                     /locus_tag="VB649_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEP1670721.1"
                     /translation="MNPNLFKSAEFYHRRHHNFATFLILPSVLLVSFLVIFALFAKKE
                     ITITSQGELTPTKVIASVQSTSDHTIVVNNLKNNKFIKKGDVIIQYSKTMENSQKKAL
                     EKRLATLNKQKNGLQILRTSLEQETNLFKGEDEFGYSDTFNHFLKQTQDIIIGIAKKN
                     AEINNQASLANHAISVITSQLDELHQKITDYEELKQAINNQEYKLSPENPHQTALKKY
                     QTQFQAQEDNSALKEEYLSQIPQNISELESSMANLSIQRASTGNFSLPDTSHRIKIDI
                     LKTQFLQNASQQLTTVENQITELKNQIEQANIQLKNNIIIAPETGTIHLNSEFEGKSL
                     IPNGSEVAQIYPDIQKIKEVFITYYVTSEHVSLLKEKQGVRLSLEKVGNQTLTINGTI
                     QTIDKSATKTNQGNLFKVTALSKLSNKDSDVVQYGLQGRVTSVITRKSYFNYYKD"
BASE COUNT         1229 a          664 c          575 g         1096 t
ORIGIN      
        1 aaaactccct atatatatgt cataatagct tagtatttaa tagaaaggtc ttttacaaat
       61 gatatcctat cgaaaaacat ttgttgctca gattgatgct agagactgtg gtgtggctgc
      121 tcttgcttcc atcgctaaat attacggttc agactactct ttagctcatt taagagagtt
      181 agctaaaaca aataaagagg gaacaacagc gcttggcatc gtcaaagctg ccaaattaat
      241 gggatttgaa acaagagcta ttcaagcaga catgaccctc tttgatatag aagatgtccc
      301 ttatcctttt attgttcatg ttaataaaga aggtaaattc caacactact atgtcgtcta
      361 tcaaaacaaa aaaaattatc tgataatcgg cgaccctgac ccgacagtaa aagtcactaa
      421 gatgacaaag gagcgattta cttctgaatg gacgggtgtc gctatttttc tagcacccga
      481 gcccagctac aagcctcata aggacaaaaa gaacggtcta ataagctttt tacctctcat
      541 ttttaaacag cgatctctga ttttctatat catattagct agcctactcg ttactctgat
      601 taatattgta ggttcttatt acctacaagg tatattagat gactatattc caaatcaact
      661 gaaatcaaca ctcggcatta tttcaattgg tcttatcatt acctatatcc tccaacagat
      721 gatgagtttt tcgcgagatt atctcctgac tgtactgagt cagcgattaa gcattgacgt
      781 cattttatct tacattcgcc atatttttga gcttcccatg tctttttttg caactcgcag
      841 aacaggagaa atcatctcac gttttacaga tgctaatgct attattgatg cactcgcttc
      901 tactattttg tctctttttc ttgatgtcag tattttaact atcgtaggga cagttctgtt
      961 agtgcaaaat accaatcttt ttcttctatc tctggtttca gtccctctat atattgttat
     1021 tatctttata tttatgcacc catttgaaaa gatgaataat gatgtcatgc agagtaactc
     1081 tatggttagc tcagccatta tcgaagatat caatggcatt gaaactatta aatcactgac
     1141 cagtgaagaa aatcgttatc agaaaattga tagtgaattt gtggactatc tggataaatc
     1201 cttcaagtta agtaagtact ctattttaca aagcagtctc aaacaagggg cgcaactaat
     1261 ccttaacgtg atagtcttat ggtttggggc caaattagtt atgggaggaa aaatttctgt
     1321 tggtcagttg attacgttta atactctctt atcttatttt accaatcctt tagaaaatat
     1381 cattaatctt caaactaaac tgcaatcagc caaggtagct aataatcgtc tcaatgaagt
     1441 ttacctagtc gattctgagt ttcaagaggc tgggacatta gtcaatcaag aattattaca
     1501 cggagacatt caatttgaag agttatccta taaatatggc tttggacgcg atactctgtc
     1561 aaatattaat ctcactatta agcaagggga caaagttagc cttgttggta ttagtggatc
     1621 tggtaaaacg actctagcta aaatgattgt taattttttt gagccttata acggccgaat
     1681 taccattaat cataatgact taaaaatgat tgataaaaaa agtcttcgcc aacatattaa
     1741 ttatctcccc caacaagcct atatttttaa tggttctatt ttagaaaatt taaccttagg
     1801 tgctaatgac tgtactagtc atgaagatat tctaagagct tgtgaggttg cagaaattcg
     1861 acaagatatt gaacaaatgc ctatgggcta tcaaacagag ctttctgatg gtgccggact
     1921 ctcaggaggc caaaagcaac gaattgcact tgccagagct ctcctaacca aggcgcctgt
     1981 gcttattcta gatgaggcta caagcggtct tgacgtacta actgaaaaga gggttattga
     2041 taatcttttg gctatgacgg ataaaactat tattttcgta gctcatcgtc tcagcatttc
     2101 agcgcggacc aatcaagtca ttgtgcttga tgagggtaaa attattgaaa taggatctca
     2161 tcaagaatta atgactaaac aaggtttcta tcatcattta tttagtagtt aaggagaata
     2221 acatgaatcc aaaccttttt aaaagtgcgg aattttatca tcgacgtcat cataactttg
     2281 caactttctt gattttgcca tccgttttgt tagtgagctt cttagttatt tttgctctct
     2341 ttgctaaaaa agaaattacc attacttcac aaggagaatt gacgccaaca aaagttattg
     2401 cttcagtcca atcaactagt gaccatacta ttgtcgtcaa caatttaaaa aacaataaat
     2461 ttattaagaa aggtgatgtt attatccaat actcaaaaac aatggaaaat tctcaaaaaa
     2521 aagctttaga aaaacgatta gccactctta acaaacaaaa aaatggactc caaatactca
     2581 gaaccagtct agaacaagaa actaacttat ttaagggaga agatgaattc ggctatagcg
     2641 atacgtttaa tcattttctc aaacaaaccc aagatataat cattgggatt gctaaaaaaa
     2701 atgctgaaat caataatcaa gcaagtcttg ctaatcatgc catttcagtt atcactagtc
     2761 agcttgacga acttcatcaa aaaattacag attatgaaga gctaaagcaa gctattaata
     2821 atcaagaata taagctttca cctgagaatc cacatcaaac tgccctaaaa aaatatcaaa
     2881 ctcaatttca agcacaagaa gataactcag ctttaaaaga agaatacctt tctcaaatcc
     2941 cacaaaatat ctcagaactt gaatcttcaa tggcaaacct tagtatccaa cgtgctagta
     3001 caggaaattt ttctcttcca gacactagtc ataggatcaa aatagatatt ttaaaaacac
     3061 aatttctgca aaatgcttcc caacaactta ccacagttga aaatcaaatt actgaactta
     3121 aaaatcaaat tgagcaagcc aatattcagc taaagaacaa tataattata gctcctgaaa
     3181 caggaacgat acatctaaac agtgaatttg aagggaaatc tctcattcct aatggaagtg
     3241 aggtggctca aatctaccca gatatccaaa aaataaagga agtattcatt acctactacg
     3301 tcacttcaga gcatgtctca ttgttaaaag aaaagcaagg tgttcgtctt agtcttgaaa
     3361 aagttggaaa ccaaactcta acaattaacg gaacgattca gactattgat aaatctgcca
     3421 caaagactaa tcaaggtaat ctcttcaagg ttactgcact ctccaaactt tctaataaag
     3481 acagtgacgt cgtacagtat ggattgcaag gacgtgtaac aagtgtcatt acacggaaaa
     3541 gctatttcaa ttactataaa gata
//
LOCUS       DATTYN010000057         3539 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.57, whole genome shotgun sequence.
ACCESSION   DATTYN010000057 DATTYN010000000
VERSION     DATTYN010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3539
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.57"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(<1..279)
                     /locus_tag="VB649_001801"
     CDS             complement(<1..279)
                     /locus_tag="VB649_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670722.1"
                     /translation="MKSYLCSNFLKIKNTSYLLIHILAALLFPLLLFFYWSQRGGLQS
                     RTVLFSYFQIVGVLLPFVASIVCIQLKNLEESSGKYKYLLGYSQSNYKP"
     gene            complement(282..1031)
                     /locus_tag="VB649_001802"
     CDS             complement(282..1031)
                     /locus_tag="VB649_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HEP1670723.1"
                     /translation="MVQIFLSNLLKIKNTSISKLILIFPIICVMLSLLFSALGGENIL
                     RLTAETTVNQWGVIWINVIIAVNSGLLNKLELDSNKYSVFLSRDVDLKKVEYARVLLI
                     ALINLIISMILSLMLIVISFVLPTPSLISIGRILLTILLIWLTTLWQIPFILWLSRKI
                     NVYFAMIINIISPLIIGTSFSLLNKWYLFPYDWSLKLLEPMTRMRINSIPFGAEFVPD
                     YSQIFISLFLGIAFFILLTNLFAISFKKQVK"
     gene            complement(1037..1726)
                     /locus_tag="VB649_001803"
     CDS             complement(1037..1726)
                     /locus_tag="VB649_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HEP1670724.1"
                     /translation="MLKIQNLKKSYGKRTILNNVNMNIPKGKVYALIGPNGAGKSTIM
                     KILTGLVSKTSGSIIFEGREWSRRDLRKIGSIIEEPPLYKNLSAYDNMKVVTTMLGVS
                     ESTILPLLNKVGLGNIDKRPVKQFSLGMKQRLGIAISLINSPKLLILDEPTNGLDPIG
                     IQELREIIESFKSEGMTIMISSHILSEVEHLADFIGFIYEGKIILEKEYDGSENLEEL
                     FNNQILFEKRR"
     gene            complement(1808..2427)
                     /locus_tag="VB649_001804"
                     /pseudo
     CDS             complement(1808..2427)
                     /locus_tag="VB649_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922273.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(2542..2682)
                     /locus_tag="VB649_001805"
     CDS             complement(2542..2682)
                     /locus_tag="VB649_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic streptin"
                     /protein_id="HEP1670725.1"
                     /translation="MNNTIKDFDLDLKTNKKDTATPYVGSRYLCTPGSCWKLVCFTTT
                     VK"
     gene            complement(2830..>3539)
                     /locus_tag="VB649_001806"
     CDS             complement(2830..>3539)
                     /locus_tag="VB649_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEP1670726.1"
                     /translation="NLKSLIEREILEKQDLSFQIAALSHDIKTPLTVLKGNLELLELT
                     TLNKNQEGYIVSMNNSISVFEGYFNSLISYTRMLSEDRSVKLILVEELLSELHFEVDD
                     LLNINNIEFSICNRLIITSFYGDEENLIRALSNLLVNAIRFMPVLDKKIEVILSESGE
                     QIHFEIWNNGERFSDSTLKKGDKLFYTEDYSRGNKHYGIGLAFVKGVAIKHGGNLQLN
                     NPARGGASAIISIKKKI"
BASE COUNT         1239 a          630 c          440 g         1230 t
ORIGIN      
        1 tggcttataa ttcgactgtg agtaacccaa taaatattta tattttccag atgattcttc
       61 caaatttttt agttgaatgc acacaatact tgcaacaaaa ggaagaagta cacctactat
      121 ttgaaagtag gagaataata cagtcctgct ttgtaaacct ccacgttgac tccaatagaa
      181 aaatagaagt aagggaaata atagtgcagc taaaatatgt attagtaaat atgaagtatt
      241 tttgattttt aaaaaattag aacataaata tgatttcatg actatttcac ctgttttttg
      301 aaagagatag caaatagatt ggtcagtaag atgaaaaaag caattcctag gaacaatgat
      361 ataaaaatct gtgagtagtc tggaacaaac tccgctccaa aaggtatact atttattctc
      421 attcttgtca ttggctcaag caacttcaac gaccaatcat aagggaacaa ataccattta
      481 tttaagagag aaaaacttgt accaataatt agtggagata taatattaat aatcatagca
      541 aaatacacat taatttttct tgatagccat aaaataaacg ggatttgcca tagtgtagtc
      601 aaccaaatta acaagatagt taatagtatc ctacctatac taataagact tggagtaggt
      661 aggacaaaac taattacaat aagcattaag cttaaaatca tactaattat tagatttata
      721 agagctatca atagaactct ggcatattct acctttttta aatcaacatc ccttgataaa
      781 aaaacagaat acttattaga atctaattct aatttattta acaaaccaga atttacagca
      841 ataataacat taatccaaat aactccccac tgatttactg ttgtttccgc agttaaacgt
      901 aggatatttt caccacctaa tgctgaaaac aataaagata acatcacaca aataataggg
      961 aaaataagaa tcaacttgct aatactcgta ttttttattt ttaataaatt tgataaaaaa
     1021 atttgtacca tagcccctac ctcctctttt caaataaaat ttgattattg aataactctt
     1081 caagattctc agagccgtca tattcttttt ccagaataat ctttccttca tagataaatc
     1141 caataaaatc agctagatgt tcaacttctg acagtatatg gcttgaaatc ataattgtca
     1201 ttccttctga tttaaatgac tctataattt cccttaattc ttgaattcca attgggtcca
     1261 agccattagt aggttcgtct aatataagta gtttaggtga atttattaaa gagatagcta
     1321 tacctaaccg ttgcttcatt ccaagagaaa attgttttac tggtctcttg tcaatatttc
     1381 ctagaccaac tttatttaat aatggaagta tagtgctttc tgaaacacca agcattgttg
     1441 taactacctt catattatcg taagcactca aatttttata aagtggtggt tcttcaataa
     1501 tactcccgat ttttcgcaga tcccgacgtg accattctct accttcaaaa ataatagaac
     1561 cacttgtctt actaactaag cctgtcaaaa ttttcataat agttgatttt ccagcaccat
     1621 ttggaccgat taaagcatac acttttccct taggaatatt catattgaca ttattcaata
     1681 tggttctctt accataagat ttttttagat tttgtatttt caacatatta gttactccca
     1741 ttctatatat tgctgagcgt ttagtgtata gtaagcaaaa caatacactt tctcttcaaa
     1801 ctctctatca atcccgttta atcgattcat cgatagttgt aaaatgaaac ttaccatcac
     1861 tatatcttat ataaatatcc tccaatcgca gttcattctc tgaatcccat gatgtggtaa
     1921 aaaatgaagt attataagac tcatcactat ataactttga taattcaccc aatccaacat
     1981 tttcacgcag tgtcaattca tactttaaaa aatcttggaa caatgcggat attctcttgt
     2041 agtatgactt tttctgtatt gaacaaagat taataccatt tatatatata tattgccttc
     2101 ataattatcg taaagaccgc aggctaattt gaaaatcgta ctttttccag aaccatttcc
     2161 accaacaatt gctaacctct ctcctgcttt aattgaaaaa cttatatcgt ttattacatt
     2221 atccttacca ttatatgaaa aagaaaccct ttcaaattca actgactgaa ttgtatcaac
     2281 cgtactttcg attatagggt tatgtactaa ctcatcatgc gtaaaatcat acaataactc
     2341 catgtacaat gaaccattta gggagaaacc agcctctttt acgagatgaa ttgtttttat
     2401 tagattcttt agctgagctt taatcatgta taacttcctt atctactaat aaaggagcaa
     2461 actaaaatca gtctactccc ctaaatttat aaatatataa aattatttga aattataatg
     2521 tttatgataa tgataacttt attatttaac agttgttgta aagcaaacta atttccaaca
     2581 agaaccaggg gtacataggt aacggctacc aacataaggt gtagcagtgt cttttttatt
     2641 tgttttcaaa tcgagatcaa agtctttaat tgtgttattc attttctagt tcctctctta
     2701 cgtttttgca tccgatatat ttacatgatt attatgacac cccaagttca gaatttgttc
     2761 agaaaaaaag tattttagcc aaaaatttac gattttttgc ctgaaatact ccagtttcaa
     2821 tcaaatctat taaattttct tttttatcga gattatggcg ctagcacctc ctctagctgg
     2881 attattcaat tgaagattcc caccgtgttt gatagcaacg cctttaacaa atgccaaacc
     2941 gattccataa tgtttgttac ctctgctata atcttccgtg taaaataatt tatctccctt
     3001 tttcagtgta ctatcactga aacgctcacc attattccat atttcaaaat gaatttgctc
     3061 tcctgactca gacagtataa cttcgatttt tttatctaat acgggcataa atcttattgc
     3121 attaactaaa aggttagaaa gagctcttat cagattttcc tcatctccat aaaaagaagt
     3181 gataataagt ctattacaaa tagaaaattc aatattattg atattcaata agtcatcgac
     3241 ttcaaaatgt aactcactta atagctcctc aactaaaatt agtttcactg atctatcctc
     3301 tgaaagcatg cgtgtataag atattaaaga attgaaatag ccttcaaaaa cagaaatact
     3361 attgttcata gatacaatat aaccttcctg atttttattt aaagtagtca attctaataa
     3421 ctcaagattt cctttcaaaa ccgttaaagg tgtttttata tcatgcgaaa gtgctgcaat
     3481 ttgaaaggat agatcttgct tttccaatat ttctcgctca atcaaacttt tcaaattat
//
LOCUS       DATTYN010000058         3183 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.58, whole genome shotgun sequence.
ACCESSION   DATTYN010000058 DATTYN010000000
VERSION     DATTYN010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3183
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.58"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(<1..173)
                     /locus_tag="VB649_001807"
     CDS             complement(<1..173)
                     /locus_tag="VB649_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP1670727.1"
                     /translation="MPRKTFDKAFKLSAVKLILEEEQPVKMVSSTLKIHPNSLYRWIQ
                     EYEKYGESAFPGHG"
     gene            complement(251..1561)
                     /locus_tag="VB649_001808"
     CDS             complement(251..1561)
                     /locus_tag="VB649_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEP1670728.1"
                     /translation="MIHLIIISAIALAIGIGYRTKINIGLLAIAFSYLIATTLIGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLIAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSGSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYIRYSKGRTNSSLTIDQPPVLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRQTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWAIIIMLCGMSLLMSLAVKSGLVTLIGHLITTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPTLFPIIATISAQSPHIDIRLLTTATIIGALSTNISPFSSAGSL
                     IQLSLPHIEERSLAFKKQILLGVPISLSLALLTIWILMLLASLS"
     gene            1785..2657
                     /locus_tag="VB649_001809"
     CDS             1785..2657
                     /locus_tag="VB649_001809"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEP1670729.1"
                     /translation="MSIISIDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGV
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            complement(2957..>3183)
                     /locus_tag="VB649_001810"
     CDS             complement(2957..>3183)
                     /locus_tag="VB649_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP1670730.1"
                     /translation="PSMSRKGNSPDNGMMDSFFGILKSEMFYGLEKSYKTLDKLEEAI
                     TDYIFYYNNKRIKAKLKGLSPVQYRTKSFQ"
BASE COUNT          957 a          556 c          732 g          938 t
ORIGIN      
        1 ccatgtcctg ggaacgcact ttctccatat ttttcatatt cttgaatcca tcgataaaga
       61 ctattgggat gaatttttaa agttgaacta accattttta caggctgctc ttcctcaagg
      121 atgagtttta cagcagagag tttgaaggct ttatcaaagg tttttcttgg cataatgact
      181 tttcctcgtt tccacttaat tttgtgtcta ctttattata ccaagtccag ccttaagtta
      241 gacaataaat ctaacttaag gaagctagca gcatgagaat ccagatggtc aagagtgcca
      301 aacttaagct gatgggcaca cccagaagaa tttgtttttt gaaagcaaga ctgcgttcct
      361 ctatatgggg aagggagagt tgaatgagag aaccagctga tgaaaaagga gagatattag
      421 tagatagagc gccaataata gtggctgttg tgagtaagcg aatatcaatg tgaggacttt
      481 gagcactgat ggtagcaatg atgggaaaga gagttggggc tacaacggat agggtggaac
      541 taaagagtga catcactccg gctatcacac aaaagaacag aggtaaccag aaatgaggaa
      601 tggttgttgt tatgaggtgc cctatcagtg taactaaacc tgacttgacc gctagagaca
      661 ttagtaagct catgccgcag agcatgataa ttatagccca gggaacctta gccaaaatgg
      721 cttcttgctt ccctaatttg agccttaagg cgaggcagac catgagtatt gagacaaagc
      781 caatatcaaa tgtttgtcga taagtagcta tccatgcgat gtttgggaaa atgagatgca
      841 acaagggaaa aagccaaacc aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt
      901 ggaccttgct gaggactggt ggttggtcaa tagtcaagga tgagtttgtt cttcccttac
      961 tgtagcggat gtaacaagat aataaaagca agacgatgag tgggtagata atgctgacga
     1021 taaagatatg attgccaagt gaaaaagctt gctcttccca tcccatttgc ttaaacaggc
     1081 cttgaaagac aatgcctgag ccactggtta tcaaattagc ccctcctgaa gctccccaat
     1141 tgacggcttg agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta
     1201 gaggacagca aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg
     1261 ctatcaggta taaaatcatg tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt
     1321 gttgagccaa aacatcaaga gtgccgttag ttgttgcaac gttataaaag agagagacgc
     1381 taaaaatggt aaaaaagagt gaggttggcc aaaaatgaag aagttctttg gggcttaatc
     1441 ctatgagagt ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt
     1501 tggtgcggta accaattcca atggctagag caatggcgct aattattatt aaatgaatca
     1561 ttgaattgtc ctttagttag aatatgaaaa taggttggca attttggcgc tcaaaagacc
     1621 acctgtttcc tattggtact tgactattat acacaaaaaa attacaattg tcttgacact
     1681 tgttgggatt taaaatgagg tattcaggtt tgtgatttcc tacggaagtt aatagcaatt
     1741 gcctctagtg cttacaagtg atattaaaaa tagaggactt agtgatgtca atcatttcaa
     1801 ttgatttaac cccttttcaa atagatgata cattgaaagc agccttgcga gaagatgttc
     1861 attccgaaga ttacagtacc aatgccattt ttgatcatca tggccaagcc aaggtgtcgc
     1921 tttttgccaa ggaagctggt gttttagcgg ggctaaccgt ttttcaaagg gtttttaccc
     1981 tatttgatgc cgaggtgacc ttccagaatc ctcatcaatt taaggatggg gatcgtttga
     2041 ctagtggcga tttggtttta gaaatcatag gctcggtgag aagcctctta acatgtgaac
     2101 gcgttgcctt gaatttttta caacatttat cagggattgc ttcgatgaca gctgcttatg
     2161 tagaagcctt aggcgatgat cgcattaagg tatttgatac tcgaaaaacc actcctaatt
     2221 tacgtctttt tgagaaatat gccgtgagag ttggcggtgg ctataatcat cgctttaatt
     2281 tatcagatgc tatcatgcta aaagacaatc acattgcggc agtaggtagt gttcaaaagg
     2341 cgattgctca agcgcgtgcc tatgcccctt ttgtgaaaat ggtcgaggtg gaagtggaaa
     2401 gccttgctgc tgccgaagaa gctgcggcgg cgggtgttga tattatcatg ttggataata
     2461 tgtcattgga acagattgaa caggccatta ctctaattgc aggacgttct cggattgaat
     2521 gttctggaaa tattgatatg accactatta gccgttttcg tggtttagcg attgattacg
     2581 tctccagtgg tagtttaacc catagtgcta agagtctcga tttttccatg aagggtttaa
     2641 cctaccttga tgtctaagtt gcaaaataaa ctaacttttt aaaggatgtc tttcctctag
     2701 aacgagtttt atgtcagata gtttaaacga ctcttcaaat actttccctg ttttcacctg
     2761 attcgtgtcc gcttattata ccaattccaa gcattcactt gaaaaaacga tagggagagg
     2821 ttagtgtttt tattgtaaaa gttccacgcc aaatccatga agaaaagttt gttttcagaa
     2881 atcacgattc atcataataa aatcaatcaa agtcgttaac taggagtgta ctgaccccaa
     2941 aaagttggac aaataattat tgaaaggatt tagttctgta ttggacagga ctaagtcctt
     3001 ttagttttgc tttgattcgt ttgttgttgt agtaaaaaat gtaatctgta atagcttctt
     3061 caagcttgtc aagggtttta taagactttt caagtccata gaacatctcc gatttgagaa
     3121 tgccaaagaa ggaatccatc atgccgttat ccgggctatt ccctttgcgg gacatggatg
     3181 gca
//
LOCUS       DATTYN010000059         2746 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.59, whole genome shotgun sequence.
ACCESSION   DATTYN010000059 DATTYN010000000
VERSION     DATTYN010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2746
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.59"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..641
                     /locus_tag="VB649_001811"
     CDS             <1..641
                     /locus_tag="VB649_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEP1670731.1"
                     /translation="LVGNYVHSYFESKKAHEEFKAQNGSEMISTRGATKGQLKKDYLV
                     AEQMIDALKSDSNFMAIYQGEKEAAITGFLGEIEFKSKIDCLNVERGYFVDIKTTKGQ
                     IDDTIWNGEERVRWFEAYGYILQMAAYKNMLEAKYNKPFEPIIYAVTKETPPDTRAIR
                     IQNVDAMQMELDSLAQSIKRLDDVKKGIEKPKPCGKCEYCRQNKLSVRVEIF"
     gene            651..818
                     /locus_tag="VB649_001812"
     CDS             651..818
                     /locus_tag="VB649_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670732.1"
                     /translation="MTKYYVSAKIANLDIGAEIEAENQHMAPIAFKETYDHLLRFGSH
                     KLRILGVEEVN"
     gene            918..1316
                     /locus_tag="VB649_001813"
     CDS             918..1316
                     /locus_tag="VB649_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670733.1"
                     /translation="MYYEFVLSNTKQKKEMLSSNDRLHFRKSASITKGLRQLAKLKSN
                     GLTKKHTKNNPCKVIVTVFTPTKRRFDPPNIYPTIKAILDGFTDAGVWDDDNHEIIKS
                     LTFRYGGLSNVKGKYRIAIEILEMETHDYY"
     gene            1303..1497
                     /locus_tag="VB649_001814"
     CDS             1303..1497
                     /locus_tag="VB649_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670734.1"
                     /translation="MTTTKKHVVRVYNKGIIATYMVYDKKLFKEHEFATKREAMQFIR
                     QLELSNDKRATEYYLREVVE"
     gene            1494..1907
                     /locus_tag="VB649_001815"
     CDS             1494..1907
                     /locus_tag="VB649_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670735.1"
                     /translation="MIPNFRGFNKKTKKMYSIDGFKSSERKIYRCSLADDEFRSGRLE
                     TFHFVEDNLDDYILRQSTGLFDKNGVEIFEGDVVKLQYTITSDLEFFKVNQFRGGSWR
                     IDNRRRGSDLWLRNEDCEVIGNIYQNSDLIESVEE"
     gene            1904..2188
                     /locus_tag="VB649_001816"
     CDS             1904..2188
                     /locus_tag="VB649_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670736.1"
                     /translation="MTTDELLQNLRDDLNKIINVLKNDWKALLFLAIAIFGMMVIVSY
                     FSYRDARQYYESQITGLRTQLSRTQKQLKRASEQNQRQTKRIAEMTGNGG"
     gene            2192..2674
                     /locus_tag="VB649_001817"
     CDS             2192..2674
                     /locus_tag="VB649_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEP1670737.1"
                     /translation="MTDIKILDACCGSRLFWFDKNEPHTTFMDVRQEKFEMHGKKINV
                     NPDVIGDFRDMPFESNSFNLVVFDPPHLKYVGQNSIMKAQYGQLDKENWKEDISKGFE
                     ECMRVLKVGGTLVFKWSDCQVNVREVLSAIPFKPLFGQQRGTTHWMTFVKFELTGNGG
                     "
BASE COUNT         1007 a          431 c          590 g          718 t
ORIGIN      
        1 tgctcgtcgg gaactatgtc cactcttact ttgagagtaa aaaagctcat gaagaattca
       61 aagcccaaaa cggctctgaa atgatttcga cccgaggagc aacaaaaggc caattaaaaa
      121 aggattactt agttgctgaa cagatgattg acgctcttaa aagtgatagt aactttatgg
      181 ctatttatca aggagagaag gaagcagcca tcacaggatt tcttggcgag attgaattca
      241 agagtaaaat cgactgcttg aatgttgaac gtggctattt tgtagacatc aaaacaacaa
      301 aagggcagat tgacgacaca atctggaatg gagaagagcg tgtcagatgg tttgaagctt
      361 atggatatat cttgcagatg gctgcctaca aaaacatgct agaagctaag tataacaaac
      421 cgtttgagcc gattatctac gcagttacta aagagacacc accagataca agagccatca
      481 gaatccaaaa tgtagatgct atgcagatgg agttagatag cctagcacaa agcattaagc
      541 gattagatga cgttaaaaaa ggcatagaaa aacctaaacc ttgcggaaaa tgcgaatatt
      601 gcaggcaaaa taaattgtct gtaagagtag agatttttta ggagataaaa atgactaaat
      661 actatgtatc agctaagatt gcaaatctag acataggtgc agaaatcgaa gcagaaaatc
      721 agcacatggc tccgatagca tttaaagaaa cgtacgacca tttacttaga ttcggaagcc
      781 ataagctgag aatattaggc gtcgaagaag ttaattaaca acctattaac aggattgatg
      841 atatgaagaa ttgctacact cgtccttgcc aatgctcaca cacaatttta gggcgagtgt
      901 ggattttaag agaatatatg tattatgaat ttgttttatc aaacacaaaa cagaaaaagg
      961 aaatgttatc aagcaatgat cgcttgcatt ttagaaaatc agctagtatc acaaaaggat
     1021 tacgacaatt agctaaacta aaatcaaacg gactgactaa aaaacacact aaaaacaatc
     1081 cttgcaaagt tatcgtgaca gtgtttacgc cgacaaaacg acgatttgac cctccaaata
     1141 tttatccgac aataaaagca attttggacg gctttacgga cgctggtgtt tgggatgatg
     1201 acaatcacga aatcataaaa tcactcacgt ttaggtatgg aggattaagc aacgtaaaag
     1261 ggaaataccg cattgcgatt gaaattttag aaatggagac acatgactac tactaaaaaa
     1321 cacgttgtaa gagtttacaa caaaggtatt atagcgactt acatggttta tgacaaaaaa
     1381 ctgtttaagg agcacgagtt cgcaacaaaa agagaagcaa tgcagtttat tagacagcta
     1441 gagttatcta atgataagcg agcgacagaa tattatttga gagaggtagt ggaatgatac
     1501 caaattttag agggtttaac aaaaaaacta aaaaaatgta tagcattgat ggctttaaat
     1561 caagtgaacg caaaatatac agatgcagct tagcagatga tgagtttcgc tctggtcgct
     1621 tagagacgtt tcattttgtc gaggataacc ttgatgatta tattctcagg caatcaacag
     1681 gactgtttga taaaaacggc gtggagattt ttgagggaga cgtcgtgaaa ttacaatata
     1741 caattactag tgatttagaa ttttttaaag tgaatcaatt cagaggtggt tcttggcgca
     1801 ttgacaatag acgacgcgga tcagatttgt ggttaagaaa cgaggactgc gaagttatcg
     1861 ggaatatata tcagaacagc gacctgatag aaagtgtgga agaatgacaa cagatgaatt
     1921 attgcaaaat ttgcgtgatg acttgaataa aataattaat gtcctaaaaa acgattggaa
     1981 agcactattg tttcttgcaa tcgcaatatt tgggatgatg gtaatcgtgt cgtattttag
     2041 ctatcgcgac gcacgacaat attacgagtc gcaaatcaca ggactacgta cacagctaag
     2101 caggacacaa aagcagctta aacgtgctag cgagcaaaat cagagacaga caaagcggat
     2161 tgcggaaatg acaggtaatg gaggatagag aatgacagac atcaagattt tagatgcttg
     2221 ttgtggaagt cgcctatttt ggtttgataa aaacgaacct cacacaactt ttatggacgt
     2281 cagacaagaa aaatttgaga tgcacggcaa aaaaatcaat gtcaaccctg atgtaattgg
     2341 tgattttcgt gacatgcctt ttgaaagtaa tagctttaac cttgttgtct tcgatccacc
     2401 acacttaaaa tatgttggac aaaactcaat tatgaaagcc cagtatggtc aacttgataa
     2461 agaaaactgg aaagaagata tttcaaaagg tttcgaagag tgtatgagag ttctaaaagt
     2521 aggaggaact ttagttttta aatggtctga ttgtcaggtt aatgtaagag aagttttgtc
     2581 agcaattcca tttaaaccgc tttttggcca gcaaagaggc actacacatt ggatgacatt
     2641 tgttaaattt gagcttactg gaaatggggg atagtgatgt gaaatgcgaa ttgtataatg
     2701 atcattttga gaacgctaaa cgttacaaca taccaagagc gcaatt
//
LOCUS       DATTYN010000060         2611 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.60, whole genome shotgun sequence.
ACCESSION   DATTYN010000060 DATTYN010000000
VERSION     DATTYN010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2611
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.60"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            12..683
                     /gene="sdaAB"
                     /locus_tag="VB649_001818"
     CDS             12..683
                     /gene="sdaAB"
                     /locus_tag="VB649_001818"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEP1670738.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGDIPD
                     EVTFHLYNSFAKTYRGHGTDKALVAGIMGMDTDNPDIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKTLSVTGVSIGGGNIQVTELNGFSVSLSMNTPTIVTVHKDI
                     PGMIAKVTDILSSNNINIATMNVTRESAGEKATMIIEVDSRECQEAANQIAKIPHIYN
                     VNFFD"
     gene            695..1567
                     /gene="sdaAA"
                     /locus_tag="VB649_001819"
     CDS             695..1567
                     /gene="sdaAA"
                     /locus_tag="VB649_001819"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEP1670739.1"
                     /translation="MFYTIEELIKQADQQFNGNIAELMIATEVEMSGRNREDIIKIMS
                     RNLQVMKAAVTEGLTSTKSISGLTGGDAVKMDDYIKKGNSLSDTTILNAVRNAIAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLATAIEKLDLSEKKQLEFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSAAAMSAAALVKAAGGTSHQASQAIAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGASFALVAADMALADIESQIPVDEVIDAMYQVGSAMPTAFRETAEGGLAA
                     TPTGRRYSVEIFGE"
     gene            complement(1981..2595)
                     /locus_tag="VB649_001820"
     CDS             complement(1981..2595)
                     /locus_tag="VB649_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HEP1670740.1"
                     /translation="MFKKENLKQRYFNFGLVALALTILAIIFAFSSKNADTKSYAKKS
                     ESKMVTIDKAPKNNHAITKEECKEKAKSIASEPIPTVENSVAPTVTEEAPVVQQEVTQ
                     TVQQVSSVAYNPNNVVLSNGNTAGIVGSQAAAQMAAATGVPQSTWEHIIARESNGNPN
                     AANASGASGLFQTMPGWGSTATVEDQVNAALKAYSAQGLSAWGY"
BASE COUNT          810 a          489 c          493 g          819 t
ORIGIN      
        1 cggagttgcc tatgaataca caaaaatttc aatcagtttt tgacatcatt gggccagtaa
       61 tgattggtcc atcaagtagt cacacagctg gtgccgtcag aattggtaag gtagtccatt
      121 ccatctttgg agatattcct gatgaagtga cgtttcacct ttataattca tttgctaaaa
      181 cctacagagg acatggtact gataaggctc ttgttgcagg aattatgggt atggatactg
      241 ataatcctga tattaaaaat tctctagaaa ttgctcatca aaaagggata aaaatctatt
      301 gggatatctt aaaagatagt aatgctcccc atcccaatac tgttaaaatc agtgtcaaaa
      361 aagctgacaa aacacttagt gttactggtg tttcaattgg aggaggaaac attcaagtaa
      421 cagaactaaa tggtttttct gtctcgttat ccatgaatac tcctactata gttactgtac
      481 acaaagatat tcccggaatg atcgcaaagg taactgatat cctatcttcc aataatatta
      541 atatcgccac aatgaatgtt acacgtgaat ctgctggtga aaaagctact atgattatag
      601 aagtcgattc tagagagtgc caagaagcag ccaaccaaat tgcaaaaatt cctcatattt
      661 ataatgtcaa cttctttgac tagaaaggaa agctatgttt tatactattg aagaacttat
      721 caaacaagct gaccaacaat ttaatggaaa tattgctgaa ctcatgattg ccacggaagt
      781 ggagatgtct ggaagaaatc gagaagatat tatcaaaatc atgtcacgca atttacaagt
      841 tatgaaagca gctgtaacag aaggactaac ctcaaccaaa tctatcagtg gtttgacagg
      901 gggcgatgcg gtcaaaatgg atgactacat taaaaaaggg aacagccttt ctgatactac
      961 tattcttaat gctgttagaa atgctatagc tgtaaacgaa ttaaatgcta aaatgggact
     1021 tgtctgtgca acacccactg caggaagtgc aggatgctta ccagcagtgc tcgcaacagc
     1081 tattgaaaaa cttgacttat cagaaaaaaa acaattagag tttttattta ctgcaggagc
     1141 ttttggtctt gttattggaa ataacgcctc tatttctggt gcagaaggtg gatgccaagc
     1201 agaagttggt tctgcagctg ctatgagtgc agctgctctt gttaaagcag ctggtggaac
     1261 atctcatcaa gctagtcaag ctattgcgtt tgttatcaaa aatttattag gacttgtctg
     1321 tgatcctgtt gccggcctag tagaagtgcc ttgtgtcaaa cgcaatgccc taggagcaag
     1381 tttcgccctt gtcgcagctg atatggcttt agctgatatt gaatctcaaa ttcctgttga
     1441 cgaagttatt gatgctatgt atcaagtcgg ctctgccatg ccaactgctt tccgtgaaac
     1501 agcagaaggt ggtttagccg ctactccaac tggacgacgt tacagcgtag aaatatttgg
     1561 cgaataaata gatggttaga aaaattctta gaaatatttg aaagcgtttt atttttctgc
     1621 tatatattca ctaaaatgac taatagatag ctatcaagct atgttgtttt cccttagaaa
     1681 caactcctag taaattgtta aaactcaaaa gtgtagtagt gtaaaatact gaaaattgct
     1741 aatgacctta taaacattta agagtttttt tcctgcttct tatcagtata actgccttaa
     1801 atatcagagg cacttaagtg ctggtcagtt ttcctaaata atacgagcta tattccctga
     1861 taaggcaatg ttttgttttg agactaattc atcactacaa atcataaaga caattaaata
     1921 ccaaaaacct attgttagta aatactaaca ataggtttta tttcttccag ccatgtttat
     1981 ttagtaaccc caagctgata aaccttgtgc actataggct ttcaaggctg cattgacttg
     2041 atcttcaacc gttgctgtag aaccccaacc tggcattgtc tggaacaacc ctgatgcccc
     2101 agaagcatta gctgcgttag gatttccatt agattcacgc gcaattatat gttcccaagt
     2161 tgattgtgga acacctgttg ctgctgccat ctgtgccgcc gcttgacttc ctacaatacc
     2221 agcagtattt ccattggaaa gtaccacatt gtttggatta taggctactg aagatacctg
     2281 ctgaacagtt tgagtcactt cttgctgaac aaccggtgct tcctctgtta ctgtcggagc
     2341 tacagagttt tctactgtgg gaataggctc cgaagcaatg ctctttgctt tttctttgca
     2401 ttcttcttta gtaatagcat gattattttt tggagccttg tcgattgtta ccattttact
     2461 ttctgacttc ttagcataag acttagtatc agcattttta cttgagaagg caaaaatgat
     2521 ggctaatatt gttagagcta acgctactaa tccaaaatta aaataacgtt gttttaaatt
     2581 ttctttctta aacattcaat aatacctcac t
//
LOCUS       DATTYN010000061         2520 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.61, whole genome shotgun sequence.
ACCESSION   DATTYN010000061 DATTYN010000000
VERSION     DATTYN010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2520
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.61"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..462
                     /locus_tag="VB649_001821"
     CDS             <1..462
                     /locus_tag="VB649_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEP1670741.1"
                     /translation="KKYIEQKYKNISFSIDYHYYLTTTGSCIDFGEEGAVGRGNKTHG
                     IISSFRPNTMEAPAGKNCTYFVGKVWGFLSDTIAKEIYEVFNTPCQIIMQLNIGSKLY
                     RPTHLFIQTEESVDQERVLEIVNRHLNNGKQNTNLILSTQHFIPKTNVYDG"
     gene            446..1414
                     /locus_tag="VB649_001822"
     CDS             446..1414
                     /locus_tag="VB649_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HEP1670742.1"
                     /translation="MFMMDKTVLYFGLVEISFDVPDFIFQKIKEQNNKIRYYSKSINI
                     LGSVKFINSNQQFIEYDGNGNILVYGRLKYFKEGISLYYIGEYLAECLLIEHSDTLLI
                     HAAAVYNPLSGHSILLLGDKGAGKTTVAIRLCIEHGYHLIGNDQVIFGSNSGILLTYA
                     GTSFFKIRRTAVLSDNLLFKLFSKFFNRSLQFNKASWDDKISIFPKELGIRTCNFSTE
                     ISKIYYIKTDKKEKQIYHSIWNDSLASLYLNELLGRHISGQVACFQSDNGKYFSTMPL
                     INYEKNNRVREQIVKGIFAKQKLFKITAATPAKIAEAIIENVKKNS"
     gene            1469..2458
                     /locus_tag="VB649_001823"
     CDS             1469..2458
                     /locus_tag="VB649_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEP1670743.1"
                     /translation="MFVIGIPTLNEADNISRLVKQIDEYAVNLGKEIIIINSDSKSTD
                     GTPQIFLETKTYNTKVSIVSEAKGKGYNVRNIFEYAINHVPNFSGLILIDGDVVSMKK
                     MWLEKMFIAIESGNDLIIPNYARKSFEGNATNHFIYPMLVKFFKRDMPYQCISGDFGF
                     SRGLIKDLTLKCNWHKYTLGYGIDIFLTLTAILKSYKIKEIDLQSKIHKKSFEKIEKI
                     FLEVSQSFFKTINDNSLNQDKLRLNINFESHSRQFIKSSDILSSNDIENLKLRALFLL
                     QEEKQYPHGLSEVEWDGILSNTINNIYRYSSEEHSLYLLPLYLLRVYNYLKYN"
BASE COUNT          943 a          288 c          435 g          854 t
ORIGIN      
        1 aagaaatata ttgaacaaaa gtataaaaac ataagctttt ctattgatta ccattattat
       61 ttaactacta caggttcttg tattgatttc ggagaagaag gtgcagttgg tcgaggtaat
      121 aaaactcatg gtatcatatc aagttttagg ccaaatacta tggaagcacc agctggaaaa
      181 aattgtactt attttgtagg aaaggtttgg ggatttttgt ctgatactat tgccaaagaa
      241 atttatgaag tattcaatac tccctgtcaa atcattatgc aattaaatat tggatcaaaa
      301 ttgtatagac caacccattt atttattcag acagaagaaa gtgttgatca agaaagagta
      361 ttagaaattg ttaacaggca tttaaataat ggtaaacaaa atactaattt aatcttgtca
      421 actcaacatt ttattcctaa aaccaatgtt tatgatggat aaaactgttt tatattttgg
      481 gttggttgaa atttcttttg atgtacctga ctttatattt caaaaaataa aagagcagaa
      541 taataaaatt agatattata gcaaatcaat aaatatatta ggtagtgtaa aatttattaa
      601 cagcaatcag caatttatag aatatgatgg caatggaaat attttagttt atggaagatt
      661 aaagtatttt aaagaaggaa tttcattata ctacattgga gagtacttag ctgaatgtct
      721 cttgattgaa catagtgaca ccttattaat tcatgcagca gcagtttata atcctttatc
      781 tggccattca attttactat taggagataa aggtgctgga aaaactacgg ttgcaataag
      841 gctttgtata gaacatgggt atcaccttat tggtaatgac caagtaatat ttggttcgaa
      901 ctctggaata ctactaactt atgcagggac atctttcttt aaaataagaa ggacagctgt
      961 tttgtcggac aatttactgt ttaaattatt tagcaaattt tttaatcgtt cattacaatt
     1021 taataaggca agttgggatg ataaaatttc aattttccca aaggagttgg gaatacgaac
     1081 ttgtaatttt tctactgaaa tctcaaaaat ttattatata aagacagaca agaaagaaaa
     1141 gcaaatttat cattcaattt ggaatgatag tttagcaagt ttatatctaa atgagctatt
     1201 gggaaggcat atttctggac aggttgcatg ttttcaatca gataatggaa aatatttttc
     1261 tacaatgcct ttgataaatt atgaaaaaaa taatcgggta cgagaacaga tagtgaaggg
     1321 tattttcgct aaacaaaaat tatttaaaat tacagcagct acgccagcta agattgcaga
     1381 agcgattata gaaaatgtta agaaaaactc atagtgtgtg tgaatttggg gattaatatg
     1441 aagtattgaa aaaggagtaa gagtaattat gtttgtgata ggcattccaa ctttaaatga
     1501 ggcagataat atcagtagat tagttaaaca aattgatgag tatgctgtaa atttagggaa
     1561 agaaattatt attattaatt cggatagtaa aagtacagat ggaactccgc agattttttt
     1621 agaaaccaaa acttataaca ccaaagtttc gatagtatca gaagctaaag gaaaaggtta
     1681 taatgtgaga aatattttcg aatatgcaat aaatcatgtg ccgaatttct ccggtttaat
     1741 tttgattgat ggagacgttg tctcaatgaa aaaaatgtgg ttagaaaaga tgtttatagc
     1801 aattgaatct ggaaatgatc ttataatccc aaattatgct agaaaatctt ttgaaggaaa
     1861 tgcgacaaac cattttattt atcccatgtt agtgaaattt ttcaaacgtg atatgcctta
     1921 tcaatgcatc tctggtgatt ttggattttc aagaggattg ataaaagatt taactttgaa
     1981 gtgtaattgg cacaaatata cattaggtta cgggatagat atttttttaa ccttaacagc
     2041 tatattaaag tcatacaaaa ttaaggaaat cgatttacaa tcaaagattc ataaaaaaag
     2101 ctttgagaaa attgaaaaaa tttttttaga agtttcacaa agtttcttca aaactattaa
     2161 tgataattct ttgaatcaag ataagttacg tttaaatata aattttgaaa gtcattcaag
     2221 acagtttatt aagtccagtg atatcctatc cagcaatgat atcgagaatt taaagttaag
     2281 agcgttgttt ttattacagg aagaaaaaca gtatccacat gggctgtcag aggtagaatg
     2341 ggacggaatt ttgtctaata caattaacaa tatttataga tatagtagtg aggaacattc
     2401 gttatattta ttaccacttt atttattgag agtatacaat tatctaaagt acaactaagt
     2461 tttcaatttt tattaatctt gagaagaagt gtgattggtg gaatatattt caatatgttt
//
LOCUS       DATTYN010000062         2513 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.62, whole genome shotgun sequence.
ACCESSION   DATTYN010000062 DATTYN010000000
VERSION     DATTYN010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2513
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.62"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            202..936
                     /locus_tag="VB649_001824"
     CDS             202..936
                     /locus_tag="VB649_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HEP1670744.1"
                     /translation="MNLSIFGLKNIPYLKEGDSIEKLIEESIKTSGFFIEDNDVLCIA
                     SKVVSIAEGQVMSLNEIQVSDVAKEIHRNIPRKDPRIIEIMLNLVNRDLSRLDIKKNY
                     IGCRLENGLKLTSGGIDRKSVDEVFLLPNNPDASAKRISEYLKKSLGKNVAVVITDSD
                     GREDKRGATQVAIGIYGIHPLRKTEVIDSQGETIKFQEETLCDMIAACAGLVMGQRGT
                     GIPAVLIKGLDYKWSENTSIKEALNE"
     gene            929..1915
                     /locus_tag="VB649_001825"
     CDS             929..1915
                     /locus_tag="VB649_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HEP1670745.1"
                     /translation="MSRNQDCKNILIIGFGKIGKIKAYKWLSRGYEVYVKDLKFSSMK
                     YLNTNSDVLDDLSRQYFTIEICTPTNHHLTLLKTVITRYVYSYISIEKPLCNRLEDLE
                     EMKSLVESHPHLAKKIFASEQYFFSKILEKLLQVDCFSLDKIKEITVNFSKDRIEDNE
                     NGRFLDKEILGYGIEIPHIIAVISYLGISLEEFKKGIFVNAIYIKDLEKHDYSIEILS
                     CINQTVIKIISNLGSFAIREGKIEGGDAKTVRRVTIDDKTILFDPHPKLERYKSELVT
                     GTNTFQIHDDMMDTYISLLEGNAIPEDCYINNAIEITKLLINLYSECEKIYL"
     gene            1925..>2513
                     /locus_tag="VB649_001826"
     CDS             1925..>2513
                     /locus_tag="VB649_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="HEP1670746.1"
                     /translation="MDLKITNGFYDPSHLSYEVVERKGLGHPDTLADGIAEQIEIDYS
                     LYCLDKFGVIPHHNFDKIIIRGGHSVQDFGGSDFIEPIKIIFLGRASKKCFNSSIPLF
                     KIQKKAATKYLNRILPNLDVENYVEFETLTSDFTTKTNWFSPEAIEDLPEYLDVPKAN
                     DTATMISYWPLTISEELALMIEGYFYKLDKNELPTP"
BASE COUNT          940 a          307 c          484 g          782 t
ORIGIN      
        1 atgttaacaa tgatttagga atacattatg tagaactagg taaaggaatt atcgattata
       61 aaacaatcat tcatgaaatc catgaacatt ttatagactt aatttttagt ttagaagtac
      121 atgaaaaaga aatagacaaa aaggcagaag tagtgaggaa gtcttatctg acactaaatg
      181 agtatattaa tggaggctaa aatgaatttg agtatatttg gtttaaagaa tattccttat
      241 ttgaaagaag gggatagtat agaaaagctt attgaagaaa gcattaaaac ttcaggattt
      301 tttatcgaag acaatgatgt gctttgcata gcttctaaag ttgtatctat cgcagaaggc
      361 caggtgatgt ctttaaacga gatacaagtg agtgatgtag caaaagaaat ccacaggaat
      421 attcctcgta aagatcctag aataattgaa attatgctaa atttagtcaa tagagatctg
      481 tcacgtttag atatcaaaaa aaattacatt ggttgtcgct tggaaaatgg tttaaagttg
      541 acaagtggtg gaatcgatag aaaatcagta gatgaagtat ttcttttacc taataatccg
      601 gatgcttctg caaaaagaat ttcggaatat cttaaaaaat cacttggaaa aaatgttgca
      661 gttgttataa cagatagtga tggtagagag gataaaagag gtgctactca agtagcaatt
      721 ggtatttatg gtattcatcc tttgagaaaa acagaagtaa tagattcaca aggagagaca
      781 ataaaattcc aagaagagac tttgtgtgat atgattgcag cttgtgctgg cttagtaatg
      841 gggcaacgtg gaactggaat tccagctgtc ctcattaagg gcttggatta taaatggtct
      901 gaaaatacta gtattaagga agcgttaaat gagtagaaat caggactgta agaatattct
      961 aatcattggt tttggaaaaa ttgggaaaat taaagcgtac aagtggctat cacgcggata
     1021 tgaggtatat gtcaaagatt tgaaattctc cagcatgaaa taccttaata caaatagtga
     1081 tgtgttggat gatttatcac gacaatattt tactattgag atttgtactc cgacaaatca
     1141 ccaccttacg ctattgaaaa ccgttataac aaggtatgtc tattcttata ttagcattga
     1201 aaaaccactg tgtaacaggt tagaagattt agaagaaatg aagtcgctag tagaaagtca
     1261 cccacatcta gcaaaaaaaa tttttgccag tgaacaatac ttcttttcga aaattttgga
     1321 aaaactgtta caagtagatt gtttctctct agataaaatc aaggaaataa cagttaattt
     1381 ttctaaagat aggattgagg ataacgagaa tgggagattt ttagataaag agatattggg
     1441 ctatggaata gagattcctc atatcattgc tgtcatttct tatttaggaa tttcattaga
     1501 agaattcaaa aaaggaatct ttgtgaatgc tatttatata aaagacttag agaaacacga
     1561 ttattcaata gaaatattat cttgtattaa tcaaacagtc attaaaatta ttagtaattt
     1621 gggaagtttt gcaataagag agggtaagat tgaaggaggt gatgctaaaa cagtaagaag
     1681 agttaccatt gatgacaaaa caatactatt tgatccacat cctaaactcg agaggtataa
     1741 gagtgaattg gtgactggga caaatacgtt tcaaatacac gatgatatga tggacacgta
     1801 tatcagtttg ttagaaggaa atgctattcc tgaagattgc tatatcaata atgcaattga
     1861 gataacaaaa ttattaatta acttatattc agaatgtgaa aaaatttatt tatgaggtgt
     1921 aactatggat ttaaaaatta caaacggctt ttatgaccca agtcatttat catacgaagt
     1981 agtagaacgc aaaggcttag gtcaccctga taccttagca gatggaattg ctgagcaaat
     2041 tgaaattgat tactcacttt attgtttgga caagtttggt gttattccac atcataattt
     2101 tgataagatt attatccgag gggggcattc agttcaggat tttggtggaa gtgactttat
     2161 tgaaccaatt aaaattattt ttctaggtag ggcgagcaaa aaatgtttta atagttcaat
     2221 tccacttttt aaaattcaga aaaaggctgc aactaaatat ttaaatagaa ttttacctaa
     2281 tttagatgtt gaaaattatg tagaatttga gacattgacc tcagatttta ctacaaaaac
     2341 taattggttc tcgcctgaag caatagaaga tttacctgag tatctagatg taccaaaggc
     2401 aaatgataca gctacaatga taagttattg gccattaaca atttctgaag aattagcatt
     2461 aatgattgaa gggtattttt ataaattaga taagaatgaa ttaccaacgc caa
//
LOCUS       DATTYN010000063         2433 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.63, whole genome shotgun sequence.
ACCESSION   DATTYN010000063 DATTYN010000000
VERSION     DATTYN010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2433
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.63"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(<1..1833)
                     /locus_tag="VB649_001827"
     CDS             complement(<1..1833)
                     /locus_tag="VB649_001827"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEP1670747.1"
                     /translation="MLLGKIRYLILFLVAIQSVLFALMAIFFTGVQYQESWQNYNRNS
                     STVTVYLQKLSDEQSQSVFRYFLEQNNLSIWTRRFETSEKGEGLSRIYVDILGNSEGF
                     SDVVNTSKVVISRTQFKTLLEHNDNSLTIGLDKGSSNMLYELPSLLFTTPVVIDRLDY
                     VFQKTNTINGTYYINGIKDRETEDDFLLGLSEITGITTDELTRESFGSSTDHGIWPIA
                     LAISIIVNSLIILVLLLICVLQSFKHFGILILLGWDRKALWNALFKKFLLFSIYITPV
                     SASVLWLLSGWFSFGLPALFPIFAGTSLSILVLCLILIIPSIIVYLVSPLAAIHKRLP
                     MKPLMVISLIFYVLVGVLLIAVSHSLDAPMNQFVDNIKVAREWKSVEDMYVISDFVEG
                     NDIGIYSGTTNSLERDMYSFYQSISDLPGVYIAQGEYLDNQYLNTVQGTYQNVPSRPF
                     WYLTYSYNYLSDFGVDLSEDELSEIKGGTRLYLIPETLSTAEIEVMKGYLQEIVTVKS
                     GDIETRFTKNPTFLFKTYQPSNSIFTWSTSIANGVTSKEPIIFVASPENLYFMETANL
                     FVSGYNGFLKFRDEKVMNQVKSILKNDFTNLSDNKLRFKTVKNYI"
     gene            complement(1855..2148)
                     /locus_tag="VB649_001828"
     CDS             complement(1855..2148)
                     /locus_tag="VB649_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670748.1"
                     /translation="MKNNIKKFISTSLIALTLAGAGGSIVSAATVYYNGTAVYWDYGR
                     TAGLWSYSNVQSGVYEHSSTANGAFSGWKKPGVEARASKFIGNATAQCYWNCR"
BASE COUNT          860 a          462 c          326 g          785 t
ORIGIN      
        1 aatataattt tttaccgttt taaaccttaa cttattgtct gacaaattag taaaatcatt
       61 ttttaaaatt gattttactt gattcattac tttttcatca cggaatttca aaaaaccatt
      121 atagccacta acaaataaat tagctgtttc cataaaatat aagttttcag gggaggctac
      181 aaaaattatt ggttctttgc tagtcactcc atttgcaata gacgttgacc aagtaaatat
      241 agaattcgag ggttgataag ttttaaataa aaatgtagga ttctttgtaa atctagtttc
      301 tatatcacct gatttgactg ttacaatttc ttgcaaatag cctttcataa cttcaatctc
      361 tgctgtactc agtgtctcag gtataagata gagcctagtg ccacccttta tttctgatag
      421 ttcatcttca cttaaatcaa cgccgaaatc tgataaataa ttatatgaat atgttaaata
      481 ccagaaaggt ctgctcggaa cattttgata agtcccctgt actgtattaa gatattgatt
      541 atctagatat tctccttgtg ctatataaac tccaggaaga tcagaaatac tttgataaaa
      601 actatacata tctctctcta aggaatttgt agtaccagaa taaatcccaa tgtcatttcc
      661 ctcaacaaag tccgagataa catacatatc ctctacactc ttccattctc tagctacctt
      721 tatattatca acaaactgat tcattggtgc atctaatgaa tgactaactg ctatcaataa
      781 aactcctacc aaaacataga atattaaact aataaccatt agaggtttca taggtaaacg
      841 tttatgaatg gcagctaagg gtgaaaccaa ataaactata atacttggta taataagaat
      901 taaacataat actagtattg acagacttgt acctgcaaaa attggaaata atgcaggtaa
      961 accaaagcta aaccaaccag acaaaagcca aagaactgat gcggacacag gagtaatata
     1021 gatagaaaat aatagaaatt tcttgaaaag agcattccat aatgctttcc tatcccaccc
     1081 taaaaggatc agtatcccga aatgcttgaa ggattgcaaa acacaaatca ataataaaac
     1141 aagaataatc aaggaattca ctatgatact aatagctaaa gcaatcggcc aaattccatg
     1201 gtcagtacta ctaccaaaac tttctctagt taattcatca gtagtaatac cagtgatttc
     1261 tgaaagaccc agtaaaaagt catcctctgt ttctctatct ttaatgccat tgatataata
     1321 ggtaccattg attgtatttg ttttttggaa aacataatct aaacgatcaa ttacaacagg
     1381 tgtagtaaat aatagactag gcaattcata aagcatatta cttgatcctt tatctagccc
     1441 tatcgttaag ctattatcat tatgttcaag tagagtttta aattgtgtac gagaaataac
     1501 tactttacta gtattcacaa catccgaaaa cccctctgaa ttccctagta tatctacata
     1561 aattctactt agcccttctc ccttttcact agtttcaaat cgtcttgtcc atattgataa
     1621 attattttgt tccaaaaaat atcgaaaaac actttgagat tgttcatctg acaatttttg
     1681 aagataaaca gtcactgtac tagaattacg attataattc tgccacgact cttgatactg
     1741 tactcctgta aaaaaaattg ccatcagagc aaataacaca ctctgaatgg caaccaaaaa
     1801 cagaattaag taccgaattt tacctaataa catgtttttg tatgtcatag gctgttaccg
     1861 acaattccaa tagcactgtg ccgtagcatt cccgataaat ttagatgcac gagcttcgac
     1921 acctggtttt ttccatcctg agaaagcccc gttagcagtt gacgagtgtt cgtatacacc
     1981 tgactgaaca tttgagtagc tccaaaggcc tgctgttcta ccgtaatccc aatatacagc
     2041 agttccatta tagtaaactg tagctgctga tacaattgaa ccccctgcac cagctagagt
     2101 tagagctatt aaagaagttg aaataaattt tttaatatta tttttcatga taaatattcc
     2161 atatgttcta caaaaagaaa attaacaaca agtaactcta caataaaatg ccaataacat
     2221 tcttaagcta aagcataagt gagcgtttta atatgaattt tctcatactt cttccctcct
     2281 taccaattat tttataatgt gtactactcc tggatctatc ccttgagact ttgaaatgaa
     2341 atttgctgaa ccctttacaa taaccagtaa tcccaagatt actcaagatt actaaagtaa
     2401 attttacgat tttttcattt ttgcaaaccc ttt
//
LOCUS       DATTYN010000064         2395 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.64, whole genome shotgun sequence.
ACCESSION   DATTYN010000064 DATTYN010000000
VERSION     DATTYN010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.64"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            237..1259
                     /locus_tag="VB649_001829"
                     /pseudo
     CDS             237..1259
                     /locus_tag="VB649_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1317..2395)
                     /locus_tag="VB649_001830"
                     /pseudo
     CDS             complement(1317..2395)
                     /locus_tag="VB649_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000459849.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
BASE COUNT          770 a          490 c          395 g          740 t
ORIGIN      
        1 tttatggtta tttaattttt ttattattta tgtaatatag tcattaaaag ttgaagtgat
       61 ttataaaaat aagagattga catactactt gtaagtcgtt aatcactagt ataagtgtag
      121 ctagtgtatt tcagaagaca aaaaaatccc ccgcgttgta aaatgaagtg caacaaaaga
      181 gacatgttcg tttgatatac tagaattccc caactcagta tagaaagcag atgaacatgt
      241 ccactaatta ttctaccaaa aacgcctctt attcacacct ctcagcctcc gagcgaggag
      301 aaatcagtgc ttatctaaaa atggggaaga aaccatctga aattgctcga ctactaggtc
      361 gtcaccgttc taccattact cgtgagatta aacgtggtac agttactcaa gttcaagata
      421 agaatgggaa acgaacttat tatgaagctt acttcgctga tagcggtcaa cgggtctacg
      481 aagaaaaccg taagaacagt gtctatctga aattagacca gtgctcacca cgcttcttta
      541 aagatctaga gaaagctgtt aaagccaacg ttcgtcgtca tagtgtggat acttttgtcc
      601 acgactataa agagaagcat ccaacagaga ctattccatc aacgaagacg ctatatcgct
      661 acattgcggc tggtctcatc tctatcaatc caatcgattt gccaaagatg gtcagtatca
      721 gaacacggtc taaatccaaa accacgatca ataagaagaa ccttggaaaa tccattgaag
      781 agcgtccagg ggcaattaat gaccggtctg aatttaggca ctgggagatt gacttggttt
      841 tgggtaaaaa gaccaaggga gaggcggctc tcatgacctc ggttgaacgt caaactcgtt
      901 ttgccttagc ctgtaagtta ccaaataagg aagcccaaac catcaatgaa gctgtcaagg
      961 aactcttggt tgagcatccg attacttcta tcacatcaga taacggctct tagtttagtc
     1021 tcttgtctga tttagatgac gttgatagtt acttcgccca tccctactca tctcatgaaa
     1081 gaggaacaaa tgaaaacttc aacgggctcc tcagagaatt tctctctaaa gggaaatctc
     1141 tcaatccgct gactgatgga gaactcgcta aatatctctc agctatcaat gagcgaccta
     1201 gacgacttca ccattacaag actgcaacat ttctgtttgg gttagcccaa acagtctaag
     1261 ctatggaata ctagcttatc agtgaacttg ttgcacttga cttgacaata ctccaactta
     1321 tttctatcga tgatttgttt aaatttttca ttgaaacagt atccaaaaca taaatcattc
     1381 gaagttattg tgtaactact tcctttatca aatgcttcaa gttcaaaagc aaagttatgg
     1441 catatatcta tcatcaagat aattatatac accatttgct tccttaaatc ctaaatcaat
     1501 cattctaatt ttagtagcct gtctagatac ctcaaagaag gtagctaagt tgtctaccac
     1561 ttcttgcact aattcagaac gacttatatc aggattaacc aatgtcaaag tttgaaatag
     1621 ctccctaatc tttattctag tttggacttt gggcataaga attcggggag taattccatt
     1681 agcttgccac tccatccagt cgagcgacgt ccacatacta gaatcagcta aattttcttc
     1741 tgtccagcta ctaacttgtg agtagtcctt atcaagtacc atcttgactt cgtgaaatac
     1801 tttatgaagt tcccagtgaa tacattcatg gatgaccgta ttgttatacg aacctacatt
     1861 ccgtttgaaa acaacatcct tatctacaag gatactccct ttgttaaaat gcttagaaac
     1921 taactgctca tcctctatga cctcaacatc agtatcttta aaaaccattt tcccgaaaac
     1981 tgaattatct atagttagtt tctcttgatg gatagacagt cccatttcag aaactattgt
     2041 ctcaactgga acaggggttg aggatagtac ttccttaaga atttttcagc aatatcatca
     2101 aagtccttct tccttatata tggaacccag tctttactca attttaagtt tcgggacttt
     2161 ttgtactgat ctgatttaaa ttctgtattg taaattcgaa agtttttgat accagcatca
     2221 agttctactt cagcatatac agacacaaac ttaggtttag tatcagtctc catctcacct
     2281 ttgatatact gtcgaaaaat tacattagca atcacaatga tttcaagatt taattcgcaa
     2341 ttattaataa tttcatagtt tatcttatat aactcaaaat tatcaaactc aataa
//
LOCUS       DATTYN010000065         2327 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.65, whole genome shotgun sequence.
ACCESSION   DATTYN010000065 DATTYN010000000
VERSION     DATTYN010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2327
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.65"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..228
                     /locus_tag="VB649_001831"
     CDS             <1..228
                     /locus_tag="VB649_001831"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HEP1670749.1"
                     /translation="NKLWLGDLTYIPTQEGILYVSVLIDVYSRKIVGWAMGRRMQDKL
                     VTEAFNQAYNREKPKEGVIVHTDQGSQYTGA"
     gene            253..483
                     /locus_tag="VB649_001832"
                     /pseudo
     CDS             253..483
                     /locus_tag="VB649_001832"
                     /inference="COORDINATES: protein motif:HMM:NF025063.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            698..2174
                     /locus_tag="VB649_001833"
                     /pseudo
     CDS             698..2174
                     /locus_tag="VB649_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT          722 a          451 c          490 g          664 t
ORIGIN      
        1 aataaattat ggctaggaga cttaacctac attcctacac aagaaggaat actttatgtg
       61 tctgtcttga tagacgttta tagtagaaag attgttggtt gggcaatggg ccgacgtatg
      121 caagacaagt tggtaacaga agctttcaat caagcttata atagagaaaa gcctaaagaa
      181 ggggtaatcg tccatacaga tcagggttct caatataccg gagcatgatt tcaggaccta
      241 cttagacgga aaaaatgtaa gtccagtatg agtcgaaaag gtaatccata cgataatgca
      301 ctcatggaat ccttttataa aacattaaaa agagagcttg tcaatgatgc tcatttcgca
      361 actattgagc aacctcagct tgagattttt aaatatagtg agacttacta taaccctaaa
      421 cgtctgcctt cagctttagg gtatctctca cctgttgaat ttgaaaaaat agttactcat
      481 tagcttaact ttatgtctat tttttcttga caagtccaac attcagcaag tgtctttaga
      541 tgctgctggt tttcaatgcc ttacaggagg tgtacaagcc acccgttttc acgggtgctt
      601 tcagactgaa gacaaagtcc ttagaatcac ttttctaggg ggcttttcat gatatttagg
      661 agtataatat aagaaaaagg acttgtgagg ttctcctatg ttacacaaag aaaaacctga
      721 ttataaccgc aatcagtacg gtttctatac ccttgaccag ttagtgcctg atgaacattt
      781 cctgcgccaa gtggaagctg tgattgcctt cgacttcatc tatgacctag tagaagacac
      841 ctattcgtct gataatggtc gccctagcct tgatcctgtc atattggtta aaatccctct
      901 gattcagtgc ttttatggca ttcgttccat gcgtcagacc atcaaggata ttgaagtgaa
      961 tactgcctat cgctggtttt taggtttgac tttggatgac aaggtgccac atttcacaac
     1021 ctatggcaaa aattattccc gtcgctttca agaaaaaggc ttgattgagt ccatttttac
     1081 gcatattctt gggctatgta tcaatacaga cctgattgac ccgacggaga ttttcataga
     1141 tgggactcat atgaaggctg cggctaatac tcgcaagttc atcaaccgag aggtggaaaa
     1201 acaagccaag ttcatgagtg aacagctaga aatcgaaatc aatcgggata gggagaagca
     1261 tggaaaaaaa gccgctaggg cccgccaaag agctagagcc cgtcgctaag aaaatctcca
     1321 caaccgatcc agaaagtggc tggtttcaca gatcataagg aagtcttcgc ttattctgct
     1381 caggtggctt gtgacaagta tggatgggcg cttgcttata gtgttgaggc tggcaatatc
     1441 catgatagtc aggcttttcc tgcacttttt gccaagcttg aacccttgaa accacagttt
     1501 attattgcgg attccggcta taacatttcc agcattgcca agtttctgat tgataaggag
     1561 atcactcctg tccttcctta cacacgacca agaggaaaga aagaccttct acgtccgaaa
     1621 gaattgattt atgatgagca ctttgattgt gtcatctgcc ctgaacatca agccttgacc
     1681 taccgcacta cgaccagaga aggctaccga gaatacaaaa gtgaccctgc aatttgtgcc
     1741 aattgtcccc tgttatctgt atgtacgacc agtaagaacc accaaaaagt tgtcacacgg
     1801 catatttgga aagactattt ggaacagtgc gaggacattt gtcatcaaag ggggatgaag
     1861 gagctctacc agcatcggaa agagacgatt gaacgactgt ttggcacagc caaggaatgc
     1921 cacaatctcc gctatacgag agagaaaggc aagtccaaaa tggaagataa ggttggagtg
     1981 actttggcat gcttaaatct caaaaaactg gtcaaaagga tggcgggaga gcctttttat
     2041 tttgttcaga tgaggtggtt taagcacgga aacagccatt tttatctaaa aacactaaaa
     2101 aagacaaaca ccaaatcgat gtttgtcttc aatctgaagc cacccgtttt cacgggtggt
     2161 ttttatttat ataaagctat cagataaaag tagttttttt gaaaaaaaca tttcattgaa
     2221 tggttaattg tatatattgt acagcataca attgcagcaa tgaatagtga ttaatgttaa
     2281 atggatttaa gtatcttata attatagatt ccttagtgat atgtaaa
//
LOCUS       DATTYN010000066         2313 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.66, whole genome shotgun sequence.
ACCESSION   DATTYN010000066 DATTYN010000000
VERSION     DATTYN010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2313
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.66"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            148..>2313
                     /locus_tag="VB649_001834"
     CDS             148..>2313
                     /locus_tag="VB649_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944926.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEP1670750.1"
                     /translation="MLRKYKQRNYDVAHTKQRFSIKKFKFGAASVLVGLTFLGMSSHS
                     VLADESSIMSTEVPQTAGVKPEVTVTQPTSDVTSLATDTSTSAVLSTDASHSNPTGSA
                     EHAVGMNAENVAVPVTNDKEAKKTLPVTSSSTSEFTEQKDTAENQDSENRVSSSKQVE
                     AVKDGQTATQSVSRSHMSNIKDVNIENMTFADLKKLANIDNLSAVDFKKHPQLKAIFE
                     QVVQNSPEVSNWPKVGGLSARDYILANGIDSYREQLGHIRRQTVLAQSINDKTVRRKE
                     DSIAPIDASKDKTTVRGTGYGFGGTPLHYTIETERKGDKIDVTVTYEVDGQSKETFRN
                     DFFFYAGGGFDTQKPINVSVTTEGLKNGADSKNTELGKGYSSQANGAFGLKTTINFPP
                     YSHNNKGKQIYKFSLPIKDVNGDLSLRMMVTAYNAQTGGNQTNDPYSNDNYYYGNAPF
                     DADFNPNYRGGTTQVTEEIPPSTLYIPTTTLKEGETEVVSEGTLGTKTTTYRTHQFGN
                     QTFLGLPIGKPEIKEPSPRIVKVGISQENMSQFPRGPKGDRGETGPAGERGEQGPKGD
                     AGAQGPMGPAGPAGERGEKGEQGKQGLPGTPGLKGDRGETGPAGKDGVIPTITTKPGK
                     DGNSTDVTITIPGKEDTTINIKNGRDGLDGKTPKVDSLRLEEQGITVLTFYIDKDDDG
                     KYTPGVDDIIQSELIKDGKDGKDGKTPTVEQTPIKDATGK"
BASE COUNT          843 a          395 c          490 g          585 t
ORIGIN      
        1 tatcgaatat aattatacaa tacaaattca aataatagtt cacatttatc gaaataatgt
       61 aaaccagtaa aacttttaaa aaagtaaagt tatctataga taactttatt ggttaatcta
      121 tttttacttt tgaaaaggag agaagttatg cttaggaagt ataagcaaag aaattatgat
      181 gtcgcacata cgaaacagcg cttttcgatt aagaaattta aatttggtgc agcatcggta
      241 ctggttggat tgacctttct aggaatgagt agtcattctg ttttggcgga tgagtcaagc
      301 attatgagta cggaggtacc acaaacagct ggtgtaaaac cggaagttac tgttacacag
      361 cctacttcag atgtaacaag tcttgcgaca gatacgtcaa cttcagcagt gttatcaaca
      421 gatgcatctc attctaatcc tacaggatca gcggagcatg ctgtaggtat gaatgctgaa
      481 aatgtagcgg taccagtgac aaacgacaag gaagcaaaaa aaacgttacc agttacttct
      541 tcttccacat ctgaattcac agagcaaaaa gacacagcag aaaatcagga ttcagagaac
      601 agagtatcat ctagcaaaca ggtagaagct gtaaaagatg gtcaaacggc gactcaaagt
      661 gtatcgcgta gtcatatgtc aaatattaag gatgtaaaca ttgaaaatat gacttttgct
      721 gatttgaaaa aattggcaaa tattgataat ctttctgcag ttgattttaa gaaacatcca
      781 cagttaaaag cgatttttga acaagtggtt cagaacagtc cagaagtatc taactggcct
      841 aaagttggag gactttctgc aagagattat atcctagcta atggtattga tagctataga
      901 gaacaactag ggcatattag aagacagaca gttcttgctc agtcgattaa tgacaagaca
      961 gttcgaagaa aagaagattc aatcgcacct attgatgcta gcaaagataa gacgacagtt
     1021 agagggactg gctatggttt tggtggtacg ccattacact atacaataga aacagaacgc
     1081 aaaggagaca aaattgatgt aacagtaact tatgaagttg atggccaaag caaggagacg
     1141 ttccggaatg attttttctt ttatgcggga ggtggttttg atactcaaaa acctataaat
     1201 gttagtgtta ctactgaggg attgaaaaac ggtgctgact ctaaaaatac agaattagga
     1261 aaaggttaca gttctcaagc aaatggagct tttggtctga aaacaacaat caactttcca
     1321 ccttattctc acaataacaa aggaaaacag atttataaat tttctttgcc tatcaaggat
     1381 gtgaatggcg acttatcatt gaggatgatg gtaactgctt ataatgcaca aactggtggt
     1441 aatcagacta acgatcctta tagcaatgat aattattatt atggaaatgc tccttttgat
     1501 gctgatttca accctaatta tagaggggga actacacaag ttacagaaga gataccaccc
     1561 tcaactttgt atattcctac aactacacta aaagaaggtg aaactgaagt tgttagcgaa
     1621 ggaacattag gaacaaaaac aacaacttat aggacacatc agtttggtaa tcagacattc
     1681 ctaggattac caattggaaa accagaaatc aaagaaccat ctcctagaat cgttaaagtt
     1741 ggaatatccc aagaaaacat gtcacaattt cctagagggc ctaagggaga ccgaggtgaa
     1801 accggcccag ccggagaacg tggtgaacaa ggtcctaaag gagatgctgg agcacaaggt
     1861 ccaatggggc cagctggacc tgccggagaa cgtggtgaaa aaggagagca aggtaagcag
     1921 ggtcttcctg gtactcctgg acttaaagga gaccgaggtg aaaccggccc agcaggtaaa
     1981 gatggtgtga ttccgacaat tacaaccaaa ccaggaaaag atggtaatag cactgatgtc
     2041 acaattacta ttccaggtaa ggaagataca accattaaca ttaaaaatgg acgtgatgga
     2101 ttagacggta aaaccccgaa agttgacagt ctcagattag aagaacaagg aattacagta
     2161 cttactttct atatcgacaa agatgatgat ggaaaatata cgcctggcgt tgatgatatc
     2221 atacaatcag aactcatcaa agacggtaaa gatggtaaag atggtaaaac cccaaccgtt
     2281 gaacaaactc caattaagga tgccacaggt aaa
//
LOCUS       DATTYN010000067         2222 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.67, whole genome shotgun sequence.
ACCESSION   DATTYN010000067 DATTYN010000000
VERSION     DATTYN010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2222
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.67"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(144..1478)
                     /locus_tag="VB649_001835"
     CDS             complement(144..1478)
                     /locus_tag="VB649_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEP1670751.1"
                     /translation="MIYLINTIVITLNVVVLLLIHARIFDYRMDTKKSLLGILTFYIC
                     SLLSTSLSNLLSVGFLGGLLLYPLFFLLYTRYIARRKVNGSLLLFYSLFPIAFWDVIH
                     SFIVYFIVFNISFLKNNYHSNIIIMIFSIVAGTMVLLLIQAFNYDFSHLRKKKLNQRT
                     RTIISIANFSMILYFITIPMIDFIEEVENINFTHYQEMITAIYFLLFICFVNLLDRNL
                     RQELQKQVVLQKELQLQNMARYSKQIEGLYQNIRSFRHDYANILTSLKIGIDCKDIEM
                     ISSIYHKVLKDSGKVLRGEKFNLARLRNINDLPLKSLLFVKLSEAQRLSIPVSIEIGE
                     PISIKNIELIDFLTLVSILIDNAIEGAAESGIVLCFFEQFGKQILIVQNDTFEKQINL
                     STIFERGVSSKGNNRGVGLSNVREILESYPTVTLKTVSNHFVFKQILEIEIL"
     gene            complement(1479..2222)
                     /locus_tag="VB649_001836"
     CDS             complement(1479..2222)
                     /locus_tag="VB649_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEP1670752.1"
                     /translation="MFVLEDDFLHQTRIEKIIYKILTDNKLEVNHLEVYGKPNQLLED
                     ISERGRHQLFFLDIDIKGEDKKGMEIAVEIRNKDPHAVIVFVTTHSEFMPVSFQYQVS
                     ALDFIDKELPEELFSHRIEKAITYIQDNQGKTLAEDSFVFTNVKSQIQVSFSDLLYIE
                     TSLIPHKLILYSTKQRVEFYGQLSEIVEQDDRLFQCHRSFVVNPYNISSIDRSERLVY
                     LKGGLSCIVSRLKIRSLIKVVEELHTKEK"
BASE COUNT          803 a          369 c          300 g          750 t
ORIGIN      
        1 cttctaaaat aattttaaaa tataaactag taattcatca ttcataaaag cttccaagag
       61 tctttagcag gtttagccta ctacagaccc ttggaagctt ttataaatat tttattttag
      121 tgataaaaaa gaaaagtatt acattatagg atttctattt ctagaatctg tttaaaaaca
      181 aaatgattac ttactgtttt gagggtaaca gtgggatatg attctaatat ctccctaaca
      241 tttgataaac caactcccct attatttcct tttgaagaaa cacctcgctc aaaaatcgtg
      301 gaaagattaa tctgtttttc aaaagtatca ttttgaacaa ttaatatctg tttaccaaat
      361 tgttcaaaaa aacaaagaac tattcccgac tctgctgcac cttcgattgc attatctatc
      421 aagatagaaa caagggttaa aaaatcgatt aactcaatgt tttttataga aatcggttcc
      481 ccaatttcta tagatacagg tatggataag cgttgagctt ctgataattt aacaaacagt
      541 aaacttttca gaggaaggtc gtttatattt ctcagccttg ctagattgaa tttttctccc
      601 cttaaaacct tccctgaatc tttcaacacc ttatgataaa tgcttgaaat catttcaata
      661 tctttgcaat caatgcctat tttcaagctt gttaaaatat ttgcataatc atgtctaaaa
      721 cttctgatat tttgatacag tccttcgatt tgcttactat agcgagccat attctgtaat
      781 tgtaactctt tttgtagaac aacttgcttt tgtaattctt ggcgtaagtt ccgatccaat
      841 aaatttacaa aacaaataaa taaaagaaaa taaattgctg ttatcatctc ttgatagtgc
      901 gtaaaattaa tattttcaac ttcttcgata aaatctatca ttggaatggt aataaagtac
      961 aatatcatgc taaagttggc aatagatata atcgttctag tacgttgatt tagtttcttt
     1021 tttcttaaat gactaaagtc ataattaaaa gcttgaatca gcagcaaaac catagtacca
     1081 gcaacaatag aaaaaatcat aataatgata tttgaatggt agttattttt tagaaaagaa
     1141 atattaaaaa caataaagta aacaataaaa ctatgaatta catcccaaaa agcaatagga
     1201 aacaaactat aaaataaaag aagtgaacca ttgacctttc gtcttgcaat ataacgagtg
     1261 tataacaaaa aaaataatgg ataaagtaat agtcctccta aaaaacccac tgatagtagg
     1321 ttggataaag aagtagataa aagagaacag atataaaatg ttaaaatccc taataagctc
     1381 ttttttgtgt ccatacgata gtcaaatatt ctcgcatgaa ttaacaatag cacaaccaca
     1441 ttaagtgtta tgactatcgt attaattaaa tatatcaact atttctcctt agtgtgcaac
     1501 tcttctacta cttttattaa tgatcgtatt ttcaatctcg aaacaataca agataatccc
     1561 ccctttaaat aaactaaccg ttcggatcta tctattgatg atatattata gggattgaca
     1621 acaaaggaac gatgacattg gaataatcga tcatcttgct caacaatttc tgataattga
     1681 ccataaaatt ctactctttg tttagtagaa tagagaatga gtttatgggg aattagtgag
     1741 gtttcaatat acagcaaatc tgaaaaggag acttgtatct gggactttac attagtaaaa
     1801 acaaatgaat cctccgctaa cgtttttcct tggttatctt gtatataagt tatagctttt
     1861 tcaatgcgat gactaaataa ctcctctggc aactctttgt caataaagtc taaagctgaa
     1921 acctggtatt gaaaagatac cggcataaat tctgaatgtg tggtcacaaa aactatcact
     1981 gcgtgcggat ctttatttct aatctccaca gcaatttcca ttcctttttt atcttctccc
     2041 ttaatgtcaa tgtcaagaaa aaaaagctga tgtcttcctc tctctgatat atcttcaagc
     2101 agctgattgg gtttaccata aacttccaag tggttaacct ccaacttatt atcagtcaaa
     2161 atcttataaa taattttttc aattctggtt tgatgtaaaa aatcgtcctc taagacaaaa
     2221 at
//
LOCUS       DATTYN010000068         2178 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.68, whole genome shotgun sequence.
ACCESSION   DATTYN010000068 DATTYN010000000
VERSION     DATTYN010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2178
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.68"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(497..1174)
                     /locus_tag="VB649_001837"
                     /pseudo
     CDS             complement(497..1174)
                     /locus_tag="VB649_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294537.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(1177..2040)
                     /locus_tag="VB649_001838"
     CDS             complement(1177..2040)
                     /locus_tag="VB649_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEP1670753.1"
                     /translation="MRDVYTKVTQIAREQLYQFMKDNQVSPLNYHFHYYFDDCIQKFG
                     IKVMEHHFTNRKIEGLTMIDEDGISISYESQNLQVKQNFTKCHELGHYILGHSGKQFT
                     QLSSKKDTVEESEANLFSAYILMPDIVLLSKIYYRLDSFKQVMTELSVSADALKFRLQ
                     DLFRYRLKRDNQEISSAIYQYQKGQSKPVLSLFEEAHIEIEDEYRAVEKDVLAKILNR
                     LRECYFVASTEFPELLENSFRKELEKEDNIDTWLEYDFWQSVGYAWRTDKLTAKQVKL
                     RAKTILLLEKR"
BASE COUNT          647 a          434 c          333 g          764 t
ORIGIN      
        1 gttagaataa aatacattaa caatattatc cttccaaatc atattatctc ctactgaaaa
       61 tacaacctca ttagttacta atttagacgg atgaattgac atatagtacc ctagcaactc
      121 aagctgctgt aaacttgggg atgatctacc actagaccaa ttcttcaata tatttaatga
      181 tatattagga tcatttatgt atttagctat tgcccttaat gattttagtt ttgaattttc
      241 ttgtccataa aaactataaa tattgttcat aacaatattt gtactgctct gcttttccat
      301 attcttattt tacatcgaaa aatattattt tttataacgt ttttttacac catgtttttt
      361 tatttgtaaa atataaaaat cgtaccatct atgatacgat ctaaatatct tttatatcaa
      421 tcaaaagctt atttacaatt taacatggat aacttaacat tatccttttt gacgtttcgg
      481 tgaaatttag attactttat acctccaaag gggtaaaact gcctacaatc tttccgacta
      541 ctcgtggatt ctcatcgaat ggcgcaaact tatcagggta atccttattg attgacacta
      601 agcggagccc ttcttcttct caatagactt tcttgatgta ggtctgtgaa tcccagacaa
      661 cagcataaac tgccccatca taatcgaagc ctgtttctct gataagagct acttctccgt
      721 tttgataagt tggttccatt gaatttccat caacccaaga ggcaaaatca tgtggcaact
      781 cttcattgta ataaaccacg tcatagtcca ggtcgccata aacagaggca ccgatacctg
      841 cagaaagttt ctcgtaaacg tggtactctg aacgcttttc tgcaatgctg ataaccttct
      901 gtgacgatac taggtcacga acataggtga tggctttttc ttgatttggt tccgtcagtt
      961 gcttataaat ggatgagatt tcgtcttcac tcaaataacc ttctggaacc tttaggactt
     1021 tttccaactt agcaatatta actttagttg gttttgacaa gcctttttcc catttgaagt
     1081 aagcctgctt tgaaactccg ataagctcag ccaactcttg ttgatctaag cctagttctt
     1141 ctcgtttttg ttttaattta tcaggttgat acataactac ctcttttcta ataggagtat
     1201 tgtttttgct cgtaatttta cttgttttgc ggtcaactta tctgtacgcc aggcgtagcc
     1261 tactgactgc caaaagtcat actctaacca agtatcaata ttatcttctt tctctaattc
     1321 cttgcgaaag ctattttcta gcaactcagg gaactctgta cttgccacaa aataacactc
     1381 tctcaggcga ttcagaattt tagcaagaac atccttttcc accgctcggt actcgtcttc
     1441 aatctcgata tgggcttctt caaaaagact gagaacaggt ttgctttgac ccttttgata
     1501 ttgataaatg gctgagctaa tctcttgatt atctcgtttc aaacgatagc ggaataaatc
     1561 ttgtaatcga aatttcaagg catccgctga tacggataac tctgtcatga cctgtttgaa
     1621 actatccaag cgataataga tttttgacag caagacaata tcaggcataa gaatataagc
     1681 agagaaaaga ttggcttcgc tttcttcaac tgtatctttt ttactgctta attgtgtaaa
     1741 ctgcttacct gaatgtccca agatatagtg acctagttca tggcacttgg tgaagttctg
     1801 ctttacttgc aggttctgac tttcatagga gattgaaata ccatcctcat caatcatagt
     1861 aagtccttca atcttccgat tggtaaagtg atgctccatt accttgatac cgaatttctg
     1921 gatgcaatca tcgaaatagt aatgaaagtg ataattcagg ggtgacacct gattatcctt
     1981 cataaattga tatagttgtt ctcttgcaat ttgggttact tttgtataaa cgtctctcac
     2041 agtacacctc ctcacaattt tatcagtcaa ctatttggtt gactaaaatt atataaaaaa
     2101 aaatggacga atgtccacta aaaattagtt taacaactaa cacatttgtc ttgcaactag
     2161 atttaaatcc tattatta
//
LOCUS       DATTYN010000069         2069 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.69, whole genome shotgun sequence.
ACCESSION   DATTYN010000069 DATTYN010000000
VERSION     DATTYN010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2069
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.69"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            222..449
                     /locus_tag="VB649_001839"
     CDS             222..449
                     /locus_tag="VB649_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEP1670754.1"
                     /translation="MEIKKLETFHQMTIEKFAKVEGGKNNWQANVSGVIAAGSAGAAI
                     GFPVCGVACGYIGAKTAITLWAGVTGATGGF"
     gene            462..662
                     /locus_tag="VB649_001840"
     CDS             462..662
                     /locus_tag="VB649_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEP1670755.1"
                     /translation="MTTMKELTINDMASISGGNAPGDAVIGGLGGLASGLKFCKLPHP
                     VLTGGCVVGFTVGGAYLGYTAN"
     gene            1201..1482
                     /locus_tag="VB649_001841"
     CDS             1201..1482
                     /locus_tag="VB649_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670756.1"
                     /translation="MKTLDIIFNLSDRKMIFLENVEKLGGYIVPFTLIILSVAYNFRH
                     PYPIWAAVLGGISLIMIFIYFILIVYLYLRYRYLVWKKIPEIKINFTEL"
     gene            1676..>2069
                     /locus_tag="VB649_001842"
     CDS             1676..>2069
                     /locus_tag="VB649_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670757.1"
                     /translation="MRNILRFLGIVIISAVILFSIGSFYDLPLMKNIQLICWSFILDL
                     FVFVYKQRQTTEVLTWYQVVKQFWLFIKCTILIPTLIAFIIIIGCLTSISEVSIYFYL
                     HLIVVCYTIGMILSLGRLISPNHSIFNKL"
BASE COUNT          680 a          264 c          405 g          720 t
ORIGIN      
        1 tcaaaaatct taaaaggtat ttataaaagc atgaatggta ttatttaaac ttcttaatta
       61 actattgtca cagcgtaagt gtagagagga taaaaagaca tttcatgatg aaaaacagcc
      121 ttttaagatt ttgaaaccat gatactgttc tttatgatat tctgtactag tcgaggttgc
      181 aacgagacaa atttaagaat tatgaaaaga agttattcga tatggagata aagaaactgg
      241 aaacatttca ccaaatgact atagaaaagt ttgccaaggt tgagggtggt aagaataatt
      301 ggcaggcaaa tgtcagtggg gttatcgctg caggtagtgc tggagctgct ataggttttc
      361 cagtttgcgg tgtagcctgt ggttatattg gagctaaaac agctattact ctttgggctg
      421 gtgtaacagg agctacaggc ggattctaga ggaaagaaag gatgacaaca atgaaggaat
      481 taacaattaa tgacatggct agtataagtg gaggaaacgc tccaggagat gctgtaattg
      541 gtggtcttgg aggcttagct tctggattga aattttgtaa actgccacat ccagtattga
      601 caggtggatg tgttgtagga tttacagttg gtggagcata tttgggatat acagcaaatt
      661 aaatgatcta tacgattttt attattatga atgcgtctat aatgttttta atcattgttg
      721 atgccattca taaaaaaatg ttgataaatc tataccatat ttagtgtttt taattttcaa
      781 tcaattatcc ctttcagaaa aatcggtaaa catgttatct atcgtagctt tggtagcgtc
      841 attatttgtt tttatcgata aaagaaaata gtgattatgc caatgaattt agatatcact
      901 cttagctttt taaaatacaa aagagtgaaa ttaaaatgaa aaagacttca aaaatatgga
      961 agtgctaaaa aaatggtctg gctatcataa atggaggcgg aaaagacgga gcaaatatct
     1021 ttttgacagg gatggcaggt gctgcgcagg gagtgacagt ttgtgctcag acaggcgtat
     1081 ttatcccttg gcaaggttat tttttgtgtg gagcagctgg tgctgctaca aatattatct
     1141 ggcctcacta aatatataaa tgactatcta tcactgatgt ataagtagta gaggagtggt
     1201 atgaaaactt tagatattat ttttaaccta tctgatagaa agatgatatt tctagaaaat
     1261 gttgaaaagc tgggaggtta cattgtccct tttaccctta tcatcttgag tgtagcctac
     1321 aactttaggc acccttatcc tatttgggct gctgtactag gaggtatatc ccttattatg
     1381 atctttattt attttatact tattgtttat ctatatttgc gttatagata cttggtatgg
     1441 aaaaaaatac cagaaattaa gattaatttt actgagctat aatgcaatca catttaaggg
     1501 gaaaatggat tacttataca atatcagtac ttatgatatt taactttaga gactaaaaag
     1561 ttaaaagcaa aatgcgtatt gaaaattggt taaaaaagtt ataactgtct ctgataacag
     1621 gaataacaat ttgttcggtt atatttgcta ccgatagagt agaggaggtg aagatatgcg
     1681 taatatatta agatttttag gtattgttat tatttctgca gtgattctat ttagtatagg
     1741 tagtttctac gatttaccat taatgaaaaa tatacaactt atctgttgga gttttatcct
     1801 tgatttattc gtttttgtct acaaacaaag acaaacgaca gaagtgctca catggtatca
     1861 agttgttaag caattttggt tatttattaa gtgtactatt cttattccta ccttaattgc
     1921 ttttattata ataataggat gtttgacgag tatatcagag gtatcaattt acttttattt
     1981 acaccttatt gttgtttgct atacaatagg aatgatttta tcattaggtc gtcttatttc
     2041 tcctaatcac tctatattta ataaactta
//
LOCUS       DATTYN010000070         1847 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.70, whole genome shotgun sequence.
ACCESSION   DATTYN010000070 DATTYN010000000
VERSION     DATTYN010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.70"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            92..>1847
                     /locus_tag="VB649_001843"
     CDS             92..>1847
                     /locus_tag="VB649_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEP1670758.1"
                     /translation="MKKKINSQKSIELITNALQNIENHIPNEMRKTYSFKGRKSPEII
                     SKILEALTKTNDIIFDPFIGSGTSIIGSHLAKRHLIGTELDPFTFAIDKVLFEKINKV
                     ELEHNIKLIEDAVKSYILSLYETECCGETNYIKKVLFDPQNGKDGYLYPVENREIKNG
                     KNVKLLDKCSICGASDKHFTEEDWLNIQEQMKMSTDGFPTDRLIENSRINITRSTGAD
                     RYDIFFSHRNKLALLALQESISKLKPSKSKDFLQYCLVSSLSLAKIAMYGSSTDILYH
                     VVLEKAQDMNVWYLFEQKIKSFSNFQKKFENALVENFSSSEEYAVFNMDYSSYLKVNP
                     NLKVDAIFTDFPYTDQVPYLERNQLFRIWLEHFADNRNSFSLSQKMLGDEIVVTNAPS
                     RRDKNLDNYIIDLDKMFYNFEKILPEGGHVVFLTKLGKKKYFNVFGKIIDRARKNGFE
                     HLSRVSIEKKDPTLRKQSAFRNTLINEVVIVFQKLNSNDRYLYINNENYEAKIIDFVY
                     RTVKSLKDDSITVTELVYNICREITQLGEHVTPQITKRIHEIIDHNFYISVNQEVQLS
                     KNVLYLDQEDDSTLFKKLY"
BASE COUNT          691 a          240 c          320 g          596 t
ORIGIN      
        1 ttgagaagga aaaattcaat taacttaaac aaaattgata agatttctga aatattaggc
       61 atcacaacag ctgatttatt agaggtagat aatgaaaaaa aagattaatt cacaaaaaag
      121 catagaacta ataacgaacg cacttcaaaa cattgagaat catattccaa atgagatgag
      181 aaagacctat tcgtttaaag gaagaaaatc tccagagatt atttctaaga tacttgaagc
      241 gttaacgaaa actaatgata ttatttttga cccttttatt ggcagtggta catctataat
      301 tggtagtcac ttggcaaaac gtcatcttat tggaacggag cttgaccctt ttacatttgc
      361 aatagataaa gtattatttg agaagataaa taaagtagag cttgaacata atattaaatt
      421 aattgaagat gctgtaaaga gctatatact ttctttgtat gaaacagaat gttgtggtga
      481 aactaattat attaaaaaag ttttatttga tccacaaaat ggtaaagatg gatatttgta
      541 tcctgtagaa aatcgagaga taaagaatgg aaagaatgta aagttgcttg ataaatgttc
      601 gatttgcgga gctagtgaca agcacttcac tgaagaagat tggttaaata ttcaagagca
      661 aatgaagatg tctacagatg gctttccaac agatcgacta attgaaaata gtcggattaa
      721 tattactcgc tctactgggg ctgatagata tgatatcttt ttttcccaca gaaataaact
      781 tgcgctatta gctttgcaag aatctatttc gaaattaaaa ccatccaaat cgaaggattt
      841 tttacaatat tgtttagtat cttcgttaag tttagccaaa attgcaatgt atggcagttc
      901 tacagatatt ttatatcatg tagtgttgga aaaagctcaa gatatgaatg tatggtactt
      961 gtttgaacaa aaaatcaaaa gcttttcaaa ttttcagaaa aaatttgaaa atgcacttgt
     1021 cgaaaatttt tcgagctcag aagagtatgc agtatttaat atggattatt catcttatct
     1081 taaagtaaat ccaaacctta aagtggatgc tatttttaca gattttccgt atactgatca
     1141 agttccctat ctagaacgaa atcaattatt tagaatttgg ttagaacatt ttgctgataa
     1201 tcgaaatagt ttttcattat ctcaaaaaat gcttggcgat gagattgtcg taactaacgc
     1261 tcctagtcgc agagataaaa atctagacaa ttatatcatt gatctagata agatgttcta
     1321 caattttgaa aaaatacttc cggaaggtgg acatgtagta tttttgacta aattaggaaa
     1381 aaagaaatat tttaatgttt ttgggaaaat tattgatcgg gcaagaaaaa atggttttga
     1441 gcatctatcg cgtgttagta tcgaaaaaaa agatccaact ttgagaaagc agtctgcttt
     1501 ccgtaatact ctgattaatg aagtagtaat tgtgttccaa aagctaaata gcaatgacag
     1561 atatctatat ataaacaacg agaactatga agcgaaaatc attgattttg tctatagaac
     1621 tgtcaaaagt ctaaaggatg attcaattac tgttactgaa ttagtttata atatttgtcg
     1681 tgaaattact cagttaggcg aacatgttac accacagata accaagcgga tacatgaaat
     1741 aattgatcat aatttttata tttcggtaaa tcaagaagtt cagctgtcaa aaaatgtact
     1801 ttatctagat caggaggatg attctactct gtttaaaaag ttgtatg
//
LOCUS       DATTYN010000071         1784 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.71, whole genome shotgun sequence.
ACCESSION   DATTYN010000071 DATTYN010000000
VERSION     DATTYN010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.71"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            139..552
                     /locus_tag="VB649_001844"
     CDS             139..552
                     /locus_tag="VB649_001844"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670759.1"
                     /translation="MKLSIKTKLVISTAALALALPVGLHTYGTVTHASTYETTSLSEG
                     KNSFRREFDKKICKAYDHALEMATYGFNSYTGLVQHLKQSKEFVTGDTNTIEVAHNIL
                     EVAHKINPSLSTVDDFVKQIEEDYKRFEEEMVLYF"
     gene            663..1437
                     /locus_tag="VB649_001845"
                     /pseudo
     CDS             663..1437
                     /locus_tag="VB649_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001871253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          617 a          310 c          316 g          541 t
ORIGIN      
        1 gagggtgcac actatcagat tgttatattg taaaataatt attctttgtg aatcaaaaca
       61 tgatggcgtt cttataacag tatattaata ctatttgttt tagatgaact tagattacaa
      121 aaaagaatgg agaaaactat gaaactttct ataaaaacaa aactggttat ttctactgca
      181 gcacttgctc tggcattgcc agtaggactt catacctatg gaactgttac tcatgcatca
      241 acttatgaaa caacttcgtt aagtgaagga aaaaattctt tccgtcgtga gtttgataaa
      301 aagatttgta aggcatatga ccatgcttta gagatggcaa cttatggatt taattcatat
      361 actggtctag tacaacatct caaacaaagt aaagaattcg taacaggtga cacaaatacg
      421 attgaagttg cccataatat tctagaagta gctcataaaa taaatccatc tttatcaaca
      481 gtagatgatt ttgtaaaaca aattgaagaa gattataaaa gatttgaaga agaaatggtt
      541 ctatattttt gatgaaagct aaaaagtaat tttaacccgc gttgtaaaat gaagtgcaac
      601 aaaaaagaca tgttcgtctg atatactaga attccccaat tcagtatgga aagcagatga
      661 acatgtctaa tattaattct accagaaaat cctcctattc tcatctttca gccacagaac
      721 ggggtgaaat tgctgcttat cttaaaatgg gaaagaaacc cgttgagatt gctcgacttc
      781 tgggtagtca ccgttctaca atctgccgag aaataaaacg tggttcagca gatcaggtaa
      841 aggataagaa tggaaaacaa accttcttca acgcctattt cgctgatagt aggcaacgtg
      901 tctattaaac caatcgattt gcctaagatg gttagtatta gaaaacgttc taagaaagtc
      961 atgaaaacga ataagaagac tttaggtaaa tctatcgaag aacgtccaga atatattaat
     1021 gatcgttctg aatttgggca ttgggagatt gatttggttc tcggcaagaa aaccaaaggt
     1081 gaagctgtta tgttgacttt ggtagagcgc cagacacgct atgcactagg agttaagcta
     1141 gaagacaagc agtcccaaac cattaaccgc gctgtcacgc atctcatcag tcagtatcct
     1201 attgcatcca tcacagcgga taatggttct gagtttagtt tactctcaac cttagaagct
     1261 gttgacgttt actttgcaca tccctattct tcacatgaga gaggaacaaa cgagaacttc
     1321 aatggcctcc tcagagaata tggccctaaa ggagtctcac ttaatccact aacctctgaa
     1381 gaacttaaca attatcttac agccatcaat gagtgcccaa gacgacttct tcaatagcaa
     1441 tcctcaaaat tcctgtttga gctatcccga acagcttaac ctctggaact ctagttatct
     1501 atgaactcgt tgcacttgac ttgactactt gcgaaagtaa ttttataata gaatcaacaa
     1561 tttgtttaat tgacaacgag ttgtttgtgc agagcaacat tcagttattc ttgttgttaa
     1621 tcagtcatag tgtttattaa taaggctagc ctagcttaaa aaaatttagc tgtaagcaaa
     1681 attaaagtat gaagcgactt aaaattaact ttaaaaaaga ggaaatttta agtcattttc
     1741 tattttaatt tttgttagct atttatcggc taaatatatt tcta
//
LOCUS       DATTYN010000072         1652 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.72, whole genome shotgun sequence.
ACCESSION   DATTYN010000072 DATTYN010000000
VERSION     DATTYN010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.72"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(85..390)
                     /locus_tag="VB649_001846"
     CDS             complement(85..390)
                     /locus_tag="VB649_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEP1670760.1"
                     /translation="MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVL
                     LVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN"
     gene            complement(402..821)
                     /gene="ruvX"
                     /locus_tag="VB649_001847"
     CDS             complement(402..821)
                     /gene="ruvX"
                     /locus_tag="VB649_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012561069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEP1670761.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIKIDEEKAEFGFTR
                     LEELVKQYQVEQFVIGLPKNMNNTNGPRVDASITYGNHIEHLFGLPVHYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLNRNF"
     gene            complement(818..1087)
                     /locus_tag="VB649_001848"
     CDS             complement(818..1087)
                     /locus_tag="VB649_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEP1670762.1"
                     /translation="MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK"
     gene            complement(1201..1599)
                     /gene="spx"
                     /locus_tag="VB649_001849"
     CDS             complement(1201..1599)
                     /gene="spx"
                     /locus_tag="VB649_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEP1670763.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLAYKEQNLGKEPLTKEEILA
                     ILSKTENGVESIVSSKNRYAKALDCDIEELSVSEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENTEARLRAAL"
BASE COUNT          492 a          341 c          243 g          576 t
ORIGIN      
        1 ttatcacctc ctgcttattt attcgaaaat aacattaaaa aaatagccct cacggctact
       61 ttttaacata gtgtcactaa caatttagtt ctcatctaga aaactattaa atacctcttc
      121 aatcatatcc cattcagcat ctgaatcctc aggaatcggt tgtaaatccc cttcagtacc
      181 atcttcattt tcagtaaatg aataggcttg gatttcaatt tcaccagact catcttcttc
      241 agatcccgct ggaaccaaga gaacataatt tttaccaaac tcttcacgac cgtcaattgt
      301 taataaaatt tcaaacaagg tttcatttcc ttgttcatcc acaagtgtga taacttcgtg
      361 ttggtggtca ttttcatgat tatgtgtcat tttttatctc cttaaaaatt ccgatttaaa
      421 tagttctgta aaatgagttg tgcagctaat ttatcaatga ctttttttcg cttaccacga
      481 ctaatgtcag cttgctcaat aagcatacgc tctgcctcaa cagtcgtcaa tcgttcatct
      541 tgataatgga ctggaagtcc aaagaggtgc tctatgtggt ttccataagt tatacttgca
      601 tcaacacgtg gaccattggt gttattcata ttttttggca atccaataac aaactgttca
      661 acttggtact gcttaacaag ctcttctaaa cgtgtaaagc caaattctgc tttttcctca
      721 tcaatcttga taatttcaag tccttgggct gtaaagccaa gaggatcact aatagctaca
      781 ccaaccgttt tcgagccaac atcaagtccc attattctca tttaacatca attccatttc
      841 cttgtaaata gtagcgaaca agttcttcta caatttcatc acgttcatat ttacgaatct
      901 gatttcgagc atcattataa cgaggaacat aagctgggtc cccactcaag acataaccaa
      961 caatttgatt aattggatta taaccctttt catcaagtga atgatagact gctgttaatg
     1021 tttcactaat ttgtcgtttg tcgccatcat ccaacttaaa gcggactgtt tcatctgtaa
     1081 atcccatact tacaccttct ttctaaaatt aagtgctatg ctttattata gcttatttct
     1141 attaaataaa caagaatttc aagcgaagaa ggtatttaaa aaaaagctct acaagagctt
     1201 ttagagtgca gcacgtaatc gtgcttcagt attttcaata ttacgaatag agcgaggtaa
     1261 aaaagcacga atatcgtctt ctttgtagcc tacttgcaga cgtttatcat caatcaaaat
     1321 gggactttta aggatgcgcg ggttatcttg aatcaaatca ataacctcac taacacttag
     1381 ttcttcaata tcgcaatcga gagctttggc ataacgattt ttagatgaaa caatgctctc
     1441 cactccattt tcggtttttg ataaaattgc taaaatttct tctttagtta gcggttcttt
     1501 tcctaagttc tgttctttat aagcaagctt atgggcattt agccaagttt tggctttctt
     1561 gcagctcgta caacttgaaa tcgtgtaaat tttaatcatg ttgctgactc actttctatt
     1621 tcgtgatagc tttattgtag cacagtttct ta
//
LOCUS       DATTYN010000073         1373 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.73, whole genome shotgun sequence.
ACCESSION   DATTYN010000073 DATTYN010000000
VERSION     DATTYN010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1373
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.73"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(71..1192)
                     /gene="mnmA"
                     /locus_tag="VB649_001850"
     CDS             complement(71..1192)
                     /gene="mnmA"
                     /locus_tag="VB649_001850"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEP1670764.1"
                     /translation="MTDNSKIRVVVGMSGGVDSSVTALLLKEQDYDVIGVFMKNWDDT
                     DEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLS
                     QEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQ
                     KGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQ
                     GFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVTVHVRGDKAEVVFA
                     EPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI"
BASE COUNT          419 a          304 c          232 g          418 t
ORIGIN      
        1 ttttataaat aatatcatag tcaaaggaat tgttgaatgt ccctttcttt ttatcttaat
       61 aaaagattca ttaaatgtac tgacaaggct gcccattttt ataagccatg tcaatcatac
      121 caccaccaag gcattctttt ccgtcataga aaacaacagc ttgaccagga gtaatcgcgc
      181 gctgtggctc tgcaaaaaca acctctgcct tatctcctcg aacatgcacc gtcacgtgtg
      241 aatcgggttg acgatagcga aatttagcag tacattcaaa tgtgaactct tctggcatct
      301 cacgtgtaaa atggatgact gaggcgtcaa gactatttga cattagggct tcatggtaga
      361 aaccttgacc aacgtataaa atattttgcg acaaatcttt accgacaaca aaccaaggtt
      421 gattatcccc accatgctga ccaccaatgc ccagaccacc acgctgacca atagtataat
      481 acataaggcc ggcatgttct cccatatcgc gaccatcaat agtcatcatg cgaccttttt
      541 gtgccggtaa gtactggctc aaaaactgtt tgaaattctt ttcaccaata aaacaaatac
      601 ctgttgaatc tttcttttta gccgttgcaa gccctgctcg ctcagcgatt tctctaactt
      661 ctgacttttg caaatgacca agggggaata aagtcttttg tagttgttcc tgtgatagtt
      721 gacttaaaaa gtaggtttgg tctttgccat tatcagctcc acgtaacatg tgaaccgtac
      781 cattttcatc acgcttgact tgagcatagt gtcccgttgc tacataatct gcacctaaag
      841 tcatggcata gtcaaggaaa gctttaaatt ttatttcctt attacacatg acatcgggat
      901 ttggagtacg acctgctcgg tattcggcca agaaatattc aaatactctg tcccaatatt
      961 ctttttcaaa attgactgaa tagtaaggaa taccgatttg atcagcaacg gctgctacat
     1021 ctttgtaatc ttcagtagct gtgcaaacac caaattcatc tgtatcgtcc cagtttttca
     1081 tgaagacacc aataacatca taatcttgct cctttaaaag tagagctgtt acagatgaat
     1141 caacgccacc actcatacca acgacaacac gtatctttga gttatctgtc ataaaaaatt
     1201 ctcccatcaa taataagata gaaaaagata atcatcatat tatgaatatt atgattcttt
     1261 ttcttatcag ttaacgtacg attgaaggtc gtcgttttca aaagtcgatt tgaaggtcga
     1321 ttttgaagcg ccatcagcgc aaaccttatt ataacaatta ctgcgtggaa tgc
//
LOCUS       DATTYN010000074         1291 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.74, whole genome shotgun sequence.
ACCESSION   DATTYN010000074 DATTYN010000000
VERSION     DATTYN010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1291
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.74"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            273..389
                     /locus_tag="VB649_001851"
                     /pseudo
     CDS             273..389
                     /locus_tag="VB649_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611995.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(575..>1291)
                     /locus_tag="VB649_001852"
     CDS             complement(575..>1291)
                     /locus_tag="VB649_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEP1670765.1"
                     /translation="EGINQELGKGITAINKAYRPGEGVKARKEAAKANLEKVAKETKA
                     LISGDRYLSETEKAVQKQAVEQALAKALGQVEAAKTVEAVKLAENLGTVAIRSAYVAG
                     LAKDTDQATAALNEAKQAAIEALKQAAAETLAKITTDAKLTEAQKAEQSENVSLALKT
                     AIATVRSAQSIASVKEAKDKGITAIRAAYVPNKAVAKSSSANHLPKSSDANSIVLVGL
                     GVMSLLLGMVLYSKKKESKD"
BASE COUNT          377 a          265 c          230 g          419 t
ORIGIN      
        1 gtgtaaacaa tcaagtagaa atgtctttat taagcgaatc aatcaaggtt gtagagtaaa
       61 tgctggacta gatttcatgt agaaattagt aaaagttagg agattttttg gtcgtttcaa
      121 acgataacat catcttctta taacaagaac ttcactcaga gataaactgt tctaatactt
      181 tagtagcctc ttttgagctt gtagcacgaa aattcgctcg aactgatgta aagtaggcat
      241 tttatctgcc cgcttgatcc ctactgcgcg accaagaaac cttttattca ctagaacaat
      301 taacccttaa aaccaaggag gaagtccact ggtggaacta ccatcacctt cacagtaatc
      361 ttaattatca aacacccata actaaatgag tcatcgtttg aacaaaaaac gccttataaa
      421 ttctgtacag aaaactgttg ccttttcaat tgaactttga aatgttttca atacactccg
      481 ttcttgggcc cttacgatcc aaaaaaccaa ggtgatttca aaatcacctt ggtttgaaaa
      541 tatagtagaa agcaatttgg ataaagccag gttcttagtc tttactttct tttttcttgc
      601 tataaagcac catacctaaa agaagagaca taactcctaa gccaacaaga acaattgagt
      661 ttgcatcact tgattttgga agatggttcg ctgacgatga ttttgcgact gccttattag
      721 gcacataggc tgcacggata gcagtaatac ctttatcttt tgcttctttc acagacgcaa
      781 tagattgtgc tgaacgaaca gtcgcaatag ccgtcttaag cgctaatgat acattttctg
      841 attgttcagc tttttgagct tcagtcaatt tagcatcagt tgtaatctta gcaagtgttt
      901 ctgccgcagc ttgtttaaga gcttcaatag cagcttgttt cgcttcgtta agagcagctg
      961 ttgcttgatc agtatcttta gctaaaccag caacatatgc tgaacggata gctacagtac
     1021 caagattttc tgccaactta acagcttcaa ctgtcttagc agcctcaact tgaccaagtg
     1081 ctttcgcaag agcttgctca acagcttgtt tttggactgc tttttcagtt tcgctcaagt
     1141 aacggtctcc tgaaataaga gctttagttt ctttagctac tttttcaaga ttagctttag
     1201 cggcttcttt acgtgcttta acaccttcac ctggacggta agctttgttg atagctgtga
     1261 tgcctttacc aagttcttgg ttaatgcctt c
//
LOCUS       DATTYN010000075         1196 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.75, whole genome shotgun sequence.
ACCESSION   DATTYN010000075 DATTYN010000000
VERSION     DATTYN010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1196
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.75"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..>1196
                     /locus_tag="VB649_001853"
     CDS             <1..>1196
                     /locus_tag="VB649_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEP1670766.1"
                     /translation="GVTSIKNQHKSGKGLDVRKDEHKKALEAVAKRVTAEIEADPTLT
                     PEVREQQKAEVQKELELATDKIAEAKDADEADKAYGDGVTAIENAHVIGKGIEARKDL
                     AKKDLAEAVAKTKALIIEDKTLTDDQRKEQLSGVDTEYAKGIENIAAAKDAAGVDKAY
                     SDGVRDILAQYKEGQNLDDRRNAAKEFLLKEADKVTKLINDDPTLTHDQKVDQINKVE
                     QAKLDAIKSVDDAQTADDINDALGKGIENINNQYQHGDGVDVRKATAKGDLEKEAAKV
                     KALIAKDPTLTQADKDKQTAAVDAAKNTAIAAVDKATTADGVNQELGKGITAINKAYR
                     PGEGVKARKEAAKADLEREAAKVREAIANDPTLTKADKAKQTEAVAKALKAAIAAVDK
                     ATTAEG"
BASE COUNT          430 a          233 c          276 g          257 t
ORIGIN      
        1 acggtgtaac cagcatcaag aaccaacaca agtcaggtaa aggtcttgac gttcgtaaag
       61 atgagcacaa gaaagctctt gaagctgttg ctaaacgtgt cactgctgaa attgaggctg
      121 atccaacctt aacaccagaa gtgagagaac aacaaaaagc agaggttcaa aaagagcttg
      181 aacttgcgac tgataagatt gctgaagcta aagatgcaga tgaagcagac aaagcttacg
      241 gtgacggtgt cacagcgatc gaaaatgccc acgttattgg taaaggtatc gaagctcgta
      301 aagaccttgc taagaaagac cttgctgaag ctgttgctaa gacaaaagct ctcattattg
      361 aagacaaaac gcttactgat gatcaacgta aagaacagtt atcaggtgtt gatacagagt
      421 atgctaaagg tatcgagaat attgctgcag ctaaggatgc tgcaggtgtt gataaagcat
      481 atagtgacgg tgttcgtgac atcctggcac agtacaaaga aggtcaaaac cttgatgatc
      541 gtcgtaatgc tgccaaagaa tttcttctta aagaagcaga caaagtgacg aaactaatca
      601 atgatgatcc aaccttgact catgaccaaa aagttgatca aatcaacaaa gttgaacaag
      661 ctaagttaga cgcaatcaag tctgttgatg acgctcaaac agctgatgat atcaatgatg
      721 ctcttggtaa gggtattgaa aacatcaaca accaatacca acatggcgat ggcgttgatg
      781 ttcgtaaagc gactgccaaa ggcgatcttg aaaaagaagc tgctaaagtg aaagctctta
      841 ttgctaagga tccaaccttg actcaagctg ataaagacaa gcaaacagca gcggttgacg
      901 cagctaagaa cacagcaatt gcagcggttg ataaagcgac aacagcagat ggtgttaacc
      961 aagaacttgg taaaggcatc acagctatca acaaagctta ccgtccaggt gaaggtgtta
     1021 aagcacgtaa agaagccgct aaggctgatc ttgaaagaga agctgctaag gttcgtgaag
     1081 ctatcgctaa cgacccaacc ttaacaaaag ctgataaagc taaacaaaca gaagctgttg
     1141 ctaaagctct taaagctgct atcgcagcgg ttgataaagc gacaacagct gaaggc
//
LOCUS       DATTYN010000076         1159 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.76, whole genome shotgun sequence.
ACCESSION   DATTYN010000076 DATTYN010000000
VERSION     DATTYN010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.76"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..1125
                     /locus_tag="VB649_001854"
     CDS             <1..1125
                     /locus_tag="VB649_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HEP1670767.1"
                     /translation="GLSIGLLLAKEHDVTFFDIDNKKIDLINKRQPPLKEAAINKLLC
                     KAKNINATSSEELAYKDATFIILSLPTNLKFNKLDTSIIEISVSNILKINKKATIVIK
                     STVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNESRNSQLFLDIL
                     TDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQNLDSKKIIEAM
                     GYDQRIGNSHNNPSFGFGGYCLPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKT
                     ILNSSAKTIGIYRINSKKDSDNCRESSTIDVAKLLKSSGKDVIIFEPLINQKKFLGCP
                     LINDFNEFIKYSDIIVANRIDDALRKCNSKVFTRDIFQYD"
BASE COUNT          428 a          164 c          183 g          384 t
ORIGIN      
        1 ggattatcga tagggctcct acttgcaaag gaacacgacg ttactttttt tgatattgat
       61 aataaaaaaa ttgatttaat aaataaaagg caaccccctc ttaaagaagc agctataaac
      121 aaacttttat gtaaggcaaa aaatattaat gcaacttctt ctgaagaatt agcatataag
      181 gatgcgactt tcataatctt gtctttgcca accaacctaa aatttaataa gcttgatact
      241 tccattatcg aaatttctgt aagtaatatt ttaaagataa acaaaaaggc tacaattgta
      301 ataaagtcga cagttccaat tggttttaca gaatatttaa ggaatcgatt tcactacaac
      361 gatatcattt tttcacctga gttccttagg gaaggatcaa ctattcatga tcaattgtat
      421 ccttcgagaa ctatagttgg aaatgaatct agaaattctc aattattctt agacatacta
      481 acagatatat cggttgaaaa agactcgcca tctttattag ttggctcttc tgaagcagaa
      541 gcgataaagt tattttcgaa tgcatacttg gcacaaaaaa ttgctttttt taatgagttg
      601 gatacgtttg ctgaaatgca aaatttggac tcaaaaaaaa ttattgaggc tatgggatat
      661 gaccagagaa taggaaattc gcacaataat ccttctttcg gttttggtgg gtactgtctt
      721 cctaaggata ttaagcaatt agagtatcat tttaaagaaa ttccagcacc aattattacc
      781 agtataagtg agtctaattt attaagaaaa attcatatag caaaaacgat tttgaacagc
      841 tcagctaaaa caataggaat ttatagaatt aattccaaaa aagattcgga taattgtagg
      901 gaatcttcta caattgatgt tgctaaactt ctaaaaagca gtggtaagga tgttatcatc
      961 tttgagccct taattaacca aaaaaagttt ttagggtgcc ctttaattaa tgattttaat
     1021 gaatttatta aatattcgga tattatagtt gccaatagaa tagatgatgc tctgagaaaa
     1081 tgtaattcaa aagtttttac acgtgatatt tttcagtatg attaacaaaa acatttttgc
     1141 gaaaaaatat ttttaagta
//
LOCUS       DATTYN010000077         1136 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.77, whole genome shotgun sequence.
ACCESSION   DATTYN010000077 DATTYN010000000
VERSION     DATTYN010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.77"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..207
                     /locus_tag="VB649_001855"
     CDS             <1..207
                     /locus_tag="VB649_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003082558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP1670768.1"
                     /translation="PGKPEVPGKPEVPGESTLIPLKVNYTSGERLENQELPSTGESNN
                     PLILFGVLGLLTGAYMMNSKKKED"
BASE COUNT          403 a          167 c          185 g          381 t
ORIGIN      
        1 ccaggcaaac cagaagtgcc aggtaaacca gaagtaccag gtgaatctac tttaatacct
       61 ctaaaagtga attatacttc aggtgagaga ttggaaaacc aagaattacc ttccacagga
      121 gagtcaaata atccacttat attatttggt gtattggggt tactaactgg ggcatatatg
      181 atgaactcta agaaaaaaga ggattaatct tttgacttaa aatgtcacta agcttttcgc
      241 tatttattgg tgtgaatact ttaattagtt atgcatctct ctccaacaaa attaattaaa
      301 gtgtttcaat ttttcgagat taattcttga aaaagcctat cgagattatt aattccgata
      361 ggcttttgat tttgtatgct aaataataaa gtgtaaatat ttttaaaata ttcaatagat
      421 gttgaatcaa tgtcacgtat aatggtactt agaaagttaa ttttaaagat aattaataga
      481 ggtttaaagt gttcttgagt ccttgataat aattaaagag tggcacgaag aaacatgtaa
      541 gtattttcat agctatcccg aattattaat gcaagagaaa aataccagtc aatttattta
      601 taaaaccttg ctgtcgtata attaccaagt tctacgaatc ggaaaatttt tcatatattc
      661 ctagagcatc gggcatcccg tatctttatt ggggattcgg aggtttcacg aaagagtaag
      721 agatttattc taaccataat tctaagtttg caccagctat tcaaccgacc ttaacaacgg
      781 gtattgaagc tgcagttgtg gctattttac ggtatcttgg taaatagaga ataattacat
      841 gttaagcaaa agcaagctat actaaaatct ccaaatcctg aattggcttt gacagtcttt
      901 ttgataagta agtactcgat aacaagatat atattctttc ctctatttct ccatcatatt
      961 ataagtaata acataaatag agcttgctct aatgatcaaa caatcattaa aagggtttac
     1021 aaaaaatggt ataatactct tactacattc aagtgaggtt cagtcatgtt cgataaatat
     1081 atttttgata cctactatga gcaaatagtc aaaactgtta aaggatttat ttttaa
//
LOCUS       DATTYN010000078         1088 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.78, whole genome shotgun sequence.
ACCESSION   DATTYN010000078 DATTYN010000000
VERSION     DATTYN010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.78"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..908
                     /locus_tag="VB649_001856"
     rRNA            <1..908
                     /locus_tag="VB649_001856"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            994..>1088
                     /gene="rrf"
                     /locus_tag="VB649_001857"
     rRNA            994..>1088
                     /gene="rrf"
                     /locus_tag="VB649_001857"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          284 a          232 c          313 g          259 t
ORIGIN      
        1 tctcaacgag agactcggtg aaattttagt acctgtgaag atgcaggtta cccgcgacag
       61 gacggaaaga ccccatggag ctttactgca gtttgatatt gagtatctgt accacatgta
      121 caggataggt aggagccatt gacttcggga cgccagtttc gaatgaggcg ttgttgggat
      181 actacccttg tgttatggct actctaaccc agataggtta tccctatcgg agacagtgtc
      241 tgacgggcag tttgactggg gcggtcgcct cctaaagagt aacggaggcg cccaaaggtt
      301 ccctcagatt ggttggaaat caatcgcaga gtgtaaaggt ataagggagc ttgactgcga
      361 gagctacaac tcgagcaggg acgaaagtcg ggcttagtga tccggtggta ccgaatggaa
      421 gggccatcgc tcaacggata aaagctaccc tggggataac aggcttatct cccccaagag
      481 ttcacatcga cggggaggtt tggcacctcg atgtcggctc gtcgcatcct ggggctgtag
      541 tcggtcccaa gggttgggct gttcgcccat taaagcggca cgcgagctgg gttcagaacg
      601 tcgtgagaca gttcggtccc tatccgtcgc gggcgtagga aatttgagag gatctgctcc
      661 tagtacgaga ggaccagagt ggacttaccg ctggtgtacc agttgtcttg ccaaaggcat
      721 cgctgggtag ctatgtaggg aagggataag cgctgaaagc atctaagtgc gaagcccccc
      781 tcaagatgag atttcccatg attttatatc agtaagagcc ctgagagatg atcaggtaga
      841 taggttagga gtgtaagtgt agcgatacat gtagcggact aatactaata gctcgaggac
      901 ttatccaaaa agaaatattg acaacgttac ggattcttgt tagactatag gtattcaatt
      961 ttgagtgggt tatgaaaata gcacatttac aagttaagtg acgatagcct aggagataca
     1021 cctgtaccca tgccgaacac agcagttaag ccctagaacg cctgatgtag ttgggggttg
     1081 ccccctgt
//
LOCUS       DATTYN010000079          925 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.79, whole genome shotgun sequence.
ACCESSION   DATTYN010000079 DATTYN010000000
VERSION     DATTYN010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..925
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.79"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(<1..234)
                     /locus_tag="VB649_001858"
     CDS             complement(<1..234)
                     /locus_tag="VB649_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670769.1"
                     /translation="MQQSMTKVKYLWKENNNYIYSTFLTLLLTVILYANSLNLPLKFI
                     SLLFVVSTLLIVFLPKKLEVATIIFILVFGTISA"
     gene            complement(215..>925)
                     /locus_tag="VB649_001859"
     CDS             complement(215..>925)
                     /locus_tag="VB649_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEP1670770.1"
                     /translation="QKLMFSELLSNISFQNSLKLLKESFPLFLNGFLIIYIYTQPKYA
                     IELMTTLGEVALGSQTIFNILFMPAFVMNLLILFFRPYITQMAIALIRGQIKEFNKIQ
                     VQLFAYLGVFSLIALVGSGLFGIPFLSMLYGTNLTDYWVDFMLIMLGGSIGSFATVID
                     NILTAMRKQQLLLIPYTGGFLISLLITNLFVMKYHILGAALSFLITMLVWLGLSIMIY
                     LFIMNRFKKGRVNATIYD"
BASE COUNT          381 a          150 c          115 g          279 t
ORIGIN      
        1 agcagatatc gttccaaata ctaaaataaa aatgatcgta gcaacctcta acttttttgg
       61 taaaaacact atcagtaaag tactcaccac aaaaagaaga ctaataaatt ttaaaggtag
      121 atttaaacta ttggcatata aaataactgt cagaagtaat gtcaaaaaag tcgaataaat
      181 atagttatta ttttctttcc aaagatattt aactttagtc atagattgtt gcattaactc
      241 ttcccttctt aaatctattc ataataaata gataaatcat aatggataat cccaaccaaa
      301 ccaacattgt tattaaaaag ctcaaagcag ctcctaaaat gtgatatttc ataacaaaaa
      361 gattggtaat taataacgaa atcaaaaatc ctcctgtata tggaataaga agaagttgct
      421 gttttctcat agcggttaag atattatcga taactgtcgc aaaactacca atcgagcctc
      481 ctagcataat caacataaag tctacccaat aatccgtaag gttagtacca tatagcattg
      541 ataaaaaggg aataccaaac agaccacttc caactaacgc tatcagtgaa aaaactccta
      601 aataagcaaa caattgaact tgtatcttat taaactcttt tatttgacct ctgattaaag
      661 caatagccat ctgtgtaata taaggtctaa aaaataaaat tagcaaattc ataacaaagg
      721 ctggcataaa taaaatatta aaaattgttt gagagcccaa agcaacttca cctaaagtcg
      781 tcattagttc aatagcgtat tttggttgag tataaatata gataatcaaa aaaccgttta
      841 gaaaaagtgg aaaactttct tttaataact ttaaactgtt ttggaatgaa atattactta
      901 ataattcact aaacatcaac ttttg
//
LOCUS       DATTYN010000080          912 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.80, whole genome shotgun sequence.
ACCESSION   DATTYN010000080 DATTYN010000000
VERSION     DATTYN010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..912
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.80"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            16..>912
                     /locus_tag="VB649_001860"
     CDS             16..>912
                     /locus_tag="VB649_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEP1670771.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKHAPHNAL
                     FGIKADASWTGKSFDTKTQEEYQPGIVTDIVDRFRAYDSWTDSIIDHGKFLNDNPRYK
                     AVIGETDYKKACYAIKAAGYATASSYVELLIQLIEENDLQSWDREALKNNKEETMTTA
                     NEIVQYCVNLANSGMGVDKDGAHGTQCCDLPCFVAKNWFGVDLWGNAIDLLDSASAQG
                     WEVHRMPTEANPKAGATFVQSVPYHQFGHTGIVIEDSDGYTMRTVEQNIDGNADALYV
                     GAPARFNTRDFTGVVGWFYPPYQ"
BASE COUNT          270 a          171 c          225 g          246 t
ORIGIN      
        1 agataaggag gacagatgac ctttttagat gatattaagc agggctgttt agatggctgg
       61 actaagtata aaatcttgcc atccttgaca gctgctcagg ctattttaga gagcggttgg
      121 ggcaaacatg caccacataa cgctttattt ggtattaagg ctgatgcgag ctggacaggt
      181 aagtcttttg acactaaaac tcaggaggag taccagcctg gtatcgtcac ggatattgtg
      241 gaccgattta gggcctatga tagttggact gacagtatta ttgatcatgg caaattttta
      301 aacgataatc cacgctacaa agcagttatc ggtgagactg actataaaaa agcttgttac
      361 gctattaaag cagctggata cgctacggca agtagctatg tcgaactttt aatccaactg
      421 attgaggaaa acgacttaca aagttgggat agagaagctc ttaaaaataa taaggaggaa
      481 acgatgacaa ccgcaaacga aattgtacaa tactgtgtta accttgctaa ttcaggcatg
      541 ggtgttgaca aagacggtgc tcacgggacg caatgctgtg acttgccttg ttttgtcgct
      601 aaaaattggt ttggtgttga tctttggggc aatgcgattg atttattaga cagcgcaagt
      661 gcgcaaggct gggaagtcca tcgtatgcca acagaggcaa acccaaaagc aggcgctaca
      721 tttgtccaat cagtgccgta tcatcaattt ggacatacgg gaattgtcat tgaggatagc
      781 gacggctaca ctatgcggac tgttgaacaa aacattgatg gcaatgcaga cgccttatat
      841 gtcggcgcac cagctcgttt taatactcgt gactttactg gcgttgttgg atggttttac
      901 ccaccatatc aa
//
LOCUS       DATTYN010000081          722 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.81, whole genome shotgun sequence.
ACCESSION   DATTYN010000081 DATTYN010000000
VERSION     DATTYN010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..722
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.81"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(3..76)
                     /locus_tag="VB649_001861"
     tRNA            complement(3..76)
                     /locus_tag="VB649_001861"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(40..42),aa:Arg,seq:acg)
     gene            complement(93..177)
                     /locus_tag="VB649_001862"
     tRNA            complement(93..177)
                     /locus_tag="VB649_001862"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(141..143),aa:Leu,seq:taa)
     gene            complement(186..257)
                     /locus_tag="VB649_001863"
     tRNA            complement(186..257)
                     /locus_tag="VB649_001863"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(223..225),aa:Gly,seq:gcc)
     gene            complement(270..342)
                     /locus_tag="VB649_001864"
     tRNA            complement(270..342)
                     /locus_tag="VB649_001864"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(307..309),aa:Thr,seq:tgt)
     gene            complement(353..434)
                     /locus_tag="VB649_001865"
     tRNA            complement(353..434)
                     /locus_tag="VB649_001865"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(398..400),aa:Leu,seq:tag)
     gene            complement(440..512)
                     /locus_tag="VB649_001866"
     tRNA            complement(440..512)
                     /locus_tag="VB649_001866"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(477..479),aa:Lys,seq:ttt)
     gene            complement(544..616)
                     /locus_tag="VB649_001867"
     tRNA            complement(544..616)
                     /locus_tag="VB649_001867"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(581..583),aa:Asp,seq:gtc)
     gene            complement(634..706)
                     /locus_tag="VB649_001868"
     tRNA            complement(634..706)
                     /locus_tag="VB649_001868"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(671..673),aa:Val,seq:tac)
BASE COUNT          187 a          206 c          159 g          170 t
ORIGIN      
        1 gatgcaccct agaggagtcg aacctctaac cgcctgattc gtagtcaggt actctatcca
       61 gttgagctaa gggtgctatt tcaaaaaaat aatgccgagg accggaatcg aaccggtacg
      121 atgtaaacca tcgcaggatt ttaagtcctg tgcgtctgcc agttccgcca ccccggctcc
      181 tcaaaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt gatgttctac
      241 cactgaacta cgttcgcaac taatctcaat gccggctaca tgacttgaac acgcgaccct
      301 ctgattacaa atcagatgct ctaccaactg agctaagccg gctaatcttt tatgcgggtt
      361 aagggacttg aacccccacg ccgttaagcg ccagatccta aatctggtgc gtctgccaat
      421 tccgccaaac ccgcttttat gacccgtact gggctcgaac cagtgaccca ttgattaaaa
      481 gtcaattgct ctaccaactg agctaacgag tcttttcttc aaaaaatatg actactcttt
      541 gaacggtccc gacgggaatc gaacccgcga tcttcgccgt gacagggcga cgtgataacc
      601 gctacactac gggacctgta ttttccaata ctatgggagt taacgggatc gaaccgctga
      661 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcccattg agtgtgtcat
      721 ta
//
LOCUS       DATTYN010000082          676 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.82, whole genome shotgun sequence.
ACCESSION   DATTYN010000082 DATTYN010000000
VERSION     DATTYN010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..676
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.82"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..>676
                     /locus_tag="VB649_001869"
     CDS             <1..>676
                     /locus_tag="VB649_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HEP1670772.1"
                     /translation="DGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEEKSNEIVA
                     IPQLLRTIDIRKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYDDIALYFSD
                     VNLLEELQENAQYYQTVEKSRGQIEVREYWVSSDIKWLCQNRPKWHKLRGIGITRNTI
                     DKDGQLSQENRYFIFSFKPDVLTFANCVRDHWQIESMHWLLDVVYHEDHHQTLDKRAA
                     FNLNLIR"
BASE COUNT          215 a          108 c          159 g          194 t
ORIGIN      
        1 gacggtaaaa cgattcgagg caatcgaggt aaaaatcaga agcctgttca tattgtaacg
       61 gcttatgatg ggggtcatca tcttagtttg ggacaggtag cggttgagga gaaaagtaat
      121 gaaattgttg ccattcctca gttattgcgg acaattgata tccgtaaaag cattgtaacg
      181 atagacgcaa tgggcacgca gacggctatc gttgatacga ttataaaagg taaagcagac
      241 tattgcttag ccgtcaaagg aaatcaagaa acactttatg atgatattgc tctttatttt
      301 agtgatgtca acttattgga agaactccaa gaaaatgcgc agtattatca gactgttgaa
      361 aaatctaggg gacagattga agttagagaa tactgggtgt cttccgatat caaatggttg
      421 tgtcaaaacc gtcccaaatg gcataagtta cgtggtattg ggattactcg taacacgatt
      481 gataaggatg gtcagctgag tcaagagaat cgttatttta tctttagctt taagccggat
      541 gtcctcacat ttgccaattg tgtacgagat cattggcaga tagagagtat gcactggtta
      601 ttggacgttg tttatcatga agatcatcat cagacattgg ataaaagagc cgcatttaac
      661 ctaaatctta tccgaa
//
LOCUS       DATTYN010000083          642 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.83, whole genome shotgun sequence.
ACCESSION   DATTYN010000083 DATTYN010000000
VERSION     DATTYN010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.83"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(155..>642)
                     /locus_tag="VB649_001870"
     CDS             complement(155..>642)
                     /locus_tag="VB649_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEP1670773.1"
                     /translation="PSVAASSEETPTPSTPAAPETPAESEAPAQPAESEESSVAASSE
                     ETPTPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVSEQTVQQPTSKRSSDKKEE
                     QEQSYSPNRSLSRQVRAHESGKYLPSTGEKAQPLFIATMTLMSLFGSLLVTKRQKETK
                     K"
BASE COUNT          164 a          109 c          156 g          213 t
ORIGIN      
        1 catcttttat tacagcaact gaagagataa gcaaaagaca attgttgaca gctatttgtc
       61 ctaacttctt tttgatgagg cagcacatct aaaaaaatag agagaaccaa attggttctc
      121 tctattaaat aagctcttat cagtttaagt aatactattt tttagtttct ttttggcgtt
      181 ttgtgactaa aagactgcca aatagagaca tcaaagtcat agtagctata aagagtggct
      241 gtgctttttc acctgttgaa ggcaagtact tacctgactc atgggcccta acctgtcttg
      301 acaatgagcg atttggagag taagactgtt cttgctcttc ttttttatca gaagatctct
      361 ttgaagttgg ttgttgaacg gtttgttctg aaacaagtga agaggctgct ggtttttcag
      421 ctgctgaaga tggcttatca gagtctttag taacagctgg tggcgtctga gtctctgatt
      481 cagctggagt tgatggagtt ggggtttcct cagaagaagc tgctactgaa gattcttcac
      541 tctcagctgg ttgagctgga gcctctgatt cagctggggt ttctggggct gctggagttg
      601 atggagttgg ggtttcctca gaagaagctg ctactgaagg tt
//
LOCUS       DATTYN010000084          612 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.84, whole genome shotgun sequence.
ACCESSION   DATTYN010000084 DATTYN010000000
VERSION     DATTYN010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..612
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.84"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            56..403
                     /locus_tag="VB649_001871"
     CDS             56..403
                     /locus_tag="VB649_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEP1670774.1"
                     /translation="MFFTFEKIKELADKQGISLNQLEEKLGFSRNTIYNMKKSTPNVE
                     RVSRIADYFNVSTDYLLGRTDNPKIASDKDDNTVDLKKAVAGSMAFDGKPLTEDEINY
                     LADVFEAQLKMKK"
BASE COUNT          228 a           87 c          111 g          186 t
ORIGIN      
        1 ttgtagtaaa tttattaaat attttttgtc atgccttaga aaggttgata aatcaatgtt
       61 ttttacgttt gagaaaatca aggaattggc tgacaaacaa ggtatttcac taaatcaact
      121 tgaggaaaaa cttggtttta gtagaaatac tatctacaac atgaagaaat ctacacctaa
      181 tgttgagcga gtttcaagaa ttgcagatta cttcaatgtc agcaccgact acctacttgg
      241 taggacagat aatccaaaga ttgcatccga taaagacgat aataccgttg atttaaaaaa
      301 agccgtagct ggttcaatgg cttttgatgg aaagcctcta acagaggatg aaattaatta
      361 tttagcagat gtcttcgaag ctcaattaaa aatgaaaaag taggataatg ttatgtcagc
      421 agaggaatta tgcaaatcgc acggaatacc aatatgctat tttgaggggg atgtcattga
      481 gagaaatgga ttttataatc cgcaattcaa tgctatcgct attaactcaa gactttatgg
      541 aatccataaa gataaagtta tttatcacga attcggtcat aaagatcata ctgaaaacta
      601 ttataaatta aa
//
LOCUS       DATTYN010000085          585 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.85, whole genome shotgun sequence.
ACCESSION   DATTYN010000085 DATTYN010000000
VERSION     DATTYN010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..585
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.85"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(97..279)
                     /locus_tag="VB649_001872"
     CDS             complement(97..279)
                     /locus_tag="VB649_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEP1670775.1"
                     /translation="MDNFLELQFEELVNISGGKGNIGSAIGGCLGGMLIAAAGGPITG
                     GAAAFVCVASGIAAYQ"
     gene            complement(294..539)
                     /locus_tag="VB649_001873"
     CDS             complement(294..539)
                     /locus_tag="VB649_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEP1670776.1"
                     /translation="MIKFAEEIQKEELFHIIGGYSATDCKNHLIGGITSGAIAGGVGA
                     GMATLGVGGVAGAFAGAHVGAIAGGLTCVGGMLFNGK"
BASE COUNT          195 a          152 c           55 g          183 t
ORIGIN      
        1 attactttac ttgcattttc tcttacctct ttatccttca aaaaaatttg ggaaagtatt
       61 agacaaatta aaccgagtat tataactata atcatatcat tgataagctg caattccaga
      121 tgctacacat acaaatgctg ccgcacctcc agttattgga cctcctgctg cagctataag
      181 catcccacct aagcaccctc cgatagcaga tccaatattt ccttttccac cagaaatatt
      241 tactaattct tcaaactgta attctaaaaa attatccatt tttcacctca aaattatttt
      301 ccattaaata acataccacc aacgcaagtt aatccacccg caatagcacc tacatgtgca
      361 cctgcaaacg cacctgcaac tcctccaaca cctaaagtag ccatacctgc tccaacacca
      421 cctgcaatag cacctgaagt aataccacca attaaatgat ttttacaatc tgtagcacta
      481 taacctccaa taatatggaa caactcttct ttttgtattt cttctgcaaa ttttatcata
      541 actttaaaaa cctttctaaa atgttatatt catcttgttg caact
//
LOCUS       DATTYN010000086          572 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.86, whole genome shotgun sequence.
ACCESSION   DATTYN010000086 DATTYN010000000
VERSION     DATTYN010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.86"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..>572
                     /locus_tag="VB649_001874"
     CDS             <1..>572
                     /locus_tag="VB649_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pyrogenic exotoxin SpeK"
                     /protein_id="HEP1670777.1"
                     /translation="NRRLKDIYGKKIIEKTNIPINAKQGTHLIFNTNENTTVWDDNTF
                     TKVISSNLSPSQERMFNVGDHVNIFAIVKSYQVVCKDQFNYIDGGIIKTSDVKPEEKA
                     IYINIISDKELRALTAKDKLTFKNNMVTLQEIDVRLRKSLMGDSKIKLYEYGSLYIKG
                     FWDIHYKDGTTRHTNLFSYPDYTDNEIIDV"
BASE COUNT          234 a           66 c           96 g          176 t
ORIGIN      
        1 taatagaaga ttaaaagaca tttatggtaa aaaaattatt gaaaaaacta atataccgat
       61 aaatgccaaa cagggaacgc atttgatttt taatacgaat gaaaatacta cagtttggga
      121 tgataatact tttacaaaag tcatatctag taatctttca ccttcacagg aaagaatgtt
      181 taatgttggt gatcatgtga atatttttgc tatcgtaaaa tcatatcagg ttgtatgcaa
      241 ggatcaattc aattatattg atgggggaat aataaaaaca agtgatgtaa aaccagaaga
      301 aaaagcaatt tatattaata ttattagtga caaagaacta cgagcattaa cagctaaaga
      361 taagcttacc ttcaaaaata atatggtaac ccttcaagaa attgatgtta gacttaggaa
      421 aagtttgatg ggagatagca aaataaaatt gtatgaatat ggttctttgt atataaaagg
      481 tttttgggac attcattata aagatggtac cactagacac accaatttat ttagctaccc
      541 agattataca gataatgaaa taattgacgt tg
//
LOCUS       DATTYN010000087          557 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.87, whole genome shotgun sequence.
ACCESSION   DATTYN010000087 DATTYN010000000
VERSION     DATTYN010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.87"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..233
                     /locus_tag="VB649_001875"
     CDS             <1..233
                     /locus_tag="VB649_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEP1670778.1"
                     /translation="LDDLIGHQNENKDAPSNLKDVTEDLHSDPEKTLADENKTVLEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLI"
     gene            230..430
                     /locus_tag="VB649_001876"
     CDS             230..430
                     /locus_tag="VB649_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670779.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREEFVFCDTPIDEVIKRLLDD"
     gene            423..>557
                     /locus_tag="VB649_001877"
     CDS             423..>557
                     /locus_tag="VB649_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEP1670780.1"
                     /translation="MTSLDLLGKDYYSRESAIRYWSISQYKRFKECEARALAELQGNW
                     T"
BASE COUNT          189 a           81 c          129 g          158 t
ORIGIN      
        1 gtctagatga tctaattggt caccagaatg aaaataagga tgctcctagc aatttaaaag
       61 acgtgactga agatttacat tcagatccag aaaaaacgct cgcagacgaa aataagactg
      121 ttttagaaga tacctcttat ccggcagatg aaattcccga ttttgatcaa gaaacaggcg
      181 aaattaaagc tagcgaaggc aacttatttg ataacctcgg agacttaata tgattaaact
      241 tgtaaaaatt gaaggatatt atattaatcc agaatatgtt gttggcgttt gggaaagatc
      301 tgctttaaat tttgacgatt tagatgaaaa agtagtggtt attcaattcg ttggagatag
      361 ggaaagggaa gagtttgtct tttgcgatac acctattgat gaagtaatta agaggttgct
      421 agatgactag tttagacttg ctcggaaagg actattacag ccgtgaatca gctatcaggt
      481 actggtccat tagtcagtac aagcgtttta aagagtgcga agcgcgggcg cttgctgaat
      541 tacaagggaa ttggaca
//
LOCUS       DATTYN010000088          550 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.88, whole genome shotgun sequence.
ACCESSION   DATTYN010000088 DATTYN010000000
VERSION     DATTYN010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.88"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            <1..>550
                     /locus_tag="VB649_001878"
     CDS             <1..>550
                     /locus_tag="VB649_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEP1670781.1"
                     /translation="FVLEELYLELIDDLSDGNNQTLLDIINDDKNIEEIASLVEDKTE
                     VEGNFYVRKSLPQDINQNAIDIATMDPYAFEDLCKKLLEMEGFLNVHRKGGSGDMGVD
                     VVGEHFNGNKKEFWLVQCKRWVSNVGSTPLQRLVSERERLGAQQIACYTTSDYTSDAK
                     IVAKSQGVIIVNGKELIQMLDK"
BASE COUNT          207 a           68 c          116 g          159 t
ORIGIN      
        1 gatttgtact tgaagaatta tatttagaat taattgacga tttatctgat ggtaacaatc
       61 aaacacttct tgatataatt aatgatgata aaaatattga agagattgct tcgttagtag
      121 aggataagac ggaagttgaa ggtaatttct atgtaagaaa atcgctaccg caagacatta
      181 atcaaaatgc aattgatata gcaactatgg acccatatgc ttttgaagat ttatgtaaga
      241 aattactcga aatggaggga tttttaaatg ttcaccgaaa aggtggaagt ggagatatgg
      301 gagttgatgt cgtaggagag catttcaatg gaaataaaaa agaattttgg ctcgtacaat
      361 gtaagcgttg ggttagtaat gtaggttcaa ctccgttaca acgacttgta tcagaaagag
      421 aacgattggg agcacaacaa atagcatgtt acactacctc agattatact tctgatgcca
      481 agattgttgc aaaatcgcaa ggagtcataa tagttaatgg aaaagaacta atacaaatgc
      541 tagataaaca
//
LOCUS       DATTYN010000089          546 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.89, whole genome shotgun sequence.
ACCESSION   DATTYN010000089 DATTYN010000000
VERSION     DATTYN010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..546
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.89"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(<1..287)
                     /locus_tag="VB649_001879"
     CDS             complement(<1..287)
                     /locus_tag="VB649_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEP1670782.1"
                     /translation="MTQFTTELLNFLAQKQDIDEFFRSSLEIAMNDLLQVELSAFLGY
                     EPYEKEGCNTGNSRNGTYSRQFETKYGLVNLIIPRDRNGEFSPVLLPSYARR"
BASE COUNT          167 a          105 c           86 g          188 t
ORIGIN      
        1 cgtctagcat aagatggtaa taaaactggt gaaaactcgc cgtttcgatc tcttgggatg
       61 attaaattga ctaagccata ctttgtttca aactgacgag aataagtccc attacggcta
      121 ttacctgtgt tgcaaccttc tttttcataa ggttcataac caagaaaagc tgatagttca
      181 acttgcaaga ggtcattcat agctatttct aaagaggagc gaaaaaattc atcaatatct
      241 tgtttttgtg ctaggaagtt aagtaattct gtggtaaact gagtcatggg aataaatctc
      301 tttctagtaa gtttcgcaac tctactatac aggatttatt cctttttgtg tgtttacaca
      361 agatatttta cactacccaa ttaccaccct caaccttggc aagcttttct atagtcattt
      421 gatgaaatgt ttccagtttc tttatctcca tatcgaataa ctccttttca taattcttaa
      481 atttgtctcg ttgcaacctc gactagtaca gaatatcata aagaacagta tcatggcttc
      541 aaaatc
//
LOCUS       DATTYN010000090          531 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.90, whole genome shotgun sequence.
ACCESSION   DATTYN010000090 DATTYN010000000
VERSION     DATTYN010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.90"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(90..173)
                     /locus_tag="VB649_001880"
     tRNA            complement(90..173)
                     /locus_tag="VB649_001880"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(137..139),aa:Leu,seq:caa)
     gene            complement(193..264)
                     /locus_tag="VB649_001881"
     tRNA            complement(193..264)
                     /locus_tag="VB649_001881"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(230..232),aa:Gln,seq:ttg)
     gene            complement(273..345)
                     /locus_tag="VB649_001882"
     tRNA            complement(273..345)
                     /locus_tag="VB649_001882"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(310..312),aa:His,seq:gtg)
     gene            complement(357..427)
                     /locus_tag="VB649_001883"
     tRNA            complement(357..427)
                     /locus_tag="VB649_001883"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(393..395),aa:Trp,seq:cca)
     gene            complement(434..514)
                     /locus_tag="VB649_001884"
     tRNA            complement(434..514)
                     /locus_tag="VB649_001884"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(478..480),aa:Tyr,seq:gta)
BASE COUNT          154 a          135 c          114 g          128 t
ORIGIN      
        1 ccttaccagt aatataagaa attgtaccac gtagctacag cctaagatca aaacaaaaaa
       61 caaggtttac aaaccttgtt tttcaagtat accggcggcc ggggtcgaac cggcacgtcc
      121 ttgcggacac tggattttga gtccagcgcg tctgccaatt ccgccacgcc ggctttaaat
      181 ataaaattta aactggggta gctggattcg aaccaacgca tgagggagtc aaagtccctt
      241 gccttaccgc ttggctatac cccaataaaa taggcgagtg atgggaatcg aacccacgaa
      301 tgtcagagcc acaatctgat gtgttaacca cttcaccaca cccgccatat ttctaacacg
      361 ggcagtagga atcgaaccca cactgaaggt tttggagacc ttagttctac ctttaaacta
      421 tgcccgttta ggatggaaag agagggattc gaacccccga acccgaagga gcggatttac
      481 agtccgccgc gtttagcctc ttcgctatct ttccgtaaaa tattaaattt t
//
LOCUS       DATTYN010000091          519 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.91, whole genome shotgun sequence.
ACCESSION   DATTYN010000091 DATTYN010000000
VERSION     DATTYN010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.91"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            117..341
                     /locus_tag="VB649_001885"
     CDS             117..341
                     /locus_tag="VB649_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEP1670783.1"
                     /translation="MTYFRLKKELNWSLRNKGIVVYEGNQKLQIAINTGKNNSEKVFF
                     DTFFEVVRAAATFFTAKNICFGLGLLRSQK"
BASE COUNT          184 a           67 c           96 g          172 t
ORIGIN      
        1 aataaacaaa taggagggca attgtttaac tggttaatta gaatttttgt tattttcagg
       61 aagatactca gggctttttt ataagttgat gtattaacaa aagataaaga ggtttcatga
      121 cttattttag attaaaaaaa gaattaaact ggtcactaag aaataaagga attgtagttt
      181 acgaagggaa tcaaaaactt cagatagcca ttaatacagg taaaaataac agtgaaaaag
      241 tcttttttga tacttttttt gaggtggttc gggcggcagc gacttttttc acagcaaaaa
      301 acatctgttt tggtcttggc ttacttcgtt cgcagaaata ggaaatcggg tatcacatta
      361 gcagagtagt tcatgctttt tgagcatcac actgggtctg tctacgttct aaaagctttt
      421 gtcatttttg tatcataccc cctacaagta gaaaaagcat aataaagaaa atttataaac
      481 aaaaatggct agtattatca aggaatttat caatttttg
//
LOCUS       DATTYN010000092          468 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.92, whole genome shotgun sequence.
ACCESSION   DATTYN010000092 DATTYN010000000
VERSION     DATTYN010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.92"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
BASE COUNT          155 a           51 c           92 g          170 t
ORIGIN      
        1 tactttgagt agtaacgata atatttaatt ttttgatgga ttactttaat tgactttagt
       61 gtgttagatg ccagtttgga tttttgatat ttgtgttgag tttaaaagat aaaaacactt
      121 gatgaaaatc tgttttttct tagaaagggg accagtatga ttgagacgct aatgagtacg
      181 ttggaaatgg ttagaaaaaa aatcctagta ggactgcaat cgaagatgac tttgaggaat
      241 ataaaaagag aaatctacca atctttgtca gtgaagatga tagtgtgatc tattatagac
      301 cagggttcat ttttaatgaa ttctatccca atatttcagg ttggagacaa gaactaaaga
      361 ctaagcttac tagtatttct ttaatttctt tacattttat tggtgttgtt gacgaacaaa
      421 aaaaggggga atatctaggt tctttttctg atacatctga attcttaa
//
LOCUS       DATTYN010000093          376 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.93, whole genome shotgun sequence.
ACCESSION   DATTYN010000093 DATTYN010000000
VERSION     DATTYN010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.93"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
BASE COUNT          156 a           52 c           54 g          114 t
ORIGIN      
        1 aaaaaaaggt caaagacttt ctgacaccaa ataaaaatag aattttttct aactaaaaat
       61 aatagcacaa tctttggcag caatctgaat tgtttttcca taaaagattt aagcacttac
      121 gtttgcttaa aatataggtt atgtgacgtg cgtgcaagat cagattataa caaaatagtt
      181 ccaaataagc ctatcactga gaaagcatca cagaagggtt aaactttttt tgtattagcg
      241 ttttatcagt acaacctaac acttattttt ataaaaaaat aaaaaagcta ttgacaatct
      301 tatacaagat aacgtatact aataaagctg ttgtaaatat ggtaaagcaa tagatgctat
      361 caggaaaaaa tgtgaa
//
LOCUS       DATTYN010000094          354 bp    DNA     linear   BCT 27-DEC-2023
DEFINITION  TPA_asm: Streptococcus pyogenes isolate DMG1900024
            SAMN35797714-rid20199843.denovo.94, whole genome shotgun sequence.
ACCESSION   DATTYN010000094 DATTYN010000000
VERSION     DATTYN010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35797714
            Sequence Read Archive: SRR25000989
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 13-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001983231.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001983231.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/14/2023 01:24:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,886
            CDSs (total)                      :: 1,849
            Genes (coding)                    :: 1,792
            CDSs (with protein)               :: 1,792
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 29
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 34 of 57
            Pseudo Genes (incomplete)         :: 19 of 57
            Pseudo Genes (internal stop)      :: 20 of 57
            Pseudo Genes (multiple problems)  :: 15 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Streptococcus pyogenes"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35797714-rid20199843.denovo.94"
                     /serotype="EMM4.5"
                     /isolate="DMG1900024"
                     /host="Homo sapiens"
                     /db_xref="taxon:1314"
                     /country="New Zealand: Auckland"
                     /collection_date="2018"
                     /collected_by="University of Otago,Wellington"
                     /note="genotype: ST1027"
     gene            complement(91..>354)
                     /locus_tag="VB649_001886"
     CDS             complement(91..>354)
                     /locus_tag="VB649_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEP1670784.1"
                     /translation="SDTIVETAKTGTFTLDVAEINIRRWPSLASEVVGSYKQGDTVSF
                     DSEGYANGYYWISYVGGSGMRNYLGIGQTDKDGNRISIWGKLS"
BASE COUNT           96 a           94 c           61 g          103 t
ORIGIN      
        1 cttccactgt agccaatctg gaacacgaaa aaaatccctt agacataaca acctaaggga
       61 tttacttgtc ttatctcgga gctttacctc ctaacttaat ttaccccaaa tactgatgcg
      121 attcccatct ttatcagtct gtccaatacc taggtagtta cgcatacctg agccgccaac
      181 atagctaatc cagtagtaac cgttggcata accctcactg tcaaagctga cagtatcacc
      241 ttgcttatag ctacctacta cttcactggc taggcttggc cagcgtctga tattgatctc
      301 tgcaacatca agagtaaagg tgcctgtttt tgctgtctct acgatagtgt cgga
//
